Homeobox domain-containing protein

Overview
NameHomeobox domain-containing protein
Smed IDSMED30005064
Length (bp)1019
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Homeobox domain-containing protein (SMED30005064) t-SNE clustered cells

Violin plots show distribution of expression levels for Homeobox domain-containing protein (SMED30005064) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Homeobox domain-containing protein (SMED30005064) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Homeobox domain-containing protein (SMED30005064) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30005064

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30005064h1SMcG0000941 SmedASXL_011256SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30005064h1SMcG0000941 dd_Smed_v4_18719_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30005064h1SMcG0000941 dd_Smed_v4_18719_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
dorsal ventral margin of the whole animalSMED30005064h1SMcG0000941 dd_Smed_v4_18719_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: BARHL2 (BarH like homeobox 2 [Source:HGNC Symbol;Acc:HGNC:954])

HSP 1 Score: 163.696 bits (413), Expect = 1.552e-46
Identity = 75/104 (72.12%), Postives = 91/104 (87.50%), Query Frame = 3 
Query:  324 GKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA 635
             KKPRKARTAF+DHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY+ YHP    ++ +MD+
Sbjct:  229 AKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPYF-YHPS---LLGSMDS 327
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: BARHL1 (BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:953])

HSP 1 Score: 160.614 bits (405), Expect = 4.779e-46
Identity = 79/129 (61.24%), Postives = 99/129 (76.74%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA-----MLKQQQALSMCRNNPFLQQIL 698
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D      + +   A       P + +IL
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLDPGAALYLYRGPSAPPPALQRPLVPRIL 299
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: BARHL1 (BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:953])

HSP 1 Score: 160.614 bits (405), Expect = 4.779e-46
Identity = 79/129 (61.24%), Postives = 99/129 (76.74%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA-----MLKQQQALSMCRNNPFLQQIL 698
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D      + +   A       P + +IL
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLDPGAALYLYRGPSAPPPALQRPLVPRIL 299
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: BARX2 (BARX homeobox 2 [Source:HGNC Symbol;Acc:HGNC:956])

HSP 1 Score: 87.4261 bits (215), Expect = 3.504e-19
Identity = 40/65 (61.54%), Postives = 48/65 (73.85%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVG 521
            KKPR++RT FT+ QL  LEK F++QKYLS  DR++LA  L LT  QVKTWYQNRR KWK+    G
Sbjct:  131 KKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKG 195
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: GBX1 (gastrulation brain homeobox 1 [Source:HGNC Symbol;Acc:HGNC:4185])

HSP 1 Score: 85.8853 bits (211), Expect = 3.953e-18
Identity = 55/152 (36.18%), Postives = 80/152 (52.63%), Query Frame = 3 
Query:   63 KVMSS-ISKFENTKENPKNQVNYQKSNGSFMISE---LIDENQQNKLSILALNNNLKNQWTDDDQESESTGSIDLGSDDVSNCNQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKR 506
            KV SS   K E +  +P    + Q+  GS   SE    +D +     ++L     LK             GS+  G+++ +     G++  G K R+ RTAFT  QL ELEK F  +KYLS+ +R ++A  L+L++ QVK W+QNRR KWKR
Sbjct:  183 KVYSSDEEKLEASAGDPAG--SEQEEEGSGGDSEDDGFLDSSAGGPGALLGPKPKLK-------------GSLGTGAEEGAPVTA-GVTAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 318
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-31 (Homeobox protein ceh-31 [Source:UniProtKB/Swiss-Prot;Acc:Q22910])

HSP 1 Score: 150.599 bits (379), Expect = 2.399e-43
Identity = 86/171 (50.29%), Postives = 108/171 (63.16%), Query Frame = 3 
Query:  105 NPKNQVNYQKSNG--------SFMISELIDENQQNKLSILALNNNLKNQWTDDDQESESTGSIDLGSDDVS-NCNQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYW 590
            +P NQ+  Q S+G        SF IS+L+D    +         N  +        SES  S  +GS +   + N+       KK RKART FTD QL ELE  FE+QKYLSVQDRMELA ++ LTDTQVKTWYQNRRTKWKRQ +VG++LL +AGN AAVQ++++TNPYW
Sbjct:   17 DPTNQLAAQSSSGGAKINLNSSFRISDLLDPTSHS--------TNEPDPSPTSINSSESPSSPRIGSPNTERSVNESPTCVGSKKARKARTIFTDKQLQELENTFEKQKYLSVQDRMELAHRMGLTDTQVKTWYQNRRTKWKRQASVGMDLLHDAGNMAAVQQLLRTNPYW 179
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-30 (Homeobox protein ceh-30 [Source:UniProtKB/Swiss-Prot;Acc:Q22909])

HSP 1 Score: 144.05 bits (362), Expect = 3.669e-41
Identity = 65/97 (67.01%), Postives = 79/97 (81.44%), Query Frame = 3 
Query:  300 NQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYW 590
            ++ G   S KK RKART FTD QL ELE  FE+QKYLSVQDRM+LA ++ LTDTQVKTWYQNRRTKWKRQ T G++LL+E GN +AVQ +I+++PYW
Sbjct:   84 DRMGSPGSCKKSRKARTIFTDKQLQELENTFEKQKYLSVQDRMDLAHRMGLTDTQVKTWYQNRRTKWKRQATSGMDLLSEPGNLSAVQNLIRSSPYW 180
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-30 (Homeobox protein ceh-30 [Source:UniProtKB/Swiss-Prot;Acc:Q22909])

HSP 1 Score: 144.05 bits (362), Expect = 3.669e-41
Identity = 65/97 (67.01%), Postives = 79/97 (81.44%), Query Frame = 3 
Query:  300 NQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYW 590
            ++ G   S KK RKART FTD QL ELE  FE+QKYLSVQDRM+LA ++ LTDTQVKTWYQNRRTKWKRQ T G++LL+E GN +AVQ +I+++PYW
Sbjct:   84 DRMGSPGSCKKSRKARTIFTDKQLQELENTFEKQKYLSVQDRMDLAHRMGLTDTQVKTWYQNRRTKWKRQATSGMDLLSEPGNLSAVQNLIRSSPYW 180
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-9 (Homeobox protein ceh-9 [Source:UniProtKB/Swiss-Prot;Acc:P56407])

HSP 1 Score: 78.9518 bits (193), Expect = 1.245e-17
Identity = 37/59 (62.71%), Postives = 46/59 (77.97%), Query Frame = 3 
Query:  330 KPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKR 506
            K +KART F+  Q+ ELEK FE +KYLS  DR ELA +L +T+TQVK W+QNRRTKWK+
Sbjct:   69 KRKKARTTFSGKQVFELEKQFEAKKYLSSSDRSELAKRLDVTETQVKIWFQNRRTKWKK 127
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-1 (Homeobox protein ceh-1 [Source:UniProtKB/Swiss-Prot;Acc:P53547])

HSP 1 Score: 78.1814 bits (191), Expect = 3.464e-17
Identity = 41/85 (48.24%), Postives = 57/85 (67.06%), Query Frame = 3 
Query:  270 DLGSDDVSNCNQRGLSQSGK-----KPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQ 509
            D  SD+ ++  Q+  +  GK     K R+ARTAFT  QL  LE  F+  +YLSV +R+ LA +L+L++TQVK W+QNRRTKWK+ 
Sbjct:   16 DSNSDEATH--QKSPADGGKSSRKLKMRRARTAFTYEQLVALENKFKTSRYLSVVERLNLAIQLQLSETQVKIWFQNRRTKWKKH 98
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: B-H1 (gene:FBgn0011758 transcript:FBtr0074430)

HSP 1 Score: 154.451 bits (389), Expect = 3.395e-42
Identity = 84/144 (58.33%), Postives = 99/144 (68.75%), Query Frame = 3 
Query:  156 SELIDENQQNKLSILALNNNLKNQWTDDDQESESTGSIDLGSDDVSNCNQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPY 587
            S+  +EN+      +  ++   N   DDD  S  +GS    + D+S     GLS   KK RKARTAFTDHQL  LEK+FE+QKYLSVQ+R ELA KL L+D QVKTWYQNRRTKWKRQT VGLELLAEAGNFAA QR+   +PY
Sbjct:  252 SDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGS----TSDMS-----GLS---KKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPY 383
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: B-H2 (gene:FBgn0004854 transcript:FBtr0334458)

HSP 1 Score: 147.902 bits (372), Expect = 8.914e-42
Identity = 72/94 (76.60%), Postives = 77/94 (81.91%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRII-QTNPY---WTY 596
            KK RKARTAFTDHQL  LEK+FE+QKYLSVQDRMELA KL L+D QVKTWYQNRRTKWKRQT VGLELLAEAGN+AA QR+     PY   W Y
Sbjct:   36 KKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPY 129
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: B-H2 (gene:FBgn0004854 transcript:FBtr0074429)

HSP 1 Score: 150.599 bits (379), Expect = 2.041e-40
Identity = 72/94 (76.60%), Postives = 77/94 (81.91%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRII-QTNPY---WTY 596
            KK RKARTAFTDHQL  LEK+FE+QKYLSVQDRMELA KL L+D QVKTWYQNRRTKWKRQT VGLELLAEAGN+AA QR+     PY   W Y
Sbjct:  378 KKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPY 471
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: CG11085 (gene:FBgn0030408 transcript:FBtr0073656)

HSP 1 Score: 99.7525 bits (247), Expect = 7.644e-24
Identity = 48/74 (64.86%), Postives = 57/74 (77.03%), Query Frame = 3 
Query:  312 LSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELL 533
            LS+SG+KPR+ RTAFT  QL  LE+ F  QKYLSV DR ++A  L L++TQVKTWYQNRRTKWKRQ  + LE L
Sbjct:  153 LSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQL 226
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: lms (gene:FBgn0034520 transcript:FBtr0342702)

HSP 1 Score: 90.1225 bits (222), Expect = 6.555e-20
Identity = 49/100 (49.00%), Postives = 62/100 (62.00%), Query Frame = 3 
Query:  237 DDQESESTGSIDLGSDDVSNCNQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLA 536
            DD   +    IDL SDD +     GL    KK  + RTAF+  Q+  LE  FE+ KYLSV  R  LA +L+LT+TQ+K W+QNRRTKWKR+ T  +E LA
Sbjct:   61 DDNMDDGKSDIDLASDDGN-----GLGDDRKK--RPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIKIWFQNRRTKWKRKYTSDVETLA 153
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 161.77 bits (408), Expect = 2.982e-46
Identity = 73/92 (79.35%), Postives = 85/92 (92.39%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHP 602
            KKPRKARTAF+DHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+  + PY+ YHP
Sbjct:  207 KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHP 296
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 161.77 bits (408), Expect = 2.982e-46
Identity = 73/92 (79.35%), Postives = 85/92 (92.39%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHP 602
            KKPRKARTAF+DHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+  + PY+ YHP
Sbjct:  207 KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHP 296
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 161.77 bits (408), Expect = 2.982e-46
Identity = 73/92 (79.35%), Postives = 85/92 (92.39%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHP 602
            KKPRKARTAF+DHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+  + PY+ YHP
Sbjct:  207 KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHP 296
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: barhl1a (BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-050417-212])

HSP 1 Score: 159.844 bits (403), Expect = 3.121e-46
Identity = 75/102 (73.53%), Postives = 91/102 (89.22%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMD 632
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D
Sbjct:  153 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLD 249
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: barhl1a (BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-050417-212])

HSP 1 Score: 159.844 bits (403), Expect = 3.291e-46
Identity = 75/102 (73.53%), Postives = 91/102 (89.22%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMD 632
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D
Sbjct:  153 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLD 249
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: BARHL2 (BarH like homeobox 2 [Source:NCBI gene;Acc:100493839])

HSP 1 Score: 163.696 bits (413), Expect = 7.525e-47
Identity = 76/103 (73.79%), Postives = 92/103 (89.32%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA 635
            KKPRKARTAF+DHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+  + PY+ YHP    ++S+MD+
Sbjct:  202 KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS---LLSSMDS 299
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: BARHL2 (BarH like homeobox 2 [Source:NCBI gene;Acc:100493839])

HSP 1 Score: 163.696 bits (413), Expect = 7.718e-47
Identity = 76/103 (73.79%), Postives = 92/103 (89.32%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA 635
            KKPRKARTAF+DHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+  + PY+ YHP    ++S+MD+
Sbjct:  209 KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS---LLSSMDS 306
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: pdlim7 (PDZ and LIM domain 7 [Source:Xenbase;Acc:XB-GENE-5860425])

HSP 1 Score: 159.073 bits (401), Expect = 1.734e-45
Identity = 75/102 (73.53%), Postives = 91/102 (89.22%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMD 632
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLD 272
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: pmp2 (peripheral myelin protein 2 [Source:Xenbase;Acc:XB-GENE-977969])

HSP 1 Score: 88.9669 bits (219), Expect = 4.830e-20
Identity = 42/80 (52.50%), Postives = 51/80 (63.75%), Query Frame = 3 
Query:  282 DDVSNCNQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVG 521
              V+NC          KPR+ARTAFT  QL  LE  F   +YLSV +R+ LA  L LT+TQVK W+QNRRTKWK+Q  +G
Sbjct:   93 PSVTNC----------KPRRARTAFTYEQLVALESRFRSSRYLSVCERLSLALTLHLTETQVKIWFQNRRTKWKKQQPIG 162
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: BARX2 (BARX homeobox 2 [Source:NCBI gene;Acc:100488405])

HSP 1 Score: 86.2705 bits (212), Expect = 9.748e-19
Identity = 40/65 (61.54%), Postives = 48/65 (73.85%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVG 521
            KKPR++RT FT+ QL  LEK F++QKYLS  DR++LA  L LT  QVKTWYQNRR KWK+    G
Sbjct:  133 KKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKIVLKG 197
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Barhl2 (BarH like homeobox 2 [Source:MGI Symbol;Acc:MGI:1859314])

HSP 1 Score: 163.696 bits (413), Expect = 9.557e-47
Identity = 75/103 (72.82%), Postives = 91/103 (88.35%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA 635
            KKPRKARTAF+DHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+  + PY+ YHP    ++ +MD+
Sbjct:  227 KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS---LLGSMDS 324
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Barhl1 (BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:1859288])

HSP 1 Score: 159.844 bits (403), Expect = 6.001e-46
Identity = 79/129 (61.24%), Postives = 99/129 (76.74%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA-----MLKQQQALSMCRNNPFLQQIL 698
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D      + +   A       P + +IL
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLDPGAALYLYRGPSAPPPALQRPLVPRIL 299
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Barhl1 (BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:1859288])

HSP 1 Score: 159.844 bits (403), Expect = 6.001e-46
Identity = 79/129 (61.24%), Postives = 99/129 (76.74%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA-----MLKQQQALSMCRNNPFLQQIL 698
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D      + +   A       P + +IL
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLDPGAALYLYRGPSAPPPALQRPLVPRIL 299
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Barhl1 (BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:1859288])

HSP 1 Score: 159.844 bits (403), Expect = 6.001e-46
Identity = 79/129 (61.24%), Postives = 99/129 (76.74%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA-----MLKQQQALSMCRNNPFLQQIL 698
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D      + +   A       P + +IL
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLDPGAALYLYRGPSAPPPALQRPLVPRIL 299
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Barx2 (BarH-like homeobox 2 [Source:MGI Symbol;Acc:MGI:109617])

HSP 1 Score: 87.4261 bits (215), Expect = 3.055e-19
Identity = 40/65 (61.54%), Postives = 48/65 (73.85%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVG 521
            KKPR++RT FT+ QL  LEK F++QKYLS  DR++LA  L LT  QVKTWYQNRR KWK+    G
Sbjct:  135 KKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKG 199
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8VIB5|BARH2_MOUSE (BarH-like 2 homeobox protein OS=Mus musculus OX=10090 GN=Barhl2 PE=2 SV=2)

HSP 1 Score: 163.696 bits (413), Expect = 6.685e-46
Identity = 75/103 (72.82%), Postives = 91/103 (88.35%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA 635
            KKPRKARTAF+DHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+  + PY+ YHP    ++ +MD+
Sbjct:  227 KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS---LLGSMDS 324
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9NY43|BARH2_HUMAN (BarH-like 2 homeobox protein OS=Homo sapiens OX=9606 GN=BARHL2 PE=1 SV=2)

HSP 1 Score: 163.696 bits (413), Expect = 7.451e-46
Identity = 75/104 (72.12%), Postives = 91/104 (87.50%), Query Frame = 3 
Query:  324 GKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA 635
             KKPRKARTAF+DHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY+ YHP    ++ +MD+
Sbjct:  229 AKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPYF-YHPS---LLGSMDS 327
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|O88181|BARH2_RAT (BarH-like 2 homeobox protein OS=Rattus norvegicus OX=10116 GN=Barhl2 PE=2 SV=1)

HSP 1 Score: 162.925 bits (411), Expect = 1.132e-45
Identity = 75/103 (72.82%), Postives = 91/103 (88.35%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA 635
            KKPRKARTAF+DHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+  + PY+ YHP    ++ +MD+
Sbjct:  227 KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS---LLGSMDS 324
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9BZE3|BARH1_HUMAN (BarH-like 1 homeobox protein OS=Homo sapiens OX=9606 GN=BARHL1 PE=2 SV=1)

HSP 1 Score: 160.614 bits (405), Expect = 2.295e-45
Identity = 79/129 (61.24%), Postives = 99/129 (76.74%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA-----MLKQQQALSMCRNNPFLQQIL 698
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D      + +   A       P + +IL
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLDPGAALYLYRGPSAPPPALQRPLVPRIL 299
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|P63156|BARH1_RAT (BarH-like 1 homeobox protein OS=Rattus norvegicus OX=10116 GN=Barhl1 PE=2 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 4.198e-45
Identity = 79/129 (61.24%), Postives = 99/129 (76.74%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDA-----MLKQQQALSMCRNNPFLQQIL 698
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D      + +   A       P + +IL
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLDPGAALYLYRGPSAPPPALQRPLVPRIL 299
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: K1QGS5 (BarH-like 1 homeobox protein (Fragment) OS=Crassostrea gigas OX=29159 GN=CGI_10009941 PE=4 SV=1)

HSP 1 Score: 197.593 bits (501), Expect = 2.008e-59
Identity = 101/150 (67.33%), Postives = 120/150 (80.00%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYW-TYHPEARVVISNMDAMLKQQQALSMCRNNPFLQQILATNPTIDKSINFLTSNSFPTSNIGS 773
            KKPRKARTAFTDHQLN LEK+FE+QKYLSVQDRMELA+KL LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGNFAAVQR+IQ+NPYW TYHP+A  +ISN+DAM  +    S+ +  P L ++L     I + IN ++    PT+++ S
Sbjct:    3 KKPRKARTAFTDHQLNSLEKSFERQKYLSVQDRMELASKLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRLIQSNPYWFTYHPQATSIISNIDAMYYRHNETSITQ-RPTLPRMLIHG--IQQHINHMS----PTNSLFS 145
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A210R3X0 (BarH-like 1 homeobox protein OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT03619 PE=4 SV=1)

HSP 1 Score: 198.364 bits (503), Expect = 4.321e-57
Identity = 100/153 (65.36%), Postives = 117/153 (76.47%), Query Frame = 3 
Query:  243 QESESTGSIDLGSDDVSNCNQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYW-TYHPEARVVISNMDAMLKQQQALSMCRNNPFLQQIL 698
            ++ +  GS D  +D V+     GL +  KK RKARTAFTDHQLN LEK FE+QKYLSVQDRMELAAKL LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN+AAVQR++QTNPYW TYHP+A  +ISN+DA+  +    SM    P L ++ 
Sbjct:  185 EDKKEDGSSDQQTDSVT-----GLMKP-KKARKARTAFTDHQLNSLEKTFERQKYLSVQDRMELAAKLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAVQRLLQTNPYWFTYHPQASGIISNIDALYYRHGESSMTPQRPTLPRMF 331
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A095AHB9 (BarH-like 2 homeobox protein OS=Schistosoma haematobium OX=6185 GN=MS3_01499 PE=4 SV=1)

HSP 1 Score: 189.119 bits (479), Expect = 1.809e-55
Identity = 83/109 (76.15%), Postives = 97/109 (88.99%), Query Frame = 3 
Query:  324 GKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDAMLKQQ 650
             KKPRK+RTAFTD QLNELEK F+ QKYLSVQDR+ELA +L LTDTQVKTWYQNRRTKWKRQT VG ELLAEAGNF AVQRI+QTNPYW YHP A+ +++NM+A++K++
Sbjct:    4 SKKPRKSRTAFTDLQLNELEKMFDHQKYLSVQDRIELAERLHLTDTQVKTWYQNRRTKWKRQTAVGFELLAEAGNFVAVQRILQTNPYWAYHPAAQTILANMEAIMKKK 112
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A1I8G487 (Homeobox domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 194.512 bits (493), Expect = 1.826e-55
Identity = 88/109 (80.73%), Postives = 98/109 (89.91%), Query Frame = 3 
Query:  318 QSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDAMLK 644
            Q  KKPRKARTAF+D+QLNELE+ FE+QKYLSVQDRMELAA+L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGNFAAVQRI+QTNPYW +HP A  VI+NMD + +
Sbjct:  161 QKAKKPRKARTAFSDNQLNELERAFERQKYLSVQDRMELAARLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAFHPGAHQVIANMDMICR 269
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A0L8FT91 (Homeobox domain-containing protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22008631mg PE=4 SV=1)

HSP 1 Score: 187.193 bits (474), Expect = 2.268e-55
Identity = 93/128 (72.66%), Postives = 106/128 (82.81%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYH-PEARVVISNMDAM-LKQQQALSMCRNNPFLQQILAT 704
            KKPRKARTAFTDHQL+ LEK+FE+QKYLSVQDRMELAAKL LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN+AAVQR+IQ NPYW+ H P+A  +ISN+DA+ L+     S+    P L + L T
Sbjct:    4 KKPRKARTAFTDHQLHCLEKSFERQKYLSVQDRMELAAKLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAVQRMIQANPYWSIHYPQAASIISNLDALYLRYSGTNSIQGQRPMLPRTLMT 131
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000055685.1 (barH-like 1 homeobox protein [Source:NCBI gene;Acc:103037310])

HSP 1 Score: 159.458 bits (402), Expect = 6.387e-46
Identity = 75/102 (73.53%), Postives = 91/102 (89.22%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMD 632
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D
Sbjct:  169 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLD 265
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: barhl2 (BarH like homeobox 2 [Source:NCBI gene;Acc:103036087])

HSP 1 Score: 155.221 bits (391), Expect = 7.618e-44
Identity = 71/92 (77.17%), Postives = 84/92 (91.30%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHP 602
            KKPRKARTAF+DHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAG+++A+QR+  + PY+ Y P
Sbjct:  212 KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGSYSALQRMFPS-PYF-YPP 301
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: barhl1a (BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-050417-212])

HSP 1 Score: 106.301 bits (264), Expect = 6.818e-27
Identity = 48/55 (87.27%), Postives = 51/55 (92.73%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRR 491
            KKPRKARTAFTDHQL ELE++F +QKYLSVQDRMELAA L LTDTQVKTWYQNRR
Sbjct:  161 KKPRKARTAFTDHQLAELERSFARQKYLSVQDRMELAASLNLTDTQVKTWYQNRR 215
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: barx2 (BARX homeobox 2 [Source:NCBI gene;Acc:103031514])

HSP 1 Score: 87.0409 bits (214), Expect = 3.110e-19
Identity = 40/65 (61.54%), Postives = 48/65 (73.85%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVG 521
            KKPR++RT FT+ QL  LEK F++QKYLS  DR++LA  L LT  QVKTWYQNRR KWK+    G
Sbjct:  131 KKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKG 195
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: barx1 (homeobox protein BarH-like 1 [Source:NCBI gene;Acc:103035562])

HSP 1 Score: 84.3445 bits (207), Expect = 1.034e-18
Identity = 42/82 (51.22%), Postives = 52/82 (63.41%), Query Frame = 3 
Query:  261 GSIDLGSDDVSNCNQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKR 506
            G ++ G D  S           KK R++RT FT+ QL  LEK FE+QKYLS  DR++LA  L L+  QVKTWYQNRR KWK+
Sbjct:  111 GKLEAGGDGASKT---------KKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 183
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 149.828 bits (377), Expect = 2.124e-45
Identity = 70/103 (67.96%), Postives = 82/103 (79.61%), Query Frame = 3 
Query:  324 GKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMD 632
             KKPRKARTAF+DHQL +LE++FE+QKYLSVQDRMELA+ L L+DTQVKTWYQNRRTKWKRQT VGLE LAEAG + A+QR+   NP +  H      +S MD
Sbjct:    2 AKKPRKARTAFSDHQLTQLERSFERQKYLSVQDRMELASSLSLSDTQVKTWYQNRRTKWKRQTAVGLEFLAEAGTYGALQRLFPNNPLYPPH------LSAMD 98
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 147.517 bits (371), Expect = 3.314e-44
Identity = 66/86 (76.74%), Postives = 76/86 (88.37%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNP 584
            KKPRKARTAF+DHQL +LE++FE+QKYLSVQDRMELA+ L L+DTQVKTWYQNRRTKWKRQT VGLE LAEAG + A+QR+   NP
Sbjct:    3 KKPRKARTAFSDHQLTQLERSFERQKYLSVQDRMELASSLSLSDTQVKTWYQNRRTKWKRQTAVGLEFLAEAGTYGALQRLFPNNP 88
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001480.1 (pep scaffold:Pmarinus_7.0:GL487501:66:2428:-1 gene:ENSPMAG00000001338.1 transcript:ENSPMAT00000001480.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 75.485 bits (184), Expect = 2.731e-17
Identity = 34/58 (58.62%), Postives = 45/58 (77.59%), Query Frame = 3 
Query:  324 GKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTK 497
            G + RKART FTD QL+ LE+ F +Q+YLS  +R++LA  L L++TQVKTW+QNRR K
Sbjct:    3 GVRRRKARTVFTDSQLSGLERRFVRQRYLSTPERVDLATALGLSETQVKTWFQNRRMK 60
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: tlx1 (T cell leukemia homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-021021-2])

HSP 1 Score: 78.1814 bits (191), Expect = 7.283e-17
Identity = 34/58 (58.62%), Postives = 44/58 (75.86%), Query Frame = 3 
Query:  330 KPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWK 503
            K +K RT+FT  Q+ ELEK F +QKYL+  +R  LA  L++TD QVKTW+QNRRTKW+
Sbjct:  229 KRKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWR 286
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001141.1 (pep scaffold:Pmarinus_7.0:GL478075:36995:38394:-1 gene:ENSPMAG00000001023.1 transcript:ENSPMAT00000001141.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.4034 bits (176), Expect = 2.239e-16
Identity = 34/59 (57.63%), Postives = 45/59 (76.27%), Query Frame = 3 
Query:  330 KPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKR 506
            K R+ RTAF+  QL ELE++F +Q+YLS   R ++A+ L LT+TQVK W+QNRR KWKR
Sbjct:    2 KCRRPRTAFSSQQLLELERHFSRQRYLSRPQRFQVASALMLTETQVKIWFQNRRMKWKR 60
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO43402 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYQ0])

HSP 1 Score: 80.8777 bits (198), Expect = 1.755e-19
Identity = 36/60 (60.00%), Postives = 48/60 (80.00%), Query Frame = 3 
Query:  330 KPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQ 509
            K R+ RTAFT  QL  LE+ F+++KYL++ +R ELA  + L+DTQVKTW+QNRRTKWK+Q
Sbjct:   10 KSRRKRTAFTSSQLKYLEEKFQEKKYLTISERNELAKSMYLSDTQVKTWFQNRRTKWKKQ 69
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO38891 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBL6])

HSP 1 Score: 78.9518 bits (193), Expect = 8.529e-19
Identity = 36/64 (56.25%), Postives = 49/64 (76.56%), Query Frame = 3 
Query:  336 RKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLE 527
            R+ RTAFT  QL  LE+ F+++KYL++ +R  LA  + LT+TQVKTW+QNRRTKWK+Q +  LE
Sbjct:    2 RRRRTAFTSSQLKSLEEKFQEKKYLTISERNSLAKSMHLTNTQVKTWFQNRRTKWKKQMSPDLE 65
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO34127 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQ94])

HSP 1 Score: 78.5666 bits (192), Expect = 8.624e-19
Identity = 38/58 (65.52%), Postives = 46/58 (79.31%), Query Frame = 3 
Query:  336 RKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQ 509
            +K RTAFT+ Q++ELEK F+ QKYL  ++R ELA  L LTDTQVKTW+QNRR K KRQ
Sbjct:    2 KKPRTAFTESQISELEKRFQSQKYLGSKERSELAGTLGLTDTQVKTWFQNRRMKLKRQ 59
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: NK-1 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI80])

HSP 1 Score: 83.5741 bits (205), Expect = 1.842e-18
Identity = 40/69 (57.97%), Postives = 51/69 (73.91%), Query Frame = 3 
Query:  330 KPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLA 536
            KPR+ARTAFT  QL  LE  F+  +YLSV +R+ LA  L LT+TQVK W+QNRRTKWK+Q   G+++ A
Sbjct:  156 KPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLALSLGLTETQVKIWFQNRRTKWKKQNP-GMDVTA 223
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO32495 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUX2])

HSP 1 Score: 77.411 bits (189), Expect = 2.550e-18
Identity = 35/58 (60.34%), Postives = 46/58 (79.31%), Query Frame = 3 
Query:  336 RKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQ 509
            ++ RTAFT+ Q+ +LE  F++ KYLSV  RMELA  L LT+TQ+K W+QNRRTKWKR+
Sbjct:    2 KRPRTAFTNEQIKDLEAEFQKSKYLSVSRRMELANSLSLTETQIKIWFQNRRTKWKRK 59
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: barhl2 (BarH like homeobox 2 [Source:NCBI gene;Acc:101174414])

HSP 1 Score: 163.31 bits (412), Expect = 6.198e-47
Identity = 74/92 (80.43%), Postives = 85/92 (92.39%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHP 602
            KKPRKARTAFTDHQLN+LE++FE+QKYLSVQDRM+LAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+  + PY+ YHP
Sbjct:  204 KKPRKARTAFTDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHP 293
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000038356.1 (barH-like 1 homeobox protein [Source:NCBI gene;Acc:100049373])

HSP 1 Score: 160.229 bits (404), Expect = 4.053e-46
Identity = 75/102 (73.53%), Postives = 91/102 (89.22%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMD 632
            KKPRKARTAFTDHQL +LE++FE+QKYLSVQDRMELAA L LTDTQVKTWYQNRRTKWKRQT VGLELLAEAGN++A+QR+   +PY  ++P++  ++SN+D
Sbjct:  171 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYPQS--LVSNLD 267
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: barhl1a (BarH like homeobox 1 [Source:NCBI gene;Acc:101158364])

HSP 1 Score: 123.25 bits (308), Expect = 9.403e-33
Identity = 67/126 (53.17%), Postives = 86/126 (68.25%), Query Frame = 3 
Query:  168 DENQQNKLSILALNNNLKNQWTDDDQESESTGSIDLGSDDVSNCNQRGLSQSG---KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLA 536
            DE+  +K+S+   ++N K    + D+ S+           VS    R     G   KKPRKARTAF+D QL+ LE++F++QKYLSVQDR+ELAA L+L+DTQVKTWYQNRRTKWKRQ+  GLELLA
Sbjct:   93 DEDYWDKMSVSPASDN-KGAGLNSDEWSQH----------VSPEGGRSFDPVGVRLKKPRKARTAFSDQQLSRLERSFQKQKYLSVQDRIELAASLQLSDTQVKTWYQNRRTKWKRQSAAGLELLA 207
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: nkx1.2la (NK1 homeobox 2 [Source:NCBI gene;Acc:101168069])

HSP 1 Score: 88.1965 bits (217), Expect = 8.461e-20
Identity = 46/88 (52.27%), Postives = 58/88 (65.91%), Query Frame = 3 
Query:  246 ESESTGSIDLGSDDVSNCNQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQ 509
            E+ES  +I   + D S   +R   Q+  KPR+ARTAFT  QL  LE  F   +YLSV +R+ LA  L LT+TQVK W+QNRRTKWK+Q
Sbjct:  103 EAESDAAI--ATQDRSTHKRRRSDQACAKPRRARTAFTYEQLVALENKFRTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ 188
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: barx2 (BARX homeobox 2 [Source:NCBI gene;Acc:101170038])

HSP 1 Score: 87.4261 bits (215), Expect = 2.312e-19
Identity = 40/65 (61.54%), Postives = 48/65 (73.85%), Query Frame = 3 
Query:  327 KKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVG 521
            KKPR++RT FT+ QL  LEK F++QKYLS  DR++LA  L LT  QVKTWYQNRR KWK+    G
Sbjct:  136 KKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKG 200
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000074896.1 (SMESG000074896.1)

HSP 1 Score: 601.282 bits (1549), Expect = 0.000e+0
Identity = 293/294 (99.66%), Postives = 294/294 (100.00%), Query Frame = 3 
Query:   69 MSSISKFENTKENPKNQVNYQKSNGSFMISELIDENQQNKLSILALNNNLKNQWTDDDQESESTGSIDLGSDDVSNCNQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDAMLKQQQALSMCRNNPFLQQILATNPTIDKSINFLTSNSFPTSNIGSSEIGKLSSPPTSDSSNELVSTNNLISTQKLPQFSSANIQPDSKLFSAFHRLLNVSKPLV 950
            MSSISKFENTKENPKNQVNYQKSNGSFMISELIDENQQNKLSILALNNNLKNQWTDDDQESESTGSIDLGSDDVSNCN+RGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDAMLKQQQALSMCRNNPFLQQILATNPTIDKSINFLTSNSFPTSNIGSSEIGKLSSPPTSDSSNELVSTNNLISTQKLPQFSSANIQPDSKLFSAFHRLLNVSKPLV
Sbjct:    1 MSSISKFENTKENPKNQVNYQKSNGSFMISELIDENQQNKLSILALNNNLKNQWTDDDQESESTGSIDLGSDDVSNCNRRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDAMLKQQQALSMCRNNPFLQQILATNPTIDKSINFLTSNSFPTSNIGSSEIGKLSSPPTSDSSNELVSTNNLISTQKLPQFSSANIQPDSKLFSAFHRLLNVSKPLV 294
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000030375.1 (SMESG000030375.1)

HSP 1 Score: 196.823 bits (499), Expect = 5.367e-61
Identity = 93/127 (73.23%), Postives = 106/127 (83.46%), Query Frame = 3 
Query:  273 LGSDDVSNCNQRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDAMLKQQQ 653
            LGSD  S+   +      KKPRKARTAFTD QLNELE+NF++QKYLSVQDRMELA +LRL+DTQVKTWYQNRRTKWKRQT VGLELLAEAGNFAAVQRI+QTNPYW YHP  + VI+NM+ + +Q Q
Sbjct:  120 LGSDSQSHDRSKS-----KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIARQHQ 241
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000022963.1 (SMESG000022963.1)

HSP 1 Score: 126.331 bits (316), Expect = 1.234e-34
Identity = 62/112 (55.36%), Postives = 80/112 (71.43%), Query Frame = 3 
Query:  315 SQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQ---TNPYWTYHPEARVVISNMDAML 641
            S S K+PRKARTAFT+ QL ELEK+F++ KYLSVQDR+ELA  L LTDTQVKTWYQNRRTKWKRQT+ G++LL E  N   ++R I     + +W +       +SN+ ++ 
Sbjct:   60 SFSEKRPRKARTAFTEKQLCELEKSFDKHKYLSVQDRLELANYLELTDTQVKTWYQNRRTKWKRQTSTGVDLLTEGSNVTDLRRSIHYPNNSKFWNWVSNNSASLSNIPSIF 171
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000017206.1 (SMESG000017206.1)

HSP 1 Score: 80.4925 bits (197), Expect = 1.229e-17
Identity = 45/104 (43.27%), Postives = 63/104 (60.58%), Query Frame = 3 
Query:  330 KPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGN--FAAVQRII--QTNPYWTYHPEARVVISNM 629
            K +K RT+F   Q+ ELE+ F +QKYL+  +R +LA  L +TD+QVKTW+QNRRTKW+RQT+   E   +A +     +Q  I    NP + Y       ISN+
Sbjct:   77 KRKKPRTSFNRQQIMELERRFHRQKYLASSERCDLAKDLDMTDSQVKTWFQNRRTKWRRQTSEEREAERQAASRYLLTLQNEINQSNNPSFNYTSSTLSAISNL 180
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000033607.1 (SMESG000033607.1)

HSP 1 Score: 82.8037 bits (203), Expect = 1.298e-17
Identity = 36/57 (63.16%), Postives = 47/57 (82.46%), Query Frame = 3 
Query:  336 RKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKR 506
            RKART F+D QLN LEK FE Q+YLS  +R+ELA +L L+++QVKTW+QNRR K+K+
Sbjct:  201 RKARTVFSDQQLNGLEKRFESQRYLSTPERIELANQLNLSESQVKTWFQNRRMKYKK 257
The following BLAST results are available for this feature:
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BARHL21.552e-4672.12BarH like homeobox 2 [Source:HGNC Symbol;Acc:HGNC:... [more]
BARHL14.779e-4661.24BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
BARHL14.779e-4661.24BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
BARX23.504e-1961.54BARX homeobox 2 [Source:HGNC Symbol;Acc:HGNC:956][more]
GBX13.953e-1836.18gastrulation brain homeobox 1 [Source:HGNC Symbol;... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ceh-312.399e-4350.29Homeobox protein ceh-31 [Source:UniProtKB/Swiss-P... [more]
ceh-303.669e-4167.01Homeobox protein ceh-30 [Source:UniProtKB/Swiss-P... [more]
ceh-303.669e-4167.01Homeobox protein ceh-30 [Source:UniProtKB/Swiss-P... [more]
ceh-91.245e-1762.71Homeobox protein ceh-9 [Source:UniProtKB/Swiss-Pr... [more]
ceh-13.464e-1748.24Homeobox protein ceh-1 [Source:UniProtKB/Swiss-Pr... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
B-H13.395e-4258.33gene:FBgn0011758 transcript:FBtr0074430[more]
B-H28.914e-4276.60gene:FBgn0004854 transcript:FBtr0334458[more]
B-H22.041e-4076.60gene:FBgn0004854 transcript:FBtr0074429[more]
CG110857.644e-2464.86gene:FBgn0030408 transcript:FBtr0073656[more]
lms6.555e-2049.00gene:FBgn0034520 transcript:FBtr0342702[more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
barhl22.982e-4679.35BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
barhl22.982e-4679.35BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
barhl22.982e-4679.35BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
barhl1a3.121e-4673.53BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-05... [more]
barhl1a3.291e-4673.53BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-05... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BARHL27.525e-4773.79BarH like homeobox 2 [Source:NCBI gene;Acc:1004938... [more]
BARHL27.718e-4773.79BarH like homeobox 2 [Source:NCBI gene;Acc:1004938... [more]
pdlim71.734e-4573.53PDZ and LIM domain 7 [Source:Xenbase;Acc:XB-GENE-5... [more]
pmp24.830e-2052.50peripheral myelin protein 2 [Source:Xenbase;Acc:XB... [more]
BARX29.748e-1961.54BARX homeobox 2 [Source:NCBI gene;Acc:100488405][more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Barhl29.557e-4772.82BarH like homeobox 2 [Source:MGI Symbol;Acc:MGI:18... [more]
Barhl16.001e-4661.24BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:18... [more]
Barhl16.001e-4661.24BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:18... [more]
Barhl16.001e-4661.24BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:18... [more]
Barx23.055e-1961.54BarH-like homeobox 2 [Source:MGI Symbol;Acc:MGI:10... [more]
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BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8VIB5|BARH2_MOUSE6.685e-4672.82BarH-like 2 homeobox protein OS=Mus musculus OX=10... [more]
sp|Q9NY43|BARH2_HUMAN7.451e-4672.12BarH-like 2 homeobox protein OS=Homo sapiens OX=96... [more]
sp|O88181|BARH2_RAT1.132e-4572.82BarH-like 2 homeobox protein OS=Rattus norvegicus ... [more]
sp|Q9BZE3|BARH1_HUMAN2.295e-4561.24BarH-like 1 homeobox protein OS=Homo sapiens OX=96... [more]
sp|P63156|BARH1_RAT4.198e-4561.24BarH-like 1 homeobox protein OS=Rattus norvegicus ... [more]
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BLAST of Homeobox domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
K1QGS52.008e-5967.33BarH-like 1 homeobox protein (Fragment) OS=Crassos... [more]
A0A210R3X04.321e-5765.36BarH-like 1 homeobox protein OS=Mizuhopecten yesso... [more]
A0A095AHB91.809e-5576.15BarH-like 2 homeobox protein OS=Schistosoma haemat... [more]
A0A1I8G4871.826e-5580.73Homeobox domain-containing protein OS=Macrostomum ... [more]
A0A0L8FT912.268e-5572.66Homeobox domain-containing protein OS=Octopus bima... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000055685.16.387e-4673.53barH-like 1 homeobox protein [Source:NCBI gene;Acc... [more]
barhl27.618e-4477.17BarH like homeobox 2 [Source:NCBI gene;Acc:1030360... [more]
barhl1a6.818e-2787.27BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-05... [more]
barx23.110e-1961.54BARX homeobox 2 [Source:NCBI gene;Acc:103031514][more]
barx11.034e-1851.22homeobox protein BarH-like 1 [Source:NCBI gene;Acc... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
barhl22.124e-4567.96BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
barhl23.314e-4476.74BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
ENSPMAT00000001480.12.731e-1758.62pep scaffold:Pmarinus_7.0:GL487501:66:2428:-1 gene... [more]
tlx17.283e-1758.62T cell leukemia homeobox 1 [Source:ZFIN;Acc:ZDB-GE... [more]
ENSPMAT00000001141.12.239e-1657.63pep scaffold:Pmarinus_7.0:GL478075:36995:38394:-1 ... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO434021.755e-1960.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO388918.529e-1956.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO341278.624e-1965.52Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
NK-11.842e-1857.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO324952.550e-1860.34Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
barhl26.198e-4780.43BarH like homeobox 2 [Source:NCBI gene;Acc:1011744... [more]
ENSORLT00000038356.14.053e-4673.53barH-like 1 homeobox protein [Source:NCBI gene;Acc... [more]
barhl1a9.403e-3353.17BarH like homeobox 1 [Source:NCBI gene;Acc:1011583... [more]
nkx1.2la8.461e-2052.27NK1 homeobox 2 [Source:NCBI gene;Acc:101168069][more]
barx22.312e-1961.54BARX homeobox 2 [Source:NCBI gene;Acc:101170038][more]
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BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000074896.10.000e+099.66SMESG000074896.1[more]
SMESG000030375.15.367e-6173.23SMESG000030375.1[more]
SMESG000022963.11.234e-3455.36SMESG000022963.1[more]
SMESG000017206.11.229e-1743.27SMESG000017206.1[more]
SMESG000033607.11.298e-1763.16SMESG000033607.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005064 ID=SMED30005064|Name=Homeobox domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1019bp
TACAATTAATATTCTACTTAACACAATAATCGTCCATTTAACTATTATTA
TCATCATTTTTGAAAGTTATGAGTTCAATCTCAAAATTTGAAAATACAAA
AGAAAACCCCAAAAATCAAGTGAATTATCAAAAATCGAATGGATCGTTTA
TGATTAGTGAATTGATTGATGAAAATCAACAAAATAAATTGAGCATTTTG
GCGTTAAATAACAATTTGAAAAATCAGTGGACAGATGACGATCAAGAATC
CGAGTCCACCGGGTCTATAGATTTGGGTTCTGACGATGTTTCCAACTGCA
ATCAAAGAGGATTATCGCAATCTGGAAAGAAACCGAGAAAAGCTCGAACA
GCGTTTACGGATCATCAATTGAATGAGTTGGAAAAAAATTTCGAACAACA
AAAATATTTGAGTGTTCAAGATCGAATGGAACTAGCAGCGAAACTGAGAC
TAACTGATACTCAAGTGAAAACCTGGTACCAAAACCGAAGAACTAAATGG
AAACGCCAAACAACTGTCGGATTGGAATTATTAGCGGAAGCTGGGAATTT
TGCTGCAGTCCAAAGAATCATTCAGACTAATCCTTATTGGACGTATCATC
CGGAAGCGAGAGTAGTTATTTCGAATATGGATGCAATGTTGAAACAACAA
CAGGCGCTTAGTATGTGCCGAAACAATCCATTTCTTCAACAAATTCTTGC
CACAAATCCTACAATCGACAAATCCATAAACTTTTTAACTTCAAATTCTT
TTCCTACTTCCAATATCGGTTCGTCGGAAATCGGAAAGTTGTCCTCTCCA
CCAACATCGGATTCATCAAACGAGCTGGTTTCGACAAACAATTTAATATC
AACTCAAAAATTGCCACAATTTTCTTCAGCTAATATACAGCCAGATTCAA
AATTATTTTCAGCCTTCCATCGCCTGTTGAACGTTTCAAAACCCTTGGTA
TAGAAGGTTGACAGGTGTTTGTTGAAAAGAATTGCGCTAAGATTTAGTTA
TGTAAATATGAATATGGTC
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protein sequence of SMED30005064-orf-1

>SMED30005064-orf-1 ID=SMED30005064-orf-1|Name=SMED30005064-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=295bp
MSSISKFENTKENPKNQVNYQKSNGSFMISELIDENQQNKLSILALNNNL
KNQWTDDDQESESTGSIDLGSDDVSNCNQRGLSQSGKKPRKARTAFTDHQ
LNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTV
GLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDAMLKQQQALSMC
RNNPFLQQILATNPTIDKSINFLTSNSFPTSNIGSSEIGKLSSPPTSDSS
NELVSTNNLISTQKLPQFSSANIQPDSKLFSAFHRLLNVSKPLV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000043dorsal ventral margin of the whole animal
PLANA:0000420parapharyngeal region
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR020479Homeobox_metazoa
IPR001356Homeobox_dom
IPR009057Homeobox-like_sf
IPR017970Homeobox_CS
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0043565sequence-specific DNA binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR020479Homeobox domain, metazoaPRINTSPR00024HOMEOBOXcoord: 126..136
score: 57.09
coord: 136..145
score: 69.89
coord: 111..122
score: 39.77
IPR001356Homeobox domainSMARTSM00389HOX_1coord: 89..151
e-value: 1.9E-25
score: 100.6
IPR001356Homeobox domainPFAMPF00046Homeodomaincoord: 90..146
e-value: 6.8E-22
score: 77.1
IPR001356Homeobox domainPROSITEPS50071HOMEOBOX_2coord: 87..147
score: 21.054
IPR001356Homeobox domainCDDcd00086homeodomaincoord: 90..147
e-value: 1.76273E-21
score: 83.4468
NoneNo IPR availableGENE3DG3DSA:1.10.10.60coord: 76..153
e-value: 3.0E-26
score: 92.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 55..93
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 64..83
NoneNo IPR availablePANTHERPTHR24330:SF8BARH-LIKE 1 HOMEOBOX PROTEINcoord: 83..189
NoneNo IPR availablePANTHERPTHR24330FAMILY NOT NAMEDcoord: 83..189
IPR017970Homeobox, conserved sitePROSITEPS00027HOMEOBOX_1coord: 122..145
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 79..147