slc22a-9

Query:  432 STLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYV-ENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKML------KCGKEEE 1643
            ST+VS+F LVC N ++ D+   +    FL G F +G+ +DR+GR  I +LS +    + +++A +PNF  ++ FR L G+     +++  V + E V  + R  +G     ++T+  ++ P  ++   +W+  QL   +PS +F L+ + +PESPRWL    + D+ ++ LR ++K N         +I V +  V   +     +    +  +++ +F  F+  ++Y  +++ +GI+  N+Y+  F+ G++ELP  LL    +  + R++ F     V  +   ++ F  + I   + +R  +  L ++ I+   + + +  +EL+PTT R+FG++  L S    F G +   L+ RL+ +   LP +I+     I G +V   LPETK + +PET+ D++ L      KCG+ ++
Sbjct:  138 STIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFLPEGI---AWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVS--LCSGLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVML-LPETKGIALPETVDDVEKLGSPHSCKCGRNKK 548          

Query:  180 LDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSKSKFIV-----------------------SKDQC---SILMNGTTMNCKE------WDFSLLPIG------------STLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVY-ISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFF-MPESPRWLCVMNRKDEMMESLRFMSKIN---------RLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMK-MLKCGKEEEFVFYMQ 1661
            +D++L    +   F+   FF+L+L +         I+F  F P+ +CR    ++  +                       S  QC    +  N +T +C +       + S LP+G            S++V++F LVC N ++ D+        F +G   +G+++DRFGRK  ++ ++++   + +L+A+SP +   L FR++ GL + A + I  + + E V   +R  +G FY   +TV  +V    ++    WR  Q    +P+ F+L  ++ +PESPRWL   N+  E M  ++ ++K N         RLR + E  +    + +         +    +  +++ ++  F+ +++Y  +++ +G+   N+YL  F   L+E P+  +    +  I R+  +     V       S+F    +     ++I++ CL ++ I+   + + +   EL+PT  R+ G+   + S+     G +   L+ RL+ I   LP L+ F  L +V   +   LPETK   +PET+ + + M +  K +E + Y+Q
Sbjct:    5 VDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHRCRSPGVAELSLRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLGPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPASLQRLRLEEETGKKLNPSFLD------LVRTPQIRKHTMILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLASVFIPGDL---QWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVH--ICSSMCDIGGIITPFLVYRLTNIWLELP-LMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRKNKEKMIYLQ 546          

Query:  429 GSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLI-ESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEG---NICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKR----KIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKML-KCGKEEEFVFYMQNKHKYFNNT 1688
            GS++V++F LVC + +  D+      A FL G   VG+ +DRFGRK  ++ ++++   S +L+A SPN+ + L FR+L GL +   +++   LI E V    R  +   Y   +TV  +     ++    WR  QL   +P+ +F L+ + +PESPRWL    R  E ++ +  +++ N      +   + +E  V E    +     +    + R+ + ++  F+ +++Y  +++ +G  S N+YL      L+E+P   ++   +  + R     +  LL G    +++FIS       P    + I++ C+ ++ I+   Q I +   EL+PT  R+ G+  ++ S+     G +   ++ RL  +   LP LI F+ L ++   V   LPETK + +PET+ D + L +  K +E   Y++ +    + T
Sbjct:  131 GSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFIS-------PDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGV--MVCSSLCDIGGIITPFIVFRLREVWQALP-LILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKENTIYLKVQTSEPSGT 554          

Query:  405 WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYIS-----IVWLIESVSIEFRPF-IGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFI-FFMPESPRWLCVMNRKDEMMESLRFMSKINRLR-----FDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGF---LLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLIN---RLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEE 1643
            W+FS     ST+V+++ LVC++ +   + + +++   LLG F+ G +SDRFGRKN++ +++ ++T  S L   S NF  ++   +L+G+   + Y++        L +SV I F    +  FY F     YMV P+ ++  RDWR+  +   +P V  + + +F+PESPRWL    R +E    +R  +K N +      FD  + Q       +  NI    +  + +  +IM++    +I++ Y  + +D   L  +++++ FL  ++E+P+ +L++ +L+Y+ R+      L +G  GS+LLF+ +       L +V+ +V     K  +++    + VY  EL+PT  R+ G+    +S+  S  G++L      L     FLP ++  S   +  ++  F LPE+   P+P+T+  M  +K  K  +
Sbjct:  117 WEFSQDVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAF----GYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLG--GSVLLFMQLVPPDLYYLATVLVMV----GKFGVTAAFSMVYVYTAELYPTVVRNMGVG---VSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLF-LPESFGTPLPDTIDQMLRVKGMKHRK 534          

Query:  378 NGTTMNCKE---WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWL-IESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIP-SVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYV--ENLVKEGNICVACKDTDFQSRSIMALFCA-------------FSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPL-QSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSF--LWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSS 1715
             G T  C +   +D S  P  ST+V+++ LVC +R L  +   ++    LLG  V G+++DR GR+ ++IL+ +    S    A +PNF  Y  FR+L G++ + + ++ + L +E + I  R  +G+   + +++   +    ++    WR  QL    P   F+++ +F  ES RW     R D  + +L+ +++IN  R +  K  + V   +L KE  +         Q+ ++  L C              F+ +  Y  +++D+     ++YL   + G ++LP+ L+ + V+  + R+   +       LL  I I  +  IP  QS++R  L  L K  +++    I +Y  EL+PT  R  G+ +    + ++  G+++   +S+ +   P++  F +  + +    V   LPET   P+P+T+ D++  K GK+       Q   KY      ++ EK+ 
Sbjct:   99 TGATEPCTDGWIYDNSTFP--STIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTM------GKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQM----AALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGM---GSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRK-GKQTR---QQQEHQKYMVPLQASAQEKNG 549          

Query:  381 GTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVG-FMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYL-FIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRF--------DVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSS--------NMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHR--SFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLID-MKMLK-----CG 1631
            G    CKEW++    +  T+V+++  VCDN +    + M +   +L+G FVG F+SDR+GRK  +    +L      LL  S  F  +L  R LL  +  A  ++  V  +E    ++R  +GS     W   Y    + ++L + W +  L  ++  +  L  ++F+PESPRWL + N+  +  + +R     N+ R           EK +    N  ++ +     + ++ + R+++      +  L+Y  M++ +   SS        N +L+  + G +ELP+L+   ++LR  +++   L++ G G  LL   +   +    QS + ++   LSK  I      + ++ +EL PT  R  + GI+ ++       SG + I  LS ++  L  +  F+   ++   +   LPET+ LP+P+T++D ++M+K     CG
Sbjct:  274 GKINRCKEWEYDTSVMDRTIVTEWNRVCDNNWSRAHVHMSYSLGYLVGCFVGGFISDRYGRKTAITGFGILTMLFGFLLTYSKEFEIFLVVRFLLAATNEAADLAAYVLCMEVTGTKYRSIVGSLIQAPWACGYAFLALIAYLTKSWTMIHLICVLLHIISLMLLYFLPESPRWLILNNKTKQAEKIIREACHYNKSRLPSDLGLVRHAEKKKWMKHN--EKPSYFHLFRSSELRFRNVVLFIVWIATALVYYGMVIALSDQSSPGRRVFDGNFFLNNAMAGAIELPTLVFCVFLLRMGRKRSQMLVLFGSGLFLLTSVVMVYRK---QSTLALIFMLLSKACIQGSFNILYIFTSELNPTVVRNSAVGISSMVARMGAGASGYIAI--LSDVTMPLVPMTIFACFSLLAGCLVLLLPETQGLPLPDTILDSVQMVKRNTKPCG 710          

Query:  435 TLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVG-FMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYL-FIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRF--------DVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSS--------NMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHR--SFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLI 1607
            T+V+++  VCDN +    + M +   +L+G FVG F+SDR+GRK  +    +L      LL  S  F  +L  R LL  +  A  ++  V  +E    ++R  +GS     W   Y    + ++L + W +  L  ++  +  L  ++F+PESPRWL + N+  +  + +R     N+ R           EK +    N  ++ +     + ++ + R+++      +  L+Y  M++ +   SS        N +L+  + G +ELP+L+   ++LR  +++   L++ G G  LL   +   +    QS + ++   LSK  I      + ++ +EL PT  R  + GI+ ++       SG + I  LS ++  L  +  F+   ++   +   LPET+ LP+P+T++
Sbjct:    4 TIVTEWNRVCDNNWSRAHVHMSYSLGYLVGCFVGGFISDRYGRKTAITGFGILTMLFGFLLTYSKEFEIFLVVRFLLAATNEAADLAAYVLCMEVTGTKYRSIVGSLIQAPWACGYAFLALIAYLTKSWTMIHLICVLLHIISLMLLYFLPESPRWLILNNKTKQAEKIIREACHYNKSRLPSDLGLVRHAEKKKWMKHN--EKPSYFHLFRSSELRFRNVVLFIVWIATALVYYGMVIALSDQSSPGRRVFDGNFFLNNAMAGAIELPTLVFCVFLLRMGRKRSQMLVLFGSGLFLLTSVVMVYRK---QSTLALIFMLLSKACIQGSFNILYIFTSELNPTVVRNSAVGISSMVARMGAGASGYIAI--LSDVTMPLVPMTIFACFSLLAGCLVLLLPETQGLPLPDTIL 408          

Query:  183 DNILSDINKPLTFKIVAFFILSLPT-FQSCSQIQNILFALFIPNFKCRFNSKSKFIVS-KDQCSIL----MNGTTMN---------------------CKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGP-FVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVY-ISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYL-FIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIY-----VENLVKE------GNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRK---IGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVL---INRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHK 1673
            D +L  +    T++IV FFI+ LPT   S     NI F +  P   C      +++    +   IL     N T +N                     C+  WD+       +LV++F LVCD +   ++    +Y    +G    G+++D+FGR+    + L +        + + +  +++  R   GL+  A++ I  +  +E +    R F G     ++  A  +  + +   R WR    F   P  FY+ + FF+PESPRW   + +  +  + L+ ++K+N  + +V+ D++       +N  +E       N+    K  + + ++++  +      +IY+ + +++  L  + Y S  + G +ELP   + + +L+   R+      +++ G+G +    ++F     P        +G   K  + S    I ++  EL+PT  R+ G+ +   S+ ++ SG +L   I  L  I   LP LI        G++ +F LPET   P+P T+ D +      E +   + Q   K
Sbjct:   10 DFVLEQVGNYGTYQIVFFFIICLPTSLPSAFSAFNIPFVVGNPPHTCHIPEGKEYLRPLTNDTQILSCKQYNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNSTYLDSLVTEFNLVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRRRSFFVILTVLIVCGTASSFAKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGRIFSGLMTSLFFGAAMALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMNG-KSNVDVDELVDSMKNHQNAAEEKETKRSHNVTDLFKTPNLRRKTLIVTYIWVMNAIIYNGLTLNVSNLPVDDYWSFIINGAVELPGYFVVWPLLQCAGRRWTLAATMIVCGIGCV---SAMFMPDGYPWLVASASFIG---KFGVGSGFAVIYIFAGELYPTVVRAIGMGM---SSMVAGSGLLLAPHIVNLGKIVKILPLLIMGLMALSAGILTFF-LPETLGAPLPMTIEDAENFGKKPEPDSGMFTQAAKK 543          

Query:  183 DNILSDINKPLTFKIVAFFILSLPT-FQSCSQIQNILFALFIPNFKCRFNSKSKFIVS-KDQCSIL----MNGTTMN---------------------CKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGP-FVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVY-ISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYL-FIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIY-----VENLVKE------GNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRK---IGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVL---INRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHK 1673
            D +L  +    T++IV FFI+ LPT   S     NI F +  P   C      +++    +   IL     N T +N                     C+  WD+       +LV++F LVCD +   ++    +Y    +G    G+++D+FGR+    + L +        + + +  +++  R   GL+  A++ I  +  +E +    R F G     ++  A  +  + +   R WR    F   P  FY+ + FF+PESPRW   + +  +  + L+ ++K+N  + +V+ D++       +N  +E       N+    K  + + ++++  +      +IY+ + +++  L  + Y S  + G +ELP   + + +L+   R+      +++ G+G +    ++F     P        +G   K  + S    I ++  EL+PT  R+ G+ +   S+ ++ SG +L   I  L  I   LP LI        G++ +F LPET   P+P T+ D +      E +   + Q   K
Sbjct:   10 DFVLEQVGNYGTYQIVFFFIICLPTSLPSAFSAFNIPFVVGNPPHTCHIPEGKEYLRPLTNDTQILSCKQYNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNSTYLDSLVTEFNLVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRRRSFFVILTVLIVCGTASSFAKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGRIFSGLMTSLFFGAAMALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMNG-KSNVDVDELVDSMKNHQNAAEEKETKRSHNVTDLFKTPNLRRKTLIVTYIWVMNAIIYNGLTLNVSNLPVDDYWSFIINGAVELPGYFVVWPLLQCAGRRWTLAATMIVCGIGCV---SAMFMPDGYPWLVASASFIG---KFGVGSGFAVIYIFAGELYPTVVRAIGMGM---SSMVAGSGLLLAPHIVNLGKIVKILPLLIMGLMALSAGILTFF-LPETLGAPLPMTIEDAENFGKKPEPDSGMFTQAAKK 543          

Query:  183 DNILSDINKPLTFKIVAFFILSLPT-FQSCSQIQNILFALFIPNFKCRFNSKSKFIVS-KDQCSIL----MNGTTMN---------------------CKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGP-FVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVY-ISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYL-FIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIY-----VENLVKE------GNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRK---IGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVL---INRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHK 1673
            D +L  +    T++IV FFI+ LPT   S     NI F +  P   C      +++    +   IL     N T +N                     C+  WD+       +LV++F LVCD +   ++    +Y    +G    G+++D+FGR+    + L +        + + +  +++  R   GL+  A++ I  +  +E +    R F G     ++  A  +  + +   R WR    F   P  FY+ + FF+PESPRW   + +  +  + L+ ++K+N  + +V+ D++       +N  +E       N+    K  + + ++++  +      +IY+ + +++  L  + Y S  + G +ELP   + + +L+   R+      +++ G+G +    ++F     P        +G   K  + S    I ++  EL+PT  R+ G+ +   S+ ++ SG +L   I  L  I   LP LI        G++ +F LPET   P+P T+ D +      E +   + Q   K
Sbjct:   27 DFVLEQVGNYGTYQIVFFFIICLPTSLPSAFSAFNIPFVVGNPPHTCHIPEGKEYLRPLTNDTQILSCKQYNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNSTYLDSLVTEFNLVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRRRSFFVILTVLIVCGTASSFAKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGRIFSGLMTSLFFGAAMALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMNG-KSNVDVDELVDSMKNHQNAAEEKETKRSHNVTDLFKTPNLRRKTLIVTYIWVMNAIIYNGLTLNVSNLPVDDYWSFIINGAVELPGYFVVWPLLQCAGRRWTLAATMIVCGIGCV---SAMFMPDGYPWLVASASFIG---KFGVGSGFAVIYIFAGELYPTVVRAIGMGM---SSMVAGSGLLLAPHIVNLGKIVKILPLLIMGLMALSAGILTFF-LPETLGAPLPMTIEDAENFGKKPEPDSGMFTQAAKK 560          

Query:  375 MNGTTMNCKEWDFSLLP-IGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVG-----FMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGL-SASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFF-MPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCA-FSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSV----IRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGIT--------LLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIV--GVVVYFSLPET 1577
            M+   + C++W++     +G+T  S + LVC+  +L +V  M     FLLG   G     ++SD+FGRK ++ +S VL+T   + L +  +F  YLT R LLGL S S  Y  ++  IE V  ++R   G +  F   ++YM+    ++L +D++  QL   IP +F  F++F +PESPRWL V  R DE+   +   +K N  +   +             ++    + +  +  SI   FC  F++NL+Y  +++++     N+YL+  L GL+E+P++ ++ Y++  + +K  F       +L+         +I         ++I    + K  IS+ N  + VY  EL+PT  R+ G+          L+++ +LS   ++ +N++    + L TL+     W +  G VV F LPET
Sbjct:  140 MDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEM----FFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQDVTYLFRSSYLRRISI-CFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLF-----CATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLVSLPLNKIE--GHLLMTLLT---AWSIFGGFVVLF-LPET 547          

Query:  375 MNGTTMNCKEWDFSLLP-IGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVG-----FMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGL-SASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFF-MPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCA-FSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSV----IRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGIT--------LLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIV--GVVVYFSLPET 1577
            M+   + C++W++     +G+T  S + LVC+  +L +V  M     FLLG   G     ++SD+FGRK ++ +S VL+T   + L +  +F  YLT R LLGL S S  Y  ++  IE V  ++R   G +  F   ++YM+    ++L +D++  QL   IP +F  F++F +PESPRWL V  R DE+   +   +K N  +   +             ++    + +  +  SI   FC  F++NL+Y  +++++     N+YL+  L GL+E+P++ ++ Y++  + +K  F       +L+         +I         ++I    + K  IS+ N  + VY  EL+PT  R+ G+          L+++ +LS   ++ +N++    + L TL+     W +  G VV F LPET
Sbjct:  140 MDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEM----FFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQDVTYLFRSSYLRRISI-CFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLF-----CATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLVSLPLNKIE--GHLLMTLLT---AWSIFGGFVVLF-LPET 547          

Query:  375 MNGTTMNCKEWDFSLLP-IGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVG-----FMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGL-SASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFF-MPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCA-FSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSV----IRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGIT--------LLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIV--GVVVYFSLPET 1577
            M+   + C++W++     +G+T  S + LVC+  +L +V  M     FLLG   G     ++SD+FGRK ++ +S VL+T   + L +  +F  YLT R LLGL S S  Y  ++  IE V  ++R   G +  F   ++YM+    ++L +D++  QL   IP +F  F++F +PESPRWL V  R DE+   +   +K N  +   +             ++    + +  +  SI   FC  F++NL+Y  +++++     N+YL+  L GL+E+P++ ++ Y++  + +K  F       +L+         +I         ++I    + K  IS+ N  + VY  EL+PT  R+ G+          L+++ +LS   ++ +N++    + L TL+     W +  G VV F LPET
Sbjct:  140 MDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEM----FFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQDVTYLFRSSYLRRISI-CFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLF-----CATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLVSLPLNKIE--GHLLMTLLT---AWSIFGGFVVLF-LPET 547          

Query:  375 MNGTTMNCKEWDFSLLP-IGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVG-----FMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGL-SASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFF-MPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCA-FSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSV----IRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGIT--------LLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIV--GVVVYFSLPET 1577
            M+   + C++W++     +G+T  S + LVC+  +L +V  M     FLLG   G     ++SD+FGRK ++ +S VL+T   + L +  +F  YLT R LLGL S S  Y  ++  IE V  ++R   G +  F   ++YM+    ++L +D++  QL   IP +F  F++F +PESPRWL V  R DE+   +   +K N  +   +             ++    + +  +  SI   FC  F++NL+Y  +++++     N+YL+  L GL+E+P++ ++ Y++  + +K  F       +L+         +I         ++I    + K  IS+ N  + VY  EL+PT  R+ G+          L+++ +LS   ++ +N++    + L TL+     W +  G VV F LPET
Sbjct:  140 MDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEM----FFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQDVTYLFRSSYLRRISI-CFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLF-----CATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLVSLPLNKIE--GHLLMTLLT---AWSIFGGFVVLF-LPET 547          

Query:  375 MNGTTMNCKEWDFSLLP-IGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVG-----FMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGL-SASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFF-MPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCA-FSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSV----IRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPET 1577
            M+   + C++W++     +G+T  S + LVC+  +L +V  M     FLLG   G     ++SD+FGRK ++ +S VL+T   + L +  +F  YLT R LLGL S S  Y  ++  IE V  ++R   G +  F   ++YM+    ++L +D++  QL   IP +F  F++F +PESPRWL V  R DE+   +   +K N  +   +             ++    + +  +  SI   FC  F++NL+Y  +++++     N+YL+  L GL+E+P++ ++ Y++  + +K  F       +L+         +I         ++I    + K  IS+ N  + VY  EL+PT  R+ G+    ++  L+      ++ L+ I   L   +  ++    G VV F LPET
Sbjct:  179 MDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEM----FFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQDVTYLFRSSYLRRISI-CFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLF-----CATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLF-LPET 581          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSK------------------SKFIVSKDQC---SILMNGTTMNCKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYI-SIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLF-IFFMPESPRWLCVMNRKDEMMESLRFMSKIN--RLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIG---FLLIGGVGSLLLFISIFFSKSIPLQSV-IRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSG--AVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSK 1739
            M  D +L+ I     ++ + +  + LP       +   +F    P  +CR ++                   S+     D C   S +      NC+  W +S     ST V+++ LVCD R L  +   ++    L+G  V G M+DR+GR+  +++SL L+T   +  A +PNF  Y+  R ++G++ S V I + V   E    + R   G F  +++   YM+    +FL RDWR  QL    P   ++F I+ +P S RWL V NRK+E ++ LR  + +N   L   V+ ++        +  +    +    + R+++  +  F   L+Y  + + +  L +++YL+ F+ GL+E+P+  L   VL    RKI    FL++GG   LL         ++P  S  +R  L  + K  I++    I VY  ELFPT  R  GI   + S F    G  A LIN L   +  +P LI+ S   +    +  +LPET   P+P+++ D        E+  + Y        + + +N++ +  ++L ++ +
Sbjct:    1 MNFDQLLATIGGFGKYQKLLYVWICLPQIFLGFHMMASVFTGATPPHRCRGSTSGMEDWTFTSNLSHVNLSISRLAGFADACTAASGVNRSARTNCETGWVYSHEVFQSTTVTEWDLVCDKRGLSSLGSSIYMLGLLVGAVVFGAMADRYGRRFAMLVSLALQTVFGVAAAFAPNFPVYVGLRFIIGMTVSGVIINAFVLGTEWTCTQRRMLAGIFTDYFFGFGYMLLAGVAFLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNNRKEEAIDLLRKAASVNGRTLPPTVQVERYESPQGRSKYTVVDLLRTPQMRKRALILFYIWFVNVLVYYGLSLGVSDLGADLYLTQFMFGLVEIPARTL-VLVLLPCSRKIPLSVFLVVGGGACLLTL-------TLPADSAHVRTALAMVGKFGITASFAIIYVYSAELFPTVLRQTGIG--VSSMFARMGGVLAPLINLLGRHTPVVPMLIFGSTPLLA-AALALALPETARQPLPDSIHD-------TEKSTLKYDGQIPVQASQSPNNTEGQELQSLADECR 537          

Query:  393 NCKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYI-SIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLF-IFFMPESPRWLCVMNRKDEMMESLRFMSKIN--RLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIG---FLLIGGVGSLLLFISIFFSKSIPLQSV-IRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSG--AVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSK 1739
            NC+  W +S     ST V+++ LVCD R L  +   ++    L+G  V G M+DR+GR+  +++SL L+T   +  A +PNF  Y+  R ++G++ S V I + V   E    + R   G F  +++   YM+    +FL RDWR  QL    P   ++F I+ +P S RWL V NRK+E ++ LR  + +N   L   V+ ++        +  +    +    + R+++  +  F   L+Y  + + +  L +++YL+ F+ GL+E+P+  L   VL    RKI    FL++GG   LL         ++P  S  +R  L  + K  I++    I VY  ELFPT  R  GI   + S F    G  A LIN L   +  +P LI+ S   +    +  +LPET   P+P+++ D        E+  + Y        + + +N++ +  ++L ++ +
Sbjct:   82 NCETGWVYSHEVFQSTTVTEWDLVCDKRGLSSLGSSIYMLGLLVGAVVFGAMADRYGRRFAMLVSLALQTVFGVAAAFAPNFPVYVGLRFIIGMTVSGVIINAFVLGTEWTCTQRRMLAGIFTDYFFGFGYMLLAGVAFLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNNRKEEAIDLLRKAASVNGRTLPPTVQVERYESPQGRSKYTVVDLLRTPQMRKRALILFYIWFVNVLVYYGLSLGVSDLGADLYLTQFMFGLVEIPARTL-VLVLLPCSRKIPLSVFLVVGGGACLLTL-------TLPADSAHVRTALAMVGKFGITASFAIIYVYSAELFPTVLRQTGIG--VSSMFARMGGVLAPLINLLGRHTPVVPMLIFGSTPLLA-AALALALPETARQPLPDSIHD-------TEKSTLKYDGQIPVQASQSPNNTEGQELQSLADECR 524          

Query:  351 SKDQCSILMNGTTMNCKEWDFSLLPIG-STLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVY-ISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYL-FIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVAC---KDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKE 1637
            ++ Q S++   + ++  E+D+    +G  + V++F LVC + +  D+        FL+G   +G+++D++GR    +++      + IL+A SPN+ + L FR L G      + +  V + E V ++ R  +G  Y  ++++  ++ P+ ++   +WR  Q+   +P + +L + +F+PESPRWL   N+  E +E  + ++K NR     + + +  +N +  G+        K    ++ + +  F  F+  ++Y  +++ +GIL  N+Y+   + G++ELP+  L    +  I R++ F     V      I+ F   S+     ++  + C+ ++ I+   + ++    EL+PT  R+ G++  + S      G V   L+ RL+VI   LP +I+ +  ++ G +V   LPETK +P+PET+ D++     KE
Sbjct:  110 NQSQLSVMPMMSCVDGWEYDY----VGRQSFVTEFDLVCGDAWYVDMFQATLSIGFLVGSIAIGYLADKYGRMKSFLMTNFFIGVTGILVATSPNYISLLVFRALFGFGVKGGWMVGYVLITELVGVDHRRTVGVTYQLFFSMGILLLPLLAYFITNWRWLQVVFTVPYICFLTYYWFIPESPRWLLTQNKIAEAVEITKSIAKENRKTLSKKIETLKDDN-IDSGSTASFMDLFKTAKLRTYTFILSFNWFTSAVVYQGLIMRLGILGGNVYVDFLISGIVELPAAFLILLTIERIGRRLPFATANIVAGAACLITAFIPDSMFW---LKSAVACVGRLGITMAFEMVVFVNTELYPTVIRNLGVS--VCSTLCDVGGIVAPFLLYRLAVIWLELPLIIFGALAFVAGGLVLL-LPETKGVPLPETIDDIEHPNRNKE 537          

Query:  306 PNFKCRFNSKSKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLS-ASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFI-FFMPESPRWLCVMNRKDEMMESLRFMSKIN-------RLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKI---GFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLL-LISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENL 1724
            P F+   NS S   +   +C    NG       W F      STL + + LVCD R LG +   +++   + G    G +S  FGRK ++++S +L     +   LS +   +   R   G +   +V IS V  +E VSIE R  +G      WT  +M FP+ ++  RDWR   +   +P+V  +   +++PES RWL V  + D+    L+  + +N       R++ +     I  +   ++ +     +    +  S++     FS+  +   +  +I     NMYL+ F+ G +E+P+    YY+L    R +   G LL  G+      I+IF  K    ++VIR V+  L K   ++    +++Y +EL+PT  R  G+     I+ F      +++    V SYF  + +   FL +    V + LPET    +PET+ D++ ++  K++  +     K +  +N      EK  +NL
Sbjct:    5 PQFQLLINSSSSSDLPVVECQ---NG-------WHFDNSTFISTLATQWDLVCDKRALGKLTTTIFFLGVMFGAAAFGSLSAMFGRKPMLLVSYILGMGFGLCSVLSSSLVMFAVLRFFSGFTITGSVIISTVLNVEWVSIEHRKLVGVIDSLAWTFGFMGFPVIAYFIRDWRWLTVAISLPNVISIITWWWVPESARWLIVNGKADKAHYYLKKCAAMNHKKEVTARIKPEDLSKIIVTDRGSRKYSYLDLVRTPKMRRLSLLTGITWFSVATVAYGISFNITGFGLNMYLTQFVYGAIEIPAKFCIYYLLDKFGRHVTQAGSLLFVGIS---FIINIFIPKE---KTVIRTVIAVLGKGCSATSFGTVILYTSELYPTVVRQNGMGYTSFIARFGVSVAPLILLSNDVWSYF--SQVILCFLALSAAFVAYQLPETSGKCLPETIDDIEGIR--KDKNGLLLQDRKMEEKDNM-----EKLKDNL 466          

Query:  366 SILMNGTTMN-CKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINR--LRFDVEKDQIYVENLVKEGNICVACKD----TDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLL-LISNFLSFSGAVLINRLSVISYFLPTLIY--FSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLK 1625
            SI  N T ++ C E W F+     +T+V++F LVC++ +L D+  +     F +G  V G+++DRFGRK+  I S+     S   +  SP +   L FR L G  A   + +  V +IE      R F+      ++++  ++ P  ++    WR  QL   +P+ +F ++ + +PESPRWL    +  E +  ++ ++K N+  L  D  +  + +E   +E  +  + KD       +  + + ++  F+  +++  +++ +GI   N++L   +  ++ELP+ L+ Y+++  I R+     +  +G        F S +I   S +R  +  + ++A++  N+ +     EL+PT  R+ G+++    S+  +     ++ RL+ I   LP L+Y   S L+  G+V+   LPE K + +PET+ D++ L+
Sbjct:  101 SIFNNSTHLSACNEGWTFN--ENRTTIVTEFSLVCEDSWLADLNQVSLAGGFFIGALVTGYLADRFGRKSCFIASIFGLGVSGTCIIFSPYYPLLLFFRCLQGFFAKGAWTATYVLIIEFFGSNNRKFVSVMSRTFYSLGLVLLPALAYYIPSWRNLQLAMTLPTFIFLIYHWVIPESPRWLLSQRKTKEALSIVKSIAKCNKRSLPEDFHEMDLLIEK--QEEIMRPSYKDLFKTPKMRKHTFILIYAWFTGAVVFQGLVLRLGITGDNVFLDFLISAVVELPTGLIFYFLVDRIGRRPLMATVNFIGGAACLAVPFISPNI---SWLRRTIAIVGRLAVAIGNETVNFANTELYPTPLRNLGVSVCSSASDIGAVVAPFILYRLASIWQELPLLVYGVMSVLY-SGLVML--LPEMKGVDLPETVDDVENLR 524          

Query:  393 NCKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLI-ESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFF-MPESPRWLCVMNRKDEMMESLRFMSKIN---------RLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLK 1625
            NCK+ WD++    GS+LV++F LVC + +  D         F +G  + G+++DRFGRK  +I S+++     IL+A +PN+   +TFR + G  +   ++S   L+ E V +E R  +G  Y   +TV  ++    +++   WR  Q+   IP  F+L  ++ +PESPRWL   NRK E    +  ++K N          L  D E  +  V + +         +    +  +++ ++  F+  ++Y   ++ +G  + N+Y   F+  L+E PS +L    +  + R+  +L+   +  +   I+ F        S + I L C+S++ I+   + + +   EL+PT  R+ GI  ++ S+     G +   ++ RL+ I   LP +++     + G++VYF LPETK   +PET+ + + L 
Sbjct:  112 NCKDGWDYNT--TGSSLVTEFNLVCGDSWKLDFFQSCVNIGFFIGGLISGYIADRFGRKPFLISSILITGIFGILMAFAPNYPLVVTFRFIQGFVSKGCWLSGYILVAEFVGLEHRRTVGIVYQAAFTVGLLLLSGVAYVLPHWRWLQMTVTIPYFFFLAYYWCVPESPRWLISQNRKAEAKAIIHTIAKKNGKMVPDFLESLTADEEAGEKQVPSFLD------LVRTPQIRKHTLILMYIWFTCAVVYQGSIMHMGSTAENIYFDFFISALVEFPSAILIIVTVDRVGRRYPWLVCCIITGITCLITAFIPHG---YSWLIITLSCVSRMGITVSYEMVCLVNAELYPTFIRNLGI--MVCSSMCDLGGVITPFIVYRLAAIWQELPLIVFAVLATVSGILVYF-LPETKGRALPETIEEAENLH 524          

Query:  219 FKIVAFFILSLPTFQSCSQ--IQNILFALFIPNFKCRFNSKSKFIVSKDQCS-------ILMNGTTMNCKE-----------------------------WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLI-ESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIP-SVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDF------QSRSIMALFCA-----FSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSG--AVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMK 1616
            F+I    +L  P     S   +QN  F+  IP+ KC+ N       S D+         +  NG    C E                             W++S     ST+++++ LVC  +    +   ++    L+G  + G +SDR+GR+ ++I S      S +  A SPN+ +Y  FR L G++ S + ++   LI E V    R   G+   F +T   ++    ++  RDWR  QL   +P  +++L+ ++ PES RWL +  + ++ ++ +R ++ +N  + + EK  I +E+L  E    +A   + +      ++ +I  + CA     FS +  Y  + +D+   + ++YL   + G ++ P+ L+S   + Y+ RK    +   +G + +  +IF    +     +R  L    K  +++    I +Y  EL+PT  R  G  L + S      G  A L+  L  +  F+P LIY     I G+ V+F LPET + P+P+T+ + K
Sbjct:   16 FQITQVVLLCFPILLMASHNLLQN--FSAAIPDHKCKANDTGYQSNSTDETGYERLSAPLDANGQPDRCLEYVEIQWRMVGSNSTWNNSSELATRPCTIGWEYSKDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEK--ITLESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKFTQFMSLILGGIAIIANIFVPNEL---QTVRTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSG--LGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVFF-LPETVNKPLPDTIEEHK 525          

Query:  219 FKIVAFFILSLPTFQSCSQ--IQNILFALFIPNFKCRFNSKSKFIVSKDQCS-------ILMNGTTMNCKE-----------------------------WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLI-ESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIP-SVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDF------QSRSIMALFCA-----FSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSG--AVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDM-KMLKCGKEE 1640
            F+I    +L  P     S   +QN  F+  IP+ KC+ N       S D+         +  NG    C E                             W++S     ST+++++ LVC  +    +   ++    L+G  + G +SDR+GR+ ++I S      S +  A SPN+ +Y  FR L G++ S + ++   LI E V    R   G+   F +T   ++    ++  RDWR  QL   +P  +++L+ ++ PES RWL +  + ++ ++ +R ++ +N  + + EK  I +E+L  E    +A   + +      ++ +I  + CA     FS +  Y  + +D+   + ++YL   + G ++ P+ L+S   + Y+ RK    +   +G + +  +IF    +     +R  L    K  +++    I +Y  EL+PT  R  G  L + S      G  A L+  L  +  F+P LIY     I G+ V+F LPET + P+P+T+ ++ K +   K+E
Sbjct:   16 FQITQVVLLCFPILLMASHNLLQN--FSAAIPDHKCKANDTGYQSNSTDETGYERLSAPLDANGQPDRCLEYVEIQWRMVGSNSTWNNSSELATRPCTIGWEYSKDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEK--ITLESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKFTQFMSLILGGIAIIANIFVPNEL---QTVRTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSG--LGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVFF-LPETVNKPLPDTIEEVEKGINAPKKE 534          

Query:  219 FKIVAFFILSLPTFQSCSQ--IQNILFALFIPNFKCRFNSKSKFIVSKDQCS-------ILMNGTTMNCKE-----------------------------WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLI-ESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIP-SVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDF------QSRSIMALFCA-----FSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSG--AVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMK 1616
            F+I    +L  P     S   +QN  F+  IP+ KC+ N       S D+         +  NG    C E                             W++S     ST+++++ LVC  +    +   ++    L+G  + G +SDR+GR+ ++I S      S +  A SPN+ +Y  FR L G++ S + ++   LI E V    R   G+   F +T   ++    ++  RDWR  QL   +P  +++L+ ++ PES RWL +  + ++ ++ +R ++ +N  + + EK  I +E+L  E    +A   + +      ++ +I  + CA     FS +  Y  + +D+   + ++YL   + G ++ P+ L+S   + Y+ RK    +   +G + +  +IF    +     +R  L    K  +++    I +Y  EL+PT  R  G  L + S      G  A L+  L  +  F+P LIY     I G+ V+F LPET + P+P+T+ +++
Sbjct:   16 FQITQVVLLCFPILLMASHNLLQN--FSAAIPDHKCKANDTGYQSNSTDETGYERLSAPLDANGQPDRCLEYVEIQWRMVGSNSTWNNSSELATRPCTIGWEYSKDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEK--ITLESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKFTQFMSLILGGIAIIANIFVPNEL---QTVRTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSG--LGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVFF-LPETVNKPLPDTIEEVE 525          

Query:  219 FKIVAFFILSLPTFQSCSQ--IQNILFALFIPNFKCRFNSKSKFIVSKDQCS-------ILMNGTTMNCKE-----------------------------WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLI-ESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIP-SVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDF------QSRSIMALFCA-----FSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSG--AVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMK 1616
            F+I    +L  P     S   +QN  F+  IP+ KC+ N       S D+         +  NG    C E                             W++S     ST+++++ LVC  +    +   ++    L+G  + G +SDR+GR+ ++I S      S +  A SPN+ +Y  FR L G++ S + ++   LI E V    R   G+   F +T   ++    ++  RDWR  QL   +P  +++L+ ++ PES RWL +  + ++ ++ +R ++ +N  + + EK  I +E+L  E    +A   + +      ++ +I  + CA     FS +  Y  + +D+   + ++YL   + G ++ P+ L+S   + Y+ RK    +   +G + +  +IF    +     +R  L    K  +++    I +Y  EL+PT  R  G  L + S      G  A L+  L  +  F+P LIY     I G+ V+F LPET + P+P+T+ +++
Sbjct:   16 FQITQVVLLCFPILLMASHNLLQN--FSAAIPDHKCKANDTGYQSNSTDETGYERLSAPLDANGQPDRCLEYVEIQWRMVGSNSTWNNSSELATRPCTIGWEYSKDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEK--ITLESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKFTQFMSLILGGIAIIANIFVPNEL---QTVRTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSG--LGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVFF-LPETVNKPLPDTIEEVE 525          

Query:  408 DFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVA-CKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKML------KCGKEEE 1643
            D+  +   ST+VS F LVC N ++ D+   +    FL G F +G+ +DR+GR  I ++S      + +++A +PNF+ ++ FR L G+     +++  V + E V  + R  +G     ++T+  ++ P  ++    W+  QL   +PS +F L+ + +PESPRWL    + ++ ++ LR ++K N         +I V +       C+   +    +  +++ +F  F+  ++Y  +++ +G++  N+Y+  F+ GL+ELP  LL    +  + R++ F     V  +   ++ F  + IP    +R  +  L ++ I+   + + +  +EL+PTT R+FG++  L S    F G +   L+ RL+ I   LP +I+     + G +V   LPETK + +PET+ D++ L      +CG++++
Sbjct:  125 DWRYVETHSTIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIIYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNYSEITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIGGNLYIDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEGIPW---LRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVS--LCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILASVCGGLVML-LPETKGIALPETVEDVEKLGSSQLHQCGRKKK 543          

Query:  180 LDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCR------------------FNSKSKFIVSKDQCSIL---------MNGTTMNCKE------WDFSLLPI------------GSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVY-ISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVE---NLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDM-KMLKCGKEEEFVFYMQNK 1667
            +D+IL  I +   F+   FF+L+L +         I+F  F PN  CR                   N     + S  + S L          N +T++C +       + S LP+            GS++V++F LVC + ++ D+   +    F +G   +G+++DRFGRK  +++++++   S +L+A+SPN+A  L FR L GL + A + I  + + E V + +R  +G  Y   +TV  ++    ++   +WR  Q    +P+  F L+ + +PESPRWL   N+  + M+ ++ ++K N     V    +  +    +    +     +    +  +++ ++  F+ +++Y  +++ +G+   N+YL  F   L+E P+  +    +  I R+  + +   V       S+F    +     ++I + CL ++ I+   + + +   EL+PT  R+  +  L+ S+     G V   L+ RL+ I    P L+ F+ + +V   +   LPETK   +PET+ D  KM +  K++E   Y+Q K
Sbjct:    4 VDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPNHHCRSPGVAELSQRCGWSPAEELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYDTPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGVLMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVGICYQIAFTVGLLILAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVPVSLQSLTADEDTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAGAACLASVFIPDDL---QWLKITVACLGRMGITIAYEMVCLVNAELYPTYIRNLAV--LVCSSMCDIGGIVTPFLVYRLTDIWLEFP-LVVFAVVGLVAGGLVLLLPETKGKALPETIEDAEKMQRPRKKKEKRIYLQVK 548          

Query:  180 LDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCR------------------FNSKSKFIVSKDQCSIL---------MNGTTMNCKE------WDFSLLPI------------GSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVY-ISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVE---NLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLK 1625
            +D+IL  I +   F+   FF+L+L +         I+F  F PN  CR                   N     + S  + S L          N +T++C +       + S LP+            GS++V++F LVC + ++ D+   +    F +G   +G+++DRFGRK  +++++++   S +L+A+SPN+A  L FR L GL + A + I  + + E V + +R  +G  Y   +TV  ++    ++   +WR  Q    +P+  F L+ + +PESPRWL   N+  + M+ ++ ++K N     V    +  +    +    +     +    +  +++ ++  F+ +++Y  +++ +G+   N+YL  F   L+E P+  +    +  I R+  + +   V       S+F    +     ++I + CL ++ I+   + + +   EL+PT  R+  +  L+ S+     G V   L+ RL+ I    P L+ F+ + +V   +   LPETK   +PET+ D + ++
Sbjct:    4 VDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPNHHCRSPGVAELSQRCGWSPAEELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYDTPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGVLMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVGICYQIAFTVGLLILAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVPVSLQSLTADEDTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAGAACLASVFIPDDL---QWLKITVACLGRMGITIAYEMVCLVNAELYPTYIRNLAV--LVCSSMCDIGGIVTPFLVYRLTDIWLEFP-LVVFAVVGLVAGGLVLLLPETKGKALPETIEDAEKMQ 533          

Query:  180 LDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCR------------------FNSKSKFIVSKDQCSIL---------MNGTTMNCKE------WDFSLLPI------------GSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLI-ESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKE---GNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFL-------LIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSG---AVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKML--KCGKEEEFVFYMQ 1661
            +D++L  + +   F+  AF +L L +         I+F  F P+  CR                   N     + S  + S L          N +T++C +       + S LP+            GS++V++F LVC + +  D+        F LG  V G+++DRFGRK  ++++ ++ + S +L A++P++ + L FR+L G+ +   ++S   LI E V   +R      Y   +TV  +     ++   DWR  QL   +P+ +F L+ +F+PESPRWL    R  + +  +  +++ NR     +   + +E    E    +     +    +  +++ ++  FS  ++Y  +++ +G   +N+YL  F      L     ++ +L  I R IG +       L+ G   LL+   IF    +     + + L CL ++  +   Q + +   EL+PT  R+ G  +++ S      G     ++ RL  +   LP LI F  L +    V   LPETK + +PET+ + + L  +  K +E   Y+Q
Sbjct:    4 VDDVLEHVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPDHHCRSPGVAELSQRCGWSPAEELNYTVPGLGSAGEASFLSQCMKYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSLSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQVAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTQAVRIMEQIAQKNRKVPPADLKMMCLEEDASERRSPSFADLFRTPSLRKHTLILMYLWFSCAVLYQGLIMHVGATGANLYLDFF---YSSLVEFPAAFIILVTIDR-IGRIYPIAASNLVAGAACLLM---IFIPHEL---HWLNVTLACLGRMGATIVLQMVCLVNAELYPTFIRNLG--MMVCSALCDLGGIFTPFMVFRLMEVWQALP-LILFGVLGLSAGAVTLLLPETKGVALPETIEEAENLGRRKSKAKENTIYLQ 547          

Query:  282 NILFALFIPN------FKC-RFNSKS-KFIVSKDQCSILMNGTTMNCKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIV-WLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIP-SVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLV----------KEG-NICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRK---IGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNS 1700
            ++L A+ IP        +C RF     +   S    +   +  T  C++ W +      ST+V+ + LVC+++ L  +   ++ A  L+G  V G  SDRFGR+ ++  S +L + S    A  P F  Y  FR LL  + + V ++    L+E  S +  P + +     ++   ++    ++  R WR+ QL    P  +F+++ +++PES RWL  + + D+ ++ L+ ++ +NR +   E D + +E L           K G ++         + R+I+++ C F+    +  + +D+  L SN++L   L+G+++ P    S  ++  + R+   + FL++ G   L +  +I     +    V+R  L  L    +      I ++ +ELFPT  R   + L  ++         L+  L V   ++P L+Y     + G+     LPETK+LP+P+T+ D++              Q+  K  ++T D S
Sbjct:   70 DVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAATEPCEDGWVYDHSTFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMTLNALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNRRK--AEGDTLTMEVLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIISMLCWFAFGFTFYGLALDLQALGSNIFLLQALIGIVDFPVKTGSLLLISRLGRRLCQVSFLVLPG---LCILSNILVPHGM---GVLRSALAVLGLGCLGGAFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVLSGLAALL-LPETKNLPLPDTIQDIQ-------------KQSVKKVTHDTPDGS 546          

Query:  408 DFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVA-CKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKML------KCGKEEE 1643
            D+  +   ST+VS F LVC N ++ D+   +    FL G F +G+ +DR+GR  I ++S      + +++A +PNF+ ++ FR L G+     +++  V + E V  + R  +G     ++T+  ++ P  ++    W+  QL   +PS +F L+ + +PESPRWL    + ++ ++ LR ++K N         +I V +       C+   +    +  +++ +F  F+  ++Y  +++ +G++  N+Y+  F+ GL+ELP  LL    +  + R++ F     V  +   ++ F  + IP    +R  +  L ++ I+   + + +  +EL+PTT R+FG++  L S    F G +   L+ RL+ I   LP +I+     + G +V   LPETK + +PET+ D++ L      +CG++++
Sbjct:  125 DWRYVETHSTIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIIYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNYSEITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIGGNLYIDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEGIPW---LRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVS--LCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILASVCGGLVML-LPETKGIALPETVEDVEKLGSSQLHQCGRKKK 543          

Query:  408 DFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVA-CKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKML------KCGKEEE 1643
            D+  +   ST+VS F LVC N ++ D+   +    FL G F +G+ +DR+GR  + ++S      + +++A +PNF+ ++ FR L G+     +++  V + E V  + R  +G     ++T+  ++ P  ++    W+  QL   +PS +F L+ + +PESPRWL    + ++ ++ LR ++K N         +I V +       C+   +    +  +++ +F  F+  ++Y  +++ +G++  N+Y+  F+ GL+ELP  LL    +  + R++ F     V  +   ++ F  + IP    +R  +  L ++ I+   + + +  +EL+PTT R+FG++  L S    F G +   L+ RL+ I   LP +I+     + G +V   LPETK + +PET+ D++ L      +CG++++
Sbjct:  125 DWRYVETHSTIVSQFDLVCGNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIVYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNYSEITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIGGNLYMDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEGIPW---LRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVS--LCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILASVCGGLVML-LPETKGIALPETVEDVEKLGSSQLHQCGRKKK 543          

Query:  180 LDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCR------FNSKSKFIVSKD-----------------QC---SILMNGTTMNCKE------WDFSLLPIG------------STLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVY-ISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFF-MPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEG---NICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMK-MLKCGKEEEFVFYMQNK 1667
            +D+IL    +   F+   FF+L+L +         I+F  FIP+ +CR       + +  + ++++                 QC    +  N +T+ C +       + S LP+G            S++V++F LVC N +L D+        F +G   +G+++DRFGRK  ++L++++   S +L+A+SP +   L FR++ GL + A + I  + + E V + +R  +G FY   +T   +V    ++    WR  Q    +P+  +LF ++ +PESPRWL   N+  + M  ++ ++K N          +  +  V E    +     +    +  +++ ++  F+  ++Y  +++ +G+  SN+YL  F   L+E P+ LL    +  + R+  +     V       S+F  +       +RI + CL ++ I+   + + +   EL+PT  R+ G+  L+ S+     G +   L+ RL+ I + LP L+ F+ + ++   +   LPETK   +PET+ + + M +  K +E + Y+Q K
Sbjct:    4 VDDILEHTGEFNFFQKQTFFLLALLSAAFTPIYVGIVFLGFIPDHRCRSPGVAELSQRCGWSLAEELNYTVPGPGPAGQAFPRQCRRYEVDWNQSTLGCVDPLAGLAANSSHLPLGPCRYGWVYDTPGSSIVTEFDLVCANSWLLDLFQSAVNVGFFIGSVGIGYIADRFGRKLCLLLTILINAVSGVLMAISPTYTWMLVFRLIQGLVSKAGWMIGYILITEFVGLSYRRTVGIFYQVAFTFGLLVLAGVAYALPHWRWLQFTVTLPNFCFLFYYWCVPESPRWLISQNKNAKAMSIIKHIAKKNGKSLPASLQSLRPDEEVGEKLKPSFLDLVRTPQIRKHTLILMYNWFTSAVLYQGLVMHMGLAGSNLYLDFFYSALVEFPAALLILLTIDRLGRRHPWAASNVVAGAACLASVFIPED---PHWLRITVLCLGRMGITMAYEMVCLVNAELYPTFIRNLGV--LVCSSMCDIGGIITPFLVYRLTDIWHELP-LVVFAVVGLIAGGLVLLLPETKGKTLPETIEEAETMRRPRKNKEKIIYLQVK 547          

Query:  432 STLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYV-ENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKML------KCGKEEE 1643
            ST+VS+F LVC N ++ D+   +    FL G F +G+ +DR+GR  I +LS +    + +++A +PNF  ++ FR L G+     +++  V + E V  + R  +G     ++T+  ++ P  ++   +W+  QL   +PS +F L+ + +PESPRWL    + D+ ++ LR ++K N         +I V +  V   +     +    +  +++ +F  F+  ++Y  +++ +GI+  N+Y+  F+ G++ELP  LL    +  + R++ F     V  +   ++ F  + I   + +R  +  L ++ I+   + + +  +EL+PTT R+FG++  L S    F G +   L+ RL+ +   LP +I+     I G +V   LPETK + +PET+ D++ L      KCG+ ++
Sbjct:  138 STIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFLPEGI---AWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVS--LCSGLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVML-LPETKGIALPETVDDVEKLGSPHSCKCGRNKK 548          

Query:  180 LDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSKSKF------------------IVSKDQCSIL---------MNGTTMNCKE------WDFSLLPIG------------STLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVY-ISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYV-ENLVKEGNICV--ACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMK-MLKCGKEEEFVFYMQNKH 1670
            +D+IL  I +   F+   FF+L+L +         I+F  F P+  C     +K                   +   D+ S L          N +T++C +       D + LP+G            S++V++F LVC + ++ D+   V    F +G   +G+++DRFGRK  +++++++   S  L+A+SPN+A  L FR L GL + A + I  + + E V + +R  +G  Y   +TV  ++    +++  +WR  Q    +P+  F L+ + +PESPRWL   N+  + M+ ++ ++K N     V    +   E+  K+ N       +    +  +++ ++  F+ +++Y  +++ +G+   N+YL  F   L+E P+  +    +  + R+  + +   V       S+F    +     ++I + CL ++ I+   + + +   EL+PT  R+ G+  L+ S+     G +   L+ RL+ I    P L+ F+ + +V   +   LPETK   +PET+ D + M +  K++E   Y+Q K 
Sbjct:    4 VDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPDHHCWSPGAAKLSQRCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLAADRNQLPLGPCEHGWVYNTPGSSIVTEFNLVCAHSWMLDLFQSVVNVGFFIGAMMIGYLADRFGRKFCLLVTILINAISGALMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRMVGICYQIAFTVGLLILAGVAYVIPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKIVKAMKIIKHIAKKNGKSVPVSLQNLTPDEDAGKKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRVGRRYPWAVSNMVAGAACLASVFIPDDL---QWLKITIACLGRMGITMAYEMVCLVNAELYPTYIRNLGV--LVCSSMCDIGGIITPFLVYRLTDIWMEFP-LVVFAVVGLVAGALVLLLPETKGKALPETIEDAENMQRPRKKKEKRIYLQVKQ 549          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSKSKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSKLITGKNK 1760
            MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKC+FNSKSKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGP VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSI ALFCAFSINLIYSSMLVDIGILSSNMYLSVFLLGLMELPSLLLSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSKLITGKNK
Sbjct:    1 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCKFNSKSKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPLVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSITALFCAFSINLIYSSMLVDIGILSSNMYLSVFLLGLMELPSLLLSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSKLITGKNK 529          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSK-SKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSKLITGKN 1757
            M L++IL D NK  TFK +AFFILSLP+FQ  SQ+QNIL + + P + C +NS  SK  +S DQC+++++G+T+ C +W+FS  P+G T++SDF LVCD + LGD+IL+VWY+  + GP +G+ SD+FGRK + I +L LET S+  ++ +P+  + +  R+L+G+SA+  Y   VWL+E V  EFR F GSF W Y  +AYMVFP+T++  +DWR++QL +LIP++ Y  I   PESPRWLCV NRK E+++SL  +++IN++  ++  DQI+V     E N   A KD  F  R  ++    FSINLIY+++ V++ ILS+NMY+S+FLLGLME P +LLSY  LR+ +RK  F+LIGG+GS+ + IS+FFS++I  Q VIRI+ GC++KIA+++CNQ+ MVYV+EL PT+HRS G   + ++N  SF+ AV IN+LS + +FLP +IYF  +++   ++Y  LPETK+LPIPETL+D KMLK  KE+EF+ YM  K +    +  + D   S    E+S LI  K+
Sbjct:    1 MILEDILKDYNKRNTFKFLAFFILSLPSFQFSSQMQNILISTYTPKYTCLYNSSFSKISISADQCNMIIDGSTIVCNKWNFSYEPVGRTMMSDFSLVCDYKNLGDIILIVWYSTSITGPIMGWFSDKFGRKKVAIFNLCLETISTFFVSFTPDVTSNIICRLLIGISANGFYTCYVWLMEMVDNEFREFSGSFIWTYGCLAYMVFPLTAYFTKDWRITQLISLIPNILYFLILLFPESPRWLCVTNRKSELIKSLNKIAEINKIDTNINYDQIFVPKTKDEHNTWKALKDKTFSLRMTLSFLLVFSINLIYAAIAVNLQILSNNMYISMFLLGLMEFPGILLSYVSLRFFRRKTSFILIGGIGSIFILISVFFSRNILWQGVIRIIFGCIAKIAVTTCNQSTMVYVSELCPTSHRSLGFASIQLANLCSFTAAVYINKLSTVLFFLPMVIYFILMFLTSCIIYLYLPETKNLPIPETLLDQKMLKVNKEKEFLDYMNKKREMEVESDLDLDLLKSNESTEESHLINRKH 529          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSKSKFI-VSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSKLITGK 1754
            M L+N++S  NK  TFK++AF ILSLP FQ  SQ QN+L ++  PNF C++N  S  I +SKDQC++ +NG+ + C+ W FS  P G T++SD+ LVCD +Y+GD+++++WY+  L+ P  G+++D++GRK I I+ L +ET ++ +LA +PN ++++ FR+ +G S SA +I  VWL+E V+ +FR   GSF+W Y +VA  VFP+T ++ R+WRL+QL +L PS+ Y+ I F+PESPRWLCV N+K ++MESL+ ++ IN++   +  ++I +E   KE N   A KD +F   +  +LF  FSI+++ S++L+D+ +LSSN+Y+S+F+LGLME P  LLSY  + + KRK    +    GS+ +F+S+  SK    QS+ R++ G + K+ + + +Q ++VY  ELFPTTHRS    +L I   ++ + AV IN+L+    F+P LIYF    I   +++  +PETK LPIPET+ D ++L   +E+E++ YM N+     + V NSD + S+  +E S+LI  K
Sbjct:    1 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPEEIKIEKTTKESNKWNAFKDNNFLFLASTSLFAVFSISILISAILIDLNLLSSNIYISMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNR-----SDVVNSDREDSDASSEMSQLINRK 523          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCR---FNSKSKFIVSKDQCSILM---NGT--TMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMAL------FCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLL--ISNFLSFSGAVLINRLSVISYFLPTLIYFS------FLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFN 1682
            M  +  +S+I     F ++A   LS+    S   I +I+F    P++KC    FN +++   +  +C  +    NGT  T+ C+ W ++   + +T+ ++F LVC+ +    ++  +++    +G F+    D+ GR  ++ L+++ E   +I L  + N    +  R L GL    +Y  + +L E VSI+ R    + YW  + + YM+ P  ++  +DWRLS+     P +FYL  F +PESPRWL +  +  + + +L  ++K N   F   K    +    K GNI      TD     IM L      F   +I++ Y  + ++   LSSN++L+VF+ GL+E  +  +++ +   + R++  L+   + S+ L ++ F+S +  + S++   LG + K A+++      +Y+NE+FPT  R+  I ++L   S F  F+ ++     + I  F+P   YFS         I G+++YF LPETK  P+P+TL +   L+ G E  +   +    + +N
Sbjct:    1 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFN-QTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNFPLLFYLTYFLLPESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNI------TDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFNNIIVSIVISTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSI-----NGIDEFIP---YFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCNMILKHDELYN 510          

Query:  387 TMNCKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYIS-IVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYL-FIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENL-VKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSV-IRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSD 1703
            T  C+E W++      S  V++F LVC + +L D+        FL+G   +G+++DRFGRK   ++S VL + + +L+A++PN+ + L FR   GL     +++  V + E V +EFR  +G FY  +++V  ++ P+ ++   DWR  Q+   +P + +L + +F+PESPRWL   N+K + ++  R M+K N+     + + +  +N      +     +    +  + +  F  F+  ++Y  +++ +GIL  N+Y+   + GL+E P+  L  + +  I R++ F       +++  +S F +  IP     ++ V+ C+ ++ I+   + ++    EL+PT  R+FG++  + S      G V   L+ RL+VI   LP +I+    ++ G +V   LPETK +P+P+T+ D++  +  K++  +   Q  +   N+   N D
Sbjct:   14 TSGCREGWEYDYRGRQS-FVTEFDLVCSDGWLVDLYQSTLNVGFLVGSIAIGYLADRFGRKVTFLMSNVLNSIAGMLVAVAPNYVSLLVFRTFYGLGVKGGWVAGYVLITEIVGVEFRRTVGVFYQMFFSVGILLLPLLAYFITDWRWLQVAITVPYIVFLSYYWFIPESPRWLLSQNKKSKAVKITRDMAKENQRSLSKKIETLSDDNADSTTASFMDLVRTPKMRKHTFILSFNWFTSAVVYQGLIMRLGILGGNVYIDFLISGLVEFPAAFLILFTIERIGRRLPF----ATANIVAGVSCFVTALIPDDMFWLKTVVACVGRLGITMTFEMVVFVNTELYPTFVRNFGVS--VCSTLCDVGGIVAPFLLYRLAVIWLELPLIIFGILAFLAGGLVLL-LPETKGVPLPDTIDDVEFPERAKQKVELRSQQLDNLLSNDVSSNKD 453          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCR--------FN-----SKSKFIVSKDQCSILMNGTTMNCKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYI-SIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRL-----RFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSIN-LIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKR--KIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEE 1643
            M  D +L+ I     F+ + +  + LP       +   +F   +P   CR        FN     S S+   S    S L   TT  C++ W+FS     ST+V++F LVCD+  L ++   ++    L+G  V G ++DR+GR+ I+++ L L+    +  A +PNF  Y+  R ++G + S + + + V   E    + R   G    +++ V Y++    ++L RDWR  QL    P  +F  +I+ +P+S RWL    +++E M+ +   + IN+        + + +   VE  ++  +  V    T    +  + LF  + +N L+Y  + +++     N+YL+  + GL+E+P+  ++ + L   +R  ++ FL +GG+  LL   +IF  +++P   V+R +L  L K  I++    + VY  E+FPT  R  GI +    +  + +G V   +I  L  IS   P ++ F    +VG ++   LPET   P+P+T+ D++      E +
Sbjct:    1 MNFDEVLARIGGFGRFQKILYVWICLPQIFLAFHMLVSVFTGAVPPHLCRDTKTHTHNFNFTLSQSASEACGSTHTNSSLSTHTTTACRDGWEFSKDVFLSTVVTEFDLVCDSATLNNIGSSIYMFGLLVGAVVFGVLADRYGRRIIILVGLALQAMFGVGAAFAPNFFIYVLLRFVVGTTVSGIIMNAFVLGTEWTGPKHRMLAGIITDYFFGVGYILLAGVAYLIRDWRKLQLAISAPGFIFIFYIWVLPKSARWLMANGKQEEAMDLICKAALINKKPLKGNDMEFQLNNCKVEQKLQRKHTVVDLVRTPQMRKQSLILFYLWFVNVLVYYGLSLNVSDFGMNIYLTQLIFGLVEMPARTITLFTLNRSRRISQLSFLAVGGLACLL---TIFIPQNLP---VVRTILAMLGKFGITASLSIVYVYSAEVFPTVVRQNGIGM---GSMCARAGGVIAPIIYLLRRISPHAP-MVVFGLCPLVGALLTILLPETAHKPLPDTIEDVEGTSNKAETQ 508          

Query:  183 DNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRF--------------NSKSKFI---------VSKDQCS---ILMNGTTMNCKEWDFSL-------LPIGS-------------TLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYL-FIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENL-VKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEE 1640
            D+IL +  K   F+   F +L + +         ++F  F P   C+                   +FI         V   QC    +  N T +NC   D          LPI +             + V++F LVCD+ +L DV   V    FL+G   +G+++D+FGRK   +LS +L   + IL+A+SPN+ + + FR L G      +++  V + E+V + F+ F  SF      +   + P       +WR  Q+   +P + +L + +F+PESPRWL   N+    +E  + M+K N+         +  +N     G+     +    +  +++  F  F+  ++Y  +++ +GIL  N+Y+   + G++E P+  L  + +  I R++ F     V      I+ F  +S+     ++  + C+ ++ I+   + ++    EL+PT  R+ G++  + S      G +   L+ RL+VI   LP +I+    ++ G +V   LPETK +P+PET+ D++     KE+
Sbjct:    5 DDILEEAGKFGRFQKRIFGLLCMVSLPFAGVYVGVVFQGFTPEHWCQDPGLEQLQKHCGLGPEKARQFIIPLVNSSAGVGPSQCQRYDVDWNSTDLNCDGLDSETTEVQRAGLPITACKNGWHYDYEHRESFVTEFDLVCDDAWLVDVFQAVLGIGFLVGSITIGYLADKFGRKMSFLLSNILNAVTGILVAISPNYISLVVFRALHGFGVKGGWMAAYVLMTETVGVLFQMFF-SFGLLLLALIAYLIP-------NWRWLQVAFTVPYIIFLSYYWFVPESPRWLLSQNKSSRAVEVTQAMAKENKKTLSQNIKNLKDDNAETSTGSFMDLIRTPKIRKHTLILSFNWFTSAVVYQGLIMRLGILRGNIYIDFLISGIVEFPAAFLILFTIERIGRRLPFAAANIVSGAACLITAFIPESVLW---LKTAVACIGRLGITMAFEMVVFVNTELYPTFIRNLGVS--VCSTLCDIGGIIAPFLLYRLAVIWLELPLIIFGVLAFVAGGLVLL-LPETKGVPLPETIDDIEYPNRNKED 529          

Query:  366 SILMNGTTM-NCKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINR--LRFDVEKDQIYVENLVKEGNICVACKD----TDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLL-LISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEE 1640
            SI  N T + +C E W F L    +T+V++F LVCD  +L D+      A F +G FV G+++DRFGRK   I S++    S I L +SPN+  +L FR L G  A   + +  V +IE      R F+       ++   ++ P  ++    W+  QL   +P  +F ++ + +PESPRWL    R  E M  ++ ++K N+  +  D ++  + VE   ++  +  + KD       +  +I+ ++  F+  +++  +L+ +GI   N++L  F+  ++ELP+ L+ Y ++  + R+        V  L   I  F +++I   S +R ++  + ++A++   + +    +EL+PT  R+ G+++    S+  + +   L+ RL+ I   LP  +Y     +   +V   LPE K + +PET+ D++    GKE+
Sbjct:  107 SIPTNTTPLTSCDEGWTFDL--TWTTVVTEFVLVCDRSWLADLNQATLAAGFFIGAFVSGYIADRFGRKLCFIGSMLGLGVSGICLIISPNYPLFLVFRCLQGFFAKGAWTTTYVLVIEFFGSNNRKFVSVMTRTLYSTGMVLIPGLAYYIHSWKYLQLTMTLPIFIFLVYYWAIPESPRWLLSQKRTKEAMIVIQNIAKCNKRSVPADFQEMDLLVEQ--QQEIVHPSFKDLFRTPKMRKHTIILIYAWFTSTVVFQGLLLRLGITGDNLFLDFFISAVVELPTGLIFYLLVDRVGRRPLIATANLVAGLACLIVPFVTQNI---SWLRRIIAIIGRLAVAIGFETVNFANSELYPTPLRNLGVSVCSSASDIGAVAAPFLLYRLASIWQELPLFLYGVMSLVYSGLVTM-LPEMKGVDLPETIDDVE--NRGKED 533          

Query:  366 SILMNGTTM-NCKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINR--LRFDVEKDQIYVENLVKEGNICVACKD----TDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLL-LISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMK 1616
            SI  N T + +C E W F L    +T+V++F LVCD  +L D+      A F +G FV G+++DRFGRK   I S++    S I L +SPN+  +L FR L G  A   + +  V +IE      R F+       ++   ++ P  ++    W+  QL   +P  +F ++ + +PESPRWL    R  E M  ++ ++K N+  +  D ++  + VE   ++  +  + KD       +  +I+ ++  F+  +++  +L+ +GI   N++L  F+  ++ELP+ L+ Y ++  + R+        V  L   I  F +++I   S +R ++  + ++A++   + +    +EL+PT  R+ G+++    S+  + +   L+ RL+ I   LP  +Y     +   +V   LPE K + +PET+ D++
Sbjct:  107 SIPTNTTPLTSCDEGWTFDL--TWTTVVTEFVLVCDRSWLADLNQATLAAGFFIGAFVSGYIADRFGRKLCFIGSMLGLGVSGICLIISPNYPLFLVFRCLQGFFAKGAWTTTYVLVIEFFGSNNRKFVSVMTRTLYSTGMVLIPGLAYYIHSWKYLQLTMTLPIFIFLVYYWAIPESPRWLLSQKRTKEAMIVIQNIAKCNKRSVPADFQEMDLLVEQ--QQEIVHPSFKDLFRTPKMRKHTIILIYAWFTSTVVFQGLLLRLGITGDNLFLDFFISAVVELPTGLIFYLLVDRVGRRPLIATANLVAGLACLIVPFVTQNI---SWLRRIIAIIGRLAVAIGFETVNFANSELYPTPLRNLGVSVCSSASDIGAVAAPFLLYRLASIWQELPLFLYGVMSLVYSGLVTM-LPEMKGVDLPETIDDVE 527          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCR----FNSKSKFIVSK-DQCSILMNGTTMN------CKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYI-SIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLF-IFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVA--CKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKR--KIGFLLIGGVGSLLLFISIFFSKSIPLQSV-IRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVL---INRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEE 1643
            M  + +L+       F+   +  + LP  Q    +   +F    P  +CR     NS +       D CS    G+  N      C+  W +S     ST V+++ LVC    L  +   ++    L+G  V G M+DR+GR+  ++LSL L+T   +  A +PNF  Y+  R L+G + S + I + V   E  S + R   G F  +++ + YM+    ++L RDWR  QL    P   ++F I+ +P S RWL V +RK+E +  LR  + +N   F       + +         VA   +  + + R+++  +  F   L+Y  + + +  L +++Y + F+ GL+E+P+  L   VL   +R     FL IGG   LL+        ++P  +  I+  L    K  I++    I +Y  ELFPT  R  GI    +S+  +  G VL   IN L   +  +P LI+ S   ++G  +  +LPET + P+P+T+ D +     K ++
Sbjct:    1 MNFEQLLAAAGGFGRFQKTLYVWICLPQVQLAFHMMVSVFTGATPPHRCRSLRLANSSAGISAGHADACSA---GSAENRSARSACESGWVYSQDVFESTTVTEWDLVCGRASLNSICSSIYMLGLLVGAVVFGAMADRYGRRFALLLSLALQTVFGVAAAFAPNFLVYVILRFLIGTTISGIIINAFVLGTEWTSTKRRMLAGIFTDYFFGLGYMLLAGIAYLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNDRKEEAIVLLRKAAMVNGRSFPTTVQLDWCDETEGRSQHSVADLVRTPEMRKRALILYYIWFVNVLVYYGLSLGVSGLGTDLYFTQFMFGLVEVPARSLVLLVLPCSRRIPLSAFLFIGGGACLLML-------AVPADNPNIQTALAMTGKFGITASFAIIYIYSAELFPTVLRQTGIG---VSSMFARMGGVLAPMINLLGQHNPVVPVLIFGSTP-LLGAALALALPETANKPLPDTIQDAERFSNEKYDQ 499          

Query:  183 DNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSKSKFIVSKD------------------------QC---------------------------SILMNGTTMNCKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGP-FVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKIN--RLRFDVEKD-QIYVENLVKEGNICVA--CKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGI-TLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKY-FNNTVDNSDEKSS 1715
            D++L  I +   F+   F +L LP      Q  NI+F   +P  +CR  ++++   S+                         QC                           ++  +G  + C   W+F     G TLVS+F LVC+N +L D+   +     L+G   +G++SDR+GR+  +++S+V++T   +L+A +PN+A ++  R L G+     + ++ V   E V    R  +      +++   ++    ++  R WR  QL   +P+ V + + + +PESPRWL   NRK++    L+ ++ +N   L  ++ K+ +       K GN  +A   +    +  +++ +   F + ++Y  + +  G +  ++YL+  + GL E+P  L+   ++  + R++   +  G+  L    +      I   ++  + LG   ++ ++   + + +  NEL+PT  R+  + T   +S         ++ RL  I   LP +I F  L I+G  V   LPET  LP+PET  D + +   K ++    M    K+   N + N D ++ 
Sbjct:    5 DSLLQGIGEFGPFQHRVFAMLCLPCTLFAFQYLNIVFLGQVPEHRCRLPTETRRTSSRCGASLEAAHRNRSRASGSLEDQWNLQCMRVNTTTWSDSNAPCGLAPWGQGDEVPNVSFSGRLIACDHGWEFDTEKTGLTLVSEFDLVCENAWLLDLSQALLNVGLLVGAILMGYVSDRYGRRWSLMVSIVMQTIFGVLVAFAPNYAAFVCMRTLQGIFNMGSWTTVFVTATEFVGSGQRRVVHMVLQMFFSFGVIMLSGIAYYLRTWRYLQLALTLPNVVLFSYYWLLPESPRWLISQNRKEQAFGVLKKIASVNGRELSDNIRKNFEEVTRADEKAGNPSIADLMRSAKIRKYTVVLMIYWFVVGVVYQGLAMSTGNIGDDVYLAFLMGGLAEIPGALMVIALIDRVGRRLPMCVAPGLSGLACLATALVPHDIGWLNITLVTLG---RLGLTMAYEMVTLVNNELYPTHLRNMAMSTCSSLSGIGGIVAPFVLYRLYTIWRHLPMVI-FGTLAIIGGFVILLLPETNGLPLPETTEDAENIS--KNQKMKQKMLRSRKFETKNPLRNEDSQAD 571          

Query:  405 WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWL-IESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFI-FFMPESPRWLCVMNRKDEMMESLRFMSKIN-RLRFDVEKDQIYVENLVKEGNI 1022
            W++       T+V+ + LVC+++ L  + L ++ A  +LG  V G++SDR+GR+N ++ S VL   +    A +P+F+++   R LLG+S S + ++ + L +E +    R F G+   F W+   M   + ++L R W+  QL    P  F +   +F+PESPRWL V  R  E   +L   ++IN R +F  E   + VE     G+I
Sbjct:  115 WEYDRRQFTETVVTQWDLVCEHKALNHLSLTLFMAGVMLGSLVFGYLSDRYGRRNALLGSYVLNAVTGTAAAWAPSFSSFTAMRFLLGVSLSGIIVNTLSLSVEWLDQGHRTFAGTSGGFAWSTGNMALGLLAYLLRGWQQLQLVVTSPIYFCILTWWFIPESPRWLLVRGRAREAHRNLSLCARINGRTKFGSE---VTVEARGWHGSI 321          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCR-------------------FNSKSKFIVSKDQCSILMN--GTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLG-PFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYI-SIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYL 860
            M  D++L  I     F+++ +  + LP       +   +FA   P   CR                     S +     + +C   +N  G       WD+      ST+V+++ LVC   YL +V   ++    ++G P +G M+D++GRK+++++S+ ++T   +  A +PNF  Y   R ++G++ S V + + V   E   I  R   G      + V YM+    ++  RDWR  QL   IP + ++
Sbjct:    1 MNFDDVLKKIGGFGKFQMILYTWICLPHISIAMHMLVSVFAGATPAHFCRDPPGGHAPVPSATTAPPTAGESAAANGTERPRCGSRLNESGWQPCATGWDYDRSVFTSTVVTEWDLVCTRSYLNNVGSSIFMLGLMVGAPVLGTMADKYGRKSVILVSMAIQTAFGLGAAFAPNFVMYALARFMVGVAISGVIMNAFVLATEWTGIGERMLAGIATQQAFGVGYMLLAPVAYFIRDWRQLQLAISIPEILFI 252          

Query:  531 VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYI-SIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFF-MPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENL-----VKEGNICVACKDTDFQSR-SIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRK--IGFLLIGGVGSLLLFISIFFSKSIPLQ---SVIRIVLGCLSKIAISSCNQNIMVYVNELFPTT-------HRSFGITLLLISNFLSFSGAVLINRLSVI 1496
            +G  SDR+GR+ +++  +  +  +  ++A  PNF TYL  R+L G +AS + + S    +E      R +        ++V  M     + ++++W    L T +P +  L +F+ +PESPRWL +  R  E    LR  S INR R +V    + + +        E  + +  ++   + R  IM+  CA ++++ Y  + + +G    +++++ FL GL E+P LLL   + R  +R   I FL + G   LL          +PLQ   + + + L  L K+          +Y  ELFPT        HR   +  + +   +    A L+NR +++
Sbjct:   36 MGIASDRYGRRPVLLGCVASQGAAEFVIAFLPNFPTYLLGRLLTGTTASGIMLCSFSLGVEWCGPALRAWPPIILALAFSVGMMALAGVAKISQNWPQLHLATGVPQLMVLLLFWSLPESPRWLFLKKRTTEARNLLRQASIINR-RSEVSWTPLRLTSKLSTRGANESTLLITFRNRTLRKRLLIMSYICA-AVSMTYYGLCLSVGDFGLDIHMAQFLSGLAEIPQLLLPPLMRRVGRRSLCIVFLSVAGATCLL---------CLPLQPNLANVVVALALLGKLCAQVTACVATLYRIELFPTNVRPRCHGHRQNALGAVAMCGSVGSLLAPLVNRAALV 366          

Query:  705 IESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFI---FFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLV-------DI------------GILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKR--KIGFLLIGGVGSLLLFISIFFSKSIPLQS-VIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTL---IYFSFLWIVGVVVYFSLPETKDLPIPETLIDM 1613
            +E ++++ R   G      +T   +V    ++  RDWR   L   I + FY+F    +  PES RWL +    +  +  L+ ++ IN  + +  +    ++ L KE        + D   R    +F   +I  +    LV       D+               +    L V    +     ++    +    +R  + G L +  + S  L        +IP +S   R  L  L K A+S       +Y  E+FPT  R  G+ L    + ++  G +L   + +    LP L   +Y S   + G +VYF LPET + P+PET+ ++
Sbjct:    1 VEWIAMKDRTLYGMLSGVAYTTGQLVLVALAYYIRDWR--HLQHSISAAFYVFFLCSWCTPESARWLVMRGHYERALHGLKRVAVINGRKREAAQLTSPLQYLRKE-------LEEDTGPRRFYTMFNLLTIPALRRRTLVMSLVWCDDVFCWYAGFVVIVTRTCAHTFLLQVIYGAIDYPAKVVGLVVLSLLGRRATQAGSLAVASIASFCLL-------AIPAESGTARTCLAVLGKGALSCSFNCAYLYTGEIFPTVIRQSGLGL---CSTMARVGGMLAPLVIMAGESLPALPLSMYGSASLVAGSLVYF-LPETLNRPLPETIEEL 311          

Query:  456 LVCDNRYLGDVILMVWYAMFLLGPFVG-FMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLS-ASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWR-LSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESL-RFMSK----------INRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKI---GFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLK 1625
            L+CD  ++   +   +++   +G  +G  +SD FGR+  + LS  +   S +  + +   +     R  +G S AS +  S +++IE +  ++R   G     +++  Y +  +  +  RDWR L+    L+P+ F+L     PES RWL   NR DE ++ L R+ S+          +     D+ +DQI  E   K  +I    +    + R+++  F  F + L++    + +  L+ N+Y++  ++  + +P L   ++++    R+     ++L  G  SLL+ +++F  K+ P+ + +  ++G   K  I++   NI ++ +EL+PT  R+ GI    +S  L    A  I++L  +S  LP  I+     I G++  + LPET+ + +P+T+ +++ +K
Sbjct:    3 LICDRAHIAASLQSCFFSGMAVGSLLGGLISDAFGRRLCMFLSCGILVISGVAASFADCLSLLGLLRFCIGFSLASFMLSSYIYMIELIGPQYRTMGGQISHVFYSPGYCLTALIGYFVRDWRYLNMTCCLLPAFFFLTWKVFPESARWLIANNRLDEALQVLSRYGSRSGSDPVDLVALKEGIKDIRRDQIEREQHAKRTSILDLLRTRKLRKRTLILAFNWFVVALVHFGFYLYVTSLAGNVYVNFVIMNSIYIPHLFFCWFLMHRYGRRFPYSSYMLSAGAASLLI-LAVF--KAYPVGATVLAIIG---KTLITTEFSNIYLFTSELYPTILRNTGIGAGSMSARLGGILAPYISQLPGVSLTLPVTIFGVSAVIAGILSLW-LPETRYITLPQTIEEVETVK 402          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSKSKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNI---VILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWR-LSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLV----KEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRK---IGFLLIGGVGSLL-LFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEE 1640
            M  D++L  + +    +   + +L L    +  Q+  ++F    P++ C  NS +     K++         + C E  ++     +++++++ LVC+N Y  D++  +  +  LLG  + G ++D++GR+ +    +  LV+  F+S   + +P F  Y T R L G       +S  V   E V   +R F G     ++T+  ++ P+ ++L +DWR LS + +L  SVF LF  ++PES RWL +  R  E    L  ++  N +   V K  + V +      + G   + C       ++ + +F  F   L+Y  + ++   L+ ++Y++ FL  LME P+ L   + + +  R+     ++++ G+  +  +F+     +S P    +  V   + K  I++    I +Y  E+FPT  R+ G+ +  +S+ +    A  +  L      LP +I+    ++ G++    LPET   P+PET+ D KM K    +
Sbjct:    1 MEFDHVLKIVGEFGPHQRRLYVLLCLSIVPAAIQLLLLVFVAAQPHWIC-LNSSTNETCPKNK---------LQCTERQYT--SKYTSIITEWDLVCENAYKADLVQSLLMSGTLLGALMFGALADKYGRRRVWHTTLTGLVVFGFAS---SFAPTFKIYATLRFLTGFCIGGEILSAFVLATELVGPSYRGFAGIMAQCFFTLGLLILPMVAYLIQDWRTLSVVLSLPASVFILFFRYVPESARWLMIRGRVSEAENILLDIALKNGIA--VPKSLLQVNHPFFVGSRYGFFDLFCTR-KIVKQTFVLIFIWFVNTLVYYGLSLNTKHLAGDIYMNFFLCSLMEFPAYLTCLFFVNWAGRRKTLFNYMVLAGLACMACMFVQ---PESSPADRTLATVFAMIGKFGITASFALIYIYSAEIFPTVVRNVGLGVCSMSSRIGGICAPFVVFLGTYMRPLPMVIFGMCAFMAGLLS-LMLPETHKRPLPETMDD-KMFKANDSD 480          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSKSKFIVSKDQCSILMNGT------------TMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKE-----GNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLF---ISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLI 1478
            M +D ILS I     F+    FIL L  F +  Q   I+F    P +KC          ++D  +  +NGT            +MN  +W+F+     +++VS++ L+C    +  +   + +  ++ G F+ G +SD FGR  ++  S+ +   +S+  + + +   YL  R ++G     VYI + V   E V    R   G+  W ++T++ +     ++   DWR   +   +P++   F + +PES RW  V NR  E  ++L  ++K+N    ++  D +   N V+E     G I    K      ++++  F   +  ++Y  + +  G+L  ++YL+  L  L+ELP  L S + +          L+G V  L L    I++FFS+      VI+I+   L K  IS     I V   EL PT  R+ G+  + + + L  S A  I
Sbjct:    1 MDIDKILSSIGGFGFFQKRNSFILGLVIFIATFQTVLIVFVGMEPPWKC----------AQDSTTCTLNGTFSSGDENYDSRCSMNRSDWEFT--SGFTSIVSEWDLICGKAAMASLAQSILFIGWIPGAFIIGKLSDMFGRTRMLFPSIAVVAVASLSCSFAQHLWLYLVLRAIIGFFEGGVYIVLYVLSTEFVGPAHRSLAGTLNWVFFTLSLITLDGLAYGLHDWRHLSIAVSVPALPLFFFWLVPESCRWQLVNNRCKEARQTLEHIAKLNGK--NLPSDVMPAINNVEEEKSFRGGILDLFKPRQQLKQTLILWFSWLTNAMVYYGVTLSAGVLGGSLYLNFLLASLVELPGNLFSIWFMN---------LLGLVCMLCLASANITLFFSQGPGHYQVIKIISAVLGKFCISISFCTIYVTSTELLPTVIRNIGMGSMAVFDQLGASLAPFI 434          

Query:  180 LDNILSDINK--PLTFKIVAFFI-LSLP-TFQSCSQIQNILFALFIPNFKCRFNSKSKFIVSKDQCSILMNGTT----------MNCKEWDFS-----LLPIGSTLVSDFGLVCDNR---YLGDVILMVWYAMFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGL-SASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVF-YLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVI--RIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETL--IDMKMLKCGKE 1637
            +D +L  I +  P   +I+A F+ + +P T+Q+   +    F  + P + C  NS +  + +     I    T           +N  +W F+       P+  T+V+ F LVCDN    +L + +L   +A+  +   +G ++D++GR++++  S       +  ++ +      +  R   G     ++    V   E V    R    +  WFY+T+A MV  + ++  +DW+L  + + +P VF ++F  F+PES RWL V+ RKD+  E L  ++K+N+   ++ K+ + V  +                  +++  +      L+Y ++ +  G    ++YL+  L  ++E P+ +L         RK   +    VG++   +  F          I  R+  G L K+ I++   ++ V+  ELFPT  R+ G+ LL + + +  + A  + +L+ I+  LP  +     ++  +  +F LPET+  P  E +   D + L+ GK 
Sbjct:    5 VDQVLEQIGQFGPFQIRILAMFLFIFIPLTYQTLLMV----FVAYEPPWMCTTNSSACLLSNSTGREIYSTSTQPIELYHRRCKLNRTDWKFADPELYEGPV-HTIVTQFDLVCDNSFHAWLANSMLFFGWALGAI--ILGMIADKYGRRSVLFPSAACVIAITFSMSFAQASWVVIALRFFSGFFLGGSILTMFVLAAELVGPAKRALSSTMVWFYFTLALMVLGLQAYFIKDWKLLCIISTVPFVFIFIFWKFIPESVRWLLVVGRKDQAREILEQVAKVNKK--EMPKEDLRVPVVKHNRGFLELFGTPRLALLTLLQCYAWLVNGLVYYAVSMSAGDFGGSIYLNFVLTSIVEFPANILVIDNCNRFGRKHTVVWYTVVGAISCLVVSFIPSGTDNIGYIAGRVAAGTLGKLCITTSFNSLYVFSAELFPTMIRNSGMGLLSVISRVGAALAPFVVQLTRINAILPFALMSGLTFLAALACWF-LPETRGKPTLEVMGDDDPQHLEQGKH 508          

Query:  171 QMFLDNILSDINK--PLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSKSKFIVSKDQCSILMNGTT----------MNCKEWDFS-----LLPIGSTLVSDFGLVCDNR---YLGDVILMVWYAMFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISI-VWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVF-YLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLS-VFXXXXXXXXXXXXSYYVLRYIKRK--IGFLLIGGVGSLLLFISIFFSKSIPLQSVI-RIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLID 1610
             + +D +L  I +  P   +I+A F+     F    Q   ++F  + P + C  NS +  + +     I    T           +N  +W F+       P+  T+V++F LVCD+    ++ + +L   +A+  +  F+G ++D++GR +++  S +L    S+ +A        L  R  +G      ++S+ V   E V    R   G+  W Y+T A MV  + +F  RDW    + ++ P VF  LF  F+PES RWL V   K +    L  ++++N+    + +++++   +     I            +++  +  F   ++Y  + +  G    ++YL+ V    +    ++LL +   R+ +++  + + LIG +  +   +S   + +  L  +I R+  G L K+ I++    + V+  ELFPT  R+ G+ LL + + +  + A  + +L+ I+  LP  +     ++  +  +F LPET+  P  E + D
Sbjct:    2 ALVVDQVLERIGQFGPFQKRILAMFMFIF--FPLTYQTLIMVFVAYEPPWMCSTNSSACLLSNSTGREIYSTSTQPIELYHRRCKLNRTDWKFADPELYEGPV-HTIVTEFDLVCDHSFTAWMANSMLFFGWAIGAI--FLGIIADKYGRCSVLFPSAILVMGLSLAMAFVKKAWLVLVLRFFIGFFEGGGFLSMFVLATELVGPAKRALAGTLVWIYFTAALMVLALKAFFIRDWSTLCIISIAPFVFIVLFWKFVPESVRWLLVTGSKGKARRILENVARVNKK--SMPEEELFAPQVEHNRGIIELFSTKRLAVLTLLQCYAWFVNGMVYYGVSMSAGDFGGSIYLNFVLTSLVEFPANVLLIHNCNRFGRKRTVVAYTLIGAIACIT--VSFIPAGTNNLGFIIGRVTGGMLGKLCITTSFNGLYVFSAELFPTMVRNSGMGLLSVISRVGAALAPFVVQLTRINAILPFALMGGLTFLAALACWF-LPETRGKPTLEVIGD 497          

Query:  387 TMNCKE-WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPF-VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYIS-IVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYL-FIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRF----------DVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAV---LINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEE 1640
            T  CKE W++       + V++F LVC + ++ D+        FL+G   +G+++DRFGRK   ++S ++   + IL+A+SPN+ + L FR L G      +++  V + E V +EFR  +G  Y  +++V  ++ P+ +F   DWR  QL    P + +L + +F+PESPRWL   N+K ++++    ++K NR             D + +     +L++  N+         +  +++  +  F+  ++Y  +++ +GIL  N+Y+   + GL+E P+  L  + +  I R++ F     V      I+ F    + L   ++ V+ C+ ++ I+   + ++    EL+PT  R+ G++  + S      G V   L+ RL+VI   LP LI F FL  +   +   LPET+ +P+P+++ D++  +  K+E
Sbjct:  114 TTACKEGWEYDY-EGRQSFVTEFDLVCSHGWMADMFQATLNVGFLVGSIAIGYLADRFGRKMSFLMSTLVNAVAGILVAVSPNYTSLLVFRSLSGFGVKGGWMAGYVLITEIVGVEFRRTVGVLYQMFFSVGLLILPLLAFFITDWRWLQLAITAPYILFLSYYWFIPESPRWLLSQNKKSQVVKITESIAKENRRVLSKNIETLTDDDADSNSASFMDLIRTPNM---------RKHTLILSYNWFTSAVVYQGLIMRLGILGGNVYVDFLISGLVEFPAAFLILFTIERIGRRLPFASANMVAGASCLITAFLPDDLFL---LKTVVACIGRLGITMAFEMVVFVNTELYPTFVRNLGVS--VCSTLCDVGGIVAPFLLYRLAVIWLELP-LIIFGFLAFLAGGLVLLLPETRGVPLPDSIQDVEFPERVKQE 532          

Query:  240 ILSLPTFQSCSQIQNILFALFIPNFKCRFNSKSKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYI-SIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIF-FMPESPRWLCVMNRKDEMMESLRFMSKINR-------LRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRK---IGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSS 1715
            ++S+P  Q  S     +FA   P +   +N  +     K  C+   NG       W +      STL S + LVCD + +      +++   +LG  + G++SDRFGRK  +++S +  T      A S NF  ++  R L G+  S + I SIV  +E V I+ R ++G      W+ + +V P  ++   DWR        P +  +  + ++PES RWL    + D     L   + +N        L+ +V    I VE+  ++ +     K    +  +++     F +   Y  + +++     N+YL+ F+ G+ E+P+     + L  I R+   +G LL+ G   L +F +IF  +    Q   R  +G L K+   +    + +Y  EL+PT  R  G+        +  S + L+  L      LP  I+ +  +I G+   F LPET+++ +PET+ D++              Q + +    ++  SDEKS+
Sbjct:   70 VVSIPAQQDGSSHSCQMFAE--PQYHLVWNGTNSTDPLKIPCT---NG-------WWYDNTTFKSTLASQWDLVCDKKSMNRATATIFFMGVMLGAAIFGYLSDRFGRKRTLLVSYIATTTFGFASAFSYNFPMFVAMRFLTGVGISGISIVSIVLCVEWVDIKHRTYVGVLMSLDWSFSTVVLPALAYFVNDWRSLTATVTAPLLAAMITWRWLPESARWLISTGKVDRAHFYLHQCATVNHREDFMADLKPEVLSKVILVEDENRKYSYVDLVKTPRMRRLALLTGIVWFGVACTYYGISLNVTGFGVNIYLTQFIYGVTEVPAKAFIVFFLNKIGRRLTQVGTLLLTG---LCIFCNIFIPQD---QVAARTTVGALGKMLAEAAFTTVFLYTTELYPTVMRQNGLGYSSFMARIGVSVSPLMMILEETWIHLPNTIFSAVAFIAGLSASF-LPETRNIRLPETIEDVE--------------QKRRR----SIPTSDEKSA 537          

Query:  405 WDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYI-SIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPS-VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINR--LRFDVEK-DQIYVEN----LVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKR--KIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLP--TLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSEN 1721
            W++S     ST V+++ LVC+N  + ++   V+    L+G  V G ++D++GR+ I+++SL ++       A +PNF  Y   R ++G S S V + + V   E   ++ R   G    +++   Y++    ++L RDWR  QL    P  +F ++I+ +P+S RWL   NR +E +E +   +++N   +  D+E   Q+Y  +    L K+ +     +    +  S++  +  F   L+Y  + ++I     N+YL+  + GL+E+P+  ++ + L   ++  ++ FL +GG   LL   +IF    +    +++ VL  + K  I++    I VY  E+FPT  R  GI    I +  + +G VL   + ++    P   ++      ++G  +   LPET + P+P+T+ D++ +     ++ V     K   F+  +  + E+S+  
Sbjct:  101 WEYSTETFQSTTVTEWDLVCENASMNNLGSSVYMFGLLVGALVFGNLADKYGRRIIILISLAIQAVFGTAAAFAPNFYVYTALRFMVGTSISGVIMNAFVLGTEWTGLKQRMLAGIITDYFFGFGYILLAGLAYLIRDWRKLQLAISAPGFLFIIYIWVLPKSARWLMANNRVEEALEVIEKAAQMNGKPISKDIEMCQQVYKADQNSVLKKKHSFIDLVRTPTMRKNSLIVFYLWFVNVLVYYGLSLNISDFGMNIYLTQMIFGLVEMPARTITLFTLNRSRKISQLAFLAVGGSACLL---TIFIPSRL---FIVKTVLAMIGKFGITASLSIIYVYSAEVFPTVIRQNGIG---IGSMCARTGGVLAPMMYLLRNISPHAPMVLSGLCPLLGAGLTLLLPETANKPLPDTIEDVEGVIASDGDDAV-----KTVLFDLPLPKTAEESTRT 539          

Query:  399 KEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFV-GFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYI-SIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLF-IFFMPESPRWLCVMNRKDEMMESLRFMSKINR--LRFDVEKDQIYVENLVKEGNICVA-CKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKR--KIGFLLIGGVGSLLLFISIFFSKSIPLQSV-IRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVL---INRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMK 1616
            + W +S     S+ V+++ LVC+   L  +   V+ +  L+G  V G M+DR+GR+ +++LS+ L+T   + +A +PNF  Y+  R  +G + S V I + V   E    + R   G    + + + YM+    ++L RDWR  QL    P    +F I  +P+S RWL   +R +E +  LR  + +N   L   V+ ++  +    K  +  V   +    + R+++  +  F   L+Y  + + +  L +N+Y++ F+ GL+E+P+  L    L + +R    GFL +GG+  LL+        ++P     +   L  + K  I++    I VY  E+FPT  R  GI    +S+  +  G VL   IN L   S   P LI F    ++G ++  +LPET D P+P+TL D +
Sbjct:   90 RGWVYSSEVFESSTVTEWDLVCNRAGLNSLGSSVYMSGLLVGSVVFGAMADRYGRRFVLLLSIALQTVFGVAVAFAPNFPVYVLLRFAVGTTISGVIINAFVLGTEWTCTKRRMLAGIITDYTFGLGYMLLAGVAYLIRDWRKLQLAISAPGFLLIFYIRVLPQSARWLLANDRTEEAIALLRKAALVNGRVLPPAVQVEKWEILGGSKRSHSAVDLVRTPQMRKRTVILFYIWFVNVLVYYGLSLGVSRLGTNLYMTQFVFGLIEIPARSLVLIFLPFSRRLSLSGFLAVGGLACLLML-------TVPEDHPNVLTGLAMVGKFGITASFAIIYVYTAEIFPTVVRQTGIG---VSSMFARMGGVLAPIINMLDSHSPATP-LIIFGTSPLLGALLALALPETADRPLPDTLEDAE 496          

Query:  375 MNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYA-----MFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYI-SIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIP-SVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRF-DVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGF---LLIGGVGSLLLFISIFFSKSIPLQSVIRI-VLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSKL 1742
            +N TT+    W +S +   ST+V+DF LVCD  +L +V   V+ A       LLGPF    ++ FGRK    + + L    S+   L PN   YL  + ++G+      + S++ + E +    R +       +  +   V     +  R+WR++Q     P +V  ++I+F+PES RWL    R DE    +  ++ IN+    D   ++I ++    +G I V  +    +   +  +   FS+NL Y  +  ++G    +++L+  + GL ELP+ +L  ++L ++ RK+     LLIGG     L  SI    ++P  + I +  L    +   +       +YV ELFPT+ R     L  I++      + L+N L+V  + +P ++Y S   + G + Y  LPET+   +P++  +                  + K  N T  N  E +   LN+ +KL
Sbjct:  101 LNDTTVCTNGWVYSNMKYESTIVTDFDLVCDQAFLKEVAQAVFMAGILAGCLLLGPF----AESFGRKRATQIPVFLMLIFSVTTGLCPNLYLYLLSQFIVGIGYGGYRLNSVILVTEWIGPSQRSWGACATQLFGALGQSVLAGLIYYIRNWRMAQFIIATPFTVVSVYIWFIPESARWLLGRGRIDEAKLLITKVAAINKRTISDSILEKIVMKETETKGGIIVLFQSPVLRKYFLTIIMAWFSLNLTYFCLSFNVGNFGLDIFLTQAMFGLTELPAHILCIWLLEFVGRKVSIMSTLLIGG----FLCFSIL---AVPQDNAIAVTTLAIAGRFFTNWAGSVCSLYVQELFPTSFRQTASGLGSIASRAGGLLSPLLNMLAVYHWSIPIVVYSSLTVVSGALSYL-LPETRKRELPDSTDEA-----------------EGKLKNTTSRNQPESNKPALNKSTKL 539          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSKSKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSKLITGKNK 1760
            MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKC+FNSKSKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGP VGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSA                                      ++S    D  +  +   +  VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSI ALFCAFSINLIYSSMLVDIGILSSNMYLSVFLLGLMELPSLLLSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFN+TVDNSDEKSSENLNEKSKLITGKNK
Sbjct:    1 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCKFNSKSKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPLVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSA-------------------------------------ILSSGRLLDRSIGSIGQSLTCVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSITALFCAFSINLIYSSMLVDIGILSSNMYLSVFLLGLMELPSLLLSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNHTVDNSDEKSSENLNEKSKLITGKNK 492          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSK-SKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSKLITGKN 1757
            M L++IL D NK  TFK +AFFILSLP+FQ  SQ+QNIL + + P + C +NS  SK  +S DQC+++++G+T+ C +W+FS  P+G T++SDF LVC+ + LGD+IL+VWY+  + GP +G+ SD+FGRK + I +L LET S+  ++ +P+  + +  R+L+G+SA+  Y   VWL+E V  EFR F GSF W Y  +AYMVFP+T++  +DWR++QL +LIP++ Y  I   PESPRWLCV NRK E+++SL  +++IN++  ++  +QI+V     E N   A KD  F  R  ++    FSINLIY+++ V++ ILS+NMY+S+FLLGLME P +L SY  LR+ +RK  F+LIGG+GS+ + IS+FFS++I  Q VIRI+ GC++KIA+++CNQ+ MVYV+EL PT+HRS G   + ++N  SF+ A+ IN+LS + +FLP +IYF  +++   ++Y  LPETK+LPIPETL+D KMLK  KE+EF+ YM  K +    +  + D   S    E+S LI  K+
Sbjct:    1 MILEDILKDYNKRNTFKFLAFFILSLPSFQFSSQMQNILISTYTPKYTCLYNSSFSKISISADQCNMIIDGSTIVCNKWNFSYEPVGRTMMSDFSLVCNYKNLGDIILIVWYSTSITGPIMGWFSDKFGRKKVAIFNLCLETISTFFVSFTPDVTSNIICRLLIGISANGFYTCYVWLMEMVDNEFREFSGSFIWTYGCLAYMVFPLTAYFTKDWRITQLISLIPNILYFLILLFPESPRWLCVTNRKSELIKSLNKIAEINKIDTNINYEQIFVPKTKDEHNTWKALKDKTFSLRMTLSFLLVFSINLIYAAIAVNLQILSNNMYISMFLLGLMEFPGILFSYVSLRFFRRKTSFILIGGIGSIFILISVFFSRNILWQGVIRIIFGCIAKIAVTTCNQSTMVYVSELCPTSHRSLGFASIQLANLCSFTAAIYINKLSTVLFFLPMVIYFILMFLTSCIIYLYLPETKNLPIPETLLDQKMLKVNKEKEFLDYMNKKREMEVESDLDLDLLKSNESTEESHLINRKH 529          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSK-SKFIVSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSKLITGK 1754
            M L++IL D NK  TFK +AFFILSLP+FQ  SQ+QNIL + + P + C +NS  SK  +S DQC+++++G+T+ C +W+F   P+G T++SDF LVCD + LGD+IL+VWY+  + GP +G+ SD+FGRK + I +L LET S+  ++ +P+  + +  R+L+G+SA+  Y   VWL+E V  EFR F GSF W Y  +AYMVFP+T++  +DWR++QL +LIP++ Y  I   PESPRWLCV NRK E+++SL  +++IN++  ++  +QI+V     E N   A KD  F  R  ++    FSINLIY+++ V++ ILS+NMY+S+FLLGLME P +L SY  LR+ +RK  F+LIGG+GS+ + IS+FFS++I  Q VIRI+ GC++KIA+++CNQ+ MVYV+EL PT+HRS G   + ++N  SF+ A+ IN+LS + +FLP +IYF  +++   ++Y  LPETK+LPIPETL+D KMLK  KE+EF+ YM  K +    +  + D   S    E+S LI  K
Sbjct:    1 MILEDILKDYNKRNTFKFLAFFILSLPSFQFSSQMQNILISTYTPKYTCLYNSSFSKISISADQCNMIIDGSTIVCNKWNFLYEPVGRTMMSDFSLVCDYKNLGDIILIVWYSTSITGPIMGWFSDKFGRKKVAIFNLCLETISTFFVSFTPDVTSNIICRLLIGISANGFYTCYVWLMEMVDNEFREFSGSFIWTYGCLAYMVFPLTAYFTKDWRITQLISLIPNILYFLILLFPESPRWLCVTNRKSELIKSLNKIAEINKIDTNINYEQIFVPKTKDEHNTWKALKDKTFSLRMTLSFLLVFSINLIYAAIAVNLQILSNNMYISMFLLGLMEFPGILFSYVSLRFFRRKTSFILIGGIGSIFILISVFFSRNILWQGVIRIIFGCIAKIAVTTCNQSTMVYVSELCPTSHRSLGFASIQLANLCSFTAAIYINKLSTVLFFLPMVIYFILMFLTSCIIYLYLPETKNLPIPETLLDQKMLKVNKEKEFLDYMNKKREMEVESDLDLDLLKSNESTEESHLINRK 528          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCRFNSKSKFI-VSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMALFCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSKLITGK 1754
            M L+N++S  NK  TFK++AF ILSLP FQ  SQ QN+L ++  PNF C++N  S  I +SKDQC++ +NG+ + C+ W FS  P G T++SD+ LVCD +Y+GD+++++WY+  L+ P  G+++D++GRK I I+ L +ET ++ +LA +PN  +++ FR+ +G S SA +I  VWL+E V+ +FR   GSF+W Y +VA  VFP+T ++ R+WRL+QL +L PS+ Y+ I F+PESPRWLCV N+K ++MESL+ ++ IN++   +  ++I +E   KE N   A KD +F   +  +LF  FSI+++ S++L+D+ +LSSN+Y+S+F+LGLME P  LLSY  + + KRK    +    GS+ +F+S+  SK    QS+ R++ G + K+ + + +Q ++VY  ELFPTTHRS    +L I   ++ + AV IN+L+    F+P LIYF    I   +++  +PETK LPIPET+ D ++L   +E+E++ YM N+     + V NSD + S+  +E S+LI  K
Sbjct:    1 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIRTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGETIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLYSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPEEIKIEKTTKEWNKWNAFKDMNFLFLASTSLFAVFSISILISAILIDLNLLSSNIYISMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVMTSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNR-----SDVVNSDREDSDASSEMSQLINRK 523          

Query:  174 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCR---FNSKSKFIVSKDQCSILM---NGT--TMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPFVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSIMAL------FCAFSINLIYSSMLVDIGILSSNMYLSVFXXXXXXXXXXXXSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLL--ISNFLSFSGAVLINRLSVISYFLPTLIYFS------FLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFN 1682
            M  +  +S+I     F ++A   LS+    S   I +I+F    P++KC    FN +++   +  +C  +    NGT  T+ C+ W ++   + +T+ ++F LVC+ +    ++  +++    +G F+    D+ GR  ++ L+++ E   +I L  + N    +  R L GL    +Y  + +L E VSI+ R    + YW  + + YM+ P  ++  +DWRLS+     P +FYL  F +PESPRWL +  +  + + +L  ++K N   F   K    +    K GNI      TD     IM L      F   +I++ Y  + ++   LSSN++L+VF+ GL+E  +  +++ +   + R++  L+   + S+ L ++ F+S +  + S++   LG + K A+++      +Y+NE+FPT  R+  I ++L   S F  F+ ++     + I  F+P   YFS         I G+++YF LPETK  P+P+TL +   L+ G E  +   +    + +N
Sbjct:    1 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFN-QTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNFPLLFYLTYFLLPESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNI------TDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFNNIIVSIVISTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSI-----NGIDEFIP---YFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCNMILKHDELYN 510