Serine/threonine kinase
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30005039 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of Serine/threonine kinase vs. Ensembl Human
Match: SPEG (striated muscle enriched protein kinase [Source:HGNC Symbol;Acc:HGNC:16901]) HSP 1 Score: 134.035 bits (336), Expect = 6.644e-30 Identity = 133/603 (22.06%), Postives = 270/603 (44.78%), Query Frame = 2 Query: 8708 REITLSWSPPRISPDLYIPFTVDVECRPVNYSYS------DEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITW-TFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGEYCALDEVQDPIQ--SFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQI-NIGD--------VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFF--EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIM--TGKYNEILKLCGFSNA---VPKE----DFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYI 10393 R +TL+W+PPR ++D+ P + +Y+ + W+ T +++ L + + R++ T KPS + ++ ++ PT E+A + +K + ++ Q A + T + ++ W + A ++ Y++ + I + D G + Q S L ++AP + + + + E +V ++ +P P+++W ++ + SS+ + + E+ E SL++ DGG Y+ A+N G K L V H + ++++ +G+ ++D Y +++ +G++S + ++E+S+ +EF KF + R E + + + H ++ +A + LV++ E L L E I + CES++R + Q+++ + YLH+ V HLD+KPEN+++ + +++C F NA P E +G T F APE++ P+ +D+W +G++ FLCL G E D+ + E + ++S A F+ K +L++ R T+ ++L H WF + D++ Sbjct: 1297 RMVTLTWNPPR---------SLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEH--GPTLEEAPAMLDKPDI---VYVVEGQPASVTVT--FNHVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENE---CSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV--HSAQTAMEVEGVGEDEDHRGRRLSDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHDCVLYFHEAFER-RRGLVIVTE-LCTEELLERIARKPTVCESEIRAYMRQVLEGIHYLHQSHVLHLDVKPENLLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQYG-------TPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIK-VLVQDRLRPTAEETLEHPWFKTQAKGAEVSTDHL 1868 HSP 2 Score: 115.546 bits (288), Expect = 2.121e-24 Identity = 79/270 (29.26%), Postives = 124/270 (45.93%), Query Frame = 2 Query: 9599 INIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSR--RHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH---------------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 + G Y +++ A+G + + E +T F+ K G R E++ ++ + H I+ + +A P +YLVLI E L ++ + E V + QL+Q + YLH H V HLDIKP+N+++ + LK+ F +A P R H T F APE++KGEPI +D+W G+LT++ L G + F+ QLY S SA +F+RK L + R + D L+H W Sbjct: 2957 LRQGPPQKPYTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERIMSLHEAYITP-RYLVLIAESCGNRELLCGLSDRFRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLLA--PDNALKIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAFQLYPN-----TSQSATLFLRKVLSVHPWSRPSLQDCLAHPWL 3218 HSP 3 Score: 55.0694 bits (131), Expect = 4.146e-6 Identity = 67/265 (25.28%), Postives = 109/265 (41.13%), Query Frame = 2 Query: 11528 EYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLE---NCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISST 12313 EY V RT E I + + +Y +L E C GNR LL L R YSE V T + QLL + +LH ++V+H +I+P +L++ + + I G N Q + + + F APE +DIW G+L++++L+ + P E +++ + L P+T S+S+ F+ L P R + LAH W QD + ++ QT++ T Sbjct: 3010 EYEVLRTLHHERIMSLHEAYITPRYL---VLIAESC----GNR----------ELLCGLSDRFRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLLA--PDNALKIVDFGSAQPYNPQALRPLGHRTGTLE-----FMAPEMVKGEPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAFQL-YPNT-------------SQSATLFLRKVLSVHPWSRPSLQDCLAHPWL-QD-AYLMKLRRQTLTFT 3234 HSP 4 Score: 55.0694 bits (131), Expect = 4.662e-6 Identity = 36/120 (30.00%), Postives = 57/120 (47.50%), Query Frame = 2 Query: 6074 APLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAE 6433 AP+F L+++ + ++ L C + +P P++ W KDG L S+ R+ + E TL++ EA D+G Y TN LG T A + V P S S P +P+ + E Sbjct: 721 APVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSE---GRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTV---RPGGSTS------PFSSPITSDE 828
BLAST of Serine/threonine kinase vs. Ensembl Human
Match: DAPK2 (death associated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:2675]) HSP 1 Score: 119.013 bits (297), Expect = 2.068e-27 Identity = 85/281 (30.25%), Postives = 138/281 (49.11%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFE-----INNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQL-------------YNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAAL 10384 V D Y ++L G ++ + EKST +E+ KF + + G+ R E + ++ + H N++ + D +VLI E + G L +++ Q E + I Q++ V+YLH ++ H D+KPENI++ K I +KL F A ED +++ T F APE++ EP+ +DMWSIG++T++ L G F GD ++E+ S A FIRK L+ +T +RLT ++L H W I P +N A + Sbjct: 19 VEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTD-VVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSG--ASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPW-ITPVDNQQAMV 295 HSP 2 Score: 63.5438 bits (153), Expect = 4.213e-9 Identity = 39/139 (28.06%), Postives = 67/139 (48.20%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRY-----ESDIWSLGILSFLLLATQLPAIEDACSDS 12070 E V GG L L + SE + I+Q+L + +LH+ + H +++P I++ + IKLI G E E K +IF PE+ I Y E+D+WS+G+++++LL+ P + D ++ Sbjct: 104 ELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDF------GLAHEIEDGVEFK-NIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQET 235
BLAST of Serine/threonine kinase vs. Ensembl Human
Match: DAPK2 (death associated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:2675]) HSP 1 Score: 119.013 bits (297), Expect = 2.068e-27 Identity = 85/281 (30.25%), Postives = 138/281 (49.11%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFE-----INNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQL-------------YNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAAL 10384 V D Y ++L G ++ + EKST +E+ KF + + G+ R E + ++ + H N++ + D +VLI E + G L +++ Q E + I Q++ V+YLH ++ H D+KPENI++ K I +KL F A ED +++ T F APE++ EP+ +DMWSIG++T++ L G F GD ++E+ S A FIRK L+ +T +RLT ++L H W I P +N A + Sbjct: 19 VEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTD-VVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSG--ASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPW-ITPVDNQQAMV 295 HSP 2 Score: 63.5438 bits (153), Expect = 4.213e-9 Identity = 39/139 (28.06%), Postives = 67/139 (48.20%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRY-----ESDIWSLGILSFLLLATQLPAIEDACSDS 12070 E V GG L L + SE + I+Q+L + +LH+ + H +++P I++ + IKLI G E E K +IF PE+ I Y E+D+WS+G+++++LL+ P + D ++ Sbjct: 104 ELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDF------GLAHEIEDGVEFK-NIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQET 235
BLAST of Serine/threonine kinase vs. Ensembl Human
Match: DAPK2 (death associated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:2675]) HSP 1 Score: 117.472 bits (293), Expect = 4.191e-26 Identity = 82/276 (29.71%), Postives = 133/276 (48.19%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFE-----INNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQL-------------YNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNN 10369 V D Y ++L G ++ + EKST +E+ KF + + G+ R E + ++ + H N++ + D +VLI E + G L +++ Q E + I Q++ V+YLH ++ H D+KPENI++ K I +KL F A ED +++ T F APE++ EP+ +DMWSIG++T++ L G F GD ++E+ S A FIRK L+ +T +RLT ++L H W G Sbjct: 19 VEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTD-VVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSG--ASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITSKGEG 291 HSP 2 Score: 62.7734 bits (151), Expect = 1.007e-8 Identity = 39/139 (28.06%), Postives = 67/139 (48.20%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRY-----ESDIWSLGILSFLLLATQLPAIEDACSDS 12070 E V GG L L + SE + I+Q+L + +LH+ + H +++P I++ + IKLI G E E K +IF PE+ I Y E+D+WS+G+++++LL+ P + D ++ Sbjct: 104 ELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDF------GLAHEIEDGVEFK-NIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQET 235
BLAST of Serine/threonine kinase vs. Ensembl Human
Match: DAPK2 (death associated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:2675]) HSP 1 Score: 117.472 bits (293), Expect = 4.191e-26 Identity = 82/276 (29.71%), Postives = 133/276 (48.19%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFE-----INNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQL-------------YNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNN 10369 V D Y ++L G ++ + EKST +E+ KF + + G+ R E + ++ + H N++ + D +VLI E + G L +++ Q E + I Q++ V+YLH ++ H D+KPENI++ K I +KL F A ED +++ T F APE++ EP+ +DMWSIG++T++ L G F GD ++E+ S A FIRK L+ +T +RLT ++L H W G Sbjct: 19 VEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTD-VVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSG--ASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITSKGEG 291 HSP 2 Score: 62.7734 bits (151), Expect = 1.007e-8 Identity = 39/139 (28.06%), Postives = 67/139 (48.20%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRY-----ESDIWSLGILSFLLLATQLPAIEDACSDS 12070 E V GG L L + SE + I+Q+L + +LH+ + H +++P I++ + IKLI G E E K +IF PE+ I Y E+D+WS+G+++++LL+ P + D ++ Sbjct: 104 ELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDF------GLAHEIEDGVEFK-NIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQET 235
BLAST of Serine/threonine kinase vs. Ensembl Celegans
Match: unc-89 (Muscle M-line assembly protein unc-89 [Source:UniProtKB/Swiss-Prot;Acc:O01761]) HSP 1 Score: 137.117 bits (344), Expect = 3.377e-31 Identity = 157/617 (25.45%), Postives = 269/617 (43.60%), Query Frame = 2 Query: 8714 ITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGI-------------GKPSMVIKKIRRSDN---LNSPTTEKA--MMLQEKHCLAVPMFC--------CLSQKAELKFTKLMEYKLDKITWTFNNAKVDVND--ERYKIFSAETYGIYFIIKNLEEDDFGEY-C-ALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTY--SLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPE-------KKSVQINIGDVNDRYYTMKK----LAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIY-----EKLQGLS-LAEYITQLSHWC----ESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHM--GL------TSP-FSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ--LYNEDS----NDAISN---SACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +TLSW P + +P Y T +E R + E+ WS+ + NI + + +L+ +YQ R+ +GI P V RR++ L P EKA M E++ A P F C + + I W F +D + + K+++ I +++ G+Y C A ++ D Q+ ++ + P + L N + + + + V++D +P PE+ W + W+ I S R +D G Y SL+I+ + D G YS A N G A + V+A + ++ V I V + Y +K A+G+ R V EK+T EF+ + I++ + + ++ H IV++ + D+ L L+ + GLS LA +++ E+ VR+ + QL+ A+ ++H+ R+ HLD++PE I++ ++ LKL DFG R + GL SP F +PE+++ P+ +DMWS G+LT++ L G + + D L N DS + + N A F++K L RLT ++L H W Sbjct: 5652 LTLSWIPTKRAPPRYPQVTYVIEIREL-----PEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAENIYGISDPSPASPPSRLMAPPQPVFD--RRTNKVIPLLDPYAEKALDMRYSEQYACA-PWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVGQYQCFAKNDYGDAQQNIMVDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQD---GPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTVTVEAEGDYNDVELPRRRVTIESRRVRELYEISEKDEKLAAEGAPFR---VKEKATGREFLAQLRPIDDALMRHVDIH--NSLDHPGIVQMHRVLR--DEKLALVVFDNANSTIDGLSSLAHPGVEIAEPKGVNRETCVRVFVRQLLLALKHMHDLRIAHLDLRPETILL---QDDKLKLA---------DFGQARRLLRGLITGEIKGSPEFVSPEIVRSYPLTLATDMWSTGVLTYVLLTGLSPFHGDNDNETLANVDSCQFDSSPLGNFSYDAGDFVKKLLTEIPVSRLTVDEALDHPWI 6238 HSP 2 Score: 98.5969 bits (244), Expect = 1.219e-19 Identity = 170/765 (22.22%), Postives = 301/765 (39.35%), Query Frame = 2 Query: 4283 GFSKKDIKWKVLEDDLKQDKILQE---KRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEM-KSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDD--IDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFI----------DLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDE-KLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INESSVDILV---KVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSC--DNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCI-----------------------APLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKI-LDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVT-DSEPKESDSSRIIVKPLCAPVLT 6427 G S D++W K DK + E + + + L++ D+G Y + +N +E V ++ + E ++IN+ T+ ++ SV W +G+ ++ S +++ ++ +G + + I++ G Y C N G + T V+N+ +E+ E L V + +W KDD I N + F+LT A D G+Y + G+ L +F + + I T + L + E + D K +I V N ++W ++D P +DN I L I+ + E G+Y C TNE E + + V+ E++ +P+ + L E + + EL V RV K W KD + + + + + L+++D D G Y+ + N++ D V K+ KQT E K L I +PL++ F E +TV E +V + + I FF+N++ E + +Q D LTI A ++ G Y + N G ++ L + +++ E + + AP F + L+ + K+ L C++ +P+PKI WTK+G+ ++ ++ RV+ + TL D+G Y C N G TE IIVT + PK + ++P+ V+T Sbjct: 2573 GGSAPDVEW------FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKA-SNPAGTAESSAEAEVTQSLEKPTFVR---ELVTTEVKINETATLSVTVKGVPDP-SVEWLKDGQPVQTDSSHVIAKVEGSGSYS-ITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFT--QKLRPLEVREQETL--DLKVTVIGTPVPN-----VEWFKDDKPIN----IDNSHIFAKDEGSGHHTLTIKQAR-GEDVGVYTCKATNEAGEAKTTANMAVQ---EEIEAPLFVQGLKPYEVE----QGKPAELVV--RVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKPLFI----EPLKETFAV-EGDTVVLECKVNKE-SHPQIKFFKNDQ-PVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVE---MSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVT 3292 HSP 3 Score: 93.9745 bits (232), Expect = 3.494e-18 Identity = 131/612 (21.41%), Postives = 246/612 (40.20%), Query Frame = 2 Query: 10619 TPNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILN-ATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSP-----YLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRN-----IHSLKQALIFNRKWMLTSRQSNHFNDL--------------HDLIKDIS--SDDI-------------RMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFV-GTVKEQESLTTHKPSIFKAPEYRY-ESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNT--NTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPL 12319 P+ + E +K+D + P A + + + T +FT L+D + + A C +S S ++W ++L + R+ +E + ++ ILN A D+G + C A ++S RL+ G+ P +P + ++ E+ ++W YL I YR++ R + W T+ +D+ ++++L Y R+ AQN +G S+++ + Q + I LK + N M + +N + D+ ++ +DD R +VIR+ + ++ + AV ++ EY R + E++ L +F L E + +R F ++ Y+E V +RQ+ + FLH + H ++ P I+ ++ +S+ +KL+ Q V G VK + T + +PE+ E+ +SD+W +G+++F LLA P + + ++ V N + L+PV S+ F +LKKSP R D L+H + DP + E S++ L Sbjct: 6857 APSATAIERIKADIEKVTPCATKKN-DDGTFAPIFTARLRDVYLRKNQPA-----IFECAVS--ASPAPKVTWDFQGKILESNDRVTIE--QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPEGPTYLEGI---TYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIVQTHGKGAPKLQIDVLKSEIRLNVVSM-PQKSTNQLGGISEESEEDSEARTANEDMKSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAISEYESLRDGQHENVQ---RLIAAFNNSNFLYLLSERLYEDVFSRFVFNDY---------------YTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMF--QSKRSWVVKLVDFGRAQKVSGAVKPVDFDTK-----WASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDREEEIKENVINVKCDPNLIPV--------------NASQECLSFATWALKKSPVRRMRTDEALSHKFLSSDPSMVRRRESIKYSASRL 7415 HSP 4 Score: 83.1889 bits (204), Expect = 5.606e-15 Identity = 185/831 (22.26%), Postives = 333/831 (40.07%), Query Frame = 2 Query: 4013 QWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICF-NPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNN--NLSFLLIDSVKLEDSGTY--ICQGFTNKELISECKITLNVV---DNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEIL---EMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFN-STKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLR--NDMPFGDPCVL---DNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGEL-----LSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVD-----ILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETL--DSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPL 6409 +W+ N + + N K + + + LEI + QL D+ YK+ N + + L IA I K L+ + E G+ L V+ K+IKW K K + Q ++ N L+I +D+ Y + S C +T+ + I L+ QV + I + + IE + + +V W+ NG+ L K+ + I +N + E+ ++ G Y+ + N+ G S+ + ++ VE +I L + K+ ITEG V + + + +W K+ + N F K + L A D+ YK +LE + + ++ K++ + +++ ++ V++ + V +WLR N + G ++ D+ L I S + + +G Y V NE K S GE+ + +E + E + VE P + + W K+++ + + P Y L + ++ D Y + ++ ++ D L V+P ++ I L+D+ + EP+ V+ + +VE G K I W+ +E+ DA+ +F + F+LTIP++ + G Y + + ND G V S G + + ++ SE + ++PL KD E+ + + L C + +P P+++W KDG L D + R LD TL I A+ D G+Y N G T++ + VT E E S V PL Sbjct: 3791 KWYKNGKEIPNAKAKDNGDGSYS-LEIPNAQLDDTADYKVVVSNDAGDADSSAALTVKLPGIA-IVKGLE----DAEVPKGKKAVLQVETNK-KPKEIKW------YKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQV--------VSIGSPIKLE--IETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDT--GDYKVEVANEAG-SANSSGKITVEP-KITFLKPL-KDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKI-------VLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPEDV-RWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKD-AGEYTVEVINESG--------------KAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK---WYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLK--------------IVDGLKDVDVE-EPQPVELKVKVE--GIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYS-GSVVHVKSAKSSEPTSGANFLSPL-----KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVA--LDG--TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVT--EQGEQPSKPKFVIPL 4537 HSP 5 Score: 74.7146 bits (182), Expect = 2.097e-12 Identity = 168/795 (21.13%), Postives = 299/795 (37.61%), Query Frame = 2 Query: 4082 QLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAP-IKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTY-ICQGFTNKELISECKIT------LNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSD--ILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTA-----RTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMP--FGDPCVLDNPFIDLYIESPQ--VNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELS----VESRVPTKSIDSAVWLKDEK---------LLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY-SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNF--TLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 +L I L D+G+Y + + S K V P I + L+ NIE G+ V+V ++ +KW + ++K + L+ K+I K L I+ +L+D Y + + S +T L +VD + D +E Q V ++ +E + W+ NG+ L+ +D + +G+ + L I + +S G Y ++ N G + ++ + E S K+ E+ EG+ L L+ E + W KD + ++ I L A+ +D G Y+ + G TV Q + + + + + D K +V+V + +QW N +P F D LD+ Y + + E G KCI NE E V +F+ + L + D +I + +E V W KD K + N D I + PF + +D G+Y + +NE I + +E + P+I PL+D + N + ++ +V+ +W+ + + A++ IQ+ D L I + E+ G Y N G + + S + ++ +Q ++ P FTK L D+ ++ L C + DP P+I W ++G+ L N +++ P+ +L + E+ + D G Y C N G T+A V Sbjct: 4196 RLIIPSADLKDAGEYTVEV--INESGKAKSDAKGEVDEKPEIVRGLE----NIEIPEGDDDVFKVEVSAPVRQ-VKWYKNDQEIKPNSHLEAKKIGPKKYE----LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDV------------DVEEPQPVELKVKVEGIPK--VIKWYKNGQELKPDADGFKFEEKPESGEFS-LTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQP----SKPKFVIPLKTGAALPGDKKEF--NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDETV---CEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPF---------EESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTV-NGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINT----SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL----RNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHV 4937 HSP 6 Score: 74.7146 bits (182), Expect = 2.397e-12 Identity = 62/273 (22.71%), Postives = 127/273 (46.52%), Query Frame = 2 Query: 9584 KKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQ--IEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPEL-LKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSAC-------VFIRKCLLLKTG-------ERLTSSDSLSHEWF 10351 K ++Q+ D R+ KG +S + ++ +T+ K ++ I SE++ +++ H N+ + A + +L L+ E+L + ++ ++ E QV + + Q+ A+ +LH + HLD+ P NI+ K + ++KL F A ++ G+ + + + +++PE + P+ SDMW +G++TF L G E D+ E+ + + N C ++CL T R+ + ++LSH++ Sbjct: 7131 KSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAI--SEYESLRDGQHENVQRLIAAFNNSN-FLYLLSERLYEDVFSRFVFN-DYYTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMFQSKRSWVVKLVDFGRA--QKVSGAVKPVDFDTKWASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDR--EEEIKENVINVKCDPNLIPVNASQECLSFATWALKKSPVRRMRTDEALSHKFL 7395 HSP 7 Score: 72.0182 bits (175), Expect = 1.278e-11 Identity = 200/875 (22.86%), Postives = 340/875 (38.86%), Query Frame = 2 Query: 3932 LNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCK---KDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSI---API-KKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNK----ELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIEC---TSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSST---------ARTELNV--ENIQI----------DCLNSVT-------------KNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNG-IFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISV---EVLNWK-----QGVIQWLRN--DMPFGDPCV---LDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSP-ILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTI-IMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSE-ISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVT 6358 L + E E + L+ +I + + +WF +D+ + N KD S L I + D G Y C EA + K T V AP+ + LKP E G+ L V VEG + ++KW +D + I + I +K N L+I D G Y CQ TNK E + E KI + + + E K + + D ++EC +H + +F N + +E+ + ++ +G I +L IQN + G Y C N G ++T A+ E +V E+ Q+ D +S T ++ +TE + L+ + E + +W+K+ + + + K+ LT D+G Y+ E E + + I+ T E K+ E + L KP +++V VL K + ++W +N ++ D LD+ L + + ++++ Y+C +NE + + ++T+ K+ V+P EL + V+E T K E V P W KD L E D R+ L++ D K D G Y +++ S D V P+ E K IKK L D+ N + K VE G K + W+ E + + I ++ + L I +A G Y + ++ D V S +++ +E IS P F K L D + + L + PK + W K+G+ + + +V+ L + L I + + +D G Y N G ++A + V+ Sbjct: 2851 LEVREQETLDLKVTVIGTPVPNV----EWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVY-TCKATNEAGEA-KTTANMAVQEEIEAPLFVQGLKPY----EVEQGKPAELVVRVEGKPEPEVKW--FKDGVPI-AIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQA-TNKAGKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDT---VVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI-KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEA-------ENEYGSAWTE--GPIIVTLEGAPKIDGEAPD-FLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMD-EYRCEASNEFGDV-WSDVTLTVKEPAQVAPGFFKELSAIQVKETETA---KFECKVSGTKP-----DVKWFKDGTPLKE-DKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEV---SNDAGVANSKVPLTVVPSETLK------IKKGLTDV---NVTQGTKILLSVEVEGKPKTVKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKIS---------LPSFKKGLADQSVPKGTPLVLEVEIEGKPK-DVKWYKNGDEIK----DGKVEDLGNG-KYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVS 3659 HSP 8 Score: 70.8626 bits (172), Expect = 2.901e-11 Identity = 116/503 (23.06%), Postives = 200/503 (39.76%), Query Frame = 2 Query: 4919 WSKDDIDCSNN--GIFNSTKNKNCFNLTKLKAEITDSGVY------KFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDP----CVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFK-DEKVVSPILGELLSCTVEEVNTIEDEKIEL-SVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY----SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFE--NEEI--DAENMEFIQWSCDNYFALTIP-AAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 W KDD+ + F S ++ F +T ++TD+G Y ++ ++ + P + + C++ ++I EV W + + WL +D P D L I Q ++ +G+Y + NE E E+ V+ D+ V+P T+E V E E++ SV + P I +W + K L+E++ I C L ++DV GM S ++ +S D +KVR P P KPL+D ++ + V FEV+ SG + F +E+ E +E + D ++ ++IP + +KH G+ + N+ G S RL++ EQ E AP F K ++D + + E + +P P++ W +G +D VKI + L I A+ +G C N +G T+A ++V Sbjct: 581 WYKDDVQLHEDERHTFYSDED-GFFAMTIDPVQVTDTGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKE----CKEGDVI-------DFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPDD-TGVYTVKIQNEFGSIESKAELFVQADPDKNHVAP----EFQATIEYVECDEGEEVRFKSVITGDPNPEI---IWFINGKPLSESEKVKFISEDGICI-LTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP------------PTFNKPLEDKTVQEKSTVV---FEVDVSGWPEPTLTFTLCGKELKNGEEGVEIV--GHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV-------EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPG--VKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVV 1034 HSP 9 Score: 70.4774 bits (171), Expect = 3.954e-11 Identity = 83/318 (26.10%), Postives = 138/318 (43.40%), Query Frame = 2 Query: 5792 EPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDG--------RLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFT--LIITEAEVEDSGRYCCLGTNFLGYDTT--EAVIIVTDSEPKESDSS-RIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPI 6706 E + +K E +V+ S + +W+ + + + I S D L IP+ G Y + N G + G R S RS +++ + AP + L++I I K++ RL C+ DPKP I W KDGE + R++++ E P+ L++ A +D+G Y C+ N G T + +I D +P++ DSS R P LT +K D + ++ + + I ++ L S + K M+ + T L S + RCVA +E+G T S E+ I + I Sbjct: 5074 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRS--ADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERV---FPYGRLQLI-ESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSV-TFECLPFGNPFPSIKWLKDGLELFS-DEKIKMEAAADGTQRLILSDVTFLSEGYFRCVATNEHG--TASTKAELVIEGDRTI 5381 HSP 10 Score: 69.707 bits (169), Expect = 7.102e-11 Identity = 221/1065 (20.75%), Postives = 425/1065 (39.91%), Query Frame = 2 Query: 3260 FFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKP--IDSNIETC--PGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLL-IDSVKLEDSGTY-ICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNG-EILEMKSDILSDIKNNGKIA-ELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGM-VDGKLLEL-VHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVL------DNPFIDLYIESPQVNEHSGLYKCIVTNEK-SETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFC---YNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF---IRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLG-YDTTEAVIIV 6355 FF L I+ E + K D WF + L K + + + S + G ++ + + + ++ + V+ E + G D + + G + L++ + P K W+ +E + + + + E++ K+ I + E S YR+V + +S E + ++ K KI F+ L ++ + ++LE +I G K W+ N + +K+ + D + +L I Q D G+Y + A++ G++ S A + + KP + + T GE+ T V V+G K +KW K K + + + K N + S+ L I + ++ED+ Y + + S +T+ + D+ D ++ ++ +++ + T ++ V W+ NG EI K+ K+NG + L+I N Y+ ++ N G++ ++ L V+ I + + ++ E+ +G + L+V + +K + +W K+ + + ++ + N L A D+ YK DG + TV+ L E ++ ED ++S P+ + +E + ++W +N ++P + DN ++ L I S V E +G YK V NE S +ITV+ K + P+ + ++ E E E SVE+ + + W K+ + E P I++ Y L++++ DA Y + + ESS + VK + K I K L+ + K + +F I+ EPE V+ W + I A I+ D + L IP+A K G+YT++V N+ G +SD + E+ E+ P + L++IEI ++ + P ++ W K+ + + KI + + L I A+++D Y + +N G D++ A+ +V Sbjct: 3380 FFKELSAIQVKETETAKFECKVSGTKPDV----KWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQ-----GTKILLSVEVEGKP----KTVKWYKGTETVTSSQTTKIVQVTESEYKLEIESA--EMSDTGAYRVVLSTDSFSVESSATV--TVTKAAEKISLPSFKKGL------ADQSVPKGTPLVLEVEI-EGKPKDVK----WYKNGDEIKDGKVE-DLGNGKYRLTIPDFQEKDVGEYSVT----AANEAGEIE-----SKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKW------YKNGKEIPDAKT--KDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQ--VKWYKNGKEIPNAKA------KDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSS-AALTVKLPGIAIVKGL-EDAEVPKGKKAVLQVETN-KKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVK-------LPAKEPKIIKGLEDQ--VVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV-LEIPS-SVVEDTGDYKVEVANEAGSANSSGKITVEPKI-TFLKPLKDQSIT---------EGENAEFSVETNTKPRIVK---WYKNGQ---EIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGAKMVFEVKIQGEPEDVR--------------WLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDA------KGEVDEK--------PEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPK--KYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4323 HSP 11 Score: 68.5514 bits (166), Expect = 1.547e-10 Identity = 157/732 (21.45%), Postives = 287/732 (39.21%), Query Frame = 2 Query: 4394 LLIDSVKLEDSGTYICQGF-------TNKELISE--CKITLNVVD------------NISDTLQCQVKFEKDKYS-IEINQDVTM----RALIEC---TSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNS-------STARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTV----QVNP-----IQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVL-----DNPFIDLYIESPQVNEHSGLYKCIVTNEKS-ETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDG-ETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKP 6406 L I + K ED G Y C+ TN +L + K+ +V D + DT + + +E+ + T+ +A+++C + W G+ +EM + + ++ K++G + L N ++ G Y C EN+ G++ T ++ D L V + +T G LE + +W K+ + ++ + + LT A++ D Y+ E + G + V TV QV P + +I + K C+ +S +KP ++W ++ P + + D+ L IE + ++ G Y+ V+N+ V +TV V S L + + +VN + KI LSVE K++ W K + + + + + Y L + +M+D G Y + ++ ESS + V TK K + +P KK L D + P+ EVE G K + W+ +EI +E + + + LTIP EK G+Y++ AN+ G + S ++++ + EI ++ + + E N ++ P + W K+G E D+K + + +++L I A+VED+ Y + +N G + A + V K +D + VKP Sbjct: 3104 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLT-LTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAV-VTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECK-----VSGTKP-------------DVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQ-GNYRIEVSNDAGVANSKVPLTV------VPSETLK--IKKGLTDVNVTQGTKILLSVEVEGKPKTVK---WYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTV----------TKAAEK-ISLPSFKKGLADQSV---PKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGKVEDL---GNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTT--------------VKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD------NGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTV-----KLADDGKDKVKP 3760 HSP 12 Score: 66.2402 bits (160), Expect = 7.973e-10 Identity = 85/362 (23.48%), Postives = 148/362 (40.88%), Query Frame = 2 Query: 5333 YKCIVTNE-KSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP--FCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFI-QWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDE---FPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVI-IVTDSEPKE 6376 YK I TN + T +IT K V +P+ + L T V E+ K+E+ V P W KD+K ++E D + P + L+++ TDAG Y+ K + ESS + E+ ++L+ P + L ++ ET V+ W + + + ++ I + +++TI A + GKY + N G +++ +++ + P F +KL +E+ KE+ L+ +++ P+P + W KD D+ V ++ + +F+L I +A D G Y C N G T A I+ DS P E Sbjct: 2525 YKAIATNSIGTATSTSKITTK-----VEAPVFEQGLKKT--SVKEKEEIKMEVKVGGSAP-----DVEWFKDDKPVSE-DGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEA--------------EVTQSLEKPTFVRELVTTEVKIN-ETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVV-----------KNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKD----DTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPE 2843 HSP 13 Score: 65.0846 bits (157), Expect = 1.903e-9 Identity = 174/820 (21.22%), Postives = 297/820 (36.22%), Query Frame = 2 Query: 4085 LEIAHCQLSDSGQYKI-CFNPLEASKCGKVTGLFLVSIAPIKKNLKPID-----SNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSF-LLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHY-SVSWFFNGEILEM-KSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS--NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGM-VDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMP--FGDPC---VLDNPFIDLYIESPQVNEHSGLYKCIVTN-------------------------------EKSETEFVEITVKFK-DEKVVSPILGELL-SCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKI--------NESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILD-EFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSE 6367 + I +L DSG+Y NP +K F V KNL P + S +E ES TL V V G + ++W + + D + + QK SF L I+ + D G Y C+ + E T N I D++ + F + +E+ + T+ + T +V WF + + + + S I + + +G L I+ G+Y C N+ G + T E I+ K E+ +G L V E + + + +W KD + + N + L D G Y + GK + + + T +E + I E + +++ +V I++ +ND P G VL++ I L I++ + E G Y+C N E + E V T K D +P ELL SCTV E K + ++ +V + W K+ K + + L +V DAG Y + E + + ++ PK + + P +P++ + ET E ++ W+ EE+ + I+ D LT+ A +Y + +N+ G V SD L++ E +AP F K+L I++ E + C+ + KP + W KDG L ++RV + L+I +++ +D G Y +N G ++ + V SE Sbjct: 2705 ITIKDARLEDSGKYACRATNPAGEAK---TEANFAVV-----KNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNV----HVIQKQTAVGSFSLTINDARQGDVGIYSCRA---RNEAGEALTTANF-GIIRDSIPPE--FTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHT-LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEK-QTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNAK-KEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTE-------KQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPK----------IDGEAPDFLQPVKPAVV-TVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVK----------EPAQVAPGFFKELSAIQVKETETAKFECK-VSGTKPDVKWFKDGTPLKE---DKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSE 3471 HSP 14 Score: 60.4622 bits (145), Expect = 4.069e-8 Identity = 94/384 (24.48%), Postives = 157/384 (40.89%), Query Frame = 2 Query: 5282 FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSP--ILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNET-DPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEI-DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVK 6403 F + I+ QV + +G Y C+ TNE + K EK +P + +L +E + I+ E VE P + VWL D++ L + D RL Q L +RD + D G+Y++KI ES ++ V+ P KN P+ + ++ + +E E V+F+ + + IWF + + ++E ++FI S D LTI G T Q +N +G DGRL + + P F K L+D + K + + P+P + +T G+ L + + D F ++ T + D G N G + A + V + E +ES S+ +K Sbjct: 603 FFAMTIDPVQVTD-TGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVID---FECEVEG-WPEPEL---VWLVDDQPLRPSHDFRLQYDGQ--TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPD----------KNHVAPEFQATIEYVEC-DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFI--SEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPP-----------APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIVAKAQNEHGTAESRARLTV-EQEEEESRSAPTFLK 950 HSP 15 Score: 58.151 bits (139), Expect = 1.850e-7 Identity = 40/179 (22.35%), Postives = 79/179 (44.13%), Query Frame = 2 Query: 9050 LSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIY-FIIKNLEEDDFGEYCA-----LDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRV 9568 + +K E+K + + W F + K D +++ G++ ++K D G+Y A + ++ + + PT + L + ++E ++SV + P P V W ++ + + + VI + + G+YS+ I L D G+Y+ RA N G A+ + N V Sbjct: 2560 VKEKEEIKMEVKVGGSAPDVEW-FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAV 2737 HSP 16 Score: 56.9954 bits (136), Expect = 5.354e-7 Identity = 41/138 (29.71%), Postives = 66/138 (47.83%), Query Frame = 2 Query: 5957 CGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP 6370 GKYT V N G + L+++ E E+ E AP F L+D + E + L C+++ +PKPK+ W D +T+ + + V+ ++ T IT +E+ G+Y C+ N G TEA + V P Sbjct: 2319 AGKYTCIVENTAGKDTCEATLTVI---ESLEKKSEKK--APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESIT--VESVEGVERVT--ITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAP 2447 HSP 17 Score: 56.225 bits (134), Expect = 7.868e-7 Identity = 84/362 (23.20%), Postives = 144/362 (39.78%), Query Frame = 2 Query: 5327 GLYKCIVTNEKSETEF-----VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVE-SRVPTKSIDSAVWLKDEKLLNETDPRLTI-IMQPFCYNLILRDVKMTDAGMYSL-------KINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPN--FTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDS 6364 G+Y C+ NE + E VEI ++EK ++ +E+ + I LS + +P S+ VW KD L D R +I + L + D D G Y IN +S + VKV + ++K+ +E F K L D++ + ++ + V + W+ + + I+ S D +LT+ + G Y + N G ++ + + +E+ P F +L D+ + I L C++ P P + W+KDG L + R + +E + L I A V D G Y C+ TN G TT++ + + D Sbjct: 4706 GVYMCVAVNELGQAETQATYQVEILEHVEEEKRRE--YAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASV---VWYKDGLPLR-ADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTIN-TSCSVNVKVPKQEVKKEGEEPF-------FTKGLVDLWA-DRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL---IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDG 5049 HSP 18 Score: 55.8398 bits (133), Expect = 1.046e-6 Identity = 208/1044 (19.92%), Postives = 402/1044 (38.51%), Query Frame = 2 Query: 3362 WFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNV-LAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKP--IDSNIETC--PGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLL-IDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFE-----KDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIE---ITEGNELNLEV-VSEIEKDLQFQWSKDDIDCSNNGIFNSTK-NKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFI---------DLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPL 6409 W+ E + + V V+ES+ ++ + E+S +R+ FS E S V + K +S + + + G L L + + P K+ W+ N + I K E + K ++ IP+ ++ G +Y + E E K+ + P+I S L V + + E K+ G + K W+ N + + + K + + + LEI + Q+ D+ YK+ + +A L + K +KP + I T GE+ T V V+G K+ +KW K K + + K N + S+ L I + +L+D+ Y K ++S N + + VK K E+ + +E + W+ NG+ + SD + +L I + + Y+ ++ ++DGN++ + L V+ + + K +E ++ G+ + LE+ S K +++ + ++ + K + N + L + + D+G YK +E+ + N I T E ++ + + +++ + SVE N K +++W +N G ++ FI L I++ V + + YK ++ N E E ++TVK + + G + + + KI+ E WL+D +++ + + Y LI+ + DAG Y+++ INES K E+ + P+I + L++I I PE F+VE S + + W+ ++EI + + + L I A Y + ++N G S L+++ + + LKD+++ + + L ++ PK I W K+G+ L + + E F+L I ++ D G Y + N G + +V+ V ++ E S + PL Sbjct: 3505 WYKGTETVTSSQTTKIVQVTESEYKLEI--ESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP----KDVKWYKNGDEIKDGKV---EDLGNGKYRLTIPDFQEKDVG--EYSVTAANEAGEIESKAKVN---VSAKPEIV-----SGL------VPTTVKQGETATFNVKV-KGPVKGVK----WYKNGKEIPDAKTKDNGDGSYS-LEIPNAQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQ-VKW------YKNGKEIPNAKA--KDNGDGSYSLEIPNAQLDDTADY-------KVVVS------NDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEI-TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEP--KIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYK---------VEVANEAGSANSSGKI--TVEPKITFLKPLKDQSITEGENAEFSVET-NTKPRIVKWYKN----GQEIKPNSRFIIEQKTDTKYQLVIKN-AVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPED---------VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESG---------KAKSDAKGEVDEK---PEIVRGLENIEI---PEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLK------------IVDGLKDVDVEEPQPVELKVKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPL 4437 HSP 19 Score: 53.9138 bits (128), Expect = 4.300e-6 Identity = 128/612 (20.92%), Postives = 242/612 (39.54%), Query Frame = 2 Query: 4625 WFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNS-STARTELNVEN---IQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGM----VDGKLLEL-VHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGV-IQWLRNDMPFGDP---CVLDNPFIDLYIESPQVN-EHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVW-LKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRM-MCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPL 6409 W+ NG +LE + ++ IKN + L I N +S + E N+ G+S S+A+ +N + I +D SVT I+ TE E + ++ W+ ++ + + K ++ + L A+I +G K D K +L V V+ +S LT + + + +PL ++E+ G + WL N P V+D+ ++ + E SG N E E ++TV ++K E + T+E E ++ S + V K + + W L ++KL+ + ++ + + ++ ++ M G ++ S + + K + K ++P+ + D ++ E E VKF VE W E + +++ D + I A + G+ + + N +G + D +L++ + AP F K L+D I E ++ ++ + PKPKI W KDG + S + V+ +E + L I + ++ED GR + G A + V P + + + P+ Sbjct: 1373 WYQNGNLLEDGKNGVT-IKNEENKSSLIIPNAQDSGKITVEA--SNEVGSSESSAQLTVNPPSTTPIVVDGPKSVT--IKETETAEFKATISGFPAPTVK--WTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLT-------------DKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNKKP------EFVQAPQNHETTLE-ESVKFS--AIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLK--------VDKKTEVPKFTTNMDDRQVK-EGEDVKFTANVEGYPEPSVAWTLNGEPV-SKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAV-----------KKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVE--EEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQSDIAPI 1932
BLAST of Serine/threonine kinase vs. Ensembl Celegans
Match: unc-89 (Muscle M-line assembly protein unc-89 [Source:UniProtKB/Swiss-Prot;Acc:O01761]) HSP 1 Score: 136.732 bits (343), Expect = 3.618e-31 Identity = 157/617 (25.45%), Postives = 269/617 (43.60%), Query Frame = 2 Query: 8714 ITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGI-------------GKPSMVIKKIRRSDN---LNSPTTEKA--MMLQEKHCLAVPMFC--------CLSQKAELKFTKLMEYKLDKITWTFNNAKVDVND--ERYKIFSAETYGIYFIIKNLEEDDFGEY-C-ALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTY--SLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPE-------KKSVQINIGDVNDRYYTMKK----LAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIY-----EKLQGLS-LAEYITQLSHWC----ESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHM--GL------TSP-FSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ--LYNEDS----NDAISN---SACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +TLSW P + +P Y T +E R + E+ WS+ + NI + + +L+ +YQ R+ +GI P V RR++ L P EKA M E++ A P F C + + I W F +D + + K+++ I +++ G+Y C A ++ D Q+ ++ + P + L N + + + + V++D +P PE+ W + W+ I S R +D G Y SL+I+ + D G YS A N G A + V+A + ++ V I V + Y +K A+G+ R V EK+T EF+ + I++ + + ++ H IV++ + D+ L L+ + GLS LA +++ E+ VR+ + QL+ A+ ++H+ R+ HLD++PE I++ ++ LKL DFG R + GL SP F +PE+++ P+ +DMWS G+LT++ L G + + D L N DS + + N A F++K L RLT ++L H W Sbjct: 5179 LTLSWIPTKRAPPRYPQVTYVIEIREL-----PEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAENIYGISDPSPASPPSRLMAPPQPVFD--RRTNKVIPLLDPYAEKALDMRYSEQYACA-PWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVGQYQCFAKNDYGDAQQNIMVDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQD---GPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTVTVEAEGDYNDVELPRRRVTIESRRVRELYEISEKDEKLAAEGAPFR---VKEKATGREFLAQLRPIDDALMRHVDIH--NSLDHPGIVQMHRVLR--DEKLALVVFDNANSTIDGLSSLAHPGVEIAEPKGVNRETCVRVFVRQLLLALKHMHDLRIAHLDLRPETILL---QDDKLKLA---------DFGQARRLLRGLITGEIKGSPEFVSPEIVRSYPLTLATDMWSTGVLTYVLLTGLSPFHGDNDNETLANVDSCQFDSSPLGNFSYDAGDFVKKLLTEIPVSRLTVDEALDHPWI 5765 HSP 2 Score: 98.5969 bits (244), Expect = 1.266e-19 Identity = 170/765 (22.22%), Postives = 302/765 (39.48%), Query Frame = 2 Query: 4283 GFSKKDIKWKVLEDDLKQDKILQE---KRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEM-KSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDD--IDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFI----------DLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDE-KLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INESSVDILV---KVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSC--DNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCI-----------------------APLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKI-LDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVT-DSEPKESDSSRIIVKPLCAPVLT 6427 G S D++W K DK + E + + + L++ D+G Y + +N +E V ++ + E ++IN+ T+ ++ SV W +G+ ++ S +++ ++ +G + + I++ G Y C N G + T V+N+ +E+ E L V + +W KDD I N + F+LT A D G+Y + G+ L +F + + I T L++ + E + D K +I V N ++W ++D P +DN I L I+ + E G+Y C TNE E + + V+ E++ +P+ + L E + + EL V RV K W KD + + + + + L+++D D G Y+ + N++ D V K+ KQT E K L I +PL++ F E +TV E +V + + I FF+N++ E + +Q D LTI A ++ G Y + N G ++ L + +++ E + + AP F + L+ + K+ L C++ +P+PKI WTK+G+ ++ ++ RV+ + TL D+G Y C N G TE IIVT + PK + ++P+ V+T Sbjct: 2100 GGSAPDVEW------FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKA-SNPAGTAESSAEAEVTQSLEKPTFVR---ELVTTEVKINETATLSVTVKGVPDP-SVEWLKDGQPVQTDSSHVIAKVEGSGSYS-ITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEV--REQETL--DLKVTVIGTPVPN-----VEWFKDDKPIN----IDNSHIFAKDEGSGHHTLTIKQAR-GEDVGVYTCKATNEAGEAKTTANMAVQ---EEIEAPLFVQGLKPYEVE----QGKPAELVV--RVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKPLFI----EPLKETFAV-EGDTVVLECKVNKE-SHPQIKFFKNDQ-PVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVE---MSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVT 2819 HSP 3 Score: 93.9745 bits (232), Expect = 3.569e-18 Identity = 131/612 (21.41%), Postives = 246/612 (40.20%), Query Frame = 2 Query: 10619 TPNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILN-ATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSP-----YLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRN-----IHSLKQALIFNRKWMLTSRQSNHFNDL--------------HDLIKDIS--SDDI-------------RMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFV-GTVKEQESLTTHKPSIFKAPEYRY-ESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNT--NTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPL 12319 P+ + E +K+D + P A + + + T +FT L+D + + A C +S S ++W ++L + R+ +E + ++ ILN A D+G + C A ++S RL+ G+ P +P + ++ E+ ++W YL I YR++ R + W T+ +D+ ++++L Y R+ AQN +G S+++ + Q + I LK + N M + +N + D+ ++ +DD R +VIR+ + ++ + AV ++ EY R + E++ L +F L E + +R F ++ Y+E V +RQ+ + FLH + H ++ P I+ ++ +S+ +KL+ Q V G VK + T + +PE+ E+ +SD+W +G+++F LLA P + + ++ V N + L+PV S+ F +LKKSP R D L+H + DP + E S++ L Sbjct: 6384 APSATAIERIKADIEKVTPCATKKN-DDGTFAPIFTARLRDVYLRKNQPA-----IFECAVS--ASPAPKVTWDFQGKILESNDRVTIE--QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPEGPTYLEGI---TYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIVQTHGKGAPKLQIDVLKSEIRLNVVSM-PQKSTNQLGGISEESEEDSEARTANEDMKSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAISEYESLRDGQHENVQ---RLIAAFNNSNFLYLLSERLYEDVFSRFVFNDY---------------YTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMF--QSKRSWVVKLVDFGRAQKVSGAVKPVDFDTK-----WASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDREEEIKENVINVKCDPNLIPV--------------NASQECLSFATWALKKSPVRRMRTDEALSHKFLSSDPSMVRRRESIKYSASRL 6942 HSP 4 Score: 82.8037 bits (203), Expect = 7.062e-15 Identity = 186/832 (22.36%), Postives = 336/832 (40.38%), Query Frame = 2 Query: 4013 QWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICF--NPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNN--NLSFLLIDSVKLEDSGTY--ICQGFTNKELISECKITLNVV---DNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEIL---EMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFN-STKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLR--NDMPFGDPCVL---DNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGEL-----LSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVD-----ILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETL--DSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPL 6409 +W+ N + + N K + + + LEI + QL D+ YK+ + +A +T + L IA I K L+ + E G+ L V+ K+IKW K K + Q ++ N L+I +D+ Y + S C +T+ + I L+ QV + I + + IE + + +V W+ NG+ L K+ + I +N + E+ ++ G Y+ + N+ G S+ + ++ VE +I L + K+ ITEG V + + + +W K+ + N F K + L A D+ YK +LE + + ++ K++ + +++ ++ V++ + V +WLR N + G ++ D+ L I S + + +G Y V NE K S GE+ + +E + E + VE P + + W K+++ + + P Y L + ++ D Y + ++ ++ D L V+P ++ I L+D+ + EP+ V+ + +VE G K I W+ +E+ DA+ +F + F+LTIP++ + G Y + + ND G V S G + + ++ SE + ++PL KD E+ + + L C + +P P+++W KDG L D + R LD TL I A+ D G+Y N G T++ + VT E E S V PL Sbjct: 3318 KWYKNGKEIPNAKAKDNGDGSYS-LEIPNAQLDDTADYKVVVSNDAGDADSSAALT-VKLPGIA-IVKGLE----DAEVPKGKKAVLQVETNK-KPKEIKW------YKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQV--------VSIGSPIKLE--IETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDT--GDYKVEVANEAG-SANSSGKITVEP-KITFLKPL-KDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKI-------VLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPEDV-RWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKD-AGEYTVEVINESG--------------KAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK---WYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLK--------------IVDGLKDVDVE-EPQPVELKVKVE--GIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYS-GSVVHVKSAKSSEPTSGANFLSPL-----KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVA--LDG--TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVT--EQGEQPSKPKFVIPL 4064 HSP 5 Score: 74.7146 bits (182), Expect = 2.390e-12 Identity = 156/744 (20.97%), Postives = 280/744 (37.63%), Query Frame = 2 Query: 4232 NIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTY-ICQGFTNKELISECKIT------LNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSD--ILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTA-----RTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMP--FGDPCVLDNPFIDLYIESPQ--VNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELS----VESRVPTKSIDSAVWLKDEK---------LLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY-SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNF--TLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 NIE G+ V+V ++ +KW + ++K + L+ K+I K L I+ +L+D Y + + S +T L +VD + D +E Q V ++ +E + W+ NG+ L+ +D + +G+ + L I + +S G Y ++ N G + ++ + E S K+ E+ EG+ L L+ E + W KD + ++ I L A+ +D G Y+ + G TV Q + + + + + D K +V+V + +QW N +P F D LD+ Y + + E G KCI NE E V +F+ + L + D +I + +E V W KD K + N D I + PF + +D G+Y + +NE I + +E + P+I PL+D + N + ++ +V+ +W+ + + A++ IQ+ D L I + E+ G Y N G + + S + ++ +Q ++ P FTK L D+ ++ L C + DP P+I W ++G+ L N +++ P+ +L + E+ + D G Y C N G T+A V Sbjct: 3768 NIEIPEGDDDVFKVEVSAPVRQ-VKWYKNDQEIKPNSHLEAKKIGPKKYE----LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDV------------DVEEPQPVELKVKVEGIPK--VIKWYKNGQELKPDADGFKFEEKPESGEFS-LTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQP----SKPKFVIPLKTGAALPGDKKEF--NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDETV---CEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPF---------EESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTV-NGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINT----SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL----RNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHV 4464 HSP 6 Score: 74.3294 bits (181), Expect = 2.971e-12 Identity = 62/273 (22.71%), Postives = 127/273 (46.52%), Query Frame = 2 Query: 9584 KKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQ--IEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPEL-LKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSAC-------VFIRKCLLLKTG-------ERLTSSDSLSHEWF 10351 K ++Q+ D R+ KG +S + ++ +T+ K ++ I SE++ +++ H N+ + A + +L L+ E+L + ++ ++ E QV + + Q+ A+ +LH + HLD+ P NI+ K + ++KL F A ++ G+ + + + +++PE + P+ SDMW +G++TF L G E D+ E+ + + N C ++CL T R+ + ++LSH++ Sbjct: 6658 KSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAI--SEYESLRDGQHENVQRLIAAFNNSN-FLYLLSERLYEDVFSRFVFN-DYYTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMFQSKRSWVVKLVDFGRA--QKVSGAVKPVDFDTKWASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDR--EEEIKENVINVKCDPNLIPVNASQECLSFATWALKKSPVRRMRTDEALSHKFL 6922 HSP 7 Score: 72.4034 bits (176), Expect = 1.162e-11 Identity = 199/874 (22.77%), Postives = 339/874 (38.79%), Query Frame = 2 Query: 3932 LNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCK---KDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSI---API-KKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNK----ELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIEC---TSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSST---------ARTELNV--ENIQI----------DCLNSVT-------------KNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNG-IFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISV---EVLNWK-----QGVIQWLRN--DMPFGDPCV---LDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTI-IMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSE-ISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVT 6358 L + E E + L+ +I + + +WF +D+ + N KD S L I + D G Y C EA + K T V AP+ + LKP E G+ L V VEG + ++KW +D + I + I +K N L+I D G Y CQ TNK E + E KI + + + E K + + D ++EC +H + +F N + +E+ + ++ +G I +L IQN + G Y C N G ++T A+ E +V E+ Q+ D +S T ++ +TE + L+ + E + +W+K+ + + + K+ LT D+G Y+ E E + + I+ T E K+ E + L KP +++V VL K + ++W +N ++ D LD+ L + + ++++ Y+C +NE + + ++T+ K+ V+P + LS +V E K E V P W KD L E D R+ L++ D K D G Y +++ S D V P+ E K IKK L D+ N + K VE G K + W+ E + + I ++ + L I +A G Y + ++ D V S +++ +E IS P F K L D + + L + PK + W K+G+ + + +V+ L + L I + + +D G Y N G ++A + V+ Sbjct: 2378 LEVREQETLDLKVTVIGTPVPNV----EWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVY-TCKATNEAGEA-KTTANMAVQEEIEAPLFVQGLKPY----EVEQGKPAELVVRVEGKPEPEVKW--FKDGVPI-AIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQA-TNKAGKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDT---VVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI-KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEA-------ENEYGSAWTE--GPIIVTLEGAPKIDGEAPD-FLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMD-EYRCEASNEFGDV-WSDVTLTVKEPAQVAPGFFKELSAI--QVKETETAKFECKVSGTKP-----DVKWFKDGTPLKE-DKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEV---SNDAGVANSKVPLTVVPSETLK------IKKGLTDV---NVTQGTKILLSVEVEGKPKTVKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKIS---------LPSFKKGLADQSVPKGTPLVLEVEIEGKPK-DVKWYKNGDEIK----DGKVEDLGNG-KYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVS 3186 HSP 8 Score: 70.4774 bits (171), Expect = 3.750e-11 Identity = 101/402 (25.12%), Postives = 166/402 (41.29%), Query Frame = 2 Query: 5198 EVLNWKQGVIQWLRNDMPFGDP----CVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFK-DEKVVSPILGELLSCTVEEVNTIEDEKIEL-SVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY----SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFE--NEEI--DAENMEFIQWSCDNYFALTIP-AAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 EV W + + WL +D P D L I Q ++ +G+Y + NE E E+ V+ D+ V+P T+E V E E++ SV + P I +W + K L+E++ I C L ++DV GM S ++ +S D +KVR P P KPL+D ++ + V FEV+ SG + F +E+ E +E + D ++ ++IP + +KH G+ + N+ G S RL++ EQ E AP F K ++D + + E + +P P++ W +G +D VKI + L I A+ +G C N +G T+A ++V Sbjct: 197 EVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPDD-TGVYTVKIQNEFGSIESKAELFVQADPDKNHVAP----EFQATIEYVECDEGEEVRFKSVITGDPNPEI---IWFINGKPLSESEKVKFISEDGICI-LTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP------------PTFNKPLEDKTVQEKSTVV---FEVDVSGWPEPTLTFTLCGKELKNGEEGVEIV--GHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV-------EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPG--VKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVV 561 HSP 9 Score: 70.4774 bits (171), Expect = 4.433e-11 Identity = 83/318 (26.10%), Postives = 138/318 (43.40%), Query Frame = 2 Query: 5792 EPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDG--------RLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFT--LIITEAEVEDSGRYCCLGTNFLGYDTT--EAVIIVTDSEPKESDSS-RIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPI 6706 E + +K E +V+ S + +W+ + + + I S D L IP+ G Y + N G + G R S RS +++ + AP + L++I I K++ RL C+ DPKP I W KDGE + R++++ E P+ L++ A +D+G Y C+ N G T + +I D +P++ DSS R P LT +K D + ++ + + I ++ L S + K M+ + T L S + RCVA +E+G T S E+ I + I Sbjct: 4601 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRS--ADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERV---FPYGRLQLI-ESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSV-TFECLPFGNPFPSIKWLKDGLELFS-DEKIKMEAAADGTQRLILSDVTFLSEGYFRCVATNEHG--TASTKAELVIEGDRTI 4908 HSP 10 Score: 69.707 bits (169), Expect = 7.510e-11 Identity = 222/1065 (20.85%), Postives = 427/1065 (40.09%), Query Frame = 2 Query: 3260 FFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKP--IDSNIETC--PGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLL-IDSVKLEDSGTY-ICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNG-EILEMKSDILSDIKNNGKIA-ELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGM-VDGKLLEL-VHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVL------DNPFIDLYIESPQVNEHSGLYKCIVTNEK-SETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFC---YNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF---IRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLG-YDTTEAVIIV 6355 FF L I+ E + K D WF + L K + + + S + G ++ + + + ++ + V+ E + G D + + G + L++ + P T+K W+ +E + + + + E++ K+ I + E S YR+V + +S E + ++ K KI F+ L ++ + ++LE +I G K W+ N + +K+ + D + +L I Q D G+Y + A++ G++ S A + + KP + + T GE+ T V V+G K +KW K K + + + K N + S+ L I + ++ED+ Y + + S +T+ + D+ D ++ ++ +++ + T ++ V W+ NG EI K+ K+NG + L+I N Y+ ++ N G++ ++ L V+ I + + ++ E+ +G + L+V + +K + +W K+ + + ++ + N L A D+ YK DG + TV+ L E ++ ED ++S P+ + +E + ++W +N ++P + DN ++ L I S V E +G YK V NE S +ITV+ K + P+ + ++ E E E SVE+ + + W K+ + E P I++ Y L++++ DA Y + + ESS + VK + K I K L+ + K + +F I+ EPE V+ W + I A I+ D + L IP+A K G+YT++V N+ G +SD + E+ E+ P + L++IEI ++ + P ++ W K+ + + KI + + L I A+++D Y + +N G D++ A+ +V Sbjct: 2907 FFKELSAIQVKETETAKFECKVSGTKPDV----KWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQ-----GTKILLSVEVEGKP-KTVK---WYKGTETVTSSQTTKIVQVTESEYKLEIESA--EMSDTGAYRVVLSTDSFSVESSATV--TVTKAAEKISLPSFKKGL------ADQSVPKGTPLVLEVEI-EGKPKDVK----WYKNGDEIKDGKVE-DLGNGKYRLTIPDFQEKDVGEYSVT----AANEAGEIE-----SKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKW------YKNGKEIPDAKT--KDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQ--VKWYKNGKEIPNAKA------KDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSS-AALTVKLPGIAIVKGL-EDAEVPKGKKAVLQVETN-KKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVK-------LPAKEPKIIKGLEDQ--VVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV-LEIPS-SVVEDTGDYKVEVANEAGSANSSGKITVEPKI-TFLKPLKDQSIT---------EGENAEFSVETNTKPRIVK---WYKNGQ---EIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGAKMVFEVKIQGEPEDVR--------------WLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDA------KGEVDEK--------PEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPK--KYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 3850 HSP 11 Score: 68.1662 bits (165), Expect = 1.839e-10 Identity = 157/732 (21.45%), Postives = 287/732 (39.21%), Query Frame = 2 Query: 4394 LLIDSVKLEDSGTYICQGF-------TNKELISE--CKITLNVVD------------NISDTLQCQVKFEKDKYS-IEINQDVTM----RALIEC---TSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNS-------STARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTV----QVNP-----IQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVL-----DNPFIDLYIESPQVNEHSGLYKCIVTNEKS-ETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDG-ETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKP 6406 L I + K ED G Y C+ TN +L + K+ +V D + DT + + +E+ + T+ +A+++C + W G+ +EM + + ++ K++G + L N ++ G Y C EN+ G++ T ++ D L V + +T G LE + +W K+ + ++ + + LT A++ D Y+ E + G + V TV QV P + +I + K C+ +S +KP ++W ++ P + + D+ L IE + ++ G Y+ V+N+ V +TV V S L + + +VN + KI LSVE K++ W K + + + + + Y L + +M+D G Y + ++ ESS + V TK K + +P KK L D + P+ EVE G K + W+ +EI +E + + + LTIP EK G+Y++ AN+ G + S ++++ + EI ++ + + E N ++ P + W K+G E D+K + + +++L I A+VED+ Y + +N G + A + V K +D + VKP Sbjct: 2631 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLT-LTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAV-VTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECK-----VSGTKP-------------DVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQ-GNYRIEVSNDAGVANSKVPLTV------VPSETL--KIKKGLTDVNVTQGTKILLSVEVEGKPKTVK---WYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTV----------TKAAEK-ISLPSFKKGLADQSV---PKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGKVEDL---GNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTT--------------VKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD------NGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTV-----KLADDGKDKVKP 3287 HSP 12 Score: 66.2402 bits (160), Expect = 8.502e-10 Identity = 85/362 (23.48%), Postives = 148/362 (40.88%), Query Frame = 2 Query: 5333 YKCIVTNE-KSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP--FCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFI-QWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDE---FPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVI-IVTDSEPKE 6376 YK I TN + T +IT K V +P+ + L T V E+ K+E+ V P W KD+K ++E D + P + L+++ TDAG Y+ K + ESS + E+ ++L+ P + L ++ ET V+ W + + + ++ I + +++TI A + GKY + N G +++ +++ + P F +KL +E+ KE+ L+ +++ P+P + W KD D+ V ++ + +F+L I +A D G Y C N G T A I+ DS P E Sbjct: 2052 YKAIATNSIGTATSTSKITTK-----VEAPVFEQGLKKT--SVKEKEEIKMEVKVGGSAP-----DVEWFKDDKPVSE-DGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEA--------------EVTQSLEKPTFVRELVTTEVKIN-ETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVV-----------KNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKD----DTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPE 2370 HSP 13 Score: 64.6994 bits (156), Expect = 2.400e-9 Identity = 174/820 (21.22%), Postives = 297/820 (36.22%), Query Frame = 2 Query: 4085 LEIAHCQLSDSGQYKI-CFNPLEASKCGKVTGLFLVSIAPIKKNLKPID-----SNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSF-LLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHY-SVSWFFNGEILEM-KSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS--NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGM-VDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMP--FGDPC---VLDNPFIDLYIESPQVNEHSGLYKCIVTN-------------------------------EKSETEFVEITVKFK-DEKVVSPILGELL-SCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKI--------NESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILD-EFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSE 6367 + I +L DSG+Y NP +K F V KNL P + S +E ES TL V V G + ++W + + D + + QK SF L I+ + D G Y C+ + E T N I D++ + F + +E+ + T+ + T +V WF + + + + S I + + +G L I+ G+Y C N+ G + T E I+ K E+ +G L V E + + + +W KD + + N + L D G Y + GK + + + T +E + I E + +++ +V I++ +ND P G VL++ I L I++ + E G Y+C N E + E V T K D +P ELL SCTV E K + ++ +V + W K+ K + + L +V DAG Y + E + + ++ PK + + P +P++ + ET E ++ W+ EE+ + I+ D LT+ A +Y + +N+ G V SD L++ E +AP F K+L I++ E + C+ + KP + W KDG L ++RV + L+I +++ +D G Y +N G ++ + V SE Sbjct: 2232 ITIKDARLEDSGKYACRATNPAGEAK---TEANFAVV-----KNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNV----HVIQKQTAVGSFSLTINDARQGDVGIYSCRA---RNEAGEALTTANF-GIIRDSIPPE--FTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHT-LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEK-QTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNAK-KEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTE-------KQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPK----------IDGEAPDFLQPVKPAVV-TVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVK----------EPAQVAPGFFKELSAIQVKETETAKFECK-VSGTKPDVKWFKDGTPLKE---DKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSE 2998 HSP 14 Score: 62.003 bits (149), Expect = 1.604e-8 Identity = 61/272 (22.43%), Postives = 112/272 (41.18%), Query Frame = 2 Query: 5531 VWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYS-LKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKP------LQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLG 6325 W KD+ L+E + + + + + V++TD G Y+ + NE + T F+ LK+ + P L+D + E + + FE EVE + +W +++ + + +Q+ L I A G YT+++ N+ G + S L + + + +AP F ++ +E E +R + DP P+I+W +G+ L + +VK + E L I + G C G+N LG Sbjct: 107 TWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYG------------QASTSAFFRVLKVEKEAAPPAFVTKLRDKECK-EGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQTA-KLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH-------VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSE---SEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNRLG 354 HSP 15 Score: 60.4622 bits (145), Expect = 4.377e-8 Identity = 94/384 (24.48%), Postives = 157/384 (40.89%), Query Frame = 2 Query: 5282 FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSP--ILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNET-DPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEI-DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVK 6403 F + I+ QV + +G Y C+ TNE + K EK +P + +L +E + I+ E VE P + VWL D++ L + D RL Q L +RD + D G+Y++KI ES ++ V+ P KN P+ + ++ + +E E V+F+ + + IWF + + ++E ++FI S D LTI G T Q +N +G DGRL + + P F K L+D + K + + P+P + +T G+ L + + D F ++ T + D G N G + A + V + E +ES S+ +K Sbjct: 130 FFAMTIDPVQVTD-TGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVID---FECEVEG-WPEPEL---VWLVDDQPLRPSHDFRLQYDGQ--TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPD----------KNHVAPEFQATIEYVEC-DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFI--SEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPP-----------APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIVAKAQNEHGTAESRARLTV-EQEEEESRSAPTFLK 477 HSP 16 Score: 58.5362 bits (140), Expect = 1.756e-7 Identity = 40/179 (22.35%), Postives = 79/179 (44.13%), Query Frame = 2 Query: 9050 LSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIY-FIIKNLEEDDFGEYCA-----LDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRV 9568 + +K E+K + + W F + K D +++ G++ ++K D G+Y A + ++ + + PT + L + ++E ++SV + P P V W ++ + + + VI + + G+YS+ I L D G+Y+ RA N G A+ + N V Sbjct: 2087 VKEKEEIKMEVKVGGSAPDVEW-FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAV 2264 HSP 17 Score: 56.6102 bits (135), Expect = 5.907e-7 Identity = 39/138 (28.26%), Postives = 64/138 (46.38%), Query Frame = 2 Query: 5957 CGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP 6370 GKYT V N G + L+++ E + AP F L+D + E + L C+++ +PKPK+ W D +T+ + + V+ ++ T IT +E+ G+Y C+ N G TEA + V P Sbjct: 1846 AGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK-----APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESIT--VESVEGVERVT--ITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAP 1974 HSP 18 Score: 56.225 bits (134), Expect = 7.221e-7 Identity = 84/362 (23.20%), Postives = 144/362 (39.78%), Query Frame = 2 Query: 5327 GLYKCIVTNEKSETEF-----VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVE-SRVPTKSIDSAVWLKDEKLLNETDPRLTI-IMQPFCYNLILRDVKMTDAGMYSL-------KINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPN--FTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDS 6364 G+Y C+ NE + E VEI ++EK ++ +E+ + I LS + +P S+ VW KD L D R +I + L + D D G Y IN +S + VKV + ++K+ +E F K L D++ + ++ + V + W+ + + I+ S D +LT+ + G Y + N G ++ + + +E+ P F +L D+ + I L C++ P P + W+KDG L + R + +E + L I A V D G Y C+ TN G TT++ + + D Sbjct: 4233 GVYMCVAVNELGQAETQATYQVEILEHVEEEKRRE--YAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASV---VWYKDGLPLR-ADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTIN-TSCSVNVKVPKQEVKKEGEEPF-------FTKGLVDLWA-DRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL---IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDG 4576 HSP 19 Score: 55.8398 bits (133), Expect = 1.052e-6 Identity = 208/1044 (19.92%), Postives = 402/1044 (38.51%), Query Frame = 2 Query: 3362 WFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNV-LAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKP--IDSNIETC--PGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLL-IDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFE-----KDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIE---ITEGNELNLEV-VSEIEKDLQFQWSKDDIDCSNNGIFNSTK-NKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFI---------DLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPL 6409 W+ E + + V V+ES+ ++ + E+S +R+ FS E S V + K +S + + + G L L + + P K+ W+ N + I K E + K ++ IP+ ++ G +Y + E E K+ + P+I S L V + + E K+ G + K W+ N + + + K + + + LEI + Q+ D+ YK+ + +A L + K +KP + I T GE+ T V V+G K+ +KW K K + + K N + S+ L I + +L+D+ Y K ++S N + + VK K E+ + +E + W+ NG+ + SD + +L I + + Y+ ++ ++DGN++ + L V+ + + K +E ++ G+ + LE+ S K +++ + ++ + K + N + L + + D+G YK +E+ + N I T E ++ + + +++ + SVE N K +++W +N G ++ FI L I++ V + + YK ++ N E E ++TVK + + G + + + KI+ E WL+D +++ + + Y LI+ + DAG Y+++ INES K E+ + P+I + L++I I PE F+VE S + + W+ ++EI + + + L I A Y + ++N G S L+++ + + LKD+++ + + L ++ PK I W K+G+ L + + E F+L I ++ D G Y + N G + +V+ V ++ E S + PL Sbjct: 3032 WYKGTETVTSSQTTKIVQVTESEYKLEI--ESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP----KDVKWYKNGDEIKDGKV---EDLGNGKYRLTIPDFQEKDVG--EYSVTAANEAGEIESKAKVN---VSAKPEIV-----SGL------VPTTVKQGETATFNVKV-KGPVKGVK----WYKNGKEIPDAKTKDNGDGSYS-LEIPNAQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQ-VKW------YKNGKEIPNAKA--KDNGDGSYSLEIPNAQLDDTADY-------KVVVS------NDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEI-TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEP--KIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYK---------VEVANEAGSANSSGKI--TVEPKITFLKPLKDQSITEGENAEFSVET-NTKPRIVKWYKN----GQEIKPNSRFIIEQKTDTKYQLVIKN-AVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPED---------VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESG---------KAKSDAKGEVDEK---PEIVRGLENIEI---PEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLK------------IVDGLKDVDVEEPQPVELKVKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPL 3964 HSP 20 Score: 53.5286 bits (127), Expect = 4.589e-6 Identity = 128/612 (20.92%), Postives = 242/612 (39.54%), Query Frame = 2 Query: 4625 WFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNS-STARTELNVEN---IQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGM----VDGKLLEL-VHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGV-IQWLRNDMPFGDP---CVLDNPFIDLYIESPQVN-EHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVW-LKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRM-MCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPL 6409 W+ NG +LE + ++ IKN + L I N +S + E N+ G+S S+A+ +N + I +D SVT I+ TE E + ++ W+ ++ + + K ++ + L A+I +G K D K +L V V+ +S LT + + + +PL ++E+ G + WL N P V+D+ ++ + E SG N E E ++TV ++K E + T+E E ++ S + V K + + W L ++KL+ + ++ + + ++ ++ M G ++ S + + K + K ++P+ + D ++ E E VKF VE W E + +++ D + I A + G+ + + N +G + D +L++ + AP F K L+D I E ++ ++ + PKPKI W KDG + S + V+ +E + L I + ++ED GR + G A + V P + + + P+ Sbjct: 900 WYQNGNLLEDGKNGVT-IKNEENKSSLIIPNAQDSGKITVEA--SNEVGSSESSAQLTVNPPSTTPIVVDGPKSVT--IKETETAEFKATISGFPAPTVK--WTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLT-------------DKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNKKP------EFVQAPQNHETTLE-ESVKFS--AIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLK--------VDKKTEVPKFTTNMDDRQVK-EGEDVKFTANVEGYPEPSVAWTLNGEPV-SKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAV-----------KKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVE--EEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQSDIAPI 1459
BLAST of Serine/threonine kinase vs. Ensembl Celegans
Match: unc-89 (Muscle M-line assembly protein unc-89 [Source:UniProtKB/Swiss-Prot;Acc:O01761]) HSP 1 Score: 136.732 bits (343), Expect = 4.521e-31 Identity = 157/617 (25.45%), Postives = 269/617 (43.60%), Query Frame = 2 Query: 8714 ITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGI-------------GKPSMVIKKIRRSDN---LNSPTTEKA--MMLQEKHCLAVPMFC--------CLSQKAELKFTKLMEYKLDKITWTFNNAKVDVND--ERYKIFSAETYGIYFIIKNLEEDDFGEY-C-ALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTY--SLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPE-------KKSVQINIGDVNDRYYTMKK----LAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIY-----EKLQGLS-LAEYITQLSHWC----ESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHM--GL------TSP-FSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ--LYNEDS----NDAISN---SACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +TLSW P + +P Y T +E R + E+ WS+ + NI + + +L+ +YQ R+ +GI P V RR++ L P EKA M E++ A P F C + + I W F +D + + K+++ I +++ G+Y C A ++ D Q+ ++ + P + L N + + + + V++D +P PE+ W + W+ I S R +D G Y SL+I+ + D G YS A N G A + V+A + ++ V I V + Y +K A+G+ R V EK+T EF+ + I++ + + ++ H IV++ + D+ L L+ + GLS LA +++ E+ VR+ + QL+ A+ ++H+ R+ HLD++PE I++ ++ LKL DFG R + GL SP F +PE+++ P+ +DMWS G+LT++ L G + + D L N DS + + N A F++K L RLT ++L H W Sbjct: 5572 LTLSWIPTKRAPPRYPQVTYVIEIREL-----PEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAENIYGISDPSPASPPSRLMAPPQPVFD--RRTNKVIPLLDPYAEKALDMRYSEQYACA-PWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVGQYQCFAKNDYGDAQQNIMVDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQD---GPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTVTVEAEGDYNDVELPRRRVTIESRRVRELYEISEKDEKLAAEGAPFR---VKEKATGREFLAQLRPIDDALMRHVDIH--NSLDHPGIVQMHRVLR--DEKLALVVFDNANSTIDGLSSLAHPGVEIAEPKGVNRETCVRVFVRQLLLALKHMHDLRIAHLDLRPETILL---QDDKLKLA---------DFGQARRLLRGLITGEIKGSPEFVSPEIVRSYPLTLATDMWSTGVLTYVLLTGLSPFHGDNDNETLANVDSCQFDSSPLGNFSYDAGDFVKKLLTEIPVSRLTVDEALDHPWI 6158 HSP 2 Score: 92.0485 bits (227), Expect = 1.165e-17 Identity = 131/611 (21.44%), Postives = 246/611 (40.26%), Query Frame = 2 Query: 10622 PNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILN-ATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSP-----YLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRN-----IHSLKQALIFNRKWMLTSRQSNHFNDL--------------HDLIKDIS--SDDI-------------RMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFV-GTVKEQESLTTHKPSIFKAPEYRY-ESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNT--NTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPL 12319 P+ + E +K+D + P A + + + T +FT L+D + + A C +S S ++W ++L + R+ +E + ++ ILN A D+G + C A ++S RL+ G+ P +P + ++ E+ ++W YL I YR++ R + W T+ +D+ ++++L Y R+ AQN +G S+++ + Q + I LK + N M + +N + D+ ++ +DD R +VIR+ + ++ + AV ++ EY R + E++ L +F L E + +R F ++ Y+E V +RQ+ + FLH + H ++ P I+ ++ +S+ +KL+ Q V G VK + T + +PE+ E+ +SD+W +G+++F LLA P + + ++ V N + L+PV S+ F +LKKSP R D L+H + DP + E S++ L Sbjct: 6778 PSATAIERIKADIEKVTPCATKKN-DDGTFAPIFTARLRDVYLRKNQPA-----IFECAVS--ASPAPKVTWDFQGKILESNDRVTIE--QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPEGPTYLEGI---TYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIVQTHGKGAPKLQIDVLKSEIRLNVVSM-PQKSTNQLGGISEESEEDSEARTANEDMKSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAISEYESLRDGQHENVQ---RLIAAFNNSNFLYLLSERLYEDVFSRFVFNDY---------------YTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMF--QSKRSWVVKLVDFGRAQKVSGAVKPVDFDTK-----WASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDREEEIKENVINVKCDPNLIPV--------------NASQECLSFATWALKKSPVRRMRTDEALSHKFLSSDPSMVRRRESIKYSASRL 7335 HSP 3 Score: 84.3445 bits (207), Expect = 2.798e-15 Identity = 180/816 (22.06%), Postives = 331/816 (40.56%), Query Frame = 2 Query: 4013 QWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICF--NPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNN--NLSFLLIDSVKLEDSGTY--ICQGFTNKELISECKITLNVV---DNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEIL---EMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFN-STKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLR--NDMPFGDPCVL---DNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGEL-----LSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVD-----ILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETL--DSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTD 6361 +W+ N + + N K + + + LEI + QL D+ YK+ + +A +T + L IA I K L+ + E G+ L V+ K+IKW K K + Q ++ N L+I +D+ Y + S C +T+ + I L+ QV + I + + IE + + +V W+ NG+ L K+ + I +N + E+ ++ G Y+ + N+ G S+ + ++ VE +I L + K+ ITEG V + + + +W K+ + N F K + L A D+ YK +LE + + ++ K++ + +++ ++ V++ + V +WLR N + G ++ D+ L I S + + +G Y V NE K S GE+ + +E + E + VE P + + W K+++ + + P Y L + ++ D Y + ++ ++ D L V+P ++ I L+D+ + EP+ V+ + +VE G K I W+ +E+ DA+ +F + F+LTIP++ + G Y + + ND G V S G + + ++ SE + ++PL KD E+ + + L C + +P P+++W KDG L D + R LD TL I A+ D G+Y N G T++ + VT+ Sbjct: 3711 KWYKNGKEIPNAKAKDNGDGSYS-LEIPNAQLDDTADYKVVVSNDAGDADSSAALT-VKLPGIA-IVKGLE----DAEVPKGKKAVLQVETNK-KPKEIKW------YKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQV--------VSIGSPIKLE--IETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDT--GDYKVEVANEAG-SANSSGKITVEP-KITFLKPL-KDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKI-------VLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPEDV-RWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKD-AGEYTVEVINESG--------------KAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK---WYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLK--------------IVDGLKDVDV-EEPQPVELKVKVE--GIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYS-GSVVHVKSAKSSEPTSGANFLSPL-----KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVA--LDG--TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTE 4443 HSP 4 Score: 79.7221 bits (195), Expect = 6.186e-14 Identity = 167/756 (22.09%), Postives = 300/756 (39.68%), Query Frame = 2 Query: 4253 ESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNIS---DTLQCQVKFEKDKYSIEINQDVTMRALIECT---STHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNS-------STARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTV----QVNP-----IQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVL-----DNPFIDLYIESPQVNEHSGLYKCIVTNEKS-ETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDG-ETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKP 6406 E V L V G K + W L +K + ++ IT + + + I S +L G Y C N E S+ + L V D S DT + +F + S + + +A+++C + W G+ +EM + + ++ K++G + L N ++ G Y C EN+ G++ T ++ D L V + +T G LE + +W K+ + ++ + + LT A++ D Y+ E + G + V TV QV P + +I + K C+ +S +KP ++W ++ P + + D+ L IE + ++ G Y+ V+N+ V +TV V S L + + +VN + KI LSVE K++ W K + + + + + Y L + +M+D G Y + ++ ESS + V TK K + +P KK L D + P+ EVE G K + W+ +EI +E + + + LTIP EK G+Y++ AN+ G + S ++++ + EI ++ + + E N ++ P + W K+G E D+K + + +++L I A+VED+ Y + +N G + A + V K +D + VKP Sbjct: 3009 EKVVLECKVIGEPKPKVSW------LHDNKTITQESITVESVEGVERVTITSSELSHQGKYTCIA-ENTEGTSKTEAFLTVQDTASSKTDTGRGAPEFVELLRSCTVTE--KQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLT-LTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAV-VTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECK-----VSGTKP-------------DVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQ-GNYRIEVSNDAGVANSKVPLTV------VPSETLK--IKKGLTDVNVTQGTKILLSVEVEGKPKTVK---WYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTV----------TKAAEK-ISLPSFKKGLADQSV---PKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGKVEDL---GNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTT--------------VKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD------NGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTV-----KLADDGKDKVKP 3680 HSP 5 Score: 74.3294 bits (181), Expect = 2.540e-12 Identity = 62/273 (22.71%), Postives = 126/273 (46.15%), Query Frame = 2 Query: 9584 KKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQ--IEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPEL-LKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSACV-------FIRKCLLLKTG-------ERLTSSDSLSHEWF 10351 K ++Q+ D R+ KG +S + ++ +T+ K ++ I SE++ +++ H N+ + A +L L+ E+L + ++ ++ E QV + + Q+ A+ +LH + HLD+ P NI+ K + ++KL F A ++ G+ + + + +++PE + P+ SDMW +G++TF L G E D+ E+ + + N C ++CL T R+ + ++LSH++ Sbjct: 7051 KSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAI--SEYESLRDGQHENVQRLIAAFNN-SNFLYLLSERLYEDVFSRFVFN-DYYTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMFQSKRSWVVKLVDFGRA--QKVSGAVKPVDFDTKWASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDR--EEEIKENVINVKCDPNLIPVNASQECLSFATWALKKSPVRRMRTDEALSHKFL 7315 HSP 6 Score: 74.3294 bits (181), Expect = 2.929e-12 Identity = 169/795 (21.26%), Postives = 299/795 (37.61%), Query Frame = 2 Query: 4082 QLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAP-IKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTY-ICQGFTNKELISECKIT------LNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSD--ILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTA-----RTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMP--FGDPCVLDNPFIDLY-IESPQVNEHS-GLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELS----VESRVPTKSIDSAVWLKDEK---------LLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY-SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNF--TLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 +L I L D+G+Y + + S K V P I + L+ NIE G+ V+V ++ +KW + ++K + L+ K+I K L I+ +L+D Y + + S +T L +VD + D +E Q V ++ +E + W+ NG+ L+ +D + +G+ + L I + +S G Y ++ N G + ++ + E S K+ E+ EG+ L L+ E + W KD + ++ I L A+ +D G Y+ + G TV Q + + + + + D K +V+V + +QW N +P F D LD+ Y + V E G KCI NE E V +F+ + L + D +I + +E V W KD K + N D I + PF + +D G+Y + +NE I + +E + P+I PL+D + N + ++ +V+ +W+ + + A++ IQ+ D L I + E+ G Y N G + + S + ++ +Q ++ P FTK L D+ ++ L C + DP P+I W ++G+ L N +++ P+ +L + E+ + D G Y C N G T+A V Sbjct: 4116 RLIIPSADLKDAGEYTVEV--INESGKAKSDAKGEVDEKPEIVRGLE----NIEIPEGDDDVFKVEVSAPVRQ-VKWYKNDQEIKPNSHLEAKKIGPKKYE----LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDV------------DVEEPQPVELKVKVEGIPK--VIKWYKNGQELKPDADGFKFEEKPESGEFS-LTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQP----SKPKFVIPLKTGAALPGDKKEF--NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDETV---CEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPF---------EESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTV-NGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINT----SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL----RNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHV 4857 HSP 7 Score: 71.633 bits (174), Expect = 1.655e-11 Identity = 79/309 (25.57%), Postives = 132/309 (42.72%), Query Frame = 2 Query: 5534 WLKDEK---------LLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKI-LDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVT-DSEPKESDSSRIIVKPLCAPVLT 6427 WLKD K + T P I + L+L +V DAG Y+ + ++ + I K+ K K P+ LQD + E V E +V K W +N+ I E++ S + +TI ++ H GKYT N G +++ L++ + + ++ AP F + L+ + K+ L C++ +P+PKI WTK+G+ ++ ++ RV+ + TL D+G Y C N G TE IIVT + PK + ++P+ V+T Sbjct: 2920 WLKDGKEIELIARIRVQTRTGPEGHITQE-----LVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEK--KAPEFIVALQDKTTKTS-EKVVLECKVIGEPKPKVSWLHDNKTITQESITV--ESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQ---DTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVE---MSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVT 3212 HSP 8 Score: 70.8626 bits (172), Expect = 3.428e-11 Identity = 116/503 (23.06%), Postives = 200/503 (39.76%), Query Frame = 2 Query: 4919 WSKDDIDCSNN--GIFNSTKNKNCFNLTKLKAEITDSGVY------KFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDP----CVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFK-DEKVVSPILGELLSCTVEEVNTIEDEKIEL-SVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY----SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFE--NEEI--DAENMEFIQWSCDNYFALTIP-AAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 W KDD+ + F S ++ F +T ++TD+G Y ++ ++ + P + + C++ ++I EV W + + WL +D P D L I Q ++ +G+Y + NE E E+ V+ D+ V+P T+E V E E++ SV + P I +W + K L+E++ I C L ++DV GM S ++ +S D +KVR P P KPL+D ++ + V FEV+ SG + F +E+ E +E + D ++ ++IP + +KH G+ + N+ G S RL++ EQ E AP F K ++D + + E + +P P++ W +G +D VKI + L I A+ +G C N +G T+A ++V Sbjct: 581 WYKDDVQLHEDERHTFYSDED-GFFAMTIDPVQVTDTGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKE----CKEGDVI-------DFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPDD-TGVYTVKIQNEFGSIESKAELFVQADPDKNHVAP----EFQATIEYVECDEGEEVRFKSVITGDPNPEI---IWFINGKPLSESEKVKFISEDGICI-LTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPA------------PPTFNKPLEDKTVQEKSTVV---FEVDVSGWPEPTLTFTLCGKELKNGEEGVEIV--GHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV-------EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPG--VKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVV 1034 HSP 9 Score: 70.0922 bits (170), Expect = 4.672e-11 Identity = 225/1066 (21.11%), Postives = 428/1066 (40.15%), Query Frame = 2 Query: 3260 FFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKP--IDSNIETC--PGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLL-IDSVKLEDSGTY-ICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNG-EILEMKSDILSDIKNNGKIA-ELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKD--DIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFE-GMVDGKLLEL-VHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVL------DNPFIDLYIESPQVNEHSGLYKCIVTNEK-SETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFC---YNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF---IRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGY-DTTEAVIIV 6355 FF L I+ E + K D WF + L K + + + S + G ++ + + + ++ + V+ E + G D + + G + L++ + P T+K W+ +E + + + + E++ K+ I + E S YR+V + +S E + ++ K KI F+ L ++ + ++LE +I G K W+ N + +K+ + D + +L I Q D G+Y + A++ G++ S A + + KP + + T GE+ T V V+G K +KW K K + + + K N + S+ L I + ++ED+ Y + + S +T+ + D+ D ++ ++ +++ + T ++ V W+ NG EI K+ K+NG + L+I N Y+ ++ N G++ ++ L V+ I + + ++ E+ +G + L+V + +K + +W K+ +I S+ S + N L A D+ YK DG + TV+ L E ++ ED ++S P+ + +E + ++W +N ++P + DN ++ L I S V E +G YK V NE S +ITV+ K + P+ + ++ E E E SVE+ + + W K+ + E P I++ Y L++++ DA Y + + ESS + VK + K I K L+ + K + +F I+ EPE V+ W + I A I+ D + L IP+A K G+YT++V N+ G +SD + E+ E+ P + L++IEI ++ + P ++ W K+ + + KI + + L I A+++D Y + +N G D++ A+ +V Sbjct: 3300 FFKELSAIQVKETETAKFECKVSGTKPDV----KWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQ-----GTKILLSVEVEGKP-KTVK---WYKGTETVTSSQTTKIVQVTESEYKLEIESA--EMSDTGAYRVVLSTDSFSVESSATV--TVTKAAEKISLPSFKKGL------ADQSVPKGTPLVLEVEI-EGKPKDVK----WYKNGDEIKDGKVE-DLGNGKYRLTIPDFQEKDVGEYSVTA----ANEAGEIE-----SKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKW------YKNGKEIPDAKT--KDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQ--VKWYKNGKEIPNAKA------KDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSS-AALTVKLPGIAIVKGL-EDAEVPKGKKAVLQVETN-KKPKEIKWYKNGKEITPSDKAQPGSDGD-NKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVK-------LPAKEPKIIKGLEDQ--VVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV-LEIPS-SVVEDTGDYKVEVANEAGSANSSGKITVEPKI-TFLKPLKDQSIT---------EGENAEFSVETNTKPRIVK---WYKNGQ---EIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGAKMVFEVKIQGEPEDVR--------------WLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDA------KGEVDEK--------PEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPK--KYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4243 HSP 10 Score: 69.707 bits (169), Expect = 6.107e-11 Identity = 64/235 (27.23%), Postives = 105/235 (44.68%), Query Frame = 2 Query: 5792 EPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDG--------RLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFT--LIITEAEVEDSGRYCCLGTNFLGYDTT--EAVIIVTDSEPKESDSS-RIIVKPLCAPVLTAEYSKGADVI 6457 E + +K E +V+ S + +W+ + + + I S D L IP+ G Y + N G + G R S RS +++ + AP + L++I I K++ RL C+ DPKP I W KDGE + R++++ E P+ L++ A +D+G Y C+ N G T + +I D +P++ DSS R P LT +K D + Sbjct: 4994 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRS--ADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERV---FPYGRLQLI-ESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSV 5222 HSP 11 Score: 59.6918 bits (143), Expect = 6.445e-8 Identity = 94/384 (24.48%), Postives = 157/384 (40.89%), Query Frame = 2 Query: 5282 FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSP--ILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNET-DPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEI-DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVK 6403 F + I+ QV + +G Y C+ TNE + K EK +P + +L +E + I+ E VE P + VWL D++ L + D RL Q L +RD + D G+Y++KI ES ++ V+ P KN P+ + ++ + +E E V+F+ + + IWF + + ++E ++FI S D LTI G T Q +N +G DGRL + + P F K L+D + K + + P+P + +T G+ L + + D F ++ T + D G N G + A + V + E +ES S+ +K Sbjct: 603 FFAMTIDPVQVTD-TGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVID---FECEVEG-WPEPEL---VWLVDDQPLRPSHDFRLQYDGQ--TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPD----------KNHVAPEFQATIEYVEC-DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFI--SEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPP-----------APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIVAKAQNEHGTAESRARLTV-EQEEEESRSAPTFLK 950 HSP 12 Score: 56.225 bits (134), Expect = 7.480e-7 Identity = 206/1044 (19.73%), Postives = 399/1044 (38.22%), Query Frame = 2 Query: 3362 WFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNV-LAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKP--IDSNIETC--PGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLL-IDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFE-----KDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIE---ITEGNELNLEV-VSEIEKDLQFQWSKDDIDCSNNGIFNSTK-NKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFI---------DLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPL 6409 W+ E + + V V+ES+ ++ + E+S +R+ FS E S V + K +S + + + G L L + + P K+ W+ N + I K E + K ++ IP+ ++ G +Y + E E K+ + P+I S L V + + E K+ G + K W+ N + + + K + + + LEI + Q+ D+ YK+ + +A L + K +KP + I T GE+ T V V+G K+ +KW K K + + K N + S+ L I + +L+D+ Y + N + + VK K E+ + +E + W+ NG+ + SD + +L I + + Y+ ++ ++DGN++ + L V+ + + K +E ++ G+ + LE+ S K +++ + ++ + K + N + L + + D+G YK +E+ + N I T E ++ + + +++ + SVE N K +++W +N G ++ FI L I++ V + + YK ++ N E E ++TVK + + G + + + KI+ E WL+D +++ + + Y LI+ + DAG Y+++ INES K E+ + P+I + L++I I PE F+VE S + + W+ ++EI + + + L I A Y + ++N G S L+++ + + LKD+++ + + L ++ PK I W K+G+ L + + E F+L I ++ D G Y + N G + +V+ V ++ E S + PL Sbjct: 3425 WYKGTETVTSSQTTKIVQVTESEYKLEI--ESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP----KDVKWYKNGDEIKDGKV---EDLGNGKYRLTIPDFQEKDVG--EYSVTAANEAGEIESKAKVN---VSAKPEIV-----SGL------VPTTVKQGETATFNVKV-KGPVKGVK----WYKNGKEIPDAKTKDNGDGSYS-LEIPNAQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQ-VKW------YKNGKEIPNAKA--KDNGDGSYSLEIPNAQLDDTADYKV-------------VVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEI-TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEP--KIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYK---------VEVANEAGSANSSGKI--TVEPKITFLKPLKDQSITEGENAEFSVET-NTKPRIVKWYKN----GQEIKPNSRFIIEQKTDTKYQLVIKN-AVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPED---------VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESG---------KAKSDAKGEVDEK---PEIVRGLENIEI---PEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLK------------IVDGLKDVDVEEPQPVELKVKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPL 4357 HSP 13 Score: 55.8398 bits (133), Expect = 1.054e-6 Identity = 84/362 (23.20%), Postives = 144/362 (39.78%), Query Frame = 2 Query: 5327 GLYKCIVTNEKSETEF-----VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVE-SRVPTKSIDSAVWLKDEKLLNETDPRLTI-IMQPFCYNLILRDVKMTDAGMYSL-------KINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPN--FTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDS 6364 G+Y C+ NE + E VEI ++EK ++ +E+ + I LS + +P S+ VW KD L D R +I + L + D D G Y IN +S + VKV + ++K+ +E F K L D++ + ++ + V + W+ + + I+ S D +LT+ + G Y + N G ++ + + +E+ P F +L D+ + I L C++ P P + W+KDG L + R + +E + L I A V D G Y C+ TN G TT++ + + D Sbjct: 4626 GVYMCVAVNELGQAETQATYQVEILEHVEEEKRRE--YAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASV---VWYKDGLPLR-ADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTIN-TSCSVNVKVPKQEVKKEGEEPF-------FTKGLVDLWA-DRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL---IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDG 4969 HSP 14 Score: 53.9138 bits (128), Expect = 3.576e-6 Identity = 138/651 (21.20%), Postives = 257/651 (39.48%), Query Frame = 2 Query: 4472 ECKITLNVVDNISDTLQCQVKFEKDKYSIEINQ-DVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNS-STARTELNVEN---IQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGM----VDGKLLEL-VHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGV-IQWLRNDMPFGDP---CVLDNPFIDLYIESPQVN-EHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVW-LKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRM-MCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP 6370 E K L V++ +T + + F +E+ + D +I S Y W+ NG +LE + ++ IKN + L I N +S + E N+ G+S S+A+ +N + I +D SVT I+ TE E + ++ W+ ++ + + K ++ + L A+I +G K D K +L V V+ +S LT + + + +PL ++E+ G + WL N P V+D+ ++ + E SG N E E ++TV ++K E + T+E E ++ S + V K + + W L ++KL+ + ++ + + ++ ++ M G ++ S + + K + K ++P+ + D ++ E E VKF VE W E + +++ D + I A + G+ + + N +G + D +L++ + AP F K L+D I E ++ ++ + PKPKI W KDG + S + V+ +E + L I + ++ED GR + G A + V P Sbjct: 1965 ETKTELKVLETPKETKKPE--FTDKLRDMEVTKGDTVQMDVIALHSPLYK--WYQNGNLLEDGKNGVT-IKNEENKSSLIIPNAQDSGKITVEA--SNEVGSSESSAQLTVNPPSTTPIVVDGPKSVT--IKETETAEFKATISGFPAPTVK--WTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLT-------------DKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNKKP------EFVQAPQNHETTLE-ESVKFS--AIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLK--------VDKKTEVPKFTTNMDDRQVK-EGEDVKFTANVEGYPEPSVAWTLNGEPV-SKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAV-----------KKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVE--EEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRP 2559
BLAST of Serine/threonine kinase vs. Ensembl Celegans
Match: unc-89 (Muscle M-line assembly protein unc-89 [Source:UniProtKB/Swiss-Prot;Acc:O01761]) HSP 1 Score: 136.346 bits (342), Expect = 4.752e-31 Identity = 157/617 (25.45%), Postives = 269/617 (43.60%), Query Frame = 2 Query: 8714 ITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGI-------------GKPSMVIKKIRRSDN---LNSPTTEKA--MMLQEKHCLAVPMFC--------CLSQKAELKFTKLMEYKLDKITWTFNNAKVDVND--ERYKIFSAETYGIYFIIKNLEEDDFGEY-C-ALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTY--SLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPE-------KKSVQINIGDVNDRYYTMKK----LAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIY-----EKLQGLS-LAEYITQLSHWC----ESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHM--GL------TSP-FSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ--LYNEDS----NDAISN---SACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +TLSW P + +P Y T +E R + E+ WS+ + NI + + +L+ +YQ R+ +GI P V RR++ L P EKA M E++ A P F C + + I W F +D + + K+++ I +++ G+Y C A ++ D Q+ ++ + P + L N + + + + V++D +P PE+ W + W+ I S R +D G Y SL+I+ + D G YS A N G A + V+A + ++ V I V + Y +K A+G+ R V EK+T EF+ + I++ + + ++ H IV++ + D+ L L+ + GLS LA +++ E+ VR+ + QL+ A+ ++H+ R+ HLD++PE I++ ++ LKL DFG R + GL SP F +PE+++ P+ +DMWS G+LT++ L G + + D L N DS + + N A F++K L RLT ++L H W Sbjct: 6270 LTLSWIPTKRAPPRYPQVTYVIEIREL-----PEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAENIYGISDPSPASPPSRLMAPPQPVFD--RRTNKVIPLLDPYAEKALDMRYSEQYACA-PWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVGQYQCFAKNDYGDAQQNIMVDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQD---GPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTVTVEAEGDYNDVELPRRRVTIESRRVRELYEISEKDEKLAAEGAPFR---VKEKATGREFLAQLRPIDDALMRHVDIH--NSLDHPGIVQMHRVLR--DEKLALVVFDNANSTIDGLSSLAHPGVEIAEPKGVNRETCVRVFVRQLLLALKHMHDLRIAHLDLRPETILL---QDDKLKLA---------DFGQARRLLRGLITGEIKGSPEFVSPEIVRSYPLTLATDMWSTGVLTYVLLTGLSPFHGDNDNETLANVDSCQFDSSPLGNFSYDAGDFVKKLLTEIPVSRLTVDEALDHPWI 6856 HSP 2 Score: 98.5969 bits (244), Expect = 1.366e-19 Identity = 171/766 (22.32%), Postives = 303/766 (39.56%), Query Frame = 2 Query: 4283 GFSKKDIKWKVLEDDLKQDKILQE---KRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEM-KSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDD--IDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLK-LICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFI----------DLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDE-KLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INESSVDILV---KVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSC--DNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCI-----------------------APLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKI-LDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVT-DSEPKESDSSRIIVKPLCAPVLT 6427 G S D++W K DK + E + + + L++ D+G Y + +N +E V ++ + E ++IN+ T+ ++ SV W +G+ ++ S +++ ++ +G + + I++ G Y C N G + T V+N+ +E+ E L V + +W KDD I N + F+LT A D G+Y + G+ L +F + + I T +L+ L + E + D K +I V N ++W ++D P +DN I L I+ + E G+Y C TNE E + + V+ E++ +P+ + L E + + EL V RV K W KD + + + + + L+++D D G Y+ + N++ D V K+ KQT E K L I +PL++ F E +TV E +V + + I FF+N++ E + +Q D LTI A ++ G Y + N G ++ L + +++ E + + AP F + L+ + K+ L C++ +P+PKI WTK+G+ ++ ++ RV+ + TL D+G Y C N G TE IIVT + PK + ++P+ V+T Sbjct: 3191 GGSAPDVEW------FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKA-SNPAGTAESSAEAEVTQSLEKPTFVR---ELVTTEVKINETATLSVTVKGVPDP-SVEWLKDGQPVQTDSSHVIAKVEGSGSYS-ITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFT---QKLRPLEVREQETL--DLKVTVIGTPVPN-----VEWFKDDKPIN----IDNSHIFAKDEGSGHHTLTIKQAR-GEDVGVYTCKATNEAGEAKTTANMAVQ---EEIEAPLFVQGLKPYEVE----QGKPAELVV--RVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKPLFI----EPLKETFAV-EGDTVVLECKVNKE-SHPQIKFFKNDQ-PVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVE---MSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVT 3910 HSP 3 Score: 92.0485 bits (227), Expect = 1.263e-17 Identity = 131/611 (21.44%), Postives = 246/611 (40.26%), Query Frame = 2 Query: 10622 PNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILN-ATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSP-----YLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRN-----IHSLKQALIFNRKWMLTSRQSNHFNDL--------------HDLIKDIS--SDDI-------------RMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFV-GTVKEQESLTTHKPSIFKAPEYRY-ESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNT--NTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPL 12319 P+ + E +K+D + P A + + + T +FT L+D + + A C +S S ++W ++L + R+ +E + ++ ILN A D+G + C A ++S RL+ G+ P +P + ++ E+ ++W YL I YR++ R + W T+ +D+ ++++L Y R+ AQN +G S+++ + Q + I LK + N M + +N + D+ ++ +DD R +VIR+ + ++ + AV ++ EY R + E++ L +F L E + +R F ++ Y+E V +RQ+ + FLH + H ++ P I+ ++ +S+ +KL+ Q V G VK + T + +PE+ E+ +SD+W +G+++F LLA P + + ++ V N + L+PV S+ F +LKKSP R D L+H + DP + E S++ L Sbjct: 7476 PSATAIERIKADIEKVTPCATKKN-DDGTFAPIFTARLRDVYLRKNQPA-----IFECAVS--ASPAPKVTWDFQGKILESNDRVTIE--QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPEGPTYLEGI---TYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIVQTHGKGAPKLQIDVLKSEIRLNVVSM-PQKSTNQLGGISEESEEDSEARTANEDMKSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAISEYESLRDGQHENVQ---RLIAAFNNSNFLYLLSERLYEDVFSRFVFNDY---------------YTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMF--QSKRSWVVKLVDFGRAQKVSGAVKPVDFDTK-----WASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDREEEIKENVINVKCDPNLIPV--------------NASQECLSFATWALKKSPVRRMRTDEALSHKFLSSDPSMVRRRESIKYSASRL 8033 HSP 4 Score: 83.9593 bits (206), Expect = 3.378e-15 Identity = 180/816 (22.06%), Postives = 331/816 (40.56%), Query Frame = 2 Query: 4013 QWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICF--NPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNN--NLSFLLIDSVKLEDSGTY--ICQGFTNKELISECKITLNVV---DNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEIL---EMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFN-STKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLR--NDMPFGDPCVL---DNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGEL-----LSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVD-----ILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETL--DSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTD 6361 +W+ N + + N K + + + LEI + QL D+ YK+ + +A +T + L IA I K L+ + E G+ L V+ K+IKW K K + Q ++ N L+I +D+ Y + S C +T+ + I L+ QV + I + + IE + + +V W+ NG+ L K+ + I +N + E+ ++ G Y+ + N+ G S+ + ++ VE +I L + K+ ITEG V + + + +W K+ + N F K + L A D+ YK +LE + + ++ K++ + +++ ++ V++ + V +WLR N + G ++ D+ L I S + + +G Y V NE K S GE+ + +E + E + VE P + + W K+++ + + P Y L + ++ D Y + ++ ++ D L V+P ++ I L+D+ + EP+ V+ + +VE G K I W+ +E+ DA+ +F + F+LTIP++ + G Y + + ND G V S G + + ++ SE + ++PL KD E+ + + L C + +P P+++W KDG L D + R LD TL I A+ D G+Y N G T++ + VT+ Sbjct: 4409 KWYKNGKEIPNAKAKDNGDGSYS-LEIPNAQLDDTADYKVVVSNDAGDADSSAALT-VKLPGIA-IVKGLE----DAEVPKGKKAVLQVETNK-KPKEIKW------YKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQV--------VSIGSPIKLE--IETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDT--GDYKVEVANEAG-SANSSGKITVEP-KITFLKPL-KDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKI-------VLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPEDV-RWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKD-AGEYTVEVINESG--------------KAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK---WYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLK--------------IVDGLKDVDVE-EPQPVELKVKVE--GIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYS-GSVVHVKSAKSSEPTSGANFLSPL-----KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVA--LDG--TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTE 5141 HSP 5 Score: 74.3294 bits (181), Expect = 2.796e-12 Identity = 62/273 (22.71%), Postives = 127/273 (46.52%), Query Frame = 2 Query: 9584 KKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQ--IEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPEL-LKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSAC-------VFIRKCLLLKTG-------ERLTSSDSLSHEWF 10351 K ++Q+ D R+ KG +S + ++ +T+ K ++ I SE++ +++ H N+ + A + +L L+ E+L + ++ ++ E QV + + Q+ A+ +LH + HLD+ P NI+ K + ++KL F A ++ G+ + + + +++PE + P+ SDMW +G++TF L G E D+ E+ + + N C ++CL T R+ + ++LSH++ Sbjct: 7749 KSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAI--SEYESLRDGQHENVQRLIAAFNNSN-FLYLLSERLYEDVFSRFVFN-DYYTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMFQSKRSWVVKLVDFGRA--QKVSGAVKPVDFDTKWASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDR--EEEIKENVINVKCDPNLIPVNASQECLSFATWALKKSPVRRMRTDEALSHKFL 8013 HSP 6 Score: 73.559 bits (179), Expect = 4.284e-12 Identity = 169/795 (21.26%), Postives = 299/795 (37.61%), Query Frame = 2 Query: 4082 QLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAP-IKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTY-ICQGFTNKELISECKIT------LNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSD--ILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTA-----RTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMP--FGDPCVLDNPFIDLY-IESPQVNEHS-GLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELS----VESRVPTKSIDSAVWLKDEK---------LLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY-SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNF--TLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 +L I L D+G+Y + + S K V P I + L+ NIE G+ V+V ++ +KW + ++K + L+ K+I K L I+ +L+D Y + + S +T L +VD + D +E Q V ++ +E + W+ NG+ L+ +D + +G+ + L I + +S G Y ++ N G + ++ + E S K+ E+ EG+ L L+ E + W KD + ++ I L A+ +D G Y+ + G TV Q + + + + + D K +V+V + +QW N +P F D LD+ Y + V E G KCI NE E V +F+ + L + D +I + +E V W KD K + N D I + PF + +D G+Y + +NE I + +E + P+I PL+D + N + ++ +V+ +W+ + + A++ IQ+ D L I + E+ G Y N G + + S + ++ +Q ++ P FTK L D+ ++ L C + DP P+I W ++G+ L N +++ P+ +L + E+ + D G Y C N G T+A V Sbjct: 4814 RLIIPSADLKDAGEYTVEV--INESGKAKSDAKGEVDEKPEIVRGLE----NIEIPEGDDDVFKVEVSAPVRQ-VKWYKNDQEIKPNSHLEAKKIGPKKYE----LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDV------------DVEEPQPVELKVKVEGIPK--VIKWYKNGQELKPDADGFKFEEKPESGEFS-LTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQP----SKPKFVIPLKTGAALPGDKKEF--NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDETV---CEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPF---------EESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTV-NGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINT----SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL----RNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHV 5555 HSP 7 Score: 73.1738 bits (178), Expect = 6.788e-12 Identity = 200/875 (22.86%), Postives = 340/875 (38.86%), Query Frame = 2 Query: 3932 LNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCK---KDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSI---API-KKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNK----ELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIEC---TSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSST---------ARTELNV--ENIQI----------DCLNSVT-------------KNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNG-IFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISV---EVLNWK-----QGVIQWLRN--DMPFGDPCV---LDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSP-ILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTI-IMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSE-ISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVT 6358 L + E E + L+ +I + + +WF +D+ + N KD S L I + D G Y C EA + K T V AP+ + LKP E G+ L V VEG + ++KW +D + I + I +K N L+I D G Y CQ TNK E + E KI + + + E K + + D ++EC +H + +F N + +E+ + ++ +G I +L IQN + G Y C N G ++T A+ E +V E+ Q+ D +S T ++ +TE + L+ + E + +W+K+ + + + K+ LT D+G Y+ E E + + I+ T E K+ E + L KP +++V VL K + ++W +N ++ D LD+ L + + ++++ Y+C +NE + + ++T+ K+ V+P EL + V+E T K E V P W KD L E D R+ L++ D K D G Y +++ S D V P+ E K IKK L D+ N + K VE G K + W+ E + + I ++ + L I +A G Y + ++ D V S +++ +E IS P F K L D + + L + PK + W K+G+ + + +V+ L + L I + + +D G Y N G ++A + V+ Sbjct: 3469 LEVREQETLDLKVTVIGTPVPNV----EWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVY-TCKATNEAGEA-KTTANMAVQEEIEAPLFVQGLKPY----EVEQGKPAELVVRVEGKPEPEVKW--FKDGVPI-AIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQA-TNKAGKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDT---VVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI-KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEA-------ENEYGSAWTE--GPIIVTLEGAPKIDGEAPD-FLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMD-EYRCEASNEFGDV-WSDVTLTVKEPAQVAPGFFKELSAIQVKETETA---KFECKVSGTKP-----DVKWFKDGTPLKE-DKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEV---SNDAGVANSKVPLTVVPSETLK------IKKGLTDV---NVTQGTKILLSVEVEGKPKTVKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKIS---------LPSFKKGLADQSVPKGTPLVLEVEIEGKPK-DVKWYKNGDEIK----DGKVEDLGNG-KYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVS 4277 HSP 8 Score: 70.4774 bits (171), Expect = 3.868e-11 Identity = 116/503 (23.06%), Postives = 200/503 (39.76%), Query Frame = 2 Query: 4919 WSKDDIDCSNN--GIFNSTKNKNCFNLTKLKAEITDSGVY------KFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDP----CVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFK-DEKVVSPILGELLSCTVEEVNTIEDEKIEL-SVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY----SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFE--NEEI--DAENMEFIQWSCDNYFALTIP-AAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 W KDD+ + F S ++ F +T ++TD+G Y ++ ++ + P + + C++ ++I EV W + + WL +D P D L I Q ++ +G+Y + NE E E+ V+ D+ V+P T+E V E E++ SV + P I +W + K L+E++ I C L ++DV GM S ++ +S D +KVR P P KPL+D ++ + V FEV+ SG + F +E+ E +E + D ++ ++IP + +KH G+ + N+ G S RL++ EQ E AP F K ++D + + E + +P P++ W +G +D VKI + L I A+ +G C N +G T+A ++V Sbjct: 581 WYKDDVQLHEDERHTFYSDED-GFFAMTIDPVQVTDTGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKE----CKEGDVI-------DFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPDD-TGVYTVKIQNEFGSIESKAELFVQADPDKNHVAP----EFQATIEYVECDEGEEVRFKSVITGDPNPEI---IWFINGKPLSESEKVKFISEDGICI-LTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP------------PTFNKPLEDKTVQEKSTVV---FEVDVSGWPEPTLTFTLCGKELKNGEEGVEIV--GHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV-------EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPG--VKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVV 1034 HSP 9 Score: 69.707 bits (169), Expect = 6.390e-11 Identity = 64/235 (27.23%), Postives = 105/235 (44.68%), Query Frame = 2 Query: 5792 EPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDG--------RLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFT--LIITEAEVEDSGRYCCLGTNFLGYDTT--EAVIIVTDSEPKESDSS-RIIVKPLCAPVLTAEYSKGADVI 6457 E + +K E +V+ S + +W+ + + + I S D L IP+ G Y + N G + G R S RS +++ + AP + L++I I K++ RL C+ DPKP I W KDGE + R++++ E P+ L++ A +D+G Y C+ N G T + +I D +P++ DSS R P LT +K D + Sbjct: 5692 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRS--ADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERV---FPYGRLQLI-ESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSV 5920 HSP 10 Score: 69.707 bits (169), Expect = 6.608e-11 Identity = 225/1066 (21.11%), Postives = 428/1066 (40.15%), Query Frame = 2 Query: 3260 FFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKP--IDSNIETC--PGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLL-IDSVKLEDSGTY-ICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNG-EILEMKSDILSDIKNNGKIA-ELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKD--DIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFE-GMVDGKLLEL-VHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVL------DNPFIDLYIESPQVNEHSGLYKCIVTNEK-SETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFC---YNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF---IRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGY-DTTEAVIIV 6355 FF L I+ E + K D WF + L K + + + S + G ++ + + + ++ + V+ E + G D + + G + L++ + P T+K W+ +E + + + + E++ K+ I + E S YR+V + +S E + ++ K KI F+ L ++ + ++LE +I G K W+ N + +K+ + D + +L I Q D G+Y + A++ G++ S A + + KP + + T GE+ T V V+G K +KW K K + + + K N + S+ L I + ++ED+ Y + + S +T+ + D+ D ++ ++ +++ + T ++ V W+ NG EI K+ K+NG + L+I N Y+ ++ N G++ ++ L V+ I + + ++ E+ +G + L+V + +K + +W K+ +I S+ S + N L A D+ YK DG + TV+ L E ++ ED ++S P+ + +E + ++W +N ++P + DN ++ L I S V E +G YK V NE S +ITV+ K + P+ + ++ E E E SVE+ + + W K+ + E P I++ Y L++++ DA Y + + ESS + VK + K I K L+ + K + +F I+ EPE V+ W + I A I+ D + L IP+A K G+YT++V N+ G +SD + E+ E+ P + L++IEI ++ + P ++ W K+ + + KI + + L I A+++D Y + +N G D++ A+ +V Sbjct: 3998 FFKELSAIQVKETETAKFECKVSGTKPDV----KWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQ-----GTKILLSVEVEGKP-KTVK---WYKGTETVTSSQTTKIVQVTESEYKLEIESA--EMSDTGAYRVVLSTDSFSVESSATV--TVTKAAEKISLPSFKKGL------ADQSVPKGTPLVLEVEI-EGKPKDVK----WYKNGDEIKDGKVE-DLGNGKYRLTIPDFQEKDVGEYSVTA----ANEAGEIE-----SKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKW------YKNGKEIPDAKT--KDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQ--VKWYKNGKEIPNAKA------KDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSS-AALTVKLPGIAIVKGL-EDAEVPKGKKAVLQVETN-KKPKEIKWYKNGKEITPSDKAQPGSDGD-NKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVK-------LPAKEPKIIKGLEDQ--VVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV-LEIPS-SVVEDTGDYKVEVANEAGSANSSGKITVEPKI-TFLKPLKDQSIT---------EGENAEFSVETNTKPRIVK---WYKNGQ---EIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGAKMVFEVKIQGEPEDVR--------------WLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDA------KGEVDEK--------PEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPK--KYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4941 HSP 11 Score: 69.3218 bits (168), Expect = 9.234e-11 Identity = 157/732 (21.45%), Postives = 287/732 (39.21%), Query Frame = 2 Query: 4394 LLIDSVKLEDSGTYICQGF-------TNKELISE--CKITLNVVD------------NISDTLQCQVKFEKDKYS-IEINQDVTM----RALIECT---STHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNS-------STARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTV----QVNP-----IQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVL-----DNPFIDLYIESPQVNEHSGLYKCIVTNEKS-ETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDG-ETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKP 6406 L I + K ED G Y C+ TN +L + K+ +V D + DT + + +E+ + T+ +A+++C + W G+ +EM + + ++ K++G + L N ++ G Y C EN+ G++ T ++ D L V + +T G LE + +W K+ + ++ + + LT A++ D Y+ E + G + V TV QV P + +I + K C+ +S +KP + +W ++ P + + D+ L IE + ++ G Y+ V+N+ V +TV V S L + + +VN + KI LSVE K++ W K + + + + + Y L + +M+D G Y + ++ ESS + V TK K + +P KK L D + P+ EVE G K + W+ +EI +E + + + LTIP EK G+Y++ AN+ G + S ++++ + EI ++ + + E N ++ P + W K+G E D+K + + +++L I A+VED+ Y + +N G + A + V K +D + VKP Sbjct: 3722 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLT-LTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAV-VTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECK-----VSGTKPDV-------------KWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQ-GNYRIEVSNDAGVANSKVPLTV------VPSETL--KIKKGLTDVNVTQGTKILLSVEVEGKPKTVK---WYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTV----------TKAAEK-ISLPSFKKGLADQSV---PKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGKVEDL---GNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTT--------------VKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD------NGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTV-----KLADDGKDKVKP 4378 HSP 12 Score: 66.2402 bits (160), Expect = 6.821e-10 Identity = 85/362 (23.48%), Postives = 148/362 (40.88%), Query Frame = 2 Query: 5333 YKCIVTNE-KSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP--FCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFI-QWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDE---FPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVI-IVTDSEPKE 6376 YK I TN + T +IT K V +P+ + L T V E+ K+E+ V P W KD+K ++E D + P + L+++ TDAG Y+ K + ESS + E+ ++L+ P + L ++ ET V+ W + + + ++ I + +++TI A + GKY + N G +++ +++ + P F +KL +E+ KE+ L+ +++ P+P + W KD D+ V ++ + +F+L I +A D G Y C N G T A I+ DS P E Sbjct: 3143 YKAIATNSIGTATSTSKITTK-----VEAPVFEQGLKKT--SVKEKEEIKMEVKVGGSAP-----DVEWFKDDKPVSE-DGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEA--------------EVTQSLEKPTFVRELVTTEVKIN-ETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVV-----------KNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKD----DTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPE 3461 HSP 13 Score: 64.6994 bits (156), Expect = 2.075e-9 Identity = 172/819 (21.00%), Postives = 296/819 (36.14%), Query Frame = 2 Query: 4085 LEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKPID-----SNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSF-LLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHY-SVSWFFNGEILEM-KSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS--NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGM-VDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMP--FGDPC---VLDNPFIDLYIESPQVNEHSGLYKCIVTN-------------------------------EKSETEFVEITVKFK-DEKVVSPILGELL-SCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKI--------NESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILD-EFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSE 6367 + I +L DSG+Y C A + +V KNL P + S +E ES TL V V G + ++W + + D + + QK SF L I+ + D G Y C+ + E T N I D++ + F + +E+ + T+ + T +V WF + + + + S I + + +G L I+ G+Y C N+ G + T E I+ K E+ +G L V E + + + +W KD + + N + L D G Y + GK + + + T +E + I E + +++ +V I++ +ND P G VL++ I L I++ + E G Y+C N E + E V T K D +P ELL SCTV E K + ++ +V + W K+ K + + L +V DAG Y + E + + ++ PK + + P +P++ + ET E ++ W+ EE+ + I+ D LT+ A +Y + +N+ G V SD L++ E +AP F K+L I++ E + C+ + KP + W KDG L ++RV + L+I +++ +D G Y +N G ++ + V SE Sbjct: 3323 ITIKDARLEDSGKY-ACRATNPAGEAKTEANFAVV------KNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNV----HVIQKQTAVGSFSLTINDARQGDVGIYSCRA---RNEAGEALTTANF-GIIRDSIPPE--FTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHT-LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEK-QTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNAK-KEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTE-------KQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPK----------IDGEAPDFLQPVKPAVV-TVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVK----------EPAQVAPGFFKELSAIQVKETETAKFECK-VSGTKPDVKWFKDGTPLKE---DKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSE 4089 HSP 14 Score: 59.6918 bits (143), Expect = 7.207e-8 Identity = 94/384 (24.48%), Postives = 157/384 (40.89%), Query Frame = 2 Query: 5282 FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSP--ILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNET-DPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEI-DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVK 6403 F + I+ QV + +G Y C+ TNE + K EK +P + +L +E + I+ E VE P + VWL D++ L + D RL Q L +RD + D G+Y++KI ES ++ V+ P KN P+ + ++ + +E E V+F+ + + IWF + + ++E ++FI S D LTI G T Q +N +G DGRL + + P F K L+D + K + + P+P + +T G+ L + + D F ++ T + D G N G + A + V + E +ES S+ +K Sbjct: 603 FFAMTIDPVQVTD-TGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVID---FECEVEG-WPEPEL---VWLVDDQPLRPSHDFRLQYDGQ--TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPD----------KNHVAPEFQATIEYVEC-DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFI--SEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPP-----------APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIVAKAQNEHGTAESRARLTV-EQEEEESRSAPTFLK 950 HSP 15 Score: 58.5362 bits (140), Expect = 1.824e-7 Identity = 40/181 (22.10%), Postives = 79/181 (43.65%), Query Frame = 2 Query: 9044 CCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIY-FIIKNLEEDDFGEYCA-----LDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRV 9568 + +K E+K + + W F + K D +++ G++ ++K D G+Y A + ++ + + PT + L + ++E ++SV + P P V W ++ + + + VI + + G+YS+ I L D G+Y+ RA N G A+ + N V Sbjct: 3176 TSVKEKEEIKMEVKVGGSAPDVEW-FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAV 3355 HSP 16 Score: 56.9954 bits (136), Expect = 4.428e-7 Identity = 39/138 (28.26%), Postives = 64/138 (46.38%), Query Frame = 2 Query: 5957 CGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP 6370 GKYT V N G + L+++ E + AP F L+D + E + L C+++ +PKPK+ W D +T+ + + V+ ++ T IT +E+ G+Y C+ N G TEA + V P Sbjct: 2937 AGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK-----APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESIT--VESVEGVERVT--ITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAP 3065 HSP 17 Score: 55.8398 bits (133), Expect = 1.198e-6 Identity = 84/362 (23.20%), Postives = 144/362 (39.78%), Query Frame = 2 Query: 5327 GLYKCIVTNEKSETEF-----VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVE-SRVPTKSIDSAVWLKDEKLLNETDPRLTI-IMQPFCYNLILRDVKMTDAGMYSL-------KINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPN--FTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDS 6364 G+Y C+ NE + E VEI ++EK ++ +E+ + I LS + +P S+ VW KD L D R +I + L + D D G Y IN +S + VKV + ++K+ +E F K L D++ + ++ + V + W+ + + I+ S D +LT+ + G Y + N G ++ + + +E+ P F +L D+ + I L C++ P P + W+KDG L + R + +E + L I A V D G Y C+ TN G TT++ + + D Sbjct: 5324 GVYMCVAVNELGQAETQATYQVEILEHVEEEKRRE--YAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASV---VWYKDGLPLR-ADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTIN-TSCSVNVKVPKQEVKKEGEEPF-------FTKGLVDLWA-DRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL---IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDG 5667 HSP 18 Score: 55.4546 bits (132), Expect = 1.229e-6 Identity = 206/1044 (19.73%), Postives = 399/1044 (38.22%), Query Frame = 2 Query: 3362 WFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNV-LAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKP--IDSNIETC--PGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLL-IDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFE-----KDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIE---ITEGNELNLEV-VSEIEKDLQFQWSKDDIDCSNNGIFNSTK-NKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFI---------DLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPL 6409 W+ E + + V V+ES+ ++ + E+S +R+ FS E S V + K +S + + + G L L + + P K+ W+ N + I K E + K ++ IP+ ++ G +Y + E E K+ + P+I S L V + + E K+ G + K W+ N + + + K + + + LEI + Q+ D+ YK+ + +A L + K +KP + I T GE+ T V V+G K+ +KW K K + + K N + S+ L I + +L+D+ Y + N + + VK K E+ + +E + W+ NG+ + SD + +L I + + Y+ ++ ++DGN++ + L V+ + + K +E ++ G+ + LE+ S K +++ + ++ + K + N + L + + D+G YK +E+ + N I T E ++ + + +++ + SVE N K +++W +N G ++ FI L I++ V + + YK ++ N E E ++TVK + + G + + + KI+ E WL+D +++ + + Y LI+ + DAG Y+++ INES K E+ + P+I + L++I I PE F+VE S + + W+ ++EI + + + L I A Y + ++N G S L+++ + + LKD+++ + + L ++ PK I W K+G+ L + + E F+L I ++ D G Y + N G + +V+ V ++ E S + PL Sbjct: 4123 WYKGTETVTSSQTTKIVQVTESEYKLEI--ESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP----KDVKWYKNGDEIKDGKV---EDLGNGKYRLTIPDFQEKDVG--EYSVTAANEAGEIESKAKVN---VSAKPEIV-----SGL------VPTTVKQGETATFNVKV-KGPVKGVK----WYKNGKEIPDAKTKDNGDGSYS-LEIPNAQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQ-VKW------YKNGKEIPNAKA--KDNGDGSYSLEIPNAQLDDTADYKV-------------VVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEI-TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEP--KIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYK---------VEVANEAGSANSSGKI--TVEPKITFLKPLKDQSITEGENAEFSVET-NTKPRIVKWYKN----GQEIKPNSRFIIEQKTDTKYQLVIKN-AVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPED---------VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESG---------KAKSDAKGEVDEK---PEIVRGLENIEI---PEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLK------------IVDGLKDVDVEEPQPVELKVKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPL 5055 HSP 19 Score: 53.9138 bits (128), Expect = 4.274e-6 Identity = 138/651 (21.20%), Postives = 257/651 (39.48%), Query Frame = 2 Query: 4472 ECKITLNVVDNISDTLQCQVKFEKDKYSIEINQ-DVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNS-STARTELNVEN---IQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGM----VDGKLLEL-VHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGV-IQWLRNDMPFGDP---CVLDNPFIDLYIESPQVN-EHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVW-LKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRM-MCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP 6370 E K L V++ +T + + F +E+ + D +I S Y W+ NG +LE + ++ IKN + L I N +S + E N+ G+S S+A+ +N + I +D SVT I+ TE E + ++ W+ ++ + + K ++ + L A+I +G K D K +L V V+ +S LT + + + +PL ++E+ G + WL N P V+D+ ++ + E SG N E E ++TV ++K E + T+E E ++ S + V K + + W L ++KL+ + ++ + + ++ ++ M G ++ S + + K + K ++P+ + D ++ E E VKF VE W E + +++ D + I A + G+ + + N +G + D +L++ + AP F K L+D I E ++ ++ + PKPKI W KDG + S + V+ +E + L I + ++ED GR + G A + V P Sbjct: 1943 ETKTELKVLETPKETKKPE--FTDKLRDMEVTKGDTVQMDVIALHSPLYK--WYQNGNLLEDGKNGVT-IKNEENKSSLIIPNAQDSGKITVEA--SNEVGSSESSAQLTVNPPSTTPIVVDGPKSVT--IKETETAEFKATISGFPAPTVK--WTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLT-------------DKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNKKP------EFVQAPQNHETTLE-ESVKFS--AIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLK--------VDKKTEVPKFTTNMDDRQVK-EGEDVKFTANVEGYPEPSVAWTLNGEPV-SKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAV-----------KKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVE--EEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRP 2537
BLAST of Serine/threonine kinase vs. Ensembl Celegans
Match: unc-89 (Muscle M-line assembly protein unc-89 [Source:UniProtKB/Swiss-Prot;Acc:O01761]) HSP 1 Score: 136.346 bits (342), Expect = 5.082e-31 Identity = 157/617 (25.45%), Postives = 269/617 (43.60%), Query Frame = 2 Query: 8714 ITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGI-------------GKPSMVIKKIRRSDN---LNSPTTEKA--MMLQEKHCLAVPMFC--------CLSQKAELKFTKLMEYKLDKITWTFNNAKVDVND--ERYKIFSAETYGIYFIIKNLEEDDFGEY-C-ALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTY--SLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPE-------KKSVQINIGDVNDRYYTMKK----LAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIY-----EKLQGLS-LAEYITQLSHWC----ESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHM--GL------TSP-FSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ--LYNEDS----NDAISN---SACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +TLSW P + +P Y T +E R + E+ WS+ + NI + + +L+ +YQ R+ +GI P V RR++ L P EKA M E++ A P F C + + I W F +D + + K+++ I +++ G+Y C A ++ D Q+ ++ + P + L N + + + + V++D +P PE+ W + W+ I S R +D G Y SL+I+ + D G YS A N G A + V+A + ++ V I V + Y +K A+G+ R V EK+T EF+ + I++ + + ++ H IV++ + D+ L L+ + GLS LA +++ E+ VR+ + QL+ A+ ++H+ R+ HLD++PE I++ ++ LKL DFG R + GL SP F +PE+++ P+ +DMWS G+LT++ L G + + D L N DS + + N A F++K L RLT ++L H W Sbjct: 6292 LTLSWIPTKRAPPRYPQVTYVIEIREL-----PEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAENIYGISDPSPASPPSRLMAPPQPVFD--RRTNKVIPLLDPYAEKALDMRYSEQYACA-PWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVGQYQCFAKNDYGDAQQNIMVDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQD---GPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTVTVEAEGDYNDVELPRRRVTIESRRVRELYEISEKDEKLAAEGAPFR---VKEKATGREFLAQLRPIDDALMRHVDIH--NSLDHPGIVQMHRVLR--DEKLALVVFDNANSTIDGLSSLAHPGVEIAEPKGVNRETCVRVFVRQLLLALKHMHDLRIAHLDLRPETILL---QDDKLKLA---------DFGQARRLLRGLITGEIKGSPEFVSPEIVRSYPLTLATDMWSTGVLTYVLLTGLSPFHGDNDNETLANVDSCQFDSSPLGNFSYDAGDFVKKLLTEIPVSRLTVDEALDHPWI 6878 HSP 2 Score: 98.2117 bits (243), Expect = 1.656e-19 Identity = 171/766 (22.32%), Postives = 303/766 (39.56%), Query Frame = 2 Query: 4283 GFSKKDIKWKVLEDDLKQDKILQE---KRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEM-KSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDD--IDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLK-LICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFI----------DLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDE-KLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INESSVDILV---KVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSC--DNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCI-----------------------APLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKI-LDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVT-DSEPKESDSSRIIVKPLCAPVLT 6427 G S D++W K DK + E + + + L++ D+G Y + +N +E V ++ + E ++IN+ T+ ++ SV W +G+ ++ S +++ ++ +G + + I++ G Y C N G + T V+N+ +E+ E L V + +W KDD I N + F+LT A D G+Y + G+ L +F + + I T +L+ L + E + D K +I V N ++W ++D P +DN I L I+ + E G+Y C TNE E + + V+ E++ +P+ + L E + + EL V RV K W KD + + + + + L+++D D G Y+ + N++ D V K+ KQT E K L I +PL++ F E +TV E +V + + I FF+N++ E + +Q D LTI A ++ G Y + N G ++ L + +++ E + + AP F + L+ + K+ L C++ +P+PKI WTK+G+ ++ ++ RV+ + TL D+G Y C N G TE IIVT + PK + ++P+ V+T Sbjct: 3213 GGSAPDVEW------FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKA-SNPAGTAESSAEAEVTQSLEKPTFVR---ELVTTEVKINETATLSVTVKGVPDP-SVEWLKDGQPVQTDSSHVIAKVEGSGSYS-ITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFT---QKLRPLEVREQETL--DLKVTVIGTPVPN-----VEWFKDDKPIN----IDNSHIFAKDEGSGHHTLTIKQAR-GEDVGVYTCKATNEAGEAKTTANMAVQ---EEIEAPLFVQGLKPYEVE----QGKPAELVV--RVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKPLFI----EPLKETFAV-EGDTVVLECKVNKE-SHPQIKFFKNDQ-PVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVE---MSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVT 3932 HSP 3 Score: 92.0485 bits (227), Expect = 1.252e-17 Identity = 131/611 (21.44%), Postives = 246/611 (40.26%), Query Frame = 2 Query: 10622 PNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILN-ATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSP-----YLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRN-----IHSLKQALIFNRKWMLTSRQSNHFNDL--------------HDLIKDIS--SDDI-------------RMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFV-GTVKEQESLTTHKPSIFKAPEYRY-ESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNT--NTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPL 12319 P+ + E +K+D + P A + + + T +FT L+D + + A C +S S ++W ++L + R+ +E + ++ ILN A D+G + C A ++S RL+ G+ P +P + ++ E+ ++W YL I YR++ R + W T+ +D+ ++++L Y R+ AQN +G S+++ + Q + I LK + N M + +N + D+ ++ +DD R +VIR+ + ++ + AV ++ EY R + E++ L +F L E + +R F ++ Y+E V +RQ+ + FLH + H ++ P I+ ++ +S+ +KL+ Q V G VK + T + +PE+ E+ +SD+W +G+++F LLA P + + ++ V N + L+PV S+ F +LKKSP R D L+H + DP + E S++ L Sbjct: 7498 PSATAIERIKADIEKVTPCATKKN-DDGTFAPIFTARLRDVYLRKNQPA-----IFECAVS--ASPAPKVTWDFQGKILESNDRVTIE--QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPEGPTYLEGI---TYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIVQTHGKGAPKLQIDVLKSEIRLNVVSM-PQKSTNQLGGISEESEEDSEARTANEDMKSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAISEYESLRDGQHENVQ---RLIAAFNNSNFLYLLSERLYEDVFSRFVFNDY---------------YTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMF--QSKRSWVVKLVDFGRAQKVSGAVKPVDFDTK-----WASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDREEEIKENVINVKCDPNLIPV--------------NASQECLSFATWALKKSPVRRMRTDEALSHKFLSSDPSMVRRRESIKYSASRL 8055 HSP 4 Score: 83.5741 bits (205), Expect = 4.096e-15 Identity = 180/816 (22.06%), Postives = 331/816 (40.56%), Query Frame = 2 Query: 4013 QWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICF--NPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNN--NLSFLLIDSVKLEDSGTY--ICQGFTNKELISECKITLNVV---DNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEIL---EMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFN-STKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLR--NDMPFGDPCVL---DNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGEL-----LSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVD-----ILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETL--DSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTD 6361 +W+ N + + N K + + + LEI + QL D+ YK+ + +A +T + L IA I K L+ + E G+ L V+ K+IKW K K + Q ++ N L+I +D+ Y + S C +T+ + I L+ QV + I + + IE + + +V W+ NG+ L K+ + I +N + E+ ++ G Y+ + N+ G S+ + ++ VE +I L + K+ ITEG V + + + +W K+ + N F K + L A D+ YK +LE + + ++ K++ + +++ ++ V++ + V +WLR N + G ++ D+ L I S + + +G Y V NE K S GE+ + +E + E + VE P + + W K+++ + + P Y L + ++ D Y + ++ ++ D L V+P ++ I L+D+ + EP+ V+ + +VE G K I W+ +E+ DA+ +F + F+LTIP++ + G Y + + ND G V S G + + ++ SE + ++PL KD E+ + + L C + +P P+++W KDG L D + R LD TL I A+ D G+Y N G T++ + VT+ Sbjct: 4431 KWYKNGKEIPNAKAKDNGDGSYS-LEIPNAQLDDTADYKVVVSNDAGDADSSAALT-VKLPGIA-IVKGLE----DAEVPKGKKAVLQVETNK-KPKEIKW------YKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQV--------VSIGSPIKLE--IETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDT--GDYKVEVANEAG-SANSSGKITVEP-KITFLKPL-KDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKI-------VLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPEDV-RWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKD-AGEYTVEVINESG--------------KAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK---WYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLK--------------IVDGLKDVDVE-EPQPVELKVKVE--GIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYS-GSVVHVKSAKSSEPTSGANFLSPL-----KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVA--LDG--TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTE 5163 HSP 5 Score: 74.3294 bits (181), Expect = 2.916e-12 Identity = 62/273 (22.71%), Postives = 127/273 (46.52%), Query Frame = 2 Query: 9584 KKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQ--IEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPEL-LKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSAC-------VFIRKCLLLKTG-------ERLTSSDSLSHEWF 10351 K ++Q+ D R+ KG +S + ++ +T+ K ++ I SE++ +++ H N+ + A + +L L+ E+L + ++ ++ E QV + + Q+ A+ +LH + HLD+ P NI+ K + ++KL F A ++ G+ + + + +++PE + P+ SDMW +G++TF L G E D+ E+ + + N C ++CL T R+ + ++LSH++ Sbjct: 7771 KSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAI--SEYESLRDGQHENVQRLIAAFNNSN-FLYLLSERLYEDVFSRFVFN-DYYTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMFQSKRSWVVKLVDFGRA--QKVSGAVKPVDFDTKWASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDR--EEEIKENVINVKCDPNLIPVNASQECLSFATWALKKSPVRRMRTDEALSHKFL 8035 HSP 6 Score: 73.559 bits (179), Expect = 4.543e-12 Identity = 169/795 (21.26%), Postives = 299/795 (37.61%), Query Frame = 2 Query: 4082 QLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAP-IKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTY-ICQGFTNKELISECKIT------LNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSD--ILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTA-----RTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMP--FGDPCVLDNPFIDLY-IESPQVNEHS-GLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELS----VESRVPTKSIDSAVWLKDEK---------LLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY-SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNF--TLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 +L I L D+G+Y + + S K V P I + L+ NIE G+ V+V ++ +KW + ++K + L+ K+I K L I+ +L+D Y + + S +T L +VD + D +E Q V ++ +E + W+ NG+ L+ +D + +G+ + L I + +S G Y ++ N G + ++ + E S K+ E+ EG+ L L+ E + W KD + ++ I L A+ +D G Y+ + G TV Q + + + + + D K +V+V + +QW N +P F D LD+ Y + V E G KCI NE E V +F+ + L + D +I + +E V W KD K + N D I + PF + +D G+Y + +NE I + +E + P+I PL+D + N + ++ +V+ +W+ + + A++ IQ+ D L I + E+ G Y N G + + S + ++ +Q ++ P FTK L D+ ++ L C + DP P+I W ++G+ L N +++ P+ +L + E+ + D G Y C N G T+A V Sbjct: 4836 RLIIPSADLKDAGEYTVEV--INESGKAKSDAKGEVDEKPEIVRGLE----NIEIPEGDDDVFKVEVSAPVRQ-VKWYKNDQEIKPNSHLEAKKIGPKKYE----LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDV------------DVEEPQPVELKVKVEGIPK--VIKWYKNGQELKPDADGFKFEEKPESGEFS-LTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQP----SKPKFVIPLKTGAALPGDKKEF--NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDETV---CEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPF---------EESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTV-NGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINT----SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL----RNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHV 5577 HSP 7 Score: 72.7886 bits (177), Expect = 8.092e-12 Identity = 200/875 (22.86%), Postives = 340/875 (38.86%), Query Frame = 2 Query: 3932 LNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCK---KDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSI---API-KKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNK----ELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIEC---TSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSST---------ARTELNV--ENIQI----------DCLNSVT-------------KNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNG-IFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISV---EVLNWK-----QGVIQWLRN--DMPFGDPCV---LDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSP-ILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTI-IMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSE-ISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVT 6358 L + E E + L+ +I + + +WF +D+ + N KD S L I + D G Y C EA + K T V AP+ + LKP E G+ L V VEG + ++KW +D + I + I +K N L+I D G Y CQ TNK E + E KI + + + E K + + D ++EC +H + +F N + +E+ + ++ +G I +L IQN + G Y C N G ++T A+ E +V E+ Q+ D +S T ++ +TE + L+ + E + +W+K+ + + + K+ LT D+G Y+ E E + + I+ T E K+ E + L KP +++V VL K + ++W +N ++ D LD+ L + + ++++ Y+C +NE + + ++T+ K+ V+P EL + V+E T K E V P W KD L E D R+ L++ D K D G Y +++ S D V P+ E K IKK L D+ N + K VE G K + W+ E + + I ++ + L I +A G Y + ++ D V S +++ +E IS P F K L D + + L + PK + W K+G+ + + +V+ L + L I + + +D G Y N G ++A + V+ Sbjct: 3491 LEVREQETLDLKVTVIGTPVPNV----EWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVY-TCKATNEAGEA-KTTANMAVQEEIEAPLFVQGLKPY----EVEQGKPAELVVRVEGKPEPEVKW--FKDGVPI-AIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQA-TNKAGKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDT---VVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI-KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEA-------ENEYGSAWTE--GPIIVTLEGAPKIDGEAPD-FLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMD-EYRCEASNEFGDV-WSDVTLTVKEPAQVAPGFFKELSAIQVKETETA---KFECKVSGTKP-----DVKWFKDGTPLKE-DKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEV---SNDAGVANSKVPLTVVPSETLK------IKKGLTDV---NVTQGTKILLSVEVEGKPKTVKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKIS---------LPSFKKGLADQSVPKGTPLVLEVEIEGKPK-DVKWYKNGDEIK----DGKVEDLGNG-KYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVS 4299 HSP 8 Score: 70.4774 bits (171), Expect = 4.171e-11 Identity = 116/503 (23.06%), Postives = 200/503 (39.76%), Query Frame = 2 Query: 4919 WSKDDIDCSNN--GIFNSTKNKNCFNLTKLKAEITDSGVY------KFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDP----CVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFK-DEKVVSPILGELLSCTVEEVNTIEDEKIEL-SVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY----SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFE--NEEI--DAENMEFIQWSCDNYFALTIP-AAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 W KDD+ + F S ++ F +T ++TD+G Y ++ ++ + P + + C++ ++I EV W + + WL +D P D L I Q ++ +G+Y + NE E E+ V+ D+ V+P T+E V E E++ SV + P I +W + K L+E++ I C L ++DV GM S ++ +S D +KVR P P KPL+D ++ + V FEV+ SG + F +E+ E +E + D ++ ++IP + +KH G+ + N+ G S RL++ EQ E AP F K ++D + + E + +P P++ W +G +D VKI + L I A+ +G C N +G T+A ++V Sbjct: 581 WYKDDVQLHEDERHTFYSDED-GFFAMTIDPVQVTDTGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKE----CKEGDVI-------DFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPDD-TGVYTVKIQNEFGSIESKAELFVQADPDKNHVAP----EFQATIEYVECDEGEEVRFKSVITGDPNPEI---IWFINGKPLSESEKVKFISEDGICI-LTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP------------PTFNKPLEDKTVQEKSTVV---FEVDVSGWPEPTLTFTLCGKELKNGEEGVEIV--GHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV-------EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPG--VKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVV 1034 HSP 9 Score: 69.707 bits (169), Expect = 6.664e-11 Identity = 64/235 (27.23%), Postives = 105/235 (44.68%), Query Frame = 2 Query: 5792 EPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDG--------RLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFT--LIITEAEVEDSGRYCCLGTNFLGYDTT--EAVIIVTDSEPKESDSS-RIIVKPLCAPVLTAEYSKGADVI 6457 E + +K E +V+ S + +W+ + + + I S D L IP+ G Y + N G + G R S RS +++ + AP + L++I I K++ RL C+ DPKP I W KDGE + R++++ E P+ L++ A +D+G Y C+ N G T + +I D +P++ DSS R P LT +K D + Sbjct: 5714 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRS--ADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERV---FPYGRLQLI-ESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSV 5942 HSP 10 Score: 69.3218 bits (168), Expect = 7.878e-11 Identity = 225/1066 (21.11%), Postives = 428/1066 (40.15%), Query Frame = 2 Query: 3260 FFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKP--IDSNIETC--PGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLL-IDSVKLEDSGTY-ICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNG-EILEMKSDILSDIKNNGKIA-ELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKD--DIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFE-GMVDGKLLEL-VHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVL------DNPFIDLYIESPQVNEHSGLYKCIVTNEK-SETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFC---YNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF---IRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGY-DTTEAVIIV 6355 FF L I+ E + K D WF + L K + + + S + G ++ + + + ++ + V+ E + G D + + G + L++ + P T+K W+ +E + + + + E++ K+ I + E S YR+V + +S E + ++ K KI F+ L ++ + ++LE +I G K W+ N + +K+ + D + +L I Q D G+Y + A++ G++ S A + + KP + + T GE+ T V V+G K +KW K K + + + K N + S+ L I + ++ED+ Y + + S +T+ + D+ D ++ ++ +++ + T ++ V W+ NG EI K+ K+NG + L+I N Y+ ++ N G++ ++ L V+ I + + ++ E+ +G + L+V + +K + +W K+ +I S+ S + N L A D+ YK DG + TV+ L E ++ ED ++S P+ + +E + ++W +N ++P + DN ++ L I S V E +G YK V NE S +ITV+ K + P+ + ++ E E E SVE+ + + W K+ + E P I++ Y L++++ DA Y + + ESS + VK + K I K L+ + K + +F I+ EPE V+ W + I A I+ D + L IP+A K G+YT++V N+ G +SD + E+ E+ P + L++IEI ++ + P ++ W K+ + + KI + + L I A+++D Y + +N G D++ A+ +V Sbjct: 4020 FFKELSAIQVKETETAKFECKVSGTKPDV----KWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQ-----GTKILLSVEVEGKP-KTVK---WYKGTETVTSSQTTKIVQVTESEYKLEIESA--EMSDTGAYRVVLSTDSFSVESSATV--TVTKAAEKISLPSFKKGL------ADQSVPKGTPLVLEVEI-EGKPKDVK----WYKNGDEIKDGKVE-DLGNGKYRLTIPDFQEKDVGEYSVTA----ANEAGEIE-----SKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKW------YKNGKEIPDAKT--KDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQ--VKWYKNGKEIPNAKA------KDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSS-AALTVKLPGIAIVKGL-EDAEVPKGKKAVLQVETN-KKPKEIKWYKNGKEITPSDKAQPGSDGD-NKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVK-------LPAKEPKIIKGLEDQ--VVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV-LEIPS-SVVEDTGDYKVEVANEAGSANSSGKITVEPKI-TFLKPLKDQSIT---------EGENAEFSVETNTKPRIVK---WYKNGQ---EIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGAKMVFEVKIQGEPEDVR--------------WLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDA------KGEVDEK--------PEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPK--KYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4963 HSP 11 Score: 68.9366 bits (167), Expect = 1.101e-10 Identity = 157/732 (21.45%), Postives = 287/732 (39.21%), Query Frame = 2 Query: 4394 LLIDSVKLEDSGTYICQGF-------TNKELISE--CKITLNVVD------------NISDTLQCQVKFEKDKYS-IEINQDVTM----RALIECT---STHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNS-------STARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTV----QVNP-----IQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVL-----DNPFIDLYIESPQVNEHSGLYKCIVTNEKS-ETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDG-ETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKP 6406 L I + K ED G Y C+ TN +L + K+ +V D + DT + + +E+ + T+ +A+++C + W G+ +EM + + ++ K++G + L N ++ G Y C EN+ G++ T ++ D L V + +T G LE + +W K+ + ++ + + LT A++ D Y+ E + G + V TV QV P + +I + K C+ +S +KP + +W ++ P + + D+ L IE + ++ G Y+ V+N+ V +TV V S L + + +VN + KI LSVE K++ W K + + + + + Y L + +M+D G Y + ++ ESS + V TK K + +P KK L D + P+ EVE G K + W+ +EI +E + + + LTIP EK G+Y++ AN+ G + S ++++ + EI ++ + + E N ++ P + W K+G E D+K + + +++L I A+VED+ Y + +N G + A + V K +D + VKP Sbjct: 3744 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLT-LTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAV-VTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECK-----VSGTKPDV-------------KWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQ-GNYRIEVSNDAGVANSKVPLTV------VPSETL--KIKKGLTDVNVTQGTKILLSVEVEGKPKTVK---WYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTV----------TKAAEK-ISLPSFKKGLADQSV---PKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGKVEDL---GNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTT--------------VKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD------NGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTV-----KLADDGKDKVKP 4400 HSP 12 Score: 66.2402 bits (160), Expect = 6.995e-10 Identity = 85/362 (23.48%), Postives = 148/362 (40.88%), Query Frame = 2 Query: 5333 YKCIVTNE-KSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP--FCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFI-QWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDE---FPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVI-IVTDSEPKE 6376 YK I TN + T +IT K V +P+ + L T V E+ K+E+ V P W KD+K ++E D + P + L+++ TDAG Y+ K + ESS + E+ ++L+ P + L ++ ET V+ W + + + ++ I + +++TI A + GKY + N G +++ +++ + P F +KL +E+ KE+ L+ +++ P+P + W KD D+ V ++ + +F+L I +A D G Y C N G T A I+ DS P E Sbjct: 3165 YKAIATNSIGTATSTSKITTK-----VEAPVFEQGLKKT--SVKEKEEIKMEVKVGGSAP-----DVEWFKDDKPVSE-DGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEA--------------EVTQSLEKPTFVRELVTTEVKIN-ETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVV-----------KNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKD----DTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPE 3483 HSP 13 Score: 64.6994 bits (156), Expect = 2.516e-9 Identity = 172/819 (21.00%), Postives = 296/819 (36.14%), Query Frame = 2 Query: 4085 LEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKPID-----SNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSF-LLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHY-SVSWFFNGEILEM-KSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS--NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGM-VDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMP--FGDPC---VLDNPFIDLYIESPQVNEHSGLYKCIVTN-------------------------------EKSETEFVEITVKFK-DEKVVSPILGELL-SCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKI--------NESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILD-EFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSE 6367 + I +L DSG+Y C A + +V KNL P + S +E ES TL V V G + ++W + + D + + QK SF L I+ + D G Y C+ + E T N I D++ + F + +E+ + T+ + T +V WF + + + + S I + + +G L I+ G+Y C N+ G + T E I+ K E+ +G L V E + + + +W KD + + N + L D G Y + GK + + + T +E + I E + +++ +V I++ +ND P G VL++ I L I++ + E G Y+C N E + E V T K D +P ELL SCTV E K + ++ +V + W K+ K + + L +V DAG Y + E + + ++ PK + + P +P++ + ET E ++ W+ EE+ + I+ D LT+ A +Y + +N+ G V SD L++ E +AP F K+L I++ E + C+ + KP + W KDG L ++RV + L+I +++ +D G Y +N G ++ + V SE Sbjct: 3345 ITIKDARLEDSGKY-ACRATNPAGEAKTEANFAVV------KNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNV----HVIQKQTAVGSFSLTINDARQGDVGIYSCRA---RNEAGEALTTANF-GIIRDSIPPE--FTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHT-LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEK-QTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNAK-KEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTE-------KQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPK----------IDGEAPDFLQPVKPAVV-TVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVK----------EPAQVAPGFFKELSAIQVKETETAKFECK-VSGTKPDVKWFKDGTPLKE---DKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSE 4111 HSP 14 Score: 59.6918 bits (143), Expect = 7.452e-8 Identity = 94/384 (24.48%), Postives = 157/384 (40.89%), Query Frame = 2 Query: 5282 FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSP--ILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNET-DPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEI-DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVK 6403 F + I+ QV + +G Y C+ TNE + K EK +P + +L +E + I+ E VE P + VWL D++ L + D RL Q L +RD + D G+Y++KI ES ++ V+ P KN P+ + ++ + +E E V+F+ + + IWF + + ++E ++FI S D LTI G T Q +N +G DGRL + + P F K L+D + K + + P+P + +T G+ L + + D F ++ T + D G N G + A + V + E +ES S+ +K Sbjct: 603 FFAMTIDPVQVTD-TGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVID---FECEVEG-WPEPEL---VWLVDDQPLRPSHDFRLQYDGQ--TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPD----------KNHVAPEFQATIEYVEC-DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFI--SEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPP-----------APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIVAKAQNEHGTAESRARLTV-EQEEEESRSAPTFLK 950 HSP 15 Score: 58.5362 bits (140), Expect = 1.779e-7 Identity = 40/181 (22.10%), Postives = 79/181 (43.65%), Query Frame = 2 Query: 9044 CCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIY-FIIKNLEEDDFGEYCA-----LDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRV 9568 + +K E+K + + W F + K D +++ G++ ++K D G+Y A + ++ + + PT + L + ++E ++SV + P P V W ++ + + + VI + + G+YS+ I L D G+Y+ RA N G A+ + N V Sbjct: 3198 TSVKEKEEIKMEVKVGGSAPDVEW-FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAV 3377 HSP 16 Score: 56.9954 bits (136), Expect = 4.318e-7 Identity = 39/138 (28.26%), Postives = 64/138 (46.38%), Query Frame = 2 Query: 5957 CGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP 6370 GKYT V N G + L+++ E + AP F L+D + E + L C+++ +PKPK+ W D +T+ + + V+ ++ T IT +E+ G+Y C+ N G TEA + V P Sbjct: 2959 AGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK-----APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESIT--VESVEGVERVT--ITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAP 3087 HSP 17 Score: 55.4546 bits (132), Expect = 1.239e-6 Identity = 84/362 (23.20%), Postives = 144/362 (39.78%), Query Frame = 2 Query: 5327 GLYKCIVTNEKSETEF-----VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVE-SRVPTKSIDSAVWLKDEKLLNETDPRLTI-IMQPFCYNLILRDVKMTDAGMYSL-------KINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPN--FTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDS 6364 G+Y C+ NE + E VEI ++EK ++ +E+ + I LS + +P S+ VW KD L D R +I + L + D D G Y IN +S + VKV + ++K+ +E F K L D++ + ++ + V + W+ + + I+ S D +LT+ + G Y + N G ++ + + +E+ P F +L D+ + I L C++ P P + W+KDG L + R + +E + L I A V D G Y C+ TN G TT++ + + D Sbjct: 5346 GVYMCVAVNELGQAETQATYQVEILEHVEEEKRRE--YAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASV---VWYKDGLPLR-ADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTIN-TSCSVNVKVPKQEVKKEGEEPF-------FTKGLVDLWA-DRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL---IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDG 5689 HSP 18 Score: 55.4546 bits (132), Expect = 1.477e-6 Identity = 206/1044 (19.73%), Postives = 399/1044 (38.22%), Query Frame = 2 Query: 3362 WFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNV-LAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKP--IDSNIETC--PGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLL-IDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFE-----KDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIE---ITEGNELNLEV-VSEIEKDLQFQWSKDDIDCSNNGIFNSTK-NKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFI---------DLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPL 6409 W+ E + + V V+ES+ ++ + E+S +R+ FS E S V + K +S + + + G L L + + P K+ W+ N + I K E + K ++ IP+ ++ G +Y + E E K+ + P+I S L V + + E K+ G + K W+ N + + + K + + + LEI + Q+ D+ YK+ + +A L + K +KP + I T GE+ T V V+G K+ +KW K K + + K N + S+ L I + +L+D+ Y + N + + VK K E+ + +E + W+ NG+ + SD + +L I + + Y+ ++ ++DGN++ + L V+ + + K +E ++ G+ + LE+ S K +++ + ++ + K + N + L + + D+G YK +E+ + N I T E ++ + + +++ + SVE N K +++W +N G ++ FI L I++ V + + YK ++ N E E ++TVK + + G + + + KI+ E WL+D +++ + + Y LI+ + DAG Y+++ INES K E+ + P+I + L++I I PE F+VE S + + W+ ++EI + + + L I A Y + ++N G S L+++ + + LKD+++ + + L ++ PK I W K+G+ L + + E F+L I ++ D G Y + N G + +V+ V ++ E S + PL Sbjct: 4145 WYKGTETVTSSQTTKIVQVTESEYKLEI--ESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP----KDVKWYKNGDEIKDGKV---EDLGNGKYRLTIPDFQEKDVG--EYSVTAANEAGEIESKAKVN---VSAKPEIV-----SGL------VPTTVKQGETATFNVKV-KGPVKGVK----WYKNGKEIPDAKTKDNGDGSYS-LEIPNAQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQ-VKW------YKNGKEIPNAKA--KDNGDGSYSLEIPNAQLDDTADYKV-------------VVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEI-TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEP--KIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYK---------VEVANEAGSANSSGKI--TVEPKITFLKPLKDQSITEGENAEFSVET-NTKPRIVKWYKN----GQEIKPNSRFIIEQKTDTKYQLVIKN-AVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPED---------VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESG---------KAKSDAKGEVDEK---PEIVRGLENIEI---PEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLK------------IVDGLKDVDVEEPQPVELKVKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPL 5077 HSP 19 Score: 53.9138 bits (128), Expect = 4.532e-6 Identity = 138/651 (21.20%), Postives = 257/651 (39.48%), Query Frame = 2 Query: 4472 ECKITLNVVDNISDTLQCQVKFEKDKYSIEINQ-DVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNS-STARTELNVEN---IQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGM----VDGKLLEL-VHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGV-IQWLRNDMPFGDP---CVLDNPFIDLYIESPQVN-EHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVW-LKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRM-MCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP 6370 E K L V++ +T + + F +E+ + D +I S Y W+ NG +LE + ++ IKN + L I N +S + E N+ G+S S+A+ +N + I +D SVT I+ TE E + ++ W+ ++ + + K ++ + L A+I +G K D K +L V V+ +S LT + + + +PL ++E+ G + WL N P V+D+ ++ + E SG N E E ++TV ++K E + T+E E ++ S + V K + + W L ++KL+ + ++ + + ++ ++ M G ++ S + + K + K ++P+ + D ++ E E VKF VE W E + +++ D + I A + G+ + + N +G + D +L++ + AP F K L+D I E ++ ++ + PKPKI W KDG + S + V+ +E + L I + ++ED GR + G A + V P Sbjct: 1965 ETKTELKVLETPKETKKPE--FTDKLRDMEVTKGDTVQMDVIALHSPLYK--WYQNGNLLEDGKNGVT-IKNEENKSSLIIPNAQDSGKITVEA--SNEVGSSESSAQLTVNPPSTTPIVVDGPKSVT--IKETETAEFKATISGFPAPTVK--WTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLT-------------DKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNKKP------EFVQAPQNHETTLE-ESVKFS--AIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLK--------VDKKTEVPKFTTNMDDRQVK-EGEDVKFTANVEGYPEPSVAWTLNGEPV-SKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAV-----------KKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVE--EEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRP 2559
BLAST of Serine/threonine kinase vs. Ensembl Fly
Match: Unc-89 (gene:FBgn0053519 transcript:FBtr0343286) HSP 1 Score: 135.576 bits (340), Expect = 9.079e-31 Identity = 137/614 (22.31%), Postives = 256/614 (41.69%), Query Frame = 2 Query: 8705 EREITLSWSPP-RISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTT------------EKAMMLQEKHCLAVPMFCCLSQKAELKF-------------TKLM----EYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEED-DFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDA------------HPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--------SEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLA-EYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLC--GFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH-----------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +R + LSW+P ++P I + +++ P E W +T ++ DI +L+P +Y+ R+ FG+ PS + R+ + P T E + + + P L+Q + T+LM Y K+T+ F++ ++ + ++ FI K L+ D + E A +E + Q L ++ P L + +N I ++ P PEV W ++WK I S R I+ + Y L I I+ DGG YSI A N G + ++ HP +S Q+ D+Y +L +G+ +E+S+ + K GR +E + + +H+N++ +DA D+ + LI E G L + + + ++ E + I Q + + ++HE V H+ + ++++++ +I+K+ G S + + + + + G+ F +PE++ E + F+ DMW++G++T++ L GH L EG + ++ IS+ FI + LL ER+ +L H WF Sbjct: 1939 DRGLLLSWNPSVPLTPRYPITYQIEMMDLP-------EGDWRTLRTGVRSCACDIRNLEPFRDYRFRVRVENKFGVSDPSPYTQTYRQKLVPDPPKTYTYLPPGTDFRPETSPYFPKDFDIERPPHDGLAQAPQFLLREQDISYGVKDHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEARQRVRLEIAEHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKISS-YDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQYIYKTYGRHPYVRSKQLRY---QDKYDIGDELGRGTQGITYHAVERSSGDNYAAKIM------YGRPELRPFMLNELEMMNTFNHKNLIRPYDAYDT-DRSVTLIMELAAGGELVRDNLLRRDYYTERDIAHYIRQTLWGLEHMHEMGVGHMGLTIKDLLISVVGGDIIKVSDFGLSRKINRHNLSTLDY-GMPE-FVSPEVVNKEGVNFSHDMWTVGLITYVLLGGHNPFLGIDDRETLTKIREGRWDFKDEIWTHISDDGRDFISRLLLYSPEERMDVKTALKHPWF 2532 HSP 2 Score: 116.316 bits (290), Expect = 5.858e-25 Identity = 103/426 (24.18%), Postives = 192/426 (45.07%), Query Frame = 2 Query: 10808 LGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSR-NKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSI--ATSVFQNKIRNIHSLK-----QALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMED-----ICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 +G + W+KN +LT+ RIK+ V + G A DVG+++ +AR +T R+V+ +P P+ + + E+LL+W DD + ++ + + W T+ ++D+ YLL +L Y R+ ++N+ G+S I + S IH K Q L N ++ + H D H + + + + + + YS +S+ + G +K + +V + ++ D + FD +++ P LF ++ I E + G ++L+ +R YSE V T++ QLL +Q+LH H NI+P ++++ + +S +KL+ + + V + + +T F+ PE + +SDIWSLG L++LLL+ P Sbjct: 2770 VGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEISANSGTEILLRWK---QPRDDGHSTVLCYSLQYKLSNCDAWTTVADNIDHEFYLLHDLQPNTNYQFRLASKNRIGWSEMGIPVSASTVGGDAPKIHITKAMKHLQQLTENGHQVVPEEERVH-TDYH--CEREPPNWVTDSSVSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVPIAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMA--SVRSIQVKLVDFGSAKKVNKLGMK--VTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP 3185 HSP 3 Score: 109.383 bits (272), Expect = 7.566e-23 Identity = 73/264 (27.65%), Postives = 119/264 (45.08%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDA---IAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSN------------DAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFI 10354 V+D+Y + ++A+G +S I+KST + K E+ + +EF + + H I +F A + +P + + EKLQG + Y + + E V ++ QL+ A+ YLH CHL+I+P+N++M + +KL F +A G + + F PE++ EPI SD+WS+G LT+L L G F G Y N ++ A FI +R + D L H W + Sbjct: 2985 VSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVP--IAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMASVRSIQVKLVDFGSAKKVNKLGMKVTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP--FRGADEYETKQNISFVRYRFENLFKEVTPEATRFIMLLFKRHPTKRPYTEDCLEHRWLM 3244 HSP 4 Score: 95.9005 bits (237), Expect = 1.131e-18 Identity = 180/814 (22.11%), Postives = 305/814 (37.47%), Query Frame = 2 Query: 4073 NLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAP----IKKNLKPID----SNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQD----KILQEKRITQKFNNNLSF--LLIDSVKLEDSGTYICQGFTNKELISECKITLNVVD--NISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNS-VTKNIEITEGNELNLEVVSEIEKDLQ--------FQWSKD----DIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVLDNPFIDLYIESPQVN------EHSGLYKCIVTNEKSET-EFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INE-----SSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIA----PLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSE 6367 N +L+I +C +D+G Y I AS+ V+ V AP K N +P + E V + G K +K+ E ++ + +I+++K + L F L+I V+ D+GTY C+ TNK + C+ V+ N L Q+ +K + W NGE + + + L Q+ GIY C+ + GN S + EL+V+ I LN K + E E N + +LQ QW D +D + ++ +++ +L + D+GVY E + + G+ ++ V+ P ++K I + I S + + + +EV + Q +Q N D+ + + I +E V +G Y TN+ S+T E+ TVK K P++ + E I EK + + R+ W DE + TD + T+ Y L + DAG Y++K NE SS +L+K P+ K L++I + V+ V+ A W+ + EID + +F N F L + G YT ++ ND G ++ ++C + P + LK++E+ ++ L + +P+ KI W KDG + + + N+ L + A ED+G Y TNF+G T+ + V SE Sbjct: 164 NSYRLDIKNCSETDAGTYTI--RAQSASETTTVSAQLAVGQAPGHDETKTNTEPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDK-------DYLGFYELVIADVQKTDAGTYSCKA-TNKHGEANCEAIATTVEDKNPFGALSGQILPAGEKPVFQ---------------------WKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCS-AELSVQG-AIQTLNREPEKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMY---EDEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPP----------KIKKITD---ITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSK------PVIVKNF-----ESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCAPEFTHK-----------------LKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYG------------------KLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVLTSE 882 HSP 5 Score: 92.0485 bits (227), Expect = 1.307e-17 Identity = 110/405 (27.16%), Postives = 176/405 (43.46%), Query Frame = 2 Query: 5150 DNEIILSDSKPLIISVEVLNWKQGVIQWLRND---MPFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCY-NLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF-IRNEPETVKFEFEVEESGAKKAIWFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTT 6337 DN + + +PL++ V +QWL++ P + NP + L I S Q N+ SG YK I++N E + V K E++ L + S TV + E ++L E++V W KD LL + P + I P LI+ + DAG+Y I +I + + + K++K +F LQD I P VK + +V + K WF EI DA ++ ++ + DN +L I G Y + N G S +L + +++ E E AP F L+D+ + + L+ + +P P+++W+KDG TL N R+ + + + L I AE DSG Y CL N LG D++ Sbjct: 1319 DNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPND-SGAYKLIISNPHGE-KVALCAVAVKPEEMQPKFLKPITSQTV-----VVGEPLKL--EAQVTGFPAPEVKWYKDGMLLRPS-PEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFV--------AELQDASSIEGFP--VKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVE-NPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKAD--ETATEE---APQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTP---NERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSS 1694 HSP 6 Score: 68.1662 bits (165), Expect = 2.542e-10 Identity = 99/386 (25.65%), Postives = 160/386 (41.45%), Query Frame = 2 Query: 3929 SLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTS--NLAQLEIAHCQLSDSGQYK-ICFNPLEASKCGKVTGLFLVSIAPIK---KNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFN--NNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIE---INQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLN-------SVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVY 5032 +L++ + E ++LE + + + QW + + VK K T+ L +LEI CQ +DSG YK I NP G+ L V++ P + K LKPI S GE + L V GF ++KW K +L+ N N L+ID+ + D+G Y C NK E + +V S + V +D SIE + D+ + + + WF NG ++ + ++ ++N + L I+ G+YE + +N +G S+ ++ +L V + S +++ EG EL L + WSKD + + N T + LT AE DSG Y Sbjct: 1321 ALDVLQGEPLVLECCVDGSPLPTV----QWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNP-----HGEKVALCAVAVKPEEMQPKFLKPITSQTVVV-GEPLKLEAQVTGFPAPEVKW------YKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCL-IANKGGEIEGVSKVEIVPKESKPVF--VAELQDASSIEGFPVKMDIKV-----VGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEG-STASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNY 1681 HSP 7 Score: 64.6994 bits (156), Expect = 2.567e-9 Identity = 201/958 (20.98%), Postives = 369/958 (38.52%), Query Frame = 2 Query: 3629 LNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFT---SNLAQLEIAHCQLSDSGQYKI-CFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVK--------FEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVT---KNIEITEGNELNLEVVSEIEK--DLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPF---------GDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFV-EITVKFKDEKVVSPILGELLSCTVEE-----------VNTIED---EKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKI----------NESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPET----VKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEF--PNFTLIITEAEVEDSGRYCCLGTNFLG 6325 L A + P+ K G + E V F +E + + +V +V E +G+ S + ++G++ QT E EK L++E + +I + + L+ K + P + +D V ++ + F L I + D+G Y I N L + + + LV AP K +K I ++I GE++ + ++VEGF + ++ D+ + ++ + + + + +KL +G Y + N + S+ C VK FE + E ++V M I+ ++W+ + +++ +D + ++G LKI G Y N+ G S+T+ T+L I C T KNI + EG+ N+E+V ++ +W D I+ F + N F L + G Y + M D GKL + TV P ++K ++ E+ + K + VEV + + I+W ++ D ++N ++ L + E +G Y+ TN ET ++ V + + + + L T EE V+ + E + L E A+W D K + D I + Y L ++ + + DAG Y + + E S+ + + R KPI Q + K++K+ + K + + +P +K V E+ K + ++ DAEN +Q++C L I A K G+Y ++V N G + + G + ++ + EIS L D + L + I + +PKPK+ WT+ E L C + +++ + + L+ + G+Y TN G Sbjct: 323 LPAGEKPVFQWKRNGEEFDPEERFKVLFGEDE----DSLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSVQGAI--QTLNREPEK--PTLVIEHREANASIGGSAILELQCK-------GFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDTVDAGVYTIEAINELGQDE----SSINLVVKAPPK--IKKI-TDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKA-------------TNDLSQTSEYWSCTVKSKPVIVKNFESEYIHGE-KENVQMTVRIDAYP-EAKLTWYHDETEIKI-TDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHG-SATSSTQL-----LIKCAPEFTHKLKNITVAEGDS-NVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNCKP----------KVKRGLKNVEV--QEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLAR---TEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPIT-PDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYR-KPILTQGPGL-KDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVK----LKVDKKDAENG-LVQYTC----TLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEIS---------------GLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENL---CNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEG 1190 HSP 8 Score: 63.1586 bits (152), Expect = 7.889e-9 Identity = 122/575 (21.22%), Postives = 230/575 (40.00%), Query Frame = 2 Query: 4703 LKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFE-GMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDM---PFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFV-EITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP-FCYNLILRDVKMTDAGMYSLKIN--ESSVDILVK--VRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDN-YFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDS 6385 L I++ E+ G Y C+ N+ G + A +L + ++ + + +++ +G L LE + QW KD + + I ST L + DSG YK G+ + L V+ +Q LK I ++ +PL + +V + ++W ++ M P + +++P I L I++ Q + +G+YKC++ N+ E E V ++ + K+ K V + EL ++ ++IE +++ + +V W + + + I+ P +LI+ D+G+Y + E S K V PK T+E PQ L+D+ +E + + + + IW + + E + +CD + LTI A G YT +AN +G S + P+FT+K+ D + + N ++ + P P + W + + + + I ++ + LI+ E D G Y C+ +N G D T+ + + + K S S Sbjct: 1275 LDIKSFRENDVGAYTCVATNEIG-VTKAPFKLAMLSLAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKF------LKPITSQTVVV---GEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLD-AGVYKCLIANKGGEIEGVSKVEIVPKESKPV--FVAEL-----QDASSIEGFPVKMDI--KVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEA------PQFVSALRDVNA-DEGQELVLSAPFISNPMPEVIW--SKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLG-----------EDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPK---SEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDITQGRLDIVNEIKKHSRS 1806 HSP 9 Score: 57.3806 bits (137), Expect = 3.849e-7 Identity = 59/237 (24.89%), Postives = 104/237 (43.88%), Query Frame = 2 Query: 5711 RKQTKEIFKNLKIPQIKKPLQDIFIRNEP-ETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCD--NYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKD-GETLDSKCLNRRVKIL---DEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAV-IIVTDSEPKESDSSRII 6397 R Q +++ P + K L+ + + EP ET FE + ++ W +N+ ++ + I + N + L I E G YTI+ + +L++ E + P F LKD E++ R +++ DPKP++ + KD E L++ N R++I+ D + L+I + + D+G Y C TN G EA+ V D P + S +I+ Sbjct: 96 RLQEDRPLRSVDKPVVVKMLKSVQV--EPGETAHFEIQFKDQPGL-VTWLKDNKPLEDRLADRITQTAAPMNSYRLDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNT---EPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILET---NDRIQIIRDKDYLGFYELVIADVQKTDAGTYSCKATNKHGEANCEAIATTVEDKNPFGALSGQIL 323
BLAST of Serine/threonine kinase vs. Ensembl Fly
Match: Unc-89 (gene:FBgn0053519 transcript:FBtr0113464) HSP 1 Score: 135.191 bits (339), Expect = 1.343e-30 Identity = 136/610 (22.30%), Postives = 257/610 (42.13%), Query Frame = 2 Query: 8705 EREITLSWSPP-RISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTT------------EKAMMLQEKHCLAVPMFCCLSQKAELKF-------------TKLM----EYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEED-DFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDA------------HPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFF----EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLA-EYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLC--GFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH-----------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +R + LSW+P ++P I + +++ P E W +T ++ DI +L+P +Y+ R+ FG+ PS + R+ + P T E + + + P L+Q + T+LM Y K+T+ F++ ++ + ++ FI K L+ D + E A +E + Q L ++ P L + +N I ++ P PEV W ++WK I S R I+ + Y L I I+ DGG YSI A N G + ++ HP +S Q+ D+Y +L +G+ +E+S+ + K E+ + +E + + +H+N++ +DA D+ + LI E G L + + + ++ E + I Q + + ++HE V H+ + ++++++ +I+K+ G S + + + + + G+ F +PE++ E + F+ DMW++G++T++ L GH L EG + ++ IS+ FI + LL ER+ +L H WF Sbjct: 2847 DRGLLLSWNPSVPLTPRYPITYQIEMMDLP-------EGDWRTLRTGVRSCACDIRNLEPFRDYRFRVRVENKFGVSDPSPYTQTYRQKLVPDPPKTYTYLPPGTDFRPETSPYFPKDFDIERPPHDGLAQAPQFLLREQDISYGVKDHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEARQRVRLEIAEHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKIS-SYDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQYIYKTYGRHPYVRSKQLRY---QDKYDIGDELGRGTQGITYHAVERSSGDNYAAKIMYGRPELRPFML--NELEMMNTFNHKNLIRPYDAYDT-DRSVTLIMELAAGGELVRDNLLRRDYYTERDIAHYIRQTLWGLEHMHEMGVGHMGLTIKDLLISVVGGDIIKVSDFGLSRKINRHNLSTLDY-GMPE-FVSPEVVNKEGVNFSHDMWTVGLITYVLLGGHNPFLGIDDRETLTKIREGRWDFKDEIWTHISDDGRDFISRLLLYSPEERMDVKTALKHPWF 3440 HSP 2 Score: 116.316 bits (290), Expect = 6.852e-25 Identity = 103/426 (24.18%), Postives = 192/426 (45.07%), Query Frame = 2 Query: 10808 LGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSR-NKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSI--ATSVFQNKIRNIHSLK-----QALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMED-----ICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 +G + W+KN +LT+ RIK+ V + G A DVG+++ +AR +T R+V+ +P P+ + + E+LL+W DD + ++ + + W T+ ++D+ YLL +L Y R+ ++N+ G+S I + S IH K Q L N ++ + H D H + + + + + + YS +S+ + G +K + +V + ++ D + FD +++ P LF ++ I E + G ++L+ +R YSE V T++ QLL +Q+LH H NI+P ++++ + +S +KL+ + + V + + +T F+ PE + +SDIWSLG L++LLL+ P Sbjct: 3678 VGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEISANSGTEILLRWK---QPRDDGHSTVLCYSLQYKLSNCDAWTTVADNIDHEFYLLHDLQPNTNYQFRLASKNRIGWSEMGIPVSASTVGGDAPKIHITKAMKHLQQLTENGHQVVPEEERVH-TDYH--CEREPPNWVTDSSVSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVPIAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMA--SVRSIQVKLVDFGSAKKVNKLGMK--VTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP 4093 HSP 3 Score: 109.768 bits (273), Expect = 6.365e-23 Identity = 73/264 (27.65%), Postives = 119/264 (45.08%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDA---IAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSN------------DAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFI 10354 V+D+Y + ++A+G +S I+KST + K E+ + +EF + + H I +F A + +P + + EKLQG + Y + + E V ++ QL+ A+ YLH CHL+I+P+N++M + +KL F +A G + + F PE++ EPI SD+WS+G LT+L L G F G Y N ++ A FI +R + D L H W + Sbjct: 3893 VSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVP--IAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMASVRSIQVKLVDFGSAKKVNKLGMKVTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP--FRGADEYETKQNISFVRYRFENLFKEVTPEATRFIMLLFKRHPTKRPYTEDCLEHRWLM 4152 HSP 4 Score: 95.9005 bits (237), Expect = 1.020e-18 Identity = 180/814 (22.11%), Postives = 305/814 (37.47%), Query Frame = 2 Query: 4073 NLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAP----IKKNLKPID----SNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQD----KILQEKRITQKFNNNLSF--LLIDSVKLEDSGTYICQGFTNKELISECKITLNVVD--NISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNS-VTKNIEITEGNELNLEVVSEIEKDLQ--------FQWSKD----DIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVLDNPFIDLYIESPQVN------EHSGLYKCIVTNEKSET-EFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INE-----SSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIA----PLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSE 6367 N +L+I +C +D+G Y I AS+ V+ V AP K N +P + E V + G K +K+ E ++ + +I+++K + L F L+I V+ D+GTY C+ TNK + C+ V+ N L Q+ +K + W NGE + + + L Q+ GIY C+ + GN S + EL+V+ I LN K + E E N + +LQ QW D +D + ++ +++ +L + D+GVY E + + G+ ++ V+ P ++K I + I S + + + +EV + Q +Q N D+ + + I +E V +G Y TN+ S+T E+ TVK K P++ + E I EK + + R+ W DE + TD + T+ Y L + DAG Y++K NE SS +L+K P+ K L++I + V+ V+ A W+ + EID + +F N F L + G YT ++ ND G ++ ++C + P + LK++E+ ++ L + +P+ KI W KDG + + + N+ L + A ED+G Y TNF+G T+ + V SE Sbjct: 1072 NSYRLDIKNCSETDAGTYTI--RAQSASETTTVSAQLAVGQAPGHDETKTNTEPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDK-------DYLGFYELVIADVQKTDAGTYSCKA-TNKHGEANCEAIATTVEDKNPFGALSGQILPAGEKPVFQ---------------------WKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCS-AELSVQGA-IQTLNREPEKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMY---EDEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPP----------KIKKITD---ITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSK------PVIVKNF-----ESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCAPEFTHK-----------------LKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYG------------------KLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVLTSE 1790 HSP 5 Score: 92.4337 bits (228), Expect = 1.129e-17 Identity = 110/405 (27.16%), Postives = 176/405 (43.46%), Query Frame = 2 Query: 5150 DNEIILSDSKPLIISVEVLNWKQGVIQWLRND---MPFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCY-NLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF-IRNEPETVKFEFEVEESGAKKAIWFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTT 6337 DN + + +PL++ V +QWL++ P + NP + L I S Q N+ SG YK I++N E + V K E++ L + S TV + E ++L E++V W KD LL + P + I P LI+ + DAG+Y I +I + + + K++K +F LQD I P VK + +V + K WF EI DA ++ ++ + DN +L I G Y + N G S +L + +++ E E AP F L+D+ + + L+ + +P P+++W+KDG TL N R+ + + + L I AE DSG Y CL N LG D++ Sbjct: 2227 DNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPND-SGAYKLIISNPHGE-KVALCAVAVKPEEMQPKFLKPITSQTV-----VVGEPLKL--EAQVTGFPAPEVKWYKDGMLLRPS-PEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFV--------AELQDASSIEGFP--VKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVE-NPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKAD--ETATEE---APQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTP---NERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSS 2602 HSP 6 Score: 68.9366 bits (167), Expect = 1.556e-10 Identity = 99/386 (25.65%), Postives = 160/386 (41.45%), Query Frame = 2 Query: 3929 SLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTS--NLAQLEIAHCQLSDSGQYK-ICFNPLEASKCGKVTGLFLVSIAPIK---KNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFN--NNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIE---INQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLN-------SVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVY 5032 +L++ + E ++LE + + + QW + + VK K T+ L +LEI CQ +DSG YK I NP G+ L V++ P + K LKPI S GE + L V GF ++KW K +L+ N N L+ID+ + D+G Y C NK E + +V S + V +D SIE + D+ + + + WF NG ++ + ++ ++N + L I+ G+YE + +N +G S+ ++ +L V + S +++ EG EL L + WSKD + + N T + LT AE DSG Y Sbjct: 2229 ALDVLQGEPLVLECCVDGSPLPTV----QWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNP-----HGEKVALCAVAVKPEEMQPKFLKPITSQTVVV-GEPLKLEAQVTGFPAPEVKW------YKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCL-IANKGGEIEGVSKVEIVPKESKPVF--VAELQDASSIEGFPVKMDIKV-----VGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEG-STASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNY 2589 HSP 7 Score: 64.3142 bits (155), Expect = 3.420e-9 Identity = 201/958 (20.98%), Postives = 369/958 (38.52%), Query Frame = 2 Query: 3629 LNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFT---SNLAQLEIAHCQLSDSGQYKI-CFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVK--------FEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVT---KNIEITEGNELNLEVVSEIEK--DLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPF---------GDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFV-EITVKFKDEKVVSPILGELLSCTVEE-----------VNTIED---EKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKI----------NESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPET----VKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEF--PNFTLIITEAEVEDSGRYCCLGTNFLG 6325 L A + P+ K G + E V F +E + + +V +V E +G+ S + ++G++ QT E EK L++E + +I + + L+ K + P + +D V ++ + F L I + D+G Y I N L + + + LV AP K +K I ++I GE++ + ++VEGF + ++ D+ + ++ + + + + +KL +G Y + N + S+ C VK FE + E ++V M I+ ++W+ + +++ +D + ++G LKI G Y N+ G S+T+ T+L I C T KNI + EG+ N+E+V ++ +W D I+ F + N F L + G Y + M D GKL + TV P ++K ++ E+ + K + VEV + + I+W ++ D ++N ++ L + E +G Y+ TN ET ++ V + + + + L T EE V+ + E + L E A+W D K + D I + Y L ++ + + DAG Y + + E S+ + + R KPI Q + K++K+ + K + + +P +K V E+ K + ++ DAEN +Q++C L I A K G+Y ++V N G + + G + ++ + EIS L D + L + I + +PKPK+ WT+ E L C + +++ + + L+ + G+Y TN G Sbjct: 1231 LPAGEKPVFQWKRNGEEFDPEERFKVLFGEDE----DSLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSVQGAI--QTLNREPEK--PTLVIEHREANASIGGSAILELQCK-------GFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDTVDAGVYTIEAINELGQDE----SSINLVVKAPPK--IKKI-TDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKA-------------TNDLSQTSEYWSCTVKSKPVIVKNFESEYIHGE-KENVQMTVRIDAYP-EAKLTWYHDETEIKI-TDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHG-SATSSTQL-----LIKCAPEFTHKLKNITVAEGDS-NVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNCKP----------KVKRGLKNVEV--QEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLAR---TEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPIT-PDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYR-KPILTQGPGL-KDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVK----LKVDKKDAENG-LVQYTC----TLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEIS---------------GLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENL---CNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEG 2098 HSP 8 Score: 63.1586 bits (152), Expect = 8.238e-9 Identity = 122/575 (21.22%), Postives = 230/575 (40.00%), Query Frame = 2 Query: 4703 LKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFE-GMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDM---PFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFV-EITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP-FCYNLILRDVKMTDAGMYSLKIN--ESSVDILVK--VRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDN-YFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDS 6385 L I++ E+ G Y C+ N+ G + A +L + ++ + + +++ +G L LE + QW KD + + I ST L + DSG YK G+ + L V+ +Q LK I ++ +PL + +V + ++W ++ M P + +++P I L I++ Q + +G+YKC++ N+ E E V ++ + K+ K V + EL ++ ++IE +++ + +V W + + + I+ P +LI+ D+G+Y + E S K V PK T+E PQ L+D+ +E + + + + IW + + E + +CD + LTI A G YT +AN +G S + P+FT+K+ D + + N ++ + P P + W + + + + I ++ + LI+ E D G Y C+ +N G D T+ + + + K S S Sbjct: 2183 LDIKSFRENDVGAYTCVATNEIG-VTKAPFKLAMLSLAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKF------LKPITSQTVVV---GEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLD-AGVYKCLIANKGGEIEGVSKVEIVPKESKPV--FVAEL-----QDASSIEGFPVKMDI--KVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEA------PQFVSALRDVNA-DEGQELVLSAPFISNPMPEVIW--SKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLG-----------EDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPK---SEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDITQGRLDIVNEIKKHSRS 2714 HSP 9 Score: 57.7658 bits (138), Expect = 3.628e-7 Identity = 59/237 (24.89%), Postives = 104/237 (43.88%), Query Frame = 2 Query: 5711 RKQTKEIFKNLKIPQIKKPLQDIFIRNEP-ETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCD--NYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKD-GETLDSKCLNRRVKIL---DEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAV-IIVTDSEPKESDSSRII 6397 R Q +++ P + K L+ + + EP ET FE + ++ W +N+ ++ + I + N + L I E G YTI+ + +L++ E + P F LKD E++ R +++ DPKP++ + KD E L++ N R++I+ D + L+I + + D+G Y C TN G EA+ V D P + S +I+ Sbjct: 1004 RLQEDRPLRSVDKPVVVKMLKSVQV--EPGETAHFEIQFKDQPGL-VTWLKDNKPLEDRLADRITQTAAPMNSYRLDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNT---EPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILET---NDRIQIIRDKDYLGFYELVIADVQKTDAGTYSCKATNKHGEANCEAIATTVEDKNPFGALSGQIL 1231
BLAST of Serine/threonine kinase vs. Ensembl Fly
Match: Unc-89 (gene:FBgn0053519 transcript:FBtr0343284) HSP 1 Score: 135.191 bits (339), Expect = 1.376e-30 Identity = 136/610 (22.30%), Postives = 257/610 (42.13%), Query Frame = 2 Query: 8705 EREITLSWSPP-RISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTT------------EKAMMLQEKHCLAVPMFCCLSQKAELKF-------------TKLM----EYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEED-DFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDA------------HPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFF----EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLA-EYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLC--GFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH-----------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +R + LSW+P ++P I + +++ P E W +T ++ DI +L+P +Y+ R+ FG+ PS + R+ + P T E + + + P L+Q + T+LM Y K+T+ F++ ++ + ++ FI K L+ D + E A +E + Q L ++ P L + +N I ++ P PEV W ++WK I S R I+ + Y L I I+ DGG YSI A N G + ++ HP +S Q+ D+Y +L +G+ +E+S+ + K E+ + +E + + +H+N++ +DA D+ + LI E G L + + + ++ E + I Q + + ++HE V H+ + ++++++ +I+K+ G S + + + + + G+ F +PE++ E + F+ DMW++G++T++ L GH L EG + ++ IS+ FI + LL ER+ +L H WF Sbjct: 2822 DRGLLLSWNPSVPLTPRYPITYQIEMMDLP-------EGDWRTLRTGVRSCACDIRNLEPFRDYRFRVRVENKFGVSDPSPYTQTYRQKLVPDPPKTYTYLPPGTDFRPETSPYFPKDFDIERPPHDGLAQAPQFLLREQDISYGVKDHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEARQRVRLEIAEHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKISS-YDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQYIYKTYGRHPYVRSKQLRY---QDKYDIGDELGRGTQGITYHAVERSSGDNYAAKIMYGRPELRPFML--NELEMMNTFNHKNLIRPYDAYDT-DRSVTLIMELAAGGELVRDNLLRRDYYTERDIAHYIRQTLWGLEHMHEMGVGHMGLTIKDLLISVVGGDIIKVSDFGLSRKINRHNLSTLDY-GMPE-FVSPEVVNKEGVNFSHDMWTVGLITYVLLGGHNPFLGIDDRETLTKIREGRWDFKDEIWTHISDDGRDFISRLLLYSPEERMDVKTALKHPWF 3415 HSP 2 Score: 116.316 bits (290), Expect = 6.403e-25 Identity = 103/426 (24.18%), Postives = 192/426 (45.07%), Query Frame = 2 Query: 10808 LGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSR-NKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSI--ATSVFQNKIRNIHSLK-----QALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMED-----ICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 +G + W+KN +LT+ RIK+ V + G A DVG+++ +AR +T R+V+ +P P+ + + E+LL+W DD + ++ + + W T+ ++D+ YLL +L Y R+ ++N+ G+S I + S IH K Q L N ++ + H D H + + + + + + YS +S+ + G +K + +V + ++ D + FD +++ P LF ++ I E + G ++L+ +R YSE V T++ QLL +Q+LH H NI+P ++++ + +S +KL+ + + V + + +T F+ PE + +SDIWSLG L++LLL+ P Sbjct: 3653 VGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEISANSGTEILLRWK---QPRDDGHSTVLCYSLQYKLSNCDAWTTVADNIDHEFYLLHDLQPNTNYQFRLASKNRIGWSEMGIPVSASTVGGDAPKIHITKAMKHLQQLTENGHQVVPEEERVH-TDYH--CEREPPNWVTDSSVSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVPIAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMA--SVRSIQVKLVDFGSAKKVNKLGMK--VTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP 4068 HSP 3 Score: 109.768 bits (273), Expect = 6.413e-23 Identity = 73/264 (27.65%), Postives = 119/264 (45.08%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDA---IAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSN------------DAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFI 10354 V+D+Y + ++A+G +S I+KST + K E+ + +EF + + H I +F A + +P + + EKLQG + Y + + E V ++ QL+ A+ YLH CHL+I+P+N++M + +KL F +A G + + F PE++ EPI SD+WS+G LT+L L G F G Y N ++ A FI +R + D L H W + Sbjct: 3868 VSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVP--IAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMASVRSIQVKLVDFGSAKKVNKLGMKVTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP--FRGADEYETKQNISFVRYRFENLFKEVTPEATRFIMLLFKRHPTKRPYTEDCLEHRWLM 4127 HSP 4 Score: 93.2041 bits (230), Expect = 6.544e-18 Identity = 178/810 (21.98%), Postives = 303/810 (37.41%), Query Frame = 2 Query: 4073 NLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAP----IKKNLKPID----SNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQD----KILQEKRITQKFNNNLSF--LLIDSVKLEDSGTYICQGFTNKELISECKITLNVVD--NISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNS-VTKNIEITEGNELNLEVVSEIEKDLQ--------FQWSKD----DIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVLDNPFIDLYIESPQVN------EHSGLYKCIVTNEKSET-EFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INE-----SSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIA----PLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 N +L+I +C +D+G Y I AS+ V+ V AP K N +P + E V + G K +K+ E ++ + +I+++K + L F L+I V+ D+GTY C+ TNK + C+ V+ N L Q+ +K + W NGE + + + L Q+ GIY C+ + GN S + EL+V+ I LN K + E E N + +LQ QW D +D + ++ +++ +L + D+GVY E + + G+ ++ V+ P ++K I + I S + + + +EV + Q +Q N D+ + + I +E V +G Y TN+ S+T E+ TVK K P++ + E I EK + + R+ W DE + TD + T+ Y L + DAG Y++K NE SS +L+K P+ K L++I + V+ V+ A W+ + EID + +F N F L + G YT ++ ND G ++ ++C + P + LK++E+ ++ L + +P+ KI W KDG + + + N+ L + A ED+G Y TNF+G T+ + V Sbjct: 1072 NSYRLDIKNCSETDAGTYTI--RAQSASETTTVSAQLAVGQAPGHDETKTNTEPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDK-------DYLGFYELVIADVQKTDAGTYSCKA-TNKHGEANCEAIATTVEDKNPFGALSGQILPAGEKPVFQ---------------------WKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCS-AELSVQGA-IQTLNREPEKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMY---EDEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPP----------KIKKITD---ITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSK------PVIVKNF-----ESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCAPEFTHK-----------------LKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYG------------------KLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAV 1786 HSP 5 Score: 92.8189 bits (229), Expect = 9.225e-18 Identity = 110/405 (27.16%), Postives = 176/405 (43.46%), Query Frame = 2 Query: 5150 DNEIILSDSKPLIISVEVLNWKQGVIQWLRND---MPFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCY-NLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF-IRNEPETVKFEFEVEESGAKKAIWFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTT 6337 DN + + +PL++ V +QWL++ P + NP + L I S Q N+ SG YK I++N E + V K E++ L + S TV + E ++L E++V W KD LL + P + I P LI+ + DAG+Y I +I + + + K++K +F LQD I P VK + +V + K WF EI DA ++ ++ + DN +L I G Y + N G S +L + +++ E E AP F L+D+ + + L+ + +P P+++W+KDG TL N R+ + + + L I AE DSG Y CL N LG D++ Sbjct: 2202 DNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPND-SGAYKLIISNPHGE-KVALCAVAVKPEEMQPKFLKPITSQTV-----VVGEPLKL--EAQVTGFPAPEVKWYKDGMLLRPS-PEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFV--------AELQDASSIEGFP--VKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVE-NPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKAD--ETATEE---APQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTP---NERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSS 2577 HSP 6 Score: 69.3218 bits (168), Expect = 1.103e-10 Identity = 99/386 (25.65%), Postives = 160/386 (41.45%), Query Frame = 2 Query: 3929 SLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTS--NLAQLEIAHCQLSDSGQYK-ICFNPLEASKCGKVTGLFLVSIAPIK---KNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFN--NNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIE---INQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLN-------SVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVY 5032 +L++ + E ++LE + + + QW + + VK K T+ L +LEI CQ +DSG YK I NP G+ L V++ P + K LKPI S GE + L V GF ++KW K +L+ N N L+ID+ + D+G Y C NK E + +V S + V +D SIE + D+ + + + WF NG ++ + ++ ++N + L I+ G+YE + +N +G S+ ++ +L V + S +++ EG EL L + WSKD + + N T + LT AE DSG Y Sbjct: 2204 ALDVLQGEPLVLECCVDGSPLPTV----QWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNP-----HGEKVALCAVAVKPEEMQPKFLKPITSQTVVV-GEPLKLEAQVTGFPAPEVKW------YKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCL-IANKGGEIEGVSKVEIVPKESKPVF--VAELQDASSIEGFPVKMDIKV-----VGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEG-STASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNY 2564 HSP 7 Score: 66.6254 bits (161), Expect = 7.830e-10 Identity = 199/944 (21.08%), Postives = 368/944 (38.98%), Query Frame = 2 Query: 3629 LNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFT---SNLAQLEIAHCQLSDSGQYKI-CFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVK--------FEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVT---KNIEITEGNELNLEVVSEIEK--DLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPF---------GDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSV-ESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKI----------NESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPET----VKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEF--PNFTLIITEAEVEDSGRYCCLGTNFLG 6325 L A + P+ K G + E V F +E + + +V +V E +G+ S + ++G++ QT E EK L++E + +I + + L+ K + P + +D V ++ + F L I + D+G Y I N L + + + LV AP K +K I ++I GE++ + ++VEGF + ++ D+ + ++ + + + + +KL +G Y + N + S+ C VK FE + E ++V M I+ ++W+ + +++ +D + ++G LKI G Y N+ G S+T+ T+L I C T KNI + EG+ N+E+V ++ +W D I+ F + N F L + G Y + M D GKL + TV P ++K ++ E+ + K + VEV + + I+W ++ D ++N ++ L + E +G Y+ TN ET KV + E++ V + ++ E ++ V + +P A+W D K + D I + Y L ++ + + DAG Y + + E S+ + + R KPI Q + K++K+ + K + + +P +K V E+ K + ++ DAEN +Q++C L I A K G+Y ++V N G + + G + ++ + EIS L D + L + I + +PKPK+ WT+ E L C + +++ + + L+ + G+Y TN G Sbjct: 1231 LPAGEKPVFQWKRNGEEFDPEERFKVLFGEDE----DSLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSVQGAI--QTLNREPEK--PTLVIEHREANASIGGSAILELQCK-------GFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDTVDAGVYTIEAINELGQDE----SSINLVVKAPPK--IKKI-TDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKA-------------TNDLSQTSEYWSCTVKSKPVIVKNFESEYIHGE-KENVQMTVRIDAYP-EAKLTWYHDETEIKI-TDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHG-SATSSTQL-----LIKCAPEFTHKLKNITVAEGDS-NVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNCKP----------KVKRGLKNVEV--QEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLAR---TEDAGTYEMKATNFIGETT--------STCKVAVLTVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPE---AIWYHDGKPIT-PDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYR-KPILTQGPGL-KDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVK----LKVDKKDAENG-LVQYTC----TLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEIS---------------GLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENL---CNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEG 2073 HSP 8 Score: 63.5438 bits (153), Expect = 6.965e-9 Identity = 122/575 (21.22%), Postives = 230/575 (40.00%), Query Frame = 2 Query: 4703 LKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFE-GMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDM---PFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFV-EITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP-FCYNLILRDVKMTDAGMYSLKIN--ESSVDILVK--VRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDN-YFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDS 6385 L I++ E+ G Y C+ N+ G + A +L + ++ + + +++ +G L LE + QW KD + + I ST L + DSG YK G+ + L V+ +Q LK I ++ +PL + +V + ++W ++ M P + +++P I L I++ Q + +G+YKC++ N+ E E V ++ + K+ K V + EL ++ ++IE +++ + +V W + + + I+ P +LI+ D+G+Y + E S K V PK T+E PQ L+D+ +E + + + + IW + + E + +CD + LTI A G YT +AN +G S + P+FT+K+ D + + N ++ + P P + W + + + + I ++ + LI+ E D G Y C+ +N G D T+ + + + K S S Sbjct: 2158 LDIKSFRENDVGAYTCVATNEIG-VTKAPFKLAMLSLAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKF------LKPITSQTVVV---GEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLD-AGVYKCLIANKGGEIEGVSKVEIVPKESKPV--FVAEL-----QDASSIEGFPVKMDI--KVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEA------PQFVSALRDVNA-DEGQELVLSAPFISNPMPEVIW--SKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLG-----------EDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPK---SEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDITQGRLDIVNEIKKHSRS 2689 HSP 9 Score: 57.7658 bits (138), Expect = 3.507e-7 Identity = 59/237 (24.89%), Postives = 104/237 (43.88%), Query Frame = 2 Query: 5711 RKQTKEIFKNLKIPQIKKPLQDIFIRNEP-ETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCD--NYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKD-GETLDSKCLNRRVKIL---DEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAV-IIVTDSEPKESDSSRII 6397 R Q +++ P + K L+ + + EP ET FE + ++ W +N+ ++ + I + N + L I E G YTI+ + +L++ E + P F LKD E++ R +++ DPKP++ + KD E L++ N R++I+ D + L+I + + D+G Y C TN G EA+ V D P + S +I+ Sbjct: 1004 RLQEDRPLRSVDKPVVVKMLKSVQV--EPGETAHFEIQFKDQPGL-VTWLKDNKPLEDRLADRITQTAAPMNSYRLDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNT---EPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILET---NDRIQIIRDKDYLGFYELVIADVQKTDAGTYSCKATNKHGEANCEAIATTVEDKNPFGALSGQIL 1231
BLAST of Serine/threonine kinase vs. Ensembl Fly
Match: Unc-89 (gene:FBgn0053519 transcript:FBtr0343285) HSP 1 Score: 135.191 bits (339), Expect = 1.385e-30 Identity = 136/610 (22.30%), Postives = 257/610 (42.13%), Query Frame = 2 Query: 8705 EREITLSWSPP-RISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTT------------EKAMMLQEKHCLAVPMFCCLSQKAELKF-------------TKLM----EYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEED-DFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDA------------HPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFF----EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLA-EYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLC--GFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH-----------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +R + LSW+P ++P I + +++ P E W +T ++ DI +L+P +Y+ R+ FG+ PS + R+ + P T E + + + P L+Q + T+LM Y K+T+ F++ ++ + ++ FI K L+ D + E A +E + Q L ++ P L + +N I ++ P PEV W ++WK I S R I+ + Y L I I+ DGG YSI A N G + ++ HP +S Q+ D+Y +L +G+ +E+S+ + K E+ + +E + + +H+N++ +DA D+ + LI E G L + + + ++ E + I Q + + ++HE V H+ + ++++++ +I+K+ G S + + + + + G+ F +PE++ E + F+ DMW++G++T++ L GH L EG + ++ IS+ FI + LL ER+ +L H WF Sbjct: 2594 DRGLLLSWNPSVPLTPRYPITYQIEMMDLP-------EGDWRTLRTGVRSCACDIRNLEPFRDYRFRVRVENKFGVSDPSPYTQTYRQKLVPDPPKTYTYLPPGTDFRPETSPYFPKDFDIERPPHDGLAQAPQFLLREQDISYGVKDHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEARQRVRLEIAEHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKIS-SYDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQYIYKTYGRHPYVRSKQLRY---QDKYDIGDELGRGTQGITYHAVERSSGDNYAAKIMYGRPELRPFML--NELEMMNTFNHKNLIRPYDAYDT-DRSVTLIMELAAGGELVRDNLLRRDYYTERDIAHYIRQTLWGLEHMHEMGVGHMGLTIKDLLISVVGGDIIKVSDFGLSRKINRHNLSTLDY-GMPE-FVSPEVVNKEGVNFSHDMWTVGLITYVLLGGHNPFLGIDDRETLTKIREGRWDFKDEIWTHISDDGRDFISRLLLYSPEERMDVKTALKHPWF 3187 HSP 2 Score: 116.316 bits (290), Expect = 6.351e-25 Identity = 103/426 (24.18%), Postives = 192/426 (45.07%), Query Frame = 2 Query: 10808 LGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSR-NKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSI--ATSVFQNKIRNIHSLK-----QALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMED-----ICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 +G + W+KN +LT+ RIK+ V + G A DVG+++ +AR +T R+V+ +P P+ + + E+LL+W DD + ++ + + W T+ ++D+ YLL +L Y R+ ++N+ G+S I + S IH K Q L N ++ + H D H + + + + + + YS +S+ + G +K + +V + ++ D + FD +++ P LF ++ I E + G ++L+ +R YSE V T++ QLL +Q+LH H NI+P ++++ + +S +KL+ + + V + + +T F+ PE + +SDIWSLG L++LLL+ P Sbjct: 3425 VGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEISANSGTEILLRWK---QPRDDGHSTVLCYSLQYKLSNCDAWTTVADNIDHEFYLLHDLQPNTNYQFRLASKNRIGWSEMGIPVSASTVGGDAPKIHITKAMKHLQQLTENGHQVVPEEERVH-TDYH--CEREPPNWVTDSSVSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVPIAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMA--SVRSIQVKLVDFGSAKKVNKLGMK--VTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP 3840 HSP 3 Score: 109.768 bits (273), Expect = 6.155e-23 Identity = 73/264 (27.65%), Postives = 119/264 (45.08%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDA---IAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSN------------DAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFI 10354 V+D+Y + ++A+G +S I+KST + K E+ + +EF + + H I +F A + +P + + EKLQG + Y + + E V ++ QL+ A+ YLH CHL+I+P+N++M + +KL F +A G + + F PE++ EPI SD+WS+G LT+L L G F G Y N ++ A FI +R + D L H W + Sbjct: 3640 VSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVP--IAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMASVRSIQVKLVDFGSAKKVNKLGMKVTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP--FRGADEYETKQNISFVRYRFENLFKEVTPEATRFIMLLFKRHPTKRPYTEDCLEHRWLM 3899 HSP 4 Score: 96.6709 bits (239), Expect = 5.827e-19 Identity = 180/814 (22.11%), Postives = 305/814 (37.47%), Query Frame = 2 Query: 4073 NLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAP----IKKNLKPID----SNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQD----KILQEKRITQKFNNNLSF--LLIDSVKLEDSGTYICQGFTNKELISECKITLNVVD--NISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNS-VTKNIEITEGNELNLEVVSEIEKDLQ--------FQWSKD----DIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVLDNPFIDLYIESPQVN------EHSGLYKCIVTNEKSET-EFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INE-----SSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIA----PLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSE 6367 N +L+I +C +D+G Y I AS+ V+ V AP K N +P + E V + G K +K+ E ++ + +I+++K + L F L+I V+ D+GTY C+ TNK + C+ V+ N L Q+ +K + W NGE + + + L Q+ GIY C+ + GN S + EL+V+ I LN K + E E N + +LQ QW D +D + ++ +++ +L + D+GVY E + + G+ ++ V+ P ++K I + I S + + + +EV + Q +Q N D+ + + I +E V +G Y TN+ S+T E+ TVK K P++ + E I EK + + R+ W DE + TD + T+ Y L + DAG Y++K NE SS +L+K P+ K L++I + V+ V+ A W+ + EID + +F N F L + G YT ++ ND G ++ ++C + P + LK++E+ ++ L + +P+ KI W KDG + + + N+ L + A ED+G Y TNF+G T+ + V SE Sbjct: 819 NSYRLDIKNCSETDAGTYTI--RAQSASETTTVSAQLAVGQAPGHDETKTNTEPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDK-------DYLGFYELVIADVQKTDAGTYSCKA-TNKHGEANCEAIATTVEDKNPFGALSGQILPAGEKPVFQ---------------------WKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCS-AELSVQGA-IQTLNREPEKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMY---EDEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPP----------KIKKITD---ITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSK------PVIVKNF-----ESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCAPEFTHK-----------------LKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYG------------------KLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVLTSE 1537 HSP 5 Score: 93.2041 bits (230), Expect = 6.781e-18 Identity = 110/405 (27.16%), Postives = 176/405 (43.46%), Query Frame = 2 Query: 5150 DNEIILSDSKPLIISVEVLNWKQGVIQWLRND---MPFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCY-NLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF-IRNEPETVKFEFEVEESGAKKAIWFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTT 6337 DN + + +PL++ V +QWL++ P + NP + L I S Q N+ SG YK I++N E + V K E++ L + S TV + E ++L E++V W KD LL + P + I P LI+ + DAG+Y I +I + + + K++K +F LQD I P VK + +V + K WF EI DA ++ ++ + DN +L I G Y + N G S +L + +++ E E AP F L+D+ + + L+ + +P P+++W+KDG TL N R+ + + + L I AE DSG Y CL N LG D++ Sbjct: 1974 DNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPND-SGAYKLIISNPHGE-KVALCAVAVKPEEMQPKFLKPITSQTV-----VVGEPLKL--EAQVTGFPAPEVKWYKDGMLLRPS-PEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFV--------AELQDASSIEGFP--VKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVE-NPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKAD--ETATEE---APQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTP---NERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSS 2349 HSP 6 Score: 69.707 bits (169), Expect = 8.617e-11 Identity = 99/386 (25.65%), Postives = 160/386 (41.45%), Query Frame = 2 Query: 3929 SLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTS--NLAQLEIAHCQLSDSGQYK-ICFNPLEASKCGKVTGLFLVSIAPIK---KNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFN--NNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIE---INQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLN-------SVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVY 5032 +L++ + E ++LE + + + QW + + VK K T+ L +LEI CQ +DSG YK I NP G+ L V++ P + K LKPI S GE + L V GF ++KW K +L+ N N L+ID+ + D+G Y C NK E + +V S + V +D SIE + D+ + + + WF NG ++ + ++ ++N + L I+ G+YE + +N +G S+ ++ +L V + S +++ EG EL L + WSKD + + N T + LT AE DSG Y Sbjct: 1976 ALDVLQGEPLVLECCVDGSPLPTV----QWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNP-----HGEKVALCAVAVKPEEMQPKFLKPITSQTVVV-GEPLKLEAQVTGFPAPEVKW------YKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCL-IANKGGEIEGVSKVEIVPKESKPVF--VAELQDASSIEGFPVKMDIKV-----VGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEG-STASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNY 2336 HSP 7 Score: 65.0846 bits (157), Expect = 1.911e-9 Identity = 201/958 (20.98%), Postives = 369/958 (38.52%), Query Frame = 2 Query: 3629 LNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFT---SNLAQLEIAHCQLSDSGQYKI-CFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVK--------FEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVT---KNIEITEGNELNLEVVSEIEK--DLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPF---------GDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFV-EITVKFKDEKVVSPILGELLSCTVEE-----------VNTIED---EKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKI----------NESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPET----VKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEF--PNFTLIITEAEVEDSGRYCCLGTNFLG 6325 L A + P+ K G + E V F +E + + +V +V E +G+ S + ++G++ QT E EK L++E + +I + + L+ K + P + +D V ++ + F L I + D+G Y I N L + + + LV AP K +K I ++I GE++ + ++VEGF + ++ D+ + ++ + + + + +KL +G Y + N + S+ C VK FE + E ++V M I+ ++W+ + +++ +D + ++G LKI G Y N+ G S+T+ T+L I C T KNI + EG+ N+E+V ++ +W D I+ F + N F L + G Y + M D GKL + TV P ++K ++ E+ + K + VEV + + I+W ++ D ++N ++ L + E +G Y+ TN ET ++ V + + + + L T EE V+ + E + L E A+W D K + D I + Y L ++ + + DAG Y + + E S+ + + R KPI Q + K++K+ + K + + +P +K V E+ K + ++ DAEN +Q++C L I A K G+Y ++V N G + + G + ++ + EIS L D + L + I + +PKPK+ WT+ E L C + +++ + + L+ + G+Y TN G Sbjct: 978 LPAGEKPVFQWKRNGEEFDPEERFKVLFGEDE----DSLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSVQGAI--QTLNREPEK--PTLVIEHREANASIGGSAILELQCK-------GFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDTVDAGVYTIEAINELGQDE----SSINLVVKAPPK--IKKI-TDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKA-------------TNDLSQTSEYWSCTVKSKPVIVKNFESEYIHGE-KENVQMTVRIDAYP-EAKLTWYHDETEIKI-TDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHG-SATSSTQL-----LIKCAPEFTHKLKNITVAEGDS-NVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNCKP----------KVKRGLKNVEV--QEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLAR---TEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPIT-PDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYR-KPILTQGPGL-KDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVK----LKVDKKDAENG-LVQYTC----TLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEIS---------------GLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENL---CNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEG 1845 HSP 8 Score: 63.929 bits (154), Expect = 5.047e-9 Identity = 122/575 (21.22%), Postives = 230/575 (40.00%), Query Frame = 2 Query: 4703 LKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFE-GMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDM---PFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFV-EITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP-FCYNLILRDVKMTDAGMYSLKIN--ESSVDILVK--VRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDN-YFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDS 6385 L I++ E+ G Y C+ N+ G + A +L + ++ + + +++ +G L LE + QW KD + + I ST L + DSG YK G+ + L V+ +Q LK I ++ +PL + +V + ++W ++ M P + +++P I L I++ Q + +G+YKC++ N+ E E V ++ + K+ K V + EL ++ ++IE +++ + +V W + + + I+ P +LI+ D+G+Y + E S K V PK T+E PQ L+D+ +E + + + + IW + + E + +CD + LTI A G YT +AN +G S + P+FT+K+ D + + N ++ + P P + W + + + + I ++ + LI+ E D G Y C+ +N G D T+ + + + K S S Sbjct: 1930 LDIKSFRENDVGAYTCVATNEIG-VTKAPFKLAMLSLAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKF------LKPITSQTVVV---GEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLD-AGVYKCLIANKGGEIEGVSKVEIVPKESKPV--FVAEL-----QDASSIEGFPVKMDI--KVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEA------PQFVSALRDVNA-DEGQELVLSAPFISNPMPEVIW--SKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLG-----------EDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPK---SEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDITQGRLDIVNEIKKHSRS 2461 HSP 9 Score: 57.7658 bits (138), Expect = 3.082e-7 Identity = 59/237 (24.89%), Postives = 104/237 (43.88%), Query Frame = 2 Query: 5711 RKQTKEIFKNLKIPQIKKPLQDIFIRNEP-ETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCD--NYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKD-GETLDSKCLNRRVKIL---DEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAV-IIVTDSEPKESDSSRII 6397 R Q +++ P + K L+ + + EP ET FE + ++ W +N+ ++ + I + N + L I E G YTI+ + +L++ E + P F LKD E++ R +++ DPKP++ + KD E L++ N R++I+ D + L+I + + D+G Y C TN G EA+ V D P + S +I+ Sbjct: 751 RLQEDRPLRSVDKPVVVKMLKSVQV--EPGETAHFEIQFKDQPGL-VTWLKDNKPLEDRLADRITQTAAPMNSYRLDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNT---EPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILET---NDRIQIIRDKDYLGFYELVIADVQKTDAGTYSCKATNKHGEANCEAIATTVEDKNPFGALSGQIL 978
BLAST of Serine/threonine kinase vs. Ensembl Fly
Match: Unc-89 (gene:FBgn0053519 transcript:FBtr0343283) HSP 1 Score: 135.191 bits (339), Expect = 1.435e-30 Identity = 136/610 (22.30%), Postives = 257/610 (42.13%), Query Frame = 2 Query: 8705 EREITLSWSPP-RISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTT------------EKAMMLQEKHCLAVPMFCCLSQKAELKF-------------TKLM----EYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEED-DFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDA------------HPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFF----EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLA-EYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLC--GFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH-----------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +R + LSW+P ++P I + +++ P E W +T ++ DI +L+P +Y+ R+ FG+ PS + R+ + P T E + + + P L+Q + T+LM Y K+T+ F++ ++ + ++ FI K L+ D + E A +E + Q L ++ P L + +N I ++ P PEV W ++WK I S R I+ + Y L I I+ DGG YSI A N G + ++ HP +S Q+ D+Y +L +G+ +E+S+ + K E+ + +E + + +H+N++ +DA D+ + LI E G L + + + ++ E + I Q + + ++HE V H+ + ++++++ +I+K+ G S + + + + + G+ F +PE++ E + F+ DMW++G++T++ L GH L EG + ++ IS+ FI + LL ER+ +L H WF Sbjct: 2823 DRGLLLSWNPSVPLTPRYPITYQIEMMDLP-------EGDWRTLRTGVRSCACDIRNLEPFRDYRFRVRVENKFGVSDPSPYTQTYRQKLVPDPPKTYTYLPPGTDFRPETSPYFPKDFDIERPPHDGLAQAPQFLLREQDISYGVKDHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEARQRVRLEIAEHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKISS-YDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQYIYKTYGRHPYVRSKQLRY---QDKYDIGDELGRGTQGITYHAVERSSGDNYAAKIMYGRPELRPFML--NELEMMNTFNHKNLIRPYDAYDT-DRSVTLIMELAAGGELVRDNLLRRDYYTERDIAHYIRQTLWGLEHMHEMGVGHMGLTIKDLLISVVGGDIIKVSDFGLSRKINRHNLSTLDY-GMPE-FVSPEVVNKEGVNFSHDMWTVGLITYVLLGGHNPFLGIDDRETLTKIREGRWDFKDEIWTHISDDGRDFISRLLLYSPEERMDVKTALKHPWF 3416 HSP 2 Score: 116.316 bits (290), Expect = 6.733e-25 Identity = 103/426 (24.18%), Postives = 192/426 (45.07%), Query Frame = 2 Query: 10808 LGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSR-NKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSI--ATSVFQNKIRNIHSLK-----QALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMED-----ICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 +G + W+KN +LT+ RIK+ V + G A DVG+++ +AR +T R+V+ +P P+ + + E+LL+W DD + ++ + + W T+ ++D+ YLL +L Y R+ ++N+ G+S I + S IH K Q L N ++ + H D H + + + + + + YS +S+ + G +K + +V + ++ D + FD +++ P LF ++ I E + G ++L+ +R YSE V T++ QLL +Q+LH H NI+P ++++ + +S +KL+ + + V + + +T F+ PE + +SDIWSLG L++LLL+ P Sbjct: 3654 VGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEISANSGTEILLRWK---QPRDDGHSTVLCYSLQYKLSNCDAWTTVADNIDHEFYLLHDLQPNTNYQFRLASKNRIGWSEMGIPVSASTVGGDAPKIHITKAMKHLQQLTENGHQVVPEEERVH-TDYH--CEREPPNWVTDSSVSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVPIAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMA--SVRSIQVKLVDFGSAKKVNKLGMK--VTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP 4069 HSP 3 Score: 109.768 bits (273), Expect = 6.577e-23 Identity = 73/264 (27.65%), Postives = 119/264 (45.08%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDA---IAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSN------------DAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFI 10354 V+D+Y + ++A+G +S I+KST + K E+ + +EF + + H I +F A + +P + + EKLQG + Y + + E V ++ QL+ A+ YLH CHL+I+P+N++M + +KL F +A G + + F PE++ EPI SD+WS+G LT+L L G F G Y N ++ A FI +R + D L H W + Sbjct: 3869 VSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVP--IAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMASVRSIQVKLVDFGSAKKVNKLGMKVTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP--FRGADEYETKQNISFVRYRFENLFKEVTPEATRFIMLLFKRHPTKRPYTEDCLEHRWLM 4128 HSP 4 Score: 93.2041 bits (230), Expect = 6.328e-18 Identity = 178/810 (21.98%), Postives = 303/810 (37.41%), Query Frame = 2 Query: 4073 NLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAP----IKKNLKPID----SNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQD----KILQEKRITQKFNNNLSF--LLIDSVKLEDSGTYICQGFTNKELISECKITLNVVD--NISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNS-VTKNIEITEGNELNLEVVSEIEKDLQ--------FQWSKD----DIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVLDNPFIDLYIESPQVN------EHSGLYKCIVTNEKSET-EFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INE-----SSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIA----PLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 N +L+I +C +D+G Y I AS+ V+ V AP K N +P + E V + G K +K+ E ++ + +I+++K + L F L+I V+ D+GTY C+ TNK + C+ V+ N L Q+ +K + W NGE + + + L Q+ GIY C+ + GN S + EL+V+ I LN K + E E N + +LQ QW D +D + ++ +++ +L + D+GVY E + + G+ ++ V+ P ++K I + I S + + + +EV + Q +Q N D+ + + I +E V +G Y TN+ S+T E+ TVK K P++ + E I EK + + R+ W DE + TD + T+ Y L + DAG Y++K NE SS +L+K P+ K L++I + V+ V+ A W+ + EID + +F N F L + G YT ++ ND G ++ ++C + P + LK++E+ ++ L + +P+ KI W KDG + + + N+ L + A ED+G Y TNF+G T+ + V Sbjct: 1073 NSYRLDIKNCSETDAGTYTI--RAQSASETTTVSAQLAVGQAPGHDETKTNTEPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDK-------DYLGFYELVIADVQKTDAGTYSCKA-TNKHGEANCEAIATTVEDKNPFGALSGQILPAGEKPVFQ---------------------WKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCS-AELSVQGA-IQTLNREPEKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMY---EDEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPP----------KIKKITD---ITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSK------PVIVKNF-----ESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCAPEFTHK-----------------LKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYG------------------KLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAV 1787 HSP 5 Score: 92.8189 bits (229), Expect = 8.996e-18 Identity = 110/405 (27.16%), Postives = 176/405 (43.46%), Query Frame = 2 Query: 5150 DNEIILSDSKPLIISVEVLNWKQGVIQWLRND---MPFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCY-NLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF-IRNEPETVKFEFEVEESGAKKAIWFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTT 6337 DN + + +PL++ V +QWL++ P + NP + L I S Q N+ SG YK I++N E + V K E++ L + S TV + E ++L E++V W KD LL + P + I P LI+ + DAG+Y I +I + + + K++K +F LQD I P VK + +V + K WF EI DA ++ ++ + DN +L I G Y + N G S +L + +++ E E AP F L+D+ + + L+ + +P P+++W+KDG TL N R+ + + + L I AE DSG Y CL N LG D++ Sbjct: 2203 DNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPND-SGAYKLIISNPHGE-KVALCAVAVKPEEMQPKFLKPITSQTV-----VVGEPLKL--EAQVTGFPAPEVKWYKDGMLLRPS-PEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFV--------AELQDASSIEGFP--VKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVE-NPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKAD--ETATEE---APQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTP---NERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSS 2578 HSP 6 Score: 69.3218 bits (168), Expect = 1.094e-10 Identity = 99/386 (25.65%), Postives = 160/386 (41.45%), Query Frame = 2 Query: 3929 SLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTS--NLAQLEIAHCQLSDSGQYK-ICFNPLEASKCGKVTGLFLVSIAPIK---KNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFN--NNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIE---INQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLN-------SVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVY 5032 +L++ + E ++LE + + + QW + + VK K T+ L +LEI CQ +DSG YK I NP G+ L V++ P + K LKPI S GE + L V GF ++KW K +L+ N N L+ID+ + D+G Y C NK E + +V S + V +D SIE + D+ + + + WF NG ++ + ++ ++N + L I+ G+YE + +N +G S+ ++ +L V + S +++ EG EL L + WSKD + + N T + LT AE DSG Y Sbjct: 2205 ALDVLQGEPLVLECCVDGSPLPTV----QWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNP-----HGEKVALCAVAVKPEEMQPKFLKPITSQTVVV-GEPLKLEAQVTGFPAPEVKW------YKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCL-IANKGGEIEGVSKVEIVPKESKPVF--VAELQDASSIEGFPVKMDIKV-----VGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEG-STASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNY 2565 HSP 7 Score: 66.6254 bits (161), Expect = 7.830e-10 Identity = 199/944 (21.08%), Postives = 368/944 (38.98%), Query Frame = 2 Query: 3629 LNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFT---SNLAQLEIAHCQLSDSGQYKI-CFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVK--------FEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVT---KNIEITEGNELNLEVVSEIEK--DLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPF---------GDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSV-ESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKI----------NESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPET----VKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEF--PNFTLIITEAEVEDSGRYCCLGTNFLG 6325 L A + P+ K G + E V F +E + + +V +V E +G+ S + ++G++ QT E EK L++E + +I + + L+ K + P + +D V ++ + F L I + D+G Y I N L + + + LV AP K +K I ++I GE++ + ++VEGF + ++ D+ + ++ + + + + +KL +G Y + N + S+ C VK FE + E ++V M I+ ++W+ + +++ +D + ++G LKI G Y N+ G S+T+ T+L I C T KNI + EG+ N+E+V ++ +W D I+ F + N F L + G Y + M D GKL + TV P ++K ++ E+ + K + VEV + + I+W ++ D ++N ++ L + E +G Y+ TN ET KV + E++ V + ++ E ++ V + +P A+W D K + D I + Y L ++ + + DAG Y + + E S+ + + R KPI Q + K++K+ + K + + +P +K V E+ K + ++ DAEN +Q++C L I A K G+Y ++V N G + + G + ++ + EIS L D + L + I + +PKPK+ WT+ E L C + +++ + + L+ + G+Y TN G Sbjct: 1232 LPAGEKPVFQWKRNGEEFDPEERFKVLFGEDE----DSLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSVQGAI--QTLNREPEK--PTLVIEHREANASIGGSAILELQCK-------GFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDTVDAGVYTIEAINELGQDE----SSINLVVKAPPK--IKKI-TDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKA-------------TNDLSQTSEYWSCTVKSKPVIVKNFESEYIHGE-KENVQMTVRIDAYP-EAKLTWYHDETEIKI-TDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHG-SATSSTQL-----LIKCAPEFTHKLKNITVAEGDS-NVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNCKP----------KVKRGLKNVEV--QEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLAR---TEDAGTYEMKATNFIGETT--------STCKVAVLTVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPE---AIWYHDGKPIT-PDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYR-KPILTQGPGL-KDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVK----LKVDKKDAENG-LVQYTC----TLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEIS---------------GLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENL---CNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEG 2074 HSP 8 Score: 63.5438 bits (153), Expect = 6.736e-9 Identity = 122/575 (21.22%), Postives = 230/575 (40.00%), Query Frame = 2 Query: 4703 LKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFE-GMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDM---PFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFV-EITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP-FCYNLILRDVKMTDAGMYSLKIN--ESSVDILVK--VRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDN-YFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDS 6385 L I++ E+ G Y C+ N+ G + A +L + ++ + + +++ +G L LE + QW KD + + I ST L + DSG YK G+ + L V+ +Q LK I ++ +PL + +V + ++W ++ M P + +++P I L I++ Q + +G+YKC++ N+ E E V ++ + K+ K V + EL ++ ++IE +++ + +V W + + + I+ P +LI+ D+G+Y + E S K V PK T+E PQ L+D+ +E + + + + IW + + E + +CD + LTI A G YT +AN +G S + P+FT+K+ D + + N ++ + P P + W + + + + I ++ + LI+ E D G Y C+ +N G D T+ + + + K S S Sbjct: 2159 LDIKSFRENDVGAYTCVATNEIG-VTKAPFKLAMLSLAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKF------LKPITSQTVVV---GEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLD-AGVYKCLIANKGGEIEGVSKVEIVPKESKPV--FVAEL-----QDASSIEGFPVKMDI--KVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEA------PQFVSALRDVNA-DEGQELVLSAPFISNPMPEVIW--SKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLG-----------EDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPK---SEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDITQGRLDIVNEIKKHSRS 2690 HSP 9 Score: 57.7658 bits (138), Expect = 3.449e-7 Identity = 59/237 (24.89%), Postives = 104/237 (43.88%), Query Frame = 2 Query: 5711 RKQTKEIFKNLKIPQIKKPLQDIFIRNEP-ETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCD--NYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKD-GETLDSKCLNRRVKIL---DEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAV-IIVTDSEPKESDSSRII 6397 R Q +++ P + K L+ + + EP ET FE + ++ W +N+ ++ + I + N + L I E G YTI+ + +L++ E + P F LKD E++ R +++ DPKP++ + KD E L++ N R++I+ D + L+I + + D+G Y C TN G EA+ V D P + S +I+ Sbjct: 1005 RLQEDRPLRSVDKPVVVKMLKSVQV--EPGETAHFEIQFKDQPGL-VTWLKDNKPLEDRLADRITQTAAPMNSYRLDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNT---EPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILET---NDRIQIIRDKDYLGFYELVIADVQKTDAGTYSCKATNKHGEANCEAIATTVEDKNPFGALSGQIL 1232
BLAST of Serine/threonine kinase vs. Ensembl Zebrafish
Match: spegb (striated muscle enriched protein kinase b [Source:ZFIN;Acc:ZDB-GENE-081104-517]) HSP 1 Score: 131.339 bits (329), Expect = 2.839e-29 Identity = 129/576 (22.40%), Postives = 252/576 (43.75%), Query Frame = 2 Query: 8708 REITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEG------WSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGEYCALDEVQDPIQSFILI--KSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRV--------DAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFF--EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAV---PKE----DFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKV-NFEGDQLYNEDSN-DAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 + ITLSW P+ +D P + Y+ ++ W++ + +K+ I++L + Y R++ +T KPS + ++ D P ++A ++ +K P + +K L T + + +TW + +++ + + ++ D G+ + + S +L + APT + + + + E +V ++ +P P+++W + + SS+ T + +D E SL++ D G Y+ A+N G K L V D ++ S+ + + D Y K++ +G++S + VI+K+ ++E+ KF E + ++ H I+ DA + V+I +L L + +T+ S ES++R + QL++ ++YLH+ + HLDIKP+NI+M ++ +++C F NAV P E +G T F APE++ P+ +D+ G+ F + V N + E+S + + A F+ K LL+ R +++ L H WF Sbjct: 1027 KTITLSWKKPK---------RLDPSIDPSSLMYAIQQQALGSIQWTIIASCLKQTTYTISNLSKGVRYAFRVLSITSKAFSKPSPATEPMQLLDR--GPYVQEAPVIIDK-----PDIVYMVEKQPLSITVTLNHVNASVTWKRGGVTLSNRPGLFELSMPDDDQHTLKLCKVKSSDVGQLTCIANNKYGSDSCVLTLEMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVYDDNE---CSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTVHTTKQYKDDPMEDEASILRKMRRLTDYYDVHKEIGRGAFSYVKRVIQKAGKLEYAAKFISARAKRKASALRELNILSHLDHERILYFHDAFE--KKNAVIIITELCHEELLDRLTKKSTILESEIRSSVRQLLEGINYLHQLDILHLDIKPDNILMADHSSDQIRICDFGNAVKFMPDEAQYCKYG-------TPEFVAPEIVNQTPVSKATDICLTGVSPFAGENDRSSVLNIRNYNVAFEESMFTDLCHEAKGFVIK-LLVADRLRPDANECLRHPWF 1573 HSP 2 Score: 105.145 bits (261), Expect = 1.926e-21 Identity = 77/264 (29.17%), Postives = 124/264 (46.97%), Query Frame = 2 Query: 9626 YYTMKKLAKGSYSRCQIVIEKSTQIEFIGKF--FEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSP-----FSAPELLKGEPIQFNSDMWSIGILTFLCLHGHL---------------KVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 Y M + A+G + + E +T ++ K +E + E+ ++++ H I+ + +A P +YLVLI E G L + + E V I Q++Q + YLH R+ HLDIKPENII+T Y ++K+ F +A + F + P + +PE+LKG+ + +D+WSIGILT++ L G L F+ +LY +S SA +FI+K L R T D ++ W Sbjct: 2753 YTFMDEKARGRFGVIRECRENATGNLYMAKIVPYEPESKQTVLQEYDILKSLHHEKIMALHEAYVTP-RYLVLISECCSGKELLHSLIDRFRYSEDDVVAYIVQILQGLDYLHSRRILHLDIKPENIIVT--YMNVVKIIDFGSA---QTFNPLFLKQFSPPIGTLDYMSPEMLKGDVVGPPADIWSIGILTYIMLSGRLPFTENDPAETEARIQAAKFDLSKLYQN-----VSQSASLFIKKILCSYPWARPTIKDCFTNSWL 3005 HSP 3 Score: 93.2041 bits (230), Expect = 7.545e-18 Identity = 116/515 (22.52%), Postives = 202/515 (39.22%), Query Frame = 2 Query: 5534 WLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKI-NESSVD-----ILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAE----NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDS---------------------SRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPIL--PPD-KPTIIFKDATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLS-LEPGVSYMFRVIAFNDFGISEPS 6973 WL+D + + + + +I++ + +D G+Y+ KI NE + VK RP + L I +P++D+ ++ ET FE V W + + I M F C L + + E G YT +++ + S +L ++ I PLFT+KL +E++ N R +C++ P P+++W+ L+ N ++IL E +LII+ ED G Y N G D A + V + P S R + P+ + +G + +L VA I + K + ST +K+ + +SL C+ + +CV ++ G T + + + + IL PPD P + + +SW K K L P +MY+++ + W I+++ L Y++S L GV Y FRV++ S+PS Sbjct: 630 WLRDRVTIKTGTRHIVQETEEGNFEMIIKSAQRSDTGVYTCKIINEYGTKQCEGKLEVKARP---------VEPGL---AIIRPVRDVMVKAG-ETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKRC----RLLLNSVHEDDSGTYTCKLSTAKEELTSSAKLKVI------------ASIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEE---NEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPRPAISSQIAKLEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREAVLR-CKVAGLPYPTITW-FHNGKRIDSTEDRKMTQ--FRDVHSLVVRCVCHAHGGVYKCVISNKVGKATCYSHLYV-----TDILPDPPDGAPVVESITGKTITLSWK--KPKRLDPSIDPSSLMYAIQQQALGSIQWTIIASCLKQTTYTISNLSKGVRYAFRVLSITSKAFSKPS 1101 HSP 4 Score: 89.7373 bits (221), Expect = 1.006e-16 Identity = 113/470 (24.04%), Postives = 192/470 (40.85%), Query Frame = 2 Query: 10781 VTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLV-LGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSV-DNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSV--FQNKIRNIHSL----KQALIFNRKWMLTSRQSNHFNDL-----HDLIKDISSDDIRMNVIREHYSTLSQKSSG-FAVLKLKNTNVN-------------------FPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSI----FKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVH 12079 VTL+C + GS ISW K+++ L D R+ + G I+ T+ D G++ C+A + L T TS+ +V L +P P V + L+ W P Y ++ R + N NW + V D Y + +L Y R+ NK G PYS + V + + + SL + NR M S ++ + I +R V ++ Y+ + +K+ G F V++ N EY + ++ E I + V +Y +L E C G LL L+ R YSE VV I Q+L + +LHS ++H +I+P I+++ +K+I + Q + L P I + +PE + +DIWS+GIL++++L+ +LP E+ ++++ Sbjct: 2525 VTLSCLPA--GSPHPHISWMKDKKPLEIDPRMNMISCPDGRQLLMIMKTTKKDAGLYECVA-ANPLATVTSSCVVSLARLPNSPGTPEVPQKYKNTALVVWRPS-DTTAPCTYSLE-RKTEGEN---NWLIVATGVADCYYNVLDLPAGASYRFRVACVNKAGQGPYSSLSEVVVLDSTVVLVTSLSPVGEGTGTPNR--MTPSGRATPSGRITPSGRRTPIGKPGDSTLRQGVPQKPYTFMDEKARGRFGVIRECRENATGNLYMAKIVPYEPESKQTVLQEYDILKSLHHEKIMALHEAYVTPRYL---VLISECCS--------------GKELLHSLIDRFRYSEDDVVAYIVQILQGLDYLHSRRILHLDIKPENIIVTYMNV----VKIIDFGSAQTFNPL----FLKQFSPPIGTLDYMSPEMLKGDVVGPPADIWSIGILTYIMLSGRLPFTENDPAETEAR 2959
BLAST of Serine/threonine kinase vs. Ensembl Zebrafish
Match: spega (striated muscle enriched protein kinase a [Source:NCBI gene;Acc:570504]) HSP 1 Score: 128.642 bits (322), Expect = 1.523e-28 Identity = 136/607 (22.41%), Postives = 258/607 (42.50%), Query Frame = 2 Query: 8708 REITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEG------WSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFI-----------IKNLEEDDFGE--YCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPE----------KKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEI--NNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAV---PKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF--IKPGNNLNAAL 10384 R I LSW P+ +D P + Y ++ W+ +++ + L + Y R++ T + KPS PT ++ + ++ P+ K ++ + +E + IT T N+ + +R + G + I ++ D G+ + A ++ + + L+ + P + + + + E +V +D +P P+++W ++ + SS+ T + +D+E SL++ D G Y+ A+N G K L V + ++ + + D Y K++ +G++S + V K+ Q F KF + E + + H++IV DA + +V+I +L L E IT+ + ES+V+ II QL++ + YLH++ + HLD+KPENI+M + + +++C F NA+ P E+ + T F APE++ PI ++D+W +G++T+LCL G E D+ + E + A FI K +L+ R +++ L H WF + G ++N L Sbjct: 949 RMILLSWKKPK---------NLDPSIDPASLMYVVQQQVLGSTQWTTIASSLTDTSYTVTSLSKGVCYSFRVLSTTGKTLSKPSQ-------------PTDLVQLVDRGEYFRKAPVII---DKPDIVYA--VENQPVTITITINHVQATCTWKRRGVVLVNKLGALEMTTPDDDQHALHIAKVKSTDVGQLIFMANNQYGSDLCTLQLVIAVPPIFETIMEDLDVCVGETCHFAVVVDGKPDPDILWYKDGVLLAESSHLTFVYDDRE---CSLVVLNAQPEDVGVYTCTAKNLAGSVSCKAELTVHTAQNVEEEEEQMEDEATILRRMRMLTDYYDIHKEIGRGAFSYVKRVKHKNDQ-SFAAKFISVRAKKKTCALRELALLAELDHKSIVRFHDAFE--KRRVVIILTELCHEELLERITKRTTILESEVQSIIRQLLEGIEYLHQNDIIHLDLKPENILMADQKTDQIRICDFGNALKVKPNEELYCKYG---TPEFIAPEIVNQSPISKSTDIWPVGVITYLCLTGVSPFAGENDRDTLLNIRNYNVAFEESMFKDLCREAKGFIIK-VLVSNKLRPDATECLLHPWFKSLTKGKSINTTL 1518 HSP 2 Score: 92.8189 bits (229), Expect = 1.115e-17 Identity = 71/257 (27.63%), Postives = 124/257 (48.25%), Query Frame = 2 Query: 9626 YYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAV---PKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDA----------ISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 Y + + A+G + + E +T FI K + E++ ++++ I+ + +A P +YLVLI E G + + + + E V I Q++Q + YLH ++ HLDIKP+NI++T ++K+ F +A P R++G T + APE+LKG+ + +D+WS+G+L+++ L G + QL ++A +S SA F++K L R T D L+H W Sbjct: 2682 YSFLDEKARGRFGVIRDCRENATGKMFIAKIIPYDQQTKQTIIKEYEILKSLRCERIMALHEAYITP-RYLVLITEYCSGKEILQNLIDRFCYSEDDVVGFIVQILQGLEYLHNCKILHLDIKPDNIMVTNL--NVIKIIDFGSAQRFNPLSLQQCSRYLG-TLEYMAPEMLKGDLVGPPADIWSLGVLSYIMLSGRHPFEDKDPQLTEAKIHEAKFDSTKLYPKVSQSASTFLKKILNSYPWCRPTIKDCLNHSWL 2934 HSP 3 Score: 80.1073 bits (196), Expect = 7.918e-14 Identity = 100/444 (22.52%), Postives = 176/444 (39.64%), Query Frame = 2 Query: 5756 IKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAE----NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPK-ESDSSRIIVKP--------------------LCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKPTIIFK-DATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSL-SLEPGVSYMFRVIAFNDFGISEPSQ--SLISRIDR 7000 I +P+QD+ ++ ET E + S A W + I M+F C F +A E G YT +++ + L ++ E PLFT+KL+ +E + + + +C++ P P++ WT + L + + IL+ + +L+IT E G Y + N G + A + V + P + SR+ P P+ E +G + +L Y+ K + STN +K+ + + + S C S + +CV ++ G + + + P PD P +I + +SW K KNL P +MY ++ + + W +++ L D Y++ SL GV Y FRV++ +S+PSQ L+ +DR Sbjct: 620 ITRPMQDVKVKAG-ETALLECFIAGSQAVDVDWLANGKLIQPALFDCKMQFDGHRCRLLFK----SAHENDSGCYTCKLSTAKEELICTANLLVIPSKE------------PLFTRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPL---VESDNIHILNVNGHHSLLITHVNKESEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSRLEKMPSIPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYH--NGKKIESTNDRKMTQYRDVHSLVIQSVCH--DHSGVYKCVISNKVGKAACYAHLYVAVSLPEP---PDGPPVIESVTGRMILLSWK--KPKNLDPSIDPASLMYVVQQQVLGSTQWTTIASSLTDTSYTVTSLSKGVCYSFRVLSTTGKTLSKPSQPTDLVQLVDR 1034 HSP 4 Score: 69.707 bits (169), Expect = 1.008e-10 Identity = 82/359 (22.84%), Postives = 147/359 (40.95%), Query Frame = 2 Query: 5609 LILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRN-------EPETVKFEFEVEESGAKKAIWFF-ENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLM-LRSEISEQM-----MESCC-------------IAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSV----ATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSS 6592 L+ + D+G Y+ K++ + +++ NL + K+PL F R E + +F+ +V + W E ++++N+ + + + + +L I ++ G YT N G S L + R IS M M S P F K L D+E++ + L CR+ P PKI W +G+ ++S + + D +L+I + SG Y C+ +N +G A + V S P+ D +I E G ++LSW + D +++Y ++ Q+ L ST W I +LT+T+Y+++S Sbjct: 676 LLFKSAHENDSGCYTCKLSTAKEELICTA--------------NLLVIPSKEPL---FTRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDNIHIL--NVNGHHSLLITHVNKESEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSRLEKMPSIPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIESTNDRKMTQYRDV---HSLVIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPEPPDGPPVI-----------ESVTGRMILLSWKKPKNLDPSIDPASLMYVVQ-QQVLGSTQWTTIASSLTDTSYTVTS 1000 HSP 5 Score: 64.3142 bits (155), Expect = 4.416e-9 Identity = 78/317 (24.61%), Postives = 130/317 (41.01%), Query Frame = 2 Query: 11417 SSDDIRMNVIREHYSTLSQKSSG-FAVLKLKNTNVNFPEYIV----------QRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPLVDFVN 12334 S +R V ++ YS L +K+ G F V++ N +I Q K +I + C RI H + + E+ G +L L+ R YSE VV I Q+L +++LH+ ++H +I+P I++ TN + IK+I + Q + Q+ + APE + +DIWSLG+LS+++L+ + P ED K+ + F + KL + S+S+ F+ L P R L HSW + T ++T L +F+ Sbjct: 2669 SETTLRQGVPQKPYSFLDEKARGRFGVIRDCRENATGKMFIAKIIPYDQQTKQTIIKEYEILKSLR-CERIMALHEAYITPRYL-------VLITEYCSGKEILQNLIDRFCYSEDDVVGFIVQILQGLEYLHNCKILHLDIKPDNIMV---TNLNV-IKIIDFGSAQRFNPLSLQQCSRYLGTLEYMAPEMLKGDLVGPPADIWSLGVLSYIMLSGRHP-FED-----------KDPQLTEAKIHEAKFDSTKL--YPKVSQSASTFLKKILNSYPWCRPTIKDCLNHSWLHDSYLKKLRRQTLTFTTTRLKEFMG 2959 HSP 6 Score: 63.929 bits (154), Expect = 6.771e-9 Identity = 58/219 (26.48%), Postives = 93/219 (42.47%), Query Frame = 2 Query: 11615 ILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVK---EQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFK 12262 I+ E+C L RIT R+ E V +IIRQLL I++LH N+++H +++P IL++ D K + C F +K +E + F APE +S +DIW +G++++L L P + +D D ++N N + SM + ++ F+ L S R +A L H WFK Sbjct: 1324 IILTELCHEELLERIT---------------KRTTILESEVQSIIRQLLEGIEYLHQNDIIHLDLKPENILMA-------DQKTDQIRICDFGNALKVKPNEELYCKYGTPEFIAPEIVNQSPISKSTDIWPVGVITYLCLTGVSPFAGE--NDRDTLLNIRNYNVAF-----------EESMFKDLCREAKGFIIKVL-VSNKLRPDATECLLHPWFK 1506
BLAST of Serine/threonine kinase vs. Ensembl Zebrafish
Match: spega (striated muscle enriched protein kinase a [Source:NCBI gene;Acc:570504]) HSP 1 Score: 128.642 bits (322), Expect = 1.536e-28 Identity = 136/607 (22.41%), Postives = 258/607 (42.50%), Query Frame = 2 Query: 8708 REITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEG------WSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFI-----------IKNLEEDDFGE--YCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPE----------KKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEI--NNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAV---PKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF--IKPGNNLNAAL 10384 R I LSW P+ +D P + Y ++ W+ +++ + L + Y R++ T + KPS PT ++ + ++ P+ K ++ + +E + IT T N+ + +R + G + I ++ D G+ + A ++ + + L+ + P + + + + E +V +D +P P+++W ++ + SS+ T + +D+E SL++ D G Y+ A+N G K L V + ++ + + D Y K++ +G++S + V K+ Q F KF + E + + H++IV DA + +V+I +L L E IT+ + ES+V+ II QL++ + YLH++ + HLD+KPENI+M + + +++C F NA+ P E+ + T F APE++ PI ++D+W +G++T+LCL G E D+ + E + A FI K +L+ R +++ L H WF + G ++N L Sbjct: 949 RMILLSWKKPK---------NLDPSIDPASLMYVVQQQVLGSTQWTTIASSLTDTSYTVTSLSKGVCYSFRVLSTTGKTLSKPSQ-------------PTDLVQLVDRGEYFRKAPVII---DKPDIVYA--VENQPVTITITINHVQATCTWKRRGVVLVNKLGALEMTTPDDDQHALHIAKVKSTDVGQLIFMANNQYGSDLCTLQLVIAVPPIFETIMEDLDVCVGETCHFAVVVDGKPDPDILWYKDGVLLAESSHLTFVYDDRE---CSLVVLNAQPEDVGVYTCTAKNLAGSVSCKAELTVHTAQNVEEEEEQMEDEATILRRMRMLTDYYDIHKEIGRGAFSYVKRVKHKNDQ-SFAAKFISVRAKKKTCALRELALLAELDHKSIVRFHDAFE--KRRVVIILTELCHEELLERITKRTTILESEVQSIIRQLLEGIEYLHQNYIIHLDLKPENILMADQKTDQIRICDFGNALKVKPNEELYCKYG---TPEFIAPEIVNQSPISKSTDIWPVGVITYLCLTGVSPFAGENDRDTLLNIRNYNVAFEESMFKDLCREAKGFIIK-VLVSNKLRPDATECLLHPWFKSLTKGKSINTTL 1518 HSP 2 Score: 91.2781 bits (225), Expect = 3.516e-17 Identity = 71/257 (27.63%), Postives = 124/257 (48.25%), Query Frame = 2 Query: 9626 YYTMKKLAKGSYSRCQIVIEKSTQIEFIGKF--FEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAV---PKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDA----------ISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 Y + + A+G + + E +T FI K ++ E++ ++++ I+ + +A P +YLVLI E G + + + + E V I Q++Q + YLH ++ HLDIKP+NI++T ++K+ F +A P R++G T + APE+LKG+ + +D+WS+G+L+++ L G + QL ++A +S SA F++K L R T D L H W Sbjct: 2682 YSFLDEKARGRFGVIRDCRENATGKMFIAKIIPYDQKTKQTIIKEYEILKSLRCERIMALHEAYITP-RYLVLITEYCSGKEILQNLIDRFCYSEDDVVGFIVQILQGLEYLHNCKILHLDIKPDNIMVTNL--NVIKIIDFGSAQRFNPLSLQQCSRYLG-TLEYMAPEMLKGDLVGPPADIWSLGVLSYIMLSGRHPFEDKDPQLTEAKIHEAKFDSTKLYPKVSQSASTFLKKILNSYPWCRPTIKDCLIHSWL 2934 HSP 3 Score: 80.1073 bits (196), Expect = 8.467e-14 Identity = 100/444 (22.52%), Postives = 176/444 (39.64%), Query Frame = 2 Query: 5756 IKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAE----NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPK-ESDSSRIIVKP--------------------LCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKPTIIFK-DATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSL-SLEPGVSYMFRVIAFNDFGISEPSQ--SLISRIDR 7000 I +P+QD+ ++ ET E + S A W + I M+F C F +A E G YT +++ + L ++ E PLFT+KL+ +E + + + +C++ P P++ WT + L + + IL+ + +L+IT E G Y + N G + A + V + P + SR+ P P+ E +G + +L Y+ K + STN +K+ + + + S C S + +CV ++ G + + + P PD P +I + +SW K KNL P +MY ++ + + W +++ L D Y++ SL GV Y FRV++ +S+PSQ L+ +DR Sbjct: 620 ITRPMQDVKVKAG-ETALLECFIAGSQAVDVDWLANGKLIQPALFDCKMQFDGHRCRLLFK----SAHENDSGCYTCKLSTAKEELICTANLLVIPSKE------------PLFTRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPL---VESDNIHILNVNGHHSLLITHVNKESEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSRLEKMPSIPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYH--NGKKIESTNDRKMTQYRDVHSLVIQSVCH--DHSGVYKCVISNKVGKAACYAHLYVAVSLPEP---PDGPPVIESVTGRMILLSWK--KPKNLDPSIDPASLMYVVQQQVLGSTQWTTIASSLTDTSYTVTSLSKGVCYSFRVLSTTGKTLSKPSQPTDLVQLVDR 1034 HSP 4 Score: 69.707 bits (169), Expect = 1.025e-10 Identity = 86/384 (22.40%), Postives = 154/384 (40.10%), Query Frame = 2 Query: 5534 WLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRN-------EPETVKFEFEVEESGAKKAIWFF-ENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLM-LRSEISEQM-----MESCC-------------IAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSV----ATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSS 6592 WL + KL+ + L+ + D+G Y+ K++ + +++ NL + K+PL F R E + +F+ +V + W E ++++N+ + + + + +L I ++ G YT N G S L + R IS M M S P F K L D+E++ + L CR+ P PKI W +G+ ++S + + D +L+I + SG Y C+ +N +G A + V S P+ D +I E G ++LSW + D +++Y ++ Q+ L ST W I +LT+T+Y+++S Sbjct: 651 WLANGKLIQPALFDCKMQFDGHRCRLLFKSAHENDSGCYTCKLSTAKEELICTA--------------NLLVIPSKEPL---FTRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDNIHIL--NVNGHHSLLITHVNKESEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSRLEKMPSIPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIESTNDRKMTQYRDV---HSLVIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPEPPDGPPVI-----------ESVTGRMILLSWKKPKNLDPSIDPASLMYVVQ-QQVLGSTQWTTIASSLTDTSYTVTS 1000 HSP 5 Score: 64.6994 bits (156), Expect = 4.027e-9 Identity = 78/317 (24.61%), Postives = 130/317 (41.01%), Query Frame = 2 Query: 11417 SSDDIRMNVIREHYSTLSQKSSG-FAVLKLKNTNVNFPEYIV----------QRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPLVDFVN 12334 S +R V ++ YS L +K+ G F V++ N +I Q K +I + C RI H + + E+ G +L L+ R YSE VV I Q+L +++LH+ ++H +I+P I++ TN + IK+I + Q + Q+ + APE + +DIWSLG+LS+++L+ + P ED K+ + F + KL + S+S+ F+ L P R L HSW + T ++T L +F+ Sbjct: 2669 SETTLRQGVPQKPYSFLDEKARGRFGVIRDCRENATGKMFIAKIIPYDQKTKQTIIKEYEILKSLR-CERIMALHEAYITPRYL-------VLITEYCSGKEILQNLIDRFCYSEDDVVGFIVQILQGLEYLHNCKILHLDIKPDNIMV---TNLNV-IKIIDFGSAQRFNPLSLQQCSRYLGTLEYMAPEMLKGDLVGPPADIWSLGVLSYIMLSGRHP-FED-----------KDPQLTEAKIHEAKFDSTKL--YPKVSQSASTFLKKILNSYPWCRPTIKDCLIHSWLHDSYLKKLRRQTLTFTTTRLKEFMG 2959 HSP 6 Score: 62.3882 bits (150), Expect = 2.013e-8 Identity = 58/219 (26.48%), Postives = 92/219 (42.01%), Query Frame = 2 Query: 11615 ILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVK---EQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFK 12262 I+ E+C L RIT R+ E V +IIRQLL I++LH N ++H +++P IL++ D K + C F +K +E + F APE +S +DIW +G++++L L P + +D D ++N N + SM + ++ F+ L S R +A L H WFK Sbjct: 1324 IILTELCHEELLERIT---------------KRTTILESEVQSIIRQLLEGIEYLHQNYIIHLDLKPENILMA-------DQKTDQIRICDFGNALKVKPNEELYCKYGTPEFIAPEIVNQSPISKSTDIWPVGVITYLCLTGVSPFAGE--NDRDTLLNIRNYNVAF-----------EESMFKDLCREAKGFIIKVL-VSNKLRPDATECLLHPWFK 1506
BLAST of Serine/threonine kinase vs. Ensembl Zebrafish
Match: si:dkey-240h12.4 (si:dkey-240h12.4 [Source:ZFIN;Acc:ZDB-GENE-070705-406]) HSP 1 Score: 119.398 bits (298), Expect = 7.498e-28 Identity = 84/284 (29.58%), Postives = 150/284 (52.82%), Query Frame = 2 Query: 9605 IGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEI-----NNMGIGRS----EFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNA---VPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ--LYNEDSND---------AISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAA 10381 + +V D Y L G + + + V E++T + + GKF ++ + +G+ R E + +Q++ H+NI+ I D + +VLI E ++G L ++I + + E++ + Q+++ V+Y+H+ V H D+KPENI+++ K++ +K+ F A + E++ S +G T + APE++ EP+ +DMWSIG++T++ L G E D+ L N S + +N A FI+K L+ ER+T+ + L H W IKP N A Sbjct: 6 VDNVEDLYEIGNVLGSGHFGQVREVRERATGVLWAGKFLKLKKGAGSRLGLERKSVEKEVEILQSLQHQNIMAIRDVFESRAE-IVLIVELIKGGELFDFIAEKENLTETEAIEFMKQILEGVNYMHQKNVAHFDLKPENIMLSDKHDPHPDIKIIDFGMAHHFIQGEEYKS---LGGTPQYIAPEIINYEPLGTAADMWSIGVITYILLSGLSPFQGETDEETLRNIVSMNYEFEPHFFSQTTNMAKDFIQKLLVKDQSERMTAEECLIHPW-IKPLNRTQIA 284 HSP 2 Score: 67.3958 bits (163), Expect = 1.530e-10 Identity = 48/203 (23.65%), Postives = 91/203 (44.83%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYE-----SDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFK 12262 E + GG L + + +E + ++Q+L + ++H NV H +++P I++S + + DIK+I +E +SL P+Y I YE +D+WS+G+++++LL+ P +D + + + N P HF + +M ++ F+ L K ++R A+ L H W K Sbjct: 94 ELIKGGELFDFIAEKENLTETEAIEFMKQILEGVNYMHQKNVAHFDLKPENIMLSDKHDPHPDIKIIDFGMAHHFIQGEEYKSLGG-------TPQYIAPEIINYEPLGTAADMWSIGVITYILLSGLSPF--QGETDEETLRNIVSMNYEFEP----HFFSQTTNM-------AKDFIQKLLVKDQSERMTAEECLIHPWIK 276
BLAST of Serine/threonine kinase vs. Ensembl Zebrafish
Match: obscna (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF a [Source:ZFIN;Acc:ZDB-GENE-040812-4]) HSP 1 Score: 123.25 bits (308), Expect = 6.223e-27 Identity = 96/352 (27.27%), Postives = 169/352 (48.01%), Query Frame = 2 Query: 9362 IDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIG-----DVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRS--EFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGL---TSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ----------LYNEDSNDAISNS--ACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 I P PE+ W ++ +I SS TVI ++ + + +LL ++ D G Y+ A N+ G L VD PE+ + ++ Y +++ +G++ + V K++ F KF + + R+ E + ++HR + + D + + LVL+ E SL +++ E +V++ I Q+++ + Y+H + HLDIK +NI+M E +K+C F ++ S RH T F APE++ EP+ +D+WS+G++ +LCL H E D+ LY D+ + S S A F+ + L +R ++S+ LSHEWF Sbjct: 593 ITGHPRPEIQWFKDDVEISSSEYTVIVQNGARCSLTLLDTQT--EDCGTYTCIASNSAGQVFCHAQLNVDTGPEEIEESREVEFGKRRKLHSVYDVYEEIGRGTFGVVKKVTHKASGECFAAKFLPLRSSTRTRAFQERDLLSRLAHRRLACLLDFFST-RRTLVLVVELCSSQSLLDHLFLKGSVTEREVQLYIQQVLEGIGYIHGMNILHLDIKTDNILMVSPTREDIKICDFGFC---QEVDSSRHQYSKFGTPEFIAPEIVHQEPVTAATDIWSLGVVAYLCLTCHCPFFGENDRATLMKVAEGVLY-WDTPEITSRSVEAQDFLHRVLQPDPEKRPSASECLSHEWF 937 HSP 2 Score: 88.1965 bits (217), Expect = 2.928e-16 Identity = 61/221 (27.60%), Postives = 113/221 (51.13%), Query Frame = 2 Query: 9752 EFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVP------------KEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHG----HLKVNFEGDQLYNEDS------NDAISNSACVFIRKCLLLKTGERLTSSDSLSHEW 10348 E+Q ++ +SH IV++ AI + L+LI E G L + + + + E+ V ++ Q++ AV YLH R+ HLD+K +N+++TGK ++K+ +A P +E ++ ++ L APE+L+G+ + +D+W+IG+L F+ L H +N+E D+ + +S A F++ L K R T+++ L + W Sbjct: 1733 EYQVLRRLSHPRIVQLHSAI-LTSTCLLLIEELCSGRELLYNLAERNLYSEAHVTDLLEQILSAVDYLHSRRIVHLDLKSDNMLVTGK--NLVKIVDLGSAQPFNPGQALNIEHIREMTDNKGYIVLP---KAPEILEGQGVGPETDIWAIGVLAFIMLSADSPFHADLNWERDRNIKKGKIQFSRCYPGLSEGAINFMKNTLSNKAWARPTAAECLQNPW 1947 HSP 3 Score: 68.1662 bits (165), Expect = 3.009e-10 Identity = 57/208 (27.40%), Postives = 95/208 (45.67%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEME 12292 E +LL L + +E V I+Q+L I ++H N++H +I+ IL+ T + DIK+ CQ V + + Q S F APE ++ +DIWSLG++++L L P ++D +K +L ++ P+++ S ++ F+H L+ P R +A L+H WF Q YE E Sbjct: 758 ELCSSQSLLDHLFLKGSVTEREVQLYIQQVLEGIGYIHGMNILHLDIKTDNILMVSPTRE--DIKICDFGFCQEVDSSRHQYS--KFGTPEFIAPEIVHQEPVTAATDIWSLGVVAYLCLTCHCPFF----GENDRATLMKVAEGVL------YWDTPEITSR---SVEAQDFLHRVLQPDPEKRPSASECLSHEWF----QGYYEDE 944 HSP 4 Score: 60.8474 bits (146), Expect = 5.340e-8 Identity = 38/136 (27.94%), Postives = 70/136 (51.47%), Query Frame = 2 Query: 11657 ITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVG-----TVKEQESLTTHKPSIF--KAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 + EE G LL L R++YSE V ++ Q+L + +LHS +VH +++ +L++ + +K++ L + Q ++ +T +K I KAPE E+DIW++G+L+F++L+ P Sbjct: 1759 LLIEELCSGRELLYNLAERNLYSEAHVTDLLEQILSAVDYLHSRRIVHLDLKSDNMLVTGKNL----VKIVDLGSAQPFNPGQALNIEHIREMTDNKGYIVLPKAPEILEGQGVGPETDIWAIGVLAFIMLSADSP 1890
BLAST of Serine/threonine kinase vs. Ensembl Xenopus
Match: phyh (phytanoyl-CoA 2-hydroxylase [Source:Xenbase;Acc:XB-GENE-943669]) HSP 1 Score: 131.724 bits (330), Expect = 2.598e-29 Identity = 141/591 (23.86%), Postives = 240/591 (40.61%), Query Frame = 2 Query: 8708 REITLSWSPP-RISPDLYIP-FTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIY-----------FIIKNLEEDDFGE--YCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQI-NIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKF--FEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSP-FSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGE--------------RLTSSDSLSHEWFIKPGNNLNA 10378 R + L W PP R+ P + + T V+ + V W+V TN+K + L Y R+ T KPS P +E + L + + E+ + ++E + IT T N+ V +R + G+Y + + D G+ + A + + + ++AP + + + + + E V ++ +P P+++W ++ + S + + + +D E SL+I L D G Y+ A N G K L+V E + I + + D Y K++ +G++S + V+EKS + KF F R E + + H I+ +DA L+++ E Y + + E +R I Q+++ + YLH + HLDIKPENI+M +E +++C F NA + G ++ +P F APE++ PI +D+W +G+L +LCL G F G+ Y N I F K + T E R + +SL H WF NNLN Sbjct: 516 RIVKLQWKPPKRLDPAIDLAQITYSVQQQAVGSPQ-----WTVIATNLKDTCYCVRSLTKEHQYLFRVTTNTPTSHSKPS--------------PPSESVCLFNRGPYLE--EMPSILDRPEILY--MVENQPLCITVTLNHVHAKVTWQRIDTVLSNVEGVYELSMPDDDQHSLTFFSPRKSDLGQLTFEAKNRYGSDSCTISIELAEAPRFESIMEDIEIGVGETARFVVVVEGKPIPDIMWYKDGVLLAESGHFSFVYDDTE---CSLVILNTALGDSGVYTCTARNLSGEISCKAELQVCPGKEPNEIDILKVRRLTDFYNIHKEIGRGAFSYVRHVVEKSNGRDLAAKFIPFRGATRESARRERDILSKLRHDRIIFFYDAFEK-RSALIIVMEL--------YPQKRAEVLEPHIRSFIRQILEGLDYLHHKNILHLDIKPENILMADTTSEQIRICDFGNAQ-ELTPGDPQYCKYGTPEFVAPEIVNQMPISTVTDIWPVGVLAYLCLTG--VSPFVGENDYTTLMN--IRGYTVAFEEKMFVGLTREARGFLIKVLGNEKLRPNAEESLEHPWFKVSVNNLNG 1066 HSP 2 Score: 100.908 bits (250), Expect = 6.079e-20 Identity = 75/270 (27.78%), Postives = 128/270 (47.41%), Query Frame = 2 Query: 9584 KKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKF--FEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYN-EILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDS-----------NDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 ++S + G Y + + A+G + + E +T F+ K +E N E++ ++ + H+ I+ + +A P +YLVLI E G L + + + E V + Q++Q + YLHE +V HLDIKPEN+I++ +I+ L N P + +G T + +PE+LKG+ + +D+W +G+LT++ L G FE D + E S SA +FIRK L + R + + S+ W Sbjct: 2104 RESTTLRQGVPQKPYTFLDEKARGRFGVIRECKENATGKHFMAKIIQYEPENKQNVLQEYEILKGLHHQRILSLHEAYITP-RYLVLISENCTGRELLYCLVERFRYSEDDVVNYLLQILQGLEYLHEQKVLHLDIKPENVIVSYMNTVKIIDLGSAQNFTPLVLRPLGKRIG-TLEYMSPEMLKGDAVGPAADIWGVGVLTYIMLSGRSPF-FELDPVETEHKILSGRFDIFKLYSNASQSASLFIRKILTIYPWSRPSLKECFSNPWL 2370 HSP 3 Score: 63.5438 bits (153), Expect = 1.025e-8 Identity = 56/218 (25.69%), Postives = 90/218 (41.28%), Query Frame = 2 Query: 5753 QIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAE----NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRI 6394 ++ PLQD+ + E FE V W F + + M F C L + + E G YT +++ R + S ML S +APLFT+KL D +++ RL+C++ P P + WT G+ ++ + + +L E + TL+I ED G+Y N G A + V EP+ + +S I Sbjct: 186 EVLAPLQDVSV-CAGEAAVFECVVSGPADMDVDWMFRGKLLQPALLDCKMRFNGKQC----VLLLNSVHEDDSGVYTCKLST----ARDELTCSAMLTVHPS--------LAPLFTRKLSDRDVIEGRTARLDCKISGTPPPVVTWTHFGQPIEE---SENIHVLREGGHHTLLIPHVANEDEGQYTATAHNKHGEAECSAELYV--EEPRSATASHI 381 HSP 4 Score: 59.3066 bits (142), Expect = 2.361e-7 Identity = 81/368 (22.01%), Postives = 141/368 (38.32%), Query Frame = 2 Query: 5609 LILRDVKMTDAGMYSLKI----NESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEID-AENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSL-----MLRSEIS----------EQMMESC----CIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSV----ATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLR 6628 L+L V D+G+Y+ K+ +E + ++ V P P + L D + E T + + ++ + W + I+ +EN+ ++ + L IP + G+YT N G L + S IS E M+ C + P F + L+DI+++ ++L C++ P P I W +G+ + S R + D L+ +G Y + +N +G A + VTD P D P++T+ G V L W D I Y+++ Q+++ S W I NL +T Y + S L + +L R Sbjct: 243 LLLNSVHEDDSGVYTCKLSTARDELTCSAMLTVHPS-------------LAPLFTRKLSDRDV-IEGRTARLDCKISGTPPPVVTWTHFGQPIEESENIHVLREG--GHHTLLIPHVANEDEGQYTATAHNKHGEAECSAELYVEEPRSATASHISKLEKMPSIPEEPEMQECEVEGVMMPDFLRPLQDIDVVEFREVQLECQVTGLPYPTITWYHNGQKIQSSDDRRMTQYKD---IHRLVFPSVTHSHAGVYKSVISNKVGKAACYAHLYVTDLVPTPPDG---------PPIITS--VTGRIVKLQWKPPKRLDPAIDLAQITYSVQ-QQAVGSPQWTVIATNLKDTCYCVRS--LTKEHQYLFR 577
BLAST of Serine/threonine kinase vs. Ensembl Xenopus
Match: c7orf26 (chromosome 7 open reading frame 26 [Source:Xenbase;Acc:XB-GENE-5734232]) HSP 1 Score: 116.316 bits (290), Expect = 1.377e-26 Identity = 82/287 (28.57%), Postives = 137/287 (47.74%), Query Frame = 2 Query: 9587 KSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFE-----INNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH---------------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNN 10369 K V+ V D Y +L G ++ + E+ T +E+ KF + + G+ R E + +++I H+NI+ + D +VLI E + G L +++ Q E + I Q+++ V+YLH ++ H D+KPENI++ K + +KL F A ED +++ T F APE++ EP+ +DMWSIG++T++ L G VN+E ++E+ S A FIRK L+ T +RL+ ++L H W N Sbjct: 5 KMVEFKQQKVEDFYDIADELGSGQFAIVKRCRERKTGVEYAAKFIKKRQSPASRRGVIRGEIEREVDILKDIQHQNIITLQDVYENKTD-VVLILELVSGGELFDFLAQKESLSEEEATRFIKQILEGVNYLHTRKIAHFDLKPENIMLLDKTIPMPHIKLIDFGLAHTIEDGVEFKNIFGTPEFVAPEIVNYEPLGLAADMWSIGVITYILLSGASPFLGENKQETLSNITAVNYE----FDEEFFSHTSELAKDFIRKLLVKDTRKRLSIQEALRHPWITPRDKN 286 HSP 2 Score: 60.8474 bits (146), Expect = 2.252e-8 Identity = 38/130 (29.23%), Postives = 62/130 (47.69%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYE-----SDIWSLGILSFLLLATQLP 12043 E V GG L L + SE I+Q+L + +LH+ + H +++P I++ +T IKLI G E K +IF PE+ I YE +D+WS+G+++++LL+ P Sbjct: 99 ELVSGGELFDFLAQKESLSEEEATRFIKQILEGVNYLHTRKIAHFDLKPENIMLLDKTIPMPHIKLIDF------GLAHTIEDGVEFK-NIFGTPEFVAPEIVNYEPLGLAADMWSIGVITYILLSGASP 221
BLAST of Serine/threonine kinase vs. Ensembl Xenopus
Match: nek2 (NIMA-related kinase 2 [Source:NCBI gene;Acc:407849]) HSP 1 Score: 115.546 bits (288), Expect = 3.612e-26 Identity = 81/279 (29.03%), Postives = 136/279 (48.75%), Query Frame = 2 Query: 9611 DVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEI-----NNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGK--YNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAA 10381 +V D Y ++KL G + + EKST + GKF + + +G+ R + + +Q + H NI+ + D A + +VLI E ++G L ++I + E + Q+++ V+Y+H + H D+KPENI++ K + +K+ F A ED + + T + APE++ EP+ +DMWSIG++T++ L G E DQ +++ S A FIR+ LL +R+T+ + L H W IKP N A Sbjct: 8 NVEDLYELLEKLGSGHFGEVKKCKEKSTGTYYAGKFIKTRKCKGSRLGLDRDQVEREVFILQQLEHPNIMRLHDVFASKAE-MVLILELIRGGELFDFIAEKEALSEEDAIEFLEQILKGVAYMHTRSIAHFDLKPENIMLLQKDVPHPKIKIIDFGLAQKIEDGTVFKSLCGTPQYIAPEVINYEPLGPPTDMWSIGVITYILLSGLSPFQGETDQETLTNVVAGSYEFDDRIFKQTSELAKDFIRQLLLKDPRDRMTAVECLIHPW-IKPLNRKQAV 284 HSP 2 Score: 62.003 bits (149), Expect = 1.126e-8 Identity = 46/203 (22.66%), Postives = 91/203 (44.83%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYE-----SDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFK 12262 E + GG L + + SE + + Q+L + ++H+ ++ H +++P I++ ++ IK+I G ++ E T K S+ P+Y + YE +D+WS+G+++++LL+ P + + TL V ++ ++ + S+ ++ F+ L K P DR A L H W K Sbjct: 94 ELIRGGELFDFIAEKEALSEEDAIEFLEQILKGVAYMHTRSIAHFDLKPENIMLLQKDVPHPKIKIIDF------GLAQKIEDGTVFK-SLCGTPQYIAPEVINYEPLGPPTDMWSIGVITYILLSGLSPFQGET-----------DQETLTNVVAGSYEFDDRI--FKQTSELAKDFIRQLLLKDPRDRMTAVECLIHPWIK 276
BLAST of Serine/threonine kinase vs. Ensembl Xenopus
Match: nek2 (NIMA-related kinase 2 [Source:NCBI gene;Acc:407849]) HSP 1 Score: 115.546 bits (288), Expect = 6.874e-26 Identity = 81/278 (29.14%), Postives = 136/278 (48.92%), Query Frame = 2 Query: 9611 DVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEI-----NNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGK--YNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNA 10378 +V D Y ++KL G + + EKST + GKF + + +G+ R + + +Q + H NI+ + D A + +VLI E ++G L ++I + E + Q+++ V+Y+H + H D+KPENI++ K + +K+ F A ED + + T + APE++ EP+ +DMWSIG++T++ L G E DQ +++ S A FIR+ LL +R+T+ + L H W IKP N A Sbjct: 52 NVEDLYELLEKLGSGHFGEVKKCKEKSTGTYYAGKFIKTRKCKGSRLGLDRDQVEREVFILQQLEHPNIMRLHDVFASKAE-MVLILELIRGGELFDFIAEKEALSEEDAIEFLEQILKGVAYMHTRSIAHFDLKPENIMLLQKDVPHPKIKIIDFGLAQKIEDGTVFKSLCGTPQYIAPEVINYEPLGPPTDMWSIGVITYILLSGLSPFQGETDQETLTNVVAGSYEFDDRIFKQTSELAKDFIRQLLLKDPRDRMTAVECLIHPW-IKPLNRKQA 327 HSP 2 Score: 61.6178 bits (148), Expect = 1.816e-8 Identity = 46/203 (22.66%), Postives = 91/203 (44.83%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYE-----SDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFK 12262 E + GG L + + SE + + Q+L + ++H+ ++ H +++P I++ ++ IK+I G ++ E T K S+ P+Y + YE +D+WS+G+++++LL+ P + + TL V ++ ++ + S+ ++ F+ L K P DR A L H W K Sbjct: 138 ELIRGGELFDFIAEKEALSEEDAIEFLEQILKGVAYMHTRSIAHFDLKPENIMLLQKDVPHPKIKIIDF------GLAQKIEDGTVFK-SLCGTPQYIAPEVINYEPLGPPTDMWSIGVITYILLSGLSPFQGET-----------DQETLTNVVAGSYEFDDRI--FKQTSELAKDFIRQLLLKDPRDRMTAVECLIHPWIK 320
BLAST of Serine/threonine kinase vs. Ensembl Xenopus
Match: nek2 (NIMA-related kinase 2 [Source:NCBI gene;Acc:407849]) HSP 1 Score: 115.161 bits (287), Expect = 7.298e-26 Identity = 81/278 (29.14%), Postives = 136/278 (48.92%), Query Frame = 2 Query: 9611 DVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEI-----NNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGK--YNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNA 10378 +V D Y ++KL G + + EKST + GKF + + +G+ R + + +Q + H NI+ + D A + +VLI E ++G L ++I + E + Q+++ V+Y+H + H D+KPENI++ K + +K+ F A ED + + T + APE++ EP+ +DMWSIG++T++ L G E DQ +++ S A FIR+ LL +R+T+ + L H W IKP N A Sbjct: 52 NVEDLYELLEKLGSGHFGEVKKCKEKSTGTYYAGKFIKTRKCKGSRLGLDRDQVEREVFILQQLEHPNIMRLHDVFASKAE-MVLILELIRGGELFDFIAEKEALSEEDAIEFLEQILKGVAYMHTRSIAHFDLKPENIMLLQKDVPHPKIKIIDFGLAQKIEDGTVFKSLCGTPQYIAPEVINYEPLGPPTDMWSIGVITYILLSGLSPFQGETDQETLTNVVAGSYEFDDRIFKQTSELAKDFIRQLLLKDPRDRMTAVECLIHPW-IKPLNRKQA 327 HSP 2 Score: 62.003 bits (149), Expect = 1.486e-8 Identity = 46/203 (22.66%), Postives = 91/203 (44.83%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYE-----SDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFK 12262 E + GG L + + SE + + Q+L + ++H+ ++ H +++P I++ ++ IK+I G ++ E T K S+ P+Y + YE +D+WS+G+++++LL+ P + + TL V ++ ++ + S+ ++ F+ L K P DR A L H W K Sbjct: 138 ELIRGGELFDFIAEKEALSEEDAIEFLEQILKGVAYMHTRSIAHFDLKPENIMLLQKDVPHPKIKIIDF------GLAQKIEDGTVFK-SLCGTPQYIAPEVINYEPLGPPTDMWSIGVITYILLSGLSPFQGET-----------DQETLTNVVAGSYEFDDRI--FKQTSELAKDFIRQLLLKDPRDRMTAVECLIHPWIK 320
BLAST of Serine/threonine kinase vs. Ensembl Mouse
Match: Speg (SPEG complex locus [Source:MGI Symbol;Acc:MGI:109282]) HSP 1 Score: 124.02 bits (310), Expect = 4.712e-27 Identity = 139/623 (22.31%), Postives = 263/623 (42.22%), Query Frame = 2 Query: 8708 REITLSWSPPRISPDLYIPFTVDVECRPVNYSYS------DEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDV--NDERYKIFSAETYGIYFIIKNLEEDDFGEYC-----------------ALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGD-------------VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFF--EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIM--TGKYNEILKLCGFSNA---VPKE----DFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYI 10393 R +TLSW+PPR ++D+ P + +Y+ + W+ T +++ L I + R++ + KPS + ++ ++ P E+A + +K ++E + +T TFN+ + V R + A T G+Y L + D +YC A + S L ++AP + + + + E +V ++ +P P+++W ++ + S++ + + E+ E SL++ DGG Y+ A N G K L V S Q + ++D Y +++ +G++S + V+E+S+ +EF KF + R E + + + H ++ +A + LV++ E L L E + + CES+ R + Q+++ + YLH+ V HLD+KPEN+++ E +++C F NA P E +G T F APE++ P+ +D+W +G++ FLCL G E D+ + E + ++S A F+ K +L++ R T+ ++L H WF + D++ Sbjct: 1302 RMVTLSWNPPR---------SLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPAWAATGLKKGIQHIFRVLSSSGKSSSKPSAPSEPVQLLEH--GPPLEEAPAVLDKQ----------------DIVYVVEGQPACVTVTFNHVEAQVVWRSCRGALLEART-GVY----ELSQPDDDQYCLRICRVSRRDLGPLTCSARNRHGTKACSVTLELAEAPRFESIMEDVEVGPGETARFAVVVEGKPLPDIMWYKDEVLLAESNHVSFVYEENE---CSLVLLSAGSQDGGVYTCTARNLAGEVSCKAELSV------LSAQTAMEVEGVGEDEEHRGRRLSDYYDIHQEIGRGAFSYLRRVVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHGCVLYFHEAFER-RRGLVIVTE-LCTEELLERMARKPTVCESETRTYMRQVLEGICYLHQSHVLHLDVKPENLLVWDGAGGEEQVRICDFGNAQELTPGEPQYCQYG-------TPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIK-VLVQDRLRPTAEETLEHPWFKTEAKGAEVSTDHL 1873 HSP 2 Score: 117.857 bits (294), Expect = 3.501e-25 Identity = 79/281 (28.11%), Postives = 130/281 (46.26%), Query Frame = 2 Query: 9566 VDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVP--KEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH---------------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 V + P +S + G Y +++ A+G + + E +T F+ K G R E++ ++ + H ++ + +A P +YLVLI E L ++ + E V + QL+Q + YLH H V HLDIKP+N+++ + LK+ F +A P + H T F APE++KG+PI +D+W G+LT++ L G+ + F+ QLY S SA +F+RK L + R + D L+H W Sbjct: 2941 VVSSPTPESTTLRQGPPQKPYTFLEEKARGRFGVVRSCRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERLMSLHEAYITP-RYLVLIAESCGNRELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGHHVLHLDIKPDNLLLAA--DNALKIVDFGSAQPYNPQALKPLGHRTGTLEFMAPEMVKGDPIGSATDIWGAGVLTYIMLSGYSPFYEPDPQETEARIVGGRFDAFQLYPN-----TSQSATLFLRKVLSVHPWSRPSLQDCLAHPWL 3213 HSP 3 Score: 55.0694 bits (131), Expect = 3.509e-6 Identity = 36/120 (30.00%), Postives = 58/120 (48.33%), Query Frame = 2 Query: 6074 APLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAE 6433 AP+F L+++ + ++ L C + +P P++ W KDG L S+ R+ I E TL++ EA+ D+G Y TN LG T + + V P S S P +P+ + E Sbjct: 726 APVFEIPLQNMVVAPGADVLLKCIITANPPPQVSWKKDGSMLHSE---GRLLIRAEGERHTLLLREAQAADAGSYTATATNELGQATCASSLAV---RPGGSTS------PFSSPITSDE 833 HSP 4 Score: 53.9138 bits (128), Expect = 7.214e-6 Identity = 66/265 (24.91%), Postives = 108/265 (40.75%), Query Frame = 2 Query: 11528 EYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLE---NCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISST 12313 EY V RT E + + + +Y +L E C GNR LL L R YSE V T + QLL + +LH ++V+H +I+P +L++ + + I G N Q + + + F APE +DIW G+L++++L+ P E +++ + L P+T S+S+ F+ L P R + LAH W QD + ++ QT++ T Sbjct: 3005 EYEVLRTLHHERLMSLHEAYITPRYL---VLIAESC----GNR----------ELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGHHVLHLDIKPDNLLLA--ADNALKIVDFGSAQPYNPQALKPLGHRTGTLE-----FMAPEMVKGDPIGSATDIWGAGVLTYIMLSGYSPFYEPDPQETEARIVGGRFDAFQL-YPNT-------------SQSATLFLRKVLSVHPWSRPSLQDCLAHPWL-QD-AYLMKLRRQTLTFT 3229
BLAST of Serine/threonine kinase vs. Ensembl Mouse
Match: Speg (SPEG complex locus [Source:MGI Symbol;Acc:MGI:109282]) HSP 1 Score: 123.635 bits (309), Expect = 5.339e-27 Identity = 139/623 (22.31%), Postives = 263/623 (42.22%), Query Frame = 2 Query: 8708 REITLSWSPPRISPDLYIPFTVDVECRPVNYSYS------DEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDV--NDERYKIFSAETYGIYFIIKNLEEDDFGEYC-----------------ALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGD-------------VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFF--EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIM--TGKYNEILKLCGFSNA---VPKE----DFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYI 10393 R +TLSW+PPR ++D+ P + +Y+ + W+ T +++ L I + R++ + KPS + ++ ++ P E+A + +K ++E + +T TFN+ + V R + A T G+Y L + D +YC A + S L ++AP + + + + E +V ++ +P P+++W ++ + S++ + + E+ E SL++ DGG Y+ A N G K L V S Q + ++D Y +++ +G++S + V+E+S+ +EF KF + R E + + + H ++ +A + LV++ E L L E + + CES+ R + Q+++ + YLH+ V HLD+KPEN+++ E +++C F NA P E +G T F APE++ P+ +D+W +G++ FLCL G E D+ + E + ++S A F+ K +L++ R T+ ++L H WF + D++ Sbjct: 1050 RMVTLSWNPPR---------SLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPAWAATGLKKGIQHIFRVLSSSGKSSSKPSAPSEPVQLLEH--GPPLEEAPAVLDKQ----------------DIVYVVEGQPACVTVTFNHVEAQVVWRSCRGALLEART-GVY----ELSQPDDDQYCLRICRVSRRDLGPLTCSARNRHGTKACSVTLELAEAPRFESIMEDVEVGPGETARFAVVVEGKPLPDIMWYKDEVLLAESNHVSFVYEENE---CSLVLLSAGSQDGGVYTCTARNLAGEVSCKAELSV------LSAQTAMEVEGVGEDEEHRGRRLSDYYDIHQEIGRGAFSYLRRVVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHGCVLYFHEAFER-RRGLVIVTE-LCTEELLERMARKPTVCESETRTYMRQVLEGICYLHQSHVLHLDVKPENLLVWDGAGGEEQVRICDFGNAQELTPGEPQYCQYG-------TPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIK-VLVQDRLRPTAEETLEHPWFKTEAKGAEVSTDHL 1621 HSP 2 Score: 117.472 bits (293), Expect = 3.809e-25 Identity = 79/281 (28.11%), Postives = 130/281 (46.26%), Query Frame = 2 Query: 9566 VDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVP--KEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH---------------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 V + P +S + G Y +++ A+G + + E +T F+ K G R E++ ++ + H ++ + +A P +YLVLI E L ++ + E V + QL+Q + YLH H V HLDIKP+N+++ + LK+ F +A P + H T F APE++KG+PI +D+W G+LT++ L G+ + F+ QLY S SA +F+RK L + R + D L+H W Sbjct: 2689 VVSSPTPESTTLRQGPPQKPYTFLEEKARGRFGVVRSCRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERLMSLHEAYITP-RYLVLIAESCGNRELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGHHVLHLDIKPDNLLLAA--DNALKIVDFGSAQPYNPQALKPLGHRTGTLEFMAPEMVKGDPIGSATDIWGAGVLTYIMLSGYSPFYEPDPQETEARIVGGRFDAFQLYPN-----TSQSATLFLRKVLSVHPWSRPSLQDCLAHPWL 2961 HSP 3 Score: 54.6842 bits (130), Expect = 3.637e-6 Identity = 36/120 (30.00%), Postives = 58/120 (48.33%), Query Frame = 2 Query: 6074 APLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAE 6433 AP+F L+++ + ++ L C + +P P++ W KDG L S+ R+ I E TL++ EA+ D+G Y TN LG T + + V P S S P +P+ + E Sbjct: 474 APVFEIPLQNMVVAPGADVLLKCIITANPPPQVSWKKDGSMLHSE---GRLLIRAEGERHTLLLREAQAADAGSYTATATNELGQATCASSLAV---RPGGSTS------PFSSPITSDE 581 HSP 4 Score: 53.9138 bits (128), Expect = 7.541e-6 Identity = 66/265 (24.91%), Postives = 108/265 (40.75%), Query Frame = 2 Query: 11528 EYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLE---NCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISST 12313 EY V RT E + + + +Y +L E C GNR LL L R YSE V T + QLL + +LH ++V+H +I+P +L++ + + I G N Q + + + F APE +DIW G+L++++L+ P E +++ + L P+T S+S+ F+ L P R + LAH W QD + ++ QT++ T Sbjct: 2753 EYEVLRTLHHERLMSLHEAYITPRYL---VLIAESC----GNR----------ELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGHHVLHLDIKPDNLLLA--ADNALKIVDFGSAQPYNPQALKPLGHRTGTLE-----FMAPEMVKGDPIGSATDIWGAGVLTYIMLSGYSPFYEPDPQETEARIVGGRFDAFQL-YPNT-------------SQSATLFLRKVLSVHPWSRPSLQDCLAHPWL-QD-AYLMKLRRQTLTFT 2977
BLAST of Serine/threonine kinase vs. Ensembl Mouse
Match: Dapk2 (death-associated protein kinase 2 [Source:MGI Symbol;Acc:MGI:1341297]) HSP 1 Score: 115.161 bits (287), Expect = 3.158e-26 Identity = 88/299 (29.43%), Postives = 145/299 (48.49%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFE-----INNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQL-------------YNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQIVKLMTYPEEMV 10438 V D Y ++L G ++ + EKST +E+ KF + + G+ R E + ++ + H NI+ + D +VLI E + G L +++ Q E + I Q++ V+YLH ++ H D+KPENI++ K I +KL F A ED +++ T F APE++ EP+ +DMWSIG++T++ L G F GD ++E+ S A FIRK L+ +T +RLT ++L H W I P + A + + +V L + ++ V Sbjct: 19 VEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTD-VVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSG--ASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPW-ITPVDTQQAMVRR--ESVVNLENFKKQYV 311 HSP 2 Score: 63.1586 bits (152), Expect = 3.672e-9 Identity = 39/139 (28.06%), Postives = 67/139 (48.20%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRY-----ESDIWSLGILSFLLLATQLPAIEDACSDS 12070 E V GG L L + SE + I+Q+L + +LH+ + H +++P I++ + IKLI G E E K +IF PE+ I Y E+D+WS+G+++++LL+ P + D ++ Sbjct: 104 ELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDF------GLAHEIEDGVEFK-NIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQET 235
BLAST of Serine/threonine kinase vs. Ensembl Mouse
Match: Dapk2 (death-associated protein kinase 2 [Source:MGI Symbol;Acc:MGI:1341297]) HSP 1 Score: 115.546 bits (288), Expect = 1.106e-25 Identity = 83/274 (30.29%), Postives = 133/274 (48.54%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFE-----INNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQL-------------YNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPG 10363 V D Y ++L G ++ + EKST +E+ KF + + G+ R E + ++ + H NI+ + D +VLI E + G L +++ Q E + I Q++ V+YLH ++ H D+KPENI++ K I +KL F A ED +++ T F APE++ EP+ +DMWSIG++T++ L G F GD ++E+ S A FIRK L+ +T +RLT ++L H W G Sbjct: 19 VEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTD-VVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSG--ASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITSKG 289 HSP 2 Score: 63.1586 bits (152), Expect = 5.224e-9 Identity = 39/139 (28.06%), Postives = 67/139 (48.20%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRY-----ESDIWSLGILSFLLLATQLPAIEDACSDS 12070 E V GG L L + SE + I+Q+L + +LH+ + H +++P I++ + IKLI G E E K +IF PE+ I Y E+D+WS+G+++++LL+ P + D ++ Sbjct: 104 ELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDF------GLAHEIEDGVEFK-NIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQET 235
BLAST of Serine/threonine kinase vs. Ensembl Mouse
Match: Obscn (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF [Source:MGI Symbol;Acc:MGI:2681862]) HSP 1 Score: 118.627 bits (296), Expect = 2.101e-25 Identity = 106/459 (23.09%), Postives = 200/459 (43.57%), Query Frame = 2 Query: 9104 KITWTFNNAKVDVNDERYKIFSAETYGIY-FIIKNLEEDDFGEY-CALDE------------VQDPI---------QSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSV-QINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRS--EFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNA---VPKEDFGSRRHMGLTSP-FSAPELLKGEPIQFNSDMWSIGILTFLCL-----------HGHLKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIK 10357 +I W + + + RY++ + G+ +I+ ++D G Y C L +Q P + + AP++ + + + + + I+ PPP V W + ++ SS R +++ ++ TYSL+++ D G Y+ A NA G K L V + + Q+ ++ Y +++ +G + + V K ++ KF + + ++ E + + H + + D + L+LI E L + + + E++V++ I QL++ + YLH H + HLDIKP NI+M E +K+C F A P E S+ SP F +PE+++ P+ SD+W++G++++L L L EG ++ + +S A FI+ L R ++S L+H WF+K Sbjct: 6367 QIRW-YKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEGAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSAR--LSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELLVHGGDKLDAENQVYRRKLHSFYDVQEEIGRGVFGFVKRVQHKGNKMFCAAKFIPLRSKTRAQAYQERDILATLGHPLVTGLLDQFET-RKTLILILELCSSEELLDRLFKKGVVTEAEVKVYIQQLVEGLHYLHSHGILHLDIKPPNILMVHPAREDIKICDFGFAQKITPSEPQYSK----YGSPEFVSPEIIEQNPVSEGSDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPTAAHLSEDAKDFIKATLQRTPRARPSTSQCLAHPWFLK 6817 HSP 2 Score: 78.1814 bits (191), Expect = 3.675e-13 Identity = 56/216 (25.93%), Postives = 103/216 (47.69%), Query Frame = 2 Query: 9752 EFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNA--VPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSND----------AISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPG 10363 E++ ++ + H ++ ++ A P ++LVLI E G L + + + ES V+ + Q++ A YLH + HLD++ EN+++T +YN +LK+ NA + +E + + APELL+G+ +D+W+IG+ F+ L G + EG + + +S A F++ L + R +S L W + G Sbjct: 7780 EYEALKRLHHPHLAQLHAAYLSP-RHLVLILELCSGPELLPSLAERESYSESDVKDYLWQMLSATQYLHAQHILHLDLRSENMMVT-EYN-LLKVIDLGNAQSLDQEKVPAPENFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSGEYPESSEGTRDLQKGLRKGLIRLSRCYAGLSGGAVAFLQSSLCAQPWGRPCASTCLQCGWLTEEG 7992 HSP 3 Score: 65.855 bits (159), Expect = 1.621e-9 Identity = 52/197 (26.40%), Postives = 88/197 (44.67%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWF 12259 E LL L + V +E V I+QL+ + +LHS+ ++H +I+P IL+ + DIK+ Q + + Q S + F +PE ++ SDIW++G++S+L L P +SD LL V + H S+ ++ F+ +L+++P R + LAH WF Sbjct: 6636 ELCSSEELLDRLFKKGVVTEAEVKVYIQQLVEGLHYLHSHGILHLDIKPPNILMVHPARE--DIKICDFGFAQKITPSEPQYS--KYGSPEFVSPEIIEQNPVSEGSDIWAMGVISYLSLTCSSP----FAGESD--------RATLLNVLEGRVSWSSPTAAH-LSEDAKDFIKATLQRTPRARPSTSQCLAHPWF 6815 HSP 4 Score: 65.855 bits (159), Expect = 2.032e-9 Identity = 169/871 (19.40%), Postives = 321/871 (36.85%), Query Frame = 2 Query: 3962 LEAKIISGNINSYKTPPQWFWNDEAVK-NINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSK-KDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYIC----QGFTNKELISECK--ITLNVVDNISD------TLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLE-VVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSG--VYKFEGMVDGKLLELVHFTVQVN-PIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESR------VPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV-----------TDSEPKESDSS--RIIVKPLCAPVLTAEYSKGADVILS 6463 L++ ++S + QW+ +D + + K +A+L I +D+G Y+ ++S V + I P++ + E +C E K +DI+W + L D I+ + L L++ SV+ D+GT +C + + L+ + K + L +D++S TLQC+V + V W +G +E+ D + L + + + G+Y C + +K+ S + +L+V + K +E+ EG + E V+S W+ +G F++ + + LT A ++D+G V+ G+ L + V + P++ TT + L CE L+ ++WL++ + + DL E G +V + S + E T + + K + + C E+ N +E +L VE + T+ S V + L + + L + ++ TD+ Y+ I ++ R Q + + K+ ++ + L+D ++ E + KF + + WF + + + + I Y LT+ K G + D R S LR ++E+ +F++ L D+ + E++ L C + WTKDG+TL R ++ E L+IT +D GRY C +G ++ +++ V D E E ++ R ++ + APV E+ G DV+ S Sbjct: 2639 LQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQ----------DAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSF---HEISHE--GCLHTLVLKSVRQADTGT-VCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEV-----------------------SDPEARVVWRKDG--VELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVG------ITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVMLSCE------------------LSRAGTSVRWLKDG-----KAIRKSQKYDLLSE--------GTRAVLVVRKASLKDSGEYTCETEASKSTAKL------CVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQA-------------RTQARLLVHGQKV-RVIEDLEDTAVQ-EGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGTVYFEAG--------DQRTSAALR--VTEK-------PSIFSRPLTDVTVTEGEDLTLVCETTT-VDSSVRWTKDGKTLRPSA---RCQLSHEGCQAQLLITATTPQDGGRYKCE----IGGASSSSIVRVHALPVRFRESLKDVEVPEGKAATLRCVLSSVAAPV---EWRHGDDVLKS 3382 HSP 5 Score: 61.2326 bits (147), Expect = 4.801e-8 Identity = 74/315 (23.49%), Postives = 127/315 (40.32%), Query Frame = 2 Query: 11159 NWKTIGYSV-DNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRNIHSLKQALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQ---KSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNR--ITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFK------APEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSD 12067 +W T+ + D YL L R YI R +K G PYS S + ++ L S + + L+ + +M + R +S + Q K+SG A+ IV ++ ED +K H P L ++ + L R + E G LL L R YSE V + Q+L Q+LH+ +++H ++ ++++ +K+I L N Q + +QE + P FK APE ++DIW++G+ +F++L+ + P + D Sbjct: 7661 SWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPYS--------------SPSEQVLLGGPNHLASEEESSRGRPAQLLPSTKTFAFQMQIRRGRFSVVRQCREKASGRAL----------AAKIV--PYQPEDKTAVLREYEALKRLHHPHL-AQLHAAYLSPRHLVLILELCSGPELLPSLAERESYSESDVKDYLWQMLSATQYLHAQHILHLDLRSENMMVTEYNL----LKVIDLGNAQSL----DQEKVPA--PENFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSGEYPESSEGTRD 7938 HSP 6 Score: 58.5362 bits (140), Expect = 2.691e-7 Identity = 134/657 (20.40%), Postives = 234/657 (35.62%), Query Frame = 2 Query: 4394 LLIDSVKLEDSGTYICQGFTNKE----LISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSV---SWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDL--QFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQ------VNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGE----LLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEV-EESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCC 6304 L+I+ V+ ED TY C K + E IT+ V+ KD +E A EC ++ SV W +L+ ++ ++ +G + L + + G I S + +L V +I + +T+ +E G EL V+S + QW KDD S + F L L+ D+GVY+ + G TV+ + P+Q +E R+ CE L+ K I+W N P LY +S H G +V + + + V + ++ + + +++V+ E + L E P + VW KD L +D + + + L + D+ DAG+Y+ ++ V V + I K LK ++ E E+ FE + ES + A+W + + F + LT+ A G+ V +G + SL++R + TK L+D E++ L+C + + W KDG+ + +++ +L E L++ +A ++DSG Y C Sbjct: 2502 LVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITI-------------VRGLKDMTVME-----PAPAWFECETSIPSVRPPKWLLGKTVLQAGGNV--GLEQDGTVHRLTLHKTCSTMTGPVHFTI-----GKSRSSAQLVVSDIPV----VLTRPLEPKAGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQA---GSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCE------------------LSHKDEDIEWSLNGTP-------------LYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSDPEARV---VWRKDGVELGPSD-KYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHV-----GITKRLKTVEVL----------EGESCSFECVLSHESPSDPAVWTVGGKTVGGSG-HFHAVRQGRKYTLTVKDAALSDAGEVVFSV---LGLT---SKASLIIRERPVD-----------ITKPLEDQRTTLGEDVMLSCE-LSRAGTSVRWLKDGKAIRK---SQKYDLLSEGTRAVLVVRKASLKDSGEYTC 3054 HSP 7 Score: 57.7658 bits (138), Expect = 5.125e-7 Identity = 172/793 (21.69%), Postives = 288/793 (36.32%), Query Frame = 2 Query: 3995 SYKTPPQWFWNDEAVKN---INCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNP------IQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVL--DNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNY--------FALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMM-CDPKPKILWTKDGETLD--SKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCL 6307 S P +W E +++ + ++D + +L+I + DSG+Y CG+ +S+ + + E G TL + ++W+ + L R + + N + L I + +ED+G Y C +E S TLNV +F +D S E + TM L S V W E L + ++ +G + EL+I + + G Y C+ G T+ L V+ + + K E TEG + L ++ K+ +W K S+ G ++ ++ L + D+G Y V G+ +V+ P ++S T+ + L C+ +S + P+ W++G + LR+ GD L D +L I V E +G Y C+ EK+ T+ K +VV ++ + E L E VP ++ VW K L + D R Q L+LRD++ DAG YS + + V P+R + L+ QD+ +E T + E+ E ++ + C Y L + ++ G+YT D G +S RLS+ P F L+ E + RL C++ +P + W K+G L SK RR + E L+I E +D+G Y CL Sbjct: 3791 SKAAPVEWRKGSETLRDGDRYSLRQD--GAMCELQIRGLTIEDSGEYTCV--------CGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMS--KAAPVEWRKGSETLGDGG-----RYSLRQNGAVCELQIHDLAVEDTGEYSC--VCGQEKTSA---TLNVK-------ALPPRFIEDLRSQEATEG-TMATLRCQMSKAAPVEWRKGSETL--RDGGRYSLRQDGAVCELQIHDLDVEDAGQYSCVC----GQEKTSAV-LTVDALPPKFTEGLKKE-EATEGTMVTLRC--QMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYS---CVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQ-----MSKAAPV-------EWRKGS-KTLRD----GDRYSLRQDGAMCELQICDLAV-EDTGDYSCVCGQEKTSA-----TLSVKAPQVV-------FQQPLQNLQAEEGSMASLRCELSVPNAAM---VWSKGGLEL-QGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTAAPVR-----FLRELQA-------QDV---DEGATARLRCELSR----------EAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTC----DAGHTQSIARLSVRAPK-------------PKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCE-----LLIHGLEAKDTGEYACL 4459 HSP 8 Score: 57.3806 bits (137), Expect = 6.370e-7 Identity = 78/324 (24.07%), Postives = 129/324 (39.81%), Query Frame = 2 Query: 5429 ELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP--FCYNLILRDVKMTDAGMY-----SLKINESSV-DILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAEN-MEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRL---SLMLRSEIS---EQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 EL CT E E ++L+ K I S W KD K + E DP +I P C LIL ++ D+G Y S N S++ ILV+V P+ + K F E E + VE + + W+ + + N + L I AA ++ G Y ++ N +G R G L S LR+ EQ++ + AP ++D+++ + + + + P P + W K L S R+ + ++L++T+ D+G Y C+ N G +A ++V Sbjct: 6248 ELADCTAEL-----GETVKLACRVTGTPKPIVS--WYKDGKPV-EVDPHHILIEDPDGSC-TLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFV------------------EGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEGAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSA---RLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELLV 6541
BLAST of Serine/threonine kinase vs. UniProt/SwissProt
Match: sp|O01761|UNC89_CAEEL (Muscle M-line assembly protein unc-89 OS=Caenorhabditis elegans OX=6239 GN=unc-89 PE=1 SV=3) HSP 1 Score: 136.346 bits (342), Expect = 6.465e-30 Identity = 157/617 (25.45%), Postives = 269/617 (43.60%), Query Frame = 2 Query: 8714 ITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGI-------------GKPSMVIKKIRRSDN---LNSPTTEKA--MMLQEKHCLAVPMFC--------CLSQKAELKFTKLMEYKLDKITWTFNNAKVDVND--ERYKIFSAETYGIYFIIKNLEEDDFGEY-C-ALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTY--SLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPE-------KKSVQINIGDVNDRYYTMKK----LAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIY-----EKLQGLS-LAEYITQLSHWC----ESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHM--GL------TSP-FSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ--LYNEDS----NDAISN---SACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +TLSW P + +P Y T +E R + E+ WS+ + NI + + +L+ +YQ R+ +GI P V RR++ L P EKA M E++ A P F C + + I W F +D + + K+++ I +++ G+Y C A ++ D Q+ ++ + P + L N + + + + V++D +P PE+ W + W+ I S R +D G Y SL+I+ + D G YS A N G A + V+A + ++ V I V + Y +K A+G+ R V EK+T EF+ + I++ + + ++ H IV++ + D+ L L+ + GLS LA +++ E+ VR+ + QL+ A+ ++H+ R+ HLD++PE I++ ++ LKL DFG R + GL SP F +PE+++ P+ +DMWS G+LT++ L G + + D L N DS + + N A F++K L RLT ++L H W Sbjct: 6292 LTLSWIPTKRAPPRYPQVTYVIEIREL-----PEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAENIYGISDPSPASPPSRLMAPPQPVFD--RRTNKVIPLLDPYAEKALDMRYSEQYACA-PWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVGQYQCFAKNDYGDAQQNIMVDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQD---GPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTVTVEAEGDYNDVELPRRRVTIESRRVRELYEISEKDEKLAAEGAPFR---VKEKATGREFLAQLRPIDDALMRHVDIH--NSLDHPGIVQMHRVLR--DEKLALVVFDNANSTIDGLSSLAHPGVEIAEPKGVNRETCVRVFVRQLLLALKHMHDLRIAHLDLRPETILL---QDDKLKLA---------DFGQARRLLRGLITGEIKGSPEFVSPEIVRSYPLTLATDMWSTGVLTYVLLTGLSPFHGDNDNETLANVDSCQFDSSPLGNFSYDAGDFVKKLLTEIPVSRLTVDEALDHPWI 6878 HSP 2 Score: 98.2117 bits (243), Expect = 2.106e-18 Identity = 171/766 (22.32%), Postives = 303/766 (39.56%), Query Frame = 2 Query: 4283 GFSKKDIKWKVLEDDLKQDKILQE---KRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEM-KSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDD--IDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLK-LICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFI----------DLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDE-KLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INESSVDILV---KVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSC--DNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCI-----------------------APLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKI-LDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVT-DSEPKESDSSRIIVKPLCAPVLT 6427 G S D++W K DK + E + + + L++ D+G Y + +N +E V ++ + E ++IN+ T+ ++ SV W +G+ ++ S +++ ++ +G + + I++ G Y C N G + T V+N+ +E+ E L V + +W KDD I N + F+LT A D G+Y + G+ L +F + + I T +L+ L + E + D K +I V N ++W ++D P +DN I L I+ + E G+Y C TNE E + + V+ E++ +P+ + L E + + EL V RV K W KD + + + + + L+++D D G Y+ + N++ D V K+ KQT E K L I +PL++ F E +TV E +V + + I FF+N++ E + +Q D LTI A ++ G Y + N G ++ L + +++ E + + AP F + L+ + K+ L C++ +P+PKI WTK+G+ ++ ++ RV+ + TL D+G Y C N G TE IIVT + PK + ++P+ V+T Sbjct: 3213 GGSAPDVEW------FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKA-SNPAGTAESSAEAEVTQSLEKPTFVR---ELVTTEVKINETATLSVTVKGVPDP-SVEWLKDGQPVQTDSSHVIAKVEGSGSYS-ITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFT---QKLRPLEVREQETL--DLKVTVIGTPVPN-----VEWFKDDKPIN----IDNSHIFAKDEGSGHHTLTIKQAR-GEDVGVYTCKATNEAGEAKTTANMAVQ---EEIEAPLFVQGLKPYEVE----QGKPAELVV--RVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKPLFI----EPLKETFAV-EGDTVVLECKVNKE-SHPQIKFFKNDQ-PVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVE---MSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVT 3932 HSP 3 Score: 92.0485 bits (227), Expect = 1.593e-16 Identity = 131/611 (21.44%), Postives = 246/611 (40.26%), Query Frame = 2 Query: 10622 PNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILN-ATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSP-----YLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRN-----IHSLKQALIFNRKWMLTSRQSNHFNDL--------------HDLIKDIS--SDDI-------------RMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFV-GTVKEQESLTTHKPSIFKAPEYRY-ESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNT--NTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPL 12319 P+ + E +K+D + P A + + + T +FT L+D + + A C +S S ++W ++L + R+ +E + ++ ILN A D+G + C A ++S RL+ G+ P +P + ++ E+ ++W YL I YR++ R + W T+ +D+ ++++L Y R+ AQN +G S+++ + Q + I LK + N M + +N + D+ ++ +DD R +VIR+ + ++ + AV ++ EY R + E++ L +F L E + +R F ++ Y+E V +RQ+ + FLH + H ++ P I+ ++ +S+ +KL+ Q V G VK + T + +PE+ E+ +SD+W +G+++F LLA P + + ++ V N + L+PV S+ F +LKKSP R D L+H + DP + E S++ L Sbjct: 7498 PSATAIERIKADIEKVTPCATKKN-DDGTFAPIFTARLRDVYLRKNQPA-----IFECAVS--ASPAPKVTWDFQGKILESNDRVTIE--QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPEGPTYLEGI---TYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIVQTHGKGAPKLQIDVLKSEIRLNVVSM-PQKSTNQLGGISEESEEDSEARTANEDMKSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAISEYESLRDGQHENVQ---RLIAAFNNSNFLYLLSERLYEDVFSRFVFNDY---------------YTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMF--QSKRSWVVKLVDFGRAQKVSGAVKPVDFDTK-----WASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDREEEIKENVINVKCDPNLIPV--------------NASQECLSFATWALKKSPVRRMRTDEALSHKFLSSDPSMVRRRESIKYSASRL 8055 HSP 4 Score: 83.5741 bits (205), Expect = 5.210e-14 Identity = 180/816 (22.06%), Postives = 331/816 (40.56%), Query Frame = 2 Query: 4013 QWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICF--NPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNN--NLSFLLIDSVKLEDSGTY--ICQGFTNKELISECKITLNVV---DNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEIL---EMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFN-STKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLR--NDMPFGDPCVL---DNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGEL-----LSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVD-----ILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETL--DSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTD 6361 +W+ N + + N K + + + LEI + QL D+ YK+ + +A +T + L IA I K L+ + E G+ L V+ K+IKW K K + Q ++ N L+I +D+ Y + S C +T+ + I L+ QV + I + + IE + + +V W+ NG+ L K+ + I +N + E+ ++ G Y+ + N+ G S+ + ++ VE +I L + K+ ITEG V + + + +W K+ + N F K + L A D+ YK +LE + + ++ K++ + +++ ++ V++ + V +WLR N + G ++ D+ L I S + + +G Y V NE K S GE+ + +E + E + VE P + + W K+++ + + P Y L + ++ D Y + ++ ++ D L V+P ++ I L+D+ + EP+ V+ + +VE G K I W+ +E+ DA+ +F + F+LTIP++ + G Y + + ND G V S G + + ++ SE + ++PL KD E+ + + L C + +P P+++W KDG L D + R LD TL I A+ D G+Y N G T++ + VT+ Sbjct: 4431 KWYKNGKEIPNAKAKDNGDGSYS-LEIPNAQLDDTADYKVVVSNDAGDADSSAALT-VKLPGIA-IVKGLE----DAEVPKGKKAVLQVETNK-KPKEIKW------YKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQV--------VSIGSPIKLE--IETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDT--GDYKVEVANEAG-SANSSGKITVEP-KITFLKPL-KDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKI-------VLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPEDV-RWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKD-AGEYTVEVINESG--------------KAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK---WYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLK--------------IVDGLKDVDVE-EPQPVELKVKVE--GIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYS-GSVVHVKSAKSSEPTSGANFLSPL-----KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVA--LDG--TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTE 5163 HSP 5 Score: 74.3294 bits (181), Expect = 3.709e-11 Identity = 62/273 (22.71%), Postives = 127/273 (46.52%), Query Frame = 2 Query: 9584 KKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQ--IEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPEL-LKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSAC-------VFIRKCLLLKTG-------ERLTSSDSLSHEWF 10351 K ++Q+ D R+ KG +S + ++ +T+ K ++ I SE++ +++ H N+ + A + +L L+ E+L + ++ ++ E QV + + Q+ A+ +LH + HLD+ P NI+ K + ++KL F A ++ G+ + + + +++PE + P+ SDMW +G++TF L G E D+ E+ + + N C ++CL T R+ + ++LSH++ Sbjct: 7771 KSNLQLQTDDPTGRFQIGGLKFKGRFSVIRDAVDSTTEGHAHCAVKIRHPSSEAI--SEYESLRDGQHENVQRLIAAFNNSN-FLYLLSERLYEDVFSRFVFN-DYYTEEQVALTMRQVTSALHFLHFKGIAHLDVNPHNIMFQSKRSWVVKLVDFGRA--QKVSGAVKPVDFDTKWASPEFHIPETPVTVQSDMWGMGVVTFCLLAGFHPFTSEYDR--EEEIKENVINVKCDPNLIPVNASQECLSFATWALKKSPVRRMRTDEALSHKFL 8035 HSP 6 Score: 73.559 bits (179), Expect = 5.779e-11 Identity = 169/795 (21.26%), Postives = 299/795 (37.61%), Query Frame = 2 Query: 4082 QLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAP-IKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTY-ICQGFTNKELISECKIT------LNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSD--ILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTA-----RTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMP--FGDPCVLDNPFIDLY-IESPQVNEHS-GLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELS----VESRVPTKSIDSAVWLKDEK---------LLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY-SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNF--TLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 +L I L D+G+Y + + S K V P I + L+ NIE G+ V+V ++ +KW + ++K + L+ K+I K L I+ +L+D Y + + S +T L +VD + D +E Q V ++ +E + W+ NG+ L+ +D + +G+ + L I + +S G Y ++ N G + ++ + E S K+ E+ EG+ L L+ E + W KD + ++ I L A+ +D G Y+ + G TV Q + + + + + D K +V+V + +QW N +P F D LD+ Y + V E G KCI NE E V +F+ + L + D +I + +E V W KD K + N D I + PF + +D G+Y + +NE I + +E + P+I PL+D + N + ++ +V+ +W+ + + A++ IQ+ D L I + E+ G Y N G + + S + ++ +Q ++ P FTK L D+ ++ L C + DP P+I W ++G+ L N +++ P+ +L + E+ + D G Y C N G T+A V Sbjct: 4836 RLIIPSADLKDAGEYTVEV--INESGKAKSDAKGEVDEKPEIVRGLE----NIEIPEGDDDVFKVEVSAPVRQ-VKWYKNDQEIKPNSHLEAKKIGPKKYE----LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDV------------DVEEPQPVELKVKVEGIPK--VIKWYKNGQELKPDADGFKFEEKPESGEFS-LTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQP----SKPKFVIPLKTGAALPGDKKEF--NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDETV---CEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPF---------EESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTV-NGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINT----SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL----RNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHV 5577 HSP 7 Score: 70.4774 bits (171), Expect = 5.306e-10 Identity = 116/503 (23.06%), Postives = 200/503 (39.76%), Query Frame = 2 Query: 4919 WSKDDIDCSNN--GIFNSTKNKNCFNLTKLKAEITDSGVY------KFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDP----CVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEF-VEITVKFK-DEKVVSPILGELLSCTVEEVNTIEDEKIEL-SVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMY----SLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFE--NEEI--DAENMEFIQWSCDNYFALTIP-AAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIV 6355 W KDD+ + F S ++ F +T ++TD+G Y ++ ++ + P + + C++ ++I EV W + + WL +D P D L I Q ++ +G+Y + NE E E+ V+ D+ V+P T+E V E E++ SV + P I +W + K L+E++ I C L ++DV GM S ++ +S D +KVR P P KPL+D ++ + V FEV+ SG + F +E+ E +E + D ++ ++IP + +KH G+ + N+ G S RL++ EQ E AP F K ++D + + E + +P P++ W +G +D VKI + L I A+ +G C N +G T+A ++V Sbjct: 581 WYKDDVQLHEDERHTFYSDED-GFFAMTIDPVQVTDTGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKE----CKEGDVI-------DFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPDD-TGVYTVKIQNEFGSIESKAELFVQADPDKNHVAP----EFQATIEYVECDEGEEVRFKSVITGDPNPEI---IWFINGKPLSESEKVKFISEDGICI-LTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP------------PTFNKPLEDKTVQEKSTVV---FEVDVSGWPEPTLTFTLCGKELKNGEEGVEIV--GHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV-------EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPG--VKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVV 1034 HSP 8 Score: 69.707 bits (169), Expect = 8.477e-10 Identity = 64/235 (27.23%), Postives = 105/235 (44.68%), Query Frame = 2 Query: 5792 EPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDG--------RLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFT--LIITEAEVEDSGRYCCLGTNFLGYDTT--EAVIIVTDSEPKESDSS-RIIVKPLCAPVLTAEYSKGADVI 6457 E + +K E +V+ S + +W+ + + + I S D L IP+ G Y + N G + G R S RS +++ + AP + L++I I K++ RL C+ DPKP I W KDGE + R++++ E P+ L++ A +D+G Y C+ N G T + +I D +P++ DSS R P LT +K D + Sbjct: 5714 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRS--ADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERV---FPYGRLQLI-ESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSV 5942 HSP 9 Score: 69.3218 bits (168), Expect = 1.002e-9 Identity = 225/1066 (21.11%), Postives = 428/1066 (40.15%), Query Frame = 2 Query: 3260 FFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKP--IDSNIETC--PGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLL-IDSVKLEDSGTY-ICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNG-EILEMKSDILSDIKNNGKIA-ELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKD--DIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFE-GMVDGKLLEL-VHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVL------DNPFIDLYIESPQVNEHSGLYKCIVTNEK-SETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFC---YNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF---IRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGY-DTTEAVIIV 6355 FF L I+ E + K D WF + L K + + + S + G ++ + + + ++ + V+ E + G D + + G + L++ + P T+K W+ +E + + + + E++ K+ I + E S YR+V + +S E + ++ K KI F+ L ++ + ++LE +I G K W+ N + +K+ + D + +L I Q D G+Y + A++ G++ S A + + KP + + T GE+ T V V+G K +KW K K + + + K N + S+ L I + ++ED+ Y + + S +T+ + D+ D ++ ++ +++ + T ++ V W+ NG EI K+ K+NG + L+I N Y+ ++ N G++ ++ L V+ I + + ++ E+ +G + L+V + +K + +W K+ +I S+ S + N L A D+ YK DG + TV+ L E ++ ED ++S P+ + +E + ++W +N ++P + DN ++ L I S V E +G YK V NE S +ITV+ K + P+ + ++ E E E SVE+ + + W K+ + E P I++ Y L++++ DA Y + + ESS + VK + K I K L+ + K + +F I+ EPE V+ W + I A I+ D + L IP+A K G+YT++V N+ G +SD + E+ E+ P + L++IEI ++ + P ++ W K+ + + KI + + L I A+++D Y + +N G D++ A+ +V Sbjct: 4020 FFKELSAIQVKETETAKFECKVSGTKPDV----KWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQ-----GTKILLSVEVEGKP-KTVK---WYKGTETVTSSQTTKIVQVTESEYKLEIESA--EMSDTGAYRVVLSTDSFSVESSATV--TVTKAAEKISLPSFKKGL------ADQSVPKGTPLVLEVEI-EGKPKDVK----WYKNGDEIKDGKVE-DLGNGKYRLTIPDFQEKDVGEYSVTA----ANEAGEIE-----SKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKW------YKNGKEIPDAKT--KDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQ--VKWYKNGKEIPNAKA------KDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSS-AALTVKLPGIAIVKGL-EDAEVPKGKKAVLQVETN-KKPKEIKWYKNGKEITPSDKAQPGSDGD-NKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVK-------LPAKEPKIIKGLEDQ--VVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV-LEIPS-SVVEDTGDYKVEVANEAGSANSSGKITVEPKI-TFLKPLKDQSIT---------EGENAEFSVETNTKPRIVK---WYKNGQ---EIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGAKMVFEVKIQGEPEDVR--------------WLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDA------KGEVDEK--------PEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPK--KYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4963 HSP 10 Score: 68.9366 bits (167), Expect = 1.400e-9 Identity = 157/732 (21.45%), Postives = 287/732 (39.21%), Query Frame = 2 Query: 4394 LLIDSVKLEDSGTYICQGF-------TNKELISE--CKITLNVVD------------NISDTLQCQVKFEKDKYS-IEINQDVTM----RALIECT---STHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNS-------STARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTV----QVNP-----IQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVL-----DNPFIDLYIESPQVNEHSGLYKCIVTNEKS-ETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAI-WFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDG-ETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKP 6406 L I + K ED G Y C+ TN +L + K+ +V D + DT + + +E+ + T+ +A+++C + W G+ +EM + + ++ K++G + L N ++ G Y C EN+ G++ T ++ D L V + +T G LE + +W K+ + ++ + + LT A++ D Y+ E + G + V TV QV P + +I + K C+ +S +KP + +W ++ P + + D+ L IE + ++ G Y+ V+N+ V +TV V S L + + +VN + KI LSVE K++ W K + + + + + Y L + +M+D G Y + ++ ESS + V TK K + +P KK L D + P+ EVE G K + W+ +EI +E + + + LTIP EK G+Y++ AN+ G + S ++++ + EI ++ + + E N ++ P + W K+G E D+K + + +++L I A+VED+ Y + +N G + A + V K +D + VKP Sbjct: 3744 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLT-LTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAV-VTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECK-----VSGTKPDV-------------KWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQ-GNYRIEVSNDAGVANSKVPLTV------VPSETL--KIKKGLTDVNVTQGTKILLSVEVEGKPKTVK---WYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTV----------TKAAEK-ISLPSFKKGLADQSV---PKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGKVEDL---GNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTT--------------VKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD------NGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTV-----KLADDGKDKVKP 4400 HSP 11 Score: 66.2402 bits (160), Expect = 8.898e-9 Identity = 85/362 (23.48%), Postives = 148/362 (40.88%), Query Frame = 2 Query: 5333 YKCIVTNE-KSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP--FCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFI-QWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDE---FPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVI-IVTDSEPKE 6376 YK I TN + T +IT K V +P+ + L T V E+ K+E+ V P W KD+K ++E D + P + L+++ TDAG Y+ K + ESS + E+ ++L+ P + L ++ ET V+ W + + + ++ I + +++TI A + GKY + N G +++ +++ + P F +KL +E+ KE+ L+ +++ P+P + W KD D+ V ++ + +F+L I +A D G Y C N G T A I+ DS P E Sbjct: 3165 YKAIATNSIGTATSTSKITTK-----VEAPVFEQGLKKT--SVKEKEEIKMEVKVGGSAP-----DVEWFKDDKPVSE-DGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEA--------------EVTQSLEKPTFVRELVTTEVKIN-ETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVV-----------KNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKD----DTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPE 3483 HSP 12 Score: 59.6918 bits (143), Expect = 9.480e-7 Identity = 94/384 (24.48%), Postives = 157/384 (40.89%), Query Frame = 2 Query: 5282 FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSP--ILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNET-DPRLTIIMQPFCYNLILRDVKMTDAGMYSLKIN------ESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEI-DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVK 6403 F + I+ QV + +G Y C+ TNE + K EK +P + +L +E + I+ E VE P + VWL D++ L + D RL Q L +RD + D G+Y++KI ES ++ V+ P KN P+ + ++ + +E E V+F+ + + IWF + + ++E ++FI S D LTI G T Q +N +G DGRL + + P F K L+D + K + + P+P + +T G+ L + + D F ++ T + D G N G + A + V + E +ES S+ +K Sbjct: 603 FFAMTIDPVQVTD-TGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVID---FECEVEG-WPEPEL---VWLVDDQPLRPSHDFRLQYDGQ--TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPD----------KNHVAPEFQATIEYVEC-DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFI--SEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPP-----------APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIVAKAQNEHGTAESRARLTV-EQEEEESRSAPTFLK 950 HSP 13 Score: 58.5362 bits (140), Expect = 2.263e-6 Identity = 40/181 (22.10%), Postives = 79/181 (43.65%), Query Frame = 2 Query: 9044 CCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIY-FIIKNLEEDDFGEYCA-----LDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRV 9568 + +K E+K + + W F + K D +++ G++ ++K D G+Y A + ++ + + PT + L + ++E ++SV + P P V W ++ + + + VI + + G+YS+ I L D G+Y+ RA N G A+ + N V Sbjct: 3198 TSVKEKEEIKMEVKVGGSAPDVEW-FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAV 3377 HSP 14 Score: 56.9954 bits (136), Expect = 5.493e-6 Identity = 39/138 (28.26%), Postives = 64/138 (46.38%), Query Frame = 2 Query: 5957 CGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP 6370 GKYT V N G + L+++ E + AP F L+D + E + L C+++ +PKPK+ W D +T+ + + V+ ++ T IT +E+ G+Y C+ N G TEA + V P Sbjct: 2959 AGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK-----APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESIT--VESVEGVERVT--ITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAP 3087
BLAST of Serine/threonine kinase vs. UniProt/SwissProt
Match: sp|A8DYP0|OBSCN_DROME (Obscurin OS=Drosophila melanogaster OX=7227 GN=Unc-89 PE=1 SV=1) HSP 1 Score: 135.191 bits (339), Expect = 1.346e-29 Identity = 136/610 (22.30%), Postives = 257/610 (42.13%), Query Frame = 2 Query: 8705 EREITLSWSPP-RISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTT------------EKAMMLQEKHCLAVPMFCCLSQKAELKF-------------TKLM----EYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEED-DFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDA------------HPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFF----EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLA-EYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLC--GFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH-----------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +R + LSW+P ++P I + +++ P E W +T ++ DI +L+P +Y+ R+ FG+ PS + R+ + P T E + + + P L+Q + T+LM Y K+T+ F++ ++ + ++ FI K L+ D + E A +E + Q L ++ P L + +N I ++ P PEV W ++WK I S R I+ + Y L I I+ DGG YSI A N G + ++ HP +S Q+ D+Y +L +G+ +E+S+ + K E+ + +E + + +H+N++ +DA D+ + LI E G L + + + ++ E + I Q + + ++HE V H+ + ++++++ +I+K+ G S + + + + + G+ F +PE++ E + F+ DMW++G++T++ L GH L EG + ++ IS+ FI + LL ER+ +L H WF Sbjct: 2847 DRGLLLSWNPSVPLTPRYPITYQIEMMDLP-------EGDWRTLRTGVRSCACDIRNLEPFRDYRFRVRVENKFGVSDPSPYTQTYRQKLVPDPPKTYTYLPPGTDFRPETSPYFPKDFDIERPPHDGLAQAPQFLLREQDISYGVKDHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEARQRVRLEIAEHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKIS-SYDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQYIYKTYGRHPYVRSKQLRY---QDKYDIGDELGRGTQGITYHAVERSSGDNYAAKIMYGRPELRPFML--NELEMMNTFNHKNLIRPYDAYDT-DRSVTLIMELAAGGELVRDNLLRRDYYTERDIAHYIRQTLWGLEHMHEMGVGHMGLTIKDLLISVVGGDIIKVSDFGLSRKINRHNLSTLDY-GMPE-FVSPEVVNKEGVNFSHDMWTVGLITYVLLGGHNPFLGIDDRETLTKIREGRWDFKDEIWTHISDDGRDFISRLLLYSPEERMDVKTALKHPWF 3440 HSP 2 Score: 116.316 bits (290), Expect = 6.869e-24 Identity = 103/426 (24.18%), Postives = 192/426 (45.07%), Query Frame = 2 Query: 10808 LGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSR-NKIRNWKTIGYSVDNR-YLLENLDRTQQYIARIIAQNKYGYSPYSI--ATSVFQNKIRNIHSLK-----QALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMED-----ICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 +G + W+KN +LT+ RIK+ V + G A DVG+++ +AR +T R+V+ +P P+ + + E+LL+W DD + ++ + + W T+ ++D+ YLL +L Y R+ ++N+ G+S I + S IH K Q L N ++ + H D H + + + + + + YS +S+ + G +K + +V + ++ D + FD +++ P LF ++ I E + G ++L+ +R YSE V T++ QLL +Q+LH H NI+P ++++ + +S +KL+ + + V + + +T F+ PE + +SDIWSLG L++LLL+ P Sbjct: 3678 VGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEISANSGTEILLRWK---QPRDDGHSTVLCYSLQYKLSNCDAWTTVADNIDHEFYLLHDLQPNTNYQFRLASKNRIGWSEMGIPVSASTVGGDAPKIHITKAMKHLQQLTENGHQVVPEEERVH-TDYH--CEREPPNWVTDSSVSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVPIAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMA--SVRSIQVKLVDFGSAKKVNKLGMK--VTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP 4093 HSP 3 Score: 109.768 bits (273), Expect = 6.380e-22 Identity = 73/264 (27.65%), Postives = 119/264 (45.08%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDA---IAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSN------------DAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFI 10354 V+D+Y + ++A+G +S I+KST + K E+ + +EF + + H I +F A + +P + + EKLQG + Y + + E V ++ QL+ A+ YLH CHL+I+P+N++M + +KL F +A G + + F PE++ EPI SD+WS+G LT+L L G F G Y N ++ A FI +R + D L H W + Sbjct: 3893 VSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVP--IAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMASVRSIQVKLVDFGSAKKVNKLGMKVTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSP--FRGADEYETKQNISFVRYRFENLFKEVTPEATRFIMLLFKRHPTKRPYTEDCLEHRWLM 4152 HSP 4 Score: 95.9005 bits (237), Expect = 1.023e-17 Identity = 180/814 (22.11%), Postives = 305/814 (37.47%), Query Frame = 2 Query: 4073 NLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAP----IKKNLKPID----SNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQD----KILQEKRITQKFNNNLSF--LLIDSVKLEDSGTYICQGFTNKELISECKITLNVVD--NISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNS-VTKNIEITEGNELNLEVVSEIEKDLQ--------FQWSKD----DIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRN--DMPFGDPCVLDNPFIDLYIESPQVN------EHSGLYKCIVTNEKSET-EFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLK-INE-----SSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIA----PLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSE 6367 N +L+I +C +D+G Y I AS+ V+ V AP K N +P + E V + G K +K+ E ++ + +I+++K + L F L+I V+ D+GTY C+ TNK + C+ V+ N L Q+ +K + W NGE + + + L Q+ GIY C+ + GN S + EL+V+ I LN K + E E N + +LQ QW D +D + ++ +++ +L + D+GVY E + + G+ ++ V+ P ++K I + I S + + + +EV + Q +Q N D+ + + I +E V +G Y TN+ S+T E+ TVK K P++ + E I EK + + R+ W DE + TD + T+ Y L + DAG Y++K NE SS +L+K P+ K L++I + V+ V+ A W+ + EID + +F N F L + G YT ++ ND G ++ ++C + P + LK++E+ ++ L + +P+ KI W KDG + + + N+ L + A ED+G Y TNF+G T+ + V SE Sbjct: 1072 NSYRLDIKNCSETDAGTYTI--RAQSASETTTVSAQLAVGQAPGHDETKTNTEPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDK-------DYLGFYELVIADVQKTDAGTYSCKA-TNKHGEANCEAIATTVEDKNPFGALSGQILPAGEKPVFQ---------------------WKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCS-AELSVQGA-IQTLNREPEKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMY---EDEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPP----------KIKKITD---ITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSK------PVIVKNF-----ESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCAPEFTHK-----------------LKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYG------------------KLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVLTSE 1790 HSP 5 Score: 92.4337 bits (228), Expect = 1.131e-16 Identity = 110/405 (27.16%), Postives = 176/405 (43.46%), Query Frame = 2 Query: 5150 DNEIILSDSKPLIISVEVLNWKQGVIQWLRND---MPFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCY-NLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIF-IRNEPETVKFEFEVEESGAKKAIWFFENEEI--DAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTT 6337 DN + + +PL++ V +QWL++ P + NP + L I S Q N+ SG YK I++N E + V K E++ L + S TV + E ++L E++V W KD LL + P + I P LI+ + DAG+Y I +I + + + K++K +F LQD I P VK + +V + K WF EI DA ++ ++ + DN +L I G Y + N G S +L + +++ E E AP F L+D+ + + L+ + +P P+++W+KDG TL N R+ + + + L I AE DSG Y CL N LG D++ Sbjct: 2227 DNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPND-SGAYKLIISNPHGE-KVALCAVAVKPEEMQPKFLKPITSQTV-----VVGEPLKL--EAQVTGFPAPEVKWYKDGMLLRPS-PEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFV--------AELQDASSIEGFP--VKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVE-NPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKAD--ETATEE---APQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTP---NERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSS 2602 HSP 6 Score: 68.9366 bits (167), Expect = 1.560e-9 Identity = 99/386 (25.65%), Postives = 160/386 (41.45%), Query Frame = 2 Query: 3929 SLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTS--NLAQLEIAHCQLSDSGQYK-ICFNPLEASKCGKVTGLFLVSIAPIK---KNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFN--NNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIE---INQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLN-------SVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVY 5032 +L++ + E ++LE + + + QW + + VK K T+ L +LEI CQ +DSG YK I NP G+ L V++ P + K LKPI S GE + L V GF ++KW K +L+ N N L+ID+ + D+G Y C NK E + +V S + V +D SIE + D+ + + + WF NG ++ + ++ ++N + L I+ G+YE + +N +G S+ ++ +L V + S +++ EG EL L + WSKD + + N T + LT AE DSG Y Sbjct: 2229 ALDVLQGEPLVLECCVDGSPLPTV----QWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNP-----HGEKVALCAVAVKPEEMQPKFLKPITSQTVVV-GEPLKLEAQVTGFPAPEVKW------YKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCL-IANKGGEIEGVSKVEIVPKESKPVF--VAELQDASSIEGFPVKMDIKV-----VGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEG-STASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNY 2589 HSP 7 Score: 64.3142 bits (155), Expect = 3.428e-8 Identity = 201/958 (20.98%), Postives = 369/958 (38.52%), Query Frame = 2 Query: 3629 LNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFT---SNLAQLEIAHCQLSDSGQYKI-CFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVK--------FEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVT---KNIEITEGNELNLEVVSEIEK--DLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVD-GKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPF---------GDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFV-EITVKFKDEKVVSPILGELLSCTVEE-----------VNTIED---EKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKI----------NESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPET----VKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEF--PNFTLIITEAEVEDSGRYCCLGTNFLG 6325 L A + P+ K G + E V F +E + + +V +V E +G+ S + ++G++ QT E EK L++E + +I + + L+ K + P + +D V ++ + F L I + D+G Y I N L + + + LV AP K +K I ++I GE++ + ++VEGF + ++ D+ + ++ + + + + +KL +G Y + N + S+ C VK FE + E ++V M I+ ++W+ + +++ +D + ++G LKI G Y N+ G S+T+ T+L I C T KNI + EG+ N+E+V ++ +W D I+ F + N F L + G Y + M D GKL + TV P ++K ++ E+ + K + VEV + + I+W ++ D ++N ++ L + E +G Y+ TN ET ++ V + + + + L T EE V+ + E + L E A+W D K + D I + Y L ++ + + DAG Y + + E S+ + + R KPI Q + K++K+ + K + + +P +K V E+ K + ++ DAEN +Q++C L I A K G+Y ++V N G + + G + ++ + EIS L D + L + I + +PKPK+ WT+ E L C + +++ + + L+ + G+Y TN G Sbjct: 1231 LPAGEKPVFQWKRNGEEFDPEERFKVLFGEDE----DSLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSVQGAI--QTLNREPEK--PTLVIEHREANASIGGSAILELQCK-------GFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDTVDAGVYTIEAINELGQDE----SSINLVVKAPPK--IKKI-TDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKA-------------TNDLSQTSEYWSCTVKSKPVIVKNFESEYIHGE-KENVQMTVRIDAYP-EAKLTWYHDETEIKI-TDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHG-SATSSTQL-----LIKCAPEFTHKLKNITVAEGDS-NVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNCKP----------KVKRGLKNVEV--QEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLAR---TEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPIT-PDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYR-KPILTQGPGL-KDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVK----LKVDKKDAENG-LVQYTC----TLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEIS---------------GLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENL---CNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEG 2098 HSP 8 Score: 63.1586 bits (152), Expect = 8.258e-8 Identity = 122/575 (21.22%), Postives = 230/575 (40.00%), Query Frame = 2 Query: 4703 LKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCS-NNGIFNSTKNKNCFNLTKLKAEITDSGVYKFE-GMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDM---PFGDPCVLDNP--FIDLYIESPQVNEHSGLYKCIVTNEKSETEFV-EITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQP-FCYNLILRDVKMTDAGMYSLKIN--ESSVDILVK--VRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDN-YFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDS 6385 L I++ E+ G Y C+ N+ G + A +L + ++ + + +++ +G L LE + QW KD + + I ST L + DSG YK G+ + L V+ +Q LK I ++ +PL + +V + ++W ++ M P + +++P I L I++ Q + +G+YKC++ N+ E E V ++ + K+ K V + EL ++ ++IE +++ + +V W + + + I+ P +LI+ D+G+Y + E S K V PK T+E PQ L+D+ +E + + + + IW + + E + +CD + LTI A G YT +AN +G S + P+FT+K+ D + + N ++ + P P + W + + + + I ++ + LI+ E D G Y C+ +N G D T+ + + + K S S Sbjct: 2183 LDIKSFRENDVGAYTCVATNEIG-VTKAPFKLAMLSLAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKF------LKPITSQTVVV---GEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLD-AGVYKCLIANKGGEIEGVSKVEIVPKESKPV--FVAEL-----QDASSIEGFPVKMDI--KVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEA------PQFVSALRDVNA-DEGQELVLSAPFISNPMPEVIW--SKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLG-----------EDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPK---SEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDITQGRLDIVNEIKKHSRS 2714 HSP 9 Score: 57.7658 bits (138), Expect = 3.636e-6 Identity = 59/237 (24.89%), Postives = 104/237 (43.88%), Query Frame = 2 Query: 5711 RKQTKEIFKNLKIPQIKKPLQDIFIRNEP-ETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCD--NYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKD-GETLDSKCLNRRVKIL---DEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAV-IIVTDSEPKESDSSRII 6397 R Q +++ P + K L+ + + EP ET FE + ++ W +N+ ++ + I + N + L I E G YTI+ + +L++ E + P F LKD E++ R +++ DPKP++ + KD E L++ N R++I+ D + L+I + + D+G Y C TN G EA+ V D P + S +I+ Sbjct: 1004 RLQEDRPLRSVDKPVVVKMLKSVQV--EPGETAHFEIQFKDQPGL-VTWLKDNKPLEDRLADRITQTAAPMNSYRLDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNT---EPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILET---NDRIQIIRDKDYLGFYELVIADVQKTDAGTYSCKATNKHGEANCEAIATTVEDKNPFGALSGQIL 1231
BLAST of Serine/threonine kinase vs. UniProt/SwissProt
Match: sp|Q15772|SPEG_HUMAN (Striated muscle preferentially expressed protein kinase OS=Homo sapiens OX=9606 GN=SPEG PE=1 SV=4) HSP 1 Score: 134.035 bits (336), Expect = 3.190e-29 Identity = 133/603 (22.06%), Postives = 270/603 (44.78%), Query Frame = 2 Query: 8708 REITLSWSPPRISPDLYIPFTVDVECRPVNYSYS------DEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITW-TFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGEYCALDEVQDPIQ--SFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQI-NIGD--------VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFF--EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIM--TGKYNEILKLCGFSNA---VPKE----DFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYI 10393 R +TL+W+PPR ++D+ P + +Y+ + W+ T +++ L + + R++ T KPS + ++ ++ PT E+A + +K + ++ Q A + T + ++ W + A ++ Y++ + I + D G + Q S L ++AP + + + + E +V ++ +P P+++W ++ + SS+ + + E+ E SL++ DGG Y+ A+N G K L V H + ++++ +G+ ++D Y +++ +G++S + ++E+S+ +EF KF + R E + + + H ++ +A + LV++ E L L E I + CES++R + Q+++ + YLH+ V HLD+KPEN+++ + +++C F NA P E +G T F APE++ P+ +D+W +G++ FLCL G E D+ + E + ++S A F+ K +L++ R T+ ++L H WF + D++ Sbjct: 1297 RMVTLTWNPPR---------SLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEH--GPTLEEAPAMLDKPDI---VYVVEGQPASVTVT--FNHVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENE---CSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV--HSAQTAMEVEGVGEDEDHRGRRLSDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHDCVLYFHEAFER-RRGLVIVTE-LCTEELLERIARKPTVCESEIRAYMRQVLEGIHYLHQSHVLHLDVKPENLLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQYG-------TPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIK-VLVQDRLRPTAEETLEHPWFKTQAKGAEVSTDHL 1868 HSP 2 Score: 115.546 bits (288), Expect = 1.019e-23 Identity = 79/270 (29.26%), Postives = 124/270 (45.93%), Query Frame = 2 Query: 9599 INIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSR--RHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH---------------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 + G Y +++ A+G + + E +T F+ K G R E++ ++ + H I+ + +A P +YLVLI E L ++ + E V + QL+Q + YLH H V HLDIKP+N+++ + LK+ F +A P R H T F APE++KGEPI +D+W G+LT++ L G + F+ QLY S SA +F+RK L + R + D L+H W Sbjct: 2957 LRQGPPQKPYTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERIMSLHEAYITP-RYLVLIAESCGNRELLCGLSDRFRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLLA--PDNALKIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAFQLYPN-----TSQSATLFLRKVLSVHPWSRPSLQDCLAHPWL 3218
BLAST of Serine/threonine kinase vs. UniProt/SwissProt
Match: sp|Q696W0|SPEG_DANRE (Striated muscle preferentially expressed protein kinase OS=Danio rerio OX=7955 GN=speg PE=2 SV=1) HSP 1 Score: 128.257 bits (321), Expect = 1.595e-27 Identity = 136/607 (22.41%), Postives = 259/607 (42.67%), Query Frame = 2 Query: 8708 REITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEG------WSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFI-----------IKNLEEDDFGE--YCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPE----------KKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEI--NNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAV---PKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF--IKPGNNLNAAL 10384 R I LSW P+ +D P + Y ++ W+ +++ + L + Y R++ T + KPS PT ++ + ++ P+ K ++ + +E + IT T N+ + +R + G + I ++ D G+ + A ++ + + L+ + P + + + + E +V +D +P P+++W ++ + SS+ T + +D+E SL++ D G Y+ A+N G K L V + ++ + + D Y K++ +G++S + V K+ Q F KF + E + + H++IV DA + +V+I +L L E IT+ + ES+V+ II QL++ + YLH++ + HLD+KPENI+M + + +++C F NA+ P E+ + G+ F APE++ PI ++D+W +G++T+LCL G E D+ + E + A FI K +L+ R +++ L H WF + G ++N L Sbjct: 949 RMILLSWKKPK---------NLDPSIDPASLMYVVQQQVLGSTQWTTIASSLTDTSYTVTSLSKGVCYSFRVLSTTGKTLSKPSQ-------------PTDLVQLVDRGEYFRKAPVII---DKPDIVYA--VENQPVTITITINHVQATCTWKRRGVVLVNKLGALEMTTPDDDQHALHIAKVKSTDVGQLIFMANNQYGSDLGTLQLVIAVPPIFETIMEDLDVCVGETCHFAVVVDGKPDPDILWYKDGVLLAESSHLTFVYDDRE---CSLVVLNAQPEDVGVYTCTAKNLAGSVSCKAELTVHTAQNVEEEEEQMEDEATILRRMRMLTDYYDIHKEIGRGAFSYVKRVKHKNDQ-SFAAKFISVRAKKKTCALRELALLAELDHKSIVRFHDAFE--KRRVVIILTELCHEELLERITKRTTILESEVQSIIRQLLEGIEYLHQNDIIHLDLKPENILMADQKTDQIRICDFGNALKVKPNEELYCK--YGIPE-FIAPEIVNQSPISKSTDIWPVGVITYLCLTGVSPFAGENDRDTLLNIRNYNVAFEESMFKDLCREAKGFIIK-VLVSNKLRPDATECLLHPWFKSLTKGKSINTTL 1518 HSP 2 Score: 92.8189 bits (229), Expect = 9.076e-17 Identity = 71/257 (27.63%), Postives = 124/257 (48.25%), Query Frame = 2 Query: 9626 YYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR--SEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAV---PKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDA----------ISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 Y + + A+G + + E +T FI K + E++ ++++ I+ + +A P +YLVLI E G + + + + E V I Q++Q + YLH ++ HLDIKP+NI++T ++K+ F +A P R++G T + APE+LKG+ + +D+WS+G+L+++ L G + QL ++A +S SA F++K L R T D L+H W Sbjct: 2682 YSFLDEKARGRFGVIRDCRENATGKMFIAKIIPYDQQTKQTIIKEYEILKSLRCERIMALHEAYITP-RYLVLITEYCSGKEILQNLIDRFCYSEDDVVGFIVQILQGLEYLHNCKILHLDIKPDNIMVTNL--NVIKIIDFGSAQRFNPLSLQQCSRYLG-TLEYMAPEMLKGDLVGPPADIWSLGVLSYIMLSGRHPFEDKDPQLTEAKIHEAKFDSTKLYPKVSQSASTFLKKILNSYPWCRPTIKDCLNHSWL 2934 HSP 3 Score: 79.7221 bits (195), Expect = 7.433e-13 Identity = 102/444 (22.97%), Postives = 177/444 (39.86%), Query Frame = 2 Query: 5756 IKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAE----NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPK-ESDSSRIIVKP--------------------LCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKPTIIFK-DATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSL-SLEPGVSYMFRVIAFNDFGISEPSQ--SLISRIDR 7000 I +P+QD+ ++ ET E + S A W + I M+F C F +A E G YT C S + L+ + ++ PLFT+KL+ +E + + + +C++ P P++ WT + L + + IL+ + +L+IT E G Y + N G + A + V + P + SR+ P P+ E +G + +L Y+ K + STN +K+ + + + S C S + +CV ++ G + + + S PPD P +I + +SW K KNL P +MY ++ + + W +++ L D Y++ SL GV Y FRV++ +S+PSQ L+ +DR Sbjct: 620 ITRPMQDVKVKAG-ETALLECFIAGSQAVDVDWLANGKLIQPALFDCKMQFDGHRCRLLFK----SAHENDSGCYT--------CKLSTAKEELI----CTANLLVIPSKEPLFTRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPL---VESDNIHILNVNGHHSLLITHVNKESEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSRLEKMPSIPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYH--NGKKIESTNDRKMTQYRDVHSLVIQSVCH--DHSGVYKCVISNKVGKAACYAHLYVAV---SLPEPPDGPPVIESVTGRMILLSWK--KPKNLDPSIDPASLMYVVQQQVLGSTQWTTIASSLTDTSYTVTSLSKGVCYSFRVLSTTGKTLSKPSQPTDLVQLVDR 1034 HSP 4 Score: 69.3218 bits (168), Expect = 1.055e-9 Identity = 86/384 (22.40%), Postives = 154/384 (40.10%), Query Frame = 2 Query: 5534 WLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRN-------EPETVKFEFEVEESGAKKAIWFF-ENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLM-LRSEISEQM-----MESCC-------------IAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSV----ATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSS 6592 WL + KL+ + L+ + D+G Y+ K++ + +++ NL + K+PL F R E + +F+ +V + W E ++++N+ + + + + +L I ++ G YT N G S L + R IS M M S P F K L D+E++ + L CR+ P PKI W +G+ ++S + + D +L+I + SG Y C+ +N +G A + V S P+ D +I E G ++LSW + D +++Y ++ Q+ L ST W I +LT+T+Y+++S Sbjct: 651 WLANGKLIQPALFDCKMQFDGHRCRLLFKSAHENDSGCYTCKLSTAKEELICTA--------------NLLVIPSKEPL---FTRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDNIHIL--NVNGHHSLLITHVNKESEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSRLEKMPSIPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIESTNDRKMTQYRDV---HSLVIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPEPPDGPPVI-----------ESVTGRMILLSWKKPKNLDPSIDPASLMYVVQ-QQVLGSTQWTTIASSLTDTSYTVTS 1000 HSP 5 Score: 64.3142 bits (155), Expect = 3.780e-8 Identity = 78/317 (24.61%), Postives = 130/317 (41.01%), Query Frame = 2 Query: 11417 SSDDIRMNVIREHYSTLSQKSSG-FAVLKLKNTNVNFPEYIV----------QRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPLVDFVN 12334 S +R V ++ YS L +K+ G F V++ N +I Q K +I + C RI H + + E+ G +L L+ R YSE VV I Q+L +++LH+ ++H +I+P I++ TN + IK+I + Q + Q+ + APE + +DIWSLG+LS+++L+ + P ED K+ + F + KL + S+S+ F+ L P R L HSW + T ++T L +F+ Sbjct: 2669 SETTLRQGVPQKPYSFLDEKARGRFGVIRDCRENATGKMFIAKIIPYDQQTKQTIIKEYEILKSLR-CERIMALHEAYITPRYL-------VLITEYCSGKEILQNLIDRFCYSEDDVVGFIVQILQGLEYLHNCKILHLDIKPDNIMV---TNLNV-IKIIDFGSAQRFNPLSLQQCSRYLGTLEYMAPEMLKGDLVGPPADIWSLGVLSYIMLSGRHP-FED-----------KDPQLTEAKIHEAKFDSTKL--YPKVSQSASTFLKKILNSYPWCRPTIKDCLNHSWLHDSYLKKLRRQTLTFTTTRLKEFMG 2959 HSP 6 Score: 62.7734 bits (151), Expect = 1.008e-7 Identity = 58/219 (26.48%), Postives = 93/219 (42.47%), Query Frame = 2 Query: 11615 ILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVK---EQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFK 12262 I+ E+C L RIT R+ E V +IIRQLL I++LH N+++H +++P IL++ D K + C F +K +E + F APE +S +DIW +G++++L L P + +D D ++N N + SM + ++ F+ L S R +A L H WFK Sbjct: 1324 IILTELCHEELLERIT---------------KRTTILESEVQSIIRQLLEGIEYLHQNDIIHLDLKPENILMA-------DQKTDQIRICDFGNALKVKPNEELYCKYGIPEFIAPEIVNQSPISKSTDIWPVGVITYLCLTGVSPFAGE--NDRDTLLNIRNYNVAF-----------EESMFKDLCREAKGFIIKVL-VSNKLRPDATECLLHPWFK 1506
BLAST of Serine/threonine kinase vs. UniProt/SwissProt
Match: sp|Q9UIK4|DAPK2_HUMAN (Death-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=DAPK2 PE=1 SV=1) HSP 1 Score: 119.013 bits (297), Expect = 9.931e-27 Identity = 85/281 (30.25%), Postives = 138/281 (49.11%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFE-----INNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQL-------------YNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAAL 10384 V D Y ++L G ++ + EKST +E+ KF + + G+ R E + ++ + H N++ + D +VLI E + G L +++ Q E + I Q++ V+YLH ++ H D+KPENI++ K I +KL F A ED +++ T F APE++ EP+ +DMWSIG++T++ L G F GD ++E+ S A FIRK L+ +T +RLT ++L H W I P +N A + Sbjct: 19 VEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTD-VVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSG--ASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPW-ITPVDNQQAMV 295 HSP 2 Score: 63.5438 bits (153), Expect = 2.023e-8 Identity = 39/139 (28.06%), Postives = 67/139 (48.20%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRY-----ESDIWSLGILSFLLLATQLPAIEDACSDS 12070 E V GG L L + SE + I+Q+L + +LH+ + H +++P I++ + IKLI G E E K +IF PE+ I Y E+D+WS+G+++++LL+ P + D ++ Sbjct: 104 ELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDF------GLAHEIEDGVEFK-NIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQET 235
BLAST of Serine/threonine kinase vs. TrEMBL
Match: G7Y5N7 (Striated muscle preferentially expressed protein kinase OS=Clonorchis sinensis OX=79923 GN=CLF_101401 PE=4 SV=1) HSP 1 Score: 580.096 bits (1494), Expect = 7.598e-162 Identity = 518/2018 (25.67%), Postives = 889/2018 (44.05%), Query Frame = 2 Query: 5390 KFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSID----SAVWLKDEKLLNETDPRLTIIMQP--FCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPK--PIRKQTKE-IFKNLKIPQIKKPLQDIFI----RNEPETVK---FEFEV-------EESGAKKAIWFFENEEI-DAE------------NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLM-LRSEISE-QMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP-----------------KESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNI-IEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNL----------TPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHL-----------KGQP---CLKWRAATVPEFCDSCVSGILPDYKVEYRNGRLSPWKIYQENIMQNE------TYLTQKIIDDAQ----------------EFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSPSVEKVKTIIKYDQLKQAEIESI---------------------------SKDGLSLKWSQWV------------PDQINKYIIQR-----------KNSFSQDWEQIH---STIFGENCFVEMILSENFSRQLRILSLDDNKT--ELHDGYNILYIPSKDECIPTIPENLQV-----NDLT------------NYHEIFWSESKSIEIVDS------PITYSLQSKVNNQF-----WFTITEKLDKCFYTNTRIDKYGVTG-YRV--LARNSIGSSPFSMEVFTKSLINILSNEQIIKSLRYFVINPREIEIKWHLCESIFD------------------SGIT--TEDLSFQIEKKTVKEGSDWVP----ISNIVERNSILISITFEDENLF-RIQPFYRDEKLSASRIFRMYVSKDLLVPDMSFTRPNLVIDSVTSCAIEWPEPELQSGFSPDGIEICVPSVLLVDLQYEIQFVVVDPIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTIDDT--VIPGSNGEREITLSWSPPRISP--DLYIPFTVDVECRPV--------------NYSYS-------DEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKI-----RRSDNLNSP--TTEKAMMLQEKHC--LAVPMFCCLSQKAELKFTKLMEYKLD---KITWTFNNAKVDVND-------ERYKIFSAETYGIYFI-IKNLEEDDFGEYC--ALDEVQDPIQSFILIKSDAPTILNC-LPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVI----TEDKEQG-----TYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINN-MG--IGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIM----------------------------------TGKY-----NEILKLCGFSNAVPKEDFGSRRHMGLTSP------FSAPELL---------KGEP---IQFNSDMWSIGILTFLCLHG-------H---------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQI 10405 + KD SP E L CT E +EL +R PT +D WL D K ++ + + P +L++ ++ AG YS++ ++++ + P P+ +K +F+ L I +K+P + R +P + FE E+ E AK N EI D E ++ W DN ALTIP G Y ++V + + L + R++IS ++ + + PLFTK+L+D E+ + +R R+M +P I+W +G + + R+K+ ++ N +L I A ED GRYCC+ TN LG TE V+ V D++ KE S+ P AP + +++ L W + + + + I + K WK I+ L ET S++ P E LR V +E+G S + IP RA P +P KP I F++A V I W + + +P +G++ Y++E+++ +S W+ V+ +L + Y+ L PG S RV+A N FG S P+ ++ +D L P+ +PPW+ L + QP + W+ A +PEFC SCV G+ P Y++E+R GR W+ +++ E T L + DDA+ E R+ C NK+G++GPT+ RL A+ + FR + K TI+ D ++ ++I + + +G+ L W ++ P+ N+Y I++ N+ DW+ + I+GE+ F+ + + R+L+L++ +T DGYN + IP E +P+ P +L V ND T N H + S E+V++ P+ + + + W + E R + G+ YR+ + R GSS S + T L + L E I+ +RY ++ P EI+++W L ++ D SG +E +SF +E + G DW P I + ++L + + ++ RI ++ SR R+ V D + PD +F +P + +++V I W EP++Q +S + + P L + Y +Q + QW+ + L+E + W P+P Q Y R++ NQFG+G+PS+ V++ PQ++IPD SFIR +I+ ++ GS L W PR P T +V+ R V ++S S DE W V +TN+K+ R+ + LDP + LRIV VTD+G G PS ++K+ +R +++ T +A + ++ + + EL+ + L + D + +W+ N +++ + RY+ + ++T + + + N+ E DFG Y A++ + FI+ K+DAP L +P ++ LH +F + +DA P + W R+ K++ S+RT I + KE SL + +CI D G Y++ AEN G + +RV+ P KS + D+ YY +++L KG S +++I+K T E++GK + +++ +G G EF+C+ + H N+V++ DAI + D LVL+ E+L G +L + + ++W ES ++ Q+++AV +LH + HLD++PEN++ T ++ + ++KL GFS+A P + + + P +SAPE+L EP + +DMWS+G+LT++ L G H L NF D D+IS++A F+R L + G R T+++ L H W N+ ++Y ++++ Sbjct: 1842 RSKDVPATSPFEFEKLRCTDLSAPITEGSNLELV--ARFPTFGLDYDENDFQWLVDGKAVSSEGSLVRVDTDPNQGHVSLVIPTIQPEHAGTYSIRFSDNAQKRIQDNAPANSPMGDLSKALVFQPLAI--LKRPQTSQAMSYSERWQPSNYRPSAFERELPPSTSIKEGEHAKLEARLGRNHEIFDHEWLVNGKPILPEFTSDYTIWRADNLLALTIPRMRRDLAGIYELRVFGEQDIYTTSTDLIVEPSRAKISSYKLTPADGLKPLFTKRLQDYEVDVGDCVRFTARVMAEPPAVIVWKHNGNIVTG---DHRIKLFNDDANPSLTIRHARPEDRGRYCCIATNALGRVDTEGVLQVHDTDRYVPLGDEFDAGGSLAGRKEIGGSKRTALPRTAPEVALVSMSVSNIDLRWKPIQSDEGITYIVELSKDGG---KWWKPIITGLRETHASIAEELASPLEPVQLRVVGENEFGTGPASTPPVRIPARACIPTMPQVKPDIEFEEAASVLIKWPKATASIMEHTLLTEHVISPSAMLGQVWYAVEVREGAQSEWRRVATNLKNQFYTYHLRPGASTAIRVVAANRFGESTPTPIGLAHLDPNTLAPNLDFNPPWVSLSRPVSDDGSTYEMQPLAVTVYWKPAYMPEFCSSCVRGLEPMYRLEWRRGRSGMWQALADDLTDPEAGFRLPTDLVLALQDDAKRMKDSRSLVALNSQAIELRLFCWNKYGESGPTKPCRLVASQL----FRG-QLYKNSTIVDKDSMQLSQITDVLQELDQLPVMSANDRCSRLLTRISSLSTTEGIGLSWEKFTLTGLPKTSGDQPPEPHNRYRIEKYIAKPSSTLDSPNTNQADWKVASLDAAVIYGED-FILDTRPDKEEQIYRLLALNETETCSMWVDGYNRIRIPPLSELVPSAPTDLTVQCVPVNDSTISAENHITWKPANQHPLLVELPPSSELVEARELATPPLDLRYRIEARSTLSELSPWRQVAEVYGGATSAVDRKAEPGLALIYRITPINRFGEGSSVTSPPIRTPILYSAL--EGCIEDVRYVILGPTEIQLRWRLGDAAIDALKHDQPTTWGRKRSLCRSGSVDYSERVSFMVEVRGGYAG-DWSPAVEQIQGDLNAKALLQDCHYLEHDISCRIVALIDGQRSVPSRPIRLNVRADAMTPDYTFVKPKVHVETVEEYVISWDEPDVQEIYSSHTLGLTTPQTLQRGMNYAVQV-------------QRESKPQWETIATQLKEPHYTWAQPNPLQAYHVRVLPANQFGTGIPSRSVRVEPQVVIPDLSFIRPSIEAPADILAGSTAPE---LVWQLPRTYSLEKTLTPVTYEVQVRGVANASRLALGPVPHADHSTSRQSAADDDETVWRVLETNVKRTRLPLGRLDPEQEFWLRIVAVTDYGRGAPSQSVRKLVDLAAKRQQRMSASIVTIHEATPVSPTFVDPKGTVLYAPVGGRLELR-SNLQTTQPDADIRFSWSLNGRPIEIPESVQQNRLSRYQSYVSKTCDVAVLQVHNVTESDFGVYVCKAVNIRGSTTKEFIVKKADAPVFLEVPVPVMTVKLHCSFELPCWVDAVPTATLYWTRDSKRVVESHRTKIGSRLSRTKEDAQCFTINASLSVDRCIYQDAGLYTLVAENIAGRVQTSCLIRVEESPIPKSPTLRWTDIGLHYYVLRRLEKGDVSELRLLIDKQTNQEYVGKLYFLDDPVGRVAGAREFECLSRLCHSNVVQLHDAI-VSDNVLVLVMERLTGPNLLKAMLHCNNWSESATASVVRQVLEAVQHLHSEGIVHLDLQPENLLFARNVTAETWDGQTSYTDLFKALSPLVSDTMGLRETDRHKMSVLSSLIKLVGFSSAEPLVNKSNAGPVYCYPPQRFRPEYSAPEVLIAASQSASTDAEPPNLVGPAADMWSVGVLTYVLLTGWCPFFDVHANEPLREQILSANFSMDL----SEFDSISDNAKQFVRDLLQINPGSRPTAAECLQHPWLSTLKNSGGQDVEYRLERL 3818 HSP 2 Score: 103.219 bits (256), Expect = 1.747e-17 Identity = 72/242 (29.75%), Postives = 120/242 (49.59%), Query Frame = 2 Query: 11618 LFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSN--NVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKL------SMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPL 12319 L + S+G +++ ++PGG L VL++R+ Y+EF+++ +QLL +++L+S HG I P IL +RR++ DI L G F G+++E +P F APE SD+WS+G L++LL+ P + +++ + T P H P + LH FSK ++KFV+N L+ P RG+ D+WL WF + + Q ++ TP+ Sbjct: 4402 LTNDAVKPSIGVSVSY--WIPGGQLFDVLVSRTEYTEFSIMRWTQQLLMALRWLYSKLFGRPHGAIIPRHILAARRSSTLPDIVLTG-----FGGSIEE----INGRPE-FTAPEVSQGEPISVFSDLWSIGALNYLLMTGNCP--DAKLAETSYKVLTETTADEEKPKLTGHQGDPHIPHYIDFKKLHMFSKPAKKFVYNCLQLVPKKRGHIDFWLESRWFDISTENV-----QRLTRTPI 4624 HSP 3 Score: 93.5893 bits (231), Expect = 1.418e-14 Identity = 73/253 (28.85%), Postives = 112/253 (44.27%), Query Frame = 2 Query: 10721 FTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISI----------------------------SWYKNQELLTDDSRIKLEVIKGGFLSCTI--LNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAID---DVIYRIDIRTIDSRNKIRNWKTIGYSVDNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRNIHSLKQALIFN-RKWMLTSRQS 11377 F PL+D F S + +CQL+ P I +WY LL+D ++L GG+L + LN ++ + +C+ R + + +T ARL++ D P P + + + E L+ W+P S +D D+IYR+D + + N W T+G++VD R+L NL Y R+ A N G+ YSIA+S F + L N R+WMLT RQS Sbjct: 3998 FASPLRDAYFNIHSGEAR----FSCQLAGFAHLPPGIHGHREAIAELYPTDVVNAQTGHSSATVAAWYLGGCLLSDGPGVQLGTGPGGWLWLYLSELNVDQSGT-VVKCVVRNRAGKAKTQARLLIADPPKPPGRPGMAEVHPTEALITWAP--SDVDVGGDLIYRVDAK-FAANNGPAAWHTLGFTVDCRFLAMNLQPGLCYRMRVSAGNSCGWGNYSIASSEFYTPTDRSSEVISLLNKNDREWMLTWRQS 4242
BLAST of Serine/threonine kinase vs. TrEMBL
Match: A0A5J4NRQ3 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0005864 PE=4 SV=1) HSP 1 Score: 572.778 bits (1475), Expect = 1.140e-159 Identity = 487/1863 (26.14%), Postives = 810/1863 (43.48%), Query Frame = 2 Query: 5606 NLILRDVKMTDAGMYSLKINESS---------VDILVKVRPKPIRKQTKEIFKNLKIPQIK---KPLQDIFIRN----EPETVKFEFE----------------VEESGAKKAI-----WFFENEEIDAE-NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSL---MLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVT-------------DSEPK--------ESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCK------------NLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHLKGQP---CLK-----------WRAATVPEFCDSCVSGILPDYKVEYRNGRLSPWKIYQENIMQNETY------LTQKIIDDAQ----------------EFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSPSVEK-----------------------VKTIIKYDQLKQAEIESISK-DGLSLKWSQW-----------VPDQIN-KYIIQRK---NSFSQD--------WEQIHST---IFGENCFVEMILS-ENFSRQLRILSLDDNKTELHDGYNILYIPSKDECIPTIPENLQVNDL-----------------TNYHEIFWSESKSIEIVDSPITYSLQSK-VNNQF--WFTITEKLDKCFYTNTRIDKYGVTG----YRVLARNSIGSSP--FSMEVFTKSLINILSNEQIIKSLRYFVINPREIEIKWHLCESIFD----------------SGITTEDLS----FQIEKKTVKEGSDWVPISNIVERNSILISITFEDENLF------RIQPFYRDEKLSASRIFRMYVSKDLLVPDMSFTRPNLVIDSVTSCAIEWPEPELQSGFSPDGIEICVPSVLLVDLQYEIQFVVVDPIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTIDDTV-IPGSNGEREITLSWSPPRISP--DLYIPFTVDVECRPVNYSY-------------SDEEG---------WSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPT--TEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLD-KITWTFNNAKVDVNDERY--KIFSAETY----GIYFIIK--NLEEDDFGEYC--ALDEVQDPIQSFILIKSDAPTILNC-LPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVI-------TEDKEQGT------YSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINN---MGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENI-------------------------------IMTGKYNE--------ILKLCGFSNA------VPKEDFGSRRH---MGLTSPFSAPELL----------------KGEPIQFNSDMWSIGILTFLCLHG 10198 +L L++V+ +G YSL E + +D L + P+ + + K L P++ KP D + + EP + FE +E + AKK W F + I E ++ W +N LTIP A + G Y ++V D G + +L + LRS + ++ + + P+FTK+L D + + +RL R+M +P I+W +G + + RVK+ ++ N +L I + D GRY C+ TN LG TTE+++ V DSE + E + S P AP L + +V LSW + D I Y +E + W+ I+ + +T ++SS P +S L R +A +++G S I IP RA P +P KP + F++A V I W + + P G + Y++E+++ +S W+ V+ DL Y L PGVS RV+A N FG S P+ + +D L P DPPW+ + Q C K W+ A +PE+C +CVSG+ P Y++E+R GR W+ +++ E L ++DD + E RV C NKFG++GPT+ RL A+ + + S++ V T +Y +L+ I SIS DG+ L W ++ +P + + +Y I+++ + +Q+ W+ ++ I+GENC +++ E +L LS D+ + D YN + IP E P+ P L + + + H +F + + I Y ++++ V + W + E Y +DK G YR+ N G P S + T L + L E ++ LRY ++ P ++++W L +S D SG ++ DL+ F +E ++ G DW P+ ++ + + +D + R+ F ++ + SR ++ + D L PD S +P++VI SV W EP +Q +S + + P VL D +Y +Q + N W+ L E+LEE ++W P+P Y FR++ NQFGSG+PS+ V++ PQ++IPD SF+R TI+ V I + E L W PR PFT +V+ R V +S S+ G W V +TN+K+ R+ ++ LDP + LR+V VTD+G G PS ++K+ + SPT K ++ + + CCL + M Y + + +W N +++N+ Y ++ +Y Y +++ +L + DFG Y A++ + F++ K+DAP L +P ++ LH F + +DA PP + W R+ K++ S+RT I +E KE SL + +CI D G Y++ AEN G + +R++ P +V I D+ YY ++ L KG S +++I+K E++ K F +++ G EF+C+ + H N+V++ DA+ + D L+LI E+L G + E + S W E + +I Q+ QA+ +LH HRV H +I+P ++ + TG + +KL GFS A P ++ H + FSAPELL + +D+WS+G+LT++ L G Sbjct: 1565 SLSLKEVRPDQSGTYSLGFTEDAASAIAQSAALDTLTSLPPRDV------LLKKLAFPKLTIKPKPEHDGLVGSGPQYEPTRAAYAFERDLPSTVSIKEGERVNLEATVAKKCKILMHEWLFNGKPIIPEFTPDYTVWRTNNSLMLTIPRARPELNGTYELRVYEDTGVYCTKTQLDVEQTRLRSS-NYKLTPADGLKPIFTKRLHDHTMDVGDCLRLAVRVMAEPPAVIVWKHNGAVVTG---DHRVKLFNDDANASLTIRQVRPSDRGRYSCIATNALGRVTTESILQVNGVEQFAALGDEDDDSEDQVRRSADGTERNRSAYTALPRTAPELRLDSVDTMNVALSWKPLMQPD---ITYIVELSRD-GGKWWRPILNGVADTFVNISSVLASPLDSLLFRVLAENKFGIGPASQSIRIPARACIPTMPAIKPKVEFEEAAAVLIRWPKATTGLSTEPCMVVDDYTINPAAKFGHVWYAVEVREGAQSEWRRVAADLTGLSYLYHLRPGVSSAIRVVAINQFGESNPTPITLVHLDPSTLAPAMDFDPPWVAVTHQAYDGCPKPGQQKTGITVYWKPAHMPEYCTACVSGLEPMYRIEWRRGRTGMWQALADDVTDPEAGFRLPNNLVMAVLDDVKRTSDSQNTIAINNQTVELRVFCWNKFGESGPTKPCRLVASQLFRGQTYKNSIKNMDKHQDSILRMEDCFNEWDQFPVVTTDDRYLRLR-TYINSISPVDGIELSWEKFTQTCLPNGAEEIPIETHGRYRIEQRLPVDRSTQERIGRSRYRWKVCNTDTALIYGENCVLDVRPGKEEQVYRLLALSETDSCSVWVDAYNTIRIPPLTELCPSAPMELTIRTVPVTGCTVSAENHLSWRSSTSHPVFSQGHDKQDTMSPIIRYRVEARSVQSDLAPWRQVCETFADDTYA---VDKKAEAGLQLIYRITPVNEFGEGPALISSPIRTPPLYSSL--EGCVEDLRYTILGPSGLQLRWRLGDSAIDILEFERSASNHTGPKRSGSSSLDLADRVNFTVEVRSGYAG-DWSPLVEQIQ-GDLAAKVKLDDVHYMKNDLSCRVVAFIDGQRSAPSRPVQLNIKADSLTPDFSLVKPHVVISSVDEYLFSWDEPHVQETYSAHILALTTPQVLQKDTRYAVQI-------------QREGNSTWETLAENLEEPHWSWSQPNPLWSYHFRVLPSNQFGSGVPSRAVRIEPQVVIPDLSFMRPTIESPVDILAATTAPE--LVWQLPRAYSLEKTLTPFTYEVQVRGVGHSRSALASVPDRGRSTSNSRGTTTEEEETMWRVLETNVKRTRLTLSRLDPEKEFWLRVVAVTDYGRGAPSQPVRKLVDLAAI-SPTFIEPKGQVIYAPIGGHLELKCCL---------QPMRYDPEIRFSWFLNEKPININESHYPHRMSRHHSYVSKNSDYAVLQVDHLTDTDFGIYVCKAVNIRGTATKEFVVKKADAPVFLEVPVPLLTVRLHTGFELPCWVDAVPPASLYWTRDSKRVVESHRTKIGCTVMSQSESKESTVSQMTTNASLSVDRCIYQDAGLYTLVAENIAGRVQTSCLVRIEDAPTPNTVSIRWADIGKHYYVLRCLKKGPISELRLLIDKRNNQEYMAKLFPLDDPVSRVCGAREFECLSRVCHSNVVQLVDAV-VSDNVLILIMERLTGPDILESMLYCSSWSEGAAKAVIRQVTQAIEHLHSHRVVHFNIQPNSLRFVQHLTPDSWDTQTAYTDLFRTLSPLVSDTMGTGLTDRHKMSVLSSSIKLLGFSVAEPLVTDQPATNWLQSDHPPPQRIQPEFSAPELLFVQSTATDGSRTKTEASAAEVGTPADIWSLGVLTYVLLAG 3379
BLAST of Serine/threonine kinase vs. TrEMBL
Match: A0A4S2LRW1 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005285 PE=4 SV=1) HSP 1 Score: 569.311 bits (1466), Expect = 1.876e-158 Identity = 513/2019 (25.41%), Postives = 883/2019 (43.73%), Query Frame = 2 Query: 5390 KFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSID----SAVWLKDEKLLNETDP--RLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPK--PIRKQTKE-IFKNLKI------------PQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEI-DAE------------NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLM-LRSEISEQMMESC-CIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP-----------------KESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNI-IEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNL----------TPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHLKG-----------QP---CLKWRAATVPEFCDSCVSGILPDYKVEYRNGRLSPWKIYQENIMQNE------TYLTQKIIDDAQ----------------EFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSPSVEKVKTIIKYDQLKQAEIESI---------------------------SKDGLSLKWSQWV------------PDQINKYIIQR-----------KNSFSQDWEQIH---STIFGENCFVEMILSENFSRQLRILSLDDNKT--ELHDGYNILYIPSKDECIPTIPENLQ-----VNDLT------------NYHEIFWSESKSIEIVDS------PITYSLQSKVNNQF-----WFTITEKLDKCFYTNTRIDKYGVTG----YRV--LARNSIGSSPFSMEVFTKSLINILSNEQIIKSLRYFVINPREIEIKWHLCESIFD------------------SGIT--TEDLSFQIEKKTVKEGSDWVP----ISNIVERNSILISITFEDENLF-RIQPFYRDEKLSASRIFRMYVSKDLLVPDMSFTRPNLVIDSVTSCAIEWPEPELQSGFSPDGIEICVPSVLLVDLQYEIQFVVVDPIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTID--DTVIPGSNGEREITLSWSPPRISP--DLYIPFTVDVECR-----------PVNYSY----------SDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKI-----RRSDNLNSPTTEKAMMLQEKHCLAVP----MFCCLSQKAELKFTKLMEYKLD---KITWTFNNAKVDVND-------ERYKIFSAETYGIYFI-IKNLEEDDFGEYC--ALDEVQDPIQSFILIKSDAPTILNC-LPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVI----TEDKEQG-----TYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINN-MG--IGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIM----------------------------------TGKY-----NEILKLCGFSNAVPKEDFGSRRHMGLTSP------FSAPELL---------KGEP---IQFNSDMWSIGILTFLCLHG-------H---------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQI 10405 + +D SP E L CT +++T E L + +R PT +D WL D ++ R+ +L++ +++ AG YS++ ++++ + P P+ +K +F L I P +P F R P + + E AK N EI D E ++ W DN ALTIP G Y ++V + + L + R++IS + S + PLFTK+L+D E+ + +R R+M +P I+W +G + + R+K+ ++ N +L I A ED GRYCC+ TN LG TE V+ V D++ KE S+ P AP + +++ L W + + + + I + K WK I+ L ET S+S P E +R V +E+G S + IP RA P +P KP I F++A V I W + + +P +G++ Y++E+++ +S W+ V+ +L + Y+ L PG S RV+A N FG S P+ ++ +D L P+ +PPW+ L QP + W+ A +PEFC SCV G+ P Y++E+R GR W+ +++ E T L + DDA+ E R+ C NK+G++GPT+ RL A+ + FR + K T++ D ++ ++I + + +G+ L W ++ P+ +Y I++ N+ DW+ + I+GE+ F+ + + R+L+L++ +T DGYN + IPS E +P+ P +L VND T N H + S S E+V++ P+ + + + W + E T + +D+ G YR+ + R GSS S + T L + L E I+ +R ++ P EI+++W L ++ D SG +E +SF +E + G DW P I + ++L + + ++ R+ ++ + SR R+ V D + PD +F +P + +++V I W EP++Q +S + + P L + Y +Q + QW+ + L+E + W P+P Q Y R++ NQFG+G+PS+ V++ PQ++IPD SFIR +I+ ++ GS L W PR P T +V+ R PV ++ DE W V +TN+K+ R+ + LDP + LRIV VTD+G G PS ++K+ +R +++ A P ++ + + EL+ + L + D + +W+ N+ +++ + RY+ + ++T + + + NL E DFG Y A++ + FI+ K+DAP L +P ++ LH +F + +DA P + W R+ K++ S+RT I + KE SL + +CI D G Y++ AEN G + +RV+ P K + DV YY +++L KG S +++I+K T E++GK + +++ +G G EF+C+ + H N+V++ DAI + D LVL+ E+L G +L + + ++W ES ++ Q+++A+ +LH V HLD++PEN++ T ++ + ++KL GFS+A P + + + P +SAPE+L EP + +DMWS+G+LT++ L G H L +F D D+IS++A F+R L + G R T+++ L H W N+ ++Y ++++ Sbjct: 2556 RSEDTPATSPFGFEKLRCT--DLSTPITEGSNLELVARFPTFGLDYDENDFQWLADGNAVSNKGSLVRVDTDETQGHVSLVIPNIQPEHAGTYSIRFSDNAQKRIKDNAPTTPPMGDLSKALVFPPLVILKRAMSCSERWQPSKYRP--SAFDRELPPSTSIK---EGEHAKLEARLGRNHEIFDHEWLVNGKPILPEFTSDYTIWRADNLLALTIPRMRRDLAGIYELRVFGEQDVYTTSTDLIVEPSRAKISSYKLTSADGLKPLFTKRLQDYEVDVGDCVRFTARVMAEPPAVIVWKHNGSIVTG---DHRIKLFNDDANPSLTIRHARPEDRGRYCCIATNALGRVDTEGVLQVHDTDRYVPLGNEFDAGGSVAGRKEIGGSKRTALPRTAPEVALVSMSVSNIDLRWKPIQSDEGVTYIVELSKDGG---KWWKPIITGLRETHASVSEELASPLEPVQIRVVGENEFGTGPASAPPVRIPARACIPTMPQVKPDIEFEEAASVLIKWPKATASIMEHTLLTEHVISPSAMLGQVWYAVEVREGAQSEWRRVATNLKNQFYTYHLRPGASTAIRVVAANRFGESSPTPIGLTHLDPNSLAPNLDFNPPWVSLSRPVSDDGSTYEIQPLGVTVYWKPAYMPEFCSSCVRGLEPMYRLEWRRGRSGMWQALADDLTDPEAGFRLPTDLVLALQDDAKRMKDSRSLVTLNSQAIELRLFCWNKYGESGPTKPCRLVASEL----FRG-QLYKNSTVMDKDSMQLSQITDVLQELDQLPVMSANDRCSRLLTRISSLSTTEGIGLSWEKFTLTGLPKASGDQPPEPHGRYRIEKYIARPTSPMDSPNTNQTDWKVASLDAAVIYGED-FILDTRPDKEEQIYRLLALNETETCSMWVDGYNRIRIPSLSELVPSAPTDLTIQCVPVNDSTISAENHINWKPANQHPLLVELSPSSELVEAKELANPPLDLRYRIEARSTLSELSPWRQVAEVYGG---TTSVVDRKAEPGLALIYRITPINRFGEGSSVTSPPIRTPILYSAL--EGCIEDVRSVILGPTEIQLRWRLGDAAIDALKHDQPNTWGRKRSLCRSGSVDYSERVSFTVEVRGGYAG-DWSPAVEQIQGDLNAKALLQDCHYLEHDISCRVVALIDGQRSAPSRPIRLNVRADAMTPDYTFVKPKVHVETVEEYVISWDEPDVQEIYSSHTLGLTTPQTLQRGMNYAVQV-------------QRESKPQWETIATQLKEPHYTWAQPNPLQAYHVRVLPANQFGTGIPSRSVRVEPQVVIPDLSFIRPSIEAPADILAGSTAPE---LVWQLPRAYSLEKTLTPVTYEVQVRGVANASRLALGPVPHAVHSASRQSAADDDETVWRVLETNVKRTRLPLGRLDPEQEFWLRIVAVTDYGRGAPSQSVRKLVDLAAKRQQRMSASIVTIHEATPVSPTFADPKGTVLYAPVGGRLELR-SNLQTIQPDADIRFSWSLNDRPIEIPETAQQNRLSRYQSYVSKTSDVAVLQVHNLTESDFGVYICKAVNIRGSTTKEFIVKKADAPVFLEVPVPVMTIKLHCSFELPCWVDAVPTATLYWTRDSKRVGESHRTKIGSRMSRTKEDAQCFTINASLSVDRCIYQDAGLYTLVAENIAGRVQTSCLIRVEESPIPKYPTLRWTDVGLHYYVLRRLEKGDISELRLLIDKQTNQEYVGKLYFLDDPIGRVAGAREFECLSRLCHSNVVQLHDAI-VSDNVLVLVMERLTGPNLLKAMLHCNNWSESATASVVRQVLEALQHLHCEGVVHLDLQPENLLFARNVTAETWDGQTSYTDLFKALSPLVSDTMGLRETDRHKMSVLSSLIKLVGFSSAEPLVNKSNADPVYCYPPQRFRPEYSAPEVLVAASQSASTDAEPPILVGPAADMWSVGVLTYVLLTGWCPFFDMHTSEPLREQILSASFTMDL----SEFDSISDNAKQFVRDLLQINPGSRPTATECLQHPWLSTLKNSDGQDVEYRLERL 4527 HSP 2 Score: 100.908 bits (250), Expect = 1.019e-16 Identity = 71/242 (29.34%), Postives = 118/242 (48.76%), Query Frame = 2 Query: 11618 LFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSN--NVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKL------SMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPL 12319 L + S+G +++ ++PGG L VL++R+ Y+EF+++ +QLL +++L+S HG I P IL +RR++ DI L G F G+ +E + S F APE SD+WS+G L++LL+ P + +++ + T P H P + LH FSK ++K V+N L+ P RG+ D+WL WF + + Q ++ TP+ Sbjct: 5111 LTNDAVKPSIGVSVSY--WIPGGQLFDVLVSRTEYTEFSIMRWTQQLLMALRWLYSKLFGRPHGAIIPRHILAARRSSTLPDIVLTG-----FGGSNEE-----INGRSEFTAPEVSQGETISVFSDLWSIGALNYLLMTGNCP--DAKLAETSYKVLAETTTDEEKPKLTGHQGDPHIPHYIDFKKLHMFSKPAKKLVYNCLQLLPKKRGHIDFWLESRWFDISTENV-----QRLTRTPI 5333 HSP 3 Score: 97.4413 bits (241), Expect = 1.215e-15 Identity = 135/525 (25.71%), Postives = 222/525 (42.29%), Query Frame = 2 Query: 725 KRNPRESFREDILQISNKNQESTMKRKYALADLIECDREYCATXXXXXXXXXXXXXTENEFGVEIDSLFEEVCKLIVE------------------LVEFHENLILPELSSCVMIP-------IRVANILKNQKLQFYRYSEFQSQWX--------XXXXXXXXXXXXXXFVKNVNTI-----EKSKFSVLSFNDLMLKVENKLPQYNLFLFDIIRYTGRIDGEVNDLQKAITVFQKIRRRNQEKVYLSKLIEKTN------INI-SNERFIRVTNQVMISETQIMSKSYENLQFIREEM--CSLILLKNYLLCV--SDLSQPTD-RKIMNLDYTKIYTKENYERQNELI-IW-SKMNKLEFRIFILYFPNKVSKLGWLRDLTKRLK---KKGIDEIFVSSTEYDIQYKQYLGKNQRLVATEMESIGLESASLENECSSISDQIEDLTSMADSITDVR--FESAILDMPS----------SMTSGSYKTAPETFKSTMDKASRPISGISQDSVSTLDGVRTPFSD 2098 KR+PRE FRE+++ ISNK QES MKR+YAL +LIE +REY L + D L FG + E + ++ +++F E +L EL++C M P IR A L++ + F Q L +L D S +N ++ +++ + +L + +L Y + L D+ RYT + L+ +TV + RR +E + I +T IN+ N+R + ++ T + + L+ I E LILL ++L + +LS D I+ LD +I E ++Q IW ++ + +I +Y + +S+ W+ D+ + L + G +E V S + L K + A ME S SLE+ D ++ + S+ D+ + ++D+ S S TS SY TA E ++ S +S +TLD VRTPFS+ Sbjct: 420 KRDPRELFREEVITISNKQQESKMKRRYALTELIETEREYVKALTPLLDAL-------TRFGTRVTLHLGEATEETIDIPKPLQQCIRNLRDKLKKIIDFTEKTLLDELAACTMNPPSAAECFIRNAAALEHYSIYLLHLDAFVKQLTLINGPDSDALFVLQDSSSPPRSPTENGDSTSALCNQRTSITYKYLLELFDLPKLRLLAYRVLLRDVARYTSQAGASTEQLEHGMTVIARTSRRTEETLMFWTKINQTTSECVEWINMYKNKRTGNLMPPALVRLTDLETNIRTGLRPISSETKKGRLILLPQHILFLQKQELSDTWDISWIIKLDGLRIGASELSDKQPPWFEIWNTEGSDPTKKIVRIYCADTLSQNAWMEDIRRALMNLLQCGDEETLVDSAVVSAHEEADLRKRLKF-AHVMELPAFRSDSLEDFFVDALDDLQKQQATFSSVDDIHNGQKPQVVDLVSMSTATSKKQDSSTSSSYHTA-EELSDHQTSCAKETSTTLYESYTTLDDVRTPFSE 935 HSP 4 Score: 94.7449 bits (234), Expect = 7.662e-15 Identity = 70/250 (28.00%), Postives = 109/250 (43.60%), Query Frame = 2 Query: 10721 FTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISI----------------------------SWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVG-IFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAID-DVIYRIDIRTIDSRNKIRNWKTIGYSVDNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKI-RNIHSLKQALIFNRKWMLTSRQS 11377 F PL+D F S + +CQL+ P I +WY LL+D ++L GG+L + G + +C+ R + + +T ARL++ D P P + + + E L+ W+P +D D+IYR+D + + N W T+G++VD R+L NL Y R+ A N G+ YSIA+S F R+ + +R+WMLT RQS Sbjct: 4707 FASPLRDAYFNIHSGEAR----FSCQLAGFAHLPPGIHGHREAIAELYPTDVVNAQTGHSSATVAAWYLGGCLLSDGPGVQLGTGPGGWLWLYLSELNVDQAGTVVKCVVRNRAGKAKTQARLLIADPPKPPGRPGMAEVHPTEALITWAPSDVDVDGDLIYRVDAK-FAANNGPAAWHTLGFTVDCRFLAMNLQPGLCYRMRVSAGNSCGWGNYSIASSEFYTPTDRSSEVISLLSKDDREWMLTWRQS 4951
BLAST of Serine/threonine kinase vs. TrEMBL
Match: A0A4S2LXN5 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005285 PE=4 SV=1) HSP 1 Score: 568.926 bits (1465), Expect = 2.222e-158 Identity = 513/2019 (25.41%), Postives = 883/2019 (43.73%), Query Frame = 2 Query: 5390 KFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSID----SAVWLKDEKLLNETDP--RLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPK--PIRKQTKE-IFKNLKI------------PQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEI-DAE------------NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLM-LRSEISEQMMESC-CIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP-----------------KESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNI-IEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNL----------TPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHLKG-----------QP---CLKWRAATVPEFCDSCVSGILPDYKVEYRNGRLSPWKIYQENIMQNE------TYLTQKIIDDAQ----------------EFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSPSVEKVKTIIKYDQLKQAEIESI---------------------------SKDGLSLKWSQWV------------PDQINKYIIQR-----------KNSFSQDWEQIH---STIFGENCFVEMILSENFSRQLRILSLDDNKT--ELHDGYNILYIPSKDECIPTIPENLQ-----VNDLT------------NYHEIFWSESKSIEIVDS------PITYSLQSKVNNQF-----WFTITEKLDKCFYTNTRIDKYGVTG----YRV--LARNSIGSSPFSMEVFTKSLINILSNEQIIKSLRYFVINPREIEIKWHLCESIFD------------------SGIT--TEDLSFQIEKKTVKEGSDWVP----ISNIVERNSILISITFEDENLF-RIQPFYRDEKLSASRIFRMYVSKDLLVPDMSFTRPNLVIDSVTSCAIEWPEPELQSGFSPDGIEICVPSVLLVDLQYEIQFVVVDPIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTID--DTVIPGSNGEREITLSWSPPRISP--DLYIPFTVDVECR-----------PVNYSY----------SDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKI-----RRSDNLNSPTTEKAMMLQEKHCLAVP----MFCCLSQKAELKFTKLMEYKLD---KITWTFNNAKVDVND-------ERYKIFSAETYGIYFI-IKNLEEDDFGEYC--ALDEVQDPIQSFILIKSDAPTILNC-LPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVI----TEDKEQG-----TYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINN-MG--IGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIM----------------------------------TGKY-----NEILKLCGFSNAVPKEDFGSRRHMGLTSP------FSAPELL---------KGEP---IQFNSDMWSIGILTFLCLHG-------H---------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQI 10405 + +D SP E L CT +++T E L + +R PT +D WL D ++ R+ +L++ +++ AG YS++ ++++ + P P+ +K +F L I P +P F R P + + E AK N EI D E ++ W DN ALTIP G Y ++V + + L + R++IS + S + PLFTK+L+D E+ + +R R+M +P I+W +G + + R+K+ ++ N +L I A ED GRYCC+ TN LG TE V+ V D++ KE S+ P AP + +++ L W + + + + I + K WK I+ L ET S+S P E +R V +E+G S + IP RA P +P KP I F++A V I W + + +P +G++ Y++E+++ +S W+ V+ +L + Y+ L PG S RV+A N FG S P+ ++ +D L P+ +PPW+ L QP + W+ A +PEFC SCV G+ P Y++E+R GR W+ +++ E T L + DDA+ E R+ C NK+G++GPT+ RL A+ + FR + K T++ D ++ ++I + + +G+ L W ++ P+ +Y I++ N+ DW+ + I+GE+ F+ + + R+L+L++ +T DGYN + IPS E +P+ P +L VND T N H + S S E+V++ P+ + + + W + E T + +D+ G YR+ + R GSS S + T L + L E I+ +R ++ P EI+++W L ++ D SG +E +SF +E + G DW P I + ++L + + ++ R+ ++ + SR R+ V D + PD +F +P + +++V I W EP++Q +S + + P L + Y +Q + QW+ + L+E + W P+P Q Y R++ NQFG+G+PS+ V++ PQ++IPD SFIR +I+ ++ GS L W PR P T +V+ R PV ++ DE W V +TN+K+ R+ + LDP + LRIV VTD+G G PS ++K+ +R +++ A P ++ + + EL+ + L + D + +W+ N+ +++ + RY+ + ++T + + + NL E DFG Y A++ + FI+ K+DAP L +P ++ LH +F + +DA P + W R+ K++ S+RT I + KE SL + +CI D G Y++ AEN G + +RV+ P K + DV YY +++L KG S +++I+K T E++GK + +++ +G G EF+C+ + H N+V++ DAI + D LVL+ E+L G +L + + ++W ES ++ Q+++A+ +LH V HLD++PEN++ T ++ + ++KL GFS+A P + + + P +SAPE+L EP + +DMWS+G+LT++ L G H L +F D D+IS++A F+R L + G R T+++ L H W N+ ++Y ++++ Sbjct: 2506 RSEDTPATSPFGFEKLRCT--DLSTPITEGSNLELVARFPTFGLDYDENDFQWLADGNAVSNKGSLVRVDTDETQGHVSLVIPNIQPEHAGTYSIRFSDNAQKRIKDNAPTTPPMGDLSKALVFPPLVILKRAMSCSERWQPSKYRP--SAFDRELPPSTSIK---EGEHAKLEARLGRNHEIFDHEWLVNGKPILPEFTSDYTIWRADNLLALTIPRMRRDLAGIYELRVFGEQDVYTTSTDLIVEPSRAKISSYKLTSADGLKPLFTKRLQDYEVDVGDCVRFTARVMAEPPAVIVWKHNGSIVTG---DHRIKLFNDDANPSLTIRHARPEDRGRYCCIATNALGRVDTEGVLQVHDTDRYVPLGNEFDAGGSVAGRKEIGGSKRTALPRTAPEVALVSMSVSNIDLRWKPIQSDEGVTYIVELSKDGG---KWWKPIITGLRETHASVSEELASPLEPVQIRVVGENEFGTGPASAPPVRIPARACIPTMPQVKPDIEFEEAASVLIKWPKATASIMEHTLLTEHVISPSAMLGQVWYAVEVREGAQSEWRRVATNLKNQFYTYHLRPGASTAIRVVAANRFGESSPTPIGLTHLDPNSLAPNLDFNPPWVSLSRPVSDDGSTYEIQPLGVTVYWKPAYMPEFCSSCVRGLEPMYRLEWRRGRSGMWQALADDLTDPEAGFRLPTDLVLALQDDAKRMKDSRSLVTLNSQAIELRLFCWNKYGESGPTKPCRLVASEL----FRG-QLYKNSTVMDKDSMQLSQITDVLQELDQLPVMSANDRCSRLLTRISSLSTTEGIGLSWEKFTLTGLPKASGDQPPEPHGRYRIEKYIARPTSPMDSPNTNQTDWKVASLDAAVIYGED-FILDTRPDKEEQIYRLLALNETETCSMWVDGYNRIRIPSLSELVPSAPTDLTIQCVPVNDSTISAENHINWKPANQHPLLVELSPSSELVEAKELANPPLDLRYRIEARSTLSELSPWRQVAEVYGG---TTSVVDRKAEPGLALIYRITPINRFGEGSSVTSPPIRTPILYSAL--EGCIEDVRSVILGPTEIQLRWRLGDAAIDALKHDQPNTWGRKRSLCRSGSVDYSERVSFTVEVRGGYAG-DWSPAVEQIQGDLNAKALLQDCHYLEHDISCRVVALIDGQRSAPSRPIRLNVRADAMTPDYTFVKPKVHVETVEEYVISWDEPDVQEIYSSHTLGLTTPQTLQRGMNYAVQV-------------QRESKPQWETIATQLKEPHYTWAQPNPLQAYHVRVLPANQFGTGIPSRSVRVEPQVVIPDLSFIRPSIEAPADILAGSTAPE---LVWQLPRAYSLEKTLTPVTYEVQVRGVANASRLALGPVPHAVHSASRQSAADDDETVWRVLETNVKRTRLPLGRLDPEQEFWLRIVAVTDYGRGAPSQSVRKLVDLAAKRQQRMSASIVTIHEATPVSPTFADPKGTVLYAPVGGRLELR-SNLQTIQPDADIRFSWSLNDRPIEIPETAQQNRLSRYQSYVSKTSDVAVLQVHNLTESDFGVYICKAVNIRGSTTKEFIVKKADAPVFLEVPVPVMTIKLHCSFELPCWVDAVPTATLYWTRDSKRVGESHRTKIGSRMSRTKEDAQCFTINASLSVDRCIYQDAGLYTLVAENIAGRVQTSCLIRVEESPIPKYPTLRWTDVGLHYYVLRRLEKGDISELRLLIDKQTNQEYVGKLYFLDDPIGRVAGAREFECLSRLCHSNVVQLHDAI-VSDNVLVLVMERLTGPNLLKAMLHCNNWSESATASVVRQVLEALQHLHCEGVVHLDLQPENLLFARNVTAETWDGQTSYTDLFKALSPLVSDTMGLRETDRHKMSVLSSLIKLVGFSSAEPLVNKSNADPVYCYPPQRFRPEYSAPEVLVAASQSASTDAEPPILVGPAADMWSVGVLTYVLLTGWCPFFDMHTSEPLREQILSASFTMDL----SEFDSISDNAKQFVRDLLQINPGSRPTATECLQHPWLSTLKNSDGQDVEYRLERL 4477 HSP 2 Score: 100.523 bits (249), Expect = 1.098e-16 Identity = 71/242 (29.34%), Postives = 118/242 (48.76%), Query Frame = 2 Query: 11618 LFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSN--NVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKL------SMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPL 12319 L + S+G +++ ++PGG L VL++R+ Y+EF+++ +QLL +++L+S HG I P IL +RR++ DI L G F G+ +E + S F APE SD+WS+G L++LL+ P + +++ + T P H P + LH FSK ++K V+N L+ P RG+ D+WL WF + + Q ++ TP+ Sbjct: 5071 LTNDAVKPSIGVSVSY--WIPGGQLFDVLVSRTEYTEFSIMRWTQQLLMALRWLYSKLFGRPHGAIIPRHILAARRSSTLPDIVLTG-----FGGSNEE-----INGRSEFTAPEVSQGETISVFSDLWSIGALNYLLMTGNCP--DAKLAETSYKVLAETTTDEEKPKLTGHQGDPHIPHYIDFKKLHMFSKPAKKLVYNCLQLLPKKRGHIDFWLESRWFDISTENV-----QRLTRTPI 5293 HSP 3 Score: 97.4413 bits (241), Expect = 1.204e-15 Identity = 135/525 (25.71%), Postives = 222/525 (42.29%), Query Frame = 2 Query: 725 KRNPRESFREDILQISNKNQESTMKRKYALADLIECDREYCATXXXXXXXXXXXXXTENEFGVEIDSLFEEVCKLIVE------------------LVEFHENLILPELSSCVMIP-------IRVANILKNQKLQFYRYSEFQSQWX--------XXXXXXXXXXXXXXFVKNVNTI-----EKSKFSVLSFNDLMLKVENKLPQYNLFLFDIIRYTGRIDGEVNDLQKAITVFQKIRRRNQEKVYLSKLIEKTN------INI-SNERFIRVTNQVMISETQIMSKSYENLQFIREEM--CSLILLKNYLLCV--SDLSQPTD-RKIMNLDYTKIYTKENYERQNELI-IW-SKMNKLEFRIFILYFPNKVSKLGWLRDLTKRLK---KKGIDEIFVSSTEYDIQYKQYLGKNQRLVATEMESIGLESASLENECSSISDQIEDLTSMADSITDVR--FESAILDMPS----------SMTSGSYKTAPETFKSTMDKASRPISGISQDSVSTLDGVRTPFSD 2098 KR+PRE FRE+++ ISNK QES MKR+YAL +LIE +REY L + D L FG + E + ++ +++F E +L EL++C M P IR A L++ + F Q L +L D S +N ++ +++ + +L + +L Y + L D+ RYT + L+ +TV + RR +E + I +T IN+ N+R + ++ T + + L+ I E LILL ++L + +LS D I+ LD +I E ++Q IW ++ + +I +Y + +S+ W+ D+ + L + G +E V S + L K + A ME S SLE+ D ++ + S+ D+ + ++D+ S S TS SY TA E ++ S +S +TLD VRTPFS+ Sbjct: 420 KRDPRELFREEVITISNKQQESKMKRRYALTELIETEREYVKALTPLLDAL-------TRFGTRVTLHLGEATEETIDIPKPLQQCIRNLRDKLKKIIDFTEKTLLDELAACTMNPPSAAECFIRNAAALEHYSIYLLHLDAFVKQLTLINGPDSDALFVLQDSSSPPRSPTENGDSTSALCNQRTSITYKYLLELFDLPKLRLLAYRVLLRDVARYTSQAGASTEQLEHGMTVIARTSRRTEETLMFWTKINQTTSECVEWINMYKNKRTGNLMPPALVRLTDLETNIRTGLRPISSETKKGRLILLPQHILFLQKQELSDTWDISWIIKLDGLRIGASELSDKQPPWFEIWNTEGSDPTKKIVRIYCADTLSQNAWMEDIRRALMNLLQCGDEETLVDSAVVSAHEEADLRKRLKF-AHVMELPAFRSDSLEDFFVDALDDLQKQQATFSSVDDIHNGQKPQVVDLVSMSTATSKKQDSSTSSSYHTA-EELSDHQTSCAKETSTTLYESYTTLDDVRTPFSE 935 HSP 4 Score: 91.2781 bits (225), Expect = 7.465e-14 Identity = 70/260 (26.92%), Postives = 111/260 (42.69%), Query Frame = 2 Query: 10721 FTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISI----------------------------SWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVG-IFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAID-DVIYRIDIRTIDSRNKIRNWKTIGYSVDNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVF-----------QNKIRNIHSLKQALIFNRKWMLTSRQS 11377 F PL+D F S + +CQL+ P I +WY LL+D ++L GG+L + G + +C+ R + + +T ARL++ D P P + + + E L+ W+P +D D+IYR+D + + N W T+G++VD R+L NL Y R+ A N G+ YSIA+S F ++ R+ + +R+WMLT RQS Sbjct: 4657 FASPLRDAYFNIHSGEAR----FSCQLAGFAHLPPGIHGHREAIAELYPTDVVNAQTGHSSATVAAWYLGGCLLSDGPGVQLGTGPGGWLWLYLSELNVDQAGTVVKCVVRNRAGKAKTQARLLIADPPKPPGRPGMAEVHPTEALITWAPSDVDVDGDLIYRVDAK-FAANNGPAAWHTLGFTVDCRFLAMNLQPGLCYRMRVSAGNSCGWGNYSIASSEFYTPTDHPSRFDSSEDRSSEVISLLSKDDREWMLTWRQS 4911
BLAST of Serine/threonine kinase vs. TrEMBL
Match: A0A4S2LYL9 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005285 PE=4 SV=1) HSP 1 Score: 568.926 bits (1465), Expect = 2.243e-158 Identity = 513/2019 (25.41%), Postives = 883/2019 (43.73%), Query Frame = 2 Query: 5390 KFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSID----SAVWLKDEKLLNETDP--RLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPK--PIRKQTKE-IFKNLKI------------PQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEI-DAE------------NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLM-LRSEISEQMMESC-CIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEP-----------------KESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNI-IEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNL----------TPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHLKG-----------QP---CLKWRAATVPEFCDSCVSGILPDYKVEYRNGRLSPWKIYQENIMQNE------TYLTQKIIDDAQ----------------EFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSPSVEKVKTIIKYDQLKQAEIESI---------------------------SKDGLSLKWSQWV------------PDQINKYIIQR-----------KNSFSQDWEQIH---STIFGENCFVEMILSENFSRQLRILSLDDNKT--ELHDGYNILYIPSKDECIPTIPENLQ-----VNDLT------------NYHEIFWSESKSIEIVDS------PITYSLQSKVNNQF-----WFTITEKLDKCFYTNTRIDKYGVTG----YRV--LARNSIGSSPFSMEVFTKSLINILSNEQIIKSLRYFVINPREIEIKWHLCESIFD------------------SGIT--TEDLSFQIEKKTVKEGSDWVP----ISNIVERNSILISITFEDENLF-RIQPFYRDEKLSASRIFRMYVSKDLLVPDMSFTRPNLVIDSVTSCAIEWPEPELQSGFSPDGIEICVPSVLLVDLQYEIQFVVVDPIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTID--DTVIPGSNGEREITLSWSPPRISP--DLYIPFTVDVECR-----------PVNYSY----------SDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKI-----RRSDNLNSPTTEKAMMLQEKHCLAVP----MFCCLSQKAELKFTKLMEYKLD---KITWTFNNAKVDVND-------ERYKIFSAETYGIYFI-IKNLEEDDFGEYC--ALDEVQDPIQSFILIKSDAPTILNC-LPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVI----TEDKEQG-----TYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINN-MG--IGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIM----------------------------------TGKY-----NEILKLCGFSNAVPKEDFGSRRHMGLTSP------FSAPELL---------KGEP---IQFNSDMWSIGILTFLCLHG-------H---------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQI 10405 + +D SP E L CT +++T E L + +R PT +D WL D ++ R+ +L++ +++ AG YS++ ++++ + P P+ +K +F L I P +P F R P + + E AK N EI D E ++ W DN ALTIP G Y ++V + + L + R++IS + S + PLFTK+L+D E+ + +R R+M +P I+W +G + + R+K+ ++ N +L I A ED GRYCC+ TN LG TE V+ V D++ KE S+ P AP + +++ L W + + + + I + K WK I+ L ET S+S P E +R V +E+G S + IP RA P +P KP I F++A V I W + + +P +G++ Y++E+++ +S W+ V+ +L + Y+ L PG S RV+A N FG S P+ ++ +D L P+ +PPW+ L QP + W+ A +PEFC SCV G+ P Y++E+R GR W+ +++ E T L + DDA+ E R+ C NK+G++GPT+ RL A+ + FR + K T++ D ++ ++I + + +G+ L W ++ P+ +Y I++ N+ DW+ + I+GE+ F+ + + R+L+L++ +T DGYN + IPS E +P+ P +L VND T N H + S S E+V++ P+ + + + W + E T + +D+ G YR+ + R GSS S + T L + L E I+ +R ++ P EI+++W L ++ D SG +E +SF +E + G DW P I + ++L + + ++ R+ ++ + SR R+ V D + PD +F +P + +++V I W EP++Q +S + + P L + Y +Q + QW+ + L+E + W P+P Q Y R++ NQFG+G+PS+ V++ PQ++IPD SFIR +I+ ++ GS L W PR P T +V+ R PV ++ DE W V +TN+K+ R+ + LDP + LRIV VTD+G G PS ++K+ +R +++ A P ++ + + EL+ + L + D + +W+ N+ +++ + RY+ + ++T + + + NL E DFG Y A++ + FI+ K+DAP L +P ++ LH +F + +DA P + W R+ K++ S+RT I + KE SL + +CI D G Y++ AEN G + +RV+ P K + DV YY +++L KG S +++I+K T E++GK + +++ +G G EF+C+ + H N+V++ DAI + D LVL+ E+L G +L + + ++W ES ++ Q+++A+ +LH V HLD++PEN++ T ++ + ++KL GFS+A P + + + P +SAPE+L EP + +DMWS+G+LT++ L G H L +F D D+IS++A F+R L + G R T+++ L H W N+ ++Y ++++ Sbjct: 2556 RSEDTPATSPFGFEKLRCT--DLSTPITEGSNLELVARFPTFGLDYDENDFQWLADGNAVSNKGSLVRVDTDETQGHVSLVIPNIQPEHAGTYSIRFSDNAQKRIKDNAPTTPPMGDLSKALVFPPLVILKRAMSCSERWQPSKYRP--SAFDRELPPSTSIK---EGEHAKLEARLGRNHEIFDHEWLVNGKPILPEFTSDYTIWRADNLLALTIPRMRRDLAGIYELRVFGEQDVYTTSTDLIVEPSRAKISSYKLTSADGLKPLFTKRLQDYEVDVGDCVRFTARVMAEPPAVIVWKHNGSIVTG---DHRIKLFNDDANPSLTIRHARPEDRGRYCCIATNALGRVDTEGVLQVHDTDRYVPLGNEFDAGGSVAGRKEIGGSKRTALPRTAPEVALVSMSVSNIDLRWKPIQSDEGVTYIVELSKDGG---KWWKPIITGLRETHASVSEELASPLEPVQIRVVGENEFGTGPASAPPVRIPARACIPTMPQVKPDIEFEEAASVLIKWPKATASIMEHTLLTEHVISPSAMLGQVWYAVEVREGAQSEWRRVATNLKNQFYTYHLRPGASTAIRVVAANRFGESSPTPIGLTHLDPNSLAPNLDFNPPWVSLSRPVSDDGSTYEIQPLGVTVYWKPAYMPEFCSSCVRGLEPMYRLEWRRGRSGMWQALADDLTDPEAGFRLPTDLVLALQDDAKRMKDSRSLVTLNSQAIELRLFCWNKYGESGPTKPCRLVASEL----FRG-QLYKNSTVMDKDSMQLSQITDVLQELDQLPVMSANDRCSRLLTRISSLSTTEGIGLSWEKFTLTGLPKASGDQPPEPHGRYRIEKYIARPTSPMDSPNTNQTDWKVASLDAAVIYGED-FILDTRPDKEEQIYRLLALNETETCSMWVDGYNRIRIPSLSELVPSAPTDLTIQCVPVNDSTISAENHINWKPANQHPLLVELSPSSELVEAKELANPPLDLRYRIEARSTLSELSPWRQVAEVYGG---TTSVVDRKAEPGLALIYRITPINRFGEGSSVTSPPIRTPILYSAL--EGCIEDVRSVILGPTEIQLRWRLGDAAIDALKHDQPNTWGRKRSLCRSGSVDYSERVSFTVEVRGGYAG-DWSPAVEQIQGDLNAKALLQDCHYLEHDISCRVVALIDGQRSAPSRPIRLNVRADAMTPDYTFVKPKVHVETVEEYVISWDEPDVQEIYSSHTLGLTTPQTLQRGMNYAVQV-------------QRESKPQWETIATQLKEPHYTWAQPNPLQAYHVRVLPANQFGTGIPSRSVRVEPQVVIPDLSFIRPSIEAPADILAGSTAPE---LVWQLPRAYSLEKTLTPVTYEVQVRGVANASRLALGPVPHAVHSASRQSAADDDETVWRVLETNVKRTRLPLGRLDPEQEFWLRIVAVTDYGRGAPSQSVRKLVDLAAKRQQRMSASIVTIHEATPVSPTFADPKGTVLYAPVGGRLELR-SNLQTIQPDADIRFSWSLNDRPIEIPETAQQNRLSRYQSYVSKTSDVAVLQVHNLTESDFGVYICKAVNIRGSTTKEFIVKKADAPVFLEVPVPVMTIKLHCSFELPCWVDAVPTATLYWTRDSKRVGESHRTKIGSRMSRTKEDAQCFTINASLSVDRCIYQDAGLYTLVAENIAGRVQTSCLIRVEESPIPKYPTLRWTDVGLHYYVLRRLEKGDISELRLLIDKQTNQEYVGKLYFLDDPIGRVAGAREFECLSRLCHSNVVQLHDAI-VSDNVLVLVMERLTGPNLLKAMLHCNNWSESATASVVRQVLEALQHLHCEGVVHLDLQPENLLFARNVTAETWDGQTSYTDLFKALSPLVSDTMGLRETDRHKMSVLSSLIKLVGFSSAEPLVNKSNADPVYCYPPQRFRPEYSAPEVLVAASQSASTDAEPPILVGPAADMWSVGVLTYVLLTGWCPFFDMHTSEPLREQILSASFTMDL----SEFDSISDNAKQFVRDLLQINPGSRPTATECLQHPWLSTLKNSDGQDVEYRLERL 4527 HSP 2 Score: 100.523 bits (249), Expect = 1.099e-16 Identity = 71/242 (29.34%), Postives = 118/242 (48.76%), Query Frame = 2 Query: 11618 LFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSN--NVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKL------SMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPL 12319 L + S+G +++ ++PGG L VL++R+ Y+EF+++ +QLL +++L+S HG I P IL +RR++ DI L G F G+ +E + S F APE SD+WS+G L++LL+ P + +++ + T P H P + LH FSK ++K V+N L+ P RG+ D+WL WF + + Q ++ TP+ Sbjct: 5121 LTNDAVKPSIGVSVSY--WIPGGQLFDVLVSRTEYTEFSIMRWTQQLLMALRWLYSKLFGRPHGAIIPRHILAARRSSTLPDIVLTG-----FGGSNEE-----INGRSEFTAPEVSQGETISVFSDLWSIGALNYLLMTGNCP--DAKLAETSYKVLAETTTDEEKPKLTGHQGDPHIPHYIDFKKLHMFSKPAKKLVYNCLQLLPKKRGHIDFWLESRWFDISTENV-----QRLTRTPI 5343 HSP 3 Score: 97.4413 bits (241), Expect = 1.205e-15 Identity = 135/525 (25.71%), Postives = 222/525 (42.29%), Query Frame = 2 Query: 725 KRNPRESFREDILQISNKNQESTMKRKYALADLIECDREYCATXXXXXXXXXXXXXTENEFGVEIDSLFEEVCKLIVE------------------LVEFHENLILPELSSCVMIP-------IRVANILKNQKLQFYRYSEFQSQWX--------XXXXXXXXXXXXXXFVKNVNTI-----EKSKFSVLSFNDLMLKVENKLPQYNLFLFDIIRYTGRIDGEVNDLQKAITVFQKIRRRNQEKVYLSKLIEKTN------INI-SNERFIRVTNQVMISETQIMSKSYENLQFIREEM--CSLILLKNYLLCV--SDLSQPTD-RKIMNLDYTKIYTKENYERQNELI-IW-SKMNKLEFRIFILYFPNKVSKLGWLRDLTKRLK---KKGIDEIFVSSTEYDIQYKQYLGKNQRLVATEMESIGLESASLENECSSISDQIEDLTSMADSITDVR--FESAILDMPS----------SMTSGSYKTAPETFKSTMDKASRPISGISQDSVSTLDGVRTPFSD 2098 KR+PRE FRE+++ ISNK QES MKR+YAL +LIE +REY L + D L FG + E + ++ +++F E +L EL++C M P IR A L++ + F Q L +L D S +N ++ +++ + +L + +L Y + L D+ RYT + L+ +TV + RR +E + I +T IN+ N+R + ++ T + + L+ I E LILL ++L + +LS D I+ LD +I E ++Q IW ++ + +I +Y + +S+ W+ D+ + L + G +E V S + L K + A ME S SLE+ D ++ + S+ D+ + ++D+ S S TS SY TA E ++ S +S +TLD VRTPFS+ Sbjct: 420 KRDPRELFREEVITISNKQQESKMKRRYALTELIETEREYVKALTPLLDAL-------TRFGTRVTLHLGEATEETIDIPKPLQQCIRNLRDKLKKIIDFTEKTLLDELAACTMNPPSAAECFIRNAAALEHYSIYLLHLDAFVKQLTLINGPDSDALFVLQDSSSPPRSPTENGDSTSALCNQRTSITYKYLLELFDLPKLRLLAYRVLLRDVARYTSQAGASTEQLEHGMTVIARTSRRTEETLMFWTKINQTTSECVEWINMYKNKRTGNLMPPALVRLTDLETNIRTGLRPISSETKKGRLILLPQHILFLQKQELSDTWDISWIIKLDGLRIGASELSDKQPPWFEIWNTEGSDPTKKIVRIYCADTLSQNAWMEDIRRALMNLLQCGDEETLVDSAVVSAHEEADLRKRLKF-AHVMELPAFRSDSLEDFFVDALDDLQKQQATFSSVDDIHNGQKPQVVDLVSMSTATSKKQDSSTSSSYHTA-EELSDHQTSCAKETSTTLYESYTTLDDVRTPFSE 935 HSP 4 Score: 91.2781 bits (225), Expect = 7.470e-14 Identity = 70/260 (26.92%), Postives = 111/260 (42.69%), Query Frame = 2 Query: 10721 FTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISI----------------------------SWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVG-IFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAID-DVIYRIDIRTIDSRNKIRNWKTIGYSVDNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVF-----------QNKIRNIHSLKQALIFNRKWMLTSRQS 11377 F PL+D F S + +CQL+ P I +WY LL+D ++L GG+L + G + +C+ R + + +T ARL++ D P P + + + E L+ W+P +D D+IYR+D + + N W T+G++VD R+L NL Y R+ A N G+ YSIA+S F ++ R+ + +R+WMLT RQS Sbjct: 4707 FASPLRDAYFNIHSGEAR----FSCQLAGFAHLPPGIHGHREAIAELYPTDVVNAQTGHSSATVAAWYLGGCLLSDGPGVQLGTGPGGWLWLYLSELNVDQAGTVVKCVVRNRAGKAKTQARLLIADPPKPPGRPGMAEVHPTEALITWAPSDVDVDGDLIYRVDAK-FAANNGPAAWHTLGFTVDCRFLAMNLQPGLCYRMRVSAGNSCGWGNYSIASSEFYTPTDHPSRFDSSEDRSSEVISLLSKDDREWMLTWRQS 4961
BLAST of Serine/threonine kinase vs. Ensembl Cavefish
Match: spegb (striated muscle enriched protein kinase b [Source:ZFIN;Acc:ZDB-GENE-081104-517]) HSP 1 Score: 128.642 bits (322), Expect = 1.325e-28 Identity = 130/595 (21.85%), Postives = 245/595 (41.18%), Query Frame = 2 Query: 8708 REITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEG------WSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGEYCALDEVQDPIQSFILIKS-------------DAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDA---HPEK-------KSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFF--EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI----LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 + ITLSW PR +D P Y+ ++ W++ +++K+ + L + Y RI+ +T KPS ++ D P ++A ++ +K + ++E + IT T N+ +V +R + + G++ + ++ + C + +F S PT + + + +++ E +V ++ +P P++ W +N + SS+ T + +D E SL++ D G Y+ A+N G K L V PEK +++ + + D Y K++ +G++S + V K ++E+ KF E + ++ H I+ DA + V+I ++ L + +T+ S E+++R I Q+++ + +LH+H + HLDIKP+NI+M +I + C + T F APE++ P+ +D+W +G+LT+LCL G E D+ + E + + A F+ K LL+ R SS+ L H WF Sbjct: 874 KTITLSWKKPR---------RLDPSIDPGTLMYAVQQQALGSIQWTIIASSLKQTTYTVTSLSKGVRYAFRILSITSKAFSKPSNATDPVQLIDR--GPYVQEAPVIIDKPDVVY----------------VVENQSVSITVTLNHVNANVTWKRRGVTLSNRVGLFEMSMPDDDQHMLKLCKVKYSDVGPLTFTASNSYGTDSCLLTLELAAPPTFESIMEDLDVSVGETPRFAVVVEGKPIPDIFWYKNDVLLSESSHFTFVYDDNE---CSLVVLNTQPDDSGVYTCTAKNLAGSVSCKAELTVHTSMTKPEKDRPMEDKETMLRRMRRLTDYYDVHKEIGRGAFSYVKRVTHKVGKMEYAAKFISARAKRKASALREMNILSHLDHERIIYFHDAFE--KKNAVIIITEICHEELLDRLTKKSTVMEAEIRSSIRQILEGIHFLHQHDILHLDIKPDNILMADSTMKITPDEAQYCKYG----------------TPEFVAPEIVNQTPVSKATDIWPVGVLTYLCLTGVSPFAGENDRSSVFNIRNYNVAFEESMFADLCHEAKGFVIK-LLVADRLRPDSSECLRHPWF 1419 HSP 2 Score: 98.5969 bits (244), Expect = 1.787e-19 Identity = 72/264 (27.27%), Postives = 125/264 (47.35%), Query Frame = 2 Query: 9626 YYTMKKLAKGSYSRCQIVIEKSTQIEFIGKF--FEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSP-----FSAPELLKGEPIQFNSDMWSIGILTFLCLHGH---------------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 Y M + A+G + + E +T F+ K +E + E++ ++++ H I+ + +A P +YLVLI E G + + + E V I Q++Q + YLH R+ HLDIKP+NII+T Y ++K+ F +A + F + P + +PE+LKG+ + +D+WS+G++TF+ L G L F+ +LY +S SA +F++K L R + D ++ W Sbjct: 2481 YTFMDEKARGRFGVIRECRENATGNLFMAKIVPYEPESKQTVLQEYEILKSLHHDKIMALHEAYVTP-RYLVLISECCAGKEILYSLIDRFRYSEDDVVAYIVQVLQGLDYLHNRRILHLDIKPDNIIVT--YMNVVKIIDFGSA---QTFNPLFLKQFSPPIGTLDYMSPEMLKGDVVGPPADIWSVGVMTFIMLSGRLPFTDSDPAETEARILAAKFDLSKLYQN-----VSQSASLFLKKILCSYPWARPSIKDCYNNSWL 2733 HSP 3 Score: 81.6481 bits (200), Expect = 2.023e-14 Identity = 99/460 (21.52%), Postives = 181/460 (39.35%), Query Frame = 2 Query: 5756 IKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAE----NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTK-DGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDS---------------------SRIIVKPLCAPVLTAEYSKGADVILSWTSVATT-DTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFET------VSNIIEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSL-SLEPGVSYMFRVIAFNDFGISEPSQSL--ISRIDRLKLVPDFSV 7027 I +P++D+ ++ ET FE V W + + I M F C L + + E G YT +++ + S +L ++ I PLFT+KL +E++ N R +C++ P PK++W+ D ++S+ ++IL E +L+I+ +D G Y + N G D A + V + P S R + P+ + +G + +L T++ +N K + ST +K+ + + + S C + + V ++ G T V++++ P P P I + +SW K + L P G +MY+++ + W I+++ L Y++ SL GV Y FR+++ S+PS + + IDR V + V Sbjct: 545 IVRPVRDVLVKAG-ETAVFECHVIGPQDVDVDWLSDGKLIQPALLNCKMHFDGRRC----RLLLNSVHEDDSGTYTCKLSTAKEELTSSAKLKVL------------ASIEPLFTRKLDMLEVIEGRNARFDCKVSGTPPPKVIWSHFDHPLIESE----DIRILKEGGRHSLVISHVSSDDEGFYTVVARNPHGEDECSAELYVQEPRPAISSQMAKLEKMPSIPEEPEVPESEVERFTMPDFVKPLYDLDVIEGKEAVLKCKVAGLPYPTISWFHN---GKKIDSTEDRKMTQFRDIHSLVIRSVCH--AHGGVYKSVISNKMGKATCYAHLYVTDVLPDP--------PDGAPVIESITGKTITLSWK--KPRRLDPSIDPGTLMYAVQQQALGSIQWTIIASSLKQTTYTVTSLSKGVRYAFRILSITSKAFSKPSNATDPVQLIDRGPYVQEAPV 968 HSP 4 Score: 57.7658 bits (138), Expect = 3.407e-7 Identity = 47/176 (26.70%), Postives = 74/176 (42.05%), Query Frame = 2 Query: 10781 VTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSV-DNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNK 11305 VTL+C + GS I+W K+++ L D R+ + G I+ T+ D G++ C+A +S +L L +P +P V + L+ W P + Y ++ RT NW + V D Y + +L Y R+ NK G PYS S +K Sbjct: 2174 VTLSCLPA--GSPHPHIAWMKDKKPLEIDQRMNMISCPDGRQLLMIMKTTKNDAGLYECVATNPLASISSSCKLSLARLPNRPGTPEVPQKYKNTALVVWRPS-DTMSPCTYSLERRT----EGESNWLIVATGVADCYYNVNDLPTGAAYRFRVACVNKAGQGPYSNLQSQIHSK 2342 HSP 5 Score: 53.1434 bits (126), Expect = 9.496e-6 Identity = 36/133 (27.07%), Postives = 66/133 (49.62%), Query Frame = 2 Query: 11657 ITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSI----FKAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 + E G +L L+ R YSE VV I Q+L + +LH+ ++H +I+P I+++ +K+I + Q + L P I + +PE + +DIWS+G+++F++L+ +LP Sbjct: 2551 VLISECCAGKEILYSLIDRFRYSEDDVVAYIVQVLQGLDYLHNRRILHLDIKPDNIIVTYMNV----VKIIDFGSAQTFNPL----FLKQFSPPIGTLDYMSPEMLKGDVVGPPADIWSVGVMTFIMLSGRLP 2675
BLAST of Serine/threonine kinase vs. Ensembl Cavefish
Match: dapk2b (death associated protein kinase 2 [Source:NCBI gene;Acc:103026419]) HSP 1 Score: 117.087 bits (292), Expect = 4.743e-27 Identity = 85/277 (30.69%), Postives = 135/277 (48.74%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFE-----INNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHG----------HLKVNFEG-DQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNA 10378 V D Y ++L G ++ + EKST +E+ KF + + G+ R E + +Q++ H NI+ + D +VLI E + G L +++ Q E + I Q++ V YLH R+ H D+KPENI++ + +KL F A ED +++ T F APE++ EP+ +DMWSIG++T++ L G N G + ++E+ + S A FIR+ L T +RLT +L+H W IKP N A Sbjct: 14 VEDFYEIGEELGNGQFAIVKRCKEKSTGVEYAAKFIKKRQSRASRRGVRREEIEREVNILQHLQHPNIISLHDVYENRTD-VVLILELVSGGELFDFLAQKESLSEEEATEFIKQILDGVQYLHSKRISHFDLKPENIMLLDNNVPLPRIKLIDFGLAHKIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGESKQETMANISGMNYEFDEEFFGSTSELAKNFIRQLLTKDTRKRLTIEGALNHPW-IKPVNPRQA 288 HSP 2 Score: 62.003 bits (149), Expect = 6.120e-9 Identity = 50/203 (24.63%), Postives = 87/203 (42.86%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRY-----ESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFK 12262 E V GG L L + SE I+Q+L +Q+LHS + H +++P I++ IKLI G + E K +IF PE+ I Y E+D+WS+G+++++LL+ P + ++ ++ + N + + F + S+ ++ F+ L K R + L H W K Sbjct: 99 ELVSGGELFDFLAQKESLSEEEATEFIKQILDGVQYLHSKRISHFDLKPENIMLLDNNVPLPRIKLIDF------GLAHKIEDGVEFK-NIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGESKQET-----MANISGMNYEFDEEFFGST--------SELAKNFIRQLLTKDTRKRLTIEGALNHPWIK 281
BLAST of Serine/threonine kinase vs. Ensembl Cavefish
Match: si:dkey-240h12.4 (death-associated protein kinase 2-like [Source:NCBI gene;Acc:103045656]) HSP 1 Score: 112.464 bits (280), Expect = 1.545e-25 Identity = 78/290 (26.90%), Postives = 146/290 (50.34%), Query Frame = 2 Query: 9593 VQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEI-----NNMGIGRS----EFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNA---VPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-------------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAA 10381 Q N+ +V D Y + L G + + + + E+++ + + GKF ++ + +G+ R E + +Q + H NI+ + D + +V++ E ++G L +++ + + E + + Q+++ V+++H ++ H D+KPENI+++ K E +K+ F A P E++ R + T + PE++ EP+ SDMWSIG++T++ L G F+GD + E S+ A FI K L+ + ER+T+ + L H W IKP AA Sbjct: 2 AQFNLQNVEDFYEIGEILGSGHFGQVRELRERASGVSWAGKFVKLRRSVSSRLGLERKSVEREVEILQALQHTNIMALKDVFESRAE-VVIVVELIRGGELFDFVAEKENLTEIEAIEFLKQILKGVAFMHSKQIAHFDLKPENIMLSDKKVEHPEIKIIDFGLAQRLTPGEEY---RSLCGTPQYIGPEVINYEPLSVASDMWSIGVITYILLSGL--SPFQGDTDEETLRNIVDMKYEFEEQYFSQTSDMAKDFIEKLLIKEPSERMTAEECLLHPW-IKPLTRKQAA 284 HSP 2 Score: 72.7886 bits (177), Expect = 1.965e-12 Identity = 53/229 (23.14%), Postives = 104/229 (45.41%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYE-----SDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPLVDFVNAN 12340 E + GG L + + +E + ++Q+L + F+HS + H +++P I++S + + +IK+I Q + +E SL P+Y + YE SD+WS+G+++++LL+ P D ++ ++N + +F + S ++ F+ L K P++R A+ L H W K P T + +++ SS + +F N Sbjct: 94 ELIRGGELFDFVAEKENLTEIEAIEFLKQILKGVAFMHSKQIAHFDLKPENIMLSDKKVEHPEIKIIDFGLAQRLTPGEEYRSLCG-------TPQYIGPEVINYEPLSVASDMWSIGVITYILLSGLSPFQGDTDEET-----LRNIVDMKYEFEEQYF--------SQTSDMAKDFIEKLLIKEPSERMTAEECLLHPWIK--PLTRKQAANRSRSSINMKNFKKFN 300
BLAST of Serine/threonine kinase vs. Ensembl Cavefish
Match: si:dkey-240h12.4 (death-associated protein kinase 2-like [Source:NCBI gene;Acc:103045656]) HSP 1 Score: 112.464 bits (280), Expect = 1.545e-25 Identity = 78/290 (26.90%), Postives = 146/290 (50.34%), Query Frame = 2 Query: 9593 VQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEI-----NNMGIGRS----EFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNA---VPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-------------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAA 10381 Q N+ +V D Y + L G + + + + E+++ + + GKF ++ + +G+ R E + +Q + H NI+ + D + +V++ E ++G L +++ + + E + + Q+++ V+++H ++ H D+KPENI+++ K E +K+ F A P E++ R + T + PE++ EP+ SDMWSIG++T++ L G F+GD + E S+ A FI K L+ + ER+T+ + L H W IKP AA Sbjct: 2 AQFNLQNVEDFYEIGEILGSGHFGQVRELRERASGVSWAGKFVKLRRSVSSRLGLERKSVEREVEILQALQHTNIMALKDVFESRAE-VVIVVELIRGGELFDFVAEKENLTEIEAIEFLKQILKGVAFMHSKQIAHFDLKPENIMLSDKKVEHPEIKIIDFGLAQRLTPGEEY---RSLCGTPQYIGPEVINYEPLSVASDMWSIGVITYILLSGL--SPFQGDTDEETLRNIVDMKYEFEEQYFSQTSDMAKDFIEKLLIKEPSERMTAEECLLHPW-IKPLTRKQAA 284 HSP 2 Score: 72.7886 bits (177), Expect = 1.965e-12 Identity = 53/229 (23.14%), Postives = 104/229 (45.41%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYE-----SDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPLVDFVNAN 12340 E + GG L + + +E + ++Q+L + F+HS + H +++P I++S + + +IK+I Q + +E SL P+Y + YE SD+WS+G+++++LL+ P D ++ ++N + +F + S ++ F+ L K P++R A+ L H W K P T + +++ SS + +F N Sbjct: 94 ELIRGGELFDFVAEKENLTEIEAIEFLKQILKGVAFMHSKQIAHFDLKPENIMLSDKKVEHPEIKIIDFGLAQRLTPGEEYRSLCG-------TPQYIGPEVINYEPLSVASDMWSIGVITYILLSGLSPFQGDTDEET-----LRNIVDMKYEFEEQYF--------SQTSDMAKDFIEKLLIKEPSERMTAEECLLHPWIK--PLTRKQAANRSRSSINMKNFKKFN 300
BLAST of Serine/threonine kinase vs. Ensembl Cavefish
Match: trioa (trio Rho guanine nucleotide exchange factor a [Source:NCBI gene;Acc:557667]) HSP 1 Score: 116.316 bits (290), Expect = 6.547e-25 Identity = 98/383 (25.59%), Postives = 183/383 (47.78%), Query Frame = 2 Query: 9293 PTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYT-MKKLAKGSYS---RC-QIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNE-ILKLCGFSNAVPKEDFGSRRHMGLTSP-FSAPELLKGEPIQFNSDMWSIGILTFLCLHGH---LKVNFEG--------DQLYNEDSNDAISNSACVFIRKCLLLKT--GERLTSSDSLSHEWFIKPGNNLNAA 10381 P +L L + + E ++ ++ +P + W+ ++ ++ E G +L I D G Y+ A N IG +LRV + P +++ D + +YT + +L +G ++ RC Q +++ ++ + K + E ++ + H +IV + D P Y +++ QG L +YI + E +V + +++A+ YLH R+ HLD+KPEN+++ ++ ++KL F +AV + + H L SP F+APEL+ G+P+ SD+WS+G++T++ L G L + E D + ED +S +A F+ CLLL+ +R ++ L W ++PG +A Sbjct: 2650 PEMLVPLSDVTCDKGECVTLRCKVCGRPKATITWKGPYQNTLTNNGHFSIAYSETGEATLRIVGVASEDDGVYTCIATNDIGSVTSSASLRVLS-PSSDGIRVMWKDNFESFYTEVAELGRGRFAVVKRCDQKGSKRTVAVKLVNKKLMKRDQVT--QELSILKRLQHPHIVCLQDTFETPGSYALVLEMADQG-RLLDYIVSWGNLTEEKVAFYLRDILEALHYLHNCRIAHLDVKPENLLVDQSSSQPVVKLTDFGDAV-QLNSAHYVHPLLGSPEFAAPELVLGDPVSLTSDLWSLGVVTYVMLSGASPFLDESVEETCLNICRLDFSFPEDYFQGVSQAARDFM--CLLLRVEPSKRPPAATCLQEPW-LRPGGGRRSA 3024 HSP 2 Score: 59.3066 bits (142), Expect = 1.389e-7 Identity = 61/290 (21.03%), Postives = 127/290 (43.79%), Query Frame = 2 Query: 11417 SSDDIRM---NVIREHYSTLSQKSSG-FAVLKL---KNTNVNFPEYIV-QRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFK 12262 SSD IR+ + Y+ +++ G FAV+K K + +V ++ K + + + R+++ H L + G+ E G LL +++ +E V +R +L + +LH+ + H +++P +L+ + ++Q +KL + + + L P F APE SD+WSLG++++++L+ P ++++ ++ ++ C L P +F+ S+++R F+ L+ P+ R A L W + Sbjct: 2745 SSDGIRVMWKDNFESFYTEVAELGRGRFAVVKRCDQKGSKRTVAVKLVNKKLMKRDQVTQELSILKRLQHPHIVCLQDTF--ETPGSYALVLEMADQGRLLDYIVSWGNLTEEKVAFYLRDILEALHYLHNCRIAHLDVKPENLLVDQSSSQPV-VKLTDFGDAVQLNSAHYVHPLLG-SPE-FAAPELVLGDPVSLTSDLWSLGVVTYVMLSGASPFLDESVEETCLNIC-----RLDFSFPEDYFQG--------VSQAARDFMCLLLRVEPSKRPPAATCLQEPWLR 3016
BLAST of Serine/threonine kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004663.1 (pep scaffold:Pmarinus_7.0:GL479759:1154:24713:-1 gene:ENSPMAG00000004240.1 transcript:ENSPMAT00000004663.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 115.161 bits (287), Expect = 3.139e-25 Identity = 116/570 (20.35%), Postives = 236/570 (41.40%), Query Frame = 2 Query: 8792 VNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCC------LSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKI-FSAETYGIYFI-IKNLEEDDFGEY--CALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIG----FAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMG--IGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNA---VPKEDFGSRRHMGLTSP-FSAPELLKGEPIQFNSDM-WSIGILTFLCLHGHLKVNFEGDQL-----------YNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQI 10405 + Y W V +N+ + L P ++Y R + V+ G +PS ++PT ++ E P F + L+ T + + ++WT + V++ ++ S+ G + + + + GE A E + ++ +++AP + + + + +SV + +P P+V+W ++ ++ + + + + SLL+ SD G Y+ A + G AE+ + +++ + + + D Y ++++ +G++ + V S K + E + ++H +V + DA + ++++ E L + + + E QV++ I Q+++ +SYLH + HLDI+P NI+M + +K+ F A VP GS ++ +P F +PE+ + P+ SD+ W +G++T++CL G E D+ ++E + S A FI + L+ G R + D L H WF K L A + D++ Sbjct: 222 LQYQVVGRSQWIVVASNVPGTSHAVRTLRPGLHYLFRALTVSPHGCSRPSPA----------SAPT---CLLPHEPFLNEPPRFVKKYEEIFAVENEPLEITCRLNHVQATVSWTRCRDGIPVDESSGEVRLSSRPGGTWALEMPRARAELLGELVCTARGEFGSDSYTAVVSQAEAPHFEVIMEDVEVQEGDPVRLSVVVHGRPEPDVLWYKDGARLAEAG-GLASVTRSGSACSLLLRDVRGSDRGLYACEARSRAGTARCMAELTVRMEKSEARQREMPEEEVRKLKDHYEILEEIGRGAFGSVRRVRALSGGSPCAAKSLPRGRVRREAAERELRVAARLAHERVVCLHDAFRS-RRRVIIVMELCSNEELLDRLVKKPALYEHQVKMYIKQILEGISYLHSINILHLDIEPSNILMADAGKDDIKISDFGFAQEVVP----GSPQYSEFGTPEFVSPEVARHSPVYKASDIWWPVGVITYVCLSGLSPFLGENDRATLLNVTRKTLNFDERTAAITSREAQDFISRVLVQDIGRRPLADDCLKHPWF-KSFTTLRAVTNISTDRL 771 HSP 2 Score: 70.0922 bits (170), Expect = 1.336e-11 Identity = 89/360 (24.72%), Postives = 148/360 (41.11%), Query Frame = 2 Query: 5927 LTIPAAGEKHCGKYTIQVANDMGCVR-------SDGRLSLMLRSEISEQ-MMESCC-----------IAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTS----VATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPP-----DKPTIIFK------------DATC------VKISWMRGKCKNLTP-EESIGKIMYSLEMKDNPKSSWQI 6865 L++P A + G+YT+ AN G V S+ R S IS++ MM S AP F++ L D+ +L L CR P++ W + GE + L RV +E F LII A++ D+G Y C+ +N G A + V D+ P D I+ +T + V LSW A ++ ++ Y ++ Q + + W + N+ T++++ + L P +L R + +S +G S P A + +LP + P + K + TC +SW R C++ P +ES G++ S P +W + Sbjct: 21 LSVPHASAEDEGEYTVTAANTHGEVSCSCTLIVSEPRAPHA--SNISKRDMMPSIAEEPELGEAERDAAPDFSQPLCDVAVLEGGCAVLECRGQARIPPQVSWLRQGEQVP---LGGRVTSKEENGTFRLIIQSAKLADAGVYKCILSNSAGRAFCHAHLHVVDATPGPPDGPPIVTD------VTDD-----SVTLSWKPPKAFQAFSEPGSVTYALQYQ-VVGRSQWIVVASNVPGTSHAVRT--LRPGLHYLFRALTVSPHGCSRPS-----PASAPTCLLPHEPFLNEPPRFVKKYEEIFAVENEPLEITCRLNHVQATVSWTR--CRDGIPVDESSGEVRLS----SRPGGTWAL 350 HSP 3 Score: 53.9138 bits (128), Expect = 1.174e-6 Identity = 51/180 (28.33%), Postives = 82/180 (45.56%), Query Frame = 2 Query: 10676 SADRLSVSNTTKEL-LFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQ-----PEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNRY 11197 S+ R S+++ ++ L FTV LKD+ VTL C S GS +ISW K+++LL D R++L G TI+ A D G++ C+A +SL T++ + PP PE V+ + L+ W P + A + Y ++I WK + + + Y Sbjct: 1444 SSSRDSLASVSQSLPAFTVKLKDELLVEGEP-----VTLCC--SPTGSPAPTISWLKDRKLLEPDERVRLAGSADGRQLLTIVRAGMADAGVYECMA-VNSLGIATTSCTLARAEPPSWTGAAPEVPQVFESG---ALVVWKP-VQARTPLTYCLEITV----GPGEPWKEVASGLSDTY 1607 HSP 4 Score: 53.5286 bits (127), Expect = 1.332e-6 Identity = 47/175 (26.86%), Postives = 71/175 (40.57%), Query Frame = 2 Query: 6077 PLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLI-ITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSC 6598 P FT KLKD ++ E + L C P P I W KD + L+ + RV++ L+ I A + D+G Y C+ N LG TT + +EP + AP + + GA V+ W V L I WK++ L++T + + C Sbjct: 1458 PAFTVKLKDELLVEGEPVTLCCSPTGSPAPTISWLKDRKLLEP---DERVRLAGSADGRQLLTIVRAGMADAGVYECMAVNSLGIATTSCTL--ARAEPPSWTGA--------APEVPQVFESGALVV--WKPVQARTPLTYCLEITVGP---GEPWKEVASGLSDTYHHVGGLC 1614
BLAST of Serine/threonine kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000175.1 (pep scaffold:Pmarinus_7.0:GL476590:10927:25170:1 gene:ENSPMAG00000000155.1 transcript:ENSPMAT00000000175.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 97.4413 bits (241), Expect = 2.769e-21 Identity = 68/269 (25.28%), Postives = 127/269 (47.21%), Query Frame = 2 Query: 9629 YTMKK---LAKGSYSRCQIVIEKSTQIEFIGKFF---------EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSH-WCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAV---PKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQL-----------YNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFI 10354 Y++K+ L G + R +E+++ + K E+NN E + + H N+++++DA + + VLI E + G L + I + E I I Q+ + + Y+H+ + HLD+KPENI+ + +K+ F A P+E + H G T F APE++ + + F +DMWS+G++ ++ L G E D +++++ + +S A FI + L+ + R+++S L H W + Sbjct: 31 YSIKQKDVLGGGRFGRVHKCVERTSGMTLAAKVIKAKGVKEKDEVNN------EISIMNQLKHNNLLQLYDAYESKNDF-VLIMEYIHGGELFDRIVSEDYNLTELDAIIFIRQICEGIHYMHQQYILHLDLKPENILCVNRKGNQIKIIDFGLARRYKPREKL--KVHFG-TPEFLAPEVVNYDYVSFPTDMWSLGVIAYMLLSGLSPFMGEDDNETLTNIVNVNWDFDDEAFENVSEEAKDFISRLLIKEKSGRMSASQCLKHNWLV 289 HSP 2 Score: 60.077 bits (144), Expect = 4.980e-9 Identity = 48/204 (23.53%), Postives = 91/204 (44.61%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSV-YSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKIL-ISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYE-----SDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWF 12259 E++ GG L +++ +E + IRQ+ I ++H ++H +++P IL ++R+ NQ IK+I K +E L H F PE+ + Y+ +D+WSLG+++++LL+ P + + D++ + N N S+ ++ F+ L K + R +A L H+W Sbjct: 108 EYIHGGELFDRIVSEDYNLTELDAIIFIRQICEGIHYMHQQYILHLDLKPENILCVNRKGNQ---IKIIDF---GLARRYKPREKLKVH----FGTPEFLAPEVVNYDYVSFPTDMWSLGVIAYMLLSGLSPFMGE--DDNETLTNIVNVNWDF-----------DDEAFENVSEEAKDFISRLLIKEKSGRMSASQCLKHNWL 288
BLAST of Serine/threonine kinase vs. Ensembl Sea Lamprey
Match: mylk3 (myosin light chain kinase 3 [Source:NCBI gene;Acc:561635]) HSP 1 Score: 96.2857 bits (238), Expect = 3.197e-21 Identity = 74/273 (27.11%), Postives = 130/273 (47.62%), Query Frame = 2 Query: 9644 LAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIG---RSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNA---VPKE----DFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH---------------LKVNFEGD-QLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAAL 10384 L G + R EKS+ + K + + ++E + ++H N+V++FDA + LI E ++G L I S E + + Q+ + V Y+H+ + HLD+KPENI+ ++ +K+ F A P+E FG TS F APE++ E + F +DMWS+G++T++ L G + N+E D ++++E S DA + ++ K RL++ +L H+W +K +NL++ L Sbjct: 33 LGGGRFGRVMRCQEKSSGLTLAAKVIRVKSPKEKEEVKNEINIMNQLNHVNLVQLFDAYESRSD-ITLIMEYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSRWGYQIKIIDFGLARRYKPREKLKVSFG-------TSEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGDDESETLNNIVTSNWEFDGEVFSEVSEDAKDFITNLLVKG----KKRWRLSAKGALQHQWLLK--SNLHSRL 291 HSP 2 Score: 59.6918 bits (143), Expect = 4.866e-9 Identity = 37/135 (27.41%), Postives = 70/135 (51.85%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESL-TTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDS 12070 E+V GG L + ++ +S SE V +RQ+ + ++H ++H +++P IL R + IK+I + K +E L + S F APE + +D+WS+G+++++LL+ P + D S++ Sbjct: 102 EYVEGGELFNRIIDQSGLSELDTVLFVRQICEGVHYMHQQYILHLDLKPENILCLSR--WGYQIKII---DFGLARRYKPREKLKVSFGTSEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGDDESET 231
BLAST of Serine/threonine kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010891.1 (pep scaffold:Pmarinus_7.0:GL476752:24038:27952:-1 gene:ENSPMAG00000009868.1 transcript:ENSPMAT00000010891.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 91.6633 bits (226), Expect = 3.678e-20 Identity = 62/214 (28.97%), Postives = 104/214 (48.60%), Query Frame = 2 Query: 9749 SEFQCIQNISHRNIVEIFDAIAMPD-QYLVLIYEKLQGLSLAEYITQLSH-WCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHG-----------HLKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 +E Q + SH N++++ D + D + +VL+ E ++G L E ++ E +V I+ QL A+ +LH V HLD+KPE + + + ++ LK+ G A+ +D H F+APE++ E + FN+D W +G+L + L G +K E+ A+S A FI K L+ +RL +D+L H W Sbjct: 36 NEAQLLYGASHPNVLQLLDVYHLLDTKQMVLVTEPVEGGELFERLSGKGFALTERKVSGILKQLCLALQHLHSLNVLHLDVKPECLWLASRESDELKVAGLGCALRYQDNLKAPHQIPVPEFAAPEVVANEVVTFNTDAWPVGLLACVMLSGVSPFWDQWDSETVKKVVAATYSLPEEEFKAVSRPAREFISKLLVKAPPKRLGVADALKHPWL 249 HSP 2 Score: 64.6994 bits (156), Expect = 5.400e-11 Identity = 59/206 (28.64%), Postives = 98/206 (47.57%), Query Frame = 2 Query: 11657 ITFEEFVPGGNLLSVLMARS-VYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESL-TTHKPSI--FKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDR-GNADYWLAHSWF 12259 + E V GG L L + +E V I++QL +Q LHS NV+H +++P + ++ R +S ++K+ GL C ++ Q++L H+ + F APE + + +D W +G+L+ ++L+ P D V V T +L P F+A S+ +R+F+ L K+P R G AD L H W Sbjct: 65 VLVTEPVEGGELFERLSGKGFALTERKVSGILKQLCLALQHLHSLNVLHLDVKPECLWLASR--ESDELKVAGL-GC----ALRYQDNLKAPHQIPVPEFAAPEVVANEVVTFNTDAWPVGLLACVMLSGVSP-FWDQWDSETVKKVVAATYSL----PEEEFKA--------VSRPAREFISKLLVKAPPKRLGVADA-LKHPWL 249
BLAST of Serine/threonine kinase vs. Ensembl Sea Lamprey
Match: stk17b (serine/threonine kinase 17b (apoptosis-inducing) [Source:ZFIN;Acc:ZDB-GENE-040426-1499]) HSP 1 Score: 93.9745 bits (232), Expect = 4.640e-20 Identity = 66/264 (25.00%), Postives = 119/264 (45.08%), Query Frame = 2 Query: 9644 LAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHR-----------NIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLS-HWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYN-EILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPG 10363 L +G ++ + +E +T IEF KF G C +++H +I+++ DA P + ++++ + G + + + + E VR ++ Q+++ V++LH + V HLD+KP+NI++T +K+ F + R + T + APE+L EPI +DMWS+G+L ++ L G E Q Y + + +S A FI++ L+ R T+ L H W G Sbjct: 1 LPRGKFAVVRRCVEVATGIEFAAKFLRKRRKGQ-----DCRADVTHEMAILEAARSCPHIIDLHDAFETPTEIILVLEYAVGGEIFNQCVAEGEDAFTEVDVRRLMRQILEGVAFLHRNDVVHLDLKPQNILLTSASPLGDIKIVDFGLSRRVNSAEELREIMGTPEYVAPEVLNYEPISKATDMWSVGVLAYVMLTGESPFLGEDKQETFLNVSQLNVSYEPEVFEGVSVQAVAFIQQLLVKAPHRRATAEHCLRHPWLSARG 259 HSP 2 Score: 70.0922 bits (170), Expect = 3.563e-12 Identity = 52/201 (25.87%), Postives = 102/201 (50.75%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARS--VYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKE-QESLTTHKPSIFKAPE-YRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWF 12259 E+ GG + + +A ++E V ++RQ+L + FLH N+VVH +++P IL++ + DIK++ + V + +E +E + T + + APE YE I++ +D+WS+G+L++++L + P + + ++ ++ V N P + S + F+ L K+P+ R A++ L H W Sbjct: 73 EYAVGGEIFNQCVAEGEDAFTEVDVRRLMRQILEGVAFLHRNDVVHLDLKPQNILLTSASPLG-DIKIVDFGLSRRVNSAEELREIMGTPE---YVAPEVLNYEPISKA-TDMWSVGVLAYVMLTGESPFLGEDKQETFLN--VSQLNVSYEP-----------EVFEGVSVQAVAFIQQLLVKAPHRRATAEHCLRHPWL 255
BLAST of Serine/threonine kinase vs. Ensembl Yeast
Match: SNF1 (AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885]) HSP 1 Score: 86.6557 bits (213), Expect = 3.910e-17 Identity = 65/259 (25.10%), Postives = 123/259 (47.49%), Query Frame = 2 Query: 9626 YYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQC--------IQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSP-FSAPELLKGEPIQFNS-DMWSIGILTFLCLHGHLKVNFEG-DQLYNEDSNDA------ISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 Y +K L +GS+ + ++ +T + K IN + +S+ Q ++ + H +I++++D I D+ +++I + G L +YI Q E + R Q+I AV Y H H++ H D+KPEN+++ N + G SN + +F SP ++APE++ G+ D+WS G++ ++ L L + E L+ SN +S A I++ L++ R++ + + +WF Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKI--INKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVI--EYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNF---LKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWF 306
BLAST of Serine/threonine kinase vs. Ensembl Yeast
Match: RAD53 (DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]) HSP 1 Score: 85.5001 bits (210), Expect = 1.170e-16 Identity = 69/267 (25.84%), Postives = 124/267 (46.44%), Query Frame = 2 Query: 9644 LAKGSYSRCQIVIEKST----QIEFIGKFFEINNM-GIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGE-----PIQFNS--------DMWSIGILTFLCLHGHLKVNFEG---DQLYNEDSNDA----------ISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 + +G+++ + IE++T ++ I K I NM G+ R E + +Q ++H IV + + Y ++ E + G L +++ E R I Q++ A+ Y+H + H D+KP+NI++ ++K+ F A + + + T + APE+++G+ P ++ DMWS+G L ++ L GHL F G DQLY + + IS A FI L + R T++ +L+H W Sbjct: 204 VGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTR-ELEVLQKLNHPRIVRLKGFYEDTESYY-MVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLP--FSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWI 466 HSP 2 Score: 72.7886 bits (177), Expect = 9.311e-13 Identity = 57/210 (27.14%), Postives = 89/210 (42.38%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQ--ESLTTHKPSIFKAPEY-----RYESITRYES--DIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDP 12271 EFV GG+L+ + A E I RQ+L I+++HS + H +++P ILI + I GL Q G+ + +L P + + + YE Y S D+WS+G L +++L LP + S D L + + L R S+ +R F+ + L+ PN+R A L H W K P Sbjct: 274 EFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPF---SGSTQD---------QLYKQIGRGSYHEGPLKDF-RISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKMSP 470
BLAST of Serine/threonine kinase vs. Ensembl Yeast
Match: DUN1 (Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259]) HSP 1 Score: 81.6481 bits (200), Expect = 1.126e-15 Identity = 75/285 (26.32%), Postives = 114/285 (40.00%), Query Frame = 2 Query: 9620 DRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIG------RSEFQCIQNISHRNIVEIFDAIAMP------DQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIM--TGKYNEILKLCG------FSNAVPKEDFGSRRHMGL---------TSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHG-----------HLKVN-FEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 D+Y K+L G Y+ + K T + K F R E + + H NIV + D+ P +YLVL EK+ L E I + + + + + + QL+ + YLHE + H DIKPENI++ T + N G V DFG + G T + APE+L + D+WS G++ ++CL G LK + + D I +S I L+L ER ++L+H WF Sbjct: 198 DKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVL--EKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWF 480 HSP 2 Score: 50.8322 bits (120), Expect = 3.766e-6 Identity = 49/212 (23.11%), Postives = 88/212 (41.51%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKIL--ISRRTNQS-------------FDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWF 12259 E + G L ++ ++ + + +QLL +++LH N++H +I+P IL I+RR N S +K+ +F G ++ +L PS + APE + + D+WS G++ ++ L P D + +L + F +P + S + N L +P++R N D L H WF Sbjct: 283 EKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCG-TPS-YVAPEVLTKKGYTSKVDLWSAGVILYVCLCG-FPPFSDQLGPPSLK-------EQILQAKYA-FYSP---YWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWF 480
BLAST of Serine/threonine kinase vs. Ensembl Yeast
Match: GIN4 (Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]) HSP 1 Score: 82.4185 bits (202), Expect = 1.157e-15 Identity = 68/221 (30.77%), Postives = 102/221 (46.15%), Query Frame = 2 Query: 9737 GIGRSEFQCIQNISHRNIVEIFDAIAM-PDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSP-FSAPELLKGEPIQ-FNSDMWSIGILTFLCLHGHLKVNFEGDQL-----------YNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIK 10357 GI R E ++ ++H N++ ++D D YLVL Y + L + + E + Q+I VSY H + H D+KPEN+++ KYN +K+ F A E G SP ++APE++ G P Q F SD+WS G++ F L G L + E + + S+D IS A IRK L + R+ + D L H K Sbjct: 77 GIER-EIIIMKLLNHPNVLRLYDVWETNTDLYLVLEY--AEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYN--IKIADFGMAA-LETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQK 291 HSP 2 Score: 58.151 bits (139), Expect = 2.968e-8 Identity = 52/226 (23.01%), Postives = 92/226 (40.71%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTH--KPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQ-----DPQTIYEMEHQTISSTPLVD 12325 E+ G L ++L+ R E + RQ++ + + H+ +VH +++P +L+ + N I G+ + G + E + H P I Y+ + SD+WS G++ F LL +LP E+ N TLLL V F P + S+ ++ + L P R L H ++ D ++I + + TPL + Sbjct: 111 EYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYN--IKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQG-----FASDVWSCGVILFALLTGRLPFDEEDG----------NIRTLLLKVQKGEFEMPSDDEI---SREAQDLIRKILTVDPERRIKTRDILKHPLLQKYPSIRDSKSIRGLPREDTYLTPLSE 316
BLAST of Serine/threonine kinase vs. Ensembl Yeast
Match: HSL1 (Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584]) HSP 1 Score: 82.4185 bits (202), Expect = 1.342e-15 Identity = 68/230 (29.57%), Postives = 107/230 (46.52%), Query Frame = 2 Query: 9722 EINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQ-YLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFS-------NAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFN-SDMWSIGILTFLCLHGHLKVNFEG---------DQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIK 10357 + N GI R E ++ ISH N++ +F+ + YLVL Y + G L +Y+ E + Q+++ VSY H +CH D+KPEN+++ K N +K+ F N + K GS +++PE++ G P SD+WS GI+ F L GHL N + Y SN +S+ A I K L++ +R+T+ + L H K Sbjct: 155 QTNPYGIER-EIVIMKLISHTNVMALFEVWENKSELYLVLEY--VDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLL-DKKNRRIKIADFGMAALELPNKLLKTSCGSPH-------YASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSN--LSSEARDLISKILVIDPEKRITTQEILKHPLIKK 371 HSP 2 Score: 52.7582 bits (125), Expect = 1.600e-6 Identity = 48/201 (23.88%), Postives = 80/201 (39.80%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTH--KPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQ 12265 E+V GG L L+++ E + +Q++ + + HS N+ H +++P +L+ ++ N+ I G+ + + + + H P I Y SD+WS GI+ F LL LP +D N LLL V ++ K M S +R + L P R L H K+ Sbjct: 194 EYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKK-NRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHG-----GPSDVWSCGIVLFALLTGHLPFNDD------------NIKKLLLKV-----QSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKK 371
BLAST of Serine/threonine kinase vs. Ensembl Nematostella
Match: OBSCURIN (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGL2]) HSP 1 Score: 108.997 bits (271), Expect = 3.629e-25 Identity = 78/268 (29.10%), Postives = 129/268 (48.13%), Query Frame = 2 Query: 9611 DVNDRYYTMK-KLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRS---EFQCIQNISHRNIVEIFDAIAMPDQY-LVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAV---PKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSN-------------DAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 D +YYT+K +L KG + + K T +F KF + + E + + I H+ ++ + DA P Q ++L+ E + G L E + + E+ V + Q+++ + ++H+ V HLD+KPENI++ + + +KL F A PKE+ + M T F APE+L + I +DMWSIG++ ++ L G F GD +N D IS+ A FI K L+LK R++ + + H W Sbjct: 15 DAITKYYTIKDELGKGRFGVVCKCVNKKTGKQFAAKFIKCSKPQDREDVIHEMEIMNTIRHKRLLRLADAFETPSQQEMILVMELVTGGELFEKVVEEEFISENDVTHYMKQILEGLEHMHKQEVLHLDLKPENIMIVKQDSRQIKLIDFGLARKYNPKENL---KVMFGTPEFVAPEVLTYDRITPATDMWSIGVIAYVLLSGL--SPFMGDNDAETLANVQTAEWDFDDPVFDDISDEAKDFIEKLLVLKATARISVAKCMEHPWL 277 HSP 2 Score: 53.5286 bits (127), Expect = 8.278e-7 Identity = 34/134 (25.37%), Postives = 68/134 (50.75%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYE-----SDIWSLGILSFLLLATQLPAIED 12055 E V GG L ++ SE V ++Q+L ++ +H V+H +++P I+I ++ ++ IKLI + +E+L +F PE+ + Y+ +D+WS+G+++++LL+ P + D Sbjct: 98 ELVTGGELFEKVVEEEFISENDVTHYMKQILEGLEHMHKQEVLHLDLKPENIMIVKQDSRQ--IKLI---DFGLARKYNPKENLKV----MFGTPEFVAPEVLTYDRITPATDMWSIGVIAYVLLSGLSPFMGD 222
BLAST of Serine/threonine kinase vs. Ensembl Nematostella
Match: EDO49547 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGL1]) HSP 1 Score: 105.145 bits (261), Expect = 1.608e-24 Identity = 74/247 (29.96%), Postives = 125/247 (50.61%), Query Frame = 2 Query: 9668 CQIVIEKSTQIEFIGKF--FEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSP-FSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDS-NDAISNSACVFIRKC--------------LLLKT-GERLTSSDSLSHEWF 10351 CQ V +TQ +F+ K ++ + EF + I +V + +A + YLVLI ++L G + ++++ + E ++I ++ A+ YLHE + HLDI+P NI++ G +KL F NA + + + +P F+APE+L EP+ +DMWS+GI+T+ L G L F GD N+D+ +A+ + C F+ + LL K +RL + +L+HEW Sbjct: 9 CQDV---TTQKDFVAKLIRYDEEDREDAVQEFSVHRGIDCNQVVRLHNAFLLR-SYLVLIMDRLDGEDVLKFMSSKTKVTEEDAALVIRGILNALCYLHELNIVHLDIRPANIMVQGSD---VKLIDFGNARKLKSRHGEVGVVVGNPSFTAPEVLSFEPVNMAADMWSVGIVTYALLSGQLP--FPGD---NDDAVEEAVKQARCTFVGRAFRSLTDHSKGFIEKLLYKIPSKRLEVAGALTHEWL 243 HSP 2 Score: 72.0182 bits (175), Expect = 3.629e-13 Identity = 52/193 (26.94%), Postives = 87/193 (45.08%), Query Frame = 2 Query: 11681 GGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWF 12259 G ++L + +++ +E +IR +L + +LH N+VH +I P I++ Q D+KLI N + + + + + PS F APE +D+WS+GI+++ LL+ QLP D +D V VK + FR+ + S+ F+ L K P+ R L H W Sbjct: 70 GEDVLKFMSSKTKVTEEDAALVIRGILNALCYLHELNIVHLDIRPANIMV-----QGSDVKLIDFGNARKLKSRHGEVGVVVGNPS-FTAPEVLSFEPVNMAADMWSVGIVTYALLSGQLPFPGD--NDDAVEEAVKQARCTFVG---RAFRS--------LTDHSKGFIEKLLYKIPSKRLEVAGALTHEWL 243
BLAST of Serine/threonine kinase vs. Ensembl Nematostella
Match: EDO43755 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXD2]) HSP 1 Score: 102.834 bits (255), Expect = 1.126e-23 Identity = 58/199 (29.15%), Postives = 104/199 (52.26%), Query Frame = 2 Query: 9611 DVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFE---INNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHG 10198 D++ Y +L +G Y+ + +EKST EF K + ++ + I R E ++ + H N+ DA P Y++ + E L G L +Y+ + E +HQ+++ V +LH+ + HLD+KP+N+++ G +K+ F +A + + F+APEL+ EP+ F +D WSIG++T++ L G Sbjct: 3 DIDQYYNIYAELGRGRYAVVKKCVEKSTGKEFAAKMVKKRMLDPVDIDR-EVTVLRMLKHPNLCIFLDAYDTPKNYII-VTELLAGGRLFDYLVVMDALTEKVAIGYMHQVVEGVQHLHDLNIVHLDLKPQNLLLDGGPLPKVKIIDFGSAHILSGSPVNHKVYGSPEFAAPELIMEEPLTFKTDTWSIGVITYVMLSG 199 HSP 2 Score: 54.6842 bits (130), Expect = 2.546e-7 Identity = 46/192 (23.96%), Postives = 82/192 (42.71%), Query Frame = 2 Query: 11579 DLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHK----PSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCC-VKNTNTLLLPVPHTHFRA 12139 +LC+ + Y P N I E + GG L L+ +E + + Q++ +Q LH N+VH +++P +L+ +K+I + + S HK P F APE E +++D WS+G++++++L+ P D +D C ++ N P+ HF A Sbjct: 63 NLCIFLDAYDTP-----------KNYIIVTELLAGGRLFDYLVVMDALTEKVAIGYMHQVVEGVQHLHDLNIVHLDLKPQNLLLDGGPLPK--VKIIDFGSAHILSG-----SPVNHKVYGSPE-FAAPELIMEEPLTFKTDTWSIGVITYVMLSGVSPFQADT---TDEMCERIRKAN---FSFPNKHFSA 229
BLAST of Serine/threonine kinase vs. Ensembl Nematostella
Match: EDO41242 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z6]) HSP 1 Score: 101.679 bits (252), Expect = 3.935e-23 Identity = 71/257 (27.63%), Postives = 128/257 (49.81%), Query Frame = 2 Query: 9626 YYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR---SEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI-LKLC--GFSNAVPKE-DFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH-----------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSH 10342 Y ++ + +GS+++ IE+ T +EF K + ++ E +++ H NIV ++ +I + + LI E + G SL + + Q +++ E Q R++ QL+ A+ YLH R+ H DIKP+N+++ N + +KL G + A+P + D S G F APE + EPI D+W+ G++ +L L G+ L G D +SN A + K +++ R+++ ++LSH Sbjct: 5 YDMLELIGEGSFAKVFRCIERKTGLEFAAKELRLTDVEDKEKIEQEIAVWKDLRHENIVSLYSSI-REGETVCLIMEYVAGGSLFDEVIQQTYYSEKQARLVTRQLLNALEYLHSRRIVHRDIKPDNLLLKRTGNNVTIKLADFGLAQALPNDTDVISCGASG-APMFLAPETVLEEPIGRAVDIWACGVIFYLLLVGYPPFWSNSDEQLLLSILRGQYTMPSPFWDNVSNDARDLVHKLIVVDPEARISAKEALSH 259 HSP 2 Score: 76.6406 bits (187), Expect = 1.324e-14 Identity = 57/200 (28.50%), Postives = 90/200 (45.00%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQD 12268 E+V GG+L ++ ++ YSE + RQLL +++LHS +VH +I+P +L+ +RT + IKL Q + + S +F APE E DIW+ G++ +LLL P S+SD LLL + + P S +R VH + P R +A L+H K++ Sbjct: 80 EYVAGGSLFDEVIQQTYYSEKQARLVTRQLLNALEYLHSRRIVHRDIKPDNLLL-KRTGNNVTIKLADFGLAQALPNDTDVISCGASGAPMFLAPETVLEEPIGRAVDIWACGVIFYLLLVGYPP----FWSNSD--------EQLLLSILRGQYTMPS-PFWDNVSNDARDLVHKLIVVDPEARISAKEALSHPALKEN 265
BLAST of Serine/threonine kinase vs. Ensembl Nematostella
Match: EDO42287 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1Z6]) HSP 1 Score: 100.908 bits (250), Expect = 6.288e-23 Identity = 70/231 (30.30%), Postives = 116/231 (50.22%), Query Frame = 2 Query: 9614 VNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRS---------EFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI-LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSACV 10276 V+ ++ ++ G ++ + EKS+ +EF KF + R E +++++H+ I+ + D ++ VLI E L G L E++++ E + + Q+I+A+ YLH+ + HLDIKPENI++ + + LKL F A R M T F APE++ E + F +DMWSIG+LT++ L G F GD D+N+ SN + V Sbjct: 13 VHHKFDIGDEIGSGQFAVVKKCSEKSSGLEFAAKFMKKRRSKALRRGVTLEQIIREATVLRSVAHQGIIYLHDIYETKMEF-VLILELLSGGELFEFLSEQDFLTEDEAVGFLIQVIRAIEYLHDLSIVHLDIKPENIVLKNRTRPLHLKLIDFGLARKISKGEPVREMMGTPEFVAPEIIDFEVVGFPTDMWSIGVLTYIMLSG--ASPFLGD-----DNNETFSNISHV 235 HSP 2 Score: 56.225 bits (134), Expect = 7.330e-8 Identity = 35/130 (26.92%), Postives = 69/130 (53.08%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKE-QESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIED 12055 E + GG L L + +E V + Q++ I++LH ++VH +I+P I++ RT + +KLI + + + +E + T + F APE + + +D+WS+G+L++++L+ P + D Sbjct: 98 ELLSGGELFEFLSEQDFLTEDEAVGFLIQVIRAIEYLHDLSIVHLDIKPENIVLKNRT-RPLHLKLIDFGLARKISKGEPVREMMGTPE---FVAPEIIDFEVVGFPTDMWSIGVLTYIMLSGASPFLGD 223
BLAST of Serine/threonine kinase vs. Ensembl Medaka
Match: spegb (striated muscle preferentially expressed protein kinase [Source:NCBI gene;Acc:101174306]) HSP 1 Score: 152.91 bits (385), Expect = 5.405e-36 Identity = 149/626 (23.80%), Postives = 267/626 (42.65%), Query Frame = 2 Query: 8564 LFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTIDDTVIPGSNGEREITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEG------WSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGE--YCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRV-------DAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRS--EFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVP-KEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQL-------YNEDSNDAISNSACV----FIRKCLLLKTGERLTSSDSLSHEWF 10351 +++ V N+ G + L+ I+PD D T + S + ITLSW PR +D P + Y+ ++ W++ + +K+ I L + Y R++ +T KPS ++ D P ++A + +K P + + + + + + +TW + Y++ + + ++ D GE + A +E +FI+ + PT + + + E +V ++ +P P+++W + + SS+ T + +D E SL++ D G Y+ A N G K L V D+ +++S+ + + D Y K++ +G++S + V K +++E++ KF S E + + H I+ DA + +++I EK L + T+ S ES VR I QL++ + YLH + HLDIKPEN++M +++ +++C F NAV K D G T F APE++ PI +D+W +G++ +LCL G E D+ YN +++ C FI K LL+ R S L H WF Sbjct: 735 VYKSVISNKIGKA--TCYAHLYVTDILPD------PPDGTPVIESITGKTITLSWKKPR---------RLDPSIDPSSLMYAIQQQALGSIQWTIIASGLKETTFTITTLSKGVRYTFRVLTITSKAFSKPSPATDPVQLLDR--GPYLQEAPAIIDK-----PDVVYVIEHQSVTISININHVNAAVTWKRKGVTLANKPSLYEMTMPDDDQHMLKLLKVKSTDVGEMTFVASNEYGSDSCTFIVEMAAPPTFETIMEDLDVCAGETPRFAVVVEGKPIPDILWFKGDNLLSESSHYTFVYDDNE---CSLVVLNAHPEDSGVYTCTARNLAGSVSCKAELTVHEAKHKEDSMEDEESILRKMRRLTDYYDIHKEIGRGAFSYVKRVTHKGSKMEYVAKFISTRAKKKTSSLREMNLLSRLDHERIIYFHDAFEKKNA-VIIITEKCHE-ELLDRFTRKSAILESDVRSCIRQLLEGLGYLHHQNIIHLDIKPENVLMADPHSDQIRICDFGNAVEIKPDEVQYCKYG-TPEFVAPEIVNQSPISKATDIWPVGVIAYLCLTGISPFAGENDRSSVLNIRNYNVAFEESMFADLCRESKGFIIK-LLVADRLRPDSQACLRHPWF 1329 HSP 2 Score: 98.5969 bits (244), Expect = 1.465e-19 Identity = 73/262 (27.86%), Postives = 127/262 (48.47%), Query Frame = 2 Query: 9626 YYTMKKLAKGSYSRCQIVIEKSTQIEFIGKF--FEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRH---MGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH---------------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 Y M + A+G + + E +T F+ K +E ++ E+ ++++ H I+ + +A P +YLVLI E G L +T+ + E V I Q++Q + YLH R+ HLDIKPENII+T + I+K+ F ++ ++ +G T + +PE+LKG+ + +D+WS+G++TF+ L G L + +LY +S SA +F++K L R + D ++ W Sbjct: 2371 YTFMDEKARGRFGVIRECRENATGNLFLAKIVPYEADSKQAVLQEYDILKSLHHDRIMALHEAYVTP-RYLVLISEYCSGKELLYSLTERFRYSEDDVVTYIVQVLQGLDYLHTRRILHLDIKPENIIVT--HMNIIKIIDFGSSQTYNPLFLKQFNPPIG-TLEYMSPEMLKGDVVGPPADIWSLGVVTFIMLSGRLPFMEINPQETEAKILAAKLDLSKLYQN-----VSQSASLFLKKILCSYPWARPSIKDCFNNSWL 2623 HSP 3 Score: 70.8626 bits (172), Expect = 4.010e-11 Identity = 88/438 (20.09%), Postives = 172/438 (39.27%), Query Frame = 2 Query: 5756 IKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAE----NMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKP--------------------LCAPVLTAEYSKGADVILSWTSVATT-DTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFET------VSNIIEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSL-SLEPGVSYMFRVIAFNDFGISEPS 6973 I +P++DI + ETV FE V W + + I M F C L + + E G Y +++ + S G+L ++ + PLFT++L +E++ N R +C++ P PK+ W+ ++L + + IL E +L+I+ +D G Y + N G + + + + + P S +++ P P+ + +G + +L T++ +N + + ST+ +K+ + + + S C + + V ++ G T V++I+ P P P I + +SW K + L P +MY+++ + W I+++ L + +++ +L GV Y FRV+ S+PS Sbjct: 447 IIRPVRDITAKAG-ETVLFECHVVGPKDTDVDWLADGKLIQPALLNCKMHFDGRKC----RLLLNSVHEDDSGTYMCKLSTAKEELTSCGKLKVV------------PSLEPLFTRRLDILEVMEGRNARFDCKISGTPPPKVTWSHFDQSL---VESEDIHILQEGGRHSLVISHVTSQDEGLYTIIAQNCHGEAESSSELYIQEPRPAISSQAKLEKMPSIPEEPEVPENEVERFTMPDFIKPLYDLDVIEGKEAVLKCKVAGLPYPTISWFHN---GRRIESTDDRKMTQFHDVHSLVIRSVCH--AHGGVYKSVISNKIGKATCYAHLYVTDILPDP--------PDGTPVIESITGKTITLSWK--KPRRLDPSIDPSSLMYAIQQQALGSIQWTIIASGLKETTFTITTLSKGVRYTFRVLTITSKAFSKPS 849 HSP 4 Score: 63.1586 bits (152), Expect = 9.020e-9 Identity = 90/408 (22.06%), Postives = 153/408 (37.50%), Query Frame = 2 Query: 5534 WLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRN-------EPETVKFEFEVEESGAKKAIW-FFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLM-LRSEISEQM----MESCCIA-------------PLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSV----ATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVS 6667 WL D KL+ + L+L V D+G Y K++ + KE + ++ L+ +F R E +F+ ++ + K W F+ +++E++ +Q +L I + G YTI N G S L + R IS Q M S P F K L D++++ + L C++ P P I W +G ++S + + D +L+I G Y + +N +G T A + VTD P D + +I E G + LSW + D +++Y I+ Q++L S W I L ETT+++++ L + R + I+ F S Sbjct: 478 WLADGKLIQPALLNCKMHFDGRKCRLLLNSVHEDDSGTYMCKLSTA-----------------KEELTSCGKLKVVPSLEPLFTRRLDILEVMEGRNARFDCKISGTPPPKVTWSHFDQSLVESEDIHILQEG--GRHSLVISHVTSQDEGLYTIIAQNCHGEAESSSELYIQEPRPAISSQAKLEKMPSIPEEPEVPENEVERFTMPDFIKPLYDLDVIEGKEAVLKCKVAGLPYPTISWFHNGRRIESTDDRKMTQFHDV---HSLVIRSVCHAHGGVYKSVISNKIGKATCYAHLYVTDILPDPPDGTPVI-----------ESITGKTITLSWKKPRRLDPSIDPSSLMYAIQ-QQALGSIQWTIIASGLKETTFTITT--LSKGVRYTFRVLTITSKAFSKPS 849 HSP 5 Score: 61.2326 bits (147), Expect = 3.597e-8 Identity = 41/136 (30.15%), Postives = 69/136 (50.74%), Query Frame = 2 Query: 11657 ITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSI----FKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIE 12052 + E+ G LL L R YSE VVT I Q+L + +LH+ ++H +I+P I+++ IK+I + Q + L P I + +PE + +DIWSLG+++F++L+ +LP +E Sbjct: 2441 VLISEYCSGKELLYSLTERFRYSEDDVVTYIVQVLQGLDYLHTRRILHLDIKPENIIVTHMNI----IKIIDFGSSQTYNPL----FLKQFNPPIGTLEYMSPEMLKGDVVGPPADIWSLGVVTFIMLSGRLPFME 2568 HSP 6 Score: 53.1434 bits (126), Expect = 9.171e-6 Identity = 47/188 (25.00%), Postives = 79/188 (42.02%), Query Frame = 2 Query: 10781 VTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSV-DNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRNIHSLKQALI 11341 VTL+C + GS ISW K+++ L D+R+ + G I+ T+ D G++ C+A +S + L +P +P + L+ W P + Y ++ R + N NW + V D Y + +L + R+ NK G PYS + V ++ K+ LI Sbjct: 2045 VTLSCLPA--GSPHPHISWQKDKKPLEIDARMNMISCPDGRQLLMIMQTTKKDAGVYECVATNPLASVSSSCTISLARLPNRPGTPEIPQKYNNTALVLWRPS-DTMAPCTYSLE-RKSEGDN---NWLIVATGVADCYYNVADLPAGGSFRFRVACVNKAGQGPYSNLSEVVHLDSFGMYKHKERLI 2225
BLAST of Serine/threonine kinase vs. Ensembl Medaka
Match: ENSORLT00000028146.1 (striated muscle enriched protein kinase [Source:NCBI gene;Acc:101164136]) HSP 1 Score: 142.124 bits (357), Expect = 1.280e-32 Identity = 138/593 (23.27%), Postives = 251/593 (42.33%), Query Frame = 2 Query: 8708 REITLSWS-PPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCL-AVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFI-----------IKNLEEDDFGEY--CALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVD------AHP--EKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNM--GIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSS--DSLSHEWFIKPGNN 10369 + ITLSW P R+ P L + V V + WSV +N+K+ + L + Y R++ T + KPS P+T+ +L L P+ K ++ + ++E + IT T N+ V +R + G Y + + + D G+ A ++ + + L+ + P + + + + E ++V ++ +P P+++W ++ + SS+ T + +D E YSL+I G Y+ A+N G K L V A P ++ S+ + + D Y K++ +G++S + V K + EF KF + E + + + I+ DA + +V++ +L L + + + + E ++R I Q+++ + YLH+ + HLDIKPENI+M + +++C F NA E+ T + APE++ P+ +D+W +G++T+LCL G E D+ + E + A F+ K L++ +RL S D L H WF P N Sbjct: 1134 KTITLSWKRPKRLDPSLDTSSLLYV----VQQQHLGSIQWSVVASNLKETTYTVTTLSKGVRYAFRVLTSTGKSLSKPS--------------PSTDLVQLLDRGPYLRKAPVIV---DKPDIVY--VVENQPTSITITLNHVHAVVTWKRRGVVLVNKLGTYEMSMPDDDQHTLKLLRVRNSDIGQLVVTASNQFGSDLCTLQLVMAVRPKFETIMEDVDVHIGETTRLAVVVEGKPDPDILWYKDDVLLSESSHFTFVYDDPE---YSLVILSAQPEHSGVYTCTAQNLAGSCSCKAELTVHTEQLEPAQPMEDEASILRKMRRLTDYYDIHKEIGRGAFSYVKKVTLKEGKAEFAAKFITARGKRKPLALREMDLLAELDNERILYFHDAFE--KKNIVILITELCHEELLDRMAKKTTVMELEIRKSIQQVLEGLRYLHQKSIAHLDIKPENILMASPRCDQIRICDFGNAQKLENLEEHYCKYGTPEYVAPEIVNQTPVSTTTDIWPVGVITYLCLTGVSPFAGENDRATALNIRNYNVAFEEGMFSGLCKEAKGFVIKLLVV---DRLRPSAVDCLRHPWFKSPTNK 1695 HSP 2 Score: 97.8265 bits (242), Expect = 2.651e-19 Identity = 75/278 (26.98%), Postives = 128/278 (46.04%), Query Frame = 2 Query: 9590 SVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKF--FEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNA-------VPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLK---------------VNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 S + G Y +++ A+G Y + E +T ++ K + N E++ ++++ I+ + +A P +YLVL+ E G L + + E V + Q++QAV YLH RV HLD+KP+NII+T ++K+ F +A + +++ G+ T + APE LK E + +DMW++G++T++ L G L F+ +LY +S SA F++K L R T+ D SH W Sbjct: 2902 STTLRQGVPQKPYTFLEEKARGRYGVVRECRENATGKMYMAKIIPYTQENKKDVLKEYEILKSLHSDKIMALHEAYVTP-RYLVLVAEYCTGKELLYTLIDRFRYSEDDVASYLVQILQAVEYLHNRRVLHLDLKPDNIIVTNL--NVVKVVDFGSAQSFNPLSLQQQESGAG-----TLEYMAPETLKREVVGPPADMWTVGVVTYIMLSGRLPFEDKEPHQVESKILMAKFDPSKLYPN-----VSQSASTFLKKMLSSYPWARPTTRDCFSHAWL 3166 HSP 3 Score: 58.9214 bits (141), Expect = 1.709e-7 Identity = 32/129 (24.81%), Postives = 70/129 (54.26%), Query Frame = 2 Query: 11657 ITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 + E+ G LL L+ R YSE V + + Q+L +++LH+ V+H +++P I++ TN + +K++ + Q + Q+ + + APE + +D+W++G++++++L+ +LP Sbjct: 2984 VLVAEYCTGKELLYTLIDRFRYSEDDVASYLVQILQAVEYLHNRRVLHLDLKPDNIIV---TNLNV-VKVVDFGSAQSFNPLSLQQQESGAGTLEYMAPETLKREVVGPPADMWTVGVVTYIMLSGRLP 3108 HSP 4 Score: 57.7658 bits (138), Expect = 4.086e-7 Identity = 59/225 (26.22%), Postives = 103/225 (45.78%), Query Frame = 2 Query: 6044 SEQMMESCC-IAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFT--LIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYG---FETVSNIIEIPIRANS 6700 S+Q + S AP+F KLKD +L E++ L+C P P+I W KD + LD+ + R+K L P+ LII+++ D+G Y C+ TN + TT + + S PK + P + Y+ A V+ W T + Y++E+ K NW + + + Y+++ LP ++ R +++ G + S + +P A+ Sbjct: 2509 SQQFIRSASDFAPVFHIKLKDHVLLEGESVTLSCLHAGSPHPEITWMKDRKPLDT--TDNRIK-LTSHPDGRQLLIISKSSHRDTGVYECVATNPIATITTSCTLSIA-SFPKRPGT----------PEVAQTYNNTALVL--WKPADTKPPCS--YSLER-KDEREANWVLVATGIADCYYNVTD--LPVGGTYKFRVSCVNKAGQGPYSCCSTPVTLPGTADG 2712
BLAST of Serine/threonine kinase vs. Ensembl Medaka
Match: ENSORLT00000032086.1 (striated muscle enriched protein kinase [Source:NCBI gene;Acc:101164136]) HSP 1 Score: 141.739 bits (356), Expect = 1.486e-32 Identity = 138/593 (23.27%), Postives = 251/593 (42.33%), Query Frame = 2 Query: 8708 REITLSWS-PPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCL-AVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFI-----------IKNLEEDDFGEY--CALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVD------AHP--EKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNM--GIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSS--DSLSHEWFIKPGNN 10369 + ITLSW P R+ P L + V V + WSV +N+K+ + L + Y R++ T + KPS P+T+ +L L P+ K ++ + ++E + IT T N+ V +R + G Y + + + D G+ A ++ + + L+ + P + + + + E ++V ++ +P P+++W ++ + SS+ T + +D E YSL+I G Y+ A+N G K L V A P ++ S+ + + D Y K++ +G++S + V K + EF KF + E + + + I+ DA + +V++ +L L + + + + E ++R I Q+++ + YLH+ + HLDIKPENI+M + +++C F NA E+ T + APE++ P+ +D+W +G++T+LCL G E D+ + E + A F+ K L++ +RL S D L H WF P N Sbjct: 1217 KTITLSWKRPKRLDPSLDTSSLLYV----VQQQHLGSIQWSVVASNLKETTYTVTTLSKGVRYAFRVLTSTGKSLSKPS--------------PSTDLVQLLDRGPYLRKAPVIV---DKPDIVY--VVENQPTSITITLNHVHAVVTWKRRGVVLVNKLGTYEMSMPDDDQHTLKLLRVRNSDIGQLVVTASNQFGSDLCTLQLVMAVRPKFETIMEDVDVHIGETTRLAVVVEGKPDPDILWYKDDVLLSESSHFTFVYDDPE---YSLVILSAQPEHSGVYTCTAQNLAGSCSCKAELTVHTEQLEPAQPMEDEASILRKMRRLTDYYDIHKEIGRGAFSYVKKVTLKEGKAEFAAKFITARGKRKPLALREMDLLAELDNERILYFHDAFE--KKNIVILITELCHEELLDRMAKKTTVMELEIRKSIQQVLEGLRYLHQKSIAHLDIKPENILMASPRCDQIRICDFGNAQKLENLEEHYCKYGTPEYVAPEIVNQTPVSTTTDIWPVGVITYLCLTGVSPFAGENDRATALNIRNYNVAFEEGMFSGLCKEAKGFVIKLLVV---DRLRPSAVDCLRHPWFKSPTNK 1778 HSP 2 Score: 97.8265 bits (242), Expect = 2.574e-19 Identity = 75/278 (26.98%), Postives = 128/278 (46.04%), Query Frame = 2 Query: 9590 SVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKF--FEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNA-------VPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLK---------------VNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 S + G Y +++ A+G Y + E +T ++ K + N E++ ++++ I+ + +A P +YLVL+ E G L + + E V + Q++QAV YLH RV HLD+KP+NII+T ++K+ F +A + +++ G+ T + APE LK E + +DMW++G++T++ L G L F+ +LY +S SA F++K L R T+ D SH W Sbjct: 2985 STTLRQGVPQKPYTFLEEKARGRYGVVRECRENATGKMYMAKIIPYTQENKKDVLKEYEILKSLHSDKIMALHEAYVTP-RYLVLVAEYCTGKELLYTLIDRFRYSEDDVASYLVQILQAVEYLHNRRVLHLDLKPDNIIVTNL--NVVKVVDFGSAQSFNPLSLQQQESGAG-----TLEYMAPETLKREVVGPPADMWTVGVVTYIMLSGRLPFEDKEPHQVESKILMAKFDPSKLYPN-----VSQSASTFLKKMLSSYPWARPTTRDCFSHAWL 3249 HSP 3 Score: 58.9214 bits (141), Expect = 1.615e-7 Identity = 32/129 (24.81%), Postives = 70/129 (54.26%), Query Frame = 2 Query: 11657 ITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 + E+ G LL L+ R YSE V + + Q+L +++LH+ V+H +++P I++ TN + +K++ + Q + Q+ + + APE + +D+W++G++++++L+ +LP Sbjct: 3067 VLVAEYCTGKELLYTLIDRFRYSEDDVASYLVQILQAVEYLHNRRVLHLDLKPDNIIV---TNLNV-VKVVDFGSAQSFNPLSLQQQESGAGTLEYMAPETLKREVVGPPADMWTVGVVTYIMLSGRLP 3191 HSP 4 Score: 57.7658 bits (138), Expect = 3.641e-7 Identity = 59/225 (26.22%), Postives = 103/225 (45.78%), Query Frame = 2 Query: 6044 SEQMMESCC-IAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFT--LIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYG---FETVSNIIEIPIRANS 6700 S+Q + S AP+F KLKD +L E++ L+C P P+I W KD + LD+ + R+K L P+ LII+++ D+G Y C+ TN + TT + + S PK + P + Y+ A V+ W T + Y++E+ K NW + + + Y+++ LP ++ R +++ G + S + +P A+ Sbjct: 2592 SQQFIRSASDFAPVFHIKLKDHVLLEGESVTLSCLHAGSPHPEITWMKDRKPLDT--TDNRIK-LTSHPDGRQLLIISKSSHRDTGVYECVATNPIATITTSCTLSIA-SFPKRPGT----------PEVAQTYNNTALVL--WKPADTKPPCS--YSLER-KDEREANWVLVATGIADCYYNVTD--LPVGGTYKFRVSCVNKAGQGPYSCCSTPVTLPGTADG 2795
BLAST of Serine/threonine kinase vs. Ensembl Medaka
Match: ENSORLT00000002709.2 (striated muscle enriched protein kinase [Source:NCBI gene;Acc:101164136]) HSP 1 Score: 141.739 bits (356), Expect = 1.716e-32 Identity = 138/593 (23.27%), Postives = 251/593 (42.33%), Query Frame = 2 Query: 8708 REITLSWS-PPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCL-AVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFI-----------IKNLEEDDFGEY--CALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIF-SSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVD------AHP--EKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNM--GIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQ-----------LYNEDSNDAISNSACVFIRKCLLLKTGERLTSS--DSLSHEWFIKPGNN 10369 + ITLSW P R+ P L + V V + WSV +N+K+ + L + Y R++ T + KPS P+T+ +L L P+ K ++ + ++E + IT T N+ V +R + G Y + + + D G+ A ++ + + L+ + P + + + + E ++V ++ +P P+++W ++ + SS+ T + +D E YSL+I G Y+ A+N G K L V A P ++ S+ + + D Y K++ +G++S + V K + EF KF + E + + + I+ DA + +V++ +L L + + + + E ++R I Q+++ + YLH+ + HLDIKPENI+M + +++C F NA E+ T + APE++ P+ +D+W +G++T+LCL G E D+ + E + A F+ K L++ +RL S D L H WF P N Sbjct: 1125 KTITLSWKRPKRLDPSLDTSSLLYV----VQQQHLGSIQWSVVASNLKETTYTVTTLSKGVRYAFRVLTSTGKSLSKPS--------------PSTDLVQLLDRGPYLRKAPVIV---DKPDIVY--VVENQPTSITITLNHVHAVVTWKRRGVVLVNKLGTYEMSMPDDDQHTLKLLRVRNSDIGQLVVTASNQFGSDLCTLQLVMAVRPKFETIMEDVDVHIGETTRLAVVVEGKPDPDILWYKDDVLLSESSHFTFVYDDPE---YSLVILSAQPEHSGVYTCTAQNLAGSCSCKAELTVHTEQLEPAQPMEDEASILRKMRRLTDYYDIHKEIGRGAFSYVKKVTLKEGKAEFAAKFITARGKRKPLALREMDLLAELDNERILYFHDAFE--KKNIVILITELCHEELLDRMAKKTTVMELEIRKSIQQVLEGLRYLHQKSIAHLDIKPENILMASPRCDQIRICDFGNAQKLENLEEHYCKYGTPEYVAPEIVNQTPVSTTTDIWPVGVITYLCLTGVSPFAGENDRATALNIRNYNVAFEEGMFSGLCKEAKGFVIKLLVV---DRLRPSAVDCLRHPWFKSPTNK 1686 HSP 2 Score: 97.8265 bits (242), Expect = 2.695e-19 Identity = 75/278 (26.98%), Postives = 128/278 (46.04%), Query Frame = 2 Query: 9590 SVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKF--FEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNA-------VPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLK---------------VNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWF 10351 S + G Y +++ A+G Y + E +T ++ K + N E++ ++++ I+ + +A P +YLVL+ E G L + + E V + Q++QAV YLH RV HLD+KP+NII+T ++K+ F +A + +++ G+ T + APE LK E + +DMW++G++T++ L G L F+ +LY +S SA F++K L R T+ D SH W Sbjct: 2893 STTLRQGVPQKPYTFLEEKARGRYGVVRECRENATGKMYMAKIIPYTQENKKDVLKEYEILKSLHSDKIMALHEAYVTP-RYLVLVAEYCTGKELLYTLIDRFRYSEDDVASYLVQILQAVEYLHNRRVLHLDLKPDNIIVTNL--NVVKVVDFGSAQSFNPLSLQQQESGAG-----TLEYMAPETLKREVVGPPADMWTVGVVTYIMLSGRLPFEDKEPHQVESKILMAKFDPSKLYPN-----VSQSASTFLKKMLSSYPWARPTTRDCFSHAWL 3157 HSP 3 Score: 58.9214 bits (141), Expect = 1.843e-7 Identity = 32/129 (24.81%), Postives = 70/129 (54.26%), Query Frame = 2 Query: 11657 ITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 + E+ G LL L+ R YSE V + + Q+L +++LH+ V+H +++P I++ TN + +K++ + Q + Q+ + + APE + +D+W++G++++++L+ +LP Sbjct: 2975 VLVAEYCTGKELLYTLIDRFRYSEDDVASYLVQILQAVEYLHNRRVLHLDLKPDNIIV---TNLNV-VKVVDFGSAQSFNPLSLQQQESGAGTLEYMAPETLKREVVGPPADMWTVGVVTYIMLSGRLP 3099 HSP 4 Score: 57.7658 bits (138), Expect = 3.757e-7 Identity = 59/225 (26.22%), Postives = 103/225 (45.78%), Query Frame = 2 Query: 6044 SEQMMESCC-IAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFT--LIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYG---FETVSNIIEIPIRANS 6700 S+Q + S AP+F KLKD +L E++ L+C P P+I W KD + LD+ + R+K L P+ LII+++ D+G Y C+ TN + TT + + S PK + P + Y+ A V+ W T + Y++E+ K NW + + + Y+++ LP ++ R +++ G + S + +P A+ Sbjct: 2500 SQQFIRSASDFAPVFHIKLKDHVLLEGESVTLSCLHAGSPHPEITWMKDRKPLDT--TDNRIK-LTSHPDGRQLLIISKSSHRDTGVYECVATNPIATITTSCTLSIA-SFPKRPGT----------PEVAQTYNNTALVL--WKPADTKPPCS--YSLER-KDEREANWVLVATGIADCYYNVTD--LPVGGTYKFRVSCVNKAGQGPYSCCSTPVTLPGTADG 2703
BLAST of Serine/threonine kinase vs. Ensembl Medaka
Match: dapk2b (death associated protein kinase 2 [Source:NCBI gene;Acc:101165975]) HSP 1 Score: 116.316 bits (290), Expect = 6.945e-27 Identity = 85/287 (29.62%), Postives = 136/287 (47.39%), Query Frame = 2 Query: 9611 DVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFE-----INNMGIGRSEFQ----CIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEI--LKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGH---------------LKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYI 10393 +V D Y ++L G ++ + EKS+ EF KF + + G+ R E + +Q + H NIV + D +VLI E + G L +++ Q E + I Q++ V YLH R+ H D+KPENI++ + + +KL F A E +++ T F APE++ E + +DMWSIG++T++ L G VN+E ++ED S A FIR+ L T +R+ D+L+H W IKP N+ A + + Sbjct: 13 NVEDFYEMGEQLGSGQFAVVKRCKEKSSGTEFAAKFIKKRISRASRRGVKREEIEREVGILQQLQHPNIVALHDVYENRTD-VVLIMELVSGGELFDFLAQKESLSEEEATQFIKQILDGVQYLHSKRIAHFDLKPENIMLLDRNASLPRIKLIDFGLAHQIEAGADFKNIFGTPEFVAPEIVNYEQLGLEADMWSIGVITYILLSGASPFLGDTKQETLGNISAVNYE----FDEDFFGNTSELAKSFIRQLLEKDTRKRMAIEDALNHPW-IKPLNSRQAMVKRL 293 HSP 2 Score: 68.1662 bits (165), Expect = 6.402e-11 Identity = 52/203 (25.62%), Postives = 88/203 (43.35%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRY-----ESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFK 12262 E V GG L L + SE I+Q+L +Q+LHS + H +++P I++ R IKLI G + E+ K +IF PE+ I Y E+D+WS+G+++++LL+ P + D ++ + N + + F S+ ++ F+ L+K R + L H W K Sbjct: 99 ELVSGGELFDFLAQKESLSEEEATQFIKQILDGVQYLHSKRIAHFDLKPENIMLLDRNASLPRIKLIDF------GLAHQIEAGADFK-NIFGTPEFVAPEIVNYEQLGLEADMWSIGVITYILLSGASPFLGDTKQET-----LGNISAVNYEFDEDFF--------GNTSELAKSFIRQLLEKDTRKRMAIEDALNHPWIK 281
BLAST of Serine/threonine kinase vs. Planmine SMEST
Match: SMESG000022977.1 (SMESG000022977.1) HSP 1 Score: 8185.48 bits (21238), Expect = 0.000e+0 Identity = 4094/4094 (100.00%), Postives = 4094/4094 (100.00%), Query Frame = 2 Query: 62 MIFQLLWSLIGIFSILGYLFLWLQQRLERDNAILSKPRSSNLSDEEYLNNLIINSPSVSSISQKNDSSVDPEFITTDLDDDNEAVENLDTSQYSDVTDLDELEDTNMSDSLERNKLHYERSFDATIEDVASDFQSNDDLLSFIKTCKPIPGTKYYANCTIKCKENSELIKTTEGSAVSIEDADNLDYWISFSDDLPIPLSIVPRCCLSNSPNAENPDSESRKRNPRESFREDILQISNKNQESTMKRKYALADLIECDREYCATXXXXXXXXXXXXXTENEFGVEIDSLFEEVCKLIVELVEFHENLILPELSSCVMIPIRVANILKNQKLQFYRYSEFQSQWXXXXXXXXXXXXXXXFVKNVNTIEKSKFSVLSFNDLMLKVENKLPQYNLFLFDIIRYTGRIDGEVNDLQKAITVFQKIRRRNQEKVYLSKLIEKTNINISNERFIRVTNQVMISETQIMSKSYENLQFIREEMCSLILLKNYLLCVSDLSQPTDRKIMNLDYTKIYTKENYERQNELIIWSKMNKLEFRIFILYFPNKVSKLGWLRDLTKRLKKKGIDEIFVSSTEYDIQYKQYLGKNQRLVATEMESIGLESASLENECSSISDQIEDLTSMADSITDVRFESAILDMPSSMTSGSYKTAPETFKSTMDKASRPISGISQDSVSTLDGVRTPFSDXXXXXXXXXXXXXXXXXXXXXXDFVWSLKLVNFDPILHDIVWSLVGKTLDLTSQNSSIKIEEQNNKVYECQLKRQKLTKLESGQLSCKIIDKINGSLIVSKIVNVFISPPCISTELSCELTEVTVLENNPITFQLISGTNCLKNSFLNHITWYKDNERLVKEEGRIKTFXXXXXXXXXXXXEKASISDAGIYTISCAPNSEIFIKNVSNISILLLVERQKKTIYKTASLENQPIIEDSHTHAISPLKELVNIGNTFDGSDLYSNAVSSTTQLSEYDSRQLVGYFECEIEEIDLKIGELLSLQIKPISIPLSTLNLGSWYLNSKKLNLTELNGNEDISESQVSINIPGIVKDFSGVLQFRIETPMKIYSPEVVIKIRVGNLKSKPNGYFFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHLKGQPCLKWRAATVPEFCDSCVSGILPDYKVEYRNGRLSPWKIYQENIMQNETYLTQKIIDDAQEFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSPSVEKVKTIIKYDQLKQAEIESISKDGLSLKWSQWVPDQINKYIIQRKNSFSQDWEQIHSTIFGENCFVEMILSENFSRQLRILSLDDNKTELHDGYNILYIPSKDECIPTIPENLQVNDLTNYHEIFWSESKSIEIVDSPITYSLQSKVNNQFWFTITEKLDKCFYTNTRIDKYGVTGYRVLARNSIGSSPFSMEVFTKSLINILSNEQIIKSLRYFVINPREIEIKWHLCESIFDSGITTEDLSFQIEKKTVKEGSDWVPISNIVERNSILISITFEDENLFRIQPFYRDEKLSASRIFRMYVSKDLLVPDMSFTRPNLVIDSVTSCAIEWPEPELQSGFSPDGIEICVPSVLLVDLQYEIQFVVVDPIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTIDDTVIPGSNGEREITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQIVKLMTYPEEMVPNFPSDMKNAIETLLIDSRPKVIFNSSLSNPEGSVXXXXXXXXXXXXXXXRDGINYERCDTPNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRNIHSLKQALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPLVDFVNANL 12343 MIFQLLWSLIGIFSILGYLFLWLQQRLERDNAILSKPRSSNLSDEEYLNNLIINSPSVSSISQKNDSSVDPEFITTDLDDDNEAVENLDTSQYSDVTDLDELEDTNMSDSLERNKLHYERSFDATIEDVASDFQSNDDLLSFIKTCKPIPGTKYYANCTIKCKENSELIKTTEGSAVSIEDADNLDYWISFSDDLPIPLSIVPRCCLSNSPNAENPDSESRKRNPRESFREDILQISNKNQESTMKRKYALADLIECDREYCATLKLIKDILKSLDKTENEFGVEIDSLFEEVCKLIVELVEFHENLILPELSSCVMIPIRVANILKNQKLQFYRYSEFQSQWKKLKILLDISKKKYIFVKNVNTIEKSKFSVLSFNDLMLKVENKLPQYNLFLFDIIRYTGRIDGEVNDLQKAITVFQKIRRRNQEKVYLSKLIEKTNINISNERFIRVTNQVMISETQIMSKSYENLQFIREEMCSLILLKNYLLCVSDLSQPTDRKIMNLDYTKIYTKENYERQNELIIWSKMNKLEFRIFILYFPNKVSKLGWLRDLTKRLKKKGIDEIFVSSTEYDIQYKQYLGKNQRLVATEMESIGLESASLENECSSISDQIEDLTSMADSITDVRFESAILDMPSSMTSGSYKTAPETFKSTMDKASRPISGISQDSVSTLDGVRTPFSDEELIKSVLIISEIEEINISEGSDFVWSLKLVNFDPILHDIVWSLVGKTLDLTSQNSSIKIEEQNNKVYECQLKRQKLTKLESGQLSCKIIDKINGSLIVSKIVNVFISPPCISTELSCELTEVTVLENNPITFQLISGTNCLKNSFLNHITWYKDNERLVKEEGRIKTFINSSNNKISLIIEKASISDAGIYTISCAPNSEIFIKNVSNISILLLVERQKKTIYKTASLENQPIIEDSHTHAISPLKELVNIGNTFDGSDLYSNAVSSTTQLSEYDSRQLVGYFECEIEEIDLKIGELLSLQIKPISIPLSTLNLGSWYLNSKKLNLTELNGNEDISESQVSINIPGIVKDFSGVLQFRIETPMKIYSPEVVIKIRVGNLKSKPNGYFFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHLKGQPCLKWRAATVPEFCDSCVSGILPDYKVEYRNGRLSPWKIYQENIMQNETYLTQKIIDDAQEFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSPSVEKVKTIIKYDQLKQAEIESISKDGLSLKWSQWVPDQINKYIIQRKNSFSQDWEQIHSTIFGENCFVEMILSENFSRQLRILSLDDNKTELHDGYNILYIPSKDECIPTIPENLQVNDLTNYHEIFWSESKSIEIVDSPITYSLQSKVNNQFWFTITEKLDKCFYTNTRIDKYGVTGYRVLARNSIGSSPFSMEVFTKSLINILSNEQIIKSLRYFVINPREIEIKWHLCESIFDSGITTEDLSFQIEKKTVKEGSDWVPISNIVERNSILISITFEDENLFRIQPFYRDEKLSASRIFRMYVSKDLLVPDMSFTRPNLVIDSVTSCAIEWPEPELQSGFSPDGIEICVPSVLLVDLQYEIQFVVVDPIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTIDDTVIPGSNGEREITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQIVKLMTYPEEMVPNFPSDMKNAIETLLIDSRPKVIFNSSLSNPEGSVSPPISQLSSRASSSSRDGINYERCDTPNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRNIHSLKQALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPLVDFVNANL Sbjct: 1 MIFQLLWSLIGIFSILGYLFLWLQQRLERDNAILSKPRSSNLSDEEYLNNLIINSPSVSSISQKNDSSVDPEFITTDLDDDNEAVENLDTSQYSDVTDLDELEDTNMSDSLERNKLHYERSFDATIEDVASDFQSNDDLLSFIKTCKPIPGTKYYANCTIKCKENSELIKTTEGSAVSIEDADNLDYWISFSDDLPIPLSIVPRCCLSNSPNAENPDSESRKRNPRESFREDILQISNKNQESTMKRKYALADLIECDREYCATLKLIKDILKSLDKTENEFGVEIDSLFEEVCKLIVELVEFHENLILPELSSCVMIPIRVANILKNQKLQFYRYSEFQSQWKKLKILLDISKKKYIFVKNVNTIEKSKFSVLSFNDLMLKVENKLPQYNLFLFDIIRYTGRIDGEVNDLQKAITVFQKIRRRNQEKVYLSKLIEKTNINISNERFIRVTNQVMISETQIMSKSYENLQFIREEMCSLILLKNYLLCVSDLSQPTDRKIMNLDYTKIYTKENYERQNELIIWSKMNKLEFRIFILYFPNKVSKLGWLRDLTKRLKKKGIDEIFVSSTEYDIQYKQYLGKNQRLVATEMESIGLESASLENECSSISDQIEDLTSMADSITDVRFESAILDMPSSMTSGSYKTAPETFKSTMDKASRPISGISQDSVSTLDGVRTPFSDEELIKSVLIISEIEEINISEGSDFVWSLKLVNFDPILHDIVWSLVGKTLDLTSQNSSIKIEEQNNKVYECQLKRQKLTKLESGQLSCKIIDKINGSLIVSKIVNVFISPPCISTELSCELTEVTVLENNPITFQLISGTNCLKNSFLNHITWYKDNERLVKEEGRIKTFINSSNNKISLIIEKASISDAGIYTISCAPNSEIFIKNVSNISILLLVERQKKTIYKTASLENQPIIEDSHTHAISPLKELVNIGNTFDGSDLYSNAVSSTTQLSEYDSRQLVGYFECEIEEIDLKIGELLSLQIKPISIPLSTLNLGSWYLNSKKLNLTELNGNEDISESQVSINIPGIVKDFSGVLQFRIETPMKIYSPEVVIKIRVGNLKSKPNGYFFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHLKGQPCLKWRAATVPEFCDSCVSGILPDYKVEYRNGRLSPWKIYQENIMQNETYLTQKIIDDAQEFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSPSVEKVKTIIKYDQLKQAEIESISKDGLSLKWSQWVPDQINKYIIQRKNSFSQDWEQIHSTIFGENCFVEMILSENFSRQLRILSLDDNKTELHDGYNILYIPSKDECIPTIPENLQVNDLTNYHEIFWSESKSIEIVDSPITYSLQSKVNNQFWFTITEKLDKCFYTNTRIDKYGVTGYRVLARNSIGSSPFSMEVFTKSLINILSNEQIIKSLRYFVINPREIEIKWHLCESIFDSGITTEDLSFQIEKKTVKEGSDWVPISNIVERNSILISITFEDENLFRIQPFYRDEKLSASRIFRMYVSKDLLVPDMSFTRPNLVIDSVTSCAIEWPEPELQSGFSPDGIEICVPSVLLVDLQYEIQFVVVDPIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTIDDTVIPGSNGEREITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQIVKLMTYPEEMVPNFPSDMKNAIETLLIDSRPKVIFNSSLSNPEGSVSPPISQLSSRASSSSRDGINYERCDTPNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRNIHSLKQALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPLVDFVNANL 4094
BLAST of Serine/threonine kinase vs. Planmine SMEST
Match: SMESG000022977.1 (SMESG000022977.1) HSP 1 Score: 7975.16 bits (20692), Expect = 0.000e+0 Identity = 3988/3988 (100.00%), Postives = 3988/3988 (100.00%), Query Frame = 2 Query: 380 MSDSLERNKLHYERSFDATIEDVASDFQSNDDLLSFIKTCKPIPGTKYYANCTIKCKENSELIKTTEGSAVSIEDADNLDYWISFSDDLPIPLSIVPRCCLSNSPNAENPDSESRKRNPRESFREDILQISNKNQESTMKRKYALADLIECDREYCATXXXXXXXXXXXXXTENEFGVEIDSLFEEVCKLIVELVEFHENLILPELSSCVMIPIRVANILKNQKLQFYRYSEFQSQWXXXXXXXXXXXXXXXFVKNVNTIEKSKFSVLSFNDLMLKVENKLPQYNLFLFDIIRYTGRIDGEVNDLQKAITVFQKIRRRNQEKVYLSKLIEKTNINISNERFIRVTNQVMISETQIMSKSYENLQFIREEMCSLILLKNYLLCVSDLSQPTDRKIMNLDYTKIYTKENYERQNELIIWSKMNKLEFRIFILYFPNKVSKLGWLRDLTKRLKKKGIDEIFVSSTEYDIQYKQYLGKNQRLVATEMESIGLESASLENECSSISDQIEDLTSMADSITDVRFESAILDMPSSMTSGSYKTAPETFKSTMDKASRPISGISQDSVSTLDGVRTPFSDXXXXXXXXXXXXXXXXXXXXXXDFVWSLKLVNFDPILHDIVWSLVGKTLDLTSQNSSIKIEEQNNKVYECQLKRQKLTKLESGQLSCKIIDKINGSLIVSKIVNVFISPPCISTELSCELTEVTVLENNPITFQLISGTNCLKNSFLNHITWYKDNERLVKEEGRIKTFXXXXXXXXXXXXEKASISDAGIYTISCAPNSEIFIKNVSNISILLLVERQKKTIYKTASLENQPIIEDSHTHAISPLKELVNIGNTFDGSDLYSNAVSSTTQLSEYDSRQLVGYFECEIEEIDLKIGELLSLQIKPISIPLSTLNLGSWYLNSKKLNLTELNGNEDISESQVSINIPGIVKDFSGVLQFRIETPMKIYSPEVVIKIRVGNLKSKPNGYFFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHLKGQPCLKWRAATVPEFCDSCVSGILPDYKVEYRNGRLSPWKIYQENIMQNETYLTQKIIDDAQEFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSPSVEKVKTIIKYDQLKQAEIESISKDGLSLKWSQWVPDQINKYIIQRKNSFSQDWEQIHSTIFGENCFVEMILSENFSRQLRILSLDDNKTELHDGYNILYIPSKDECIPTIPENLQVNDLTNYHEIFWSESKSIEIVDSPITYSLQSKVNNQFWFTITEKLDKCFYTNTRIDKYGVTGYRVLARNSIGSSPFSMEVFTKSLINILSNEQIIKSLRYFVINPREIEIKWHLCESIFDSGITTEDLSFQIEKKTVKEGSDWVPISNIVERNSILISITFEDENLFRIQPFYRDEKLSASRIFRMYVSKDLLVPDMSFTRPNLVIDSVTSCAIEWPEPELQSGFSPDGIEICVPSVLLVDLQYEIQFVVVDPIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTIDDTVIPGSNGEREITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQIVKLMTYPEEMVPNFPSDMKNAIETLLIDSRPKVIFNSSLSNPEGSVXXXXXXXXXXXXXXXRDGINYERCDTPNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRNIHSLKQALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPLVDFVNANL 12343 MSDSLERNKLHYERSFDATIEDVASDFQSNDDLLSFIKTCKPIPGTKYYANCTIKCKENSELIKTTEGSAVSIEDADNLDYWISFSDDLPIPLSIVPRCCLSNSPNAENPDSESRKRNPRESFREDILQISNKNQESTMKRKYALADLIECDREYCATLKLIKDILKSLDKTENEFGVEIDSLFEEVCKLIVELVEFHENLILPELSSCVMIPIRVANILKNQKLQFYRYSEFQSQWKKLKILLDISKKKYIFVKNVNTIEKSKFSVLSFNDLMLKVENKLPQYNLFLFDIIRYTGRIDGEVNDLQKAITVFQKIRRRNQEKVYLSKLIEKTNINISNERFIRVTNQVMISETQIMSKSYENLQFIREEMCSLILLKNYLLCVSDLSQPTDRKIMNLDYTKIYTKENYERQNELIIWSKMNKLEFRIFILYFPNKVSKLGWLRDLTKRLKKKGIDEIFVSSTEYDIQYKQYLGKNQRLVATEMESIGLESASLENECSSISDQIEDLTSMADSITDVRFESAILDMPSSMTSGSYKTAPETFKSTMDKASRPISGISQDSVSTLDGVRTPFSDEELIKSVLIISEIEEINISEGSDFVWSLKLVNFDPILHDIVWSLVGKTLDLTSQNSSIKIEEQNNKVYECQLKRQKLTKLESGQLSCKIIDKINGSLIVSKIVNVFISPPCISTELSCELTEVTVLENNPITFQLISGTNCLKNSFLNHITWYKDNERLVKEEGRIKTFINSSNNKISLIIEKASISDAGIYTISCAPNSEIFIKNVSNISILLLVERQKKTIYKTASLENQPIIEDSHTHAISPLKELVNIGNTFDGSDLYSNAVSSTTQLSEYDSRQLVGYFECEIEEIDLKIGELLSLQIKPISIPLSTLNLGSWYLNSKKLNLTELNGNEDISESQVSINIPGIVKDFSGVLQFRIETPMKIYSPEVVIKIRVGNLKSKPNGYFFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHLKGQPCLKWRAATVPEFCDSCVSGILPDYKVEYRNGRLSPWKIYQENIMQNETYLTQKIIDDAQEFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSPSVEKVKTIIKYDQLKQAEIESISKDGLSLKWSQWVPDQINKYIIQRKNSFSQDWEQIHSTIFGENCFVEMILSENFSRQLRILSLDDNKTELHDGYNILYIPSKDECIPTIPENLQVNDLTNYHEIFWSESKSIEIVDSPITYSLQSKVNNQFWFTITEKLDKCFYTNTRIDKYGVTGYRVLARNSIGSSPFSMEVFTKSLINILSNEQIIKSLRYFVINPREIEIKWHLCESIFDSGITTEDLSFQIEKKTVKEGSDWVPISNIVERNSILISITFEDENLFRIQPFYRDEKLSASRIFRMYVSKDLLVPDMSFTRPNLVIDSVTSCAIEWPEPELQSGFSPDGIEICVPSVLLVDLQYEIQFVVVDPIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTIDDTVIPGSNGEREITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQIVKLMTYPEEMVPNFPSDMKNAIETLLIDSRPKVIFNSSLSNPEGSVSPPISQLSSRASSSSRDGINYERCDTPNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRNIHSLKQALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPLVDFVNANL Sbjct: 1 MSDSLERNKLHYERSFDATIEDVASDFQSNDDLLSFIKTCKPIPGTKYYANCTIKCKENSELIKTTEGSAVSIEDADNLDYWISFSDDLPIPLSIVPRCCLSNSPNAENPDSESRKRNPRESFREDILQISNKNQESTMKRKYALADLIECDREYCATLKLIKDILKSLDKTENEFGVEIDSLFEEVCKLIVELVEFHENLILPELSSCVMIPIRVANILKNQKLQFYRYSEFQSQWKKLKILLDISKKKYIFVKNVNTIEKSKFSVLSFNDLMLKVENKLPQYNLFLFDIIRYTGRIDGEVNDLQKAITVFQKIRRRNQEKVYLSKLIEKTNINISNERFIRVTNQVMISETQIMSKSYENLQFIREEMCSLILLKNYLLCVSDLSQPTDRKIMNLDYTKIYTKENYERQNELIIWSKMNKLEFRIFILYFPNKVSKLGWLRDLTKRLKKKGIDEIFVSSTEYDIQYKQYLGKNQRLVATEMESIGLESASLENECSSISDQIEDLTSMADSITDVRFESAILDMPSSMTSGSYKTAPETFKSTMDKASRPISGISQDSVSTLDGVRTPFSDEELIKSVLIISEIEEINISEGSDFVWSLKLVNFDPILHDIVWSLVGKTLDLTSQNSSIKIEEQNNKVYECQLKRQKLTKLESGQLSCKIIDKINGSLIVSKIVNVFISPPCISTELSCELTEVTVLENNPITFQLISGTNCLKNSFLNHITWYKDNERLVKEEGRIKTFINSSNNKISLIIEKASISDAGIYTISCAPNSEIFIKNVSNISILLLVERQKKTIYKTASLENQPIIEDSHTHAISPLKELVNIGNTFDGSDLYSNAVSSTTQLSEYDSRQLVGYFECEIEEIDLKIGELLSLQIKPISIPLSTLNLGSWYLNSKKLNLTELNGNEDISESQVSINIPGIVKDFSGVLQFRIETPMKIYSPEVVIKIRVGNLKSKPNGYFFTNLKQIETISGENLHVQFKAYNIVLDTLKKGSWFVNNELLDFKKWNGSVNVSESQVEINFPKSTNELSGIWQFRIDKPMKLFSPEISVNVLAKEVAPLSTGFLDCEIEEIDLKIGETLSLTLNAKDIPIMTLKNGGWFLNSEPIHAVKFRGNEVIEENKVKIVIPNVTKEFSGLLQYRIVKPVELYSPEIIIKIRGSLIKQTPKIEEEKFESNLILELHNVSLNISENERILLEAKIISGNINSYKTPPQWFWNDEAVKNINCKKDFTSNLAQLEIAHCQLSDSGQYKICFNPLEASKCGKVTGLFLVSIAPIKKNLKPIDSNIETCPGESVTLCVDVEGFSKKDIKWKVLEDDLKQDKILQEKRITQKFNNNLSFLLIDSVKLEDSGTYICQGFTNKELISECKITLNVVDNISDTLQCQVKFEKDKYSIEINQDVTMRALIECTSTHYSVSWFFNGEILEMKSDILSDIKNNGKIAELKIQNCNESHRGIYECMIENKDGNSSTARTELNVENIQIDCLNSVTKNIEITEGNELNLEVVSEIEKDLQFQWSKDDIDCSNNGIFNSTKNKNCFNLTKLKAEITDSGVYKFEGMVDGKLLELVHFTVQVNPIQSILTTDESRLKLICEDNEIILSDSKPLIISVEVLNWKQGVIQWLRNDMPFGDPCVLDNPFIDLYIESPQVNEHSGLYKCIVTNEKSETEFVEITVKFKDEKVVSPILGELLSCTVEEVNTIEDEKIELSVESRVPTKSIDSAVWLKDEKLLNETDPRLTIIMQPFCYNLILRDVKMTDAGMYSLKINESSVDILVKVRPKPIRKQTKEIFKNLKIPQIKKPLQDIFIRNEPETVKFEFEVEESGAKKAIWFFENEEIDAENMEFIQWSCDNYFALTIPAAGEKHCGKYTIQVANDMGCVRSDGRLSLMLRSEISEQMMESCCIAPLFTKKLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKPTIIFKDATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHLKGQPCLKWRAATVPEFCDSCVSGILPDYKVEYRNGRLSPWKIYQENIMQNETYLTQKIIDDAQEFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSPSVEKVKTIIKYDQLKQAEIESISKDGLSLKWSQWVPDQINKYIIQRKNSFSQDWEQIHSTIFGENCFVEMILSENFSRQLRILSLDDNKTELHDGYNILYIPSKDECIPTIPENLQVNDLTNYHEIFWSESKSIEIVDSPITYSLQSKVNNQFWFTITEKLDKCFYTNTRIDKYGVTGYRVLARNSIGSSPFSMEVFTKSLINILSNEQIIKSLRYFVINPREIEIKWHLCESIFDSGITTEDLSFQIEKKTVKEGSDWVPISNIVERNSILISITFEDENLFRIQPFYRDEKLSASRIFRMYVSKDLLVPDMSFTRPNLVIDSVTSCAIEWPEPELQSGFSPDGIEICVPSVLLVDLQYEIQFVVVDPIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTIDDTVIPGSNGEREITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTNIKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGEYCALDEVQDPIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIGFAEVKFNLRVDAHPEKKSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLYNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKPGNNLNAALDYIIDQIVKLMTYPEEMVPNFPSDMKNAIETLLIDSRPKVIFNSSLSNPEGSVSPPISQLSSRASSSSRDGINYERCDTPNDNSSEEVKSDRSETFPSADRLSVSNTTKELLFTVPLKDQTFKSDSTAGKITVTLTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNRYLLENLDRTQQYIARIIAQNKYGYSPYSIATSVFQNKIRNIHSLKQALIFNRKWMLTSRQSNHFNDLHDLIKDISSDDIRMNVIREHYSTLSQKSSGFAVLKLKNTNVNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFGEICDSSLGNRITFEEFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFKQDPQTIYEMEHQTISSTPLVDFVNANL 3988
BLAST of Serine/threonine kinase vs. Planmine SMEST
Match: SMESG000051697.1 (SMESG000051697.1) HSP 1 Score: 115.546 bits (288), Expect = 1.045e-24 Identity = 76/274 (27.74%), Postives = 135/274 (49.27%), Query Frame = 2 Query: 9587 KSVQINIGDVNDRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNM---GIGRSEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSH-WCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQLY-------------NEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIK 10357 + V+I G V+D Y +++L G++ + E ST F+ KF + + + + E + ++ H ++ + DA D+ + LI E L G L + IT+ + E++ I Q+ + ++H+ HLD+KPENI+ + +K+ F + + T+ F+APE+ + EP+ F +DMW++G+L+++ L G F GD Y N+D +S+ A FIRK L+ + +R+T + L H W IK Sbjct: 3544 QPVEIKNGSVHDHYEILEELGSGAFGQVYRCRELSTGKIFVAKFIDTPHQVDKNVVKHEIDTLNHLHHPKLLNLHDAFDDKDE-MCLIMEFLSGGELFDRITEDGYNMNEAEAANYIRQVCDGLKFMHDEGYIHLDLKPENIMCETSNSNRIKIIDFGLSTKLNPDEPVKVTTATAEFAAPEVAEIEPVGFYTDMWAVGVLSYVLLSGLSP--FGGDDDYETLQNVKKCAYDFNDDIFKNVSDDAKDFIRKLLIRQPQKRMTVYECLDHPWLIK 3814 HSP 2 Score: 74.7146 bits (182), Expect = 1.948e-12 Identity = 98/452 (21.68%), Postives = 169/452 (37.39%), Query Frame = 2 Query: 10787 LTCQLSLLGSEPISISWYKNQELLTDDSRIKLEVIKGGFLSCTILNATETDVGIFRCIARCHSLRTETSARLVLGDVPPQPEQLSVYYTNQEEVLLKWSPYLSAIDDVIYRIDIRTIDSRNKIRNWKTIGYSVDNRYLLENLDRTQQYIARIIAQNKYGYS-------PYSIATSVFQNKIRNIHSLKQALIFNRKWMLTSRQSNHFNDLHDLIKDISSD--DIRMNVIREHYSTLSQKSSG-----FAVLKLKNTN------VNFPEYIVQRTFKMEDICPAFDLCVRIKYYHFPILFG---------EICDSSLGNRITFEEFVPGGNLLSVLMARSV-YSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVK---EQESLTTHKPSIFKAPEYRYESITRYESDIWSLGILSFLLLATQLP 12043 + ++ +G W N E L + ++ +K TI NAT+++ GI+ + + D P +P + V V+L W+P +S Y + NW I S N L+NL + Y RIIA+N +G S P +I + + K N+ + NR N+ HDL +I+ + +HY L + SG + +L ++ P + + K E + + H P L E+C EF+ GG L + +E IRQ+ ++F+H +H +++P I+ T+ S IK+I F + K ++ T + F APE + +D+W++G+LS++LL+ P Sbjct: 3331 IVVKIPFVGFPRPKARWTLNGEELKPSRNVTID-LKERHAILTIENATKSNSGIYNLTLENELGSDSAKFEIEVNDAPNKPTGVRVDSHLDNGVILSWTPPISDSGKKGYISEYHIEKQEIPDGNWVRIATSRFNNVQLDNLRNGKDYNFRIIAENLHGRSEPSDKIGPITIGEGLIKPKKSNLDQSR-----NRGDYSGPDIDNYDKFYHDLWNRYKPQPVEIKNGSVHDHYEILEELGSGAFGQVYRCRELSTGKIFVAKFIDTPHQVDKNVVKHE--------IDTLNHLHHPKLLNLHDAFDDKDEMC--------LIMEFLSGGELFDRITEDGYNMNEAEAANYIRQVCDGLKFMHDEGYIHLDLKPENIMC--ETSNSNRIKII-----DFGLSTKLNPDEPVKVTTATAEFAAPEVAEIEPVGFYTDMWAVGVLSYVLLSGLSP 3753 HSP 3 Score: 58.9214 bits (141), Expect = 1.325e-7 Identity = 85/376 (22.61%), Postives = 141/376 (37.50%), Query Frame = 2 Query: 8444 PIVGSKIRGKDVKNLQWKPLQEDLEENTFNWENPDPTQEYLFRIVAKNQFGSGLPSQIVKLHPQIIIPDFSFIRLTIDDTVIPGSNGEREITLSWSPPRISPDLYIPFTVDVECRPVNYSYSDEEGWSVFKTN-IKKNRVDIADLDPNINYQLRIVPVTDFGIGKPSMVIKKIRRSDNLNSPTTEKAMMLQEKHCLAVPMFCCLSQKAELKFTKLMEYKLDKITWTFNNAKVDVNDERYKIFSAETYGIYFIIKNLEEDDFGEY-------CALDEVQD---PIQSFILIKSDAPTILNCLPNWSLTLHENFSISVQIDAQPPPEVVWRRNWKKIFSSYRTVITEDKEQGTYSLLISKCILSDGGEYSIRAENAIG 9538 P+ + K+ +WKPL ++ F D + Y FR+ A+N+FG G P + K II F V P E +TL W+ P+ I VE +P SDE W +K I +L + YQ R+ D G+ +PS ++ P ++ + V + S+ + K++ Y+++K N V G I NL+E++ E+ E D P + F P L+ + + + + ++D +P PEV W +N ++ S + +T+D G +L IS DGG + +N G Sbjct: 2555 PVSNYVVEMKEPSTGEWKPLSRFVKGTDFEVFGLDEGKPYSFRVKAENEFGIGEPLETDKQ----IIAQSPFSAPDCPTNVTPVDVDENSVTLEWTKPKNDGGKRI-AGYQVEYKPEG---SDE--WIKAPIGLVKTPSATIPNLKKDQKYQFRVKAKNDAGLSEPSQCTNTVQCKPKYTVPDAPSTPLIDKVGKDYVDL--SWSKPIKDGGNKVVGYQVEKRKKGGNWEPV---------TDKPIIGNQTTIPNLDENEEYEFRVRAVNAAGPGEPSDSTLPTKIFDKTAGTTPEFLSKITPTTSPIGGTATFQCRVDGKPTPEVKWLKNGIELRPSGKVKMTDD--DGLLTLEISDIDDKDGGNITCEIKNKAG 2907 HSP 4 Score: 58.151 bits (139), Expect = 2.208e-7 Identity = 80/332 (24.10%), Postives = 134/332 (40.36%), Query Frame = 2 Query: 6092 KLKDIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIIT-----------EAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLC--APVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGF-ETVSNIIEIPIRANSPILPPD---KPTIIFKDATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLV-DNEYSL-SLEPGVSYMFRVIAFNDFGISEPS-QSLISRIDRLKLVPDFSV 7027 K+ I+I + + + +P P+ WT VK + PN ++IT ++ + +G Y TN +G+D+ E ++V + KP P++ +E +K + LSW I + ++ L W+K+ + T++++ L + R A S G E + E I A +P PD KP II D V+I W K P + Y +E K+ + W V+ DL+ DN + S++ G Y +RV A N+ G S+PS S ++ K P F + Sbjct: 1444 KIAPIKIKVGQPATIELNYVGEPDPEAKWT--------------VKNIGVQPNENILITYKERSTRIDFTNSQRKHTGLYQLTVTNEVGHDSAEVELVV-------------LGKPSSPQGPLVISEVTKNS-AKLSWEKPKDDGGAEISNYVVEKMDLKKGKWEKVSDMINGTSFTVPK--LETGHEYKFRVSAESPLGTSEPLEG--EKSIEAKNPFDEPDAPSKPEIIDHDNNMVEIKWSPPKSDGGAPIQ-----HYIIERKEPKSNRWVKVNKDLIRDNTFKDDSVKTGKQYEYRVTAVNEAGPSKPSLPSDVATAKPSKEAPKFDL 1738 HSP 5 Score: 57.7658 bits (138), Expect = 2.483e-7 Identity = 108/449 (24.05%), Postives = 172/449 (38.31%), Query Frame = 2 Query: 6080 LFTKKLKDIEILSKENIRLNCRMMCD-PKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEV---------EDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYG----FETVSNIIEIPIRANSPILPPDKPTIIFK---DATCVKISWMRGKCKNLTPEESIGKIM--YSLEMKDNPKSSWQIVSNDLVDNEYSL--SLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSV-DPPWLHL-----KGQPCLKWRAATVPEFCDSCVSGILPDYKVEYR--NGRLSPWKIYQENIMQNETYLTQKIIDDAQEFRVSCRNKFGQNGPTRSYRLQANIVGKTSFRSP 7339 + K K I+ ++ E ++ P P++L +GE + + PNF + + EV +D G Y N G D+ + V D +P + D PL +T + K LSW + + + K ++ WK + + + T + + L + + R A +E+G ET II A SP PD PT + D V + W + P+ GK + Y +E K W LV + +L+ Y FRV A ND G+SEPSQ + ++ P ++V D P L K L W + + + + V Y+VE R G P + + I+ N+T + ++ EFRV N G P+ S L I KT+ +P Sbjct: 2431 ILDKNPKQIKAIAGEKFQIKIPYSGGYPPPEVLCELNGEPISAN------------PNFKVEVKPDEVVITNLNPQKQDQGHYNITLKNPKGSDSVPVKVTVFD-KPDKPDG------PLEVSQVTGDSCK-----LSWKPPKENGGSPVSNYVVEMKEPSTGEWKPLSRFVKGTDFEVFG--LDEGKPYSFRVKAENEFGIGEPLETDKQII-----AQSPFSAPDCPTNVTPVDVDENSVTLEWTK-------PKNDGGKRIAGYQVEYKPEGSDEWIKAPIGLVKTPSATIPNLKKDQKYQFRVKAKNDAGLSEPSQC----TNTVQCKPKYTVPDAPSTPLIDKVGKDYVDLSW-SKPIKDGGNKVVG-----YQVEKRKKGGNWEP--VTDKPIIGNQTTIPNLDENEEYEFRVRAVNAAGPGEPSDS-TLPTKIFDKTAGTTP 2828 HSP 6 Score: 56.225 bits (134), Expect = 7.687e-7 Identity = 86/345 (24.93%), Postives = 138/345 (40.00%), Query Frame = 2 Query: 6452 VILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKPTIIFKDA---TCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLVDNEYS--LSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLHLKGQPCLKWRAATVPEFCDSCVSGILPDYKVEYRNGRLSP---WKIYQENIMQNE-TYLT-----QKII--------DDAQEFRVSCRNKFGQN----------------GPTRSYRLQANIVGKTSFRSPSVEKVKTIIKY 7372 V L+W +D N I + +K L +W+K L + S + L + + R AI++ G S + + P PI P D PT D +K+SW + K + KI + K N W+ V + E + + ++PG FRVIA ND G SEPS+ +++ L + + P L+L G R TV D + KV Y G +P WK +E I ++ T+++ Q +I D+ + ++ +N GQ+ GP + +QAN V S++ P + I Y Sbjct: 1946 VTLAWKP-PISDGGNPIKGYQVEKKLVGGDWQKASPALAPGS-SQTVMNLIEGKQYEFRVRAINDAGPGEPSKVTK-PHTVKDPIFPADSPTTPNVDKITKNGIKLSWNKPK------HDGGSKIKEYIIEKKNKDGEWEPVKEVPANGENTAEIPMKPGEEAQFRVIAVNDAGPSEPSKP--TKV----LTAEDQPEAPKLNLSG-----LRDITVKAGQDFQI-------KVPYTGGFPTPIVNWKKNEEPITDDQRTHISVNPEDQVVILAVSNAKRSDSGKISLTLKNDSGQDIGSCEVKVLDVPAAPEGPLEASEIQANSV-TLSWKPPKDNGGEPITNY 2262 HSP 7 Score: 53.1434 bits (126), Expect = 6.951e-6 Identity = 99/409 (24.21%), Postives = 161/409 (39.36%), Query Frame = 2 Query: 6101 DIEILSKENIRLNCRMMCDPKPKILWTKDGETLDSKCLNRRVKILDEFPNFTLIITEAEVEDSGRYCCLGTNFLGYDTTEAVIIVTDSEPKESDSSRIIVKPLCAPVLTAEYSKGADVILSWTSVATTDTLNIIYNIEKQKSLTSTNWKKIMKNLTETTYSLSSSCLPPQESHLLRCVAISEYGFETVSNIIEIPIRANSPILPPDKP---TIIFKDATCVKISWMRGKCKNLTPEESIGKIMYSLEMKDNPKSSWQIVSNDLV--DNEYSLSLEPGVSYMFRVIAFNDFGISEPSQSLISRIDRLKLVPDFSVDPPWLH--LKGQPCLKWRAATVPEFCDSCVSGILPDYKVEYRN--GRLSPWKIYQENIMQNETYLTQKIIDDAQEFRVSCRNKFGQNGPTRSYRL 7300 +I + + E + L + PKP+ +WTK+G L K+ D+ + I + +DSG Y TN G D E +IV D +P + ++I + +E K L+W I I ++ ST W+KI + + S++ L + + R A+++ G + E+ I A +P P P I D V ++W P + Y +E K WQ S L ++ ++L G Y FRV A ND G EPS+ + + P S P + K L W P+ + +Y +E +N G P K N +N + K ++AQ FRV N G + P++ ++ Sbjct: 1748 EIRLKAGEKLNLPIAITGAPKPECVWTKNGIALPG-----NAKVTDKEDLTGIEIPSVKRDDSGVYKIKLTNPYGTDEAEIKVIVMD-KPGAPEEPKVI-------DILSESCK-----LTWNPPKDNGACEITDYIVEKCEEGSTYWQKIPGIIKDN--SMAVKNLEKDKRYKFRISAVNKMGTGKPAE-TEL-ITAKNPFDAPGSPEELKITQFDRMSVTLAWKPPISDGGNPIKG-----YQVEKKLV-GGDWQKASPALAPGSSQTVMNLIEGKQYEFRVRAINDAGPGEPSKVTKPHTVKDPIFPADSPTTPNVDKITKNGIKLSWNK---PKHDGGSK---IKEYIIEKKNKDGEWEPVKEVPAN-GENTAEIPMKPGEEAQ-FRVIAVNDAGPSEPSKPTKV 2120
BLAST of Serine/threonine kinase vs. Planmine SMEST
Match: SMESG000081259.1 (SMESG000081259.1) HSP 1 Score: 109.768 bits (273), Expect = 1.786e-23 Identity = 79/272 (29.04%), Postives = 131/272 (48.16%), Query Frame = 2 Query: 9620 DRYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGRSEFQCIQNI----------SHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLC--GFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGDQL-------------YNEDSNDAISNSACVFIRKCLLLKTGERLTSSDSLSHEWFIKP 10360 D Y +KL G ++ + I+K T EF KF + + +S I+ I +H+NI+++F + + + L+ E + G L ++I+ E + I Q++ V ++HE +V HLD+KPEN+++ +KL G + + K+D + M T+ F APE++ E I + +DMW+IG++T++ L G F GD + ED +S A FI LLL +R T++ L H W IKP Sbjct: 10 DIYKVGEKLGHGHFAEVKHCIDKQTNTEFAAKFIRVRQLLDSKSAGMSIEEIEREAHILKMLNHQNIIKLFFCHHL-GKTVALVLELVAGGELFDHISDSEKLSEEEASEFIEQILYGVQHMHEKKVVHLDLKPENVMIEDLDERKIKLIDFGLAREIKKQD--TIIEMQGTAEFLAPEVINYEAISYATDMWAIGVITYIMLTG--VSPFSGDDQSSTFQNIVTCKLDFEEDVCSDMSEMAKGFINSLLLLDPRKRSTANLCLKHHW-IKP 275 HSP 2 Score: 63.5438 bits (153), Expect = 2.850e-9 Identity = 50/200 (25.00%), Postives = 90/200 (45.00%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSI-FKAPEY-RYESITRYESDIWSLGILSFLLLATQLPAIEDACSDSDVHCCVKNTNTLLLPVPHTHFRAPKLSMLHRFSKSSRKFVHNSLKKSPNDRGNADYWLAHSWFK 12262 E V GG L + SE I Q+L +Q +H VVH +++P ++I + D + I L + +K+Q+++ + + F APE YE+I+ Y +D+W++G++++++L P S D +N T L + S+ ++ F+++ L P R A+ L H W K Sbjct: 94 ELVAGGELFDHISDSEKLSEEEASEFIEQILYGVQHMHEKKVVHLDLKPENVMI-----EDLDERKIKLIDFGLAREIKKQDTIIEMQGTAEFLAPEVINYEAIS-YATDMWAIGVITYIMLTGVSP-----FSGDDQSSTFQNIVTCKLDFEE--------DVCSDMSEMAKGFINSLLLLDPRKRSTANLCLKHHWIK 274
BLAST of Serine/threonine kinase vs. Planmine SMEST
Match: SMESG000011366.1 (SMESG000011366.1) HSP 1 Score: 104.375 bits (259), Expect = 4.191e-23 Identity = 80/303 (26.40%), Postives = 142/303 (46.86%), Query Frame = 2 Query: 9623 RYYTMKKLAKGSYSRCQIVIEKSTQIEFIGKFFEINNMGIGR---------SEFQCIQNISHRNIVEIFDAIAMPDQYLVLIYEKLQGLSLAEYITQLSHWCESQVRIIIHQLIQAVSYLHEHRVCHLDIKPENIIMTGKYNEILKLCGFSNAVPKEDFGSRRHMGLTSPFSAPELLKGEPIQFNSDMWSIGILTFLCLHGHLKVNFEGD-QLYNE------DSNDA----ISNSACVFIRKCLLLKTGERLTSSDSLSH--EWFIKPGNNLNAALDYII--DQIVKLMTYPEEMVPNFPSDM 10459 +Y + + KG Y+ ++ T I++ KF + + + R E + + +SH NI++I++A D VLI E + G L EYI+ E + + Q++ V ++H + HLD+KPENI++ + +K+ F + D G T F APE++ +P+ F +DMWSIGI+ ++ L G+ E +++N D ND+ +S+ A F+ ++ +RL+ D L H + P + + I D++ KL Y + P+ P+ M Sbjct: 11 KYILGQHIGKGHYATVKMCTNIETNIDYAAKFIKKKRIAMSRIGTKTDDIVREARILSKLSHPNIIQIYEAFDRKDMS-VLILELVTGGELFEYISNKVTLSEEEASKFMRQILLGVHHMHSKNILHLDLKPENILVEDPDTQKIKIIDFGFSKEINDAPILELQG-TPEFVAPEVINYDPLTFATDMWSIGIIAYIMLTGNSPFYHETQSEVFNRITRCQLDLNDSTCSMMSDLAKSFLSSLIVKTPSKRLSCEDCLKHFGSKLVYPEKKIERKRNSFISQDKLNKLRNY--VVSPSRPTSM 309 HSP 2 Score: 58.151 bits (139), Expect = 7.742e-8 Identity = 35/126 (27.78%), Postives = 60/126 (47.62%), Query Frame = 2 Query: 11669 EFVPGGNLLSVLMARSVYSEFTVVTIIRQLLGTIQFLHSNNVVHGNIEPTKILISRRTNQSFDIKLIGLENCQFVGTVKEQESLTTHKPSIFKAPEY-RYESITRYESDIWSLGILSFLLLATQLP 12043 E V GG L + + SE +RQ+L + +HS N++H +++P IL+ Q I G F + + L F APE Y+ +T + +D+WS+GI+++++L P Sbjct: 93 ELVTGGELFEYISNKVTLSEEEASKFMRQILLGVHHMHSKNILHLDLKPENILVEDPDTQKIKIIDFG-----FSKEINDAPILELQGTPEFVAPEVINYDPLT-FATDMWSIGIIAYIMLTGNSP 212 The following BLAST results are available for this feature:
BLAST of Serine/threonine kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Serine/threonine kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Serine/threonine kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Serine/threonine kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Serine/threonine kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Serine/threonine kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Serine/threonine kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Serine/threonine kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Serine/threonine kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Serine/threonine kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Serine/threonine kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Serine/threonine kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Serine/threonine kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Serine/threonine kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30005039 ID=SMED30005039|Name=Serine/threonine kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=12483bpback to top protein sequence of SMED30005039-orf-1 >SMED30005039-orf-1 ID=SMED30005039-orf-1|Name=SMED30005039-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=4095bp MIFQLLWSLIGIFSILGYLFLWLQQRLERDNAILSKPRSSNLSDEEYLNNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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