Glycine receptor subunit alpha-3
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30004877 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRB (glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329]) HSP 1 Score: 243.432 bits (620), Expect = 2.594e-73 Identity = 141/443 (31.83%), Postives = 242/443 (54.63%), Query Frame = 3
Query: 300 IMDKILQNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTK-VETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTV------AQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQI--------------LNRNELEFCEELDILLTAQQY--------ANNYHSQESAHQIKR---QKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
I++++L +Y RP + V+V + + + S+ + M+Y +++LRQ W D RL+ + +F+ ++ V P++ LW PDLFF N K H +T+ N L+ +F +G+VL S ++++ SC +DL +PMDTQ C+M + S+GYT D L+F W +P++L + +P+F+ + +E +CT TG+Y+C++ +F LRRQ+G Y++ + P LIV++SWL+FW++ +A AR+ LG+ ++L + ++ + ++ LP+VSY+KA+DVWLIAC++F +L+E+AV + + +K K+E D +++ N H+ T Q+ L N+ L Y NN + A K+ K + +ID+Y+R LFP CF+F+N YW YL
Sbjct: 59 ILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPS--DFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQL-EKIALPQFDIKKEDIEYGNCTKYYKG-TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGGNVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL 497
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRB (glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329]) HSP 1 Score: 243.432 bits (620), Expect = 2.594e-73 Identity = 141/443 (31.83%), Postives = 242/443 (54.63%), Query Frame = 3
Query: 300 IMDKILQNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTK-VETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTV------AQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQI--------------LNRNELEFCEELDILLTAQQY--------ANNYHSQESAHQIKR---QKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
I++++L +Y RP + V+V + + + S+ + M+Y +++LRQ W D RL+ + +F+ ++ V P++ LW PDLFF N K H +T+ N L+ +F +G+VL S ++++ SC +DL +PMDTQ C+M + S+GYT D L+F W +P++L + +P+F+ + +E +CT TG+Y+C++ +F LRRQ+G Y++ + P LIV++SWL+FW++ +A AR+ LG+ ++L + ++ + ++ LP+VSY+KA+DVWLIAC++F +L+E+AV + + +K K+E D +++ N H+ T Q+ L N+ L Y NN + A K+ K + +ID+Y+R LFP CF+F+N YW YL
Sbjct: 59 ILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPS--DFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQL-EKIALPQFDIKKEDIEYGNCTKYYKG-TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGGNVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL 497
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA2 (glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327]) HSP 1 Score: 240.35 bits (612), Expect = 1.139e-72 Identity = 137/389 (35.22%), Postives = 218/389 (56.04%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLY-------QWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ SV + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+ NG+VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W P+++ + +P+F + E CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K + + +++ D+ R+ SR+N + H +Q D AN ++K + + +ID SR FP F+ +N YWI Y II
Sbjct: 81 SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHY--NTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRE--SRFNFS-GYGMGHCLQVK--------------DGTAVKATPANPLPQPPKDGDAIKKKFVDRAK--RIDTISRAAFPLAFLIFNIFYWITYKII 444
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA2 (glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327]) HSP 1 Score: 239.58 bits (610), Expect = 2.147e-72 Identity = 136/389 (34.96%), Postives = 218/389 (56.04%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLY-------QWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+ NG+VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W P+++ + +P+F + E CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K + + +++ D+ R+ SR+N + H +Q D AN ++K + + +ID SR FP F+ +N YWI Y II
Sbjct: 81 SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHY--NTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRE--SRFNFS-GYGMGHCLQVK--------------DGTAVKATPANPLPQPPKDGDAIKKKFVDRAK--RIDTISRAAFPLAFLIFNIFYWITYKII 444
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA2 (glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327]) HSP 1 Score: 236.884 bits (603), Expect = 2.321e-72 Identity = 135/380 (35.53%), Postives = 214/380 (56.32%), Query Frame = 3
Query: 417 MEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLY-------QWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+ NG+VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W P+++ + +P+F + E CT T G ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K + + +++ D+ R+ SR+N + H +Q D AN ++K + + +ID SR FP F+ +N YWI Y II
Sbjct: 1 MDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNT--GKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRE--SRFNFS-GYGMGHCLQVK--------------DGTAVKATPANPLPQPPKDGDAIKKKFVDRAK--RIDTISRAAFPLAFLIFNIFYWITYKII 355
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: glc-2 (Glutamate-gated chloride channel subunit beta [Source:UniProtKB/Swiss-Prot;Acc:Q17328]) HSP 1 Score: 242.276 bits (617), Expect = 5.388e-74 Identity = 149/435 (34.25%), Postives = 238/435 (54.71%), Query Frame = 3
Query: 288 TRERIMDKILQNYSLNERPIESNQT-------RVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMEL--GNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQ-ELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQY-----ANNYHSQES-AHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVSN 1544
+ + I++ +L+NY + RP +N + RV + +++L+ ++V NMEYS L R+ W+D RL ++NL F + + L P +K LW+PD FF K + H++ N +R++P+G++LYS +I++ SC M LQ YP+D QSC ++ SY +T++ + + W + P++L G +P F DCT S T TG Y CL+ + +RQ YLV + P T+IVIVSW++FW+ + + R+ LG+ TLL + T S I+ LP VSY+K +DVWL AC FV GALLE+A S YQ D VRQ + SR A Q+ R +LE ++ A+ Y + + ++E+ +++R + +KID Y+R++ P F+ +N YW+ LI+ +N
Sbjct: 28 SEQEILNALLKNYDMRVRPPPANSSTEGAVNVRVNIMIRMLS--KIDVVNMEYSIQLTFREQWIDPRLAYENLG-FYNPPAFLTVPHVKKSLWIPDTFFPTEKAAHRHLIDMENMFLRIYPDGKILYSSRISLTSSCPMRLQLYPLDYQSCNFDLVSYAHTMNDIMYEWDPSTPVQLKPGVGSDLPNFILKNYTTNADCT--SHTNTGSYGCLRMQLLFKRQFSYYLVQLYAPTTMIVIVSWVSFWIDLHSTAGRVALGVTTLLTMTTMQSAINAKLPPVSYVKVVDVWLGACQTFVFGALLEYAFVS--------YQ------DSVRQNDRSREKAARKAQR----------RREKLE-------MVDAEVYQPPCTCHTFEARETFRDKVRRYFTKPDYLPAKIDFYARFVVPLAFLAFNVIYWVSCLIMSAN 426
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: glc-1 (Glutamate-gated chloride channel alpha [Source:UniProtKB/Swiss-Prot;Acc:G5EBR3]) HSP 1 Score: 236.884 bits (603), Expect = 1.001e-71 Identity = 145/406 (35.71%), Postives = 224/406 (55.17%), Query Frame = 3
Query: 321 NYSLNERPIESNQTRVMVFMKVL--AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMEL--GNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQ---YANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYW 1517
Y RP N V+V + +L I+ ++V NMEYS L LR+ W+D RL + + + V ++ ++W+PD FF N K+ Y H + KPN L+R+ +G VLYS +I++ SC M LQ YPMD Q C +++ SY YT +++ W + +P++L G + +P F T T CT S T TG YSCL+ L+R+ YL+ +IP+ ++VIVSW++FW A+PAR+TLG+ TLL + Q++GI+ LP VSYIKAIDVW+ AC+ F+ ALLEFA+ + +A K V R E + + + Q H+ +++ N+ E + + L +Q + N ++ + I + ++D+ SR LFP F +N YW
Sbjct: 74 GYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQ---PDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQL-TNTSTTYCT--SVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIAN-------KQGVERKARTEREKAEIPL-LQNLHNDVPTKVFNQEE----KVRTVPLNRRQMNSFLNLLETKTEWNDISK----------RVDLISRALFPVLFFVFNILYW 451
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: glc-1 (Glutamate-gated chloride channel alpha [Source:UniProtKB/Swiss-Prot;Acc:G5EBR3]) HSP 1 Score: 236.884 bits (603), Expect = 1.001e-71 Identity = 145/406 (35.71%), Postives = 224/406 (55.17%), Query Frame = 3
Query: 321 NYSLNERPIESNQTRVMVFMKVL--AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMEL--GNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQ---YANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYW 1517
Y RP N V+V + +L I+ ++V NMEYS L LR+ W+D RL + + + V ++ ++W+PD FF N K+ Y H + KPN L+R+ +G VLYS +I++ SC M LQ YPMD Q C +++ SY YT +++ W + +P++L G + +P F T T CT S T TG YSCL+ L+R+ YL+ +IP+ ++VIVSW++FW A+PAR+TLG+ TLL + Q++GI+ LP VSYIKAIDVW+ AC+ F+ ALLEFA+ + +A K V R E + + + Q H+ +++ N+ E + + L +Q + N ++ + I + ++D+ SR LFP F +N YW
Sbjct: 74 GYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQ---PDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQL-TNTSTTYCT--SVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIAN-------KQGVERKARTEREKAEIPL-LQNLHNDVPTKVFNQEE----KVRTVPLNRRQMNSFLNLLETKTEWNDISK----------RVDLISRALFPVLFFVFNILYW 451
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: glc-3 (Glutamate-gated ChLoride channel; Glutamate-gated chloride channel subunit [Source:UniProtKB/TrEMBL;Acc:G5EEZ3]) HSP 1 Score: 236.113 bits (601), Expect = 3.378e-71 Identity = 166/483 (34.37%), Postives = 256/483 (53.00%), Query Frame = 3
Query: 225 NIFIFLLAIHVGCNSCSVAGITRERIMDKIL-QNYSLNERP------IESNQTRVMVFMKVL--AINSVNVSNMEYSTDLYLRQLWVDVRLRW----DNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMEL--GNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKS--------------------------EVRDIVRQELSRWNLAINRQKTHHMQTSQI---LNRNELEFCEELDILLTAQQYANNYHSQESAHQIK-----RQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYY 1526
NI + + VG N C + T I+ K+L + Y RP I V+V++ +L +I+ ++ NMEYS L R+ WVD RL + D+ +F + ++W+PD FF+N K+ + H + KPN L+R+ +G +LYS +I+M SC M LQ YPMD Q+C +++ SY YT + +++ W +T+P++L G + +P F V+T CT S T TG YSCL+ + LRRQ YL+ +IP+T++VIVSW++FW+ AVPAR+TLG+ TLL + TQASGI+ LP VSY KAIDVW+ AC+ F+ GALLEFA + ++ + + K+ E + V L++ RQ + S++ +N N E E I+ A+ + + I+ R ++ + + D+ SR LFP+ F+ +NF YW Y
Sbjct: 8 NILLIVAFWIVGGN-CDASSDTE--IIKKLLGKGYDWRVRPPGINLTIPGTHGAVIVYVNMLIRSISKIDDVNMEYSVQLTFREEWVDGRLAYGFPGDSTPDFLILTAG-------QQIWMPDSFFQNEKQAHKHDIDKPNVLIRIHRDGRILYSVRISMVLSCPMHLQYYPMDVQTCLIDLASYAYTENDIEYRWKKTDPVQLKKGLHSSLPSFEL-NNVDTTLCT--SKTNTGTYSCLRTVLELRRQFSYYLLQLYIPSTMLVIVSWVSFWLDRGAVPARVTLGVTTLLTMTTQASGINAKLPPVSYTKAIDVWIGACLTFIFGALLEFAWVTYISSRSFYKRNKNCSSRNSLLIETKQALIIPNTVVAQFPEHPEEVEMGLAQAPDVWIRQSGNGKTVSRVNGHINHNNDEAAEL--IIFDAKHKNRRFVWWTNFRNIRLIRWIRNRLNVDDNAKRADLISRVLFPTLFVCFNFVYWTKY 475
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: avr-15 (pep chromosome:WBcel235:V:13498786:13502743:-1 gene:WBGene00000233.1 transcript:R11G10.1b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-15) HSP 1 Score: 230.72 bits (587), Expect = 4.240e-69 Identity = 146/418 (34.93%), Postives = 225/418 (53.83%), Query Frame = 3
Query: 300 IMDKIL-QNYSLNERP------IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMEL--GNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYY 1526
I++ +L + Y RP I V V M + +I+ ++ NMEYS L R+ WVD RL + + + + + +W+PD FF+N K+ Y H++ KPN L+R+ +G +LYS +I++ SC M LQ YPMD Q C +++ SY YT +++ W + P++L G + +P F T T CT S T TG YSCL+ + LRRQ YL+ +IP+ ++VIVSW++FW+ AVPAR+TLG+ TLL + TQ+SGI+ LP V+YIKAIDVW+ AC+ F+ ALLEFA + +A K + R E + L + + + + + E E ++T + N S + + K + + D+ SR +FP F+ +N YW +Y
Sbjct: 75 ILEHLLTRGYDHRVRPPGEDGTIHGGPVVVSVNMLLRSISKIDNVNMEYSVQLTFRESWVDKRLSFGVKGDAQ---PDFLILTAGQEIWMPDSFFQNEKQAYKHMIDKPNVLIRVHKDGTILYSVRISLVLSCPMHLQYYPMDVQQCFIDLASYAYTTKDIEYVWKEETPVQLKAGLSSSLPSFQL-TNTSTTYCT--SKTNTGSYSCLRTIIQLRRQFSYYLLQLYIPSCMLVIVSWVSFWIDRTAVPARVTLGVTTLLTMTTQSSGINAKLPPVAYIKAIDVWIGACMTFIFCALLEFAWVTYIAN-------KQDANKRARTEREKAELPFLQNSHNDVWVPREVAEQERE-------VMTVRM---NRRQTNSVWKWIKTKTEWNDKSKRADLISRVMFPVLFLTFNISYWTHY 469
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0343789) HSP 1 Score: 246.514 bits (628), Expect = 2.500e-75 Identity = 153/432 (35.42%), Postives = 239/432 (55.32%), Query Frame = 3
Query: 294 ERIMDKILQ--NYSLNERPIESNQT------RVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLA-------INRQKTHHMQTSQILNRNELEFCEEL--DILLTAQQYAN---NYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
++++D+IL Y RP N T RV +F++ +I+ ++ MEYS L R+ W D RL++D++ + ++ + +R+W+PDLFF N KEG+ H + PN +R+FPNG VLYS +I++ +C M+L+ YP+D Q C + + SYG+T + L F W + +P+++ N+ +P F K T+ C +S T TG YSCLK + +R+ YL+ +IP ++VIVSW++FW+ AVPAR++LG+ TLL + TQ SGI+ +LP VSY KAIDVW C+ FV GALLEFA+ + ++ + E R++L + +L + T M+ + L + L ++ + A + N + S+ Q R K +IDV SR FP F +N YW YL
Sbjct: 34 KKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVR--SISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTL-EKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSDRAADMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRQCSRSK--------RIDVISRITFPLVFALFNLVYWSTYL 448
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0335416) HSP 1 Score: 244.973 bits (624), Expect = 8.974e-75 Identity = 150/424 (35.38%), Postives = 235/424 (55.42%), Query Frame = 3
Query: 294 ERIMDKILQ--NYSLNERPIESNQT------RVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQ--WKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEI--EESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
++++D+IL Y RP N T RV +F++ +I+ ++ MEYS L R+ W D RL++D++ + ++ + +R+W+PDLFF N KEG+ H + PN +R+FPNG VLYS +I++ +C M+L+ YP+D Q C + + SYG+T + L F W + +P+++ N+ +P F K T+ C +S T TG YSCLK + +R+ YL+ +IP ++VIVSW++FW+ AVPAR++LG+ TLL + TQ SGI+ +LP VSY KAIDVW C+ FV GALLEFA+ + A + +++ K + RD+ + L + ++ ++ D L ++ H Q + LS+ +IDV SR FP F +N YW YL
Sbjct: 34 KKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVR--SISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTL-EKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVN-YASRSDMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPG-------DPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYL 440
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0335420) HSP 1 Score: 244.588 bits (623), Expect = 1.092e-74 Identity = 149/424 (35.14%), Postives = 234/424 (55.19%), Query Frame = 3
Query: 294 ERIMDKILQ--NYSLNERP-----IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQ--WKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEI--EESKIDVYSRYLFPSCFIFYNFCYWIYYLI 1532
++++D+IL Y RP ++ T V V M + +I+ ++ MEYS L R+ W D RL++D++ + ++ + +R+W+PDLFF N KEG+ H + PN +R+FPNG VLYS +I++ +C M+L+ YP+D Q C + + SYG+T + L F W + +P+++ N+ +P F K T+ C +S T TG YSCLK + +R+ YL+ +IP ++VIVSW++FW+ AVPAR++LG+ TLL + TQ SGI+ +LP VSY KAIDVW C+ FV GALLEFA+ + A + +++ K + RD+ + L + ++ ++ D L ++ H Q + LS+ +IDV SR FP F +N YW YL
Sbjct: 34 KKVLDQILGAGKYDARIRPSGINGTDNKATNVSVNMFLRSISKIDDYKMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTL-EKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVN-YASRSDMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPG-------DPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYLF 442
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0335417) HSP 1 Score: 244.202 bits (622), Expect = 2.342e-74 Identity = 154/433 (35.57%), Postives = 243/433 (56.12%), Query Frame = 3
Query: 294 ERIMDKILQ--NYSLNERPIESNQT------RVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQ----QKKLYQ--WKSEVRDIVRQELSRWN--LAINRQKTHHMQTSQILNRNELEFCEEL--DILLTAQQYAN---NYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
++++D+IL Y RP N T RV +F++ +I+ ++ MEYS L R+ W D RL++D++ + ++ + +R+W+PDLFF N KEG+ H + PN +R+FPNG VLYS +I++ +C M+L+ YP+D Q C + + SYG+T + L F W + +P+++ N+ +P F K T+ C +S T TG YSCLK + +R+ YL+ +IP ++VIVSW++FW+ AVPAR++LG+ TLL + TQ SGI+ +LP VSY KAIDVW C+ FV GALLEFA+ + ++ + +++ K + RD+ + L + L + T M+ + L + L ++ + A + N + S+ Q R K +IDV SR FP F +N YW YL
Sbjct: 34 KKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVR--SISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTL-EKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRQCSRSK--------RIDVISRITFPLVFALFNLVYWSTYL 449
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0335418) HSP 1 Score: 243.817 bits (621), Expect = 2.701e-74 Identity = 153/432 (35.42%), Postives = 242/432 (56.02%), Query Frame = 3
Query: 294 ERIMDKILQ--NYSLNERP-----IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQ----QKKLYQ--WKSEVRDIVRQELSRWN--LAINRQKTHHMQTSQILNRNELEFCEEL--DILLTAQQYAN---NYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
++++D+IL Y RP ++ T V V M + +I+ ++ MEYS L R+ W D RL++D++ + ++ + +R+W+PDLFF N KEG+ H + PN +R+FPNG VLYS +I++ +C M+L+ YP+D Q C + + SYG+T + L F W + +P+++ N+ +P F K T+ C +S T TG YSCLK + +R+ YL+ +IP ++VIVSW++FW+ AVPAR++LG+ TLL + TQ SGI+ +LP VSY KAIDVW C+ FV GALLEFA+ + ++ + +++ K + RD+ + L + L + T M+ + L + L ++ + A + N + S+ Q R K +IDV SR FP F +N YW YL
Sbjct: 34 KKVLDQILGAGKYDARIRPSGINGTDNKATNVSVNMFLRSISKIDDYKMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTL-EKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRQCSRSK--------RIDVISRITFPLVFALFNLVYWSTYL 450
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra3 (glycine receptor, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-020402-1]) HSP 1 Score: 246.128 bits (627), Expect = 4.162e-75 Identity = 143/431 (33.18%), Postives = 236/431 (54.76%), Query Frame = 3
Query: 276 VAGITRERIMDKIL---QNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQ-KKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEE------SKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
A ++ +DK++ Y RP + V + + + S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K + H +T N L+R+F NG VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W + P+++ + + +P+F + + CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K+L +++ + ++E R + L F + ANN + S + K E+ + KID SR FP F+F+N YW+ Y I+
Sbjct: 38 AAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEKGPVQVADGLTLPQFILKDESDLRYCTKH--YNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRKKSGKEEEVR--------------------ESRLSFTPNAGKDGAVPKTANNAATTPSEPAVAPGKSHEEMRKLFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKIL 442
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra4b (glycine receptor, alpha 4b [Source:ZFIN;Acc:ZDB-GENE-020402-2]) HSP 1 Score: 242.662 bits (618), Expect = 4.361e-74 Identity = 146/451 (32.37%), Postives = 247/451 (54.77%), Query Frame = 3
Query: 213 QQQSNIFIFLL-----AIHVGCNSCSVAGITRERIMDKIL---QNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESK-IDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ SN+ +F+L + + S ++ +DK++ Y RP + V + + + S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+F NG VLYS ++T+ SC MDL+ +PMDTQ+C M + S+GYT++ L F W P+++ +++ +P+F + + CT TG ++C++ F L RQ+G YL+ +IP+ L VI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K + +R +RQE NR++ Q++ L+ F + I+R+ +E++K ID SR +FP F+ +N YW+ Y ++
Sbjct: 2 KHNSNLVVFVLLWCVFSKELKSPSVRTKPMSPSDFLDKLMGKTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYKEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTCTMQLESFGYTMNDLIFQWLDEGPVQVADDLMLPQFVLKEEKDLGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQYKEF---FRLRRKLRQEQR------NRERDPLTQSNGPLSEAAAMFA--------------GLPPGHALFDIRRR----FVEQAKRIDTISRAVFPLSFLVFNVFYWVTYKVL 419
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra4b (glycine receptor, alpha 4b [Source:ZFIN;Acc:ZDB-GENE-020402-2]) HSP 1 Score: 241.121 bits (614), Expect = 2.868e-73 Identity = 136/383 (35.51%), Postives = 221/383 (57.70%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESK-IDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+F NG VLYS ++T+ SC MDL+ +PMDTQ+C M + S+GYT++ L F W P+++ +++ +P+F + + CT TG ++C++ F L RQ+G YL+ +IP+ L VI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K + +R +RQE RN EF + + A +A + I+R+ +E++K ID SR +FP F+ +N YW+ Y ++
Sbjct: 84 SFGSITETTMDYRLNVFLRQQWNDPRLAYKEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTCTMQLESFGYTMNDLIFQWLDEGPVQVADDLMLPQFVLKEEKDLGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQYKEF---FRLRRKLRQE----------------------QRNRFEFSPY--VHMAAAMFA-GLPPGHALFDIRRR----FVEQAKRIDTISRAVFPLSFLVFNVFYWVTYKVL 428
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1]) HSP 1 Score: 241.121 bits (614), Expect = 3.590e-73 Identity = 140/392 (35.71%), Postives = 223/392 (56.89%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSL-VSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIE---------ESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ SV + M+Y +++LRQ W D RL + ++ +SSL + PS+ D +W PDLFF N K H +T N L+R+F +G VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W P+++ + + +P+F + + CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q+K + L + R++ Q + L L F + + A ++Q +QI++ IL E +ID SR FP F+ +N YWI Y II
Sbjct: 79 SFGSVTETTMDYRVNIFLRQKWNDPRLAYS-----EYPDSSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKDGTVLYSIRLTLILSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLDKGPVQVADGLTLPQFLIRDEKDLGYCTKHY--NTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAGVNFVSRQQKEF------------------LRLKRRQ-RRTQKEEDLQDGRLHF-SSYNTTTCVKDGAVVKNTQ--VNQIQQPSILKNTETNRKKFVDRAKRIDTISRAAFPLAFLIFNVFYWITYKII 441
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676]) HSP 1 Score: 238.81 bits (608), Expect = 2.150e-72 Identity = 141/420 (33.57%), Postives = 234/420 (55.71%), Query Frame = 3
Query: 294 ERIMDKILQNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQ-KKLYQWKSEVRDIVRQEL--SRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVS 1541
+++M K+ Y RP + V + + + S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+ NG VLYS +IT+ +C MDL+ +PMD Q+C M + S+GYT++ L F W + +++ + + +P+F + + CT T G ++C++A F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + +A+Q K+L +++ R + E R++ A +Q + + I + + E + R+ +S + +ID SR FP F+ +N YWI Y II S
Sbjct: 39 DKLMGKV-SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNT--GKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFQRRRRHLKEDEAGDGRFSFAAYGMGPACLQAK-----------DGMAIKGNNNNAPTSTNPPEKTVEEMRKLFISRAK--RIDTVSRVAFPLVFLIFNIFYWITYKIIRS 438
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: tal1 (T-cell acute lymphocytic leukemia 1 [Source:Xenbase;Acc:XB-GENE-479827]) HSP 1 Score: 249.98 bits (637), Expect = 2.045e-76 Identity = 140/389 (35.99%), Postives = 222/389 (57.07%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLY-------QWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ SV + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+F NG VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W T+P+++ + + +P+F + E CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K + + +S+ D+ R+ SR+N + H +Q + A + A IK++ + +ID SR FP F+ +N YWI Y II
Sbjct: 79 SFGSVTETTMDYRVNIFLRQTWNDPRLSYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWLSTSPVQVADGLTLPQFILKEENELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQSKEEDVARE--SRFNFS-GYGMGHCLQVKD-------------GTAVKATPPIPPPPQPKDADSIKKKFV---DRAKRIDTISRAAFPLAFLIFNIFYWITYKII 442
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: tal1 (T-cell acute lymphocytic leukemia 1 [Source:Xenbase;Acc:XB-GENE-479827]) HSP 1 Score: 248.825 bits (634), Expect = 3.366e-76 Identity = 139/389 (35.73%), Postives = 222/389 (57.07%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLY-------QWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+F NG VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W T+P+++ + + +P+F + E CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K + + +S+ D+ R+ SR+N + H +Q + A + A IK++ + +ID SR FP F+ +N YWI Y II
Sbjct: 65 SFGSIAETTMDYRVNIFLRQTWNDPRLSYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWLSTSPVQVADGLTLPQFILKEENELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQSKEEDVARE--SRFNFS-GYGMGHCLQVKD-------------GTAVKATPPIPPPPQPKDADSIKKKFV---DRAKRIDTISRAAFPLAFLIFNIFYWITYKII 428
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: tal1 (T-cell acute lymphocytic leukemia 1 [Source:Xenbase;Acc:XB-GENE-479827]) HSP 1 Score: 248.825 bits (634), Expect = 3.446e-76 Identity = 139/389 (35.73%), Postives = 222/389 (57.07%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLY-------QWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+F NG VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W T+P+++ + + +P+F + E CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K + + +S+ D+ R+ SR+N + H +Q + A + A IK++ + +ID SR FP F+ +N YWI Y II
Sbjct: 57 SFGSIAETTMDYRVNIFLRQTWNDPRLSYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWLSTSPVQVADGLTLPQFILKEENELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQSKEEDVARE--SRFNFS-GYGMGHCLQVKD-------------GTAVKATPPIPPPPQPKDADSIKKKFV---DRAKRIDTISRAAFPLAFLIFNIFYWITYKII 420
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: glrb (glycine receptor beta [Source:NCBI gene;Acc:779708]) HSP 1 Score: 249.595 bits (636), Expect = 3.898e-76 Identity = 147/451 (32.59%), Postives = 249/451 (55.21%), Query Frame = 3
Query: 276 VAGITRERIMDKILQNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTK-VETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQ-KKLYQWKSEVRDIVRQELSRWNLA----INRQKTH-HMQTSQI--------------LNRNELEFCEELDILLTAQQY--------ANNYHSQESAHQIKRQKILSEI---EESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
V + I++++L +Y RP + V+V + + + S+ + M+Y +++LRQ W D RL+ N +F+ ++ V P++ LW PDLFF N K H +T+ N L+ +F +G+VL S ++++ SC +DL +PMDTQ C+M + S+GYT D L+F W +P+++ + +P+F+ T+ +E +CT TG+Y+C++ +F LRRQ+G Y++ + P LIV++SWL+FW++ +A AR+ LG+ ++L + ++ + ++ LP+VSY+KAIDVWLIAC++F +L+E+AV + K++ K+++ + E N A +N T H+ T Q+ L N+ L Y NN + A K+ + E +ID+YSR LFP CF+F+N YW+ YL
Sbjct: 15 VPANSTSNILNRLLVSYDPRVRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLKLPN--DFRGSDALTVDPTMFKCLWKPDLFFANEKNANFHDVTQENILLFIFRDGDVLLSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQM-EKIALPQFDIKTEDIEYGNCTKYYKG-TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAQELPKVSYVKAIDVWLIACLLFGFASLVEYAVVQVLLNSPKRIEAEKAKIAKAEQAEGKGANAAKKNTVNGTGTPIHISTLQVGENRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPSEAKRIDLYSRALFPFCFLFFNVIYWLVYL 461
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: glrb (glycine receptor beta [Source:NCBI gene;Acc:779708]) HSP 1 Score: 249.595 bits (636), Expect = 4.693e-76 Identity = 147/451 (32.59%), Postives = 249/451 (55.21%), Query Frame = 3
Query: 276 VAGITRERIMDKILQNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTK-VETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQ-KKLYQWKSEVRDIVRQELSRWNLA----INRQKTH-HMQTSQI--------------LNRNELEFCEELDILLTAQQY--------ANNYHSQESAHQIKRQKILSEI---EESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
V + I++++L +Y RP + V+V + + + S+ + M+Y +++LRQ W D RL+ N +F+ ++ V P++ LW PDLFF N K H +T+ N L+ +F +G+VL S ++++ SC +DL +PMDTQ C+M + S+GYT D L+F W +P+++ + +P+F+ T+ +E +CT TG+Y+C++ +F LRRQ+G Y++ + P LIV++SWL+FW++ +A AR+ LG+ ++L + ++ + ++ LP+VSY+KAIDVWLIAC++F +L+E+AV + K++ K+++ + E N A +N T H+ T Q+ L N+ L Y NN + A K+ + E +ID+YSR LFP CF+F+N YW+ YL
Sbjct: 26 VPANSTSNILNRLLVSYDPRVRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLKLPN--DFRGSDALTVDPTMFKCLWKPDLFFANEKNANFHDVTQENILLFIFRDGDVLLSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQM-EKIALPQFDIKTEDIEYGNCTKYYKG-TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAQELPKVSYVKAIDVWLIACLLFGFASLVEYAVVQVLLNSPKRIEAEKAKIAKAEQAEGKGANAAKKNTVNGTGTPIHISTLQVGENRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPSEAKRIDLYSRALFPFCFLFFNVIYWLVYL 472
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra2 (glycine receptor, alpha 2 subunit [Source:MGI Symbol;Acc:MGI:95748]) HSP 1 Score: 240.35 bits (612), Expect = 7.658e-73 Identity = 153/468 (32.69%), Postives = 244/468 (52.14%), Query Frame = 3
Query: 213 QQQSNIFIFLLAIHVGCNSCSVA---------------GITRERIMDKIL---QNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLY-------QWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNY-HSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+Q NI L A +G N A ++ +DK++ Y RP + V + + + SV + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+ NG+VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W P+++ + +P+F + E CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K + + +++ D+ R+ SR+N + H +Q D AN + A IK++ + +ID SR FP F+ +N YWI Y II
Sbjct: 3 RQLVNILTALFAFFLGTNHFREAFCKDHDSRSGKHPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHY--NTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRE--SRFNFS-GYGMGHCLQMK--------------DGTAVKATPANPLPQPPKDADAIKKKFV---DRAKRIDTISRAAFPLAFLIFNIFYWITYKII 444
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glrb (glycine receptor, beta subunit [Source:MGI Symbol;Acc:MGI:95751]) HSP 1 Score: 238.039 bits (606), Expect = 1.899e-71 Identity = 140/442 (31.67%), Postives = 239/442 (54.07%), Query Frame = 3
Query: 300 IMDKILQNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTK-VETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTV------AQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQI--------------LNRNELEFCEELDILLTAQQY--------ANN--YHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
I++++L +Y RP + V+V + + + S+ + M+Y +++LRQ W D RL+ + +F+ ++ V P++ LW PDLFF N K H +T+ N L+ +F +G+VL S ++++ SC +DL +PMDTQ C+M + S+GYT D L+F W +P++L + +P+F+ + +E +CT TG+Y+C++ +F LRRQ+G Y++ + P LIV++SWL+FW++ +A AR+ LG+ ++L + ++ + ++ LP+VSY+KA+DVWLIAC++F +L+E+AV + + +K K+E D ++ N H+ T Q+ L N+ L Y NN Q + K + +ID+Y+R LFP CF+F+N YW YL
Sbjct: 59 ILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPS--DFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQL-EKIALPQFDIKKEDIEYGNCTKYYKG-TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGGNAAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKPQAKNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL 496
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra3 (glycine receptor, alpha 3 subunit [Source:MGI Symbol;Acc:MGI:95749]) HSP 1 Score: 234.187 bits (596), Expect = 3.087e-70 Identity = 142/431 (32.95%), Postives = 231/431 (53.60%), Query Frame = 3
Query: 279 AGITRERIMDKIL---QNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNL--AINRQKTHHM-QTSQILNRNELEFCE-ELDILLTAQQ----YANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
A ++ +DK++ Y RP + V + + + S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+F NG VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W P+++ + +P+F + + CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K +++R R N A +K + T + + F + L A+ N+ Q + + KID SR FP F+ +N YW+ Y I+
Sbjct: 55 APMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKH--YNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK---------ELLRFRRKRKNKTEAFALEKFYRFSDTDDEVRESRFSFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKIL 470
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra1 (glycine receptor, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:95747]) HSP 1 Score: 228.794 bits (582), Expect = 1.918e-69 Identity = 133/376 (35.37%), Postives = 213/376 (56.65%), Query Frame = 3
Query: 417 MEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQE---LSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
M+Y +++LRQ W D RL + NE+ +S + PS+ D +W PDLFF N K + H +T N L+R+ NG VLYS +IT+ +C MDL+ +PMD Q+C M + S+GYT++ L F W + +++ + + +P+F + + CT T G ++C++A F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K R + + R+N + +Q ++ + + T S E ++ Q+ KID SR FP F+ +N YWI Y I+
Sbjct: 1 MDYRVNIFLRQQWNDPRLAY---NEYPD-DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNT--GKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKDDEGGEGRFNFSAYGMGPACLQAKDGIS------VKGANNNNTTNPPPAPSKSPEEMRKLFIQR------AKKIDKISRIGFPMAFLIFNMFYWIIYKIV 358
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra1 (glycine receptor, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:95747]) HSP 1 Score: 231.106 bits (588), Expect = 2.143e-69 Identity = 134/385 (34.81%), Postives = 217/385 (56.36%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQE---LSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ S+ + M+Y +++LRQ W D RL + NE+ +S + PS+ D +W PDLFF N K + H +T N L+R+ NG VLYS +IT+ +C MDL+ +PMD Q+C M + S+GYT++ L F W + +++ + + +P+F + + CT TG ++C++A F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K R + + R+N + +Q ++ + + T S E ++ Q+ KID SR FP F+ +N YWI Y I+
Sbjct: 75 SFGSIAETTMDYRVNIFLRQQWNDPRLAY---NEYPD-DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKDDEGGEGRFNFSAYGMGPACLQAKDGIS------VKGANNNNTTNPPPAPSKSPEEMRKLFIQR------AKKIDKISRIGFPMAFLIFNMFYWIIYKIV 441
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|Q17328|GLUCB_CAEEL (Glutamate-gated chloride channel subunit beta OS=Caenorhabditis elegans OX=6239 GN=glc-2 PE=1 SV=1) HSP 1 Score: 242.276 bits (617), Expect = 6.854e-73 Identity = 149/435 (34.25%), Postives = 238/435 (54.71%), Query Frame = 3
Query: 288 TRERIMDKILQNYSLNERPIESNQT-------RVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMEL--GNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQ-ELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQY-----ANNYHSQES-AHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVSN 1544
+ + I++ +L+NY + RP +N + RV + +++L+ ++V NMEYS L R+ W+D RL ++NL F + + L P +K LW+PD FF K + H++ N +R++P+G++LYS +I++ SC M LQ YP+D QSC ++ SY +T++ + + W + P++L G +P F DCT S T TG Y CL+ + +RQ YLV + P T+IVIVSW++FW+ + + R+ LG+ TLL + T S I+ LP VSY+K +DVWL AC FV GALLE+A S YQ D VRQ + SR A Q+ R +LE ++ A+ Y + + ++E+ +++R + +KID Y+R++ P F+ +N YW+ LI+ +N
Sbjct: 28 SEQEILNALLKNYDMRVRPPPANSSTEGAVNVRVNIMIRMLS--KIDVVNMEYSIQLTFREQWIDPRLAYENLG-FYNPPAFLTVPHVKKSLWIPDTFFPTEKAAHRHLIDMENMFLRIYPDGKILYSSRISLTSSCPMRLQLYPLDYQSCNFDLVSYAHTMNDIMYEWDPSTPVQLKPGVGSDLPNFILKNYTTNADCT--SHTNTGSYGCLRMQLLFKRQFSYYLVQLYAPTTMIVIVSWVSFWIDLHSTAGRVALGVTTLLTMTTMQSAINAKLPPVSYVKVVDVWLGACQTFVFGALLEYAFVS--------YQ------DSVRQNDRSREKAARKAQR----------RREKLE-------MVDAEVYQPPCTCHTFEARETFRDKVRRYFTKPDYLPAKIDFYARFVVPLAFLAFNVIYWVSCLIMSAN 426
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|P91730|GLUCB_HAECO (Glutamate-gated chloride channel subunit beta OS=Haemonchus contortus OX=6289 PE=2 SV=1) HSP 1 Score: 241.891 bits (616), Expect = 7.449e-73 Identity = 144/431 (33.41%), Postives = 223/431 (51.74%), Query Frame = 3
Query: 273 SVAGITRERIMDKILQNYSLNERPIESNQTRVM------VFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMEL--GNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVS 1541
S G + I++++L NY + RP SN + M V + + ++ ++V NMEYS L R+ W+D RL + +L + + L P +K LW+PD FF K + H++ N +R+ P+G+VLYS +I++ SC M LQ YP+D Q C+ ++ SY +T+ + + W P++L G +P F +DCT S T TG Y+CL+ L+RQ YLV + P T+IVIVSW++FW+ + + R+ LG+ TLL + T + I+ LP VSY+K +DVWL AC FV GALLE+A S Q++ Q KS ++ ++ L + R++ T + E F + L T Y +KID Y+R+ P F+ +N YW L++VS
Sbjct: 25 STGGTQEQEILNELLSNYDMRVRPPPSNYSDPMGPVTVRVNIMIRMLSKIDVVNMEYSMQLTFREQWLDSRLAYAHLG-YHNPPKFLTVPHIKSNLWIPDTFFPTEKAAHRHLIDTDNMFLRIHPDGKVLYSSRISITSSCHMQLQLYPLDLQFCDFDLVSYAHTMKDIVYEWDPLAPVQLKPGVGSDLPNFQLTNITTNDDCT--SHTNTGSYACLRMQLTLKRQFSYYLVQLYGPTTMIVIVSWVSFWIDMHSTAGRVALGVTTLLTMTTMQAAINAKLPPVSYVKVVDVWLGACQTFVFGALLEYAFVSYQDSQRQTEQAKSRAARKAQKRRAKMEL-VEREQYQPPCTCHLYQDYEPSFRDRLRRYFTKPDYL----------------------PAKIDYYARFCVPLGFLAFNAIYWTSCLVMVS 429
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|P48167|GLRB_HUMAN (Glycine receptor subunit beta OS=Homo sapiens OX=9606 GN=GLRB PE=1 SV=1) HSP 1 Score: 243.432 bits (620), Expect = 1.246e-72 Identity = 141/443 (31.83%), Postives = 242/443 (54.63%), Query Frame = 3
Query: 300 IMDKILQNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTK-VETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTV------AQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQI--------------LNRNELEFCEELDILLTAQQY--------ANNYHSQESAHQIKR---QKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
I++++L +Y RP + V+V + + + S+ + M+Y +++LRQ W D RL+ + +F+ ++ V P++ LW PDLFF N K H +T+ N L+ +F +G+VL S ++++ SC +DL +PMDTQ C+M + S+GYT D L+F W +P++L + +P+F+ + +E +CT TG+Y+C++ +F LRRQ+G Y++ + P LIV++SWL+FW++ +A AR+ LG+ ++L + ++ + ++ LP+VSY+KA+DVWLIAC++F +L+E+AV + + +K K+E D +++ N H+ T Q+ L N+ L Y NN + A K+ K + +ID+Y+R LFP CF+F+N YW YL
Sbjct: 59 ILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPS--DFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQL-EKIALPQFDIKKEDIEYGNCTKYYKG-TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGGNVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL 497
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|Q94900|GLUCL_DROME (Glutamate-gated chloride channel OS=Drosophila melanogaster OX=7227 GN=GluClalpha PE=1 SV=2) HSP 1 Score: 241.891 bits (616), Expect = 1.415e-72 Identity = 153/433 (35.33%), Postives = 243/433 (56.12%), Query Frame = 3
Query: 294 ERIMDKILQ--NYSLNERPIESNQT------RVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQ----QKKLYQ--WKSEVRDIVRQELSRWN--LAINRQKTHHMQTSQILNRNELEFCEEL--DILLTAQQYAN---NYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
++++D+IL Y RP N T R+ +F++ +I +++ MEYS L R+ W D RL++D++ + ++ + +R+W+PDLFF N KEG+ H + PN +R+FPNG VLYS +I++ +C M+L+ YP+D Q C + + SYG+T + L F W + +P+++ N+ +P F K T+ C +S T TG YSCLK + +R+ YL+ +IP ++VIVSW++FW+ AVPAR++LG+ TLL + TQ SGI+ +LP VSY KAIDVW C+ FV GALLEFA+ + ++ + +++ K + RD+ + L + L + T M+ + L + L ++ + A + N + S+ Q R K +IDV SR FP F +N YW YL
Sbjct: 34 KKVLDQILGAGKYDARIRPSGINGTDGPAIVRINLFVR--SIMTISDIKMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTL-EKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKESMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRQCSRSK--------RIDVISRITFPLVFALFNLVYWSTYL 449
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|Q9GJS9|GLRB_BOVIN (Glycine receptor subunit beta OS=Bos taurus OX=9913 GN=GLRB PE=2 SV=1) HSP 1 Score: 241.506 bits (615), Expect = 5.218e-72 Identity = 141/445 (31.69%), Postives = 243/445 (54.61%), Query Frame = 3
Query: 300 IMDKILQNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTK-VETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQE--------LSRWNLAINRQKTHHMQTSQI--------------LNRNELEFCEELDILLTAQQY--------ANNYHSQESAHQIKR---QKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYL 1529
I++++L +Y RP + V+V + + + S+ + M+Y +++LRQ W D RL+ + +F+ ++ V P++ LW PDLFF N K H +T+ N L+ +F +G+VL S ++++ SC +DL +PMDTQ C+M + S+GYT D L+F W +P++L + +P+F+ + +E +CT TG+Y+C++ +F LRRQ+G Y++ + P LIV++SWL+FW++ +A AR+ LG+ ++L + ++ + ++ LP+VSY+KA+DVWLIAC++F +L+E+AV + K + ++E I + E +++ N H+ T Q+ L N+ L Y NN + A K+ K + +ID+Y+R LFP CF+F+N YW YL
Sbjct: 59 ILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPS--DFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQL-EKIALPQFDIKKEDIEYGNCTKYYKG-TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPK--RVEAEKARIAKAEQAVGKGGNVAKKNTVNGASTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL 497
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A183SPC0 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS6068 PE=3 SV=1) HSP 1 Score: 458.373 bits (1178), Expect = 1.674e-153 Identity = 237/427 (55.50%), Postives = 307/427 (71.90%), Query Frame = 3
Query: 276 VAGITRERIMDKILQNYSLNERPIE--SNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELE----FCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIV 1538
A R+R++ + NY +ERP E T V V MKVLAI SV+V M+Y D LRQ W D RL WD EF++F +LVSP+LK+ LWLPDLFFRNGK+GY+H MT PNYL+R++PNG VLYSQKITMRFSCQMDLQT+PMDTQ C MNIGSYGYTL++LKF W NP+EL + +QI EFN P+ T DCT S+T TG Y+CL A F L+RQLGSYLV+T+IPN LI++VSWL+F+VSV+A PAR+ LGLL+LLG+LTQAS ++ NLPRVSYIKAID+WLI I+FVI L+E+A+A T+ ++K+ W+++V IV++EL+RW A + + +MQ +EL F +LD+ LT +ES + ++ KI E ES+ID YSR+LFP+C+I YN YW+YYL+IV
Sbjct: 77 TASTLRDRLVGMLFSNYKTHERPTELLDMATVVEVNMKVLAIFSVDVRTMDYYIDALLRQTWTDPRLAWDTSKEFENFTQALVSPTLKESLWLPDLFFRNGKDGYLHKMTLPNYLLRVYPNGNVLYSQKITMRFSCQMDLQTFPMDTQHCHMNIGSYGYTLNELKFAWRPENPVELPDKLQISEFNTPSNFTTIDCTAMSSTSTGNYTCLMAKFALKRQLGSYLVTTYIPNILIIMVSWLSFYVSVDAAPARVPLGLLSLLGLLTQASSVTANLPRVSYIKAIDLWLIFSIIFVISVLVEYAIAITLLRRKRRENWRNDVESIVKEELARWCAACQQTQLANMQLKSGAVGHELSQQFAFYNDLDLFLTRTVI------EESQKKSRKTKI-PEATESEIDAYSRFLFPTCYIMYNVFYWLYYLVIV 496
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A3S5FGS1 (Uncharacterized protein OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS33396 PE=3 SV=1) HSP 1 Score: 455.677 bits (1171), Expect = 2.972e-153 Identity = 232/418 (55.50%), Postives = 306/418 (73.21%), Query Frame = 3
Query: 288 TRERIMDKILQNYSLNERPIE--SNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
TR+RI++ I +NY +ERP E + T V V M+VLAI S++V NM+Y D YLRQ+W D RL W +++EF+ + +VS LK+ +WLPDLFFRNGKEGY+H MT PNYL+R+ P+G VLYSQKITMRFSCQM+LQ +PMD Q C +NIGSYGYTL++LKF W + + L ++I EFN P +T DCTNSS T TG Y+CL A F L+RQL SYL +T+IPN LI++VSWL+FWV+V+A PAR+ LGLL+LLGILTQAS +S +LPRVSYIKAID+W+I I+FVIG L+E+A+A T+ ++K+ W +VR+IVRQEL++W A +Q +Q S L R +LEFCEEL+ LLT Q H +E +K + ES+ID YSR+LFP+CF+ YN YW+YYL++
Sbjct: 32 TRDRIVNHIFRNYLKHERPTELDNTPTEVGVNMRVLAIFSIDVRNMDYYIDAYLRQIWFDKRLAWAHIDEFRQYKQPIVSSKLKNDIWLPDLFFRNGKEGYLHTMTVPNYLLRVMPDGNVLYSQKITMRFSCQMELQNFPMDMQVCGLNIGSYGYTLNELKFVWHE-EKVNLSGRMRISEFNTPETFDTFDCTNSSKTSTGNYTCLNATFKLKRQLSSYLATTYIPNILIIMVSWLSFWVNVDAAPARVPLGLLSLLGILTQASSVSNSLPRVSYIKAIDIWMIFSIIFVIGVLVEYALALTMLRRKRADTWHRDVREIVRQELAKWCTACQQQHLVQLQNSHQLTRGQLEFCEELEALLTNQVID---HQKEKNKAVKP----TTTTESEIDSYSRFLFPACFLLYNCFYWLYYLVL 441
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A0R3UFU9 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS6030 PE=3 SV=1) HSP 1 Score: 457.603 bits (1176), Expect = 4.617e-153 Identity = 224/429 (52.21%), Postives = 312/429 (72.73%), Query Frame = 3
Query: 291 RERIMDKILQNYSLNERPIE--SNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTS-QILNRNELEFCEELDILLTAQQYANNYHSQESAHQIK--------RQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVSN 1544
RE I++KI NY +ERP E T V V MK+ +I S++V M+Y D LRQ WVD RL WD + E ++F +VSP +K++LWLPDLFFRNGKEGY+H MT PNYL+R++PNG+VLYSQKITMRF+CQMDLQT+PMD Q C++NIGSYGYTL +LKF WS+T+P+EL + +Q+ EFNAP T DCT+ ++T TG Y+CL A F + RQLGSYLV+T+IPN LI++VSWL+FWVSV+A PAR+ LGL++LLGILTQAS + NLPRVSYIKA+D+WLI I+FVI L+E+A+A + ++ + QWK ++R IVR+EL+RW A +++ M+ + ++ + + ++ +++ ++T + YH + A K R K L+ + +S ID YSR+LFP C++ YN CYW+YYL++V +
Sbjct: 84 REDILEKIFLNYKTHERPTELLDTSTVVRVNMKIQSIFSIDVRTMDYYVDALLRQAWVDPRLAWDKMPEHRNFTQPIVSPKMKNQLWLPDLFFRNGKEGYLHKMTLPNYLLRVYPNGQVLYSQKITMRFACQMDLQTFPMDVQECDINIGSYGYTLSELKFMWSETSPIELNDEMQLSEFNAPKHFATFDCTSQASTSTGNYTCLLAKFSIARQLGSYLVTTYIPNILIIMVSWLSFWVSVDAAPARVPLGLMSLLGILTQASSVGSNLPRVSYIKALDLWLIFSIIFVISVLVEYALAISYLRKTRKCQWKDDLRAIVREELARWCSACQQKELESMRAAGAVVPKYQADYYTQMEAMITFRDAIEQYHKKRDARSGKGGISKSTARIKTLTGVTDSVIDGYSRFLFPLCYLAYNICYWLYYLVLVKH 512
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A0R3TPG4 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS9358 PE=3 SV=1) HSP 1 Score: 456.833 bits (1174), Expect = 7.853e-153 Identity = 227/424 (53.54%), Postives = 312/424 (73.58%), Query Frame = 3
Query: 291 RERIMDKILQNYSLNERPIE--SNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILN-RNELEFCEELDILLTAQQYANNYHSQESAHQI-----KRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIV 1538
R+ I +KI NY NERP E T VMV MK+ +I S++V M+Y D LRQ WVD RL WDN+ E K+F LVSP++K+ LWLPDLFFRNGKEGY+H MT PNYL+R++PNG+VLYSQKITMRF+CQMDLQT+PMD Q C++NIGSYGYTL +LKF WS++ P+EL ++Q+ EFN P + T+DCT++S+T TG Y+CL A F + R+LGSYLV+T+IPN LI++VSWL+FWVS++A PAR+ LGL++LLGILTQAS + NLPRVSYIKAID+WLI I+FVI L+E+A+A T ++ + QW+S+VR IVR+EL++W A +++ ++ + L N ++ +++ ++ + YH + A +R K+++ + ES ID YSR+LFP C++ YN CYW+YYL+IV
Sbjct: 85 RDAIKEKIFTNYKSNERPTEQLDTSTIVMVNMKIQSIFSIDVRTMDYYVDALLRQAWVDPRLAWDNIPEHKNFTQPLVSPNMKNILWLPDLFFRNGKEGYLHKMTLPNYLLRVYPNGQVLYSQKITMRFACQMDLQTFPMDVQECDINIGSYGYTLSELKFVWSESAPIELNKDMQLSEFNTPKEFFTSDCTSASSTSTGNYTCLLAKFSIARRLGSYLVTTYIPNILIIMVSWLSFWVSIDAAPARVPLGLMSLLGILTQASSMGSNLPRVSYIKAIDLWLIFSIIFVISVLVEYALAITYLRKTRKGQWRSDVRAIVREELAKWCTACQQRELKSLKAAGALAPGNHADYYTQMEAMVAFRDVVELYHKRRLASNGHNGINERIKVITGVTESVIDGYSRFLFPLCYLVYNACYWLYYLVIV 508
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A0R3SRH4 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS7771 PE=3 SV=1) HSP 1 Score: 456.447 bits (1173), Expect = 8.152e-153 Identity = 234/424 (55.19%), Postives = 303/424 (71.46%), Query Frame = 3
Query: 291 RERIMDKILQNYSLNERPIESNQ--TRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINR------QKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIV 1538
R+R+++ + + Y NERP E T V V +KVLAI SV+V M+Y D LRQ WVD RL WD+ +FK++ LVSP+LKD +W+PDLFFRNGK+GY+H MT PN+L+R+ PNGEVLYSQKITMRFSCQMDL T+PMDTQ C MNIGSYGYTL +LKF+W + P+EL NN+Q+ EFN PT T DCT S+T TG Y+CL A F L+RQLGSYLV+T+IPN LI++VSWL+F+VSV+A PAR+ LGLL+LLG+LTQAS I+GNLPRVSYIKAID+WLI I+FVIG L+E+A+A T+ +QKK W+ +V IV++EL+RW A + Q + M+ Q + +L + +LD LT + + R + + ES+ID YSR+LFP+C+I YN YW YYL IV
Sbjct: 78 RDRLVNMLFKTYRTNERPTEKLDIPTEVSVNIKVLAIFSVDVRTMDYYIDALLRQTWVDPRLAWDHDEDFKNYTQPLVSPTLKDNIWIPDLFFRNGKDGYLHKMTLPNFLLRVHPNGEVLYSQKITMRFSCQMDLATFPMDTQYCHMNIGSYGYTLSELKFFWREKEPVELQNNLQLSEFNTPTNFTTLDCTAQSSTATGNYTCLIAEFSLKRQLGSYLVTTYIPNILIIMVSWLSFYVSVDAAPARVPLGLLSLLGLLTQASSITGNLPRVSYIKAIDLWLIFSIIFVIGVLVEYAIAITMLRQKKKETWRGDVETIVKEELTRWLAACEQGQMASIQGSGGMRGDQAFIQQQLAYFNDLDAFLTQSVVEEARAKKGPGGKKNRIPVAT---ESEIDAYSRFLFPTCYIMYNIFYWTYYLAIV 498
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra3 (glycine receptor, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-020402-1]) HSP 1 Score: 243.047 bits (619), Expect = 6.105e-74 Identity = 135/388 (34.79%), Postives = 220/388 (56.70%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKK------LYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K + H +T N L+R+F NG VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W P+++ + + +P+F + + CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K + KS + VR+ + + T T+ + + Q + +S +++ KI + KID SR FP F+F+N YW+ Y I+
Sbjct: 79 SFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQANGPVQVADGLTLPQFILKDESDLRYCTKH--YNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRKKSTKEEEVRESCLSFTANAGKDGTMTKPTNNAASTPK------------GQPTPTVPQAGKSTEEMR--KIFID-RAKKIDTVSRAGFPLAFLFFNIFYWVLYKIL 445
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:103026517]) HSP 1 Score: 239.965 bits (611), Expect = 8.040e-73 Identity = 141/424 (33.25%), Postives = 237/424 (55.90%), Query Frame = 3
Query: 294 ERIMDKILQNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQ-KKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEE------SKIDVYSRYLFPSCFIFYNFCYWIYYLIIVS 1541
+++M K+ Y RP + V + + + S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+ NG VLYS +IT+ +C MDL+ +PMD Q+C M + S+GYT++ L F W + +++ + + +P+F + + CT T G ++C++A F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + +A+Q K+L +++ R + E + + M + + ++ + NN ++ S+ I +K + E+ + +ID SR FP F+ +N YWI Y II S
Sbjct: 42 DKLMGKV-SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNT--GKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFQRRRRHLKEDEAGEGRFSF---AAYGMGPACLQAKDGMAI------------KGNNNNAPTSS--IPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWIIYKIIRS 441
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1]) HSP 1 Score: 238.81 bits (608), Expect = 1.603e-72 Identity = 137/384 (35.68%), Postives = 221/384 (57.55%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSL-VSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVA-QQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ SV + M+Y +++LRQ W D RL + ++ + SL + PS+ D +W PDLFF N K H +T N L+R+ +G VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W P+++ + +P+F + E CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V+ QQK+ + K + +++EL R+ H + ++ ++ +A A S + R+K + + +ID SR FP F+ +N YWI Y II
Sbjct: 69 SFGSVTETTMDYRVNIFLRQKWNDPRLAYS-----EYPDPSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKDGTVLYSIRLTLILSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLDEGPVQVAEGLTLPQFIMREEKELGYCTKHY--NTGKFTCIEVKFKLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAGVNFVSRQQKEFLRLKRRQKRNLKEEL--------REGRFHFSGYSM-----APCMKDGTVVKSATANAIQQPSALRDAEHNRKKFVDRAK--RIDTISRAAFPLAFLIFNIFYWITYKII 430
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:103026517]) HSP 1 Score: 238.81 bits (608), Expect = 2.604e-72 Identity = 135/391 (34.53%), Postives = 224/391 (57.29%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQ-KKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEE------SKIDVYSRYLFPSCFIFYNFCYWIYYLIIVS 1541
+ S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+ NG VLYS +IT+ +C MDL+ +PMD Q+C M + S+GYT++ L F W + +++ + + +P+F + + CT T G ++C++A F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + +A+Q K+L +++ R + E + + M + + ++ + NN ++ S+ I +K + E+ + +ID SR FP F+ +N YWI Y II S
Sbjct: 87 SFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNT--GKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFQRRRRHLKEDEAGEGRFSF---AAYGMGPACLQAKDGMAI------------KGNNNNAPTSS--IPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWIIYKIIRS 454
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra3 (glycine receptor, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-020402-1]) HSP 1 Score: 238.81 bits (608), Expect = 5.882e-72 Identity = 143/412 (34.71%), Postives = 226/412 (54.85%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDI--------VRQELSRWNLAINRQKTHHM------QTSQILNRNE------LEFCEELDILLTAQQYANNYHS----QESAHQIKRQKILSEIEE------SKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K + H +T N L+R+F NG VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W P+++ + + +P+F + + CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K R +ELS ++N ++ Q S+ +R E L F T + NN S Q + + K E+ + KID SR FP F+F+N YW+ Y I+
Sbjct: 79 SFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQANGPVQVADGLTLPQFILKDESDLRYCTKH--YNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRKKSTKLHDRSFEEELSESLQSVNGLRSADPVYGSMDQMSESNDREEEVRESCLSFTANAGKDGTMTKPTNNAASTPKGQPTPTVPQAGKSTEEMRKIFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKIL 484
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1]) HSP 1 Score: 230.72 bits (587), Expect = 1.362e-70 Identity = 132/385 (34.29%), Postives = 212/385 (55.06%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNR------NELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYY 1526
+ S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+F +G VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W Q +++ + +P+F + + CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K R + +L+ L N + I N NE ++ + + IK++ + +ID SR FP F+ +N YWI Y
Sbjct: 16 SFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKDGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWKQEGAVQVAEGLTLPQFVLKDEKDLVYCTKHY--NTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKELLRIRRRRQRNQIDLTSLILICNIFTYFINSSVPIFNMFKRVEGNERALTKDSVSVKGVNATNAAPAPAPTQDAIKKKFV---DRAKRIDTISRAAFPLAFLIFNIFYWIIY 391
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008467.1 (pep scaffold:Pmarinus_7.0:GL477211:8305:20106:1 gene:ENSPMAG00000007648.1 transcript:ENSPMAT00000008467.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 225.713 bits (574), Expect = 5.391e-68 Identity = 133/438 (30.37%), Postives = 231/438 (52.74%), Query Frame = 3
Query: 261 CNSCSVAGITRERIMDKIL---QNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLN-EFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVR----DIVRQELSRWNLAINRQKTHHMQ-TSQILNRNELEFCEELD--ILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIV 1538
+S + ++ ++DK+L Y+ RP V + + + S+ + +Y +YLRQ W D RL + + H + S + +W PDLFF N K + H +T N ++R+ NG V Y+ ++T+ SC MDL +PMDTQ C M + S+GYT + F+W+ P+ L + +P+F K+ T CT T TG ++C+ A F L R++G YL+ ++P+ LIVI+SW++FW+++EA PAR+ LG+ T+L + TQ++G +LP+VSYIKA+D+W+ C++FV ALLE+A + ++Q + + K D++ + W + + T I N L + +++ + + QE+ +++++ + ID SR FP F+ +N YW + +++
Sbjct: 32 ADSTTGPNLSPSEVLDKLLGPSSGYNHRVRPNFGGPAVNVSCGVFIRSFGSIQEATSDYRMTVYLRQRWTDPRLAYSHYPVPLLHLDQSNIK-----HIWKPDLFFDNEKSAHFHEITTDNKMLRIANNGVVDYAMRLTLTLSCPMDLHNFPMDTQMCSMYLESFGYTTADIVFHWNGPTPVSLFEGLTLPQFVLSNKISTGSCTK--TYSTGSFTCIFAKFTLHREMGFYLIQLYVPSILIVILSWVSFWINMEAAPARVALGITTVLTLTTQSTGARASLPKVSYIKAMDIWMATCLLFVFAALLEYAAVNVTSRQSQGFMKKGRGNQKPIDLLVHKKMFWKFLVAENDNDLLYFTITIFTLNGLLPVSDSKKPVIVCIKPLLS---LQETKEKMRKKYVAC---AQTIDNISRLFFPISFLIFNVVYWFAFKVML 456
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra4a (glycine receptor, alpha 4a [Source:ZFIN;Acc:ZDB-GENE-010410-3]) HSP 1 Score: 209.534 bits (532), Expect = 6.220e-62 Identity = 137/425 (32.24%), Postives = 212/425 (49.88%), Query Frame = 3
Query: 303 MDKILQN--YSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFK--HFNSSLV--SPSLKDRLWLPDLFFRNGKEGYVH---IMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSE-------IEESKIDVYSRYLFPSCFIFYNFCYWIYY 1526
MD ++++ Y RP ++ V + V V + M+YS +++LRQ W D R+ LN K +N+ + S D +W PDLFF N K ++T Y+ ++++ +C M L+ YPMD Q C + + SYGYT + L F W+ T P+ G V P+F + +CT T G +SC+KA F L R +G YL+ +IP+ L+VI+SWL+FW++VEA PAR+ LG+ T+L + TQ + + LP+VSYIKAIDVW+ AC VFV ALLEFA + ++ + + + E L I ++ H S + R E D + + +S+ + R + E + +ID SR +FP+ F+ +N YW+ Y
Sbjct: 47 MDNVIRDTGYDSRMRPNVDGPPVVVNCSILVKGFGPVEEATMDYSINIFLRQTWNDPRI----LNVLKSIEYNTDFLDLGNSFVDSVWKPDLFFENEKSAAFQMYQLVTGFKYMYTFAMWITCFLCFRLSLVLACPMSLEVYPMDAQYCSIYLESYGYTTNDLIFQWNDTEPVSFGAGVSTPKFTLSNETFLGECTKEYTY--GTFSCVKATFFLDRDMGYYLIQVYIPSCLLVIISWLSFWLNVEAAPARVGLGITTILTVTTQMTSANAALPKVSYIKAIDVWMGACQVFVFSALLEFAAVNMATRRHGISPSHHDGDHGTKGE-----LPIEWKRHRHANVSSV--RRPQRHRPERDCRSQGKPGVFHTNSRRDENNATRVHVSDEEWRYQSLLHARRIDYISRVIFPTVFMIFNIFYWVIY 458
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002305.1 (pep scaffold:Pmarinus_7.0:GL478144:76380:93696:1 gene:ENSPMAG00000002075.1 transcript:ENSPMAT00000002305.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 201.06 bits (510), Expect = 6.580e-59 Identity = 125/395 (31.65%), Postives = 205/395 (51.90%), Query Frame = 3
Query: 384 VLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLV--SPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNL---------AINRQKT---HHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYY 1526
V + + + M+Y +YL+Q W+D R+ +++ H+ + + + D +W PDLFF N K H + ++ N + +S +++ +C M+L+ YP+DTQ C +N+ S+GYT L F W + P+ + N+ P+F E DC S TG +SC+ A F L R +G YL+ + P+ L+VI+SWL+FW+SVE+ PAR++LG+ T+L + TQ + + LP++SYIKA+DVW+ AC VFV ALLE V S Q + K+E RD ++ + W+L NR ++ +T+ ++N+ F + + + R++ L + +ID SR LFP F+ + YW Y
Sbjct: 65 VKSFGPIEENTMDYMMLIYLQQSWIDSRI--ESIYSAGHYQKDFLDLANNYIDTVWTPDLFFENEKSAAFHEIHCRFSIIVHATNNKTCFSLVLSLTLACPMNLEYYPLDTQECRINLESFGYTTQDLIFQWDENEPLVVATNLYTPKFKLSNHTELGDC--SKEYLTGTHSCINATFYLHRDMGYYLIQVYFPSCLLVIISWLSFWLSVESTPARVSLGITTILTVTTQMTSANAALPKMSYIKAMDVWMAACQVFVFAALLESTVVSVTKQH--VVSGKAETRD--QKNNNVWDLFFNPLYDVVGYNRSRSLGRAAKRTTSVVNQPHGWFISQ----------------PTDSDGMARERSL--VRSRQIDYISRVLFPLAFVIFLTIYWFSY 433
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676]) HSP 1 Score: 196.052 bits (497), Expect = 6.641e-59 Identity = 99/278 (35.61%), Postives = 168/278 (60.43%), Query Frame = 3
Query: 285 ITRERIMDKILQNYSLNERPIESN----QTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNE-FKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVS 1103
I +DK+L S + I N V + + + S+ + M+Y ++LRQ W+D RL + + E + + S + +W PDLFF N K Y H +T N ++R+F NG VL++ ++T+ SC MDL+ +PMDTQ C M + S+GYT+ L F+W + P+ + + +P+F +K++T+ C ++ TG +SC+ A F+L R++G YL+ ++P+ LIVI+SW++FW+++EA PAR+ LG+ T+L + TQ++G +LP+V+
Sbjct: 1 IAPTEFLDKLLGPTSGYDHRIRPNFGGPTVNVNCSVYIKSFGSIEETTMDYQVTIFLRQKWIDPRLTYSHYPEPYLDLDQSNIQ-----YIWRPDLFFDNEKSAYFHEVTTDNKMLRIFKNGLVLFTVRLTLTLSCPMDLRNFPMDTQMCYMFLESFGYTMADLSFHWDEEEPVIISKELVLPQFVLSSKIDTDSCDKLYSSGTGHFSCISARFVLHREMGFYLIQLYVPSALIVIISWVSFWINMEAAPARVALGITTVLTMTTQSTGARASLPKVT 273
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO37555 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFG6]) HSP 1 Score: 194.897 bits (494), Expect = 1.662e-56 Identity = 124/426 (29.11%), Postives = 225/426 (52.82%), Query Frame = 3
Query: 300 IMDKILQNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSL-VSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCE------------ELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
++D ++Q Y RP + V V VL+I+++NV +M+Y D +LRQLW D RL+ F+ +L +S ++ D++W+PD +F N K H +T N ++ + P+G V Y+ ++T++ SC M+L+ +P D Q+C ++I SYGY+ D +++ W + + N +I + + N + + G +S L A F RR+ G +++ + P LIVI+SW++F + E+ ARI LG+ ++L I T + ++ ++P+VSY+KA+D +LI C +FV LLE+ + +++ ++K ++ + + + +R H M S + F E D++L +++ ++Y R K + I+ ID ++R LFP FI +N Y+I + I
Sbjct: 9 LLDNLIQGYDPRLRPDFGGDPVTVTVGFWVLSIDAINVIDMDYRMDFFLRQLWRDPRLK-------HRFDDTLALSNTMLDKIWVPDTYFVNSKMSKFHSVTTINKMLSISPDGLVHYNSRVTVKASCAMNLRMFPKDVQNCNIDIESYGYSADNVQYQWENRSDNGIAVNKKIRDMPQYNLSDINVSRHFTMYVAGNWSGLTATFRFRRRSGYFIIHIYAPCALIVILSWISFCIPPESTAARIALGITSVLTITTILNMLNNSMPKVSYVKAVDWYLIGCFLFVFAVLLEYTFVLYI-DNEEVTEYKKDLVNYSSESVK------HRSPAHAMNGSIPNGYSPAVFSEHGKKCGHNCHHAHHDVVLKREKHKSSYEQLGGCR--PRLKFPAVIDTECIDEFARVLFPFIFIAFNVIYFIVFFFI 418
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO35410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK4]) HSP 1 Score: 188.348 bits (477), Expect = 3.316e-55 Identity = 100/300 (33.33%), Postives = 182/300 (60.67%), Query Frame = 3
Query: 300 IMDKILQNYSLNERPIESNQTRVM-VFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQ----TNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVAS 1184
++ +L+ Y RP + V+ V M V I ++ NM+++ D+YLRQ W D RL+++ +S + ++W+P +F K+ Y H +T NYL+++ P+G + YS ++T+ SC++DL+ +P DTQSC +++ SYGY + + W++ T+ + + +++++P+F + + + G +S L A F ++R++G +L+ T+IP+T+IVI+SW++FW+ E PAR+ LG+ T+L + T S NLP+VSY+KAID +L+ C++FV G++LE+ +
Sbjct: 25 VLKNLLEGYDRRIRPGSKGEPVVVYVDMYVSNIWAMQEMNMDFTIDIYLRQYWRDERLQFETQTPGAMLT---LSSDINKQIWVPSTYFLATKKAYFHDVTTDNYLLQVKPDGSLFYSIRLTITTSCRLDLRDFPHDTQSCSLSLESYGYQSTDVLYVWNERLDNTSAIYIHDDLELPQFEV---LGVSRSAKMNKYNIGNHSSLVANFRMKRRIGYFLIDTYIPSTIIVIISWISFWIDPETAPARVALGITTVLTMTTLISSARANLPKVSYVKAIDWYLLLCLIFVFGSILEYTCVT 318
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO30047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1W8]) HSP 1 Score: 182.956 bits (463), Expect = 2.103e-53 Identity = 110/303 (36.30%), Postives = 183/303 (60.40%), Query Frame = 3
Query: 297 RIMDKIL--QNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELG----NNVQIPEFN-APTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVA 1181
RI+D IL + Y RP + V V VL+I+++NV +M+Y+ D++LRQ WVD RL D LN + +S ++ D++WLPD +F N K+G H +TK N ++ + P+G+V Y+ ++T+R SC M+L+ +PMDTQ C + + SYGY+ D + F W + LG + +P++ AP + + C G +S +KALF R +++ + P LIV+VSW++F + E PARITLG+ ++L ++T + ++ ++P+V+Y+K ID +LI C +FV L+E+++
Sbjct: 3 RILDSILTAEKYDKRLRPNYGAGPVIVTVGFWVLSIDTINVVDMDYTLDIFLRQSWVDERLSHD-LN-----TTMFLSNTVMDKIWLPDSYFVNAKQGSFHKVTKDNMMVMIQPDGQVQYNARVTIRASCPMNLRKFPMDTQHCPLTLESYGYSSDHIVFKWEIEDGDGLGFVPESLKMLPQYKLAPNEPRSELC----FVIPGNWSGIKALFTFERMYSYFVIHVYGPCALIVVVSWVSFLLPKEQAPARITLGVTSVLTVVTILNMLNNSMPKVNYVKTIDKYLIGCFLFVFATLVEYSLV 295
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO34692 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNK5]) HSP 1 Score: 177.178 bits (448), Expect = 1.560e-51 Identity = 97/263 (36.88%), Postives = 163/263 (61.98%), Query Frame = 3
Query: 423 YSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLK--DRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNP----MELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVA 1193
++ D+YLRQ W D RL +D + N+ +++ + + D +W+P +F N K+ Y H +T NYL+ + PNG+V YS ++T+ +C++ LQ +P D Q CEM + SYGY + + W+ N + + ++++P+F T V+ + TN G +S L A F R+LG Y++ T+IP+ L V +SW +FW+S ++ PAR+ LG+ T+L ++T ++ LP+VSY KAID +L+ C+V+V GAL+E+A+ + A
Sbjct: 2 FTIDMYLRQYWRDPRLIFDPVP----VNTDVLTLNRQTIDEIWIPSTYFFNAKKAYFHDVTTENYLLMIKPNGDVFYSVRLTITMACKLTLQMFPHDVQVCEMMLESYGYQATDVYYRWNSRNSTGDVVYISEDLEMPQFKI-TNVKLEERTN--IYNIGPHSALIAKFTFHRRLGYYMIQTYIPSMLTVTISWFSFWISPDSPPARVGLGITTVLTMITISNSARAPLPKVSYTKAIDWFLLMCLVYVFGALMEYAIVNFYA 257
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO40478 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S763]) HSP 1 Score: 175.252 bits (443), Expect = 7.474e-51 Identity = 97/273 (35.53%), Postives = 166/273 (60.81%), Query Frame = 3
Query: 378 MKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSL-VSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQ---TNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVAS 1184
M VL I ++ ++ME+ + RQ W D RL +D + +N L ++ + D +W+PD++F N K G H +TK N ++R++P+G V +S +++M SC M L +YPMD Q+C+++ S+ Y +L F W++ +++ + +QIP+F T++ N + TG YS L LF R +G +L+ T+IP LIV++SW+ FW++ + PARI LG+ T+L + T + +LP+VSY+K+I+ +LI C ++V +L+E+ S
Sbjct: 12 MFVLDIGDISEADMEFRVMFFYRQYWQDTRLAYD----YTGYNKRLALNARMVDYMWIPDIYFVNEKSGIKHDLTKQNEVVRVWPDGRVFHSIRLSMTASCPMKLHSYPMDKQTCKLSFESFSYPSTELIFKWNKNRGNKEVQVSDELQIPQFILTEYKTTSEFANFT---TGSYSRLTVLFRFERSIGFFLIQTYIPAYLIVMLSWIAFWINHTSTPARIGLGITTVLTMTTLTNSARASLPKVSYVKSIEWFLIMCFLYVFMSLVEYGCVS 277
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: ENSORLT00000025211.2 (glycine receptor subunit alpha-3 [Source:NCBI gene;Acc:101174559]) HSP 1 Score: 245.743 bits (626), Expect = 5.186e-75 Identity = 140/424 (33.02%), Postives = 237/424 (55.90%), Query Frame = 3
Query: 279 AGITRERIMDKIL---QNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQ-KKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
A ++ +DK++ Y RP + V + + + S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K + H +T N L+R+F NG VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W + P+++ + +P+F + + CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K+L +++ + ++E+ L T M ++ ++++ + A N + + + L KID SR FP F+F+N YW+ Y I+
Sbjct: 31 APMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYAEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFQWQENGPVQVAEGLTLPQFILKDESDLRYCTKH--YNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRH-KSKTKEEVGESKLT----STAVMTSTPSISKDSKASVNNA-VAPAANTTQNAPAAGGGGRSTEEMRKLFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKIL 442
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra4a (glycine receptor subunit alpha-4-like [Source:NCBI gene;Acc:101156095]) HSP 1 Score: 241.506 bits (615), Expect = 2.720e-73 Identity = 147/450 (32.67%), Postives = 240/450 (53.33%), Query Frame = 3
Query: 231 FIFLLAIHVGCNSC-------SVAG--ITRERIMDKIL---QNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLY--QWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
F F + +SC S AG ++ +DK++ Y RP + V + + + S+ + M+Y +++LRQ W D RL + + NS + PS+ D +W PDLFF N K H +T N L+R+F +G VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W NP+++ +++ +P+F + + CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q K + K + + + +EL R + + Q + LE Y S+ + KR ID SR +FP F+ +N YW+ Y ++
Sbjct: 14 FCFFQGSFIRLSSCKEEIKPASRAGPQLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQNWNDPRLAYSEYPD----NSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQDGSVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLIFEWLSDNPVQVADDLTLPQFVLKEEKDLGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFIRLRKKQRQQRIEEELVRESRGFYFRGYGLGHCLQTKDGAPLEGATVFSPPPPMTMYDGEVFSKRFVDRAKR-----------IDTISRAVFPLSFLIFNIFYWLTYKVL 446
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557]) HSP 1 Score: 236.884 bits (603), Expect = 7.934e-72 Identity = 142/421 (33.73%), Postives = 233/421 (55.34%), Query Frame = 3
Query: 294 ERIMDKILQNYSLNERP-IESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQ-KKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESA---HQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVS 1541
+++M K+ Y RP + V + + + S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+ NG VLYS +IT+ +C MDL+ +PMD Q+C M + S+GYT++ L F W + +++ + + +P+F + + CT TG ++C++A F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + +A+Q K+L +++ R + E + M + + ++ + NN ++ SA I+ K L +ID SR FP F+ +N YWI Y II S
Sbjct: 32 DKLMGKV-SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFRRRRRHMKEDETGDGRFGF---PGYGMGPACLQAKDGMAI------------KGNNNNAPTSAAPEKSIEEMKKLFIGRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRS 430
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra2 (glycine receptor alpha 2 [Source:NCBI gene;Acc:101169154]) HSP 1 Score: 236.113 bits (601), Expect = 2.858e-71 Identity = 135/395 (34.18%), Postives = 228/395 (57.72%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSL-VSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLY----------QWKSEVRDIVRQELSRWNLA--INRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLII 1535
+ S+ + M+Y +++LRQ W D RL + K+ +SSL + PS+ D +W PDLFF N K H +T N L+R+F +G VLYS ++T+ SC MDL+ +PMD Q+C M + S+GYT++ L F W + +++ + +P+F + E CT TG ++C++ F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + V++Q+K + Q + ++RD R + +N++ ++ + + ++ + + +++D + R+K + + +ID SR FP F+ +N YWI Y II
Sbjct: 82 SFGSIAETTMDYRVNIFLRQKWNDPRLAYS-----KYPDSSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKDGTVLYSIRLTLILSCPMDLKNFPMDVQTCTMQLESFGYTMNDLVFEWLEYGAVQVSEGLTLPQFIMKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAGVNFVSRQQKEFLRLRRRQRRNQKEEDMRD-GRFNYASYNISQCLSTKNSSAVKNTTPAPNPQPPTPKDIDAM--------------------RKKFVDRAK--RIDTISRAAFPLAFLIFNVFYWITYKII 446
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557]) HSP 1 Score: 235.343 bits (599), Expect = 3.764e-71 Identity = 136/388 (35.05%), Postives = 220/388 (56.70%), Query Frame = 3
Query: 390 AINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQ-KKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESA---HQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVS 1541
+ S+ + M+Y +++LRQ W D RL + + +S + PS+ D +W PDLFF N K H +T N L+R+ NG VLYS +IT+ +C MDL+ +PMD Q+C M + S+GYT++ L F W + +++ + + +P+F + + CT TG ++C++A F L RQ+G YL+ +IP+ LIVI+SW++FW++++A PAR+ LG+ T+L + TQ+SG +LP+VSY+KAID+W+ C++FV ALLE+A + +A+Q K+L +++ R + E + M + + ++ + NN ++ SA I+ K L +ID SR FP F+ +N YWI Y II S
Sbjct: 77 SFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFRRRRRHMKEDETGDGRFGF---PGYGMGPACLQAKDGMAI------------KGNNNNAPTSAAPEKSIEEMKKLFIGRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRS 443
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000032691.1 (SMESG000032691.1) HSP 1 Score: 899.042 bits (2322), Expect = 0.000e+0 Identity = 447/448 (99.78%), Postives = 447/448 (99.78%), Query Frame = 3
Query: 201 MTIKQQQSNIFIFLLAIHVGCNSCSVAGITRERIMDKILQNYSLNERPIESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVSN 1544
MTIKQQQSNIFIFLLAIHVGCNSCSVAGITRERIMDKILQNYSLNERPIESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVD RLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARITLGLLTLLGILTQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVSN
Sbjct: 1 MTIKQQQSNIFIFLLAIHVGCNSCSVAGITRERIMDKILQNYSLNERPIESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDARLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARITLGLLTLLGILTQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVSN 448
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000041885.1 (SMESG000041885.1) HSP 1 Score: 523.087 bits (1346), Expect = 0.000e+0 Identity = 261/415 (62.89%), Postives = 327/415 (78.80%), Query Frame = 3
Query: 294 ERIMDKILQNYSLNERPIESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIV 1538
ERI+DK + Y +ERP E QT V+V+MKVLAINSV+V+ MEYSTD+YLRQ W D RL W+NL EF+ FN+++VSPSLK LWLPDLFFRNGKEGYVH MT PNYLMRL PNG +LYSQKITMRFSC+M+LQT+PMD+Q C M+IGSYGYTLD+LKF W + +P+ + +QI EFN+P +V T DCTN S+T TG Y+CLKA F+L+RQLGSYLVSTF+P+ LIV+VSWLNFW++V++VPAR+TLGL+TLLG+LTQA+GIS LPRVSYIKAIDVW+IACI+FVIGALLE+ VAS +A++KK W+ +VR+IVR EL+RW A RQ+ H+Q L+RN LEFC EL+ LL AH+ K+ + E+S ID YSR+LFP+CF+ YN YW+YYL++V
Sbjct: 37 ERIVDK--KRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARVTLGLVTLLGMLTQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHAL--------DAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLV 441
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000041886.1 (SMESG000041886.1) HSP 1 Score: 498.049 bits (1281), Expect = 1.488e-173 Identity = 250/444 (56.31%), Postives = 330/444 (74.32%), Query Frame = 3
Query: 222 SNIFIFLLAIHVGCNSCSVAGITRERIMDKILQNYSLNERPIESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWN---LAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILS-EIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVS 1541
N+ ++L + + +E+I + I NY+ + P+ SNQTRVMV+MK+L+I+SVNVSNM+YSTDLYLRQ WVD RLRWD+L + HFNS++V+P+LKD++WLPDLFFRNGK GYVH MT+ NYLMRL P GE+LYSQKITM FSCQMDL+T+PMDTQ CEM+IGSYGYT+D+LKF+W ++P+ +G VQIPEFN+PTKV+T DCT++S T TG Y+CLK +F L+RQLGSYLVSTFIPN+LIV+VSWLNFW+ V+A PAR+TLGLLTLLGILTQASGI+ LPRVSYIKAIDVW+IACI+FVIGAL+E+ +AST Q +K QW +V +V +E+ R + L +N N+ F + ++ + N ++ +K+ + S EI +S +D YSR++FP+CFI YN +W YYL++V+
Sbjct: 8 GNLGTYILVLMLFVAEIQTKNNDQEKIFEIIFTNYTNTDLPLHSNQTRVMVYMKLLSIDSVNVSNMDYSTDLYLRQQWVDPRLRWDDLQDLNHFNSNIVTPALKDKVWLPDLFFRNGKFGYVHKMTRSNYLMRLNPKGEILYSQKITMGFSCQMDLKTFPMDTQHCEMDIGSYGYTIDELKFFWRASDPINIGKTVQIPEFNSPTKVDTLDCTSASKTTTGSYTCLKVVFTLKRQLGSYLVSTFIPNSLIVVVSWLNFWIRVDAAPARVTLGLLTLLGILTQASGITKTLPRVSYIKAIDVWMIACIMFVIGALIEYILASTAMQNRKTKQWNQDVNLVVHREIERMDRLFLKVNLSVV-----------NDETFTNDFRSMVKEK---NVLKYRDKVRFMKKNRPFSVEITDSDVDRYSRFIFPACFILYNVFFWYYYLVLVN 437
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000037124.1 (SMESG000037124.1) HSP 1 Score: 485.723 bits (1249), Expect = 1.973e-168 Identity = 256/436 (58.72%), Postives = 332/436 (76.15%), Query Frame = 3
Query: 291 RERIMDKILQNYSLNERPIESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWN-LAINRQKT------HHMQTSQILNRNEL-----------EFCEELDILLTAQ--QYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIV 1538
RE+I + I + Y NERP E+ QT V V+MKVLAINSV+V MEYSTD+YLRQ W+D RL WD++ +F+ +N++LVSP K+++WLPDLFFRNGK+GYVH MT PNYL+RL PNGEVLYSQKITM+FSCQMDLQT+PMDTQ C M+IGSYGYTLDQLKF W PM L +QIPEFN PT V+T DC+ S+T TG Y+C+KA F L+RQLGSYL ST+IPN LIV+VSWLNFWVS++AVPARITLGLLTLLGILTQA+G+S NLPRVSYIKAIDVW+IACI+FVIGAL+EFA+AS ++++ K W+ +V++IV QEL +W+ +A+ +Q++ H M T + + L EF +L++ LTAQ + + N ++S + + + +I +S+ID YS++LFP+ F+ YN YW+YYLI+V
Sbjct: 14 REQIQNHIFKGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARITLGLLTLLGILTQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQI-DSEIDGYSQFLFPAFFMLYNCFYWLYYLILV 448
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000077704.1 (SMESG000077704.1) HSP 1 Score: 481.1 bits (1237), Expect = 7.390e-167 Identity = 253/441 (57.37%), Postives = 324/441 (73.47%), Query Frame = 3
Query: 234 IFLLA-IHVGCN----SCSVAGITRERIMDKILQNYSLNERPIESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDVRLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARXXXXXXXXXXXXXQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVS 1541
IFLLA I C+ S S R I +I Y +RP E QT V V+MK+LAINSV+V+ MEYSTD+YLRQ WVD RL W+NL++FK +N+++VSPSLK LWLPDLFFRNGKEGYVH MT PNYLMRL PNG +LYSQKITMRFSCQMDL+T+PMDTQ CEM+IGSYGYTLD+L+F W + + + +QI EFN+P K T DCT S+T TG YSCLKA F+L+RQLGSY+VSTF+P+ LIV+VSWLNFW+ V++VPAR+ LGL+TLLG+LTQA GIS LPRVSYIKAID+W+I CI+FVI ALLE+AVA++V + ++EV+ IV++EL W A +R + HMQ L+R+ L+FC +L+ LL + A + H K+ + E S +DVYSR+LFP+ F+FYN YW+Y+L++V+
Sbjct: 8 IFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKEDRPKEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARVMLGLVTLLGMLTQAIGISSTLPRVSYIKAIDIWVIWCIIFVICALLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEK--AIDSH--------KKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVLVN 438 The following BLAST results are available for this feature:
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30004877 ID=SMED30004877|Name=Glycine receptor subunit alpha-3|organism=Schmidtea mediterranea sexual|type=transcript|length=1654bpback to top protein sequence of SMED30004877-orf-1 >SMED30004877-orf-1 ID=SMED30004877-orf-1|Name=SMED30004877-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=449bp MTIKQQQSNIFIFLLAIHVGCNSCSVAGITRERIMDKILQNYSLNERPIEback to top Aliases
The feature 'Glycine receptor subunit alpha-3' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
