Kinase-like domain-containing protein

Overview
NameKinase-like domain-containing protein
Smed IDSMED30004904
Length (bp)2285
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Kinase-like domain-containing protein (SMED30004904) t-SNE clustered cells

Violin plots show distribution of expression levels for Kinase-like domain-containing protein (SMED30004904) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Kinase-like domain-containing protein (SMED30004904) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Kinase-like domain-containing protein (SMED30004904) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30004904

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30004904SMESG000044282.1 SMESG000028538.1 SMESG000017670.1 SmedASXL_015562SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
parenchymal cellSMED30004904SMESG000044282.1 SMESG000028538.1 SMESG000017670.1 dd_Smed_v4_17887_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
copulatory apparatusSMED30004904SMESG000044282.1 SMESG000017670.1 SMESG000008316.1 Contig7370newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Human
Match: TTK (TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401])

HSP 1 Score: 106.686 bits (265), Expect = 5.605e-23
Identity = 102/365 (27.95%), Postives = 163/365 (44.66%), Query Frame = 2 
Query: 1238 KNMLKTPKKTAMNNISSYIISPIVK--FQGNIDSS--------YVDDNVDIEASIILNYDV--DSQIDNIINLTERTSKILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPK---------KCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLT--NKRYSIFKPDSKKLTP-----LLRQIMDMCLVYEFKQRPSVEELL 2239
            K++ KTP    +++  S   +P+VK  F      S        +      I A+ + N  V   S  +  I++  R   IL       K IG GG SKV+  + +  +Q YA+K +  E  +N  +     EI  +  +   ++  IRL D  I D+   +VME    D+ +++++K+  I P     YW  ML  V  +H   I H DLK  NF++ +   +KLIDFGI+ Q+  DT+ +      GT  +M PE +   S              K DVW++G +LY + Y   P                F Q++   +K ++I  P+ +   P      L+ ++  CL  + KQR S+ ELL
Sbjct:  448 KSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQLSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSIL-------KQIGSGGSSKVFQVLNEK-KQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKK-SIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDG-MLKLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTP----------------FQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELL 786
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Human
Match: TTK (TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401])

HSP 1 Score: 106.301 bits (264), Expect = 5.795e-23
Identity = 102/365 (27.95%), Postives = 163/365 (44.66%), Query Frame = 2 
Query: 1238 KNMLKTPKKTAMNNISSYIISPIVK--FQGNIDSS--------YVDDNVDIEASIILNYDV--DSQIDNIINLTERTSKILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPK---------KCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLT--NKRYSIFKPDSKKLTP-----LLRQIMDMCLVYEFKQRPSVEELL 2239
            K++ KTP    +++  S   +P+VK  F      S        +      I A+ + N  V   S  +  I++  R   IL       K IG GG SKV+  + +  +Q YA+K +  E  +N  +     EI  +  +   ++  IRL D  I D+   +VME    D+ +++++K+  I P     YW  ML  V  +H   I H DLK  NF++ +   +KLIDFGI+ Q+  DT+ +      GT  +M PE +   S              K DVW++G +LY + Y   P                F Q++   +K ++I  P+ +   P      L+ ++  CL  + KQR S+ ELL
Sbjct:  447 KSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQLSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSIL-------KQIGSGGSSKVFQVLNEK-KQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKK-SIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDG-MLKLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTP----------------FQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELL 785
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Human
Match: TTK (TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401])

HSP 1 Score: 106.301 bits (264), Expect = 5.795e-23
Identity = 102/365 (27.95%), Postives = 163/365 (44.66%), Query Frame = 2 
Query: 1238 KNMLKTPKKTAMNNISSYIISPIVK--FQGNIDSS--------YVDDNVDIEASIILNYDV--DSQIDNIINLTERTSKILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPK---------KCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLT--NKRYSIFKPDSKKLTP-----LLRQIMDMCLVYEFKQRPSVEELL 2239
            K++ KTP    +++  S   +P+VK  F      S        +      I A+ + N  V   S  +  I++  R   IL       K IG GG SKV+  + +  +Q YA+K +  E  +N  +     EI  +  +   ++  IRL D  I D+   +VME    D+ +++++K+  I P     YW  ML  V  +H   I H DLK  NF++ +   +KLIDFGI+ Q+  DT+ +      GT  +M PE +   S              K DVW++G +LY + Y   P                F Q++   +K ++I  P+ +   P      L+ ++  CL  + KQR S+ ELL
Sbjct:  447 KSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQLSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSIL-------KQIGSGGSSKVFQVLNEK-KQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKK-SIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDG-MLKLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTP----------------FQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELL 785
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Human
Match: STK36 (serine/threonine kinase 36 [Source:HGNC Symbol;Acc:HGNC:17209])

HSP 1 Score: 92.0485 bits (227), Expect = 7.055e-20
Identity = 74/268 (27.61%), Postives = 134/268 (50.00%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVI--VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQE--KQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEP--KKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELL 2239
            Y   ++IGEG   +VY    K+  Q  A+K I  +  +   +++++ EI+IM  +   N  + ++DS   DK  V+V + A+ ++   +++  K P+   D +      ++  +  LH  RI H D+K QN ++ +   IKL DFG +R +S +T +++     GT ++MSPEL+    E  P     D+W++G +LY L     P        YA++  Q  S +L +    +  P +  ++P  +  +   L  + +QR S  +LL
Sbjct:    4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPN-IVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPE---DQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTS--IKGTPLYMSPELV----EERPYDHTADLWSVGCILYELAVGTPP-------FYATSIFQLVSLILKD---PVRWPST--ISPCFKNFLQGLLTKDPRQRLSWPDLL 249
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Human
Match: NEK6 (NIMA related kinase 6 [Source:HGNC Symbol;Acc:HGNC:7749])

HSP 1 Score: 92.4337 bits (228), Expect = 9.990e-20
Identity = 80/270 (29.63%), Postives = 134/270 (49.63%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVK-VIVFE--NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKC-DMKTFIQ--EKQPDISPD-FILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKS-EFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQL----LTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSV 2227
            ++ +K IG G  S+VY A    DR+T A+K V +FE  +    +D   EI ++  ++  N  I+ +DS I D    IV+E A   D+   I+  +KQ  + P+  + KY+  +   V+ +H +R+ H D+K  N  +T +  +KL D G+ R  S +T+  +     GT  +MSPE +      F   K D+W++G +LY +     P +  G+K+   + CQ   Q     L  + YS            LR+++ MC+  +  QRP +
Sbjct:   45 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN-IIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETT--AAHSLVGTPYYMSPERIHENGYNF---KSDIWSLGCLLYEMAALQSPFY--GDKMNLFSLCQKIEQCDYPPLPGEHYS----------EKLRELVSMCICPDPHQRPDI 296
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Celegans
Match: ZK524.4 (pep chromosome:WBcel235:I:7460858:7466424:-1 gene:WBGene00013994.1 transcript:ZK524.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK524.4)

HSP 1 Score: 79.7221 bits (195), Expect = 5.615e-15
Identity = 72/272 (26.47%), Postives = 127/272 (46.69%), Query Frame = 2 
Query: 1442 LFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVET-----EIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTES-ERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELL 2239
            + G Y+ +K IG+G  + V  A      +  AVK+I   +   M +  T     E++ M ++   N  +RL + L       +++E    D+  FI + +  +      +Y+  ++  +   H   + H DLK +N V  E    +KL DFG S        L     S G+  + +PE+L G S ++    DVW++G++LY L+    P F+  N        +  +++L  K YSI  PD   L+   R ++   LV E ++R S+E+++
Sbjct:   23 IAGLYDLEKTIGQGHFAVVKLAKHVFTGEMVAVKII---DKTKMDEASTSQIMKEVRCMKLVQHANI-VRLYEVLDTQTKIFLILELGDYDLHDFIIKHEKGVCESLAQQYFCQIMTAIDYCHQLHVVHRDLKPENVVFFEKLGMVKLTDFGFSNSYEPGEQL---NTSCGSLAYSAPEILLGDS-YDAPAVDVWSLGVILYMLVCGRLP-FQEAND------SETLTKILDCK-YSI--PDV--LSDECRNLIQSMLVREPQKRASLEKIV 274
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Celegans
Match: nekl-3 (Serine/threonine-protein kinase nekl-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EFM9])

HSP 1 Score: 76.6406 bits (187), Expect = 6.044e-15
Identity = 83/293 (28.33%), Postives = 138/293 (47.10%), Query Frame = 2 
Query: 1397 QIDNIINLTERTS-KILFGSYECQKLIGEGGMSKVYSAIGKH-DRQTYAVKVIVFE--NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKC-DMKTFIQ--EKQPDISPD-FILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL--SGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKL 2245
            +I NI N  +    K+    +  +K IG+G  S+V+ A     D      K+ VFE  +    +D   EI ++  ++  N  IR   S I +    IV+E A+  DM   I+  +K   + P+  I KY+  + R +  +H KRI H D+K  N  +T +  +KL D G+ R  S  T+  +     GT  +MSPE +  SG +     K D+W+ G +LY +     P +  G+K+   + C+     + N  Y     D    +  LR ++  C++ E  +RP   E+L++
Sbjct:    3 KISNIYNFDDPPPDKLSLELFIIEKKIGKGQFSEVFRAQCTWVDLHVALKKIQVFEMVDQKARQDCLKEIDLLKQLNHVN-VIRYYASFIDNNQLNIVLELAEAGDMSRMIKHFKKGGRLIPEKTIWKYFVQLARALAHMHSKRIMHRDIKPANVFITGNGIVKLGDLGLGRFFSSKTT--AAHSLVGTPYYMSPERIQESGYNF----KSDLWSTGCLLYEMAALQSPFY--GDKMNLYSLCKK----IENCEYPPLPADI--YSTQLRDLVSRCILPEASKRPETSEVLQV 280
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Celegans
Match: nekl-3 (Serine/threonine-protein kinase nekl-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EFM9])

HSP 1 Score: 76.6406 bits (187), Expect = 6.044e-15
Identity = 83/293 (28.33%), Postives = 138/293 (47.10%), Query Frame = 2 
Query: 1397 QIDNIINLTERTS-KILFGSYECQKLIGEGGMSKVYSAIGKH-DRQTYAVKVIVFE--NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKC-DMKTFIQ--EKQPDISPD-FILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL--SGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKL 2245
            +I NI N  +    K+    +  +K IG+G  S+V+ A     D      K+ VFE  +    +D   EI ++  ++  N  IR   S I +    IV+E A+  DM   I+  +K   + P+  I KY+  + R +  +H KRI H D+K  N  +T +  +KL D G+ R  S  T+  +     GT  +MSPE +  SG +     K D+W+ G +LY +     P +  G+K+   + C+     + N  Y     D    +  LR ++  C++ E  +RP   E+L++
Sbjct:    3 KISNIYNFDDPPPDKLSLELFIIEKKIGKGQFSEVFRAQCTWVDLHVALKKIQVFEMVDQKARQDCLKEIDLLKQLNHVN-VIRYYASFIDNNQLNIVLELAEAGDMSRMIKHFKKGGRLIPEKTIWKYFVQLARALAHMHSKRIMHRDIKPANVFITGNGIVKLGDLGLGRFFSSKTT--AAHSLVGTPYYMSPERIQESGYNF----KSDLWSTGCLLYEMAALQSPFY--GDKMNLYSLCKK----IENCEYPPLPADI--YSTQLRDLVSRCILPEASKRPETSEVLQV 280
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Celegans
Match: unc-82 (pep chromosome:WBcel235:IV:7425729:7444660:1 gene:WBGene00006814.1 transcript:B0496.3g.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-82)

HSP 1 Score: 79.337 bits (194), Expect = 7.989e-15
Identity = 69/258 (26.74%), Postives = 132/258 (51.16%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAI-GKHDRQTYAVKVI---VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVME-KAKCDMKTFIQE--KQPDISPDFILKYWT-AMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTN-KRYSIFKPDSKKLTPLLRQIMDMCLV 2200
            +E  K +G G   KV  A   K DR+  AVK+I     E+   +  +  EI+IM+ ++  N  I++ +        ++VME  +  ++  ++      P+     I +  T A+L C    H  R++H DLKL+N ++ ++   K+ DFG+S   + D +L++     G+ ++ SPE+++G + ++  + D W++GI+LYTL+Y   P              ++F++++   KR + F+P++     +L  I +M  V
Sbjct:   58 FEITKKLGSGTYGKVSLAYDHKFDREV-AVKLIKKSAIESKADLVRIRREIRIMSALNHPN-IIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQITSAVLYC----HKHRVAHRDLKLENILLDQNNNAKIADFGLSNYFA-DKNLLTT--FCGSPLYASPEIING-TPYKGPEVDCWSLGILLYTLVYGSMP-----------FDGRDFNRMVRQIKRGAYFEPETPSTASML--IRNMLRV 292
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Celegans
Match: unc-82 (pep chromosome:WBcel235:IV:7428926:7444648:1 gene:WBGene00006814.1 transcript:B0496.3f.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-82)

HSP 1 Score: 79.337 bits (194), Expect = 7.998e-15
Identity = 69/258 (26.74%), Postives = 132/258 (51.16%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAI-GKHDRQTYAVKVI---VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVME-KAKCDMKTFIQE--KQPDISPDFILKYWT-AMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTN-KRYSIFKPDSKKLTPLLRQIMDMCLV 2200
            +E  K +G G   KV  A   K DR+  AVK+I     E+   +  +  EI+IM+ ++  N  I++ +        ++VME  +  ++  ++      P+     I +  T A+L C    H  R++H DLKL+N ++ ++   K+ DFG+S   + D +L++     G+ ++ SPE+++G + ++  + D W++GI+LYTL+Y   P              ++F++++   KR + F+P++     +L  I +M  V
Sbjct:   58 FEITKKLGSGTYGKVSLAYDHKFDREV-AVKLIKKSAIESKADLVRIRREIRIMSALNHPN-IIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQITSAVLYC----HKHRVAHRDLKLENILLDQNNNAKIADFGLSNYFA-DKNLLTT--FCGSPLYASPEIING-TPYKGPEVDCWSLGILLYTLVYGSMP-----------FDGRDFNRMVRQIKRGAYFEPETPSTASML--IRNMLRV 292
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Fly
Match: Mps1 (gene:FBgn0000063 transcript:FBtr0083478)

HSP 1 Score: 109.768 bits (273), Expect = 1.398e-24
Identity = 89/286 (31.12%), Postives = 138/286 (48.25%), Query Frame = 2 
Query: 1436 KILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNL-VMKDVETEIKIMTIMSSTNYAIRLID-SLIGDKGAV-IVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL----SGKSEF----EPK-----KCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTP-LLRQIMDMCLVYEFKQRPSVEELLK 2242
            KI    Y   K +G GG S V+ A        +A+KV+  + +  V++    E K++  +      + L D  L+ ++  + +VMEK  CD+   +Q    ++    ++     ML+ V  +H   + H DLK  NF+M  S R+KLIDFGI+  +++D++ I     +GTF ++SPE L    +G S      +PK     K DVW++G +LY L+Y   P F     VYA  S       +T    SI  P      P +L  +   CL    K+RPS  ELL+
Sbjct:  331 KIKNHEYTIDKKLGCGGSSSVFLARRSDSGNEFALKVVDLQADPQVVQGYLNETKLLAKLQGNVCVVALYDYQLVREESKLYMVMEKGDCDLNKILQSYTTNLPLYSLMNILYQMLQAVNYIHQHGVIHSDLKPANFLMV-SGRLKLIDFGIASNIAVDSTSIIKFSQAGTFNYISPEALTDTSTGNSPMRRADQPKIKISTKSDVWSLGCILYLLLYQKTP-FGHIRNVYAKMSA------ITTPGTSIEYPAIPPYYPIMLVHMAKNCLQLNPKKRPSCTELLQ 608
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Fly
Match: Mps1 (gene:FBgn0000063 transcript:FBtr0331348)

HSP 1 Score: 100.138 bits (248), Expect = 2.119e-21
Identity = 74/236 (31.36%), Postives = 118/236 (50.00%), Query Frame = 2 
Query: 1436 KILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNL-VMKDVETEIKIMTIMSSTNYAIRLID-SLIGDKGAV-IVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL----SGKSEF----EPK-----KCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSC 2095
            KI    Y   K +G GG S V+ A        +A+KV+  + +  V++    E K++  +      + L D  L+ ++  + +VMEK  CD+   +Q    ++    ++     ML+ V  +H   + H DLK  NF+M  S R+KLIDFGI+  +++D++ I     +GTF ++SPE L    +G S      +PK     K DVW++G +LY L+Y   P F     VYA  S 
Sbjct:  331 KIKNHEYTIDKKLGCGGSSSVFLARRSDSGNEFALKVVDLQADPQVVQGYLNETKLLAKLQGNVCVVALYDYQLVREESKLYMVMEKGDCDLNKILQSYTTNLPLYSLMNILYQMLQAVNYIHQHGVIHSDLKPANFLMV-SGRLKLIDFGIASNIAVDSTSIIKFSQAGTFNYISPEALTDTSTGNSPMRRADQPKIKISTKSDVWSLGCILYLLLYQKTP-FGHIRNVYAKMSA 564
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Fly
Match: Nuak1 (gene:FBgn0262617 transcript:FBtr0305354)

HSP 1 Score: 82.0333 bits (201), Expect = 1.467e-15
Identity = 74/292 (25.34%), Postives = 137/292 (46.92%), Query Frame = 2 
Query: 1397 QIDNIINLTERTSKI--------LFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIV---FENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVME-KAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEEL 2236
            QIDNI++    T  +        L   ++  K +G+G   KV   I K   Q  A+K I     E    +  +  E++IM+ +   N  I + +     +  V+VME  A  ++  ++ E++  ++ +   + +  +   V   H  +I H DLKL+N ++ E    K+ DFG+S     D  L+  G   G+ ++ SPE++ G + ++  + D W++G++LYTL+Y   P   S  K           Q+     Y   KP   + + L+R ++ +C     ++R S+E++
Sbjct:   43 QIDNIMSGIANTGNVKMNNHRKKLRQRFDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNI-IHIYEVFENREKMVLVMEFAAGGELYDYLSERK-VLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFD-DQRLL--GTFCGSPLYASPEIVEG-TPYQGPEVDCWSLGVLLYTLVYGSMPFDGSNFKRL-------VKQISQGDYYEPRKPS--RASTLIRDMLTVCP----RKRASIEQI 315
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Fly
Match: Nuak1 (gene:FBgn0262617 transcript:FBtr0305353)

HSP 1 Score: 82.0333 bits (201), Expect = 1.467e-15
Identity = 74/292 (25.34%), Postives = 137/292 (46.92%), Query Frame = 2 
Query: 1397 QIDNIINLTERTSKI--------LFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIV---FENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVME-KAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEEL 2236
            QIDNI++    T  +        L   ++  K +G+G   KV   I K   Q  A+K I     E    +  +  E++IM+ +   N  I + +     +  V+VME  A  ++  ++ E++  ++ +   + +  +   V   H  +I H DLKL+N ++ E    K+ DFG+S     D  L+  G   G+ ++ SPE++ G + ++  + D W++G++LYTL+Y   P   S  K           Q+     Y   KP   + + L+R ++ +C     ++R S+E++
Sbjct:   43 QIDNIMSGIANTGNVKMNNHRKKLRQRFDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNI-IHIYEVFENREKMVLVMEFAAGGELYDYLSERK-VLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFD-DQRLL--GTFCGSPLYASPEIVEG-TPYQGPEVDCWSLGVLLYTLVYGSMPFDGSNFKRL-------VKQISQGDYYEPRKPS--RASTLIRDMLTVCP----RKRASIEQI 315
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Fly
Match: Nuak1 (gene:FBgn0262617 transcript:FBtr0305352)

HSP 1 Score: 82.0333 bits (201), Expect = 1.467e-15
Identity = 74/292 (25.34%), Postives = 137/292 (46.92%), Query Frame = 2 
Query: 1397 QIDNIINLTERTSKI--------LFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIV---FENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVME-KAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEEL 2236
            QIDNI++    T  +        L   ++  K +G+G   KV   I K   Q  A+K I     E    +  +  E++IM+ +   N  I + +     +  V+VME  A  ++  ++ E++  ++ +   + +  +   V   H  +I H DLKL+N ++ E    K+ DFG+S     D  L+  G   G+ ++ SPE++ G + ++  + D W++G++LYTL+Y   P   S  K           Q+     Y   KP   + + L+R ++ +C     ++R S+E++
Sbjct:   43 QIDNIMSGIANTGNVKMNNHRKKLRQRFDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNI-IHIYEVFENREKMVLVMEFAAGGELYDYLSERK-VLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFD-DQRLL--GTFCGSPLYASPEIVEG-TPYQGPEVDCWSLGVLLYTLVYGSMPFDGSNFKRL-------VKQISQGDYYEPRKPS--RASTLIRDMLTVCP----RKRASIEQI 315
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Zebrafish
Match: ttk (ttk protein kinase [Source:NCBI gene;Acc:317763])

HSP 1 Score: 101.679 bits (252), Expect = 1.356e-21
Identity = 81/278 (29.14%), Postives = 132/278 (47.48%), Query Frame = 2 
Query: 1466 KLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLS-GKSEFEP-----KKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQ-----IMDMCLVYEFKQRPSVEELLKLISLQ 2257
            K+IG GG SKVY  +  H +  YAVK +  E  +   ++  + EI+ +  +   ++  I+L D  I      ++ME    D+ T+++ ++  + P     YW  ML  V  +H   I H DLK  NF++ +   +KLIDFGI+ Q+  D + I      GT  +M PE +    S  +P      K DVW++G +LY +              Y  T  QN +  ++ K ++I  P  +   P + +     ++  CLV   ++R S+ ELL    LQ
Sbjct:  658 KMIGRGGSSKVYQ-VFDHKKHVYAVKYVNLEEADAQAVESYKNEIEHLNHLQQYSDQIIKLYDYEITSSYIYMLMECGHLDLNTWLRNRK-TVKPLDRKAYWRNMLEAVHTIHKHGIVHSDLKPANFLIVDGS-LKLIDFGIANQIQPDVTSIMKDSQVGTLNYMPPEAIKDTSSNGKPGSKISAKGDVWSLGCILYCM-------------TYGKTPFQNITNQIS-KIHAIIDPSHEIDFPDIPEKDLLDVLKKCLVRNPRERISIAELLDHPYLQ 918
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Zebrafish
Match: ttk (ttk protein kinase [Source:NCBI gene;Acc:317763])

HSP 1 Score: 101.679 bits (252), Expect = 1.367e-21
Identity = 81/278 (29.14%), Postives = 132/278 (47.48%), Query Frame = 2 
Query: 1466 KLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLS-GKSEFEP-----KKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQ-----IMDMCLVYEFKQRPSVEELLKLISLQ 2257
            K+IG GG SKVY  +  H +  YAVK +  E  +   ++  + EI+ +  +   ++  I+L D  I      ++ME    D+ T+++ ++  + P     YW  ML  V  +H   I H DLK  NF++ +   +KLIDFGI+ Q+  D + I      GT  +M PE +    S  +P      K DVW++G +LY +              Y  T  QN +  ++ K ++I  P  +   P + +     ++  CLV   ++R S+ ELL    LQ
Sbjct:  657 KMIGRGGSSKVYQ-VFDHKKHVYAVKYVNLEEADAQAVESYKNEIEHLNHLQQYSDQIIKLYDYEITSSYIYMLMECGHLDLNTWLRNRK-TVKPLDRKAYWRNMLEAVHTIHKHGIVHSDLKPANFLIVDGS-LKLIDFGIANQIQPDVTSIMKDSQVGTLNYMPPEAIKDTSSNGKPGSKISAKGDVWSLGCILYCM-------------TYGKTPFQNITNQIS-KIHAIIDPSHEIDFPDIPEKDLLDVLKKCLVRNPRERISIAELLDHPYLQ 917
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Zebrafish
Match: tssk6 (testis-specific serine kinase 6 [Source:ZFIN;Acc:ZDB-GENE-060216-3])

HSP 1 Score: 84.3445 bits (207), Expect = 1.446e-17
Identity = 58/198 (29.29%), Postives = 103/198 (52.02%), Query Frame = 2 
Query: 1472 IGEGGMSKVYSAIGKHDRQTYAVKVI---VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSL-IGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQP 2053
            IGEG  S+V  A  +      A+K++       + + K +  E+ ++  ++  N  I++ + + +  K   IVME A+ D+   I E    I  D     +  M+  +  LH   I H DLK +N ++T  E+IK+ DFG +R +  D S +S     G+  +  PE+++G + ++PKK DVW++G++LY ++    P
Sbjct:   18 IGEGSFSRVKLATSQKHCCKVAIKIVDRMRGSADFIQKFLPRELAVLRRVNHEN-IIQMFECIEVAGKRLCIVMEAAEKDLLQKIHEVH-HIPKDLSKTMFAQMVSAINYLHQMNIVHRDLKCENILLTADEKIKIADFGFARFVE-DPSELSH-TFCGSRAYTPPEVITG-TPYDPKKYDVWSLGVILYVMVTGTMP 210
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-117c9.1 (si:ch211-117c9.1 [Source:ZFIN;Acc:ZDB-GENE-110411-282])

HSP 1 Score: 83.1889 bits (204), Expect = 4.785e-17
Identity = 63/208 (30.29%), Postives = 106/208 (50.96%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE---NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKC-DMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGIS----RQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQP 2053
            +E  + +G G   KV  A+ +   +T A+K I  E   N+L    ++ EI+I + +   N  IRL +     +  V+VME A   ++  +IQ+KQ  +S D    ++  +   V   H   + H DLKL+N ++ +   +KL DFG+S    R   LDT         G+ ++ SPE+++G     P + D W++G++LY L+Y   P
Sbjct:   34 FEVLETLGRGTYGKVKRAVERQYGKTVAIKSIRKERLRNDLDRAHIQREIEITSSLVHPN-IIRLYEVFESRERIVMVMEYASGGELYEYIQDKQ-RLSEDEARHFFRQITSAVHYCHQNGVVHRDLKLENILLDKDLTVKLADFGLSNRYMRGRCLDT-------FCGSPLYASPEIINGLPYHGP-EVDCWSLGVLLYALVYGSMP 231
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Zebrafish
Match: CABZ01040556.1 (NIMA related kinase 3 [Source:NCBI gene;Acc:100536894])

HSP 1 Score: 82.0333 bits (201), Expect = 5.155e-16
Identity = 65/207 (31.40%), Postives = 100/207 (48.31%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVF-ENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCD--MKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLY---TLIYNFQPR 2056
            Y   ++IGEG   +       H+ + Y +K I   +    MK   +E  +++ M   N  +   DS   D    IVME       M+   Q+ +   S + ILK++  M    K +HDKR+ H DLK +N  +T+S  +K+ DFG +   SL+++        GT  ++SPE+   K      K DVW++G VLY   TL + FQ R
Sbjct:    4 YSVVRVIGEGSFGRALLVQPIHEEKHYVMKEIRLPKAESGMKKSRSEAVLLSKMKHPN-IVAFRDSFEADGHLYIVMEFCSGGDLMQRIRQQNRLLFSEEQILKWFAQMCLGTKHIHDKRVLHRDLKSKNIFLTDSGTVKVGDFGSA--CSLNSAKAYAQTYVGTPYYVSPEIWDNKP--YNNKSDVWSLGCVLYELCTLQHPFQAR 205
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Xenopus
Match: ttk (TTK protein kinase [Source:NCBI gene;Acc:780054])

HSP 1 Score: 105.145 bits (261), Expect = 1.538e-22
Identity = 85/280 (30.36%), Postives = 135/280 (48.21%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL--------SGK--SEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPL-----LRQIMDMCLVYEFKQRPSVEELL 2239
            Y   K IG GG SKV+  +    +  YA+K +  +  +   ++  + EI  +  +   ++  IRL D  I D+   +VME    D+ T++++K+  I+P     YW  ML  V  +H   I H DLK  NF++ +   +KLIDFGI+ Q+  D + I      GT  +M PE +        +GK  S+  PK  DVW++G +LY +              Y  T  Q+ +  +T K ++I  P  +   P      L+ ++  CLV   K+R S+ ELL
Sbjct:  543 YAVLKQIGTGGSSKVFQVMDD-KKHLYAIKYVNLQEADQQTIESYQNEISHLNKLQQHSDKIIRLYDYEITDQHIYMVMECGNIDLNTWLRKKK-AINPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDG-MLKLIDFGIANQIQPDVTSIVKDSQVGTINYMPPEAIKDTTTYAENGKPRSKISPKG-DVWSLGCILYCM-------------TYGKTPFQHITNQIT-KLHAILDPGYEIEFPNIPEKDLQDVLRKCLVRNPKERISIAELL 804
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Xenopus
Match: ttk (TTK protein kinase [Source:NCBI gene;Acc:780054])

HSP 1 Score: 103.99 bits (258), Expect = 1.710e-22
Identity = 85/280 (30.36%), Postives = 135/280 (48.21%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL--------SGK--SEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPL-----LRQIMDMCLVYEFKQRPSVEELL 2239
            Y   K IG GG SKV+  +    +  YA+K +  +  +   ++  + EI  +  +   ++  IRL D  I D+   +VME    D+ T++++K+  I+P     YW  ML  V  +H   I H DLK  NF++ +   +KLIDFGI+ Q+  D + I      GT  +M PE +        +GK  S+  PK  DVW++G +LY +              Y  T  Q+ +  +T K ++I  P  +   P      L+ ++  CLV   K+R S+ ELL
Sbjct:  285 YAVLKQIGTGGSSKVFQVMDD-KKHLYAIKYVNLQEADQQTIESYQNEISHLNKLQQHSDKIIRLYDYEITDQHIYMVMECGNIDLNTWLRKKKA-INPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDG-MLKLIDFGIANQIQPDVTSIVKDSQVGTINYMPPEAIKDTTTYAENGKPRSKISPKG-DVWSLGCILYCM-------------TYGKTPFQHITNQIT-KLHAILDPGYEIEFPNIPEKDLQDVLRKCLVRNPKERISIAELL 546
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Xenopus
Match: ttk (TTK protein kinase [Source:NCBI gene;Acc:780054])

HSP 1 Score: 103.219 bits (256), Expect = 1.968e-22
Identity = 85/280 (30.36%), Postives = 135/280 (48.21%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL--------SGK--SEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPL-----LRQIMDMCLVYEFKQRPSVEELL 2239
            Y   K IG GG SKV+  +    +  YA+K +  +  +   ++  + EI  +  +   ++  IRL D  I D+   +VME    D+ T++++K+  I+P     YW  ML  V  +H   I H DLK  NF++ +   +KLIDFGI+ Q+  D + I      GT  +M PE +        +GK  S+  PK  DVW++G +LY +              Y  T  Q+ +  +T K ++I  P  +   P      L+ ++  CLV   K+R S+ ELL
Sbjct:  188 YAVLKQIGTGGSSKVFQVMDD-KKHLYAIKYVNLQEADQQTIESYQNEISHLNKLQQHSDKIIRLYDYEITDQHIYMVMECGNIDLNTWLRKKKA-INPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDG-MLKLIDFGIANQIQPDVTSIVKDSQVGTINYMPPEAIKDTTTYAENGKPRSKISPKG-DVWSLGCILYCM-------------TYGKTPFQHITNQIT-KLHAILDPGYEIEFPNIPEKDLQDVLRKCLVRNPKERISIAELL 449
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Xenopus
Match: lhfpl4 (LHFPL tetraspan subfamily member 4 [Source:Xenbase;Acc:XB-GENE-1013189])

HSP 1 Score: 98.5969 bits (244), Expect = 1.919e-20
Identity = 66/211 (31.28%), Postives = 109/211 (51.66%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVI--VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDM-------KTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRF 2059
            Y    LIGEG   +VY    KH  +  A+K I  V  +   +K ++ EI+IM  +   N  +R++DS   ++  V+V E A+ ++         F +E   DIS   +   +         LH  RI H D+K QN ++++   +KL DFG +R+LSLDT ++   +  GT ++MSPEL+  +      + D+WA+G ++Y L+    P +
Sbjct:    4 YHVLDLIGEGSFGRVYKGRRKHSGEVVALKFIPKVGRSEKELKGLKREIQIMRDLRHPNI-VRMLDSCETEREVVVVTEYAEGELFKILEDDGHFPEELVRDISAQLVSALYY--------LHSHRILHRDMKPQNILLSKDGTVKLCDFGFARELSLDTLMVRSIK--GTPLYMSPELILERP--YDHRSDLWALGCIVYELLVGTPPFY 201
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Xenopus
Match: lhfpl4 (LHFPL tetraspan subfamily member 4 [Source:Xenbase;Acc:XB-GENE-1013189])

HSP 1 Score: 98.5969 bits (244), Expect = 2.184e-20
Identity = 66/211 (31.28%), Postives = 109/211 (51.66%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVI--VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDM-------KTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRF 2059
            Y    LIGEG   +VY    KH  +  A+K I  V  +   +K ++ EI+IM  +   N  +R++DS   ++  V+V E A+ ++         F +E   DIS   +   +         LH  RI H D+K QN ++++   +KL DFG +R+LSLDT ++   +  GT ++MSPEL+  +      + D+WA+G ++Y L+    P +
Sbjct:    4 YHVLDLIGEGSFGRVYKGRRKHSGEVVALKFIPKVGRSEKELKGLKREIQIMRDLRHPNI-VRMLDSCETEREVVVVTEYAEGELFKILEDDGHFPEELVRDISAQLVSALYY--------LHSHRILHRDMKPQNILLSKDGTVKLCDFGFARELSLDTLMVRSIK--GTPLYMSPELILERP--YDHRSDLWALGCIVYELLVGTPPFY 201
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Mouse
Match: Ttk (Ttk protein kinase [Source:MGI Symbol;Acc:MGI:1194921])

HSP 1 Score: 105.916 bits (263), Expect = 6.473e-23
Identity = 88/298 (29.53%), Postives = 145/298 (48.66%), Query Frame = 2 
Query: 1394 SQIDNIINLTERTSKILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFEN--NLVMKDVETEIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSG----------KSEFEPKKCDVWAMGIVLYTLIYN---FQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELL 2239
            S I+  I++  R   IL       K IG GG SKV+  + +  +Q  A+K +  E+  +  ++    EI  +  +   ++  IRL D  I ++   +VME    D+ +++++K+  I+P     YW  ML  V  +H   I H DLK  NFV+ +   +KLIDFGI+ Q+  DT+ I      GT  +M+PE +            +++  P + DVW++G +LY + Y    FQ      +K++A          + N  + I  P+  +    LR ++  CLV   K+R S+ ELL
Sbjct:  485 SSINECISVNGRIYSIL-------KQIGSGGSSKVFQVLNEK-KQINAIKYVNLEDADSQTIESYRNEIAFLNKLQQHSDKIIRLYDYEITEQYIYMVMECGNIDLNSWLKKKK-SINPWERKSYWKNMLEAVHIIHQHGIVHSDLKPANFVIVDG-MLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSSRENSKIRTKVSP-RSDVWSLGCILYYMTYGRTPFQHIINQVSKLHA----------IINPAHEIEFPEISEKD--LRDVLKCCLVRNPKERISIPELL 759
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Mouse
Match: Nek6 (NIMA (never in mitosis gene a)-related expressed kinase 6 [Source:MGI Symbol;Acc:MGI:1891638])

HSP 1 Score: 89.7373 bits (221), Expect = 4.902e-19
Identity = 79/270 (29.26%), Postives = 133/270 (49.26%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVK-VIVFE--NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKC-DMKTFIQ--EKQPDISPD-FILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKS-EFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQL----LTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSV 2227
            ++ +K IG G  S+VY A    DR+T A+K V +FE  +    +D   EI ++  ++  N  I+ +DS I D    IV+E A   D+   I+  +KQ  + P+  + KY+  +   V+ +H +R+ H D+K  N  +T +  +KL D G+ R  S +T+  +     GT  +MSPE +      F   K D+W++G +LY +     P +  G+K+   + CQ   Q     L  + YS            LR+++ MC+  +   RP +
Sbjct:   34 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN-IIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETT--AAHSLVGTPYYMSPERIHENGYNF---KSDIWSLGCLLYEMAALQSPFY--GDKMNLFSLCQKIEQCDYPPLPGEHYS----------EKLRELVSMCIYPDPDHRPDI 285
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Mouse
Match: Nek6 (NIMA (never in mitosis gene a)-related expressed kinase 6 [Source:MGI Symbol;Acc:MGI:1891638])

HSP 1 Score: 89.7373 bits (221), Expect = 5.495e-19
Identity = 79/273 (28.94%), Postives = 133/273 (48.72%), Query Frame = 2 
Query: 1445 FGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVK-VIVFE--NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKC-DMKTFIQ--EKQPDISPD-FILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKS-EFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQL----LTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSV 2227
               ++ +K IG G  S+VY A    DR+T A+K V +FE  +    +D   EI ++  ++  N  I+ +DS I D    IV+E A   D+   I+  +KQ  + P+  + KY+  +   V+ +H +R+ H D+K  N  +T +  +KL D G+ R  S +T+  +     GT  +MSPE +      F   K D+W++G +LY +     P +  G+K+   + CQ   Q     L  + YS            LR+++ MC+  +   RP +
Sbjct:   42 LADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN-IIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETT--AAHSLVGTPYYMSPERIHENGYNF---KSDIWSLGCLLYEMAALQSPFY--GDKMNLFSLCQKIEQCDYPPLPGEHYS----------EKLRELVSMCIYPDPDHRPDI 296
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Mouse
Match: Nek6 (NIMA (never in mitosis gene a)-related expressed kinase 6 [Source:MGI Symbol;Acc:MGI:1891638])

HSP 1 Score: 89.7373 bits (221), Expect = 5.495e-19
Identity = 79/273 (28.94%), Postives = 133/273 (48.72%), Query Frame = 2 
Query: 1445 FGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVK-VIVFE--NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKC-DMKTFIQ--EKQPDISPD-FILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKS-EFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQL----LTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSV 2227
               ++ +K IG G  S+VY A    DR+T A+K V +FE  +    +D   EI ++  ++  N  I+ +DS I D    IV+E A   D+   I+  +KQ  + P+  + KY+  +   V+ +H +R+ H D+K  N  +T +  +KL D G+ R  S +T+  +     GT  +MSPE +      F   K D+W++G +LY +     P +  G+K+   + CQ   Q     L  + YS            LR+++ MC+  +   RP +
Sbjct:   42 LADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN-IIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETT--AAHSLVGTPYYMSPERIHENGYNF---KSDIWSLGCLLYEMAALQSPFY--GDKMNLFSLCQKIEQCDYPPLPGEHYS----------EKLRELVSMCIYPDPDHRPDI 296
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Mouse
Match: Tssk6 (testis-specific serine kinase 6 [Source:MGI Symbol;Acc:MGI:2148775])

HSP 1 Score: 88.1965 bits (217), Expect = 9.923e-19
Identity = 73/275 (26.55%), Postives = 125/275 (45.45%), Query Frame = 2 
Query: 1451 SYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFEN---NLVMKDVETEIKIMTIMSSTN--YAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESER-IKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNF-----SQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLK 2242
             Y+  + IGEG  SKV  A  K  + T A+KV+       + V K +  E+ I+  +   +  +    I+   G     IVME A  D+   +Q +   I      + ++ +   V+ LHD  + H DLK +N +++  ER +K+ DFG  RQ      L +     G+  + SPE+L G   ++PKK DVW++G+VLY ++                T C  F     + L   ++  +  PD  +L+   + ++   L +    RPS  ++ +
Sbjct:   11 GYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGK--LYIVMEAAATDLLQAVQ-RNGRIPGSQARELFSQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKITDFGFGRQAHGYPDLST--TYCGSAAYASPEVLLG-IPYDPKKYDVWSLGVVLYVMV----------------TGCMPFDDSDIAGLPRRQKRGVLYPDGLELSERCKSLIAELLQFSPSARPSAGQVAR 263
[Close]
BLAST of Kinase-like domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8SSH4|MPS1_ENCCU (Probable serine/threonine-protein kinase MPS1 homolog OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813 GN=MPS1 PE=3 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 1.277e-26
Identity = 83/262 (31.68%), Postives = 137/262 (52.29%), Query Frame = 2 
Query: 1457 ECQKLIGEGGMSKVYSAIGKHDRQTYAVK-VIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELL 2239
            E  K IG+GG SKVY  +       YA+K V +  +  ++     EI ++     T+  + +ID  +G+    I++E  + D+   I  ++  +S +FI   W  ML  VK +H +RI H DLK  NF+  +  R+KLIDFGIS+ +  DT+ I   E  GT  +MSPE ++       +  D+W++G +LY ++++  P  +  N +      Q   +L   + YS FK  SK    ++  +M  CL  + K+RP+++ LL
Sbjct:  290 EILKQIGKGGSSKVYKVL--FGSNVYALKRVELIGDEKMLSSYINEINLLYKFKGTSEIVEIIDHEVGEDYLHILLEYGETDLSKII--RKGGLSMNFIKDVWEQMLLIVKRVHIERIIHCDLKPANFLFVKG-RVKLIDFGISKVIRNDTTSILSEEQCGTVNYMSPEAVTQNKSKVARSSDIWSLGCILYEMVHSNPPLHEYPNLI------QKIQRL---QEYSEFKYTSKNKAAVM--VMKECLARDPKKRPTIDNLL 535
[Close]
BLAST of Kinase-like domain-containing protein vs. UniProt/SwissProt
Match: sp|Q54UL8|MPS1_DICDI (Probable serine/threonine-protein kinase mps1 OS=Dictyostelium discoideum OX=44689 GN=mps1 PE=3 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 2.005e-24
Identity = 83/275 (30.18%), Postives = 142/275 (51.64%), Query Frame = 2 
Query: 1466 KLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLI--GDKGAVIVMEKAKCDMKTFIQEKQ-PD-ISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQL-SLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKC-------DVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPL-----LRQIMDMCLVYEFKQRPSVEELL 2239
            + IG+GG  KVY  +   D + YA+K +   +   ++    EI+++  +      I+LID  +       ++V+E  + D+   +Q  Q P+  + +FI  YW  ML+ V  +H+++I H DLK  NFV  +   +KLIDFGI++ + S DT+ I      GT  ++SPE L   S+  PK+C       D+W++G +LY + + + P FKS            FS +++ K  +I  P  K   P+     L +++ +CL+    +RP++  LL
Sbjct:  718 EFIGKGGSGKVYKVLSG-DLKIYALKYVCLSDPNEIEAQLNEIEMLKRLRKQVNIIQLIDYEVNMAKNYILLVLEFGEIDLSKLLQRLQTPNGTNVNFIRIYWQQMLQAVHTIHEEKIIHGDLKPANFVSVQGS-LKLIDFGIAKAIQSDDTTNIVRESQIGTINYISPEALIDTSQGGPKQCMKLGRASDIWSLGCILYEMAFGYPP-FKS------------FSNIIS-KYQAIINPHHKIEFPVHPNENLLKVLKLCLIRNPHERPTIPTLL 976
[Close]
BLAST of Kinase-like domain-containing protein vs. UniProt/SwissProt
Match: sp|O94235|MPH1L_SCHPO (Serine/threonine-protein kinase mph1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mph1 PE=2 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 9.730e-24
Identity = 80/288 (27.78%), Postives = 138/288 (47.92%), Query Frame = 2 
Query: 1469 LIGEGGMSKVYSAIGKHDRQTYAVKVIVFEN--NLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDK-GAV-IVMEKAKCDMKTFIQE--KQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFE---------PKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPD----------------SKKLTPLLRQIMDMCLVYEFKQRPSVEELL 2239
            ++G+GG S VY      + + YA+K + F N     ++  + EI ++  +S  +  I+L  + + D  G + +VME  + D+   + +  K+P I+ +FI  YW  ML  V+ +HD+ I H DLK  NF++ E   +KLIDFGI++ +  DT+ I      GT  +M+PE L+  +             +  DVW++G +LY ++Y        G   +A          + N++Y I  P+                   + P L  +M  CL  + ++R ++ ELL
Sbjct:  321 VVGKGGSSMVYRIFSPDNSRLYALKEVNFINADQTTIQGYKNEIALLRKLSGNDRIIKLYAAEVNDTLGQLNMVMECGETDLANLLMKNMKKP-INLNFIRMYWEQMLEAVQVVHDQNIVHSDLKPANFLLVEGN-LKLIDFGIAKAIGNDTTNIHRDSHIGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQMVY--------GRAPFAHLKMIQAIAAIPNEQYHIHFPEVALPANAVQEKEGSLPGVTVGPDLMDVMKRCLERDQRKRLTIPELL 598
[Close]
BLAST of Kinase-like domain-containing protein vs. UniProt/SwissProt
Match: sp|P33981|TTK_HUMAN (Dual specificity protein kinase TTK OS=Homo sapiens OX=9606 GN=TTK PE=1 SV=2)

HSP 1 Score: 106.686 bits (265), Expect = 2.692e-22
Identity = 102/365 (27.95%), Postives = 163/365 (44.66%), Query Frame = 2 
Query: 1238 KNMLKTPKKTAMNNISSYIISPIVK--FQGNIDSS--------YVDDNVDIEASIILNYDV--DSQIDNIINLTERTSKILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPK---------KCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLT--NKRYSIFKPDSKKLTP-----LLRQIMDMCLVYEFKQRPSVEELL 2239
            K++ KTP    +++  S   +P+VK  F      S        +      I A+ + N  V   S  +  I++  R   IL       K IG GG SKV+  + +  +Q YA+K +  E  +N  +     EI  +  +   ++  IRL D  I D+   +VME    D+ +++++K+  I P     YW  ML  V  +H   I H DLK  NF++ +   +KLIDFGI+ Q+  DT+ +      GT  +M PE +   S              K DVW++G +LY + Y   P                F Q++   +K ++I  P+ +   P      L+ ++  CL  + KQR S+ ELL
Sbjct:  448 KSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQLSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSIL-------KQIGSGGSSKVFQVLNEK-KQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKK-SIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDG-MLKLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTP----------------FQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELL 786
[Close]
BLAST of Kinase-like domain-containing protein vs. UniProt/SwissProt
Match: sp|P35761|TTK_MOUSE (Dual specificity protein kinase TTK OS=Mus musculus OX=10090 GN=Ttk PE=1 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 5.193e-22
Identity = 88/298 (29.53%), Postives = 145/298 (48.66%), Query Frame = 2 
Query: 1394 SQIDNIINLTERTSKILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFEN--NLVMKDVETEIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSG----------KSEFEPKKCDVWAMGIVLYTLIYN---FQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELL 2239
            S I+  I++  R   IL       K IG GG SKV+  + +  +Q  A+K +  E+  +  ++    EI  +  +   ++  IRL D  I ++   +VME    D+ +++++K+  I+P     YW  ML  V  +H   I H DLK  NFV+ +   +KLIDFGI+ Q+  DT+ I      GT  +M+PE +            +++  P+  DVW++G +LY + Y    FQ      +K++A          + N  + I  P+  +    LR ++  CLV   K+R S+ ELL
Sbjct:  511 SSINECISVNGRIYSIL-------KQIGSGGSSKVFQVLNEK-KQINAIKYVNLEDADSQTIESYRNEIAFLNKLQQHSDKIIRLYDYEITEQYIYMVMECGNIDLNSWLKKKK-SINPWERKSYWKNMLEAVHIIHQHGIVHSDLKPANFVIVDG-MLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSSRENSKIRTKVSPRS-DVWSLGCILYYMTYGRTPFQHIINQVSKLHA----------IINPAHEIEFPEISEKD--LRDVLKCCLVRNPKERISIPELL 785
[Close]
BLAST of Kinase-like domain-containing protein vs. TrEMBL
Match: A0A5E4N6Y6 (Protein kinase domain,Protein kinase-like domain,Protein kinase, ATP binding site,Serine/threonine OS=Cinara cedri OX=506608 GN=CINCED_3A017682 PE=4 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 1.790e-32
Identity = 92/279 (32.97%), Postives = 149/279 (53.41%), Query Frame = 2 
Query: 1451 SYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFEN--NLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVI--VMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPE-LLSGKSEFEP----KKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSK----KLTPLLRQIMDMCLVYEFKQRPSVEELLKLI 2248
            +Y     +G GG S VY  +     Q  A+K +      +++ K    E+K++  +      IRL DS    K  ++  VMEK   D+   I+  +  +S   I+ YW+ ML  V  +H+K + H DLK  NF++  S R+KLIDFGI+ ++  D + +    ++GT+ +MSPE ++SG S F+     +K DVW++G +LY+LIY   P        + + + Q    +  +K+  IF   SK     + P+L Q M++CL+ + K RP+V +LLKLI
Sbjct:  315 NYSILNTLGHGGSSVVYEVLHPETNQVVAIKKVDLSEVEDIIAKGYLNEVKLLENLQICESVIRLFDSQYSTKEKILYMVMEKGDTDLSKLIRSTK-HMSVFMIMYYWSEMLNTVSQIHEKDVIHSDLKPANFLLV-SGRLKLIDFGIASKIQGDMTSVVKDVTTGTWNYMSPECIISGGSNFQGHKINQKSDVWSLGCILYSLIYGKTPY------SHLTNTWQKLQAIAVSKQNIIFPKQSKLFPHGIPPVLMQTMELCLIKDVKTRPNVTDLLKLI 585
[Close]
BLAST of Kinase-like domain-containing protein vs. TrEMBL
Match: A0A1X2H778 (Kinase-like domain-containing protein OS=Syncephalastrum racemosum OX=13706 GN=BCR43DRAFT_319189 PE=3 SV=1)

HSP 1 Score: 140.198 bits (352), Expect = 2.384e-32
Identity = 92/279 (32.97%), Postives = 144/279 (51.61%), Query Frame = 2 
Query: 1472 IGEGGMSKVYSAIGKHDRQTYAVKVIVFEN--NLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEK--QPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL-------SGKSEFE-PKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPD----------SKKLTPLLRQIMDMCLVYEFKQRPSVEELLK 2242
            +G GG S+VY  +    R+ +A+K I   N      K    EIK++  +   +  IRL D      G  +++E  + D+   + ++  +    PDFI  YW  ML  V A+H ++I H DLK  NF++     IKLIDFGI++ +S DT+ I   E  GT  +MSPE +       +GKS  +  +  DVW++G +LY ++Y F P F+  N VY         Q++ + ++ I  P+          ++++TP L  +M  CL  E KQR S+ +LLK
Sbjct:   52 VGYGGTSRVYKILSHSRREIFALKRIKLANVDERAKKGYLNEIKLLHSLRDHSQIIRLFDYEYSSAGIDMILEYGEIDLAHLMHQQLMKQKFDPDFIRLYWKQMLHAVDAIHQQKIVHSDLKPANFLLVRGA-IKLIDFGIAKAISNDTTNIHREEQVGTLSYMSPEAIIVDNNITNGKSMIKLGRASDVWSLGCILYQMVYGFTP-FQELN-VYQKL------QIIPDAKHPIHYPEHVLPKKNKDPTERVTPELLDVMQSCLSREPKQRLSIPDLLK 321
[Close]
BLAST of Kinase-like domain-containing protein vs. TrEMBL
Match: A0A016T210 (Protein kinase domain-containing protein OS=Ancylostoma ceylanicum OX=53326 GN=Acey_s0147.g2602 PE=4 SV=1)

HSP 1 Score: 141.354 bits (355), Expect = 1.244e-31
Identity = 86/271 (31.73%), Postives = 148/271 (54.61%), Query Frame = 2 
Query: 1451 SYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVI-VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLI--GDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL---SGKSEFE-PKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLK 2242
            SY    ++G+GG S+V+    +   +  A+KV+ + E+ +V +    EI+++  +  + Y IR+I+  +   +    +VMEK   D+ TF++ ++ +I   FI  +W  MLRCVK +HD++I H DLK  NF++ +   +KLIDFGI+  +  D +        GT  +M+PE+L   SG  +++ P K DVW++G +LY ++Y   P F   ++     +       + +  Y I  PD  +  PLL  +M  CLV + + R  + ELL+
Sbjct:  185 SYIWLNVLGKGGSSRVFEVFDESRSEVCAMKVVDLGEDPVVRRCYLNEIELLKSLQGSPYVIRMIEYELRESENTLYVVMEKGDIDLATFLKTRRTEIDSAFIKYHWNEMLRCVKVIHDRKIVHSDLKPANFLLVKGS-LKLIDFGIAAGIPNDMTAAIKESQMGTLSYMAPEVLQGTSGDGKYKIPLKADVWSLGCILYNIVYGHLP-FPMKSQAAKMVA-------IVSDDYVIDFPDCHE--PLLVDVMKRCLVRDVRNRADINELLE 444
[Close]
BLAST of Kinase-like domain-containing protein vs. TrEMBL
Match: J9JXK6 (Protein kinase domain-containing protein OS=Acyrthosiphon pisum OX=7029 GN=100164108 PE=4 SV=2)

HSP 1 Score: 140.198 bits (352), Expect = 4.591e-31
Identity = 96/279 (34.41%), Postives = 149/279 (53.41%), Query Frame = 2 
Query: 1451 SYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFEN--NLVMKDVETEIKIMTIMSSTNYAIRLIDS--LIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL-SGKSEFEP----KKCDVWAMGIVLYTLIYNFQPRFKSGN---KVYA-STSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLI 2248
            +Y     +G GG S VY  +     Q  A+K +      +++ K    E+ ++  + S    IRL DS     DK   +VMEK   D+   I+  +  +S   I+ YW+ ML  V  +H K + H DLK  NF++  S R+KLIDFGI+ ++  D + +    ++GT+ +MSPE + SG S F+     +K DVW++G +LY+LIY   P     N   K+ A + S QN S L  +K +      ++ + P+L Q M +CL+ + K RP+V +LLKLI
Sbjct:  308 NYNILNTLGHGGSSIVYEVLHPDTNQVVAIKKVDLSEVEDIIAKGYLNEVNLLQNLQSCESVIRLFDSQYTTKDKILYMVMEKGDTDLSKLIRNTK-HMSVHMIMYYWSEMLITVNEIHAKGVIHSDLKPANFLLV-SGRLKLIDFGIASKIQGDMTSVLKDVTTGTWNYMSPECIRSGGSNFQGHKINQKSDVWSLGCILYSLIYGKTPYSHLTNTWQKLQAIAESTQNISFLSHSKTF------TQGIPPVLMQTMKLCLIKDVKARPNVVDLLKLI 578
[Close]
BLAST of Kinase-like domain-containing protein vs. TrEMBL
Match: A0A2A6CAV3 (Mrpl-4 OS=Pristionchus pacificus OX=54126 GN=PRIPAC_40532 PE=4 SV=1)

HSP 1 Score: 140.969 bits (354), Expect = 1.147e-30
Identity = 88/275 (32.00%), Postives = 153/275 (55.64%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENN--LVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLD-TSLISDGESSGTFIFMSPELLS--------GKSEFE-PKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLK 2242
            Y     IG+GG S+VY A       T A+KV+   +      +    E++++  +  + Y I+L D  + +   V+VMEK + D+ ++++ ++ + +P F+  +W AML+ V+ +HD ++ H+DLK  NF++  ++ +KLIDFGI+  +  D TSL+ D +  GT  +MSPE LS        G+S+F+   K DVW++G +LYT++Y  +P  +  N      + Q+ S  +       + P      P++  ++  CLVY+ K+R SV ELL+
Sbjct:  600 YAILNQIGKGGSSQVYKAFDDITGDTVAIKVVDLSDTDPSSREAFINEVELLDKLQGSRYVIKLFDYEVDENQLVVVMEKGEQDLGSYLKNRRMETTPTFLKYWWEAMLQAVQFVHDHKVVHMDLKPANFLLVSAD-LKLIDFGIASSIPSDKTSLLKDTQ-MGTLSYMSPESLSAAENDEEEGESKFKVTAKSDVWSLGCILYTMVYGKRPFDQFKNTRAKMGAIQDPSTRIH------YDPTDD---PMIVDVLKRCLVYDVKKRASVAELLE 863
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Cavefish
Match: ttk (ttk protein kinase [Source:NCBI gene;Acc:317763])

HSP 1 Score: 105.916 bits (263), Expect = 5.488e-23
Identity = 87/277 (31.41%), Postives = 136/277 (49.10%), Query Frame = 2 
Query: 1466 KLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVET------EIKIMT-IMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLD-TSLISDGESSGTFIFMSPELL------SGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQ-----IMDMCLVYEFKQRPSVEELL 2239
            K+IG GG SKVY  +  H +Q YAVK +    NL   D +T      EI+ +  +   ++  I+L D  I D    ++ME    D+ T+++ ++   S +    YW  ML  V+ +H   I H DLK  NFV+  +  +KLIDFGI+  +  D TS++ D +  GT  +M PE +       GK +  PK  DVW++G +LY +              Y  T  Q  +  +T K ++I  P  +   P + +     ++  CL+   K+R S+ ELL
Sbjct:  588 KMIGRGGSSKVYQVLD-HKKQLYAVKYV----NLDEADTQTIESYKNEIEHLNHLQQYSDQIIKLYDYEITDSYIYMLMECGSLDLNTWLRNRKTVNSLERKF-YWRNMLEAVQTIHKHGIVHSDLKPANFVIVNAS-LKLIDFGIANHIQPDMTSVVKDSQ-MGTLNYMPPEAIKDTSSKGGKPKISPKG-DVWSLGCILYCM-------------TYGKTPFQTITNQMT-KLHAIIDPSHEIDFPDIPEKDLLDVLKRCLIRNPKERISIAELL 841
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Cavefish
Match: tssk6 (testis-specific serine kinase 6 [Source:ZFIN;Acc:ZDB-GENE-060216-3])

HSP 1 Score: 85.1149 bits (209), Expect = 7.843e-18
Identity = 68/241 (28.22%), Postives = 117/241 (48.55%), Query Frame = 2 
Query: 1445 FGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFEN---NLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAV-IVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQP-----------------RFKSGNKVYASTSCQNF 2104
            FG Y   + +GEGG   V  A  +   Q  A+K++   N   +   K +  E+ I+   +   + I +++      G V IVME A+ D+++ I E  P +  +    ++T +L  ++ LH + I H DLKL N ++T   ++KL DFG+ R  S     +S     GT  + +PE+   +  ++PKK DVW++G++ Y ++    P                 +F +G KV  S  C++F
Sbjct:   13 FG-YSVVRDLGEGGYGMVKLATSERHSQQVAIKIMDRRNESSDFNTKLLPRELAILK-RARHPHIIEVLECFEMRDGLVFIVMEAAEMDLRSKILELYPGVPINQAKIWFTQLLSAMQYLHQQNIVHRDLKLLNVLLTADGQVKLTDFGLGR-FSRGFPFLSR-SYCGTRRYAAPEVNINRP-YDPKKADVWSLGVIFYAMVTGTTPFNEQEHCSLTDVQREPLKFPAGVKV--SGPCRDF 246
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000054199.1 (testis-specific serine/threonine-protein kinase 6-like [Source:NCBI gene;Acc:103028583])

HSP 1 Score: 82.4185 bits (202), Expect = 1.434e-16
Identity = 73/270 (27.04%), Postives = 129/270 (47.78%), Query Frame = 2 
Query: 1451 SYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSL-IGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISLQ 2257
             YE  + +  G  S V  A  K  ++T A+K++  +     K V+ E+ I+  +    + I ++D   +  +   IVME A  D++   ++ Q  I  D    +++ ++  V  LH + I+H DLK +N ++T   ++KLIDFG  R       L    E   T  + +PE+L  K  ++PKK DVW++G++LY ++    P              QN+      +R  I+ P+  +L    R ++   L Y +  RPS +++ +   LQ
Sbjct:   11 GYEVLRDLDGGDFSTVKLAKSKKYQKTVALKIMQID-----KHVQKEVSILKRVKHP-HIISVLDIFEMAGRLVCIVMEAAPSDLEK-AKKFQSVIPTDQARTWFSQLVSAVVYLHKQNIAHRDLKCENVLLTADNQVKLIDFGFGRFSRGFPDLTR--EFCCTPAYAAPEVLL-KRPYDPKKADVWSLGVILYWMVVGRLP-------------FQNWFDFPGCQRKPIYFPE--RLEEPCRDLISYMLRYNYLMRPSAKKVAQHPWLQ 255
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Cavefish
Match: nuak1a (NUAK family kinase 1 [Source:NCBI gene;Acc:103029612])

HSP 1 Score: 84.3445 bits (207), Expect = 1.685e-16
Identity = 63/210 (30.00%), Postives = 107/210 (50.95%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE---NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKA-KCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGN 2071
            YE  + +G G   KV  A+ KH  +  A+K I  E       M  +  EI+IM+ +    + I + +        VIVME A K ++  +I E++  +S      ++  ++  V   H   + H DLKL+N ++ ++  IK+ DFG+S     D  L +     G+ ++ SPE+++G+    P + D WA+G++LYTL+Y   P F  G+
Sbjct:   51 YELLETLGRGTYGKVKKAVEKHTGRVVAIKSIRKEKIKEEQDMVHIRREIEIMSSLRHP-HIISIYEVFENKDKIVIVMEYASKGELYDYISERR-KLSERETRHFFRQIVSAVHHCHKNGVVHRDLKLENVLLDDNCNIKIADFGLSNLYQKDKLLQT---FCGSPLYASPEIVNGRPYRGP-EVDSWALGVLLYTLVYGTMP-FDGGD 253
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Cavefish
Match: pdpk1b (3-phosphoinositide-dependent protein kinase 1 [Source:NCBI gene;Acc:103033547])

HSP 1 Score: 83.9593 bits (206), Expect = 1.781e-16
Identity = 61/210 (29.05%), Postives = 113/210 (53.81%), Query Frame = 2 
Query: 1466 KLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKD-----VETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAK-CDMKTFIQEKQPDISPDFILKYWTAMLRC-VKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNK 2074
            K++GEG  S V  A      + YA+K++  E   +MK+     V+ E  +M+I+    + ++L  +   ++     +  AK  ++  +I  ++     +   ++++A + C ++ LH K I H DLK +N +++E   I++ DFG ++QLS D+         GT  ++SPELL+ KS    K  D+WA+G ++Y L+    P F++GN+
Sbjct:   64 KILGEGSFSTVVLAKEHSTGKEYAIKIL--EKRHIMKENKAQYVKRERDVMSILDHP-FFVKLYFTFQDEEKLYFGLSYAKNGELLKYI--RKIGSFDETCTRFYSAEIVCALEYLHQKGIIHRDLKPENILLSEEMHIQITDFGTAKQLSSDSRQARANSFVGTAQYVSPELLTEKSAC--KSSDLWALGCIIYQLVAGLPP-FRAGNE 265
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Sea Lamprey
Match: STK36 (serine/threonine kinase 36 [Source:HGNC Symbol;Acc:HGNC:17209])

HSP 1 Score: 91.6633 bits (226), Expect = 3.390e-19
Identity = 59/204 (28.92%), Postives = 108/204 (52.94%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVI--VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRF 2059
            Y   ++IGEG   KVY    ++  Q  A+K I  V  ++  ++++  EI IM  +   N  ++++DS   DK  V+V + A+ ++   + E   ++  + + +    ++  +  LH  RI H D+K QN ++ +   +KL DFG +R +S++T +++     GT ++MSPEL+  K        D+W+MG +LY L     P +
Sbjct:    4 YHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNI-VQMLDSFETDKEVVVVTDYAEGELFQIL-EDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTS--IKGTPLYMSPELVEEKP--YDHTADLWSMGCILYELFVGTPPFY 201
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Sea Lamprey
Match: tssk6 (testis-specific serine kinase 6 [Source:ZFIN;Acc:ZDB-GENE-060216-3])

HSP 1 Score: 81.6481 bits (200), Expect = 2.468e-17
Identity = 54/205 (26.34%), Postives = 101/205 (49.27%), Query Frame = 2 
Query: 1451 SYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVI---VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAV-IVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQP 2053
             Y     +GEG  SKV  A  +   +  A+KVI       +   K +  E+ ++  +   N  + ++  + G +G + IVME A+ D+   +QE+   +        +T +   V  LH   +SH D+K +N ++ +   ++L DFG +RQL             G+  + SPE+L G + ++P+  D+W++G+VL+ ++  + P
Sbjct:   11 GYRLGYTLGEGTYSKVKFATSEQHERRVAIKVIDRRKLPPDFEEKFLPREVDLLRSLHHQN-IVEVLQLIEGCRGYIFIVMELAQSDLLRLMQERG-SLDQRTARGIFTELCSAVHYLHQMHVSHRDVKCENVLLVDGLHVRLTDFGFARQLHPGCLEELSKTYCGSAAYTSPEVLLG-TPYDPRLLDLWSLGVVLFIMVTGYMP 212
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Sea Lamprey
Match: myo3a (myosin IIIA [Source:ZFIN;Acc:ZDB-GENE-041026-4])

HSP 1 Score: 83.9593 bits (206), Expect = 7.784e-17
Identity = 73/287 (25.44%), Postives = 134/287 (46.69%), Query Frame = 2 
Query: 1451 SYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNL------VMKDVETEIKIMTIMSSTNYAIRLI------DSLIGDKGAVI--------VMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFE---PKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLK 2242
            ++E  + IG+G   KVY A  + D    AVK +   NNL      + +++E E  I+T +      +R        D + GD+  ++        V +  K  +K    E+   +   +IL+     L  +  LH   I H D+K  N ++T    I+L+DFG+S Q+S   + +    + GT  +M+PE+++ + + +    ++CDVW+MGI    L     P       +Y     +   ++  N   ++ +P+     PL  + +  CLV +F++R +V +LL+
Sbjct:   23 TWELVETIGKGTYGKVYKATSRKDGSKAAVKTLDPVNNLETSNQDIDEEIEAEYSILTSLPEHPNIVRFFGMYYQKDGVNGDQLWIVLELCNGGSVTDLVKGQLKR--GERMDVMLIAYILR---GALLGLNHLHSHNIIHRDIKGNNILLTTDGGIRLVDFGVSAQVS--KTRVERNTAVGTPFWMAPEVIACEQQLDYMYDRRCDVWSMGITAIELGDGDPP-------LYELHPMRALFKIPRNPPPTLKQPEL--WPPLFNEFIAQCLVKDFERRATVSQLLE 293
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Sea Lamprey
Match: MARK3 (microtubule affinity regulating kinase 3 [Source:HGNC Symbol;Acc:HGNC:6897])

HSP 1 Score: 81.2629 bits (199), Expect = 3.815e-16
Identity = 75/267 (28.09%), Postives = 124/267 (46.44%), Query Frame = 2 
Query: 1448 GSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVI--VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCD-----MKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQP--------------RFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIM 2185
            G+Y   K IG+G  +KV  A      +  AVK+I     N   ++ +  E++IM I++  N  ++L + +  +K   +VME A        +    + K+ +    F       ++  V+  H K I H DLK +N ++     IK+ DFG S + +L + L +     G+  + +PEL  GK +++  + DVW++G++LYTL+    P              R K     Y ST C+N   LL  KR+ +  P  +     L QIM
Sbjct:   52 GTYRLLKTIGKGNFAKVKLARHTLTGREVAVKIIDKTQLNPSSLQKLFREVRIMKILNHPNI-VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKF-----RQIVSAVQYCHQKHIVHRDLKAENLLLDADMNIKIADFGFSNEFTLGSKLDT---FCGSPPYAAPELFQGK-KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEN---LL--KRFLVLNPAKRG---SLEQIM 300
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Sea Lamprey
Match: MARK3 (microtubule affinity regulating kinase 3 [Source:HGNC Symbol;Acc:HGNC:6897])

HSP 1 Score: 80.1073 bits (196), Expect = 4.684e-16
Identity = 70/254 (27.56%), Postives = 119/254 (46.85%), Query Frame = 2 
Query: 1448 GSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVI--VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCD-----MKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQP--------------RFKSGNKVYASTSCQNFSQLLTNKRYSIFKP 2146
            G+Y   K IG+G  +KV  A      Q  AVK+I     N   ++ +  E++IM +++  N  ++L + +  +K   +VME +        +    + K+ +    F       ++  V+  H K I H DLK +N ++     IK+ DFG S + +L + L +     G+  + +PEL  GK +++  + DVW++G++LYTL+    P              R K     Y ST C+N   LL  KR+ +  P
Sbjct:   66 GNYRLLKTIGKGNFAKVKLAKHTLTGQEVAVKIIDKTQLNTSSLQKLFREVRIMKVLNHPNI-VKLFEVIEMEKTLYLVMEYSSGGEVFDYLVAHGRMKEKEARAKF-----RQIVSAVQYCHQKHIVHRDLKAENLLLDADMNIKIADFGFSNEFTLGSKLDT---FCGSPPYAAPELFQGK-KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEN---LL--KRFLVLHP 304
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Yeast
Match: MPS1 (Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186])

HSP 1 Score: 100.523 bits (249), Expect = 2.555e-22
Identity = 80/288 (27.78%), Postives = 138/288 (47.92%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQP-DISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL-------SGKSEFEPKK------CDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPD----SKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISLQ 2257
            YE  +L+G GG S+VY   G  +R  YA+K + F+  ++  +   + EI+++  +      I+L+D  +GD    ++ME    D+   + ++    +  +F+  Y   ML C+K +HD  I H DLK  NFV+ +   +K+IDFGI+  +   T  I      GT  +M+PE L       + +++ E  K       D+W+ G ++Y +IY   P        Y S   QN    + N    I  P+    ++K+     ++M  CL     +R +V+++L    LQ
Sbjct:  440 YEKIELLGRGGSSRVYKVKGSGNR-VYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKRVIQLLDYEMGDGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKG-ILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPP--------YGSFQGQNRLLAIMNPDVKIPFPEHTSNNEKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQ 717
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072])

HSP 1 Score: 88.9669 bits (219), Expect = 1.423e-18
Identity = 65/264 (24.62%), Postives = 122/264 (46.21%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEK-AKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLK 2242
            Y  +++IG G    VY AI KH  Q  A+K +V+EN+  + D+  EI ++  ++  N  ++    +       I++E  A   ++  I      +S +    Y T  L  +K LH + + H D+K  N +++    +KL DFG+S  ++     +     +GT  +M+PE+L  +        D+W++G  +  ++        + N  Y + +  N    + N  Y  + P S   +  L+  +  C V    +RP+ ++LLK
Sbjct:   25 YHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNN-IVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTL-----AGTLNWMAPEILGNRG--ASTLSDIWSLGATVVEML--------TKNPPYHNLTDANIYYAVENDTY--YPPSS--FSEPLKDFLSKCFVKNMYKRPTADQLLK 268
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144])

HSP 1 Score: 83.1889 bits (204), Expect = 7.505e-17
Identity = 64/265 (24.15%), Postives = 127/265 (47.92%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNL-VMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEK-AKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLK 2242
            ++  ++IG G    VY        + YA+KV+  +++   ++DV+ EI+ +  +   +   R   S + D    I+ME  A   +++ ++  +  I   +I      +L  +K +H   + H D+K  N ++T    +KL DFG++ Q++  TSL      +GT  +M+PE++     ++  K D+W++GI  Y +         +GN  Y         QL+   +      + +  +  L++ + +CL  + K+R S ++LLK
Sbjct:   23 FKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGK--IDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVN-QTSLRRQ-TMAGTPYWMAPEVIMEGVYYD-TKVDIWSLGITTYEIA--------TGNPPYCDVEALRAMQLIIKSKPPRL--EDRSYSTSLKEFIALCLDEDPKERLSADDLLK 272
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Yeast
Match: CDC5 (Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603])

HSP 1 Score: 82.4185 bits (202), Expect = 1.082e-16
Identity = 65/273 (23.81%), Postives = 131/273 (47.99%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIV---FENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSG--NKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISLQ 2257
            Y     +GEGG ++ +  I     + +A K +     ++    K + +EI+I   MS  N  ++ ID    D    I++E         + +++  ++   +  + T +   +K +H +R+ H DLKL N     +  +K+ DFG++  L+ ++         GT  +++PE+L GK      + D+W++G++LY L+   +P F++   N +Y    C++FS       +   KP S +   L+R I+ +  +    +RPS+ E++  +  +
Sbjct:   82 YHRGHFLGEGGFARCFQ-IKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPN-IVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESE--RKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIG-KPPFQARDVNTIYERIKCRDFS-------FPRDKPISDEGKILIRDILSLDPI----ERPSLTEIMDYVWFR 338
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Yeast
Match: SNF1 (AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885])

HSP 1 Score: 80.1073 bits (196), Expect = 4.414e-16
Identity = 55/204 (26.96%), Postives = 106/204 (51.96%), Query Frame = 2 
Query: 1448 GSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVI---VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGE----SSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLI 2038
            G+Y+  K +GEG   KV  A      Q  A+K+I   V   + +   +E EI  + ++    + I+L D +      ++V+E A  ++  +I ++   +S     +++  ++  V+  H  +I H DLK +N ++ E   +K+ DFG+S       ++++DG     S G+  + +PE++SGK    P + DVW+ G++LY ++
Sbjct:   53 GNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHP-HIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRD-KMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLS-------NIMTDGNFLKTSCGSPNYAAPEVISGKLYAGP-EVDVWSCGVILYVML 246
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Nematostella
Match: EDO30752 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZW1])

HSP 1 Score: 96.2857 bits (238), Expect = 3.979e-22
Identity = 71/259 (27.41%), Postives = 128/259 (49.42%), Query Frame = 2 
Query: 1535 AVKVIVFEN--NLVMKDVETEIKIMTIMSSTNYAIRLIDSLIG--DKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL---------SGKSEFEP-----KKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISLQ 2257
            AVK +  E+  +++++    EI ++  +   ++ I+L +  +   +K  ++V+E    D+ TF+++ +  +S   +  YW  MLR V  +H++ I H DLK  NF+  + + +KLIDFGI+  +  D + I      GT  FM+PE             +S  +P     +  DVW++G +LY ++Y   P     N+           Q + +  Y+I  PD +  T LL  +M  CL    ++R ++++LL    LQ
Sbjct:    3 AVKQVSLEDADDVIIESYINEITLLNQLQGCDHIIKLYNWELNKEEKTILLVLEAGTMDLSTFLRKNRGCLSSTHLAVYWEQMLRAVNVIHERGIVHSDLKPANFLFVDVQ-LKLIDFGIANAIQGDQTSIQRDTQIGTLNFMAPEAFLDVSNAHHSHQRSGAKPCMKIGRASDVWSLGCILYNMVYGRTPFQHITNQAMK-------LQCIIDPNYAIEFPDIQN-THLL-DVMKGCLARNPRERYTIQQLLNHPFLQ 251
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Nematostella
Match: EDO49138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH03])

HSP 1 Score: 88.1965 bits (217), Expect = 2.374e-19
Identity = 73/275 (26.55%), Postives = 128/275 (46.55%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVE-----TEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKC-DMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEP--KKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISL 2254
            Y+   +IG+G     +    +  ++ YA+K +   N   M   +      E+KI++ +   N  +R  D+        IVME A+  D+ T I++     S + IL +   +L  +K +H + I H DLK QN  +T+ + +K+ DFGI+R   LD++      + GT  ++SPE+     + +P   K D+WA+G VLY L     P            +  N + L+    +  + P  +   PLL  ++ + L      RPS ++L+ +  L
Sbjct:    4 YQKIDIIGKGTFGSAWLVESRQSKRLYALKEL---NATAMPSEDRHLALNEVKILSTLKHRN-IVRYRDAFEETGRFYIVMEYAEGGDLHTKIKQAVEPFSSERILNWLAQLLLALKHIHGQNILHRDLKTQNIFLTKDDVVKIGDFGIAR--ILDSTCDHARTTVGTPYYLSPEI----CQRQPYNNKSDIWALGCVLYELTTRTHP-----------FTADNLTNLVVKILHGNYPPIPRFYGPLLEDLVAVMLKINPADRPSAKQLIYVPGL 257
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Nematostella
Match: EDO49090 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI47])

HSP 1 Score: 79.7221 bits (195), Expect = 1.170e-16
Identity = 67/213 (31.46%), Postives = 108/213 (50.70%), Query Frame = 2 
Query: 1439 ILFGS----YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVME-KAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTE---SERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQP 2053
            I +GS    Y+  + IG+G    V   + K   QTYA KV+   N+ + K+   EI++M  + S    + LID+       V+++E     ++   I E+   +  D I  Y   +L  +  +H   I HLDLK +N +M E   S +IKL+DFG++R+L  D  + S   S GT  F++PE++  K        D+W++G+V Y L+    P
Sbjct:    3 IKYGSADEFYDMNEEIGKGAYGIVKKCVDKATGQTYAAKVVTTSNSNLRKETMREIEVMRKLGSHKKLVGLIDAYHTPFEIVMILEFIPGGELFERIIEEDYLMEEDAIY-YVHQVLLALDYMHGNNIVHLDLKPEN-IMCESINSNQIKLVDFGLARELKKDEEVKS---SFGTPDFVAPEVIRMKP--VSTASDMWSLGVVTYVLLSGLMP 208
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Nematostella
Match: EDO46185 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQY7])

HSP 1 Score: 81.2629 bits (199), Expect = 7.589e-16
Identity = 76/268 (28.36%), Postives = 131/268 (48.88%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCD-MKTFIQEKQPDI-SPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERI-KLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQ-IMDMCLVYEFKQRPSVEELL 2239
            YE  +++G G    VY      D     +K I  E       +    E+K++++    N  IR  DS + +K  +IVME A+   +  ++Q++   +   D IL+ +  +L  ++ +H  +I H DLK QN ++ +  ++ K+ DFGIS+ LS   S        G+  ++SPEL  GK     +K DVW++G VLY L    +  F++           N   L+       F P  ++ +  LR+ I+DM LV +  +RP ++E++
Sbjct:    4 YEKVRIVGRGAYGTVYLCRRLVDNFLVIIKQIPVEEMTKEERQSALNEVKVLSMFQHPNI-IRYYDSFVQEKALMIVMEYAQGGTIYDYLQQRGGKLMDEDEILRLFVQILLALRHVHKGQILHRDLKTQNILLNKKRKVVKIGDFGISKILS---SKSKANTVIGSPCYISPELCEGKPY--NQKSDVWSLGCVLYELT-TLKRAFEA----------SNLPALVLKIMRGYFSPIPERYSEELRKLILDM-LVLDPTKRPGIKEIM 253
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Nematostella
Match: EDO41242 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z6])

HSP 1 Score: 77.0258 bits (188), Expect = 1.244e-15
Identity = 58/220 (26.36%), Postives = 106/220 (48.18%), Query Frame = 2 
Query: 1451 SYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCD-------MKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESER---IKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEP--KKCDVWAMGIVLYTLIYNFQPRFKSGNK 2074
            +Y+  +LIGEG  +KV+  I +     +A K +   +    + +E EI +   +   N  + L  S+   +   ++ME             +T+  EKQ  +           +L  ++ LH +RI H D+K  N ++  +     IKL DFG+++ L  DT +IS G +SG  +F++PE +      EP  +  D+WA G++ Y L+  + P + + ++
Sbjct:    4 NYDMLELIGEGSFAKVFRCIERKTGLEFAAKELRLTDVEDKEKIEQEIAVWKDLRHENI-VSLYSSIREGETVCLIMEYVAGGSLFDEVIQQTYYSEKQARLVT-------RQLLNALEYLHSRRIVHRDIKPDNLLLKRTGNNVTIKLADFGLAQALPNDTDVISCG-ASGAPMFLAPETVLE----EPIGRAVDIWACGVIFYLLLVGYPPFWSNSDE 210
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Medaka
Match: ttk (TTK protein kinase [Source:NCBI gene;Acc:101155587])

HSP 1 Score: 106.686 bits (265), Expect = 3.180e-23
Identity = 105/371 (28.30%), Postives = 176/371 (47.44%), Query Frame = 2 
Query: 1208 SYQTPLKSHKKNMLKTPKKTAMNNISSYIISPIVKFQGNIDSSYVDDNVDI---EASIILNYDVDSQID--NIINLTERTSKILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE--NNLVMKDVETEIKIMTIMSS-TNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELL------SGK--SEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLL--RQIMDM---CLVYEFKQRPSVEELLKLISLQ 2257
            S Q P + +  +  +TP      N +S++ +P+VK    + SS V  +      ++   LN     Q    ++ +L+  +  I    +   K+IG GG SKV+  +  H +Q +AVK +  E  +   ++  + EI+ +  +   ++  I+L D  I +    ++ME    D+ T+++ ++  ++P     YW  ML  V  +H   I H DLK  NFV+  +  +KLIDFGI+ ++  D + I      GT  +M PE +      SGK  S+  PK  DVW++G +LY + Y   P F+S     A             K ++I  P  K   P +  R ++D+   CLV   ++R S+ ELL    LQ
Sbjct:  582 SLQRPSRLNPHSFCQTPCSNQNPNPNSFV-TPVVKGGPEVWSSAVAAHRTRALQQSHTPLNPAASFQTPQASLSSLSNESITIKGKQFFVLKIIGRGGSSKVFQVL-DHKKQLFAVKYVDLEEADAQTVESYKNEIEHLNHLQQYSDQIIKLYDYEITNSYIYMLMECGNLDLNTWLRNRKSVVNPLERKFYWKNMLEAVHTIHKHGIIHSDLKPANFVIVNAS-LKLIDFGIANRIQPDVTSIMKDSQVGTLNYMPPEAIKDTSSQSGKARSKISPKG-DVWSLGCILYCMTYGKTP-FQSITNQMA-------------KLHAIIDPSHKIEFPDISERDLLDVLKRCLVRNPRERISIVELLDHPYLQ 934
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Medaka
Match: nek6 (NIMA related kinase 6 [Source:NCBI gene;Acc:101173323])

HSP 1 Score: 95.1301 bits (235), Expect = 5.167e-21
Identity = 78/274 (28.47%), Postives = 136/274 (49.64%), Query Frame = 2 
Query: 1448 GSYECQKLIGEGGMSKVYSAIGKHDRQTYAVK-VIVFE--NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKC----DMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKS-EFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKL 2245
             ++  ++ IG G  S+VY A+   DRQ+ A+K V +FE  +    +D   EI ++  ++  N  I+ +DS I D    IV+E A       M  + ++K+  I    I KY+  +   ++ +H +R+ H D+K  N  +T +  +KL D G+ R  S  T+  +     GT  +MSPE +      F   K D+W++G +LY +     P +  G+K+   + C+   Q      Y    PD  + +  LR+++ MC+  E  QRP +  +L++
Sbjct:   39 ANFRVERKIGRGQFSEVYRAVRLLDRQSVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPN-IIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKKRRLIPERTIWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGEVKLGDLGLGRFFSSKTT--AAHSLVGTPYYMSPERIHENGYNF---KSDIWSLGCLLYEMAALQSPFY--GDKMNLLSLCRKIEQC----DYPPLPPD--QYSDKLRELVSMCINSEPDQRPDIIFVLQI 298
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Medaka
Match: nuak1b (NUAK family kinase 1 [Source:NCBI gene;Acc:101169694])

HSP 1 Score: 88.1965 bits (217), Expect = 1.268e-17
Identity = 64/210 (30.48%), Postives = 109/210 (51.90%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFE---NNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKA-KCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGN 2071
            YE  + +G G   KV  AI +H  +  A+K I  E   +   M  +  EI+IM+ +    + I + +        VIVME A K ++  +I E++  +S     +++  ++  V   H   + H DLKL+N ++ E+  IK+ DFG+S     D  L +     G+ ++ SPE+++G+    P + D WA+G++LYTL+Y   P F  G+
Sbjct:   64 YELLETLGRGTYGKVKKAIERHSGREVAIKSIRKEKIKDEQDMVHIRREIEIMSSLRHP-HIISIYEVFENKDKIVIVMEYACKGELYDYISERR-RLSERETRRFFRQIVSAVHHCHKNGVVHRDLKLENVLLDENGNIKIADFGLSNLYHKDKLLQT---FCGSPLYASPEIVNGRPYRGP-EVDSWALGVLLYTLVYGTMP-FDGGD 266
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Medaka
Match: si:ch211-117c9.1 (NUAK family SNF1-like kinase 1 [Source:NCBI gene;Acc:101166457])

HSP 1 Score: 87.8113 bits (216), Expect = 1.441e-17
Identity = 71/267 (26.59%), Postives = 127/267 (47.57%), Query Frame = 2 
Query: 1454 YECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIV---FENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKA-KCDMKTFIQEKQ--PDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEEL 2236
            YE  + +G+G   KV  A+ +   +T A+K I      ++L    ++ EI+I + +   N  IR  +        VIVME A + ++  +IQE++  P+     I +  T+    V   H   + H DLKL+N ++ +   +KL DFG+S      + L +     G+ ++ SPE++ G     P + D WA+G++LYTL+Y+  P        +  TS    +  ++  RY    P S   +     ++D  L    + R ++E++
Sbjct:   71 YEVMETLGKGTYGKVKKAVERASLRTVAIKSIRKDRITDDLERIHIQREIEITSSLCHPNI-IRFHEVFESRDKIVIVMEFASRGELYDYIQERRRLPEAEARSIFRQITSA---VHYCHKNGVVHRDLKLENILLDQDLNVKLADFGLSNNFHRGSLLQT---YCGSPLYASPEIVKGLPYVGP-EVDCWALGVLLYTLVYSSMP--------FDGTSHAKLTDQISQGRYHRANPPSDACS-----LIDWLLTVRVEDRATIEDV 316
[Close]
BLAST of Kinase-like domain-containing protein vs. Ensembl Medaka
Match: nek7 (NIMA related kinase 7 [Source:NCBI gene;Acc:101170580])

HSP 1 Score: 79.337 bits (194), Expect = 1.072e-15
Identity = 73/269 (27.14%), Postives = 125/269 (46.47%), Query Frame = 2 
Query: 1445 FGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNY--AIRLIDSLIGDKGAVIVMEKAKCD----MKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKS-EFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKP-DSKKLTPLLRQIMDMCLVYEFKQRPSV 2227
              +++ +K IG+G  S+VY A    D    A+K I   N +  K  +  IK + ++   N+   I+   S I D    IV+E A       M    + ++  I    + KY+  + R ++ +H +R+ H D+K  N  +T +  +KL D G+ R  S  T+  +     GT  +MSPE L      F   K D+W++G +LY +     P +  G+K+       N   L T  +   + P  S   +  LR ++DMC+  + ++RP +
Sbjct:   32 LANFQIEKKIGKGQFSEVYRARYILDNTPVALKKIQIFNLMDAKARQDCIKEIDLLKQLNHPNVIKYHASFIEDNELNIVLELADAGDLSRMINHFKNQRRLIPEKAVWKYFVQVCRALEHMHSRRVMHRDIKPANVFVTATGVVKLGDLGLGRFFSSKTT--AAHSLVGTPYYMSPERLRENGYNF---KSDIWSLGCLLYEMAALQSPFY--GDKM-------NLYSLCTKIQQCDYPPLPSDHYSQELRDLVDMCINPDPEKRPDI 286
[Close]
BLAST of Kinase-like domain-containing protein vs. Planmine SMEST
Match: SMESG000044282.1 (SMESG000044282.1)

HSP 1 Score: 1342.41 bits (3473), Expect = 0.000e+0
Identity = 683/686 (99.56%), Postives = 685/686 (99.85%), Query Frame = 2 
Query:  200 MEKYIKEFQDFIKFSLRTIDDLTYYLNASKHYKEVDLLVETIEEIMVNDTLDNRFELFLRIYETLSLVLTEPPDAYLKYKFRYFIMNWQVDSSEAIFNLNLIIKEINVYNDQLISAVAFYKLVFVSKDEALQFLRQPFQCTEVFLKRIISMVTENDYYSLINRMGEYWYFPVIKQNDKCMELIQKIQSRTLNVKKVEFIINCTVSSDIPXXXXXXXXXXXXYSPVPESPVLXXXXXXXXXXXXAHPLVKIEDSKDHTTIEGTQNQNIEINDPLCSSLDDSFMFLTIKNTNSDSTRKQTLDDNFDSSETTIQAKPHTSDTEDQLNDDILNQNIDPEYSYQTPLKSHKKNMLKTPKKTAMNNISSYIISPIVKFQGNIDSSYVDDNVDIEASIILNYDVDSQIDNIINLTERTSKILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISLQ 2257
            MEKYIKEFQDFIKFSLRTIDDLTYYLNASKHYKEVDLLVETIEEIMVNDTLDNRFELFLRIYETLSLVLTEPPDAYLKYKFRYFIMNWQVDSSEAIFNLNLIIKEINVYNDQLISAVAFYKLVFVSKDEALQFLRQPFQCTEVFLKRIISMVTENDYYSLINRMGEYWYFPVIKQNDKCMELIQKIQSRTLNVKKVEFIINCTVSSDIP+NITNTSNKNLNYSPVPESPVLNTISRTSNNNRRAHPLVKIEDSKDHTTIEGTQNQNIEINDPLCSSLDDSFMFLTIKNTNSDSTRKQTLDDNFDSSETTIQAKPHTS TEDQLNDDILNQNIDPEYSYQTPLKSHKKNMLKTPKKTAMNNISSYIISPIVKFQGNIDSSYVDDNVDIEASIILNYDVDSQIDNIINLTERTSKI+FGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISLQ
Sbjct:    1 MEKYIKEFQDFIKFSLRTIDDLTYYLNASKHYKEVDLLVETIEEIMVNDTLDNRFELFLRIYETLSLVLTEPPDAYLKYKFRYFIMNWQVDSSEAIFNLNLIIKEINVYNDQLISAVAFYKLVFVSKDEALQFLRQPFQCTEVFLKRIISMVTENDYYSLINRMGEYWYFPVIKQNDKCMELIQKIQSRTLNVKKVEFIINCTVSSDIPDNITNTSNKNLNYSPVPESPVLNTISRTSNNNRRAHPLVKIEDSKDHTTIEGTQNQNIEINDPLCSSLDDSFMFLTIKNTNSDSTRKQTLDDNFDSSETTIQAKPHTSYTEDQLNDDILNQNIDPEYSYQTPLKSHKKNMLKTPKKTAMNNISSYIISPIVKFQGNIDSSYVDDNVDIEASIILNYDVDSQIDNIINLTERTSKIVFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISLQ 686
[Close]
BLAST of Kinase-like domain-containing protein vs. Planmine SMEST
Match: SMESG000044282.1 (SMESG000044282.1)

HSP 1 Score: 1335.47 bits (3455), Expect = 0.000e+0
Identity = 677/680 (99.56%), Postives = 679/680 (99.85%), Query Frame = 2 
Query:  218 EFQDFIKFSLRTIDDLTYYLNASKHYKEVDLLVETIEEIMVNDTLDNRFELFLRIYETLSLVLTEPPDAYLKYKFRYFIMNWQVDSSEAIFNLNLIIKEINVYNDQLISAVAFYKLVFVSKDEALQFLRQPFQCTEVFLKRIISMVTENDYYSLINRMGEYWYFPVIKQNDKCMELIQKIQSRTLNVKKVEFIINCTVSSDIPXXXXXXXXXXXXYSPVPESPVLXXXXXXXXXXXXAHPLVKIEDSKDHTTIEGTQNQNIEINDPLCSSLDDSFMFLTIKNTNSDSTRKQTLDDNFDSSETTIQAKPHTSDTEDQLNDDILNQNIDPEYSYQTPLKSHKKNMLKTPKKTAMNNISSYIISPIVKFQGNIDSSYVDDNVDIEASIILNYDVDSQIDNIINLTERTSKILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISLQ 2257
            EFQDFIKFSLRTIDDLTYYLNASKHYKEVDLLVETIEEIMVNDTLDNRFELFLRIYETLSLVLTEPPDAYLKYKFRYFIMNWQVDSSEAIFNLNLIIKEINVYNDQLISAVAFYKLVFVSKDEALQFLRQPFQCTEVFLKRIISMVTENDYYSLINRMGEYWYFPVIKQNDKCMELIQKIQSRTLNVKKVEFIINCTVSSDIP+NITNTSNKNLNYSPVPESPVLNTISRTSNNNRRAHPLVKIEDSKDHTTIEGTQNQNIEINDPLCSSLDDSFMFLTIKNTNSDSTRKQTLDDNFDSSETTIQAKPHTS TEDQLNDDILNQNIDPEYSYQTPLKSHKKNMLKTPKKTAMNNISSYIISPIVKFQGNIDSSYVDDNVDIEASIILNYDVDSQIDNIINLTERTSKI+FGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISLQ
Sbjct:   89 EFQDFIKFSLRTIDDLTYYLNASKHYKEVDLLVETIEEIMVNDTLDNRFELFLRIYETLSLVLTEPPDAYLKYKFRYFIMNWQVDSSEAIFNLNLIIKEINVYNDQLISAVAFYKLVFVSKDEALQFLRQPFQCTEVFLKRIISMVTENDYYSLINRMGEYWYFPVIKQNDKCMELIQKIQSRTLNVKKVEFIINCTVSSDIPDNITNTSNKNLNYSPVPESPVLNTISRTSNNNRRAHPLVKIEDSKDHTTIEGTQNQNIEINDPLCSSLDDSFMFLTIKNTNSDSTRKQTLDDNFDSSETTIQAKPHTSYTEDQLNDDILNQNIDPEYSYQTPLKSHKKNMLKTPKKTAMNNISSYIISPIVKFQGNIDSSYVDDNVDIEASIILNYDVDSQIDNIINLTERTSKIVFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKCDVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPDSKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISLQ 768
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BLAST of Kinase-like domain-containing protein vs. Planmine SMEST
Match: SMESG000071238.1 (SMESG000071238.1)

HSP 1 Score: 429.869 bits (1104), Expect = 1.310e-144
Identity = 219/278 (78.78%), Postives = 232/278 (83.45%), Query Frame = 2 
Query: 1148 SDTEDQLNDDILNQNIDPEYSYQTPLKSHKKNMLKTPKKTAMNNISSYIISPIVKFQGNIDSSYVDDNVDIEASIILNYDVDSQIDNIINLTERTSKILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVIVFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTESERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSE 1981
            +DT+DQLNDDILNQNIDPEYSY+TPLKSHKKNM+KTPKKTAMNN SSYIISPIV+ QGN DSSYVDDNVDIEASIILNYDV+SQIDNIINLTERTSKI+FGSYE QKLIGE  MSK++                             +IKIMTIM  T Y IRLIDSLIGDKGAVIVMEKA CDMK FIQEKQPDISPDF+LKY TAMLRC KALHDKRISHLDLKLQNFVMTESERIKLIDFGI+RQLSLDTSLISDGESSGTFIF   +LLSGKSE
Sbjct:    3 NDTDDQLNDDILNQNIDPEYSYRTPLKSHKKNMVKTPKKTAMNNASSYIISPIVQLQGNTDSSYVDDNVDIEASIILNYDVNSQIDNIINLTERTSKIVFGSYESQKLIGEAAMSKMWK----------------------------QIKIMTIMFLTYYVIRLIDSLIGDKGAVIVMEKANCDMKIFIQEKQPDISPDFVLKYRTAMLRCGKALHDKRISHLDLKLQNFVMTESERIKLIDFGINRQLSLDTSLISDGESSGTFIFTIRKLLSGKSE 252
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BLAST of Kinase-like domain-containing protein vs. Planmine SMEST
Match: SMESG000008316.1 (SMESG000008316.1)

HSP 1 Score: 258.455 bits (659), Expect = 1.955e-81
Identity = 141/215 (65.58%), Postives = 153/215 (71.16%), Query Frame = 2 
Query: 1148 SDTEDQLNDDILNQNIDPEYSYQTPLKSHKKNMLKTPKKTAMNNISSYIISPIVKFQGNIDSSYVDDNVDIEASIILNYDVDSQIDNIINLTERTSKIL--FGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVI----VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCDMKTFIQEKQPDISPDFILKYWTAML 1774
            +DTEDQLNDDILNQNIDPEYSY+TPL SHKKNMLKTPKKTAMNN S YIIS                                    +I L+    ++L  F   ECQKLIGEG MSKVYS IGK D Q+YAVKVI    VFENNL MKD ETEIKIMTIMSSTNYAIRLIDSL+GDKGAVIVMEKAKCDMKTFIQE++ D SPDFI KY+TA+L
Sbjct:    3 NDTEDQLNDDILNQNIDPEYSYRTPLISHKKNMLKTPKKTAMNNASYYIIS--------------------------------YYSQLITLSTSQKELLKLFSGLECQKLIGEGEMSKVYSTIGKQDCQSYAVKVIEKVMVFENNLAMKDGETEIKIMTIMSSTNYAIRLIDSLLGDKGAVIVMEKAKCDMKTFIQEEKSDTSPDFISKYFTAIL 185
[Close]
BLAST of Kinase-like domain-containing protein vs. Planmine SMEST
Match: SMESG000017670.1 (SMESG000017670.1)

HSP 1 Score: 205.682 bits (522), Expect = 1.241e-62
Identity = 101/111 (90.99%), Postives = 104/111 (93.69%), Query Frame = 2 
Query: 1148 SDTEDQLNDDILNQNIDPEYSYQTPLKSHKKNMLKTPKKTAMNNISSYIISPIVKFQGNIDSSYVDDNVDIEASIILNYDVDSQIDNIINLTERTSKILFGSYECQKLIGE 1480
            +DT+DQLNDDILNQNIDPEYSY+TPLK HKKNMLKTPKKTAMNN SSYIISPIVK QGN DSSYVDDNVDIEASIILNYDVD QIDNIINLTERTSKI FG YECQKLIGE
Sbjct:    3 NDTKDQLNDDILNQNIDPEYSYRTPLKCHKKNMLKTPKKTAMNNASSYIISPIVKLQGNTDSSYVDDNVDIEASIILNYDVDYQIDNIINLTERTSKIFFGCYECQKLIGE 113
The following BLAST results are available for this feature:
BLAST of Kinase-like domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TTK5.605e-2327.95TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12... [more]
TTK5.795e-2327.95TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12... [more]
TTK5.795e-2327.95TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12... [more]
STK367.055e-2027.61serine/threonine kinase 36 [Source:HGNC Symbol;Acc... [more]
NEK69.990e-2029.63NIMA related kinase 6 [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of Kinase-like domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ZK524.45.615e-1526.47pep chromosome:WBcel235:I:7460858:7466424:-1 gene:... [more]
nekl-36.044e-1528.33Serine/threonine-protein kinase nekl-3 [Source:Un... [more]
nekl-36.044e-1528.33Serine/threonine-protein kinase nekl-3 [Source:Un... [more]
unc-827.989e-1526.74pep chromosome:WBcel235:IV:7425729:7444660:1 gene:... [more]
unc-827.998e-1526.74pep chromosome:WBcel235:IV:7428926:7444648:1 gene:... [more]
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BLAST of Kinase-like domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mps11.398e-2431.12gene:FBgn0000063 transcript:FBtr0083478[more]
Mps12.119e-2131.36gene:FBgn0000063 transcript:FBtr0331348[more]
Nuak11.467e-1525.34gene:FBgn0262617 transcript:FBtr0305354[more]
Nuak11.467e-1525.34gene:FBgn0262617 transcript:FBtr0305353[more]
Nuak11.467e-1525.34gene:FBgn0262617 transcript:FBtr0305352[more]
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BLAST of Kinase-like domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttk1.356e-2129.14ttk protein kinase [Source:NCBI gene;Acc:317763][more]
ttk1.367e-2129.14ttk protein kinase [Source:NCBI gene;Acc:317763][more]
tssk61.446e-1729.29testis-specific serine kinase 6 [Source:ZFIN;Acc:Z... [more]
si:ch211-117c9.14.785e-1730.29si:ch211-117c9.1 [Source:ZFIN;Acc:ZDB-GENE-110411-... [more]
CABZ01040556.15.155e-1631.40NIMA related kinase 3 [Source:NCBI gene;Acc:100536... [more]
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BLAST of Kinase-like domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttk1.538e-2230.36TTK protein kinase [Source:NCBI gene;Acc:780054][more]
ttk1.710e-2230.36TTK protein kinase [Source:NCBI gene;Acc:780054][more]
ttk1.968e-2230.36TTK protein kinase [Source:NCBI gene;Acc:780054][more]
lhfpl41.919e-2031.28LHFPL tetraspan subfamily member 4 [Source:Xenbase... [more]
lhfpl42.184e-2031.28LHFPL tetraspan subfamily member 4 [Source:Xenbase... [more]
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BLAST of Kinase-like domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ttk6.473e-2329.53Ttk protein kinase [Source:MGI Symbol;Acc:MGI:1194... [more]
Nek64.902e-1929.26NIMA (never in mitosis gene a)-related expressed k... [more]
Nek65.495e-1928.94NIMA (never in mitosis gene a)-related expressed k... [more]
Nek65.495e-1928.94NIMA (never in mitosis gene a)-related expressed k... [more]
Tssk69.923e-1926.55testis-specific serine kinase 6 [Source:MGI Symbol... [more]
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BLAST of Kinase-like domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8SSH4|MPS1_ENCCU1.277e-2631.68Probable serine/threonine-protein kinase MPS1 homo... [more]
sp|Q54UL8|MPS1_DICDI2.005e-2430.18Probable serine/threonine-protein kinase mps1 OS=D... [more]
sp|O94235|MPH1L_SCHPO9.730e-2427.78Serine/threonine-protein kinase mph1 OS=Schizosacc... [more]
sp|P33981|TTK_HUMAN2.692e-2227.95Dual specificity protein kinase TTK OS=Homo sapien... [more]
sp|P35761|TTK_MOUSE5.193e-2229.53Dual specificity protein kinase TTK OS=Mus musculu... [more]
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BLAST of Kinase-like domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5E4N6Y61.790e-3232.97Protein kinase domain,Protein kinase-like domain,P... [more]
A0A1X2H7782.384e-3232.97Kinase-like domain-containing protein OS=Syncephal... [more]
A0A016T2101.244e-3131.73Protein kinase domain-containing protein OS=Ancylo... [more]
J9JXK64.591e-3134.41Protein kinase domain-containing protein OS=Acyrth... [more]
A0A2A6CAV31.147e-3032.00Mrpl-4 OS=Pristionchus pacificus OX=54126 GN=PRIPA... [more]
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BLAST of Kinase-like domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttk5.488e-2331.41ttk protein kinase [Source:NCBI gene;Acc:317763][more]
tssk67.843e-1828.22testis-specific serine kinase 6 [Source:ZFIN;Acc:Z... [more]
ENSAMXT00000054199.11.434e-1627.04testis-specific serine/threonine-protein kinase 6-... [more]
nuak1a1.685e-1630.00NUAK family kinase 1 [Source:NCBI gene;Acc:1030296... [more]
pdpk1b1.781e-1629.053-phosphoinositide-dependent protein kinase 1 [Sou... [more]
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BLAST of Kinase-like domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
STK363.390e-1928.92serine/threonine kinase 36 [Source:HGNC Symbol;Acc... [more]
tssk62.468e-1726.34testis-specific serine kinase 6 [Source:ZFIN;Acc:Z... [more]
myo3a7.784e-1725.44myosin IIIA [Source:ZFIN;Acc:ZDB-GENE-041026-4][more]
MARK33.815e-1628.09microtubule affinity regulating kinase 3 [Source:H... [more]
MARK34.684e-1627.56microtubule affinity regulating kinase 3 [Source:H... [more]
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BLAST of Kinase-like domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
MPS12.555e-2227.78Dual-specificity kinase; autophosphorylation requi... [more]
CDC151.423e-1824.62Protein kinase of the Mitotic Exit Network; locali... [more]
KIC17.505e-1724.15Protein kinase of the PAK/Ste20 family, required f... [more]
CDC51.082e-1623.81Polo-like kinase; controls targeting and activatio... [more]
SNF14.414e-1626.96AMP-activated S/T protein kinase; forms a complex ... [more]
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BLAST of Kinase-like domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO307523.979e-2227.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO491382.374e-1926.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO490901.170e-1631.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO461857.589e-1628.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412421.244e-1526.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Kinase-like domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttk3.180e-2328.30TTK protein kinase [Source:NCBI gene;Acc:101155587... [more]
nek65.167e-2128.47NIMA related kinase 6 [Source:NCBI gene;Acc:101173... [more]
nuak1b1.268e-1730.48NUAK family kinase 1 [Source:NCBI gene;Acc:1011696... [more]
si:ch211-117c9.11.441e-1726.59NUAK family SNF1-like kinase 1 [Source:NCBI gene;A... [more]
nek71.072e-1527.14NIMA related kinase 7 [Source:NCBI gene;Acc:101170... [more]
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BLAST of Kinase-like domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000044282.10.000e+099.56SMESG000044282.1[more]
SMESG000044282.10.000e+099.56SMESG000044282.1[more]
SMESG000071238.11.310e-14478.78SMESG000071238.1[more]
SMESG000008316.11.955e-8165.58SMESG000008316.1[more]
SMESG000017670.11.241e-6290.99SMESG000017670.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004904 ID=SMED30004904|Name=Kinase-like domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2285bp
CGAAAATGGAATTTGAGAAAAATAACTTAATATATATAAATTTTTCATGT
TAAATATTTGCATTTAGTCGGTGGCCCAATTAGGCCATTTTCTGACCGGA
ACCAATAACAGGATTTTTTTGAAGGTGTTAGATTTAAAAAATAATAAAAT
TTTCGCACCTGAATATCAATTGATAGTTTTGAAGAATTTTTAATATAAAA
TGGAGAAATATATTAAAGAATTCCAAGACTTCATCAAATTTAGTTTGAGA
ACAATTGACGATTTAACTTATTATTTGAATGCTTCAAAGCATTACAAAGA
AGTGGATTTGCTAGTGGAGACCATTGAAGAAATAATGGTTAATGACACCT
TGGACAATAGATTCGAATTATTTTTGAGGATTTATGAAACACTTTCTCTA
GTTTTAACTGAGCCACCCGATGCTTATTTGAAATACAAATTTCGATATTT
TATAATGAATTGGCAAGTTGATAGTTCAGAAGCTATTTTTAATTTGAATT
TGATAATTAAAGAAATTAATGTTTATAATGATCAACTGATATCGGCTGTT
GCTTTTTATAAATTAGTTTTTGTGTCGAAAGATGAAGCTCTGCAATTTCT
ACGACAACCATTTCAGTGTACTGAGGTCTTTTTAAAAAGAATTATTAGCA
TGGTAACGGAGAATGACTATTATTCCTTAATTAATCGAATGGGGGAATAT
TGGTATTTCCCTGTAATCAAACAAAATGATAAATGTATGGAATTGATACA
GAAAATACAAAGTCGAACCCTCAATGTCAAAAAAGTAGAATTTATTATCA
ATTGCACAGTCTCTTCAGATATTCCCAATAATATAACAAATACATCAAAT
AAAAATTTGAATTATTCACCAGTTCCAGAGAGTCCTGTATTGAATACGAT
TTCGCGTACATCAAATAATAATCGCAGAGCACATCCACTGGTAAAGATTG
AAGATAGTAAGGACCATACAACTATTGAAGGAACACAAAACCAAAATATA
GAAATTAATGATCCATTGTGCAGTTCACTCGATGATTCTTTTATGTTTCT
CACTATCAAAAATACTAATAGTGATTCCACCAGGAAACAAACTTTAGACG
ATAATTTTGATTCTTCAGAAACGACTATTCAAGCGAAGCCTCACACTAGT
GACACCGAGGATCAATTGAATGATGATATATTGAACCAAAATATTGATCC
AGAATATTCGTATCAAACTCCATTGAAATCTCACAAGAAAAATATGCTAA
AAACTCCAAAGAAAACCGCAATGAATAATATCAGCTCTTATATAATCTCT
CCTATTGTAAAATTTCAGGGAAATATTGACAGTAGTTATGTCGATGATAA
TGTCGACATCGAGGCTTCCATAATACTCAATTATGATGTAGACTCCCAAA
TTGATAACATTATCAACCTCACAGAAAGAACTTCTAAAATTCTTTTCGGG
TCTTATGAGTGTCAAAAATTGATCGGAGAAGGAGGAATGAGCAAAGTTTA
TTCAGCCATTGGAAAACACGATCGTCAAACCTACGCTGTGAAAGTAATAG
TTTTTGAAAATAATTTAGTTATGAAAGATGTGGAAACTGAAATTAAAATT
ATGACAATAATGTCCTCAACCAATTATGCCATTCGGTTGATTGATAGCCT
GATCGGAGATAAAGGTGCTGTCATTGTTATGGAGAAAGCTAAATGTGATA
TGAAAACATTTATCCAAGAGAAACAACCGGATATATCACCGGATTTTATA
TTGAAATATTGGACAGCAATGCTCAGATGTGTTAAAGCTCTTCATGATAA
AAGAATTTCACATCTCGACTTGAAGTTACAAAATTTTGTAATGACAGAAT
CTGAACGAATTAAATTGATAGATTTCGGTATTAGTAGGCAATTATCTCTC
GATACTTCGCTAATATCTGACGGGGAAAGTTCAGGAACCTTTATTTTCAT
GAGTCCTGAACTGCTTAGCGGTAAGAGTGAATTTGAGCCGAAAAAATGCG
ACGTTTGGGCAATGGGAATTGTATTGTATACGCTGATATACAATTTTCAG
CCTCGATTTAAATCTGGAAATAAAGTTTATGCTTCAACATCTTGTCAAAA
TTTTTCACAATTACTCACCAATAAGAGATATAGCATATTCAAACCTGACT
CTAAGAAATTAACTCCATTGCTACGACAGATTATGGACATGTGCCTGGTT
TATGAGTTTAAGCAGAGACCTTCAGTTGAGGAACTTTTGAAACTGATTTC
TCTGCAATAAATGACAACTTATTGACAACTACGCT
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protein sequence of SMED30004904-orf-1

>SMED30004904-orf-1 ID=SMED30004904-orf-1|Name=SMED30004904-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=687bp
MEKYIKEFQDFIKFSLRTIDDLTYYLNASKHYKEVDLLVETIEEIMVNDT
LDNRFELFLRIYETLSLVLTEPPDAYLKYKFRYFIMNWQVDSSEAIFNLN
LIIKEINVYNDQLISAVAFYKLVFVSKDEALQFLRQPFQCTEVFLKRIIS
MVTENDYYSLINRMGEYWYFPVIKQNDKCMELIQKIQSRTLNVKKVEFII
NCTVSSDIPNNITNTSNKNLNYSPVPESPVLNTISRTSNNNRRAHPLVKI
EDSKDHTTIEGTQNQNIEINDPLCSSLDDSFMFLTIKNTNSDSTRKQTLD
DNFDSSETTIQAKPHTSDTEDQLNDDILNQNIDPEYSYQTPLKSHKKNML
KTPKKTAMNNISSYIISPIVKFQGNIDSSYVDDNVDIEASIILNYDVDSQ
IDNIINLTERTSKILFGSYECQKLIGEGGMSKVYSAIGKHDRQTYAVKVI
VFENNLVMKDVETEIKIMTIMSSTNYAIRLIDSLIGDKGAVIVMEKAKCD
MKTFIQEKQPDISPDFILKYWTAMLRCVKALHDKRISHLDLKLQNFVMTE
SERIKLIDFGISRQLSLDTSLISDGESSGTFIFMSPELLSGKSEFEPKKC
DVWAMGIVLYTLIYNFQPRFKSGNKVYASTSCQNFSQLLTNKRYSIFKPD
SKKLTPLLRQIMDMCLVYEFKQRPSVEELLKLISLQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0004712protein serine/threonine/tyrosine kinase activity
GO:0016301kinase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR027084Prot_kin_Mps1_fam
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0007093mitotic cell cycle checkpoint
GO:0016310phosphorylation
GO:0051304chromosome separation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 419..685
e-value: 1.3E-48
score: 177.4
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 419..681
e-value: 1.9E-44
score: 152.0
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 419..686
score: 33.262
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 399..685
e-value: 4.0E-51
score: 175.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 302..324
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 303..324
NoneNo IPR availablePANTHERPTHR22974MIXED LINEAGE PROTEIN KINASEcoord: 233..681
IPR027084Protein kinase Mps1 familyPANTHERPTHR22974:SF21DUAL SPECIFICITY PROTEIN KINASE TTKcoord: 233..681
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 536..548
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 425..448
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 413..682