Neuropeptide receptor

Overview
NameNeuropeptide receptor
Smed IDSMED30004873
Length (bp)1236
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Neuropeptide receptor (SMED30004873) t-SNE clustered cells

Violin plots show distribution of expression levels for Neuropeptide receptor (SMED30004873) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Neuropeptide receptor (SMED30004873) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Neuropeptide receptor (SMED30004873) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30004873

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30004873h1SMcG0020744 SmedASXL_014093SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
X1 cellSMED30004873h1SMcG0020744 SmedASXL_004706SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30004873h1SMcG0020744 SmedASXL_004706SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
non-ciliated neuronSMED30004873h1SMcG0020744 dd_Smed_v4_9381_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30004873h1SMcG0020744 dd_Smed_v6_12338_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30004873h1SMcG0020744 dd_Smed_v4_12338_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Neuropeptide receptor vs. Ensembl Human
Match: NPFFR2 (neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc:HGNC:4525])

HSP 1 Score: 123.25 bits (308), Expect = 1.375e-30
Identity = 96/320 (30.00%), Postives = 163/320 (50.94%), Query Frame = 2
Query:  149 FSDILFPYLQY---------IYGFFYVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKT-------INESD------FCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDE--VIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
            +SDI   Y+ Y         I+   Y  IF L ++GN  VC+I+   +   + T++F+LNL+++DL + +FC+P+T   D I   W FG  MC +   VQ +SV  S  T  AI+VDR+  V +P + +   IK A  ++  IW+ +I+I  P   +   +        +N  +      +C E WP +    +Y+  +    Y  P+ +I++ Y  I I L+    P    +++++  V++  K+K+IKM +IVA+ + LS LP   + + S ++   S N       + I  FAH L+      NPI+Y + N +FR+
Sbjct:   30 YSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLL-DNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK-LTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYA-DLSPNEL-QIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRR 345          
BLAST of Neuropeptide receptor vs. Ensembl Human
Match: NPFFR2 (neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc:HGNC:4525])

HSP 1 Score: 123.25 bits (308), Expect = 1.486e-30
Identity = 96/320 (30.00%), Postives = 163/320 (50.94%), Query Frame = 2
Query:  149 FSDILFPYLQY---------IYGFFYVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKT-------INESD------FCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDE--VIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
            +SDI   Y+ Y         I+   Y  IF L ++GN  VC+I+   +   + T++F+LNL+++DL + +FC+P+T   D I   W FG  MC +   VQ +SV  S  T  AI+VDR+  V +P + +   IK A  ++  IW+ +I+I  P   +   +        +N  +      +C E WP +    +Y+  +    Y  P+ +I++ Y  I I L+    P    +++++  V++  K+K+IKM +IVA+ + LS LP   + + S ++   S N       + I  FAH L+      NPI+Y + N +FR+
Sbjct:   27 YSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLL-DNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK-LTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYA-DLSPNEL-QIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRR 342          
BLAST of Neuropeptide receptor vs. Ensembl Human
Match: NPFFR2 (neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc:HGNC:4525])

HSP 1 Score: 122.479 bits (306), Expect = 7.430e-30
Identity = 97/320 (30.31%), Postives = 165/320 (51.56%), Query Frame = 2
Query:  149 FSDILFPYLQY------IYGFFYVS---IFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGA---XXXXXXXXXXXXXXXXXXXXXTEYK----TINESD------FCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDE--VIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
            +SDI   Y+ Y      +   F +S   IF L ++GN  VC+I+   +   + T++F+LNL+++DL + +FC+P+T   D I   W FG  MC +   VQ +SV  S  T  AI+VDR+  V +P + +   IK A   + ++  + I  +S S  ++ V E K     +N  +      +C E WP +    +Y+  +    Y  P+ +I++ Y  I I L+    P    +++++  V++  K+K+IKM +IVA+ + LS LP   + + S ++   S N       + I  FAH L+      NPI+Y + N +FR+
Sbjct:  129 YSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLL-DNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK-LTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYA-DLSPNEL-QIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRR 444          
BLAST of Neuropeptide receptor vs. Ensembl Human
Match: QRFPR (pyroglutamylated RFamide peptide receptor [Source:HGNC Symbol;Acc:HGNC:15565])

HSP 1 Score: 120.168 bits (300), Expect = 1.645e-29
Identity = 80/294 (27.21%), Postives = 156/294 (53.06%), Query Frame = 2
Query:  200 VSIFILGVVGNLAVCYIIS-CRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLR-------RQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGE-----SIRSRD-EVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTL 1039
            V IF L + GN  V Y+++  +  ++ T+IF+ +L+L+DL +  FC+PVT   + I   W+ G  +C + PFVQ+ +V    +T T I+V+R+  + HP +       R+ F + G V++V+ I    +     L    ++    E   C E+W +  ++ +Y+ F++V+ + LP++V+++ YS I   LW  +  G+     +I  ++   IA  KK+ + M + V   +++   P H++++  ++  S  +  + D T   I     ++  S    NPI+Y ++N +F+K +
Sbjct:   53 VLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQN-ISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEY--SNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNV 343          
BLAST of Neuropeptide receptor vs. Ensembl Human
Match: NPY2R (neuropeptide Y receptor Y2 [Source:HGNC Symbol;Acc:HGNC:7957])

HSP 1 Score: 113.62 bits (283), Expect = 2.274e-27
Identity = 90/317 (28.39%), Postives = 159/317 (50.16%), Query Frame = 2
Query:  173 LQYIYGFFYVSIFILGVVGN-LAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPL-----RRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTIN-----ESDFCSEKWPTENNEM---LYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFA------HLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNK 1063
            +Q +    Y SI +LGV+GN L +  +I  +  ++ T+ F+ NL++ADL +   C+P T  +  +   W  G  +CH+ P+ Q L+V +S++T T I++DR+  + + L     +R +F I G        W  S  ++ PL    EY  I      E   C+EKWP E   +   +YSL  +++ Y LP+ +I  +Y+ I  +L  + +PG +    ++     ++K  KM + V + +++S LP H   L              DS  + +  +       H+++M + F NP+LY W+NS++RK   +   C +
Sbjct:   49 VQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTL-TYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIG------LAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAA----NDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDI----------DSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQ 344          
BLAST of Neuropeptide receptor vs. Ensembl Celegans
Match: npr-6 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q20275])

HSP 1 Score: 122.094 bits (305), Expect = 1.095e-30
Identity = 89/311 (28.62%), Postives = 163/311 (52.41%), Query Frame = 2
Query:  173 LQYIYGFF---YVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKM---ALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKT------INES-DF--CSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTC 1057
            ++Y   FF   Y ++F++   GN  V Y++    R Q+ T+IF+ NL+++D+ +   +L+  P T+ S      WIFG  +CH  P  Q  S+F+S+ T TAI++DRY V+ H     N  I   + + SC+    +     L+ VT Y        I+E  DF  CSE W       ++ + VM+LQ+ LP ++I ++Y    I++W +    +S+  R   I   KK++++M I++ + +++   P +++       +      ++    +++    HL+SM+A  +NPILY ++N +FR+    ++ C
Sbjct:   33 MEYFRPFFISMYCAVFLVASSGNFLVVYVVMTNKRMQTITNIFITNLAVSDIMVNFTSLWLTP-TYTS---IGHWIFGGGLCHGLPLFQGTSIFISTWTLTAIAIDRYIVIVH--NSSNININDRMSMRSCLSFIVLIWLCSLLLVTPYAINMKLNYIHEPCDFLICSEDWSNAEFRSIFGIVVMILQFILPFVLIAISY----IKIWLFLNSRQSMTERKSDIK-RKKRLLRMLIVMVVIFAICWFPFNLLNCLRDLKLDNFMRGYFSFVFLSV----HLMSMTATAWNPILYAFMNETFREEFAKVVPC 328          
BLAST of Neuropeptide receptor vs. Ensembl Celegans
Match: npr-22 (Neuropeptide receptor 22 [Source:UniProtKB/Swiss-Prot;Acc:Q59E83])

HSP 1 Score: 120.939 bits (302), Expect = 3.708e-30
Identity = 107/352 (30.40%), Postives = 174/352 (49.43%), Query Frame = 2
Query:  161 LFPYLQYIYGFFYVSIFILGVVGNLAVCYIIS--CRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIF--MRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF---CSEKW-----PTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIA---TSKKKMIKMFIIVAIFYSLSQLPRHI-IYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPP-TSPKCISAFPDGYSSKKRMLSISSNNAL 1165
            L P ++ +   FY  + +  V GN+ V  +I    RLR +AT+I +LNL++ADL +++FC+P +++   I+   RW+FG  MC +  F+QA++VFLS+ T   IS DR+  +   L   N  I     +      +  SI   L  +   +   + D    C E W       E    +YS  V++LQY +P  V+I+TY+ I I++W  + PG    +  ++I     S KK++ M I+++  ++L  LP  I I +  +F    +   +     + +  FAH L+MS    NPI+Y   N+ FR+       C  SS L P  S K +    D  S + R+  I    +L
Sbjct:   45 LTPSMKMLCILFYSILCVCCVYGNVLVILVIVYFKRLR-TATNILILNLAVADLLISVFCIPFSYWQVLIYDDQRWLFGSMMCSLLAFLQAMAVFLSAWTLVVISFDRWMAIMF-LLTPNIRITRRRALYLVAATWIFSILMALPLLFTTRFFEDQDGLPNCGENWTYFGDSGEQVRKVYSSMVLILQYVVPQAVLIITYTHIGIKMWNSRVPGMQNGATKKMIVDRHESVKKLVPMVILISALFALCWLPLLILINVIPEFYPDINSWGY----ILYLWWFAHGLAMSHSMVNPIIYFIRNARFREGF-----CFFSSKLLPCISFKELRLLTDNTSRRHRLRDIHEVESL 385          
BLAST of Neuropeptide receptor vs. Ensembl Celegans
Match: npr-22 (Neuropeptide receptor 22 [Source:UniProtKB/Swiss-Prot;Acc:Q59E83])

HSP 1 Score: 116.701 bits (291), Expect = 1.184e-28
Identity = 103/330 (31.21%), Postives = 166/330 (50.30%), Query Frame = 2
Query:  161 LFPYLQYIYGFFYVSIFILGVVGNLAVCYIIS--CRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIF--MRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF---CSEKW-----PTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIA---TSKKKMIKMFIIVAIFYSLSQLPRHI-IYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSPKCIS 1102
            L P ++ +   FY  + +  V GN+ V  +I    RLR +AT+I +LNL++ADL +++FC+P +++   I+   RW+FG  MC +  F+QA++VFLS+ T   IS DR+  +   L   N  I     +      +  SI   L  +   +   + D    C E W       E    +YS  V++LQY +P  V+I+TY+ I I++W  + PG    +  ++I     S KK++ M I+++  ++L  LP  I I +  +F    +   +     + +  FAH L+MS    NPI+Y   N+ FR+       C  SS L P    CIS
Sbjct:   45 LTPSMKMLCILFYSILCVCCVYGNVLVILVIVYFKRLR-TATNILILNLAVADLLISVFCIPFSYWQVLIYDDQRWLFGSMMCSLLAFLQAMAVFLSAWTLVVISFDRWMAIMF-LLTPNIRITRRRALYLVAATWIFSILMALPLLFTTRFFEDQDGLPNCGENWTYFGDSGEQVRKVYSSMVLILQYVVPQAVLIITYTHIGIKMWNSRVPGMQNGATKKMIVDRHESVKKLVPMVILISALFALCWLPLLILINVIPEFYPDINSWGY----ILYLWWFAHGLAMSHSMVNPIIYFIRNARFREGF-----CFFSSKLLP----CIS 359          
BLAST of Neuropeptide receptor vs. Ensembl Celegans
Match: npr-2 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:A0A061AKJ8])

HSP 1 Score: 106.686 bits (265), Expect = 2.164e-25
Identity = 85/345 (24.64%), Postives = 159/345 (46.09%), Query Frame = 2
Query:  167 PYLQYIYGFFYVSIFILGVVGNLAVCYI-ISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINE--SDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRL-WFYQTPGESIRSRDEVIATS--------------------------------KKKMIKMFIIVAIFYSLSQLPRHIIYLTSK-----FSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLP 1078
            P +   +   Y+ IF+LG++GN AV Y+ +  R  Q+  +IF+LNL  +++ M L  +P+TF ++ ++ +W F   +C + P VQ  S+F+S+ + +AI++DRY +V  P  +Q    + A+ +   IW+ S+ +  P  +  + + +N    ++CSE WP       Y+  V++ Q+  P   +   Y  I  RL    +T  + +  R +++  S                                +++   +   + + ++ + LP +++ L  +     F    +     D T +  +  AHL+SM     NP LY WLN  F++ L   L     S  P
Sbjct:   23 PTVLVTFSLLYLHIFLLGILGNSAVLYLTMKHRQLQTVQNIFILNLCASNVLMCLTSLPITFITN-VYKQWFFSSPVCKLIPLVQGASIFVSTFSLSAIALDRYNLVVRP-HKQKLSSRSAMMIALLIWVISVVVCMPYGWYMDVEKLNGLCGEYCSEHWPLAEVRKGYTFLVLITQFLFPFATMAFCYYNIFSRLRQRVETKLKKLSERSQLLENSTTCGTTNHIVSINAEAVQNGLENKQRLAVLAQQRRTTTILSCMVLLFAFTWLPHNVVTLMIEYDGFFFHSDETSATSTDHTYIVSMT-AHLISMLTNVTNPFLYAWLNPMFKEMLIKTLRGGSKSPKP 364          
BLAST of Neuropeptide receptor vs. Ensembl Celegans
Match: npr-2 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:A0A061AKJ8])

HSP 1 Score: 106.686 bits (265), Expect = 3.220e-25
Identity = 85/345 (24.64%), Postives = 159/345 (46.09%), Query Frame = 2
Query:  167 PYLQYIYGFFYVSIFILGVVGNLAVCYI-ISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINE--SDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRL-WFYQTPGESIRSRDEVIATS--------------------------------KKKMIKMFIIVAIFYSLSQLPRHIIYLTSK-----FSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLP 1078
            P +   +   Y+ IF+LG++GN AV Y+ +  R  Q+  +IF+LNL  +++ M L  +P+TF ++ ++ +W F   +C + P VQ  S+F+S+ + +AI++DRY +V  P  +Q    + A+ +   IW+ S+ +  P  +  + + +N    ++CSE WP       Y+  V++ Q+  P   +   Y  I  RL    +T  + +  R +++  S                                +++   +   + + ++ + LP +++ L  +     F    +     D T +  +  AHL+SM     NP LY WLN  F++ L   L     S  P
Sbjct:   48 PTVLVTFSLLYLHIFLLGILGNSAVLYLTMKHRQLQTVQNIFILNLCASNVLMCLTSLPITFITN-VYKQWFFSSPVCKLIPLVQGASIFVSTFSLSAIALDRYNLVVRP-HKQKLSSRSAMMIALLIWVISVVVCMPYGWYMDVEKLNGLCGEYCSEHWPLAEVRKGYTFLVLITQFLFPFATMAFCYYNIFSRLRQRVETKLKKLSERSQLLENSTTCGTTNHIVSINAEAVQNGLENKQRLAVLAQQRRTTTILSCMVLLFAFTWLPHNVVTLMIEYDGFFFHSDETSATSTDHTYIVSMT-AHLISMLTNVTNPFLYAWLNPMFKEMLIKTLRGGSKSPKP 389          
BLAST of Neuropeptide receptor vs. Ensembl Fly
Match: RYa-R (gene:FBgn0004842 transcript:FBtr0085100)

HSP 1 Score: 177.563 bits (449), Expect = 1.375e-50
Identity = 106/301 (35.22%), Postives = 165/301 (54.82%), Query Frame = 2
Query:  170 YLQYIYGFFYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPL------RRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNML 1051
            Y + I    Y+ IFI  ++GN  VCYI+    R ++ T+ F+ +L++ D+ M+ FCVP +F S  I   W FG A+CH   + QA+SV +S+ T  AIS+DRY  +  PL      R   F I G  F+     +    +S   I ++ + T  E   C E WP+   E  Y+L +  LQ+ +P+ V+I TY+ I IR+W  + PGE+  +RD+ +A SK+KM+KM + V I ++   LP +I+ L     ++  +   WD        F H L+MS C YNPI+Y ++N+ FR     ++
Sbjct:  103 YFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNILQLL----LNDEEFAHWDPLPYVWFAF-HWLAMSHCCYNPIIYCYMNARFRSGFVQLM 398          
BLAST of Neuropeptide receptor vs. Ensembl Fly
Match: RYa-R (gene:FBgn0004842 transcript:FBtr0345268)

HSP 1 Score: 177.178 bits (448), Expect = 1.875e-50
Identity = 106/301 (35.22%), Postives = 165/301 (54.82%), Query Frame = 2
Query:  170 YLQYIYGFFYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPL------RRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNML 1051
            Y + I    Y+ IFI  ++GN  VCYI+    R ++ T+ F+ +L++ D+ M+ FCVP +F S  I   W FG A+CH   + QA+SV +S+ T  AIS+DRY  +  PL      R   F I G  F+     +    +S   I ++ + T  E   C E WP+   E  Y+L +  LQ+ +P+ V+I TY+ I IR+W  + PGE+  +RD+ +A SK+KM+KM + V I ++   LP +I+ L     ++  +   WD        F H L+MS C YNPI+Y ++N+ FR     ++
Sbjct:  103 YFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNILQLL----LNDEEFAHWDPLPYVWFAF-HWLAMSHCCYNPIIYCYMNARFRSGFVQLM 398          
BLAST of Neuropeptide receptor vs. Ensembl Fly
Match: RYa-R (gene:FBgn0004842 transcript:FBtr0345267)

HSP 1 Score: 176.407 bits (446), Expect = 9.380e-50
Identity = 106/301 (35.22%), Postives = 165/301 (54.82%), Query Frame = 2
Query:  170 YLQYIYGFFYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPL------RRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNML 1051
            Y + I    Y+ IFI  ++GN  VCYI+    R ++ T+ F+ +L++ D+ M+ FCVP +F S  I   W FG A+CH   + QA+SV +S+ T  AIS+DRY  +  PL      R   F I G  F+     +    +S   I ++ + T  E   C E WP+   E  Y+L +  LQ+ +P+ V+I TY+ I IR+W  + PGE+  +RD+ +A SK+KM+KM + V I ++   LP +I+ L     ++  +   WD        F H L+MS C YNPI+Y ++N+ FR     ++
Sbjct:  103 YFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNILQLL----LNDEEFAHWDPLPYVWFAF-HWLAMSHCCYNPIIYCYMNARFRSGFVQLM 398          
BLAST of Neuropeptide receptor vs. Ensembl Fly
Match: Lkr (gene:FBgn0035610 transcript:FBtr0077149)

HSP 1 Score: 122.479 bits (306), Expect = 4.026e-30
Identity = 91/296 (30.74%), Postives = 146/296 (49.32%), Query Frame = 2
Query:  194 FYVSIFILGVVGNLAVCYIISC-RLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQ------NFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINES-----DFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPR---HIIYLTSKFSVSTSQNPFWDSTTVTILNF-AHLLSMSACFYNPILYVWLNSSFRK 1033
            FY  I I+ V+GN  V ++++  R  ++ T++++ NL+ AD+ + LFC+P  F    +   W     MC   PFVQALSV +S  T TAI++DR+  + +PLR +       F I G   +     +              ++  NE+      FC  K  +++    +   ++ +QY +P  VI   Y  +A+RLW  + PG +  SRD  +  +KKK+IKM IIV I + L  LP    +I+Y+T             D   ++I+ F    L+MS   YNP +Y   N  F++
Sbjct:   41 FYGGISIVAVIGNTLVIWVVATTRQMRTVTNMYIANLAFADVIIGLFCIPFQF-QAALLQSWNLPWFMCSFCPFVQALSVNVSVFTLTAIAIDRHRAIINPLRARPTKFVSKFIIGGIWMLALLFAVPFAIAFRVEELTERFRENNETYNVTRPFCMNKNLSDDQLQSFRYTLVFVQYLVPFCVISFVYIQMAVRLWGTRAPGNAQDSRDITLLKNKKKVIKMLIIVVIIFGLCWLPLQLYNILYVTIP--------EINDYHFISIVWFCCDWLAMSNSCYNPFIYGIYNEKFKR 327          
BLAST of Neuropeptide receptor vs. Ensembl Fly
Match: TkR99D (gene:FBgn0004622 transcript:FBtr0301656)

HSP 1 Score: 121.324 bits (303), Expect = 7.933e-30
Identity = 88/302 (29.14%), Postives = 151/302 (50.00%), Query Frame = 2
Query:  170 YLQYIYGFFYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFF----SDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPL-----RRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPT-----ENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFR 1030
            + Q ++   +  + I+   GNL V +I+    R ++ T+ F++NLS+AD  ++   V   ++    SD     W FG   C +  F+  LS+  S  T  AIS+DRY  +  PL     +R N  I  AV  ++   I    +          + ++    C  +WP         E LY++ +++L YFLPI+ + +TYS + I LW  +T GE    + E +  SK++++KM I+V + +++  LP H  ++ +    + ++ PF     + I    + L+MS   YNPI+Y W+NS FR
Sbjct:   99 WRQVLWSILFGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSD-----WPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAI-AAVIWLASTLISCPMMIIYRTEEVPVRGLSNRTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKTIGECTPRQVENVR-SKRRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPFIQELYLAI----YWLAMSNSMYNPIIYCWMNSRFR 389          
BLAST of Neuropeptide receptor vs. Ensembl Zebrafish
Match: npy7r (neuropeptide Y receptor Y7 [Source:ZFIN;Acc:ZDB-GENE-040924-9])

HSP 1 Score: 121.324 bits (303), Expect = 1.967e-30
Identity = 97/315 (30.79%), Postives = 157/315 (49.84%), Query Frame = 2
Query:  197 YVSIFILGVVGNLAVCY-IISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYF-VVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF----CSEKWP--TENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSPKCISAFPDG 1117
            Y  I +LG+VGN  V Y II  R  ++ T+ F+ NL+LADL +   C+P T     +   W FG  MCH+ P+ QALSV +S +T T I+++RY  +VFH  +R N      +  ++  +   ++    +     Y+ I   D     CSEKWP  T  + ++YSL +++LQY +P+ +I   Y  I I+L  + +P     +R++ I   +KK  KM  +V + +++  LP H+  L S   +      +       I    H+++M + F NP+LY W+N ++R        C              S +PDG
Sbjct:   54 YSLIILLGLVGNTLVIYMIILYRNMRTVTNYFIANLALADLMVDTVCLPFTLVY-TLLDEWKFGAVMCHMVPYSQALSVHVSILTLTIIALERYRCIVFHLGQRLNRCTSFIIIGLTWAFAAILAGPLAIFREYRYEEIPYIDLRIAVCSEKWPNGTNRDAVIYSLSMLLLQYVVPLAIISYAYVCIWIKLKNHVSPS----NRNDGI-VRRKKTTKMLALVVVVFAVCWLPFHMFQLASDLDLILKFKEY-----KLIYTLFHIVAMCSTFVNPLLYGWMNQNYRNGFLMFFRCEHKPD---------SIYPDG 348          
BLAST of Neuropeptide receptor vs. Ensembl Zebrafish
Match: prlhr2a (prolactin releasing hormone receptor 2a [Source:ZFIN;Acc:ZDB-GENE-060209-1])

HSP 1 Score: 120.553 bits (301), Expect = 3.270e-30
Identity = 86/308 (27.92%), Postives = 152/308 (49.35%), Query Frame = 2
Query:  197 YVSIFILGVVGNLAVCYIISCRLRQ--SATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF--CSEKWPTENNEML-YSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSPKCISA 1105
            Y  + ++GV GN  + Y+I C+ ++  + T+ F+ NL+ +D+ M   CVP T         W+FGR MC++   +Q ++V++S  T TAI VDRY+   HPL+++   +    +++S IWI S  +  P +  T +    +  F  C E W  +  E L Y+   + + Y LP+  + ++Y  I+++L     PG   +S+ E     K+K  ++  +V   + +  LP  +  +     +      ++    + I    HL  MS+   NP LY WL+  FR  L  M TC++   +   +  C +A
Sbjct:   65 YALVVLVGVFGNYLLLYVI-CQTKKMHNVTNFFIGNLAFSDMLMCATCVPFTLAYAFNPRGWVFGRFMCYLVFLIQPVTVYVSVFTLTAIGVDRYYATVHPLKKR-ISVLACTYLLSGIWILSCGLVAPAVAHTYHVEFKDEGFTICEEFWMGQEKERLAYAYSTLFITYVLPLSALCISYLCISVKLRNCVVPGHRTQSQAEAQRARKRKTFRLVSLVVAAFGICWLPISVFNVLRDIDIDLIDKRYF----LLIQLLCHLCGMSSSCCNPFLYAWLHDRFRAELRKMFTCHRRIGIGIPANNCATA 366          
BLAST of Neuropeptide receptor vs. Ensembl Zebrafish
Match: CU915819.2 (neuropeptide FF receptor 2a [Source:NCBI gene;Acc:560955])

HSP 1 Score: 118.627 bits (296), Expect = 3.300e-29
Identity = 97/323 (30.03%), Postives = 166/323 (51.39%), Query Frame = 2
Query:  131 SNFSLPFSDILF-------PYLQYIYGFFYVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXX---XXXXXXTEYKTI------NESD---FCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKK--MIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
            S F LP ++I +       P +  ++   Y+ IF++ ++GN  VC+I+   +  ++ T++F+LNL+++DL + +FC+P T   D I   W FG  +C +   VQ +SV  S  T  AI+VDR+  + +P  +Q   I  A F++  IW+ ++SI      ++ VT+ + I      N S    +C E WP +    +Y+  +    Y  P+ +I++ Y+ I I L+    P       D   + SKKK  +IKM +IVA+ + LS LP   + + + +   T     +    + I  FAH L+      NPI+Y + N +FR+
Sbjct:   24 SEFFLPLNNITYVGYYLHQPSVAAVFIVSYLLIFLVCMIGNGVVCFIVLRSKNMRTVTNLFILNLAISDLLVGIFCMPTTLL-DNIITGWPFGSMVCKMSGMVQGISVSASVFTLVAIAVDRFRCIVYPF-KQKLTISTATFIIVIIWVLAVSIMCPSGVMLQVTKEQNIRVFRGNNRSSPFYWCRENWPNQEMRKIYTTVLFANIYLAPLSLIVIMYARIGITLFKTAMPAGGKHGHDNRHSVSKKKQRVIKMLLIVALLFILSWLPLWTLMMLTDYVKLTEHQ--YRVINIYIYPFAHWLAFFNSSVNPIIYGFFNENFRR 342          
BLAST of Neuropeptide receptor vs. Ensembl Zebrafish
Match: AL929374.1 (neuropeptide FF receptor 2a [Source:NCBI gene;Acc:560955])

HSP 1 Score: 118.627 bits (296), Expect = 3.300e-29
Identity = 97/323 (30.03%), Postives = 166/323 (51.39%), Query Frame = 2
Query:  131 SNFSLPFSDILF-------PYLQYIYGFFYVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXX---XXXXXXTEYKTI------NESD---FCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKK--MIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
            S F LP ++I +       P +  ++   Y+ IF++ ++GN  VC+I+   +  ++ T++F+LNL+++DL + +FC+P T   D I   W FG  +C +   VQ +SV  S  T  AI+VDR+  + +P  +Q   I  A F++  IW+ ++SI      ++ VT+ + I      N S    +C E WP +    +Y+  +    Y  P+ +I++ Y+ I I L+    P       D   + SKKK  +IKM +IVA+ + LS LP   + + + +   T     +    + I  FAH L+      NPI+Y + N +FR+
Sbjct:   24 SEFFLPLNNITYVGYYLHQPSVAAVFIVSYLLIFLVCMIGNGVVCFIVLRSKNMRTVTNLFILNLAISDLLVGIFCMPTTLL-DNIITGWPFGSMVCKMSGMVQGISVSASVFTLVAIAVDRFRCIVYPF-KQKLTISTATFIIVIIWVLAVSIMCPSGVMLQVTKEQNIRVFRGNNRSSPFYWCRENWPNQEMRKIYTTVLFANIYLAPLSLIVIMYARIGITLFKTAMPAGGKHGHDNRHSVSKKKQRVIKMLLIVALLFILSWLPLWTLMMLTDYVKLTEHQ--YRVINIYIYPFAHWLAFFNSSVNPIIYGFFNENFRR 342          
BLAST of Neuropeptide receptor vs. Ensembl Zebrafish
Match: NPFFR2 (neuropeptide FF receptor 2a [Source:NCBI gene;Acc:560955])

HSP 1 Score: 118.627 bits (296), Expect = 3.300e-29
Identity = 97/323 (30.03%), Postives = 166/323 (51.39%), Query Frame = 2
Query:  131 SNFSLPFSDILF-------PYLQYIYGFFYVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXX---XXXXXXTEYKTI------NESD---FCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKK--MIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
            S F LP ++I +       P +  ++   Y+ IF++ ++GN  VC+I+   +  ++ T++F+LNL+++DL + +FC+P T   D I   W FG  +C +   VQ +SV  S  T  AI+VDR+  + +P  +Q   I  A F++  IW+ ++SI      ++ VT+ + I      N S    +C E WP +    +Y+  +    Y  P+ +I++ Y+ I I L+    P       D   + SKKK  +IKM +IVA+ + LS LP   + + + +   T     +    + I  FAH L+      NPI+Y + N +FR+
Sbjct:   24 SEFFLPLNNITYVGYYLHQPSVAAVFIVSYLLIFLVCMIGNGVVCFIVLRSKNMRTVTNLFILNLAISDLLVGIFCMPTTLL-DNIITGWPFGSMVCKMSGMVQGISVSASVFTLVAIAVDRFRCIVYPF-KQKLTISTATFIIVIIWVLAVSIMCPSGVMLQVTKEQNIRVFRGNNRSSPFYWCRENWPNQEMRKIYTTVLFANIYLAPLSLIVIMYARIGITLFKTAMPAGGKHGHDNRHSVSKKKQRVIKMLLIVALLFILSWLPLWTLMMLTDYVKLTEHQ--YRVINIYIYPFAHWLAFFNSSVNPIIYGFFNENFRR 342          
BLAST of Neuropeptide receptor vs. Ensembl Xenopus
Match: GPR83 (G protein-coupled receptor 83 [Source:NCBI gene;Acc:100486806])

HSP 1 Score: 136.732 bits (343), Expect = 1.586e-35
Identity = 101/342 (29.53%), Postives = 174/342 (50.88%), Query Frame = 2
Query:  167 PYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKG----AXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLY---SLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHI-IYLTSKFSVSTSQNPFWDSTTVTILNFA-HLLSMSACFYNPILYVWLNSSFRKTLTNMLT-CNKSSS-----LPPTSPKCISAFPDGYSSKKRMLS 1144
            P ++ +    Y  I +  + GN+ VC+++    R  SATS+F++NL++AD+ + L   P T  +  +   W+FG+ MCHV  F Q  S+ +S++T TAI+VDR+ V+ HPL+ +   +KG    A+  +           +  +F  EY   N    C   +P E +++ +    L   +L Y LP+++I + Y+ +A +LW     G+    +   +   KKK IKM ++V + +++   P +  + L S  ++ T+            L FA H  +MS+  YNP +Y WLN +FR  L  +L  C K +      LP + P    A+P+  S K+ ++S
Sbjct:   68 PMVKALLIVAYSFIIVFSLFGNVLVCHVVIKNKRMHSATSLFIVNLAVADILITLLNTPFTL-ARFVNSTWMFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISTVKGVAYIAIIWIMATCFSLPHAIYQKLFTFEYSEENIRSLCLPDFP-EPSDLFWKYLDLATFILLYVLPLLIISVAYTTVAKKLWLRNAIGDVTTEQYFALRRKKKKTIKMLMLVVVLFAVCWFPLNCYVVLLSSQTIRTNN----------ALYFAFHWFAMSSTCYNPFIYCWLNDNFRSELKALLNMCKKPTGPSEHMLPSSVPSYRVAWPENRSFKRSLVS 397          
BLAST of Neuropeptide receptor vs. Ensembl Xenopus
Match: ENSXETT00000044281.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:115219157:115249407:-1 gene:ENSXETG00000019365.1 transcript:ENSXETT00000044281.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 124.405 bits (311), Expect = 1.187e-31
Identity = 91/316 (28.80%), Postives = 162/316 (51.27%), Query Frame = 2
Query:  125 NQSNFSLPFSDI-LFPYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLRQ--SATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF--CSEKWPTENNEML-YSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLT 1054
            N SN S PF+ + L    + ++   Y  + ++G+ GN  + Y+I CR R+  + T+ F+ NL+ +D+ M   CVP T         W+FG+ MC+    +Q ++V++S  T TAI+VDRY+   HPL+++   +   ++V+  IW+ S ++  P I  T +    +  F  C E W  +  E L Y+   +++ Y LP+  + ++Y  I ++L     PG   +S+ E     K+K+ ++ ++V   + +  LP H+  +     ++     ++    + I  F H  +MS+   NP LY WL+  FR  L  M T
Sbjct:   16 NGSNASAPFTGVQLIQSYKPLFIPCYTLVVLIGIFGNYLLLYVI-CRTRKMHNVTNFFIGNLAFSDMLMCATCVPFTLAYAFNPQGWVFGKFMCYFVFLMQPVTVYVSVFTLTAIAVDRYYATVHPLKKR-ISVTTCIYVLMGIWLLSCALVGPAIAHTYHVEFQQEGFTICEEFWMGKETERLAYAYSTLIITYILPLSAVSLSYICITVKLKNRVVPGHPTQSQAEFDRLRKRKIFRLIVLVVTAFGICWLPIHVFNIIRDIDINLINKHYF----LHIQLFCHWFAMSSSCCNPFLYAWLHDRFRSELRKMFT 325          
BLAST of Neuropeptide receptor vs. Ensembl Xenopus
Match: gamt (guanidinoacetate N-methyltransferase [Source:Xenbase;Acc:XB-GENE-947462])

HSP 1 Score: 121.324 bits (303), Expect = 6.031e-30
Identity = 91/305 (29.84%), Postives = 152/305 (49.84%), Query Frame = 2
Query:  197 YVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYK-----TINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFA-HLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSP 1090
            Y  I ++ + GN+ VC+++    R QSATS+F++NL++AD+ + L   P T     +   W+FG+ MCHV  FVQ  SV +S +T  AI++DR+ V+ HPL+ +   +KG + ++   ++ S       ++    +     T+      S  +P +       L   VL Y LP+IVI +TY+ +A +LW     G+    +       KK  +KM ++V + +++   P +   +     V +S N  +         FA H  +MS+  YNP +Y WLN SFR  L  +L   +  S   + P
Sbjct:   76 YSVIIVISLFGNILVCHVVIKNSRMQSATSLFIVNLAVADIMITLLNTPFTLVR-FVSSTWVFGKLMCHVSRFVQYCSVHVSVLTLMAIALDRHQVIMHPLKPRMSTVKGIICIIVIWFMASGFSLPHAVYQKLEQFFIGNTVRMVCLPSFPYPADLFWKYLDLATFVLLYVLPLIVISITYTTVAKKLWLRNAIGDITMEQYYAHRRKKKMTLKMLMLVVVVFAVCWFPLNCYLVLMSSKVISSNNAIY---------FAFHWFAMSSTCYNPFIYCWLNESFRSELKALLCVCRRRSPAQSHP 370          
BLAST of Neuropeptide receptor vs. Ensembl Xenopus
Match: taf1b (TATA-box binding protein associated factor, RNA polymerase I, B [Source:Xenbase;Acc:XB-GENE-992275])

HSP 1 Score: 119.398 bits (298), Expect = 1.385e-29
Identity = 87/298 (29.19%), Postives = 154/298 (51.68%), Query Frame = 2
Query:  197 YVSIFILGVVGNLAVCY-IISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYF-VVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF----CSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLT--SKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKS 1066
            Y  I +LG+VGN  V Y I+  +  ++ T+ F+ NL++ADL +  FC+P T     +   W FG  +CH+FP+ QA+SV +S++T   I++DRY+ +VFH   R +  +   +  ++ I    ++I   +     Y+ +   +     C+E W T  +  +YSL +++LQY LP+ VI   Y    +R+WF      S  +R E     +K   KM +++ + +++  LP HI  L    +++V+  +N         +    H+++M + F NP LY W+N ++R        C  +
Sbjct:   46 YSLIILLGLVGNSLVIYMIVKYKNMRTVTNFFIANLAIADLMVDSFCLPFTLVYT-LMDEWKFGSVLCHLFPYAQAMSVNVSTLTLIVIALDRYWCIVFHLNSRISKNLSFLIISITWITAAILAIPLAVFREFRYEDLPPFNLKIAVCAENW-TNRDSTIYSLSMLILQYALPLAVICYAY----LRIWFKLKNHISPTTRSES-QQRRKNTTKMLVMMVVVFAVCWLPFHIFQLAIDLEWTVAIHENKL-------LYTIFHVVAMCSTFVNPFLYGWMNKNYRHGFLTFFGCKDT 329          
BLAST of Neuropeptide receptor vs. Ensembl Xenopus
Match: clstn2 (calsyntenin 2 [Source:Xenbase;Acc:XB-GENE-958942])

HSP 1 Score: 114.005 bits (284), Expect = 2.315e-27
Identity = 91/299 (30.43%), Postives = 154/299 (51.51%), Query Frame = 2
Query:  197 YVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF---------------CSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTP-GESIRSRDEVIATSKKK--MIKMFIIVAIFYSLSQLPRHIIYLTSKFS-VSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
            Y  IF++ ++GN+ VC+I+   R  ++ T++F+LNL+++DL + +FC+P T   D +   W F   MC +   VQ +SV  S  T  AI+V+R+  + +P  RQ   ++ A+  +  IW+ ++ I  P        T+ + DF               C E+WP      +Y+  +    Y  P+ +I++ Y+ IA +L+    P   S+   +E    SK+K  +I M IIVA+F+SLS LP   + L + +  +S  Q    +   V +  FAH L+      NPI+Y + N +FR+
Sbjct:   45 YTFIFLMCMIGNMLVCFIVLKNRQMRTVTNMFILNLAISDLLVGIFCMPTTLV-DNLITGWPFDNIMCKMSGLVQGMSVSASVFTLVAIAVERFRCIVYPF-RQKLTLRKAIITIIIIWVLALIIMCPSAVTL---TVTKDDFHFMVDDYNNYYPLYSCWEEWPDTEMRKIYTTVLFSHIYLAPLTLIVIMYARIAFKLFKSSAPIRGSVSEENEGRRVSKRKVRVIYMLIIVALFFSLSWLPLWTLMLLTDYGHLSDYQ---LNLIAVYVFPFAHWLAFFNSSVNPIIYGYFNENFRR 335          
BLAST of Neuropeptide receptor vs. Ensembl Mouse
Match: Npy2r (neuropeptide Y receptor Y2 [Source:MGI Symbol;Acc:MGI:108418])

HSP 1 Score: 116.316 bits (290), Expect = 1.351e-28
Identity = 93/311 (29.90%), Postives = 157/311 (50.48%), Query Frame = 2
Query:  173 LQYIYGFFYVSIFILGVVGN-LAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPL-----RRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTIN-----ESDFCSEKWPTENNEM---LYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNK 1063
            +Q I    Y SI +LGVVGN L +  +I  +  ++ T+ F+ NL++ADL +   C+P T  +  +   W  G  +CH+ P+ Q L+V +S++T T I++DR+  + + L     +R +F I G        W  S  ++ PL    EY  I      E   C+EKWP E   +   +YSL  +++ Y LP+ +I  +Y+ I  +L  + +PG +     +     + KM KM + V + +++S LP H   L    +V    +         I    H+++M + F NP+LY W+NS++RK   +   C +
Sbjct:   49 VQVILILAYCSIILLGVVGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTL-TYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIG------LAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSVYGTVYSLSTLLILYVLPLGIISFSYTRIWSKLRNHVSPGAASDHYHQ----RRHKMTKMLVCVVVVFAVSWLPLHAFQL----AVDIDSHVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQ 344          
BLAST of Neuropeptide receptor vs. Ensembl Mouse
Match: Npy2r (neuropeptide Y receptor Y2 [Source:MGI Symbol;Acc:MGI:108418])

HSP 1 Score: 116.316 bits (290), Expect = 1.351e-28
Identity = 93/311 (29.90%), Postives = 157/311 (50.48%), Query Frame = 2
Query:  173 LQYIYGFFYVSIFILGVVGN-LAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPL-----RRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTIN-----ESDFCSEKWPTENNEM---LYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNK 1063
            +Q I    Y SI +LGVVGN L +  +I  +  ++ T+ F+ NL++ADL +   C+P T  +  +   W  G  +CH+ P+ Q L+V +S++T T I++DR+  + + L     +R +F I G        W  S  ++ PL    EY  I      E   C+EKWP E   +   +YSL  +++ Y LP+ +I  +Y+ I  +L  + +PG +     +     + KM KM + V + +++S LP H   L    +V    +         I    H+++M + F NP+LY W+NS++RK   +   C +
Sbjct:   49 VQVILILAYCSIILLGVVGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTL-TYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIG------LAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSVYGTVYSLSTLLILYVLPLGIISFSYTRIWSKLRNHVSPGAASDHYHQ----RRHKMTKMLVCVVVVFAVSWLPLHAFQL----AVDIDSHVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQ 344          
BLAST of Neuropeptide receptor vs. Ensembl Mouse
Match: Npy2r (neuropeptide Y receptor Y2 [Source:MGI Symbol;Acc:MGI:108418])

HSP 1 Score: 116.316 bits (290), Expect = 1.351e-28
Identity = 93/311 (29.90%), Postives = 157/311 (50.48%), Query Frame = 2
Query:  173 LQYIYGFFYVSIFILGVVGN-LAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPL-----RRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTIN-----ESDFCSEKWPTENNEM---LYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNK 1063
            +Q I    Y SI +LGVVGN L +  +I  +  ++ T+ F+ NL++ADL +   C+P T  +  +   W  G  +CH+ P+ Q L+V +S++T T I++DR+  + + L     +R +F I G        W  S  ++ PL    EY  I      E   C+EKWP E   +   +YSL  +++ Y LP+ +I  +Y+ I  +L  + +PG +     +     + KM KM + V + +++S LP H   L    +V    +         I    H+++M + F NP+LY W+NS++RK   +   C +
Sbjct:   49 VQVILILAYCSIILLGVVGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTL-TYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIG------LAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSVYGTVYSLSTLLILYVLPLGIISFSYTRIWSKLRNHVSPGAASDHYHQ----RRHKMTKMLVCVVVVFAVSWLPLHAFQL----AVDIDSHVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQ 344          
BLAST of Neuropeptide receptor vs. Ensembl Mouse
Match: Npffr2 (neuropeptide FF receptor 2 [Source:MGI Symbol;Acc:MGI:1860130])

HSP 1 Score: 114.775 bits (286), Expect = 1.037e-27
Identity = 91/339 (26.84%), Postives = 157/339 (46.31%), Query Frame = 2
Query:  149 FSDILFPYLQY---------IYGFFYVSIFILGVVGNLAVCYI-ISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIK----------GAXXXXXXXXXXXXXXXXXXXXXTEYKTINESD---FCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEV---IATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTS 1087
            +SDI   Y+ Y         ++   Y+ IF+L +VGN  VC+I I  R   + T+ F+LNL+++DL + +FC+P+T   D I   W FG +MC +   VQ +SV  S  T  AI+VDR+  V +P + +   +K          G    +       + +     +     + N++    +C E WP      +Y+  +    Y  P+ +I++ Y+ I   L  ++T       +  V   ++  K+K+IKM + VA+ + LS LP   + + S ++   S N       + I  FAH L+      NPI+Y + N +FR    +     +  + P  +
Sbjct:   27 YSDINITYVNYYLHQPQVAAVFISSYLLIFVLCMVGNTVVCFIVIRNRHMHTVTNFFILNLAISDLLVGIFCMPITLL-DNIIAGWPFGSSMCKISGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPK-LTVKTAFVTIVIIWGLAIAIMTPSAIMLHVQEEKYYRVRLSSHNKTSTVYWCREDWPRHEMRRIYTTVLFATIYLAPLSLIVIMYARIGASL--FKTAAHCTGKQRPVQWHVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYT-DLSPNKL-RIINIYIYPFAHWLAFCNSSVNPIIYGFFNENFRNGFQDAFQICQKKAKPQEA 359          
BLAST of Neuropeptide receptor vs. Ensembl Mouse
Match: Tacr2 (tachykinin receptor 2 [Source:MGI Symbol;Acc:MGI:98477])

HSP 1 Score: 113.235 bits (282), Expect = 1.927e-27
Identity = 86/296 (29.05%), Postives = 133/296 (44.93%), Query Frame = 2
Query:  197 YVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFF--SDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTI---NESDFCSEKWPTENNE---MLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTC 1057
            Y+++ ++ V GN  V +II    R ++ T+ F++NL+LADL MA F     F   S  I   W FG   C+        ++F+S  + TAI+ DRY  + HP +    P   A    + I +  +           Y TI     +  C   WP +N     +LY L V VL YFLP++V+   YS I + LW    P       +     +KKK +K  ++V + +++  LP H+ ++   F        F     + +      L+MS+  YNPI+Y  LN  FR        C
Sbjct:   40 YLALVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNI---WYFGSTFCYFQNLFPVTAMFVSIYSMTAIAADRYMAIVHPFQ----PRLSAPSTKAVIAVIWLVALALASPQCFYSTITVDQGATKCVVAWPNDNGGKMLLLYHLVVFVLIYFLPLVVMFAAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVVTFAICWLPYHLYFILGTFQEDIYYRKFIQQVYLALF----WLAMSSTMYNPIIYCCLNHRFRSGFRLAFRC 324          
BLAST of Neuropeptide receptor vs. UniProt/SwissProt
Match: sp|P25931|RYAR_DROME (RYamide receptor OS=Drosophila melanogaster OX=7227 GN=RYa-R PE=2 SV=2)

HSP 1 Score: 177.563 bits (449), Expect = 1.379e-49
Identity = 106/301 (35.22%), Postives = 165/301 (54.82%), Query Frame = 2
Query:  170 YLQYIYGFFYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPL------RRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNML 1051
            Y + I    Y+ IFI  ++GN  VCYI+    R ++ T+ F+ +L++ D+ M+ FCVP +F S  I   W FG A+CH   + QA+SV +S+ T  AIS+DRY  +  PL      R   F I G  F+     +    +S   I ++ + T  E   C E WP+   E  Y+L +  LQ+ +P+ V+I TY+ I IR+W  + PGE+  +RD+ +A SK+KM+KM + V I ++   LP +I+ L     ++  +   WD        F H L+MS C YNPI+Y ++N+ FR     ++
Sbjct:  103 YFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNILQLL----LNDEEFAHWDPLPYVWFAF-HWLAMSHCCYNPIIYCYMNARFRSGFVQLM 398          
BLAST of Neuropeptide receptor vs. UniProt/SwissProt
Match: sp|G4WMX4|RYAR_TRICA (RYamide receptor OS=Tribolium castaneum OX=7070 GN=RYa-R PE=2 SV=1)

HSP 1 Score: 140.969 bits (354), Expect = 8.227e-37
Identity = 97/295 (32.88%), Postives = 158/295 (53.56%), Query Frame = 2
Query:  197 YVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF-------------CSEKWPTENNEM--LYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
            Y  IF++ ++GN  VCYI+ S    ++ T+ F+LNL++ D+ + L CVP T  S  +   W FG  +C V  + QALSVF+S+ T  AIS+D+Y ++  PL+ +   I           ++ I+    L   T    IN+ +              C+E++     E   LY+  +M LQY +P +V++ TY++I + +W ++ PGE+  SRD+ IA +K KMIKM + V   Y++  LP +++ +  K  +S        S  V +    H L+MS   YNPI+Y ++N+ FR 
Sbjct:   37 YAIIFVVALIGNSFVCYIVLSSPPMRTVTNFFILNLAIGDVLITLLCVPFTSVS-LLMQYWPFGGILCPVVNYSQALSVFVSAYTLVAISIDKYMIIMWPLKPR---ISKRFATYIIALVWLIAGITVLPSATFTTLINDENILGTSAYEQCDKYICAEEYSKVGQEYGDLYTKVLMFLQYVIPSLVLLFTYTSIGVVIWCHRIPGEAENSRDQRIAKNKTKMIKMMVTVVCVYTICWLPYNVL-MIFKEHIS-------GSVMVYLYFPLHGLAMSHACYNPIIYCYMNARFRN 319          
BLAST of Neuropeptide receptor vs. UniProt/SwissProt
Match: sp|Q9DDN6|NPY2R_CHICK (Neuropeptide Y receptor type 2 OS=Gallus gallus OX=9031 GN=NPY2R PE=3 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 3.648e-30
Identity = 95/330 (28.79%), Postives = 166/330 (50.30%), Query Frame = 2
Query:  173 LQYIYGFFYVSIFILGVVGN-LAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPL-----RRQNFPIKG---AXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTE---NNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFA------HLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSPKCISAF 1108
            +Q I  F Y SI +LGV+GN L +  II  +  ++ T+ F+ NL++ADL +   C+P T     +   W  G  +CH+ P+ QAL+V +S+VT T I++DR+  + + L     +R +F I G   AV  +    +        +  + ++K +     CSEKWP E   N   +YS+ ++++QY LP+ +I   Y+ I  +L  + +PG    + ++     ++K  KM + V + +++S LP H   L S            DS  + +  +       H+++M + F NP+LY W+N+++R        C +   L    P+  +AF
Sbjct:   53 VQIILIFAYCSIILLGVIGNSLVIHVIIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLVY-TLLGEWKLGPVLCHLVPYAQALAVHVSTVTLTVIALDRHRCIVYHLESKISKRISFLIIGVAWAVSALLASPLAIFREYSLIEIIPDFKIV----VCSEKWPGEGQLNYGTIYSVSMLLIQYVLPLAIISYAYTRIWTKLKNHVSPG----AGNDHYHHRRQKTTKMLVCVVVVFAVSWLPFHAFQLVSDI----------DSQVLDLKEYKLIYTVFHVIAMCSTFANPLLYGWMNNNYRTAFLTAFQCEQ--RLDSIHPEVSAAF 361          
BLAST of Neuropeptide receptor vs. UniProt/SwissProt
Match: sp|Q9Y5X5|NPFF2_HUMAN (Neuropeptide FF receptor 2 OS=Homo sapiens OX=9606 GN=NPFFR2 PE=1 SV=2)

HSP 1 Score: 122.479 bits (306), Expect = 3.568e-29
Identity = 97/320 (30.31%), Postives = 165/320 (51.56%), Query Frame = 2
Query:  149 FSDILFPYLQY------IYGFFYVS---IFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGA---XXXXXXXXXXXXXXXXXXXXXTEYK----TINESD------FCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDE--VIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
            +SDI   Y+ Y      +   F +S   IF L ++GN  VC+I+   +   + T++F+LNL+++DL + +FC+P+T   D I   W FG  MC +   VQ +SV  S  T  AI+VDR+  V +P + +   IK A   + ++  + I  +S S  ++ V E K     +N  +      +C E WP +    +Y+  +    Y  P+ +I++ Y  I I L+    P    +++++  V++  K+K+IKM +IVA+ + LS LP   + + S ++   S N       + I  FAH L+      NPI+Y + N +FR+
Sbjct:  129 YSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLL-DNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK-LTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYA-DLSPNEL-QIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRR 444          
BLAST of Neuropeptide receptor vs. UniProt/SwissProt
Match: sp|P05363|NK2R_BOVIN (Substance-K receptor OS=Bos taurus OX=9913 GN=TACR2 PE=2 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 6.087e-29
Identity = 91/294 (30.95%), Postives = 150/294 (51.02%), Query Frame = 2
Query:  197 YVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFF--SDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLR-RQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNE---MLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTC 1057
            Y+++ ++ V+GN  V +II    R ++ T+ F++NL+LADL MA F     F   S  I   W FGRA C+        ++F+S  + TAI+ DRY  + HP + R + P  G   V++ IW+ +++++FP  F +   T   +  C   WP ++     +LY L V+ L YFLP++V+ + YS I + LW    PG      +     +KKK +K  ++V + +++  LP H+ ++   F      + F     + +      L+MS+  YNPI+Y  LN  FR        C
Sbjct:   40 YLALVLVAVMGNATVIWIILAHQRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNI---WYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAP--GTRAVIAGIWLVALALAFPQCFYSTITTDEGATKCVVAWPEDSGGKMLLLYHLIVIALIYFLPLVVMFVAYSVIGLTLWRRSVPGHQAHGANLRHLQAKKKFVKTMVLVVVTFAICWLPYHLYFILGTFQEDIYCHKFIQQVYLALF----WLAMSSTMYNPIIYCCLNHRFRSGFRLAFRC 324          
BLAST of Neuropeptide receptor vs. TrEMBL
Match: A0A193KUS4 (GCR337 OS=Schmidtea mediterranea OX=79327 GN=gcr337 PE=2 SV=1)

HSP 1 Score: 223.016 bits (567), Expect = 2.524e-66
Identity = 128/305 (41.97%), Postives = 194/305 (63.61%), Query Frame = 2
Query:  128 QSNFSLPFSDILFPYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINES-DFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTV-TILNFAHLLSMSACFYNPILYVWLNSSFRKT 1036
             +++S P  D+   Y + ++   +  +FI+G+ GN  +C+I+   + ++AT+IFL NLSLAD+ M L C PVT  SD +   W FG  +C V PF+Q +SVFLS +TH  IS DR+ VVF P++ +    + +  ++   WI SI +S PL+ V E  TIN++ D C E W  +++ ++Y+  V++ QYFLP+  I  TY AIA++LW  + PG S   R+E +  SKK+M+KM IIVA FYSLSQLPRH+++L     +  S   F+ S  V  +L F+H LS+SA  YN  +Y+WLN +F+++
Sbjct:    2 NNSYSSPVQDVSV-YYKVLFSILFSIVFIVGIGGNYCICWILIKDINRNATNIFLFNLSLADILMCLICSPVTLVSDGLLFYWPFGSLLCKVVPFIQGISVFLSGLTHVVISSDRFVVVFFPMKTR-LSNECSWGLIGLTWIISIILSLPLVIVNEISTINQNRDLCEENWKNKDHGLIYTFVVLICQYFLPVAFITSTYIAIAVKLWIRKPPGVSFPGRNEQVNNSKKRMVKMVIIVASFYSLSQLPRHVLFL-----IGYSNELFFSSKHVKELLLFSHFLSISATTYNIFIYLWLNRNFKES 299          
BLAST of Neuropeptide receptor vs. TrEMBL
Match: R7TR01 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_195613 PE=3 SV=1)

HSP 1 Score: 192.586 bits (488), Expect = 1.856e-54
Identity = 116/306 (37.91%), Postives = 174/306 (56.86%), Query Frame = 2
Query:  170 YLQYIYGFFYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLR-RQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKT--INESD---FCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTIL-NFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNK 1063
            Y Q I    Y +I +L V GNL V YI+    R ++ T+ F++NL+ +D+ MA+ C+P TF ++ +   W FG  MC +  ++QA+ VFLS+ T  AIS+DRY  +  PL+ R        V  V  +   ++ +   ++   E +T   N S     C EKWP   +  +YSL +M+LQYFLP+ V++ TYS+IA+ +W  + PGE+  +RD+ +A SK+KM+KM I V I Y+L  LP H + +     V       W    + +L + AH L+MS C YNPI+Y W+NS FR+     L C K
Sbjct:    4 YAQAIIIVMYSTISVLAVGGNLIVVYIVVAYQRMRTVTNYFIVNLACSDILMAVMCIPFTFIANLLMHYWPFGAIMCPIVSYLQAVVVFLSAFTLVAISLDRYRAIMFPLKPRMTTNQVAMVIAVIWMLSLAVPLPIAIMSRIEEQTDRFNASVVRYICKEKWPQLQHRYIYSLCLMILQYFLPLFVLMFTYSSIAVVIWVKKMPGEAENNRDQRMAASKRKMVKMMITVVIIYALCWLPLHTVTI-----VGDVHESVWHFRHIQVLWSGAHWLAMSNCCYNPIVYCWMNSKFRQGFKYSLRCQK 304          
BLAST of Neuropeptide receptor vs. TrEMBL
Match: A0A210Q9U7 (Neuropeptide Y receptor OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT06257 PE=3 SV=1)

HSP 1 Score: 190.274 bits (482), Expect = 1.631e-52
Identity = 110/329 (33.43%), Postives = 184/329 (55.93%), Query Frame = 2
Query:   98 PTLPAMLPLNQSNFSLPFSDILFP-YLQYIYGFFYVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINES---DFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVST----SQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTC 1057
            P L A +P +  + ++  + +  P YLQ I    Y +I IL V GNL VC+I+   R  ++  + F+++L+++DL MAL C+P TF ++ +   W FG  +C V  F+Q+++VFLSS T  AIS+DRY  + +PLR++    +  + +    +I  I      +F   +K +N S    FC E +    ++ LY   +M+LQYF+P+++++ TY  I+  +W  + PGE++ +RD+ +  SK+K+IKM I V + Y++  LP H++ +      S       N  W +        +H L+MS C YNP +Y W+N+ FR     +L C
Sbjct:   22 PLLNASVPADGRS-TIGHTPLQVPIYLQAIIITMYSAIIILSVGGNLTVCFIVFRARRMRTVMNFFIVSLAMSDLLMALLCIPFTFVANLVLNYWPFGDVLCPVVTFLQSVTVFLSSFTLVAISMDRYIAIIYPLRQKMSKKQAFIVIALIWFIAFIIPIPTAMFSWTHKYVNVSTAPKFCQEMFENPEDKRLYGTMIMLLQYFIPLVILMFTYGRISAVMWIDRAPGEAMTTRDQRMTESKRKIIKMMITVVVIYAICWLPLHVLNIAGDVDPSVYDIKGMNYIWMT--------SHWLAMSNCMYNPFIYCWMNAKFRNGFLKVLNC 341          
BLAST of Neuropeptide receptor vs. TrEMBL
Match: V3ZSY8 (G_PROTEIN_RECEP_F1_2 domain-containing protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_72476 PE=3 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 4.808e-52
Identity = 111/304 (36.51%), Postives = 170/304 (55.92%), Query Frame = 2
Query:  170 YLQYIYGFFYVSIFILGVVGNLAVCY-IISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLR-----RQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNP-FWDSTTVTILNFA-HLLSMSACFYNPILYVWLNSSFRKTLTNMLTC 1057
            YLQ I    Y  I +L V GNL VCY I+  R  ++  + F+++L+++D+ MA+FC+P TF ++ +   W FG  +C +  F+Q  +VFLS  T  AIS+DRY  + +PLR     +Q   I G V+  S I     ++        +Y T  E  FC E W        YS+ +++LQYF+P++V+  TY  I   +   + PGE++ +RD ++A SK+K+ KM IIV I Y++  LP H+I      ++  + NP  +D   + I+  A H L+MS C YNP +Y W+NS FR     +L C
Sbjct:    1 YLQAIIITMYTLIIVLAVGGNLIVCYTILRVRRMRTVINFFIISLAISDILMAIFCIPFTFVANLVLNYWPFGDILCPIVTFLQTAAVFLSCFTLVAISIDRYVAIIYPLRQKLSKKQASVIIGCVWFCSFIIPLPTALYSKAHKYVDYPTAPE--FCEEIWSNGTARYTYSVSILLLQYFIPLLVLAFTYGRITYVMCIKKPPGEAVSTRDRIMAESKRKITKMMIIVVIIYAVCWLPLHVI------TIIGAVNPGIYDGQYMNIVWMASHWLAMSNCMYNPFVYCWMNSKFRHGFLRVLNC 296          
BLAST of Neuropeptide receptor vs. TrEMBL
Match: A0A0R3TQ59 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS9660 PE=4 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 1.434e-51
Identity = 109/292 (37.33%), Postives = 162/292 (55.48%), Query Frame = 2
Query:  197 YVSIFILGVVGNLAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTIL-NFAHLLSMSACFYNPILYVWLNSSFRKTLTNML--TCNK 1063
            Y+ + ++ ++GN  VCY+I   L+ S T+IFL NLSL D+   L  +P++  +D     W FG AMC + PF+Q L+V L++ TH  IS DR+ +VF PL+R+          +      + SI      V  Y    ES  C+E W  E ++  Y+L +MV+QYFLP++++I +YS I  +L   Q  G    SR  +   SK+K++KM I V+  Y++SQLPRH+IYL             W+S    I   F+ LLS SA  YNP +Y W+N ++R   + +L   CNK
Sbjct:   33 YIQLMLIALIGNSLVCYVIHRYLQHSVTNIFLYNLSLTDILTTLAVIPISAVADIWLNHWPFGEAMCKIVPFIQCLTVTLTAFTHVLISCDRFLIVFWPLQRRQLLTPRKAKFILLGLWLTASIQAIPNAVVGYLERGESLRCAESWDQEQSKA-YTLTLMVIQYFLPLVLLIFSYSVIVWKLNSTQVGGVISVSRSGMAVRSKRKVVKMMIAVSTIYAISQLPRHVIYLYGTIVE-------WNSRVFAIAWTFSTLLSSSASCYNPFIYAWMNQTYRMGFSRVLCFCCNK 316          
BLAST of Neuropeptide receptor vs. Ensembl Cavefish
Match: npy2rl (neuropeptide Y receptor type 2-like [Source:NCBI gene;Acc:103047056])

HSP 1 Score: 121.709 bits (304), Expect = 1.122e-30
Identity = 105/370 (28.38%), Postives = 180/370 (48.65%), Query Frame = 2
Query:  101 TLPAMLPLNQSNFSLPFSDILFPYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLR--QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYF-VVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINES-----DFCSEKWP-TENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFA------HLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSPKCISAFPDGYSSKKRMLSISSNNAL 1165
            TLPA  P ++  F    + +L   +Q I    Y +I +LGVVGN  V Y++ CR +  ++ T+ F+ NL++ADL +   C+P T  +  +   W FG+ +C   P+ Q L+V +S+VT   I++DR+  +V+H   R +        +++  W+ S  ++ PL    EY  +  S     + C EKWP +  +  LYS+ +++LQY LP+ VI   Y  I  +L  +  P E            ++K  KM + + + +++S LP H   L              DS+ + + +F       H+++M + F NPILY W+N ++R     +  C +   L    PK   A        K + ++ + +AL
Sbjct:   25 TLPAKAP-SEGGFLGDSTRLLG--VQVILILAYSTIILLGVVGNSVVIYVV-CRFKTLRTVTNFFIANLAVADLLVNTLCLPFTL-AYTLLGEWKFGQVLCFTLPYAQGLAVHVSTVTLNVIALDRHRCIVYHLETRMS--KDTCFLIIAITWVISAVLASPLAIFREYGMVELSPGESIEVCGEKWPGSSTDGTLYSISMLLLQYVLPLAVISFAYIRIWSKLRNHVGPAERN-----DRHRRRRKTTKMLVTMVVVFAVSWLPFHAFQLAIDI----------DSSVLVMRDFRLLYTVFHIVAMCSTFANPILYGWMNRNYRSAFIAVFRCEQ--RLDSVHPKGRDA---AAVRNKTVKALEAQDAL 367          
BLAST of Neuropeptide receptor vs. Ensembl Cavefish
Match: npy2r (neuropeptide Y receptor Y2 [Source:ZFIN;Acc:ZDB-GENE-040924-8])

HSP 1 Score: 121.709 bits (304), Expect = 1.772e-30
Identity = 98/339 (28.91%), Postives = 165/339 (48.67%), Query Frame = 2
Query:   95 CPTLPAMLPLNQSNFSLPFSDILFPYLQYIYGFFYVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINES-----DFCSEKWP-TENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFA------HLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSS 1072
            C +LP M         L  S  L   +Q I    Y SI + GV GN  V Y++   R   + T+ F++NL++ADL +   C+P T     ++  W FG+AMC++ P+ Q L+V +S++T   I++DRY  + H +  +         V++  W+ S  ++ PL    EY T + +       C+EKWP +  +  +YS+ +  LQY LP+ VI   Y+ I  +L  + +PG     R       ++K  KM  +V   +++S LP H   L              DS+ + + ++       H+++M + F NPILY W+N ++R     +  C ++ S
Sbjct:   30 CCSLPIMQDEGALLDGLDDSTKLIG-VQVILILAYSSIILFGVTGNALVIYVVYKFRNLHTVTNFFIVNLAVADLLVNTLCLPFTLMY-TLYGEWKFGQAMCYLLPYAQGLAVNVSTITLNIIALDRYRSIVHHMETK-MSKDVCAVVIAVTWVASAVLASPLAIFREYVTFDLTPEQSIQGCAEKWPGSSTDGTVYSISMFFLQYGLPLSVISFAYARIWTKLRKHISPGGGRSDRHR----RRQKTTKMLAVVVAVFAVSWLPFHAFQLAVDI----------DSSVLEMKDYKLLYTVFHIVAMCSAFANPILYGWMNRNYRGAFAAVCKCGRAES 351          
BLAST of Neuropeptide receptor vs. Ensembl Cavefish
Match: prlhr2b (prolactin-releasing peptide receptor-like [Source:NCBI gene;Acc:103046295])

HSP 1 Score: 120.939 bits (302), Expect = 1.864e-30
Identity = 95/333 (28.53%), Postives = 171/333 (51.35%), Query Frame = 2
Query:  125 NQSNFSLPFSDI-LFPYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLRQ--SATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF--CSEKW-PTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSPKCISA 1105
              +N S PF+D+ L    + +    YV + ++GV GN  + Y+I CR R+  + T++F+ NL+ +D+ M + CVP T         W FGR MC++   VQ ++V++S  T TAI+VDRY+   HPL+++   +   V+++S IW+ S ++  P +  T +      D   C E W   E   ++Y+   +++ Y LP+  + ++Y  I+++L     PG   R++ E     K+K+ ++  +V   + +  LP H+  +     +       +    + I    HL +MS+   NP LY WL+  FR  L  + TC +   +  ++ +C +A
Sbjct:   28 GSTNQSYPFADVELLQAFKPLIVPCYVLVVVVGVFGNYLLIYVI-CRSRKMHNVTNVFIGNLAFSDMLMCVTCVPFTLAYAFNPRGWTFGRFMCYLVFLVQPVTVYVSVFTLTAIAVDRYYATVHPLKKR-ISMVACVYILSGIWLLSCTLVAPAVVHTYHVEFEGEDLTICEEFWLGQETERLVYAYSTLLITYILPLSAVCVSYLCISVKLRNCVAPGHRTRAQAEAQRARKRKIFRLVSLVVAAFGVCWLPIHVFNVLRDIDIRLINKRHF----LLIQLLCHLCAMSSSCCNPFLYAWLHDRFRAELRKIFTCRRRIGI--STNRCATA 352          
BLAST of Neuropeptide receptor vs. Ensembl Cavefish
Match: prlhr2b (prolactin-releasing peptide receptor-like [Source:NCBI gene;Acc:103046295])

HSP 1 Score: 120.939 bits (302), Expect = 2.104e-30
Identity = 95/333 (28.53%), Postives = 171/333 (51.35%), Query Frame = 2
Query:  125 NQSNFSLPFSDI-LFPYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLRQ--SATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF--CSEKW-PTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSPKCISA 1105
              +N S PF+D+ L    + +    YV + ++GV GN  + Y+I CR R+  + T++F+ NL+ +D+ M + CVP T         W FGR MC++   VQ ++V++S  T TAI+VDRY+   HPL+++   +   V+++S IW+ S ++  P +  T +      D   C E W   E   ++Y+   +++ Y LP+  + ++Y  I+++L     PG   R++ E     K+K+ ++  +V   + +  LP H+  +     +       +    + I    HL +MS+   NP LY WL+  FR  L  + TC +   +  ++ +C +A
Sbjct:   46 GSTNQSYPFADVELLQAFKPLIVPCYVLVVVVGVFGNYLLIYVI-CRSRKMHNVTNVFIGNLAFSDMLMCVTCVPFTLAYAFNPRGWTFGRFMCYLVFLVQPVTVYVSVFTLTAIAVDRYYATVHPLKKR-ISMVACVYILSGIWLLSCTLVAPAVVHTYHVEFEGEDLTICEEFWLGQETERLVYAYSTLLITYILPLSAVCVSYLCISVKLRNCVAPGHRTRAQAEAQRARKRKIFRLVSLVVAAFGVCWLPIHVFNVLRDIDIRLINKRHF----LLIQLLCHLCAMSSSCCNPFLYAWLHDRFRAELRKIFTCRRRIGI--STNRCATA 370          
BLAST of Neuropeptide receptor vs. Ensembl Cavefish
Match: QRFPR (pyroglutamylated RFamide peptide receptor-like [Source:NCBI gene;Acc:103023541])

HSP 1 Score: 122.094 bits (305), Expect = 2.947e-30
Identity = 82/300 (27.33%), Postives = 152/300 (50.67%), Query Frame = 2
Query:  197 YVSIFILGVVGN-LAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLR--RQNFPIKGAXXXX---XXXXXXXXXXXXXXXXXTEYKTINESDF--CSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGE----SIRSRDEV--IATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLT 1054
            Y +IF L ++GN + +C +      + A+S+F+ +L+L+DL +  FCVP T   + I  +W  G  +C   PFVQ  ++    +T T I+V+RY  + HPL+  RQ  P +    +        +    + F      +Y  + E     C E W +E +  +Y+ F+MV  + LP+  ++  Y+ I+I LW  +  G+    S  +  E+  I+  KK+ +KM I + + +++   P H +++   F  +  ++ + D T   I+     +  S  F NPI+Y ++N +F+K+  + L+
Sbjct:  117 YAAIFALALLGNGVVLCVLAREGAARRASSLFMCSLALSDLLITFFCVPFTLLQN-ISSQWSGGVLVCKTVPFVQTTAIVTGILTMTCIAVERYQGIVHPLKMKRQYTPKRAYKMLGLVWVVSIMVGSPMLFVQQLEVKYDFLYEHHHVCCQELWGSELHRKIYTTFIMVALFLLPLAAMLFLYTRISIELWIRKRVGDVSVLSTMNHREISKISRKKKRAVKMMITIVLMFTICWAPFHTVHML--FEYNDLESKYDDVTLNMIIAVVQAIGFSNSFNNPIVYAFMNENFKKSCVSTLS 413          
BLAST of Neuropeptide receptor vs. Ensembl Sea Lamprey
Match: prlh2r (prolactin releasing hormone 2 receptor [Source:ZFIN;Acc:ZDB-GENE-120411-41])

HSP 1 Score: 134.035 bits (336), Expect = 3.417e-36
Identity = 94/317 (29.65%), Postives = 165/317 (52.05%), Query Frame = 2
Query:  131 SNFSLPFSDI-LFPYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLRQ--SATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF--CSEKW-PTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNK 1063
            +N S PF  + L   L+     FY ++ ++GV+GN  + Y+I CR+++  + T++ + NL+ +DL M   CVP+T         W+FG  MC+    +Q +SV++S  T T I+VDRY V  +PLRR+   I    ++++ IW+ + +++ P +  T Y    E     C E W  TE   + Y+   +VL Y LP++VI ++Y  I+++L     PG   +++ E+    ++K  ++ ++V   +S+  LP HI        +      +++   +      H  +MS+  YNP +Y WL+  FR  L  M T  +
Sbjct:    5 TNASTPFKGVQLIRTLKPFVVLFYTAVVVVGVLGNFLLVYVI-CRVKKMHNVTNLLIGNLAFSDLLMCAMCVPLTLAYVFDARGWVFGSFMCYFVFLMQPVSVYVSVFTLTVIAVDRYIVTVYPLRRR-ITIPTCGYLLAAIWVTACALAAPALAHTYYCEFPEQRMTICEEFWIGTERERLAYAYSTLVLTYGLPLLVISLSYFKISVKLKNRVVPGTVTQNQAEMDRARRRKTFRLLVLVVTAFSVCWLPLHIFNFLRDVDIRLIDKYYFNLVQL----LCHWFAMSSACYNPFIYAWLHDRFRSELKKMFTVKR 315          
BLAST of Neuropeptide receptor vs. Ensembl Sea Lamprey
Match: qrfpr4 (pyroglutamylated RFamide peptide receptor 4 [Source:ZFIN;Acc:ZDB-GENE-091204-354])

HSP 1 Score: 114.39 bits (285), Expect = 6.592e-29
Identity = 79/298 (26.51%), Postives = 151/298 (50.67%), Query Frame = 2
Query:  206 IFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLR-RQNFPIKGAXXXXXXXXXXXXXXXX----XXXXXTEYKTINESDF--CSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESI-----RSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIY-LTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTC 1057
            +F L + GN  V ++++ R    +  ++F+ +L+++DL + +FC+P+T   +  F  WI G A+C + PF+Q  +V  S +T   I+V+R+  + HPLR R  +    A  ++  +W+  + ++            Y  + +     CSE+W    +   Y+  ++++ + LP++ +   Y+ +A  LW      +++     RS    I  SKK+ +KM +IV I +++   P H++  L  K ++  S    +D   +T L    L   S   +NPI+Y  LN +++K L   L+C
Sbjct:   55 VFTLALSGNALVIFVVARRKALHTVANVFVCSLAVSDLMITVFCIPITLMQN-FFSNWIAGVALCKLVPFIQVTAVTTSMLTMACIAVERFQGILHPLRSRSRYTTARAASMLCGVWLVGLCVAAPMFYAHTVQVTYDVLYDVSHTGCSEQWSHAEHRQAYTTTLLLVTFVLPLLTMTALYTRLAHELWVKTRVHDAVFNALQRSEINKITRSKKRAVKMMVIVVILFAVCWAPFHVVNSLVPKGNLEMS----FDMEAIT-LAMVQLFGFSNSLWNPIVYAALNQNYKKQLAIALSC 346          
BLAST of Neuropeptide receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010661.1 (pep scaffold:Pmarinus_7.0:GL479584:296:6514:-1 gene:ENSPMAG00000009652.1 transcript:ENSPMAT00000010661.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 110.923 bits (276), Expect = 3.553e-28
Identity = 84/277 (30.32%), Postives = 139/277 (50.18%), Query Frame = 2
Query:  212 ILGVVGNLAVCYIIS-CRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKT----INESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSF 1027
            +L + GN  V ++++  R  ++  S FL+NL+LADL MALFC+P TF ++ +   W+FG  +C +  F Q LSV +S  T T I +DRY+ V HPL  +    +G V +     +               +     + +       WP+   +  Y++ +++  Y LP++V+ + YS++A+RLW  +TPG    +R+     SK+K+  +     IF  +  +    IY+ S        +P W    V IL F   LS+S+    P L +W +SSF
Sbjct:   11 VLALSGNAVVVWVLALGRRARTDISAFLINLALADLTMALFCLPFTF-TEVLLQSWLFGALLCPLVRFAQTLSVSVSIYTLTTIGIDRYYAVCHPLHSRMTKSRGKVLIALIWAVSISISLSTTTLAVATRGPMLQLGKGKCLEVGWPSRGYQQSYTVALLLGTYLLPLLVLTLAYSSVAVRLWGRRTPGNVDHNRELHQERSKRKLCHLVFFPTIFVVVVVVVLIEIYIES----DKRGDPGW-LRGVQILAFN--LSISSPIMKPGLQIWQHSSF 279          
BLAST of Neuropeptide receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008040.1 (pep scaffold:Pmarinus_7.0:GL477351:476361:492361:-1 gene:ENSPMAG00000007251.1 transcript:ENSPMAT00000008040.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 102.449 bits (254), Expect = 1.905e-24
Identity = 85/296 (28.72%), Postives = 142/296 (47.97%), Query Frame = 2
Query:  167 PYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF----CSEKWPTE---NNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFR 1030
            P+   ++   Y  I  +   GN+ V +I+    R ++ T+ FL+NL++AD  MA     + F    +   W FG A C    F+   +VF S  + TAI+VDRY  + HPL+    P   A      +           + ++ Y  + E  F    C   WP +   +++ +Y L VM L Y  P++V+ +TY+ + + LW    PG+S     E +  SK+K++KM I+V + +++  +P H+ +L  +         +     + I      L+MS+  YNPI+Y  LNS FR
Sbjct:   54 PWQVALWSVAYGGIVAVAFFGNMVVIWIVVAHRRMRTVTNYFLVNLAVADSAMAALNTSINFVY-AVHNDWYFGGAYCRFQNFIPVAAVFASIYSMTAIAVDRYMAIRHPLK----PRMTAQSTRLVMAGIWALAMCLSLPLSIYSRV-EQRFGRFVCLVDWPGKMGGDSQFIYQLVVMTLVYVFPLLVMAVTYTIVGVTLWGGTIPGDSSEHFREQL-RSKRKVVKMMIVVVVTFAVCWMPYHVYFLLGRTLNRIYHRKYIQQVYLAIF----WLAMSSTMYNPIIYCCLNSRFR 338          
BLAST of Neuropeptide receptor vs. Ensembl Sea Lamprey
Match: galr2a (galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-130603-37])

HSP 1 Score: 100.523 bits (249), Expect = 4.733e-24
Identity = 84/287 (29.27%), Postives = 135/287 (47.04%), Query Frame = 2
Query:  197 YVSIFILGVVGNLAVCYIISCRLRQSA----TSIFLLNLSLADLKMALFCVPVTFFSDCIFM--RWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNF--PIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
            ++ IF+LG  GN  V  ++ C  ++ +    T+IF+LNLS+ADL   LFCVP   F   I+    WIFG  +C    F+  L++F SS T  A+SVDRY  + +PLR +    P K A  + +   +  +     L +  +  T      C   W  E  +++  +   V  Y +P+ V+ + Y+     LW    P E +         +K+K+  M +IVA  +    LP H++ L   F       P   +T    L  +H +S +    NP++Y  ++  FRK
Sbjct:   32 FLLIFLLGAFGNSLVIIVLLCSGQRGSSNTTTNIFILNLSVADLCFILFCVP---FQATIYTLDGWIFGSFLCKAVHFIIFLTMFASSFTLAAVSVDRYLAIRYPLRSRELRTPRKAAAVIAAIWGLALVFAGPYLSYY-QAVTFQNMSMCMPVWAKEPRKLM-DMVTFVCGYLVPVSVLGLAYAFTLKYLWTAVDPLEEMSESKR----AKRKVTTMILIVAGLFCACWLPHHVLILYFWF----GHFPLTHATYAFRL-LSHCMSYANSCLNPLVYALVSKHFRK 304          
BLAST of Neuropeptide receptor vs. Ensembl Nematostella
Match: EDO36453 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIH9])

HSP 1 Score: 121.324 bits (303), Expect = 2.225e-31
Identity = 84/292 (28.77%), Postives = 144/292 (49.32%), Query Frame = 2
Query:  170 YLQYIYGFFYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQ-NPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTL 1039
            +L+ I    Y  IF++   GN  VC +I  R + ++ T+ F+LNL++ADL +   C+P       +   W +G  MC V   +Q L++F S  T TA+S+ RY+ + HPLR+Q   +  A  +V  IW+ S+    P +    Y  +  S +C E W   N    Y+  +   QY +P+ +I   Y +I   L         +R++        KK+++M +IV + +++  LP ++++L   F  +      FWD     ++ F H+ +      NPI Y  LN ++RK +
Sbjct:   33 HLRTIKLTLYTLIFLVSAAGNTLVCIVILKRKKMKTVTNYFILNLAVADLALTCICIPFDIPVQEMGYIWPYGAVMCKVLYPLQTLTLFASVYTLTAVSLTRYWAIVHPLRKQ-LSVSKAKTLVIAIWVLSLLPVAPYMNSLSY--VPHSKYCEENWDNHNARKGYTASLFAFQYVIPLTIIATAYCSITRELSRRTIESACVRNQQH---KETKKVVRMLMIVTLLFAVCVLPNNVMWLWLDFGAADKSFKYFWD-----VVAFCHVWTFLNSAANPICYTILNENYRKEI 313          
BLAST of Neuropeptide receptor vs. Ensembl Nematostella
Match: EDO27481 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T950])

HSP 1 Score: 120.168 bits (300), Expect = 3.834e-31
Identity = 84/292 (28.77%), Postives = 144/292 (49.32%), Query Frame = 2
Query:  170 YLQYIYGFFYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQ-NPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTL 1039
            +L+ I    Y  IF++   GN  VC +I  R + ++ T+ F+LNL++ADL +   C+P       +   W +G  MC V   +Q L++F S  T TA+S+ RY+ + HPLR+Q   +  A  +V  IW+ S+    P +    Y  +  S +C E W   N    Y+  +   QY +P+ +I   Y +I   L         +R++        KK+++M +IV + +++  LP ++++L   F  +      FWD     ++ F H+ +      NPI Y  LN ++RK +
Sbjct:    1 HLRTIKLTLYTLIFLVSAAGNTLVCIVILKRKKMKTVTNYFILNLAVADLALTCICIPFDIPVQEMGYIWPYGAVMCKVLYPLQTLTLFASVYTLTAVSLTRYWAIVHPLRKQ-LSVSKAKTLVIAIWVLSLLPVAPYMNSLSY--VPHSKYCEENWDNHNARKGYTASLFAFQYVIPLTIIATAYCSITSELSRRTIESACVRNQQH---KETKKVVRMLMIVTLLFAVCVLPNNVMWLWLDFGAADKSFKYFWD-----VVAFCHVWTFLNSAANPICYTILNENYRKEI 281          
BLAST of Neuropeptide receptor vs. Ensembl Nematostella
Match: EDO40944 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5Q4])

HSP 1 Score: 114.775 bits (286), Expect = 2.744e-29
Identity = 89/280 (31.79%), Postives = 149/280 (53.21%), Query Frame = 2
Query:  200 VSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQ-NPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
            V IF++  VGN  VC +I  R R ++ T+ F+LNL++ADL +   C+P       +   W +G  MC +   +Q LS+F S  T TA+S+ RY+ + HPLR+Q   +  +  ++  IW+ SI    P  +V  ++  + S  C E W   +   +Y+  + + QY LP+ VI   Y  I I L   QT   S   RD V A   +K+++M  +V + +++  LP +I++L   F  +  + + FWD     ++ F ++++ +    NPI Y  LN ++RK
Sbjct:    1 VIIFLISAVGNSLVCIVILRRRRMKTVTNYFVLNLAIADLALTCICIPFDIPVQEMNYVWPYGGFMCKILYPLQTLSLFASVFTLTAVSLTRYWAIVHPLRQQ-LSVSNSKRIIVAIWVISIIPVSPYSYVLSHE--DGSLSCEENWGDTSMRKVYTAVLFMFQYVLPLTVIAGAYIGIGIELRKRQTRDRSGGLRD-VHAEETRKVLRMLKVVTVVFAVFVLPTNIMWLWLDFGHAEQEYDRFWD-----LVAFCNIVTFANSAANPICYTVLNETYRK 271          
BLAST of Neuropeptide receptor vs. Ensembl Nematostella
Match: EDO36473 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIH8])

HSP 1 Score: 114.775 bits (286), Expect = 2.800e-29
Identity = 76/282 (26.95%), Postives = 140/282 (49.65%), Query Frame = 2
Query:  194 FYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQ-NPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRK 1033
             Y +IF++  VGN  VC II  R + ++ T+ F+LNL++ADL +   C+P       +   W +G  MC V   +Q L++F S  T TA+ + RY+ + HP++RQ   +      +   +I+  S+     +    K   E+  C E W ++    +++  + V QY LP+ VI   Y+AI   L   +           + A   +K++ M  +V + +++  LP +I++L   F  +  +   FW+     I+ F ++++ +    NP+ Y  LN ++R+
Sbjct:   13 LYAAIFLISAVGNTMVCAIIVRRKKMKTVTNYFILNLAVADLALTCICIPFDIPVQEMGYIWPYGAVMCKVLYPLQTLTLFASVYTLTAVGLTRYWAIVHPMKRQ---LSITQSKLVIAFIWLGSVVPVFPYANSLKFTRETHTCEEYWSSKKVREIFTAVIFVFQYVLPLGVIGTAYAAIGRELRRRKATKSGNHKLRHLQAQEARKVVNMLSVVTMVFAICVLPNNIMWLWLDFGDADQKVEYFWE-----IVAFCNVVTFANSAANPVCYTALNETYRR 286          
BLAST of Neuropeptide receptor vs. Ensembl Nematostella
Match: EDO46084 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR06])

HSP 1 Score: 115.931 bits (289), Expect = 4.536e-29
Identity = 84/291 (28.87%), Postives = 141/291 (48.45%), Query Frame = 2
Query:  194 FYVSIFILGVVGNLAVCYIISCRLR-QSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVT-ILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCN 1060
             Y  IF++  VGN  VC +I+ R R ++ T+ F+LNL++ADL + L C+P          +W +G  MC +   +Q + +F S  T  A+S++R++ + +PLR Q      A  ++  IW  S  ++ P + V E K     D CSE WP       Y+  + V+QY LP+ +I   Y  I   L        +  + +       +K+++M IIV + +++  LP ++++L   F         W+   VT I+ FA+  +      NP+ Y   N  FR+      TC+
Sbjct:   41 LYALIFLISTVGNSLVCIVIARRRRMRTVTNYFILNLAIADLAITLICIPFDIPVQENGYKWPYGAFMCKIMYPLQTMCMFASIFTLVAVSLNRFWAIVYPLR-QEMSKSQATIIIILIWFISSGLTVPYVTVLELKN---GDDCSESWPEPGYRKAYTACIFVVQYLLPLTLIAFAYLKIGFELRKCVGTRTANSALERAKQEDTRKVVRMLIIVTLLFAMCVLPNNVMWLWLDFGNGNDYEHIWEMVAVTNIILFANSAT------NPVAYTICNERFREEFRLYFTCD 321          
BLAST of Neuropeptide receptor vs. Ensembl Medaka
Match: ENSORLT00000008966.2 (prolactin-releasing peptide receptor-like [Source:NCBI gene;Acc:101165331])

HSP 1 Score: 125.176 bits (313), Expect = 5.114e-32
Identity = 94/297 (31.65%), Postives = 150/297 (50.51%), Query Frame = 2
Query:  194 FYVSIFILGVVGN--LAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESD----FCSEKWPTENN-EMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNF----AHLLSMSACFYNPILYVWLNSSFRKTLTNML 1051
             Y  + ++  VGN  L  C +   +L  +AT+ F+ NL+  DL M L CVP+T         W FGR++CH+ P +Q  +VF S+++ TAI+VDRY VV HP+RR+   +     V   +W+ S++++ P  F T Y  +  S      C E WP   N  +LYS F++   Y +P++ + M+Y AI + L  Y  PGE   S+    +  ++K   + +   + ++L  LP  ++ L          +P +       +N      HLL+MS+  YNP +Y  L+S  R  L   L
Sbjct:   55 LYCLVVVVAGVGNSILLACIMADKKL-HNATNFFIGNLAAGDLLMCLSCVPLTASYAFDSHGWAFGRSLCHLVPLLQCATVFASALSLTAIAVDRYIVVAHPVRRR-ISVWSCGAVTLGVWLLSLTLAAPPSFYTSYVDLRPSGVNLVVCEEFWPNNGNLRLLYSCFILSTSYMIPLLSVSMSYCAITVSLKRYSVPGEQSISQQR-WSKRRRKTFSLLVASVLAFALCWLPLQVLNLMMDL------DPDFLIIGKRYINLLQVCCHLLAMSSSCYNPFIYASLHSKVRMHLKGYL 342          
BLAST of Neuropeptide receptor vs. Ensembl Medaka
Match: npy7r (PRELI domain-containing protein 1, mitochondrial [Source:NCBI gene;Acc:101174272])

HSP 1 Score: 121.709 bits (304), Expect = 1.202e-30
Identity = 93/295 (31.53%), Postives = 148/295 (50.17%), Query Frame = 2
Query:  227 GNLAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYF-VVFHPLRRQNFP---IKGAXXXXXXXXXXXXXXXXXXXXXTEYKTIN-ESDFCSEKWP--TENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTC-NKSSSLPPTS 1087
             +L +  II  R  ++ T+ F+ NL+LADL +   C+P T     +   W FG  +CH+ PF QALSV +S +T T I+++RY  +VFH  RR  +    +  A        + +    F      E  +IN     CSEKWP  T  + ++YSLF+++LQY +P+ VI   Y  I ++L  + +P     SR++ I   +KK  KM  +V + ++   LP H+  L S   +      +    TV      H+++M + F NP+LY W+N ++R     +  C +K  S  P  
Sbjct:   62 NSLVIYMIIRYRNMRTVTNFFIANLALADLLVNTLCLPFTLVY-TLLDEWKFGAVLCHMVPFAQALSVHVSILTLTVIALERYRCIVFHLGRRLTWHSSLLIMAFTWTVSAVLAAPLAIFREYRQEEIPSINLRIAVCSEKWPHGTSRDGVIYSLFMLLLQYIIPLAVISYAYICIWVKLKNHISPS----SRNDNI-NRRKKTTKMLALVVVVFATCWLPFHVFQLASDLDLVLRFEEYKFIYTV-----FHVVAMCSTFANPLLYGWMNKNYRNGFLMVFRCEDKPESFHPEG 345          
BLAST of Neuropeptide receptor vs. Ensembl Medaka
Match: npy2rl (neuropeptide Y receptor type 2 [Source:NCBI gene;Acc:101162714])

HSP 1 Score: 122.094 bits (305), Expect = 1.666e-30
Identity = 95/334 (28.44%), Postives = 166/334 (49.70%), Query Frame = 2
Query:  104 LPAMLPLNQSNFSLPFSDILFPYLQYIYGFFYVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYF-VVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTI-----NESDFCSEKWPTENNE-MLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESI--RSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTIL-NFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSS 1072
            LPA LP      S P   I    +Q +    Y +I +LGV+GN  V Y+I   +  ++ T+ F+ NL++ADL +   C+P T     +   W FG  +C + P+ Q L+V +S+VT   I++DR+  +V+H   R    +     V++  W+ S  ++ PL    EY +      +    C+EKWP ++ +  +YS+ +++LQYFLP+ +I   Y+ I  +L  + +P E     S        ++K  KM + + + +++S LP H   L +        N   D     +L    H+++M + F NP+LY W+N ++R     +  C + + 
Sbjct:   39 LPA-LPTGFEGVSFPEDPIRLLSVQVVLILAYSTIIVLGVLGNSLVIYVIYRFKTLRTVTNFFIANLAVADLLVNTLCLPFTLVY-TLQGEWKFGSTLCFLLPYAQGLAVHVSTVTLNVIALDRHRCIVYHLETRMRKDV--CFGVIALTWVLSAVLASPLAIFREYGSFTLEPGHTIQVCTEKWPGKSTDGTIYSISMLILQYFLPLSIISFAYARIWSKLRGHVSPAEGGANSSAGSERHRRRRKTTKMLVTMVVVFAVSWLPFHAFQLATDI-----DNKVLDMRDFRLLYTIFHVVAMCSTFANPLLYGWMNRNYRAAFLAVFKCRRGAD 363          
BLAST of Neuropeptide receptor vs. Ensembl Medaka
Match: npy2rl (neuropeptide Y receptor type 2 [Source:NCBI gene;Acc:101162714])

HSP 1 Score: 122.094 bits (305), Expect = 1.666e-30
Identity = 95/334 (28.44%), Postives = 166/334 (49.70%), Query Frame = 2
Query:  104 LPAMLPLNQSNFSLPFSDILFPYLQYIYGFFYVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYF-VVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTI-----NESDFCSEKWPTENNE-MLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESI--RSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTIL-NFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSS 1072
            LPA LP      S P   I    +Q +    Y +I +LGV+GN  V Y+I   +  ++ T+ F+ NL++ADL +   C+P T     +   W FG  +C + P+ Q L+V +S+VT   I++DR+  +V+H   R    +     V++  W+ S  ++ PL    EY +      +    C+EKWP ++ +  +YS+ +++LQYFLP+ +I   Y+ I  +L  + +P E     S        ++K  KM + + + +++S LP H   L +        N   D     +L    H+++M + F NP+LY W+N ++R     +  C + + 
Sbjct:   39 LPA-LPTGFEGVSFPEDPIRLLSVQVVLILAYSTIIVLGVLGNSLVIYVIYRFKTLRTVTNFFIANLAVADLLVNTLCLPFTLVY-TLQGEWKFGSTLCFLLPYAQGLAVHVSTVTLNVIALDRHRCIVYHLETRMRKDV--CFGVIALTWVLSAVLASPLAIFREYGSFTLEPGHTIQVCTEKWPGKSTDGTIYSISMLILQYFLPLSIISFAYARIWSKLRGHVSPAEGGANSSAGSERHRRRRKTTKMLVTMVVVFAVSWLPFHAFQLATDI-----DNKVLDMRDFRLLYTIFHVVAMCSTFANPLLYGWMNRNYRAAFLAVFKCRRGAD 363          
BLAST of Neuropeptide receptor vs. Ensembl Medaka
Match: npy2rl (neuropeptide Y receptor type 2 [Source:NCBI gene;Acc:101162714])

HSP 1 Score: 117.472 bits (293), Expect = 3.592e-29
Identity = 89/320 (27.81%), Postives = 162/320 (50.62%), Query Frame = 2
Query:  146 PFSDILFPYLQYIYGFFYVSIFILGVVGNLAVCYII-SCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYF-VVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTI-----NESDFCSEKWPTENNE-MLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGE--SIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTIL-NFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSS 1072
            PF+      L+ +    Y +I +LGV+GN  V Y+I   +  ++ T+ F+ NL++ADL +   C+P T     +   W FG  +C + P+ Q L+V +S+VT   I++DR+  +V+H   R    +     V++  W+ S  ++ PL    EY +      +    C+EKWP ++ +  +YS+ +++LQYFLP+ +I   Y+ I  +L  + +P E  +  S        ++K  KM + + + +++S LP H   L +        N   D     +L    H+++M + F NP+LY W+N ++R     +  C + + 
Sbjct:   40 PFTSSALVCLKVVLILAYSTIIVLGVLGNSLVIYVIYRFKTLRTVTNFFIANLAVADLLVNTLCLPFTLVYT-LQGEWKFGSTLCFLLPYAQGLAVHVSTVTLNVIALDRHRCIVYHLETRMRKDV--CFGVIALTWVLSAVLASPLAIFREYGSFTLEPGHTIQVCTEKWPGKSTDGTIYSISMLILQYFLPLSIISFAYARIWSKLRGHVSPAEGGANSSAGSERHRRRRKTTKMLVTMVVVFAVSWLPFHAFQLATDI-----DNKVLDMRDFRLLYTIFHVVAMCSTFANPLLYGWMNRNYRAAFLAVFKCRRGAD 351          
BLAST of Neuropeptide receptor vs. Planmine SMEST
Match: SMESG000017198.1 (SMESG000017198.1)

HSP 1 Score: 685.641 bits (1768), Expect = 0.000e+0
Identity = 362/362 (100.00%), Postives = 362/362 (100.00%), Query Frame = 2
Query:  113 MLPLNQSNFSLPFSDILFPYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSPKCISAFPDGYSSKKRMLSISSNNALFNAKLHERRFL 1198
            MLPLNQSNFSLPFSDILFPYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAVFVVSCIWIFSISISFPLIFVTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSPKCISAFPDGYSSKKRMLSISSNNALFNAKLHERRFL
Sbjct:    1 MLPLNQSNFSLPFSDILFPYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAVFVVSCIWIFSISISFPLIFVTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSPKCISAFPDGYSSKKRMLSISSNNALFNAKLHERRFL 362          
BLAST of Neuropeptide receptor vs. Planmine SMEST
Match: SMESG000016672.1 (SMESG000016672.1)

HSP 1 Score: 223.016 bits (567), Expect = 6.869e-70
Identity = 128/305 (41.97%), Postives = 194/305 (63.61%), Query Frame = 2
Query:  128 QSNFSLPFSDILFPYLQYIYGFFYVSIFILGVVGNLAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINES-DFCSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTV-TILNFAHLLSMSACFYNPILYVWLNSSFRKT 1036
             +++S P  D+   Y + ++   +  +FI+G+ GN  +C+I+   + ++AT+IFL NLSLAD+ M L C PVT  SD +   W FG  +C V PF+Q +SVFLS +TH  IS DR+ VVF P++ +    + +  ++   WI SI +S PL+ V E  TIN++ D C E W  +++ ++Y+  V++ QYFLP+  I  TY AIA++LW  + PG S   R+E +  SKK+M+KM IIVA FYSLSQLPRH+++L     +  S   F+ S  V  +L F+H LS+SA  YN  +Y+WLN +F+++
Sbjct:    2 NNSYSSPVQDVSV-YYKVLFSILFSIVFIVGIGGNYCICWILIKDINRNATNIFLFNLSLADILMCLICSPVTLVSDGLLFYWPFGSLLCKVVPFIQGISVFLSGLTHVVISSDRFVVVFFPMKTR-LSNECSWGLIGLTWIISIILSLPLVIVNEISTINQNRDLCEENWKNKDHGLIYTFVVLICQYFLPVAFITSTYIAIAVKLWIRKPPGVSFPGRNEQVNNSKKRMVKMVIIVASFYSLSQLPRHVLFL-----IGYSNELFFSSKHVKELLLFSHFLSISATTYNIFIYLWLNRNFKES 299          
BLAST of Neuropeptide receptor vs. Planmine SMEST
Match: SMESG000016225.1 (SMESG000016225.1)

HSP 1 Score: 197.593 bits (501), Expect = 8.934e-59
Identity = 132/349 (37.82%), Postives = 192/349 (55.01%), Query Frame = 2
Query:  188 GFFYVSIFILGVVGNLAVCYIISCRLRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLR---RQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDFCSEKW---------PTENNE------MLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTNMLTCNKSSSLPPTSPKCISAFP--------DGYSSKKRMLSISSN 1156
            G    ++ + GV+GN +VCY+I   L+ S T++FLLNLSLAD+ +A+F  P    +D I   W FG AMC + P VQ +S F+S+ TH  IS DR+ VVF PL+   RQ    K A+F++S IWIFS  +  PL  V + +    + +C E W         P    E       +Y++ +MVLQ+FLP+ VII TYSAIA R+W  +TPGE    RD+ IA SK+K++KM IIVA+ Y LS+LPRH ++L S    +   N  +    + +  F  L   S+  +NP++Y W+N  FR+    +           T P C++  P          Y + +   ++SSN
Sbjct:   33 GIALSAVIVWGVIGNASVCYVIIKDLKLSVTNLFLLNLSLADILIAIFSGPFVMLNDFIIGHWTFGVAMCKLMPLVQGISSFVSAFTHVVISFDRFVVVFRPLKPRIRQ----KSAMFILSTIWIFSALVVVPLPIVYDVRFDGNNGYCLEDWSIFVNGNYSPDTIKEKATYRNFIYTILLMVLQFFLPLTVIIGTYSAIAFRIWIRETPGEVDLKRDQRIAKSKRKLLKMVIIVALLYGLSRLPRHALFLAS-LKYTEMWNAGYSHYVLYVWLFCILAEQSSMGFNPLIYFWMNKLFRRGFIQICI--------DTVPCCVNRSPCCTRSIENHHYPTDRNTYNLSSN 368          
BLAST of Neuropeptide receptor vs. Planmine SMEST
Match: SMESG000035936.1 (SMESG000035936.1)

HSP 1 Score: 127.487 bits (319), Expect = 2.291e-32
Identity = 86/279 (30.82%), Postives = 148/279 (53.05%), Query Frame = 2
Query:  227 GNLAVC---YIISCR-LRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF--CSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFRKTLTN 1045
            GN+ V    ++ +CR  R +    FL NL+++DL ++LFCVP TF +  +   W F    C V   +Q L+V  SS+T+  I +DR++VV +P++ +    +    +V      S  +   +       +I E  +  CSE W   N ++ Y++ ++++ YFLP+IV+ +TY+ + I+LW    PGE+   RD     SK K+IKM  I+ I + L  LP H+ ++ +  + S       +   V      H ++MS  F NP++Y ++N SF++ + N
Sbjct:   45 GNVVVIIVFWLGTCRPNRNNEVRQFLTNLAVSDLLISLFCVPFTF-TYILLWDWPFPYLFCPVVLSIQLLAVTASSITNMVIGLDRFWVVIYPMKSR--ITRKRSGLVIGCIWVSSILFSSVQCFVSRASIREGGYTECSENWNNNNLQISYTISILLITYFLPLIVLTVTYTIVGIKLWKRSLPGEADEIRDAKHMKSKVKVIKMLSIIVICFGLCWLPLHLFFVVTHVNQSQGYTKNLNIAYVV----CHWIAMSNSFVNPVVYSFMNDSFKELVYN 316          
BLAST of Neuropeptide receptor vs. Planmine SMEST
Match: SMESG000035936.1 (SMESG000035936.1)

HSP 1 Score: 126.331 bits (316), Expect = 6.039e-32
Identity = 85/274 (31.02%), Postives = 145/274 (52.92%), Query Frame = 2
Query:  227 GNLAVC---YIISCR-LRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPFVQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAXXXXXXXXXXXXXXXXXXXXXTEYKTINESDF--CSEKWPTENNEMLYSLFVMVLQYFLPIIVIIMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQLPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVWLNSSFR 1030
            GN+ V    ++ +CR  R +    FL NL+++DL ++LFCVP TF +  +   W F    C V   +Q L+V  SS+T+  I +DR++VV +P++ +    +    +V      S  +   +       +I E  +  CSE W   N ++ Y++ ++++ YFLP+IV+ +TY+ + I+LW    PGE+   RD     SK K+IKM  I+ I + L  LP H+ ++ +  + S       +   V      H ++MS  F NP++Y ++N SF+
Sbjct:   45 GNVVVIIVFWLGTCRPNRNNEVRQFLTNLAVSDLLISLFCVPFTF-TYILLWDWPFPYLFCPVVLSIQLLAVTASSITNMVIGLDRFWVVIYPMKSR--ITRKRSGLVIGCIWVSSILFSSVQCFVSRASIREGGYTECSENWNNNNLQISYTISILLITYFLPLIVLTVTYTIVGIKLWKRSLPGEADEIRDAKHMKSKVKVIKMLSIIVICFGLCWLPLHLFFVVTHVNQSQGYTKNLNIAYVV----CHWIAMSNSFVNPVVYSFMNDSFK 311          
The following BLAST results are available for this feature:
BLAST of Neuropeptide receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NPFFR21.375e-3030.00neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc... [more]
NPFFR21.486e-3030.00neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc... [more]
NPFFR27.430e-3030.31neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc... [more]
QRFPR1.645e-2927.21pyroglutamylated RFamide peptide receptor [Source:... [more]
NPY2R2.274e-2728.39neuropeptide Y receptor Y2 [Source:HGNC Symbol;Acc... [more]
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BLAST of Neuropeptide receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
npr-61.095e-3028.62NeuroPeptide Receptor family [Source:UniProtKB/Tr... [more]
npr-223.708e-3030.40Neuropeptide receptor 22 [Source:UniProtKB/Swiss-... [more]
npr-221.184e-2831.21Neuropeptide receptor 22 [Source:UniProtKB/Swiss-... [more]
npr-22.164e-2524.64NeuroPeptide Receptor family [Source:UniProtKB/Tr... [more]
npr-23.220e-2524.64NeuroPeptide Receptor family [Source:UniProtKB/Tr... [more]
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BLAST of Neuropeptide receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RYa-R1.375e-5035.22gene:FBgn0004842 transcript:FBtr0085100[more]
RYa-R1.875e-5035.22gene:FBgn0004842 transcript:FBtr0345268[more]
RYa-R9.380e-5035.22gene:FBgn0004842 transcript:FBtr0345267[more]
Lkr4.026e-3030.74gene:FBgn0035610 transcript:FBtr0077149[more]
TkR99D7.933e-3029.14gene:FBgn0004622 transcript:FBtr0301656[more]
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BLAST of Neuropeptide receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
npy7r1.967e-3030.79neuropeptide Y receptor Y7 [Source:ZFIN;Acc:ZDB-GE... [more]
prlhr2a3.270e-3027.92prolactin releasing hormone receptor 2a [Source:ZF... [more]
CU915819.23.300e-2930.03neuropeptide FF receptor 2a [Source:NCBI gene;Acc:... [more]
AL929374.13.300e-2930.03neuropeptide FF receptor 2a [Source:NCBI gene;Acc:... [more]
NPFFR23.300e-2930.03neuropeptide FF receptor 2a [Source:NCBI gene;Acc:... [more]
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BLAST of Neuropeptide receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GPR831.586e-3529.53G protein-coupled receptor 83 [Source:NCBI gene;Ac... [more]
ENSXETT00000044281.11.187e-3128.80pep primary_assembly:Xenopus_tropicalis_v9.1:3:115... [more]
gamt6.031e-3029.84guanidinoacetate N-methyltransferase [Source:Xenba... [more]
taf1b1.385e-2929.19TATA-box binding protein associated factor, RNA po... [more]
clstn22.315e-2730.43calsyntenin 2 [Source:Xenbase;Acc:XB-GENE-958942][more]
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BLAST of Neuropeptide receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Npy2r1.351e-2829.90neuropeptide Y receptor Y2 [Source:MGI Symbol;Acc:... [more]
Npy2r1.351e-2829.90neuropeptide Y receptor Y2 [Source:MGI Symbol;Acc:... [more]
Npy2r1.351e-2829.90neuropeptide Y receptor Y2 [Source:MGI Symbol;Acc:... [more]
Npffr21.037e-2726.84neuropeptide FF receptor 2 [Source:MGI Symbol;Acc:... [more]
Tacr21.927e-2729.05tachykinin receptor 2 [Source:MGI Symbol;Acc:MGI:9... [more]
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BLAST of Neuropeptide receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P25931|RYAR_DROME1.379e-4935.22RYamide receptor OS=Drosophila melanogaster OX=722... [more]
sp|G4WMX4|RYAR_TRICA8.227e-3732.88RYamide receptor OS=Tribolium castaneum OX=7070 GN... [more]
sp|Q9DDN6|NPY2R_CHICK3.648e-3028.79Neuropeptide Y receptor type 2 OS=Gallus gallus OX... [more]
sp|Q9Y5X5|NPFF2_HUMAN3.568e-2930.31Neuropeptide FF receptor 2 OS=Homo sapiens OX=9606... [more]
sp|P05363|NK2R_BOVIN6.087e-2930.95Substance-K receptor OS=Bos taurus OX=9913 GN=TACR... [more]
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BLAST of Neuropeptide receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A193KUS42.524e-6641.97GCR337 OS=Schmidtea mediterranea OX=79327 GN=gcr33... [more]
R7TR011.856e-5437.91G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A210Q9U71.631e-5233.43Neuropeptide Y receptor OS=Mizuhopecten yessoensis... [more]
V3ZSY84.808e-5236.51G_PROTEIN_RECEP_F1_2 domain-containing protein (Fr... [more]
A0A0R3TQ591.434e-5137.33G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
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BLAST of Neuropeptide receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
npy2rl1.122e-3028.38neuropeptide Y receptor type 2-like [Source:NCBI g... [more]
npy2r1.772e-3028.91neuropeptide Y receptor Y2 [Source:ZFIN;Acc:ZDB-GE... [more]
prlhr2b1.864e-3028.53prolactin-releasing peptide receptor-like [Source:... [more]
prlhr2b2.104e-3028.53prolactin-releasing peptide receptor-like [Source:... [more]
QRFPR2.947e-3027.33pyroglutamylated RFamide peptide receptor-like [So... [more]
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BLAST of Neuropeptide receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prlh2r3.417e-3629.65prolactin releasing hormone 2 receptor [Source:ZFI... [more]
qrfpr46.592e-2926.51pyroglutamylated RFamide peptide receptor 4 [Sourc... [more]
ENSPMAT00000010661.13.553e-2830.32pep scaffold:Pmarinus_7.0:GL479584:296:6514:-1 gen... [more]
ENSPMAT00000008040.11.905e-2428.72pep scaffold:Pmarinus_7.0:GL477351:476361:492361:-... [more]
galr2a4.733e-2429.27galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-1306... [more]
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BLAST of Neuropeptide receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Neuropeptide receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO364532.225e-3128.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO274813.834e-3128.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO409442.744e-2931.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO364732.800e-2926.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO460844.536e-2928.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Neuropeptide receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000008966.25.114e-3231.65prolactin-releasing peptide receptor-like [Source:... [more]
npy7r1.202e-3031.53PRELI domain-containing protein 1, mitochondrial [... [more]
npy2rl1.666e-3028.44neuropeptide Y receptor type 2 [Source:NCBI gene;A... [more]
npy2rl1.666e-3028.44neuropeptide Y receptor type 2 [Source:NCBI gene;A... [more]
npy2rl3.592e-2927.81neuropeptide Y receptor type 2 [Source:NCBI gene;A... [more]
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BLAST of Neuropeptide receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000017198.10.000e+0100.00SMESG000017198.1[more]
SMESG000016672.16.869e-7041.97SMESG000016672.1[more]
SMESG000016225.18.934e-5937.82SMESG000016225.1[more]
SMESG000035936.12.291e-3230.82SMESG000035936.1[more]
SMESG000035936.16.039e-3231.02SMESG000035936.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004873 ID=SMED30004873|Name=Neuropeptide receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1236bp
GTCAATGAATCACAATTCACAGAACAGCTGCTATTGGTCGCCTGATCGGC
CAATAGCAGCAGTTCTCATCAATCCACTATTGTCGCATTTTTAATGTCCC
ACATTACCGGCAATGTTACCTTTGAATCAGTCGAATTTCAGCTTACCTTT
CAGTGATATTCTGTTTCCTTATCTTCAATACATTTATGGCTTCTTTTACG
TTTCGATATTTATCCTTGGAGTTGTCGGCAATTTGGCCGTTTGTTACATA
ATCTCTTGCCGTTTGCGGCAGTCAGCCACCTCGATATTTTTACTGAATCT
CAGTTTGGCCGATTTGAAAATGGCCCTATTTTGTGTTCCGGTCACATTTT
TCTCCGACTGCATCTTTATGAGATGGATTTTCGGACGAGCAATGTGCCAC
GTATTTCCTTTCGTGCAAGCTCTCAGTGTTTTCCTCAGTTCCGTTACTCA
CACGGCAATATCGGTTGACAGATATTTCGTGGTGTTCCATCCGTTGAGAC
GCCAGAATTTCCCGATCAAAGGCGCAGTTTTCGTTGTCAGTTGCATCTGG
ATATTTTCCATTTCAATAAGCTTTCCTCTCATCTTTGTCACGGAATACAA
GACAATTAATGAAAGCGATTTCTGTTCGGAGAAGTGGCCAACGGAAAATA
ACGAAATGCTATATTCGCTGTTTGTGATGGTTTTGCAATATTTCCTGCCG
ATTATCGTCATCATTATGACATATTCTGCTATCGCGATCCGGCTCTGGTT
CTATCAGACCCCTGGAGAATCTATCCGGTCGAGAGATGAAGTCATTGCCA
CATCGAAAAAGAAGATGATCAAAATGTTCATCATCGTTGCAATCTTCTAC
TCGTTGAGCCAGCTGCCCAGGCACATTATCTATTTGACGTCGAAGTTCTC
CGTATCAACGAGCCAGAATCCGTTTTGGGATTCCACGACCGTCACCATTC
TTAATTTCGCTCATCTACTCAGCATGAGCGCTTGCTTCTACAACCCGATT
CTCTACGTTTGGCTGAACTCCTCGTTTCGGAAAACCTTAACGAATATGTT
GACCTGCAACAAGTCATCGAGTTTGCCGCCAACGTCTCCAAAATGTATCT
CAGCATTCCCGGACGGATATTCCTCGAAGAAAAGAATGCTCAGCATTAGT
TCAAACAATGCATTGTTCAATGCAAAGCTACATGAGCGTCGTTTTTTATG
AAGACGAATTATTTCGACAGATATACTGATGAAAAT
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protein sequence of SMED30004873-orf-1

>SMED30004873-orf-1 ID=SMED30004873-orf-1|Name=SMED30004873-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=363bp
MLPLNQSNFSLPFSDILFPYLQYIYGFFYVSIFILGVVGNLAVCYIISCR
LRQSATSIFLLNLSLADLKMALFCVPVTFFSDCIFMRWIFGRAMCHVFPF
VQALSVFLSSVTHTAISVDRYFVVFHPLRRQNFPIKGAVFVVSCIWIFSI
SISFPLIFVTEYKTINESDFCSEKWPTENNEMLYSLFVMVLQYFLPIIVI
IMTYSAIAIRLWFYQTPGESIRSRDEVIATSKKKMIKMFIIVAIFYSLSQ
LPRHIIYLTSKFSVSTSQNPFWDSTTVTILNFAHLLSMSACFYNPILYVW
LNSSFRKTLTNMLTCNKSSSLPPTSPKCISAFPDGYSSKKRMLSISSNNA
LFNAKLHERRFL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004983neuropeptide Y receptor activity
GO:0004930G-protein coupled receptor activity
GO:0045028G-protein coupled purinergic nucleotide receptor activity
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
GO:0007218neuropeptide signaling pathway
GO:0007186G-protein coupled receptor signaling pathway
GO:0007596blood coagulation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR005394P2Y12_rcpt
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR005394P2Y12 purinoceptorPRINTSPR01569P2Y12PRNCPTRcoord: 218..246
score: 35.34
coord: 305..324
score: 38.75
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 137..158
score: 24.98
coord: 56..77
score: 33.52
coord: 280..306
score: 28.99
coord: 185..208
score: 22.64
coord: 235..259
score: 18.89
coord: 102..124
score: 31.08
coord: 24..48
score: 26.01
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 39..298
e-value: 4.4E-42
score: 144.2
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 5..333
e-value: 1.9E-76
score: 258.8
NoneNo IPR availablePANTHERPTHR24235FAMILY NOT NAMEDcoord: 18..318
NoneNo IPR availableCDDcd153927tmA_PR4-likecoord: 24..306
e-value: 4.91605E-79
score: 241.881
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 4..328
NoneNo IPR availableTMHMMTMhelixcoord: 138..160
NoneNo IPR availableTMHMMTMhelixcoord: 279..301
NoneNo IPR availableTMHMMTMhelixcoord: 235..257
NoneNo IPR availableTMHMMTMhelixcoord: 95..117
NoneNo IPR availableTMHMMTMhelixcoord: 23..45
NoneNo IPR availableTMHMMTMhelixcoord: 192..214
NoneNo IPR availableTMHMMTMhelixcoord: 58..80
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 39..298
score: 37.162