Amiloride-sensitive sodium channel subunit gamma
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30004942 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Human
Match: ASIC2 (acid sensing ion channel subunit 2 [Source:HGNC Symbol;Acc:HGNC:99]) HSP 1 Score: 119.783 bits (299), Expect = 4.215e-28 Identity = 122/477 (25.58%), Postives = 199/477 (41.72%), Query Frame = 1
Query: 70 EIKRKKLEDVLGEEATSMLNNTSCL-AIGNIFIRNHPLL--KTLWCIAFILCTILTIRQLYNLSSSYFSYP-LNTVIRLQSEPIDFPSITFCNLNPLRYSQLNLSKP-SLQEFFKQLENRQFVKD---NDNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCL---LQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAI 1434
++K E L + + NTS L I +IF+ PL + LW +AF+ L + + S YFSY + V + ++ + FP++T CNLN R+S+L + E L+ + D D ++ L + FK + S F +G+ LKD +L C F G++C + F + KYG C+ FN K GL I +Q DEYL F +++H Q EP ++ G + PGF+T + ++ G C+ + VY+ AC C I C C ++ + C + +C L + ++ + N C C CN T Y + S + P+ + K + FN + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + I
Sbjct: 2 DLKESPSEGSLQPSSIQIFANTSTLHGIRHIFVYG-PLTIRRVLWAVAFVGSLGLLLVESSERVSYYFSYQHVTKVDEVVAQSLVFPAVTLCNLNGFRFSRLTTNDLYHAGELLALLDVNLQIPDPHLADPSVLEALRQKANFKHYKPKQFSMLEFLHRVGHDLKDMMLYCKFKGQECGHQD--FTTVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQE---LGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSE-MGLDFFPVYSITACRIDCETRYIVENCNC-----RMVHMPGDAPFCTPEQHKECAEPALGLLAEKDS--NYCLCRTPCNLTRYNKELSMVKIPSKTSAKY-------LEKKFN---KSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYI 454
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Human
Match: ASIC2 (acid sensing ion channel subunit 2 [Source:HGNC Symbol;Acc:HGNC:99]) HSP 1 Score: 111.694 bits (278), Expect = 2.328e-25 Identity = 116/462 (25.11%), Postives = 179/462 (38.74%), Query Frame = 1
Query: 145 AIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNT-VIRLQSEPIDFPSITFCNLNPLRYSQLN------------------LSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQEPGALEMPEI--YGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDY-LNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAI 1434
A G F R + LW +AF L + N + S+P +T V R S + FP++T CN NPLR+ +L+ ++P + E + E R+ + +L D LF E F +G+QL+D +L C + GE C F + KYG C+ FN K GL I +Q DEYL F +++H Q E P I G + PGF+T + ++ G C+ + VY+ AC C I C C ++ + C + +C + N C C CN T Y + S + P+ + K + FN + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + I
Sbjct: 78 AAGGSFQR-----RALWVLAFCTSFGLLLSWSSNRLLYWLSFPSHTRVHREWSRQLPFPAVTVCNNNPLRFPRLSKGDLYYAGHWLGLLLPNRTARPLVSELLRGDEPRR-------QWFRKLADFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSCKYRGELCGPHN--FSSVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQS----EPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSE-MGLDFFPVYSITACRIDCETRYIVENCNC-----RMVHMPGDAPFCTPEQHKECAEPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPSKT-------SAKYLEKKFN---KSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYI 505
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Human
Match: ASIC1 (acid sensing ion channel subunit 1 [Source:HGNC Symbol;Acc:HGNC:100]) HSP 1 Score: 109.768 bits (273), Expect = 8.573e-25 Identity = 127/502 (25.30%), Postives = 205/502 (40.84%), Query Frame = 1
Query: 79 RKKLEDVLGEEATSM---LNNTSCLAIGNIFIRNH-PLLKTLWCIAF-----ILCTILTIRQLYNLSSSYFSYPLNTVI-RLQSEPIDFPSITFCNLNPLRYSQLNLSKPSL---QEFFKQLENRQFVKDN---DNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNS------VYTKQACLYVCLQNVIFSKCQCY------DAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE-AISLITTYLCSK 1464
+ + E+V G + S+ ++++ + +IF L + LW + F +L + T R Y YF Y T + + + + FP++T CNLN R+SQ+ SK L E L NR + D D + + L D+ F+ + F G+ ++D +L C F GE C E F ++ +YG C+TFN K GL I +Q DEYL F +++H Q EP ++ G + PGF+T + ++ G CK T +S Y+ AC C + C C DA Y + C D + L++ ++ C C CN T Y + S + P+ + K + FN + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + A +I LC +
Sbjct: 4 KAEEEEVGGVQPVSIQAFASSSTLHGLAHIFSYERLSLKRALWALCFLGSLAVLLCVCTERVQY-----YFHYHHVTKLDEVAASQLTFPAVTLCNLNEFRFSQV--SKNDLYHAGELLALLNNRYEIPDTQMADEKQLEILQDKANFRSFKPKPFNMREFYDRAGHDIRDMLLSCHFRGEVCSAED--FKVVFTRYGKCYTFNSGRDGRPRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQ---LGFGVAPGFQTFVACQEQRLIYLPPPWGTCKA-----VTMDSDLDFFDSYSITACRIDCETRYLVENCNCRMVHMPGDAP---YCTPEQYKEC-ADPALDFLVEKDQEY------CVCEMPCNLTRYGKELSMVKIPSKASAKY-------LAKKFN---KSEQYIGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHKLCRR 468
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Human
Match: SCNN1B (sodium channel epithelial 1 beta subunit [Source:HGNC Symbol;Acc:HGNC:10600]) HSP 1 Score: 106.301 bits (264), Expect = 1.966e-23 Identity = 109/491 (22.20%), Postives = 188/491 (38.29%), Query Frame = 1
Query: 175 PLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENR---------------------------------------QFVKDNDNEMVSRLYDEN------------LFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQ---IEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVD------IKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQL-----YLKN---INHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDI---KDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAI 1434
P K +W + +L L Q +Y S+ ++ + + + +DFP++T CN +P +YS++ L E + + R DN N + S E L + + EM Y + IL C F E C +F+P YGNC+ FN + ++ GL + + ++Y+ + G+RL E + G+ G ETSIG++ K++R + + G+ F YN+ Y+ QACL C Q+ + C C ++ L Y N + C +D ++ + T + C +CN T Y + S A+WP+ + E F+ + +D N ++ R+ + + IY ++ +Y+ I + A LS++GG ++G SVL EF E I
Sbjct: 46 PKKKAMWFLLTLLFAALVCWQWGIFIRTYLSWEVSVSLSVGFKTMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYP----HYGNCYIFN-WGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETC-------IGMCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQERDQSTNITLS-------RKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEII 517
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Human
Match: ASIC1 (acid sensing ion channel subunit 1 [Source:HGNC Symbol;Acc:HGNC:100]) HSP 1 Score: 105.145 bits (261), Expect = 3.368e-23 Identity = 118/488 (24.18%), Postives = 195/488 (39.96%), Query Frame = 1
Query: 73 IKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNHPLLK-TLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVI-RLQSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQEPGALEMPEI--YGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNS------VYTKQACLYVCLQNVIFSKCQC---YDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE-AISLITTYLCSK 1464
++++ E + + N+ + +IF+ P + LW +AF+L + Q+ + + Y SYP T++ + + + FP++T CN N +R SQL S P L L + +D + F N RF ++L+D +L CS+ G C F ++ +YG C+TFN K GL I +Q DEYL F +++H Q+ E P I G + PGF+T + ++ G CK T +S Y+ AC C + C C + Y + C D + L++ ++ C C CN T Y + S + P+ + K FN + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + A +I LC +
Sbjct: 51 VRKEASEGHSPMDLVAFANSCTLHGTNHIFVEGGPGPRQVLWAVAFVLALGAFLCQVGDRVAYYLSYPHVTLLNEVATTELAFPAVTLCNTNAVRLSQL--SYPDLLYLAPML---GLDESDDPGVPLAPPGPEAFSGEPFN---LHRFYNRSCHRLEDMLLYCSYQGGPCGPHN--FSVVFTRYGKCYTFNSGRDGRPRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQD----EPPFIDQLGFGVAPGFQTFVACQEQRLIYLPPPWGTCKA-----VTMDSDLDFFDSYSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQYKEC-ADPALDFLVEKDQEY------CVCEMPCNLTRYGKELSMVKIPSKASAKYLAK-------KFN---KSEQYIGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHKLCRR 502
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Match: del-4 (DEgenerin Like [Source:UniProtKB/TrEMBL;Acc:P91835]) HSP 1 Score: 154.451 bits (389), Expect = 2.132e-40 Identity = 118/463 (25.49%), Postives = 203/463 (43.84%), Query Frame = 1
Query: 133 TSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQL----ENRQF-----VKDNDNEMVSR---LYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKT-YNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICD----TDSKIQCLLQVTSDFN---DYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCS 1461
TS + +I + N L+ W + ++ L I Q L ++Y S+ +NT LQ FP++T C+LNP + S+ P + + QF + + + S+ +Y E L +K N+ + ++ Y D ++ C++ + C I F + YGNC FN Y+ S + GL + D YL + ++G+ + + P+++G PPG +S+G+ + R G+C + T Y YT +AC C+Q I + C CY + ++ CD T S + C+ + S + D L C+C C +Y + S A+WP+ SY N P + + N + IY E ++Q + + AY + NF+SD+GG + L+LG S+++ E+L I L+ Y C+
Sbjct: 19 TSTHGVPHIGMANARWLRAFWILVVVVSIALFIWQFITLLTNYLSFSVNTETTLQFAERTFPTVTICHLNPWKLSETKSVDPDMSALIDAYNSDSSSAQFGLPASLTADRQQQASKWTLMYSERLNEKQY-NDAA----DIAYSYDDMVVSCTYNAKTCNITD-FNDFYNPSYGNCLQFNTDGMYSSS----RAGPLYGLRMVMRTDQDTYLP-WTEASGVIIDIHMQDEIPYPDVFGYFAPPGTASSLGVSYVQTTRLSKPYGSCTTKTKLKTTHYTGTYTVEACFRSCMQEKIIASCGCYYPAYSHASNTTQYVSCDNGVQTLSNLNCVDLINSADSTEFDVLTDCDCPQPCEIDSYGVTVSTAQWPSDSYVPTECNPGGPSGPWDASGESCLDWYKANTILIEIYYERMNFQVLTESPAYTFVNFISDVGGQVGLFLGMSIISAIEYLVLIFLVFFYCCT 470
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Match: unc-8 (Degenerin unc-8 [Source:UniProtKB/Swiss-Prot;Acc:Q21974]) HSP 1 Score: 142.51 bits (358), Expect = 1.504e-35 Identity = 99/320 (30.94%), Postives = 156/320 (48.75%), Query Frame = 1
Query: 502 KTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPST---GIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKT---YNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKI--QCLLQVTSDFNDYLNV---CNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
+TR + Y L +F+L+CSF + C +E+ F + +YGNC+TFN +N S + K SR+ ++ L N + ++P+T G+RL E P+ +G + P GF +S G+ ++ R GNC + FR YN Y+ + C C Q + C C D F L + H C+ SKI QCL +TSD Y ++ C C C+ + S + WP+ ++ + D + FN T + RQN + + IY E +++ + + Y N SD GG + L++GFSV+T EF E
Sbjct: 367 ETRRNLSYTLNEFVLRCSFNSKDCSMERDFKLHVDPEYGNCYTFN----FNDSVEL-KNSRAGPMYGLRLLLN-VHQSDYMPTTEAAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKTKELHRLSAPWGNCSDT--FRPVPYIYNEHYSPEGCHRNCFQLKVLEICGCGDPRFPLPSEEHRH--CNAKSKIDRQCLSNLTSDSGGYHHLHEQCECRQPCHEKVFETAYSASAWPSQNF--KIGTDCPAVSDIFNDTEACTEYYRQNTAYIEIYYEQLNFESLKETAGYTLVNLFSDFGGNIGLWIGFSVITFAEFAE 674
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Match: unc-8 (Degenerin unc-8 [Source:UniProtKB/Swiss-Prot;Acc:Q21974]) HSP 1 Score: 142.51 bits (358), Expect = 1.720e-35 Identity = 99/320 (30.94%), Postives = 156/320 (48.75%), Query Frame = 1
Query: 502 KTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPST---GIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKT---YNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKI--QCLLQVTSDFNDYLNV---CNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
+TR + Y L +F+L+CSF + C +E+ F + +YGNC+TFN +N S + K SR+ ++ L N + ++P+T G+RL E P+ +G + P GF +S G+ ++ R GNC + FR YN Y+ + C C Q + C C D F L + H C+ SKI QCL +TSD Y ++ C C C+ + S + WP+ ++ + D + FN T + RQN + + IY E +++ + + Y N SD GG + L++GFSV+T EF E
Sbjct: 406 ETRRNLSYTLNEFVLRCSFNSKDCSMERDFKLHVDPEYGNCYTFN----FNDSVEL-KNSRAGPMYGLRLLLN-VHQSDYMPTTEAAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKTKELHRLSAPWGNCSDT--FRPVPYIYNEHYSPEGCHRNCFQLKVLEICGCGDPRFPLPSEEHRH--CNAKSKIDRQCLSNLTSDSGGYHHLHEQCECRQPCHEKVFETAYSASAWPSQNF--KIGTDCPAVSDIFNDTEACTEYYRQNTAYIEIYYEQLNFESLKETAGYTLVNLFSDFGGNIGLWIGFSVITFAEFAE 713
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Match: unc-8 (Degenerin unc-8 [Source:UniProtKB/Swiss-Prot;Acc:Q21974]) HSP 1 Score: 142.124 bits (357), Expect = 1.756e-35 Identity = 99/320 (30.94%), Postives = 156/320 (48.75%), Query Frame = 1
Query: 502 KTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPST---GIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKT---YNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKI--QCLLQVTSDFNDYLNV---CNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
+TR + Y L +F+L+CSF + C +E+ F + +YGNC+TFN +N S + K SR+ ++ L N + ++P+T G+RL E P+ +G + P GF +S G+ ++ R GNC + FR YN Y+ + C C Q + C C D F L + H C+ SKI QCL +TSD Y ++ C C C+ + S + WP+ ++ + D + FN T + RQN + + IY E +++ + + Y N SD GG + L++GFSV+T EF E
Sbjct: 407 ETRRNLSYTLNEFVLRCSFNSKDCSMERDFKLHVDPEYGNCYTFN----FNDSVEL-KNSRAGPMYGLRLLLN-VHQSDYMPTTEAAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKTKELHRLSAPWGNCSDT--FRPVPYIYNEHYSPEGCHRNCFQLKVLEICGCGDPRFPLPSEEHRH--CNAKSKIDRQCLSNLTSDSGGYHHLHEQCECRQPCHEKVFETAYSASAWPSQNF--KIGTDCPAVSDIFNDTEACTEYYRQNTAYIEIYYEQLNFESLKETAGYTLVNLFSDFGGNIGLWIGFSVITFAEFAE 714
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Match: unc-8 (Degenerin unc-8 [Source:UniProtKB/Swiss-Prot;Acc:Q21974]) HSP 1 Score: 142.124 bits (357), Expect = 1.761e-35 Identity = 99/320 (30.94%), Postives = 156/320 (48.75%), Query Frame = 1
Query: 502 KTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPST---GIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKT---YNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKI--QCLLQVTSDFNDYLNV---CNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
+TR + Y L +F+L+CSF + C +E+ F + +YGNC+TFN +N S + K SR+ ++ L N + ++P+T G+RL E P+ +G + P GF +S G+ ++ R GNC + FR YN Y+ + C C Q + C C D F L + H C+ SKI QCL +TSD Y ++ C C C+ + S + WP+ ++ + D + FN T + RQN + + IY E +++ + + Y N SD GG + L++GFSV+T EF E
Sbjct: 408 ETRRNLSYTLNEFVLRCSFNSKDCSMERDFKLHVDPEYGNCYTFN----FNDSVEL-KNSRAGPMYGLRLLLN-VHQSDYMPTTEAAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKTKELHRLSAPWGNCSDT--FRPVPYIYNEHYSPEGCHRNCFQLKVLEICGCGDPRFPLPSEEHRH--CNAKSKIDRQCLSNLTSDSGGYHHLHEQCECRQPCHEKVFETAYSASAWPSQNF--KIGTDCPAVSDIFNDTEACTEYYRQNTAYIEIYYEQLNFESLKETAGYTLVNLFSDFGGNIGLWIGFSVITFAEFAE 715
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Fly
Match: ppk8 (gene:FBgn0052792 transcript:FBtr0307180) HSP 1 Score: 77.411 bits (189), Expect = 1.188e-14 Identity = 101/425 (23.76%), Postives = 185/425 (43.53%), Query Frame = 1
Query: 292 LQSEPIDFPSITFCNLNPLRYSQL-NLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFN------------PYNHYNRS-----YIIN----------------------KRSR----SEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIY--GMNLPPGFETSIGIIPTKIR-----RKVDIKGN-CKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLT 1410
+ +EP FP++T CNLN ++ + S S++ QL R+ V D E+V +++ +++ +LN + ++ C F + + +LF P+++++ G C FN PY+H N S + +N +R++ S GL +T +Q D Y S G ++ P E P + G+ L PG ET + I P+KI R VD + C + + + + YT++ C+ CL + C C F + N N IC K +C+ + F + + +C C + + + SF+ A +Y R D P+ + +++ ++++ V +Y +D +++ Q + +FLS +GG + L+LGFS L+
Sbjct: 105 IANEP--FPAVTICNLNQALAERVEHFSNDSVEFAMLQLLCRRKV---DVELVK--TNDSRWEEFILN--------ISQPCNSMVIHCRFGADDYECARLFHPIVTDE-GLCCVFNMLHPRFMYRKRVPYSHRNISLPEGFHAVNWHAELGYRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDVQADAYYCSSSSSIGFKIALHSPN--ESPNVRETGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRRCLFHNELKLRWFAHYTQRNCVAECLSGWLIRHCGC--VTFYMPRLNANDTICPLH-KRECVELIR--FRTIIAMESCLDECLPSCFDL--SFS---AIAYSTRISLDGFRETPSNGGWNFTDAYVERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFLGFSFLS 501
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Fly
Match: ppk8 (gene:FBgn0052792 transcript:FBtr0307179) HSP 1 Score: 68.9366 bits (167), Expect = 3.989e-12 Identity = 84/364 (23.08%), Postives = 153/364 (42.03%), Query Frame = 1
Query: 487 LNETSKTRFE-----MGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFN------------PYNHYNRS-----YIIN----------------------KRSR----SEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIY--GMNLPPGFETSIGIIPTKIR-----RKVDIKGN-CKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLT 1410
L +T+ +R+E + ++ C F + + +LF P+++++ G C FN PY+H N S + +N +R++ S GL +T +Q D Y S G ++ P E P + G+ L PG ET + I P+KI R VD + C + + + + YT++ C+ CL + C C F + N N IC K +C+ + F + + +C C + + + S A +Y R D P+ + +++ ++++ V +Y +D +++ Q + +FLS +GG + L+LGFS L+
Sbjct: 14 LVKTNDSRWEEFILNISQPCNSMVIHCRFGADDYECARLFHPIVTDE-GLCCVFNMLHPRFMYRKRVPYSHRNISLPEGFHAVNWHAELGYRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDVQADAYYCSSSSSIGFKIALHSPN--ESPNVRETGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRRCLFHNELKLRWFAHYTQRNCVAECLSGWLIRHCGC--VTFYMPRLNANDTICPLH-KRECVELIR--FRTIIAMESCLDECLPSCFDLSFS-----AIAYSTRISLDGFRETPSNGGWNFTDAYVERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFLGFSFLS 364
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Fly
Match: ppk26 (gene:FBgn0035785 transcript:FBtr0332797) HSP 1 Score: 55.4546 bits (132), Expect = 9.804e-8 Identity = 101/499 (20.24%), Postives = 185/499 (37.07%), Query Frame = 1
Query: 166 RNHPLLKTLWCIAFILCTILT-IRQLYNLSSSYFSYPLNTVIRLQSEP---IDFPSITFCNLNPLRYSQLNLSKP--SLQEFFKQLENRQFVKDNDNEM---VSRLYDENLFKKLLLNETSK------TRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFN---PYNHYNRSYIINK------------------------------RSRSEGLFITFYL-------QNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIK---GNCKEGHGFRKT----YNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF------NDYLNV---------CNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQN--LSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFL 1425
+ PLL+ L+ I+ ++ ++ T ++ N+ + + P+ +S P I FP++T C R N + +++F + + D + VS++ + +L L N+T + E+ D L C + + +F ++ G CF+FN P + II R G YL D+ +G P G ++ PG + +P E I I P I +K N ++ + F+K Y ++Y++ C CL N +KC C F + +N+N +C D+ ++C Q + +N CNC +C + Y + S A++ D K + + E RQ +S V I+ ++ + + Y +FL++ GG L L++G S+L+ E +
Sbjct: 89 KKRPLLERLFWISVLVLSVFTCVKLTLNIWDKWNNNPVIVSFAEKSTPVWQIPFPAVTVCPETKTRREIFNFTDSYHQVRDFQSNVSGIVDLSDKQKGLYGAVSQVCEPHLHDVTLGNKTRRGMEIIDALTEVSPHFDDTYLNCKWRNSPVKCSDIFHKFVTED-GVCFSFNSLSPAEIFRAEGIIPDFIFREENRLSMDWNVEDGYSASADTSPYPNRVLGPGARAGLYLFMGGAEIDFDDMCRG--PVQGFKILLHTPGDVAQVSKQYFRIPFDQEVLISIRPKIITTSDGLKHYEPNRRQCY-FQKERELRYFNIYSQSNCELECLANFTLTKCGCVK--FSM-PRNVNMPVCG-DASLKCYNQAEDELLLREFTQGLVNAGENTRGETECNCLPSCTSIAYEAEISQADF-----------DYKTVINTDSPEGKEEQSKRQGMKMSRVSIFFKEAQFLTSRRSELYGTTDFLANCGGLLGLFMGVSMLSIVELI 568
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Fly
Match: rpk (gene:FBgn0022981 transcript:FBtr0078859) HSP 1 Score: 54.6842 bits (130), Expect = 1.635e-7 Identity = 60/286 (20.98%), Postives = 107/286 (37.41%), Query Frame = 1
Query: 664 IINKRSRSEGLFI---TFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDI------KGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF------------------NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISL 1440
+++ +RS G+F+ +F + D +G P G ++ P + + +P G E I + P I I + C H + VYT+ C CL N +KC C +N++ +C D KI C + + + CNC AC + Y + S A + D++++ T + +S + IY + + + Y FL++ GG L++GFS+L+ E + +L
Sbjct: 283 VLSAGARS-GIFLALQSFKQEVDYACRG--PVQGFKVLLHAPDDVPQVSKQFVRIPMGKEVLIAVKPNMITMSSGIAEYHPVRRQCFLSHERSLRFFKVYTESNCQLECLANFTLTKCGCVKFSMP---RNVDMPVCGED-KIHCYDRAERELLVREFKRVKALNAGRENSRSVESACNCMPACTSLVYNTEISQANF-----------DLEEMLVAEGDTEFLKEYPGSQMSRLSIYFKQSQFITSKRSELYGMTEFLANCGGIFGLFMGFSILSLVEMIYHFTL 550
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Fly
Match: rpk (gene:FBgn0022981 transcript:FBtr0305313) HSP 1 Score: 51.2174 bits (121), Expect = 2.245e-6 Identity = 50/234 (21.37%), Postives = 85/234 (36.32%), Query Frame = 1
Query: 811 MNLPPGFETSIGIIPTKIRRKVDI------KGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF------------------NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISL 1440
+ +P G E I + P I I + C H + VYT+ C CL N +KC C +N++ +C D KI C + + + CNC AC + Y + S A + D++++ T + +S + IY + + + Y FL++ GG L++GFS+L+ E + +L
Sbjct: 338 VRIPMGKEVLIAVKPNMITMSSGIAEYHPVRRQCFLSHERSLRFFKVYTESNCQLECLANFTLTKCGCVKFSMP---RNVDMPVCGED-KIHCYDRAERELLVREFKRVKALNAGRENSRSVESACNCMPACTSLVYNTEISQANF-----------DLEEMLVAEGDTEFLKEYPGSQMSRLSIYFKQSQFITSKRSELYGMTEFLANCGGIFGLFMGFSILSLVEMIYHFTL 556
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Zebrafish
Match: asic1c (acid-sensing (proton-gated) ion channel 1c [Source:NCBI gene;Acc:407670]) HSP 1 Score: 124.405 bits (311), Expect = 8.040e-30 Identity = 122/476 (25.63%), Postives = 198/476 (41.60%), Query Frame = 1
Query: 64 MKEIKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNHPLLKT-LWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEP-IDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQL----ENRQFVKDN--DNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF-----NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
MK +E + NN++ + +IF H + LW ++F+ L + + YF +P T + + P + FP++TFCNLN R+S++ +K L + L EN Q + D E+++ L ++ F + + T F G+ + + +LQCSF GE+C L F + +YG C+TFN N K GL I +Q DEYL + + GI++ + G + PGF+T + + G+C+ Y S Y+ AC C + C C ++ +C + C DF NDY C C+ CN T Y + S + P+ + K + FN T + N+ + I+ E +Y++I Q +AY+ L DIGG + L++G SVLT E +
Sbjct: 4 MKGDSEDSIESMRPSNLQVFANNSTLHGMSHIFAYGHMTFRRFLWTLSFMGSLGLLMYVCMDRVYYYFEFPHVTKLDEVAAPNLTFPAVTFCNLNEFRFSKI--TKNDLYHVGELLALLNENYQIANPHLADPEVLTLLKEKASFNGFKPKQFNMTDFYNRTGHDINEMLLQCSFRGEECF--PLNFTTIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLYLPPPWGDCRSAP-MDSEYFSTYSITACRIDCETRYLLENCNC-----RMVHMPGTSTVCTPEQYKDCA-DPALDFLVEKDNDY---CVCDTPCNMTRYGKELSMVKIPSKASAKY-------LAKKFNKTEQ---YITDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFD 455
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Zebrafish
Match: asic4a (acid-sensing (proton-gated) ion channel family member 4a [Source:NCBI gene;Acc:407668]) HSP 1 Score: 122.094 bits (305), Expect = 4.574e-29 Identity = 121/477 (25.37%), Postives = 207/477 (43.40%), Query Frame = 1
Query: 133 TSCLAIGNIFIRNH-PLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEP-IDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFV--KDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIR--LHFQEPGALEMPEIY--GMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQC------LLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPA---SSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKMITGKSGNEK 1494
+S I +IF+ + +TLW +AF++ L + Q + SY +P T + ++ P + FP++T CN+N R+S L + L N + K+ D + L + + N T G+QL++ + C+F G+ C E F ++ +YG C+TFN +R + GL I +Q D+YL + + GIR +H Q+ E P I+ G + PGF+T + ++ GNC+ Y+ AC C + +C+C ++ + IC T S I+C LLQ +S + C C CN T Y + S + P+ + Y R ++ +D + R N + I+ E +Y+ I Q +AY L DIGG + L++G SVLT E L+ + + + +++ + ++K
Sbjct: 48 SSLHGINHIFVSGRLGVRQTLWALAFLVSLALFLYQAAKCAISYLEHPHVTALNEEATPEMVFPAVTICNINRFRFSALTDAD------IYHLANLTGLPPKNKDGHKPTDLEYPAPDMQDIFNRT-------GHQLEEMLKSCNFSGQNCSAED--FTVVYTRYGKCYTFNGNKTTSRK--TKQGGMGNGLEIMLDIQQDDYLPIWKETNETSLEAGIRVQIHSQD----EPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRSTSEQMIPGYDTYSISACRLRCETLEVLRECKC-----RMVHMPGDANIC-TPSDIKCVDKALALLQKSSG-----DTCFCETPCNLTRYGKELSMVKIPSKGSARYLSRKYDKSED-------------YIRDNFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGASVLTILEILDYVYEVIKHRLERLLRPQRDDKK 479
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Zebrafish
Match: asic1a (acid-sensing (proton-gated) ion channel 1a [Source:NCBI gene;Acc:791696]) HSP 1 Score: 112.079 bits (279), Expect = 7.112e-26 Identity = 110/447 (24.61%), Postives = 178/447 (39.82%), Query Frame = 1
Query: 190 LWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPI-DFPSITFCNLNPLRYSQLNLSKP-SLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEM-------GYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCY------DAVF--QLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTY-LC 1458
LW + F+ + + Y YP T + + P+ FP++T CNLN +R+S++ + E L +R V++ +V E L K F M G+ +KD +L C F G C+ E F ++ +YG C+TFN + K GL I +Q DEYL + S GI++ + G + PGF+T + ++ G+CK Y Y+ AC C + C C DA + + K H D L++ SD+ C+C CN T Y+ + SF + P+ + K S + +N+ + ++ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + + + Y LC
Sbjct: 50 LWVVFFLSSLTFLMYVCIDRIQFYLEYPHVTKLDEITTPVMVFPAVTICNLNSIRFSRITRNDLYHAGELLALLNSRHEVREA--HLVEESVMEVLKSKTDFRSFKPRHFNMWEFYNRTGHDIKDMLLSCQFRGSPCRPED--FSVVFTRYGKCYTFNS-GETGPPRVSVKGGMGNGLEIMLDIQQDEYLPVWGESDESSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQEQRLVYLPAPWGSCKSTPP-SSDYFRAYSISACRTDCETRYLVENCNCRMVHMPGDAPYCTPVLYKECAHPALDF------LVETDSDY------CSCETPCNITRYSKELSFVKIPSKASVKYLAKKY----------SKSEKYITENVMVLDVFFEALNYETIEQRKAYEVAGLLGDIGGQMGLFIGASILTILELFDYLYEVMKYRLC 468
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Zebrafish
Match: asic4b (acid-sensing (proton-gated) ion channel family member 4b [Source:NCBI gene;Acc:407667]) HSP 1 Score: 109.383 bits (272), Expect = 9.691e-25 Identity = 105/441 (23.81%), Postives = 175/441 (39.68%), Query Frame = 1
Query: 184 KTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSE-PIDFPSITFCNLNPLRYSQL---------NLSK-PSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIRLHFQEPGALEMPEIY--GMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTD----SKIQCLLQVTSDFNDYL-NVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAI 1434
+TLW +A ++ L + Q +++Y P +R ++ + FP+IT CN+N R+S L NL+ P + Q+ N ++ R G+QL+D + C+F G+ C E F ++ +YG C+TFN + + + GL + +Q DEYL + + GIR+ E P I+ G + PGF+T + ++ GNC+ Y+ AC C + +C C + H+ D D SKI+C+ + + + C C CN T Y + S + P+ + + + R N + I+ E +Y+ I Q +AY L DIGG + L++G S+LT E L+ I
Sbjct: 70 QTLWGLALLVSLGLFLYQATWSAATYLERPHLAALREETRRELTFPAITLCNVNRFRFSALTDADIYHLANLTGLPPKSRKGHRPSELQYPPPNMLDIFQR---------------------TGHQLEDMLKSCNFSGQNCSSED--FSVVYTRYGKCYTFN--GNKTSPKRVRQGGTGNGLEMMLDIQQDEYLPIWRETNETTLEAGIRVQIHSQN--EPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRASSEPVIPGYDTYSVSACRLHCESTQVQRECNC----------RMVHMPGDADICAPSKIKCVDKALASLQKSTGDSCPCETPCNLTRYGKELSMVKIPSRGSARYLSRKYQ----------KSEEYIRDNFLILDIFFEALNYETIEQKKAYDIAGLLGDIGGQMGLFIGASILTILEILDYI 463
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Zebrafish
Match: asic1b (acid-sensing (proton-gated) ion channel 1b [Source:NCBI gene;Acc:407672]) HSP 1 Score: 105.145 bits (261), Expect = 2.077e-23 Identity = 114/488 (23.36%), Postives = 197/488 (40.37%), Query Frame = 1
Query: 115 TSMLNNTSCLAIGNIFIRNH--PLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVI-RLQSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLN---ETSKTRFEMG-------YQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF-----NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTY---LCSKMITGKSGN 1488
+ S ++F+ + + + LW + F+L + + Q+ + Y Y T++ ++ + FP+IT CN N R SQL+ S F L Y++N+ + L + +RF + +++ D +L+C+F G++C E + + +YG C+TFN I K GL I +Q DEYL F +++H Q EP ++ G + PGF+T + ++ G+CK +N+ Y+ AC C + C C ++ + C + +C DF NDY C C CN T Y + SF P+ + K + +N T + N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + + + + C+K +S N
Sbjct: 67 ATFFGGCSLHGANHVFVEDKKFSIRQGLWALVFLLAISMFLLQVVDRVIYYLQYDYVTLLDERNAKNMTFPAITLCNYNTFRRSQLSYSD---LLFMGPLLG---------------YEDNMAPGIPLAPEPDRQGSRFSLAEFFNRTRHRMDDMLLECNFAGKECGAEH--WREIFTRYGKCYTFNSGQDGRPLLITTKGGMGNGLEIMLDIQQDEYLPVWGETDETTFEAGIKVQIHTQDEPPFIDQ---LGFGVAPGFQTFVSCQEQRLTYLPPPWGDCKATPIDSDFFNT-YSITACRIDCETRYLVENCNC-----RMVHMPGDAPYCTPEQYKECA-DPALDFLVERDNDY---CVCETPCNMTRYGKELSFVRIPSKASAKY-------LAKKYNKTEQ---YISDNIMVLDIFFEALNYETIEQKKAYELAGLLGDIGGQMGLFIGASILTILELFDYLYEVIKFKLCRCAKKKHQRSNN 511
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Xenopus
Match: lhx1 (LIM homeobox 1 [Source:Xenbase;Acc:XB-GENE-482482]) HSP 1 Score: 120.553 bits (301), Expect = 1.248e-29 Identity = 86/290 (29.66%), Postives = 141/290 (48.62%), Query Frame = 1
Query: 61 EMKEIKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNHPLLKTLWCI--AFILCTILTIRQLYNLSSSYFSYPLNTVIRL-QSEPIDFPSITFCNLNPLRYSQLNLS---KPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNE--------TSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYN--------RSYIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKI 864
EMK +K + L + + L +TS I NIF H + +W + +F LC L Q + +Y++YP + I L S + FP++T CNLN +R S L S SLQ+ ++ +R+ + N + S DEN+ N+ + + EMG+QL+D ++ C+F G++C F ++ K+GNC+TFN + I K GL + ++Q EY++ + GIRL + + PE G+N+PPG ET IG++ ++
Sbjct: 14 EMKVVKPPYDANTLRKLGRTTLQHTSAHGIPNIFRSKHWFRRMVWLVFVSFALCCALW--QCTQMVLTYYTYPSHEKIMLISSAKLKFPAVTICNLNSVRLSSLGRSFSMSNSLQDSGLEMTHRRNRSHHMN-VTSDSVDENVLYASAFNKFASEFNQLPDEQKIEMGHQLEDMLIFCNFHGQECN-SSFFSGFINYKFGNCYTFNSQKSVDIRGNQIRVDPLNITKAGFMYGLHLELFIQQIEYVRDMTHAAGIRLLVHDQAQMPFPEDEGVNVPPGAETEIGMMKVQL 299
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Xenopus
Match: ASIC1 (acid sensing ion channel subunit 1 [Source:NCBI gene;Acc:100489966]) HSP 1 Score: 121.324 bits (303), Expect = 1.086e-28 Identity = 115/464 (24.78%), Postives = 197/464 (42.46%), Query Frame = 1
Query: 184 KTLWCIAFI-----LCTILTIRQLYNLSSSYFSYPLNTVIRLQSEP-IDFPSITFCNLNPLRYSQLNLSKP-SLQEFFKQLENRQFVKDN---DNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCY------DAVF---QLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE-AISLITTYLCSKMITGKS 1482
+ +W + F+ L + T R +Y YF YP T + S P + FP++TFCNLN R+S++ + E L NR + D+ D +++ L D+ F+ + F G+ +++ +L C + GE+C ++ F P+ + +YG C+TFN + + K GL + +Q DEYL F +++H Q EP ++ G + PGF+T + ++ G+CK + Y+ AC C + C C DA + +LY + C D + L++ +DF C C CN T Y + S + P+ + + + + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + A ++ LC GK
Sbjct: 42 RLIWVLCFLGSLSLLLYVCTERIIY-----YFEYPHVTKLDEISTPRMIFPAVTFCNLNEFRFSRVTKNDLYHAGELLSLLNNRYELPDSQLADEKVMEILQDKANFRNFKPKPFNMREFYDRTGHDIREMLLSCKYRGEECSVDD-FVPVFT-RYGKCYTFNSGRNGRSPLVTTKGGTGNGLELMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQ---LGFGVAPGFQTFVSCQEQRLTYLPPPWGDCKSS-AMDSEFFDTYSISACRIDCETRYLVENCNCRMVHMPGDAAYCTPELYKE------C-ADPALDFLVEKDNDF------CVCETPCNMTRYGKELSMVKIPSKASARYLAKKY----------NKSEQYIAENILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTVLELFDYAYEVLRYKLCGGAKCGKD 471
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Xenopus
Match: ASIC1 (acid sensing ion channel subunit 1 [Source:NCBI gene;Acc:100489966]) HSP 1 Score: 120.939 bits (302), Expect = 1.440e-28 Identity = 110/455 (24.18%), Postives = 191/455 (41.98%), Query Frame = 1
Query: 184 KTLWCIAFI-----LCTILTIRQLYNLSSSYFSYPLNTVIRLQSEP-IDFPSITFCNLNPLRYSQLNLSKP-SLQEFFKQLENRQFVKDN---DNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTY-LCSKMITGKS 1482
+ +W + F+ L + T R +Y YF YP T + S P + FP++TFCNLN R+S++ + E L NR + D+ D +++ L D+ F+ + F G+ +++ +L C + GE+C ++ F P+ + +YG C+TFN + + K GL + +Q DEYL F +++H Q EP ++ G + PGF+T + ++ G+CK + Y+ AC C + C C +++ I + + + D ND+ C C CN T Y + S + P+ + + + + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + + Y LC GK
Sbjct: 42 RLIWVLCFLGSLSLLLYVCTERIIY-----YFEYPHVTKLDEISTPRMIFPAVTFCNLNEFRFSRVTKNDLYHAGELLSLLNNRYELPDSQLADEKVMEILQDKANFRNFKPKPFNMREFYDRTGHDIREMLLSCKYRGEECSVDD-FVPVFT-RYGKCYTFNSGRNGRSPLVTTKGGTGNGLELMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQ---LGFGVAPGFQTFVSCQEQRLTYLPPPWGDCKSS-AMDSEFFDTYSISACRIDCETRYLVENCNCR----MVHMPGICYFLVEKD-------------NDF---CVCETPCNMTRYGKELSMVKIPSKASARYLAKKY----------NKSEQYIAENILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTVLELFDYAYEVRIYKLCGGAKCGKD 455
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Xenopus
Match: ASIC1 (acid sensing ion channel subunit 1 [Source:NCBI gene;Acc:100489966]) HSP 1 Score: 119.013 bits (297), Expect = 4.804e-28 Identity = 110/459 (23.97%), Postives = 194/459 (42.27%), Query Frame = 1
Query: 184 KTLWCIAFI-----LCTILTIRQLYNLSSSYFSYPLNTVIRLQSEP-IDFPSITFCNLNPLRYSQLNLSKP-SLQEFFKQLENRQFVKDN---DNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCY------DAVF---QLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKMI 1470
+ +W + F+ L + T R +Y YF YP T + S P + FP++TFCNLN R+S++ + E L NR + D+ D +++ L D+ F+ + F G+ +++ +L C + GE+C ++ F P+ + +YG C+TFN + + K GL + +Q DEYL F +++H Q EP ++ G + PGF+T + ++ G+CK + Y+ AC C + C C DA + +LY + D + L++ +DF C C CN T Y + S + P+ + + + + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + + C++ +
Sbjct: 45 RLIWVLCFLGSLSLLLYVCTERIIY-----YFEYPHVTKLDEISTPRMIFPAVTFCNLNEFRFSRVTKNDLYHAGELLSLLNNRYELPDSQLADEKVMEILQDKANFRNFKPKPFNMREFYDRTGHDIREMLLSCKYRGEECSVDD-FVPVFT-RYGKCYTFNSGRNGRSPLVTTKGGTGNGLELMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQ---LGFGVAPGFQTFVSCQEQRLTYLPPPWGDCKSS-AMDSEFFDTYSISACRIDCETRYLVENCNCRMVHMPGDAAYCTPELYKEC-------ADPALDFLVEKDNDF------CVCETPCNMTRYGKELSMVKIPSKASARYLAKKY----------NKSEQYIAENILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTVLELFDYAYEVRMLSCAETL 469
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Xenopus
Match: cspg4 (chondroitin sulfate proteoglycan 4 [Source:Xenbase;Acc:XB-GENE-5893460]) HSP 1 Score: 114.39 bits (285), Expect = 2.344e-26 Identity = 114/459 (24.84%), Postives = 190/459 (41.39%), Query Frame = 1
Query: 184 KTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQ-SEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQL--ENR-------QFVKDNDNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQC---LLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASS----YEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAI-SLITTYLCSKMIT 1473
+T W +AF + N + S+P +T ++L+ S+ + FP++TFCN NP+R+ +L+ S ++ L NR + + ++ + +L D LF + F +G+QL+D +L C + GE C F + +YG C+ FN K GL I +Q DEYL F +++H Q EP ++ G + PGF+T + ++ G C+ + VY+ AC C I C C ++ + C + +C L + ++ D N C C CN T Y + S + P+ + EK+F K I N + ++ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + I +IT C+ + T
Sbjct: 66 RTFWFLAFFTSLGFFLSWSSNRLLYWLSFPSHTRVQLEWSKELAFPAVTFCNNNPVRFHRLSKSDLYFAGYWLGLLFANRTARPMLAELLPEDRRKWFQKLADFRLFLPPRNFDGISVGFMDRLGHQLEDMLLSCKYRGEACGPHN--FSTVFTRYGKCYMFNSGQDGRPVLTTVKGGAGNGLEIMLDIQQDEYLPIWGDTEETTFEAGVKVQIHSQSEPPFIQE---LGFGVAPGFQTFVATQEQRLTYLPSPWGACRFSE-LGSDFFPVYSISACRIDCETRYIVENCGC-----KMVHMPGDAPFCTPEQYKECAEPALDLLAE-KDGGN-CVCTIPCNVTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYILDNILVLD--------------VFFEALNYETIEQRKAYEVAGLLGDIGGQMGLFIGASILTILELFDYIYEVITEGFCAHIQT 497
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Mouse
Match: Asic2 (acid-sensing (proton-gated) ion channel 2 [Source:MGI Symbol;Acc:MGI:1100867]) HSP 1 Score: 119.013 bits (297), Expect = 4.396e-28 Identity = 122/477 (25.58%), Postives = 199/477 (41.72%), Query Frame = 1
Query: 70 EIKRKKLEDVLGEEATSMLNNTSCL-AIGNIFIRNHPLL--KTLWCIAFILCTILTIRQLYNLSSSYFSYP-LNTVIRLQSEPIDFPSITFCNLNPLRYSQLNLSKP-SLQEFFKQLENRQFVKD---NDNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCL---LQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAI 1434
++K E L + + NTS L I +IF+ PL + LW +AF+ L + + S YFSY + V + ++ + FP++T CNLN R+S+L + E L+ + D D ++ L + FK + S F +G+ LKD +L C F G++C + F + KYG C+ FN K GL I +Q DEYL F +++H Q EP ++ G + PGF+T + ++ G C+ + VY+ AC C I C C ++ + C + +C L + ++ + N C C CN T Y + S + P+ + K + FN + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + I
Sbjct: 2 DLKESPSEGSLQPSSIQIFANTSTLHGIRHIFVYG-PLTIRRVLWAVAFVGSLGLLLVESSERVSYYFSYQHVTKVDEVVAQSLVFPAVTLCNLNGFRFSRLTTNDLYHAGELLALLDVNLQIPDPHLADPTVLEALRQKANFKHYKPKQFSMLEFLHRVGHDLKDMMLYCKFKGQECGHQD--FTTVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQE---LGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSE-MGLDFFPVYSITACRIDCETRYIVENCNC-----RMVHMPGDAPFCTPEQHKECAEPALGLLAEKDS--NYCLCRTPCNLTRYNKELSMVKIPSKTSAKY-------LEKKFN---KSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYI 454
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Mouse
Match: Asic1 (acid-sensing (proton-gated) ion channel 1 [Source:MGI Symbol;Acc:MGI:1194915]) HSP 1 Score: 111.309 bits (277), Expect = 2.017e-25 Identity = 119/459 (25.93%), Postives = 188/459 (40.96%), Query Frame = 1
Query: 178 LLKTLWCIAF-----ILCTILTIRQLYNLSSSYFSYPLNTVI-RLQSEPIDFPSITFCNLNPLRYSQLNLSKPSL---QEFFKQLENRQFVKDN---DNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCY------DAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE-AISLITTYLCSK 1464
L + LW + F +L + T R Y YF Y T + + + + FP++T CNLN R+SQ+ SK L E L NR + D D + + L D+ F+ + F G+ ++D +L C F GE C E F ++ +YG C+TFN K GL I +Q DEYL F +++H Q EP ++ G + PGF+T + ++ G C ++S Y+ AC C + C C DA Y + C D + L++ ++ C C CN T Y + S + P+ + K + FN + + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + A +I LC +
Sbjct: 41 LKRALWALCFLGSLAVLLCVCTERVQY-----YFCYHHVTKLDEVAASQLTFPAVTLCNLNEFRFSQV--SKNDLYHAGELLALLNNRYEIPDTQMADEKQLEILQDKANFRSFKPKPFNMREFYDRAGHDIRDMLLSCHFRGEACSAED--FKVVFTRYGKCYTFNSGQDGRPRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQ---LGFGVAPGFQTFVSCQEQRLIYLPSPWGTCNAVTMDSDFFDS-YSITACRIDCETRYLVENCNCRMVHMPGDAP---YCTPEQYKEC-ADPALDFLVEKDQEY------CVCEMPCNLTRYGKELSMVKIPSKASAKY-------LAKKFNKSEQ---YIGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHRLCRR 466
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Mouse
Match: Asic2 (acid-sensing (proton-gated) ion channel 2 [Source:MGI Symbol;Acc:MGI:1100867]) HSP 1 Score: 110.923 bits (276), Expect = 2.962e-25 Identity = 115/461 (24.95%), Postives = 180/461 (39.05%), Query Frame = 1
Query: 145 AIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNT-VIRLQSEPIDFPSITFCNLNPLRYSQLN------------------LSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDY-LNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAI 1434
A G F R + LW +AF L + N + S+P +T V R S + FP++T CN NPLR+ +L+ ++P + E + E R+ + +L D LF E F +G+QL+D +L C + GE C F + KYG C+ FN K GL I +Q DEYL F +++H Q EP ++ G + PGF+T + ++ G C+ + VY+ AC C I C C ++ + C + +C + N C C CN T Y + S + P+ + K + FN + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + I
Sbjct: 78 AAGGSFQR-----RALWVLAFCTSLGLLLSWSSNRLLYWLSFPSHTRVHREWSRQLPFPAVTVCNNNPLRFPRLSKGDLYYAGHWLGLLLPNRTARPLVSELLRGDEPRR-------QWFRKLADFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSCKYRGELCGPHN--FSSVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQE---LGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSE-MGLDFFPVYSITACRIDCETRYIVENCNC-----RMVHMPGDAPFCTPEQHKECAEPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPSKT-------SAKYLEKKFN---KSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYI 505
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Mouse
Match: Asic4 (acid-sensing (proton-gated) ion channel family member 4 [Source:MGI Symbol;Acc:MGI:2652846]) HSP 1 Score: 105.916 bits (263), Expect = 1.175e-23 Identity = 106/421 (25.18%), Postives = 167/421 (39.67%), Query Frame = 1
Query: 235 QLYNLSSSYFSYP-LNTVIRLQSEPI-DFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFV--KDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQEPGALEMPEIY--GMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTY---NSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFND-YLNVCNCNFACNTTTYTIKQSFAEWP---ASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAI 1434
Q +L+ Y + P L + P+ FP++T CN+N R+S L S + F L N + KD D + L +LN T G+QL D + C+F G C F ++ +YG C+TFN S GL I +Q +EYL F +++H QE E P I+ G + PGF+T + ++ GNC+ R+ S Y+ AC C + + +C C ++ N IC + I+C C C CN T Y + S + P ++ Y R +N ++ R+N + ++ E + + + Q AY L D+GG + L++G S+LT E L+ I
Sbjct: 84 QAASLARGYLTRPHLVAMDPAAPAPVAGFPAVTLCNINRFRHSAL-----SDADIF-HLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRT-------GHQLADMLKSCNFSGHHCSASN--FSVVYTRYGKCYTFN--ADPQSSLPSRAGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQE----EPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRAESELREPELQGYSAYSVSACRLRCEKEAVLQRCHC-----RMVHMPGNETICPPNIYIECADHTLDSLGGGSEGPCFCPTPCNLTRYGKEISMVKIPNRGSARYLARKYN-------------RNETYIRENFLVLDVFFEALTSEAMEQQAAYGLSALLGDLGGQMGLFIGASILTLLEILDYI 465
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Mouse
Match: Asic1 (acid-sensing (proton-gated) ion channel 1 [Source:MGI Symbol;Acc:MGI:1194915]) HSP 1 Score: 105.531 bits (262), Expect = 1.621e-23 Identity = 114/468 (24.36%), Postives = 189/468 (40.38%), Query Frame = 1
Query: 115 TSMLNNTSCLAIGNIFIRNHPLLK-TLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVI-RLQSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQEPGALEMPEI--YGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQC---YDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE-AISLITTYLCSK 1464
+ N+ + ++F+ P + LW +AF++ + Q+ + + Y SYP T++ + + + FP++TFCN N +R SQL S P L L + +D + F N RF ++L+D +L CS+ G C F ++ +YG C+TFN K GL I +Q DEYL F +++H Q+ E P I G + PGF+T + ++ G C ++S Y+ AC C + C C + Y + C D + L++ ++ C C CN T Y + S + P+ + K FN + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + A +I LC +
Sbjct: 64 VAFANSCTLHGASHVFVEGGPGPRQALWAVAFVIALGAFLCQVGDRVAYYLSYPHVTLLDEVATTELVFPAVTFCNTNAVRLSQL--SYPDLLYLAPML---GLDESDDPGVPLAPPGPEAFSGEPFN---LHRFYNRSCHRLEDMLLYCSYCGGPCGPHN--FSVVFTRYGKCYTFNSGQDGRPRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQD----EPPFIDQLGFGVAPGFQTFVSCQEQRLIYLPSPWGTCNAVTMDSDFFDS-YSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQYKEC-ADPALDFLVEKDQEY------CVCEMPCNLTRYGKELSMVKIPSKASAKYLAK-------KFN---KSEQYIGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHRLCRR 499
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Match: sp|Q21974|UNC8_CAEEL (Degenerin unc-8 OS=Caenorhabditis elegans OX=6239 GN=unc-8 PE=2 SV=1) HSP 1 Score: 142.124 bits (357), Expect = 2.234e-34 Identity = 99/320 (30.94%), Postives = 156/320 (48.75%), Query Frame = 1
Query: 502 KTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPST---GIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKT---YNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKI--QCLLQVTSDFNDYLNV---CNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
+TR + Y L +F+L+CSF + C +E+ F + +YGNC+TFN +N S + K SR+ ++ L N + ++P+T G+RL E P+ +G + P GF +S G+ ++ R GNC + FR YN Y+ + C C Q + C C D F L + H C+ SKI QCL +TSD Y ++ C C C+ + S + WP+ ++ + D + FN T + RQN + + IY E +++ + + Y N SD GG + L++GFSV+T EF E
Sbjct: 407 ETRRNLSYTLNEFVLRCSFNSKDCSMERDFKLHVDPEYGNCYTFN----FNDSVEL-KNSRAGPMYGLRLLLN-VHQSDYMPTTEAAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKTKELHRLSAPWGNCSDT--FRPVPYIYNEHYSPEGCHRNCFQLKVLEICGCGDPRFPLPSEEHRH--CNAKSKIDRQCLSNLTSDSGGYHHLHEQCECRQPCHEKVFETAYSASAWPSQNF--KIGTDCPAVSDIFNDTEACTEYYRQNTAYIEIYYEQLNFESLKETAGYTLVNLFSDFGGNIGLWIGFSVITFAEFAE 714
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Match: sp|Q25011|FANA_CORAP (FMRFamide-activated amiloride-sensitive sodium channel OS=Cornu aspersum OX=6535 PE=2 SV=1) HSP 1 Score: 125.946 bits (315), Expect = 3.480e-29 Identity = 122/512 (23.83%), Postives = 208/512 (40.62%), Query Frame = 1
Query: 184 KTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQ-SEPIDFPSITFCNLNPL-----RYSQLNLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKG----------FIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEG--HGFRKTYNSVYTKQACLYVCLQNVIFSKCQC----------YDAVFQLYLK-----NINHLICDTDSK-----------IQCLLQVTSDFND---YLNVCNCNFACNTTTYTIKQSFAEWPASSYE----KRFFNDIKD-----------------IYPNFNITSNENSHA-----------------------RQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLIT 1446
K +W + I QL L Y + + + ++ S P+ +PS++ CN+ P+ R N +L + + ++ +F +D+ + Y+ L + +K ++ + L+D ++ C F E C + F Y NCFTFN + ++ GL + F ++ D+ L G + S G+R+ PG++ P +G+++PPG+ +S+G+ R GNC +G ++ YT ACL +C Q +I +C C Y+A F +K N NH D + + C + + N+ Y C C C+ T+Y S + WP Y+ +RFF + +P+ + +SH RQN+ + IY+ED S E Q+ AY + +DIGGTL L++G SVLT E +E + +T
Sbjct: 67 KVIWALLVIAGFTAATLQLSLLVRKYLQFQVVELSEIKDSMPVQYPSVSICNIEPISLRTIRRMYFNNESQNLITWLRFIQKFRFEQDSFMNSIRAFYEN-------LGQDAK---KLSHNLEDMLMHCRFNRELCHVSN-FSTFFDGNYFNCFTFNS----GQRLQMHATGPENGLSLIFSVEKDDPLPGTYGVYNFDNNILHSAGVRVVVHAPGSMPSPVDHGIDIPPGYSSSVGLKAILHTRLPYPYGNCTNDMLNGIKQY---KYTFFACLQLCKQRLIIQRCGCKSSALPEVPSYNATFCGVIKDWQEINRNHSNEDHNQSEEDRAFIPTPYLACEEREQKNLNNDRTYELSCGCFQPCSETSYLKSVSLSYWPLEFYQLSAVERFFKQERQAGQNHFMKTAYEYLEKLAHPSQKHLARNDSHMDDILSKSYSLSEKEMAKEASDLIRQNMLRLNIYLEDLSVVEYRQLPAYGLADLFADIGGTLGLWMGISVLTIMELIELVIRLT 560
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Match: sp|Q708S6|ASI1C_DANRE (Acid-sensing ion channel 1C OS=Danio rerio OX=7955 GN=asic1c PE=1 SV=1) HSP 1 Score: 124.405 bits (311), Expect = 6.069e-29 Identity = 122/476 (25.63%), Postives = 198/476 (41.60%), Query Frame = 1
Query: 64 MKEIKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNHPLLKT-LWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEP-IDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQL----ENRQFVKDN--DNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF-----NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
MK +E + NN++ + +IF H + LW ++F+ L + + YF +P T + + P + FP++TFCNLN R+S++ +K L + L EN Q + D E+++ L ++ F + + T F G+ + + +LQCSF GE+C L F + +YG C+TFN N K GL I +Q DEYL + + GI++ + G + PGF+T + + G+C+ Y S Y+ AC C + C C ++ +C + C DF NDY C C+ CN T Y + S + P+ + K + FN T + N+ + I+ E +Y++I Q +AY+ L DIGG + L++G SVLT E +
Sbjct: 4 MKGDSEDSIESMRPSNLQVFANNSTLHGMSHIFAYGHMTFRRFLWTLSFMGSLGLLMYVCMDRVYYYFEFPHVTKLDEVAAPNLTFPAVTFCNLNEFRFSKI--TKNDLYHVGELLALLNENYQIANPHLADPEVLTLLKEKASFNGFKPKQFNMTDFYNRTGHDINEMLLQCSFRGEECF--PLNFTTIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLYLPPPWGDCRSAP-MDSEYFSTYSITACRIDCETRYLLENCNC-----RMVHMPGTSTVCTPEQYKDCA-DPALDFLVEKDNDY---CVCDTPCNMTRYGKELSMVKIPSKASAKY-------LAKKFNKTEQ---YITDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFD 455
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Match: sp|Q19038|DEL1_CAEEL (Degenerin del-1 OS=Caenorhabditis elegans OX=6239 GN=del-1 PE=2 SV=1) HSP 1 Score: 125.176 bits (313), Expect = 7.382e-29 Identity = 94/357 (26.33%), Postives = 153/357 (42.86%), Query Frame = 1
Query: 376 PSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNC--KEGHGFRKTYNSV-YTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFN----DYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFL 1425
P +E+ +QL + D ++ E + K+ + R +GY + I CSF G++C I+ F + +GNC+TFN + + ++ S GL + ++ + +YL +TG+R+ P+ +G + P G +S GI I R GNC K+ R Y Y + C C Q I +KC C D + K CD+ + T + C C C YT S A+WP+ S + N KD NS+ R++ + + IY E SY+ + + +Y W N ++D+GG L+LG S+++ EFL
Sbjct: 284 PLRKEYMEQLTQLGYGNMTDQVAITTQAKEKMILKMSGLHPQR-RAALGYGKSELIKMCSFNGQQCNIDTEFKLHIDPSFGNCYTFNA--NPEKKLASSRAGPSYGLRLMMFVNSSDYLP-TTEATGVRIAIHGKEECPFPDTFGYSAPTGVISSFGISLRNINRLPQPYGNCLQKDNPQSRSIYKGYKYEPEGCFRSCYQYRIIAKCGCADPRYPKPWKR--SAWCDSTNTTTLNCLTTEGAKLSTKENQKHCKCIQPCQQDQYTTTYSAAKWPSGSIQTSCDNHSKDC----------NSYLREHAAMIEIYYEQMSYEILRESESYSWFNLMADMGGQAGLFLGASIMSVIEFL 624
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Match: sp|Q1XA76|ASIC1_CHICK (Acid-sensing ion channel 1 OS=Gallus gallus OX=9031 GN=ASIC1 PE=1 SV=1) HSP 1 Score: 122.865 bits (307), Expect = 1.619e-28 Identity = 114/461 (24.73%), Postives = 190/461 (41.21%), Query Frame = 1
Query: 178 LLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVI-RLQSEPIDFPSITFCNLNPLRYSQLNLSKP-SLQEFFKQLENRQFVKDN---DNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF-----NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE-AISLITTYLCSKMITGKSGNEK*TD 1503
L + +W + F+ L N YF YP T + + + + FP++TFCNLN R+S++ + E L NR + D D + + L D+ F+ + F G+ +++ +L C F GE+C E F ++ +YG C+TFN I K GL I +Q DEYL + + GI++ + + G + PGF+T + ++ G+CK G + Y++ Y+ AC C + C C ++ + C + +C DF N+Y C C CN T Y + S + P+ + K + + +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + A +I LC + K+ TD
Sbjct: 42 LKRVVWALCFMGSLALLALVCTNRIQYYFLYPHVTKLDEVAATRLTFPAVTFCNLNEFRFSRVTKNDLYHAGELLALLNNRYEIPDTQTADEKQLEILQDKANFRNFKPKPFNMLEFYDRAGHDIREMLLSCFFRGEQCSPED--FKVVFTRYGKCYTFNAGQDGKPRLITMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPLIDQLGFGVAPGFQTFVSCQEQRLIYLPPPWGDCKATTGDSEFYDT-YSITACRIDCETRYLVENCNC-----RMVHMPGDAPYCTPEQYKECA-DPALDFLVEKDNEY---CVCEMPCNVTRYGKELSMVKIPSKASAKYLAKKY----------NKSEQYIGENILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHRLCRRGKCRKNHKRNNTD 480
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Match: A0A267F1V4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031795g2 PE=3 SV=1) HSP 1 Score: 399.823 bits (1026), Expect = 5.363e-129 Identity = 206/458 (44.98%), Postives = 284/458 (62.01%), Query Frame = 1
Query: 118 SMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPIDFPSITFCNLNPLRYSQLNL-SKPSLQEFFKQLENRQF-VKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSY-IINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLI--CDTDSKIQCLLQV--TSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENS-HARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKM 1467
++L+NTS LAI NI R+HP+ KTLW IAF +C ILTIRQLY+LS +YFS P +T+I+L +P +FPS+T CN NPLR S ++L +P LQ F LE + + V DN +++++ D F +L+ N T + R MGYQ+ D ILQCSF G++C K F L+ YG+CFTFN + +I K R GL +T YL+ +EYL+ FIPS+GI++H E G+L PE G ++PPGF+TSIG+ I R KG+C +G GF + + YT AC +CL + + C CYD +Y N+ + C T+ ++ CL+ SD D C+C C + +T KQS +EWP SYE R F D+ D+ P N+ AR+NL N+ +YV+ + I + +AY DN+LSDIGGTL L+LGFSVLTGFE LEA +LI YLC K+
Sbjct: 83 ALLSNTSLLAISNIVKRSHPVFKTLWAIAFTVCLILTIRQLYSLSRTYFSDPKSTIIQLSYKPFEFPSVTVCNHNPLRRSMVSLFGQPDLQRFIAGLETKNYSVVDNGTQLMTQQVDWMRFHRLISNHTPEQRLRMGYQMSDLILQCSFAGQRCNT-KHFSVSLTKTYGSCFTFNGWQSAMAGRPVIGKNGREHGLILTLYLELEEYLQNFIPSSGIKVHIHEFGSLAFPETTGFSVPPGFQTSIGMSLRMINRINRPKGSCHDGEGFLQNHGFKYTYNACTMLCLYDRVHKLCGCYDRANAVYYSNLKARLKPCQTEEQLSCLMNTVYASDQGDL--KCDCQLPCEESHFTFKQSLSEWPTDSYEMRLFGDLVDVKPKVADLKNQTKLAARRNLLNLVVYVDGVMAEHIIEKQAYAIDNYLSDIGGTLGLFLGFSVLTGFELLEASALIMAYLCGKI 537
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Match: A0A267F1U6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031795g1 PE=3 SV=1) HSP 1 Score: 399.438 bits (1025), Expect = 5.660e-129 Identity = 206/458 (44.98%), Postives = 284/458 (62.01%), Query Frame = 1
Query: 118 SMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPIDFPSITFCNLNPLRYSQLNL-SKPSLQEFFKQLENRQF-VKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSY-IINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLI--CDTDSKIQCLLQV--TSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENS-HARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKM 1467
++L+NTS LAI NI R+HP+ KTLW IAF +C ILTIRQLY+LS +YFS P +T+I+L +P +FPS+T CN NPLR S ++L +P LQ F LE + + V DN +++++ D F +L+ N T + R MGYQ+ D ILQCSF G++C K F L+ YG+CFTFN + +I K R GL +T YL+ +EYL+ FIPS+GI++H E G+L PE G ++PPGF+TSIG+ I R KG+C +G GF + + YT AC +CL + + C CYD +Y N+ + C T+ ++ CL+ SD D C+C C + +T KQS +EWP SYE R F D+ D+ P N+ AR+NL N+ +YV+ + I + +AY DN+LSDIGGTL L+LGFSVLTGFE LEA +LI YLC K+
Sbjct: 83 ALLSNTSLLAISNIVKRSHPVFKTLWAIAFTVCLILTIRQLYSLSRTYFSDPKSTIIQLSYKPFEFPSVTVCNHNPLRRSMVSLFGQPDLQRFIAGLETKNYSVVDNGTQLMTQQVDWMRFHRLISNHTPEQRLRMGYQMSDLILQCSFAGQRCNT-KHFSVSLTKTYGSCFTFNGWQSAMAGRPVIGKNGREHGLILTLYLELEEYLQNFIPSSGIKVHIHEFGSLAFPETTGFSVPPGFQTSIGMSLRMINRINRPKGSCHDGEGFLQNHGFKYTYNACTMLCLYDRVHKLCGCYDRANAVYYSNLKARLKPCQTEEQLSCLMNTVYASDQGDL--KCDCQLPCEESHFTFKQSLSEWPTDSYEMRLFGDLVDVKPKVADLKNQTKLAARRNLLNLVVYVDGVMAEHIIEKQAYAIDNYLSDIGGTLGLFLGFSVLTGFELLEASALIMAYLCGKI 537
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Match: A0A267EQY0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig025217g1 PE=3 SV=1) HSP 1 Score: 375.941 bits (964), Expect = 1.203e-119 Identity = 199/466 (42.70%), Postives = 284/466 (60.94%), Query Frame = 1
Query: 91 EDVLGEEATSMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPIDFPSITFCNLNPLRYSQLNLSKPS-LQEFFKQLENRQF-VKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNR-SYIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQL-YLKNINHL-ICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENS-HARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKMI 1470
ED + ++L+N+S LAI NI RNHP+LKTLW IA LC IL+IRQLY+L+ +Y +P +T I L +P DFPS+TFCN NPLR S++ L+ PS LQ FF L +R + V DN +++++ D F+KL+ N + R MGYQ DFILQC+F G+KC + +F L+ YGNCFTFN + + K R GL +T +L+ DEYL FIPS G+++ EPG++ PE G ++PPGF++SIG+ KI R +C++G F TY YT AC+ C + + KC CYD +L Y ++ H+ C ++ ++ C++ V + C C C ++Y QS +EWP SYE R F D+ D+ P + NE AR+NL N+ +Y++ + + + +Y DN+LSDIGGTL L+LGFSVLTGFE LEA +L+ Y+C K+I
Sbjct: 91 EDSIKGFMDALLSNSSLLAISNIVKRNHPVLKTLWAIALCLCLILSIRQLYSLTRTYLGHPKSTTIELSYKPFDFPSVTFCNHNPLRRSRVELNGPSDLQSFFSDLLSRNYSVADNGTQLMTQQSDWLKFEKLISNISVLDRLSMGYQHGDFILQCNFAGKKCDPD-MFSVSLTKTYGNCFTFNGWQSVRGFERPVAKNGREHGLIMTLFLELDEYLPNFIPSAGVKVQLHEPGSMGFPEYSGFSVPPGFQSSIGVSLKKITRLDHQNDHCEDGEKFYATYGIKYTYSACMARCKHDRVRQKCGCYDLANKLFYANHVRHMQPCQSEKELSCMIDVEYSGEEGNLNCGCLLPCQESSYKYGQSLSEWPTDSYEARLFGDLMDVKPKISSLKNETKILARRNLLNLLVYMDGLMTEHVIEKNSYAVDNYLSDIGGTLGLFLGFSVLTGFELLEASALVLAYVCGKII 555
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Match: A0A1I8IQQ3 (E3 ubiquitin-protein ligase OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 386.341 bits (991), Expect = 1.695e-117 Identity = 202/458 (44.10%), Postives = 276/458 (60.26%), Query Frame = 1
Query: 118 SMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPIDFPSITFCNLNPLRYSQLNL-SKPSLQEFFKQLENRQF-VKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSY-IINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLI--CDTDSKIQCLLQV--TSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENS-HARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKM 1467
++L+NTS LAI NI R+HP+ KTLW IAF +C ILTIRQLY+LS +YFS P +T+I+L +P +FPS+T CN NPLR S ++L +P LQ F LE + + V DN +++ T + R MGYQ+ D ILQCSF G++C K F L+ YG+CFTFN + +I K R GL +T YL+ +EYL+ FIPS+GI++H E G+L PE G ++PPGF+TSIG+ I R KG+C +G GF + + YT AC +CL + + C CYD +Y N+ + C T+ ++ CL+ SD D C+C C + +T KQS +EWP SYE R F D+ D+ P N+ AR+NL N+ +YV+ + I + +AY DN+LSDIGGTL L+LGFSVLTGFE LEA +LI YLC K+
Sbjct: 83 ALLSNTSLLAISNIVKRSHPVFKTLWAIAFTVCLILTIRQLYSLSRTYFSDPKSTIIQLSYKPFEFPSVTVCNHNPLRRSMVSLFGQPDLQRFIAGLETKNYSVVDNGTQLM----------------TQQQRLRMGYQMSDLILQCSFAGQRCNT-KHFSVSLTKTYGSCFTFNGWQSAMAGRPVIGKNGREHGLILTLYLELEEYLQNFIPSSGIKVHIHEFGSLAFPETTGFSVPPGFQTSIGMSLRMINRINRPKGSCHDGEGFLQNHGFKYTYNACTMLCLYDRVHKLCGCYDRANAVYYSNLKARLKPCQTEEQLSCLMNTVYASDQGDL--KCDCQLPCEESHFTFKQSLSEWPTDSYEMRLFGDLVDVKPKVADLKNQTKLAARRNLLNLVVYVDGVMAEHIIEKQAYAIDNYLSDIGGTLGLFLGFSVLTGFELLEASALIMAYLCGKI 521
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Match: A0A267GP53 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig025217g2 PE=3 SV=1) HSP 1 Score: 219.164 bits (557), Expect = 1.666e-62 Identity = 114/247 (46.15%), Postives = 156/247 (63.16%), Query Frame = 1
Query: 91 EDVLGEEATSMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPIDFPSITFCNLNPLRYSQLNLSKPS-LQEFFKQLENRQF-VKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNR-SYIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLP 822
ED + ++L+N+S LAI NI RNHP+LKTLW IA LC IL+IRQLY+L+ +Y +P +T I L +P DFPS+TFCN NPLR S++ L+ PS LQ FF L +R + V DN +++++ D F+KL+ N + R MGYQ DFILQC+F G+KC + +F L+ YGNCFTFN + + K R GL +T +L+ DEYL FIPS G+++ EPG++ PE G P
Sbjct: 91 EDSIKGFMDALLSNSSLLAISNIVKRNHPVLKTLWAIALCLCLILSIRQLYSLTRTYLGHPKSTTIELSYKPFDFPSVTFCNHNPLRRSRVELNGPSDLQSFFSDLLSRNYSVADNGTQLMTQQSDWLKFEKLISNISVLDRLSMGYQHGDFILQCNFAGKKCDPD-MFSVSLTKTYGNCFTFNGWQSVRGFERPVAKNGREHGLIMTLFLELDEYLPNFIPSAGVKVQLHEPGSMGFPEYSGSQCP 336
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Cavefish
Match: asic1c (acid-sensing ion channel 1C-like [Source:NCBI gene;Acc:103034544]) HSP 1 Score: 118.242 bits (295), Expect = 5.920e-28 Identity = 113/437 (25.86%), Postives = 175/437 (40.05%), Query Frame = 1
Query: 190 LWCIAFILCTILTIRQLYNLSSSYFSYPLNTVI-RLQSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLE------NRQFVK----DNDNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF-----NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
LW +A +C L +N SYP T I + + + FP++T CN N R S L + ++ + NRQ + E + RL D + ++ S T +G+QL+D +L+C F GE C F + +YG C+TFN N K GL I +Q DEYL + + GI++ P G + PGF+T + +++ G+CK + S Y+ AC C + C C ++ +C + C DF NDY C C CN T Y + S + P+ + K + FN T + N+ + I+ E +Y++I Q +AY+ L DIGG + L++G SVLT E +
Sbjct: 40 LWLLAMFVCLGLLFTWSWNRILYLMSYPAVTKIYMVWAHNMTFPAVTLCNQNLFRVSSLTKADLYHSGYWMDIMHLNHSVNRQSLAMLKHSRHRERLMRLLDFAGYSPPARHKLSTTEMISRLGHQLEDMLLECRFRGENCSFRN--FTPIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETSYEAGIKVQLHSQSEPPFPNELGFWVTPGFQTFVSTQEQRLQYLPPPWGDCKST-PIDSEFFSTYSITACRIDCETRYLLENCNC-----RMVHMPGTSTVCTPEQYKDCA-DPALDFLVEKDNDY---CVCQTPCNMTRYGKELSMVKIPSKA-------SAKYLAKKFNKTEQ---YIGDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFD 454
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Cavefish
Match: asic1a (acid-sensing ion channel 1A-like [Source:NCBI gene;Acc:103034215]) HSP 1 Score: 115.546 bits (288), Expect = 4.117e-27 Identity = 123/473 (26.00%), Postives = 194/473 (41.01%), Query Frame = 1
Query: 145 AIGNIFIRNHPLLKT-LW------CIAFILCTILTIRQLYNLSSSYFSYP-LNTVIRLQSEPIDFPSITFCNLNPLRYSQLNLSKP-SLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEM-------GYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCY------DAVF---QLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTY-LC 1458
I +IF + L+ LW +AF++C + R L+ Y YP + V + + + FP++T CNLN R+ ++ + E L +R ++D ++ E+L K F M G+ ++D +L C F G C+ E F ++ +YG C+TFN I K GL I +Q DEYL F +++H Q EP ++ G + PGF+T + ++ GNCK G + + Y+ AC C + C C DA + +LY K H D V D NDY C C CNTT Y+ + SF + P+ + K S + N+ + ++ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + + + Y LC
Sbjct: 33 GIAHIFTYDRITLRCCLWLLFFLSSVAFLVCVCVD-RVLF-----YLEYPHVTKVDEVVAPAMVFPAVTLCNLNAFRFGRVTRNDLYHAGELLALLNSRYEIRDV--HLIEESVLESLKTKADFQNFKPRPFNMMEFYNRTGHDIRDMLLSCQFRGSPCRPED--FKVVFTRYGKCYTFNS-GETGPLLISMKGGMGSGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQVHSQDEPPFIDQ---LGFGVAPGFQTFVSCQEQRLVYLPPPWGNCKTG-TLDSDFFTAYSISACRIDCETRYLVENCNCRMVHMPGDAPYCTPELY-KECAHPALD--------FLVERD-NDY---CLCETPCNTTRYSKELSFVKIPSKASAKYLAKKF----------SKSEKYIADNVLVLDVFFEALNYETIEQRKAYEVAGLLGDIGGQMGLFIGASILTILELFDYLYEVAKYKLC 467
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Cavefish
Match: asic1c (acid-sensing ion channel 1C-like [Source:NCBI gene;Acc:103034544]) HSP 1 Score: 114.005 bits (284), Expect = 1.925e-26 Identity = 112/437 (25.63%), Postives = 174/437 (39.82%), Query Frame = 1
Query: 190 LWCIAFILCTILTIRQLYNLSSSYFSYPLNTVI-RLQSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLE------NRQFVK----DNDNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF-----NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
LW +A +C L +N SYP T I + + + FP++T CN N R S L + ++ + NRQ + E + RL D + ++ S T +G+QL+D +L+C F GE C F + +YG C+TFN N K GL I +Q DEYL + + GI++ + G + PGF+T + ++ G+CK + S Y+ AC C + C C ++ +C + C DF NDY C C CN T Y + S + P+ + K + FN T + N+ + I+ E +Y++I Q +AY+ L DIGG + L++G SVLT E +
Sbjct: 58 LWLLAMFVCLGLLFTWSWNRILYLMSYPAVTKIYMVWAHNMTFPAVTLCNQNLFRVSSLTKADLYHSGYWMDIMHLNHSVNRQSLAMLKHSRHRERLMRLLDFAGYSPPARHKLSTTEMISRLGHQLEDMLLECRFRGENCSFRN--FTPIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLQYLPPPWGDCKST-PIDSEFFSTYSITACRIDCETRYLLENCNC-----RMVHMPGTSTVCTPEQYKDCA-DPALDFLVEKDNDY---CVCQTPCNMTRYGKELSMVKIPSKASAKY-------LAKKFNKTEQ---YIGDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFD 472
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Cavefish
Match: asic1c (acid-sensing ion channel 1C-like [Source:NCBI gene;Acc:103034544]) HSP 1 Score: 112.464 bits (280), Expect = 6.642e-26 Identity = 118/476 (24.79%), Postives = 197/476 (41.39%), Query Frame = 1
Query: 64 MKEIKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNH-PLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEP-IDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQL----ENRQFVKDN--DNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF-----NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
MK +E + + N+++ + +IF H + LW ++F+ L + + S Y +P T + + P + FP++TFCNLN R+S++ +K L + L EN Q + + E+++ L ++ F + + T F G+ + + +LQC+F GE C F + +YG C+TFN N K GL I +Q DEYL + + GI++ + G + PGF+T + ++ G+CK + S Y+ AC C + C C ++ +C + C DF NDY C C CN T Y + S + P+ + K + FN T + N+ + I+ E +Y++I Q +AY+ L DIGG + L++G SVLT E +
Sbjct: 4 MKGDSEDSIESIRPSNLQAFANSSTLHGMSHIFAYGHMTFRRLLWTLSFLGSLGLLLVVCMDRVSYYLQFPHITKLDEVAAPNLTFPAVTFCNLNEFRFSKI--TKNDLYHVGELLALLNENYQIANPHLAEPEVLAALKEKGNFVNFKPKQFNMTDFYNRTGHDINEMLLQCTFRGEDCY--PFNFSTIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLQYLPPPWGDCKSTP-IDSEFFSTYSITACRIDCETRYLLENCNC-----RMVHMPGTSTVCTPEQYKDCA-DPALDFLVEKDNDY---CVCQTPCNMTRYGKELSMVKIPSKASAKY-------LAKKFNKTEQ---YIGDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFD 455
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Cavefish
Match: asic1c (acid-sensing ion channel 1C-like [Source:NCBI gene;Acc:103034544]) HSP 1 Score: 112.464 bits (280), Expect = 6.728e-26 Identity = 118/476 (24.79%), Postives = 197/476 (41.39%), Query Frame = 1
Query: 64 MKEIKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNH-PLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEP-IDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQL----ENRQFVKDN--DNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF-----NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
MK +E + + N+++ + +IF H + LW ++F+ L + + S Y +P T + + P + FP++TFCNLN R+S++ +K L + L EN Q + + E+++ L ++ F + + T F G+ + + +LQC+F GE C F + +YG C+TFN N K GL I +Q DEYL + + GI++ + G + PGF+T + ++ G+CK + S Y+ AC C + C C ++ +C + C DF NDY C C CN T Y + S + P+ + K + FN T + N+ + I+ E +Y++I Q +AY+ L DIGG + L++G SVLT E +
Sbjct: 4 MKGDSEDSIESIRPSNLQAFANSSTLHGMSHIFAYGHMTFRRLLWTLSFLGSLGLLLVVCMDRVSYYLQFPHITKLDEVAAPNLTFPAVTFCNLNEFRFSKI--TKNDLYHVGELLALLNENYQIANPHLAEPEVLAALKEKGNFVNFKPKQFNMTDFYNRTGHDINEMLLQCTFRGEDCY--PFNFSTIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLQYLPPPWGDCKST-PIDSEFFSTYSITACRIDCETRYLLENCNC-----RMVHMPGTSTVCTPEQYKDCA-DPALDFLVEKDNDY---CVCQTPCNMTRYGKELSMVKIPSKASAKY-------LAKKFNKTEQ---YIGDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFD 455
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Sea Lamprey
Match: SCNN1A (sodium channel epithelial 1 alpha subunit [Source:HGNC Symbol;Acc:HGNC:10599]) HSP 1 Score: 112.079 bits (279), Expect = 1.880e-26 Identity = 120/480 (25.00%), Postives = 186/480 (38.75%), Query Frame = 1
Query: 166 RNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPIDFPSITFCNLNPLRY-------SQLN-LSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKL--------LLNETSKTRFEMGY--------------------------------QLKDFILQCSFLGEKC---QIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHG---FRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLIC---DTDSKIQCLLQVTSDF-NDYLN-VCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
+ + L W + F + IL + Y+SY + + L + FP+IT C+LNP RY SQL+ ++ +LQ+ + RL + ++ L N T F Y ++DFI C F G C + + P YGNC+TFN N ++ + +K R GL + + ++Y+ G R+ + + E G ++ PGFETS+GI + R D GNC E Y+S YT Q C Q + C C + Y N C +T C ++ F +D L V C C T + + +A WP SS EK FN + + N+++T+ N A+ N +Y + + + I + A LS+IG SL+ G SVL+ E E
Sbjct: 42 KRNKLKTAFWSLLFTVTVILFYYTSALVFLQYYSYTVAVTMGLMFQQSTFPAITVCSLNPYRYEVVQSSLSQLDSMTGQALQQLYGYQPPATKAAGTAAAPGIRLDTGVVLERTGPDTVGFKLCNATGGDCFYQSYGSGVQAVTEWYTFQYVNIMSQVPSYIKQSDDANIEDFIFSCMFSGMPCSDSEYSRFHHP----TYGNCYTFNSANS-SKLWQASKPGRDYGLSLILRTEQNDYIPFLSTVAGARIMVHDQESPPFMEEGGFDMRPGFETSLGIRMLEATRMPDPYGNCTEDGSNVPVLNLYSSAYTVQVPECSCFQLALVEACGC---GYYFYPLPPNASYCSYNNTAWAGHCYYKLYRQFISDELGCVDKCAQPCTTKRFAVTPGYAAWPDSSSEKWIFN-LLSLQNNYSVTTVRNDVAKLN-----VYFRELNMKTISESAATNVIWLLSNIGSQWSLWFGSSVLSWLEVGE 507
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Sea Lamprey
Match: ASIC5 (acid sensing ion channel subunit family member 5 [Source:HGNC Symbol;Acc:HGNC:17537]) HSP 1 Score: 92.0485 bits (227), Expect = 4.125e-20 Identity = 99/457 (21.66%), Postives = 187/457 (40.92%), Query Frame = 1
Query: 103 GEEATSMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQ-SEPIDFPSITFCNLNPLRYSQLNLSKPSLQEF---FKQLENRQFVKDNDNEMVSRLY---DENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNP-YNHYNRSYIINKRSRSEGLFITFYLQNDEYLK----GFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNIN---HLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
+E + ++TS + + W + + + Q+ ++Y+++P +T + L + FP++TFCN N + N S + + + FV +N +++ Y +++L +L + Y +++ L F + F + +YGNC+TFN ++ RS +GL + F +Q +Y + GF GIRL +P E G+++ G + + + TK + G+C + + Y+ CL C +++ C C F +K + H C D+ + L Q +L+ C C + S+A +P+ +R+ + N+++ + R+NL ++ + D +Y I Q + LSDIGG L L++G SV+T E LE
Sbjct: 5 AKETIAFSSSTSLHGVARATSAQSRAQRAFWMMVVVAGVAMAGWQVALRLAAYYAWPTSTSLTLHYVRDLSFPAVTFCNYNRIGSVARNTCIISFEGWTILHDLIPLGLFVANNFTPPITQTYSARNQDLSTTILFVR------RLNYAIRNKTLVSWFFRRHTTPQD--FQHVFTEYGNCYTFNGGFSEEQRSLKQKTAGAGKGLQVLFDVQQWDYWENPELGFT-GVGIRLVVHDPDEPPQVEALGLSIGVGTQAYVSVQHTKSINQQYPWGDCDPSKKLQSP--APYSMARCLQECEADLVERICGCKPFNFPGDIKECSLYQHYHCARDALVHILAQGMCTGGSHLS--QCPVPCLHKNFPSSVSYATFPSLQAAQRYERSL-----NYSLV-----YMRENLLSIDVAYTDLNYALIQQQKTLPESVLLSDIGGQLGLFVGASVITIIEVLE 438
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Sea Lamprey
Match: asic1b (acid-sensing (proton-gated) ion channel 1b [Source:NCBI gene;Acc:407672]) HSP 1 Score: 91.2781 bits (225), Expect = 9.734e-20 Identity = 104/484 (21.49%), Postives = 181/484 (37.40%), Query Frame = 1
Query: 157 IFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQ-SEPIDFPSITFCNLNPLRYSQL------------------------------------------NLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF----NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFL--SDIGGTLSLYLGFSVLTGFEFLEAI 1434
++ R+ + LW +AF+ L + + S P +T + + FP++TFCN NP+R+ +L LS+P Q F + + +F+ + +S + L +L G+ L + +L C F G+ C+ + F + +YG C+TFN K GL I +Q +EYL F +++H Q EP ++ G + PGF+T + ++ G+CK + Y+ AC C + C C ++ + C + +C V ND+ C C CN T Y + S + P+ + K +N T ++ +N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + +
Sbjct: 20 LWPRHAVTRRILWLLAFMAALGLLLAWSADRIQHLLSRPAHTRVSTSWVRGLPFPAVTFCNNNPVRFPRLTKSDLYVAGMWLGLLTHAESQQPQATFAATAANLTANPHMMAGLSEPRRQWFQRMSDFSRFLPPREAPGIS----QGLLDRL------------GHPLDEMVLSCRFCGQDCKPQD--FITVYTRYGKCYTFNSGKGGRPLLTTVKGGMGNGLEIMLDIQQEEYLPVWGENDETSFEAGIKVQIHSQDEPPLIDQ---LGFGVSPGFQTFVSCQEQRLIYLPPPWGDCKSTP-ISSDFFETYSITACRIDCETRYLVENCNC-----RMVHMPGDAPYCTPEQYTECARPVLDVLVKRDNDF---CLCETPCNMTRYGKELSMVKIPSKASAKYLAK-------KYNKT---EAYIAENVLVLDIFFEALNYETIEQKKAYEVAGLLETGDIGGQMGLFIGASILTILEIFDYV 463
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Sea Lamprey
Match: asic1a (acid-sensing (proton-gated) ion channel 1a [Source:NCBI gene;Acc:791696]) HSP 1 Score: 91.2781 bits (225), Expect = 9.809e-20 Identity = 102/456 (22.37%), Postives = 181/456 (39.69%), Query Frame = 1
Query: 115 TSMLNNTSCLAIGNIFIRNH-PLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQ-SEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQEPGALEMPEIY--GMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYL-----NVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDR-SYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
T + ++ I +IF L + +W AF+ + + Q + Y + T + Q S + FP+IT CN N R S++ P + + + + DND ++ + D L + T + G+ + + +L+C + +C F + +YG C+ FN K GL + +Q DEYL +++H Q+ E P ++ G + PGF+T + ++ G+CK + Y+ AC C + C C ++ + C + +C D+L N C C+ CNTT Y + S + P+ + K +N T + + R+N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E +
Sbjct: 49 TEFASESTLHGINHIFAPGEFSLRRAIWACAFLASLGMFLYQSADRIVFYLEHHHVTQLDEQESHLMLFPAITLCNFNSFRRSKVT---PVDKHYAGPILG---IPDNDPDLAT--VDVRLLRAWSRYSTYEFYDRAGHTMDEMLLRCRYRDRECGPTN--FTTVFTRYGKCYMFNSGKGGRPLLTTLKGGTGNGLEMMLDIQQDEYLPVWGETDEISLEAGVKVQIHSQD----EPPFVHQLGFGVAPGFQTFVSCQEQRLIYLPSPWGDCK-ADPINSDFFDTYSITACRIDCETRYVVENCNC-----RMVHMPGDAPYCTPEQYKECADPAL----DFLVEKDNNYCVCDTPCNTTRYGKELSMVKIPSKASAKYLAK-------KYNKTED---YIRENVLVLDIFFEAALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTILEIFD 470
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Sea Lamprey
Match: ASIC5 (acid sensing ion channel subunit family member 5 [Source:HGNC Symbol;Acc:HGNC:17537]) HSP 1 Score: 88.5817 bits (218), Expect = 5.852e-19 Identity = 100/457 (21.88%), Postives = 181/457 (39.61%), Query Frame = 1
Query: 103 GEEATSMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQ-SEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQC--SFLGEKCQIEKLFFPMLSNKYGNCFTFNP-YNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNIN---HLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
+E + ++TS + + W + + + Q+ ++Y+++P +T + L + FP++TFCN N R S L+ + L +K E +S + ++T L IL+ ++ C + F + +YGNC+TFN ++ RS +GL + F +Q +L GF GIRL +P E G+++ G + + + TK + G+C + + Y+ CL C +++ C C F +K + H C D+ + L Q +L+ C C + S+A +P+ +R+ + N+++ + R+NL ++ + D +Y I Q + LSDIGG L L++G SV+T E LE
Sbjct: 12 AKETIAFSSSTSLHGVARATSAQSRAQRAFWMMVVVAGVAMAGWQVALRLAAYYAWPTSTSLTLHYVRDLSFPAVTFCNYNRYRRSSLHGTTDLLAALSILSAG---IKTPHPEYLSGFLWRITLRGYSSPPITQTYSARNQDLSTTILEIDDTYCENSCTPQD--FQHVFTEYGNCYTFNGGFSEEQRSLKQKTAGAGKGLQVLFDVQQKSHLWDYWENPELGFT-GVGIRLVVHDPDEPPQVEALGLSIGVGTQAYVSVQHTKSINQQYPWGDCDPSKKLQSP--APYSMARCLQECEADLVERICGCKPFNFPGDIKECSLYQHYHCARDALVIFLAQGMCTGGSHLS--QCPVPCLHKNFPSSVSYATFPSLQAAQRYERSL-----NYSLV-----YMRENLLSIDVAYTDLNYALIQQQKTLPESVLLSDIGGQLGLFVGASVITIIEVLE 448
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Nematostella
Match: EDO42137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2F2]) HSP 1 Score: 143.28 bits (360), Expect = 8.224e-37 Identity = 127/494 (25.71%), Postives = 210/494 (42.51%), Query Frame = 1
Query: 106 EEATSMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQ-SEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLF---KKLLLNETSKTRFEM----------------GYQLKDFILQCSFLGEKCQ------IEKLFFPMLSNKYGNCFTFNPYNHYNRS----YIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKG-NCKEGHGFRKT-----YNSVYTKQACLYVCLQNVIFSKCQCYD-AVFQLYLKNINHLICD--TDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEK---------RFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLI 1443
E+ L T+ G + + W + + + + QL L + Y S P+ T +L+ ++ +DFP +T CN+N LR S+L P L+ F Q+ N N SR N F + L ET K FE+ +QL+D +L C+F G C+ I + ++ +GNC+ FN +N Y + S GL + L+ +EYL+G G+++ + G L P G+ + PG T I + + RR K +C+ + YN Y+ AC Y CL +C C + ++ +NI +C+ + I CL + F D C +C+ ++ + S A WPA S+E R N I + + S +N++ V +Y + Y + + AY + + LSDIGG + +++G S LT E +E + +I
Sbjct: 13 EQINQFLQETTAHGFGRLGATAGSKWRLYWVMFCLAAYCVFVWQLVGLVNQYNSKPIKTRTQLKHAQKLDFPVVTICNMNVLRASRL---PPKLRTKFDQIINNTNKTSPRNSSNSR----NAFVDPQDLSFEETKK--FEILHAVTAHDDYRELVSAAHQLEDILLSCNFNGVNCRNSKDPTIPTYWTQTWNDNFGNCYMFNSVKTHNGEKVDLYSSSVPGESNGLTLQLNLEQNEYLEGITEVAGMKVTISDQGVLPFPGQQGIRIMPGQSTGIQMTKLQTRRIDPFKNRSCESSNEMSDKNLFFGYNMTYSIMACKYSCLNARKIERCGCTNYNTPEMQKRNIP--LCNRLNSTIIDCLNKAYDTFEDGSCDRECPPSCSEVSFDLTVSSARWPARSFEVTKYAYFLRVRVLNKIASSSSKYFVNS-------ENIAQVHVYYGELDYLLVQETLAYTFMSLLSDIGGQMGMWIGISALTCAELIELVCVI 488
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Nematostella
Match: EDO31696 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX71]) HSP 1 Score: 134.42 bits (337), Expect = 2.570e-34 Identity = 109/377 (28.91%), Postives = 169/377 (44.83%), Query Frame = 1
Query: 388 EFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIE----KLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSE--------GLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIK--GNCKEGHG-------FRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDT--DSKIQCLLQVTSDFNDYLNVCN--CNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLI 1443
E K+LE F +N ++ E L + + MG+Q D + +C++ G C+ K + ++GNCF FNP +NR N RSR GL + +Q +EY+ G + G + PE G + PGF T IG+ I+R VD G+C F++ +N+ Y+K AC+ CL +C+C + F +CDT + ++CL +V + C+ C AC Y + SFA WP+ Y+ +++ D N++ S R N V I+ ++ +Y I + AY+ NFLSDIGG L L++G SV+TG E +E LI
Sbjct: 36 EVTKELEEMGF--ENPEQLSDEYRLEELVSITIAKLSPSDLKPMGHQFDDMVYKCTWRGVDCKANYTQGKYWTSFWHYRFGNCFVFNPSIGWNR----NTRSRLHIYRTGPLNGLQLQLNIQQEEYIDQITKRAGAMIQVFPFGQMPFPEERGTLVAPGFSTDIGLEKMDIKR-VDPHNNGSCVTDEASINTENIFKQKFNTSYSKTACVLSCLAYHQMHECKCMEYRFP------TDSVCDTLNSTIVECLAKVKFKLSRNELGCSTACGPACREEAYRLTSSFAVWPSQRYQNSIIDNLFDGIFNYS-----RSWFRDNYLEVNIFFKELNYF-IEESVAYELVNFLSDIGGQLGLWVGVSVMTGAEVVELALLI 393
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Nematostella
Match: EDO36191 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJB5]) HSP 1 Score: 127.872 bits (320), Expect = 9.146e-32 Identity = 113/498 (22.69%), Postives = 204/498 (40.96%), Query Frame = 1
Query: 127 NNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQ-SEPIDFPSITFCNLNPLRYSQL-------------------------------NLSKPSLQEFFKQLENRQ--FVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQC---SFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEG----LFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCN--CNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKMITGKSGNE 1491
+ TSC IG I + + W + F+ + + Q L +Y + P T + + SE +FPS+T CN+N ++ SQL N K +N + + +N N + R ++ + + L +++T+K + G+ ++ + +C F+ K K + P +YGNC+TFN N + + + S G L + ++ ++Y+ G+++ + + P +G + PG S GI +Q C+ CL N F C C + F+ +K++CL ++ + + C+ C C ++ S +W + SYEK F ++ F N+ S R+N V +Y E+ + + I +Y +N L D+GG L L++G SV+T EFL+ + + YL SKM +GK+ +
Sbjct: 19 DRTSCHGIGQIGGSQSVMWRVSWLMIFLAGLGMVLYQGLTLLDTYLNKPTATAVDITYSEVTNFPSVTICNMNMIKKSQLQHFPQVKRLVDTFNNMTSSNSSLNSSAFMDTNREKAEKDRLSLNTKNSKNKVILNNVNIDMQRYIEDKIVQYLSMSDTTKL-MKAGHVFRELVFRCVWNGFVCNKGDFLKYWRPFWHWRYGNCYTFNQGVDVNGTELPSLASSKPGPMYGLTLDLFIDQEQYIIPLSQEAGVKVLLSDQRNIPFPFTHGFTVQPGVSASAGI------------------------------RQGCMSSCLANNQFKVCNCTEGKFR--------------AKVKCLNNISKKYENGSLGCSKSCPQPCTHYSFRRTISQTQW-SDSYEKTFQRLVRKSDRGFANKMNDASILRKNFLRVKLYYEELNRETITYSLSYPVENLLGDVGGQLGLWIGVSVITCAEFLKLLVDLAWYLASKM-SGKTKTQ 469
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Nematostella
Match: EDO34318 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPS2]) HSP 1 Score: 113.235 bits (282), Expect = 4.582e-27 Identity = 83/276 (30.07%), Postives = 126/276 (45.65%), Query Frame = 1
Query: 499 SKTRFE----MGYQLKDFILQCSFLGEKCQIE----KLFFPMLSNKYGNCFTFNP---YNHYNRSYIINKRSRSE-GLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGN--C-------KEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSK--IQCLLQVTSDFN-DYLN-VCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSN 1251
+K RFE +G+Q + +CS+ G C+ + + NKYGNCF FNP +N R + R+ GL + ++ DEY+ G G + G + PE G+++ PGF TSI + KI R VD GN C + + YN+ Y+K ACL CL C C + F + +CDT +K ++CL +V LN C+ CN TY SF+ WPA +Y+++ ++K P ++ N
Sbjct: 15 AKERFENITRLGHQFDSLVRKCSWRGSDCRANATTGRYWGRFWHNKYGNCFVFNPLIGWNGKKRRALTALRAGPNYGLTLELNVEQDEYIDGLSTKAGAVIQVSPVGYMPFPEEEGIDVSPGFSTSIALTKVKISR-VDAFGNRSCVNEITEKDRENLYHVKYNATYSKTACLNFCLAYNQRKTCNCMEYRFPVE----EEAVCDTMNKTTVECLRRVREMLKMKKLNCTAECSAPCNQETYKTTSSFSMWPALNYKEKINKNMKWKKPEEELSHN 285
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Nematostella
Match: EDO32949 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STM2]) HSP 1 Score: 105.916 bits (263), Expect = 1.264e-24 Identity = 111/454 (24.45%), Postives = 198/454 (43.61%), Query Frame = 1
Query: 115 TSMLNNTSCLAIGNIFIRNHPLL-KTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQ-SEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIK---GNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLI--CDTDSKIQCL--LQVTSDFNDYLNVC-NCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKD-IYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLI 1443
S+ ++T+ I N+F + L K +W + F+ I ++ N Y + P+NTV ++ + I FP++T CN NP+R S + P L + + E + +D + ++ + + ++ I C + G C F + + G C+TFN ++ ++ + L + +Q +EY+ G RL F+E + + + L PG +T +IP +++ + + G C+E + K ++ Y+ AC + C + C C ++Y +I I C + CL L V N N+C C CN T+ + S++++PA N I D + + N T + R N V IY ED + I Q A+ + + IGGTL +++G S++T EF+E + LI
Sbjct: 2 ASLCSSTTMHGISNVFDPSSATLRKGIWSVVFLCSFIFCAYEIGNNVRYYLTKPVNTVFKIDYVDEIKFPAVTICNNNPIRKSWA-ATTPYLPVIMA------YNANPGEEAIPINWDAYNWTGFGFDKLMSSAAHLASEM---IHTCKWKGIYCSAAN--FTLDATFLGGCYTFN----IDQRLMVTGTGMANALHLVLNIQQNEYIGNVRSGAGFRLLFREKHEPPSTDRFVIALQPGTQT---LIPLTMKKLISLPEPFGVCQEKNNL-KMFDK-YSVTACEFECRARLGGKLCGCR----EMYPSSIKTEIPVCLPKAYRDCLNPLLVEISVN---NLCRGCKNPCNKVTFVPRMSYSQYPA--------NHIADSMAMSMNTTRD---FVRDNFLEVEIYFEDIMVEIIEQQEAFSLTSLVGIIGGTLGVFIGASIITVSEFMEFLILI 416
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Medaka
Match: asic4a (acid sensing ion channel subunit family member 4 [Source:NCBI gene;Acc:101159336]) HSP 1 Score: 128.642 bits (322), Expect = 2.269e-31 Identity = 119/488 (24.39%), Postives = 208/488 (42.62%), Query Frame = 1
Query: 127 NNTSCLAIGNIFIRNH-PLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEP-IDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFV--KDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIR--LHFQEPGALEMPEIY--GMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTD----SKIQCLLQVTSDFN-DYLNVCNCNFACNTTTYTIKQSFAEWPA---SSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKMITGKSGNEK*TDICILYIS 1524
N+ S I +IF+ + +TLW +AF+ L + + SY +P T + ++ P + FP++T CN+N R+S L + L N + K+ D + L + + N T G+QL++ ++ C+F G+ C E F ++ +YG C+TFN +R + GL I +Q DEYL + + GIR +H Q+ E P I+ G + PGF+T + ++ GNC+ + Y+ AC +C N + C+C + H+ D SKI C+ + + + + C C CN T Y + S + P+ + Y R ++ +D + R N + I+ E +Y+ I Q +AY L DIGG + L++G S+LT E L+ + + + +++ + +K + +S
Sbjct: 46 NSCSLHGINHIFVSGRLGIRQTLWALAFLTSLALFLYHAAKCAISYLEHPHVTALNEEATPEMVFPAVTICNINRFRFSALTDAD------IYHLANLTGLPPKNRDGHKPTDLMYPAPDMQDIFNRT-------GHQLEEMLMSCNFSGQNCSAED--FSVVYTRYGKCYTFNGNKTASRK--TKQGGMGNGLEIMLDIQQDEYLPIWRETNETSLEAGIRVQIHSQD----EPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRSTSKEKFPGYDTYSISACRLLCETNEVLRVCKC----------RMVHMPGTADICPPSKISCVDKALAQLQKNSGDTCPCETPCNLTRYGKELSMVKIPSKGSARYLSRKYDKSED-------------YIRDNFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGASILTVLEILDYVFEVIRHRLQRLLRPQKEEKKQPKSAVATVS 489
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Medaka
Match: ENSORLT00000031246.1 (acid sensing ion channel subunit 1 [Source:NCBI gene;Acc:101155423]) HSP 1 Score: 128.642 bits (322), Expect = 2.522e-31 Identity = 127/459 (27.67%), Postives = 195/459 (42.48%), Query Frame = 1
Query: 178 LLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVI-RLQSEPIDFPSITFCNLNPLRYSQLNLSKP-SLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLN---ETSKTR-FEM-------GYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQEPGALEMPEI--YGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDF-----NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTY-LCSKM 1467
L +TLW + F+L + + + YF YP T + + + I FP+ITFCNLN R+S++ + E L R ++D L +EN+ + L E+ K R F M G+ +KD +L CS+ G +C E F ++ +YG C+TFN + K GL + +Q DEYL F +++H QE E P I G + PGF+T + ++ G+CK +NS Y+ AC C + C C ++ + C + +C DF NDY C C CN T Y + SF + P+ + K + FN T + N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + + I Y LC M
Sbjct: 41 LKRTLWILFFMLSVGVLVMVCVDRVQFYFEYPHVTKLDEVAASMIVFPAITFCNLNSFRFSRVTRNDLYHAGELLALLNGRYEIRD------PHLVEENVLQVLRERADFESYKPRSFNMREFYDRTGHDIKDMLLSCSYRGTECSAEN--FKVIFTRYGKCYTFNSGKDGQPLMVTMKGGTGNGLELMLDIQQDEYLPVWGETDETSFEAGIKVQIHTQE----EPPFIDQLGFGVAPGFQTFVSCQEQRLTYLPPPWGDCKSTPMDSDFFNS-YSITACRIDCETRYLVENCNC-----RMVHMPGDAPYCSPEQYKECA-DPALDFLVERDNDY---CVCETPCNLTRYGKELSFVKIPSKASAKY-------LAKKFNKTEQ---YIADNILVLDIFFEALNYETIEQKKAYELAGLLGDIGGQMGLFIGASILTVLELFDYLYEILKYKLCRCM 467
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Medaka
Match: asic1a (acid-sensing ion channel 1 [Source:NCBI gene;Acc:101159102]) HSP 1 Score: 121.709 bits (304), Expect = 3.632e-29 Identity = 120/473 (25.37%), Postives = 197/473 (41.65%), Query Frame = 1
Query: 127 NNTSCLAIGNIFIRNHPLLKT-LWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPI-DFPSITFCNLNPLRYSQLNLSKP-SLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEM-------GYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLK--------GFIPSTGIRLHFQ-EPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCY------DAVF---QLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTY-LC 1458
++++ I +IF +K LW + F+ L + + Y YP T + + PI FP+ITFCNLN R+S++ + E L +R ++D +V E+L K + F M G+ +KD +L C F G +C+ F ++ +YG C+TFN I K GL + +Q DEYL F +++H Q EP +++ G + PGF+T + ++ G+CK ++S Y+ AC C + C C DA + +LY + D + L+Q +DF C C CN T Y + SF + P+ + K + + + N+ + I+ E +Y+ I Q +AY+ L DIGG + L++G S+LT E + + + Y LC
Sbjct: 23 HSSTLHGIAHIFTYERLCIKRCLWLLVFLCSLTLLLYVCVDRIHYYLEYPHVTRLDEVATPIMTFPAITFCNLNAFRFSRVTRNDLYHAGELLALLNHRYEIRDV--HLVEESVLESLKVKADFHNFKPRPFNMREFYDRTGHDIKDMLLSCHFHGTECRPGD--FKVVFTRYGKCYTFNAGGDGRPPLITTKGGMGNGLELMLDIQQDEYLPVWGDTDETSFEAGVKVQIHSQDEPPSIDQ---LGFGVAPGFQTFVSCQEQRLIYLPPPWGDCKVTPMDSDFFDS-YSITACRVDCETRYLVDNCNCRMVYMPGDAPYCSPELYKEC-------ADPALDFLVQRDNDF------CVCETPCNMTRYNKELSFVKIPSKASAKYLAKKY----------NKSEQYIKDNILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTILEIFDYLYEVIKYKLC 464
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Medaka
Match: ENSORLT00000021936.2 (acid-sensing ion channel 1C [Source:NCBI gene;Acc:101174951]) HSP 1 Score: 119.013 bits (297), Expect = 4.206e-28 Identity = 118/478 (24.69%), Postives = 186/478 (38.91%), Query Frame = 1
Query: 67 KEIKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNHP-LLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRL-QSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENR---------QFVKDNDNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYL-----NVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
+E L++ L E + T + IF N + +W +AF+LC L +N SYP+ T I + + + FP++T CN N R S L ++ L N +K++ + RL D + + T +G+QL+D +L+C F GE C F + +YG C+TFN N K GL I +Q DEYL + + GI++ + G + PGF+T + ++ G+CK + S Y+ AC C + C C ++ +C D C D+L N C C CN T Y + S + P+ + K FN T + N+ + I+ E +Y++I Q +AY+ L DIGG + L++G SVLT E +
Sbjct: 21 QESTPSSLQNTLKETTVEFIRRTKVHGLKFIFSPNKSKFQQIIWILAFLLCISLFCTWSWNRIFYLMSYPVVTKIYMVWAHNMSFPAVTLCNKNVFRVSALTKDDLYHSGYWMDLMNPNHTLINRSLSILKESHRPGLLRLLDFRNYAPPPDYSVNTTEMMSRLGHQLEDMLLECKFRGETCTFRN--FSTIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGETDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLQYLPPPWGDCKSTP-IDSEFFSTYSITACRIDCETRYLLENCNC-----RMVHMPGTSTVCTPDQYKDCADPAL----DFLVEKDNNYCVCETPCNMTRYGKELSMVKIPSKASAKYLAK-------KFNKTEQ---YIGDNILVLDIFFEALNYEKIEQKKAYEIAGLLGDIGGQMGLFIGASVLTILEIFD 476
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Medaka
Match: ENSORLT00000035361.1 (acid-sensing ion channel 1C [Source:NCBI gene;Acc:101174951]) HSP 1 Score: 118.627 bits (296), Expect = 5.539e-28 Identity = 118/478 (24.69%), Postives = 186/478 (38.91%), Query Frame = 1
Query: 67 KEIKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNHP-LLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVI-RLQSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENR---------QFVKDNDNEMVSRLYDENLFKKLLLNETSKTRF--EMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPS------TGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYL-----NVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
+E L++ L E + T + IF N + +W +AF+LC L +N SYP+ T I + + + FP++T CN N R S L ++ L N +K++ + RL D + + T +G+QL+D +L+C F GE C F + +YG C+TFN N K GL I +Q DEYL + + GI++ + G + PGF+T + ++ G+CK + S Y+ AC C + C C ++ +C D C D+L N C C CN T Y + S + P+ + K FN T + N+ + I+ E +Y++I Q +AY+ L DIGG + L++G SVLT E +
Sbjct: 21 QESTPSSLQNTLKETTVEFIRRTKVHGLKFIFSPNKSKFQQIIWILAFLLCISLFCTWSWNRIFYLMSYPVVTKIYMVWAHNMSFPAVTLCNKNVFRVSALTKDDLYHSGYWMDLMNPNHTLINRSLSILKESHRPGLLRLLDFRNYAPPPDYSVNTTEMMSRLGHQLEDMLLECKFRGETCTFRN--FSTIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGETDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLQYLPPPWGDCKSTP-IDSEFFSTYSITACRIDCETRYLLENCNC-----RMVHMPGTSTVCTPDQYKDCADPAL----DFLVEKDNNYCVCETPCNMTRYGKELSMVKIPSKASAKYLAK-------KFNKTEQ---YIGDNILVLDIFFEALNYEKIEQKKAYEIAGLLGDIGGQMGLFIGASVLTILEIFD 476
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Match: SMESG000006412.1 (SMESG000006412.1) HSP 1 Score: 976.082 bits (2522), Expect = 0.000e+0 Identity = 475/477 (99.58%), Postives = 476/477 (99.79%), Query Frame = 1
Query: 64 MKEIKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKMITGKSGNEK 1494
MKEIKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQI+KLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFE SIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKMITGKSGNEK
Sbjct: 1 MKEIKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILCTILTIRQLYNLSSSYFSYPLNTVIRLQSEPIDFPSITFCNLNPLRYSQLNLSKPSLQEFFKQLENRQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFLGEKCQIKKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSEGLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFEISIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVFQLYLKNINHLICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKMITGKSGNEK 477
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Match: SMESG000053446.1 (SMESG000053446.1) HSP 1 Score: 104.375 bits (259), Expect = 2.539e-23 Identity = 118/481 (24.53%), Postives = 201/481 (41.79%), Query Frame = 1
Query: 166 RNHPLLKT-LWCIAFILCTILTIRQLYNLSSSYFSYPLNT-VIRLQSEPIDFPSITFCNLNPLRYSQ-LNLSKPSLQEFFKQLE----------------------------NRQFVKDNDNEMVSRLYDENLFKKLLLNETSKT-----RFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSE-GLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKE---------GHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVF-----QLYLKNINHL---ICD----TDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSH--ARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLE 1428
R+ +L++ +W I + + + Q+ + Y ++T V R S ++FP+IT CN NP+ Y + L+++K + F +L+ N+Q N N R DE ++L L T + + G L D ++ C F C F+ + +YGNCFT+N + N+S + + GL + ++ + Y+ + ++GIRL P PE G+ PG S+G+ T +C+ + N YTK+ C+ C Q I CQCY + L +NI+ + +CD T I C + N + NC+ AC +Y+I S WP++ ++ N + + + + NS + + IY E +Y +I + AY++ + +SD GG + L+LG SV FE E
Sbjct: 53 RSQEILRSIMWAIIILGAACVLLYQIQLAVVKFLKYDVSTSVKRNVSNALEFPAITICNQNPVDYKKILSINK----DIFAKLKSWESNAPQNNPMNITITASATSSTTSKGNQQNQMPNINGFGGRTADETYQRQLELQAMMATLNYQQKVQAGMSLDDMLISCFFNNYLCNTSD-FYQFYNFQYGNCFTYNLLS--NKSILQTLEIGPQYGLKMILFINSSAYIPITL-NSGIRLLVHHPTEYPFPEDVGIGAVPGKLNSVGLQLTVATISYPPYNSCQNLTTTQAMELSAYVGQLPNVSYTKEGCMKTCTQKYILMYCQCYHPFYPYNSSMLAYRNISSVDLRMCDINYQTTDAICCANTKIAIMNGTFDCKNCSLACKKNSYSITVSNCNWPSTIAQQSIINQLSGLPAMAYLQQSVNSDNIISTQMMQLEIYFESMTYLDITEQPAYEFVSLISDFGGLMGLWLGLSVAACFEIFE 525
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Match: SMESG000053446.1 (SMESG000053446.1) HSP 1 Score: 103.605 bits (257), Expect = 6.233e-23 Identity = 120/495 (24.24%), Postives = 205/495 (41.41%), Query Frame = 1
Query: 166 RNHPLLKT-LWCIAFILCTILTIRQLYNLSSSYFSYPLNT-VIRLQSEPIDFPSITFCNLNPLRYSQ-LNLSKPSLQEFFKQLE----------------------------NRQFVKDNDNEMVSRLYDENLFKKLLLNETSKT-----RFEMGYQLKDFILQCSFLGEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKRSRSE-GLFITFYLQNDEYLKGFIPSTGIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKE---------GHGFRKTYNSVYTKQACLYVCLQNVIFSKCQCYDAVF-----QLYLKNINHL---ICD----TDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNENSH--ARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSKMI 1470
R+ +L++ +W I + + + Q+ + Y ++T V R S ++FP+IT CN NP+ Y + L+++K + F +L+ N+Q N N R DE ++L L T + + G L D ++ C F C F+ + +YGNCFT+N + N+S + + GL + ++ + Y+ + ++GIRL P PE G+ PG S+G+ T +C+ + N YTK+ C+ C Q I CQCY + L +NI+ + +CD T I C + N + NC+ AC +Y+I S WP++ ++ N + + + + NS + + IY E +Y +I + AY++ + +SD GG + L+LG SV FE E + L M+
Sbjct: 53 RSQEILRSIMWAIIILGAACVLLYQIQLAVVKFLKYDVSTSVKRNVSNALEFPAITICNQNPVDYKKILSINK----DIFAKLKSWESNAPQNNPMNITITASATSSTTSKGNQQNQMPNINGFGGRTADETYQRQLELQAMMATLNYQQKVQAGMSLDDMLISCFFNNYLCNTSD-FYQFYNFQYGNCFTYNLLS--NKSILQTLEIGPQYGLKMILFINSSAYIPITL-NSGIRLLVHHPTEYPFPEDVGIGAVPGKLNSVGLQLTVATISYPPYNSCQNLTTTQAMELSAYVGQLPNVSYTKEGCMKTCTQKYILMYCQCYHPFYPYNSSMLAYRNISSVDLRMCDINYQTTDAICCANTKIAIMNGTFDCKNCSLACKKNSYSITVSNCNWPSTIAQQSIINQLSGLPAMAYLQQSVNSDNIISTQMMQLEIYFESMTYLDITEQPAYEFVSLISDFGGLMGLWLGLSVAACFEIFELLFDTIVTLVKMMV 539
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Match: SMESG000081650.1 (SMESG000081650.1) HSP 1 Score: 86.2705 bits (212), Expect = 1.917e-17 Identity = 132/550 (24.00%), Postives = 210/550 (38.18%), Query Frame = 1
Query: 133 TSCLAIGNIFIRNHPLLKTLWC-------IAFILCTILTIRQLYNLSSSYFSYP-LNTVIRLQSEPIDFPSITFCNLNPLRYSQLNLSKP----SLQEFFKQLEN-----RQFVKDNDNEMVSRLYDENLFKKLLLNETSKTRFEMGYQLKDFILQCSFL--------GEKCQIEKLFFPMLSNKYGNCFTFNPYNHYNRSYIINKR--SRSEGLFITFYLQN-DEY-------LKGFIPSTGIRLHFQEPGALEMPEIY--GMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTYNSV---YTKQACLYVCLQNVIFSKCQCYD------------------------AVFQLYLKNINH-LICDTDSKIQCLLQVTSDFNDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPN-----FNITSNENS-------------------HARQN-------------LSNVFIYVE-DRSYQEIYQIR---AYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAISLITTYLCSK 1464
TS + I P + LW +A I C +L I Q Y Y ++ + ++P FPS++FCNL PL + K S+ E+ KQL+ R+ + ++++ ++ N + L N T ++G+ + ++ C + G C + L++ Y NC TF I+NK+ +++ + + YL + DE +K + TG+RL+ G PEI G+NL PG T I IP + G C + + ++N V Y+++AC LQ + C C D L + NH D +K C LQ +S+ N Y N CN C TY S AEWP S+ F ++D +NIT + S +N +SN F+ ++ R+ +I + + NFLS GG S++ G + E LE LI + SK
Sbjct: 69 TSLRGVPRIAKTRDPKRRFLWIFFVTAFFLACITCIVLLIMQ-------YRQYDVIHQPKTVYNKPTPFPSLSFCNLRPLSSHSIKTLKNNGLNSVSEYLKQLKQSMEDLRKSSNITERKLLTMSWNINSYFLNLPNSTQPN--DLGHDRLEMVMYCLLIYKQGIYNSGIVCDKAGHWVSTLNSIYINCHTF----------IVNKKFTNKTFSMEVVLYLDHADEIYCNDCNEMKIYSQLTGVRLNLHSSGT--YPEIIEKGINLMPGTLTEIKFIPRQWNMMEPPHGKCSKQVSKKISFNKVEFQYSEEACKRKVLQEELAKNCDCVDFNQVPDDLNNYLQHKKICQYLPATPFSNATLSSFNHSQTADYLNKTHCNLQTSSEIN-YQN--KCNSPCTFFTYDTTISSAEWPTKSFHTSFLKSLRDYIQKRMRNFYNITESTRSAWTTIIEELKPYLSLIEKIEKEENVTLNKKLLNDLKFVSNNFLSIQVGRTNFDIILVEEKASVSLTNFLSQTGGIFSIWSGITFFCIVEILELFILIFEEIFSK 594
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Match: SMESG000053477.1 (SMESG000053477.1) HSP 1 Score: 82.4185 bits (202), Expect = 4.647e-17 Identity = 68/274 (24.82%), Postives = 111/274 (40.51%), Query Frame = 1
Query: 691 GLFITFYLQNDEYLKGFIPST---GIRLHFQEPGALEMPEIYGMNLPPGFETSIGIIPTKIRRKVDIKGNCKEGHGFRKTY---------NSVYTKQACLYVCLQNVIFSKCQCYDAVF-----QLYLKNINHL---ICDTDSKIQ---CLLQVTSDF-NDYLNVCNCNFACNTTTYTIKQSFAEWPASSYEKRFFNDIKDIYPNFNITSNE--NSHARQNLSNVFIYVEDRSYQEIYQIRAYKWDNFLSDIGGTLSLYLGFSVLTGFEFLEAI 1434
G+ +T ++ + Y IP T GIR+ P PE G+ PG S+G+ T NCK N YTK+ C+ C Q I C+CY + L +NI+ + +C+ + + C+ + N + NC C T+Y++ S+ WP+ + N ++ + +F NE + + IY + +Y EI + Y + +SD+GG + L+LG SV E E I
Sbjct: 17 GVKMTLFIDSSTY----IPITFNSGIRVLIHHPTEYPFPEDVGIGALPGKLNSVGLFLTAALILPLPHNNCKNMTTLEAMQLSAYVGLMPNVSYTKEGCMKTCTQKFILIYCKCYHPFYPYNSNMLAYRNISSVDLRMCNINYQTTDDICITNIKIGIKNGTFDCTNCTLVCKKTSYSMTVSYCNWPSKIALETIMNKLRS-FSSFASLENEILEPLVLDQVLQIEIYFDSLTYLEISESPTYTVLSLISDLGGQMGLWLGLSVAAFLEIFELI 285 The following BLAST results are available for this feature:
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30004942 ID=SMED30004942|Name=Amiloride-sensitive sodium channel subunit gamma|organism=Schmidtea mediterranea sexual|type=transcript|length=1707bpback to top protein sequence of SMED30004942-orf-1 >SMED30004942-orf-1 ID=SMED30004942-orf-1|Name=SMED30004942-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=478bp MKEIKRKKLEDVLGEEATSMLNNTSCLAIGNIFIRNHPLLKTLWCIAFILback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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