Lysosomal Pro-X carboxypeptidase

Overview
NameLysosomal Pro-X carboxypeptidase
Smed IDSMED30004948
Length (bp)1837
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Lysosomal Pro-X carboxypeptidase (SMED30004948) t-SNE clustered cells

Violin plots show distribution of expression levels for Lysosomal Pro-X carboxypeptidase (SMED30004948) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Lysosomal Pro-X carboxypeptidase (SMED30004948) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Lysosomal Pro-X carboxypeptidase (SMED30004948) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30004948

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30004948SMESG000015438.1 Contig466GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30004948SMESG000074424.1 Contig1592GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30004948SMESG000074424.1 Contig1592GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30004948SMESG000074424.1 Contig466GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30004948SMESG000074424.1 dd_Smed_v4_1351_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30004948SMESG000074424.1 dd_Smed_v4_1351_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30004948SMESG000074424.1 dd_Smed_v4_1351_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30004948SMESG000074424.1 Contig48832newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30004948SMESG000074424.1 Contig48832uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Match: PRCP (prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGNC:9344])

HSP 1 Score: 365.54 bits (937), Expect = 1.094e-119
Identity = 191/450 (42.44%), Postives = 275/450 (61.11%), Query Frame = 3
Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            V   Y   YF   +DHF + N    F  +YL++ + W K G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG  S+  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++H +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NFL P+PAWP+ V C+ L  P  +   LL   +  + V++NY+GQ++CL  +   T  L   GW+ Q CTE+ MP CT+G+ DMF  + ++      +C   +GV PR  W  T++ GK + + +NIVFSNG LDPWS GGV      ++  + I  GAHH+DLR+ +  D   +  AR LE   +  WI ++  S
Sbjct:   44 VAKNYSVLYFQQKVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDS 491          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Match: PRCP (prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGNC:9344])

HSP 1 Score: 362.459 bits (929), Expect = 3.419e-118
Identity = 192/465 (41.29%), Postives = 281/465 (60.43%), Query Frame = 3
Query:  213 FSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            F  K     +  + I+Q  +   Y +  +DHF + N    F  +YL++ + W K G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG  S+  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++H +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NFL P+PAWP+ V C+ L  P  +   LL   +  + V++NY+GQ++CL  +   T  L   GW+ Q CTE+ MP CT+G+ DMF  + ++      +C   +GV PR  W  T++ GK + + +NIVFSNG LDPWS GGV      ++  + I  GAHH+DLR+ +  D   +  AR LE   +  WI ++  S
Sbjct:   53 FQQKALAAGQLHICIIQLNH---YKTPLVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDS 512          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Match: DPP7 (dipeptidyl peptidase 7 [Source:HGNC Symbol;Acc:HGNC:14892])

HSP 1 Score: 308.531 bits (789), Expect = 1.298e-97
Identity = 182/450 (40.44%), Postives = 255/450 (56.67%), Query Frame = 3
Query:  270 YDTKYFSTYLDHFTYKNDSAK-FQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLL---TDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGL--DDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +  ++F   LDHF ++    K F  ++L+S   WV+G   I FY GNEG +  FANNS FV EL  +   +++FAEHR+YG SLPFG  S     H   L  EQALAD+A+LL  L+  + GA+++P IAFGGSYGGML+A+ R KYP++VAG++AASAPVL V  + + N  FR +T  F+ + +  C   V  A+  IK +        +   F TC+PL     L  L     +    + M +YPYPT+FLGP+PA PV V C  L +      Q +        + +N +G   C          A+P   G   D   W+ Q CTE+ +   ++ +TDMF +  F   +  + C  ++GV PR  W  T FWG  L AASNI+FSNG LDPW+ GG+  + + SV  + I+ GAHH+DLR+SHP D + +  ARKLE   I +W+
Sbjct:   31 FQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQ-RGHTELLTVEQALADFAELLRALRRDL-GAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQ-SPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA----QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWV 473          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Match: PRCP (prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGNC:9344])

HSP 1 Score: 199.904 bits (507), Expect = 2.037e-59
Identity = 103/234 (44.02%), Postives = 152/234 (64.96%), Query Frame = 3
Query:  444 VWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYT 1136
            +W++ E+L  M++FAEHR+YG SLPFG  S+  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++H +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NFL P+PAWP+ V C+ L  P  +   LL   +  + V++NY+
Sbjct:    1 MWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYS 233          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Match: PRCP (prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGNC:9344])

HSP 1 Score: 167.162 bits (422), Expect = 1.110e-47
Identity = 88/193 (45.60%), Postives = 128/193 (66.32%), Query Frame = 3
Query:  444 VWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNF 1013
            +W++ E+L  M++FAEHR+YG SLPFG  S+  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++H +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NF
Sbjct:    1 MWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNF 192          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Match: pcp-5 (Prolyl carboxy peptidase like protein 5 [Source:UniProtKB/Swiss-Prot;Acc:P34676])

HSP 1 Score: 308.531 bits (789), Expect = 7.789e-98
Identity = 197/499 (39.48%), Postives = 269/499 (53.91%), Query Frame = 3
Query:  171 FVTLLLMISGFTIAFSVKDYKIK----KFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXX-XXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMV--GNVENCNYAFRVLTRAFKVKG-NEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLT----DGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQ--IRCLPANPITPGL----DDNGWNVQTCTELPMPMCTDGITDMFY--ENRFDKNVNDKNCHLSYG------VSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNP---SVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            F++L ++I+       ++D   +    KF  +I +YKY+  Y    +D F + ND  +F ++Y ++ +++  G  ILFY GNEGS+E FA N+GF+W+L  +L   V+F EHRFYG S PF   SY   +H GYL+S+QALAD    +  +    I GA+ S VIAFGGSYGGML+AWFR KYP+IV G+IAASAPV      N+    Y F ++TRAF   G N   ++    A   + K D      N+         L++ D  IG L     + +  M M NYPYPT+FL  +PAWPV   CK  S P     +     Y  V +++NYTG     C  A           D  GW  QTCTE+ MP+C  G  + F+  +  F      + C  ++          R   G   F    L +ASNIVFSNGYLDPWS GG Y+ S+    SV  +++K GAHH DLR +HP DT +++  R +E  AI KWI E
Sbjct:    4 FISLAILIATTHCLTLLRDPVTQNGASKFEKSIGKYKYEEGYLKAPIDPFAFTND-LEFDLRYFLNIDHYETGGPILFYTGNEGSLEAFAENTGFMWDLAPELKAAVVFVEHRFYGKSQPFKNESYTDIRHLGYLSSQQALADFALSVQFFKNEKIKGAQKSAVIAFGGSYGGMLSAWFRIKYPHIVDGAIAASAPVFWFTDSNIPEDVYDF-IVTRAFLDAGCNRKAIEKGWIALDELAKSDSGRQYLNVLYKLDPKSKLENKDD-IGFLKQYIRESMEAMAMVNYPYPTSFLSSLPAWPVKEACKSASQPGKTQEESAEQLYKIVNLYYNYTGDKSTHCANAAKCDSAYGSLGDPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLAGGLAFGATSLPSASNIVFSNGYLDPWSGGG-YDHSDKVQGSVISVILKQGAHHYDLRGAHPQDTEEVKKVRAMETQAIKKWIKE 498          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Match: pcp-5 (Prolyl carboxy peptidase like protein 5 [Source:UniProtKB/Swiss-Prot;Acc:P34676])

HSP 1 Score: 308.531 bits (789), Expect = 7.789e-98
Identity = 197/499 (39.48%), Postives = 269/499 (53.91%), Query Frame = 3
Query:  171 FVTLLLMISGFTIAFSVKDYKIK----KFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXX-XXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMV--GNVENCNYAFRVLTRAFKVKG-NEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLT----DGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQ--IRCLPANPITPGL----DDNGWNVQTCTELPMPMCTDGITDMFY--ENRFDKNVNDKNCHLSYG------VSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNP---SVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            F++L ++I+       ++D   +    KF  +I +YKY+  Y    +D F + ND  +F ++Y ++ +++  G  ILFY GNEGS+E FA N+GF+W+L  +L   V+F EHRFYG S PF   SY   +H GYL+S+QALAD    +  +    I GA+ S VIAFGGSYGGML+AWFR KYP+IV G+IAASAPV      N+    Y F ++TRAF   G N   ++    A   + K D      N+         L++ D  IG L     + +  M M NYPYPT+FL  +PAWPV   CK  S P     +     Y  V +++NYTG     C  A           D  GW  QTCTE+ MP+C  G  + F+  +  F      + C  ++          R   G   F    L +ASNIVFSNGYLDPWS GG Y+ S+    SV  +++K GAHH DLR +HP DT +++  R +E  AI KWI E
Sbjct:    4 FISLAILIATTHCLTLLRDPVTQNGASKFEKSIGKYKYEEGYLKAPIDPFAFTND-LEFDLRYFLNIDHYETGGPILFYTGNEGSLEAFAENTGFMWDLAPELKAAVVFVEHRFYGKSQPFKNESYTDIRHLGYLSSQQALADFALSVQFFKNEKIKGAQKSAVIAFGGSYGGMLSAWFRIKYPHIVDGAIAASAPVFWFTDSNIPEDVYDF-IVTRAFLDAGCNRKAIEKGWIALDELAKSDSGRQYLNVLYKLDPKSKLENKDD-IGFLKQYIRESMEAMAMVNYPYPTSFLSSLPAWPVKEACKSASQPGKTQEESAEQLYKIVNLYYNYTGDKSTHCANAAKCDSAYGSLGDPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLAGGLAFGATSLPSASNIVFSNGYLDPWSGGG-YDHSDKVQGSVISVILKQGAHHYDLRGAHPQDTEEVKKVRAMETQAIKKWIKE 498          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Match: pcp-5 (Prolyl carboxy peptidase like protein 5 [Source:UniProtKB/Swiss-Prot;Acc:P34676])

HSP 1 Score: 307.76 bits (787), Expect = 6.902e-97
Identity = 197/499 (39.48%), Postives = 269/499 (53.91%), Query Frame = 3
Query:  171 FVTLLLMISGFTIAFSVKDYKIK----KFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXX-XXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMV--GNVENCNYAFRVLTRAFKVKG-NEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLT----DGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQ--IRCLPANPITPGL----DDNGWNVQTCTELPMPMCTDGITDMFY--ENRFDKNVNDKNCHLSYG------VSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNP---SVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            F++L ++I+       ++D   +    KF  +I +YKY+  Y    +D F + ND  +F ++Y ++ +++  G  ILFY GNEGS+E FA N+GF+W+L  +L   V+F EHRFYG S PF   SY   +H GYL+S+QALAD    +  +    I GA+ S VIAFGGSYGGML+AWFR KYP+IV G+IAASAPV      N+    Y F ++TRAF   G N   ++    A   + K D      N+         L++ D  IG L     + +  M M NYPYPT+FL  +PAWPV   CK  S P     +     Y  V +++NYTG     C  A           D  GW  QTCTE+ MP+C  G  + F+  +  F      + C  ++          R   G   F    L +ASNIVFSNGYLDPWS GG Y+ S+    SV  +++K GAHH DLR +HP DT +++  R +E  AI KWI E
Sbjct:   65 FISLAILIATTHCLTLLRDPVTQNGASKFEKSIGKYKYEEGYLKAPIDPFAFTND-LEFDLRYFLNIDHYETGGPILFYTGNEGSLEAFAENTGFMWDLAPELKAAVVFVEHRFYGKSQPFKNESYTDIRHLGYLSSQQALADFALSVQFFKNEKIKGAQKSAVIAFGGSYGGMLSAWFRIKYPHIVDGAIAASAPVFWFTDSNIPEDVYDF-IVTRAFLDAGCNRKAIEKGWIALDELAKSDSGRQYLNVLYKLDPKSKLENKDD-IGFLKQYIRESMEAMAMVNYPYPTSFLSSLPAWPVKEACKSASQPGKTQEESAEQLYKIVNLYYNYTGDKSTHCANAAKCDSAYGSLGDPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLAGGLAFGATSLPSASNIVFSNGYLDPWSGGG-YDHSDKVQGSVISVILKQGAHHYDLRGAHPQDTEEVKKVRAMETQAIKKWIKE 559          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Match: pcp-1 (Putative serine protease pcp-1 [Source:UniProtKB/Swiss-Prot;Acc:P34610])

HSP 1 Score: 207.223 bits (526), Expect = 5.628e-59
Identity = 156/456 (34.21%), Postives = 227/456 (49.78%), Query Frame = 3
Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXX-----TIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVL-MVGNVENCNYAFRVLTRAFKVKG-NEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIG-----LLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLS---TPINNPIQLLNAFYTGVQVFFNYTGQIR---------CLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWG---------QTLFWGKRLEAASNIVFSNGYLDPWSAGGV---YNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFAR 1541
            Y +  LDHFT+  D+  F M+ + +   +  G  I FY GNEG +E F   +G +++L    +  +IFAEHRFYG + PFG  SY    + GYL SEQALADYA+LLT LK       +     + VI+FGGSYGGML+AWFRQKYP+IV G+ A SAP++ M G   +      + +R +   G N   + N  NA   +   D      N + +F      K  +   G      L + +  M M +YPYPT FL P+PAWPVTV C  ++   T  ++   L+ A      +++NY              C        G D+ GW  Q C+E+ M MC  G ++  + N   K++          +    GW          +TL+ G  L  +SN++ + G+LDPWS GG     N++   + ++ I   AHH+DLR  +  D + +  AR
Sbjct:   46 YKNMKLDHFTW-GDTRTFDMRVMWNNTFYKPGGPIFFYTGNEGGLESFVTATGMMFDLAPMFNASIIFAEHRFYGQTQPFGNQSYASLANVGYLTSEQALADYAELLTELKRDNNQFKMTFPAATQVISFGGSYGGMLSAWFRQKYPHIVKGAWAGSAPLIYMNGGGVDPGAFDHITSRTYIDNGCNRFILANAWNATLNLSSTDAGRQWLNNNTVFKLDPRTKIRNQTDGWNLNAYLREAIEYMAMVDYPYPTGFLEPLPAWPVTVACGYMNANGTSFSDK-DLVKAVANAANIYYNYNRDPNFTYCIDFSICGDQGTGGLGGDELGWPWQECSEIIMAMCASGGSNDVFWNECGKDIYQTLQQGCVSIFKSMGWTPKNWNIDAVKTLY-GYDLSGSSNLILTQGHLDPWSGGGYKVDQNNAARGIYVLEIPGSAHHLDLRQPNTCDPNTVTNAR 498          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Match: pcp-1 (Putative serine protease pcp-1 [Source:UniProtKB/Swiss-Prot;Acc:P34610])

HSP 1 Score: 207.223 bits (526), Expect = 5.628e-59
Identity = 156/456 (34.21%), Postives = 227/456 (49.78%), Query Frame = 3
Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXX-----TIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVL-MVGNVENCNYAFRVLTRAFKVKG-NEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIG-----LLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLS---TPINNPIQLLNAFYTGVQVFFNYTGQIR---------CLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWG---------QTLFWGKRLEAASNIVFSNGYLDPWSAGGV---YNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFAR 1541
            Y +  LDHFT+  D+  F M+ + +   +  G  I FY GNEG +E F   +G +++L    +  +IFAEHRFYG + PFG  SY    + GYL SEQALADYA+LLT LK       +     + VI+FGGSYGGML+AWFRQKYP+IV G+ A SAP++ M G   +      + +R +   G N   + N  NA   +   D      N + +F      K  +   G      L + +  M M +YPYPT FL P+PAWPVTV C  ++   T  ++   L+ A      +++NY              C        G D+ GW  Q C+E+ M MC  G ++  + N   K++          +    GW          +TL+ G  L  +SN++ + G+LDPWS GG     N++   + ++ I   AHH+DLR  +  D + +  AR
Sbjct:   46 YKNMKLDHFTW-GDTRTFDMRVMWNNTFYKPGGPIFFYTGNEGGLESFVTATGMMFDLAPMFNASIIFAEHRFYGQTQPFGNQSYASLANVGYLTSEQALADYAELLTELKRDNNQFKMTFPAATQVISFGGSYGGMLSAWFRQKYPHIVKGAWAGSAPLIYMNGGGVDPGAFDHITSRTYIDNGCNRFILANAWNATLNLSSTDAGRQWLNNNTVFKLDPRTKIRNQTDGWNLNAYLREAIEYMAMVDYPYPTGFLEPLPAWPVTVACGYMNANGTSFSDK-DLVKAVANAANIYYNYNRDPNFTYCIDFSICGDQGTGGLGGDELGWPWQECSEIIMAMCASGGSNDVFWNECGKDIYQTLQQGCVSIFKSMGWTPKNWNIDAVKTLY-GYDLSGSSNLILTQGHLDPWSGGGYKVDQNNAARGIYVLEIPGSAHHLDLRQPNTCDPNTVTNAR 498          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Match: CG2493 (gene:FBgn0032864 transcript:FBtr0081363)

HSP 1 Score: 343.584 bits (880), Expect = 9.949e-112
Identity = 184/450 (40.89%), Postives = 271/450 (60.22%), Query Frame = 3
Query:  261 QYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA---ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGS--QHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMD-DPVGLTNLSKIFHTCKPLKSADSL---IGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
            ++KY+ K F   LDHF++  + A F ++YL +     K NA   I FY GNEG IELFA N+GF+WE  E+   +VIFAEHR+YG SLPFG  ++N S  +H  Y   EQ L DYA L+T+    +      PV+AFGGSYGGMLAAWFR KYP++V G++AASAPVL    + +C+  +R++T  F+   NE C  N+  +W + + +     G   +S  FH C  LK+ D L   +  + +   ++ M NYPY ++FL P+PA+PV   C  L    +    LL+A  + + V+ NYT   +CL  + +    DD+GWN+Q+C ++ MP+C++G   MF  + ++     + C+ +Y ++P+       + G+ LEAA+NI+FSNG LDPWS GGV  + N  V +I++  GAHH+DLR S P+D   +R AR  E   I +WI ++
Sbjct:   32 RFKYEIKEFQVPLDHFSFLIN-ATFNIRYLYNDSFVDKSNARTPIFFYTGNEGDIELFAQNTGFLWEQAERQRALVIFAEHRYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYAMLITF----LRNDRQMPVVAFGGSYGGMLAAWFRMKYPHLVNGALAASAPVLQFPGITDCDIFYRIVTSVFQNAYNENCTLNIAKSWKLFETLGASEAGKKQISDAFHLCNALKNDDDLKKFLDYVEEVYSNLAMVNYPYNSSFLAPLPAYPVRQVCYYLKELHSTDADLLHAMSSALAVYTNYTQSAKCLDIS-VNSNADDSGWNIQSCNQMVMPICSNGSETMFRTSSWNFKDYAEKCYKNYRLTPKPYDIILRYGGRNLEAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEGAHHLDLRHSDPADPPSVRDARDKEAAIIARWIQDF 475          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Match: CG2493 (gene:FBgn0032864 transcript:FBtr0332970)

HSP 1 Score: 343.584 bits (880), Expect = 9.949e-112
Identity = 184/450 (40.89%), Postives = 271/450 (60.22%), Query Frame = 3
Query:  261 QYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA---ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGS--QHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMD-DPVGLTNLSKIFHTCKPLKSADSL---IGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
            ++KY+ K F   LDHF++  + A F ++YL +     K NA   I FY GNEG IELFA N+GF+WE  E+   +VIFAEHR+YG SLPFG  ++N S  +H  Y   EQ L DYA L+T+    +      PV+AFGGSYGGMLAAWFR KYP++V G++AASAPVL    + +C+  +R++T  F+   NE C  N+  +W + + +     G   +S  FH C  LK+ D L   +  + +   ++ M NYPY ++FL P+PA+PV   C  L    +    LL+A  + + V+ NYT   +CL  + +    DD+GWN+Q+C ++ MP+C++G   MF  + ++     + C+ +Y ++P+       + G+ LEAA+NI+FSNG LDPWS GGV  + N  V +I++  GAHH+DLR S P+D   +R AR  E   I +WI ++
Sbjct:   32 RFKYEIKEFQVPLDHFSFLIN-ATFNIRYLYNDSFVDKSNARTPIFFYTGNEGDIELFAQNTGFLWEQAERQRALVIFAEHRYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYAMLITF----LRNDRQMPVVAFGGSYGGMLAAWFRMKYPHLVNGALAASAPVLQFPGITDCDIFYRIVTSVFQNAYNENCTLNIAKSWKLFETLGASEAGKKQISDAFHLCNALKNDDDLKKFLDYVEEVYSNLAMVNYPYNSSFLAPLPAYPVRQVCYYLKELHSTDADLLHAMSSALAVYTNYTQSAKCLDIS-VNSNADDSGWNIQSCNQMVMPICSNGSETMFRTSSWNFKDYAEKCYKNYRLTPKPYDIILRYGGRNLEAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEGAHHLDLRHSDPADPPSVRDARDKEAAIIARWIQDF 475          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Match: CG9953 (gene:FBgn0035726 transcript:FBtr0076898)

HSP 1 Score: 112.464 bits (280), Expect = 6.431e-26
Identity = 124/475 (26.11%), Postives = 198/475 (41.68%), Query Frame = 3
Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA--ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIK-KMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANY--PYPTNFLG---------PMPAWPVTVFCKP-LSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP---------------ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYE------------NRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +F   LDHF   +D   +Q +Y ++ + +   ++  +    G EG         G      E    + +  EHRFYG S P   +S   +++  YL+SEQAL D A  +T +K      +    IAFGGSY G LAAW R+KYP ++ GSI++S P+L    V+   Y F V+  +      E CVD V  +++ ++  +   +G  +L + F TC P+K  DS+         D+ MAN+      NF G         P     +   C   L+T    P+  L      V           CL                 +    G+    W  QTC E      +D   D F +            + F KN+N K   L    +          +G      +N+++ +G +DPW A G+  S+N ++  I I+  AH  ++     +D   +  AR    N I+K++++
Sbjct:   58 WFEQRLDHFK-SSDKRTWQQRYFVNADFYRNDSSAPVFLMIGGEGEASAKWMREGAWVHYAEHFGALCLQLEHRFYGKSHPTADLS---TENLHYLSSEQALEDLASFVTAMKVKFNLGDGQKWIAFGGSYPGSLAAWAREKYPELIYGSISSSGPLL--AEVDFKEY-FEVVKASLAAYKPE-CVDAVTRSFAQVEILLKHMIGQRSLDEKFKTCTPIK--DSIEN-------DLDMANFFENLAGNFAGVVQYNKDNSPHATITIDDICDVMLNTTAGPPVTRLGL----VNDMLLKESNTTCLDYKYDKMVADMKNVSWDSETAKGM--RQWTYQTCHEFGFYQTSDNPADTFGDRFGVDFFIRQCMDVFSKNMNAKFLKLVVSATND-------NYGALKPKTTNVLYVHGSIDPWHALGLVKSTNAALPTIYIEGTAHCANMYEPVKTDPPQLVAAR----NKILKFLAK 498          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Match: CG3734 (gene:FBgn0038700 transcript:FBtr0339152)

HSP 1 Score: 104.375 bits (259), Expect = 2.023e-23
Identity = 111/435 (25.52%), Postives = 184/435 (42.30%), Query Frame = 3
Query:  276 TKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSL-IGLLTDGLFDMGMANYPYPTNFLGPMP---AWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDD---NG-----WNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYG--VSPRWGWGQT----LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSD 1526
            T +    LDHF    ++  +QM+Y+++   +  G  +  Y G E  I       G ++++ ++ + ++ + EHR+YG S P   +S   +++  YLN  Q+LAD A  +  +K    G  +S VI  GGSY   +  WF++ YP++VAG  A+SAP+L    V    Y   +  ++ +  G  AC   + N  + ++ M        +  +   C+P      L +  L   + D+          F G +    A  +   C+ +    N+ I +       + VF    G+   L  + IT  L D   NG     W  QTC E      T G +   +  +F        C   YG   S  +   Q      F+G       N+  ++G LDPW A G+ + +    Q  +I   AH  D  S   SDT++
Sbjct:   47 TLWIEQKLDHFD-PEETRTWQMRYMLNDALYQSGAPLFIYLGGEWEISSGRITGGHLYDMAKEHNALLAYTEHRYYGQSKPLPDLS---NENIKYLNVNQSLADLAYFINTIKQNHEGLSDSKVIIVGGSYSATMVTWFKKLYPDLVAGGWASSAPLL--AKVNFVEYK-EITGQSIEQMGGSACYKRIENGIAEMETMIATKRGAEVKALLKLCEPFDVYSDLDVWTLFSEISDI----------FAGVVQTHNAGQIEGVCEKIMAGSNDLIGVAGYL---LDVFEESGGKCYDLSYDAITALLLDTNYNGNIMRQWIFQTCNEYGWYQ-TSGSSAQPFGTKFPVTYYTTMCADLYGSEYSNEFISNQVSITNQFFGGLFPNVENVYLTHGQLDPWRAMGIQDET----QATIIPEHAHCKDFNSISSSDTAE 456          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Match: CG3734 (gene:FBgn0038700 transcript:FBtr0083755)

HSP 1 Score: 104.375 bits (259), Expect = 2.023e-23
Identity = 111/435 (25.52%), Postives = 184/435 (42.30%), Query Frame = 3
Query:  276 TKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSL-IGLLTDGLFDMGMANYPYPTNFLGPMP---AWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDD---NG-----WNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYG--VSPRWGWGQT----LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSD 1526
            T +    LDHF    ++  +QM+Y+++   +  G  +  Y G E  I       G ++++ ++ + ++ + EHR+YG S P   +S   +++  YLN  Q+LAD A  +  +K    G  +S VI  GGSY   +  WF++ YP++VAG  A+SAP+L    V    Y   +  ++ +  G  AC   + N  + ++ M        +  +   C+P      L +  L   + D+          F G +    A  +   C+ +    N+ I +       + VF    G+   L  + IT  L D   NG     W  QTC E      T G +   +  +F        C   YG   S  +   Q      F+G       N+  ++G LDPW A G+ + +    Q  +I   AH  D  S   SDT++
Sbjct:   47 TLWIEQKLDHFD-PEETRTWQMRYMLNDALYQSGAPLFIYLGGEWEISSGRITGGHLYDMAKEHNALLAYTEHRYYGQSKPLPDLS---NENIKYLNVNQSLADLAYFINTIKQNHEGLSDSKVIIVGGSYSATMVTWFKKLYPDLVAGGWASSAPLL--AKVNFVEYK-EITGQSIEQMGGSACYKRIENGIAEMETMIATKRGAEVKALLKLCEPFDVYSDLDVWTLFSEISDI----------FAGVVQTHNAGQIEGVCEKIMAGSNDLIGVAGYL---LDVFEESGGKCYDLSYDAITALLLDTNYNGNIMRQWIFQTCNEYGWYQ-TSGSSAQPFGTKFPVTYYTTMCADLYGSEYSNEFISNQVSITNQFFGGLFPNVENVYLTHGQLDPWRAMGIQDET----QATIIPEHAHCKDFNSISSSDTAE 456          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Match: prcp (prolylcarboxypeptidase (angiotensinase C) [Source:ZFIN;Acc:ZDB-GENE-040718-447])

HSP 1 Score: 351.673 bits (901), Expect = 1.532e-114
Identity = 195/444 (43.92%), Postives = 272/444 (61.26%), Query Frame = 3
Query:  270 YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSADSLIGL---LTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPI---QLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            Y+T Y    +DHF +  ++  F+ +YL++ ++W K G  ILFY GNEG I  F NN+GF+W++ E+L  +++FAEHR+YG SLPFG+ SY+ +++  YL SEQ LAD+A L+  LK +  GAE S VIA GGSYGGMLAAW R KYPN V G++AASAP+     +  C   +RV+TR F + G+     ++ ++W+ I ++     GL  LS+ F  C PLKS + + G    L +   ++ M +YPY  +FL P+PAWPV V CK L    N  +   QLLN     V+V++NYTG   CL  +    G L   GW  Q+CTE+ MPMCTDGI DMF    +        C+  +GV PR  W +T++ G+ + A SNI+FSNG LDPW +GGV  S + S+  I+I  GAHH+DLR ++  D   +  AR LE     +WI
Sbjct:   47 YNTLYIDQQIDHFGFL-ENGTFKQRYLLNDQHWHKDGGPILFYTGNEGDITWFCNNTGFMWDVAEELGALLVFAEHRYYGESLPFGEESYSNAKYLNYLTSEQVLADFAVLIKALKKSQPGAEKSSVIAIGGSYGGMLAAWLRMKYPNAVVGALAASAPIWQF--IVPCGEFYRVVTRDFTISGSNC-SSSIRSSWAAIDRLSATGEGLQWLSQTFGLCGPLKSQEDVFGFKAWLQETWVNLAMVDYPYEADFLQPLPAWPVKVVCKNLQ--FNKGVSDKQLLNGVSQAVRVYYNYTGDAVCLNTSKTATGNLGFLGWFYQSCTEMVMPMCTDGINDMFEPQPWSFQAFSDECYNQFGVRPREDWAETVYGGRNIHAHSNIIFSNGNLDPWMSGGVTKSLSESLLAIMIDGGAHHLDLRYNNELDPQSVIKARSLEVQYFKQWI 484          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 310.842 bits (795), Expect = 9.388e-99
Identity = 192/474 (40.51%), Postives = 264/474 (55.70%), Query Frame = 3
Query:  198 GFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKG-NAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK---PLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            G T A  V++Y  +      +   +  KYF   LDHF Y +  +  +  +YLI+ + W KG   I FY GNEG I  FA NSGF+ EL      ++IFAEHR+YG SLPFGK S+   +  G L  EQALADYA ++T LK  + G +  PVI FGGSYGGML+ + R +YPNIVAG++AASAP+L    + +    F+ +T  F+ K N AC + V  A+  +  +        +   F  CK     K    L G L +    M M +YPY T+F+G MPA+PV V C+ +     N   L++A    V + +N TG++ C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F +   ++ C   +GV PR GW +T FWG  L  ASNI+FSNG LDPW+ GG+  S +PS+  I I  GAHH+DLR S+P+D   +  ARK E   I +W+
Sbjct:   17 GKTEARPVENYSNEITSHRDLSLDFKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEELGG-QTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIML----NGTDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDMFPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 483          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 309.686 bits (792), Expect = 3.050e-98
Identity = 187/450 (41.56%), Postives = 255/450 (56.67%), Query Frame = 3
Query:  270 YDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKG-NAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK---PLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +  KYF   LDHF Y +  +  +  +YLI+ + W KG   I FY GNEG I  FA NSGF+ EL      ++IFAEHR+YG SLPFGK S+   +  G L  EQALADYA ++T LK  + G +  PVI FGGSYGGML+ + R +YPNIVAG++AASAP+L    + +    F+ +T  F+ K N AC + V  A+  +  +        +   F  CK     K    L G L +    M M +YPY T+F+G MPA+PV V C+ +     N   L++A    V + +N TG++ C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F +   ++ C   +GV PR GW +T FWG  L  ASNI+FSNG LDPW+ GG+  S +PS+  I I  GAHH+DLR S+P+D   +  ARK E   I +W+
Sbjct:   50 FKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEELGG-QTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIML----NGTDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDMFPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 492          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 309.686 bits (792), Expect = 3.050e-98
Identity = 187/450 (41.56%), Postives = 255/450 (56.67%), Query Frame = 3
Query:  270 YDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKG-NAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK---PLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +  KYF   LDHF Y +  +  +  +YLI+ + W KG   I FY GNEG I  FA NSGF+ EL      ++IFAEHR+YG SLPFGK S+   +  G L  EQALADYA ++T LK  + G +  PVI FGGSYGGML+ + R +YPNIVAG++AASAP+L    + +    F+ +T  F+ K N AC + V  A+  +  +        +   F  CK     K    L G L +    M M +YPY T+F+G MPA+PV V C+ +     N   L++A    V + +N TG++ C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F +   ++ C   +GV PR GW +T FWG  L  ASNI+FSNG LDPW+ GG+  S +PS+  I I  GAHH+DLR S+P+D   +  ARK E   I +W+
Sbjct:   50 FKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEELGG-QTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIML----NGTDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDMFPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 492          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 309.686 bits (792), Expect = 3.050e-98
Identity = 187/450 (41.56%), Postives = 255/450 (56.67%), Query Frame = 3
Query:  270 YDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKG-NAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK---PLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +  KYF   LDHF Y +  +  +  +YLI+ + W KG   I FY GNEG I  FA NSGF+ EL      ++IFAEHR+YG SLPFGK S+   +  G L  EQALADYA ++T LK  + G +  PVI FGGSYGGML+ + R +YPNIVAG++AASAP+L    + +    F+ +T  F+ K N AC + V  A+  +  +        +   F  CK     K    L G L +    M M +YPY T+F+G MPA+PV V C+ +     N   L++A    V + +N TG++ C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F +   ++ C   +GV PR GW +T FWG  L  ASNI+FSNG LDPW+ GG+  S +PS+  I I  GAHH+DLR S+P+D   +  ARK E   I +W+
Sbjct:   50 FKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEELGG-QTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIML----NGTDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDMFPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 492          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:780095])

HSP 1 Score: 406.757 bits (1044), Expect = 9.544e-136
Identity = 213/473 (45.03%), Postives = 299/473 (63.21%), Query Frame = 3
Query:  180 LLLMISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            LLL+ +  ++  S +    +++  +     Y+T YF+  +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:   20 LLLLSAAHSVRLSRQFGSAQQYGSSNPGPSYETYYFTQQVDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 490          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:780095])

HSP 1 Score: 396.741 bits (1018), Expect = 1.512e-132
Identity = 205/436 (47.02%), Postives = 282/436 (64.68%), Query Frame = 3
Query:  297 LDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWK 1586
            +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++++
Sbjct:    5 VDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQFE 438          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:780095])

HSP 1 Score: 396.741 bits (1018), Expect = 2.032e-132
Identity = 205/434 (47.24%), Postives = 280/434 (64.52%), Query Frame = 3
Query:  297 LDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:   19 VDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 450          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:780095])

HSP 1 Score: 396.741 bits (1018), Expect = 2.391e-132
Identity = 205/434 (47.24%), Postives = 280/434 (64.52%), Query Frame = 3
Query:  297 LDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:   21 VDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 452          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:780095])

HSP 1 Score: 395.971 bits (1016), Expect = 2.829e-132
Identity = 205/434 (47.24%), Postives = 280/434 (64.52%), Query Frame = 3
Query:  297 LDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:    5 VDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAD 436          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Mouse
Match: Prcp (prolylcarboxypeptidase (angiotensinase C) [Source:MGI Symbol;Acc:MGI:1919711])

HSP 1 Score: 371.318 bits (952), Expect = 3.903e-122
Identity = 195/444 (43.92%), Postives = 275/444 (61.94%), Query Frame = 3
Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            V  KY   YF   +DHF +  D   F+ +YL++ ++W + G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG+ S+  SQH  +L SEQALAD+A+L+ +L+ TI GA+  PVIA GGSYGGMLAAWFR KYP+IV G++AASAP+  +  +  C    +++T  F+ K    C +++  +W+VI K+     GL +L+ I H C PL S    +L G + +   ++ M NYPY  NFL P+PAWP+   C+ L  P  +   LL   +  + V++NY+GQ  CL  +   T  L   GW+ Q CTE+ MP CT+GI DMF    +D      +C   +GV PR  W  T++ GK + + SNI+FSNG LDPWS GGV      ++  I I +GAHH+DLR+ +  D S +  +R LE   + KWI
Sbjct:   42 VARKYSVLYFEQKVDHFGFA-DMRTFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIWQLDGMVPCGEFMKIVTNDFR-KSGPYCSESIRKSWNVIDKLSGSGSGLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSDTVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWI 483          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Mouse
Match: Prcp (prolylcarboxypeptidase (angiotensinase C) [Source:MGI Symbol;Acc:MGI:1919711])

HSP 1 Score: 342.813 bits (878), Expect = 1.628e-111
Identity = 187/443 (42.21%), Postives = 257/443 (58.01%), Query Frame = 3
Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            V  KY   YF   +DHF +  D   F+ +YL++ ++W + G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG+ S+  SQH  +L SEQALAD+A+L+ +L+ TI GA+  PVIA GGSYGGMLAAWFR KYP+IV G++AASAP+  +  +  C                                     GL +L+ I H C PL S    +L G + +   ++ M NYPY  NFL P+PAWP+   C+ L  P  +   LL   +  + V++NY+GQ  CL  +   T  L   GW+ Q CTE+ MP CT+GI DMF    +D      +C   +GV PR  W  T++ GK + + SNI+FSNG LDPWS GGV      ++  I I +GAHH+DLR+ +  D S +  +R LE   + KWI
Sbjct:   42 VARKYSVLYFEQKVDHFGFA-DMRTFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIWQLDGMVPCG-----------------------------------SGLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSDTVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWI 448          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Mouse
Match: Dpp7 (dipeptidylpeptidase 7 [Source:MGI Symbol;Acc:MGI:1933213])

HSP 1 Score: 278.1 bits (710), Expect = 6.986e-86
Identity = 181/457 (39.61%), Postives = 259/457 (56.67%), Query Frame = 3
Query:  252 NIVQYKYDTKYFSTYLDHFTYKNDSAK-FQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPL---KSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPIT--PGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWIS 1577
             ++   +   YF  Y+DHF +++   K F  ++L+S + W  G   I FY GNEG I  FANNSGF+ EL  Q   +++FAEHR+YG SLPFG  S     +   L  EQALAD+A LL  L+  + G  ++P IAFGGSYGGML+A+ R KYP++VAG++AASAPV+ V  + +    FR +T  F  + +  C   V +A+  IK +        +S+ F TC+ L   K    L G   +    + M +YPYPT+FLGP+PA PV V C+ L     N  Q +        + +N +G   C          A+P     G D   W+ Q CTE+ +   ++ +TDMF E  F + +  + C  ++GV PR  W QT FWG  L+AASNI+FSNG LDPW+ GG+ ++ + SV  + I+ GAHH+DLR+S+  D   +   RKLE   I +W++
Sbjct:   35 RVLDPDFHENYFEQYMDHFNFESFGNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSFANNSGFMVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRG-YTQLLTVEQALADFAVLLQALRQDL-GVHDAPTIAFGGSYGGMLSAYMRMKYPHLVAGALAASAPVVAVAGLGDSYQFFRDVTADFYGQ-SPKCAQAVRDAFQQIKDLFLQGAYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCQRLL----NEGQRIMGLRALAGLVYNSSGTEPCYDIYRLYQSCADPTGCGTGSDARAWDYQACTEINLTFDSNNVTDMFPEIPFSEELRQQYCLDTWGVWPRQDWLQTSFWGGDLKAASNIIFSNGDLDPWAGGGIQSNLSTSVIAVTIQGGAHHLDLRASNSEDPPSVVEVRKLESTLIREWVA 484          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Mouse
Match: Prss16 (protease, serine 16 (thymus) [Source:MGI Symbol;Acc:MGI:1859181])

HSP 1 Score: 113.235 bits (282), Expect = 4.513e-26
Identity = 119/459 (25.93%), Postives = 188/459 (40.96%), Query Frame = 3
Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILF-YCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAF-RVLTRAFKVKGNEACVDNVHNAWSVIKKM--DDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLN--AFYTGVQVFFNYTGQIRCLP------------ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSP---RWGWGQT-LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            +    LD F   +D   F  +Y ++ ++    +  +F + G EGS+   +  +G    L      +VI  EHRFYG S+P G +         YL+S  ALAD A     L   +  + +SP I FGGSY G LA W R K+P++V  ++A+SAP+  V +    N    R LT+   + G+  C+     A++ ++++    P     L +    C  L   +    LL   L  +      Y      P+    V   C  L     N  +          VQ+     GQ +CL               P   G+ D  W  QTCTE    +  +G+   F +         + C   +G+SP        QT  ++G +   A+ ++F NG  DPW    V      S   +LI + +H  D+    PSD+  +R  R+     +  W+ + K S
Sbjct:   60 WLEQPLDPFN-ASDRRTFLQRYWVNDQHRTGQDVPVFLHIGGEGSLGPGSVMAGHPAALAPAWGALVISLEHRFYGLSMPAGGLDLA---LLRYLSSRHALADVASARQALSGLLNVSSSSPWICFGGSYAGSLATWARLKFPHLVFAAVASSAPLSAVVDFSAYNQVVARSLTQ-VAIGGSLECLAAASTAFTEVERLLRAGPAAQAVLREELGACGSLDLTEDQAELL-GALQALVGGTVQYDGQAGAPL---SVRQLCGLLLGKWGNRSRSTPYLGLRRAVQIVLRSMGQ-KCLSFSRAETVAQLSNTEPQVSGVGDRQWLYQTCTEFGFYVTCEGLQCPFSQLP-ALPFQLELCEQVFGLSPASVAQAVAQTNSYYGGQSPGATQVLFVNGDTDPWHVLSVTQDLGLSEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKISQQLQDWLKDIKKS 507          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Mouse
Match: Prss16 (protease, serine 16 (thymus) [Source:MGI Symbol;Acc:MGI:1859181])

HSP 1 Score: 57.7658 bits (138), Expect = 2.261e-9
Identity = 40/151 (26.49%), Postives = 64/151 (42.38%), Query Frame = 3
Query: 1161 NPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENR---FDKNVNDKNCHLSYGVSPR---WGWGQT-LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
             P   G+ D  W  QTCTE    +  +G+   F +     F   +    C   +G+SP        QT  ++G +   A+ ++F NG  DPW    V      S   +LI + +H  D+    PSD+  +R  R+     +  W+ + K S
Sbjct:   21 EPQVSGVGDRQWLYQTCTEFGFYVTCEGLQCPFSQLPALPFQLEL----CEQVFGLSPASVAQAVAQTNSYYGGQSPGATQVLFVNGDTDPWHVLSVTQDLGLSEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKISQQLQDWLKDIKKS 167          
BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Match: sp|Q7TMR0|PCP_MOUSE (Lysosomal Pro-X carboxypeptidase OS=Mus musculus OX=10090 GN=Prcp PE=1 SV=2)

HSP 1 Score: 371.318 bits (952), Expect = 2.730e-121
Identity = 195/444 (43.92%), Postives = 275/444 (61.94%), Query Frame = 3
Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            V  KY   YF   +DHF +  D   F+ +YL++ ++W + G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG+ S+  SQH  +L SEQALAD+A+L+ +L+ TI GA+  PVIA GGSYGGMLAAWFR KYP+IV G++AASAP+  +  +  C    +++T  F+ K    C +++  +W+VI K+     GL +L+ I H C PL S    +L G + +   ++ M NYPY  NFL P+PAWP+   C+ L  P  +   LL   +  + V++NY+GQ  CL  +   T  L   GW+ Q CTE+ MP CT+GI DMF    +D      +C   +GV PR  W  T++ GK + + SNI+FSNG LDPWS GGV      ++  I I +GAHH+DLR+ +  D S +  +R LE   + KWI
Sbjct:   42 VARKYSVLYFEQKVDHFGFA-DMRTFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIWQLDGMVPCGEFMKIVTNDFR-KSGPYCSESIRKSWNVIDKLSGSGSGLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSDTVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWI 483          
BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Match: sp|P42785|PCP_HUMAN (Lysosomal Pro-X carboxypeptidase OS=Homo sapiens OX=9606 GN=PRCP PE=1 SV=1)

HSP 1 Score: 365.54 bits (937), Expect = 5.253e-119
Identity = 191/450 (42.44%), Postives = 275/450 (61.11%), Query Frame = 3
Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            V   Y   YF   +DHF + N    F  +YL++ + W K G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG  S+  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++H +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NFL P+PAWP+ V C+ L  P  +   LL   +  + V++NY+GQ++CL  +   T  L   GW+ Q CTE+ MP CT+G+ DMF  + ++      +C   +GV PR  W  T++ GK + + +NIVFSNG LDPWS GGV      ++  + I  GAHH+DLR+ +  D   +  AR LE   +  WI ++  S
Sbjct:   44 VAKNYSVLYFQQKVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDS 491          
BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Match: sp|Q5RBU7|PCP_PONAB (Lysosomal Pro-X carboxypeptidase OS=Pongo abelii OX=9601 GN=PRCP PE=2 SV=1)

HSP 1 Score: 362.844 bits (930), Expect = 5.666e-118
Identity = 189/450 (42.00%), Postives = 275/450 (61.11%), Query Frame = 3
Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            V   Y   YF   +DHF + N    F  +YL++ + W K G +ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG  ++  S+H  +L SEQALAD+A+L+ +LK TI GAEN PVIA GGSYGGMLAAWFR KYP++V G++AASAP+    ++  C    +++T  F+  G   C +++  +W  I ++ +   GL  L+   H C PL S D   L   +++   ++ M +YPY +NFL P+PAWP+ V C+ L  P  +   LL   +  + V++NY+GQ++CL  +   T  L   GW+ Q CTE+ MP CT+G+ DMF  + ++      +C   +GV PR  W  T++ GK + + +NIVFSNG LDPWS GGV      ++  + I  GAHH+DLR+ +  D + +  AR LE   +  WI ++  S
Sbjct:   44 VAKNYSVLYFQQKVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNTFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIRRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPTSVLLARSLEVRHMKNWIRDFYDS 491          
BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Match: sp|Q2TA14|PCP_BOVIN (Lysosomal Pro-X carboxypeptidase OS=Bos taurus OX=9913 GN=PRCP PE=2 SV=1)

HSP 1 Score: 351.673 bits (901), Expect = 1.474e-113
Identity = 190/454 (41.85%), Postives = 276/454 (60.79%), Query Frame = 3
Query:  258 VQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPL-KSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCK-------PLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCL-PANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +  KY  +Y    +DHF +  D   F+ +YLI+   W + G +ILFY GNEG I  F NN+GF+W++ E++  M++FAEHR+YG SLPFG  S++ S+H  +L +EQALAD+A L+ YLK TI GA N  VIA GGSYGGMLAAWFR KYP++V G++A+SAP+    ++  C+   +++T  F   G   C +++  +W  I ++     GL  LS+  H C PL KS D   L   +++   ++ M +YPY +NFL P+PAWPV V C+       P +  + N  Q LN       V++NY+GQ +CL  +   T  L   GW+ Q CTE+ MP C+DG+ DMF  + ++      +C   +GV PR  W  T++ GK + + +NI+FSNG LDPWS GGV      ++  I+I NGAHH+DLR+S+  D   ++  R LE   + +WIS+
Sbjct:   46 ITLKYSIRYIQQKVDHFGFNIDRT-FKQRYLIADNYWKEDGGSILFYTGNEGDIIWFCNNTGFMWDIAEEMKAMLVFAEHRYYGESLPFGADSFSDSRHLNFLTTEQALADFAKLIRYLKRTIPGARNQHVIALGGSYGGMLAAWFRMKYPHLVVGALASSAPIWQFNDLVPCDIFMKIVTTDFSQSGPN-CSESIRRSWDAINRLAKKGTGLRWLSEALHLCTPLTKSQDVQRLKDWISETWVNVAMVDYPYESNFLQPLPAWPVKVVCQYFKYSNVPDTVMVQNIFQALN-------VYYNYSGQAKCLNVSETATSSLGVLGWSYQACTEMVMPTCSDGVDDMFEPHSWNMKEYSDDCFKQWGVRPRPSWIPTMYGGKNISSHTNIIFSNGELDPWSGGGVTKDITDTLLAIVIPNGAHHLDLRASNALDPVSVQLTRSLEVKYMKQWISD 490          
BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Match: sp|Q9UHL4|DPP2_HUMAN (Dipeptidyl peptidase 2 OS=Homo sapiens OX=9606 GN=DPP7 PE=1 SV=3)

HSP 1 Score: 308.531 bits (789), Expect = 6.236e-97
Identity = 182/450 (40.44%), Postives = 255/450 (56.67%), Query Frame = 3
Query:  270 YDTKYFSTYLDHFTYKNDSAK-FQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLL---TDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGL--DDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +  ++F   LDHF ++    K F  ++L+S   WV+G   I FY GNEG +  FANNS FV EL  +   +++FAEHR+YG SLPFG  S     H   L  EQALAD+A+LL  L+  + GA+++P IAFGGSYGGML+A+ R KYP++VAG++AASAPVL V  + + N  FR +T  F+ + +  C   V  A+  IK +        +   F TC+PL     L  L     +    + M +YPYPT+FLGP+PA PV V C  L +      Q +        + +N +G   C          A+P   G   D   W+ Q CTE+ +   ++ +TDMF +  F   +  + C  ++GV PR  W  T FWG  L AASNI+FSNG LDPW+ GG+  + + SV  + I+ GAHH+DLR+SHP D + +  ARKLE   I +W+
Sbjct:   31 FQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQ-RGHTELLTVEQALADFAELLRALRRDL-GAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQ-SPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA----QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWV 473          
BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Match: Q08D72 (Prolylcarboxypeptidase (Angiotensinase C) OS=Xenopus tropicalis OX=8364 GN=prcp PE=2 SV=1)

HSP 1 Score: 406.757 bits (1044), Expect = 1.497e-132
Identity = 213/473 (45.03%), Postives = 299/473 (63.21%), Query Frame = 3
Query:  180 LLLMISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            LLL+ +  ++  S +    +++  +     Y+T YF+  +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:   23 LLLLSAAHSVRLSRQFGSAQQYGSSNPGPSYETYYFTQQVDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 493          
BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Match: A0A5G3HCF4 (Uncharacterized protein OS=Xenopus tropicalis OX=8364 GN=prcp PE=4 SV=1)

HSP 1 Score: 406.757 bits (1044), Expect = 1.499e-132
Identity = 213/473 (45.03%), Postives = 299/473 (63.21%), Query Frame = 3
Query:  180 LLLMISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLI---GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            LLL+ +  ++  S +    +++  +     Y+T YF+  +DHF +  D A F+ +YL+S   W K G  ILFY GNEG I LF NN+GF+W++ E++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA+NSPVIA GGSYGGMLAAWFR KYP++V G+IA+SAP+    ++  CN  ++V+T  FK K    C ++V N+W+ I +M +   GL  LS  FH C PLKS + +    G L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG   CL  +    G L D GW+ Q CTE+ MP C+DG++DMF    +D       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  +LI  GAHH+DLRS++  D   +  AR LE   + KWI++
Sbjct:   20 LLLLSAAHSVRLSRQFGSAQQYGSSNPGPSYETYYFTQQVDHFGFYED-ATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFK-KSGPGCSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGDKDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQAFSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 490          
BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Match: A0A1L8HJS7 (Uncharacterized protein OS=Xenopus laevis OX=8355 GN=XELAEV_18014029mg PE=4 SV=1)

HSP 1 Score: 404.06 bits (1037), Expect = 2.280e-131
Identity = 209/473 (44.19%), Postives = 301/473 (63.64%), Query Frame = 3
Query:  180 LLLMISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVK-GNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKSADSLIGL---LTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            LL++++  + + S +    +++  +     Y T YF+  +DHF +  D A F+ +YL+S  +W K G  ILFY GNEG I  F NN+GF+W++ +++  M++FAEHR+YG S+PFG ++++  +H  YL SEQALAD+A LL Y KAT  GA++SPVIA GGSYGGMLAAWFR KYP++V G++A+SAP+    ++  CN  ++++T  FK K    C ++V N+W  I +M +   GL  LSK FH C PLK+ + ++G    L++    + M +YPYP +FL P+PAWP+ V CK L  P +    LL   +  V V++NYTG  +CL  +    G L D GW+ Q CTE+ MP C+DG+TDMF    +D     + C+  +GV PR  W  T++ GK + + SNI+FSNG LDPWSAGGV  S + S+  ILI  GAHH+DLRS++  D   +  AR LE   + KWI +
Sbjct:   23 LLMILAAHSFSLSRQVGSGQQYGSSTPGPNYQTYYFTQQVDHFGFFED-ATFKQRYLVSAAHWKKPGGPILFYTGNEGDITWFCNNTGFMWDVAKEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQDSPVIALGGSYGGMLAAWFRMKYPDVVVGAVASSAPIWQFEDLVPCNEYYQIVTNDFK-KSGPGCSESVRNSWEAINRMAETSDGLQWLSKAFHLCCPLKNKEDVVGFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKNPKSGDKDLLQDIFQAVNVYYNYTGDTQCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVTDMFEPQSWDFQAYSEECNKQWGVRPRGSWITTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLVAILIPEGAHHLDLRSNNDCDPKSVLLARGLEVEYMKKWIEQ 493          
BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Match: A0A1V4JRH3 (Lysosomal Pro-X carboxypeptidase OS=Patagioenas fasciata monilis OX=372326 GN=PRCP PE=4 SV=1)

HSP 1 Score: 400.593 bits (1028), Expect = 2.167e-130
Identity = 207/441 (46.94%), Postives = 288/441 (65.31%), Query Frame = 3
Query:  270 YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSADSLIGL---LTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            Y  +YF   +DHF + +D+  FQ +YLI+ ++W K N  ILFY GNEG +  F+NN+GF+W++ ++L+ MV+FAEHR+YG SLPFG  SY+ S+   YL SEQALAD+A L+ +LK+TIAGA  SPVIA GGSYGGMLAAWFR KYP++V G++AASAP+   G++  C   F ++T+ FK  G   C +++ N+WS I ++     GL  LSK FH C PLK+   +  L   L+D   ++ M NYPY  +FL P+PAWP+   CK L  P  +   LL   +  + +++NY+GQI C   A   T  L   GWN QTCTE+ MP+CTDG+ DMF   ++D     + C+  +GV PR  W  +++ GK + + SNI+FSNG LDPWSAGGV  + + S+  I+I  GAHH+DLR  +PSD   ++ AR LE   + +WI
Sbjct:   33 YLIRYFQQQVDHFGF-DDNLTFQQRYLIADQHWKKNNGPILFYTGNEGDVTWFSNNTGFMWDVAQELNAMVVFAEHRYYGESLPFGNESYSDSKRLNYLTSEQALADFAVLIEHLKSTIAGARYSPVIAIGGSYGGMLAAWFRMKYPHLVVGALAASAPIWQFGDLVPCGAFFSIVTKDFKRSGT-GCAESIRNSWSAIDRLSSTDEGLLWLSKTFHLCSPLKNLQDVAVLKRGLSDTWINLAMMNYPYKADFLEPLPAWPIEEVCKFLKDPSLSDRLLLQNVFQAINIYYNYSGQILCFDMAETATKSLGHLGWNYQTCTEMVMPLCTDGVNDMFEPQKWDLKARSEECYKLWGVRPRPSWIISMYGGKNIHSHSNIIFSNGGLDPWSAGGVTRNISHSLVAIMIPEGAHHLDLRGRNPSDPKSVQQARDLELCYMKQWI 471          
BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Match: A0A564Z3X4 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS12005 PE=4 SV=1)

HSP 1 Score: 400.208 bits (1027), Expect = 4.138e-130
Identity = 212/466 (45.49%), Postives = 285/466 (61.16%), Query Frame = 3
Query:  207 IAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKM-DDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQ-----LLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYN-SSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
            I+F++  ++I+        + Y+ K F+ +LDHF++   S KF + YLISTE W  G  ILFY GNEGSIE FA N+G ++EL E L+  VIFAEHR+YG+SLPFG  S+N  +HFGYL +EQALADYA LLT  K       NSPVI+FGGSYGGML AWFRQ YPN+V G +AASAP+ +   + +C   ++V TRA++  G   C   +   WS+I ++   P GL +LS  F TC+   S D + G + D L  + M NYPY T+FLG +PAWPV  FCK +   +N PI+      +  F       +NY  + +CL     +  LD  GW +QTC E+  P+C+DG TDMF    +D      +C   +GV PR  W    +W K +   + ++FSNG LDPWSA GV N +S P   ++ I  GAHH+DLR SHP+DT ++R AR L ++ I  WI EW
Sbjct:   15 ISFAILSHRIRPSKKFQSPFSYEKKSFTEFLDHFSF-GPSHKFNITYLISTEKWKPGGPILFYTGNEGSIEHFARNTGLIFELAENLTGAVIFAEHRYYGTSLPFGNQSFNDRRHFGYLIAEQALADYAKLLTDFKCANHQFANSPVISFGGSYGGMLTAWFRQAYPNVVTGGLAASAPIWLFPGMCDCRGFYQVTTRAYQQGGGSQCTSTIREIWSLIDEIAKKPHGLDDLSGAFKTCELFSSGDFVSGFVEDYLVTLAMGNYPYSTSFLGELPAWPVKEFCKAI---VNCPIEGKLPPQVEKFACAFFSLYNYKQEDKCLSFASGSENLDSRGWELQTCMEMTNPICSDGKTDMFRPRGWDPIEFSNSCQDRFGVQPRMDWAGLQWWAKDIITDTRLIFSNGDLDPWSAFGVLNETSAPGATVVRIGRGAHHLDLRGSHPNDTEEVRAARGLIRDKIASWIEEW 476          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Cavefish
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:103038921])

HSP 1 Score: 347.436 bits (890), Expect = 8.881e-113
Identity = 192/459 (41.83%), Postives = 274/459 (59.69%), Query Frame = 3
Query:  228 YKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP-VGLTNLSKIFHTCKPLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNP-IQLLNAFYTGVQVFFNYTGQIRCLPANPITPG-LDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYN--SSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISE 1580
            +++ + +       Y T Y    +DHF +  ++  F+ +YL++  +W K N+ ILFY GNEG I  F NN+GF+W++ E+L  M++FAEHR+YG SLPFG  SY+ +++  YL SEQALAD+A L+  LK T  GA+NSPVIA GGSYGGML+AW R KYP+ V G++AASAP+    ++  C   ++++T+ F + G   C +N+  +W  I  +     GL  LS+ F  C PLK  D     G L +   ++ M +YPY  NFL P+P WP+ V C  LS   + P  +LL+     V V++NYTG   CL  +    G L   GW  Q+CTE+ MPMCTDGI DMF    ++       C+  +GV PR  W  T++ GK + + SNI+FSNG LDPW +GGV      + S+  I+I +GAHH+DLR ++  D   +  AR +E     KWI +
Sbjct:   39 HRVTRSLPQQRPVSYTTLYLDQQIDHFGFL-ENGTFKQRYLLNDLHWHKDNSPILFYTGNEGDITWFCNNTGFMWDIAEELGAMLVFAEHRYYGESLPFGDESYSNAKYLNYLTSEQALADFAVLIENLKKTYPGAQNSPVIAIGGSYGGMLSAWLRMKYPSAVVGALAASAPIWQFTDMVPCGDFYKIVTQDFAISGFN-CSNNIRRSWMAINNVSSTDEGLQWLSEEFRLCSPLKEEDVSGFKGWLQETWVNLAMVDYPYEANFLQPLPRWPIKVVCSYLSFVTDVPDKELLHGISQAVNVYYNYTGNAECLNISLTATGNLGIRGWFYQSCTEMVMPMCTDGIQDMFEPQPWNFQAFSDECYDLFGVRPREHWADTVYGGKNICSHSNIIFSNGRLDPWMSGGVTRLCGVSDSLVAIVIPDGAHHLDLRYNNEYDPETVIRARAVEVQYFKKWIKQ 495          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Cavefish
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 273.092 bits (697), Expect = 1.214e-84
Identity = 175/451 (38.80%), Postives = 252/451 (55.88%), Query Frame = 3
Query:  267 KYDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK-PLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            ++  KYF+  LDHF Y +  +  +  +YLI+ + W KG+  I FY GNEG I  FA NSGFV EL  + + +VIFAEH      +P          + G L  EQALADYA ++T LK  +  AE  PVI FGGSYGGML+ + R +YPNIV G++AASAP+L    + +    FR +T  F+   +  C D+V +A+  ++ +        +   F  CK P  S D   L G L +    + M +YPY T+F+  MPA+PV V C+ +     N  ++L+A    V + +N TG+  C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F +++ ++ C   + V PR GW +T +WG  L  ASNI+FSNG LDPW+ GG+  S + S+  I I  GAHH+DLR+S+P+D   +  AR+ E   I +W+
Sbjct:   25 QFKEKYFTQILDHFNYNSLGNGTYPQRYLITDQYWKKGSGPIFFYTGNEGDIWDFALNSGFVLELAVEQAALVIFAEHD-KSFIIP----------NVGLLTVEQALADYAVMITDLKKELR-AEKCPVIVFGGSYGGMLSVYMRVRYPNIVTGALAASAPILSTAGMGDSGQFFRDVTADFE-NCSPVCKDSVRSAFQKLQTLAQQEDYAGIQSAFSLCKTPSSSKDIHQLNGFLRNAFTLLAMMDYPYKTSFMSVMPAFPVKVACETML----NGTEVLSALRDTVGIVYNSTGEHACYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDMFPPMPFTESMREEYCARRWAVVPRPGWLKTQYWGDALSTASNIIFSNGDLDPWANGGIRKSLSDSLIAINIPEGAHHLDLRASNPADPDSVIKARQTEAKLIAQWV 458          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Cavefish
Match: ENSAMXT00000015346.2 (serine protease 16 [Source:NCBI gene;Acc:103045980])

HSP 1 Score: 113.235 bits (282), Expect = 4.063e-26
Identity = 119/451 (26.39%), Postives = 196/451 (43.46%), Query Frame = 3
Query:  297 LDHFTYKNDSAKFQMKYLISTENWVKGNAILF-YCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAF---KVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFD--MGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQV--FFNYTGQIRCLPANPITPGLDDN----------GWNVQTCTELPM-PMCTDGITDMFYENRFDKNVNDKNCHLSYGVS----PRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSA-GGVYNSSNPSV-QIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            LDHF  +N +  F  ++ I+   W   +  +F Y G EG +  F+  +G    + +Q   +++  EHRFYG S+  G +     Q+  YL+S+QALAD A    ++         +  I+FGGSY G L+AWFR K+P++V G++A+SAPV     ++  +Y   V+ R+     V G+E CV  V  A++ ++        T + K F  C+  KS +    LL   L D  MG   Y      L       +   C  ++      ++   A+   V++   +    +  CL  +     LD N           W  QTCTE      C D      +    +     + C L + +     P       L++G        +++ NG  DPW A   V N +N    + ILI + AH  D+  +   D + +  AR+  ++ +  W+
Sbjct:   59 LDHFNRRN-TRTFPQRFFINEAYWKHPHGPVFLYIGGEGPLSEFSVLAGHHVTMAKQQGALLVALEHRFYGRSIIPGGLE---PQNLQYLSSQQALADLAAFHQHISQKYNLTYRNIWISFGGSYAGALSAWFRGKFPHLVYGAVASSAPV--QAKLDFSSYT-TVVGRSLMDESVGGSEKCVKAVWEAFAAVEAALLRGEETQVGKDFSCCETPKSLEDQTELLR-SLADIFMGTVQYNEEVGLL------TIARLCSIMTNQSKAYVEGKEAYDRLVRLAAIYRTMEKETCLEVSYEKSILDLNTTTHVSSGYRQWFYQTCTEFGFYQTCEDATCP--FSRMMNLQTEIQLCPLLFSIPQHTLPSNIAFTNLYYGGDQPQTQRVLYVNGDTDPWMALSVVRNGTNKDKHRAILIHSSAHCADMNPTRARDRASLLQARQEIESLVEAWL 493          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Cavefish
Match: prss16 (putative serine protease K12H4.7 [Source:NCBI gene;Acc:103026864])

HSP 1 Score: 102.834 bits (255), Expect = 8.709e-23
Identity = 118/439 (26.88%), Postives = 180/439 (41.00%), Query Frame = 3
Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLK---SADS--LIGLLTDGLFDMGMANYPYPTNFLGPMPA-WPVTVFCKP-LSTPINNPIQLLNAFYTGVQVFF-------NYTGQIRCLPANPITPGLDDNG--WNVQTCTELPMPMCTDGITDMF------YENRFDKNVNDKNCHLSYGVSPRWGWGQT-LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDI 1529
            +F   LDHF    DS  ++ +Y I+   +  G  +    G EG         G      E+   + +  EHRFYG S P   +S    +   +L+S QALAD A   +    T     N   +AFGGSY G LAAWFR KYP++V  S+A SAPV    N         V+ ++ + +  +  V     + +++ ++ DP    N++K F  C  L+     DS  L+  L     D+   N      F G +     + V C   L + +  P     A    +Q  F        Y+  +R +     T      G  W  QTC E      TD     F      Y  R   ++ + N  ++  V       QT   +G     ++ IVF NG +DPW A GV ++    +  + IK  AH  ++   +P+   D+
Sbjct:   54 WFIQRLDHFN-GADSRVWKQRYFINDRFYKPGGPVFLMIGGEGPANPAWMQYGTWLNYAEKFGALCLLLEHRFYGKSHPTEDLSV---ESLRFLSSRQALADLAHFRSVTAETRKLTSNK-WVAFGGSYPGSLAAWFRLKYPHLVHASVATSAPVYATVNFTE---YLEVVQKSLEAENPQCPVLVKKASDTLMARLKDPKTYDNITKDFRLCSKLEIQSDMDSAYLLETLAGNFMDVVQYNEDNRA-FEGVLGTNITIKVLCDVMLDSLLGEPYDRYAAVARLLQKTFLQSCTDAQYSQYVREMSNTSWTGPAASGGRQWVYQTCAEFGFYQSTDSQNQPFGGFPLKYHLRQCNDIYNLNSSVADAVQ------QTNEEYGGYDIRSTRIVFPNGSIDPWHALGVISNITDELPAVFIKGTAHCANM---YPARAEDL 474          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Sea Lamprey
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 144.05 bits (362), Expect = 2.196e-39
Identity = 89/268 (33.21%), Postives = 135/268 (50.37%), Query Frame = 3
Query:  813 KGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCK-PLKSAD--SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGL--DDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWIS 1577
            K N  C D V   +  +KK+ D      +++    C+ P  +AD   + G   +    + M +YPY  +F+G +PA PV V C  L     N    L+     V +F+N +G  +CL         A+P   GL  D   W+ Q CTE+ +   T+ ++DMF    +      + C   +GV PR  W  T +WGK + ++SNI+FSNG LDPW  GG  +    +V + +I  GAHH+DLR S+P+D   +  ARKLE   +  W++
Sbjct:    4 KYNPKCPDIVRAGFIELKKLADKQEWAQIAQRMRLCQAPSSAADVRHMYGWARNTFTYLAMLDYPYAASFMGSLPANPVNVACDLLL----NSKDPLDGLMQAVALFYNTSGTAKCLDPAAEFIECADPTGCGLGPDSLAWDYQACTEINLLCSTNNVSDMFPALPYTAAARREYCAKRWGVVPRETWLATQYWGKDVNSSSNIIFSNGNLDPWGNGGFQHDVGGNVAVKVI-GGAHHLDLRYSNPADPESVVTARKLESALLHTWLA 266          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005355.1 (pep scaffold:Pmarinus_7.0:GL477796:147175:163357:-1 gene:ENSPMAG00000004846.1 transcript:ENSPMAT00000005355.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 127.487 bits (319), Expect = 1.598e-31
Identity = 124/453 (27.37%), Postives = 191/453 (42.16%), Query Frame = 3
Query:  279 KYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILF-YCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSL-PFG-KMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAF---YTGVQ-------VFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLF----WGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWK 1586
            ++    LDHF  +     ++ +Y ++  NW K +  +F + G EG++  +   +G   EL  +   +V   EHRFYG S+ P G KM     ++  YL+S+QALAD A    YL  T     N+  I FGGSY G L+AWFR K+P++V  ++A+SAPV    + +  N           V G++ C+  V  A++ +        L+ L + F +C P    D L  L    L D+ M+   Y       MP   +   C  +     +  Q L A    Y  ++        + N+   +    A  +  G+    W  QTCTE           D  +      + N   C   +GV P        F    +G      S I+F NG +DPW A  V  +   S   I I   AH  ++  + PSD   +  AR      +  W+ + K
Sbjct:   73 RFLQQPLDHFDRRTKET-YKQRYWVNNMNWKKPDGPVFLFIGGEGALSEYDVLAGEHVELSAKYGALVAAVEHRFYGESINPDGLKM-----ENLQYLSSQQALADLASFHAYLVDTYNLTRNNTWICFGGSYPGSLSAWFRLKFPHLVFAAVASSAPVRAQLDFQGYNKVVAASLADKVVGGSDKCLSRVREAFATVDAKLTGKELSGLERDFKSCVPFAGPDDL-ALFASNLADIFMSVVQYNRE----MPNSDIRALCAAMIDTGKSAYQQLVALNENYLSIEQRNCSDNTYANFIADLSNTTATRVGVGM--RQWTYQTCTEFGYYQTCVSERDCPFLQLMTLSWNLDLCDRVFGVDPASVASAVRFTNEYYGADHPRGSRILFVNGDIDPWHALSVLRNETRSEVAIFINGTAHCANMSPTSPSDPPSLTNARLKIDEQVGDWLHQAK 512          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003379.1 (pep scaffold:Pmarinus_7.0:GL476462:377682:381797:1 gene:ENSPMAG00000003081.1 transcript:ENSPMAT00000003379.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.9214 bits (141), Expect = 2.744e-10
Identity = 52/185 (28.11%), Postives = 91/185 (49.19%), Query Frame = 3
Query:  333 FQMKYLISTENWVKGNAILF-YCGNEGSIELFANNSGFVWE---LGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPV-IAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKM 872
            F+ +  +++  W +    +F Y G E ++    +N  FV +   L +    +++ AEHRFYG S+    +S    ++  YL   QALAD   +  Y  +   G +     ++FGGSY G L+AWFR K+P ++  ++A+SAPV    +    +       R   V G++ CV ++   +    K+
Sbjct:   16 FKQRVWVNSLFWKRPRGPVFLYIGGESALN---SNDVFVGQHVRLAQSHGALLVAAEHRFYGKSVNEEGLS---DKNLRYLTISQALADLVRVHHYYVSDEFGLKQGHAWVSFGGSYPGSLSAWFRLKHPELIHTAVASSAPVRAQLDYAGYDEVVGQSLRNSMVGGSDECVSSMREGFENGDKL 194          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Match: EDO36007 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJW1])

HSP 1 Score: 385.185 bits (988), Expect = 7.938e-129
Identity = 193/434 (44.47%), Postives = 278/434 (64.06%), Query Frame = 3
Query:  297 LDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMD-DPVGLTNLSKIFHTCKPLKSADSLIGL---LTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP-ANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
            LDHF ++  SA F  +YL++  NW KG  I FY GNEG I  FANN+GF+W+  ++   M++FAEHR+YG +LPFGK SY   ++ GYL+SEQALAD+A L+ ++K T  GA  SPVIA GGSYGGML++W R KYPN+V  ++AASAP+L    +  C     ++T+ F   G ++CV+++  +WSVI+K+     G   L+ +F+TC P+K+  ++  L   L++   ++ M NYPY   FL P+PAWP+   C  L+      + LL A    V V++N +GQ +C   +      L D GW+ Q CTE+ MPMC+DG+ DMF   ++D     ++C  SYGV PR  W +  + G+ + A SNI+FSNG LDPW AGGV  S +PS+  +L++ GAHH+DLR S+P+D   +  AR+ EK  + +WISE+
Sbjct:    1 LDHFNFRT-SATFSQRYLVNIANWRKGGPIFFYTGNEGDITWFANNTGFMWDNAKEFGAMLVFAEHRYYGETLPFGKRSYESPKYLGYLSSEQALADFATLIRHIKLTTPGATGSPVIAIGGSYGGMLSSWIRMKYPNLVTAALAASAPILYFQGLTPCEGFNEIVTKDFHRDGGDSCVNSIRKSWSVIEKLGATQSGRKTLTSVFNTCSPIKTKYNVTQLQDWLSETWANLAMVNYPYAATFLEPLPAWPIKKVCSHLTDADLPDVALLKAVAGAVGVYYNSSGQAKCFNLSQQAVSSLGDKGWDFQACTEMVMPMCSDGVNDMFKPVKWDFEAFAESCQGSYGVKPRQYWVEVQYGGRDISAHSNIIFSNGLLDPWFAGGVTKSLSPSLVAVLVEEGAHHLDLRHSNPADPPSLIKARQTEKEYLHRWISEY 433          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Match: EDO48107 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK54])

HSP 1 Score: 312.383 bits (799), Expect = 1.905e-100
Identity = 188/451 (41.69%), Postives = 262/451 (58.09%), Query Frame = 3
Query:  267 KYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIK--KMDDPVGLTNLSKIFHTCKPLKSADS---LIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAF---YTG----VQVFFNYTGQIRCLPANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWIS 1577
            ++ T  F   +DHF +   S  F+ +YL + + W     I FY GNEG I  F  NSGFV+E  +  S +VIF EHR+YG SLPFG+ S+   ++ GYL+ EQALAD+A L+  LK     AE  PV++FGGSYGGML+A+ R KYPN++  ++AASAP+  + ++   ++ F  +TR FK   +  C D V   +  +   K +   GL  +SK F  CKPLKSAD    LIG + +    + M +YPY T+FL P+PA PV   CK L+T  +    L +A    Y G    ++ F  +T  + C  A+P   GL +    W+ Q CTELPMP  T+ +TDMF    +  ++    C   + V PR  W     WG+ +  ASNI+FSNG LDPW  GGV  S +PS+  +L++ GAHH+DLRSS+P D   +  AR++E   I KWIS
Sbjct:    2 QFKTGTFEQTVDHFNFIQ-SGTFKQRYLYTEKYWDGKGPIFFYSGNEGGITGFWENSGFVFEAAKNFSALVIFGEHRYYGESLPFGQDSFK-IENIGYLSIEQALADFATLIPALKKQFK-AEEKPVVSFGGSYGGMLSAYLRFKYPNVIQAALAASAPIYFIADLSIRDFFFPAVTRDFK-NADPKCPDLVRAGFIELDNLKKEGLKGLDAISKAFKLCKPLKSADQINHLIGWIRNAFTIIAMCDYPYATDFLAPLPANPVNYACKLLATASDRLSGLADAAGLAYNGTSGTLKCFDPWTEFVEC--ADPTGCGLGNANLAWDYQACTELPMPAGTNNVTDMFPVLPWTLDMRADYCQKHWQVKPRLEWPGISLWGRDISTASNIIFSNGNLDPWRPGGVLKSVSPSLVAVLVEGGAHHLDLRSSNPEDPPSVVAAREMELELIRKWIS 446          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Match: EDO29742 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2S3])

HSP 1 Score: 194.897 bits (494), Expect = 1.234e-57
Identity = 120/282 (42.55%), Postives = 167/282 (59.22%), Query Frame = 3
Query:  270 YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIK--KMDDPVGLTNLSKIFHTCKPLKSADS---LIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNA 1100
            + T  F   +DHF +   S  F+ +YL + + W     I FY GNEG I  F  NSGFV+E  +  S +VIF EHR+YG SLPFG+ S+   ++ GYL+ EQALAD+A L+  LK     AE  PV++FGGSYGGML+A+ R KYPN++  ++AASAP+  + ++   ++ F  +TR FK   +  C D V   +  +   K +   GL  +SK F  CKPLKSAD    LIG + +    + M +YPY T+FL P+PA PV   CK L+T  +    L +A
Sbjct:    1 FKTGTFEQTVDHFNFIQ-SGTFKQRYLYTEKYWDGKGPIFFYSGNEGGITGFWENSGFVFEAAKNFSALVIFGEHRYYGESLPFGQDSFK-IENIGYLSIEQALADFATLIPALKKQFK-AEEKPVVSFGGSYGGMLSAYLRFKYPNVIQAALAASAPIYFIADLSIRDFFFPAVTRDFK-NADPKCPDLVRAGFIELDNLKKEGLKGLDAISKAFKLCKPLKSADQINHLIGWIRNAFTIIAMCDYPYATDFLAPLPANPVNYACKLLATASDRLSGLADA 278          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Match: EDO31220 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYK4])

HSP 1 Score: 129.028 bits (323), Expect = 7.860e-32
Identity = 112/452 (24.78%), Postives = 201/452 (44.47%), Query Frame = 3
Query:  285 FSTYLDHFTYKNDSAKFQMKYLISTENWVKG--NAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPL-KSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFY------TGVQVFFNYTGQIRCLPANPITP-GLD-DNGWNVQTCTELPMPMCTDGITDMFYENRF----DKNVNDKNCHLSYG-VSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            F  Y+DHF +      +  +Y ++   W KG    +L Y G E  +       G + ++ ++   ++   EHR+YG S  FG +    +++  YL+S+ ALAD A  + + K      + +  I +GGSY G L+AWFR KYP++V G++A+SAPV    + ++ N        +  V G++ C+ N+  A+  + ++ D      L K F  C  + K  D+ +       F MG+  Y         +P   +   CK ++    +P + L+  Y      T     F+Y   ++ +      P G D    W  Q+CT+       +  T   +  R     D ++  +   ++ G +  R  +    + GKR    S IVF NG +DPW +  V  +   S   + I   +H  ++ ++ P+D   +  AR+     + +W+ E + +
Sbjct:   61 FEQYIDHFEFTPRPRTYLQRYWMNRAFW-KGPDGPVLLYVGGESVLSGGYIAGGHIVDIAKEYGALLFAVEHRYYGKSNFFGCLK---TKNMRYLSSQLALADLAQFVAHAKNKFGLTDKNKWITYGGSYPGSLSAWFRIKYPHLVIGAVASSAPVEAQTDFKDYNNVVASSLSSPLVGGSKLCMHNIEEAFKFVDRLLDTKNFKTLEKDFIACNDISKLNDTWMFASNLAGFFMGLVQYN------NQVPGINIAYVCKQMNNASRSPYKSLSILYKQQIQKTASCSDFSYENFMKTVKTQKRDPDGFDMIRQWYYQSCTQFGYFQTCEPGTHCVFSKRLGIINDMDLCQEVFEIALGQLKARINFTNEYYGGKR-PRGSKIVFVNGSIDPWHSLSVVTNQTSSEVAVFIPGTSHCANMGANQPNDPPALVEARRRVTAIVGEWLKEAQAA 501          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Match: EDO43517 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYG7])

HSP 1 Score: 112.079 bits (279), Expect = 1.897e-26
Identity = 125/451 (27.72%), Postives = 187/451 (41.46%), Query Frame = 3
Query:  282 YFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKK-MDDPVGLTNLSKIFHTCKPL-KSADSLIGLLTD---GLFDMGMANYPYPTNFLGPMPAWPVTV--FCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPA---NPI----------TPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            +F   LDHF   N     Q  Y   T    K + +    G EG+I       G + +  E    M    EHRFYG S P   MS     +  YLNSEQALAD A     +        +S  I+FGGSY G L+AW R KYP+++ G++A+SAPVL   N         V+T + +  G + C  N+ NA + I++ +D   G   L+ +F  C+PL +  D+ +   +    GLF MG+  Y         +P   +T+   C  ++     P  +    Y  +      T   +CL A   N I          +       W  QTCTE      TD     F + RF    + + C   +G +         F    L  AS I  +N     +   G+ +S +    +      AH  ++     SD+  ++ AR++ K  I KW+
Sbjct:   18 WFIQRLDHFDDSNTETWKQRFYYNDTFRKTKDSPVFLMVGGEGAISPVWVLIGNMMKYAEGFGAMAFILEHRFYGQSHPRSDMS---DANLKYLNSEQALADLAAFRQAMSVKF-NLTDSKWISFGGSYPGSLSAWLRLKYPHLIHGAVASSAPVLAQLNFPEY---LEVVTASLETTGPD-CTKNIANATAAIEELLDADEGTKKLTNLFRVCEPLNRRNDNDVSTFSSNLAGLF-MGVVQYNKDNRAFEGVPGTNITIATVCGIMNDKSLGPALMR---YAKLNSLILDTYGEKCLDASYQNAINSLRNVSWDSSAAEGGRQWTYQTCTEFGFYQTTDSDNQPFGK-RFPLKYSIQQCMDVFGEA---------FNSSNL--ASGIRQTN---TNYGGKGIASSRDIVFVVFYPTGTAHCANMYPESDSDSPQLKQAREVIKQHIAKWL 441          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Medaka
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:101171930])

HSP 1 Score: 350.132 bits (897), Expect = 7.653e-114
Identity = 193/446 (43.27%), Postives = 271/446 (60.76%), Query Frame = 3
Query:  270 YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPV-GLTNLSKIFHTCKPLKS-ADSLI--GLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLS-TPINNPIQLLNAFYTGVQVFFNYTGQIRCL-PANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWK 1586
            Y T YF+  ++HF +  D   F+ +YL++ ++W + +  ILFY GNEG I  F NN+GF+WE+ E+L  M++FAEHR+YG SLPFG+ SY+ S+H  YL SEQALAD+A L+  LK+ +     SPVI+ GGSYGGML+AW R KYPN+V G++AASAP+     +  C   ++++T+ F  K  + C   +  +W  I  +     GL  LS+ F  C PLK+  D++I  G L +   ++ M +YPY  +FL P+PAWP+ V CK L+     +   LL+      +V++NYTG   CL  +   T  L   GW  Q CTE+ MPMCTDG+ DMF    ++       C+  +GV PR  W  TL+ GK + + SNI+FSNG LDPWSAGGV  +   S+  I+I +GAHH+DLR S   D   +R AR LE     +WI + K
Sbjct:   52 YKTFYFNQRINHFGFLED-GTFKQRYLVADKHWQEPDGPILFYTGNEGDITWFCNNTGFMWEIAEELGAMLVFAEHRYYGESLPFGQDSYSDSKHLNYLTSEQALADFAVLIQNLKSKMP---ESPVISVGGSYGGMLSAWLRMKYPNVVVGALAASAPIWQFPRMVGCGDFYKIVTQDF-AKSGQNCDVTIRRSWKAINNLSSTASGLQWLSEEFSLCSPLKTKTDAVIFKGWLQETWVNLAMVDYPYEASFLQPLPAWPIQVVCKYLAFDSKASDYDLLHGVSQAAKVYYNYTGSSSCLNTSQTATSSLGALGWTYQACTEMVMPMCTDGVQDMFEPEDWNFQAFSDECYSMFGVRPREDWAGTLYGGKDISSHSNIIFSNGGLDPWSAGGVTYNITESLVSIMIPDGAHHLDLRYSTDLDPPSVRAARALELKFFQEWIDKTK 492          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Medaka
Match: dpp7 (dipeptidyl peptidase 7 [Source:NCBI gene;Acc:101156583])

HSP 1 Score: 301.597 bits (771), Expect = 2.383e-95
Identity = 189/451 (41.91%), Postives = 258/451 (57.21%), Query Frame = 3
Query:  267 KYDTKYFSTYLDHFTYKN-DSAKFQMKYLISTENWVKGNA-ILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSAD---SLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLP--------ANPITPGLDDN--GWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            ++  KYFS  +DHF + +  +  F  +YLI+   W + +  + FY GNEG I  FA NSGF+ EL  Q   +VIFAEHR+YG SLPFG  S++  +  G L  EQALADYA ++T LK  + GA  SPVIAFGGSYGGML+ + R KYPNIVAG++AASAP+L    + +    FR +T  F+ + + AC   V  A+  +++  +    +++      C+P  SA     L GLL +    M M +YPY T+F+G +PA PV V C    T +  P  L N   T   V+ N +G + C          A+P   GL  N   W+ Q CTE+ M   ++ +TDMF    F ++     C   +GV PR GW +  FWG  L AASNI+FSNG LDPW+ GGV  S +PS+  I I  GAHH+DLR S+ +D   +  ARK+E   I  W+
Sbjct:   34 QFTEKYFSQVVDHFNFNSLGNRTFNQRYLITDRFWRRSSGPVFFYTGNEGDIWEFALNSGFIMELAAQQEALVIFAEHRYYGRSLPFGNNSFSIPE-VGLLTVEQALADYALMITELKLQL-GAAQSPVIAFGGSYGGMLSVYMRLKYPNIVAGALAASAPILSTAGLGDPRQFFRDVTADFE-RVSPACRGAVTAAFQQLREAAERRDYSHIQAELSLCQPPSSAQDVHQLYGLLRNAFTLMAMLDYPYSTHFMGSLPANPVKVACD---TMLGGPDLLTNLRDTAGMVY-NSSGLLPCFDLYSLYVECADPTGCGLGFNSLAWDYQACTEIEMCYESNNVTDMFPAMTFTEDARQLYCSKRWGVQPRPGWLRLQFWGDDLSAASNIIFSNGDLDPWANGGVRTSLSPSLIAINISGGAHHLDLRGSNAADPESVIKARKMEAELIAAWV 477          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Medaka
Match: prss16 (putative serine protease K12H4.7 [Source:NCBI gene;Acc:101158124])

HSP 1 Score: 120.553 bits (301), Expect = 1.068e-28
Identity = 134/459 (29.19%), Postives = 192/459 (41.83%), Query Frame = 3
Query:  273 DTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNV-ENCNYAFRVLTRAFKVKGNEACVDNVHNAW-SVIKKMDDPVGLTNLSKIFHTCKPLK---SADS--LIGLLTDGLFDMGMANYPYPTNFLGPMPA-WPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPA----------NPITPGLDDNG---WNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPR---WGWGQT-LFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            + ++F+  LDHF    DS  ++ +Y ++   +  G  +    G EG        +G      E+L  + +  EHR+YG S P   +S N   +  YL+S QALAD A   T +     G  N+  +AFGGSY G LAAWFR KYP++V  S+A SAPV    N  E     +R L        N  C   V  A  S+++K+ DP    N++K F+ C  L+     DS   + +L     D+   N      F G       + V C  +S P    +    A Y  V      T  ++CL A          N    G   NG   W  QTCTE      TD     F    F  +   K C   Y +S         QT  ++G     +S IVF NG +DPW A G+       +  + IK  AH  ++  +   D   +  AR      + +W+
Sbjct:   45 EEQWFTQKLDHFN-GADSRAWKQRYFLNEAFYKPGGPVFLMIGGEGPANPAWMKNGTWLIYAEKLGALCLMLEHRYYGKSHPTLDLSTN---NLRYLSSRQALADLAHFRTVMGEA-QGLTNNKWVAFGGSYPGSLAAWFRLKYPHLVHASVATSAPVHATVNFPEYLEVVWRSLASE-----NAKCPLLVKKASDSLVEKLKDPETFDNITKDFNLCSKLQIQTEMDSAYFLEMLAGNFMDVVQYNED-NREFEGVQGGNITIKVLCDVMSDP---SLGDAYARYAAVARLLMDTFSLKCLDASFSNYLRDMTNTSWEGPSANGGRQWVYQTCTEFGFYQSTDSPNQPF--TGFPLDYQLKQCADFYNISAEQVAQAVAQTNEYYGGYNIKSSRIVFPNGSIDPWHALGITQDITADLPAVFIKGTAHCANMYPARSQDLPQLSLARDHVLLLLQQWL 487          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Medaka
Match: ENSORLT00000010681.2 (thymus-specific serine protease-like [Source:NCBI gene;Acc:101175669])

HSP 1 Score: 78.1814 bits (191), Expect = 7.693e-15
Identity = 87/326 (26.69%), Postives = 155/326 (47.55%), Query Frame = 3
Query:  342 KYLISTENWVKGNAILF-YCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSL-PFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVH-------------NAWSVIKK----MDDPVGLTNLSKI---FHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPAN---PITPGLD---------DNGWNVQTCTE 1217
            K+ ++  +W + +  +F + G EG I  F   +G   E+ +Q   +++  EHRFYG S+ P G  +    +    L+S+QALAD A    Y+  +   +  +P I+FGGSY G L+AWFR K+P++V  ++A+SAP+    +  + N+   V  R        AC  +++               W+ +++    ++  +   NLS++   F+ C+  K+ D  I L+ + L D+ M    Y  N  G + +  V   C  ++   N+  +  +  +  VQV+ + T + +CL  +    I   +D         +  W  QTCTE
Sbjct:   14 KFFVNEAHWQRPDGPVFLFIGGEGPIFSFDVLAGHHVEMAQQHGALLLAVEHRFYGDSINPDGLKT----ESLADLSSQQALADLATFHGYICRSFNLSSRNPWISFGGSYSGALSAWFRGKFPSLVYAAVASSAPIKAKLDFSDYNH---VNVRVNASTCLHACDSSLYLSDCRFWLSLLFLQCWAQVQQAFAAVEAELLTGNLSQVAGDFNCCQIPKNLDDQIELMQN-LADLFMGTVQY--NEEGVLLS--VKELCDLMTNMCNS--EPSSRSFVSVQVYRSST-EDKCLDVSHEETIKHLMDTSVHSSRRAERQWTYQTCTE 324          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Match: SMESG000074424.1 (SMESG000074424.1)

HSP 1 Score: 950.658 bits (2456), Expect = 0.000e+0
Identity = 473/476 (99.37%), Postives = 473/476 (99.37%), Query Frame = 3
Query:  165 MGFVTLLLMISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            MGFVTLLLMISGFTIAFSVKDYKIKKF VNI QYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQALADYADLLTYLKATIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNV NAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS
Sbjct:    1 MGFVTLLLMISGFTIAFSVKDYKIKKFDVNIEQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQALADYADLLTYLKATIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVRNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 476          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Match: SMESG000074424.1 (SMESG000074424.1)

HSP 1 Score: 936.791 bits (2420), Expect = 0.000e+0
Identity = 465/468 (99.36%), Postives = 465/468 (99.36%), Query Frame = 3
Query:  189 MISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 1592
            MISGFTIAFSVKDYKIKKF VNI QYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQALADYADLLTYLKATIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNV NAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS
Sbjct:    1 MISGFTIAFSVKDYKIKKFDVNIEQYKYDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQALADYADLLTYLKATIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVRNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNVQTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEWKGS 468          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Match: SMESG000074421.1 (SMESG000074421.1)

HSP 1 Score: 490.73 bits (1262), Expect = 3.228e-169
Identity = 244/458 (53.28%), Postives = 319/458 (69.65%), Query Frame = 3
Query:  225 DYKIKKFIVNIVQYK--YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLST-PINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITP-GLDDNGWNVQTCTELPMPMCTDGITDMFY-ENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
             Y   K I  +  YK  Y+T+YF TY+DHFT+KN+S KF +KYLIST+ W KGN ILFYCGNE +IE FA  SG +WELGEQLS +V+FAEHR+YGSSLPFG  S++ +++FGYL  EQ +ADYA LLTYLK+ I GA  SPVIAFGGSYGGMLAAW R KY NIVAGSI++SAP LMVGN +NCN  F+V+++ ++ +G++ C +N+   W +IK +++  GL +LSKIFH C+PLK  ++LI  L   LF++ +AN+PY  +   P+PAWPV  FCK  +   +++   +L +FY  +Q++ N T   +CL          +   W +QTC ELP PMC +GI D+++ EN   +   +  C   YG+ PR  W   LF G   ++ SNI+FSNG LDPWSAGG+  SSN  +Q+I I NGAHHVDLR SHP DT+DI+ ARKLEK  I KWISEW
Sbjct:   11 SYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNYALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEW 468          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Match: SMESG000074421.1 (SMESG000074421.1)

HSP 1 Score: 491.115 bits (1263), Expect = 3.812e-169
Identity = 244/458 (53.28%), Postives = 319/458 (69.65%), Query Frame = 3
Query:  225 DYKIKKFIVNIVQYK--YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLST-PINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITP-GLDDNGWNVQTCTELPMPMCTDGITDMFY-ENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 1583
             Y   K I  +  YK  Y+T+YF TY+DHFT+KN+S KF +KYLIST+ W KGN ILFYCGNE +IE FA  SG +WELGEQLS +V+FAEHR+YGSSLPFG  S++ +++FGYL  EQ +ADYA LLTYLK+ I GA  SPVIAFGGSYGGMLAAW R KY NIVAGSI++SAP LMVGN +NCN  F+V+++ ++ +G++ C +N+   W +IK +++  GL +LSKIFH C+PLK  ++LI  L   LF++ +AN+PY  +   P+PAWPV  FCK  +   +++   +L +FY  +Q++ N T   +CL          +   W +QTC ELP PMC +GI D+++ EN   +   +  C   YG+ PR  W   LF G   ++ SNI+FSNG LDPWSAGG+  SSN  +Q+I I NGAHHVDLR SHP DT+DI+ ARKLEK  I KWISEW
Sbjct:   20 SYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNYALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEW 477          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Match: SMESG000048843.1 (SMESG000048843.1)

HSP 1 Score: 275.404 bits (703), Expect = 1.520e-85
Identity = 172/448 (38.39%), Postives = 257/448 (57.37%), Query Frame = 3
Query:  297 LDHFTY----KNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQXXXXXXXXXXXXXXTIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDP--VGLTNLSKIFHTCKPLKS-ADSLIGL--LTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRC-------LPANPITP---GLDDNGWNVQTCTELPMPMCTDGIT-DMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSN--PSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWI 1574
            LDHF +    +  + KF+ +YL   + +  G  I FYCGNEGSIE F NN+GF++EL  + + +V+F EHR+YG SLPFG ++     +  YL+ EQALAD+  +++Y+K     A NS VIAFGGSYGG LAA+ R KYPNIV G++AAS+P+  V   +  +  F ++T+ F    N  CV+ V + +  +  +      GL  +S+   TCKPL S AD    +  L +    + M +YPY TNF+G +PA+PV V C+ +    NNPI  L        VF+N +  ++C       +  + IT    G D   W+ Q CTE+ +    +  + DMF +    K   D++C   + +       + L WG  +  A+N++FSNG LDPWS GG+ ++S+  PS   +LI+ GAHH+DLRSS+P+D   +R  R++E+  I  W+
Sbjct:   35 LDHFNFLSVSRGYAIKFKQRYLYEDKWYKPGGPIFFYCGNEGSIEGFWNNTGFMFELAPKFNALVVFGEHRYYGVSLPFGSINSFQQPYIQYLSVEQALADFVYMISYVKDKF-NANNSDVIAFGGSYGGCLAAYMRFKYPNIVLGALAASSPIGWVSGSKGFHKFFEIITKDF-YDINPKCVEIVQDGFEEMITLAGKGLTGLDTISRYLKTCKPLTSMADVTYAMKWLRNAFVMLAMMDYPYKTNFMGSLPAFPVNVSCQNILANKNNPIIALR---EAAAVFYNQSKPLKCFSPMDLYIECSDITGCGLGPDSLAWDFQACTEMKLYDDNNATSADMFPDLPLTKKDVDRHCMKKFEIQRAPNQLKFLEWGNDVRTATNVIFSNGNLDPWSLGGIVSNSSLQPSSVALLIQGGAHHLDLRSSNPADPPSVRTVRQIEEKYIRAWL 477          
The following BLAST results are available for this feature:
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PRCP1.094e-11942.44prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGN... [more]
PRCP3.419e-11841.29prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGN... [more]
DPP71.298e-9740.44dipeptidyl peptidase 7 [Source:HGNC Symbol;Acc:HGN... [more]
PRCP2.037e-5944.02prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGN... [more]
PRCP1.110e-4745.60prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pcp-57.789e-9839.48Prolyl carboxy peptidase like protein 5 [Source:U... [more]
pcp-57.789e-9839.48Prolyl carboxy peptidase like protein 5 [Source:U... [more]
pcp-56.902e-9739.48Prolyl carboxy peptidase like protein 5 [Source:U... [more]
pcp-15.628e-5934.21Putative serine protease pcp-1 [Source:UniProtKB/... [more]
pcp-15.628e-5934.21Putative serine protease pcp-1 [Source:UniProtKB/... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG24939.949e-11240.89gene:FBgn0032864 transcript:FBtr0081363[more]
CG24939.949e-11240.89gene:FBgn0032864 transcript:FBtr0332970[more]
CG99536.431e-2626.11gene:FBgn0035726 transcript:FBtr0076898[more]
CG37342.023e-2325.52gene:FBgn0038700 transcript:FBtr0339152[more]
CG37342.023e-2325.52gene:FBgn0038700 transcript:FBtr0083755[more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prcp1.532e-11443.92prolylcarboxypeptidase (angiotensinase C) [Source:... [more]
dpp79.388e-9940.51dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
dpp73.050e-9841.56dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
dpp73.050e-9841.56dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
dpp73.050e-9841.56dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prcp9.544e-13645.03prolylcarboxypeptidase [Source:NCBI gene;Acc:78009... [more]
prcp1.512e-13247.02prolylcarboxypeptidase [Source:NCBI gene;Acc:78009... [more]
prcp2.032e-13247.24prolylcarboxypeptidase [Source:NCBI gene;Acc:78009... [more]
prcp2.391e-13247.24prolylcarboxypeptidase [Source:NCBI gene;Acc:78009... [more]
prcp2.829e-13247.24prolylcarboxypeptidase [Source:NCBI gene;Acc:78009... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Prcp3.903e-12243.92prolylcarboxypeptidase (angiotensinase C) [Source:... [more]
Prcp1.628e-11142.21prolylcarboxypeptidase (angiotensinase C) [Source:... [more]
Dpp76.986e-8639.61dipeptidylpeptidase 7 [Source:MGI Symbol;Acc:MGI:1... [more]
Prss164.513e-2625.93protease, serine 16 (thymus) [Source:MGI Symbol;Ac... [more]
Prss162.261e-926.49protease, serine 16 (thymus) [Source:MGI Symbol;Ac... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7TMR0|PCP_MOUSE2.730e-12143.92Lysosomal Pro-X carboxypeptidase OS=Mus musculus O... [more]
sp|P42785|PCP_HUMAN5.253e-11942.44Lysosomal Pro-X carboxypeptidase OS=Homo sapiens O... [more]
sp|Q5RBU7|PCP_PONAB5.666e-11842.00Lysosomal Pro-X carboxypeptidase OS=Pongo abelii O... [more]
sp|Q2TA14|PCP_BOVIN1.474e-11341.85Lysosomal Pro-X carboxypeptidase OS=Bos taurus OX=... [more]
sp|Q9UHL4|DPP2_HUMAN6.236e-9740.44Dipeptidyl peptidase 2 OS=Homo sapiens OX=9606 GN=... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
Q08D721.497e-13245.03Prolylcarboxypeptidase (Angiotensinase C) OS=Xenop... [more]
A0A5G3HCF41.499e-13245.03Uncharacterized protein OS=Xenopus tropicalis OX=8... [more]
A0A1L8HJS72.280e-13144.19Uncharacterized protein OS=Xenopus laevis OX=8355 ... [more]
A0A1V4JRH32.167e-13046.94Lysosomal Pro-X carboxypeptidase OS=Patagioenas fa... [more]
A0A564Z3X44.138e-13045.49Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
prcp8.881e-11341.83prolylcarboxypeptidase [Source:NCBI gene;Acc:10303... [more]
dpp71.214e-8438.80dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
ENSAMXT00000015346.24.063e-2626.39serine protease 16 [Source:NCBI gene;Acc:103045980... [more]
prss168.709e-2326.88putative serine protease K12H4.7 [Source:NCBI gene... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
dpp72.196e-3933.21dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
ENSPMAT00000005355.11.598e-3127.37pep scaffold:Pmarinus_7.0:GL477796:147175:163357:-... [more]
ENSPMAT00000003379.12.744e-1028.11pep scaffold:Pmarinus_7.0:GL476462:377682:381797:1... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO360077.938e-12944.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO481071.905e-10041.69Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO297421.234e-5742.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO312207.860e-3224.78Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO435171.897e-2627.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
prcp7.653e-11443.27prolylcarboxypeptidase [Source:NCBI gene;Acc:10117... [more]
dpp72.383e-9541.91dipeptidyl peptidase 7 [Source:NCBI gene;Acc:10115... [more]
prss161.068e-2829.19putative serine protease K12H4.7 [Source:NCBI gene... [more]
ENSORLT00000010681.27.693e-1526.69thymus-specific serine protease-like [Source:NCBI ... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000074424.10.000e+099.37SMESG000074424.1[more]
SMESG000074424.10.000e+099.36SMESG000074424.1[more]
SMESG000074421.13.228e-16953.28SMESG000074421.1[more]
SMESG000074421.13.812e-16953.28SMESG000074421.1[more]
SMESG000048843.11.520e-8538.39SMESG000048843.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004948 ID=SMED30004948|Name=Lysosomal Pro-X carboxypeptidase|organism=Schmidtea mediterranea sexual|type=transcript|length=1837bp
ATCCAGGTAAGTGTTTTCAATATCTTATAGAATTTTTATTTAATTAGTAC
AAGATTATTATTCCGATAAATTTTAATCAAAAAATCATTTAATATTTTCA
TAAAATTTACGAATTTATTTTAAATATTTTTTGAAAAATTTAAAATTTCC
AAATGATTTCTCAGATGGGTTTTGTAACTCTTTTGCTCATGATTTCAGGA
TTTACAATCGCATTTTCTGTAAAAGACTATAAAATTAAGAAATTTATTGT
CAATATAGTACAATATAAATATGATACAAAGTATTTCTCCACTTACCTGG
ATCATTTCACATATAAAAATGACAGTGCGAAATTTCAAATGAAGTATTTG
ATTTCCACTGAAAATTGGGTGAAAGGGAATGCCATCTTATTTTACTGTGG
AAATGAAGGTTCCATTGAACTGTTTGCCAACAACTCGGGATTCGTTTGGG
AATTGGGAGAACAATTGTCTACAATGGTGATATTTGCTGAGCATCGATTT
TATGGATCATCTTTGCCGTTCGGTAAAATGTCATACAATGGATCTCAGCA
TTTTGGGTACTTGAATTCTGAACAAGCTCTCGCTGATTACGCTGATTTAT
TGACATATTTGAAAGCTACTATTGCCGGGGCTGAAAATTCTCCAGTAATT
GCTTTTGGAGGTTCGTATGGAGGAATGCTAGCAGCTTGGTTCAGACAGAA
ATATCCAAATATTGTTGCAGGGTCAATAGCAGCTTCGGCTCCAGTTTTAA
TGGTTGGAAACGTTGAAAATTGTAATTATGCATTTCGTGTTCTTACTCGA
GCTTTTAAAGTCAAAGGAAATGAGGCCTGTGTTGATAATGTTCATAATGC
CTGGTCTGTTATAAAGAAAATGGATGATCCTGTCGGTCTTACAAATTTGT
CGAAAATATTTCATACCTGTAAACCGTTAAAATCGGCGGATAGTTTGATA
GGTTTATTAACTGATGGCTTGTTTGATATGGGTATGGCTAATTATCCATA
TCCAACAAATTTTCTCGGTCCAATGCCAGCTTGGCCTGTTACGGTCTTTT
GCAAACCTTTGTCTACTCCTATAAATAATCCTATTCAACTGTTAAACGCT
TTCTATACTGGTGTTCAAGTTTTCTTCAACTACACTGGTCAGATTCGCTG
TTTGCCCGCAAATCCTATTACCCCAGGACTTGATGACAATGGTTGGAATG
TTCAGACTTGTACTGAATTACCAATGCCAATGTGTACAGATGGTATTACT
GATATGTTTTATGAAAATCGTTTCGATAAGAACGTAAATGATAAAAATTG
TCACCTATCATACGGTGTTTCACCCCGATGGGGATGGGGTCAGACATTGT
TTTGGGGTAAACGCCTAGAAGCCGCTTCAAATATTGTATTCAGTAATGGT
TATCTTGATCCTTGGTCAGCTGGCGGAGTTTATAATTCCTCTAATCCATC
TGTCCAAATAATACTGATTAAAAATGGAGCTCATCATGTTGATTTGAGAA
GCTCTCATCCAAGTGACACATCGGACATCCGATTTGCAAGGAAATTGGAA
AAGAATGCAATAATGAAATGGATCAGTGAGTGGAAAGGAAGCTAAATTCA
TCCAAATACCTTTGCTGATTGTCTGTTACAAATTTTATTAAAGATTTATT
TAAATATTAATTAATTTTTTATTTGTGATTTAACCCTCGTGATTTAACTT
GTGAATTAATTATAAAAAGTTGCACAACATATAAAAAAATTAAAAATTAG
ATGCTAAACATTTCTTGCAAATCTTAATCTTCATTCTGTACCATTCACAA
GATTATTTATTGTACTGAGGACAAGTTATTTGGCTTC
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protein sequence of SMED30004948-orf-1

>SMED30004948-orf-1 ID=SMED30004948-orf-1|Name=SMED30004948-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=481bp
MISQMGFVTLLLMISGFTIAFSVKDYKIKKFIVNIVQYKYDTKYFSTYLD
HFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWE
LGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQALADYADLL
TYLKATIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLM
VGNVENCNYAFRVLTRAFKVKGNEACVDNVHNAWSVIKKMDDPVGLTNLS
KIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFC
KPLSTPINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITPGLDDNGWNV
QTCTELPMPMCTDGITDMFYENRFDKNVNDKNCHLSYGVSPRWGWGQTLF
WGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRS
SHPSDTSDIRFARKLEKNAIMKWISEWKGS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR029058AB_hydrolase
IPR008758Peptidase_S28
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
GO:0002155regulation of thyroid hormone mediated signaling pathway
GO:0002353plasma kallikrein-kinin cascade
GO:0003085negative regulation of systemic arterial blood pressure
GO:0042593glucose homeostasis
GO:0043535regulation of blood vessel endothelial cell migration
GO:0060055angiogenesis involved in wound healing
GO:0097009energy homeostasis
GO:2000377regulation of reactive oxygen species metabolic process
Vocabulary: molecular function
TermDefinition
GO:0008236serine-type peptidase activity
GO:0004180carboxypeptidase activity
GO:0008233peptidase activity
GO:0016787hydrolase activity
Vocabulary: cellular component
TermDefinition
GO:0005764lysosome
GO:0045178basal part of cell
GO:0070062extracellular exosome