AP complex subunit sigma

Overview


Name	AP complex subunit sigma
Smed ID	SMED30005038
Length (bp)	996

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of AP complex subunit sigma (SMED30005038) t-SNE clustered cells

Violin plots show distribution of expression levels for AP complex subunit sigma (SMED30005038) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of AP complex subunit sigma (SMED30005038) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for AP complex subunit sigma (SMED30005038) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30005038

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
anterior region of the whole animal	SMED30005038	SMESG000019676.1	dd_Smed_v4_9393_0_1	dd_Smed_v4	PMID:27063937 Scimone et al., 2016
gut	SMED30005038	SMESG000019676.1	dd_Smed_v4_9393_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30005038	SMESG000019676.1	dd_Smed_v4_9393_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30005038	SMESG000019676.1	dd_Smed_v4_9393_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Category 2 cell	SMED30005038	SMESG000019676.1	dd_Smed_v4_9393_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Human
Match: AP1S2 (adaptor related protein complex 1 subunit sigma 2 [Source:HGNC Symbol;Acc:HGNC:560])

HSP 1 Score: 239.58 bits (610), Expect = 5.358e-79
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Human
Match: AP1S2 (adaptor related protein complex 1 subunit sigma 2 [Source:HGNC Symbol;Acc:HGNC:560])

HSP 1 Score: 239.195 bits (609), Expect = 5.959e-79
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Human
Match: AP1S2 (adaptor related protein complex 1 subunit sigma 2 [Source:HGNC Symbol;Acc:HGNC:560])

HSP 1 Score: 239.195 bits (609), Expect = 8.283e-79
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Human
Match: AP1S2 (adaptor related protein complex 1 subunit sigma 2 [Source:HGNC Symbol;Acc:HGNC:560])

HSP 1 Score: 238.424 bits (607), Expect = 8.748e-79
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Human
Match: AP1S2 (adaptor related protein complex 1 subunit sigma 2 [Source:HGNC Symbol;Acc:HGNC:560])

HSP 1 Score: 238.424 bits (607), Expect = 8.748e-79
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Celegans
Match: aps-1 (AP complex subunit sigma [Source:UniProtKB/TrEMBL;Acc:O16369])

HSP 1 Score: 253.447 bits (646), Expect = 6.692e-85
Identity = 117/142 (82.39%), Postives = 136/142 (95.77%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MMQ+MLLFSRQGKLRLQKWYT+YPDK KKKI R+LI QILARKPKMC+FLE+KD+K+V+KRYASLYFCCA+++ +NELI+LEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+ G++QET+KK VLKAI+AQD+IQ
Sbjct:    1 MMQYMLLFSRQGKLRLQKWYTAYPDKQKKKICRELITQILARKPKMCAFLEYKDLKVVYKRYASLYFCCAIEQNDNELITLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLAGEIQETSKKQVLKAIAAQDLIQ 142

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Celegans
Match: aps-2 (AP complex subunit sigma [Source:UniProtKB/TrEMBL;Acc:Q19123])

HSP 1 Score: 137.502 bits (345), Expect = 6.156e-40
Identity = 61/135 (45.19%), Postives = 96/135 (71.11%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAI 421
            M++F+L+ +R GK RL KWY  + D  K+K+  ++ A +  R  K  +F+E+++ KIV++RYA LYFC  VD T+N L  LE IH +VE+L++YF +VCELD++FNF K Y ++DE  + G+++ET++  VLK +
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHACVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCICVDITDNNLYYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQL 135

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Celegans
Match: aps-3 (AdaPtin, Small chain (Clathrin associated complex) [Source:UniProtKB/TrEMBL;Acc:Q8T874])

HSP 1 Score: 114.775 bits (286), Expect = 1.438e-30
Identity = 57/148 (38.51%), Postives = 94/148 (63.51%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEW------KDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            M++ +L+ +  GK RL K+Y  YP++ +++I R+    +  R   +C+FLE        D +++++ YA+LYF   VD +E+EL  L++I  +VE LD+ F +VCELD+IF+ ++ + IL E ++GG V ETN   +L+ I  QD IQ
Sbjct:    1 MIKAILVINNHGKPRLLKFYQHYPEEKQQQIVRETFQLVSKRDDNVCNFLEGGTLIDGNDYRLIYRHYATLYFIFCVDSSESELGILDLIQVFVETLDRCFENVCELDLIFHVDRVHHILGEIVMGGMVLETNMNEILQRIQEQDKIQ 148

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Fly
Match: AP-1sigma (gene:FBgn0039132 transcript:FBtr0305039)

HSP 1 Score: 249.98 bits (637), Expect = 1.576e-83
Identity = 115/142 (80.99%), Postives = 133/142 (93.66%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MM FMLLFSRQGKLRLQKWY +YPDKVKKKI R+L+  ILARKPKMCSFLEWKD KIV+KRYASLYFCCA+++ +NEL++LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDE LIGG++QET+KK VLKAI++QD++Q
Sbjct:    1 MMLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLEWKDCKIVYKRYASLYFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQETSKKNVLKAIASQDLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Fly
Match: AP-1sigma (gene:FBgn0039132 transcript:FBtr0305040)

HSP 1 Score: 249.98 bits (637), Expect = 1.576e-83
Identity = 115/142 (80.99%), Postives = 133/142 (93.66%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MM FMLLFSRQGKLRLQKWY +YPDKVKKKI R+L+  ILARKPKMCSFLEWKD KIV+KRYASLYFCCA+++ +NEL++LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDE LIGG++QET+KK VLKAI++QD++Q
Sbjct:    1 MMLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLEWKDCKIVYKRYASLYFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQETSKKNVLKAIASQDLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Fly
Match: AP-1sigma (gene:FBgn0039132 transcript:FBtr0335244)

HSP 1 Score: 249.98 bits (637), Expect = 1.807e-83
Identity = 115/142 (80.99%), Postives = 133/142 (93.66%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MM FMLLFSRQGKLRLQKWY +YPDKVKKKI R+L+  ILARKPKMCSFLEWKD KIV+KRYASLYFCCA+++ +NEL++LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDE LIGG++QET+KK VLKAI++QD++Q
Sbjct:    1 MMLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLEWKDCKIVYKRYASLYFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQETSKKNVLKAIASQDLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Fly
Match: AP-1sigma (gene:FBgn0039132 transcript:FBtr0084496)

HSP 1 Score: 249.21 bits (635), Expect = 3.201e-83
Identity = 115/142 (80.99%), Postives = 133/142 (93.66%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MM FMLLFSRQGKLRLQKWY +YPDKVKKKI R+L+  ILARKPKMCSFLEWKD KIV+KRYASLYFCCA+++ +NEL++LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDE LIGG++QET+KK VLKAI++QD++Q
Sbjct:    1 MMLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLEWKDCKIVYKRYASLYFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQETSKKNVLKAIASQDLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Fly
Match: AP-2sigma (gene:FBgn0043012 transcript:FBtr0084103)

HSP 1 Score: 137.117 bits (344), Expect = 1.211e-39
Identity = 60/135 (44.44%), Postives = 96/135 (71.11%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAI 421
            M++F+L+ +R GK RL KWY ++ D  K+K+  ++ A +  R  K  +F+E+++ KIV++RYA LYFC  VD  +N L  LE IH +VE+L++YF +VCELD++FNF K Y ++DE  + G+++ET++  VLK +
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMNFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCICVDVNDNNLCYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRETSQTKVLKQL 135

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Zebrafish
Match: ap1s2 (adaptor related protein complex 1 subunit sigma 2 [Source:ZFIN;Acc:ZDB-GENE-030131-5448])

HSP 1 Score: 236.884 bits (603), Expect = 3.982e-78
Identity = 110/141 (78.01%), Postives = 126/141 (89.36%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    D  KKKI+R++I  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCAV+  ENELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAY+ILDEF++GG+ QET+KK VLKAI   DM+Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDTQKKKISREVIQMVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEDQENELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYYILDEFILGGEAQETSKKNVLKAIEQADMLQ 141

[Close]

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    D  KKKI+R++I  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCAV+  ENELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAY+ILDEF++GG+ QET+KK VLKAI   DM+Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDTQKKKISREVIQMVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEDQENELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYYILDEFILGGEAQETSKKNVLKAIEQADMLQ 141

[Close]

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    D  KKKI+R++I  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCAV+  ENELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAY+ILDEF++GG+ QET+KK VLKAI   DM+Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDTQKKKISREVIQMVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEDQENELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYYILDEFILGGEAQETSKKNVLKAIEQADMLQ 141

[Close]

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    D  KKKI+R++I  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCAV+  ENELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAY+ILDEF++GG+ QET+KK VLKAI   DM+Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDTQKKKISREVIQMVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEDQENELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYYILDEFILGGEAQETSKKNVLKAIEQADMLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Zebrafish
Match: ap1s1 (adaptor related protein complex 1 subunit sigma 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1119])

HSP 1 Score: 234.958 bits (598), Expect = 1.850e-77
Identity = 108/142 (76.06%), Postives = 130/142 (91.55%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MM+FMLLFSRQGKLRLQKWYT+  ++ KKK+ R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCAV+  +NELI+LEVIHR+VELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG++Q+T+KK VLKAI   D++Q
Sbjct:    1 MMRFMLLFSRQGKLRLQKWYTATAERDKKKMVRELMQVVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEEQDNELITLEVIHRFVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQADLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Match: tbkbp1 (TBK1 binding protein 1 [Source:Xenbase;Acc:XB-GENE-962068])

HSP 1 Score: 237.654 bits (605), Expect = 2.464e-78
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    7 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 147

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Match: tbkbp1 (TBK1 binding protein 1 [Source:Xenbase;Acc:XB-GENE-962068])

HSP 1 Score: 234.572 bits (597), Expect = 3.763e-77
Identity = 111/142 (78.17%), Postives = 127/142 (89.44%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKR-YASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KR YASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRLYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Match: tbkbp1 (TBK1 binding protein 1 [Source:Xenbase;Acc:XB-GENE-962068])

HSP 1 Score: 234.187 bits (596), Expect = 4.386e-77
Identity = 111/142 (78.17%), Postives = 127/142 (89.44%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKR-YASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KR YASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRLYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Match: plekha3 (pleckstrin homology domain containing A3 [Source:Xenbase;Acc:XB-GENE-961095])

HSP 1 Score: 231.491 bits (589), Expect = 6.896e-76
Identity = 106/141 (75.18%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            M+FMLLFSRQGKLRLQKWY +  ++ KKK+ RDL+  +L+RKPKMCSFLEWKD K+V+KRYASLYFCCAV+  +NEL++LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG++Q+T+KK VLKAI   DM+Q
Sbjct:    1 MRFMLLFSRQGKLRLQKWYVAISERDKKKLVRDLMQTVLSRKPKMCSFLEWKDFKVVYKRYASLYFCCAVEDQDNELLTLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQSDMLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Match: plekha3 (pleckstrin homology domain containing A3 [Source:Xenbase;Acc:XB-GENE-961095])

HSP 1 Score: 230.72 bits (587), Expect = 1.024e-75
Identity = 106/141 (75.18%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            M+FMLLFSRQGKLRLQKWY +  ++ KKK+ RDL+  +L+RKPKMCSFLEWKD K+V+KRYASLYFCCAV+  +NEL++LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG++Q+T+KK VLKAI   DM+Q
Sbjct:    1 MRFMLLFSRQGKLRLQKWYVAISERDKKKLVRDLMQTVLSRKPKMCSFLEWKDFKVVYKRYASLYFCCAVEDQDNELLTLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQSDMLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Mouse
Match: Ap1s2 (adaptor-related protein complex 1, sigma 2 subunit [Source:MGI Symbol;Acc:MGI:1889383])

HSP 1 Score: 239.58 bits (610), Expect = 3.679e-79
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Mouse
Match: Ap1s2 (adaptor-related protein complex 1, sigma 2 subunit [Source:MGI Symbol;Acc:MGI:1889383])

HSP 1 Score: 239.195 bits (609), Expect = 4.091e-79
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Mouse
Match: Ap1s2 (adaptor-related protein complex 1, sigma 2 subunit [Source:MGI Symbol;Acc:MGI:1889383])

HSP 1 Score: 238.81 bits (608), Expect = 6.204e-79
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Mouse
Match: Ap1s1 (adaptor protein complex AP-1, sigma 1 [Source:MGI Symbol;Acc:MGI:1098244])

HSP 1 Score: 231.876 bits (590), Expect = 2.323e-76
Identity = 107/142 (75.35%), Postives = 128/142 (90.14%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MM+FMLLFSRQGKLRLQKWY +  DK +KK+ R+L+  +LARKPKMCSFLEW+D+K+V+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG VQ+T+KK VLKAI   D++Q
Sbjct:    1 MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Mouse
Match: Ap1s1 (adaptor protein complex AP-1, sigma 1 [Source:MGI Symbol;Acc:MGI:1098244])

HSP 1 Score: 232.261 bits (591), Expect = 2.873e-76
Identity = 107/142 (75.35%), Postives = 128/142 (90.14%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MM+FMLLFSRQGKLRLQKWY +  DK +KK+ R+L+  +LARKPKMCSFLEW+D+K+V+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG VQ+T+KK VLKAI   D++Q
Sbjct:    1 MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Match: sp|Q9DB50|AP1S2_MOUSE (AP-1 complex subunit sigma-2 OS=Mus musculus OX=10090 GN=Ap1s2 PE=1 SV=1)

HSP 1 Score: 239.58 bits (610), Expect = 2.573e-78
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Match: sp|Q3ZBS3|AP1S2_BOVIN (AP-1 complex subunit sigma-2 OS=Bos taurus OX=9913 GN=AP1S2 PE=2 SV=1)

HSP 1 Score: 239.58 bits (610), Expect = 2.573e-78
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Match: sp|P56377|AP1S2_HUMAN (AP-1 complex subunit sigma-2 OS=Homo sapiens OX=9606 GN=AP1S2 PE=1 SV=1)

HSP 1 Score: 239.195 bits (609), Expect = 2.862e-78
Identity = 111/141 (78.72%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+VQET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Match: sp|P61967|AP1S1_MOUSE (AP-1 complex subunit sigma-1A OS=Mus musculus OX=10090 GN=Ap1s1 PE=1 SV=1)

HSP 1 Score: 232.261 bits (591), Expect = 2.009e-75
Identity = 107/142 (75.35%), Postives = 128/142 (90.14%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MM+FMLLFSRQGKLRLQKWY +  DK +KK+ R+L+  +LARKPKMCSFLEW+D+K+V+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG VQ+T+KK VLKAI   D++Q
Sbjct:    1 MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Match: sp|P61966|AP1S1_HUMAN (AP-1 complex subunit sigma-1A OS=Homo sapiens OX=9606 GN=AP1S1 PE=1 SV=1)

HSP 1 Score: 232.261 bits (591), Expect = 2.009e-75
Identity = 107/142 (75.35%), Postives = 128/142 (90.14%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MM+FMLLFSRQGKLRLQKWY +  DK +KK+ R+L+  +LARKPKMCSFLEW+D+K+V+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG VQ+T+KK VLKAI   D++Q
Sbjct:    1 MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. TrEMBL
Match: A0A2C9M9V4 (AP complex subunit sigma OS=Biomphalaria glabrata OX=6526 GN=106065610 PE=3 SV=1)

HSP 1 Score: 255.373 bits (651), Expect = 4.458e-82
Identity = 117/142 (82.39%), Postives = 136/142 (95.77%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MMQFMLLFSRQGKLRLQKW+T+YPD+ KKKI R+LIA +LARKPKMCSFLEWKD+KIV+KRYASLYFCCA++  +NEL++LEVIHRYVELLDKYFGSVCELDIIFNFEKAYF+LDEFL+GG+VQET+KK VLKAI+AQD++Q
Sbjct:    1 MMQFMLLFSRQGKLRLQKWFTAYPDRTKKKITRELIALVLARKPKMCSFLEWKDLKIVYKRYASLYFCCAIENDDNELLTLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFMLDEFLLGGEVQETSKKNVLKAIAAQDLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. TrEMBL
Match: A0A2C9M9V9 (AP complex subunit sigma OS=Biomphalaria glabrata OX=6526 GN=106065610 PE=3 SV=1)

HSP 1 Score: 254.988 bits (650), Expect = 4.692e-82
Identity = 117/142 (82.39%), Postives = 136/142 (95.77%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MMQFMLLFSRQGKLRLQKW+T+YPD+ KKKI R+LIA +LARKPKMCSFLEWKD+KIV+KRYASLYFCCA++  +NEL++LEVIHRYVELLDKYFGSVCELDIIFNFEKAYF+LDEFL+GG+VQET+KK VLKAI+AQD++Q
Sbjct:    1 MMQFMLLFSRQGKLRLQKWFTAYPDRTKKKITRELIALVLARKPKMCSFLEWKDLKIVYKRYASLYFCCAIENDDNELLTLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFMLDEFLLGGEVQETSKKNVLKAIAAQDLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. TrEMBL
Match: A0A2C9M9V0 (AP complex subunit sigma OS=Biomphalaria glabrata OX=6526 GN=106065610 PE=3 SV=1)

HSP 1 Score: 254.988 bits (650), Expect = 5.912e-82
Identity = 117/142 (82.39%), Postives = 136/142 (95.77%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MMQFMLLFSRQGKLRLQKW+T+YPD+ KKKI R+LIA +LARKPKMCSFLEWKD+KIV+KRYASLYFCCA++  +NEL++LEVIHRYVELLDKYFGSVCELDIIFNFEKAYF+LDEFL+GG+VQET+KK VLKAI+AQD++Q
Sbjct:    1 MMQFMLLFSRQGKLRLQKWFTAYPDRTKKKITRELIALVLARKPKMCSFLEWKDLKIVYKRYASLYFCCAIENDDNELLTLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFMLDEFLLGGEVQETSKKNVLKAIAAQDLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. TrEMBL
Match: A0A3P7M6W9 (AP complex subunit sigma OS=Cylicostephanus goldi OX=71465 GN=CGOC_LOCUS9130 PE=3 SV=1)

HSP 1 Score: 254.218 bits (648), Expect = 7.048e-82
Identity = 119/142 (83.80%), Postives = 136/142 (95.77%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MMQFMLLFSRQGKLRLQKWYT+Y DK+KKKI R+LI QILARKPKMC+FLE+KD+KIV+KRYASLYFCCA+++T+NELI LEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+ G++QET+KK VLKAI+AQD+IQ
Sbjct:    1 MMQFMLLFSRQGKLRLQKWYTAYQDKMKKKICRELITQILARKPKMCAFLEYKDLKIVYKRYASLYFCCAIEQTDNELICLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLAGEIQETSKKQVLKAIAAQDLIQ 142

[Close]

BLAST of AP complex subunit sigma vs. TrEMBL
Match: G0MXN1 (AP complex subunit sigma OS=Caenorhabditis brenneri OX=135651 GN=Cbn-aps-1 PE=3 SV=1)

HSP 1 Score: 254.603 bits (649), Expect = 7.124e-82
Identity = 118/142 (83.10%), Postives = 136/142 (95.77%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MMQ+MLLFSRQGKLRLQKWYT+YPDK KKKI R+LI QILARKPKMC+FLE+KDMK+V+KRYASLYFCCA+++ +NELI+LEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+ G++QET+KK VLKAI+AQD+IQ
Sbjct:    1 MMQYMLLFSRQGKLRLQKWYTAYPDKQKKKICRELITQILARKPKMCAFLEYKDMKVVYKRYASLYFCCAIEQNDNELITLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLAGEIQETSKKQVLKAIAAQDLIQ 142

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Match: AP1S2 (AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc:103030203])

HSP 1 Score: 238.039 bits (606), Expect = 1.164e-78
Identity = 110/141 (78.01%), Postives = 126/141 (89.36%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+ QET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEAQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Match: AP1S2 (AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc:103030203])

HSP 1 Score: 236.498 bits (602), Expect = 3.810e-78
Identity = 110/141 (78.01%), Postives = 126/141 (89.36%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+ QET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEAQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Match: ap1s1 (AP-1 complex subunit sigma-1A [Source:NCBI gene;Acc:103041452])

HSP 1 Score: 232.646 bits (592), Expect = 1.173e-76
Identity = 107/141 (75.89%), Postives = 129/141 (91.49%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            M+FMLLFSRQGKLRLQKWYT+  ++ KKK+ R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCAV+  +NELI+LEVIHR+VELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG++Q+T+KK VLKAI   D++Q
Sbjct:    1 MRFMLLFSRQGKLRLQKWYTATAERDKKKMVRELMQVVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEEQDNELITLEVIHRFVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQADLLQ 141

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BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Match: ENSAMXT00000055261.1 (AP-1 complex subunit sigma-2-like [Source:NCBI gene;Acc:103023733])

HSP 1 Score: 220.705 bits (561), Expect = 6.071e-72
Identity = 98/142 (69.01%), Postives = 124/142 (87.32%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MM+F+LLFSRQGKLRLQKW+    ++ KKKI RD+   +LARKP+ C+FL W+D+KIV+KRYASLYFCC ++  +NEL++LEV+HRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG++QET+K+ + K+I A DM+Q
Sbjct:    1 MMRFLLLFSRQGKLRLQKWFLPMTEREKKKIIRDMTTMVLARKPRTCNFLHWRDLKIVYKRYASLYFCCGLEDQDNELLALEVLHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQETSKQSIAKSIEASDMLQ 142

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Match: ENSAMXT00000046966.1 (pep primary_assembly:Astyanax_mexicanus-2.0:5:15033972:15038356:1 gene:ENSAMXG00000031582.1 transcript:ENSAMXT00000046966.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 219.164 bits (557), Expect = 2.169e-71
Identity = 100/132 (75.76%), Postives = 119/132 (90.15%), Query Frame = 2

Query:   47 QGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            +GKLRLQKWY +  D  KKKI+R++I  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCAV+  ENELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAY+ILDEF++GG+ QET+KK+VLKAI   DM+Q
Sbjct:   10 RGKLRLQKWYVALSDTQKKKISREVIQMVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEDQENELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYYILDEFILGGEAQETSKKIVLKAIEQADMLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Sea Lamprey
Match: ap2s1 (adaptor related protein complex 2 subunit sigma 1 [Source:ZFIN;Acc:ZDB-GENE-040426-2174])

HSP 1 Score: 136.732 bits (343), Expect = 3.571e-40
Identity = 60/135 (44.44%), Postives = 95/135 (70.37%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAI 421
            M++F+L+ +R GK RL KWY  + D  K+K+  ++ A +  R  K  +F+E+++ KIV++RYA LYFC  VD  +N L  LE IH +VE+L++YF +VCELD++FNF K Y ++DE  + G+++ET++  VLK +
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQL 135

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Sea Lamprey
Match: ap3s2 (adaptor related protein complex 3 subunit sigma 2 [Source:ZFIN;Acc:ZDB-GENE-040718-274])

HSP 1 Score: 111.309 bits (277), Expect = 8.002e-30
Identity = 58/148 (39.19%), Postives = 95/148 (64.19%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEW------KDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            M++ +L+F+  GK RL K+Y  Y D ++++I R+    +  R   +C+FLE        D K++++ YA+LYF   VD  E+EL  L++I  +VE LDK F +VCELD+IF+ +K ++IL+E ++GG V ETN   ++  I AQ+ ++
Sbjct:    1 MIKAILVFNNHGKPRLSKFYKFYED-MQQQIIRETFHLVSKRDDNVCNFLEGGTLIGGSDYKLIYRHYATLYFVFCVDSCESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHYILNEMVMGGMVLETNMNEIVNQIEAQNKLE 147

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Yeast
Match: APS1 (Small subunit of the clathrin-associated adaptor complex AP-1; AP-1 is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex [Source:SGD;Acc:S000004160])

HSP 1 Score: 160.999 bits (406), Expect = 1.808e-49
Identity = 74/143 (51.75%), Postives = 106/143 (74.13%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDR-TENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLI-GGQVQETNKKMVLKAISAQDMIQ 442
            ++++LL SRQGK+RL+KWYT+     K KI +DL   ILARKPKMC+ +E+ D K+V+KRYASLYF   +    +NEL++LE+IHR+VE +D YFG+VCELDIIFNF K Y IL+E ++  G + E+++K VL  ++  D ++
Sbjct:    4 LKYLLLVSRQGKIRLKKWYTAMSAGEKAKIVKDLTPTILARKPKMCNIIEYNDHKVVYKRYASLYFIVGMTPDVDNELLTLEIIHRFVETMDTYFGNVCELDIIFNFSKVYDILNEMIMCDGSIAESSRKEVLHHVTVMDTME 146

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Yeast
Match: APS2 (Small subunit of the clathrin-associated adaptor complex AP-2; AP-2 is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex [Source:SGD;Acc:S000003819])

HSP 1 Score: 119.013 bits (297), Expect = 1.811e-33
Identity = 64/144 (44.44%), Postives = 97/144 (67.36%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQIL----ARKPKMCS-FLEWKD-MKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQD 433
            +QF+L F++QG +RL +W+  +    ++  ++D IAQI     +R  K  S F+E+ D  K++++RYA LYF   VD  ++E I L  IH +VE+LD +FG+VCELDI+FNF K Y I+DE  IGG++QE +K M+L+ +S  D
Sbjct:    3 VQFILCFNKQGVVRLVRWFDVHSSDPQR--SQDAIAQIYRLISSRDHKHQSNFVEFSDSTKLIYRRYAGLYFVMGVDLLDDEPIYLCHIHLFVEVLDAFFGNVCELDIVFNFYKVYMIMDEMFIGGEIQEISKDMLLERLSILD 144

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Yeast
Match: APS3 (Small subunit of the clathrin-associated adaptor complex AP-3; involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003561])

HSP 1 Score: 73.9442 bits (180), Expect = 3.255e-16
Identity = 48/154 (31.17%), Postives = 86/154 (55.84%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPK--MCSFLEWKD-----------------MKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAI 421
            M+  +L+F+++ + RL K+YT   D  K+K+  + + ++++++      SFL                     ++I++K YA+LYF   VD  E+EL  L++I  +VE LD+ F  V ELD+IFN++    +L+E + GG V ETN   ++ ++
Sbjct:    1 MIHAVLIFNKKCQPRLVKFYTPV-DLPKQKLLLEQVYELISQRNSDFQSSFLVTPPSLLLSNENNNDEVNNEDIQIIYKNYATLYFTFIVDDQESELAILDLIQTFVESLDRCFTEVNELDLIFNWQTLESVLEEIVQGGMVIETNVNRIVASV 153

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Yeast
Match: YLR171W_mRNA (Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000004161])

HSP 1 Score: 55.4546 bits (132), Expect = 3.269e-10
Identity = 45/106 (42.45%), Postives = 55/106 (51.89%), Query Frame = -1

Query:   16 ISNSHTLPKYLSNNSTYLCITSKDINSFSVLSTAQQ-K*RLAYLLNTIFISFHSKNEHIFGFLARICAIKSLAIFFLTLSGYDVYHFCSRSLPC--RLNNSINCII 324
            +S+S TLPKY+S  ST   I SK  +S S        K RLAY L T   S +S   HI GFLA I  +KS  IF  + +   VYHF +   PC    N   NC+I
Sbjct:    1 MSSSQTLPKYVSIVSTNRWIISKVSSSLSTSGVIPTIKYRLAYRLYTTLWSLYSMMLHILGFLANIVGVKSFTIFAFSPADIAVYHFFNLIFPCLETSNKYFNCVI 106

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Nematostella
Match: EDO45252 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTE2])

HSP 1 Score: 231.876 bits (590), Expect = 8.743e-77
Identity = 107/139 (76.98%), Postives = 125/139 (89.93%), Query Frame = 2

Query:   26 FMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            FMLLFSRQGK+RLQKWYT+   K KKKI RDL+  +L+RKPKMCSFLE+KDMK+ +KRYASLYFC  ++  +NEL++LEVIHRYVELLDKYFGSVCELDIIFNFEKAYF+LDE LIGG+VQET+KK VLKAISAQD++Q
Sbjct:    2 FMLLFSRQGKIRLQKWYTAISQKEKKKITRDLVTTVLSRKPKMCSFLEYKDMKVCYKRYASLYFCVGIENDDNELLTLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFMLDELLIGGEVQETSKKNVLKAISAQDLLQ 140

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Nematostella
Match: EDO38137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDU6])

HSP 1 Score: 137.117 bits (344), Expect = 5.525e-40
Identity = 64/141 (45.39%), Postives = 97/141 (68.79%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWY--TSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQD 433
            M++F+L+ ++QG  RL ++Y  T   D+V   +  ++I + LAR    CSF+E+++ K V++RYASLYF   +D TENEL  +E IH +VE+LD+YF SVCELDI+FN +K + +LDE ++ G + ETNK  VL  ++  D
Sbjct:    1 MLKFILIVNKQGHTRLSQYYEYTKIEDRVS--LEAEIIRKCLARSENQCSFIEYQNFKAVYRRYASLYFIIGIDSTENELGIMEFIHNFVEILDRYFDSVCELDIMFNIDKVHMLLDEMVMNGHIVETNKNRVLAPVTELD 139

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Nematostella
Match: EDO42183 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S269])

HSP 1 Score: 133.265 bits (334), Expect = 1.703e-38
Identity = 58/135 (42.96%), Postives = 97/135 (71.85%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAIS 424
            ++F+L+ +R GK RL KWY ++ D  K+K+  ++ A +  R  K  +F+E+++ KIV++RYA LYFC  VD ++N L  LE IH +VE+L+++F +VCELD++FNF K Y ++DE  + G+++ET++  VLK ++
Sbjct:    2 IRFILIQNRAGKTRLAKWYMNFDDDEKQKLIEEVHALVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCFCVDVSDNNLYYLEAIHNFVEVLNEFFHNVCELDLVFNFYKVYSVVDEMFLAGELRETSQSKVLKQLN 136

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Nematostella
Match: EDO42407 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1Q2])

HSP 1 Score: 115.161 bits (287), Expect = 5.894e-31
Identity = 66/185 (35.68%), Postives = 107/185 (57.84%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWK------DMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQXXXXXXXXXXXXXGLMSKSSQ*ITIVCNYLTVLSRLS 553
            M++ +L+F+  GK RL K+Y  Y + ++++I ++    +  R   +C+FLE        D K+V++ YA+LYF   VD +E+EL  L++I  +VE LDK F +VCELD+IF+ +K + IL E ++GG V ETN   +L  I AQ+ ++           E G+ +   + ++ V NY   L  LS
Sbjct:    1 MIKGILIFNNHGKPRLTKFYQHYSEDMQQQIIKETFHLVSRRDDNVCNFLEGGSLIGGADFKLVYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHHILAEIVMGGMVLETNMSEILTHIEAQNKLE---------KSEAGISAAPQKAMSAVRNYSPNLQNLS 176

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Medaka
Match: AP1S2 (AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc:101157435])

HSP 1 Score: 239.965 bits (611), Expect = 1.852e-79
Identity = 112/141 (79.43%), Postives = 127/141 (90.07%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK +KKI+RDL+  ILARKPKMCSFLEW+D+KIV+KRYASLYFCCAV+  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+ QET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKERKKISRDLVQTILARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEAQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Medaka
Match: zgc:162858 (AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc:101174095])

HSP 1 Score: 237.654 bits (605), Expect = 1.782e-78
Identity = 110/141 (78.01%), Postives = 126/141 (89.36%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+ QET+KK VLKAI   D++Q
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEAQETSKKNVLKAIEQADLLQ 141

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Medaka
Match: zgc:162858 (AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc:101174095])

HSP 1 Score: 237.654 bits (605), Expect = 3.337e-78
Identity = 110/143 (76.92%), Postives = 127/143 (88.81%), Query Frame = 2

Query:   14 YMMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            + MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+ QET+KK VLKAI   D++Q
Sbjct:   19 FQMQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEAQETSKKNVLKAIEQADLLQ 161

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Medaka
Match: zgc:162858 (AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc:101174095])

HSP 1 Score: 238.424 bits (607), Expect = 6.354e-78
Identity = 110/143 (76.92%), Postives = 127/143 (88.81%), Query Frame = 2

Query:   14 YMMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            + MQFMLLFSRQGKLRLQKWY    DK KKKI R+L+  +LARKPKMCSFLEW+D+KIV+KRYASLYFCCA++  +NELI+LE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG+ QET+KK VLKAI   D++Q
Sbjct:   19 FQMQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEAQETSKKNVLKAIEQADLLQ 161

[Close]

BLAST of AP complex subunit sigma vs. Ensembl Medaka
Match: ap1s1 (adaptor related protein complex 1 subunit sigma 1 [Source:NCBI gene;Acc:101154904])

HSP 1 Score: 234.572 bits (597), Expect = 2.570e-77
Identity = 108/142 (76.06%), Postives = 130/142 (91.55%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MM+FMLLFSRQGKLRLQKWYT+  ++ KKK+ R+L+  +LARKPKMCSFLEWKD+KIV+KRYASLYFCCA++  +NELI+LEVIHR+VELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG++Q+T+KK VLKAI   D++Q
Sbjct:    1 MMRFMLLFSRQGKLRLQKWYTATAERDKKKMVRELMQIVLARKPKMCSFLEWKDLKIVYKRYASLYFCCAIEEQDNELITLEVIHRFVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQADLLQ 142

[Close]

BLAST of AP complex subunit sigma vs. Planmine SMEST
Match: SMESG000019676.1 (SMESG000019676.1)

HSP 1 Score: 301.982 bits (772), Expect = 5.212e-104
Identity = 162/162 (100.00%), Postives = 162/162 (100.00%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQXXXXXXXXXXXXXGLMSKSSQ 505
            MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQEESEDSKSLLEELGLMSKSSQ
Sbjct:    1 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQEESEDSKSLLEELGLMSKSSQ 162

[Close]

BLAST of AP complex subunit sigma vs. Planmine SMEST
Match: SMESG000019676.1 (SMESG000019676.1)

HSP 1 Score: 290.426 bits (742), Expect = 1.555e-99
Identity = 141/141 (100.00%), Postives = 141/141 (100.00%), Query Frame = 2

Query:   20 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ
Sbjct:    1 MQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 141

[Close]

BLAST of AP complex subunit sigma vs. Planmine SMEST
Match: SMESG000019676.1 (SMESG000019676.1)

HSP 1 Score: 284.263 bits (726), Expect = 3.974e-97
Identity = 138/138 (100.00%), Postives = 138/138 (100.00%), Query Frame = 2

Query:   29 MLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ
Sbjct:    1 MLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 138

[Close]

BLAST of AP complex subunit sigma vs. Planmine SMEST
Match: SMESG000063235.1 (SMESG000063235.1)

HSP 1 Score: 242.662 bits (618), Expect = 1.223e-80
Identity = 108/142 (76.06%), Postives = 131/142 (92.25%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MMQFMLLFSRQGK+RLQKWY ++ DK +KKI R+L + +L RKPKMC+F+EWKD+KIV++RYASLYFCCAV+R +NEL++LE+IHRYVELLDKYFGSVCELDIIFNFEKAYF+LDEF++ G+VQET+KK VLKA+ AQDMIQ
Sbjct:    1 MMQFMLLFSRQGKVRLQKWYVAHSDKTRKKILRELTSLVLTRKPKMCAFIEWKDLKIVYRRYASLYFCCAVEREDNELVTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFMLDEFMLAGEVQETSKKNVLKAVDAQDMIQ 142

[Close]

BLAST of AP complex subunit sigma vs. Planmine SMEST
Match: SMESG000063235.1 (SMESG000063235.1)

HSP 1 Score: 240.736 bits (613), Expect = 6.966e-80
Identity = 108/142 (76.06%), Postives = 131/142 (92.25%), Query Frame = 2

Query:   17 MMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPKMCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQ 442
            MMQFMLLFSRQGK+RLQKWY ++ DK +KKI R+L + +L RKPKMC+F+EWKD+KIV++RYASLYFCCAV+R +NEL++LE+IHRYVELLDKYFGSVCELDIIFNFEKAYF+LDEF++ G+VQET+KK VLKA+ AQDMIQ
Sbjct:    1 MMQFMLLFSRQGKVRLQKWYVAHSDKTRKKILRELTSLVLTRKPKMCAFIEWKDLKIVYRRYASLYFCCAVEREDNELVTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFMLDEFMLAGEVQETSKKNVLKAVDAQDMIQ 142

The following BLAST results are available for this feature:

BLAST of AP complex subunit sigma vs. Ensembl Human
BLAST of AP complex subunit sigma vs. Ensembl Celegans
BLAST of AP complex subunit sigma vs. Ensembl Fly
BLAST of AP complex subunit sigma vs. Ensembl Zebrafish
BLAST of AP complex subunit sigma vs. Ensembl Xenopus
BLAST of AP complex subunit sigma vs. Ensembl Mouse
BLAST of AP complex subunit sigma vs. UniProt/SwissProt
BLAST of AP complex subunit sigma vs. TrEMBL
BLAST of AP complex subunit sigma vs. Ensembl Cavefish
BLAST of AP complex subunit sigma vs. Ensembl Sea Lamprey
BLAST of AP complex subunit sigma vs. Ensembl Yeast
BLAST of AP complex subunit sigma vs. Ensembl Nematostella
BLAST of AP complex subunit sigma vs. Ensembl Medaka
BLAST of AP complex subunit sigma vs. Planmine SMEST

BLAST of AP complex subunit sigma vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
AP1S2	5.358e-79	78.72	adaptor related protein complex 1 subunit sigma 2 ...	[more]
AP1S2	5.959e-79	78.72	adaptor related protein complex 1 subunit sigma 2 ...	[more]
AP1S2	8.283e-79	78.72	adaptor related protein complex 1 subunit sigma 2 ...	[more]
AP1S2	8.748e-79	78.72	adaptor related protein complex 1 subunit sigma 2 ...	[more]
AP1S2	8.748e-79	78.72	adaptor related protein complex 1 subunit sigma 2 ...	[more]

BLAST of AP complex subunit sigma vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
aps-1	6.692e-85	82.39	AP complex subunit sigma [Source:UniProtKB/TrEMBL...	[more]
aps-2	6.156e-40	45.19	AP complex subunit sigma [Source:UniProtKB/TrEMBL...	[more]
aps-3	1.438e-30	38.51	AdaPtin, Small chain (Clathrin associated complex)...	[more]

BLAST of AP complex subunit sigma vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
AP-1sigma	1.576e-83	80.99	gene:FBgn0039132 transcript:FBtr0305039	[more]
AP-1sigma	1.576e-83	80.99	gene:FBgn0039132 transcript:FBtr0305040	[more]
AP-1sigma	1.807e-83	80.99	gene:FBgn0039132 transcript:FBtr0335244	[more]
AP-1sigma	3.201e-83	80.99	gene:FBgn0039132 transcript:FBtr0084496	[more]
AP-2sigma	1.211e-39	44.44	gene:FBgn0043012 transcript:FBtr0084103	[more]

BLAST of AP complex subunit sigma vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ap1s2	3.982e-78	78.01	adaptor related protein complex 1 subunit sigma 2 ...	[more]
ap1s2	3.982e-78	78.01	adaptor related protein complex 1 subunit sigma 2 ...	[more]
ap1s2	3.982e-78	78.01	adaptor related protein complex 1 subunit sigma 2 ...	[more]
ap1s2	3.982e-78	78.01	adaptor related protein complex 1 subunit sigma 2 ...	[more]
ap1s1	1.850e-77	76.06	adaptor related protein complex 1 subunit sigma 1 ...	[more]

BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tbkbp1	2.464e-78	78.72	TBK1 binding protein 1 [Source:Xenbase;Acc:XB-GENE...	[more]
tbkbp1	3.763e-77	78.17	TBK1 binding protein 1 [Source:Xenbase;Acc:XB-GENE...	[more]
tbkbp1	4.386e-77	78.17	TBK1 binding protein 1 [Source:Xenbase;Acc:XB-GENE...	[more]
plekha3	6.896e-76	75.18	pleckstrin homology domain containing A3 [Source:X...	[more]
plekha3	1.024e-75	75.18	pleckstrin homology domain containing A3 [Source:X...	[more]

BLAST of AP complex subunit sigma vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ap1s2	3.679e-79	78.72	adaptor-related protein complex 1, sigma 2 subunit...	[more]
Ap1s2	4.091e-79	78.72	adaptor-related protein complex 1, sigma 2 subunit...	[more]
Ap1s2	6.204e-79	78.72	adaptor-related protein complex 1, sigma 2 subunit...	[more]
Ap1s1	2.323e-76	75.35	adaptor protein complex AP-1, sigma 1 [Source:MGI ...	[more]
Ap1s1	2.873e-76	75.35	adaptor protein complex AP-1, sigma 1 [Source:MGI ...	[more]

BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9DB50\|AP1S2_MOUSE	2.573e-78	78.72	AP-1 complex subunit sigma-2 OS=Mus musculus OX=10...	[more]
sp\|Q3ZBS3\|AP1S2_BOVIN	2.573e-78	78.72	AP-1 complex subunit sigma-2 OS=Bos taurus OX=9913...	[more]
sp\|P56377\|AP1S2_HUMAN	2.862e-78	78.72	AP-1 complex subunit sigma-2 OS=Homo sapiens OX=96...	[more]
sp\|P61967\|AP1S1_MOUSE	2.009e-75	75.35	AP-1 complex subunit sigma-1A OS=Mus musculus OX=1...	[more]
sp\|P61966\|AP1S1_HUMAN	2.009e-75	75.35	AP-1 complex subunit sigma-1A OS=Homo sapiens OX=9...	[more]

BLAST of AP complex subunit sigma vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2C9M9V4	4.458e-82	82.39	AP complex subunit sigma OS=Biomphalaria glabrata ...	[more]
A0A2C9M9V9	4.692e-82	82.39	AP complex subunit sigma OS=Biomphalaria glabrata ...	[more]
A0A2C9M9V0	5.912e-82	82.39	AP complex subunit sigma OS=Biomphalaria glabrata ...	[more]
A0A3P7M6W9	7.048e-82	83.80	AP complex subunit sigma OS=Cylicostephanus goldi ...	[more]
G0MXN1	7.124e-82	83.10	AP complex subunit sigma OS=Caenorhabditis brenner...	[more]

BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
AP1S2	1.164e-78	78.01	AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc...	[more]
AP1S2	3.810e-78	78.01	AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc...	[more]
ap1s1	1.173e-76	75.89	AP-1 complex subunit sigma-1A [Source:NCBI gene;Ac...	[more]
ENSAMXT00000055261.1	6.071e-72	69.01	AP-1 complex subunit sigma-2-like [Source:NCBI gen...	[more]
ENSAMXT00000046966.1	2.169e-71	75.76	pep primary_assembly:Astyanax_mexicanus-2.0:5:1503...	[more]

BLAST of AP complex subunit sigma vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ap2s1	3.571e-40	44.44	adaptor related protein complex 2 subunit sigma 1 ...	[more]
ap3s2	8.002e-30	39.19	adaptor related protein complex 3 subunit sigma 2 ...	[more]

BLAST of AP complex subunit sigma vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4


Match Name	E-value	Identity	Description
APS1	1.808e-49	51.75	Small subunit of the clathrin-associated adaptor c...	[more]
APS2	1.811e-33	44.44	Small subunit of the clathrin-associated adaptor c...	[more]
APS3	3.255e-16	31.17	Small subunit of the clathrin-associated adaptor c...	[more]
YLR171W_mRNA	3.269e-10	42.45	Dubious open reading frame; unlikely to encode a f...	[more]

BLAST of AP complex subunit sigma vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO45252	8.743e-77	76.98	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38137	5.525e-40	45.39	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42183	1.703e-38	42.96	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42407	5.894e-31	35.68	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of AP complex subunit sigma vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
AP1S2	1.852e-79	79.43	AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc...	[more]
zgc:162858	1.782e-78	78.01	AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc...	[more]
zgc:162858	3.337e-78	76.92	AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc...	[more]
zgc:162858	6.354e-78	76.92	AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc...	[more]
ap1s1	2.570e-77	76.06	adaptor related protein complex 1 subunit sigma 1 ...	[more]

BLAST of AP complex subunit sigma vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000019676.1	5.212e-104	100.00	SMESG000019676.1	[more]
SMESG000019676.1	1.555e-99	100.00	SMESG000019676.1	[more]
SMESG000019676.1	3.974e-97	100.00	SMESG000019676.1	[more]
SMESG000063235.1	1.223e-80	76.06	SMESG000063235.1	[more]
SMESG000063235.1	6.966e-80	76.06	SMESG000063235.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30005038 ID=SMED30005038|Name=AP complex subunit sigma|organism=Schmidtea mediterranea sexual|type=transcript|length=996bp
TCTATATAAATCTTATATGATGCAATTTATGCTATTATTTAGTCGACAAG
GTAAACTTCGACTGCAAAAATGGTATACGTCATATCCAGATAAAGTTAAA
AAGAAAATCGCTAGGGACTTAATTGCGCAAATTCTTGCAAGAAAACCAAA
AATGTGTTCATTTTTAGAATGGAAAGATATGAAAATTGTATTTAAGAGGT
ACGCAAGTCTTTATTTTTGTTGTGCAGTTGATAGAACAGAAAATGAATTA
ATATCCTTGGAGGTTATACATAGATATGTAGAATTATTGGATAAATATTT
CGGAAGTGTGTGTGAGTTAGATATAATTTTCAATTTTGAAAAAGCATATT
TCATTCTGGATGAATTTCTTATTGGTGGTCAAGTTCAAGAAACGAACAAG
AAAATGGTTCTCAAAGCAATTTCAGCCCAAGATATGATACAAGAGGAATC
TGAAGATAGCAAAAGCCTACTTGAAGAATTGGGATTGATGTCGAAAAGCT
CTCAGTGAATTACTATTGTTTGCAATTATTTAACAGTATTATCGAGGTTG
TCTTTGGGATAGGTTATATATTTATTAAATTATGTAAAGTGTCATTTAAT
CATTGAGTCTTCCTAATTGTATAATTATTCACTATTCAATTTGTGATTAG
ATTTGCTCTGTACAATTTGTGGGATAATATCGTTTAATTTGCTTGTAAAT
GTTTTGTTGATTGGGAATTTTGTTTTTTGTTAGAGGTTGTTTTTATTCAA
TTGGCTTGTTTGATTGATGAATATATACATTTATCTATGCATTTTTTAAT
TGGATCACTTTATTATATTTCCCGTCGGAATAGATAGTTTGGTTCCAATA
AAATAGTTAATTTTATTATTATTTTTATCAACTTATTGTTGTAACTCATT
TGTACGCAGAGCAAGTATAAATTCATCATCATATATACAGTCGTTACCAC
CAGAACTATGTATTTAGGCTACTCCATTTATCCATCTCAATATATA

protein sequence of SMED30005038-orf-1

>SMED30005038-orf-1 ID=SMED30005038-orf-1|Name=SMED30005038-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=169bp
LYKSYMMQFMLLFSRQGKLRLQKWYTSYPDKVKKKIARDLIAQILARKPK
MCSFLEWKDMKIVFKRYASLYFCCAVDRTENELISLEVIHRYVELLDKYF
GSVCELDIIFNFEKAYFILDEFLIGGQVQETNKKMVLKAISAQDMIQEES
EDSKSLLEELGLMSKSSQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0030117	membrane coat

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000028	Category 2 cell
PLANA:0000140	anterior region of the whole animal
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR016635	AP_complex_ssu
IPR022775	AP_mu_sigma_su
IPR011012	Longin-like_dom_sf

Vocabulary: **biological process**
Term	Definition
GO:0015031	protein transport
GO:0006810	transport
GO:0006886	intracellular protein transport
GO:0016192	vesicle-mediated transport

Vocabulary: **molecular function**
Term	Definition
GO:0008565	protein transporter activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	G3DSA:3.30.450.60		coord: 1..157 e-value: 1.1E-61 score: 209.1
None	No IPR available	PANTHER	PTHR11753:SF45	AP-1 COMPLEX SUBUNIT SIGMA-2	coord: 1..152
None	No IPR available	CDD	cd14831	AP1_sigma	coord: 2..144 e-value: 5.76109E-98 score: 276.747
IPR016635	Adaptor protein complex, sigma subunit	PIRSF	PIRSF015588	AP_complex_sigma	coord: 1..151 e-value: 1.7E-66 score: 220.4
IPR016635	Adaptor protein complex, sigma subunit	PANTHER	PTHR11753	CLATHRIN COAT ASSEMBLY PROTEIN	coord: 1..152
IPR022775	AP complex, mu/sigma subunit	PFAM	PF01217	Clat_adaptor_s	coord: 1..139 e-value: 9.9E-58 score: 194.1
IPR011012	Longin-like domain superfamily	SUPERFAMILY	SSF64356	SNARE-like	coord: 2..139