BHLH domain-containing protein

Overview
NameBHLH domain-containing protein
Smed IDSMED30005025
Length (bp)1021
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of BHLH domain-containing protein (SMED30005025) t-SNE clustered cells

Violin plots show distribution of expression levels for BHLH domain-containing protein (SMED30005025) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of BHLH domain-containing protein (SMED30005025) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for BHLH domain-containing protein (SMED30005025) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30005025

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30005025h1SMcG0002524 SmedASXL_007865SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30005025h1SMcG0002524 dd_Smed_v6_28567_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
progenitor cellSMED30005025h1SMcG0002524 KF487103smed_ncbi_20240424PMID:24173799
Cowles et al., 2013		whole organism asexual adult colorimetric in situ hybridization evidence
stem cellSMED30005025h1SMcG0002524 KF487103smed_ncbi_20240424PMID:24173799
Cowles et al., 2013		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30005025h1SMcG0002524 KF487103smed_ncbi_20240424PMID:24173799
Cowles et al., 2013		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Human
Match: PTF1A (pancreas associated transcription factor 1a [Source:HGNC Symbol;Acc:HGNC:23734])

HSP 1 Score: 80.8777 bits (198), Expect = 1.456e-16
Identity = 37/55 (67.27%), Postives = 43/55 (78.18%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  ANVRER R+ SIN AF  LRS +PT PYE+RLSK+DTLRLAI YI+ L +LV
Sbjct:  165 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELV 219
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Human
Match: FERD3L (Fer3 like bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:16660])

HSP 1 Score: 74.3294 bits (181), Expect = 2.502e-15
Identity = 37/73 (50.68%), Postives = 51/73 (69.86%), Query Frame = 2 
Query:  587 APRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDS 805
            A R  AN+RER R+ ++N AF +LR +VPTF YE+RLS+I+TLRLAI YIS + +L+        E+CE  +S
Sbjct:  101 AQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELL--------ESCEKKES 165
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Human
Match: SCX (scleraxis bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:32322])

HSP 1 Score: 67.781 bits (164), Expect = 9.332e-13
Identity = 34/66 (51.52%), Postives = 46/66 (69.70%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENC 790
            R+ AN RER+R  S+NTAF  LR+ +PT P +R+LSKI+TLRLA +YIS L +++      A E C
Sbjct:   77 RHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLL-----AGEAC 137
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Human
Match: HAND2 (heart and neural crest derivatives expressed 2 [Source:HGNC Symbol;Acc:HGNC:4808])

HSP 1 Score: 64.6994 bits (156), Expect = 1.321e-11
Identity = 31/55 (56.36%), Postives = 39/55 (70.91%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  AN +ER R  SIN+AFAELR  +P  P + +LSKI TLRLA +YI+ L DL+
Sbjct:  101 RGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLL 155
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Human
Match: HAND2 (heart and neural crest derivatives expressed 2 [Source:HGNC Symbol;Acc:HGNC:4808])

HSP 1 Score: 64.3142 bits (155), Expect = 1.337e-11
Identity = 35/81 (43.21%), Postives = 47/81 (58.02%), Query Frame = 2 
Query:  524 NTWNISDYTFTYQNPSTMFDEAPRYV---ANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            + W I     +  + S     +P Y    AN +ER R  SIN+AFAELR  +P  P + +LSKI TLRLA +YI+ L DL+
Sbjct:   44 HGWLIGHPEMSPPDYSMALSYSPEYASGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLL 124
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Celegans
Match: hlh-13 (Helix-loop-helix protein 13 [Source:UniProtKB/Swiss-Prot;Acc:Q20561])

HSP 1 Score: 95.9005 bits (237), Expect = 7.185e-24
Identity = 54/117 (46.15%), Postives = 72/117 (61.54%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQV---TWFTSDLITRLSWINWDKLGCQEPL 934
            R  A++RER R+ SIN AF ELR+ +PTFPYE+RLSKIDTL LAIAYI++L D++            P DS    ++   +      Q+    W TSDL+ RL+WI W +LG  EP+
Sbjct:   43 RQTASIRERKRMCSINVAFIELRNYIPTFPYEKRLSKIDTLNLAIAYINMLDDVLR----------TPEDS--GQYIQKCVHMARTGQIGAPAWSTSDLLARLNWIKWRRLGI-EPI 146
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Celegans
Match: hlh-15 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q18590])

HSP 1 Score: 61.2326 bits (147), Expect = 7.287e-12
Identity = 34/87 (39.08%), Postives = 53/87 (60.92%), Query Frame = 2 
Query:  503 NINSTSENTWNISDYTFTYQNPSTMFDEAPRY--VANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
             +++TSE    +S      +  +T     P+Y  +   RER R+ S N AF++LR+ +PT P E++LSKI+ LR +IAYIS L +L+
Sbjct:    7 GLDTTSEEYRKLSKAERRKRRRAT-----PKYRNLHATRERIRVESFNMAFSQLRALLPTLPVEKKLSKIEILRFSIAYISFLDNLL 88
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Celegans
Match: lin-32 (pep chromosome:WBcel235:X:2229208:2230122:-1 gene:WBGene00003018.1 transcript:T14F9.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-32)

HSP 1 Score: 50.447 bits (119), Expect = 1.514e-7
Identity = 25/67 (37.31%), Postives = 38/67 (56.72%), Query Frame = 2 
Query:  557 YQNPSTMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            Y+ PS       R  AN RER R+ ++N A+ ELR  +P     ++LSK +TL++A  YI  L  ++
Sbjct:   62 YKTPSPQLLRMRRSAANERERRRMNTLNVAYDELREVLPEIDSGKKLSKFETLQMAQKYIECLSQIL 128
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Celegans
Match: hlh-8 (Twist-related protein [Source:UniProtKB/Swiss-Prot;Acc:Q11094])

HSP 1 Score: 49.6766 bits (117), Expect = 4.135e-7
Identity = 25/54 (46.30%), Postives = 34/54 (62.96%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDL 754
            R  AN RER R   +N AF  LR  +P+ P ++ +SKI TLR+A  YIS L ++
Sbjct:   22 RACANRRERQRTKELNDAFTLLRKLIPSMPSDK-MSKIHTLRIATDYISFLDEM 74
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Celegans
Match: hlh-6 (Helix-loop-helix protein 6 [Source:UniProtKB/Swiss-Prot;Acc:Q10007])

HSP 1 Score: 50.8322 bits (120), Expect = 4.302e-7
Identity = 28/63 (44.44%), Postives = 40/63 (63.49%), Query Frame = 2 
Query:  605 NVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCE 793
            N RER R+ ++N  +  LR  +P    E+R+SK+DTLRLAI YI  L +L+   + H Y NC+
Sbjct:  179 NERERCRVRNVNDGYERLRKHLPVHFDEKRISKVDTLRLAIRYIKHLDNLLRS-ELHQY-NCK 239
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Fly
Match: Fer2 (gene:FBgn0038402 transcript:FBtr0301709)

HSP 1 Score: 102.834 bits (255), Expect = 3.731e-25
Identity = 61/110 (55.45%), Postives = 73/110 (66.36%), Query Frame = 2 
Query:  593 RYVANVRERNRIMS-INTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTWFTSDLITRLSWINWDKLG 919
            R  ANVRER RI S IN+AF ELR  VPTFPYE+RLSKIDTLRLAIAYISLL++++         + +P  + ++  L   I  D  N   W TSDL  RLSWINW+ LG
Sbjct:  149 RQAANVRERKRIQSSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVL-------QTDYDP-LTYVEKCLRGEIKADRAN---WNTSDLTARLSWINWENLG 247
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Fly
Match: Fer2 (gene:FBgn0038402 transcript:FBtr0344010)

HSP 1 Score: 100.908 bits (250), Expect = 2.084e-24
Identity = 61/115 (53.04%), Postives = 73/115 (63.48%), Query Frame = 2 
Query:  593 RYVANVRERNRIM------SINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTWFTSDLITRLSWINWDKLG 919
            R  ANVRER RI       SIN+AF ELR  VPTFPYE+RLSKIDTLRLAIAYISLL++++         + +P  + ++  L   I  D  N   W TSDL  RLSWINW+ LG
Sbjct:  149 RQAANVRERKRIQRSAPTGSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVL-------QTDYDP-LTYVEKCLRGEIKADRAN---WNTSDLTARLSWINWENLG 252
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Fly
Match: Fer2 (gene:FBgn0038402 transcript:FBtr0344011)

HSP 1 Score: 99.7525 bits (247), Expect = 7.405e-24
Identity = 61/119 (51.26%), Postives = 73/119 (61.34%), Query Frame = 2 
Query:  593 RYVANVRERNRI----------MSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTWFTSDLITRLSWINWDKLG 919
            R  ANVRER RI           SIN+AF ELR  VPTFPYE+RLSKIDTLRLAIAYISLL++++         + +P  + ++  L   I  D  N   W TSDL  RLSWINW+ LG
Sbjct:  149 RQAANVRERKRIQRSAPTGYTKCSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVLQ-------TDYDP-LTYVEKCLRGEIKADRAN---WNTSDLTARLSWINWENLG 256
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Fly
Match: Fer2 (gene:FBgn0038402 transcript:FBtr0344012)

HSP 1 Score: 94.3597 bits (233), Expect = 4.499e-22
Identity = 59/110 (53.64%), Postives = 72/110 (65.45%), Query Frame = 2 
Query:  593 RYVANVRERNRIMS-INTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTWFTSDLITRLSWINWDKLG 919
            R  ANVRER RI S IN+AF ELR  VPTFPYE+RLSKIDTLRLAIAYISLL++++         + +P  + ++  L   I  D  N   W T +L  RLSWINW+ LG
Sbjct:  149 RQAANVRERKRIQSSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVL-------QTDYDP-LTYVEKCLRGEIKADRAN---WNT-NLTARLSWINWENLG 246
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Fly
Match: Fer1 (gene:FBgn0037475 transcript:FBtr0081567)

HSP 1 Score: 80.4925 bits (197), Expect = 3.332e-17
Identity = 45/106 (42.45%), Postives = 62/106 (58.49%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDH----ILNDNRNQVTWFTSDLITRLSW 898
            R  AN+RER R+ SIN AF  LR+ +PT PYE+RLSK+DTL+LAI+YI+ L ++V   +N      EP  S+ +N+  +     IL D        T  +   LSW
Sbjct:   83 RQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITFLSEMVKKDKN----GNEPGLSLQRNYQKEPPKKIILKDR-------TGGVAHSLSW 177
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-34f9.3 (si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-410])

HSP 1 Score: 111.694 bits (278), Expect = 1.989e-29
Identity = 57/108 (52.78%), Postives = 75/108 (69.44%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQ--VTWFTSDLITRLSWINWD 910
            R+ AN+RER R++SIN+AF ELR  VPTFPYE+RLSKIDTLRLAIAYI+LL++++          C+P     K+++ + + N  +NQ    W TSDL  RLSWI WD
Sbjct:   67 RHAANIRERKRMLSINSAFEELRCHVPTFPYEKRLSKIDTLRLAIAYIALLREIL-------LSGCDP-----KSYVDECMKNGYKNQTNAIWNTSDLTARLSWIKWD 162
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Zebrafish
Match: ptf1a (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:368662])

HSP 1 Score: 80.1073 bits (196), Expect = 7.070e-17
Identity = 37/55 (67.27%), Postives = 43/55 (78.18%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  ANVRER R+ SIN AF  LRS +PT PYE+RLSK+DTLRLAI YI+ L +LV
Sbjct:  117 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELV 171
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Zebrafish
Match: ferd3l (Fer3-like bHLH transcription factor [Source:ZFIN;Acc:ZDB-GENE-081104-461])

HSP 1 Score: 72.4034 bits (176), Expect = 7.783e-16
Identity = 33/55 (60.00%), Postives = 43/55 (78.18%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  AN+RER R+ S+N AF  LR RVPTF YE+RLS+I+TLRLAI YI+ + D++
Sbjct:   26 RQAANIRERKRMFSLNEAFDRLRRRVPTFAYEKRLSRIETLRLAIVYIAFMTDIL 80
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-246m6.4 (si:ch211-246m6.4 [Source:ZFIN;Acc:ZDB-GENE-050208-498])

HSP 1 Score: 69.707 bits (169), Expect = 1.136e-13
Identity = 34/74 (45.95%), Postives = 47/74 (63.51%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIK 814
            R  AN RER+R  S+NTAF  LR+ +PT P +R+LSKI+TLRLA +YIS L +++        E+C      +K
Sbjct:   85 RQAANARERDRTHSVNTAFTSLRTLIPTEPADRKLSKIETLRLASSYISHLANVLLLG-----EDCRDGQPCLK 153
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Zebrafish
Match: tcf15 (transcription factor 15 [Source:ZFIN;Acc:ZDB-GENE-980605-20])

HSP 1 Score: 67.781 bits (164), Expect = 3.820e-13
Identity = 38/94 (40.43%), Postives = 54/94 (57.45%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTWFTS 874
            R  AN RER+R  S+NTAF  LR+ +PT P +R+LSKI+TLRLA +YIS L +++        E+ +P  S + +   D      R   T+  S
Sbjct:   66 RNAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYISHLANVLLI--GDGGEDAQPCVSAVYSAQGDSGGKQPRTICTFCLS 157
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000031930.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:9:55646956:55647657:1 gene:ENSXETG00000008961.1 transcript:ENSXETT00000031930.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 92.0485 bits (227), Expect = 8.225e-22
Identity = 46/72 (63.89%), Postives = 56/72 (77.78%), Query Frame = 2 
Query:  554 TYQNPSTMFDEAP----RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            ++Q  S M  E P    R  AN+RER R++SIN+AF ELR RVPTFPYE+RLSKIDTLRLAIAYI+LL D++
Sbjct:   70 SFQEESLM--EGPCKVHRQAANIRERRRMLSINSAFEELRGRVPTFPYEKRLSKIDTLRLAIAYIALLSDIL 139
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Xenopus
Match: PTF1A (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:100494161])

HSP 1 Score: 80.1073 bits (196), Expect = 2.168e-16
Identity = 37/55 (67.27%), Postives = 43/55 (78.18%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  ANVRER R+ SIN AF  LRS +PT PYE+RLSK+DTLRLAI YI+ L +LV
Sbjct:  171 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELV 225
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Xenopus
Match: ferd3l (Fer3-like bHLH transcription factor [Source:NCBI gene;Acc:100124312])

HSP 1 Score: 70.4774 bits (171), Expect = 2.351e-14
Identity = 32/57 (56.14%), Postives = 44/57 (77.19%), Query Frame = 2 
Query:  587 APRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            A R  AN+RER R+ ++N AF  LR +VPTF YE+RLS+I+TLRLAI YIS + +++
Sbjct:   65 AQRQAANIRERKRMFNLNEAFDLLRKKVPTFAYEKRLSRIETLRLAIVYISFMTEML 121
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Xenopus
Match: adra1d (adrenoceptor alpha 1D [Source:Xenbase;Acc:XB-GENE-6050827])

HSP 1 Score: 68.9366 bits (167), Expect = 4.189e-13
Identity = 31/60 (51.67%), Postives = 44/60 (73.33%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQN 772
            R  AN RER+R  S+NTAF  LR+ +PT P +R+LSKI+TLRLA +YIS L +++   ++
Sbjct:  104 RQAANARERDRTHSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLANILLLGED 163
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Xenopus
Match: tcf15 (transcription factor 15 [Source:NCBI gene;Acc:549260])

HSP 1 Score: 67.3958 bits (163), Expect = 5.517e-13
Identity = 31/60 (51.67%), Postives = 43/60 (71.67%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQN 772
            R  AN RER+R  S+NTAF  LR+ +PT P +R+LSKI+TLRLA +YIS L +++   + 
Sbjct:   64 RQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYISHLANVLLLGEG 123
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Mouse
Match: Ptf1a (pancreas specific transcription factor, 1a [Source:MGI Symbol;Acc:MGI:1328312])

HSP 1 Score: 80.8777 bits (198), Expect = 9.702e-17
Identity = 37/55 (67.27%), Postives = 43/55 (78.18%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  ANVRER R+ SIN AF  LRS +PT PYE+RLSK+DTLRLAI YI+ L +LV
Sbjct:  162 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELV 216
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Mouse
Match: Ferd3l (Fer3 like bHLH transcription factor [Source:MGI Symbol;Acc:MGI:2150010])

HSP 1 Score: 72.0182 bits (175), Expect = 1.195e-14
Identity = 33/57 (57.89%), Postives = 45/57 (78.95%), Query Frame = 2 
Query:  587 APRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            A R  AN+RER R+ ++N AF +LR +VPTF YE+RLS+I+TLRLAI YIS + +L+
Sbjct:  103 AQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELL 159
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Mouse
Match: Scx (scleraxis [Source:MGI Symbol;Acc:MGI:102934])

HSP 1 Score: 67.781 bits (164), Expect = 8.275e-13
Identity = 31/59 (52.54%), Postives = 44/59 (74.58%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQ 769
            R+ AN RER+R  S+NTAF  LR+ +PT P +R+LSKI+TLRLA +YIS L +++   +
Sbjct:   80 RHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLVGE 138
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Mouse
Match: Tcf15 (transcription factor 15 [Source:MGI Symbol;Acc:MGI:104664])

HSP 1 Score: 65.4698 bits (158), Expect = 4.439e-12
Identity = 32/68 (47.06%), Postives = 47/68 (69.12%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEP 796
            R  AN RER+R  S+NTAF  LR+ +PT P +R+LSKI+TLRLA +YI+ L +++      A ++ +P
Sbjct:   72 RQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLL--GDAADDGQP 137
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Mouse
Match: Hand2 (heart and neural crest derivatives expressed 2 [Source:MGI Symbol;Acc:MGI:103580])

HSP 1 Score: 64.6994 bits (156), Expect = 9.069e-12
Identity = 31/55 (56.36%), Postives = 39/55 (70.91%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  AN +ER R  SIN+AFAELR  +P  P + +LSKI TLRLA +YI+ L DL+
Sbjct:  101 RGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLL 155
[Close]
BLAST of BHLH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q20561|HLH13_CAEEL (Helix-loop-helix protein 13 OS=Caenorhabditis elegans OX=6239 GN=hlh-13 PE=2 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 9.140e-23
Identity = 54/117 (46.15%), Postives = 72/117 (61.54%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQV---TWFTSDLITRLSWINWDKLGCQEPL 934
            R  A++RER R+ SIN AF ELR+ +PTFPYE+RLSKIDTL LAIAYI++L D++            P DS    ++   +      Q+    W TSDL+ RL+WI W +LG  EP+
Sbjct:   43 RQTASIRERKRMCSINVAFIELRNYIPTFPYEKRLSKIDTLNLAIAYINMLDDVLR----------TPEDS--GQYIQKCVHMARTGQIGAPAWSTSDLLARLNWIKWRRLGI-EPI 146
[Close]
BLAST of BHLH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7ZSX3|PTF1A_DANRE (Pancreas transcription factor 1 subunit alpha OS=Danio rerio OX=7955 GN=ptf1a PE=2 SV=1)

HSP 1 Score: 80.1073 bits (196), Expect = 5.337e-16
Identity = 37/55 (67.27%), Postives = 43/55 (78.18%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  ANVRER R+ SIN AF  LRS +PT PYE+RLSK+DTLRLAI YI+ L +LV
Sbjct:  117 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELV 171
[Close]
BLAST of BHLH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q64305|PTF1A_RAT (Pancreas transcription factor 1 subunit alpha OS=Rattus norvegicus OX=10116 GN=Ptf1a PE=1 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 6.052e-16
Identity = 37/55 (67.27%), Postives = 43/55 (78.18%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  ANVRER R+ SIN AF  LRS +PT PYE+RLSK+DTLRLAI YI+ L +LV
Sbjct:  164 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELV 218
[Close]
BLAST of BHLH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9QX98|PTF1A_MOUSE (Pancreas transcription factor 1 subunit alpha OS=Mus musculus OX=10090 GN=Ptf1a PE=1 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 6.786e-16
Identity = 37/55 (67.27%), Postives = 43/55 (78.18%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  ANVRER R+ SIN AF  LRS +PT PYE+RLSK+DTLRLAI YI+ L +LV
Sbjct:  162 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELV 216
[Close]
BLAST of BHLH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7RTS3|PTF1A_HUMAN (Pancreas transcription factor 1 subunit alpha OS=Homo sapiens OX=9606 GN=PTF1A PE=1 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 6.993e-16
Identity = 37/55 (67.27%), Postives = 43/55 (78.18%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  ANVRER R+ SIN AF  LRS +PT PYE+RLSK+DTLRLAI YI+ L +LV
Sbjct:  165 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELV 219
[Close]
BLAST of BHLH domain-containing protein vs. TrEMBL
Match: U5YQC9 (Ptf-3 protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=ptf-3 PE=2 SV=1)

HSP 1 Score: 180.259 bits (456), Expect = 1.529e-53
Identity = 86/86 (100.00%), Postives = 86/86 (100.00%), Query Frame = 2 
Query:  551 FTYQNPSTMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSI 808
            FTYQNPSTMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSI
Sbjct:    1 FTYQNPSTMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSI 86
[Close]
BLAST of BHLH domain-containing protein vs. TrEMBL
Match: A0A4Z2CRU7 (Helix-loop-helix protein OS=Schistosoma japonicum OX=6182 GN=EWB00_008144 PE=4 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 3.144e-29
Identity = 62/150 (41.33%), Postives = 101/150 (67.33%), Query Frame = 2 
Query:  503 NINSTSENTWNISDYTFTYQNPSTMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTWFTSDLITRLSWINWDKLGCQEPLEFSHTL 952
            N+ +   + ++I++ +++ Q    +FD+  + VA VRER R+ SIN+AF  LRS +PTFPYERR+SKIDTLRLAIAY++LL+DL+   +    +        +  F++  + +  R+ ++W+TSDLI RL+WI WD+LG +  +++S +L
Sbjct:  122 NLKTIHNDVFDITNESYS-QYIQRVFDKDFQSVAKVRERKRMFSINSAFEALRSCLPTFPYERRISKIDTLRLAIAYLALLKDLLANLEMMDTDQTVRRGQRVIQFMIKRLNSSKRHHLSWYTSDLIARLNWIRWDRLGYRGTIDWSSSL 270
[Close]
BLAST of BHLH domain-containing protein vs. TrEMBL
Match: A0A2C9M578 (BHLH domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106060447 PE=4 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 1.000e-28
Identity = 66/148 (44.59%), Postives = 86/148 (58.11%), Query Frame = 2 
Query:  548 TFTYQNP--------STMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTWFTSDLITRLSWINWDKLGCQEPLEFSHTLPFTNK 967
            +F YQ+P        S  +   PR  ANVRER R+MSIN AF ELR  VPTFP+E+RLSKIDTLRLAIAYI+LL+D++           +P +     F+   I     N   W TSDL++RLSW+ W+ LG +    +S + P   K
Sbjct:   79 SFGYQDPHDATNSYCSFQYGGVPRAAANVRERKRMMSINGAFEELRLHVPTFPFEKRLSKIDTLRLAIAYIALLRDIL-------VSGTDPLE-----FVEASIHGRKENHSEWNTSDLMSRLSWVRWENLGARRYGAYSSSQPGHRK 214
[Close]
BLAST of BHLH domain-containing protein vs. TrEMBL
Match: A0A430QCS1 (BHLH domain-containing protein OS=Schistosoma bovis OX=6184 GN=DC041_0000483 PE=4 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 6.556e-28
Identity = 59/126 (46.83%), Postives = 88/126 (69.84%), Query Frame = 2 
Query:  575 MFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTWFTSDLITRLSWINWDKLGCQEPLEFSHTL 952
            +FD+  +  A VRER R+ SIN+AF  LRS +PTFPYERR+SKIDTLRLAIAY++LL+DL+   +    E       ++  F++  + +  R+Q++W+TSDLI RL+WI WD+LG    +++S ++
Sbjct:  124 VFDKDFQSYAKVRERRRMFSINSAFEALRSCLPTFPYERRISKIDTLRLAIAYLALLKDLLANMEIINPEQNIERGQLVIQFMIKRLNSSKRHQLSWYTSDLIARLNWIRWDRLGYSGTIDWSSSI 249
[Close]
BLAST of BHLH domain-containing protein vs. TrEMBL
Match: A0A5K4FAF3 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 7.126e-28
Identity = 70/180 (38.89%), Postives = 116/180 (64.44%), Query Frame = 2 
Query:  404 FNICMEINSTFRMNEEI----YNYKNIDMYGQYKSMININ----STSENTWNISDYTFTYQNPSTMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTWFTSDLITRLSWINWDKLG 919
            FN+ +E N+TFR+   +    ++ +N D       + +IN    ++ ++  NI++ + + +    ++++  + VA VRER R+ SIN+AF  LRS +PTFPYERR+SKIDTLRLAIAY++LL+DL+   +    E       ++  F+++ + +  R+Q++W+TSDLI RL+WI WD+LG
Sbjct:   76 FNLGLE-NNTFRLQNTLENMNFSLQNNDTRICNTELFDINDNLKTSHDDILNITNESCS-EYIHNVYNKDFQSVAKVRERRRMFSINSAFEALRSCLPTFPYERRISKIDTLRLAIAYLALLKDLLANMEIMNAEQDIERGQLVIQFMINRLNSSQRHQLSWYTSDLIARLNWIRWDRLG 253
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Cavefish
Match: si:dkey-34f9.3 (neurogenic differentiation factor 1-like [Source:NCBI gene;Acc:107197807])

HSP 1 Score: 109.768 bits (273), Expect = 3.181e-28
Identity = 56/108 (51.85%), Postives = 75/108 (69.44%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQ--VTWFTSDLITRLSWINWD 910
            R+ AN+RER R++SIN+AF +LR  VPTFPYE+RLSKIDTLRLAIAYI+LL++++          C+P     K+++ + + N  +NQ    W TSDL  RLSWI WD
Sbjct:  122 RHAANIRERKRMLSINSAFEQLRCHVPTFPYEKRLSKIDTLRLAIAYIALLREIL-------MSGCDP-----KSYVDECMKNGYKNQTNAIWNTSDLTARLSWIKWD 217
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Cavefish
Match: ferd3l (Fer3-like bHLH transcription factor [Source:ZFIN;Acc:ZDB-GENE-081104-461])

HSP 1 Score: 74.7146 bits (182), Expect = 6.824e-17
Identity = 34/54 (62.96%), Postives = 43/54 (79.63%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDL 754
            R  AN+RER R+ S+N AF ELR +VPTF YE+RLS+I+TLRLAI YIS + +L
Sbjct:   17 RQAANIRERKRMFSLNEAFDELRKKVPTFAYEKRLSRIETLRLAIVYISFMTEL 70
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Cavefish
Match: ptf1a (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:103046795])

HSP 1 Score: 79.337 bits (194), Expect = 9.353e-17
Identity = 37/55 (67.27%), Postives = 43/55 (78.18%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  ANVRER R+ SIN AF  LRS +PT PYE+RLSK+DTLRLAI YI+ L +LV
Sbjct:   94 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELV 148
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Cavefish
Match: scxa (scleraxis bHLH transcription factor a [Source:ZFIN;Acc:ZDB-GENE-060503-414])

HSP 1 Score: 69.3218 bits (168), Expect = 1.226e-13
Identity = 34/70 (48.57%), Postives = 46/70 (65.71%), Query Frame = 2 
Query:  566 PSTMFDEA-PRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQN 772
            P  M  E   R  AN RER+R  S+NTAF  LR+ +PT P +R+LSKI+TLRLA +YIS L +++   + 
Sbjct:   70 PGPMLGEGRQRNAANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLVGEG 139
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Cavefish
Match: tcf15 (transcription factor 15 [Source:NCBI gene;Acc:103040145])

HSP 1 Score: 67.781 bits (164), Expect = 3.475e-13
Identity = 34/68 (50.00%), Postives = 47/68 (69.12%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEP 796
            R  AN RER+R  S+NTAF  LR+ +PT P +R+LSKI+TLRLA +YIS L +++      A E+ +P
Sbjct:   63 RNAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYISHLANVL--LTGDAGEHAQP 128
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Sea Lamprey
Match: si:dkey-34f9.3 (si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-410])

HSP 1 Score: 103.99 bits (258), Expect = 1.003e-27
Identity = 56/108 (51.85%), Postives = 69/108 (63.89%), Query Frame = 2 
Query:  584 EAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTWFTSDLITRLSWINW 907
            E  R  ANVRER R++SIN+AF ELR  VPTFPYE+RLSKIDTLRLAIAYI+LL+D++         + +P   + +     H    N +   W TSDL  RLSWI W
Sbjct:   32 EVQRTAANVRERRRMLSINSAFEELRCHVPTFPYEKRLSKIDTLRLAIAYIALLRDIL-------LSDTDPKAYVDRCIRKGH---PNSSNALWNTSDLTARLSWIKW 129
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004072.1 (pep scaffold:Pmarinus_7.0:GL492732:1750:4325:-1 gene:ENSPMAG00000003727.1 transcript:ENSPMAT00000004072.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 80.1073 bits (196), Expect = 1.270e-17
Identity = 36/55 (65.45%), Postives = 42/55 (76.36%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  AN RER R+ SIN AF  LR+ +PT PYE+RLSK+DTLRLAI YIS L +LV
Sbjct:  133 RQAANQRERRRMQSINAAFEGLRAHIPTLPYEKRLSKVDTLRLAIGYISFLGELV 187
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Sea Lamprey
Match: scxa (scleraxis bHLH transcription factor a [Source:ZFIN;Acc:ZDB-GENE-060503-414])

HSP 1 Score: 59.3066 bits (142), Expect = 3.933e-11
Identity = 27/51 (52.94%), Postives = 38/51 (74.51%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLL 745
            R  AN RER+R  S+N+AF  LR+ +PT P +R+LSK++TL LA +YI+ L
Sbjct:   38 RRAANARERDRTQSVNSAFTALRTLIPTEPADRKLSKLETLLLASSYIAHL 88
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Sea Lamprey
Match: TWIST1 (twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428])

HSP 1 Score: 60.077 bits (144), Expect = 4.335e-11
Identity = 30/51 (58.82%), Postives = 36/51 (70.59%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLL 745
            R+VANVRER R  S+N AFA LR  +PT P + +LSKI TL+LA  YI  L
Sbjct:   97 RFVANVRERQRTQSLNEAFASLRQIIPTLPSD-KLSKIQTLKLATRYIDFL 146
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Sea Lamprey
Match: TWIST1 (twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428])

HSP 1 Score: 59.6918 bits (143), Expect = 6.567e-11
Identity = 30/51 (58.82%), Postives = 36/51 (70.59%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLL 745
            R+VANVRER R  S+N AFA LR  +PT P + +LSKI TL+LA  YI  L
Sbjct:  115 RFVANVRERQRTQSLNEAFASLRQIIPTLPSD-KLSKIQTLKLATRYIDFL 164
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Nematostella
Match: EDO43849 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXI0])

HSP 1 Score: 77.411 bits (189), Expect = 2.246e-18
Identity = 33/55 (60.00%), Postives = 42/55 (76.36%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R+ AN+RER R+ SIN AF  LR  +PT PYE+RLSK+DTLRLAI YI  L +++
Sbjct:    4 RHAANLRERKRMQSINEAFEGLRKHIPTLPYEKRLSKVDTLRLAIGYIGFLTEMI 58
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Nematostella
Match: EDO42924 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZZ0])

HSP 1 Score: 61.2326 bits (147), Expect = 2.052e-12
Identity = 30/55 (54.55%), Postives = 39/55 (70.91%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  AN RERNR  S+N AF  LR  +PT P +R+LSKI+TLRLA +YI+ L  ++
Sbjct:    3 RQAANARERNRTHSVNAAFNALRLLIPTEPSDRKLSKIETLRLASSYIAHLSTIL 57
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Nematostella
Match: EDO36266 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ30])

HSP 1 Score: 60.077 bits (144), Expect = 9.721e-12
Identity = 27/54 (50.00%), Postives = 39/54 (72.22%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDL 754
            R +AN RER+RI +++ AF  LR  VP++  +++LSK+  LRLA +YIS L DL
Sbjct:    4 RLIANARERSRIHTMSEAFESLRKAVPSYSQDQKLSKLAILRLATSYISALADL 57
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Nematostella
Match: EDO42907 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S063])

HSP 1 Score: 55.4546 bits (132), Expect = 2.108e-10
Identity = 28/58 (48.28%), Postives = 36/58 (62.07%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYF 766
            R  AN RERNR+  +N AF  LR+++P    E++ SKIDT+RLA  YI   QDL    
Sbjct:    5 RRTANERERNRVQQVNAAFETLRNKIPLRALEKKPSKIDTIRLATRYI---QDLTQLL 59
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Nematostella
Match: TWIST (Predicted protein; Twist family bHLH transcription factor [Source:UniProtKB/TrEMBL;Acc:Q6S5G7])

HSP 1 Score: 56.9954 bits (136), Expect = 2.969e-10
Identity = 32/83 (38.55%), Postives = 48/83 (57.83%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILN 841
            R +ANVRER R  ++N AF +LR  +PT P + +LSKI TLRLA  YI  L  ++   + H      P+ ++  +F+    L+
Sbjct:   38 RAIANVRERQRTQALNEAFNKLRKIIPTLPSD-KLSKIQTLRLASRYIDFLCQVLGNNEKH------PSSALSSSFIAHERLS 113
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Medaka
Match: si:dkey-34f9.3 (si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-410])

HSP 1 Score: 89.7373 bits (221), Expect = 7.021e-21
Identity = 39/55 (70.91%), Postives = 50/55 (90.91%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R+ AN+RER R++SIN+AF ELR  VPTFPYE+RLSKIDTLRLAIAYI+LL++++
Sbjct:  126 RHAANIRERKRMLSINSAFEELRCHVPTFPYEKRLSKIDTLRLAIAYIALLREIL 180
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Medaka
Match: ferd3l (Fer3 like bHLH transcription factor [Source:NCBI gene;Acc:101167882])

HSP 1 Score: 76.2554 bits (186), Expect = 2.261e-17
Identity = 36/55 (65.45%), Postives = 44/55 (80.00%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  ANVRER R+ S+N AF ELR +VPTF YE+RLS+I+TLRLAI YIS + DL+
Sbjct:   16 RQAANVRERRRMFSLNEAFDELRRKVPTFAYEKRLSRIETLRLAIVYISFMTDLL 70
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Medaka
Match: ptf1a (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:101160350])

HSP 1 Score: 80.8777 bits (198), Expect = 4.004e-17
Identity = 37/55 (67.27%), Postives = 43/55 (78.18%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  ANVRER R+ SIN AF  LRS +PT PYE+RLSK+DTLRLAI YI+ L +LV
Sbjct:  120 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELV 174
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Medaka
Match: tcf15 (transcription factor 15 [Source:NCBI gene;Acc:101172734])

HSP 1 Score: 67.781 bits (164), Expect = 3.193e-13
Identity = 32/62 (51.61%), Postives = 42/62 (67.74%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHA 778
            R  AN RER R  S+NTAF  LR+ +PT P +R+LSKI+TLRLA +YIS L +++      A
Sbjct:   64 RSAANARERGRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYISHLANVLLTGDGCA 125
[Close]
BLAST of BHLH domain-containing protein vs. Ensembl Medaka
Match: scxb (scleraxis bHLH transcription factor [Source:NCBI gene;Acc:101167982])

HSP 1 Score: 68.1662 bits (165), Expect = 5.102e-13
Identity = 33/67 (49.25%), Postives = 46/67 (68.66%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQN-HAYENC 790
            R  AN RER+R  S+NTAF  LR+ +PT P +R+LSKI+TLRLA +YIS L +++   +  H  + C
Sbjct:   98 RTAANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLLGEGLHDGQPC 164
[Close]
BLAST of BHLH domain-containing protein vs. Planmine SMEST
Match: SMESG000045286.1 (SMESG000045286.1)

HSP 1 Score: 345.125 bits (884), Expect = 1.414e-118
Identity = 163/164 (99.39%), Postives = 164/164 (100.00%), Query Frame = 2 
Query:  440 MNEEIYNYKNIDMYGQYKSMININSTSENTWNISDYTFTYQNPSTMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTWFTSDLITRLSWINWDKLGCQEP 931
            MNEEIYNYKNIDMYGQYKSMININSTSENTWNISDYTFTYQNPSTMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLM+HILNDNRNQVTWFTSDLITRLSWINWDKLGCQEP
Sbjct:    1 MNEEIYNYKNIDMYGQYKSMININSTSENTWNISDYTFTYQNPSTMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMEHILNDNRNQVTWFTSDLITRLSWINWDKLGCQEP 164
[Close]
BLAST of BHLH domain-containing protein vs. Planmine SMEST
Match: SMESG000000956.1 (SMESG000000956.1)

HSP 1 Score: 82.8037 bits (203), Expect = 5.095e-18
Identity = 49/128 (38.28%), Postives = 72/128 (56.25%), Query Frame = 2 
Query:  407 NICMEINSTFRMNEEIYNYKNIDMYGQYKSMININSTSENTWNISD---YTFTYQNPSTMFDE--------APRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            N  +E +  FR+   +    N     Q   +   +++S +T N SD   Y F  ++  +++ +        A R  AN+RER R+ SIN AF  LR  +PT PYE+RLSK+DTLRLAI+YI  LQ+L+
Sbjct:   31 NTSIETDGAFRIPVTLEMSNNYYHNDQPSFVTQFSASSPSTINGSDLKSYRFNTKSHRSLYRKNRNYQRKLAERQAANIRERRRMQSINEAFEGLRCHIPTMPYEKRLSKVDTLRLAISYIGFLQELI 158
[Close]
BLAST of BHLH domain-containing protein vs. Planmine SMEST
Match: SMESG000079648.1 (SMESG000079648.1)

HSP 1 Score: 82.0333 bits (201), Expect = 6.430e-18
Identity = 37/55 (67.27%), Postives = 44/55 (80.00%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  AN+RER R+ SIN AF  LR+ +PT PYE+RLSK+DTLRLAI YI+ LQDLV
Sbjct:  104 RQAANLRERRRMQSINEAFEGLRAHIPTLPYEKRLSKVDTLRLAIGYINFLQDLV 158
[Close]
BLAST of BHLH domain-containing protein vs. Planmine SMEST
Match: SMESG000044960.1 (SMESG000044960.1)

HSP 1 Score: 74.3294 bits (181), Expect = 1.509e-15
Identity = 32/55 (58.18%), Postives = 42/55 (76.36%), Query Frame = 2 
Query:  593 RYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            R  AN+RER R+ SIN AF +LR  +PT PYE+RLSK+DTLR+AI YI+ L  ++
Sbjct:   48 RQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIM 102
[Close]
BLAST of BHLH domain-containing protein vs. Planmine SMEST
Match: SMESG000029000.1 (SMESG000029000.1)

HSP 1 Score: 72.4034 bits (176), Expect = 1.219e-14
Identity = 34/57 (59.65%), Postives = 43/57 (75.44%), Query Frame = 2 
Query:  587 APRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLV 757
            A R  AN+RER R+ S+N AF  LR RVPTF YE+RLS+I+TLRLAI YI  + +L+
Sbjct:  137 AQRRAANIRERRRMYSLNEAFDSLRKRVPTFAYEKRLSRIETLRLAITYICFMTELL 193
The following BLAST results are available for this feature:
BLAST of BHLH domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PTF1A1.456e-1667.27pancreas associated transcription factor 1a [Sourc... [more]
FERD3L2.502e-1550.68Fer3 like bHLH transcription factor [Source:HGNC S... [more]
SCX9.332e-1351.52scleraxis bHLH transcription factor [Source:HGNC S... [more]
HAND21.321e-1156.36heart and neural crest derivatives expressed 2 [So... [more]
HAND21.337e-1143.21heart and neural crest derivatives expressed 2 [So... [more]
back to top
BLAST of BHLH domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hlh-137.185e-2446.15Helix-loop-helix protein 13 [Source:UniProtKB/Swi... [more]
hlh-157.287e-1239.08Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q18... [more]
lin-321.514e-737.31pep chromosome:WBcel235:X:2229208:2230122:-1 gene:... [more]
hlh-84.135e-746.30Twist-related protein [Source:UniProtKB/Swiss-Pro... [more]
hlh-64.302e-744.44Helix-loop-helix protein 6 [Source:UniProtKB/Swis... [more]
back to top
BLAST of BHLH domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Fer23.731e-2555.45gene:FBgn0038402 transcript:FBtr0301709[more]
Fer22.084e-2453.04gene:FBgn0038402 transcript:FBtr0344010[more]
Fer27.405e-2451.26gene:FBgn0038402 transcript:FBtr0344011[more]
Fer24.499e-2253.64gene:FBgn0038402 transcript:FBtr0344012[more]
Fer13.332e-1742.45gene:FBgn0037475 transcript:FBtr0081567[more]
back to top
BLAST of BHLH domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-34f9.31.989e-2952.78si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-41... [more]
ptf1a7.070e-1767.27pancreas associated transcription factor 1a [Sourc... [more]
ferd3l7.783e-1660.00Fer3-like bHLH transcription factor [Source:ZFIN;A... [more]
si:ch211-246m6.41.136e-1345.95si:ch211-246m6.4 [Source:ZFIN;Acc:ZDB-GENE-050208-... [more]
tcf153.820e-1340.43transcription factor 15 [Source:ZFIN;Acc:ZDB-GENE-... [more]
back to top
BLAST of BHLH domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000031930.18.225e-2263.89pep primary_assembly:Xenopus_tropicalis_v9.1:9:556... [more]
PTF1A2.168e-1667.27pancreas associated transcription factor 1a [Sourc... [more]
ferd3l2.351e-1456.14Fer3-like bHLH transcription factor [Source:NCBI g... [more]
adra1d4.189e-1351.67adrenoceptor alpha 1D [Source:Xenbase;Acc:XB-GENE-... [more]
tcf155.517e-1351.67transcription factor 15 [Source:NCBI gene;Acc:5492... [more]
back to top
BLAST of BHLH domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ptf1a9.702e-1767.27pancreas specific transcription factor, 1a [Source... [more]
Ferd3l1.195e-1457.89Fer3 like bHLH transcription factor [Source:MGI Sy... [more]
Scx8.275e-1352.54scleraxis [Source:MGI Symbol;Acc:MGI:102934][more]
Tcf154.439e-1247.06transcription factor 15 [Source:MGI Symbol;Acc:MGI... [more]
Hand29.069e-1256.36heart and neural crest derivatives expressed 2 [So... [more]
back to top
BLAST of BHLH domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q20561|HLH13_CAEEL9.140e-2346.15Helix-loop-helix protein 13 OS=Caenorhabditis eleg... [more]
sp|Q7ZSX3|PTF1A_DANRE5.337e-1667.27Pancreas transcription factor 1 subunit alpha OS=D... [more]
sp|Q64305|PTF1A_RAT6.052e-1667.27Pancreas transcription factor 1 subunit alpha OS=R... [more]
sp|Q9QX98|PTF1A_MOUSE6.786e-1667.27Pancreas transcription factor 1 subunit alpha OS=M... [more]
sp|Q7RTS3|PTF1A_HUMAN6.993e-1667.27Pancreas transcription factor 1 subunit alpha OS=H... [more]
back to top
BLAST of BHLH domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
U5YQC91.529e-53100.00Ptf-3 protein (Fragment) OS=Schmidtea mediterranea... [more]
A0A4Z2CRU73.144e-2941.33Helix-loop-helix protein OS=Schistosoma japonicum ... [more]
A0A2C9M5781.000e-2844.59BHLH domain-containing protein OS=Biomphalaria gla... [more]
A0A430QCS16.556e-2846.83BHLH domain-containing protein OS=Schistosoma bovi... [more]
A0A5K4FAF37.126e-2838.89Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
back to top
BLAST of BHLH domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-34f9.33.181e-2851.85neurogenic differentiation factor 1-like [Source:N... [more]
ferd3l6.824e-1762.96Fer3-like bHLH transcription factor [Source:ZFIN;A... [more]
ptf1a9.353e-1767.27pancreas associated transcription factor 1a [Sourc... [more]
scxa1.226e-1348.57scleraxis bHLH transcription factor a [Source:ZFIN... [more]
tcf153.475e-1350.00transcription factor 15 [Source:NCBI gene;Acc:1030... [more]
back to top
BLAST of BHLH domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-34f9.31.003e-2751.85si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-41... [more]
ENSPMAT00000004072.11.270e-1765.45pep scaffold:Pmarinus_7.0:GL492732:1750:4325:-1 ge... [more]
scxa3.933e-1152.94scleraxis bHLH transcription factor a [Source:ZFIN... [more]
TWIST14.335e-1158.82twist family bHLH transcription factor 1 [Source:H... [more]
TWIST16.567e-1158.82twist family bHLH transcription factor 1 [Source:H... [more]
back to top
BLAST of BHLH domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of BHLH domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO438492.246e-1860.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO429242.052e-1254.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO362669.721e-1250.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO429072.108e-1048.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
TWIST2.969e-1038.55Predicted protein; Twist family bHLH transcription... [more]
back to top
BLAST of BHLH domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-34f9.37.021e-2170.91si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-41... [more]
ferd3l2.261e-1765.45Fer3 like bHLH transcription factor [Source:NCBI g... [more]
ptf1a4.004e-1767.27pancreas associated transcription factor 1a [Sourc... [more]
tcf153.193e-1351.61transcription factor 15 [Source:NCBI gene;Acc:1011... [more]
scxb5.102e-1349.25scleraxis bHLH transcription factor [Source:NCBI g... [more]
back to top
BLAST of BHLH domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000045286.11.414e-11899.39SMESG000045286.1[more]
SMESG000000956.15.095e-1838.28SMESG000000956.1[more]
SMESG000079648.16.430e-1867.27SMESG000079648.1[more]
SMESG000044960.11.509e-1558.18SMESG000044960.1[more]
SMESG000029000.11.219e-1459.65SMESG000029000.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005025 ID=SMED30005025|Name=BHLH domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1021bp
ATATATGGTAAAAAGTGTGTTTGAATGGCGCTATCTCATAATTATAATTA
TTATTATTATTTGTTGGAAAATAAATAAATTGAATTGAAATAATAAAATG
TTTTTTATTAACAACGGATTCAGCGAATAATTTAAATTATTACTGATTGA
GGAAATTTATGAAAAATCTTGAAATAATATTTATCTGGTTATGTAGTGGA
TGTAAATTAACGCGGACATATTTCAATTGAACATGATAACTCTTGAAATT
CTTTAAGAGAAATGCCATATCAGCGATGCGTAGAGGCGATGAGTTCGAGT
CACGGCTGAAGAGCTACCAAATTGCCAACAGCTAGTTGAGGAGTCTATAA
CGAAATTGCTTGATAAATTCATATTAATGTGAGAATATAAATAGGCAAAC
AAATTTAACATTTGTATGGAAATAAACTCGACATTCCGAATGAATGAGGA
GATATACAATTATAAAAACATCGACATGTATGGACAATACAAATCTATGA
TCAACATTAATAGCACGTCAGAAAATACTTGGAATATTTCAGATTATACG
TTTACTTATCAAAATCCTTCTACGATGTTTGACGAAGCTCCACGGTATGT
TGCCAACGTACGGGAACGGAATCGTATAATGAGCATCAATACAGCTTTTG
CGGAGTTGCGTTCACGAGTCCCAACATTTCCGTATGAAAGGAGATTATCG
AAAATTGACACTCTCAGATTAGCCATAGCCTACATCAGTTTATTGCAGGA
TCTCGTTTGGTATTTTCAAAACCATGCCTACGAAAACTGTGAACCCAACG
ACAGCATTATCAAGAATTTTCTTATGGACCACATTCTTAATGACAATAGA
AATCAAGTGACTTGGTTTACAAGCGACCTAATTACAAGACTAAGCTGGAT
TAATTGGGATAAATTGGGTTGTCAAGAGCCGTTAGAATTTTCTCACACTT
TACCGTTTACAAATAAATAGAATGCCTAATTTAGTGTTTTCTTGTTTAGC
TGAATAGTTTTAGGCAGATCG
back to top

protein sequence of SMED30005025-orf-1

>SMED30005025-orf-1 ID=SMED30005025-orf-1|Name=SMED30005025-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=185bp
MEINSTFRMNEEIYNYKNIDMYGQYKSMININSTSENTWNISDYTFTYQN
PSTMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTL
RLAIAYISLLQDLVWYFQNHAYENCEPNDSIIKNFLMDHILNDNRNQVTW
FTSDLITRLSWINWDKLGCQEPLEFSHTLPFTNK*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000120progenitor cell
PLANA:0000121stem cell
PLANA:0000418head
PLANA:0002142parenchyma
Vocabulary: INTERPRO
TermDefinition
IPR036638HLH_DNA-bd_sf
IPR011598bHLH_dom
Vocabulary: molecular function
TermDefinition
GO:0046983protein dimerization activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainSMARTSM00353finuluscoord: 64..116
e-value: 9.3E-14
score: 61.7
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainPFAMPF00010HLHcoord: 63..111
e-value: 2.4E-16
score: 59.4
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainPROSITEPS50888BHLHcoord: 58..110
score: 14.754
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainCDDcd00083HLHcoord: 63..114
e-value: 3.03242E-16
score: 67.2391
IPR036638Helix-loop-helix DNA-binding domain superfamilyGENE3DG3DSA:4.10.280.10coord: 59..115
e-value: 3.6E-23
score: 83.1
IPR036638Helix-loop-helix DNA-binding domain superfamilySUPERFAMILYSSF47459HLH, helix-loop-helix DNA-binding domaincoord: 57..119
NoneNo IPR availablePANTHERPTHR23349:SF9748 RELATED 2, ISOFORM Dcoord: 56..170
NoneNo IPR availablePANTHERPTHR23349BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWISTcoord: 56..170