Anoctamin

Overview
NameAnoctamin
Smed IDSMED30004957
Length (bp)2902
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Anoctamin (SMED30004957) t-SNE clustered cells

Violin plots show distribution of expression levels for Anoctamin (SMED30004957) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Anoctamin (SMED30004957) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Anoctamin (SMED30004957) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30004957

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 18

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30004957h1SMcG0006651 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30004957h1SMcG0006651 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30004957h1SMcG0006651 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30004957h1SMcG0006651 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30004957h1SMcG0006651 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30004957h1SMcG0006651 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30004957h1SMcG0006651 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30004957h1SMcG0006651 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30004957h1SMcG0006651 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30004957h1SMcG0006650 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30004957h1SMcG0006650 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30004957h1SMcG0006650 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30004957h1SMcG0006650 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30004957h1SMcG0006650 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30004957h1SMcG0006650 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30004957h1SMcG0006650 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30004957h1SMcG0006650 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30004957h1SMcG0006650 dd_Smed_v4_6514_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Anoctamin vs. Ensembl Human
Match: ANO6 (anoctamin 6 [Source:HGNC Symbol;Acc:HGNC:25240])

HSP 1 Score: 339.347 bits (869), Expect = 1.923e-101
Identity = 292/935 (31.23%), Postives = 456/935 (48.77%), Query Frame = 3 
Query:  195 RIPKTTTNNG----LFFTDGIRQIDFVLAYQ--------KLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFG---NSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDK--GNESSVPF--WRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL-------MMHPSPLVTQMX-XXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKA--MSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYS--PTGD-----LKGFSDFTLSYLKSSEFASST---------NETYCRYMDFRH---HPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            R P+    NG    LFF DG R+IDFVL Y+        K   NE+ R+ R  +   L+  GL+ E      +             +K+VF+K+ A WE LC YAE++ I+ P+   P+++K   S      F   + F        +        FT PF  ++   F I  +R  FF    RS IV +IL  +  Q                                IN+ S+                 I+ L+ +        LH+    +  E   C +E ++              LY+ W   R+I + QPLD IR Y+GEKI  YF+WLG+YT  L   +++G+   ++  L+  +     E+     GG I MCP  C+ + C FWKL+        + I D+   ++ A  M +W +LFLE WKR Q  L + W+  +LQ Q E  +PE+ A  T    ++    E  +PF  W + +       S V F ++L +A ++GII+Y + ++ +        +    P+   ++     S+T SIIS I+I++L  +Y K+A  +T  E   TQ++Y++S+TMK++L +F+N YS  FY  F        PG     +   +   C  GGCL  L+ QL  IM G+ + ++  E   P + + I ++     ++V   S+ IT       R   D  L  +    +FYEYLEM+IQFGF+T+F+ +FPLAPLLAL NN+LEIR DA K  T ++R V ++ +DIG W  I+  +A LAV +NA++IAFT+  I RL+Y   +S  P GD     ++G+ + TLS  K ++F + +         N T CRY DFR+   HP + K+        YW ++AAK+ F+ + E+V+Y++   IS  IP+ ++R   +I +E  +++KLL
Sbjct:   28 RTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLD-------------DKLVFVKVHAPWEVLCTYAEIMHIKLPL--KPNDLKNRSSA-----FGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYI-VDRDAFFNPATRSRIVYFILSRVKYQ-------------------------------VINNVSKFG---------------INRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYL--------------LYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCP-QCD-RLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ-QEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCA-SAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRF-----HRVS-GSEKITP------RWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKH-----NIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLL 860
[Close]
BLAST of Anoctamin vs. Ensembl Human
Match: ANO6 (anoctamin 6 [Source:HGNC Symbol;Acc:HGNC:25240])

HSP 1 Score: 339.732 bits (870), Expect = 2.525e-101
Identity = 292/935 (31.23%), Postives = 456/935 (48.77%), Query Frame = 3 
Query:  195 RIPKTTTNNG----LFFTDGIRQIDFVLAYQ--------KLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFG---NSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDK--GNESSVPF--WRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL-------MMHPSPLVTQMX-XXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKA--MSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYS--PTGD-----LKGFSDFTLSYLKSSEFASST---------NETYCRYMDFRH---HPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            R P+    NG    LFF DG R+IDFVL Y+        K   NE+ R+ R  +   L+  GL+ E      +             +K+VF+K+ A WE LC YAE++ I+ P+   P+++K   S      F   + F        +        FT PF  ++   F I  +R  FF    RS IV +IL  +  Q                                IN+ S+                 I+ L+ +        LH+    +  E   C +E ++              LY+ W   R+I + QPLD IR Y+GEKI  YF+WLG+YT  L   +++G+   ++  L+  +     E+     GG I MCP  C+ + C FWKL+        + I D+   ++ A  M +W +LFLE WKR Q  L + W+  +LQ Q E  +PE+ A  T    ++    E  +PF  W + +       S V F ++L +A ++GII+Y + ++ +        +    P+   ++     S+T SIIS I+I++L  +Y K+A  +T  E   TQ++Y++S+TMK++L +F+N YS  FY  F        PG     +   +   C  GGCL  L+ QL  IM G+ + ++  E   P + + I ++     ++V   S+ IT       R   D  L  +    +FYEYLEM+IQFGF+T+F+ +FPLAPLLAL NN+LEIR DA K  T ++R V ++ +DIG W  I+  +A LAV +NA++IAFT+  I RL+Y   +S  P GD     ++G+ + TLS  K ++F + +         N T CRY DFR+   HP + K+        YW ++AAK+ F+ + E+V+Y++   IS  IP+ ++R   +I +E  +++KLL
Sbjct:   46 RTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLD-------------DKLVFVKVHAPWEVLCTYAEIMHIKLPL--KPNDLKNRSSA-----FGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYI-VDRDAFFNPATRSRIVYFILSRVKYQ-------------------------------VINNVSKFG---------------INRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYL--------------LYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCP-QCD-RLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ-QEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCA-SAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRF-----HRVS-GSEKITP------RWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKH-----NIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLL 878
[Close]
BLAST of Anoctamin vs. Ensembl Human
Match: ANO6 (anoctamin 6 [Source:HGNC Symbol;Acc:HGNC:25240])

HSP 1 Score: 339.732 bits (870), Expect = 4.024e-101
Identity = 292/935 (31.23%), Postives = 456/935 (48.77%), Query Frame = 3 
Query:  195 RIPKTTTNNG----LFFTDGIRQIDFVLAYQ--------KLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFG---NSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDK--GNESSVPF--WRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL-------MMHPSPLVTQMX-XXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKA--MSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYS--PTGD-----LKGFSDFTLSYLKSSEFASST---------NETYCRYMDFRH---HPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            R P+    NG    LFF DG R+IDFVL Y+        K   NE+ R+ R  +   L+  GL+ E      +             +K+VF+K+ A WE LC YAE++ I+ P+   P+++K   S      F   + F        +        FT PF  ++   F I  +R  FF    RS IV +IL  +  Q                                IN+ S+                 I+ L+ +        LH+    +  E   C +E ++              LY+ W   R+I + QPLD IR Y+GEKI  YF+WLG+YT  L   +++G+   ++  L+  +     E+     GG I MCP  C+ + C FWKL+        + I D+   ++ A  M +W +LFLE WKR Q  L + W+  +LQ Q E  +PE+ A  T    ++    E  +PF  W + +       S V F ++L +A ++GII+Y + ++ +        +    P+   ++     S+T SIIS I+I++L  +Y K+A  +T  E   TQ++Y++S+TMK++L +F+N YS  FY  F        PG     +   +   C  GGCL  L+ QL  IM G+ + ++  E   P + + I ++     ++V   S+ IT       R   D  L  +    +FYEYLEM+IQFGF+T+F+ +FPLAPLLAL NN+LEIR DA K  T ++R V ++ +DIG W  I+  +A LAV +NA++IAFT+  I RL+Y   +S  P GD     ++G+ + TLS  K ++F + +         N T CRY DFR+   HP + K+        YW ++AAK+ F+ + E+V+Y++   IS  IP+ ++R   +I +E  +++KLL
Sbjct:   67 RTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLD-------------DKLVFVKVHAPWEVLCTYAEIMHIKLPL--KPNDLKNRSSA-----FGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYI-VDRDAFFNPATRSRIVYFILSRVKYQ-------------------------------VINNVSKFG---------------INRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYL--------------LYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCP-QCD-RLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ-QEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCA-SAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRF-----HRVS-GSEKITP------RWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKH-----NIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLL 899
[Close]
BLAST of Anoctamin vs. Ensembl Human
Match: ANO4 (anoctamin 4 [Source:HGNC Symbol;Acc:HGNC:23837])

HSP 1 Score: 325.479 bits (833), Expect = 4.481e-96
Identity = 273/924 (29.55%), Postives = 451/924 (48.81%), Query Frame = 3 
Query:  189 NERIPKTTTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNI--KYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHE-SFIVQNSLKRD--ESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSD--VYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFF---------KFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--------LKGFSDFTLSYLKSSEFA------------SSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
             E +P+   +NGL+F DG  +ID++L Y+K N     R++   F + +  +GL+ E +       SL N D       I+F+K                     LH P  +  +Y + ++ R                         MPF     YL      R+Y F+      I  +  R +  +  R     L ++       +  ++  +  F   N E+       NN      +  I   I+  +    + L+ L++   +E+A+ LHE S+  +NS++    E+ R  LY+CW       + QPLD +R YFGEKI  YF+WLG+YT  LF  + +GL + ++ +       +  E+ +  +I MCP +C+ K C F +LSD  VY K  V  + DN   +  A  M++WA++FLE WKR +  +A+ W++ D + + E  +P+F A  ++       E   P   +  P+  F           S + F + + +A + GI++Y +V  +        L+   S V  + T   I+  +I+LL ++Y K+A  LT LE   T+SE+++S T+K++L +F+N  S  FY  F L      PG   + ++  +   C   GCL  L +Q+  IM+ +Q  ++F E  YPL+ +   + K+R+ +  +   + I+    E      D  L  + +  +F EYLEM++QFGF T+F+ AFPLAPLLAL NN++EIR DA KF+T ++RP+A R KDIG W  IL  +  L+V +NA +IA T+ FI RL+Y  KY P           + G+ + +LS  + S+F             S T   YCRY D+R  P  +   P   T  +W +LAA++ F+ +FE++V+ I  +IS  IP+  + +   + +E  + ++++
Sbjct:   63 GETVPERNKSNGLYFRDGKCRIDYILVYRKSNPQTEKREV---FERNIRAEGLQMEKES------SLINSD-------IIFVK---------------------LHAPWEVLGRYAEQMNVR-------------------------MPFRRKIYYL-----PRRYKFMSRIDKQISRF-RRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKET-----FFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDIIMCP-VCD-KYCPFMRLSDSCVYAK--VTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSK------KERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPE---RKISFPQWE-----KDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLV--PYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 893
[Close]
BLAST of Anoctamin vs. Ensembl Human
Match: ANO4 (anoctamin 4 [Source:HGNC Symbol;Acc:HGNC:23837])

HSP 1 Score: 324.324 bits (830), Expect = 2.176e-95
Identity = 273/924 (29.55%), Postives = 451/924 (48.81%), Query Frame = 3 
Query:  189 NERIPKTTTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNI--KYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHE-SFIVQNSLKRD--ESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSD--VYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFF---------KFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--------LKGFSDFTLSYLKSSEFA------------SSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
             E +P+   +NGL+F DG  +ID++L Y+K N     R++   F + +  +GL+ E +       SL N D       I+F+K                     LH P  +  +Y + ++ R                         MPF     YL      R+Y F+      I  +  R +  +  R     L ++       +  ++  +  F   N E+       NN      +  I   I+  +    + L+ L++   +E+A+ LHE S+  +NS++    E+ R  LY+CW       + QPLD +R YFGEKI  YF+WLG+YT  LF  + +GL + ++ +       +  E+ +  +I MCP +C+ K C F +LSD  VY K  V  + DN   +  A  M++WA++FLE WKR +  +A+ W++ D + + E  +P+F A  ++       E   P   +  P+  F           S + F + + +A + GI++Y +V  +        L+   S V  + T   I+  +I+LL ++Y K+A  LT LE   T+SE+++S T+K++L +F+N  S  FY  F L      PG   + ++  +   C   GCL  L +Q+  IM+ +Q  ++F E  YPL+ +   + K+R+ +  +   + I+    E      D  L  + +  +F EYLEM++QFGF T+F+ AFPLAPLLAL NN++EIR DA KF+T ++RP+A R KDIG W  IL  +  L+V +NA +IA T+ FI RL+Y  KY P           + G+ + +LS  + S+F             S T   YCRY D+R  P  +   P   T  +W +LAA++ F+ +FE++V+ I  +IS  IP+  + +   + +E  + ++++
Sbjct:   98 GETVPERNKSNGLYFRDGKCRIDYILVYRKSNPQTEKREV---FERNIRAEGLQMEKES------SLINSD-------IIFVK---------------------LHAPWEVLGRYAEQMNVR-------------------------MPFRRKIYYL-----PRRYKFMSRIDKQISRF-RRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKET-----FFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDIIMCP-VCD-KYCPFMRLSDSCVYAK--VTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSK------KERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPE---RKISFPQWE-----KDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLV--PYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 928
[Close]
BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-1 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286])

HSP 1 Score: 137.887 bits (346), Expect = 6.061e-33
Identity = 154/590 (26.10%), Postives = 255/590 (43.22%), Query Frame = 3 
Query:  867 SHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCW----------GLTRNICRS---QPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDI--------IVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNE-----SSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIIL---------YEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILP---LIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCS--SIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLL 2516
              S ++ TD   + I     ++++L    L  L+   V+E A+ LH     +   K  ++  VK Y  +           L+ N  R    QPL+ IR YFGE+IA+YF+W G +   L+   + GLV+ ++  + + S          +VN I +  N+      C  +       S V   F  +   D K     A  MSIW S+F+++WKR    L++ WN  D  +  EP +PEF     +     G +     +   + +    F+F  FS ++  + L L  L+ I +         Y    +      PS L T                +  + L  +Y+ L   L   EN+ T+SE+++S+ +K++  + +N Y+ LFY  FI P    +QP   F   ++ K   C    C   L++QL    + +     F +   P       ++ Y  R   +V+    +  NV   ++R +      D     V +E  E +I FG   MF   FPLAPLLAL    +++R DA + +   ++P+      IG W+ IL+ +   AV +NA ++AFT+ F    L
Sbjct:  181 GESQDEPTDPSTSSI----TSDEQLRRKGLSWLLMSDVYEEAFVLHAPSKEEPYFKAMQNGSVKAYNEFISEIELDPRRSLSLNWERWYKFQPLNKIRDYFGEQIAYYFAWQGTFLTLLWPAVIFGLVVFIYGFIDSISSAPLDWNHCKVVNFIGQTENVA-----CGMRNGVTLFFSMVTQWF--MSSFDTKMNAFFAVFMSIWGSVFVQIWKRNNSVLSYQWNSDDF-HAIEPDRPEFRGSKVKEDPITGEDIWISPALARYIKMLASFVFVSFSMLVVVISLMLVTLLKIWMVYNFQCTKEYTFHCWLSAAFLPSILNT----------------LSAMGLGAIYSNLVSRLNSWENHRTESEHNNSLIVKIFAFQMVNTYTSLFYVAFIRPESHGLQPNGLFGLGTEFKDT-CLDDTCSSLLALQLLTHTLIKPFPKFFKDVVLPYFVKLFRLRMYTSRTEARVEIEDDDQANV---LVREWLKPSAGDF----VLWEMNEKIILFGTTMMFASLFPLAPLLALIIGFVDMRIDAHRLIWFNRKPIPIITNGIGIWLPILTFLQYCAVFTNAFIVAFTSGFCSTFL 734
[Close]
BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-1 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286])

HSP 1 Score: 137.502 bits (345), Expect = 7.413e-33
Identity = 154/590 (26.10%), Postives = 255/590 (43.22%), Query Frame = 3 
Query:  867 SHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCW----------GLTRNICRS---QPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDI--------IVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNE-----SSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIIL---------YEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILP---LIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCS--SIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLL 2516
              S ++ TD   + I     ++++L    L  L+   V+E A+ LH     +   K  ++  VK Y  +           L+ N  R    QPL+ IR YFGE+IA+YF+W G +   L+   + GLV+ ++  + + S          +VN I +  N+      C  +       S V   F  +   D K     A  MSIW S+F+++WKR    L++ WN  D  +  EP +PEF     +     G +     +   + +    F+F  FS ++  + L L  L+ I +         Y    +      PS L T                +  + L  +Y+ L   L   EN+ T+SE+++S+ +K++  + +N Y+ LFY  FI P    +QP   F   ++ K   C    C   L++QL    + +     F +   P       ++ Y  R   +V+    +  NV   ++R +      D     V +E  E +I FG   MF   FPLAPLLAL    +++R DA + +   ++P+      IG W+ IL+ +   AV +NA ++AFT+ F    L
Sbjct:  163 GESQDEPTDPSTSSI----TSDEQLRRKGLSWLLMSDVYEEAFVLHAPSKEEPYFKAMQNGSVKAYNEFISEIELDPRRSLSLNWERWYKFQPLNKIRDYFGEQIAYYFAWQGTFLTLLWPAVIFGLVVFIYGFIDSISSAPLDWNHCKVVNFIGQTENVA-----CGMRNGVTLFFSMVTQWF--MSSFDTKMNAFFAVFMSIWGSVFVQIWKRNNSVLSYQWNSDDF-HAIEPDRPEFRGSKVKEDPITGEDIWISPALARYIKMLASFVFVSFSMLVVVISLMLVTLLKIWMVYNFQCTKEYTFHCWLSAAFLPSILNT----------------LSAMGLGAIYSNLVSRLNSWENHRTESEHNNSLIVKIFAFQMVNTYTSLFYVAFIRPESHGLQPNGLFGLGTEFKDT-CLDDTCSSLLALQLLTHTLIKPFPKFFKDVVLPYFVKLFRLRMYTSRTEARVEIEDDDQANV---LVREWLKPSAGDF----VLWEMNEKIILFGTTMMFASLFPLAPLLALIIGFVDMRIDAHRLIWFNRKPIPIITNGIGIWLPILTFLQYCAVFTNAFIVAFTSGFCSTFL 716
[Close]
BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-2 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3])

HSP 1 Score: 100.523 bits (249), Expect = 2.620e-21
Identity = 94/391 (24.04%), Postives = 151/391 (38.62%), Query Frame = 3 
Query: 1101 QPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLV---IAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDL-QNQY-EPQKPEFVA-FITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIIL--------------------YEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIK----KYKLRKCNKVKYRSKNITNVN 2183
            QP+D ++ YFG +IA YF+WLG  T  L+FPSLLG++   +  F   ++  D                     KQ  +  +SD+ +             +L AF   IW++++LE WKR Q  LAF W  YD  Q+ Y +  +P F   ++  N      E   P W+ TV      +      V+   A ++ I                      + ++ YAL+++    +                           Y +LA  L  LEN  T  EY+D +  K+ L +F+  +  LFY  F+L             D+K            L   LA ++I RQ+  +  E   P +   +K     YK+ +        +++ NV 
Sbjct:  213 QPIDQVKDYFGTEIAMYFAWLGHMTTALWFPSLLGILMWFLGGFKYKNSPGD---------------------KQDLYQLISDICF-------------VLFAFFNCIWSTIYLEWWKRVQAELAFKWGTYDATQDSYLQDPRPAFQGDYLAPNPVSGRLEPFYPAWKHTVMRYVITYPITFLCVVGMFAAMLAIFTVQDLADFYFGDSWMLSWLCYFPMIFYALMIVISDKI---------------------------YRRLALILNDLENYRTDDEYEDFLITKIVLFQFVTAFGSLFYIAFVL------------RDMK-----------RLQETLATLLITRQVTQNIMETVVPFMIEKLKLSSLTYKMTRSMSDGTLRRHVENVR 519

HSP 2 Score: 56.9954 bits (136), Expect = 6.776e-8
Identity = 47/104 (45.19%), Postives = 61/104 (58.65%), Query Frame = 3 
Query: 2199 CYD---DLLLADLESQPVFY-----EYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIA 2486
            C D   +L  A+LES    Y     ++LEM IQFG++ +F PAFPLA + AL NNL+EIR DA K     +RP  +RVKDIG W   + ++  L V  N  LI 
Sbjct:  600 CTDSNPELTQAELESVMSVYARPLDDFLEMFIQFGYVLLFSPAFPLAAVCALINNLIEIRVDAFKLCNTVQRPFGRRVKDIGAWQKAMEILGILGVIVNCALIG 703
[Close]
BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-2 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3])

HSP 1 Score: 100.523 bits (249), Expect = 2.674e-21
Identity = 94/391 (24.04%), Postives = 151/391 (38.62%), Query Frame = 3 
Query: 1101 QPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLV---IAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDL-QNQY-EPQKPEFVA-FITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIIL--------------------YEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIK----KYKLRKCNKVKYRSKNITNVN 2183
            QP+D ++ YFG +IA YF+WLG  T  L+FPSLLG++   +  F   ++  D                     KQ  +  +SD+ +             +L AF   IW++++LE WKR Q  LAF W  YD  Q+ Y +  +P F   ++  N      E   P W+ TV      +      V+   A ++ I                      + ++ YAL+++    +                           Y +LA  L  LEN  T  EY+D +  K+ L +F+  +  LFY  F+L             D+K            L   LA ++I RQ+  +  E   P +   +K     YK+ +        +++ NV 
Sbjct:  269 QPIDQVKDYFGTEIAMYFAWLGHMTTALWFPSLLGILMWFLGGFKYKNSPGD---------------------KQDLYQLISDICF-------------VLFAFFNCIWSTIYLEWWKRVQAELAFKWGTYDATQDSYLQDPRPAFQGDYLAPNPVSGRLEPFYPAWKHTVMRYVITYPITFLCVVGMFAAMLAIFTVQDLADFYFGDSWMLSWLCYFPMIFYALMIVISDKI---------------------------YRRLALILNDLENYRTDDEYEDFLITKIVLFQFVTAFGSLFYIAFVL------------RDMK-----------RLQETLATLLITRQVTQNIMETVVPFMIEKLKLSSLTYKMTRSMSDGTLRRHVENVR 575

HSP 2 Score: 56.9954 bits (136), Expect = 7.051e-8
Identity = 47/104 (45.19%), Postives = 61/104 (58.65%), Query Frame = 3 
Query: 2199 CYD---DLLLADLESQPVFY-----EYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIA 2486
            C D   +L  A+LES    Y     ++LEM IQFG++ +F PAFPLA + AL NNL+EIR DA K     +RP  +RVKDIG W   + ++  L V  N  LI 
Sbjct:  656 CTDSNPELTQAELESVMSVYARPLDDFLEMFIQFGYVLLFSPAFPLAAVCALINNLIEIRVDAFKLCNTVQRPFGRRVKDIGAWQKAMEILGILGVIVNCALIG 759
[Close]
BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0334922)

HSP 1 Score: 389.037 bits (998), Expect = 1.478e-119
Identity = 289/919 (31.45%), Postives = 457/919 (49.73%), Query Frame = 3 
Query:  159 MYDNRFSTKDNERIPKTTTNNGLFFTDGIRQIDFVLAYQKLNDNE----RNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFT--MPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGN--ITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVA---FITQNQTD---KGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKS-------SEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLL 2849
            +YD+R  +   E   +   N  LFF D +R IDFVLAY ++N +E     N + R  F   L+ QGLE E   ++                +I F+K+ A  E L  YAE+L++R P+     N++  +                   N   +  H  T  +P  S          NR    + +    +  + LR+I +             I PK                 +   +C  + +      E + +       N       +  LI+E V+ +AY LH+  I +       + R  LYK W       R QPLD I+ YFG KI  YF+WLG+YTY L   S++G++  +++     + + V +I + GN  ITMCPL C+   C FW L +      V  ++DN + +  A  MS WA+LFLE+WKR    +   W++       E  +P+++A    I   + D      E +VPFWR  +P   F FS VL  + LA   L+ +++Y + + A L +  SP+ T  + V+ + + + ++L ++ +L  +Y  LA +LT LE   TQ+++DDS+T+K+YLL+F+N Y+ +FY  F        PG +  + D +   C +GGCL  L +QLA IM+G+Q  +   E   P+    +   ++   +++   + N      E  R   D  L D  ++ +F EYLEM++Q+GF+T+F+ AFPLAP  AL NN+LE+R DA K LT +KRPV+QRV+DIG W  IL  +  L+V +N  +IAFT+  I RL+Y    +  G L G+ +FTLS  K        S     +N T CRY DFR  P   +    TL+S+++ ILA ++ FV +FEN V  +M ++   IP+ +  +  +I +EV ++ ++++
Sbjct:   14 VYDDRECSCPREFYQRGEINTSLFFEDCVRSIDFVLAY-RINAHEPTELENTEKRRVFEANLISQGLEVESSQKD----------------QIWFVKIHAPLEVLRRYAEILKLRMPMKESLCNLRISER-----------------SNRLRNAAHYLTNKIPGMSV--------VNRSTKSVFSSLKHVFQFFLRNIYVD----------EEIFPKRAHRFTAIYSRDKEYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEITETG-----TMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPL-CD--WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQV-GLSRLFNNTPNPDKAKDE--RWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEK--YTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIII 867
[Close]
BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0083806)

HSP 1 Score: 358.607 bits (919), Expect = 1.504e-108
Identity = 232/649 (35.75%), Postives = 364/649 (56.09%), Query Frame = 3 
Query:  951 SLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGN--ITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVA---FITQNQTD---KGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKS-------SEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLL 2849
             +  LI+E V+ +AY LH+  I +       + R  LYK W       R QPLD I+ YFG KI  YF+WLG+YTY L   S++G++  +++     + + V +I + GN  ITMCPL C+   C FW L +      V  ++DN + +  A  MS WA+LFLE+WKR    +   W++       E  +P+++A    I   + D      E +VPFWR  +P   F FS VL  + LA   L+ +++Y + + A L +  SP+ T  + V+ + + + ++L ++ +L  +Y  LA +LT LE   TQ+++DDS+T+K+YLL+F+N Y+ +FY  F        PG +  + D +   C +GGCL  L +QLA IM+G+Q  +   E   P+    +   ++   +++   + N      E  R   D  L D  ++ +F EYLEM++Q+GF+T+F+ AFPLAP  AL NN+LE+R DA K LT +KRPV+QRV+DIG W  IL  +  L+V +N  +IAFT+  I RL+Y    +  G L G+ +FTLS  K        S     +N T CRY DFR  P   +    TL+S+++ ILA ++ FV +FEN V  +M ++   IP+ +  +  +I +EV ++ ++++
Sbjct:  208 GIERLIAEGVYSAAYPLHDGEITETG-----TMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPL-CD--WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQV-GLSRLFNNTPNPDKAKDE--RWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEK--YTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIII 843

HSP 2 Score: 85.8853 bits (211), Expect = 1.096e-16
Identity = 68/198 (34.34%), Postives = 95/198 (47.98%), Query Frame = 3 
Query:  159 MYDNRFSTKDNERIPKTTTNNGLFFTDGIRQIDFVLAYQKLNDNE----RNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPS----NIKYEQSLSFRKYFRKFDIFNLYFGNS-FHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYIL 725
            +YD+R  +   E   +   N  LFF D +R IDFVLAY ++N +E     N + R  F   L+ QGLE E   +                ++I F+K+ A  E L  YAE+L++R P+   P     N   +   S  K+  +F + N+Y     F  R H FT  +S  KEYLFDI   +  FF    RS IV +IL
Sbjct:   14 VYDDRECSCPREFYQRGEINTSLFFEDCVRSIDFVLAY-RINAHEPTELENTEKRRVFEANLISQGLEVESSQK----------------DQIWFVKIHAPLEVLRRYAEILKLRMPMKEIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAIYSRDKEYLFDI--RQDCFFTTAVRSRIVEFIL 192
[Close]
BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0334921)

HSP 1 Score: 358.607 bits (919), Expect = 1.504e-108
Identity = 232/649 (35.75%), Postives = 364/649 (56.09%), Query Frame = 3 
Query:  951 SLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGN--ITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVA---FITQNQTD---KGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKS-------SEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLL 2849
             +  LI+E V+ +AY LH+  I +       + R  LYK W       R QPLD I+ YFG KI  YF+WLG+YTY L   S++G++  +++     + + V +I + GN  ITMCPL C+   C FW L +      V  ++DN + +  A  MS WA+LFLE+WKR    +   W++       E  +P+++A    I   + D      E +VPFWR  +P   F FS VL  + LA   L+ +++Y + + A L +  SP+ T  + V+ + + + ++L ++ +L  +Y  LA +LT LE   TQ+++DDS+T+K+YLL+F+N Y+ +FY  F        PG +  + D +   C +GGCL  L +QLA IM+G+Q  +   E   P+    +   ++   +++   + N      E  R   D  L D  ++ +F EYLEM++Q+GF+T+F+ AFPLAP  AL NN+LE+R DA K LT +KRPV+QRV+DIG W  IL  +  L+V +N  +IAFT+  I RL+Y    +  G L G+ +FTLS  K        S     +N T CRY DFR  P   +    TL+S+++ ILA ++ FV +FEN V  +M ++   IP+ +  +  +I +EV ++ ++++
Sbjct:  208 GIERLIAEGVYSAAYPLHDGEITETG-----TMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPL-CD--WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQV-GLSRLFNNTPNPDKAKDE--RWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEK--YTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIII 843

HSP 2 Score: 85.8853 bits (211), Expect = 1.096e-16
Identity = 68/198 (34.34%), Postives = 95/198 (47.98%), Query Frame = 3 
Query:  159 MYDNRFSTKDNERIPKTTTNNGLFFTDGIRQIDFVLAYQKLNDNE----RNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPS----NIKYEQSLSFRKYFRKFDIFNLYFGNS-FHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYIL 725
            +YD+R  +   E   +   N  LFF D +R IDFVLAY ++N +E     N + R  F   L+ QGLE E   +                ++I F+K+ A  E L  YAE+L++R P+   P     N   +   S  K+  +F + N+Y     F  R H FT  +S  KEYLFDI   +  FF    RS IV +IL
Sbjct:   14 VYDDRECSCPREFYQRGEINTSLFFEDCVRSIDFVLAY-RINAHEPTELENTEKRRVFEANLISQGLEVESSQK----------------DQIWFVKIHAPLEVLRRYAEILKLRMPMKEIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAIYSRDKEYLFDI--RQDCFFTTAVRSRIVEFIL 192
[Close]
BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0083805)

HSP 1 Score: 358.992 bits (920), Expect = 2.315e-107
Identity = 232/649 (35.75%), Postives = 364/649 (56.09%), Query Frame = 3 
Query:  951 SLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGN--ITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVA---FITQNQTD---KGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKS-------SEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLL 2849
             +  LI+E V+ +AY LH+  I +       + R  LYK W       R QPLD I+ YFG KI  YF+WLG+YTY L   S++G++  +++     + + V +I + GN  ITMCPL C+   C FW L +      V  ++DN + +  A  MS WA+LFLE+WKR    +   W++       E  +P+++A    I   + D      E +VPFWR  +P   F FS VL  + LA   L+ +++Y + + A L +  SP+ T  + V+ + + + ++L ++ +L  +Y  LA +LT LE   TQ+++DDS+T+K+YLL+F+N Y+ +FY  F        PG +  + D +   C +GGCL  L +QLA IM+G+Q  +   E   P+    +   ++   +++   + N      E  R   D  L D  ++ +F EYLEM++Q+GF+T+F+ AFPLAP  AL NN+LE+R DA K LT +KRPV+QRV+DIG W  IL  +  L+V +N  +IAFT+  I RL+Y    +  G L G+ +FTLS  K        S     +N T CRY DFR  P   +    TL+S+++ ILA ++ FV +FEN V  +M ++   IP+ +  +  +I +EV ++ ++++
Sbjct:  357 GIERLIAEGVYSAAYPLHDGEITETG-----TMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPL-CD--WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQV-GLSRLFNNTPNPDKAKDE--RWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEK--YTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIII 992

HSP 2 Score: 85.8853 bits (211), Expect = 1.299e-16
Identity = 68/198 (34.34%), Postives = 95/198 (47.98%), Query Frame = 3 
Query:  159 MYDNRFSTKDNERIPKTTTNNGLFFTDGIRQIDFVLAYQKLNDNE----RNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPS----NIKYEQSLSFRKYFRKFDIFNLYFGNS-FHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYIL 725
            +YD+R  +   E   +   N  LFF D +R IDFVLAY ++N +E     N + R  F   L+ QGLE E   +                ++I F+K+ A  E L  YAE+L++R P+   P     N   +   S  K+  +F + N+Y     F  R H FT  +S  KEYLFDI   +  FF    RS IV +IL
Sbjct:  163 VYDDRECSCPREFYQRGEINTSLFFEDCVRSIDFVLAY-RINAHEPTELENTEKRRVFEANLISQGLEVESSQK----------------DQIWFVKIHAPLEVLRRYAEILKLRMPMKEIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAIYSRDKEYLFDI--RQDCFFTTAVRSRIVEFIL 341
[Close]
BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0302492)

HSP 1 Score: 358.607 bits (919), Expect = 4.060e-107
Identity = 232/649 (35.75%), Postives = 364/649 (56.09%), Query Frame = 3 
Query:  951 SLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGN--ITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVA---FITQNQTD---KGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKS-------SEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLL 2849
             +  LI+E V+ +AY LH+  I +       + R  LYK W       R QPLD I+ YFG KI  YF+WLG+YTY L   S++G++  +++     + + V +I + GN  ITMCPL C+   C FW L +      V  ++DN + +  A  MS WA+LFLE+WKR    +   W++       E  +P+++A    I   + D      E +VPFWR  +P   F FS VL  + LA   L+ +++Y + + A L +  SP+ T  + V+ + + + ++L ++ +L  +Y  LA +LT LE   TQ+++DDS+T+K+YLL+F+N Y+ +FY  F        PG +  + D +   C +GGCL  L +QLA IM+G+Q  +   E   P+    +   ++   +++   + N      E  R   D  L D  ++ +F EYLEM++Q+GF+T+F+ AFPLAP  AL NN+LE+R DA K LT +KRPV+QRV+DIG W  IL  +  L+V +N  +IAFT+  I RL+Y    +  G L G+ +FTLS  K        S     +N T CRY DFR  P   +    TL+S+++ ILA ++ FV +FEN V  +M ++   IP+ +  +  +I +EV ++ ++++
Sbjct:  381 GIERLIAEGVYSAAYPLHDGEITETG-----TMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPL-CD--WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQV-GLSRLFNNTPNPDKAKDE--RWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEK--YTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIII 1016

HSP 2 Score: 76.6406 bits (187), Expect = 9.559e-14
Identity = 69/222 (31.08%), Postives = 98/222 (44.14%), Query Frame = 3 
Query:  159 MYDNRFSTKDNERIPKTTTNNGLFFTDGIRQIDFVLAYQKLNDNE----RNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKY-EQSLSFR---------------------------KYFRKFDIFNLYFGNS-FHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYIL 725
            +YD+R  +   E   +   N  LFF D +R IDFVLAY ++N +E     N + R  F   L+ QGLE E   +                ++I F+K+ A  E L  YAE+L++R P+     N++  E+S   R                           K+  +F + N+Y     F  R H FT  +S  KEYLFDI   +  FF    RS IV +IL
Sbjct:  163 VYDDRECSCPREFYQRGEINTSLFFEDCVRSIDFVLAY-RINAHEPTELENTEKRRVFEANLISQGLEVESSQK----------------DQIWFVKIHAPLEVLRRYAEILKLRMPMKESLCNLRISERSNRLRNAAHYLTNKIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAIYSRDKEYLFDI--RQDCFFTTAVRSRIVEFIL 365
[Close]
BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano5b (anoctamin 5b [Source:ZFIN;Acc:ZDB-GENE-061215-108])

HSP 1 Score: 352.058 bits (902), Expect = 4.109e-106
Identity = 281/909 (30.91%), Postives = 440/909 (48.40%), Query Frame = 3 
Query:  219 NGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRD-ESDRVKLYKCWGLTRNIC--RSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEI---KEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQ--KPEFVAFITQ---NQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYAL---LMMHPSPLVTQMXXXXXXXXXXXXXXXX------XXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-----FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPT--GDLKGFSDFTLSYLKSSEFA--------------SSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKE 2822
            + +FF DG+R+IDFVL+Y    + ++  + R +F   L K GLE E +D+           +  D  K  ++K+ A WE L  YA++L+I+ P     S+I   + +        F +      N        FT PF  SK   F I  ++  FF  + R+ IV YIL                                          + C     +  E D+                   ++ L++   + SAY LH+    + +     ES+R  LY+ W   R +C  + QPL+ I+ Y+GEKI  YF+WLGFYT  LF+ +++G++  V+ +L    +I   EI   K GG I MCP LC+ K+C +WKL+      +   + DN+  +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+    T    N+  +  E  +PF  +   F     +TVLF   L +A ++G+I Y + +YA    +M   S    Q+   +I+   +            IL+L  +Y  +A W+T +E  +T  EY++ +TMK+++ +F+N YS  FY  F        PG     F   S L+   C  GGCL  L+ QL  +M G+Q++ +  E   PL+ +     K R   +  Y             R   D  L +     +FYEYLEM+IQFGFIT+F+ +FPLAPLLALFNN+LE+R DA KF T ++RP+A + ++IG W  IL+VVA ++V +NA ++AFT+  I RL+Y+  Y P    ++ G+   +LS    S+                +S+  T CRY D+R+ P  ++    T T  +W ILAAK+ F+ + E+VV+ +   ++  IP+    +   I +E
Sbjct:   55 DSVFFKDGVRRIDFVLSYVDDKEGDKKAERRREFEANLEKAGLELETEDK-----------SESDDRKTHYLKIHAPWEVLATYADVLKIKVPF--KVSDIPKAREVPLEWLSHPFRLPE----NIMRPEPDYFTAPFDKSKVDFFLI-DDKDTFFPPSTRNRIVYYIL------------------------------------------TRCPYYKEDRKEKDK-----------------TGINRLLNNGTYTSAYPLHDCRYWKKAQDMQCESERYHLYRYWA--RFLCFYKEQPLNLIKKYYGEKIGIYFAWLGFYTEMLFYAAVMGVICFVYGVLSYEDNITSKEICDPKIGGMIVMCP-LCD-KKCSYWKLNSTCLSSWQSHLFDNEGTVFFAMFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQIRPEYEQKCTGRRLNRITQEMEPYLPFPSKCARFC-LSGATVLFWTCLIVACIMGVIAYRLAVYAAFASVMKDSSTSKIQLVGSLITPQLATSVTASCINFVIILILNFLYEHVAIWITDMEIPKTHLEYENKLTMKMFMFQFVNYYSSCFYVAFFKGKFVGYPGNYSYMFGKWSTLRNEECAPGGCLIELTTQLLIVMAGKQMVGNVQEALLPLVRNWWSSRKGRSHPESTYS------------RWEQDHDLQNFSQFGLFYEYLEMVIQFGFITLFVASFPLAPLLALFNNILEVRVDAWKFTTQFRRPMAAKARNIGAWEEILNVVAIMSVVTNAFIMAFTSDMIPRLVYLYAYHPGIEANMTGYITNSLSIYNISQIPEDNLPEAGENPSWFNSSTITTCRYRDYRYPPGHLRQ--YTHTMQFWHILAAKLAFIIIMEHVVFVVKFFVAWLIPDVPSEVKARIKRE 867
[Close]
BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 328.176 bits (840), Expect = 7.720e-100
Identity = 226/645 (35.04%), Postives = 349/645 (54.11%), Query Frame = 3 
Query:  936 KLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESD---RVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNI-TMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFW--RRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKV-KYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            K   + +  L+ +  F  A+ LHE      S          R  LY  W      C+ QPLD IR YFGEKIA YF+WLGFYT WL   +L+G  + V  IL   S+    EI E G +  MCP LC +  CK W +SD+     V  + D+   +  +  MS+WA  FLE WKR+   LA HW+  D     EP +PEF A     + +       P++  +  +  M      ++  + + + FLV +I+Y  ++  ++    S ++   +  I +++ ++++L +ILL+  VY  LA  LT  E + TQ++Y+D+ T K+++ +F+N YS  FY  F        PG +  +  ++   C  GGCL  L+ QL  IM+G+QLI++  E+  P + +  +K  L    K  K +       + E+I C           + +F EYLE+++QFGFIT+F+ AFPLAPL AL NN +E+R DA KF+  Y+RPVA+R + IG W  IL  ++ ++V  NA LIAFT+ F+ RLLY  K++   DL G+ +FTL+Y   S   SS   T CRY  FR      +NG   L  +YWE+LA ++ F+  FE+VV+ ++++I   +P+  E +  +I +E  ++++ L
Sbjct:   14 KRAEVGVARLLRDGAFTGAFPLHEGPFKLPSCDTQPDQLNKRQVLYHYWASWLKWCKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAALVGTCVFVSGILTMGSNTPAKEICESGGLYLMCP-LCET--CKPWNMSDICPMAKVGYLFDHPGTVFFSVFMSLWAVTFLEYWKRKNATLAHHWDCMDFHEDEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMFETGSSVLRTQAGNIANISSTLVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLCIIMVGKQLINNIQEFVIPKIKAWRQKRALASVKKAQKTQEPERWEQDYELIPC-----------EGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWVEVRLDAHKFVCEYRRPVAERAQHIGVWFIILEALSHVSVVVNAFLIAFTSDFLPRLLYQYKFN--NDLHGYVNFTLAYSPPSYNHSS--HTVCRYKAFRD-----ENGKYKL--VYWELLAVRLGFIIAFEHVVFFVLRVIDWMVPDIPESLQLKIKRERYLAKQAL 633
[Close]
BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 330.487 bits (846), Expect = 2.655e-98
Identity = 226/645 (35.04%), Postives = 349/645 (54.11%), Query Frame = 3 
Query:  936 KLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESD---RVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNI-TMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFW--RRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKV-KYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            K   + +  L+ +  F  A+ LHE      S          R  LY  W      C+ QPLD IR YFGEKIA YF+WLGFYT WL   +L+G  + V  IL   S+    EI E G +  MCP LC +  CK W +SD+     V  + D+   +  +  MS+WA  FLE WKR+   LA HW+  D     EP +PEF A     + +       P++  +  +  M      ++  + + + FLV +I+Y  ++  ++    S ++   +  I +++ ++++L +ILL+  VY  LA  LT  E + TQ++Y+D+ T K+++ +F+N YS  FY  F        PG +  +  ++   C  GGCL  L+ QL  IM+G+QLI++  E+  P + +  +K  L    K  K +       + E+I C           + +F EYLE+++QFGFIT+F+ AFPLAPL AL NN +E+R DA KF+  Y+RPVA+R + IG W  IL  ++ ++V  NA LIAFT+ F+ RLLY  K++   DL G+ +FTL+Y   S   SS   T CRY  FR      +NG   L  +YWE+LA ++ F+  FE+VV+ ++++I   +P+  E +  +I +E  ++++ L
Sbjct:  260 KRAEVGVARLLRDGAFTGAFPLHEGPFKLPSCDTQPDQLNKRQVLYHYWASWLKWCKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAALVGTCVFVSGILTMGSNTPAKEICESGGLYLMCP-LCET--CKPWNMSDICPMAKVGYLFDHPGTVFFSVFMSLWAVTFLEYWKRKNATLAHHWDCMDFHEDEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMFETGSSVLRTQAGNIANISSTLVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLCIIMVGKQLINNIQEFVIPKIKAWRQKRALASVKKAQKTQEPERWEQDYELIPC-----------EGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWVEVRLDAHKFVCEYRRPVAERAQHIGVWFIILEALSHVSVVVNAFLIAFTSDFLPRLLYQYKFN--NDLHGYVNFTLAYSPPSYNHSS--HTVCRYKAFRD-----ENGKYKL--VYWELLAVRLGFIIAFEHVVFFVLRVIDWMVPDIPESLQLKIKRERYLAKQAL 879
[Close]
BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano3 (anoctamin 3 [Source:ZFIN;Acc:ZDB-GENE-111031-3])

HSP 1 Score: 332.413 bits (851), Expect = 3.558e-98
Identity = 269/900 (29.89%), Postives = 442/900 (49.11%), Query Frame = 3 
Query:  213 TNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTN---DKLTNMSLHNLISEQVFESAYCLHES-FIVQNSLKRD--ESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSD--VYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVA-FITQNQTDKGNESSVPFWRRT--VPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--------LKGFSDFTLSYLKSSEFASSTNET-YCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            T +GL F DG ++ID++L Y+K +     R     F + L  +GL  E +       SL N D       I+F+K+ A W+TLC YAE + IR P                   FRK   F  +   +  SR   F + F   K +L   P N                      ++ ++     L +++      +      M  F+  N E+  S S  +          +HH++Q     D  + M ++ L+    +E+A+  HE  +  ++ +K    ++ R  LY+ W       + QPLD IR YFGEKI  YF+WLG+YT  L   +L+GL + ++ +    S  +  EI E     MCP +C    C  W LSD  VY K  V  + DN   +  A  M+IWA++FLE WKR +  L + W++ D + + E  +P+F A +  + + +  +    PF   T  +  +    S + F + L L  +  ++++ ++     +      V +      S TG  I+ ++I+ L +VY K+A+ LT LE+  T+SE+++S  +K++L +F+N  S  FY  F L      PG   K  +  +   C   GCL  L +Q+  IM+ +Q+ ++F E  YPLL +   + K++       R+   +N   E+ +   D  L  + +  +  EYLEM++QFGF T+F+ AFPLAPLLAL NN++EIR DA KF+T ++RP+  R  DIG W  +L  +  +AV +NA +IA T+ +I R +Y +KY P  D        L+G+ + +LS     E  + + E  YCRY D+R  P   +  P   T  +W +LAA++ F+ +FE++V+ I   I+  IP+  + +   + +E  + ++++
Sbjct:  151 TPSGLMFRDGKKRIDYILVYKKSSPQVEKR---CTFERNLRAEGLMLEKEP------SLTNSD-------IMFVKIHAPWDTLCKYAEQMNIRMP-------------------FRKKCYFTDWKKKAMGSR---FQLRFRQLKSWL---PRN---------------------PMKLDKEA---LPDLVETDCYTAPFCRARMHHFTINNRETFFSNSTRSRI--------VHHVLQRTKYEDGKSKMGINRLLGNSTYEAAFPPHEGCYKSRHPIKTHGAQNHRHLLYERWARWGIWYKYQPLDLIRRYFGEKIGLYFAWLGWYTGMLIPAALVGLFVFLYGLFTMDSSQVSKEICEANTTVMCP-MCEG-NCSSWTLSDSCVYAK--VTHLFDNGGTVFFAIFMAIWATVFLEFWKRRRAELTYDWDLIDWEEEEEELRPQFEAKYSRKERVNPISGKPEPFQPLTDKLSRLMVSVSGIFFMISLVLTAVFAVVVFRLIAMEKFVSFQWEFVKKNWQFATSGTGVCINFMIIMSLNVVYEKVAYLLTNLEHPRTESEWENSFALKMFLFQFVNLNSSTFYIAFFLGRFAGRPGDYNKLFNRWRMEECHPSGCLIDLCLQMGVIMVLKQIWNNFMELGYPLLQNWWSRRKMK-------RAGEQSNSKEELPQWDRDWNLQPMNAHGLVDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGVLEGIGVVAVITNAFVIAITSDYIPRFVYAIKYGPCVDKGYRHEKCLRGYLNNSLSVFDMGELRNGSYENQYCRYRDYRAPPWSPE--PYEFTLQFWHVLAARLAFIIVFEHLVFGIKTFIAHMIPDMPKDLCDRMRREKYLMQEMV 964
[Close]
BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 330.872 bits (847), Expect = 4.435e-98
Identity = 226/645 (35.04%), Postives = 349/645 (54.11%), Query Frame = 3 
Query:  936 KLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESD---RVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNI-TMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFW--RRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKV-KYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            K   + +  L+ +  F  A+ LHE      S          R  LY  W      C+ QPLD IR YFGEKIA YF+WLGFYT WL   +L+G  + V  IL   S+    EI E G +  MCP LC +  CK W +SD+     V  + D+   +  +  MS+WA  FLE WKR+   LA HW+  D     EP +PEF A     + +       P++  +  +  M      ++  + + + FLV +I+Y  ++  ++    S ++   +  I +++ ++++L +ILL+  VY  LA  LT  E + TQ++Y+D+ T K+++ +F+N YS  FY  F        PG +  +  ++   C  GGCL  L+ QL  IM+G+QLI++  E+  P + +  +K  L    K  K +       + E+I C           + +F EYLE+++QFGFIT+F+ AFPLAPL AL NN +E+R DA KF+  Y+RPVA+R + IG W  IL  ++ ++V  NA LIAFT+ F+ RLLY  K++   DL G+ +FTL+Y   S   SS   T CRY  FR      +NG   L  +YWE+LA ++ F+  FE+VV+ ++++I   +P+  E +  +I +E  ++++ L
Sbjct:  260 KRAEVGVARLLRDGAFTGAFPLHEGPFKLPSCDTQPDQLNKRQVLYHYWASWLKWCKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAALVGTCVFVSGILTMGSNTPAKEICESGGLYLMCP-LCET--CKPWNMSDICPMAKVGYLFDHPGTVFFSVFMSLWAVTFLEYWKRKNATLAHHWDCMDFHEDEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMFETGSSVLRTQAGNIANISSTLVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLCIIMVGKQLINNIQEFVIPKIKAWRQKRALASVKKAQKTQEPERWEQDYELIPC-----------EGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWVEVRLDAHKFVCEYRRPVAERAQHIGVWFIILEALSHVSVVVNAFLIAFTSDFLPRLLYQYKFN--NDLHGYVNFTLAYSPPSYNHSS--HTVCRYKAFRD-----ENGKYKL--VYWELLAVRLGFIIAFEHVVFFVLRVIDWMVPDIPESLQLKIKRERYLAKQAL 879
[Close]
BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO5 (anoctamin 5 [Source:NCBI gene;Acc:100489787])

HSP 1 Score: 325.479 bits (833), Expect = 1.902e-96
Identity = 278/907 (30.65%), Postives = 431/907 (47.52%), Query Frame = 3 
Query:  213 TNNGLFFTDGIRQIDFVLAYQK--LNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYE--PQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFS--TVLFSVILALAFLVGIILYEIVIYAL--------LMMHP-SPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKA--MSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--LKGFSDFTLSYLKSSEFASST-------NETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            + + +FF DG R+IDFVL+Y +    D E+  + R +F   L K GLE E +D++             +  K  F+K+ A WE L  YAE+L ++ P+         E  LS         +F L      +     FT PF   K+ LF     R+ FF  + R+ IV YIL                                             S+ H   +E  +                   +  L++   +  AY LH+    + + +R+  +R  LY  W       + QPLD IR Y+GEKI  YF+WLGFYT  LF+ +++G    ++  +     I   EI +   GG I MCP LC+ K+C+FW+L+          + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+ +  T+ + +   +   P+   T     F FS  TVLF + L +A ++ II+Y + +YA         L + P S L+T    +  SVT S+++ + I++L  +Y ++A W+T +E   T  EY++ +TMK++L +F+N YS  FY  F        P   +      +   C   GCL  L+ QL  +M G+Q+  +  E   P   + +K+ K R   +  Y             R   D  L       +F EYLEM++QFGFIT+F+ +FPLAPLLAL NN+LEIR D+ K  T +KRPVA +   IG W  IL+ +A L+V +NA ++AFT+  I RL+Y   YS      + G+   +LS    S+F   +       N   CRY D+R+ P   K   +T+   YW ILAAK+ F+ + E+VV+ +   ++  IP+    +   + +E  +++K+L
Sbjct:   29 SKDSVFFWDGSRRIDFVLSYTEDTGKDAEKKAERRREFELNLQKSGLELETEDKK-----------ESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLKADDLKDDSENILS-----HVLKLFKLP-QEVMYPEPDYFTAPFRKDKQELFRT-EEREKFFTPSTRNRIVYYIL---------------------------------------------SRCHYGEEEGKK----------------KFGIKRLLTNGSYLDAYPLHDCQYWKKTDERN-CERYTLYTHWAKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMDDSISSKEICDPNIGGQIIMCP-LCD-KRCEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYESKCTEKKKNPVTQEMEPYLPATSKAARFCFSGATVLFWIALIIASIIAIIVYRLWVYAAFASIMDNNLALKPVSNLLTPQ--LATSVTASVLNFVTIMILNFLYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPADYSYLFGKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKRRKARNHPQNLYS------------RWEHDGDLQTFGGLGLFNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPMSGYIGSSLSVFNVSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQ--YWHILAAKMAFIIIMEHVVFLVKFFVAWLIPDVPSEVKARVKREKFLTQKIL 837
[Close]
BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO5 (anoctamin 5 [Source:NCBI gene;Acc:100489787])

HSP 1 Score: 323.939 bits (829), Expect = 6.576e-96
Identity = 283/907 (31.20%), Postives = 433/907 (47.74%), Query Frame = 3 
Query:  213 TNNGLFFTDGIRQIDFVLAYQK--LNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYE--PQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFS--TVLFSVILALAFLVGIILYEIVIYAL--------LMMHP-SPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKA--MSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--LKGFSDFTLSYLKSSEFASST-------NETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            + + +FF DG R+IDFVL+Y +    D E+  + R +F   L K GLE E +D++             +  K  F+K+ A WE L  YAE+L ++ P+         E  LS         +F L      +     FT PF   K+ LF     R+ FF  + R+ IV YIL                                             S+ H   +E  +    I  L      LTN S         +  AY LH+    + + +R+  +R  LY  W       + QPLD IR Y+GEKI  YF+WLGFYT  LF+ +++G    ++  +     I   EI +   GG I MCP LC+ K+C+FW+L+          + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+ +  T+ + +   +   P+   T     F FS  TVLF + L +A ++ II+Y + +YA         L + P S L+T    +  SVT S+++ + I++L  +Y ++A W+T +E   T  EY++ +TMK++L +F+N YS  FY  F        P   +      +   C   GCL  L+ QL  +M G+Q+  +  E   P   + +K+ K R   +  Y             R   D  L       +F EYLEM++QFGFIT+F+ +FPLAPLLAL NN+LEIR D+ K  T +KRPVA +   IG W  IL+ +A L+V +NA ++AFT+  I RL+Y   YS      + G+   +LS    S+F   +       N   CRY D+R+ P   K   +T+   YW ILAAK+ F+ + E+VV+ +   ++  IP+    +   + +E  +++K+L
Sbjct:   29 SKDSVFFWDGSRRIDFVLSYTEDTGKDAEKKAERRREFELNLQKSGLELETEDKK-----------ESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLKADDLKDDSENILS-----HVLKLFKLP-QEVMYPEPDYFTAPFRKDKQELFRT-EEREKFFTPSTRNRIVYYIL---------------------------------------------SRCHYGEEEGKKKFG-IKRL------LTNGS---------YLDAYPLHDCQYWKKTDERN-CERYTLYTHWAKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMDDSISSKEICDPNIGGQIIMCP-LCD-KRCEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYESKCTEKKKNPVTQEMEPYLPATSKAARFCFSGATVLFWIALIIASIIAIIVYRLWVYAAFASIMDNNLALKPVSNLLTPQ--LATSVTASVLNFVTIMILNFLYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPADYSYLFGKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKRRKARNHPQNLYS------------RWEHDGDLQTFGGLGLFNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPMSGYIGSSLSVFNVSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQ--YWHILAAKMAFIIIMEHVVFLVKFFVAWLIPDVPSEVKARVKREKFLTQKIL 837
[Close]
BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO5 (anoctamin 5 [Source:NCBI gene;Acc:100489787])

HSP 1 Score: 322.398 bits (825), Expect = 1.719e-95
Identity = 284/916 (31.00%), Postives = 430/916 (46.94%), Query Frame = 3 
Query:  195 RIPK-TTTNNGLFFTDGIRQIDFVLAYQK--LNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDES--DRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYE--PQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFS--TVLFSVILALAFLVGIILYEIVIYAL--------LMMHP-SPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKA--MSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--LKGFSDFTLSYLKSSEFASST-------NETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            RI K   + + +FF DG R+IDFVL+Y +    D E+  + R +F   L K GLE E +D++             +  K  F+K+ A WE L  YAE+L ++ P+         E  LS         +F L      +     FT PF   K+ LF     R+ FF  + R+ IV YIL                                             S+ H   +E  +    I  L+     L    LH+                   Q   K DE   +R  LY  W       + QPLD IR Y+GEKI  YF+WLGFYT  LF+ +++G    ++  +     I   EI +   GG I MCP LC+ K+C+FW+L+          + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+ +  T+ + +   +   P+   T     F FS  TVLF + L +A ++ II+Y + +YA         L + P S L+T    +  SVT S+++ + I++L  +Y ++A W+T +E   T  EY++ +TMK++L +F+N YS  FY  F        P   +      +   C   GCL  L+ QL  +M G+Q+  +  E   P   + +K+ K R   +  Y             R   D  L       +F EYLEM++QFGFIT+F+ +FPLAPLLAL NN+LEIR D+ K  T +KRPVA +   IG W  IL+ +A L+V +NA ++AFT+  I RL+Y   YS      + G+   +LS    S+F   +       N   CRY D+R+ P   K   +T+   YW ILAAK+ F+ + E+VV+ +   ++  IP+    +   + +E  +++K+L
Sbjct:   10 RIDKHAQSKDSVFFWDGSRRIDFVLSYTEDTGKDAEKKAERRREFELNLQKSGLELETEDKK-----------ESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLKADDLKDDSENILS-----HVLKLFKLP-QEVMYPEPDYFTAPFRKDKQELFRT-EEREKFFTPSTRNRIVYYIL---------------------------------------------SRCHYGEEEGKKKFG-IKRLLTNGSYLDAYPLHD------------------CQYWKKTDERNCERYTLYTHWAKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMDDSISSKEICDPNIGGQIIMCP-LCD-KRCEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYESKCTEKKKNPVTQEMEPYLPATSKAARFCFSGATVLFWIALIIASIIAIIVYRLWVYAAFASIMDNNLALKPVSNLLTPQ--LATSVTASVLNFVTIMILNFLYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPADYSYLFGKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKRRKARNHPQNLYS------------RWEHDGDLQTFGGLGLFNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPMSGYIGSSLSVFNVSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQ--YWHILAAKMAFIIIMEHVVFLVKFFVAWLIPDVPSEVKARVKREKFLTQKIL 825
[Close]
BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO4 (major histocompatibility complex class I-related gene protein-like [Source:Xenbase;Acc:XB-GENE-5756215])

HSP 1 Score: 321.242 bits (822), Expect = 2.449e-95
Identity = 269/905 (29.72%), Postives = 442/905 (48.84%), Query Frame = 3 
Query:  201 PKTTTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTF--TMPFSSSKEYLFDIPANRQY---FFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQT---NDKLTNMSLHNLISEQVFESAYCLHE-SFIVQNSLKRD--ESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFF---------KFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSP-TGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            P+    +GLFF DG R+ID++L Y+K +     R+I   F + +  +GL  E +       S+ N D       I+F+KL A WE L                    +Y + ++ R  FR+  I+ L+    F SR        P    KE + D+  N  Y   F  Q     I+N            NK     N     +T + I                                 +HH++Q     +    + L+ L++   +E+A+ LHE S+  +NS+K    E+ R  L++CW       + QPLD +R YFGEKI  YF+WLG+YT  LF  +++GL + ++ +    S  +  EI +  NITMCPL C+ K C + +LSD      V  + DN   +  A  M++WA++FLE WKR +  +A+ W++ D + + E  +P+F A  ++       E   P   +  P+  F           S + F + + +A + GI++Y +V  +        L+   ++ + +   ++     I++L  +Y ++A +LT LE   T+SE+++S T+K++L +F+N  S  FY  F L      PG   + ++  +   C   GCL  L +Q+  IM+ +Q  ++F E  YPL+ +   + KLR+ + +  ++         + +   D  L  +    +F EYLEM++QFGF T+F+ AFPLAPLLAL NN++EIR DA KF+T ++RP+A R KDIG W  IL  +  L+V +NA +IA T+ FI RL+Y  KY P  G  +      +S      F+S       RY D+R  P   +  P   T  +W +LAA++ F+ +FE++V+ I  +IS  IP+  + +   + +E  + ++++
Sbjct:   17 PEKNKTSGLFFNDGKRRIDYILVYRKTSLQSEKREI---FERNIRAEGLHLEKES------SIVNSD-------IIFVKLHAPWEVLG-------------------RYAELMNVRMPFRR-KIYYLHRRYKFMSRFRGLLPKKPMRLDKEKIPDLEENDCYTAPFSQQRIHHFIIN------------NKDTFFNN-----ATRTRI---------------------------------VHHILQRVKYEEGKNKIGLNRLLTNCTYEAAFPLHEGSYRSKNSIKTHGAENHRHLLFECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAIVGLFVFLYGMFTLDSCQVSREICQATNITMCPL-CD-KYCPYMRLSDSCIYAKVTHLFDNSATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKK------ERVNPISGKPEPYQAFADKCSRLVVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRN-NSQVATTGTAVCINFCIIMLLNLYERVALFLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGRPGAYLRLINKWRLEECHPSGCLIDLCLQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKLRQEHGIHGKTA--------LPQWEKDYNLQPINPYGLFEEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFITQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAVTSDFIPRLVYAYKYGPCAGQGRAGEKLIIS------FSS-------RYRDYRDPPSAPE--PYAYTLQFWHVLAARLAFIIVFEHLVFFIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 803
[Close]
BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO5 (anoctamin 5 [Source:NCBI gene;Acc:100489787])

HSP 1 Score: 321.627 bits (823), Expect = 4.097e-95
Identity = 281/909 (30.91%), Postives = 427/909 (46.97%), Query Frame = 3 
Query:  213 TNNGLFFTDGIRQIDFVLAYQK--LNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDES--DRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYE--PQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFS--TVLFSVILALAFLVGIILYEIVIYAL--------LMMHP-SPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKA--MSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--LKGFSDFTLSYLKSSEFASST-------NETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            + + +FF DG R+IDFVL+Y +    D E+  + R +F   L K GLE E +D++             +  K  F+K+ A WE L  YAE+L ++ P+         E  LS         +F L      +     FT PF   K+ LF     R+ FF  + R+ IV YIL                                             S+ H   +E  +    I  L+     L    LH+                   Q   K DE   +R  LY  W       + QPLD IR Y+GEKI  YF+WLGFYT  LF+ +++G    ++  +     I   EI +   GG I MCP LC+ K+C+FW+L+          + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+ +  T+ + +   +   P+   T     F FS  TVLF + L +A ++ II+Y + +YA         L + P S L+T    +  SVT S+++ + I++L  +Y ++A W+T +E   T  EY++ +TMK++L +F+N YS  FY  F        P   +      +   C   GCL  L+ QL  +M G+Q+  +  E   P   + +K+ K R   +  Y             R   D  L       +F EYLEM++QFGFIT+F+ +FPLAPLLAL NN+LEIR D+ K  T +KRPVA +   IG W  IL+ +A L+V +NA ++AFT+  I RL+Y   YS      + G+   +LS    S+F   +       N   CRY D+R+ P   K   +T+   YW ILAAK+ F+ + E+VV+ +   ++  IP+    +   + +E  +++K+L
Sbjct:   29 SKDSVFFWDGSRRIDFVLSYTEDTGKDAEKKAERRREFELNLQKSGLELETEDKK-----------ESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLKADDLKDDSENILS-----HVLKLFKLP-QEVMYPEPDYFTAPFRKDKQELFRT-EEREKFFTPSTRNRIVYYIL---------------------------------------------SRCHYGEEEGKKKFG-IKRLLTNGSYLDAYPLHD------------------CQYWKKTDERNCERYTLYTHWAKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMDDSISSKEICDPNIGGQIIMCP-LCD-KRCEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYESKCTEKKKNPVTQEMEPYLPATSKAARFCFSGATVLFWIALIIASIIAIIVYRLWVYAAFASIMDNNLALKPVSNLLTPQ--LATSVTASVLNFVTIMILNFLYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPADYSYLFGKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKRRKARNHPQNLYS------------RWEHDGDLQTFGGLGLFNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPMSGYIGSSLSVFNVSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQ--YWHILAAKMAFIIIMEHVVFLVKFFVAWLIPDVPSEVKARVKREKFLTQKIL 837
[Close]
BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano6 (anoctamin 6 [Source:MGI Symbol;Acc:MGI:2145890])

HSP 1 Score: 324.709 bits (831), Expect = 5.552e-96
Identity = 289/946 (30.55%), Postives = 452/946 (47.78%), Query Frame = 3 
Query:  174 FSTKDNE---RIPKTTTNNG----LFFTDGIRQIDFVLAYQ--------KLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVA---FITQNQTDKGNESSVPF--WRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYAL----LMMHPSP-------LVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKA--MSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYS--PTGD-----LKGFSDFTLSYLKSSEFASSTNE---------TYCRYMDFRH---HPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            F + +N+   R P+    NG    LFFTDG R+IDF+L Y+        K   NE+ ++ R  +   L+  GL+ E      +             +K+VF+K+ A WE LC YAE++ I+ P+   P+++K         +F K    N    +        FT PF  S+   F I  +R  FF    RS IV +IL  +  Q   N                      +  F                         I+ L+ +        LH+       E   C  E ++    L R+ +    +YK           QPLD IR Y+GEKI  YF+WLG+YT  L   +++G+   ++  L   +     E+ +   GG I MCP  C+ + C FW+L+        + I D+   ++ A  M +W +LFLE WKR Q  L + W+  +LQ Q E  +PE+ A    +  N+  +  E  +PF    + +       S V F ++L +A ++GII+Y + ++ +    L  +P+        L  QM     S+T SIIS I+I++L  +Y K+A  +T  E   TQ++Y++S+TMK++L +F+N YS  FY  F        PG     +   +   C  GGCL  L+ QL  IM G+ + ++  E   P + + I +Y            K ++       R   D  L  +    +FYEYLEM+IQFGF+T+F+ +FPLAPLLAL NN+LEIR DA K  T ++R V ++ +DIG W  I+  +A LAV +NA++IAFT+  I RL+Y   +S  P GD     + G+ + TLS    ++F ++  E         T CRY DFR+   HP + K+        YW ++AAK+ F+ + E+++Y++   IS  IP+ ++    +I +E  +++KLL
Sbjct:   38 FGSLENQQDFRTPEFEEFNGKPDSLFFTDGQRRIDFILVYEDESKKENNKKGTNEKQKRKRQAYESNLICHGLQLEATRSVSD-------------DKLVFVKVHAPWEVLCTYAEIMHIKLPL--KPNDLKTRSPFGNLNWFTKVLRVN---ESVIKPEQEFFTAPFEKSRMNDFYI-LDRDSFFNPATRSRIVYFILSRVKYQVMNN----------------------VNKFG------------------------INRLVSSGIYKAAFPLHDCRFNYESEDISCPSERYL----LYREWAHPRSIYK----------KQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLDQDNCTWSKEVCDPDIGGQILMCP-QCD-RLCPFWRLNITCESSKKLCIFDSFGTLIFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ-QEEQARPEYEAQCNHVVINEITQ-EEERIPFTTCGKCIRVTLCA-SAVFFWILLIIASVIGIIVYRLSVFIVFSTTLPKNPNGTDPIQKYLTPQM---ATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYLLGKYRSEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWVMNLIGRY------------KRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSIPPYGDHTYYTMDGYINNTLSVFNITDFKNTDKENPYIGLGNYTLCRYRDFRNPPGHPQEYKH-----NIYYWHVIAAKLAFIIVMEHIIYSVKFFISYAIPDVSKITKSKIKREKYLTQKLL 879
[Close]
BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano6 (anoctamin 6 [Source:MGI Symbol;Acc:MGI:2145890])

HSP 1 Score: 323.939 bits (829), Expect = 1.685e-95
Identity = 289/946 (30.55%), Postives = 452/946 (47.78%), Query Frame = 3 
Query:  174 FSTKDNE---RIPKTTTNNG----LFFTDGIRQIDFVLAYQ--------KLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVA---FITQNQTDKGNESSVPF--WRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYAL----LMMHPSP-------LVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKA--MSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYS--PTGD-----LKGFSDFTLSYLKSSEFASSTNE---------TYCRYMDFRH---HPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            F + +N+   R P+    NG    LFFTDG R+IDF+L Y+        K   NE+ ++ R  +   L+  GL+ E      +             +K+VF+K+ A WE LC YAE++ I+ P+   P+++K         +F K    N    +        FT PF  S+   F I  +R  FF    RS IV +IL  +  Q   N                      +  F                         I+ L+ +        LH+       E   C  E ++    L R+ +    +YK           QPLD IR Y+GEKI  YF+WLG+YT  L   +++G+   ++  L   +     E+ +   GG I MCP  C+ + C FW+L+        + I D+   ++ A  M +W +LFLE WKR Q  L + W+  +LQ Q E  +PE+ A    +  N+  +  E  +PF    + +       S V F ++L +A ++GII+Y + ++ +    L  +P+        L  QM     S+T SIIS I+I++L  +Y K+A  +T  E   TQ++Y++S+TMK++L +F+N YS  FY  F        PG     +   +   C  GGCL  L+ QL  IM G+ + ++  E   P + + I +Y            K ++       R   D  L  +    +FYEYLEM+IQFGF+T+F+ +FPLAPLLAL NN+LEIR DA K  T ++R V ++ +DIG W  I+  +A LAV +NA++IAFT+  I RL+Y   +S  P GD     + G+ + TLS    ++F ++  E         T CRY DFR+   HP + K+        YW ++AAK+ F+ + E+++Y++   IS  IP+ ++    +I +E  +++KLL
Sbjct:   59 FGSLENQQDFRTPEFEEFNGKPDSLFFTDGQRRIDFILVYEDESKKENNKKGTNEKQKRKRQAYESNLICHGLQLEATRSVSD-------------DKLVFVKVHAPWEVLCTYAEIMHIKLPL--KPNDLKTRSPFGNLNWFTKVLRVN---ESVIKPEQEFFTAPFEKSRMNDFYI-LDRDSFFNPATRSRIVYFILSRVKYQVMNN----------------------VNKFG------------------------INRLVSSGIYKAAFPLHDCRFNYESEDISCPSERYL----LYREWAHPRSIYK----------KQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLDQDNCTWSKEVCDPDIGGQILMCP-QCD-RLCPFWRLNITCESSKKLCIFDSFGTLIFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ-QEEQARPEYEAQCNHVVINEITQ-EEERIPFTTCGKCIRVTLCA-SAVFFWILLIIASVIGIIVYRLSVFIVFSTTLPKNPNGTDPIQKYLTPQM---ATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYLLGKYRSEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWVMNLIGRY------------KRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSIPPYGDHTYYTMDGYINNTLSVFNITDFKNTDKENPYIGLGNYTLCRYRDFRNPPGHPQEYKH-----NIYYWHVIAAKLAFIIVMEHIIYSVKFFISYAIPDVSKITKSKIKREKYLTQKLL 900
[Close]
BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano1 (anoctamin 1, calcium activated chloride channel [Source:MGI Symbol;Acc:MGI:2142149])

HSP 1 Score: 322.783 bits (826), Expect = 5.261e-95
Identity = 223/661 (33.74%), Postives = 358/661 (54.16%), Query Frame = 3 
Query:  945 NMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEI-KEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQ-----TDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLI-SHFTEYSYPLLCSSIKKYKLRKCNK------VKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNET----------YCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK 2852
            +M + +L++  V+ +AY LH+     ++++ +  DR  LY+ W       + QP+D +R YFGEK+  YF+WLG YT  L   S++G+++ ++       +I   E+  +  NITMCPL C+ K C +WK+S          + DN   +  +  M++WA+ F+E WKR+Q RL + W++   + + +  + E+ A + +        +K  +     WR   P  F    +++F + +  A ++G+I+Y I   A L M+ SP V     V ++ T  II+L+VI+LL  VY  +A WLT +E  +T+  +++ +T K +LL+F+N+Y+ +FY  F        PG         +   C  GGCL  L +QL+ IM+G+QLI ++  E   P +   I+  KLR+ +       VK + +   + N E          A L       EY+EM+IQFGF+T+F+ +FPLAPL AL NN++EIR DA KF+T  +RPVA R KDIG W NIL  V  LAV  NA +I+FT+ FI RL+Y+  YS  G + GF + TLS    S+F + T              CRY D+R  P         ++  +W +LAA++ FV +F+N+V  +   +   IP+  + I+++I KE  +  +L ++
Sbjct:  265 SMGITSLLANGVYSAAYPLHDGDYEGDNVEFN--DRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPL-CD-KTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLRKESRNKETDKVKLTWRDRFPAYFTNLVSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQSPSDREEYVKRKQRYEVDFNLEP--------FAGLTP-----EYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPW--SEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMR 906
[Close]
BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano1 (anoctamin 1, calcium activated chloride channel [Source:MGI Symbol;Acc:MGI:2142149])

HSP 1 Score: 322.783 bits (826), Expect = 1.800e-94
Identity = 223/661 (33.74%), Postives = 358/661 (54.16%), Query Frame = 3 
Query:  945 NMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEI-KEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFI-----TQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLI-SHFTEYSYPLLCSSIKKYKLRKCNK------VKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNET----------YCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK 2852
            +M + +L++  V+ +AY LH+     ++++ +  DR  LY+ W       + QP+D +R YFGEK+  YF+WLG YT  L   S++G+++ ++       +I   E+  +  NITMCPL C+ K C +WK+S          + DN   +  +  M++WA+ F+E WKR+Q RL + W++   + + +  + E+ A +      +   +K  +     WR   P  F    +++F + +  A ++G+I+Y I   A L M+ SP V     V ++ T  II+L+VI+LL  VY  +A WLT +E  +T+  +++ +T K +LL+F+N+Y+ +FY  F        PG         +   C  GGCL  L +QL+ IM+G+QLI ++  E   P +   I+  KLR+ +       VK + +   + N E          A L       EY+EM+IQFGF+T+F+ +FPLAPL AL NN++EIR DA KF+T  +RPVA R KDIG W NIL  V  LAV  NA +I+FT+ FI RL+Y+  YS  G + GF + TLS    S+F + T              CRY D+R  P         ++  +W +LAA++ FV +F+N+V  +   +   IP+  + I+++I KE  +  +L ++
Sbjct:  323 SMGITSLLANGVYSAAYPLHDGDYEGDNVEFN--DRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPL-CD-KTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLRKESRNKETDKVKLTWRDRFPAYFTNLVSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQSPSDREEYVKRKQRYEVDFNLEP--------FAGLTP-----EYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPW--SEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMR 964
[Close]
BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano1 (anoctamin 1, calcium activated chloride channel [Source:MGI Symbol;Acc:MGI:2142149])

HSP 1 Score: 319.316 bits (817), Expect = 3.218e-93
Identity = 225/665 (33.83%), Postives = 358/665 (53.83%), Query Frame = 3 
Query:  945 NMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEI-KEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQK----PEFVAFI-----TQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLI-SHFTEYSYPLLCSSIKKYKLRKCNK------VKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNET----------YCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK 2852
            +M + +L++  V+ +AY LH+     ++++ +  DR  LY+ W       + QP+D +R YFGEK+  YF+WLG YT  L   S++G+++ ++       +I   E+  +  NITMCPL C+ K C +WK+S          + DN   +  +  M++WA+ F+E WKR+Q RL + W++   + + E  K     E+ A +      +   +K  +     WR   P  F    +++F + +  A ++G+I+Y I   A L M+ SP V     V ++ T  II+L+VI+LL  VY  +A WLT +E  +T+  +++ +T K +LL+F+N+Y+ +FY  F        PG         +   C  GGCL  L +QL+ IM+G+QLI ++  E   P +   I+  KLR+ +       VK + +   + N E          A L       EY+EM+IQFGF+T+F+ +FPLAPL AL NN++EIR DA KF+T  +RPVA R KDIG W NIL  V  LAV  NA +I+FT+ FI RL+Y+  YS  G + GF + TLS    S+F + T              CRY D+R  P         ++  +W +LAA++ FV +F+N+V  +   +   IP+  + I+++I KE  +  +L ++
Sbjct:  322 SMGITSLLANGVYSAAYPLHDGDYEGDNVEFN--DRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPL-CD-KTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLRKESRNKETDKVKLTWRDRFPAYFTNLVSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQSPSDREEYVKRKQRYEVDFNLEP--------FAGLTP-----EYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPW--SEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMR 967
[Close]
BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q4KMQ2|ANO6_HUMAN (Anoctamin-6 OS=Homo sapiens OX=9606 GN=ANO6 PE=1 SV=2)

HSP 1 Score: 339.732 bits (870), Expect = 1.213e-100
Identity = 292/935 (31.23%), Postives = 456/935 (48.77%), Query Frame = 3 
Query:  195 RIPKTTTNNG----LFFTDGIRQIDFVLAYQ--------KLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFG---NSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDK--GNESSVPF--WRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL-------MMHPSPLVTQMX-XXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKA--MSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYS--PTGD-----LKGFSDFTLSYLKSSEFASST---------NETYCRYMDFRH---HPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            R P+    NG    LFF DG R+IDFVL Y+        K   NE+ R+ R  +   L+  GL+ E      +             +K+VF+K+ A WE LC YAE++ I+ P+   P+++K   S      F   + F        +        FT PF  ++   F I  +R  FF    RS IV +IL  +  Q                                IN+ S+                 I+ L+ +        LH+    +  E   C +E ++              LY+ W   R+I + QPLD IR Y+GEKI  YF+WLG+YT  L   +++G+   ++  L+  +     E+     GG I MCP  C+ + C FWKL+        + I D+   ++ A  M +W +LFLE WKR Q  L + W+  +LQ Q E  +PE+ A  T    ++    E  +PF  W + +       S V F ++L +A ++GII+Y + ++ +        +    P+   ++     S+T SIIS I+I++L  +Y K+A  +T  E   TQ++Y++S+TMK++L +F+N YS  FY  F        PG     +   +   C  GGCL  L+ QL  IM G+ + ++  E   P + + I ++     ++V   S+ IT       R   D  L  +    +FYEYLEM+IQFGF+T+F+ +FPLAPLLAL NN+LEIR DA K  T ++R V ++ +DIG W  I+  +A LAV +NA++IAFT+  I RL+Y   +S  P GD     ++G+ + TLS  K ++F + +         N T CRY DFR+   HP + K+        YW ++AAK+ F+ + E+V+Y++   IS  IP+ ++R   +I +E  +++KLL
Sbjct:   46 RTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLD-------------DKLVFVKVHAPWEVLCTYAEIMHIKLPL--KPNDLKNRSSA-----FGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYI-VDRDAFFNPATRSRIVYFILSRVKYQ-------------------------------VINNVSKFG---------------INRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYL--------------LYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCP-QCD-RLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ-QEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCA-SAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRF-----HRVS-GSEKITP------RWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKH-----NIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLL 878
[Close]
BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q6P9J9|ANO6_MOUSE (Anoctamin-6 OS=Mus musculus OX=10090 GN=Ano6 PE=1 SV=1)

HSP 1 Score: 324.709 bits (831), Expect = 3.884e-95
Identity = 289/946 (30.55%), Postives = 452/946 (47.78%), Query Frame = 3 
Query:  174 FSTKDNE---RIPKTTTNNG----LFFTDGIRQIDFVLAYQ--------KLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVA---FITQNQTDKGNESSVPF--WRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYAL----LMMHPSP-------LVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKA--MSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYS--PTGD-----LKGFSDFTLSYLKSSEFASSTNE---------TYCRYMDFRH---HPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            F + +N+   R P+    NG    LFFTDG R+IDF+L Y+        K   NE+ ++ R  +   L+  GL+ E      +             +K+VF+K+ A WE LC YAE++ I+ P+   P+++K         +F K    N    +        FT PF  S+   F I  +R  FF    RS IV +IL  +  Q   N                      +  F                         I+ L+ +        LH+       E   C  E ++    L R+ +    +YK           QPLD IR Y+GEKI  YF+WLG+YT  L   +++G+   ++  L   +     E+ +   GG I MCP  C+ + C FW+L+        + I D+   ++ A  M +W +LFLE WKR Q  L + W+  +LQ Q E  +PE+ A    +  N+  +  E  +PF    + +       S V F ++L +A ++GII+Y + ++ +    L  +P+        L  QM     S+T SIIS I+I++L  +Y K+A  +T  E   TQ++Y++S+TMK++L +F+N YS  FY  F        PG     +   +   C  GGCL  L+ QL  IM G+ + ++  E   P + + I +Y            K ++       R   D  L  +    +FYEYLEM+IQFGF+T+F+ +FPLAPLLAL NN+LEIR DA K  T ++R V ++ +DIG W  I+  +A LAV +NA++IAFT+  I RL+Y   +S  P GD     + G+ + TLS    ++F ++  E         T CRY DFR+   HP + K+        YW ++AAK+ F+ + E+++Y++   IS  IP+ ++    +I +E  +++KLL
Sbjct:   38 FGSLENQQDFRTPEFEEFNGKPDSLFFTDGQRRIDFILVYEDESKKENNKKGTNEKQKRKRQAYESNLICHGLQLEATRSVSD-------------DKLVFVKVHAPWEVLCTYAEIMHIKLPL--KPNDLKTRSPFGNLNWFTKVLRVN---ESVIKPEQEFFTAPFEKSRMNDFYI-LDRDSFFNPATRSRIVYFILSRVKYQVMNN----------------------VNKFG------------------------INRLVSSGIYKAAFPLHDCRFNYESEDISCPSERYL----LYREWAHPRSIYK----------KQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLDQDNCTWSKEVCDPDIGGQILMCP-QCD-RLCPFWRLNITCESSKKLCIFDSFGTLIFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ-QEEQARPEYEAQCNHVVINEITQ-EEERIPFTTCGKCIRVTLCA-SAVFFWILLIIASVIGIIVYRLSVFIVFSTTLPKNPNGTDPIQKYLTPQM---ATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYLLGKYRSEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWVMNLIGRY------------KRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSIPPYGDHTYYTMDGYINNTLSVFNITDFKNTDKENPYIGLGNYTLCRYRDFRNPPGHPQEYKH-----NIYYWHVIAAKLAFIIVMEHIIYSVKFFISYAIPDVSKITKSKIKREKYLTQKLL 879
[Close]
BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q32M45|ANO4_HUMAN (Anoctamin-4 OS=Homo sapiens OX=9606 GN=ANO4 PE=2 SV=1)

HSP 1 Score: 324.324 bits (830), Expect = 1.045e-94
Identity = 273/924 (29.55%), Postives = 451/924 (48.81%), Query Frame = 3 
Query:  189 NERIPKTTTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNI--KYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHE-SFIVQNSLKRD--ESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSD--VYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFF---------KFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--------LKGFSDFTLSYLKSSEFA------------SSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
             E +P+   +NGL+F DG  +ID++L Y+K N     R++   F + +  +GL+ E +       SL N D       I+F+K                     LH P  +  +Y + ++ R                         MPF     YL      R+Y F+      I  +  R +  +  R     L ++       +  ++  +  F   N E+       NN      +  I   I+  +    + L+ L++   +E+A+ LHE S+  +NS++    E+ R  LY+CW       + QPLD +R YFGEKI  YF+WLG+YT  LF  + +GL + ++ +       +  E+ +  +I MCP +C+ K C F +LSD  VY K  V  + DN   +  A  M++WA++FLE WKR +  +A+ W++ D + + E  +P+F A  ++       E   P   +  P+  F           S + F + + +A + GI++Y +V  +        L+   S V  + T   I+  +I+LL ++Y K+A  LT LE   T+SE+++S T+K++L +F+N  S  FY  F L      PG   + ++  +   C   GCL  L +Q+  IM+ +Q  ++F E  YPL+ +   + K+R+ +  +   + I+    E      D  L  + +  +F EYLEM++QFGF T+F+ AFPLAPLLAL NN++EIR DA KF+T ++RP+A R KDIG W  IL  +  L+V +NA +IA T+ FI RL+Y  KY P           + G+ + +LS  + S+F             S T   YCRY D+R  P  +   P   T  +W +LAA++ F+ +FE++V+ I  +IS  IP+  + +   + +E  + ++++
Sbjct:   98 GETVPERNKSNGLYFRDGKCRIDYILVYRKSNPQTEKREV---FERNIRAEGLQMEKES------SLINSD-------IIFVK---------------------LHAPWEVLGRYAEQMNVR-------------------------MPFRRKIYYL-----PRRYKFMSRIDKQISRF-RRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKET-----FFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDIIMCP-VCD-KYCPFMRLSDSCVYAK--VTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSK------KERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPE---RKISFPQWE-----KDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLV--PYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM 928
[Close]
BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q8BHY3|ANO1_MOUSE (Anoctamin-1 OS=Mus musculus OX=10090 GN=Ano1 PE=1 SV=2)

HSP 1 Score: 319.316 bits (817), Expect = 8.192e-93
Identity = 225/665 (33.83%), Postives = 358/665 (53.83%), Query Frame = 3 
Query:  945 NMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEI-KEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQK----PEFVAFITQNQ-----TDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLI-SHFTEYSYPLLCSSIKKYKLRKCNK------VKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNET----------YCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK 2852
            +M + +L++  V+ +AY LH+     ++++ +  DR  LY+ W       + QP+D +R YFGEK+  YF+WLG YT  L   S++G+++ ++       +I   E+  +  NITMCPL C+ K C +WK+S          + DN   +  +  M++WA+ F+E WKR+Q RL + W++   + + E  K     E+ A + +        +K  +     WR   P  F    +++F + +  A ++G+I+Y I   A L M+ SP V     V ++ T  II+L+VI+LL  VY  +A WLT +E  +T+  +++ +T K +LL+F+N+Y+ +FY  F        PG         +   C  GGCL  L +QL+ IM+G+QLI ++  E   P +   I+  KLR+ +       VK + +   + N E          A L       EY+EM+IQFGF+T+F+ +FPLAPL AL NN++EIR DA KF+T  +RPVA R KDIG W NIL  V  LAV  NA +I+FT+ FI RL+Y+  YS  G + GF + TLS    S+F + T              CRY D+R  P         ++  +W +LAA++ FV +F+N+V  +   +   IP+  + I+++I KE  +  +L ++
Sbjct:  265 SMGITSLLANGVYSAAYPLHDGDYEGDNVEFN--DRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPL-CD-KTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLRKESRNKETDKVKLTWRDRFPAYFTNLVSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQSPSDREEYVKRKQRYEVDFNLEP--------FAGLTP-----EYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPW--SEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMR 910
[Close]
BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q9NQ90|ANO2_HUMAN (Anoctamin-2 OS=Homo sapiens OX=9606 GN=ANO2 PE=1 SV=2)

HSP 1 Score: 315.464 bits (807), Expect = 3.594e-91
Identity = 258/869 (29.69%), Postives = 415/869 (47.76%), Query Frame = 3 
Query:  399 DNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLS--FRKYFRKFDI-FNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNI-TMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQ----NQYEPQKPEFVAFITQNQTDKGNESSVP------------------FWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLI-SHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQP---VFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNE---------TYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK*NSR*QHEKF 2882
            D  + ++  +F+++ A W+ L   AE L+I+ P       IK   S++  F    +K             +++    + PFS  K YL++I   +  FF    RS IV+ IL+       R  C                                   S +NN                      M +++LI+  ++E+AY LH+     +S + D +DR  LY+ W       + QP+D IR YFGEKI  YF+WLG YT +L   S++G+++ ++       DI   E+ +  N  TMCPL C+ K C +W LS          + DN   +  +  M++WA++FLE WKR Q RL + W++  ++       E  +PE+   + +    + N+S+V                    W+   P     F+++LF + L  + + G+I+Y I   A L ++ +        V ++ T  II+L+VIL+L  +Y  +A WLT +E  +T+  +++ + +K +LL+F+N YS +FY  F        PG         +   C  GGCL  L +QL+ IM+G+QLI ++  E   P L    +K K       +  +    + +++    +D     D   +P   +  EY+EM+IQFGF+T+F+ +FPLAP+ AL NN++E+R DA KF+T  +RP A R KDIG W +ILS +   +V SNA +IA T+ FI RL+Y   YS  G L GF + TLS+   S+    T            +CR+ D+R  P      P   +  YW IL+A++ FV +F+N+V  +  ++   IP+    I+ +I KE ++     LK     +HEK 
Sbjct:  176 DLENKSQGSIFVRIHAPWQVLAREAEFLKIKVPTKKEMYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLYNI-QEKDTFFDNATRSRIVHEILK-------RTAC-----------------------------------SRANN---------------------TMGINSLIANNIYEAAYPLHDG--EYDSPEDDMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFLYGCATIEEDIPSREMCDQQNAFTMCPL-CD-KSCDYWNLSSACGTAQASHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKA--TRSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLK------DETEAGETDSAHSKHPEQWD----LDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPW--APNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLK----EEHEKL 958
[Close]
BLAST of Anoctamin vs. TrEMBL
Match: A0A5K4FF50 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 538.11 bits (1385), Expect = 2.378e-171
Identity = 325/840 (38.69%), Postives = 494/840 (58.81%), Query Frame = 3 
Query:  417 EKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDE-SDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE-GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGN------ESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYK-LRKCNKVKYRSKNITNVN--------------------AEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLL 2849
            + +VF+KL A WE + +YAE L++RKP+       K          F+ F        N        +T PFS +++YLFDIP N+  FF   ER+L++++ILR    + + +  N   ++  P                   S S+   SH   DE      + + L     K  N+ +  LIS+ +F +AY LHE     ++L   E ++R+ L + W   + + + QP+  IR YFGE +AFYF+WLGFYT WL   ++LG+++ +F +L   SD I++E+ + G NI MCP LC S +CKFW L     +  ++R++D++  +L A  MS+WA +F EMWKR+Q  LA+ WNVY L+   +P +PEF+A +++    K N      E  +PFWRR VP +   FSTVL +VIL LAFLVG++LY++VI  +L  H +P+V   + +I ++TGS+++L+ I  L +VY ++A  LT +E++ TQ EYD+S+T+KLYLL+F+N YS +FY  FI      +PG + +  ++  GC  G CLF L +QL  IM+G+Q+ S   E   P+L     K++ +++ +     + N+ ++N                       I C  D  + D  S+P+F EYLEM+IQ+GFITMF+PAFPLAPL  L NNL EIR DA K +  Y+RPV +RV+ IG W++I++V+A +A+++NA +IAFTT FI+R +Y   YSP G +KGF +FTLSY+ ++ F   TNETYCRY  +R  P    + P   TSIY+ +LAAK IFV+ FE +   +  +I A +P+  +R+ ++I  E  I+  ++L
Sbjct:  150 DNLVFVKLHASWEAMTYYAEYLKMRKPLRQLAYGWKLVNPTPKTSVFKDFLKCLRMDKNIIKPIDTCYTWPFSMNRQYLFDIPENKDEFFTAVERALVLDHILRRTGYK-SEDLVNT-EDLYEP-------------------SISDIVTSHDLADENSGSSNQANSLYVMATK--NLGITKLISDGIFSAAYPLHEP--AGSTLAPTEFNNRILLQRYWASYKMLFKCQPISYIRYYFGEAVAFYFAWLGFYTAWLLPIAILGIIVFLFGLLDLKSDSIIHEVCDLGQNIYMCP-LCKSSKCKFWTLDTSCLRTKLMRLVDHEGTVLFAVVMSLWAVIFFEMWKRKQVSLAYRWNVYSLEPMDQPPRPEFMALLSKRCPRKVNSLTGYVEPFIPFWRRKVPIILVSFSTVLLTVILTLAFLVGVVLYKLVIKVILYRHHNPIVQSTAGMIATMTGSLVNLVTIFFLKLVYDRMATKLTDIEHHRTQVEYDNSLTLKLYLLQFVNYYSSIFYIAFIQGPTSAVPGSEHIL-IQSTGCDQGDCLFELFIQLVIIMVGKQIFSFIQESLMPVLWKLFFKFRSMKRSSNYADHNHNMNSINFNESNPVTTSLLPAKYSSLSGRNILCRADFNMLDPGSRPLFNEYLEMMIQYGFITMFVPAFPLAPLFGLLNNLFEIRGDAKKLVNQYRRPVLERVQTIGIWLSIITVLASIAIRTNACIIAFTTQFIDRCVYRYTYSPDGTMKGFVNFTLSYMSTTRFDVPTNETYCRYDSYRSPPW--SSEPYVFTSIYYHVLAAKFIFVFTFETIATILTNVIMAAVPDVPKRVRRKIFHESNITNAIIL 960
[Close]
BLAST of Anoctamin vs. TrEMBL
Match: A0A5K4FDS2 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 530.791 bits (1366), Expect = 2.481e-168
Identity = 329/859 (38.30%), Postives = 497/859 (57.86%), Query Frame = 3 
Query:  417 EKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHE-----SFIV--QN------------SLKRDE-SDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE-GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGN------ESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYK-LRKCNKVKYRSKNITNVN--------------------AEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLL 2849
            + +VF+KL A WE + +YAE L++RKP+       K          F+ F        N        +T PFS +++YLFDIP N+  FF   ER+L++++ILR    + + +  N   ++  P                   S S+   SH   DE      + + L     K  N+ +  LIS+ +F +AY LHE     S I   QN            +L   E ++R+ L + W   + + + QP+  IR YFGE +AFYF+WLGFYT WL   ++LG+++ +F +L   SD I++E+ + G NI MCP LC S +CKFW L     +  ++R++D++  +L A  MS+WA +F EMWKR+Q  LA+ WNVY L+   +P +PEF+A +++    K N      E  +PFWRR VP +   FSTVL +VIL LAFLVG++LY++VI  +L  H +P+V   + +I ++TGS+++L+ I  L +VY ++A  LT +E++ TQ EYD+S+T+KLYLL+F+N YS +FY  FI      +PG + +  ++  GC  G CLF L +QL  IM+G+Q+ S   E   P+L     K++ +++ +     + N+ ++N                       I C  D  + D  S+P+F EYLEM+IQ+GFITMF+PAFPLAPL  L NNL EIR DA K +  Y+RPV +RV+ IG W++I++V+A +A+++NA +IAFTT FI+R +Y   YSP G +KGF +FTLSY+ ++ F   TNETYCRY  +R  P    + P   TSIY+ +LAAK IFV+ FE +   +  +I A +P+  +R+ ++I  E  I+  ++L
Sbjct:  150 DNLVFVKLHASWEAMTYYAEYLKMRKPLRQLAYGWKLVNPTPKTSVFKDFLKCLRMDKNIIKPIDTCYTWPFSMNRQYLFDIPENKDEFFTAVERALVLDHILRRTGYK-SEDLVNT-EDLYEP-------------------SISDIVTSHDLADENSGSSNQANSLYVMATK--NLGITKLISDGIFSAAYPLHEPTKKLSLITLQQNIITPSCYGPAGSTLAPTEFNNRILLQRYWASYKMLFKCQPISYIRYYFGEAVAFYFAWLGFYTAWLLPIAILGIIVFLFGLLDLKSDSIIHEVCDLGQNIYMCP-LCKSSKCKFWTLDTSCLRTKLMRLVDHEGTVLFAVVMSLWAVIFFEMWKRKQVSLAYRWNVYSLEPMDQPPRPEFMALLSKRCPRKVNSLTGYVEPFIPFWRRKVPIILVSFSTVLLTVILTLAFLVGVVLYKLVIKVILYRHHNPIVQSTAGMIATMTGSLVNLVTIFFLKLVYDRMATKLTDIEHHRTQVEYDNSLTLKLYLLQFVNYYSSIFYIAFIQGPTSAVPGSEHIL-IQSTGCDQGDCLFELFIQLVIIMVGKQIFSFIQESLMPVLWKLFFKFRSMKRSSNYADHNHNMNSINFNESNPVTTSLLPAKYSSLSGRNILCRADFNMLDPGSRPLFNEYLEMMIQYGFITMFVPAFPLAPLFGLLNNLFEIRGDAKKLVNQYRRPVLERVQTIGIWLSIITVLASIAIRTNACIIAFTTQFIDRCVYRYTYSPDGTMKGFVNFTLSYMSTTRFDVPTNETYCRYDSYRSPPW--SSEPYVFTSIYYHVLAAKFIFVFTFETIATILTNVIMAAVPDVPKRVRRKIFHESNITNAIIL 981
[Close]
BLAST of Anoctamin vs. TrEMBL
Match: A0A5K4FBC0 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 528.865 bits (1361), Expect = 9.292e-168
Identity = 329/861 (38.21%), Postives = 503/861 (58.42%), Query Frame = 3 
Query:  417 EKIVFIKLFAKWETLCHYAELLRIRKPI--LHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHE-----SFIV--QN------------SLKRDE-SDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE-GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGN------ESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYK-LRKCNKVKYRSKNITNVN--------------------AEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLL 2849
            + +VF+KL A WE + +YAE L++RKP+  L  P+     ++  F+ + +   +      N        +T PFS +++YLFDIP N+  FF   ER+L++++ILR    + + +  N   ++  P                   S S+   SH   DE      + + L     K  N+ +  LIS+ +F +AY LHE     S I   QN            +L   E ++R+ L + W   + + + QP+  IR YFGE +AFYF+WLGFYT WL   ++LG+++ +F +L   SD I++E+ + G NI MCP LC S +CKFW L     +  ++R++D++  +L A  MS+WA +F EMWKR+Q  LA+ WNVY L+   +P +PEF+A +++    K N      E  +PFWRR VP +   FSTVL +VIL LAFLVG++LY++VI  +L  H +P+V   + +I ++TGS+++L+ I  L +VY ++A  LT +E++ TQ EYD+S+T+KLYLL+F+N YS +FY  FI      +PG + +  ++  GC  G CLF L +QL  IM+G+Q+ S   E   P+L     K++ +++ +     + N+ ++N                       I C  D  + D  S+P+F EYLEM+IQ+GFITMF+PAFPLAPL  L NNL EIR DA K +  Y+RPV +RV+ IG W++I++V+A +A+++NA +IAFTT FI+R +Y   YSP G +KGF +FTLSY+ ++ F   TNETYCRY  +R  P    + P   TSIY+ +LAAK IFV+ FE +   +  +I A +P+  +R+ ++I  E  I+  ++L
Sbjct:  150 DNLVFVKLHASWEAMTYYAEYLKMRKPLRQLVNPT----PKTSVFKDFLKCLRMDK----NIIKPIDTCYTWPFSMNRQYLFDIPENKDEFFTAVERALVLDHILRRTGYK-SEDLVNT-EDLYEP-------------------SISDIVTSHDLADENSGSSNQANSLYVMATK--NLGITKLISDGIFSAAYPLHEPTKKLSLITLQQNIITPSCYGPAGSTLAPTEFNNRILLQRYWASYKMLFKCQPISYIRYYFGEAVAFYFAWLGFYTAWLLPIAILGIIVFLFGLLDLKSDSIIHEVCDLGQNIYMCP-LCKSSKCKFWTLDTSCLRTKLMRLVDHEGTVLFAVVMSLWAVIFFEMWKRKQVSLAYRWNVYSLEPMDQPPRPEFMALLSKRCPRKVNSLTGYVEPFIPFWRRKVPIILVSFSTVLLTVILTLAFLVGVVLYKLVIKVILYRHHNPIVQSTAGMIATMTGSLVNLVTIFFLKLVYDRMATKLTDIEHHRTQVEYDNSLTLKLYLLQFVNYYSSIFYIAFIQGPTSAVPGSEHIL-IQSTGCDQGDCLFELFIQLVIIMVGKQIFSFIQESLMPVLWKLFFKFRSMKRSSNYADHNHNMNSINFNESNPVTTSLLPAKYSSLSGRNILCRADFNMLDPGSRPLFNEYLEMMIQYGFITMFVPAFPLAPLFGLLNNLFEIRGDAKKLVNQYRRPVLERVQTIGIWLSIITVLASIAIRTNACIIAFTTQFIDRCVYRYTYSPDGTMKGFVNFTLSYMSTTRFDVPTNETYCRYDSYRSPPW--SSEPYVFTSIYYHVLAAKFIFVFTFETIATILTNVIMAAVPDVPKRVRRKIFHESNITNAIIL 975
[Close]
BLAST of Anoctamin vs. TrEMBL
Match: A0A564Y2W1 (Anoctamin OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS2493 PE=3 SV=1)

HSP 1 Score: 499.975 bits (1286), Expect = 3.268e-157
Identity = 353/974 (36.24%), Postives = 524/974 (53.80%), Query Frame = 3 
Query:  210 TTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSK---FLKILMKQGLEFEIQDEEGNL----------------FSLEN-------------FDNRDDT----------EKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHE-SFIVQNSLK-RDESD---------------RVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEI-KEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQ-------NQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLL--CSSIKKYKLRKCNKVKYRSKN----------------ITNVNAEII-RCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEF-------ASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK 2852
            +T+  +FF DG R+ID+VL Y+   D E +  I+SK   FL  L +Q +E E+++  G +                F LE+             +D+ DDT          + +VF+KL A W TL   AE+L+ RKP+      +K E+ L  ++  +    F+L   N F      +  PF+ ++  LF++P +   FF  +ERSL+V++IL+          C ++          ++    ++ T   +N E          +ET   L ++  +   N    ++ + ++I+E+VF +A+ LHE S  +   LK R+ES                R  L   WG  + + + QPLD IR YFGE IAFYF+WLG YTYWL    + GL++   + +  S D IV +I   GG I MCP  CN K C+ W L+   +   +  ++DN   +L A  M+IWA+LF+E WKR Q  LA  WNV  L++  EP +PEF+A I +       N      E +VPFW R +P     F++VLF V+L LA L+G+I Y +V+  LL+   +  ++ ++ +I ++T S I+L+ I +L  +Y K+A  LT +EN+ TQSEYDDS+T+KLYLL+F+N YS +FY  FI      +PG  ++  ++  GC  G CLF L +QLA IM+G+Q ++  TE + P +  C S+   + R   +    ++N                +   N  I+  C  +  L D  S+P+F EYLEMLIQ+GFITMF+PAFP+APL ALFNN+ E+R DA KFL   +RP+ +R K IG W  ILSVV+ LA+++NA LIAFT+ F+ER+ Y+  YSP  +L G+ DF+LSY+  S F       A   N TYCRY DFR  P      P   T +YW  LA K  FV++FENV   +  +I+  IP+  E +      E  +  +LLL+
Sbjct:   40 STSREMFFQDGKRRIDYVLVYR---DGEMDDNIKSKRYAFLTALAEQMIEIEVENCRGEIVAKTGPQSAGFKEDAAFLLEHMESSHGALGPDWQYDSDDDTNPLEAAIRAHQDLVFVKLHATWSTLIRVAEVLQFRKPL----KQVKVER-LELQEGVKCSSCFDLDKKNIFK-LPAPYRAPFTRARMSLFEVPEDYDQFFTPSERSLVVDFILKRT------GTCGLIPRPWAAGEGENAEAGHQIITEDEVNFE----------NETRAKLDDVKLV---NRGKVDLGIDHMINEKVFLTAFPLHEPSHELLELLKSREESTPPTSSAPTYTVENNMRTLLTNQWGSLKMMLKFQPLDYIRLYFGESIAFYFAWLGLYTYWLIPVGIFGLLVFCLSAIDISDDRIVEDICNGGGEIVMCPT-CN-KGCRLWLLNASCFSAKMTHLVDNLGTVLFAIFMAIWATLFMENWKRYQNVLAHRWNVNLLESVDEPPRPEFLALIKKRGYKTSINPVTGREEPTVPFWSRKLPIATLSFASVLFGVLLCLATLIGVIFYRLVVNTLLLQSENVFISTVAGMITTITSSCINLVFIFILKFIYDKIAVKLTDMENHRTQSEYDDSLTLKLYLLQFVNLYSSIFYIAFIQGTTASLPGDDSVP-IRSSGCDNGNCLFQLFIQLAIIMVGKQFLNFITENTIPPIKRCLSVYFARRRSSKERNTITENPPHYGSIETGEPERAPLKGANRPILYNCRLNYTLLDGGSRPLFDEYLEMLIQYGFITMFVPAFPIAPLFALFNNMFELRTDAKKFLRLMRRPIIKREKGIGIWYGILSVVSSLAIRTNACLIAFTSEFLERMNYVFYYSPNRNLDGYVDFSLSYMNVSRFTLNAKDEALLGNSTYCRYRDFREPP--TAADPYAYTPVYWHNLAVKFAFVFIFENVAIALCALIAKCIPDMPESLIIISRHEARVINELLLQ 980
[Close]
BLAST of Anoctamin vs. TrEMBL
Match: A0A564Y474 (Anoctamin OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS2493 PE=3 SV=1)

HSP 1 Score: 499.975 bits (1286), Expect = 3.970e-157
Identity = 353/974 (36.24%), Postives = 524/974 (53.80%), Query Frame = 3 
Query:  210 TTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSK---FLKILMKQGLEFEIQDEEGNL----------------FSLEN-------------FDNRDDT----------EKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHE-SFIVQNSLK-RDESD---------------RVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEI-KEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQ-------NQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLL--CSSIKKYKLRKCNKVKYRSKN----------------ITNVNAEII-RCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEF-------ASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK 2852
            +T+  +FF DG R+ID+VL Y+   D E +  I+SK   FL  L +Q +E E+++  G +                F LE+             +D+ DDT          + +VF+KL A W TL   AE+L+ RKP+      +K E+ L  ++  +    F+L   N F      +  PF+ ++  LF++P +   FF  +ERSL+V++IL+          C ++          ++    ++ T   +N E          +ET   L ++  +   N    ++ + ++I+E+VF +A+ LHE S  +   LK R+ES                R  L   WG  + + + QPLD IR YFGE IAFYF+WLG YTYWL    + GL++   + +  S D IV +I   GG I MCP  CN K C+ W L+   +   +  ++DN   +L A  M+IWA+LF+E WKR Q  LA  WNV  L++  EP +PEF+A I +       N      E +VPFW R +P     F++VLF V+L LA L+G+I Y +V+  LL+   +  ++ ++ +I ++T S I+L+ I +L  +Y K+A  LT +EN+ TQSEYDDS+T+KLYLL+F+N YS +FY  FI      +PG  ++  ++  GC  G CLF L +QLA IM+G+Q ++  TE + P +  C S+   + R   +    ++N                +   N  I+  C  +  L D  S+P+F EYLEMLIQ+GFITMF+PAFP+APL ALFNN+ E+R DA KFL   +RP+ +R K IG W  ILSVV+ LA+++NA LIAFT+ F+ER+ Y+  YSP  +L G+ DF+LSY+  S F       A   N TYCRY DFR  P      P   T +YW  LA K  FV++FENV   +  +I+  IP+  E +      E  +  +LLL+
Sbjct:   40 STSREMFFQDGKRRIDYVLVYR---DGEMDDNIKSKRYAFLTALAEQMIEIEVENCRGEIVAKTGPQSAGFKEDAAFLLEHMESSHGALGPDWQYDSDDDTNPLEAAIRAHQDLVFVKLHATWSTLIRVAEVLQFRKPL----KQVKVER-LELQEGVKCSSCFDLDKKNIFK-LPAPYRAPFTRARMSLFEVPEDYDQFFTPSERSLVVDFILKRT------GTCGLIPRPWAAGEGENAEAGHQIITEDEVNFE----------NETRAKLDDVKLV---NRGKVDLGIDHMINEKVFLTAFPLHEPSHELLELLKSREESTPPTSSAPTYTVENNMRTLLTNQWGSLKMMLKFQPLDYIRLYFGESIAFYFAWLGLYTYWLIPVGIFGLLVFCLSAIDISDDRIVEDICNGGGEIVMCPT-CN-KGCRLWLLNASCFSAKMTHLVDNLGTVLFAIFMAIWATLFMENWKRYQNVLAHRWNVNLLESVDEPPRPEFLALIKKRGYKTSINPVTGREEPTVPFWSRKLPIATLSFASVLFGVLLCLATLIGVIFYRLVVNTLLLQSENVFISTVAGMITTITSSCINLVFIFILKFIYDKIAVKLTDMENHRTQSEYDDSLTLKLYLLQFVNLYSSIFYIAFIQGTTASLPGDDSVP-IRSSGCDNGNCLFQLFIQLAIIMVGKQFLNFITENTIPPIKRCLSVYFARRRSSKERNTITENPPHYGSIETGEPERAPLKGANRPILYNCRLNYTLLDGGSRPLFDEYLEMLIQYGFITMFVPAFPIAPLFALFNNMFELRTDAKKFLRLMRRPIIKREKGIGIWYGILSVVSSLAIRTNACLIAFTSEFLERMNYVFYYSPNRNLDGYVDFSLSYMNVSRFTLNAKDEALLGNSTYCRYRDFREPP--TAADPYAYTPVYWHNLAVKFAFVFIFENVAIALCALIAKCIPDMPESLIIISRHEARVINELLLQ 980
[Close]
BLAST of Anoctamin vs. Ensembl Cavefish
Match: ano5b (anoctamin 5b [Source:ZFIN;Acc:ZDB-GENE-061215-108])

HSP 1 Score: 355.14 bits (910), Expect = 3.575e-107
Identity = 287/917 (31.30%), Postives = 451/917 (49.18%), Query Frame = 3 
Query:  216 NNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSF--RKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHES-FIVQNSLKRDESDRVKLYKCWGLTRNIC--RSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNV--YDLQNQYEPQKPEFVAFITQ---NQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL--MMHPSP-----LVTQMXXXXXXXXXXXXXXXXXXXXXX--XYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG---FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--LKGFSDFTLSYLKSSEFAS-------------STNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
             + ++F DG R+IDFVL+Y    D ++  + R  F   L K GL  E++D+           +  D  K  ++K+ A WE L  +A++L+I+ P      +   E SL++  R +    DI +        S    FT PF   K   F I  +++ FF  + R+ IV YIL                                          + C     +  E D+                   +  L+S   + SAY LH+  +  +      ES+R  LYK W   R +C  + QPL+ IR Y+GEKI  YF+WLGFYT  LFF +++G++  V+ +L    +I   EI +   GG I MCPL C+ K+C +WKL+      +   + DN+  +  A  M IW +LFLE WKR Q RL + W++  ++ + Q    +PEF    T    N   +  E  +P   +   F F   +TVLF   L +A ++G+I Y + +YA    +M  SP     LV  + N  ++ + +   +  +++L +  +Y  +A W+T +E  +T  EY++ +T K+++ +F+N YS  FY  F        PG   +   S L+   C  GGCL  L+ QL  +M+G+QL+ +  E   PLL    K + + +        K  ++   +  R   D  L       +FYEYLEM+IQFGFIT+F+ +FPLAPLLALFNN+LE+R DA KF T ++RPVA + ++IG W  IL+VVA L+V +NA ++AFT+  I RL+Y+  Y P  +  + G+ + +LS  + S+                + N T CRY D+R+ P   +    T T  +W ILAAK+ F+ + E+VV+ +   ++  IP+    +   I +E  + ++ L
Sbjct:   68 KDSVYFRDGKRRIDFVLSYVDDKDGDKKAERRRLFEANLEKTGLHLELEDK-----------SESDDRKTYYLKIHAPWEVLGTFADVLKIKVPFKASDIHKAREGSLNWLTRPFRLPPDIMS--------SEPDYFTAPFDKRKADFFLI-KDQETFFPPSTRNRIVYYIL------------------------------------------THCPYYKEDRKEKDK-----------------TGIKRLLSNSTYTSAYPLHDCRYWKKADQTLCESERYHLYKHWA--RFLCFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLFFAAVVGVICFVYGLLSYDDNITSKEICDPTIGGKIVMCPL-CD-KKCSYWKLNSTCLSSWQAHLFDNEGTVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVHFEEEQQQLQMRPEFELKCTNKRLNPITQEMEPYLPLTSKCARF-FVSGATVLFWTCLIVACIMGVIAYRLAVYAAFARLMKDSPTSKIQLVGSLINPQLATSVTASCINFVIILILNFLYEHVAIWITDMEIPKTHLEYENKLTTKMFMFQFVNYYSSCFYVAFFKGKFVGYPGKYTYMFGSHLRNEECAPGGCLIELTTQLVIVMVGKQLVGNIQEALLPLL----KNWWISR--------KGRSHPEGQYSRWEQDHDLQSFSQFGLFYEYLEMVIQFGFITLFVASFPLAPLLALFNNILEVRLDAWKFTTQFRRPVAAKARNIGAWNEILNVVAILSVVTNAFIMAFTSDMIPRLVYLYAYHPGEEATMAGYINNSLSVYEISDLRVNNRPDEEENPAWFNANITTCRYRDYRYPPGHHRQ--YTHTMQFWHILAAKMAFIIIMEHVVFVVKFFVAWLIPDVPSEVKARIKRERHLVQEYL 886
[Close]
BLAST of Anoctamin vs. Ensembl Cavefish
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:103044829])

HSP 1 Score: 342.043 bits (876), Expect = 9.040e-103
Identity = 273/918 (29.74%), Postives = 439/918 (47.82%), Query Frame = 3 
Query:  213 TNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSK-FLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKP--ILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHES-FIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQ--KPEFVAFITQNQTDKGNESSVPFWRRT--VPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL--MMHPSP-----LVTQMXXXXXXXXXXXXXXXXXXXXXXX--YAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAM---SDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDL--KGFSDFTLSYLKSSEFASSTNE--------------TYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            + + ++F DG R+IDFVL+Y  + D E  ++ R K + + + K GLE E++D+              +  K  F+K+ A WE L  YA++L+I+ P  +   P N +   S  F           L   +        FT PF  SK+  F I  +++  F  + R+ IV YIL                                          S C  +  +N   D+                   +  L++   + SA+ LH+  +  ++     ES+R  LY+ W       + QPL+ IR Y+GEKI  YF+WLGFYT  LF+ +L+GL+  ++        I   EI +   GG I MCPL C+ K+C FWKL+      +   + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+    T  + +K  +   P++  T          +TVLF + L +A ++G+I Y + ++A L  +M  SP     LV  +    ++ + +   +  ++++ +   Y ++A W+T +E  +T  EY++ +T+K++L +F+N YS  FY  F        PG +  M   S L+   C  GGCL  L+ QL  +M G+Q+  +  E   P L +     K R   +  Y             R   D  L +     +FYEYLEM+IQFGFIT+F+ +FPLAPLLAL NN+LE+R DA K  T ++RPVA +   IG W  IL+++A  +V +NA ++AFT+  I RL+Y+  Y P  +L  +G+ + +LS    S+  S                  T CRY D+R+ P        + T  +W ILAAK+ F+ + E+VV+ +  +++  IP+    +   + +E  + ++ L
Sbjct:   18 SKDSVYFRDGKRRIDFVLSY--IEDKEDRKQERRKLYEENMQKAGLELELEDK-----------TESEDGKTYFLKIHAPWEVLATYADVLKIKVPFKVNDIPENREIPVSWLFTPL--------LLPDHVMRPDPDYFTSPFDKSKDDFFLI-DDKETLFPPSTRNRIVYYIL------------------------------------------SRCFYNRDDNINKDK-----------------RGIKRLLNNGTYTSAFPLHDCRYWTKSRDTHCESERYSLYRYWARFFRFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLFYAALVGLICFIYGAATYDDVIWTKEICDDDIGGQIVMCPL-CD-KKCGFWKLNSTCNSTWQSHLFDNTATVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCTSRRRNKVTQEMEPYFPVTSKCARACLSGATVLFWISLIIASIIGVIAYRLAVFAALASVMKDSPTNKMELVGSLITPQLATSVTASCINFVIIMILNFFYERVAIWITDMEVPKTHLEYENKLTIKMFLFQFVNYYSSCFYVAFFKGKFVGYPGKYTYMFNGSGLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALLPWLKNWWSSRKARSHPESLYS------------RWEQDYDLQNFSQFGLFYEYLEMVIQFGFITLFVASFPLAPLLALMNNILEVRVDAWKLTTQFRRPVAAKAHSIGAWDEILNMIAVFSVVTNAFIVAFTSDMIPRLVYLYAYHPGTELTMQGYVNNSLSIFNISQLHSDNTPDPGENPAWFNNSVITTCRYRDYRYPPG--HEYEYSHTMQFWHILAAKMAFIIIMEHVVFVVKFLVAWLIPDVPSDVQARVKRERYLVQEYL 838
[Close]
BLAST of Anoctamin vs. Ensembl Cavefish
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:103044829])

HSP 1 Score: 342.043 bits (876), Expect = 1.024e-102
Identity = 273/918 (29.74%), Postives = 439/918 (47.82%), Query Frame = 3 
Query:  213 TNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSK-FLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKP--ILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHES-FIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQ--KPEFVAFITQNQTDKGNESSVPFWRRT--VPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL--MMHPSP-----LVTQMXXXXXXXXXXXXXXXXXXXXXXX--YAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAM---SDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDL--KGFSDFTLSYLKSSEFASSTNE--------------TYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            + + ++F DG R+IDFVL+Y  + D E  ++ R K + + + K GLE E++D+              +  K  F+K+ A WE L  YA++L+I+ P  +   P N +   S  F           L   +        FT PF  SK+  F I  +++  F  + R+ IV YIL                                          S C  +  +N   D+                   +  L++   + SA+ LH+  +  ++     ES+R  LY+ W       + QPL+ IR Y+GEKI  YF+WLGFYT  LF+ +L+GL+  ++        I   EI +   GG I MCPL C+ K+C FWKL+      +   + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+    T  + +K  +   P++  T          +TVLF + L +A ++G+I Y + ++A L  +M  SP     LV  +    ++ + +   +  ++++ +   Y ++A W+T +E  +T  EY++ +T+K++L +F+N YS  FY  F        PG +  M   S L+   C  GGCL  L+ QL  +M G+Q+  +  E   P L +     K R   +  Y             R   D  L +     +FYEYLEM+IQFGFIT+F+ +FPLAPLLAL NN+LE+R DA K  T ++RPVA +   IG W  IL+++A  +V +NA ++AFT+  I RL+Y+  Y P  +L  +G+ + +LS    S+  S                  T CRY D+R+ P        T+   +W ILAAK+ F+ + E+VV+ +  +++  IP+    +   + +E  + ++ L
Sbjct:   23 SKDSVYFRDGKRRIDFVLSY--IEDKEDRKQERRKLYEENMQKAGLELELEDK-----------TESEDGKTYFLKIHAPWEVLATYADVLKIKVPFKVNDIPENREIPVSWLFTPL--------LLPDHVMRPDPDYFTSPFDKSKDDFFLI-DDKETLFPPSTRNRIVYYIL------------------------------------------SRCFYNRDDNINKDK-----------------RGIKRLLNNGTYTSAFPLHDCRYWTKSRDTHCESERYSLYRYWARFFRFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLFYAALVGLICFIYGAATYDDVIWTKEICDDDIGGQIVMCPL-CD-KKCGFWKLNSTCNSTWQSHLFDNTATVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCTSRRRNKVTQEMEPYFPVTSKCARACLSGATVLFWISLIIASIIGVIAYRLAVFAALASVMKDSPTNKMELVGSLITPQLATSVTASCINFVIIMILNFFYERVAIWITDMEVPKTHLEYENKLTIKMFLFQFVNYYSSCFYVAFFKGKFVGYPGKYTYMFNGSGLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALLPWLKNWWSSRKARSHPESLYS------------RWEQDYDLQNFSQFGLFYEYLEMVIQFGFITLFVASFPLAPLLALMNNILEVRVDAWKLTTQFRRPVAAKAHSIGAWDEILNMIAVFSVVTNAFIVAFTSDMIPRLVYLYAYHPGTELTMQGYVNNSLSIFNISQLHSDNTPDPGENPAWFNNSVITTCRYRDYRYPPGHEYEYSHTMQ--FWHILAAKMAFIIIMEHVVFVVKFLVAWLIPDVPSDVQARVKRERYLVQEYL 843
[Close]
BLAST of Anoctamin vs. Ensembl Cavefish
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:103044829])

HSP 1 Score: 341.658 bits (875), Expect = 2.209e-102
Identity = 273/918 (29.74%), Postives = 439/918 (47.82%), Query Frame = 3 
Query:  213 TNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSK-FLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKP--ILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHES-FIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQ--KPEFVAFITQNQTDKGNESSVPFWRRT--VPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL--MMHPSP-----LVTQMXXXXXXXXXXXXXXXXXXXXXXX--YAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAM---SDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDL--KGFSDFTLSYLKSSEFASSTNE--------------TYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            + + ++F DG R+IDFVL+Y  + D E  ++ R K + + + K GLE E++D+              +  K  F+K+ A WE L  YA++L+I+ P  +   P N +   S  F           L   +        FT PF  SK+  F I  +++  F  + R+ IV YIL                                          S C  +  +N   D+                   +  L++   + SA+ LH+  +  ++     ES+R  LY+ W       + QPL+ IR Y+GEKI  YF+WLGFYT  LF+ +L+GL+  ++        I   EI +   GG I MCPL C+ K+C FWKL+      +   + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+    T  + +K  +   P++  T          +TVLF + L +A ++G+I Y + ++A L  +M  SP     LV  +    ++ + +   +  ++++ +   Y ++A W+T +E  +T  EY++ +T+K++L +F+N YS  FY  F        PG +  M   S L+   C  GGCL  L+ QL  +M G+Q+  +  E   P L +     K R   +  Y             R   D  L +     +FYEYLEM+IQFGFIT+F+ +FPLAPLLAL NN+LE+R DA K  T ++RPVA +   IG W  IL+++A  +V +NA ++AFT+  I RL+Y+  Y P  +L  +G+ + +LS    S+  S                  T CRY D+R+ P        T+   +W ILAAK+ F+ + E+VV+ +  +++  IP+    +   + +E  + ++ L
Sbjct:   52 SKDSVYFRDGKRRIDFVLSY--IEDKEDRKQERRKLYEENMQKAGLELELEDK-----------TESEDGKTYFLKIHAPWEVLATYADVLKIKVPFKVNDIPENREIPVSWLFTPL--------LLPDHVMRPDPDYFTSPFDKSKDDFFLI-DDKETLFPPSTRNRIVYYIL------------------------------------------SRCFYNRDDNINKDK-----------------RGIKRLLNNGTYTSAFPLHDCRYWTKSRDTHCESERYSLYRYWARFFRFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLFYAALVGLICFIYGAATYDDVIWTKEICDDDIGGQIVMCPL-CD-KKCGFWKLNSTCNSTWQSHLFDNTATVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCTSRRRNKVTQEMEPYFPVTSKCARACLSGATVLFWISLIIASIIGVIAYRLAVFAALASVMKDSPTNKMELVGSLITPQLATSVTASCINFVIIMILNFFYERVAIWITDMEVPKTHLEYENKLTIKMFLFQFVNYYSSCFYVAFFKGKFVGYPGKYTYMFNGSGLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALLPWLKNWWSSRKARSHPESLYS------------RWEQDYDLQNFSQFGLFYEYLEMVIQFGFITLFVASFPLAPLLALMNNILEVRVDAWKLTTQFRRPVAAKAHSIGAWDEILNMIAVFSVVTNAFIVAFTSDMIPRLVYLYAYHPGTELTMQGYVNNSLSIFNISQLHSDNTPDPGENPAWFNNSVITTCRYRDYRYPPGHEYEYSHTMQ--FWHILAAKMAFIIIMEHVVFVVKFLVAWLIPDVPSDVQARVKRERYLVQEYL 872
[Close]
BLAST of Anoctamin vs. Ensembl Cavefish
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:103044829])

HSP 1 Score: 341.658 bits (875), Expect = 3.170e-102
Identity = 273/918 (29.74%), Postives = 439/918 (47.82%), Query Frame = 3 
Query:  213 TNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSK-FLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKP--ILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHES-FIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE---GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQ--KPEFVAFITQNQTDKGNESSVPFWRRT--VPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL--MMHPSP-----LVTQMXXXXXXXXXXXXXXXXXXXXXXX--YAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAM---SDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDL--KGFSDFTLSYLKSSEFASSTNE--------------TYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            + + ++F DG R+IDFVL+Y  + D E  ++ R K + + + K GLE E++D+              +  K  F+K+ A WE L  YA++L+I+ P  +   P N +   S  F           L   +        FT PF  SK+  F I  +++  F  + R+ IV YIL                                          S C  +  +N   D+                   +  L++   + SA+ LH+  +  ++     ES+R  LY+ W       + QPL+ IR Y+GEKI  YF+WLGFYT  LF+ +L+GL+  ++        I   EI +   GG I MCPL C+ K+C FWKL+      +   + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+    T  + +K  +   P++  T          +TVLF + L +A ++G+I Y + ++A L  +M  SP     LV  +    ++ + +   +  ++++ +   Y ++A W+T +E  +T  EY++ +T+K++L +F+N YS  FY  F        PG +  M   S L+   C  GGCL  L+ QL  +M G+Q+  +  E   P L +     K R   +  Y             R   D  L +     +FYEYLEM+IQFGFIT+F+ +FPLAPLLAL NN+LE+R DA K  T ++RPVA +   IG W  IL+++A  +V +NA ++AFT+  I RL+Y+  Y P  +L  +G+ + +LS    S+  S                  T CRY D+R+ P        T+   +W ILAAK+ F+ + E+VV+ +  +++  IP+    +   + +E  + ++ L
Sbjct:   66 SKDSVYFRDGKRRIDFVLSY--IEDKEDRKQERRKLYEENMQKAGLELELEDK-----------TESEDGKTYFLKIHAPWEVLATYADVLKIKVPFKVNDIPENREIPVSWLFTPL--------LLPDHVMRPDPDYFTSPFDKSKDDFFLI-DDKETLFPPSTRNRIVYYIL------------------------------------------SRCFYNRDDNINKDK-----------------RGIKRLLNNGTYTSAFPLHDCRYWTKSRDTHCESERYSLYRYWARFFRFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLFYAALVGLICFIYGAATYDDVIWTKEICDDDIGGQIVMCPL-CD-KKCGFWKLNSTCNSTWQSHLFDNTATVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCTSRRRNKVTQEMEPYFPVTSKCARACLSGATVLFWISLIIASIIGVIAYRLAVFAALASVMKDSPTNKMELVGSLITPQLATSVTASCINFVIIMILNFFYERVAIWITDMEVPKTHLEYENKLTIKMFLFQFVNYYSSCFYVAFFKGKFVGYPGKYTYMFNGSGLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALLPWLKNWWSSRKARSHPESLYS------------RWEQDYDLQNFSQFGLFYEYLEMVIQFGFITLFVASFPLAPLLALMNNILEVRVDAWKLTTQFRRPVAAKAHSIGAWDEILNMIAVFSVVTNAFIVAFTSDMIPRLVYLYAYHPGTELTMQGYVNNSLSIFNISQLHSDNTPDPGENPAWFNNSVITTCRYRDYRYPPGHEYEYSHTMQ--FWHILAAKMAFIIIMEHVVFVVKFLVAWLIPDVPSDVQARVKRERYLVQEYL 886
[Close]
BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 308.145 bits (788), Expect = 7.970e-92
Identity = 232/650 (35.69%), Postives = 360/650 (55.38%), Query Frame = 3 
Query:  936 KLTNMSLHNLISEQVFESAYCLHESFIVQNSLK---RDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWL-GFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE-GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWR------RTVPFMFFKFSTVLFSVI-LALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            K   + L  ++ + +F +A+ LHE       L       + R  LYK W       + QPLD IR YFGEKIAFYF+WL GFYT WL  P+L+GLV+     L   +D  V EI E G +  MCPL C++  CK W LS+      +  I D    I  +  +S+W+  FLE WKR+   L +HW    L ++ E  +PE+ A     + +       P++       RTV       S VLF +I + L FLV +ILY+ ++   +    +  +   +  I ++TG+++ L++I+++  +Y  +A +LT  E + TQSE+++++T+K+++ + +N YS   Y GF        PG +  +   +   CP GGCL  L+ QL  IM+G+Q++++  E   P++    ++ KL +      R K +     E+    DD  L  L +  +F EYLEM++QFGFIT+F+ AFPLAPL AL NN +EIR DA KF+  Y+R V +RV+ IG W +ILS +A +++ SNA LIAFT+ F+ RLLY  +Y+    L G+ DFTL+Y       +  N T CRY DFR      ++G LTL   YW++LA ++ FV +FE++V+ + + I   I +    +  +I +E  ++++ L
Sbjct:  161 KKAEVGLDRMLRDHIFSAAFPLHEGSYDGTYLGLAPEQMTRRQVLYKYWARWGCWFKYQPLDHIREYFGEKIAFYFAWLLGFYTCWLLPPALVGLVVFFVGWLTLHNDSTVKEICENGSHYQMCPL-CDT--CKVWNLSNTCNMAKMGHIFDYPGTIFYSIFISLWSVSFLEYWKRKSSSLTYHWGC-TLVHEEERPRPEYAALAPLIRENPITGEKEPYFSEDDRTPRTV-----TGSIVLFLMISVVLIFLVTVILYQALLSISIFKTGNWFLATQATNIANMTGTLVFLVLIVIMARLYTTIADYLTRWEMHRTQSEHENALTVKVFIFQLVNYYSSPVYVGFFKGKFNGYPGNYGNLFGTRNENCPQGGCLIELAQQLFIIMVGKQILNNLQELILPIIQQWRQRRKLDEI-----RGKRLVQ---ELNIWEDDYEL--LHNTGLFDEYLEMVMQFGFITIFVMAFPLAPLFALMNNWVEIRLDARKFVCRYRRSVVERVRGIGVWFDILSGLAHISIISNAFLIAFTSDFLPRLLY--RYTYKSSLDGYVDFTLAYAPRDYVVA--NHTMCRYRDFRD-----QDGNLTL--FYWKLLAVRLSFVIIFEHLVFLVARAIDWLIVDVAPDLKVKIKREEYLAKQAL 780
[Close]
BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000399.1 (pep scaffold:Pmarinus_7.0:GL477564:2673:43187:-1 gene:ENSPMAG00000000358.1 transcript:ENSPMAT00000000399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 296.975 bits (759), Expect = 1.181e-87
Identity = 211/595 (35.46%), Postives = 329/595 (55.29%), Query Frame = 3 
Query:  906 EIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKE-GGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQ-------TDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLI-SHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLA--DLESQP---VFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASS----TNETYCRY 2630
            EI   ++       M + +LI+  V+ SA+ LH+  +  + +    +DR  L+  W       + QPL+ I+ YFGEKI  YF+WLG YT  L  PS++G+ + ++  L A  DI   E    G NITMCP  C+ K CK+ +LS+   +     + DN T +L +  M++WA+ FLE WKR + RL + W++  ++   +  +PE+ A + + +            E     WR  +P      S +LF V+L+ A +VG+I Y I +  LL     P +    + II  T  +I+L++IL+L  +Y  +A WLT +E  +T+ E++  +  K ++L+F+N+Y+ + Y  F+   I   P   +  + + +   C  GGCL  L++QL  IM+G+QL+ ++  E   P     IKK         +Y  K   +  A  ++  D + L   D E +P   +  EY+EM+IQFGF+T+F+ +FPLAP  AL NN++EIR D  KF+T  +RP A R KDIGTW  IL+ VA LAV  NA++IA T+ F+ RL+Y+  YSP G L+G+ ++TLSY   S++A      +N T CRY
Sbjct:  213 EILKRVKCTKGPYKMGITSLIANGVYTSAFPLHDGELHGSEV----NDRKLLHDEWASYNKFYKYQPLELIKKYFGEKIGLYFAWLGVYTQMLIPPSVVGIAVFLYGWLAAEKDIPGFETCVIGQNITMCPT-CD-KLCKYKRLSENCDRVRSSHLFDNITTVLFSIFMALWATTFLEHWKRIETRLNYTWDLNGMEESEQQLRPEYEAKLLEKKRKVDIKLAKTQTEEYGLSWRDQLPSFLINCSCILFMVLLSFAIVVGMIFYRITMNVLLANSTDPYLKSNRSAIIMATAFLINLVIILILDEIYGSIARWLTVIEVPKTEEEFETRLIFKSFMLKFVNSYTSIIYVAFLKGRITGYPKKYYYILPNYRMEECAPGGCLQELALQLCIIMLGKQLLQNNLFEVGIP----KIKKL-------CRYLHKKDHHKKASHLKEEDGMELGCKDYELEPFTGLNPEYMEMVIQFGFVTLFVASFPLAPFFALLNNVIEIRLDGKKFVTELRRPTAVRAKDIGTWYVILNGVAKLAVIINALVIALTSDFVPRLIYMYFYSPDGSLRGYVNYTLSYFNVSDYAPGIIIESNYTLCRY 790
[Close]
BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 199.904 bits (507), Expect = 1.309e-56
Identity = 152/411 (36.98%), Postives = 243/411 (59.12%), Query Frame = 3 
Query: 1641 LALAFLVGIILYE-IVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRK-----CNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEM--LIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            + + FLV +I+Y  IV   +     + L+TQ +  I +++ S+++LI+IL++  VY+ LA  LT  E + TQ++Y+D+ T K+++ +F+N YS  FY  F        PG +K +   +   C  GGCL  L+ QL  IM+G+Q+I++  E+ +PL          R+       K K  +   ++V  E  R  +D  L   E   +F EYLEM  ++QFGFIT+F+ AFPLAPL AL NN +E+R DA KF+  Y+RPVA+R +DIG W NIL  +  ++V  NA LIAFT+ F+ +LLY  +Y+   +L+G+ +FTLSY       +  N T+CRY D+R      ++G  TL   YW++LA ++ F+  FE+VV+ I ++I   +P+  E +  ++ +E  ++++ L
Sbjct:    5 VVMIFLVTVIMYRGIVSVVMYKTGNAVLMTQQAANIANISSSMVNLILILVMGQVYSSLAEQLTKWEMHRTQTQYEDAFTFKVFVFQFVNFYSSPFYVAFFKGRFVGYPGHYKKLLGTRNEDCGPGGCLIELAQQLIIIMVGKQVINNIQEFVFPLTLPPPAPRSCRRKIKAWLQKRKLAALRGSHVAPESSRWEEDYELIPCEG--LFEEYLEMGPVLQFGFITIFVAAFPLAPLFALLNNWVELRLDAQKFVCEYRRPVAERAQDIGVWFNILDALVNISVIINAFLIAFTSNFLPKLLY--QYTYDRNLRGYINFTLSYAPDDYVVN--NYTHCRYKDYRD-----QDGKHTL--FYWKLLAIRLGFIIAFEHVVFFISRMIDWLVPDVPESLEIKMKRERYLAKQAL 402
[Close]
BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 198.749 bits (504), Expect = 3.411e-56
Identity = 146/412 (35.44%), Postives = 246/412 (59.71%), Query Frame = 3 
Query: 1620 TVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEM--LIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
             ++  + + + FLV +I+Y  ++  ++    + ++   +  I +++ S+++LI+IL++  VY+ LA  LT  E + TQ++Y+D+ T K+++ +F+N YS  FY  F        PG +K +   +   C  GGCL  L+ QL  IM+G+Q+I++  E+ +P + + ++K KL             ++V  E  R  +D  L   E   +F EYLEM  ++QFGFIT+F+ AFPLAPL AL NN +E+R DA KF+  Y+RPVA+R +DIG W NIL  +  ++V  NA LIAFT+ F+ +LLY  +Y+   +L+G+ +FTLSY       +  N T+CRY D+R      ++G  TL   YW++LA ++ F+  FE+VV+ I ++I   +P+  E +  ++ +E  ++++ L
Sbjct:    4 VIILMLSVVMIFLVTVIMYRGIVSVVMYKTGNAVLMTQAANIANISSSMVNLILILVMGQVYSSLAEQLTKWEMHRTQTQYEDAFTFKVFVFQFVNFYSSPFYVAFFKGRFVGYPGHYKKLLGTRNEDCGPGGCLIELAQQLIIIMVGKQVINNIQEFVFPKIKAWLQKRKLAALRG--------SHVAPESSRWEEDYELIPCEG--LFEEYLEMGPVLQFGFITIFVAAFPLAPLFALLNNWVELRLDAQKFVCEYRRPVAERAQDIGVWFNILDALVNISVIINAFLIAFTSNFLPKLLY--QYTYDRNLRGYINFTLSYAPDDYVVN--NYTHCRYKDYRD-----QDGKHTL--FYWKLLAIRLGFIIAFEHVVFFISRMIDWLVPDVPESLEIKMKRERYLAKQAL 394
[Close]
BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 194.512 bits (493), Expect = 1.288e-54
Identity = 148/412 (35.92%), Postives = 244/412 (59.22%), Query Frame = 3 
Query: 1620 TVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEM--LIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            T + SV++   FLV +I+Y  ++  ++    + ++   +  I +++ S+++LI+IL++  VY+ LA  LT  E + TQ++Y+D+ T K+++ +F+N YS  FY  F        PG +K +   +   C  GGCL  L+ QL  IM+G+Q+I++  E+ +P + + ++K KL             ++V  E  R  +D  L   E   +F EYLEM  ++QFGFIT+F+ AFPLAPL AL NN +E+R DA KF+  Y+RPVA+R +DIG W NIL  +  ++V  NA LIAFT+ F+ +LLY  +Y+   +L+G+ +FTLSY      A    E   RY D+R      ++G  TL   YW++LA ++ F+  FE+VV+ I ++I   +P+  E +  ++ +E  ++++ L
Sbjct:    9 TTVLSVVMI--FLVTVIMYRGIVSVVMYKTGNAVLMTQAANIANISSSMVNLILILVMGQVYSSLAEQLTKWEMHRTQTQYEDAFTFKVFVFQFVNFYSSPFYVAFFKGRFVGYPGHYKKLLGTRNEDCGPGGCLIELAQQLIIIMVGKQVINNIQEFVFPKIKAWLQKRKLAALRG--------SHVAPESSRWEEDYELIPCEG--LFEEYLEMGPVLQFGFITIFVAAFPLAPLFALLNNWVELRLDAQKFVCEYRRPVAERAQDIGVWFNILDALVNISVIINAFLIAFTSNFLPKLLY--QYTYDRNLRGYINFTLSYAPDENIA----EANLRYKDYRD-----QDGKHTL--FYWKLLAIRLGFIIAFEHVVFFISRMIDWLVPDVPESLEIKMKRERYLAKQAL 395
[Close]
BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO48050 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU9])

HSP 1 Score: 346.665 bits (888), Expect = 1.172e-105
Identity = 281/890 (31.57%), Postives = 436/890 (48.99%), Query Frame = 3 
Query:  267 AYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKY--EQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHAS----SDIIVNEIKEGGNITMCPLLCNSKQCKFWKLS-DVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFM-----FFKFSTVL----FSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFI-LPLIQPIPG--FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEF----ASSTNET---------------YCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKE 2822
            A QK  +N    K R  + + L K GLE E   EEG        DN+    K  F+K+   W+ L   AE + ++ PI      IK   E+ LS              F  S  SR      P       +   P  +Q  F+   R +I N  L+                  H K+T  S  E    T      E  CS+     +  D+G+                    LI +  + +AY LH      +      ++R KL + W       + QP D+I+ YFG +I  YF+WLGFY   L   ++ G+ + ++ I  ++       I N+  E     MCPL C+ KQC +W L  +  Y  +V    DN + ++ A  MSIWA++FLE WKR Q  LA+ W++   ++Q E  +PEF+  +T  + DK ++     W   VP +     + K + V+    F + L L+ +VG+++Y   +Y  LM +P P V + + +  S+T +I++LI I LL  VY KLA +LT  EN  T++++ DS T K+YL +F+NNY+ +FY  F  L L+   PG   +   + +  GC +GGCL  L +QL  IM+G+Q+I + TE + P L   +K +K+R+  K  +          EI R   D  L  L    +F+EYLE+++QFGF+TMF+ AFPLAPL AL N + E+R DA  F+  ++RP  +R +DIG W++I+  +A ++V  NA +IAFT+ FI RL+Y   YSP G L+G+ + +LSY    ++    A    E                YCRY  + H P      P  ++  YW ++AA++ FV+ F+ +VY + K ++  +P++   +   I ++
Sbjct:   10 AEQKETENSHADK-RRVYEENLKKAGLELE--HEEG--------DNKK--RKTHFVKIHTPWDVLAATAEEMMMKSPIRDSDIEIKSWSEKHLSEE------------FVTSIRSRD-----PLKIHDSCI--TPPKKQ--FVAYFRKVINNPRLQKKQFFVG----------YHDKNTFFSAAERSRMT------ERICSQQRFGEERFDQGIK------------------RLIHQGTYTAAYPLHSGPEEVSRKGHPSNERQKLRRDWARFGRWFKYQPYDAIKDYFGTEIGLYFAWLGFYAAMLVPAAIFGVAVFIYGIAQSTIFPPVKDICNKAYEA-EFYMCPL-CD-KQCPYWSLVVNCPYAIWV-HAFDNDSTVVFAIFMSIWATVFLEFWKRRQAVLAYEWHMMHYEDQEEQPRPEFIVTVTTLKKDKASQ-----WGGMVPHVPKLQQYRKLAGVVSLVAFMIALVLSAVVGVVIYRASVYGSLMAYPDPQVRKQAKMTTSITAAILNLICINLLKFVYEKLAMFLTEWENPRTETDFKDSFTYKMYLFQFVNNYASIFYIAFFKLNLVIGTPGNYRRFAGEYRLDGCSSGGCLMDLCIQLVIIMVGQQIIGNITEIAIPGL---LKWWKMRQAQKEAFE---------EIPRWEVDYKLNTLPEHHLFWEYLEVVLQFGFVTMFVAAFPLAPLFALVNAVFELRVDAINFVCQFRRPTPRRAQDIGAWMSIMQGLANISVLVNAFVIAFTSDFIPRLVYTTAYSPDGTLRGYLNNSLSYFNVKDYDRMGAIGAREKPGDNYAYTVLNYTREYCRYPGY-HEP----EFPYEVSKQYWHVIAARLAFVFAFQYIVYAVTKFVAWLVPDRPRHLELRIKRQ 805
[Close]
BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO49855 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REV0])

HSP 1 Score: 325.865 bits (834), Expect = 5.409e-98
Identity = 223/648 (34.41%), Postives = 350/648 (54.01%), Query Frame = 3 
Query:  945 NMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLY------KCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNI--LHASSDIIVNEIKEGGNIT--MCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAF---ITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
             + +  L+ E VF++ Y LH    V   L +       +Y      + WG      + QPLD IR YFGEKI  YF+WLG YT WL  PS LGL++ ++ +  +++S +    E+ +    T  MCPL      C++W L        +  + DN + +  A  +S W+  FLE WKR++  LA+HW+V + + + E  +P F A    + +N      E   P  +R  P +F   + V   V L L F+VG+I+Y++++Y  L  +PS     +     +     +++I+IL     Y ++A  LT  E + TQ+EY+DS+T K+++ +F N YS +FY  F    +   PG ++ +  L+   C  GGCL  L+ QL  IM+G+Q+I++  E + PL+   IK            R K  T+ +    R   D  L  +E++ +F EYLEM++QFGFIT+F+ AFPLAP  AL NN+ EIR D+ KF+   +RP+A R +DIG W NIL  VA +AV SNA LIAFT+ F+ +LLY    S    L+G++++TL++        +T    CRY +FR        G  T+   YW +LA ++ FV +FE+VV+ +M++I   +P+    +   I +E  ++++ L
Sbjct:  155 EIGIERLVEEGVFKAGYPLH----VNCYLNQQGYSPFLIYVSQVLKEYWGRWGKWLKYQPLDHIRDYFGEKIGIYFAWLGQYTAWLIMPSFLGLLVFLYGVATINSSDNKPALEVCDNPPWTFRMCPLCDEELGCQYWDLHISCKSGKIAYLFDNASTVFFAVFVSFWSCFFLEYWKRKEVTLAYHWDVLEYEEEAERPRPTFAALAPTVERNPVTGILEPHFPDEKRK-PRLFSGIAIVFTMVSLVLVFMVGVIVYKLLVYRPLARNPSTRAYALQIANSTGAFVNLTIIMILSRV--YERVALALTHWEMHRTQTEYEDSLTFKVFVFQFANFYSSIFYVAFFKGKLVGYPGHYRRLFGLRQEECSPGGCLMELAQQLVIIMVGKQMINNVQEIAIPLVKQWIK------------RKKRGTSKDEIKPRWEQDFEL--VENEGLFQEYLEMILQFGFITIFVAAFPLAPFFALANNIFEIRIDSDKFVCEVRRPIADRAQDIGIWFNILDSVAKIAVISNAFLIAFTSTFLPKLLYRYAVSENFSLEGYTNYTLAWA-----PRNTTLKPCRYQEFRD-----PEGHFTV--FYWHLLALRLGFVIMFEHVVFFVMRLIDMMVPDIPTELEIIIKREAYLAKQAL 769
[Close]
BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO48049 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU8])

HSP 1 Score: 293.508 bits (750), Expect = 1.474e-86
Identity = 217/666 (32.58%), Postives = 356/666 (53.45%), Query Frame = 3 
Query:  945 NMSLHNLISEQVFESAYCLHESFIVQNSLKRDES---DRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEI---KEGGNITMCPLLCNSKQCKFWKLSDVYYKF-FVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAF---ITQNQTDKGNESSVPFWRRTVPFMFFKFST----VLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILP-LIQPIPGF--KAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSP----TGDLKGFSDFTLSYLKSSEFASSTNE-----------TYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
             + L  L+ E  +   Y LH+     + +K  E+   DR +L + W       + QP D+I+SYFG +I  YF+WLGFYT  L   ++ GLV+ ++ I+ A+    V ++   K  G   MCPL C+ KQC +W L+     + +V    DN   + +A   SIWA+LFLE+WKR Q  LA  W+V D + + E  +PEF A    + +N      E  VP  +RT   ++ ++ T    ++   +L +A +VG+++Y   ++A L       +   +  + S+T +II+LI I +L  VY+ LA  LT  EN  T+++Y+DS T K+YL +F+N Y+ +FY  F    L+   PG   +     +  GC   GC   L +QL  IM+G+Q+I + TE + P L   +K+ K  K              + ++ +   D  L  L    +F+EYLE+++Q+GF+TMF+ AFPLAPL +L N+++EIR DA  F+  ++RP A R +DIG W  IL  +  L+V  NA +++FT+ F+ RLLY LKY+P     G L+G+ + +L+  + +     T             T CRY  +  +       P      YW ++A ++ FV++F+  VY   + ++  IP++ + +  +I +E  ++++L+
Sbjct:  115 GLGLKQLLYEGAYIGNYPLHDG---DDEVKEGETISNDRQRLRRDWASFGRCFKYQPYDAIKSYFGTEIGLYFAWLGFYTGMLVPLAIAGLVVFIYGIVDATMSPPVRDVCDSKNEGRWIMCPL-CD-KQCSYWDLAKTTCAYAYVTHFFDNSLTVALAVVSSIWATLFLELWKRRQASLANKWHVSDFEEE-ETIRPEFAATAPRLKKNPVTGLQEPYVP--KRT---LYQRYGTTGSIIVMMCLLVIAAVVGVVIYRAAVFASLSGSEILTIRMRARTVTSITAAIINLICINILKFVYSWLAVKLTNWENPRTRTDYEDSFTYKMYLFQFVNTYASIFYIAFFKSGLVIGTPGRYKRIAGKYRLDGCSEQGCFLELCIQLIIIMVGQQIIGNITEIAIPALMEWMKRRKEPK--------------DKQLPQYQQDFDLNSLGEHNMFWEYLEVVLQYGFVTMFVAAFPLAPLFSLLNSIVEIRVDAINFVRQFRRPDAARAEDIGAWSRILEGLTKLSVLVNAFVLSFTSDFVPRLLYRLKYAPDRDSGGSLEGYLNNSLAVFEVAYLEPGTEPENPLQSINYTVTTCRYPGYHSN-----TAPFKFNKQYWHVIAGRLAFVFVFQYTVYAFTQFLAWLIPDRTKTLDLKIKREQYLAKQLI 750
[Close]
BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO48048 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU7])

HSP 1 Score: 290.812 bits (743), Expect = 1.170e-84
Identity = 213/667 (31.93%), Postives = 355/667 (53.22%), Query Frame = 3 
Query:  966 ISEQVFESAYC----LHES---FIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGN-ITMCPLLCNSKQCKFWKLSDVYYKFF-VIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAF---ITQNQTDKGNESSVPFWRRTVPFMFFKFSTVL-FSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXX-------XXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILP-LIQPIPGF--KAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD---LKGFSDFTLSYLKSS---EFASST-----------NETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            + + V+E AYC    LH+     I ++S   +  DR +L K W   + I + QPLD+++ Y+G  IA YF+WLGFYT  L   +++GL++ ++ I  +++   V +  +  N   MCPL C+ + C +W L      +  V    DN   + +A   S+WA+LFLE WKR Q  LA+ W+V + + + E  +PEF A    + +N      E  +P  RRT+   +    +V+ F ++L +A ++G+++Y   ++A L  +    +     +I   +  I S+   L+       L + Y +LA WLT  EN  T+++Y+DS T K+YL +F+N Y+ +FY  F    ++   PG   +     +  GC   GC   L VQ+  IM+G+Q+I + TE + P + + IK+ K  K              N ++ +   D  L   E   +F+EYLE+++Q+GF+TMFI AFPLAPL +L N+++EIR DA  F++ ++RP     +DIG W  IL  +  L+V  NA +++FT+ FI +L+Y LKY+P G    L+G+ + +LS +  +   E+   T            ET+CRY  +  +       P      YW ++AA++ FV++F+  VY I   I+  +P+Q   +     +E  +++K+L
Sbjct:  189 LKQLVYEGAYCANYPLHDGDDDVIGESSYPSN--DRQRLKKDWSSMKRIFKYQPLDTVKGYYGTAIALYFAWLGFYTAMLIPLAIVGLLVFIYGIGSSATSPTVRDACDTNNKFYMCPL-CD-RTCSYWDLVSTTCMYARVTHFFDNDGTVFLAIFTSVWATLFLEFWKRRQAVLAYEWHVANFEEEEEQIRPEFAATAPTLKKNIITGKLEPHIP--RRTLYQRYGAIGSVVAFMILLVIAAVIGVVVYRAAVFAALSGNSDSTIRARYAMIAIGSRIITSMTAALINLLCINILKLFYNRLAVWLTNWENPRTKTDYEDSFTYKMYLFQFVNTYASIFYIAFFKSEIVVGTPGRYKRIAGKYRLEGCSAQGCFLELCVQMLIIMVGQQIIGNITEVAIPAIMTWIKERKEPK--------------NKQLPQFEQDYNLQPQEEHNLFWEYLEIVLQYGFVTMFIAAFPLAPLFSLLNSIVEIRVDAINFVSQFRRPDTMIAEDIGAWYRILETLTRLSVLINAFVLSFTSEFIPKLVYKLKYAPEGSEGTLEGYLNNSLSAINVTVMEEWEPGTAPLNPTKNLNYTETFCRYKGYHDNTY-----PFKFNKQYWHVIAARLAFVFVFQYTVYAITSFIAWAVPDQPRSLELRSKREEHLTKKIL 830
[Close]
BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO49854 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REU8])

HSP 1 Score: 278.1 bits (710), Expect = 2.365e-81
Identity = 218/649 (33.59%), Postives = 341/649 (52.54%), Query Frame = 3 
Query:  948 MSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYF-----GEKIAFYFSWLGFYTYWLFFPSLLGLVIAV--FNILHASSDIIVNEIKEGGNIT--MCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAF---ITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHP---SPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            + +  L+ E  + +AY LH      + +K +    +K Y  W       + QPLD IR  +     G KIA YF+WLG YT WL  PS++GL++ +  F  ++  +++   E+ +    T  MCP  C    C  W L     +     + DN   +  +  +S WA LFLE WKR++  +   W+V + +++ E  +P F A    + +N      E   P  +R+ P +    + +   V L + F+VG+I     +Y LL++HP   +P +   +N   S TG++++LI+I++L+ VY KLA  L   E + TQ+EY+D++T+K+++ +F N YS +FY  F        PG +  +  L+   C  GGCL  L+ QLA IMIG+Q+I +  E   P L   +K       N+ +  SK+   +     R   D  L D E   +F EYLEM+IQ+GFIT+F+ AFPLAP  AL NN+ EIR DA KF+   +R  A R +DIG W  IL  +  LAV SNA LIAFT+ F+ +LLY    SP   L+G+ +++L++        +T    CRY  FR      ++G    T  +W +L  +++FV LFE+ V+ I  +I   +P+    +   I +E  ++ + L
Sbjct:   71 IGISRLVDEGTYSAAYPLHVGPHGPDEMKLNMRQVLKEY--WARWGAWYKYQPLDHIRQAYEREGGGLKIAIYFAWLGQYTAWLIMPSVVGLIVFIYSFATINGPNNMPALEMCDHPAWTYPMCPN-CEVG-CSVWDLKKSCSRAKHAYLFDNPMTVAYSIFVSFWAVLFLEFWKRKEVTIGHAWDVLEFESEEERPRPTFAALAPAVERNPITGLLEPYFPDEKRS-PRVLSGIAIICGMVSLVMLFMVGVI-----VYKLLVIHPLYKNPNLQPYANQFASGTGAVLNLIIIMILSRVYEKLALLLNHWEMHRTQTEYEDNLTLKVFIFQFTNFYSSIFYIAFFKGKFVGYPGNYGTIFGLRNEECSPGGCLIELAQQLAVIMIGKQVIGNIQEVFIPELKKYLK-------NRKRQNSKDEDEIKP---RWEADYELLDNEG--LFQEYLEMVIQYGFITLFVAAFPLAPFFALANNVFEIRIDADKFVNDLRRSTADRAQDIGVWFTILDSITKLAVISNAFLIAFTSEFLPKLLYAGVVSPNQSLEGYLNYSLAWA-----PPNTTSQPCRYRGFRD-----EDG--NFTRFFWHLLTMRLVFVILFEHFVFGISTLIDVAVPDIPRALEDTIKREKYVATQAL 685
[Close]
BLAST of Anoctamin vs. Ensembl Medaka
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:101164640])

HSP 1 Score: 359.762 bits (922), Expect = 2.253e-109
Identity = 285/925 (30.81%), Postives = 443/925 (47.89%), Query Frame = 3 
Query:  204 KTTTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHES-FIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNIL-----HASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQ--KPEFVAFITQNQTDKGNESSVPFWRRT--VPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL--MMHPSP----------LVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-----FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--LKGFSDFTLSYLKSSE---------------FASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            +  + + +FF DG+R+IDFVL+Y    D ER ++ R  F   L+K GLE EI+D+           +  D  K  F+K+ A WE L  YA++L+I+ P     ++I     +        F +               FT PF  SK   F I  +R  FF+ + R+ IV YIL                                          S CS       E D+                   +  L++   + +A+ LH+S +  ++     +SDR  LYK W    +  + QPL+ IR Y+GEKI  YF+WLGFYT  LFF +++G +  V+ +L       S +I  +EI  GGNI MCPL C+ K+C FWKL+      +   + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+       + ++  +   P+   T     +    +TVL  + L +A ++G+I Y + +YA    +M  SP          +  Q++  + +   + + ++++ L+   Y ++A W+T +E  +T  EY++ +T+K++L +F+N YS  FY  F        PG     F   S L+   C  GGCL  L+ QL  +M G+Q+  +  E   P L +     K R   +  Y             R   D  L       +FYEYLEM+IQFGFIT+F+ +FPLAPLLALFNN++EIR DA K  T ++RPVA +   IG W  IL+ +A L+V +NA ++AFT+  I RL+Y+  Y P G+  +KG+ + +LS    SE               F SS   T CRY D+R+ P        + T  +W ILAAK+ F+ + E+VV+ +   ++  IP+    +   + +E  + ++ L
Sbjct:    6 QQQSKDSVFFRDGVRRIDFVLSYVDDKDGERKQERRRVFEANLVKVGLELEIEDK-----------SESDDRKTYFVKIHAPWEVLATYADVLKIKVPF--KANDIPDNSEMPMNWLSTPFRLPE----PIMQPEPDFFTAPFDKSKSDFFLI-EDRDKFFLPSTRNRIVYYIL------------------------------------------SRCSYIRDECGERDKK-----------------GIKRLLNNSTYTAAFPLHDSRYWTKSKDVNCDSDRYNLYKYWAGFFSFFKEQPLNLIRKYYGEKIGLYFAWLGFYTEMLFFAAVVGTLCFVYGVLTYDDNEWSKEICSDEI--GGNIVMCPL-CD-KKCGFWKLNTTCNSSWQSHLFDNVGTVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCNSRKLNRITQEMEPYLPITSKCARICLSGATVLLWISLIIACIIGVIAYRLAVYAAFASIMKDSPTSNLEVVGPYITPQLATSVTASCINFVIIMILNLM---YERVAVWITDMEIPKTHLEYENKLTVKMFLFQFVNYYSSCFYVAFFKGKFVGYPGDYAYMFGKWSKLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALVPWLMNWWASRKARSYPESLYS------------RWEQDHDLQGFGQLGLFYEYLEMVIQFGFITLFVASFPLAPLLALFNNIIEIRVDAWKLTTQFRRPVAAKAHCIGAWEEILNGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYQPEGEMNMKGYINNSLSVFNISEIPLPNRPEDGENPLWFNSSI--TTCRYRDYRNPPG--HENQYSHTMQFWHILAAKLAFIIIMEHVVFLVKYFVAWMIPDVPSDVKARVKRERYLVQEYL 830
[Close]
BLAST of Anoctamin vs. Ensembl Medaka
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:101164640])

HSP 1 Score: 358.992 bits (920), Expect = 9.026e-109
Identity = 285/925 (30.81%), Postives = 443/925 (47.89%), Query Frame = 3 
Query:  204 KTTTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHES-FIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNIL-----HASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQ--KPEFVAFITQNQTDKGNESSVPFWRRT--VPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL--MMHPSP----------LVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-----FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--LKGFSDFTLSYLKSSE---------------FASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLL 2846
            +  + + +FF DG+R+IDFVL+Y    D ER ++ R  F   L+K GLE EI+D+           +  D  K  F+K+ A WE L  YA++L+I+ P     ++I     +        F +               FT PF  SK   F I  +R  FF+ + R+ IV YIL                                          S CS       E D+                   +  L++   + +A+ LH+S +  ++     +SDR  LYK W    +  + QPL+ IR Y+GEKI  YF+WLGFYT  LFF +++G +  V+ +L       S +I  +EI  GGNI MCPL C+ K+C FWKL+      +   + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+       + ++  +   P+   T     +    +TVL  + L +A ++G+I Y + +YA    +M  SP          +  Q++  + +   + + ++++ L+   Y ++A W+T +E  +T  EY++ +T+K++L +F+N YS  FY  F        PG     F   S L+   C  GGCL  L+ QL  +M G+Q+  +  E   P L +     K R   +  Y             R   D  L       +FYEYLEM+IQFGFIT+F+ +FPLAPLLALFNN++EIR DA K  T ++RPVA +   IG W  IL+ +A L+V +NA ++AFT+  I RL+Y+  Y P G+  +KG+ + +LS    SE               F SS   T CRY D+R+ P        + T  +W ILAAK+ F+ + E+VV+ +   ++  IP+    +   + +E  + ++ L
Sbjct:   50 QQQSKDSVFFRDGVRRIDFVLSYVDDKDGERKQERRRVFEANLVKVGLELEIEDK-----------SESDDRKTYFVKIHAPWEVLATYADVLKIKVPF--KANDIPDNSEMPMNWLSTPFRLPEPIM----QPEPDFFTAPFDKSKSDFFLI-EDRDKFFLPSTRNRIVYYIL------------------------------------------SRCSYIRDECGERDKK-----------------GIKRLLNNSTYTAAFPLHDSRYWTKSKDVNCDSDRYNLYKYWAGFFSFFKEQPLNLIRKYYGEKIGLYFAWLGFYTEMLFFAAVVGTLCFVYGVLTYDDNEWSKEICSDEI--GGNIVMCPL-CD-KKCGFWKLNTTCNSSWQSHLFDNVGTVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCNSRKLNRITQEMEPYLPITSKCARICLSGATVLLWISLIIACIIGVIAYRLAVYAAFASIMKDSPTSNLEVVGPYITPQLATSVTASCINFVIIMILNLM---YERVAVWITDMEIPKTHLEYENKLTVKMFLFQFVNYYSSCFYVAFFKGKFVGYPGDYAYMFGKWSKLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALVPWLMNWWASRKARSYPESLYS------------RWEQDHDLQGFGQLGLFYEYLEMVIQFGFITLFVASFPLAPLLALFNNIIEIRVDAWKLTTQFRRPVAAKAHCIGAWEEILNGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYQPEGEMNMKGYINNSLSVFNISEIPLPNRPEDGENPLWFNSSI--TTCRYRDYRNPPG--HENQYSHTMQFWHILAAKLAFIIIMEHVVFLVKYFVAWMIPDVPSDVKARVKRERYLVQEYL 874
[Close]
BLAST of Anoctamin vs. Ensembl Medaka
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:101164640])

HSP 1 Score: 359.762 bits (922), Expect = 1.827e-108
Identity = 288/925 (31.14%), Postives = 442/925 (47.78%), Query Frame = 3 
Query:  183 KDNERIPKTT-TNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHES-FIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNIL-----HASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQ--KPEFVAFITQNQTDKGNESSVPFWRRT--VPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL--MMHPSP----------LVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-----FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--LKGFSDFTLSYLKSSE---------------FASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKE 2822
            K   RI K   + + +FF DG+R+IDFVL+Y    D ER ++ R  F   L+K GLE EI+D+           +  D  K  F+K+ A WE L  YA++L+I+ P     ++I     +        F +               FT PF  SK   F I  +R  FF+ + R+ IV YIL                                          S CS       E D+                   +  L++   + +A+ LH+S +  ++     +SDR  LYK W    +  + QPL+ IR Y+GEKI  YF+WLGFYT  LFF +++G +  V+ +L       S +I  +EI  GGNI MCPL C+ K+C FWKL+      +   + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+       + ++  +   P+   T     +    +TVL  + L +A ++G+I Y + +YA    +M  SP          +  Q++  + +   + + ++++ L+   Y ++A W+T +E  +T  EY++ +T+K++L +F+N YS  FY  F        PG     F   S L+   C  GGCL  L+ QL  +M G+Q+  +  E   P L +     K R   +  Y             R   D  L       +FYEYLEM+IQFGFIT+F+ +FPLAPLLALFNN++EIR DA K  T ++RPVA +   IG W  IL+ +A L+V +NA ++AFT+  I RL+Y+  Y P G+  +KG+ + +LS    SE               F SS   T CRY D+R+ P        + T  +W ILAAK+ F+ + E+VV+ +   ++  IP+    +   + +E
Sbjct:  102 KYRSRIQKQQQSKDSVFFRDGVRRIDFVLSYVDDKDGERKQERRRVFEANLVKVGLELEIEDK-----------SESDDRKTYFVKIHAPWEVLATYADVLKIKVPF--KANDIPDNSEMPMNWLSTPFRLPEPIM----QPEPDFFTAPFDKSKSDFFLI-EDRDKFFLPSTRNRIVYYIL------------------------------------------SRCSYIRDECGERDKK-----------------GIKRLLNNSTYTAAFPLHDSRYWTKSKDVNCDSDRYNLYKYWAGFFSFFKEQPLNLIRKYYGEKIGLYFAWLGFYTEMLFFAAVVGTLCFVYGVLTYDDNEWSKEICSDEI--GGNIVMCPL-CD-KKCGFWKLNTTCNSSWQSHLFDNVGTVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCNSRKLNRITQEMEPYLPITSKCARICLSGATVLLWISLIIACIIGVIAYRLAVYAAFASIMKDSPTSNLEVVGPYITPQLATSVTASCINFVIIMILNLM---YERVAVWITDMEIPKTHLEYENKLTVKMFLFQFVNYYSSCFYVAFFKGKFVGYPGDYAYMFGKWSKLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALVPWLMNWWASRKARSYPESLYS------------RWEQDHDLQGFGQLGLFYEYLEMVIQFGFITLFVASFPLAPLLALFNNIIEIRVDAWKLTTQFRRPVAAKAHCIGAWEEILNGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYQPEGEMNMKGYINNSLSVFNISEIPLPNRPEDGENPLWFNSSI--TTCRYRDYRNPPG--HENQYSHTMQFWHILAAKLAFIIIMEHVVFLVKYFVAWMIPDVPSDVKARVKRE 926
[Close]
BLAST of Anoctamin vs. Ensembl Medaka
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:101164640])

HSP 1 Score: 360.147 bits (923), Expect = 3.473e-108
Identity = 284/917 (30.97%), Postives = 439/917 (47.87%), Query Frame = 3 
Query:  204 KTTTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHES-FIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNIL-----HASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQ--KPEFVAFITQNQTDKGNESSVPFWRRT--VPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL--MMHPSP----------LVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-----FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--LKGFSDFTLSYLKSSE---------------FASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKE 2822
            +  + + +FF DG+R+IDFVL+Y    D ER ++ R  F   L+K GLE EI+D+           +  D  K  F+K+ A WE L  YA++L+I+ P     ++I     +        F +               FT PF  SK   F I  +R  FF+ + R+ IV YIL                                          S CS       E D+                   +  L++   + +A+ LH+S +  ++     +SDR  LYK W    +  + QPL+ IR Y+GEKI  YF+WLGFYT  LFF +++G +  V+ +L       S +I  +EI  GGNI MCPL C+ K+C FWKL+      +   + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+       + ++  +   P+   T     +    +TVL  + L +A ++G+I Y + +YA    +M  SP          +  Q++  + +   + + ++++ L+   Y ++A W+T +E  +T  EY++ +T+K++L +F+N YS  FY  F        PG     F   S L+   C  GGCL  L+ QL  +M G+Q+  +  E   P L +     K R   +  Y             R   D  L       +FYEYLEM+IQFGFIT+F+ +FPLAPLLALFNN++EIR DA K  T ++RPVA +   IG W  IL+ +A L+V +NA ++AFT+  I RL+Y+  Y P G+  +KG+ + +LS    SE               F SS   T CRY D+R+ P        + T  +W ILAAK+ F+ + E+VV+ +   ++  IP+    +   + +E
Sbjct:  161 QQQSKDSVFFRDGVRRIDFVLSYVDDKDGERKQERRRVFEANLVKVGLELEIEDK-----------SESDDRKTYFVKIHAPWEVLATYADVLKIKVPF--KANDIPDNSEMPMNWLSTPFRLPEPIM----QPEPDFFTAPFDKSKSDFFLI-EDRDKFFLPSTRNRIVYYIL------------------------------------------SRCSYIRDECGERDK-----------------KGIKRLLNNSTYTAAFPLHDSRYWTKSKDVNCDSDRYNLYKYWAGFFSFFKEQPLNLIRKYYGEKIGLYFAWLGFYTEMLFFAAVVGTLCFVYGVLTYDDNEWSKEICSDEI--GGNIVMCPL-CD-KKCGFWKLNTTCNSSWQSHLFDNVGTVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCNSRKLNRITQEMEPYLPITSKCARICLSGATVLLWISLIIACIIGVIAYRLAVYAAFASIMKDSPTSNLEVVGPYITPQLATSVTASCINFVIIMILNLM---YERVAVWITDMEIPKTHLEYENKLTVKMFLFQFVNYYSSCFYVAFFKGKFVGYPGDYAYMFGKWSKLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALVPWLMNWWASRKARSYPESLYS------------RWEQDHDLQGFGQLGLFYEYLEMVIQFGFITLFVASFPLAPLLALFNNIIEIRVDAWKLTTQFRRPVAAKAHCIGAWEEILNGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYQPEGEMNMKGYINNSLSVFNISEIPLPNRPEDGENPLWFNSSI--TTCRYRDYRNPPG--HENQYSHTMQFWHILAAKLAFIIIMEHVVFLVKYFVAWMIPDVPSDVKARVKRE 977
[Close]
BLAST of Anoctamin vs. Ensembl Medaka
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:101164640])

HSP 1 Score: 360.147 bits (923), Expect = 4.928e-108
Identity = 288/925 (31.14%), Postives = 442/925 (47.78%), Query Frame = 3 
Query:  183 KDNERIPKTT-TNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHES-FIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNIL-----HASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQ--KPEFVAFITQNQTDKGNESSVPFWRRT--VPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALL--MMHPSP----------LVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-----FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGD--LKGFSDFTLSYLKSSE---------------FASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKE 2822
            K   RI K   + + +FF DG+R+IDFVL+Y    D ER ++ R  F   L+K GLE EI+D+           +  D  K  F+K+ A WE L  YA++L+I+ P     ++I     +        F +               FT PF  SK   F I  +R  FF+ + R+ IV YIL                                          S CS       E D+                   +  L++   + +A+ LH+S +  ++     +SDR  LYK W    +  + QPL+ IR Y+GEKI  YF+WLGFYT  LFF +++G +  V+ +L       S +I  +EI  GGNI MCPL C+ K+C FWKL+      +   + DN   +  A  M IW +LFLE WKR Q RL + W++ D + + +    +PE+       + ++  +   P+   T     +    +TVL  + L +A ++G+I Y + +YA    +M  SP          +  Q++  + +   + + ++++ L+   Y ++A W+T +E  +T  EY++ +T+K++L +F+N YS  FY  F        PG     F   S L+   C  GGCL  L+ QL  +M G+Q+  +  E   P L +     K R   +  Y             R   D  L       +FYEYLEM+IQFGFIT+F+ +FPLAPLLALFNN++EIR DA K  T ++RPVA +   IG W  IL+ +A L+V +NA ++AFT+  I RL+Y+  Y P G+  +KG+ + +LS    SE               F SS   T CRY D+R+ P        + T  +W ILAAK+ F+ + E+VV+ +   ++  IP+    +   + +E
Sbjct:  167 KYRSRIQKQQQSKDSVFFRDGVRRIDFVLSYVDDKDGERKQERRRVFEANLVKVGLELEIEDK-----------SESDDRKTYFVKIHAPWEVLATYADVLKIKVPF--KANDIPDNSEMPMNWLSTPFRLPEPIM----QPEPDFFTAPFDKSKSDFFLI-EDRDKFFLPSTRNRIVYYIL------------------------------------------SRCSYIRDECGERDK-----------------KGIKRLLNNSTYTAAFPLHDSRYWTKSKDVNCDSDRYNLYKYWAGFFSFFKEQPLNLIRKYYGEKIGLYFAWLGFYTEMLFFAAVVGTLCFVYGVLTYDDNEWSKEICSDEI--GGNIVMCPL-CD-KKCGFWKLNTTCNSSWQSHLFDNVGTVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCNSRKLNRITQEMEPYLPITSKCARICLSGATVLLWISLIIACIIGVIAYRLAVYAAFASIMKDSPTSNLEVVGPYITPQLATSVTASCINFVIIMILNLM---YERVAVWITDMEIPKTHLEYENKLTVKMFLFQFVNYYSSCFYVAFFKGKFVGYPGDYAYMFGKWSKLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALVPWLMNWWASRKARSYPESLYS------------RWEQDHDLQGFGQLGLFYEYLEMVIQFGFITLFVASFPLAPLLALFNNIIEIRVDAWKLTTQFRRPVAAKAHCIGAWEEILNGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYQPEGEMNMKGYINNSLSVFNISEIPLPNRPEDGENPLWFNSSI--TTCRYRDYRNPPG--HENQYSHTMQFWHILAAKLAFIIIMEHVVFLVKYFVAWMIPDVPSDVKARVKRE 991
[Close]
BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000033730.1 (SMESG000033730.1)

HSP 1 Score: 1740.7 bits (4507), Expect = 0.000e+0
Identity = 887/898 (98.78%), Postives = 894/898 (99.55%), Query Frame = 3 
Query:  159 MYDNRFSTKDNERIPKTTTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK 2852
            MYDNRFSTKDNERIPKTT NNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDN+DDT+KIVFIKLFAKWETLCHYAELLRIRKPILHPPS+IKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANI+HPKSTPSSIT+MEMRTFSTINSESECSKSHSNNDETDEGLTEI HLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRV LYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVI VFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTM+LMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMSNVIISVTGSIISLIVILLLTMVYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIPAFPLAPLLALFNNLLEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFR+HPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK
Sbjct:    1 MYDNRFSTKDNERIPKTTINNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNQDDTKKIVFIKLFAKWETLCHYAELLRIRKPILHPPSSIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANILHPKSTPSSITDMEMRTFSTINSESECSKSHSNNDETDEGLTEIQHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVNLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVITVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMVLMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMSNVIISVTGSIISLIVILLLTMVYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIPAFPLAPLLALFNNLLEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRYHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK 898
[Close]
BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000033730.1 (SMESG000033730.1)

HSP 1 Score: 1143.64 bits (2957), Expect = 0.000e+0
Identity = 576/587 (98.13%), Postives = 583/587 (99.32%), Query Frame = 3 
Query:  159 MYDNRFSTKDNERIPKTTTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSY 1919
            MYDNRFSTKDNERIPKTT NNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDN+DDT+KIVFIKLFAKWETLCHYAELLRIRKPILHPPS+IKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANI+HPKSTPSSIT+MEMRTFSTINSESECSKSHSNNDETDEGLTEI HLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRV LYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVI VFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTM+LMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMSNVIISVTGSIISLIVILLLTMVYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYS+
Sbjct:    1 MYDNRFSTKDNERIPKTTINNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENFDNQDDTKKIVFIKLFAKWETLCHYAELLRIRKPILHPPSSIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANILHPKSTPSSITDMEMRTFSTINSESECSKSHSNNDETDEGLTEIQHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVNLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVITVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMVLMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMSNVIISVTGSIISLIVILLLTMVYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSF 587

HSP 2 Score: 89.7373 bits (221), Expect = 3.719e-18
Identity = 43/52 (82.69%), Postives = 44/52 (84.62%), Query Frame = 2 
Query: 1934 FHLTTHSTNSRFQGNVRLETNWMSNWRLFVRTFSSVGIYYDRSSIDQSFHRI 2089
             +L     N  FQGNVRLETNWMSNWRLFVRTFSSVGIYYDRSSIDQSFHRI
Sbjct:  576 LYLLEFINNYSFQGNVRLETNWMSNWRLFVRTFSSVGIYYDRSSIDQSFHRI 627
[Close]
BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000033728.1 (SMESG000033728.1)

HSP 1 Score: 760.37 bits (1962), Expect = 0.000e+0
Identity = 422/839 (50.30%), Postives = 574/839 (68.41%), Query Frame = 3 
Query:  216 NNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDE--------EGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNI-LANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNS--LKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGN------ESSVPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRK--------------CNKVKYRSKNITN-----------VNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASS 2606
            NNG+FF DG+R+IDFVL Y+++NDN  N+  R  FLK L+K+GLE EIQD+        E + +  ++  +      IVFIK+FA WETLC YAE+L+IRK +L       + +   F++ F  FD  N++  N        FT P+S SKEYLFDIP +   FF   ERSLIVNYILR  + +   +KC I   +I   +   S   ++EM T +  N+ +E +     N +   G  +       ++K  +  +  LISE VF+SAY LHE  + ++      + ++R  LYK W   RNI R QPLD I+ YFGEK+AFYF+WLG+YTYWL   SLLG++++++NI++ S+DI+V EI +G NITMCPL+C+S+ C+FWKLSD Y +FF+IR+LDN   +LMA  MSIWASLFLEMWKR+Q +LA+HWNV+D++ + EP +PEFVA I +N   K N      E  +PFWRR +P MFF +STVL S+ +ALAFL GIILY++V ++L+ MH S  ++ MS++I + TGS++SL++I+ LT+VY+++A WLT +E++ TQS+YD SVT+KLYLLEFINNYS +FY GFI P  QPIP F++ S +KP GCP GGCL  LS+QLAFIMIG+Q+ISH  EY+ P L S++K+YKL++               ++V+   K+              V  E+IRCY D +L+D   +P+F EYLEMLIQFGFIT+FIPAFPLAPLLAL NNL EIR+DA KF  A +RPVAQRVKDIG W++I+S+VA +AVKSNAILIAF T +I++L+YI+ YS  G L GF+DF+LSY+ SSEF ++
Sbjct:   22 NNGMFFVDGVRKIDFVLVYERINDNRTNQIKRMTFLKSLLKEGLEIEIQDDGCKVYPFKENSYYDNDSVGSPSHRSNIVFIKVFATWETLCRYAEVLKIRKQMLSLGFEYDFNRKTIFQRLFETFDFLNIFNINELKPIPRGFTTPYSKSKEYLFDIPEDNATFFTAAERSLIVNYILRRASYRRISDKCAIEPVDIDVVEDILSRRCDVEMATITDENNVNEMN--FDTNCQAPSG-DKPFAFEDISNKTVDFGIAKLISEGVFDSAYILHERPLNEDDDLENVENNERNLLYKHWVSMRNIFRLQPLDHIKLYFGEKVAFYFAWLGYYTYWLLPISLLGIIVSLYNIVYTSNDIVVKEIYQGTNITMCPLMCSSRGCRFWKLSDAYSRFFLIRLLDNGATVLMAVVMSIWASLFLEMWKRQQVQLAYHWNVHDMEYEDEPARPEFVALIDKNYPKKTNLISGKEEPFIPFWRRRMPVMFFTYSTVLLSIAMALAFLGGIILYKLVSFSLMRMHHSRTISNMSSIITAATGSLLSLVIIMSLTLVYSRVAVWLTDMEHHRTQSQYDSSVTLKLYLLEFINNYSSIFYIGFIQPFTQPIPSFRSSSMIKPRGCPAGGCLLDLSLQLAFIMIGKQIISHIKEYALPRLVSTVKRYKLKQAEEKLINQSDAEMEADRVEVAIKDKATILDPKCIDTWKVEPELIRCYADNILSDPGPRPLFGEYLEMLIQFGFITIFIPAFPLAPLLALTNNLFEIRSDALKFARALRRPVAQRVKDIGIWVSIMSMVATIAVKSNAILIAFATTYIDKLIYIIGYSENGFLNGFTDFSLSYMNSSEFNAT 857
[Close]
BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000033732.1 (SMESG000033732.1)

HSP 1 Score: 696.427 bits (1796), Expect = 0.000e+0
Identity = 406/927 (43.80%), Postives = 584/927 (63.00%), Query Frame = 3 
Query:  204 KTTTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKIRSKFLKILMKQGLEFEIQDEEGNLFSLENF--DNRDD----TEKIVFIKLFAKWETLCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSR-----THTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVKLYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESS------VPFWRRTVPFMFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNK--VKYRSK----------------------NITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEF---ASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK 2852
            K   N G+FFTD +R+IDFVL YQ+L D+E  R  R  F++ L+ +GLE EIQ+  G + ++ +   +N DD    ++ +VF+K+ A W+TLC YAE+++IRK I++   +  Y     F+ +F KF  F+ +   S  ++        +T PFS  K YLFDIP NR  FF   ERSLIVNYIL+    + N    + L+N            E  +     I+S+    +S+SN+  T+E        ++ N    N  +  LISE+VFE+A+ LHE F   N   + E+ RV LYK W    NI R QPLD IR YFGE +AFYF+WLGFYT+WLF  +L G+ + ++N+     DII+ EI E  NITMCP+ C    C+ WKLS  Y +F++IR++DN   +++A  +S+W  LFLEMW+R+QF LAF WNV+DL+ + EP +PE+ A + +N   + N+ S      + FW+ T+P      ST+LFS++L LA L GI + + +I  LL +    L   MS +  +  GS+ISLI I++LT VY+++A WLT LE++ TQS+YD+SVT KLY+LEFINNYS +FY GF  P  +  PG  + S +KP GC TG CL  LS+QL FI++G+Q+IS+   +S P LCSSIK+Y++++ +   +K RS                       N   + +E+  CY D +L+D E +P+F EYLEM+IQFGFIT+FI  FPLAPLLA+ NNL+EIR+DA KF+T Y+RPVAQRVKDIG W++IL+ +A + VKSNA+LIAF T +I+R++YI+ +S   DL GF DF+LS++ ++EF   +S +NET+C Y+ FR+ P D+ N P++ T ++W++LAAK+ FVYLFE  V   +KI    IPN  +     + +E  I+ + +LK
Sbjct:   20 KEKNNKGMFFTDRVRRIDFVLVYQQLLDSEEKRNKRISFIESLIDEGLEIEIQNIGGRIINIADSVNENSDDITCESKNLVFVKIHASWDTLCRYAEIMKIRKSIMNAGVDYNY----IFQSFFEKFVDFDFFRIFSIDNKRLKPIAQGYTYPFSKQKYYLFDIPVNRSEFFTPVERSLIVNYILKRKGYKSNHKPISNLSN------------EKMLVELEPIHSDK---RSNSNDSITNE--------VEENGSNLNFGIAKLISEKVFETAFILHEKF--SNGKYKKENMRVLLYKHWATLTNIFRHQPLDHIRLYFGEMVAFYFAWLGFYTFWLFPIALFGVCVTIYNLATIPRDIIIQEISERNNITMCPVFCIEGSCESWKLSAGYVQFYLIRLIDNGATVILAGVVSVWVFLFLEMWERKQFTLAFRWNVHDLEVEDEPLRPEYAALLEKNYISQFNKISGKEEPFISFWKNTLPIQMLTISTILFSIVLTLACLTGITVTKTIIRNLLRLQ---LTYVMSKLSTAAIGSLISLITIIILTSVYSRVAVWLTDLEHHRTQSQYDNSVTGKLYILEFINNYSSMFYIGFAHPYTKVKPGSDSFSMIKPQGCLTGDCLLDLSMQLIFILVGKQIISNIINFSIPRLCSSIKEYRIKRADSKFIKRRSVHRPTITDYEISEVECSDIYTDCNGVKLQSELKICYQDNILSDPEPRPLFKEYLEMIIQFGFITIFILPFPLAPLLAIINNLMEIRSDAKKFVTVYRRPVAQRVKDIGIWMDILTTIAKIVVKSNALLIAFATSYIDRMIYIIVHSRNFDLGGFVDFSLSFMNTTEFNISSSISNETHCSYIGFRYPPWDVHNEPMSYTPVFWQMLAAKIAFVYLFETFVSLFVKIFLMIIPNIPDEYRIAMKREAAITNEFILK 914
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BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000053932.1 (SMESG000053932.1)

HSP 1 Score: 331.257 bits (848), Expect = 3.398e-99
Identity = 281/892 (31.50%), Postives = 451/892 (50.56%), Query Frame = 3 
Query:  228 FFTDGIRQIDFVLAYQK----LN-DNERNRKI---RSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWETLCHYAELLRIRKPI-LHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSRTHTF-TMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNKCNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTEIHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFI-VQNSL--KRDESDRVK-LYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGLVIAVFNILHASSDIIVNEIKEGGN-ITMCPLLCNSKQCKFWKLSDVYYKFFVIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEPQKPEFVAFITQNQTDKGNESSVPFWRRTVPF--MFFKFSTVLFSVILALAFLVGIILYEIVIYALLMMHPSPLVTQMXXXXXXXXXXXXXXXXXXXXXXXYAKLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQPIPG-FKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLCSSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYLEMLIQFGFITMFIXXXXXXXXXXXXXXXXEIRNDATKFLTAYKRPVAQRVKDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGFSDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILAAKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLL 2849
            +  DGIR+ID+V+ +++    +N D ER R+I   R +F + L+K GL            S E      +   I FIK+   +  +C YAE L  R P+ + PP       +  F +   KF +   +  N        F T  F + +   +    N   FF  T+R  +                  ILA  ++ + T   I                                                +  +I E+++ +AY LHE    V   L  K D  +R + L++ W       + QP+++IR Y+GEKIA YF+WLG YT WLF  SL+G+ + V+ IL   S  I  EI +  N   MCPL    K C++W LSD+ +   +  + D+   +  +  MS+WA  FLE WKR+   L++ W+  D + + E  +PE+VA  T+ + +       P++   +    M      ++   ++ + F++G+I+Y I+I   + +  +PL+   + +  SV+ +I++LI+I+ L +VY KLA+ LT  E + T++E++D +T+K+YL EF+N YS +FY  F        PG +     L+   C  G CLF L+ Q+A IM+G Q+I++  E   P L +   ++K    N V+   K++     E     +D  L   E   +F EYLEM++QFGFIT+F+ AFPLAP  AL NN LEIR DA+K + + +RPVA+R +D+GTW  IL+++  L++ SNA LIAFT+ FI + +Y  KYS    L G+ +FTL++  ++  +       CRY DFR    D+ NG   LT  YW +LA ++ FV +FE++V+ +  +I   IP+  E +  E+ ++  ++++ LL
Sbjct:   36 YLNDGIRRIDYVIVWEQDRIAINVDPERRRRITEYRKRFQEKLLKMGL------------SCEEEIEESEKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPP------HTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAR---------------EILATTVYGRQTKGEI-----------------------------------------------GIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGVMCIVVMFMIVIIFIIGVIIYRILI--AIPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQLSGKDV-----EPKLWSEDYKLLPYEG--LFDEYLEMIVQFGFITIFVAAFPLAPFFALINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVY--KYSHNFLLDGYVNFTLAWAPNNSLSEP-----CRYRDFR----DV-NG--KLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQALL 824
The following BLAST results are available for this feature:
BLAST of Anoctamin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ANO61.923e-10131.23anoctamin 6 [Source:HGNC Symbol;Acc:HGNC:25240][more]
ANO62.525e-10131.23anoctamin 6 [Source:HGNC Symbol;Acc:HGNC:25240][more]
ANO64.024e-10131.23anoctamin 6 [Source:HGNC Symbol;Acc:HGNC:25240][more]
ANO44.481e-9629.55anoctamin 4 [Source:HGNC Symbol;Acc:HGNC:23837][more]
ANO42.176e-9529.55anoctamin 4 [Source:HGNC Symbol;Acc:HGNC:23837][more]
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BLAST of Anoctamin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
anoh-16.061e-3326.10Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286][more]
anoh-17.413e-3326.10Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286][more]
anoh-22.620e-2124.04Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3][more]
anoh-22.674e-2124.04Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3][more]
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BLAST of Anoctamin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
subdued1.478e-11931.45gene:FBgn0038721 transcript:FBtr0334922[more]
subdued1.504e-10835.75gene:FBgn0038721 transcript:FBtr0083806[more]
subdued1.504e-10835.75gene:FBgn0038721 transcript:FBtr0334921[more]
subdued2.315e-10735.75gene:FBgn0038721 transcript:FBtr0083805[more]
subdued4.060e-10735.75gene:FBgn0038721 transcript:FBtr0302492[more]
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BLAST of Anoctamin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ano5b4.109e-10630.91anoctamin 5b [Source:ZFIN;Acc:ZDB-GENE-061215-108][more]
ano117.720e-10035.04anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
ano112.655e-9835.04anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
ano33.558e-9829.89anoctamin 3 [Source:ZFIN;Acc:ZDB-GENE-111031-3][more]
ano114.435e-9835.04anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
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BLAST of Anoctamin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ANO51.902e-9630.65anoctamin 5 [Source:NCBI gene;Acc:100489787][more]
ANO56.576e-9631.20anoctamin 5 [Source:NCBI gene;Acc:100489787][more]
ANO51.719e-9531.00anoctamin 5 [Source:NCBI gene;Acc:100489787][more]
ANO42.449e-9529.72major histocompatibility complex class I-related g... [more]
ANO54.097e-9530.91anoctamin 5 [Source:NCBI gene;Acc:100489787][more]
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BLAST of Anoctamin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ano65.552e-9630.55anoctamin 6 [Source:MGI Symbol;Acc:MGI:2145890][more]
Ano61.685e-9530.55anoctamin 6 [Source:MGI Symbol;Acc:MGI:2145890][more]
Ano15.261e-9533.74anoctamin 1, calcium activated chloride channel [S... [more]
Ano11.800e-9433.74anoctamin 1, calcium activated chloride channel [S... [more]
Ano13.218e-9333.83anoctamin 1, calcium activated chloride channel [S... [more]
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BLAST of Anoctamin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q4KMQ2|ANO6_HUMAN1.213e-10031.23Anoctamin-6 OS=Homo sapiens OX=9606 GN=ANO6 PE=1 S... [more]
sp|Q6P9J9|ANO6_MOUSE3.884e-9530.55Anoctamin-6 OS=Mus musculus OX=10090 GN=Ano6 PE=1 ... [more]
sp|Q32M45|ANO4_HUMAN1.045e-9429.55Anoctamin-4 OS=Homo sapiens OX=9606 GN=ANO4 PE=2 S... [more]
sp|Q8BHY3|ANO1_MOUSE8.192e-9333.83Anoctamin-1 OS=Mus musculus OX=10090 GN=Ano1 PE=1 ... [more]
sp|Q9NQ90|ANO2_HUMAN3.594e-9129.69Anoctamin-2 OS=Homo sapiens OX=9606 GN=ANO2 PE=1 S... [more]
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BLAST of Anoctamin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5K4FF502.378e-17138.69Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A5K4FDS22.481e-16838.30Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A5K4FBC09.292e-16838.21Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A564Y2W13.268e-15736.24Anoctamin OS=Hymenolepis diminuta OX=6216 GN=WMSIL... [more]
A0A564Y4743.970e-15736.24Anoctamin OS=Hymenolepis diminuta OX=6216 GN=WMSIL... [more]
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BLAST of Anoctamin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ano5b3.575e-10731.30anoctamin 5b [Source:ZFIN;Acc:ZDB-GENE-061215-108][more]
ano5a9.040e-10329.74anoctamin 5 [Source:NCBI gene;Acc:103044829][more]
ano5a1.024e-10229.74anoctamin 5 [Source:NCBI gene;Acc:103044829][more]
ano5a2.209e-10229.74anoctamin 5 [Source:NCBI gene;Acc:103044829][more]
ano5a3.170e-10229.74anoctamin 5 [Source:NCBI gene;Acc:103044829][more]
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BLAST of Anoctamin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ano117.970e-9235.69anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
ENSPMAT00000000399.11.181e-8735.46pep scaffold:Pmarinus_7.0:GL477564:2673:43187:-1 g... [more]
ano111.309e-5636.98anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
ano113.411e-5635.44anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
ano111.288e-5435.92anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245][more]
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BLAST of Anoctamin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Anoctamin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO480501.172e-10531.57Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU9][more]
EDO498555.409e-9834.41Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REV0][more]
EDO480491.474e-8632.58Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU8][more]
EDO480481.170e-8431.93Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU7][more]
EDO498542.365e-8133.59Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REU8][more]
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BLAST of Anoctamin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ano5a2.253e-10930.81anoctamin 5 [Source:NCBI gene;Acc:101164640][more]
ano5a9.026e-10930.81anoctamin 5 [Source:NCBI gene;Acc:101164640][more]
ano5a1.827e-10831.14anoctamin 5 [Source:NCBI gene;Acc:101164640][more]
ano5a3.473e-10830.97anoctamin 5 [Source:NCBI gene;Acc:101164640][more]
ano5a4.928e-10831.14anoctamin 5 [Source:NCBI gene;Acc:101164640][more]
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BLAST of Anoctamin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000033730.10.000e+098.78SMESG000033730.1[more]
SMESG000033730.13.719e-1898.13SMESG000033730.1[more]
SMESG000033728.10.000e+050.30SMESG000033728.1[more]
SMESG000033732.10.000e+043.80SMESG000033732.1[more]
SMESG000053932.13.398e-9931.50SMESG000053932.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004957 ID=SMED30004957|Name=Anoctamin|organism=Schmidtea mediterranea sexual|type=transcript|length=2902bp
TCCGATCTCTGATTTCTAGACAATCACGTGGACGCGTGCGTGTTTGTATG
CGAGTTTGTGTGTGTGTTTGTTTGTGTGCCCATATTTAATTGTGATTCAT
TATCCTGTCCTGCTACGATTAATCGATCATTCATTTAATTATTTGTACAT
GAGACCCGATGTATGATAACCGGTTTTCAACGAAGGATAATGAAAGAATT
CCGAAAACAACAACTAATAATGGATTATTTTTTACTGATGGAATAAGACA
AATCGATTTTGTTCTTGCTTATCAAAAACTAAATGACAATGAGCGGAATC
GAAAAATTCGTTCGAAATTCTTGAAAATTCTTATGAAACAAGGACTGGAA
TTTGAAATTCAAGACGAAGAAGGGAATTTATTTTCTTTGGAAAATTTTGA
TAATCGGGATGATACTGAGAAAATTGTTTTTATCAAACTGTTTGCAAAAT
GGGAAACTCTTTGTCATTATGCGGAATTACTGAGAATTCGGAAACCAATA
TTGCATCCACCGTCAAACATCAAATATGAACAATCATTAAGTTTCCGAAA
ATATTTCAGAAAATTTGATATTTTTAATTTATATTTTGGTAATAGTTTTC
ATTCAAGGACTCACACTTTTACAATGCCATTTTCATCTTCAAAAGAATAT
TTATTTGACATTCCTGCTAATAGACAATACTTTTTTATTCAAACTGAACG
CAGTTTGATTGTTAATTATATTTTGAGAAGCATAACACTTCAATGCAACC
GCAATAAATGCAATATTTTAGCTAATATTATACATCCGAAAAGCACTCCT
TCATCAATTACTGAAATGGAAATGCGTACATTTTCAACCATAAATAGTGA
AAGTGAATGTTCTAAGAGCCATTCAAATAATGATGAAACTGATGAAGGTC
TCACTGAAATACACCATTTAATTCAAACGAATGACAAGTTAACAAATATG
AGCTTACATAATTTGATTTCGGAACAAGTTTTTGAAAGTGCTTATTGTCT
TCATGAGAGTTTTATAGTACAAAATTCTTTGAAGAGAGATGAAAGCGATC
GAGTAAAGCTCTATAAATGTTGGGGCTTGACAAGAAATATTTGTAGATCC
CAACCATTGGATAGTATTAGATCCTATTTTGGTGAGAAAATAGCATTTTA
TTTCAGTTGGCTTGGATTTTATACTTATTGGCTATTTTTTCCCTCTCTGC
TCGGATTGGTAATCGCAGTTTTTAACATACTACATGCATCAAGTGATATT
ATTGTAAATGAAATAAAAGAAGGTGGAAATATTACCATGTGTCCATTATT
GTGTAATTCAAAGCAATGTAAATTTTGGAAATTGTCTGATGTTTATTATA
AATTTTTCGTCATTCGCATTTTGGACAATAAAACCATGATCCTTATGGCT
TTTTCAATGTCAATATGGGCATCTTTATTTTTGGAAATGTGGAAGCGGGA
ACAATTTCGGTTAGCTTTCCATTGGAATGTTTATGATCTTCAAAATCAAT
ATGAGCCACAGAAGCCAGAATTCGTCGCCTTCATCACGCAAAATCAAACC
GATAAAGGAAATGAATCCTCTGTTCCGTTTTGGAGAAGAACAGTACCATT
TATGTTCTTTAAATTTTCAACTGTTTTGTTTTCGGTTATACTTGCGCTGG
CATTTCTTGTTGGTATTATCCTATATGAAATTGTTATATATGCCTTGTTG
ATGATGCATCCAAGTCCTTTGGTGACACAAATGTCCAATGTTATCATATC
CGTCACTGGTTCAATCATATCTCTAATCGTTATCCTTTTACTTACTATGG
TTTATGCTAAACTGGCTCATTGGCTAACAGGTCTGGAAAATAACGAAACT
CAGTCTGAATATGATGATAGCGTCACAATGAAATTATATTTATTAGAGTT
TATCAACAATTATTCGTATTTATTTTATTTTGGTTTCATCTTACCACTCA
TTCAACCAATTCCAGGTTTCAAGGCAATGTCAGACTTGAAACCAATTGGA
TGTCCAACTGGAGGCTGTTTGTTCGGACTTTCAGTTCAGTTGGCATTTAT
TATGATAGGTCGTCAATTGATCAGTCATTTCACAGAATATAGTTACCCTC
TTCTTTGCTCCTCAATCAAAAAGTATAAATTGAGAAAATGTAATAAAGTA
AAATATCGAAGCAAAAATATAACAAATGTTAACGCAGAAATAATTCGATG
TTATGACGATTTATTGCTAGCAGACCTTGAATCTCAACCAGTATTTTATG
AATATCTTGAAATGTTAATCCAATTCGGATTCATCACGATGTTTATTCCG
GCATTCCCTCTGGCACCCCTGTTAGCTCTCTTTAATAATTTATTGGAAAT
TCGAAATGACGCGACAAAATTTTTAACGGCATACAAAAGACCCGTTGCTC
AAAGGGTGAAAGATATTGGAACATGGATAAATATATTATCCGTTGTAGCC
GGACTCGCTGTGAAGTCTAATGCCATACTTATTGCCTTTACAACATTTTT
CATTGAAAGACTTCTTTATATTCTCAAATACAGTCCAACTGGAGATTTAA
AAGGATTTTCAGACTTTACACTTTCTTATCTTAAATCATCGGAATTCGCG
TCTTCCACAAATGAAACATATTGCAGATACATGGATTTCAGGCATCATCC
TTTGGATATCAAAAATGGGCCTCTTACTTTAACTTCAATATACTGGGAGA
TTCTTGCCGCAAAAGTAATCTTCGTATATTTGTTTGAGAATGTAGTTTAC
ACTATAATGAAAATTATTTCTGCCACAATTCCAAATCAAAATGAAAGGAT
TACTAAAGAAATTACAAAGGAAGTCACAATCTCTAGAAAATTACTTTTGA
AATAGAATTCTCGATGACAACATGAAAAATTTTATTATTAATGTATTTCA
AA
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protein sequence of SMED30004957-orf-1

>SMED30004957-orf-1 ID=SMED30004957-orf-1|Name=SMED30004957-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=899bp
MYDNRFSTKDNERIPKTTTNNGLFFTDGIRQIDFVLAYQKLNDNERNRKI
RSKFLKILMKQGLEFEIQDEEGNLFSLENFDNRDDTEKIVFIKLFAKWET
LCHYAELLRIRKPILHPPSNIKYEQSLSFRKYFRKFDIFNLYFGNSFHSR
THTFTMPFSSSKEYLFDIPANRQYFFIQTERSLIVNYILRSITLQCNRNK
CNILANIIHPKSTPSSITEMEMRTFSTINSESECSKSHSNNDETDEGLTE
IHHLIQTNDKLTNMSLHNLISEQVFESAYCLHESFIVQNSLKRDESDRVK
LYKCWGLTRNICRSQPLDSIRSYFGEKIAFYFSWLGFYTYWLFFPSLLGL
VIAVFNILHASSDIIVNEIKEGGNITMCPLLCNSKQCKFWKLSDVYYKFF
VIRILDNKTMILMAFSMSIWASLFLEMWKREQFRLAFHWNVYDLQNQYEP
QKPEFVAFITQNQTDKGNESSVPFWRRTVPFMFFKFSTVLFSVILALAFL
VGIILYEIVIYALLMMHPSPLVTQMSNVIISVTGSIISLIVILLLTMVYA
KLAHWLTGLENNETQSEYDDSVTMKLYLLEFINNYSYLFYFGFILPLIQP
IPGFKAMSDLKPIGCPTGGCLFGLSVQLAFIMIGRQLISHFTEYSYPLLC
SSIKKYKLRKCNKVKYRSKNITNVNAEIIRCYDDLLLADLESQPVFYEYL
EMLIQFGFITMFIPAFPLAPLLALFNNLLEIRNDATKFLTAYKRPVAQRV
KDIGTWINILSVVAGLAVKSNAILIAFTTFFIERLLYILKYSPTGDLKGF
SDFTLSYLKSSEFASSTNETYCRYMDFRHHPLDIKNGPLTLTSIYWEILA
AKVIFVYLFENVVYTIMKIISATIPNQNERITKEITKEVTISRKLLLK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR032394Anoct_dimer
IPR007632Anoctamin
Vocabulary: molecular function
TermDefinition
GO:0046983protein dimerization activity
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007632AnoctaminPFAMPF04547Anoctamincoord: 320..888
e-value: 9.5E-122
score: 407.1
IPR007632AnoctaminPANTHERPTHR12308NGEP-RELATEDcoord: 262..896
IPR007632AnoctaminPANTHERPTHR12308NGEP-RELATEDcoord: 24..200
IPR032394Anoctamin, dimerisation domainPFAMPF16178Anoct_dimercoord: 257..317
e-value: 2.3E-8
score: 34.1
coord: 24..203
e-value: 7.2E-32
score: 110.9
NoneNo IPR availablePANTHERPTHR12308:SF31ANOCTAMINcoord: 24..200
NoneNo IPR availablePANTHERPTHR12308:SF31ANOCTAMINcoord: 262..896
NoneNo IPR availableTMHMMTMhelixcoord: 619..638
NoneNo IPR availableTMHMMTMhelixcoord: 399..421
NoneNo IPR availableTMHMMTMhelixcoord: 576..598
NoneNo IPR availableTMHMMTMhelixcoord: 528..550
NoneNo IPR availableTMHMMTMhelixcoord: 493..515
NoneNo IPR availableTMHMMTMhelixcoord: 759..781
NoneNo IPR availableTMHMMTMhelixcoord: 337..359
NoneNo IPR availableTMHMMTMhelixcoord: 703..725
NoneNo IPR availableTMHMMTMhelixcoord: 837..859