Lysosomal Pro-X carboxypeptidase

Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            V   Y   YF   +DHF + N    F  +YL++ + W K G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG  S+  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++H +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NFL P+PAWP+ V C+ L  P  +   LL   +  + V++NY+GQ++CL  +   T  L   GW+ Q CTE+ MP CT+G+ DMF  + ++      +C   +GV PR  W  T++ GK + + +NIVFSNG LDPWS GGV      ++  + I  GAHH+DLR+ +  D   +  AR LE   +  WI ++  S
Sbjct:   44 VAKNYSVLYFQQKVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDS 491          

Query:  213 FSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            F  K     +  + I+Q  +   Y +  +DHF + N    F  +YL++ + W K G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG  S+  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++H +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NFL P+PAWP+ V C+ L  P  +   LL   +  + V++NY+GQ++CL  +   T  L   GW+ Q CTE+ MP CT+G+ DMF  + ++      +C   +GV PR  W  T++ GK + + +NIVFSNG LDPWS GGV      ++  + I  GAHH+DLR+ +  D   +  AR LE   +  WI ++  S
Sbjct:   53 FQQKALAAGQLHICIIQLNH---YKTPLVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDS 512          

Query:  270 YDTKYFSTYLDHFTYKNDSAK-FQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLL---TDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGL--DDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +  ++F   LDHF ++    K F  ++L+S   WV+G   I FY GNEG +  FANNS FV EL  +   +++FAEHR+YG SLPFG  S     H   L  EQALAD+A+LL  L+  + GA+++P IAFGGSYGGML+A+ R KYP++VAG++AASAPVL V  + + N  FR +T  F+ + +  C   V  A+  IK +        +   F TC+PL     L  L     +    + M +YPYPT+FLGP+PA PV V C  L +      Q +        + +N +G   C          A+P   G   D   W+ Q CTE+ +   ++ +TDMF +  F   +  + C  ++GV PR  W  T FWG  L AASNI+FSNG LDPW+ GG+  + + SV  + I+ GAHH+DLR+SHP D + +  ARKLE   I +W+
Sbjct:   31 FQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQ-RGHTELLTVEQALADFAELLRALRRDL-GAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQ-SPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA----QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWV 473          

Query:  444 VWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYT 1136
            +W++ E+L  M++FAEHR+YG SLPFG  S+  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++H +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NFL P+PAWP+ V C+ L  P  +   LL   +  + V++NY+
Sbjct:    1 MWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYS 233          

Query:  444 VWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNF 1013
            +W++ E+L  M++FAEHR+YG SLPFG  S+  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++H +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NF
Sbjct:    1 MWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNF 192          

Query:  171 FVTLLLMISGFTIAFSVKDYKIK----KFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXX-XXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMV--GNVENCNYAFRVLTRAFKVKG-NEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLT----DGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQ--IRCLPANPITPGL----DDNGWNVQTCTELPMPMCTDGITDMFY--ENRFDKNVNDKNCHLSYG------VSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNP---SVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            F++L ++I+       ++D   +    KF  +I +YKY+  Y    +D F + ND  +F ++Y ++ +++  G  ILFY GNEGS+E FA N+GF+W+L  +L   V+F EHRFYG S PF   SY   +H GYL+S+QALAD    +  +    I GA+ S VIAFGGSYGGML+AWFR KYP+IV G+IAASAPV      N+    Y F ++TRAF   G N   ++    A   + K D      N+         L++ D  IG L     + +  M M NYPYPT+FL  +PAWPV   CK  S P     +     Y  V +++NYTG     C  A           D  GW  QTCTE+ MP+C  G  + F+  +  F      + C  ++          R   G   F    L +ASNIVFSNGYLDPWS GG Y+ S+    SV  +++K GAHH DLR +HP DT +++  R +E  AI KWI E
Sbjct:    4 FISLAILIATTHCLTLLRDPVTQNGASKFEKSIGKYKYEEGYLKAPIDPFAFTND-LEFDLRYFLNIDHYETGGPILFYTGNEGSLEAFAENTGFMWDLAPELKAAVVFVEHRFYGKSQPFKNESYTDIRHLGYLSSQQALADFALSVQFFKNEKIKGAQKSAVIAFGGSYGGMLSAWFRIKYPHIVDGAIAASAPVFWFTDSNIPEDVYDF-IVTRAFLDAGCNRKAIEKGWIALDELAKSDSGRQYLNVLYKLDPKSKLENKDD-IGFLKQYIRESMEAMAMVNYPYPTSFLSSLPAWPVKEACKSASQPGKTQEESAEQLYKIVNLYYNYTGDKSTHCANAAKCDSAYGSLGDPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLAGGLAFGATSLPSASNIVFSNGYLDPWSGGG-YDHSDKVQGSVISVILKQGAHHYDLRGAHPQDTEEVKKVRAMETQAIKKWIKE 498          

Query:  171 FVTLLLMISGFTIAFSVKDYKIK----KFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXX-XXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMV--GNVENCNYAFRVLTRAFKVKG-NEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLT----DGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQ--IRCLPANPITPGL----DDNGWNVQTCTELPMPMCTDGITDMFY--ENRFDKNVNDKNCHLSYG------VSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNP---SVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            F++L ++I+       ++D   +    KF  +I +YKY+  Y    +D F + ND  +F ++Y ++ +++  G  ILFY GNEGS+E FA N+GF+W+L  +L   V+F EHRFYG S PF   SY   +H GYL+S+QALAD    +  +    I GA+ S VIAFGGSYGGML+AWFR KYP+IV G+IAASAPV      N+    Y F ++TRAF   G N   ++    A   + K D      N+         L++ D  IG L     + +  M M NYPYPT+FL  +PAWPV   CK  S P     +     Y  V +++NYTG     C  A           D  GW  QTCTE+ MP+C  G  + F+  +  F      + C  ++          R   G   F    L +ASNIVFSNGYLDPWS GG Y+ S+    SV  +++K GAHH DLR +HP DT +++  R +E  AI KWI E
Sbjct:    4 FISLAILIATTHCLTLLRDPVTQNGASKFEKSIGKYKYEEGYLKAPIDPFAFTND-LEFDLRYFLNIDHYETGGPILFYTGNEGSLEAFAENTGFMWDLAPELKAAVVFVEHRFYGKSQPFKNESYTDIRHLGYLSSQQALADFALSVQFFKNEKIKGAQKSAVIAFGGSYGGMLSAWFRIKYPHIVDGAIAASAPVFWFTDSNIPEDVYDF-IVTRAFLDAGCNRKAIEKGWIALDELAKSDSGRQYLNVLYKLDPKSKLENKDD-IGFLKQYIRESMEAMAMVNYPYPTSFLSSLPAWPVKEACKSASQPGKTQEESAEQLYKIVNLYYNYTGDKSTHCANAAKCDSAYGSLGDPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLAGGLAFGATSLPSASNIVFSNGYLDPWSGGG-YDHSDKVQGSVISVILKQGAHHYDLRGAHPQDTEEVKKVRAMETQAIKKWIKE 498          

Query:  171 FVTLLLMISGFTIAFSVKDYKIK----KFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXX-XXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMV--GNVENCNYAFRVLTRAFKVKG-NEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLT----DGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQ--IRCLPANPITPGL----DDNGWNVQTCTELPMPMCTDGITDMFY--ENRFDKNVNDKNCHLSYG------VSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNP---SVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            F++L ++I+       ++D   +    KF  +I +YKY+  Y    +D F + ND  +F ++Y ++ +++  G  ILFY GNEGS+E FA N+GF+W+L  +L   V+F EHRFYG S PF   SY   +H GYL+S+QALAD    +  +    I GA+ S VIAFGGSYGGML+AWFR KYP+IV G+IAASAPV      N+    Y F ++TRAF   G N   ++    A   + K D      N+         L++ D  IG L     + +  M M NYPYPT+FL  +PAWPV   CK  S P     +     Y  V +++NYTG     C  A           D  GW  QTCTE+ MP+C  G  + F+  +  F      + C  ++          R   G   F    L +ASNIVFSNGYLDPWS GG Y+ S+    SV  +++K GAHH DLR +HP DT +++  R +E  AI KWI E
Sbjct:   65 FISLAILIATTHCLTLLRDPVTQNGASKFEKSIGKYKYEEGYLKAPIDPFAFTND-LEFDLRYFLNIDHYETGGPILFYTGNEGSLEAFAENTGFMWDLAPELKAAVVFVEHRFYGKSQPFKNESYTDIRHLGYLSSQQALADFALSVQFFKNEKIKGAQKSAVIAFGGSYGGMLSAWFRIKYPHIVDGAIAASAPVFWFTDSNIPEDVYDF-IVTRAFLDAGCNRKAIEKGWIALDELAKSDSGRQYLNVLYKLDPKSKLENKDD-IGFLKQYIRESMEAMAMVNYPYPTSFLSSLPAWPVKEACKSASQPGKTQEESAEQLYKIVNLYYNYTGDKSTHCANAAKCDSAYGSLGDPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLAGGLAFGATSLPSASNIVFSNGYLDPWSGGG-YDHSDKVQGSVISVILKQGAHHYDLRGAHPQDTEEVKKVRAMETQAIKKWIKE 559          

Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXX-----TIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVL-MVGNVENCNYAFRVLTRAFKVKG-NEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIG-----LLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLS---TPINNPIQLLNAFYTGVQVFFNYTGQIR---------CLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWG---------QTLFWGKRLEAASNIVFSNGYLDPWSAGGV---YNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFAR 1541
            Y +  LDHFT+  D+  F M+ + +   +  G  I FY GNEG +E F   +G +++L    +  +IFAEHRFYG + PFG  SY    + GYL SEQALADYA+LLT LK       +     + VI+FGGSYGGML+AWFRQKYP+IV G+ A SAP++ M G   +      + +R +   G N   + N  NA   +   D      N + +F      K  +   G      L + +  M M +YPYPT FL P+PAWPVTV C  ++   T  ++   L+ A      +++NY              C        G D+ GW  Q C+E+ M MC  G ++  + N   K++          +    GW          +TL+ G  L  +SN++ + G+LDPWS GG     N++   + ++ I   AHH+DLR  +  D + +  AR
Sbjct:   46 YKNMKLDHFTW-GDTRTFDMRVMWNNTFYKPGGPIFFYTGNEGGLESFVTATGMMFDLAPMFNASIIFAEHRFYGQTQPFGNQSYASLANVGYLTSEQALADYAELLTELKRDNNQFKMTFPAATQVISFGGSYGGMLSAWFRQKYPHIVKGAWAGSAPLIYMNGGGVDPGAFDHITSRTYIDNGCNRFILANAWNATLNLSSTDAGRQWLNNNTVFKLDPRTKIRNQTDGWNLNAYLREAIEYMAMVDYPYPTGFLEPLPAWPVTVACGYMNANGTSFSDK-DLVKAVANAANIYYNYNRDPNFTYCIDFSICGDQGTGGLGGDELGWPWQECSEIIMAMCASGGSNDVFWNECGKDIYQTLQQGCVSIFKSMGWTPKNWNIDAVKTLY-GYDLSGSSNLILTQGHLDPWSGGGYKVDQNNAARGIYVLEIPGSAHHLDLRQPNTCDPNTVTNAR 498          

Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXX-----TIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVL-MVGNVENCNYAFRVLTRAFKVKG-NEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIG-----LLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLS---TPINNPIQLLNAFYTGVQVFFNYTGQIR---------CLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWG---------QTLFWGKRLEAASNIVFSNGYLDPWSAGGV---YNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFAR 1541
            Y +  LDHFT+  D+  F M+ + +   +  G  I FY GNEG +E F   +G +++L    +  +IFAEHRFYG + PFG  SY    + GYL SEQALADYA+LLT LK       +     + VI+FGGSYGGML+AWFRQKYP+IV G+ A SAP++ M G   +      + +R +   G N   + N  NA   +   D      N + +F      K  +   G      L + +  M M +YPYPT FL P+PAWPVTV C  ++   T  ++   L+ A      +++NY              C        G D+ GW  Q C+E+ M MC  G ++  + N   K++          +    GW          +TL+ G  L  +SN++ + G+LDPWS GG     N++   + ++ I   AHH+DLR  +  D + +  AR
Sbjct:   46 YKNMKLDHFTW-GDTRTFDMRVMWNNTFYKPGGPIFFYTGNEGGLESFVTATGMMFDLAPMFNASIIFAEHRFYGQTQPFGNQSYASLANVGYLTSEQALADYAELLTELKRDNNQFKMTFPAATQVISFGGSYGGMLSAWFRQKYPHIVKGAWAGSAPLIYMNGGGVDPGAFDHITSRTYIDNGCNRFILANAWNATLNLSSTDAGRQWLNNNTVFKLDPRTKIRNQTDGWNLNAYLREAIEYMAMVDYPYPTGFLEPLPAWPVTVACGYMNANGTSFSDK-DLVKAVANAANIYYNYNRDPNFTYCIDFSICGDQGTGGLGGDELGWPWQECSEIIMAMCASGGSNDVFWNECGKDIYQTLQQGCVSIFKSMGWTPKNWNIDAVKTLY-GYDLSGSSNLILTQGHLDPWSGGGYKVDQNNAARGIYVLEIPGSAHHLDLRQPNTCDPNTVTNAR 498          

Query:  261 QYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA---ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGS--QHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMD-DPVGLTNLSKIFHTCKPLKSADSL---IGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
            ++KY+ K F   LDHF++  + A F ++YL +     K NA   I FY GNEG IELFA N+GF+WE  E+   +VIFAEHR+YG SLPFG  ++N S  +H  Y   EQ L DYA L+T+    +      PV+AFGGSYGGMLAAWFR KYP++V G++AASAPVL    + +C+  +R++T  F+   NE C  N+  +W + + +     G   +S  FH C  LK+ D L   +  + +   ++ M NYPY ++FL P+PA+PV   C  L    +    LL+A  + + V+ NYT   +CL  + +    DD+GWN+Q+C ++ MP+C++G   MF  + ++     + C+ +Y ++P+       + G+ LEAA+NI+FSNG LDPWS GGV  + N  V +I++  GAHH+DLR S P+D   +R AR  E   I +WI ++
Sbjct:   32 RFKYEIKEFQVPLDHFSFLIN-ATFNIRYLYNDSFVDKSNARTPIFFYTGNEGDIELFAQNTGFLWEQAERQRALVIFAEHRYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYAMLITF----LRNDRQMPVVAFGGSYGGMLAAWFRMKYPHLVNGALAASAPVLQFPGITDCDIFYRIVTSVFQNAYNENCTLNIAKSWKLFETLGASEAGKKQISDAFHLCNALKNDDDLKKFLDYVEEVYSNLAMVNYPYNSSFLAPLPAYPVRQVCYYLKELHSTDADLLHAMSSALAVYTNYTQSAKCLDIS-VNSNADDSGWNIQSCNQMVMPICSNGSETMFRTSSWNFKDYAEKCYKNYRLTPKPYDIILRYGGRNLEAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEGAHHLDLRHSDPADPPSVRDARDKEAAIIARWIQDF 475          

Query:  261 QYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA---ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGS--QHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMD-DPVGLTNLSKIFHTCKPLKSADSL---IGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
            ++KY+ K F   LDHF++  + A F ++YL +     K NA   I FY GNEG IELFA N+GF+WE  E+   +VIFAEHR+YG SLPFG  ++N S  +H  Y   EQ L DYA L+T+    +      PV+AFGGSYGGMLAAWFR KYP++V G++AASAPVL    + +C+  +R++T  F+   NE C  N+  +W + + +     G   +S  FH C  LK+ D L   +  + +   ++ M NYPY ++FL P+PA+PV   C  L    +    LL+A  + + V+ NYT   +CL  + +    DD+GWN+Q+C ++ MP+C++G   MF  + ++     + C+ +Y ++P+       + G+ LEAA+NI+FSNG LDPWS GGV  + N  V +I++  GAHH+DLR S P+D   +R AR  E   I +WI ++
Sbjct:   32 RFKYEIKEFQVPLDHFSFLIN-ATFNIRYLYNDSFVDKSNARTPIFFYTGNEGDIELFAQNTGFLWEQAERQRALVIFAEHRYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYAMLITF----LRNDRQMPVVAFGGSYGGMLAAWFRMKYPHLVNGALAASAPVLQFPGITDCDIFYRIVTSVFQNAYNENCTLNIAKSWKLFETLGASEAGKKQISDAFHLCNALKNDDDLKKFLDYVEEVYSNLAMVNYPYNSSFLAPLPAYPVRQVCYYLKELHSTDADLLHAMSSALAVYTNYTQSAKCLDIS-VNSNADDSGWNIQSCNQMVMPICSNGSETMFRTSSWNFKDYAEKCYKNYRLTPKPYDIILRYGGRNLEAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEGAHHLDLRHSDPADPPSVRDARDKEAAIIARWIQDF 475          

Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA--ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIK-KMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANY--PYPTNFLG---------PMPAWPVTVFCKP-LSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP---------------ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYE------------NRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +F   LDHF   +D   +Q +Y ++ + +   ++  +    G EG         G      E    + +  EHRFYG S P   +S   +++  YL+SEQAL D A  +T +K      +    IAFGGSY G LAAW R+KYP ++ GSI++S P+L    V+   Y F V+  +      E CVD V  +++ ++  +   +G  +L + F TC P+K  DS+         D+ MAN+      NF G         P     +   C   L+T    P+  L      V           CL                 +    G+    W  QTC E      +D   D F +            + F KN+N K   L    +          +G      +N+++ +G +DPW A G+  S+N ++  I I+  AH  ++     +D   +  AR    N I+K++++
Sbjct:   58 WFEQRLDHFK-SSDKRTWQQRYFVNADFYRNDSSAPVFLMIGGEGEASAKWMREGAWVHYAEHFGALCLQLEHRFYGKSHPTADLS---TENLHYLSSEQALEDLASFVTAMKVKFNLGDGQKWIAFGGSYPGSLAAWAREKYPELIYGSISSSGPLL--AEVDFKEY-FEVVKASLAAYKPE-CVDAVTRSFAQVEILLKHMIGQRSLDEKFKTCTPIK--DSIEN-------DLDMANFFENLAGNFAGVVQYNKDNSPHATITIDDICDVMLNTTAGPPVTRLGL----VNDMLLKESNTTCLDYKYDKMVADMKNVSWDSETAKGM--RQWTYQTCHEFGFYQTSDNPADTFGDRFGVDFFIRQCMDVFSKNMNAKFLKLVVSATND-------NYGALKPKTTNVLYVHGSIDPWHALGLVKSTNAALPTIYIEGTAHCANMYEPVKTDPPQLVAAR----NKILKFLAK 498          

Query:  276 TKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSL-IGLLTDGLFDMGMANYPYPTNFLGPMP---AWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDD---NG-----WNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYG--VSPRWGWGQT----LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSD 1526
            T +    LDHF    ++  +QM+Y+++   +  G  +  Y G E  I       G ++++ ++ + ++ + EHR+YG S P   +S   +++  YLN  Q+LAD A  +  +K    G  +S VI  GGSY   +  WF++ YP++VAG  A+SAP+L    V    Y   +  ++ +  G  AC   + N  + ++ M        +  +   C+P      L +  L   + D+          F G +    A  +   C+ +    N+ I +       + VF    G+   L  + IT  L D   NG     W  QTC E      T G +   +  +F        C   YG   S  +   Q      F+G       N+  ++G LDPW A G+ + +    Q  +I   AH  D  S   SDT++
Sbjct:   47 TLWIEQKLDHFD-PEETRTWQMRYMLNDALYQSGAPLFIYLGGEWEISSGRITGGHLYDMAKEHNALLAYTEHRYYGQSKPLPDLS---NENIKYLNVNQSLADLAYFINTIKQNHEGLSDSKVIIVGGSYSATMVTWFKKLYPDLVAGGWASSAPLL--AKVNFVEYK-EITGQSIEQMGGSACYKRIENGIAEMETMIATKRGAEVKALLKLCEPFDVYSDLDVWTLFSEISDI----------FAGVVQTHNAGQIEGVCEKIMAGSNDLIGVAGYL---LDVFEESGGKCYDLSYDAITALLLDTNYNGNIMRQWIFQTCNEYGWYQ-TSGSSAQPFGTKFPVTYYTTMCADLYGSEYSNEFISNQVSITNQFFGGLFPNVENVYLTHGQLDPWRAMGIQDET----QATIIPEHAHCKDFNSISSSDTAE 456          

Query:  276 TKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSL-IGLLTDGLFDMGMANYPYPTNFLGPMP---AWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDD---NG-----WNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYG--VSPRWGWGQT----LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSD 1526
            T +    LDHF    ++  +QM+Y+++   +  G  +  Y G E  I       G ++++ ++ + ++ + EHR+YG S P   +S   +++  YLN  Q+LAD A  +  +K    G  +S VI  GGSY   +  WF++ YP++VAG  A+SAP+L    V    Y   +  ++ +  G  AC   + N  + ++ M        +  +   C+P      L +  L   + D+          F G +    A  +   C+ +    N+ I +       + VF    G+   L  + IT  L D   NG     W  QTC E      T G +   +  +F        C   YG   S  +   Q      F+G       N+  ++G LDPW A G+ + +    Q  +I   AH  D  S   SDT++
Sbjct:   47 TLWIEQKLDHFD-PEETRTWQMRYMLNDALYQSGAPLFIYLGGEWEISSGRITGGHLYDMAKEHNALLAYTEHRYYGQSKPLPDLS---NENIKYLNVNQSLADLAYFINTIKQNHEGLSDSKVIIVGGSYSATMVTWFKKLYPDLVAGGWASSAPLL--AKVNFVEYK-EITGQSIEQMGGSACYKRIENGIAEMETMIATKRGAEVKALLKLCEPFDVYSDLDVWTLFSEISDI----------FAGVVQTHNAGQIEGVCEKIMAGSNDLIGVAGYL---LDVFEESGGKCYDLSYDAITALLLDTNYNGNIMRQWIFQTCNEYGWYQ-TSGSSAQPFGTKFPVTYYTTMCADLYGSEYSNEFISNQVSITNQFFGGLFPNVENVYLTHGQLDPWRAMGIQDET----QATIIPEHAHCKDFNSISSSDTAE 456          

Query:  270 YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSADSLIGL---LTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPI---QLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            Y+T Y    +DHF +  ++  F+ +YL++ ++W K G  ILFY GNEG I  F NN+GF+W++ E+L  +++FAEHR+YG SLPFG+ SY+ +++  YL SEQ LAD+A L+  LK +  GAE S VIA GGSYGGMLAAW R KYPN V G++AASAP+     +  C   +RV+TR F + G+     ++ ++W+ I ++     GL  LS+ F  C PLKS + + G    L +   ++ M +YPY  +FL P+PAWPV V CK L    N  +   QLLN     V+V++NYTG   CL  +    G L   GW  Q+CTE+ MPMCTDGI DMF    +        C+  +GV PR  W +T++ G+ + A SNI+FSNG LDPW +GGV  S + S+  I+I  GAHH+DLR ++  D   +  AR LE     +WI
Sbjct:   47 YNTLYIDQQIDHFGFL-ENGTFKQRYLLNDQHWHKDGGPILFYTGNEGDITWFCNNTGFMWDVAEELGALLVFAEHRYYGESLPFGEESYSNAKYLNYLTSEQVLADFAVLIKALKKSQPGAEKSSVIAIGGSYGGMLAAWLRMKYPNAVVGALAASAPIWQF--IVPCGEFYRVVTRDFTISGSNC-SSSIRSSWAAIDRLSATGEGLQWLSQTFGLCGPLKSQEDVFGFKAWLQETWVNLAMVDYPYEADFLQPLPAWPVKVVCKNLQ--FNKGVSDKQLLNGVSQAVRVYYNYTGDAVCLNTSKTATGNLGFLGWFYQSCTEMVMPMCTDGINDMFEPQPWSFQAFSDECYNQFGVRPREDWAETVYGGRNIHAHSNIIFSNGNLDPWMSGGVTKSLSESLLAIMIDGGAHHLDLRYNNELDPQSVIKARSLEVQYFKQWI 484          

Query:  198 GFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKG-NAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK---PLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            G T A  V++Y  +      +   +  KYF   LDHF Y +  +  +  +YLI+ + W KG   I FY GNEG I  FA NSGF+ EL      ++IFAEHR+YG SLPFGK S+   +  G L  EQALADYA ++T LK  + G +  PVI FGGSYGGML+ + R +YPNIVAG++AASAP+L    + +    F+ +T  F+ K N AC + V  A+  +  +        +   F  CK     K    L G L +    M M +YPY T+F+G MPA+PV V C+ +     N   L++A    V + +N TG++ C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F +   ++ C   +GV PR GW +T FWG  L  ASNI+FSNG LDPW+ GG+  S +PS+  I I  GAHH+DLR S+P+D   +  ARK E   I +W+
Sbjct:   17 GKTEARPVENYSNEITSHRDLSLDFKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEELGG-QTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIML----NGTDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDMFPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 483          

Query:  270 YDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKG-NAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK---PLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +  KYF   LDHF Y +  +  +  +YLI+ + W KG   I FY GNEG I  FA NSGF+ EL      ++IFAEHR+YG SLPFGK S+   +  G L  EQALADYA ++T LK  + G +  PVI FGGSYGGML+ + R +YPNIVAG++AASAP+L    + +    F+ +T  F+ K N AC + V  A+  +  +        +   F  CK     K    L G L +    M M +YPY T+F+G MPA+PV V C+ +     N   L++A    V + +N TG++ C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F +   ++ C   +GV PR GW +T FWG  L  ASNI+FSNG LDPW+ GG+  S +PS+  I I  GAHH+DLR S+P+D   +  ARK E   I +W+
Sbjct:   50 FKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEELGG-QTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIML----NGTDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDMFPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 492          

Query:  270 YDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKG-NAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK---PLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +  KYF   LDHF Y +  +  +  +YLI+ + W KG   I FY GNEG I  FA NSGF+ EL      ++IFAEHR+YG SLPFGK S+   +  G L  EQALADYA ++T LK  + G +  PVI FGGSYGGML+ + R +YPNIVAG++AASAP+L    + +    F+ +T  F+ K N AC + V  A+  +  +        +   F  CK     K    L G L +    M M +YPY T+F+G MPA+PV V C+ +     N   L++A    V + +N TG++ C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F +   ++ C   +GV PR GW +T FWG  L  ASNI+FSNG LDPW+ GG+  S +PS+  I I  GAHH+DLR S+P+D   +  ARK E   I +W+
Sbjct:   50 FKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEELGG-QTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIML----NGTDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDMFPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 492          

Query:  270 YDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKG-NAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK---PLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +  KYF   LDHF Y +  +  +  +YLI+ + W KG   I FY GNEG I  FA NSGF+ EL      ++IFAEHR+YG SLPFGK S+   +  G L  EQALADYA ++T LK  + G +  PVI FGGSYGGML+ + R +YPNIVAG++AASAP+L    + +    F+ +T  F+ K N AC + V  A+  +  +        +   F  CK     K    L G L +    M M +YPY T+F+G MPA+PV V C+ +     N   L++A    V + +N TG++ C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F +   ++ C   +GV PR GW +T FWG  L  ASNI+FSNG LDPW+ GG+  S +PS+  I I  GAHH+DLR S+P+D   +  ARK E   I +W+
Sbjct:   50 FKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEELGG-QTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIML----NGTDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDMFPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 492          

Query:  180 LLLMISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            LLL+ +  ++  S +    +++  +     Y+T YF+  +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:   20 LLLLSAAHSVRLSRQFGSAQQYGSSNPGPSYETYYFTQQVDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 490          

Query:  297 LDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWK 1586
            +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++++
Sbjct:    5 VDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQFE 438          

Query:  297 LDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:   19 VDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 450          

Query:  297 LDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:   21 VDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 452          

Query:  297 LDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:    5 VDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAD 436          

Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            V  KY   YF   +DHF +  D   F+ +YL++ ++W + G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG+ S+  SQH  +L SEQALAD+A+L+ +L+ TI GA+  PVIA GGSYGGMLAAWFR KYP+IV G++AASAP+  +  +  C    +++T  F+ K    C +++  +W+VI K+     GL +L+ I H C PL S    +L G + +   ++ M NYPY  NFL P+PAWP+   C+ L  P  +   LL   +  + V++NY+GQ  CL  +   T  L   GW+ Q CTE+ MP CT+GI DMF    +D      +C   +GV PR  W  T++ GK + + SNI+FSNG LDPWS GGV      ++  I I +GAHH+DLR+ +  D S +  +R LE   + KWI
Sbjct:   42 VARKYSVLYFEQKVDHFGFA-DMRTFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIWQLDGMVPCGEFMKIVTNDFR-KSGPYCSESIRKSWNVIDKLSGSGSGLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSDTVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWI 483          

Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            V  KY   YF   +DHF +  D   F+ +YL++ ++W + G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG+ S+  SQH  +L SEQALAD+A+L+ +L+ TI GA+  PVIA GGSYGGMLAAWFR KYP+IV G++AASAP+  +  +  C                                     GL +L+ I H C PL S    +L G + +   ++ M NYPY  NFL P+PAWP+   C+ L  P  +   LL   +  + V++NY+GQ  CL  +   T  L   GW+ Q CTE+ MP CT+GI DMF    +D      +C   +GV PR  W  T++ GK + + SNI+FSNG LDPWS GGV      ++  I I +GAHH+DLR+ +  D S +  +R LE   + KWI
Sbjct:   42 VARKYSVLYFEQKVDHFGFA-DMRTFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIWQLDGMVPCG-----------------------------------SGLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSDTVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWI 448          

Query:  252 NIVQYKYDTKYFSTYLDHFTYKNDSAK-FQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPL---KSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPIT--PGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWIS 1577
             ++   +   YF  Y+DHF +++   K F  ++L+S + W  G   I FY GNEG I  FANNSGF+ EL  Q   +++FAEHR+YG SLPFG  S     +   L  EQALAD+A LL  L+  + G  ++P IAFGGSYGGML+A+ R KYP++VAG++AASAPV+ V  + +    FR +T  F  + +  C   V +A+  IK +        +S+ F TC+ L   K    L G   +    + M +YPYPT+FLGP+PA PV V C+ L     N  Q +        + +N +G   C          A+P     G D   W+ Q CTE+ +   ++ +TDMF E  F + +  + C  ++GV PR  W QT FWG  L+AASNI+FSNG LDPW+ GG+ ++ + SV  + I+ GAHH+DLR+S+  D   +   RKLE   I +W++
Sbjct:   35 RVLDPDFHENYFEQYMDHFNFESFGNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSFANNSGFMVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRG-YTQLLTVEQALADFAVLLQALRQDL-GVHDAPTIAFGGSYGGMLSAYMRMKYPHLVAGALAASAPVVAVAGLGDSYQFFRDVTADFYGQ-SPKCAQAVRDAFQQIKDLFLQGAYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCQRLL----NEGQRIMGLRALAGLVYNSSGTEPCYDIYRLYQSCADPTGCGTGSDARAWDYQACTEINLTFDSNNVTDMFPEIPFSEELRQQYCLDTWGVWPRQDWLQTSFWGGDLKAASNIIFSNGDLDPWAGGGIQSNLSTSVIAVTIQGGAHHLDLRASNSEDPPSVVEVRKLESTLIREWVA 484          

Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILF-YCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAF-RVLTRAFKVKGNEACVDNVHNAWSVIKKM--DDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLN--AFYTGVQVFFNYTGQIRCLP------------ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSP---RWGWGQT-LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            +    LD F   +D   F  +Y ++ ++    +  +F + G EGS+   +  +G    L      +VI  EHRFYG S+P G +         YL+S  ALAD A     L   +  + +SP I FGGSY G LA W R K+P++V  ++A+SAP+  V +    N    R LT+   + G+  C+     A++ ++++    P     L +    C  L   +    LL   L  +      Y      P+    V   C  L     N  +          VQ+     GQ +CL               P   G+ D  W  QTCTE    +  +G+   F +         + C   +G+SP        QT  ++G +   A+ ++F NG  DPW    V      S   +LI + +H  D+    PSD+  +R  R+     +  W+ + K S
Sbjct:   60 WLEQPLDPFN-ASDRRTFLQRYWVNDQHRTGQDVPVFLHIGGEGSLGPGSVMAGHPAALAPAWGALVISLEHRFYGLSMPAGGLDLA---LLRYLSSRHALADVASARQALSGLLNVSSSSPWICFGGSYAGSLATWARLKFPHLVFAAVASSAPLSAVVDFSAYNQVVARSLTQ-VAIGGSLECLAAASTAFTEVERLLRAGPAAQAVLREELGACGSLDLTEDQAELL-GALQALVGGTVQYDGQAGAPL---SVRQLCGLLLGKWGNRSRSTPYLGLRRAVQIVLRSMGQ-KCLSFSRAETVAQLSNTEPQVSGVGDRQWLYQTCTEFGFYVTCEGLQCPFSQLP-ALPFQLELCEQVFGLSPASVAQAVAQTNSYYGGQSPGATQVLFVNGDTDPWHVLSVTQDLGLSEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKISQQLQDWLKDIKKS 507          

Query: 1161 NPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENR---FDKNVNDKNCHLSYGVSPR---WGWGQT-LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
             P   G+ D  W  QTCTE    +  +G+   F +     F   +    C   +G+SP        QT  ++G +   A+ ++F NG  DPW    V      S   +LI + +H  D+    PSD+  +R  R+     +  W+ + K S
Sbjct:   21 EPQVSGVGDRQWLYQTCTEFGFYVTCEGLQCPFSQLPALPFQLEL----CEQVFGLSPASVAQAVAQTNSYYGGQSPGATQVLFVNGDTDPWHVLSVTQDLGLSEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKISQQLQDWLKDIKKS 167          

Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            V  KY   YF   +DHF +  D   F+ +YL++ ++W + G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG+ S+  SQH  +L SEQALAD+A+L+ +L+ TI GA+  PVIA GGSYGGMLAAWFR KYP+IV G++AASAP+  +  +  C    +++T  F+ K    C +++  +W+VI K+     GL +L+ I H C PL S    +L G + +   ++ M NYPY  NFL P+PAWP+   C+ L  P  +   LL   +  + V++NY+GQ  CL  +   T  L   GW+ Q CTE+ MP CT+GI DMF    +D      +C   +GV PR  W  T++ GK + + SNI+FSNG LDPWS GGV      ++  I I +GAHH+DLR+ +  D S +  +R LE   + KWI
Sbjct:   42 VARKYSVLYFEQKVDHFGFA-DMRTFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIWQLDGMVPCGEFMKIVTNDFR-KSGPYCSESIRKSWNVIDKLSGSGSGLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSDTVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWI 483          

Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            V   Y   YF   +DHF + N    F  +YL++ + W K G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG  S+  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++H +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NFL P+PAWP+ V C+ L  P  +   LL   +  + V++NY+GQ++CL  +   T  L   GW+ Q CTE+ MP CT+G+ DMF  + ++      +C   +GV PR  W  T++ GK + + +NIVFSNG LDPWS GGV      ++  + I  GAHH+DLR+ +  D   +  AR LE   +  WI ++  S
Sbjct:   44 VAKNYSVLYFQQKVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDS 491          

Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            V   Y   YF   +DHF + N    F  +YL++ + W K G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG  ++  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++  +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NFL P+PAWP+ V C+ L  P  +   LL   +  + V++NY+GQ++CL  +   T  L   GW+ Q CTE+ MP CT+G+ DMF  + ++      +C   +GV PR  W  T++ GK + + +NIVFSNG LDPWS GGV      ++  + I  GAHH+DLR+ +  D + +  AR LE   +  WI ++  S
Sbjct:   44 VAKNYSVLYFQQKVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNTFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIRRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPTSVLLARSLEVRHMKNWIRDFYDS 491          

Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPL-KSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCK-------PLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCL-PANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +  KY  +Y    +DHF +  D   F+ +YLI+   W + G +ILFY GNEG I  F NN+GF+W++ E++  M++FAEHR+YG SLPFG  S++ S+H  +L +EQALAD+A L+ YLK TI GA N  VIA GGSYGGMLAAWFR KYP++V G++A+SAP+    ++  C+   +++T  F   G   C +++  +W  I ++     GL  LS+  H C PL KS D   L   +++   ++ M +YPY +NFL P+PAWPV V C+       P +  + N  Q LN       V++NY+GQ +CL  +   T  L   GW+ Q CTE+ MP C+DG+ DMF  + ++      +C   +GV PR  W  T++ GK + + +NI+FSNG LDPWS GGV      ++  I+I NGAHH+DLR+S+  D   ++  R LE   + +WIS+
Sbjct:   46 ITLKYSIRYIQQKVDHFGFNIDRT-FKQRYLIADNYWKEDGGSILFYTGNEGDIIWFCNNTGFMWDIAEEMKAMLVFAEHRYYGESLPFGADSFSDSRHLNFLTTEQALADFAKLIRYLKRTIPGARNQHVIALGGSYGGMLAAWFRMKYPHLVVGALASSAPIWQFNDLVPCDIFMKIVTTDFSQSGPN-CSESIRRSWDAINRLAKKGTGLRWLSEALHLCTPLTKSQDVQRLKDWISETWVNVAMVDYPYESNFLQPLPAWPVKVVCQYFKYSNVPDTVMVQNIFQALN-------VYYNYSGQAKCLNVSETATSSLGVLGWSYQACTEMVMPTCSDGVDDMFEPHSWNMKEYSDDCFKQWGVRPRPSWIPTMYGGKNISSHTNIIFSNGELDPWSGGGVTKDITDTLLAIVIPNGAHHLDLRASNALDPVSVQLTRSLEVKYMKQWISD 490          

Query:  270 YDTKYFSTYLDHFTYKNDSAK-FQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLL---TDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGL--DDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +  ++F   LDHF ++    K F  ++L+S   WV+G   I FY GNEG +  FANNS FV EL  +   +++FAEHR+YG SLPFG  S     H   L  EQALAD+A+LL  L+  + GA+++P IAFGGSYGGML+A+ R KYP++VAG++AASAPVL V  + + N  FR +T  F+ + +  C   V  A+  IK +        +   F TC+PL     L  L     +    + M +YPYPT+FLGP+PA PV V C  L +      Q +        + +N +G   C          A+P   G   D   W+ Q CTE+ +   ++ +TDMF +  F   +  + C  ++GV PR  W  T FWG  L AASNI+FSNG LDPW+ GG+  + + SV  + I+ GAHH+DLR+SHP D + +  ARKLE   I +W+
Sbjct:   31 FQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQ-RGHTELLTVEQALADFAELLRALRRDL-GAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQ-SPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA----QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWV 473          

Query:  180 LLLMISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            LLL+ +  ++  S +    +++  +     Y+T YF+  +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:   23 LLLLSAAHSVRLSRQFGSAQQYGSSNPGPSYETYYFTQQVDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 493          

Query:  180 LLLMISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            LLL+ +  ++  S +    +++  +     Y+T YF+  +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:   20 LLLLSAAHSVRLSRQFGSAQQYGSSNPGPSYETYYFTQQVDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 490          

Query:  180 LLLMISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLIGL---LTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            LL++++  + + S +    +++  +     Y T YF+  +DHF +  D A F+ +YL+S  +W K G  ILFY GNEG I  F NN+GF+W++ +++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA++SPVIA GGSYGGMLAAWFR KYP++V G++A+SAP+    ++  CN  ++++T  FK K    C ++V N+W  I +M +   GL  LSK FH C PLK+ + ++G    L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG  +CL  +    G L D GW+ Q CTE+ MP C+DG+TDMF    +D     + C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  ILI  GAHH+DLRS++  D   +  AR LE   + KWI +
Sbjct:   23 LLMILAAHSFSLSRQVGSGQQYGSSTPGPNYQTYYFTQQVDHFGFFED-ATFKQRYLVSAAHWKKPGGPILFYTGNEGDITWFCNNTGFMWDVAKEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQDSPVIALGGSYGGMLAAWFRMKYPDVVVGAVASSAPIWQFEDLVPCNEYYQIVTNDFK-KSGPGCSESVRNSWEAINRMAETSDGLQWLSKAFHLCCPLKNKEDVVGFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKNPKSGDKDLLQDIFQAVNVYYNYTGDTQCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVTDMFEPQSWDFQAYSEECNKQWGVRPRGSWITTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLVAILIPEGAHHLDLRSNNDCDPKSVLLARGLEVEYMKKWIEQ 493          

Query:  270 YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSADSLIGL---LTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            Y  +YF   +DHF + +D+  FQ +YLI+ ++W K N  ILFY GNEG +  F+NN+GF+W++ ++L+ MV+FAEHR+YG SLPFG  SY+ S+   YL SEQALAD+A L+ +LK+TIAGA  SPVIA GGSYGGMLAAWFR KYP++V G++AASAP+   G++  C   F ++T+ FK  G   C +++ N+WS I ++     GL  LSK FH C PLK+   +  L   L+D   ++ M NYPY  +FL P+PAWP+   CK L  P  +   LL   +  + +++NY+GQI C   A   T  L   GWN QTCTE+ MP+CTDG+ DMF   ++D     + C+  +GV PR  W  +++ GK + + SNI+FSNG LDPWSAGGV  + + S+  I+I  GAHH+DLR  +PSD   ++ AR LE   + +WI
Sbjct:   33 YLIRYFQQQVDHFGF-DDNLTFQQRYLIADQHWKKNNGPILFYTGNEGDVTWFSNNTGFMWDVAQELNAMVVFAEHRYYGESLPFGNESYSDSKRLNYLTSEQALADFAVLIEHLKSTIAGARYSPVIAIGGSYGGMLAAWFRMKYPHLVVGALAASAPIWQFGDLVPCGAFFSIVTKDFKRSGT-GCAESIRNSWSAIDRLSSTDEGLLWLSKTFHLCSPLKNLQDVAVLKRGLSDTWINLAMMNYPYKADFLEPLPAWPIEEVCKFLKDPSLSDRLLLQNVFQAINIYYNYSGQILCFDMAETATKSLGHLGWNYQTCTEMVMPLCTDGVNDMFEPQKWDLKARSEECYKLWGVRPRPSWIISMYGGKNIHSHSNIIFSNGGLDPWSAGGVTRNISHSLVAIMIPEGAHHLDLRGRNPSDPKSVQQARDLELCYMKQWI 471          

Query:  207 IAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKM-DDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQ-----LLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYN-SSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
            I+F++  ++I+        + Y+ K F+ +LDHF++   S KF + YLISTE W  G  ILFY GNEGSIE FA N+G ++EL E L+  VIFAEHR+YG+SLPFG  S+N  +HFGYL +EQALADYA LLT  K       NSPVI+FGGSYGGML AWFRQ YPN+V G +AASAP+ +   + +C   ++V TRA++  G   C   +   WS+I ++   P GL +LS  F TC+   S D + G + D L  + M NYPY T+FLG +PAWPV  FCK +   +N PI+      +  F       +NY  + +CL     +  LD  GW +QTC E+  P+C+DG TDMF    +D      +C   +GV PR  W    +W K +   + ++FSNG LDPWSA GV N +S P   ++ I  GAHH+DLR SHP+DT ++R AR L ++ I  WI EW
Sbjct:   15 ISFAILSHRIRPSKKFQSPFSYEKKSFTEFLDHFSF-GPSHKFNITYLISTEKWKPGGPILFYTGNEGSIEHFARNTGLIFELAENLTGAVIFAEHRYYGTSLPFGNQSFNDRRHFGYLIAEQALADYAKLLTDFKCANHQFANSPVISFGGSYGGMLTAWFRQAYPNVVTGGLAASAPIWLFPGMCDCRGFYQVTTRAYQQGGGSQCTSTIREIWSLIDEIAKKPHGLDDLSGAFKTCELFSSGDFVSGFVEDYLVTLAMGNYPYSTSFLGELPAWPVKEFCKAI---VNCPIEGKLPPQVEKFACAFFSLYNYKQEDKCLSFASGSENLDSRGWELQTCMEMTNPICSDGKTDMFRPRGWDPIEFSNSCQDRFGVQPRMDWAGLQWWAKDIITDTRLIFSNGDLDPWSAFGVLNETSAPGATVVRIGRGAHHLDLRGSHPNDTEEVRAARGLIRDKIASWIEEW 476          

Query:  228 YKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNP-IQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYN--SSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +++ + +       Y T Y    +DHF +  ++  F+ +YL++  +W K N+ ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG  SY+ +++  YL SEQALAD+A L+  LK T  GA+NSPVIA GGSYGGML+AW R KYP+ V G++AASAP+    ++  C   ++++T+ F + G   C +N+  +W  I  +     GL  LS+ F  C PLK  D     G L +   ++ M +YPY  NFL P+P WP+ V C  LS   + P  +LL+     V V++NYTG   CL  +    G L   GW  Q+CTE+ MPMCTDGI DMF    ++       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPW +GGV      + S+  I+I +GAHH+DLR ++  D   +  AR +E     KWI +
Sbjct:   39 HRVTRSLPQQRPVSYTTLYLDQQIDHFGFL-ENGTFKQRYLLNDLHWHKDNSPILFYTGNEGDITWFCNNTGFMWDIAEELGAMLVFAEHRYYGESLPFGDESYSNAKYLNYLTSEQALADFAVLIENLKKTYPGAQNSPVIAIGGSYGGMLSAWLRMKYPSAVVGALAASAPIWQFTDMVPCGDFYKIVTQDFAISGFN-CSNNIRRSWMAINNVSSTDEGLQWLSEEFRLCSPLKEEDVSGFKGWLQETWVNLAMVDYPYEANFLQPLPRWPIKVVCSYLSFVTDVPDKELLHGISQAVNVYYNYTGNAECLNISLTATGNLGIRGWFYQSCTEMVMPMCTDGIQDMFEPQPWNFQAFSDECYDLFGVRPREHWADTVYGGKNICSHSNIIFSNGRLDPWMSGGVTRLCGVSDSLVAIVIPDGAHHLDLRYNNEYDPETVIRARAVEVQYFKKWIKQ 495          

Query:  267 KYDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK-PLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            ++  KYF+  LDHF Y +  +  +  +YLI+ + W KG+  I FY GNEG I  FA NSGFV EL  + + +VIFAEH      +P          + G L  EQALADYA ++T LK  +  AE  PVI FGGSYGGML+ + R +YPNIV G++AASAP+L    + +    FR +T  F+   +  C D+V +A+  ++ +        +   F  CK P  S D   L G L +    + M +YPY T+F+  MPA+PV V C+ +     N  ++L+A    V + +N TG+  C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F +++ ++ C   + V PR GW +T +WG  L  ASNI+FSNG LDPW+ GG+  S + S+  I I  GAHH+DLR+S+P+D   +  AR+ E   I +W+
Sbjct:   25 QFKEKYFTQILDHFNYNSLGNGTYPQRYLITDQYWKKGSGPIFFYTGNEGDIWDFALNSGFVLELAVEQAALVIFAEHD-KSFIIP----------NVGLLTVEQALADYAVMITDLKKELR-AEKCPVIVFGGSYGGMLSVYMRVRYPNIVTGALAASAPILSTAGMGDSGQFFRDVTADFE-NCSPVCKDSVRSAFQKLQTLAQQEDYAGIQSAFSLCKTPSSSKDIHQLNGFLRNAFTLLAMMDYPYKTSFMSVMPAFPVKVACETML----NGTEVLSALRDTVGIVYNSTGEHACYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDMFPPMPFTESMREEYCARRWAVVPRPGWLKTQYWGDALSTASNIIFSNGDLDPWANGGIRKSLSDSLIAINIPEGAHHLDLRASNPADPDSVIKARQTEAKLIAQWV 458          

Query:  297 LDHFTYKNDSAKFQMKYLISTENWVKGNAILF-YCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAF---KVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFD--MGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQV--FFNYTGQIRCLPANPITPGLDDN----------GWNVQTCTELPM-PMCTDGITDMFYENRFDKNVNDKNCHLSYGVS----PRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSA-GGVYNSSNPSV-QIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            LDHF  +N +  F  ++ I+   W   +  +F Y G EG +  F+  +G    + +Q   +++  EHRFYG S+  G +     Q+  YL+S+QALAD A    ++         +  I+FGGSY G L+AWFR K+P++V G++A+SAPV     ++  +Y   V+ R+     V G+E CV  V  A++ ++        T + K F  C+  KS +    LL   L D  MG   Y      L       +   C  ++      ++   A+   V++   +    +  CL  +     LD N           W  QTCTE      C D      +    +     + C L + +     P       L++G        +++ NG  DPW A   V N +N    + ILI + AH  D+  +   D + +  AR+  ++ +  W+
Sbjct:   59 LDHFNRRN-TRTFPQRFFINEAYWKHPHGPVFLYIGGEGPLSEFSVLAGHHVTMAKQQGALLVALEHRFYGRSIIPGGLE---PQNLQYLSSQQALADLAAFHQHISQKYNLTYRNIWISFGGSYAGALSAWFRGKFPHLVYGAVASSAPV--QAKLDFSSYT-TVVGRSLMDESVGGSEKCVKAVWEAFAAVEAALLRGEETQVGKDFSCCETPKSLEDQTELLR-SLADIFMGTVQYNEEVGLL------TIARLCSIMTNQSKAYVEGKEAYDRLVRLAAIYRTMEKETCLEVSYEKSILDLNTTTHVSSGYRQWFYQTCTEFGFYQTCEDATCP--FSRMMNLQTEIQLCPLLFSIPQHTLPSNIAFTNLYYGGDQPQTQRVLYVNGDTDPWMALSVVRNGTNKDKHRAILIHSSAHCADMNPTRARDRASLLQARQEIESLVEAWL 493          

Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLK---SADS--LIGLLTDGLFDMGMANYPYPTNFLGPMPA-WPVTVFCKP-LSTPINNPIQLLNAFYTGVQVFF-------NYTGQIRCLPANPITPGLDDNG--WNVQTCTELPMPMCTDGITDMF------YENRFDKNVNDKNCHLSYGVSPRWGWGQT-LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDI 1529
            +F   LDHF    DS  ++ +Y I+   +  G  +    G EG         G      E+   + +  EHRFYG S P   +S    +   +L+S QALAD A   +    T     N   +AFGGSY G LAAWFR KYP++V  S+A SAPV    N         V+ ++ + +  +  V     + +++ ++ DP    N++K F  C  L+     DS  L+  L     D+   N      F G +     + V C   L + +  P     A    +Q  F        Y+  +R +     T      G  W  QTC E      TD     F      Y  R   ++ + N  ++  V       QT   +G     ++ IVF NG +DPW A GV ++    +  + IK  AH  ++   +P+   D+
Sbjct:   54 WFIQRLDHFN-GADSRVWKQRYFINDRFYKPGGPVFLMIGGEGPANPAWMQYGTWLNYAEKFGALCLLLEHRFYGKSHPTEDLSV---ESLRFLSSRQALADLAHFRSVTAETRKLTSNK-WVAFGGSYPGSLAAWFRLKYPHLVHASVATSAPVYATVNFTE---YLEVVQKSLEAENPQCPVLVKKASDTLMARLKDPKTYDNITKDFRLCSKLEIQSDMDSAYLLETLAGNFMDVVQYNEDNRA-FEGVLGTNITIKVLCDVMLDSLLGEPYDRYAAVARLLQKTFLQSCTDAQYSQYVREMSNTSWTGPAASGGRQWVYQTCAEFGFYQSTDSQNQPFGGFPLKYHLRQCNDIYNLNSSVADAVQ------QTNEEYGGYDIRSTRIVFPNGSIDPWHALGVISNITDELPAVFIKGTAHCANM---YPARAEDL 474          

Query:  813 KGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK-PLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGL--DDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWIS 1577
            K N  C D V   +  +KK+ D      +++    C+ P  +AD   + G   +    + M +YPY  +F+G +PA PV V C  L     N    L+     V +F+N +G  +CL         A+P   GL  D   W+ Q CTE+ +   T+ ++DMF    +      + C   +GV PR  W  T +WGK + ++SNI+FSNG LDPW  GG  +    +V + +I  GAHH+DLR S+P+D   +  ARKLE   +  W++
Sbjct:    4 KYNPKCPDIVRAGFIELKKLADKQEWAQIAQRMRLCQAPSSAADVRHMYGWARNTFTYLAMLDYPYAASFMGSLPANPVNVACDLLL----NSKDPLDGLMQAVALFYNTSGTAKCLDPAAEFIECADPTGCGLGPDSLAWDYQACTEINLLCSTNNVSDMFPALPYTAAARREYCAKRWGVVPRETWLATQYWGKDVNSSSNIIFSNGNLDPWGNGGFQHDVGGNVAVKVI-GGAHHLDLRYSNPADPESVVTARKLESALLHTWLA 266          

Query:  279 KYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILF-YCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSL-PFG-KMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAF---YTGVQ-------VFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLF----WGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWK 1586
            ++    LDHF  +     ++ +Y ++  NW K +  +F + G EG++  +   +G   EL  +   +V   EHRFYG S+ P G KM     ++  YL+S+QALAD A    YL  T     N+  I FGGSY G L+AWFR K+P++V  ++A+SAPV    + +  N           V G++ C+  V  A++ +        L+ L + F +C P    D L  L    L D+ M+   Y       MP   +   C  +     +  Q L A    Y  ++        + N+   +    A  +  G+    W  QTCTE           D  +      + N   C   +GV P        F    +G      S I+F NG +DPW A  V  +   S   I I   AH  ++  + PSD   +  AR      +  W+ + K
Sbjct:   73 RFLQQPLDHFDRRTKET-YKQRYWVNNMNWKKPDGPVFLFIGGEGALSEYDVLAGEHVELSAKYGALVAAVEHRFYGESINPDGLKM-----ENLQYLSSQQALADLASFHAYLVDTYNLTRNNTWICFGGSYPGSLSAWFRLKFPHLVFAAVASSAPVRAQLDFQGYNKVVAASLADKVVGGSDKCLSRVREAFATVDAKLTGKELSGLERDFKSCVPFAGPDDL-ALFASNLADIFMSVVQYNRE----MPNSDIRALCAAMIDTGKSAYQQLVALNENYLSIEQRNCSDNTYANFIADLSNTTATRVGVGM--RQWTYQTCTEFGYYQTCVSERDCPFLQLMTLSWNLDLCDRVFGVDPASVASAVRFTNEYYGADHPRGSRILFVNGDIDPWHALSVLRNETRSEVAIFINGTAHCANMSPTSPSDPPSLTNARLKIDEQVGDWLHQAK 512          

Query:  333 FQMKYLISTENWVKGNAILF-YCGNEGSIELFANNSGFVWE---LGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPV-IAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKM 872
            F+ +  +++  W +    +F Y G E ++    +N  FV +   L +    +++ AEHRFYG S+    +S    ++  YL   QALAD   +  Y  +   G +     ++FGGSY G L+AWFR K+P ++  ++A+SAPV    +    +       R   V G++ CV ++   +    K+
Sbjct:   16 FKQRVWVNSLFWKRPRGPVFLYIGGESALN---SNDVFVGQHVRLAQSHGALLVAAEHRFYGKSVNEEGLS---DKNLRYLTISQALADLVRVHHYYVSDEFGLKQGHAWVSFGGSYPGSLSAWFRLKHPELIHTAVASSAPVRAQLDYAGYDEVVGQSLRNSMVGGSDECVSSMREGFENGDKL 194          

Query:  297 LDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMD-DPVGLTNLSKIFHTCKPLKSADSLIGL---LTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
            LDHF ++  SA F  +YL++  NW KG  I FY GNEG I  FANN+GF+W+  ++   M++FAEHR+YG +LPFGK SY   ++ GYL+SEQALAD+A L+ ++K T  GA  SPVIA GGSYGGML++W R KYPN+V  ++AASAP+L    +  C     ++T+ F   G ++CV+++  +WSVI+K+     G   L+ +F+TC P+K+  ++  L   L++   ++ M NYPY   FL P+PAWP+   C  L+      + LL A    V V++N +GQ +C   +      L D GW+ Q CTE+ MPMC+DG+ DMF   ++D     ++C  SYGV PR  W +  + G+ + A SNI+FSNG LDPW AGGV  S +PS+  +L++ GAHH+DLR S+P+D   +  AR+ EK  + +WISE+
Sbjct:    1 LDHFNFRT-SATFSQRYLVNIANWRKGGPIFFYTGNEGDITWFANNTGFMWDNAKEFGAMLVFAEHRYYGETLPFGKRSYESPKYLGYLSSEQALADFATLIRHIKLTTPGATGSPVIAIGGSYGGMLSSWIRMKYPNLVTAALAASAPILYFQGLTPCEGFNEIVTKDFHRDGGDSCVNSIRKSWSVIEKLGATQSGRKTLTSVFNTCSPIKTKYNVTQLQDWLSETWANLAMVNYPYAATFLEPLPAWPIKKVCSHLTDADLPDVALLKAVAGAVGVYYNSSGQAKCFNLSQQAVSSLGDKGWDFQACTEMVMPMCSDGVNDMFKPVKWDFEAFAESCQGSYGVKPRQYWVEVQYGGRDISAHSNIIFSNGLLDPWFAGGVTKSLSPSLVAVLVEEGAHHLDLRHSNPADPPSLIKARQTEKEYLHRWISEY 433          

Query:  267 KYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIK--KMDDPVGLTNLSKIFHTCKPLKSADS---LIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAF---YTG----VQVFFNYTGQIRCLPANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWIS 1577
            ++ T  F   +DHF +   S  F+ +YL + + W     I FY GNEG I  F  NSGFV+E  +  S +VIF EHR+YG SLPFG+ S+   ++ GYL+ EQALAD+A L+  LK     AE  PV++FGGSYGGML+A+ R KYPN++  ++AASAP+  + ++   ++ F  +TR FK   +  C D V   +  +   K +   GL  +SK F  CKPLKSAD    LIG + +    + M +YPY T+FL P+PA PV   CK L+T  +    L +A    Y G    ++ F  +T  + C  A+P   GL +    W+ Q CTELPMP  T+ +TDMF    +  ++    C   + V PR  W     WG+ +  ASNI+FSNG LDPW  GGV  S +PS+  +L++ GAHH+DLRSS+P D   +  AR++E   I KWIS
Sbjct:    2 QFKTGTFEQTVDHFNFIQ-SGTFKQRYLYTEKYWDGKGPIFFYSGNEGGITGFWENSGFVFEAAKNFSALVIFGEHRYYGESLPFGQDSFK-IENIGYLSIEQALADFATLIPALKKQFK-AEEKPVVSFGGSYGGMLSAYLRFKYPNVIQAALAASAPIYFIADLSIRDFFFPAVTRDFK-NADPKCPDLVRAGFIELDNLKKEGLKGLDAISKAFKLCKPLKSADQINHLIGWIRNAFTIIAMCDYPYATDFLAPLPANPVNYACKLLATASDRLSGLADAAGLAYNGTSGTLKCFDPWTEFVEC--ADPTGCGLGNANLAWDYQACTELPMPAGTNNVTDMFPVLPWTLDMRADYCQKHWQVKPRLEWPGISLWGRDISTASNIIFSNGNLDPWRPGGVLKSVSPSLVAVLVEGGAHHLDLRSSNPEDPPSVVAAREMELELIRKWIS 446          

Query:  270 YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIK--KMDDPVGLTNLSKIFHTCKPLKSADS---LIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNA 1100
            + T  F   +DHF +   S  F+ +YL + + W     I FY GNEG I  F  NSGFV+E  +  S +VIF EHR+YG SLPFG+ S+   ++ GYL+ EQALAD+A L+  LK     AE  PV++FGGSYGGML+A+ R KYPN++  ++AASAP+  + ++   ++ F  +TR FK   +  C D V   +  +   K +   GL  +SK F  CKPLKSAD    LIG + +    + M +YPY T+FL P+PA PV   CK L+T  +    L +A
Sbjct:    1 FKTGTFEQTVDHFNFIQ-SGTFKQRYLYTEKYWDGKGPIFFYSGNEGGITGFWENSGFVFEAAKNFSALVIFGEHRYYGESLPFGQDSFK-IENIGYLSIEQALADFATLIPALKKQFK-AEEKPVVSFGGSYGGMLSAYLRFKYPNVIQAALAASAPIYFIADLSIRDFFFPAVTRDFK-NADPKCPDLVRAGFIELDNLKKEGLKGLDAISKAFKLCKPLKSADQINHLIGWIRNAFTIIAMCDYPYATDFLAPLPANPVNYACKLLATASDRLSGLADA 278          

Query:  285 FSTYLDHFTYKNDSAKFQMKYLISTENWVKG--NAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPL-KSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFY------TGVQVFFNYTGQIRCLPANPITP-GLD-DNGWNVQTCTELPMPMCTDGITDMFYENRF----DKNVNDKNCHLSYG-VSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            F  Y+DHF +      +  +Y ++   W KG    +L Y G E  +       G + ++ ++   ++   EHR+YG S  FG +    +++  YL+S+ ALAD A  + + K      + +  I +GGSY G L+AWFR KYP++V G++A+SAPV    + ++ N        +  V G++ C+ N+  A+  + ++ D      L K F  C  + K  D+ +       F MG+  Y         +P   +   CK ++    +P + L+  Y      T     F+Y   ++ +      P G D    W  Q+CT+       +  T   +  R     D ++  +   ++ G +  R  +    + GKR    S IVF NG +DPW +  V  +   S   + I   +H  ++ ++ P+D   +  AR+     + +W+ E + +
Sbjct:   61 FEQYIDHFEFTPRPRTYLQRYWMNRAFW-KGPDGPVLLYVGGESVLSGGYIAGGHIVDIAKEYGALLFAVEHRYYGKSNFFGCLK---TKNMRYLSSQLALADLAQFVAHAKNKFGLTDKNKWITYGGSYPGSLSAWFRIKYPHLVIGAVASSAPVEAQTDFKDYNNVVASSLSSPLVGGSKLCMHNIEEAFKFVDRLLDTKNFKTLEKDFIACNDISKLNDTWMFASNLAGFFMGLVQYN------NQVPGINIAYVCKQMNNASRSPYKSLSILYKQQIQKTASCSDFSYENFMKTVKTQKRDPDGFDMIRQWYYQSCTQFGYFQTCEPGTHCVFSKRLGIINDMDLCQEVFEIALGQLKARINFTNEYYGGKR-PRGSKIVFVNGSIDPWHSLSVVTNQTSSEVAVFIPGTSHCANMGANQPNDPPALVEARRRVTAIVGEWLKEAQAA 501          

Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKK-MDDPVGLTNLSKIFHTCKPL-KSADSLIGLLTD---GLFDMGMANYPYPTNFLGPMPAWPVTV--FCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPA---NPI----------TPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +F   LDHF   N     Q  Y   T    K + +    G EG+I       G + +  E    M    EHRFYG S P   MS     +  YLNSEQALAD A     +        +S  I+FGGSY G L+AW R KYP+++ G++A+SAPVL   N         V+T + +  G + C  N+ NA + I++ +D   G   L+ +F  C+PL +  D+ +   +    GLF MG+  Y         +P   +T+   C  ++     P  +    Y  +      T   +CL A   N I          +       W  QTCTE      TD     F + RF    + + C   +G +         F    L  AS I  +N     +   G+ +S +    +      AH  ++     SD+  ++ AR++ K  I KW+
Sbjct:   18 WFIQRLDHFDDSNTETWKQRFYYNDTFRKTKDSPVFLMVGGEGAISPVWVLIGNMMKYAEGFGAMAFILEHRFYGQSHPRSDMS---DANLKYLNSEQALADLAAFRQAMSVKF-NLTDSKWISFGGSYPGSLSAWLRLKYPHLIHGAVASSAPVLAQLNFPEY---LEVVTASLETTGPD-CTKNIANATAAIEELLDADEGTKKLTNLFRVCEPLNRRNDNDVSTFSSNLAGLF-MGVVQYNKDNRAFEGVPGTNITIATVCGIMNDKSLGPALMR---YAKLNSLILDTYGEKCLDASYQNAINSLRNVSWDSSAAEGGRQWTYQTCTEFGFYQTTDSDNQPFGK-RFPLKYSIQQCMDVFGEA---------FNSSNL--ASGIRQTN---TNYGGKGIASSRDIVFVVFYPTGTAHCANMYPESDSDSPQLKQAREVIKQHIAKWL 441          

Query:  270 YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKS-ADSLI--GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLS-TPINNPIQLLNAFYTGVQVFFNYTGQIRCL-PANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWK 1586
            Y T YF+  ++HF +  D   F+ +YL++ ++W + +  ILFY GNEG I  F NN+GF+WE+ E+L  M++FAEHR+YG SLPFG+ SY+ S+H  YL SEQALAD+A L+  LK+ +     SPVI+ GGSYGGML+AW R KYPN+V G++AASAP+     +  C   ++++T+ F  K  + C   +  +W  I  +     GL  LS+ F  C PLK+  D++I  G L +   ++ M +YPY  +FL P+PAWP+ V CK L+     +   LL+      +V++NYTG   CL  +   T  L   GW  Q CTE+ MPMCTDG+ DMF    ++       C+  +GV PR  W  TL+ GK + + SNI+FSNG LDPWSAGGV  +   S+  I+I +GAHH+DLR S   D   +R AR LE     +WI + K
Sbjct:   52 YKTFYFNQRINHFGFLED-GTFKQRYLVADKHWQEPDGPILFYTGNEGDITWFCNNTGFMWEIAEELGAMLVFAEHRYYGESLPFGQDSYSDSKHLNYLTSEQALADFAVLIQNLKSKMP---ESPVISVGGSYGGMLSAWLRMKYPNVVVGALAASAPIWQFPRMVGCGDFYKIVTQDF-AKSGQNCDVTIRRSWKAINNLSSTASGLQWLSEEFSLCSPLKTKTDAVIFKGWLQETWVNLAMVDYPYEASFLQPLPAWPIQVVCKYLAFDSKASDYDLLHGVSQAAKVYYNYTGSSSCLNTSQTATSSLGALGWTYQACTEMVMPMCTDGVQDMFEPEDWNFQAFSDECYSMFGVRPREDWAGTLYGGKDISSHSNIIFSNGGLDPWSAGGVTYNITESLVSIMIPDGAHHLDLRYSTDLDPPSVRAARALELKFFQEWIDKTK 492          

Query:  267 KYDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSAD---SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            ++  KYFS  +DHF + +  +  F  +YLI+   W + +  + FY GNEG I  FA NSGF+ EL  Q   +VIFAEHR+YG SLPFG  S++  +  G L  EQALADYA ++T LK  + GA  SPVIAFGGSYGGML+ + R KYPNIVAG++AASAP+L    + +    FR +T  F+ + + AC   V  A+  +++  +    +++      C+P  SA     L GLL +    M M +YPY T+F+G +PA PV V C    T +  P  L N   T   V+ N +G + C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F ++     C   +GV PR GW +  FWG  L AASNI+FSNG LDPW+ GGV  S +PS+  I I  GAHH+DLR S+ +D   +  ARK+E   I  W+
Sbjct:   34 QFTEKYFSQVVDHFNFNSLGNRTFNQRYLITDRFWRRSSGPVFFYTGNEGDIWEFALNSGFIMELAAQQEALVIFAEHRYYGRSLPFGNNSFSIPE-VGLLTVEQALADYALMITELKLQL-GAAQSPVIAFGGSYGGMLSVYMRLKYPNIVAGALAASAPILSTAGLGDPRQFFRDVTADFE-RVSPACRGAVTAAFQQLREAAERRDYSHIQAELSLCQPPSSAQDVHQLYGLLRNAFTLMAMLDYPYSTHFMGSLPANPVKVACD---TMLGGPDLLTNLRDTAGMVY-NSSGLLPCFDLYSLYVECADPTGCGLGFNSLAWDYQACTEIEMCYESNNVTDMFPAMTFTEDARQLYCSKRWGVQPRPGWLRLQFWGDDLSAASNIIFSNGDLDPWANGGVRTSLSPSLIAINISGGAHHLDLRGSNAADPESVIKARKMEAELIAAWV 477          

Query:  273 DTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNV-ENCNYAFRVLTRAFKVKGNEACVDNVHNAW-SVIKKMDDPVGLTNLSKIFHTCKPLK---SADS--LIGLLTDGLFDMGMANYPYPTNFLGPMPA-WPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPA----------NPITPGLDDNG---WNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPR---WGWGQT-LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            + ++F+  LDHF    DS  ++ +Y ++   +  G  +    G EG        +G      E+L  + +  EHR+YG S P   +S N   +  YL+S QALAD A   T +     G  N+  +AFGGSY G LAAWFR KYP++V  S+A SAPV    N  E     +R L        N  C   V  A  S+++K+ DP    N++K F+ C  L+     DS   + +L     D+   N      F G       + V C  +S P    +    A Y  V      T  ++CL A          N    G   NG   W  QTCTE      TD     F    F  +   K C   Y +S         QT  ++G     +S IVF NG +DPW A G+       +  + IK  AH  ++  +   D   +  AR      + +W+
Sbjct:   45 EEQWFTQKLDHFN-GADSRAWKQRYFLNEAFYKPGGPVFLMIGGEGPANPAWMKNGTWLIYAEKLGALCLMLEHRYYGKSHPTLDLSTN---NLRYLSSRQALADLAHFRTVMGEA-QGLTNNKWVAFGGSYPGSLAAWFRLKYPHLVHASVATSAPVHATVNFPEYLEVVWRSLASE-----NAKCPLLVKKASDSLVEKLKDPETFDNITKDFNLCSKLQIQTEMDSAYFLEMLAGNFMDVVQYNED-NREFEGVQGGNITIKVLCDVMSDP---SLGDAYARYAAVARLLMDTFSLKCLDASFSNYLRDMTNTSWEGPSANGGRQWVYQTCTEFGFYQSTDSPNQPF--TGFPLDYQLKQCADFYNISAEQVAQAVAQTNEYYGGYNIKSSRIVFPNGSIDPWHALGITQDITADLPAVFIKGTAHCANMYPARSQDLPQLSLARDHVLLLLQQWL 487          

Query:  342 KYLISTENWVKGNAILF-YCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSL-PFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVH-------------NAWSVIKK----MDDPVGLTNLSKI---FHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPAN---PITPGLD---------DNGWNVQTCTE 1217
            K+ ++  +W + +  +F + G EG I  F   +G   E+ +Q   +++  EHRFYG S+ P G  +    +    L+S+QALAD A    Y+  +   +  +P I+FGGSY G L+AWFR K+P++V  ++A+SAP+    +  + N+   V  R        AC  +++               W+ +++    ++  +   NLS++   F+ C+  K+ D  I L+ + L D+ M    Y  N  G + +  V   C  ++   N+  +  +  +  VQV+ + T + +CL  +    I   +D         +  W  QTCTE
Sbjct:   14 KFFVNEAHWQRPDGPVFLFIGGEGPIFSFDVLAGHHVEMAQQHGALLLAVEHRFYGDSINPDGLKT----ESLADLSSQQALADLATFHGYICRSFNLSSRNPWISFGGSYSGALSAWFRGKFPSLVYAAVASSAPIKAKLDFSDYNH---VNVRVNASTCLHACDSSLYLSDCRFWLSLLFLQCWAQVQQAFAAVEAELLTGNLSQVAGDFNCCQIPKNLDDQIELMQN-LADLFMGTVQY--NEEGVLLS--VKELCDLMTNMCNS--EPSSRSFVSVQVYRSST-EDKCLDVSHEETIKHLMDTSVHSSRRAERQWTYQTCTE 324          

Query:  165 MGFVTLLLMISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            MGFVTLLLMISGFTIAFSVKDYKIKKF VNI QYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQALADYADLLTYLKATIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNV NAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS
Sbjct:    1 MGFVTLLLMISGFTIAFSVKDYKIKKFDVNIEQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQALADYADLLTYLKATIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVRNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 476          

Query:  189 MISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            MISGFTIAFSVKDYKIKKF VNI QYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQALADYADLLTYLKATIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNV NAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS
Sbjct:    1 MISGFTIAFSVKDYKIKKFDVNIEQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQALADYADLLTYLKATIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVRNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 468          

Query:  225 DYKIKKFIVNIVQYK--YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLST-PINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITP-GLDDNGWNVQTCTELPMPMCTDGITDMFY-ENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
             Y   K I  +  YK  Y+T+YF TY+DHFT+KN+S KF +KYLIST+ W KGN ILFYCGNE +IE FA  SG +WELGEQLS +V+FAEHR+YGSSLPFG  S++ +++FGYL  EQ +ADYA LLTYLK+ I GA  SPVIAFGGSYGGMLAAW R KY NIVAGSI++SAP LMVGN +NCN  F+V+++ ++ +G++ C +N+   W +IK +++  GL +LSKIFH C+PLK  ++LI  L   LF++ +AN+PY  +   P+PAWPV  FCK  +   +++   +L +FY  +Q++ N T   +CL          +   W +QTC ELP PMC +GI D+++ EN   +   +  C   YG+ PR  W   LF G   ++ SNI+FSNG LDPWSAGG+  SSN  +Q+I I NGAHHVDLR SHP DT+DI+ ARKLEK  I KWISEW
Sbjct:   11 SYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNYALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEW 468          

Query:  225 DYKIKKFIVNIVQYK--YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLST-PINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITP-GLDDNGWNVQTCTELPMPMCTDGITDMFY-ENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
             Y   K I  +  YK  Y+T+YF TY+DHFT+KN+S KF +KYLIST+ W KGN ILFYCGNE +IE FA  SG +WELGEQLS +V+FAEHR+YGSSLPFG  S++ +++FGYL  EQ +ADYA LLTYLK+ I GA  SPVIAFGGSYGGMLAAW R KY NIVAGSI++SAP LMVGN +NCN  F+V+++ ++ +G++ C +N+   W +IK +++  GL +LSKIFH C+PLK  ++LI  L   LF++ +AN+PY  +   P+PAWPV  FCK  +   +++   +L +FY  +Q++ N T   +CL          +   W +QTC ELP PMC +GI D+++ EN   +   +  C   YG+ PR  W   LF G   ++ SNI+FSNG LDPWSAGG+  SSN  +Q+I I NGAHHVDLR SHP DT+DI+ ARKLEK  I KWISEW
Sbjct:   20 SYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNYALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEW 477          

Query:  297 LDHFTY----KNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP--VGLTNLSKIFHTCKPLKS-ADSLIGL--LTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRC-------LPANPITP---GLDDNGWNVQTCTELPMPMCTDGIT-DMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSN--PSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            LDHF +    +  + KF+ +YL   + +  G  I FYCGNEGSIE F NN+GF++EL  + + +V+F EHR+YG SLPFG ++     +  YL+ EQALAD+  +++Y+K     A NS VIAFGGSYGG LAA+ R KYPNIV G++AAS+P+  V   +  +  F ++T+ F    N  CV+ V + +  +  +      GL  +S+   TCKPL S AD    +  L +    + M +YPY TNF+G +PA+PV V C+ +    NNPI  L        VF+N +  ++C       +  + IT    G D   W+ Q CTE+ +    +  + DMF +    K   D++C   + +       + L WG  +  A+N++FSNG LDPWS GG+ ++S+  PS   +LI+ GAHH+DLRSS+P+D   +R  R++E+  I  W+
Sbjct:   35 LDHFNFLSVSRGYAIKFKQRYLYEDKWYKPGGPIFFYCGNEGSIEGFWNNTGFMFELAPKFNALVVFGEHRYYGVSLPFGSINSFQQPYIQYLSVEQALADFVYMISYVKDKF-NANNSDVIAFGGSYGGCLAAYMRFKYPNIVLGALAASSPIGWVSGSKGFHKFFEIITKDF-YDINPKCVEIVQDGFEEMITLAGKGLTGLDTISRYLKTCKPLTSMADVTYAMKWLRNAFVMLAMMDYPYKTNFMGSLPAFPVNVSCQNILANKNNPIIALR---EAAAVFYNQSKPLKCFSPMDLYIECSDITGCGLGPDSLAWDFQACTEMKLYDDNNATSADMFPDLPLTKKDVDRHCMKKFEIQRAPNQLKFLEWGNDVRTATNVIFSNGNLDPWSLGGIVSNSSLQPSSVALLIQGGAHHLDLRSSNPADPPSVRTVRQIEEKYIRAWL 477