Irregular chiasm C-roughest-like isoform X2

Query:   41 IAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW--------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNI-SCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYH-KFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTC----SFSYGKTIVT-KQIHLLPL 1753
            ++ +V +L+     S  T+     EP++  V+ GQ  VL C L     +V    QW+KD   L        +  R  + GS  +G Y+L     EL D+A Y C   E  LR          +  L ++ PP +                      +I +      N TC + N  P   ++W             T L  +GK +     L+   +D     + +C+ +N+       +P+   T   L + +   + T     + +  GE V F+C +   P  I+ Y W           G +L+E +  +         F    + C +   V   N                   S  +N+ + P+I       T ++IG  V L+C    NP  ++ W K                              NM+ S S     + V + D   Y C A         + V +     P I  E     V  DG   + C + S   P P  I W ++ + L + + ER  +       GV S L    V+++D+ T Y C    SF  G  I+  ++  +LP+
Sbjct:    2 LSLLVWILTLSDTFSQGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIV----QWTKDGLALGMGQGLKAWP-RYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSR--------RAKLTVLIPPEDTRID---------------GGPVILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSMNE------AIPSGKETSIELDVHHPPTV-TLSIEPQTVQEGERVVFTCQATANPE-ILGYRW---------AKGGFLIEDAHESRYETNVDYSFFTEPVSCEVHNKVGSTNV------------------STLVNVHFAPRIVVD-PKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKD---------------------------SNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQYAVRGDG-GKVECFIGS--TPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPV 495          

Query:  812 IHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTC----SFSYGKTIVT-KQIHLLPL 1753
            +  GE V F+C +   P I+  Y W           G +L+E +  +         F    + C +   V   N                   S  +N+ + P+I       T ++IG  V L+C    NP  ++ W K                     +  E  +   ++S+++    + V + D   Y C A         + V +     P I  E     V  DG   + C + S   P P  I W ++ + L + + ER  +       GV S L    V+++D+ T Y C    SF  G  I+  ++  +LP+
Sbjct:   32 VQEGERVVFTCQATANPEIL-GYRW---------AKGGFLIEDAHESRYETNVDYSFFTEPVSCEVHNKVGSTNV------------------STLVNVHFAPRIVVD-PKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMGPRPPG----------SPPEAALSAQVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQYAVRGDG-GKVECFIGS--TPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPV 309          

Query: 1100 LNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKV-EQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSF--SYGKTIVTKQIHLL 1747
            L +L  P  + PF    V+ +G+   L+C VD NP   I W   + GT  +    ++ Y               +I+S            D   Y C A+ +    I K V++   ++P I      T+K  +    SL C+ +  PKP   NIKW   +  +       R  IN + ++     L  K+    D G Y C    S G T++T  + ++
Sbjct: 2331 LEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPN-GTRFSNGPQSYQY---------------LIASNGSFIISKTTREDAGKYRCAAR-NKVGYIEKLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKP---NIKWTMPSGYVV-----DRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIV 2524          

Query:  506 IIWVPENQKLNFTCISKNGSPMPQLMW--------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNI-SCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKF-QVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTC----SFSYGKTIVT-KQIHLLPL 1753
            +I +      N TC + N  P   ++W             T L  +GK +     L+   +D     + +C+ +N+       +P+   T   L + +   + T     + +  GE V F+C +   P I+  Y W           G +L+E +  +         F    + C +   V   N                   S  +N+ + P+I       T ++IG  V L+C    NP  ++ W K                              NM+ S S     + V + D   Y C A         + V +     P I  E     V  DG   + C + S   P P  I W ++ + L + + ER  +       GV S L    V+++D+ T Y C    SF  G  I+  ++  +LP+
Sbjct:   30 VILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSMNEA------IPSGKETSIELDVHHPPTV-TLSIEPQTVQEGERVVFTCQATANPEIL-GYRW---------AKGGFLIEDAHESRYETNVDYSFFTEPVSCEVHNKVGSTNV------------------STLVNVHFAPRIVVD-PKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKD---------------------------SNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQYAVRGDG-GKVECFIGS--TPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPV 395          

Query:   53 VIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLE-IPENVVKIKLQWSKD---MFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTE--LQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQN-------YSLMRLSSDF--HNSNISCKIVNKK--------DYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDN-----CDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNI--GEWVVLSCE-VDSNPQASIRW 1222
             I+L  F  +  S+++ L + PS +  I G+    +C  E  PE +V    QW  +   + G     I   ++GR +    I+    +LH K T   L D+  Y C +   L   E    +  K  L II PP  + F  +  N            SII V EN  LN TC+  N  P P+++W +  +    D  +    +       Y+ + + SD   H   I+C+   K+          LD   P +  TV++L  +N   LR+  N+         ++ S      P  + +Y     + N   Q+   L  RS      IK          +   F + Q DN     C +N +R  N   + KA+    L + YPP      E    SNI  G    + C+ + SNP + I W
Sbjct:    5 AILLWLFGSIHISSQFFL-ESPSNLSTIAGESITFRCSAEKSPEPIVY--SQWKSNTGSLLGYHQEGILPGHQGRFSY---IKQNAEELHLKITHVNLDDDGEYECQM---LHPEE--GPIRAKSFLNIIVPPQLVYFSNYQPN------------SIIAVKENTPLNITCVVPNVKPEPEVLWYMDGKVMSRDVKQASTPHLNKTFTVYTSLVVQSDRNDHGKVITCEAFQKETDIRITTNTTLDVLFPPSDPTVEIL--RNPSALRSGDNV--------TIACSVTGGNPPPDVFWY-----HENKRLQSHSTLDTRSKE----IK----------NIYSFIASQNDNMAEYECRANNSRTGN--PKRKAM---KLEVNYPP---ASVELFGESNIRYGSSANIQCKSLPSNPASQITW 365          

Query:   53 VIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLE-IPENVVKIKLQWSKD---MFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTE--LQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQN-------YSLMRLSSDF--HNSNISCKIVNKK--------DYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDN-----CDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNI--GEWVVLSCE-VDSNPQASIRW 1222
             I+L  F  +  S+++ L + PS +  I G+    +C  E  PE +V    QW  +   + G     I   ++GR +    I+    +LH K T   L D+  Y C +   L   E    +  K  L II PP  + F  +  N            SII V EN  LN TC+  N  P P+++W +  +    D  +    +       Y+ + + SD   H   I+C+   K+          LD   P +  TV++L  +N   LR+  N+         ++ S      P  + +Y     + N   Q+   L  RS      IK          +   F + Q DN     C +N +R  N   + KA+    L + YPP      E    SNI  G    + C+ + SNP + I W
Sbjct:    5 AILLWLFGSIHISSQFFL-ESPSNLSTIAGESITFRCSAEKSPEPIVYS--QWKSNTGSLLGYHQEGILPGHQGRFSY---IKQNAEELHLKITHVNLDDDGEYECQM---LHPEE--GPIRAKSFLNIIVPPQLVYFSNYQPN------------SIIAVKENTPLNITCVVPNVKPEPEVLWYMDGKVMSRDVKQASTPHLNKTFTVYTSLVVQSDRNDHGKVITCEAFQKETDIRITTNTTLDVLFPPSDPTVEIL--RNPSALRSGDNV--------TIACSVTGGNPPPDVFWY-----HENKRLQSHSTLDTRSKE----IK----------NIYSFIASQNDNMAEYECRANNSRTGN--PKRKAM---KLEVNYPP---ASVELFGESNIRYGSSANIQCKSLPSNPASQITW 365          

Query: 1112 YPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQ--TSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEA---------QASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWY 1567
            Y PKI  P E+ TV N G+ + LSC+VD+ P+AS+ WYK       ++R+   Y +  T+T+ +N+ T                  E D+  Y C A           S   K+ K  V  + EEP        +  +     +L C V   P P    IKWY
Sbjct: 4661 YAPKINPPLEDKTV-NGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDST------------------EEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFP---EIKWY 4801          

Query: 1112 YPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQ--TSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEA---------QASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWY 1567
            Y PKI  P E+ TV N G+ + LSC+VD+ P+AS+ WYK       ++R+   Y +  T+T+ +N+ T                  E D+  Y C A           S   K+ K  V  + EEP        +  +     +L C V   P P    IKWY
Sbjct: 4741 YAPKINPPLEDKTV-NGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDST------------------EEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFP---EIKWY 4881          

Query: 1112 YPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQ--TSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEA---------QASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWY 1567
            Y PKI  P E+ TV N G+ + LSC+VD+ P+AS+ WYK       ++R+   Y +  T+T+ +N+ T                  E D+  Y C A           S   K+ K  V  + EEP        +  +     +L C V   P P    IKWY
Sbjct: 5381 YAPKINPPLEDKTV-NGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDST------------------EEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFP---EIKWY 5521          

Query:   41 IAFVVIML-SSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKI-------QRQ--NYSLMRLSS--DFHNSNISCKIVNKKDY--------------------LDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSF--SYGKTIVTKQIH 1741
            +A +V M+ SS +    + ++ +  EP +   ++G    L CR+   +      LQW+KD FGL  S     ++ R  + GS + G Y L      L D+A Y C +         + S      L ++ PP                     +  +I+  E++K+   C+S  G P  ++ W       L+DN +        QR+    S++RL+   + HN+N SC+  N  D                     + G LP             +V + T   I +  H+   V   C +   P   + Y WF+        N E ++    +  ++   + KFH + + C +  SV K                     S++L+I Y P  +   +++  +++G  V L+CEVDSNPQ  I W +                             + ++ +++   F V NE     Y C+A    + +I     V  K  P I  ++    +  D  A + C   S P+    ++ W F   E++  S     ++      GV+S L  +      YG Y C+    YG  +   Q+ 
Sbjct:   10 LATIVGMVRSSPYTSYQNQRFAM--EPQDQTAVVGARVTLPCRVINKQGT----LQWTKDDFGLGTSRDLSGFE-RYAMVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFA--GLTVLVPPEAPKI---------------TQGDVIYATEDRKVEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVE--HS--QVRLECRADANPS-DVRYRWFI--------NDEPIIGGQKTEMVIRNVTRKFHDAIVKCEVQNSVGKSE------------------DSETLDISYAPSFRQRPQSME-ADVGSVVSLTCEVDSNPQPEIVWIQHPS--------------------------DRVVGTSTNLTFSVSNE-TAGRYYCKANVPGYAEISADAYVYLKGSPAIGSQRTQYGLVGD-TARIECFASSVPR--ARHVSWTFNGQEISSESGHDYSILVDAVPGGVKSTLIIRDSQAYHYGKYNCTVVNDYGNDVAEIQLQ 524          

Query:   41 IAFVVIML-SSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKI-------QRQ--NYSLMRLSS--DFHNSNISCKIVNKKDY--------------------LDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSF--SYGKTIVTKQIH 1741
            +A +V M+ SS +    + ++ +  EP +   ++G    L CR+   +      LQW+KD FGL  S     ++ R  + GS + G Y L      L D+A Y C +         + S      L ++ PP                     +  +I+  E++K+   C+S  G P  ++ W       L+DN +        QR+    S++RL+   + HN+N SC+  N  D                     + G LP             +V + T   I +  H+   V   C +   P   + Y WF+        N E ++    +  ++   + KFH + + C +  SV K                     S++L+I Y P  +   +++  +++G  V L+CEVDSNPQ  I W +                             + ++ +++   F V NE     Y C+A    + +I     V  K  P I  ++    +  D  A + C   S P+    ++ W F   E++  S     ++      GV+S L  +      YG Y C+    YG  +   Q+ 
Sbjct:   10 LATIVGMVRSSPYTSYQNQRFAM--EPQDQTAVVGARVTLPCRVINKQGT----LQWTKDDFGLGTSRDLSGFE-RYAMVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFA--GLTVLVPPEAPKI---------------TQGDVIYATEDRKVEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVE--HS--QVRLECRADANPS-DVRYRWFI--------NDEPIIGGQKTEMVIRNVTRKFHDAIVKCEVQNSVGKSE------------------DSETLDISYAPSFRQRPQSME-ADVGSVVSLTCEVDSNPQPEIVWIQHPS--------------------------DRVVGTSTNLTFSVSNE-TAGRYYCKANVPGYAEISADAYVYLKGSPAIGSQRTQYGLVGD-TARIECFASSVPR--ARHVSWTFNGQEISSESGHDYSILVDAVPGGVKSTLIIRDSQAYHYGKYNCTVVNDYGNDVAEIQLQ 524          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW-----TVKTET------GLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKD--YLDGKLPTAVVTVQVLYIKNAVILRTNGNI-DKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITV-SNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLM---CLVESWPKPSPSNIKWYFETSELAIISTERR-YLINKRQL-MGVESKLFFKKVIDSDYGTYTCSF--SYG 1714
            EP +   ++G    L CR  + E V    LQW+KD FGL        ++ R ++ GS + G + L      L D+A Y C +    +  + + S   K  L ++ PP        +    Y           +   E++++   C+S+ G P  ++ W      V T+        L+D+ +I  ++   +    + HN+  +C+  N  D  Y   KL      ++V Y    ++    G +    I  G  V  SC +   P   + Y WF+        N E +    ++  I+   S ++H + + C +  +V K                     SK L+I + P  +     ++V +++G  V + C+V  NP+  I W       S+N+                    + ++   +  K +V +E     Y C+A  + F +I     +  K  P I     + KV+  G+   +   CL  S PK    +I W FE   + + S +   Y+  +  L  GV + L  +    + +G Y C+   SYG
Sbjct:   87 EPQDQTAVVGSRVTLPCR--VMEKVGA--LQWTKDDFGLGQHRNLSGFE-RYSMVGSDEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAK--LTVLVPPEAP----KITQGDY-----------LVTTEDREIELECVSQGGKPAAEITWIDGLGNVLTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAKL-----LLEVKYAPKVIVSVVGGALAGGKIPEGAEVILSCQADANP-HELSYRWFI--------NDELMTGDFTTKMIIHNVSRQYHDAIVKCEVVNAVGKSE------------------QSKKLDISFGPVFRQ--RPVSVEADLGATVSMRCDVAGNPEPEIEW------ISENS--------------------DQVVGVAAELKLKVSSE-TAGRYFCKAVVNGFPEIGAEATLYVKRAPII----TSHKVQFGGVGGRVKIDCLAFSIPK--AEHILWSFEGKIINMSSADPDIYIFEEHHLPEGVRAALIIRDSKATHFGKYNCTVMNSYG 553          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW-----TVKTET------GLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKD--YLDGKLPTAVVTVQVLYIKNAVILRTNGNI-DKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITV-SNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLM---CLVESWPKPSPSNIKWYFETSELAIISTERR-YLINKRQL-MGVESKLFFKKVIDSDYGTYTCSF--SYG 1714
            EP +   ++G    L CR  + E V    LQW+KD FGL        ++ R ++ GS + G + L      L D+A Y C +    +  + + S   K  L ++ PP        +    Y           +   E++++   C+S+ G P  ++ W      V T+        L+D+ +I  ++   +    + HN+  +C+  N  D  Y   KL      ++V Y    ++    G +    I  G  V  SC +   P   + Y WF+        N E +    ++  I+   S ++H + + C +  +V K                     SK L+I + P  +     ++V +++G  V + C+V  NP+  I W       S+N+                    + ++   +  K +V +E     Y C+A  + F +I     +  K  P I     + KV+  G+   +   CL  S PK    +I W FE   + + S +   Y+  +  L  GV + L  +    + +G Y C+   SYG
Sbjct:   87 EPQDQTAVVGSRVTLPCR--VMEKVGA--LQWTKDDFGLGQHRNLSGFE-RYSMVGSDEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAK--LTVLVPPEAP----KITQGDY-----------LVTTEDREIELECVSQGGKPAAEITWIDGLGNVLTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAKL-----LLEVKYAPKVIVSVVGGALAGGKIPEGAEVILSCQADANP-HELSYRWFI--------NDELMTGDFTTKMIIHNVSRQYHDAIVKCEVVNAVGKSE------------------QSKKLDISFGPVFRQ--RPVSVEADLGATVSMRCDVAGNPEPEIEW------ISENS--------------------DQVVGVAAELKLKVSSE-TAGRYFCKAVVNGFPEIGAEATLYVKRAPII----TSHKVQFGGVGGRVKIDCLAFSIPK--AEHILWSFEGKIINMSSADPDIYIFEEHHLPEGVRAALIIRDSKATHFGKYNCTVMNSYG 553          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW-----TVKTET------GLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKD--YLDGKLPTAVVTVQVLYIKNAVILRTNGNI-DKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITV-SNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLM---CLVESWPKPSPSNIKWYFETSELAIISTERR-YLINKRQL-MGVESKLFFKKVIDSDYGTYTCSF--SYG 1714
            EP +   ++G    L CR  + E V    LQW+KD FGL        ++ R ++ GS + G + L      L D+A Y C +    +  + + S   K  L ++ PP        +    Y           +   E++++   C+S+ G P  ++ W      V T+        L+D+ +I  ++   +    + HN+  +C+  N  D  Y   KL      ++V Y    ++    G +    I  G  V  SC +   P   + Y WF+        N E +    ++  I+   S ++H + + C +  +V K                     SK L+I + P  +     ++V +++G  V + C+V  NP+  I W       S+N+                    + ++   +  K +V +E     Y C+A  + F +I     +  K  P I     + KV+  G+   +   CL  S PK    +I W FE   + + S +   Y+  +  L  GV + L  +    + +G Y C+   SYG
Sbjct:   87 EPQDQTAVVGSRVTLPCR--VMEKVGA--LQWTKDDFGLGQHRNLSGFE-RYSMVGSDEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAK--LTVLVPPEAP----KITQGDY-----------LVTTEDREIELECVSQGGKPAAEITWIDGLGNVLTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAKL-----LLEVKYAPKVIVSVVGGALAGGKIPEGAEVILSCQADANP-HELSYRWFI--------NDELMTGDFTTKMIIHNVSRQYHDAIVKCEVVNAVGKSE------------------QSKKLDISFGPVFRQ--RPVSVEADLGATVSMRCDVAGNPEPEIEW------ISENS--------------------DQVVGVAAELKLKVSSE-TAGRYFCKAVVNGFPEIGAEATLYVKRAPII----TSHKVQFGGVGGRVKIDCLAFSIPK--AEHILWSFEGKIINMSSADPDIYIFEEHHLPEGVRAALIIRDSKATHFGKYNCTVMNSYG 553          

Query:   41 IAFVVIMLSSFFLLSNSTKY---------VLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTET--------GLSDNGKIQRQNYSLMRLSSDFHNSN-ISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCS 1702
            + F+ I  + F +   S            V   +P ++ V+ GQP  L C +     VV     W +D   L        Y  R  + G   SG + L  +  EL D+A++ C  I+  +R             L ++ PP +            +G        ++ +     LN TC + N  P   ++W    E          L  +G+ +    +L   +S+  +   I C+  NK    +GK  +  + +Q L + N  +        +P+  G  V F C++   P  +  Y W           G  +++  S +   +     F    + C     V      +NI+RN              +++ + P++    +++ V ++G   V +C    NP  +I W K   G                     V   EN+++       + V + D   Y+C A         K V +     PTI   Q T +  +     + C + S   P P  I W ++ + L   ++ R  +       GV S L    ++ +D+ T Y C+
Sbjct:    6 MEFIFICFACFSMCERSRGLRCTSRPLNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVV----LWLRDGLALGVGRDLSGYP-RYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSR--------PARLTVLVPPDD---------PMITG------GPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKA-VPNGKETSVTIDIQHLPLVNLSVE------PQPVLEGNLVKFHCSAKANPP-VTQYKW---------AKGGSVIKEVSGDTYEVIVDHSFFTEPVSC----EVTNPLGSTNISRN--------------VDVYFGPRMAAEPQSLQV-DLGSDAVFNCAWTGNPSLTIVWMKRGSGV--------------------VLSNENILT------LKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQ-THQAPHGEKGQIKCFIRS--TPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCT 486          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYK-GRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINK----RQLMGVESKLFFKKVIDSDY-GTYTC----SFSYGKTIVT-KQIHLLPL 1753
            EP++  V+LGQ  VL C +     +V    QW+KD  GL     +D+    R  +   +  G Y+L     EL D++LY C   E  LR          +  L ++ PP E   +        +G+ +               N +C+S+   P   + W          V T   L D  ++  ++Y  ++        N +C   N    +  +   A +T+ V +    V L       + +  GE V+F+C +   P  I+ Y W           G  +++ +  +  V KA   F    + C +F +V   N                   S  +++ + P +    + +TV ++   V L+C+   NP  ++ W K   G+S    + N  Y                         + V++ D   Y+C+A           V +     P I  E     V  +    + C + S P P      W     E    +   RY + +     Q   V S L    +++SD+  TY C    SF  G  I++ +++ ++P+
Sbjct:   25 EPADQSVVLGQRVVLSCVVFNYSGIV----QWTKD--GLALGIGEDLRAWPRYRVLRLVDVGQYNLEISAAELSDDSLYECQATEAALRSR--------RAKLTVLIPPDEPVIEGSPEILLTAGVPY---------------NMSCVSRGAKPASVIEWQKDGLPIEGAVSTTEVLPDRKRVTTRSYLPIQPLDTDTGKNFTCVATNLAVPMGKR---ATITLNVHH-PPVVTLSIE---PRSVLEGERVTFTCQATANP-PIMGYKW---------AKGGVVIQGARESVFVTKADHSFFTEPVSCQVFNAVGSTNV------------------SILVDVHFGPILVVEPKPVTV-DVDSDVTLNCKWAGNPPLTLTWTKK--GSSMVLSNNNQLY------------------------LKSVSQADAGQYVCKAIVPRIGVGETEVTLTVNGPPIISSEPFQYAVRGE-RGEVKCYIASTPPPDKIVWAWKENVWEKEKGTLSERYTVEQSKPSAQGGAVLSTLTINNIMESDFQSTYNCTAWNSFGSGTMIISLEEMEIVPV 500          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYK-GRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINK----RQLMGVESKLFFKKVIDSDY-GTYTC----SFSYGKTIVT-KQIHLLPL 1753
            EP++  V+LGQ  VL C +     +V    QW+KD  GL     +D+    R  +   +  G Y+L     EL D++LY C   E  LR          +  L ++ PP E   +        +G+ +               N +C+S+   P   + W          V T   L D  ++  ++Y  ++        N +C   N    +  +   A +T+ V +    V L       + +  GE V+F+C +   P  I+ Y W           G  +++ +  +  V KA   F    + C +F +V   N                   S  +++ + P +    + +TV ++   V L+C+   NP  ++ W K   G+S    + N  Y                         + V++ D   Y+C+A           V +     P I  E     V  +    + C + S P P      W     E    +   RY + +     Q   V S L    +++SD+  TY C    SF  G  I++ +++ ++P+
Sbjct:   25 EPADQSVVLGQRVVLSCVVFNYSGIV----QWTKD--GLALGIGEDLRAWPRYRVLRLVDVGQYNLEISAAELSDDSLYECQATEAALRSR--------RAKLTVLIPPDEPVIEGSPEILLTAGVPY---------------NMSCVSRGAKPASVIEWQKDGLPIEGAVSTTEVLPDRKRVTTRSYLPIQPLDTDTGKNFTCVATNLAVPMGKR---ATITLNVHH-PPVVTLSIE---PRSVLEGERVTFTCQATANP-PIMGYKW---------AKGGVVIQGARESVFVTKADHSFFTEPVSCQVFNAVGSTNV------------------SILVDVHFGPILVVEPKPVTV-DVDSDVTLNCKWAGNPPLTLTWTKK--GSSMVLSNNNQLY------------------------LKSVSQADAGQYVCKAIVPRIGVGETEVTLTVNGPPIISSEPFQYAVRGE-RGEVKCYIASTPPPDKIVWAWKENVWEKEKGTLSERYTVEQSKPSAQGGAVLSTLTINNIMESDFQSTYNCTAWNSFGSGTMIISLEEMEIVPV 500          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNS-NISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCS 1702
            +P ++ ++ G+P  L C +   + +V     W KD   L  +     Y  R  + G    G Y L  + TEL D+  + C  I++  R             L ++ PP +              II      ++ +     LN TC + N  P   ++W            T+T L D GK +    +L   +S+  +   I+C+  NK    +GK  T  + +Q   + N  +        +P+  G  V F C +   P  + +Y W           G  ++  ++ +   +     F    + C +  ++      +NI+RN              +++ + P++    +++ V   G   V SC    NP  +I W K   G                           ++S+ +    + V + D   Y+C A         K V++     P+I   Q    +  +    + C + S   P P  I W ++ + L   ++ R  +       GV S L  + ++ +D+ T Y C+
Sbjct:   26 QPHDLVIVAGEPVTLPCTIIGYQGMV----LWVKDGLALGVNRDLSGYP-RYDVIGDHSKGEYHLLIERTELVDDGSFECQAIQVAGRSR--------PAQLTVLVPPDD------------PVIIGAP---VVSLRAGDSLNLTCHANNAKPAASIIWIRNGEVINGAAYTKTLLRD-GKRESTVSTLHISASNIESGQQITCRASNKA-APNGKEATVTIDIQHFPLVNLSVE------PQPVLEGNLVKFHCAAKANPP-VTHYRW---------AKGGSMITDATGDTYEVLVDHSFFTEPVSCEVTNALGS----TNISRN--------------VDVYFGPRLAAEPQSLQVDR-GSDAVFSCAWIGNPSLTIVWMKRGHGV--------------------------VLSNENTLTLKAVRQEDAGKYVCRAVVPRVGVGEKEVMLTVNGPPSISSTQTQQALYGEK-GQIKCFIRS--TPPPDRIAWSWKETVLESGTSGRYTVETVSTEEGVISTLTMRNIVPTDFQTIYNCT 473          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNS-NISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCS 1702
            +P ++ ++ G+P  L C +   + +V     W KD   L  +     Y  R  + G    G Y L  + TEL D+  + C  I++  R             L ++ PP +              II      ++ +     LN TC + N  P   ++W            T+T L D GK +    +L   +S+  +   I+C+  NK    +GK  T  + +Q   + N  +        +P+  G  V F C +   P  + +Y W           G  ++  ++ +   +     F    + C +  ++      +NI+RN              +++ + P++    +++ V   G   V SC    NP  +I W K   G                           ++S+ +    + V + D   Y+C A         K V++     P+I   Q    +  +    + C + S   P P  I W ++ + L   ++ R  +       GV S L  + ++ +D+ T Y C+
Sbjct:   26 QPHDLVIVAGEPVTLPCTIIGYQGMVL----WVKDGLALGVNRDLSGYP-RYDVIGDHSKGEYHLLIERTELVDDGSFECQAIQVAGRSR--------PAQLTVLVPPDD------------PVIIGAP---VVSLRAGDSLNLTCHANNAKPAASIIWIRNGEVINGAAYTKTLLRD-GKRESTVSTLHISASNIESGQQITCRASNKA-APNGKEATVTIDIQHFPLVNLSVE------PQPVLEGNLVKFHCAAKANPP-VTHYRW---------AKGGSMITDATGDTYEVLVDHSFFTEPVSCEVTNALGS----TNISRN--------------VDVYFGPRLAAEPQSLQVDR-GSDAVFSCAWIGNPSLTIVWMKRGHGV--------------------------VLSNENTLTLKAVRQEDAGKYVCRAVVPRVGVGEKEVMLTVNGPPSISSTQTQQALYGEK-GQIKCFIRS--TPPPDRIAWSWKETVLESGTSGRYTVETVSTEEGVISTLTMRNIVPTDFQTIYNCT 473          

Query:   47 FVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYK-GRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTA---VVTVQVLYIKNAVILRTNGNIDKP-IHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNIN-RNCNIE-LRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCSF--SYGKTIVT---KQIHLLPL 1753
             V   + +FFL      +    +PS+  ++ G+   L C +     VV    QW+ D  GL     +D+    R ++ G    G ++LH +  EL D+A+Y C        S+       +  L ++ PP +      +  +  + ++            N   N TC++    P  ++ W          V T+  LSD       +  L+  S     S+ +C++ N+       LP      VT+ V Y     +     +++ P I  G +V+F C ++  P  +  Y W      +     +Y VE   +          F  + + C +  SV   N  + +N   C I    H   +S S+N++ P  +  P   +TV +IG+     C    NP  +  W K   GT +   + N      T+ L +VT                    D  IY+C+A         K V +  +  P I  E    +    G A + CL+ES   P+P  I W ++   L   S  R  +  +   +G  S L       SD+ T + CS    YG+  V    +Q   LPL
Sbjct:   21 LVPFSICAFFLTGFGAHF--SQQPSDKVIVAGKSVTLPCVVIGYRGVV----QWTMD--GLALGAERDLPGWSRYSVVGDPSLGEHNLHIEGVELSDDAIYECQATQAALRSQ-------RARLTVLLPPGDP----MIPGSPVANVLL-----------NVPYNLTCLAPVAKPAAEITWYRDGKKLDSAVYTKELLSDGKSEGSASSLLITPSLADSGSSYTCRVRNE------ALPEGREKSVTLSVQYPPKVTL-----SVEPPTITEGGSVTFLCGAVSNPE-VTGYRWAKGGVPLAVSGDKYTVEVDHT----------FFTAPVSCEVSNSVGASNVSTAVNVLRCPISNFIH---TSFSVNLVGPRLLTEP-RPMTV-DIGDDASFFCGWTGNPTPTQFWSKK--GTGEVLSNGN------TLLLTKVT------------------REDAGIYVCKAIVPRMGSTEKEVTLTVRGPPIITSEMH-YETTLGGKARMECLIES--TPAPDRIVWAWDKQSLEDGSWGRFSVETEVTEVGAISVLVIDGAEQSDFLTEFNCSAINQYGEDSVIVSLRQQAALPL 525          

Query:   98 YVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKP-----------IHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKF-QVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTC----SFSYGKTIV 1726
            Y+L  EP++  V+ GQ  VL C +     +V    QW+KD   L       ++  R  I G+++SG Y+L      + D+A + C   E  LR          K  L ++ PP +   +                   I +      N TC + +  P   ++W         D  +     YS   L+     + +S  +++  D   G++ T   + + +       ++   N+  P           +  GE V F+C++   P  I  Y W           G  ++E +  ++   +    F    + C +   V   N                   S  +++ + P++       T +++G  V L+C    NP  ++ W K                              NM+ S     F + V + D   Y+C+A         + V +     P I  E+       D    + C + S   P P  I W ++ + L   + ER  +       GV S L    V++SD+ T Y C    SF  G  I+
Sbjct:    5 YLLLTEPTDQTVVAGQKVVLTCVVLNYSGIV----QWTKDGLALGLGQNLRIWP-RYQIVGNVESGQYNLEISNASIVDDANFECQATEAALRSQ--------KAKLTVLIPPEDPVIEGGPE---------------ILLRAGTPTNLTCRANSAKPPASIVW-------FRDGNQQAGDVYSTEVLADGKRATTVSYLLISPTDQDIGRVFTCRTSNEAIPSGKETSVKL--NVHHPPTVTLSIHPQTVQEGERVRFTCSATANPE-IKGYRW---------AKGGMIIESARDSSYETQVDYSFFTEPVSCEVHNEVGSTNV------------------STLVDVQFAPRVVVE-PKPTTTDMGSDVTLTCIWAGNPPLTLTWTKKG---------------------------SNMVLSNGNQLFLKSVKQEDAGPYVCKAIVPRIGVGEREVTLFVNGPPIIASEEVQYAARGDK-GKVECFIGS--TPPPDRIAWAWKENVLETGTLERYTVERTTSTSGVLSTLTINNVMESDFQTRYNCTAWNSFGPGTAII 469          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYK-GRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTA---VVTVQVLYIKNAVILRTNGNIDKP-IHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCS 1702
            +PS+  ++ G+   L C +     VV    QW+ D  GL     +D+    R ++ G    G ++LH +  EL D+A+Y C        S+       +  L ++ PP +      +  +  + ++            N   N TC++    P  ++ W          V T+  LSD       +  L+  S     S+ +C++ N+       LP      VT+ V Y     +     +++ P I  G +V+F C ++  P  +  Y W         + G  L    S +   ++    F  + + C +  SV   N                   S ++N+L+ P++ T    +TV +IG+     C    NP  +  W K   GT +   + N      T+ L +VT                    D  IY+C+A         K V +  +  P I  E    +    G A + CL+ES   P+P  I W ++   L   S  R  +  +   +G  S L       SD+ T + CS
Sbjct:   33 QPSDKVIVAGKSVTLPCVVIGYRGVV----QWTMD--GLALGAERDLPGWSRYSVVGDPSLGEHNLHIEGVELSDDAIYECQATQAALRSQ-------RARLTVLLPPGDP----MIPGSPVANVLL-----------NVPYNLTCLAPVAKPAAEITWYRDGKKLDSAVYTKELLSDGKSEGSASSLLITPSLADSGSSYTCRVRNE------ALPEGREKSVTLSVQYPPKVTL-----SVEPPTITEGGSVTFLCGAVSNPE-VTGYRW--------AKGGVPLA--VSGDKYTVEVDHTFFTAPVSCEVSNSVGASNV------------------STAVNVLFGPRLLTEPRPMTV-DIGDDASFFCGWTGNPTPTQFWSKK--GTGEVLSNGN------TLLLTKVT------------------REDAGIYVCKAIVPRMGSTEKEVTLTVRGPPIITSEMH-YETTLGGKARMECLIES--TPAPDRIVWAWDKQSLEDGSWGRFSVETEVTEVGAISVLVIDGAEQSDFLTEFNCS 479          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYK-GRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKP-IHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCSF--SYGKTIVT---KQIHLLPL 1753
            +PS+  ++ G+   L C +     VV    QW+ D  GL     +D+    R ++ G    G ++LH +  EL D+A+Y C   +  LR          +  L ++ PP +      +  +  + ++            N   N TC++    P  ++ W          V T+  LSD       +  L+  S     S+ +C++ N+    +G+     VT+ V Y     +     +++ P I  G +V+F C ++  P  +  Y W      +     +Y VE   +          F  + + C +  SV   N                   S ++N+L+ P++ T    +TV +IG+     C    NP  +  W K   GT +   + N      T+ L +VT                    D  IY+C+A         K V +  +  P I  E    +    G A + CL+ES   P+P  I W ++   L   S  R  +  +   +G  S L       SD+ T + CS    YG+  V    +Q   LPL
Sbjct:   25 QPSDKVIVAGKSVTLPCVVIGYRGVV----QWTMD--GLALGAERDLPGWSRYSVVGDPSLGEHNLHIEGVELSDDAIYECQATQAALRSQ--------RARLTVLLPPGDP----MIPGSPVANVLL-----------NVPYNLTCLAPVAKPAAEITWYRDGKKLDSAVYTKELLSDGKSEGSASSLLITPSLADSGSSYTCRVRNEA-LPEGR--EKSVTLSVQYPPKVTL-----SVEPPTITEGGSVTFLCGAVSNPE-VTGYRWAKGGVPLAVSGDKYTVEVDHT----------FFTAPVSCEVSNSVGASNV------------------STAVNVLFGPRLLTEPRPMTV-DIGDDASFFCGWTGNPTPTQFWSKK--GTGEVLSNGN------TLLLTKVT------------------REDAGIYVCKAIVPRMGSTEKEVTLTVRGPPIITSEMH-YETTLGGKARMECLIES--TPAPDRIVWAWDKQSLEDGSWGRFSVETEVTEVGAISVLVIDGAEQSDFLTEFNCSAINQYGEDSVIVSLRQQAALPL 493          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYK-GRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFH-VANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTA---VVTVQVLYIKNAVILRTNGNIDKP-IHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCSF--SYGKTIVT---KQIHLLPLKNKFI 1768
            +PS+  ++ G+   L C +     VV    QW+ D  GL     +D+    R ++ G    G ++LH +  EL D+A+Y C        S+       +  L ++ PP +       VAN                V  N   N TC++    P  ++ W          V T+  LSD       +  L+  S     S+ +C++ N+       LP      VT+ V Y     +     +++ P I  G +V+F C ++  P  +  Y W      +     +Y VE   +          F  + + C +  SV   N                   S ++N+L+ P++ T    +TV +IG+     C    NP  +  W K   GT +   + N      T+ L +VT                    D  IY+C+A         K V +  +  P I  E    +    G A + CL+ES   P+P  I W ++   L   S  R  +  +   +G  S L       SD+ T + CS    YG+  V    +Q   LPL    I
Sbjct:   29 QPSDKVIVAGKSVTLPCVVIGYRGVV----QWTMD--GLALGAERDLPGWSRYSVVGDPSLGEHNLHIEGVELSDDAIYECQATQAALRSQ-------RARLTVLLPPGDPMIPGSPVAN----------------VLLNVPYNLTCLAPVAKPAAEITWYRDGKKLDSAVYTKELLSDGKSEGSASSLLITPSLADSGSSYTCRVRNE------ALPEGREKSVTLSVQYPPKVTL-----SVEPPTITEGGSVTFLCGAVSNPE-VTGYRWAKGGVPLAVSGDKYTVEVDHT----------FFTAPVSCEVSNSVGASNV------------------STAVNVLFGPRLLTEPRPMTV-DIGDDASFFCGWTGNPTPTQFWSKK--GTGEVLSNGN------TLLLTKVT------------------REDAGIYVCKAIVPRMGSTEKEVTLTVRGPPIITSEMH-YETTLGGKARMECLIES--TPAPDRIVWAWDKQSLEDGSWGRFSVETEVTEVGAISVLVIDGAEQSDFLTEFNCSAINQYGEDSVIVSLRQQAALPLTLLLI 502          

Query:   17 KMTVGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW--------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNI-SCK-----IVNKKDY---LDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYH-KFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTC----SFSYGKTIV-TKQIHLLPL 1753
            KM      +A+++ +  +  L    T++    EP++  V+ GQ  VL C L     +V    QW+KD   L        +  R  + GS  +G Y+L     EL D+A Y C   E  LR          +  L ++ PP E                      +I +      N TC + N  P   ++W           T T L  +GK +     L+   +D     + +C+     I N K+    LD   P  V     L I+   +L            GE V F+C +   P  I+ Y W           G +L+E +  +         F    + C ++  V   N                   S  +N+ + P+I   +   T ++IG  V L+C    NP  ++ W K                              NM+ S S     + V + D   Y C A         + V +     P I  E     V  DG   + C + S   P P  I W ++ + L + + ER  +       GV S L    V+++D+ T Y C    SF  G  I+  ++  +LP+
Sbjct:   28 KMWAPHLVVAYLIFVTLALALPGTQTRF--SQEPADQTVVAGQRAVLPCVLLNYSGIV----QWTKDGLALGMGQGLKAWP-RYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSR--------RAKLTVLIPPEETRID---------------GGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTV----TLSIEPQTVL-----------EGERVIFTCQATANPE-ILGYRW---------AKGGFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNV------------------STLVNVHFAPRIVV-YPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKD---------------------------SNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDG-GKVECFIGS--TPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPV 527          

Query:   17 KMTVGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW--------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNI-SCK-----IVNKKDY---LDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYH-KFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTC----SFSYGKTIVT-KQIHLLPL 1753
            KM      +A+++ +  +  L    T++    EP++  V+ GQ  VL C L     +V    QW+KD   L        +  R  + GS  +G Y+L     EL D+A Y C   E  LR          +  L ++ PP E                      +I +      N TC + N  P   ++W           T T L  +GK +     L+   +D     + +C+     I N K+    LD   P  V     L I+   +L            GE V F+C +   P  I+ Y W           G +L+E +  +         F    + C ++  V   N                   S  +N+ + P+I   +   T ++IG  V L+C    NP  ++ W K                              NM+ S S     + V + D   Y C A         + V +     P I  E     V  DG   + C + S   P P  I W ++ + L + + ER  +       GV S L    V+++D+ T Y C    SF  G  I+  ++  +LP+
Sbjct:   28 KMWAPHLVVAYLIFVTLALALPGTQTRF--SQEPADQTVVAGQRAVLPCVLLNYSGIV----QWTKDGLALGMGQGLKAWP-RYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSR--------RAKLTVLIPPEETRID---------------GGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTV----TLSIEPQTVL-----------EGERVIFTCQATANPE-ILGYRW---------AKGGFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNV------------------STLVNVHFAPRIVV-YPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKD---------------------------SNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDG-GKVECFIGS--TPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPV 527          

Query:   17 KMTVGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW--------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNI-SCK-----IVNKKDY---LDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYH-KFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTC----SFSYGKTIVT-KQIHLLPL 1753
            KM      +A+++ +  +  L    T++    EP++  V+ GQ  VL C L     +V    QW+KD   L        +  R  + GS  +G Y+L     EL D+A Y C   E  LR          +  L ++ PP E                      +I +      N TC + N  P   ++W           T T L  +GK +     L+   +D     + +C+     I N K+    LD   P  V     L I+   +L            GE V F+C +   P  I+ Y W           G +L+E +  +         F    + C ++  V   N                   S  +N+ + P+I   +   T ++IG  V L+C    NP  ++ W K                              NM+ S S     + V + D   Y C A         + V +     P I  E     V  DG   + C + S   P P  I W ++ + L + + ER  +       GV S L    V+++D+ T Y C    SF  G  I+  ++  +LP+
Sbjct:   28 KMWAPHLVVAYLIFVTLALALPGTQTRF--SQEPADQTVVAGQRAVLPCVLLNYSGIV----QWTKDGLALGMGQGLKAWP-RYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSR--------RAKLTVLIPPEETRID---------------GGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTV----TLSIEPQTVL-----------EGERVIFTCQATANPE-ILGYRW---------AKGGFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNV------------------STLVNVHFAPRIVV-YPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKD---------------------------SNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDG-GKVECFIGS--TPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPV 527          

Query:   83 SNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTE---LGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTET--------GLSDNGKIQRQNYSLMRLSSDFHNS-NISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCD-SNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFG 1240
            S    Y    +P +  V+ GQP  L C   IPE      + W KD   L        Y   L + G+  SG + L     ELQD+A+Y C  I+  +R             L ++ PP +   LG                    +I +     LN TC + N  P   ++W  K E          L  +GK +    +L     D  N  +I C+  NK     GK  +  + +Q   + N  +        +P+     V+F C++   P  +  Y W                  +   +I+ +AS + + + +    F+  +  +C+ +N   + N+        S+++++ + P++ +  +++ V ++G   V SC    NP  +I W K   G
Sbjct:   17 SQGQVYSFSQQPQDQVVVSGQPVTLLC--AIPE--YDGFVLWIKDGLALGVGRDLSSYPQYLVV-GNHLSGEHHLKILRAELQDDAVYECQAIQAAIRSR--------PARLTVLVPPDDPIILG------------------GPVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKA-IPGGKETSVTIDIQHPPLVNLSVE------PQPVLEDNIVTFHCSAKANPA-VTQYRW------------------AKRGHIIKEASGELYRTTVDYTYFS--EPVSCEVTNALGSTNL--------SRTVDVYFGPRMTSEPQSLLV-DLGSDAVFSCAWIGNPSLTIVWMKRGSG 348          

Query:   41 IAFVVIML-SSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKI-------QRQ--NYSLMRLSS--DFHNSNISCKIVNKKDY--------------------LDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSF--SYGKTIVTKQIH 1741
            +A +V M+ SS +    + ++ +  EP +   ++G    L CR+   +      LQW+KD FGL  S     ++ R  + GS + G Y L      L D+A Y C +         + S      L ++ PP                     +  +I+  E++K+   C+S  G P  ++ W       L+DN +        QR+    S++RL+   + HN+N SC+  N  D                     + G LP             +V + T   I +  H+   V   C +   P   + Y WF+        N E ++    +  ++   + KFH + + C +  SV K                     S++L+I Y P  +   +++  +++G  V L+CEVDSNPQ  I W +                             + ++ +++   F V NE     Y C+A    + +I     V  K  P I  ++    +  D  A + C   S P+    ++ W F   E++  S     ++      GV+S L  +      YG Y C+    YG  +   Q+ 
Sbjct:   10 LATIVGMVRSSPYTSYQNQRFAM--EPQDQTAVVGARVTLPCRVINKQGT----LQWTKDDFGLGTSRDLSGFE-RYAMVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFA--GLTVLVPPEAPKI---------------TQGDVIYATEDRKVEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVE--HS--QVRLECRADANPS-DVRYRWFI--------NDEPIIGGQKTEMVIRNVTRKFHDAIVKCEVQNSVGKSE------------------DSETLDISYAPSFRQRPQSME-ADVGSVVSLTCEVDSNPQPEIVWIQHPS--------------------------DRVVGTSTNLTFSVSNE-TAGRYYCKANVPGYAEISADAYVYLKGSPAIGSQRTQYGLVGD-TARIECFASSVPR--ARHVSWTFNGQEISSESGHDYSILVDAVPGGVKSTLIIRDSQAYHYGKYNCTVVNDYGNDVAEIQLQ 524          

Query:   17 KMTVGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW--------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNI-SCK-----IVNKKDY---LDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYH-KFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTC----SFSYGKTIVT-KQIHLLPL 1753
            KM      +A+++ +  +  L    T++    EP++  V+ GQ  VL C L     +V    QW+KD   L        +  R  + GS  +G Y+L     EL D+A Y C   E  LR          +  L ++ PP E                      +I +      N TC + N  P   ++W           T T L  +GK +     L+   +D     + +C+     I N K+    LD   P  V     L I+   +L            GE V F+C +   P  I+ Y W           G +L+E +  +         F    + C ++  V   N                   S  +N+ + P+I   +   T ++IG  V L+C    NP  ++ W K                              NM+ S S     + V + D   Y C A         + V +     P I  E     V  DG   + C + S   P P  I W ++ + L + + ER  +       GV S L    V+++D+ T Y C    SF  G  I+  ++  +LP+
Sbjct:   28 KMWAPHLVVAYLIFVTLALALPGTQTRF--SQEPADQTVVAGQRAVLPCVLLNYSGIV----QWTKDGLALGMGQGLKAWP-RYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSR--------RAKLTVLIPPEETRID---------------GGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTV----TLSIEPQTVL-----------EGERVIFTCQATANPE-ILGYRW---------AKGGFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNV------------------STLVNVHFAPRIVV-YPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKD---------------------------SNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDG-GKVECFIGS--TPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPV 527          

Query:   17 KMTVGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW--------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNI-SCK-----IVNKKDY---LDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYH-KFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTC----SFSYGKTIVT-KQIHLLPL 1753
            KM      +A+++ +  +  L    T++    EP++  V+ G   VL C L     +V    QW+KD   L        +  R  + GS  +G Y+L     EL D+A Y C   E  LR          +  L ++ PP +                      +I +      N TC + N  P   ++W           T T L  +GK +     L+   +D     + +C+     I N K+    LD   P  V     L I+   +L            GE V F+C +   P  I+ Y W           G +L+E +  +         F    + C ++  V   N                   S  +N+ + P+I   +   T ++IG  V L+C    NP  ++ W K                              NM+ S S     + V + D   Y C A         + V +     P I  E     V  DG   + C + S   P P  I W ++ + L + + ER  +       GV S L    V+++D+ T Y C    SF  G  I+  ++  +LP+
Sbjct:   28 KMWAPHLVVAYLIFVTLALALPGTQTRF--SQEPADQTVVAGHRAVLPCVLLNYSGIV----QWTKDGLALGMGQGLKAWP-RYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSR--------RAKLTVLIPPEDTRID---------------GGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIQPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTV----TLSIEPQTVL-----------EGERVIFTCQATANPE-ILGYRW---------AKGGFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNV------------------STLVNVHFAPRIVV-YPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKD---------------------------SNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDG-GKVECFIGS--TPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPV 527          

Query:   41 IAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW--------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNI-SCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYH-KFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTC----SFSYGKTIVT-KQIHLLPL 1753
            ++ +V +L+     S  T+     EP++  V+ GQ  VL C L     +V    QW+KD   L        +  R  + GS  +G Y+L     EL D+A Y C   E  LR          +  L ++ PP +                      +I +      N TC + N  P   ++W             T L  +GK +     L+   +D     + +C+ +N+       +P+   T   L + +   + T     + +  GE V F+C +   P  I+ Y W           G +L+E +  +         F    + C +   V   N                   S  +N+ + P+I       T ++IG  V L+C    NP  ++ W K                              NM+ S S     + V + D   Y C A         + V +     P I  E     V  DG   + C + S   P P  I W ++ + L + + ER  +       GV S L    V+++D+ T Y C    SF  G  I+  ++  +LP+
Sbjct:    2 LSLLVWILTLSDTFSQGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIV----QWTKDGLALGMGQGLKAWP-RYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSR--------RAKLTVLIPPEDTRID---------------GGPVILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSMNE------AIPSGKETSIELDVHHPPTV-TLSIEPQTVQEGERVVFTCQATANPE-ILGYRW---------AKGGFLIEDAHESRYETNVDYSFFTEPVSCEVHNKVGSTNV------------------STLVNVHFAPRIVVD-PKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKD---------------------------SNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQYAVRGDG-GKVECFIGS--TPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPV 495          

Query:   53 VIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLE-IPENVVKIKLQWSKD---MFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTE--LQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQN-------YSLMRLSSDF--HNSNISCKIVNKK--------DYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDN-----CDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNI--GEWVVLSCE-VDSNPQASIRW 1222
             I+L  F  +  S+++ L + PS +  I G+    +C  E  PE +V    QW  +   + G     I   ++GR +    I+    +LH K T   L D+  Y C +   L   E    +  K  L II PP  + F  +  N            SII V EN  LN TC+  N  P P+++W +  +    D  +    +       Y+ + + SD   H   I+C+   K+          LD   P +  TV++L  +N   LR+  N+         ++ S      P  + +Y     + N   Q+   L  RS      IK          +   F + Q DN     C +N +R  N   + KA+    L + YPP      E    SNI  G    + C+ + SNP + I W
Sbjct:    5 AILLWLFGSIHISSQFFL-ESPSNLSTIAGESITFRCSAEKSPEPIVYS--QWKSNTGSLLGYHQEGILPGHQGRFSY---IKQNAEELHLKITHVNLDDDGEYECQM---LHPEE--GPIRAKSFLNIIVPPQLVYFSNYQPN------------SIIAVKENTPLNITCVVPNVKPEPEVLWYMDGKVMSRDVKQASTPHLNKTFTVYTSLVVQSDRNDHGKVITCEAFQKETDIRITTNTTLDVLFPPSDPTVEIL--RNPSALRSGDNV--------TIACSVTGGNPPPDVFWY-----HENKRLQSHSTLDTRSKE----IK----------NIYSFIASQNDNMAEYECRANNSRTGNP--KRKAM---KLEVNYPP---ASVELFGESNIRYGSSANIQCKSLPSNPASQITW 365          

Query:  116 PSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGF---QFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------------------TVKTETGLSDNGK---IQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHN---GEAVSFSCNSIFTPGIIIYYSWFVEYN-NVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRN---------CNIELRHKAVSSKS--LNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSK---NTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFS--YGKTIVTKQIHLLPLKNKFIIFI 1777
            P    V++     L+CR+    +   +K+QW KD FG EN T++D + GR  +PG  ++G YDL   + + QD+  Y C +   +   E  +S+    +L +I PP ++     QF   N S +  I Q     IW   N+ L  +C  +   P  +L+W                     TV T++   D+      + +++  +RL  D +   + C I N++ ++      A++ + VL++ +   ++ +    +P  +    E +  +C++   P  +I Y+W ++YN   +        +RS    I ++      F R  C + + +    C SN              N   RH A  S    L + Y P I         + +G+ V L C  DSNP A I WYK+ F + +   N   +          ++  + +  +  S  YH F + +  +L ++IC A    F  + K V V +   P I   Q  I  ++     + C + S P P    I W+   +   I +  +  +  + +L GV S L+  KV   DYGTY CS S  YG+  V+  I L+P     +IFI
Sbjct:   36 PVSTSVLINSTARLRCRVTFNNSNTPVKVQWQKDGFGYENETLRDHFNGRYQMPGPRETGTYDLVIHSVDKQDDGEYACQVNAAIHILETTKSI----NLTVIVPPDKIKLKSSQFDFQNNSTNNEIIQN----IWGHLNEFLILSCEIQYSRPATELVWKLGEFALREGKSGDIDGQEVGTVTTKSEFMDSFDQFYYKSESHLRLRLRKDHNGEILKCTIANEQSFMHKTPKPAIMKLNVLFVLD---VKMDVIPHRPFFHFTEHEMIQINCSASTNPANVI-YNW-IKYNPTTKTTTIIKYFDRSGVLKIKVRRDLNNMFIR--CQVLSVLAGKECYSNFQAESIIYDNSYLVNCSERHTANGSSQIILRVQYSPIILDSILETKAAFLGDVVTLDCRADSNPPAKITWYKSKFSSKEIMANPDLVGARNLQKDTQMSSYSSMTLLSISDKYH-FTITDADNLGLFICIALTDGFPPVQKTVFVGQGATPQIVNNQKIIIAKSGLSVRISCHIISIPLPDKGKIIWFKNLNTKPIEAKSKNQIYEEERLAGVVSYLYIHKVTYEDYGTYNCSVSNPYGR--VSSTIELIPPVETPMIFI 618          

Query:   26 VGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKII-EPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWT----------VKTETGLSDNGKIQRQNYSLMRLSSD--FHNSNISCKIVNKKDYLDGKLP-TAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWY---KTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGV-ESKLFFKKVIDSDYGTYTCSFS--YG---KTIVTKQIHLLPLKNKFIIFIS 1780
            VG + ++F+V+M+          ++ +  EP +   I+G    L CR+E   N V   LQW+KD FGL        Y  R  + GS + G + L  K   L+D+  Y C +         + S   + ++ +  E P  L                  R + I   E Q +   C+S  G P  ++ W           VK+   L  +G+ + +  S++RL+     HN  I+C+  N  D    + P  A+V ++V Y+    +  T+G+  + I  G  +   C+    P   IY  W++  N V    G+Y  E      I+   + K H + + C +  SV K   ++                  +L + YPP  +T  +N+  ++IG  VVLSC+VD  PQ  IRW        G      ++  Y +  T                               YIC+     + +I     +  K  PTI   +    +E + +  + C   S PK  P +I+WYFE  E+++I       + +    GV +S L  +      YG Y CS +  YG     I+ K +  LPL   +II I 
Sbjct:   42 VGIQILSFLVLMVGCHGY--QEQRFAM--EPQDQSAIVGSRVTLPCRVE---NKVG-ALQWTKDDFGLGTHRNLSGYD-RYAMIGSDEEGDFSLDIKDLTLEDDGQYQCQVSSGHNGEPAIRSRYAQLTVLVAPEAPRIL------------------RGAFIDATEGQPVEIECVSSGGKPASEITWLDGNQSVIKKHVKSTVELLPDGQ-RYKTRSVLRLTPAKIHHNQTITCQAQNTAD----RAPRMAIVHIEVKYVPKVNVSMTSGH--RRIPEGSELRVRCDVDANPPAQIY-RWYINNNPVV---GDYAEEM-----IIFNVTRKHHKAIVRCEVSNSVGKGEGNT------------------TLEVTYPPTFRTRPQNVE-TDIGSSVVLSCDVDGQPQPEIRWLFHEPGRIGVKGKAPNLKVYVKPETAGR----------------------------YICKVIEEGYPEIESEATIFIKSAPTILSNRTQFGMEGESV-RIECAARSVPK--PDDIRWYFEGREISVIQDPDYATLEESLPDGVIKSSLVIRASQSKHYGQYNCSVTNEYGNANAAIMLKPLKTLPL---YIILIG 553          

Query:   26 VGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKII-EPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWT----------VKTETGLSDNGKIQRQNYSLMRLSSD--FHNSNISCKIVNKKDYLDGKLP-TAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGV-ESKLFFKKVIDSDYGTYTCSFS--YG---KTIVTKQIHLLPLKNKFIIFIS 1780
            VG + ++F+V+M+          ++ +  EP +   I+G    L CR+E   N V   LQW+KD FGL        Y  R  + GS + G + L  K   L+D+  Y C +         + S   + ++ +  E P  L                  R + I   E Q +   C+S  G P  ++ W           VK+   L  +G+ + +  S++RL+     HN  I+C+  N  D    + P  A+V ++V Y+    +  T+G+  + I  G  +   C+    P   IY  W++  N V    G+Y  E      I+   + K H + + C +  SV K   ++                  +L + YPP  +T  +N+  ++IG  VVLSC+VD  PQ  IRW                         +E   I  +       K  V  E     YIC+     + +I     +  K  PTI   +    +E + +  + C   S PK  P +I+WYFE  E+++I       + +    GV +S L  +      YG Y CS +  YG     I+ K +  LPL   +II I 
Sbjct:   42 VGIQILSFLVLMVGCHGY--QEQRFAM--EPQDQSAIVGSRVTLPCRVE---NKVG-ALQWTKDDFGLGTHRNLSGYD-RYAMIGSDEEGDFSLDIKDLTLEDDGQYQCQVSSGHNGEPAIRSRYAQLTVLVAPEAPRIL------------------RGAFIDATEGQPVEIECVSSGGKPASEITWLDGNQSVIKKHVKSTVELLPDGQ-RYKTRSVLRLTPAKIHHNQTITCQAQNTAD----RAPRMAIVHIEVKYVPKVNVSMTSGH--RRIPEGSELRVRCDVDANPPAQIY-RWYINNNPVV---GDYAEEM-----IIFNVTRKHHKAIVRCEVSNSVGKGEGNT------------------TLEVTYPPTFRTRPQNVE-TDIGSSVVLSCDVDGQPQPEIRWL-----------------------FHEPGRIGQVKGKAPNLKVYVKPE-TAGRYICKVIEEGYPEIESEATIFIKSAPTILSNRTQFGMEGESV-RIECAARSVPK--PDDIRWYFEGREISVIQDPDYATLEESLPDGVIKSSLVIRASQSKHYGQYNCSVTNEYGNANAAIMLKPLKTLPL---YIILIG 554          

Query:   26 VGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWT----------VKTETGLSDNGKIQRQNYSLMRLSSD--FHNSNISCKIVNKKDYLDGKLP-TAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGV-ESKLFFKKVIDSDYGTYTCSFS--YG---KTIVTKQIHLLPLKNKFIIFIS 1780
            VG + ++F+V+M+          ++ +  EP +   I+G    L CR+E   N V   LQW+KD FGL        Y  R  + GS + G + L  K   L+D+  Y C +         + S                  Q  V  A  +  I   R + I   E Q +   C+S  G P  ++ W           VK+   L  +G+ + +  S++RL+     HN  I+C+  N  D    + P  A+V ++V Y+    +  T+G+  + I  G  +   C+    P   IY  W++  N V    G+Y  E      I+   + K H + + C +  SV K   ++                  +L + YPP  +T  +N+  ++IG  VVLSC+VD  PQ  IRW                         +E   I  +       K  V  E     YIC+     + +I     +  K  PTI   +    +E + +  + C   S PK  P +I+WYFE  E+++I       + +    GV +S L  +      YG Y CS +  YG     I+ K +  LPL   +II I 
Sbjct:   42 VGIQILSFLVLMVGCHGY--QEQRFAM--EPQDQSAIVGSRVTLPCRVE---NKVG-ALQWTKDDFGLGTHRNLSGYD-RYAMIGSDEEGDFSLDIKDLTLEDDGQYQCQVSSGHNGEPAIRSRYA---------------QLTVLVAPEAPRIL--RGAFIDATEGQPVEIECVSSGGKPASEITWLDGNQSVIKKHVKSTVELLPDGQ-RYKTRSVLRLTPAKIHHNQTITCQAQNTAD----RAPRMAIVHIEVKYVPKVNVSMTSGH--RRIPEGSELRVRCDVDANPPAQIY-RWYINNNPVV---GDYAEEM-----IIFNVTRKHHKAIVRCEVSNSVGKGEGNT------------------TLEVTYPPTFRTRPQNVE-TDIGSSVVLSCDVDGQPQPEIRWL-----------------------FHEPGRIGQVKGKAPNLKVYVKPE-TAGRYICKVIEEGYPEIESEATIFIKSAPTILSNRTQFGMEGESV-RIECAARSVPK--PDDIRWYFEGREISVIQDPDYATLEESLPDGVIKSSLVIRASQSKHYGQYNCSVTNEYGNANAAIMLKPLKTLPL---YIILIG 554          

Query:   23 TVGKRKIAFV-----VIMLSSFFLLS----NSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKII-EPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQ------RQNY---SLMRL--SSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQ-VVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTI-------KVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSEL-AIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFI 1777
            T+ +RK+  +     + +LS+ F +        ++ +  EP +   I+G    L CR+E   N +   LQW+KD FGL        Y+ R ++ GS + G Y L  +   L+D+ LY C +   L     + S     ++ I  +PP  L   F                  I   E + ++  C+S+ G P  ++ W    +  + DN + +       Q Y   S++RL  SS  H  +I+C+  N  D        A V ++V Y     I  + G + +    G  V   C++   P   I Y W++   N +   G+Y  E      +VI     F+ SR H       +  N               K+ ++ +LN+ YPP  +   +NI  S +G  V L C+VD +P+  IRW                +++   I +                KF  VVNE     YIC+A    +  I    ++  K  P I        +E  T++VE     S +C+      P P +I+WYFE  E+ AI+  +   L+        +S L  +      YG Y CS +         I L PLK   ++ I
Sbjct:   21 TLTRRKLGCIGQDVTIWILSALFFVGCHGYQEQRFAM--EPQDQSAIVGSRVTLPCRVE---NKIG-SLQWTKDDFGLGTHRNLSGYE-RYSMIGSDEEGDYSLDIRDVSLEDDGLYQCQVSSGLNGEPPIRSRYAHLTVLIAPQPPKILQGAF------------------IDATEGEPVDIECVSEGGKPAAEITWVDGNQVVIKDNVRSRIDELPDGQRYKTSSVLRLIPSSSHHEQHITCQAQNTADR---AYRMATVLIEVKYAPKINITMSTGVVSE----GGEVRVRCSADANPPAQI-YRWYL---NNKLLVGDYNEE------LVI-----FNVSRKHNNAVVKCEVSNAAG------------KSEATITLNVTYPPSFRFRPQNIE-STVGSNVTLICDVDGHPKPKIRW---------------LFHEPGKIGVKGKAA-----------KFSVVVNENTAGRYICKATVDGYPDIESEAIIFIKGPPKILSNRTQSGIEGETVRVE----CSSLCV------PKPDDIRWYFEGREISAILDPDYATLLETLPDGITKSSLVIRSSQSKHYGVYNCSVTNEYGNANAAISLKPLKTLPLVII 539          

Query:  101 VLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTET--------GLSDNGKIQRQNYSLMRLSSDFHNSN-ISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCSF--SYG---KTIVTKQIHLLPLK-------NKFIIFI 1777
            +   +P ++ V+ GQP  L C +     VV     W KD   L        Y  R T+ G   SG + L  +  EL D+A++ C  I+  +R             L ++ PP +      V +             I+ +     LN TC + N  P   ++W    E          L  +G+ +    +L    S+      I C+  NK    +GK  +  + +Q L + N  +        +P+  G  V F C++   P  +  Y W           G  +++  S +   +     F    + C +   +      +NI+RN              +++ + P++    +++ V ++G   V +C    NP  +I W K   G                     V   EN+++       + V + D   Y+C A         K V +     PTI   Q T +  +     + C + S   P P  I W ++ + L   ++ R  +       GV S L    ++ +D+ T Y C+   S+G   + I  K+   LP+          F+ FI
Sbjct:    1 MFSQQPQDLVVVAGQPVTLPCSIPGYHGVV----LWIKDGLALGVGRDLSGYP-RYTVVGDHSSGEHHLRIQRVELMDDAVFECQAIQAAMRSR--------PARLTVLVPPED-----PVIDGG----------PIVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISPSNIETGQKIICRASNKA-IPNGKETSVTIDIQHLPLVNLSVE------PQPVLEGNLVKFHCSAKANP-PVTQYKW---------AKGGTVIKEVSGDTYEVIVDHSFFTEAVSCEVTNPLGS----TNISRN--------------VDVYFGPRMAAEPQSLQV-DLGSDAVFNCAWTGNPSLTIVWMKRGSGV--------------------VLSNENILT------LKAVRQEDAGKYVCRAVVPRVGAGEKEVSLTVNGPPTISSTQ-THQAPHGEKGQIKCFIRS--TPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQESLPVAVIIGVAVGAFVAFI 489          

Query:  101 VLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTET--------GLSDNGKIQRQNYSLMRLSSDFHNSN-ISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCSF--SYG---KTIVTKQIHLLPLK-------NKFIIFI 1777
            +   +P ++ V+ GQP  L C +     VV     W KD   L        Y  R T+ G   SG + L  +  EL D+A++ C  I+  +R             L ++ PP +      V +             I+ +     LN TC + N  P   ++W    E          L  +G+ +    +L    S+      I C+  NK    +GK  +  + +Q L + N  +        +P+  G  V F C++   P  +  Y W           G  +++  S +   +     F    + C +   +      +NI+RN              +++ + P++    +++ V ++G   V +C    NP  +I W K   G                     V   EN+++       + V + D   Y+C A         K V +     PTI   Q T +  +     + C + S   P P  I W ++ + L   ++ R  +       GV S L    ++ +D+ T Y C+   S+G   + I  K+   LP+          F+ FI
Sbjct:    1 MFSQQPQDLVVVAGQPVTLPCSIPGYHGVV----LWIKDGLALGVGRDLSGYP-RYTVVGDHSSGEHHLRIQRVELMDDAVFECQAIQAAMRSR--------PARLTVLVPPED-----PVIDGG----------PIVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISPSNIETGQKIICRASNKA-IPNGKETSVTIDIQHLPLVNLSVE------PQPVLEGNLVKFHCSAKANPP-VTQYKW---------AKGGTVIKEVSGDTYEVIVDHSFFTEAVSCEVTNPLGS----TNISRN--------------VDVYFGPRMAAEPQSLQV-DLGSDAVFNCAWTGNPSLTIVWMKRGSGV--------------------VLSNENILT------LKAVRQEDAGKYVCRAVVPRVGAGEKEVSLTVNGPPTISSTQ-THQAPHGEKGQIKCFIRS--TPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQESLPVAVIIGVAVGAFVAFI 489          

Query:   53 VIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVV---KIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCS 1702
            +I L   F +S +   V   +P +V V+ GQP  L C +     +V    + L  ++D+ G            R  + G    G Y L  + TEL D+  + C  I+  +R             L ++ PP +              II      I+ +     LN TC + N  P   ++W          + ++T L D  +    +   +  S+      I+C+  NK    +GK  T  + +Q L + N  +        +PI  G  V F C++   P  + +Y W           G  ++     ++        F    + C +  ++      +NI+RN              +++ + P++    +++ V ++G   V +C    NP  +I W K   G                           ++S+ +    + V + D   Y+C A         K V +     PTI   Q    +  +    + C + S   P P  I W ++ + L   ++ R  +       GV S L    ++ +D+ T Y C+
Sbjct:   15 LIPLCLCFCVSGACA-VFVQQPHDVVVVAGQPVTLPCSITGFHGMVLWDGLALGVNRDLSGYP----------RYDVIGDHSKGEYHLLIQRTELGDDGSFECQGIQAGIRSR--------PARLTVLVPPDD------------PVIIGAP---IVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGQRESTVSTLYISASNIESGQRITCRASNKA-APNGKEATVTIDIQHLPLVNLSVE------PQPILEGNLVKFHCSAKANP-PVTHYRW---------AKGGAVIRDVLGDSYEAVVDHSFFTEPVSCEVTNALGS----TNISRN--------------VDVYFGPRLAAEPQSLQV-DLGSDAVFNCAWTGNPSLTIVWMKRGHGV--------------------------VLSNENTLTLKAVKQEDAGKYVCRAVVPRVGVGEKEVTLTVNGPPTISSTQTQQALYGEK-GQIKCFIRS--TPPPDRIAWSWKETVLESGTSGRYTVETVSTEEGVISTLTMSNIVPADFQTIYNCT 479          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYK-GRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------TVKTETGLSDNGKIQRQNY-SLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQ-----VLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLM----GVESKLFFKKVIDSDY-GTYTCS----FSYGKTIVT-KQIHLLPL 1753
            EP++  V+LGQ  VL C +     +V    QW+KD  GL     +D+    R  +   +  G Y+L   + EL D++LY C   E  LR          +  L ++ PP E   +        +G+                 N +C+S+   P   + W            T   L D  ++  +++  ++ + +D    N +C   N    + GK  T  + V      VL I+   +L            GE V+F+C +   P  I+ Y W           G  +++ +  +  + KA   F    + C +F +V   N                   S  +++ + P +    + +TV +  + V L+C+   NP  ++ W K   G+S    + N  Y                         + V++ D   Y+C+A           V +     P I  E     V  +    + C + S P P      W     E    +   RY + + +       V S L    V++SD+  TY C+    F  G  I+T ++  ++P+
Sbjct:    7 EPADQSVVLGQRVVLSCVVFNYSGIV----QWTKD--GLALGIGEDLRAWPRYRVLRMVDIGQYNLEISSAELSDDSLYECQATEAALRSR--------RAKLTVLIPPDEPVIEGSPEILLTAGV---------------PHNLSCVSRGAKPPAAIEWQKDGLPIEGAFSTTEVLPDRKRVTTRSFLPVLPVDTDT-GKNFTCMATNPAVPM-GKRTTITLNVHHPPVVVLSIEPRSVL-----------EGERVTFTCQATANP-PIMGYKW---------AKGGVVIQGARESVFITKADHSFFTEPVSCQVFNAVGSTNV------------------SILVDVHFGPILVVEPKPVTVDSDSD-VTLNCKWAGNPPLTLTWTKK--GSSMVLSNNNQLY------------------------LKSVSQADAGQYVCKAIVPRIGVGETEVTLTVNGPPIISSEPVQYAVRGE-RGEVKCYIASTPPPDKIVWAWKENVWEKEKGTLPERYTVEQSKPSSDGGAVLSTLTINNVMESDFQSTYNCTAWNGFGPGTMIITLEETEVVPV 482          

Query:  101 VLKDE----PSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIE--LTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQ-RQNYS--LMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASP-----KFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSL----NILY---PPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYK 1228
            +L+DE    PS+V V  G+P V++C  + P    +  + W KD   +      D    R+TI G        L    T   D   Y C     +  R+SEI E       L ++E P+ L                 +R S   V  +Q + F C ++ G P+P + W  + E G    G+ + R +++  L RLSS    S  +C   N     +    TA +TV V  +     +R    +   +  G  V+F C +  +P   I++                  +R  S N++  + P     +F  S+   +  T +++ +      +  NI     +V +K+L    +I+    PP ++    N TV+  G  VVL C+    P  +I W K
Sbjct:  264 ILRDEFRQNPSDVMVAAGEPAVMEC--QPPRGHPEPTISWKKDGVNV------DDRDERITIRGG------KLMITNTRKSDAGKYVCVGTNMMGERESEIAE-------LTVLERPSFL-----------------RRPSSQSVLVDQSVEFRCEAQ-GDPVPTVRW--RKEDGELPKGRFEIRDDHTLKLKRLSSADAGS-YTCLAENMMGKTEA---TATLTVHVPPV---FAVRPRNQV---VGVGRTVTFQCEATGSPQPAIFW------------------QREGSQNLLFSSQPPQPSSRFSVSQTGDLTITGIERGDAGYYSCQALNIA---GSVITKALLEVTDIISDRPPPVVRQGPTNQTVAVDGT-VVLGCQATGTPTPTILWRK 587          

Query:  968 ASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKV-ENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFS 1708
             SP  H +    +    +Q+        +  N   R       ++N+ YPP+I TP +N TV   GE + L+C V  NP  S+ W K   G S      N    T       V    N++S  +  K                       +  YV+V  K +P+I        V E  G   L C+ + +P P    + W   + +  ++S    Y              +   V  S+ GTYTC+ +
Sbjct:   42 GSPVAHGTGSAILSLLKIQRHQAGVYQCQATNDVKRGAITQDFTINVQYPPEI-TPIQNTTV-RAGETITLTCAVAGNPTPSVSWSKAGSGQSTGGNVFNEAGATKAETGQYVCTAVNIVSGNTQTK----------------------TVSTYVIV--KYKPSIIANSPYQTVNETTGSLKLSCISDGYPAPM---VTW---SRDGVVVSPTSVY--------------YSDSVTRSEAGTYTCTAT 243          

Query:   41 IAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIV--------ESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNS-NISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCS 1702
            I +V+++L   ++  +    +   +P ++ V+ GQP  L C +     +V     W KD   L        Y  R T+ G   SG + L  +  EL D+A++ C  ++  +R             + +IG G +  +     L    H  NA  +        SIIW+            +NG  +   M++  +   L  +G+ +    +L    S+      I C+  NK    +GK  +  + +Q L + N  +        + +  G  V F C++   P + + Y W           G  +++  S +   +     F    + C +  S+      +N++RN              +++ + P++    +++ V ++G   V +C    NP  +I W K   G                     V   EN+++       + V + D   Y+C A         K V +     PTI   Q    +  +    + C + S   P P  I W ++ + L   ++ R  +       GV S L    ++ +D+ T Y C+
Sbjct:    2 IPWVLLIL---WISGHEVSAMFSQQPQDLVVVAGQPVTLPCSIPGYHGIVL----WIKDGLALGVGRDLSGYP-RYTVIGDHGSGEHHLRIQRVELMDDAVFECQAVQAAMRSRPARLTVLVPPDDPVIGGGPVVSLRAGDPLNLTCHADNAKPAA-------SIIWM------------RNGEVLNGAMYSKVSIEALVRDGRRESTVSTLYLSPSNIETGQQIICRASNKA-VPNGKEASVTIDIQHLPLVNLSVE------PQAVLEGSLVRFQCSAKANPPVTL-YRW---------AKGGSIIKEVSGDTYEVIVDHSFFTEPVSCEVTNSLGS----TNVSRN--------------VDVYFGPRMAAEPQSLQV-DLGSDAVFNCAWTGNPSLTIVWMKRGSGV--------------------VLSNENLLT------LKSVRQEDAGKYVCRAVVPRVGAGEKEVSLTVNGPPTISSTQTQQALHGEK-GQIKCFIRS--TPPPDRIAWSWKETVLESGTSGRYTVETVNTEEGVISTLTMSNIVPADFQTIYNCT 474          

Query:   41 IAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTE--LGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTET--------GLSDNGKIQRQNYSLMRLSSDFHNS-NISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCS 1702
            I +V+++L   ++  +    +   +P ++ V+ GQP  L C +     +V     W KD   L        Y  R T+ G   SG + L  +  EL D+A++ C  ++  +R             L ++ PP +  +G                    ++ +     LN TC + N  P   ++W    E          L  +G+ +    +L    S+      I C+  NK    +GK  +  + +Q L + N  +        + +  G  V F C++   P + +Y  W           G  +++  S +   +     F    + C +  S+      +N++RN              +++ + P++    +++ V ++G   V +C    NP  +I W K   G                     V   EN+++       + V + D   Y+C A         K V +     PTI   Q    +  +    + C + S   P P  I W ++ + L   ++ R  +       GV S L    ++ +D+ T Y C+
Sbjct:   72 IPWVLLIL---WISGHEVSAMFSQQPQDLVVVAGQPVTLPCSIPGYHGIV----LWIKDGLALGVGRDLSGYP-RYTVIGDHGSGEHHLRIQRVELMDDAVFECQAVQAAMRSR--------PARLTVLVPPDDPVIGG-----------------GPVVSLRAGDPLNLTCHADNAKPAASIIWMRNGEVLNGAMYSKALVRDGRRESTVSTLYLSPSNIETGQQIICRASNKA-VPNGKEASVTIDIQHLPLVNLSVE------PQAVLEGSLVRFQCSAKANPPVTLYR-W---------AKGGSIIKEVSGDTYEVIVDHSFFTEPVSCEVTNSLG----STNVSRN--------------VDVYFGPRMAAEPQSLQV-DLGSDAVFNCAWTGNPSLTIVWMKRGSGV--------------------VLSNENLLT------LKSVRQEDAGKYVCRAVVPRVGAGEKEVSLTVNGPPTISSTQTQQALHGEK-GQIKCFIRS--TPPPDRIAWSWKETVLESGTSGRYTVETVNTEEGVISTLTMSNIVPADFQTIYNCT 540          

Query:  101 VLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTET--------GLSDNGKIQRQNYSLMRLSSDFHNS-NISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCS 1702
            +   +P ++ V+ GQP  L C +     +V     W KD   L        Y  R T+ G   SG + L  +  EL D+A++ C  ++  +R             L ++ PP +                      ++ +     LN TC + N  P   ++W    E          L  +G+ +    +L    S+      I C+  NK    +GK  +  + +Q L + N  +        + +  G  V F C++   P + + Y W           G  +++  S +   +     F    + C +  S+      +N++RN              +++ + P++    +++ V ++G   V +C    NP  +I W K   G                     V   EN+++       + V + D   Y+C A         K V +     PTI   Q    +  +    + C + S   P P  I W ++ + L   ++ R  +       GV S L    ++ +D+ T Y C+
Sbjct:   47 MFSQQPQDLVVVAGQPVTLPCSIPGYHGIVL----WIKDGLALGVGRDLSGYP-RYTVIGDHGSGEHHLRIQRVELMDDAVFECQAVQAAMRSR--------PARLTVLVPPDDPVI---------------GGGPVVSLRAGDPLNLTCHADNAKPAASIIWMRNGEVLNGAMYSKALVRDGRRESTVSTLYLSPSNIETGQQIICRASNKA-VPNGKEASVTIDIQHLPLVNLSVE------PQAVLEGSLVRFQCSAKANPPVTL-YRW---------AKGGSIIKEVSGDTYEVIVDHSFFTEPVSCEVTNSLGS----TNVSRN--------------VDVYFGPRMAAEPQSLQV-DLGSDAVFNCAWTGNPSLTIVWMKRGSGV--------------------VLSNENLLT------LKSVRQEDAGKYVCRAVVPRVGAGEKEVSLTVNGPPTISSTQTQQALHGEK-GQIKCFIRS--TPPPDRIAWSWKETVLESGTSGRYTVETVNTEEGVISTLTMSNIVPADFQTIYNCT 498          

Query:  101 VLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCH-IELTLRDSEIVESLIGKGSLKIIEPPTE--LGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTET--------GLSDNGKIQRQNYSLMRLSSDFHNS-NISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGT-YTCS 1702
            +   +P ++ V+ GQP  L C +     +V     W KD   L        Y  R T+ G   SG + L  +  EL D+A++ C  ++  +R             L ++ PP +  +G                    ++ +     LN TC + N  P   ++W    E          L  +G+ +    +L    S+      I C+  NK    +GK  +  + +Q L + N  +        + +  G  V F C++   P + + Y W           G  +++  S +   +     F    + C +  S+      +N++RN              +++ + P++    +++ V ++G   V +C    NP  +I W K   G                     V   EN+++       + V + D   Y+C A         K V +     PTI   Q    +  +    + C + S   P P  I W ++ + L   ++ R  +       GV S L    ++ +D+ T Y C+
Sbjct:   15 MFSQQPQDLVVVAGQPVTLPCSIPGYHGIV----LWIKDGLALGVGRDLSGYP-RYTVIGDHGSGEHHLRIQRVELMDDAVFECQAVQAAMRSR--------PARLTVLVPPDDPVIGG-----------------GPVVSLRAGDPLNLTCHADNAKPAASIIWMRNGEVLNGAMYSKALVRDGRRESTVSTLYLSPSNIETGQQIICRASNKA-VPNGKEASVTIDIQHLPLVNLSVE------PQAVLEGSLVRFQCSAKANPPVTL-YRW---------AKGGSIIKEVSGDTYEVIVDHSFFTEPVSCEVTNSLGS----TNVSRN--------------VDVYFGPRMAAEPQSLQV-DLGSDAVFNCAWTGNPSLTIVWMKRGSGV--------------------VLSNENLLT------LKSVRQEDAGKYVCRAVVPRVGAGEKEVSLTVNGPPTISSTQTQQALHGEK-GQIKCFIRS--TPPPDRIAWSWKETVLESGTSGRYTVETVNTEEGVISTLTMSNIVPADFQTIYNCT 466          

Query:  113 EPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYK-GRLTIPGSIQSGYYDLHFKTTELQDEALYGCHI-ELTLRDSEIVESLIGKGSLKIIEPPTEL---GFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMW---------TVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKF-QVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLM----GVESKLFFKKVIDSDY-GTYTC----SFSYGKTIVT 1729
            EP++  V+ GQ  +L C +     +V    QW+KD  GL     +D+    R  +    +SG Y+L   + +L D+A+Y C   +  LR          +  L ++ PP +    G    + NA                   +  N +C+S+   P   + W          V     L+D  ++  Q++  +         N SC   N        +P+   T   L + +  ++ T     + +  G+ V+F+C +   P  I+ Y W           G  +++ +  +    KA   F    + C++F +V K N       +  ++++   +      +L  P+ KT        ++   V L+C+   NP  ++ W+K                              NM+ S S   + Q V++ D   Y+C+A           V +     P I  +     V  +    + C + S P P      W     E    + + RY + + +L     GV S L    V++SD+  TY C    SF  G  I+T
Sbjct:   21 EPADQSVVRGQRVILSCVVFNYSGIV----QWTKD--GLALGIGEDLRAWPRYRVLRVQESGQYNLEILSADLSDDAVYECQAPDAALRSR--------RAKLTVLIPPDDPVIDGGPEVLLNA------------------GESYNLSCVSRGAKPPSTIEWLKDGLPVEGAVSITEVLADRKRVTTQSHLPIHPVDTDTGRNYSCVTSNL------AVPSGKSTTVTLNVHHPPVV-TLSIEPRSVLEGDRVTFTCQAHANP-PIMGYRW---------AKGGVVLQGARESVFTTKADHSFFTEPVSCLVFNAVGKTNV------SILVDVQFGPI------LLVEPQPKT-------VDVNSDVTLNCKWAGNPPLTLTWFKKG---------------------------SNMVLSNSNQLYLQSVSQADAGQYVCKAIVPRIGVGETEVTLTVNGPPIISSDPVQYAVRGE-RGEVKCYIASTPPPDKIVWAWKENVWEKERGTLQERYTVEQSKLSAEGGGVLSTLTINNVMESDFLSTYNCTAWNSFGPGTMIIT 487          

Query:   20 MTVGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNESNRSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM 2668
            MTVGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITV+NIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISIGALGVLVLLIIAVAIICACKKGTSKKRKCKKTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNESNRSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM
Sbjct:    1 MTVGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVTNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISIGALGVLVLLIIAVAIICACKKGTSKKRKCKKTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNESNRSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM 883          

Query:   20 MTVGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNESNRSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM 2668
            MTVGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITV+NIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISIGALGVLVLLIIAVAIICACKKGTSKKRKCKKTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNE  RSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM
Sbjct:    1 MTVGKRKIAFVVIMLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVTNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISIGALGVLVLLIIAVAIICACKKGTSKKRKCKKTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNE--RSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM 881          

Query:   59 MLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNESNRSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM 2668
            MLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITV+NIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISIGALGVLVLLIIAVAIICACKKGTSKKRKCKKTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNESNRSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM
Sbjct:    1 MLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVTNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISIGALGVLVLLIIAVAIICACKKGTSKKRKCKKTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNESNRSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM 870          

Query:   59 MLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVSNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNESNRSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM 2668
            MLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITV+NIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISIGALGVLVLLIIAVAIICACKKGTSKKRKCKKTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNE  RSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM
Sbjct:    1 MLSSFFLLSNSTKYVLKDEPSEVKVILGQPTVLKCRLEIPENVVKIKLQWSKDMFGLENSTIQDVYKGRLTIPGSIQSGYYDLHFKTTELQDEALYGCHIELTLRDSEIVESLIGKGSLKIIEPPTELGFQFHVANASYSGIIWQKRDSIIWVPENQKLNFTCISKNGSPMPQLMWTVKTETGLSDNGKIQRQNYSLMRLSSDFHNSNISCKIVNKKDYLDGKLPTAVVTVQVLYIKNAVILRTNGNIDKPIHNGEAVSFSCNSIFTPGIIIYYSWFVEYNNVEKQNGEYLVERSSSNNIVIKASPKFHFSRLHCMLFTSVQKDNCDSNINRNCNIELRHKAVSSKSLNILYPPKIKTPFENITVTNIGEWVVLSCEVDSNPQASIRWYKTHFGTSKNTRSINWYYQTSTINLNEVTVIENMISSTSYHKFQVVNEYDLDIYICEAQASTFQKIYKYVVVAKKEEPTIKVEQATIKVENDGIASLMCLVESWPKPSPSNIKWYFETSELAIISTERRYLINKRQLMGVESKLFFKKVIDSDYGTYTCSFSYGKTIVTKQIHLLPLKNKFIIFISIGALGVLVLLIIAVAIICACKKGTSKKRKCKKTPLQKIMLPSPTIDSSIDNEIFINQINSIPGYQKENGLNESIVLPSNRCFVFRNQPNVQKMSFSGDSRNGQDDKSTTKGNE--RSWDSGVGADDTVYRNGQHFQNIRGSNIVSPFSTLASSNNSIGPVNMNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM 868          

Query: 2264 MNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM 2668
            MNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM
Sbjct:    1 MNHIPNRYWQSYQPIELISQQNPETSSSRLSNNETSNFNGSNHSSFLPAQDETHIPMIATSANQSFVCIPIEEYQHHMRILQESQGPPSLRSFSIASYSTNNGGNSTFHPNYRPQNGNVSPTDVSVKSTSTNSKM 135