Mitogen-activated protein kinase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30004871 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK13 (mitogen-activated protein kinase 13 [Source:HGNC Symbol;Acc:HGNC:6875]) HSP 1 Score: 170.629 bits (431), Expect = 4.702e-49 Identity = 110/355 (30.99%), Postives = 187/355 (52.68%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVI---FSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEED 1085
K YV+ TH+ +G +G V + + E VA+KK++ K YRE+ +L + + I L+D+++ ++ ++ + LV+P+M+ DL ++ FS+E +I +VYQ++ GLKY++ G++HRD+KP N+ +N++ ++KILDFGLAR ++T YVVTRWYR E+ + Y VD+WSVGCI E+ T + LFK D +D + +IL + G P ++ ++++ S+ P + R KD + A+P + AD L+++ML+L+ R+T A P F E + E+ +Q D+ L++ L D
Sbjct: 23 KTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGMEFSEE------KIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDK---AAKSYIQSLPQTPR------KDFTQLF---PRASPQA-AD-----------------LLEKMLELDVDKRLTAAQALTHPFF-----EPFRDPEEETEAQQPFDDSLEHEKLTVD 336
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK12 (mitogen-activated protein kinase 12 [Source:HGNC Symbol;Acc:HGNC:6874]) HSP 1 Score: 164.081 bits (414), Expect = 1.500e-46 Identity = 115/359 (32.03%), Postives = 184/359 (51.25%), Query Frame = 3
Query: 42 YVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYS-EITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLK-HKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKKIMKK 1109
Y + + +G +G V + T VA+KK+ K YRE+ +L + + I L+D+++ + T + LV+P+M DL ++ K L +I +VYQ++ GL+Y++ GIIHRD+KP N+ +N++ ++KILDFGLAR ++T YVVTRWYR E+ YT VD+WSVGCI E+ T + LFK +D +D +K I+ + G P E V L S +EA N + +EK ++L+ +A+P L + L+++ML L+ R+T A P F H E ++P+ ++ D+ D+VD D K++ K
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM--KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTP--------PAEFVQRLQS--DEAKNYMKGLPELEKKDFASILT--NASP------------------LAVNLLEKMLVLDAEQRVTAGEALAHPYFESLHDTE-----DEPQVQKY--DDSFDDVDRTLDEWKRVTYK 346
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK11 (mitogen-activated protein kinase 11 [Source:HGNC Symbol;Acc:HGNC:6873]) HSP 1 Score: 160.229 bits (404), Expect = 4.923e-45 Identity = 84/226 (37.17%), Postives = 133/226 (58.85%), Query Frame = 3
Query: 60 IRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEE 731
+ +G +G V + + VAVKK++ + + YRE+ +L + + I L+D+++ T+ + E+ LV M DL +++ + + Q + VYQL+ GLKY++ GIIHRD+KPSN+ +N++ +++ILDFGLAR +++T YV TRWYR EI Y VD+WSVGCI EL + LF +D +D +KRI+ ++G P VL +S E
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFL--VYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSE 253
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK11 (mitogen-activated protein kinase 11 [Source:HGNC Symbol;Acc:HGNC:6873]) HSP 1 Score: 160.229 bits (404), Expect = 4.923e-45 Identity = 84/226 (37.17%), Postives = 133/226 (58.85%), Query Frame = 3
Query: 60 IRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEE 731
+ +G +G V + + VAVKK++ + + YRE+ +L + + I L+D+++ T+ + E+ LV M DL +++ + + Q + VYQL+ GLKY++ GIIHRD+KPSN+ +N++ +++ILDFGLAR +++T YV TRWYR EI Y VD+WSVGCI EL + LF +D +D +KRI+ ++G P VL +S E
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFL--VYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSE 253
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK14 (mitogen-activated protein kinase 14 [Source:HGNC Symbol;Acc:HGNC:6876]) HSP 1 Score: 158.688 bits (400), Expect = 1.795e-44 Identity = 113/350 (32.29%), Postives = 173/350 (49.43%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE----LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDP-----ECSQFLCDE 1055
++Y N + + +G +G V + T VAVKK++ + K YRE+ +L + + I L+D++ T +SLE + LV M DL +++ ++ Q + +YQ++ GLKY++ IIHRD+KPSN+ +N++ ++KILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL T LF D +D +K IL ++G P +L+ +S E S RN + ++ K +FA N+ I L + L+++ML L+ RIT A F ++ + DP E L DE
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVF---TPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFL--IYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSE------SARNYIQSLTQMPKM------------------NFA------NVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDE 336
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: pmk-1 (Mitogen-activated protein kinase pmk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q17446]) HSP 1 Score: 167.933 bits (424), Expect = 2.856e-48 Identity = 108/307 (35.18%), Postives = 160/307 (52.12%), Query Frame = 3
Query: 42 YVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE-LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRIT 956
Y+N T I G +G V + + VA+KK N + + YRE+ +L + + I L+D+++ N +E + V M DL +++ + N Q + VYQ++ GLKY++ IIHRD+KPSNI +N++ ++KILDFGLAR ++T YV TRWYR EI YT VD+WSVGCI EL T + LF +D +D + RI+S+ G PD+ L+ +S E+ N RN L K +D KR ATP + + L+++ML L+P R T
Sbjct: 35 YINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILKIQRLNDDHIQFL--VYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEAR--NYIRN-------LPKMTRRDFKRLFAQ---ATPQA------------------IDLLEKMLHLDPDRRPT 309
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: pmk-2 (Mitogen-activated protein kinase pmk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MXI4]) HSP 1 Score: 154.836 bits (390), Expect = 3.251e-43 Identity = 88/245 (35.92%), Postives = 134/245 (54.69%), Query Frame = 3
Query: 42 YVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE-LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAP 770
Y + + G +G V + T + VA+KK K YRE+ +L + + ++D+++ + SL + V M DL +++ K L QI ++YQ++ GLKY++ GIIHRD+KPSNI +N+ +VKILDFGLAR ++T YV TRWYR EI YT VD+WSVGCI EL + PLF +D +D + +I+S++G P + + E+ N +N +P
Sbjct: 49 YNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIM--KIQRLTDEQIQLLIYQVLRGLKYIHSAGIIHRDLKPSNIAVNERCEVKILDFGLARAQDAEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEAR--NYIKNRSP 289
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: pmk-2 (Mitogen-activated protein kinase pmk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MXI4]) HSP 1 Score: 155.221 bits (391), Expect = 3.277e-43 Identity = 88/245 (35.92%), Postives = 134/245 (54.69%), Query Frame = 3
Query: 42 YVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE-LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAP 770
Y + + G +G V + T + VA+KK K YRE+ +L + + ++D+++ + SL + V M DL +++ K L QI ++YQ++ GLKY++ GIIHRD+KPSNI +N+ +VKILDFGLAR ++T YV TRWYR EI YT VD+WSVGCI EL + PLF +D +D + +I+S++G P + + E+ N +N +P
Sbjct: 49 YNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIM--KIQRLTDEQIQLLIYQVLRGLKYIHSAGIIHRDLKPSNIAVNERCEVKILDFGLARAQDAEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEAR--NYIKNRSP 289
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: kgb-1 (GLH-binding kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:O44408]) HSP 1 Score: 147.517 bits (371), Expect = 1.857e-40 Identity = 84/237 (35.44%), Postives = 132/237 (55.70%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRL-YQIIKI-VYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLAR----DMKDDLTKYVVTRWYRPLEIFYTSSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSE 728
+YVN + + G G V +++T + VA+KK+ + K YRE +L I I L++ ++ T+ + E+ LV+ M ++L VI + LRL ++ + VYQ + +K+L+ G+IHRD+KPSNI +N +K+LDFGLAR D ++ YVVTR+YR E+ Y+ VD+WSVGCI E+ LF D +D +I S++G PDDH + + +
Sbjct: 37 RYVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVI----HRLRLDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDYVVTRYYRAPEVILGLPYSEKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLGQ 269
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: cdk-7 (Cyclin-dependent kinase 7 [Source:UniProtKB/Swiss-Prot;Acc:G5EFV5]) HSP 1 Score: 142.895 bits (359), Expect = 2.308e-39 Identity = 84/238 (35.29%), Postives = 129/238 (54.20%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISL---CQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLAR---DMKDDLTKYVVTRWYRPLEIFYTS-SYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSE 728
++Y H+ G F V+ Q++ + E VA+KKI + + +T REI +L +I+ I L D+ G + LV +M+ DL HVI KE L I I Q+++GL++L+ I+HRD+KP+N+ +NK VK+ DFGLAR + T VVTRWYR E+ + + SY +D+WSVGCI EL + P+F +D + +I +I+G P ++E
Sbjct: 3 RRYDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHHDNIIGLRDVI-----GHRTSIQLVFDFMDTDLEHVIKDKEIILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPNRNYTHQVVTRWYRAPELLFGARSYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTE 235
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38a (gene:FBgn0015765 transcript:FBtr0084580) HSP 1 Score: 160.999 bits (406), Expect = 1.078e-45 Identity = 97/283 (34.28%), Postives = 152/283 (53.71%), Query Frame = 3
Query: 42 YVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE----LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGL-------------NSFRNEAPNSCR-LEKHIEKDVKRTLLSDE 833
Y + + +G +G+V K TN VA+KK+ K YRE+ +L ++ + I L+DI+ SLE + LV M+ DL ++I + +L + +VYQ++ GLKY++ G+IHRD+KPSNI +N++ +++ILDFGLAR ++++T YV TRWYR EI Y VD+WSVGCI EL T+ LF D + + I+ ++G P L+ +S E N F+N P + LEK +E D ++ + ++E
Sbjct: 25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNII--RMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEE 305
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38a (gene:FBgn0015765 transcript:FBtr0300572) HSP 1 Score: 160.999 bits (406), Expect = 1.078e-45 Identity = 97/283 (34.28%), Postives = 152/283 (53.71%), Query Frame = 3
Query: 42 YVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE----LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGL-------------NSFRNEAPNSCR-LEKHIEKDVKRTLLSDE 833
Y + + +G +G+V K TN VA+KK+ K YRE+ +L ++ + I L+DI+ SLE + LV M+ DL ++I + +L + +VYQ++ GLKY++ G+IHRD+KPSNI +N++ +++ILDFGLAR ++++T YV TRWYR EI Y VD+WSVGCI EL T+ LF D + + I+ ++G P L+ +S E N F+N P + LEK +E D ++ + ++E
Sbjct: 25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNII--RMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEE 305
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38a (gene:FBgn0015765 transcript:FBtr0084581) HSP 1 Score: 160.999 bits (406), Expect = 1.078e-45 Identity = 97/283 (34.28%), Postives = 152/283 (53.71%), Query Frame = 3
Query: 42 YVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE----LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGL-------------NSFRNEAPNSCR-LEKHIEKDVKRTLLSDE 833
Y + + +G +G+V K TN VA+KK+ K YRE+ +L ++ + I L+DI+ SLE + LV M+ DL ++I + +L + +VYQ++ GLKY++ G+IHRD+KPSNI +N++ +++ILDFGLAR ++++T YV TRWYR EI Y VD+WSVGCI EL T+ LF D + + I+ ++G P L+ +S E N F+N P + LEK +E D ++ + ++E
Sbjct: 25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNII--RMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEE 305
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38b (gene:FBgn0024846 transcript:FBtr0080534) HSP 1 Score: 155.992 bits (393), Expect = 9.738e-44 Identity = 92/283 (32.51%), Postives = 148/283 (52.30%), Query Frame = 3
Query: 42 YVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL----ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDV-------------NGLNSFRNEAPNSCR-LEKHIEKDVKRTLLSDE 833
Y N + G +G+V K T+ VA+KK+ K YRE+ +L ++ + I L+D++ SL ++ +V M+ DL ++I +++ + Q + VYQ++ GLKY++ G+IHRD+KPSNI +N++ +++ILDFGLAR + ++T YV TRWYR EI Y D+WSVGCI EL T LF D + + I+ ++G P D + +S E N + FR P + LEK +E D + + +++
Sbjct: 24 YQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFL--VYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQ 304
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: rl (gene:FBgn0003256 transcript:FBtr0113703) HSP 1 Score: 149.443 bits (376), Expect = 3.666e-41 Identity = 108/324 (33.33%), Postives = 161/324 (49.69%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLAR--DMKDD----LTKYVVTRWYRPLEIFYTS-SYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEG-VSEEDVNGLNS--FRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSP 980
+Y+ +I G +G V + LTN+ VA+KKI+ Q ++T+ REI IL + + I + DI + + ++ +V ME DL+ ++ K L I +YQ++ GLKY++ ++HRD+KPSN+ +NK D+KI DFGLAR D + D LT+YV TRWYR EI S YT ++D+WSVGCI E+ + P+F +D + IL ++G P LE ++E+ N L S F+ P + L + DA L L L+ +ML NP RI A P
Sbjct: 37 RYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISPFEHQTYCQRTL-REITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLL--KTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLPFKPNVPWA-------------KLFPNADA--------------------LALDLLGKMLTFNPHKRIPVEEALAHP 324
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk11 (mitogen-activated protein kinase 11 [Source:ZFIN;Acc:ZDB-GENE-040625-75]) HSP 1 Score: 164.081 bits (414), Expect = 1.057e-46 Identity = 87/234 (37.18%), Postives = 139/234 (59.40%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEE 731
++Y N T + +G +G V ++ + VAVKK++ + + YRE+ +L + + I L+D+++ + + E+ LV M DL +++ K L + ++YQL+ GLKY++ G+IHRD+KPSN+ +N++ +++ILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL + LF ND +D +KRI+ ++G P VL+ +S E
Sbjct: 21 ERYQNLTPVGSGAYGSVCSAYDVRLRQKVAVKKLSRPFQSLIHSRRTYRELRLLKHMKHENVIGLLDVFTPAASLEEFNEVYLVTNLMGADLNNIV--KFQRLSDEHVQFLIYQLLRGLKYIHSAGLIHRDLKPSNVAVNEDCELRILDFGLARQTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMGELLKGKVLFPGNDYIDQLKRIMEVVGTPTPDVLKKISSE 252
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk12a (mitogen-activated protein kinase 12a [Source:NCBI gene;Acc:30681]) HSP 1 Score: 162.155 bits (409), Expect = 4.578e-46 Identity = 105/318 (33.02%), Postives = 163/318 (51.26%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIY-SEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIF 986
+Y + + G +G V + T VA+KK++ K YRE+ +L + I L+D++ ++++ + + LV+P+M DL ++ K L ++ +VYQ++ GLKY++ GIIHRD+KP N+ IN+ ++KILDFGLAR ++T YVVTRWYR E+ + YT VD+WSVGCI E+ +PLFK +D +D + I+ + G P + ED RN R K KD+ R LL N++ + +K++ ML L+P +RIT A P F
Sbjct: 24 RYKDLKQVGTGAYGTVCYALDRRTGAKVAIKKLHRPFQSDLFAKRAYRELRLLKHMKHDNVIGLVDVFTADLSLDRFHDFYLVMPFMGTDLGKLM--KMERLSEERVQYLVYQMLKGLKYIHAAGIIHRDLKPGNLAINEECELKILDFGLARQTDSEMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLLGKPLFKGHDHLDQLMEIMKVTGTPSKEFTAKLQSEDA------RNYVTKLPRFRK---KDL-RILLP----------------NVNPQ----AIKVLDGMLLLDPESRITAAEALAFPFF 309
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: zgc:171775 (zgc:171775 [Source:ZFIN;Acc:ZDB-GENE-030131-4309]) HSP 1 Score: 162.155 bits (409), Expect = 4.989e-46 Identity = 88/240 (36.67%), Postives = 140/240 (58.33%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE----LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYR-PLEIFYTSSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNG 743
+Y + + +G +G V + T E VA+KK+ + K YRE+ +L I I L++++ T SLE +V+P++ DL H++ K+ + I + YQ++ GLKY++ GIIHRD+KP+N+ +++N ++KILDFGLAR + ++T YVVTRWYR P IF YT VD+WS GCI E+ T E LF +D +D +K+IL++ G P+ ++ + +D
Sbjct: 24 RYTSLKPVGSGAYGTVCFAVDQKTKEKVAIKKLYRPFQSLIHAKRAYRELRLLRHIQHDNVICLLNVF---TPDSSLEKFDTFYMVMPFVAQDLGHIMKRKQLTSNV--ITYLFYQILRGLKYIHSAGIIHRDLKPNNLAVDENCELKILDFGLARHTETEMTGYVVTRWYRAPEVIFNWMHYTQTVDVWSAGCILAEMITGEVLFPGSDSIDQLKKILNLTGTPNSTLVLKMQSKDAQS 258
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk14a (mitogen-activated protein kinase 14a [Source:NCBI gene;Acc:65237]) HSP 1 Score: 160.229 bits (404), Expect = 2.606e-45 Identity = 110/351 (31.34%), Postives = 172/351 (49.00%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPD-SFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEE 1082
+Y N + + +G +G V + T VAVKK++ + K YRE+ +L + + I L+D+++ T+ K ++ LV M DL +++ ++ Q + +YQ++ GLKY++ IIHRD+KPSN+ +N++ ++KILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL T LF D +D +K I+ ++G P +L +S E RT +S P +FAD + I + L+++ML L+ RIT A P F ++ ++PE F +D+EE
Sbjct: 24 QYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTYRELRLLKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFL--IYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNVTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMLLVGTPGPGLLMKISSESA-------------------------RTYISSLPQMPKRNFAD------VFIGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYH----DPDDEPEAEPFDQSFESRELDIEE 337
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk14a (mitogen-activated protein kinase 14a [Source:NCBI gene;Acc:65237]) HSP 1 Score: 160.229 bits (404), Expect = 2.606e-45 Identity = 110/351 (31.34%), Postives = 172/351 (49.00%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPD-SFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEE 1082
+Y N + + +G +G V + T VAVKK++ + K YRE+ +L + + I L+D+++ T+ K ++ LV M DL +++ ++ Q + +YQ++ GLKY++ IIHRD+KPSN+ +N++ ++KILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL T LF D +D +K I+ ++G P +L +S E RT +S P +FAD + I + L+++ML L+ RIT A P F ++ ++PE F +D+EE
Sbjct: 24 QYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTYRELRLLKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFL--IYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNVTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMLLVGTPGPGLLMKISSESA-------------------------RTYISSLPQMPKRNFAD------VFIGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYH----DPDDEPEAEPFDQSFESRELDIEE 337
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:100101766]) HSP 1 Score: 172.17 bits (435), Expect = 9.310e-50 Identity = 113/346 (32.66%), Postives = 174/346 (50.29%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKH-----KCEIVKYSEDPECSQFLCDE 1055
+Y T + +G FG V + T + VAVKK++ + + YRE+ +L + + I L+D+++ T+G++ E+ LV M DL +++ K L I ++YQL+ GLKY++ GIIHRD+KPSN+ +N++ +++ILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL + LF ND +D +KRI+ ++G P+ L +S E P ++D+K A P L + L+++ML L+ RIT A P F+++ + E Y E E + DE
Sbjct: 22 RYQRLTPVGSGAFGSVCSAYDTKTRQKVAVKKLSRPFQSLVHARRTYRELRLLKHMKHENVIGLLDVFTPSTSGENFNEVYLVTNLMGADLNNIV--KCQKLTDDHIQFLIYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLKGKALFPGNDYIDQLKRIMEVVGTPNSEFLLKISSEHARRYIESLPYMP---------QQDLKEVF---HGANP------------------LAIDLLEKMLILDSDKRITATEALAHPYFVQYHDPDDEPEAEPYDESTENKERTIDE 335
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:100101766]) HSP 1 Score: 172.17 bits (435), Expect = 1.716e-49 Identity = 92/236 (38.98%), Postives = 141/236 (59.75%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVN 740
+Y T + +G FG V + T + VAVKK++ + + YRE+ +L + + I L+D+++ T+G++ E+ LV M DL +++ K L I ++YQL+ GLKY++ GIIHRD+KPSN+ +N++ +++ILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL + LF ND +D +KRI+ ++G P+ L +S E V+
Sbjct: 24 RYQRLTPVGSGAFGSVCSAYDTKTRQKVAVKKLSRPFQSLVHARRTYRELRLLKHMKHENVIGLLDVFTPSTSGENFNEVYLVTNLMGADLNNIV--KCQKLTDDHIQFLIYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLKGKALFPGNDYIDQLKRIMEVVGTPNSEFLLKISSEHVS 257
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:100101766]) HSP 1 Score: 171.785 bits (434), Expect = 1.887e-49 Identity = 92/236 (38.98%), Postives = 141/236 (59.75%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVN 740
+Y T + +G FG V + T + VAVKK++ + + YRE+ +L + + I L+D+++ T+G++ E+ LV M DL +++ K L I ++YQL+ GLKY++ GIIHRD+KPSN+ +N++ +++ILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL + LF ND +D +KRI+ ++G P+ L +S E V+
Sbjct: 24 RYQRLTPVGSGAFGSVCSAYDTKTRQKVAVKKLSRPFQSLVHARRTYRELRLLKHMKHENVIGLLDVFTPSTSGENFNEVYLVTNLMGADLNNIV--KCQKLTDDHIQFLIYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLKGKALFPGNDYIDQLKRIMEVVGTPNSEFLLKISSEHVS 257
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:100101766]) HSP 1 Score: 171.785 bits (434), Expect = 2.108e-49 Identity = 92/236 (38.98%), Postives = 141/236 (59.75%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVN 740
+Y T + +G FG V + T + VAVKK++ + + YRE+ +L + + I L+D+++ T+G++ E+ LV M DL +++ K L I ++YQL+ GLKY++ GIIHRD+KPSN+ +N++ +++ILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL + LF ND +D +KRI+ ++G P+ L +S E V+
Sbjct: 22 RYQRLTPVGSGAFGSVCSAYDTKTRQKVAVKKLSRPFQSLVHARRTYRELRLLKHMKHENVIGLLDVFTPSTSGENFNEVYLVTNLMGADLNNIV--KCQKLTDDHIQFLIYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLKGKALFPGNDYIDQLKRIMEVVGTPNSEFLLKISSEHVS 255
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: ENSXETT00000036799.1 (mitogen-activated protein kinase 12 [Source:NCBI gene;Acc:100145045]) HSP 1 Score: 167.933 bits (424), Expect = 4.740e-48 Identity = 105/348 (30.17%), Postives = 181/348 (52.01%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE-LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYR-PLEIFYTSSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDL 1076
+Y + + +G +G V Q+ LT E VA+KK+ + K YRE+ +L + + I L+++++ + ++ + LV+P++ DL V+ + N I+ ++YQ++ GL+Y++ GI+HRD+KPSN+G+N++ ++KILDFGLAR + ++T YVVTRWYR P I Y VD+WSVGCI E+ T + LF D D + +I+ + G P + +N + S + A + ++ +K + L A +ET L+++MLDL+PGTR+ A P ++ DP+ + D+ +++DL
Sbjct: 24 RYRDLAAVGSGAYGTVCSAQDRLTGERVAIKKLLRPFQSLVHAKRAYRELRLLKHMKHENVISLLNVFTPDESMETFQTFYLVMPFIAVDLSRVMRMQRLNHS--TIVYLLYQILRGLQYIHAAGIVHRDLKPSNLGVNEDYELKILDFGLARPTEFEMTGYVVTRWYRAPEVILNWMHYNHTVDIWSVGCILAEMITGKVLFPGGDYFDELNKIIEVTGSPQPSL--------INKMES--SHAQDYVKMLPKKQKKNFKELFPTMSA---------------VET-----DLLEKMLDLDPGTRVNATEALAHPYLEEYN------DSDPDPTADKYDDSFESLDL 333
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk13 (mitogen-activated protein kinase 13 [Source:MGI Symbol;Acc:MGI:1346864]) HSP 1 Score: 169.088 bits (427), Expect = 1.509e-48 Identity = 114/366 (31.15%), Postives = 191/366 (52.19%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVI---FSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKK-IMKKIS 1115
K Y+ H+ +G +G V + T E VA+KK++ K YRE+ +L ++ + I L+D+++ ++ +S + LV+P+M+ DL ++ FS++ ++ +VYQ++ GLKY++ GI+HRD+KP N+ +N++ ++KILDFGLAR ++T YVVTRWYR E+ + Y VD+WSVGCI E+ T + LFK D +D + +IL + G P ++ + ++ S+ P S + KD + A+P + AD L+ +ML+L+ R+T A P F E + E+ +Q D+ L++ L D K+ I K+IS
Sbjct: 23 KTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHENVIGLLDVFTPASSLRSFHDFYLVMPFMQTDLQKIMGMEFSED------KVQYLVYQMLKGLKYIHSAGIVHRDLKPGNLAVNEDCELKILDFGLARHTDTEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLKDK---AAKSYIQSLPQSPK------KDFTQLF---PRASPQA-AD-----------------LLDKMLELDVDKRLTAAQALAHPFF-----EPFRDPEEETEAQQPFDDALEHEKLSVDEWKQHIYKEIS 347
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk12 (mitogen-activated protein kinase 12 [Source:MGI Symbol;Acc:MGI:1353438]) HSP 1 Score: 163.696 bits (413), Expect = 1.325e-46 Identity = 119/355 (33.52%), Postives = 183/355 (51.55%), Query Frame = 3
Query: 42 YVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE----LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSED-PECSQFLCDEHLDNVD--LEE 1082
Y + + +G +G V + T VA+KK+ K YRE+ +L + + I L+D++ T +SL+ LV+P+M DL ++ K L +I +VYQ++ GLKY++ G+IHRD+KP N+ +N++ ++KILDFGLAR ++T YVVTRWYR E+ YT VD+WSVGCI E+ T + LFK ND +D +K I+ I G P E V L S EA N +EK ++L+ +A+P + + L+++ML L+ R+T A P F E ++ +ED P+ ++ D+ D+VD LEE
Sbjct: 27 YQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVF---TPDESLDDFTDFYLVMPFMGTDLGKLM--KHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKITGTP--------PPEFVQKLQS--AEAKNYMEGLPELEKKDFASVLT--NASPQA------------------VNLLERMLVLDAEQRVTAAEALTHPYF-----ESLRDTEDEPKAQKY--DDSFDDVDRTLEE 339
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk11 (mitogen-activated protein kinase 11 [Source:MGI Symbol;Acc:MGI:1338024]) HSP 1 Score: 162.155 bits (409), Expect = 6.237e-46 Identity = 85/226 (37.61%), Postives = 133/226 (58.85%), Query Frame = 3
Query: 60 IRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEE 731
+ +G +G V + + VAVKK++ + + YRE+ +L + + I L+D+++ T+ + E+ LV M DL +++ + + Q + VYQL+ GLKY++ GIIHRD+KPSN+ +N++ +++ILDFGLAR +++T YV TRWYR EI Y VD+WSVGCI EL + LF ND +D +KRI+ ++G P VL +S E
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFL--VYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSE 253
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk14 (mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865]) HSP 1 Score: 157.918 bits (398), Expect = 1.619e-45 Identity = 89/237 (37.55%), Postives = 136/237 (57.38%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE----LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEE 731
++Y N + + +G +G V + T VAVKK++ + K YRE+ +L + + I L+D++ T +SLE + LV M DL +++ ++ Q + +YQ++ GLKY++ IIHRD+KPSN+ +N++ ++KILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL T LF D +D +K IL ++G P +L+ +S E
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVF---TPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFL--IYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSE 253
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk14 (mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865]) HSP 1 Score: 160.229 bits (404), Expect = 2.581e-45 Identity = 113/350 (32.29%), Postives = 173/350 (49.43%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE----LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDP-----ECSQFLCDE 1055
++Y N + + +G +G V + T VAVKK++ + K YRE+ +L + + I L+D++ T +SLE + LV M DL +++ ++ Q + +YQ++ GLKY++ IIHRD+KPSN+ +N++ ++KILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL T LF D +D +K IL ++G P +L+ +S E S RN + ++ K +FA N+ I L + L+++ML L+ RIT A F ++ + DP E L DE
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVF---TPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFL--IYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSE------SARNYIQSLAQMPKM------------------NFA------NVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDE 336
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|Q9WTY9|MK13_RAT (Mitogen-activated protein kinase 13 OS=Rattus norvegicus OX=10116 GN=Mapk13 PE=1 SV=1) HSP 1 Score: 172.17 bits (435), Expect = 5.448e-49 Identity = 113/366 (30.87%), Postives = 192/366 (52.46%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE-LCLVLPYMEYDLFHVI---FSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKK-IMKKIS 1115
K Y+ H+ +G +G V + T E VA+KK++ K YRE+ +L ++ + I L+D+Y+ T+ ++ + LV+P+M+ DL ++ FS+E ++ +VYQ++ GLKY++ GI+HRD+KP N+ +N++ ++KILDFGLAR ++T YVVTRWYR E+ + Y VD+WSVGCI E+ T + LFK D +D + +IL + G P ++ + ++ S+ P S + KD + A+P + + L+ +ML+L+ R+T A P+F E ++ E+ +Q D+ L+ +L D K+ I K+I+
Sbjct: 23 KTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHENVIGLLDVYTPATSVRNFQDFYLVMPFMQTDLQKIMGMEFSEE------KVQYLVYQMLKGLKYIHSAGIVHRDLKPGNLAVNEDCELKILDFGLARHTDAEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLKDK---AAKSYIQSLPQSPK------KDFTQLF---PRASPQA------------------VDLLDKMLELDVDKRLTAAQALAHPLF-----EPLRDPEEETEAQQPFDDALERENLSVDEWKQHIYKEIA 347
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|O15264|MK13_HUMAN (Mitogen-activated protein kinase 13 OS=Homo sapiens OX=9606 GN=MAPK13 PE=1 SV=1) HSP 1 Score: 170.629 bits (431), Expect = 2.258e-48 Identity = 110/355 (30.99%), Postives = 187/355 (52.68%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVI---FSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEED 1085
K YV+ TH+ +G +G V + + E VA+KK++ K YRE+ +L + + I L+D+++ ++ ++ + LV+P+M+ DL ++ FS+E +I +VYQ++ GLKY++ G++HRD+KP N+ +N++ ++KILDFGLAR ++T YVVTRWYR E+ + Y VD+WSVGCI E+ T + LFK D +D + +IL + G P ++ ++++ S+ P + R KD + A+P + AD L+++ML+L+ R+T A P F E + E+ +Q D+ L++ L D
Sbjct: 23 KTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGMEFSEE------KIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDK---AAKSYIQSLPQTPR------KDFTQLF---PRASPQA-AD-----------------LLEKMLELDVDKRLTAAQALTHPFF-----EPFRDPEEETEAQQPFDDSLEHEKLTVD 336
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|Q3T0N5|MK13_BOVIN (Mitogen-activated protein kinase 13 OS=Bos taurus OX=9913 GN=MAPK13 PE=2 SV=1) HSP 1 Score: 169.088 bits (427), Expect = 9.909e-48 Identity = 103/322 (31.99%), Postives = 173/322 (53.73%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVI---FSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIF 986
K YV+ THI +G +G V + + E VA+KK++ K YRE+ +L + + I L+D+++ ++ ++ + LV+P+M+ DL ++ FS++ +I +VYQ++ GLKY++ G++HRD+KP N+ +N++ ++KILDFGLAR ++T YVVTRWYR E+ + Y VD+WSVGCI E+ T + LFK D +D + +IL + G P ++ ++++ S+ P S + KD S+L S + T L+++ML+L+ R+T A P F
Sbjct: 23 KTYVSLTHIGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGMEFSED------KIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHTDVEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLNDK---AAKSYIQSLPQSPK------KDF-----------------SQLFPRASPQAT----DLLEKMLELDVDKRLTASQALAHPFF 308
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|Q9Z1B7|MK13_MOUSE (Mitogen-activated protein kinase 13 OS=Mus musculus OX=10090 GN=Mapk13 PE=1 SV=2) HSP 1 Score: 169.088 bits (427), Expect = 1.056e-47 Identity = 114/366 (31.15%), Postives = 191/366 (52.19%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVI---FSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKK-IMKKIS 1115
K Y+ H+ +G +G V + T E VA+KK++ K YRE+ +L ++ + I L+D+++ ++ +S + LV+P+M+ DL ++ FS++ ++ +VYQ++ GLKY++ GI+HRD+KP N+ +N++ ++KILDFGLAR ++T YVVTRWYR E+ + Y VD+WSVGCI E+ T + LFK D +D + +IL + G P ++ + ++ S+ P S + KD + A+P + AD L+ +ML+L+ R+T A P F E + E+ +Q D+ L++ L D K+ I K+IS
Sbjct: 23 KTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHENVIGLLDVFTPASSLRSFHDFYLVMPFMQTDLQKIMGMEFSED------KVQYLVYQMLKGLKYIHSAGIVHRDLKPGNLAVNEDCELKILDFGLARHTDTEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLKDK---AAKSYIQSLPQSPK------KDFTQLF---PRASPQA-AD-----------------LLDKMLELDVDKRLTAAQALAHPFF-----EPFRDPEEETEAQQPFDDALEHEKLSVDEWKQHIYKEIS 347
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|Q17446|PMK1_CAEEL (Mitogen-activated protein kinase pmk-1 OS=Caenorhabditis elegans OX=6239 GN=pmk-1 PE=1 SV=1) HSP 1 Score: 167.933 bits (424), Expect = 3.633e-47 Identity = 108/307 (35.18%), Postives = 160/307 (52.12%), Query Frame = 3
Query: 42 YVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE-LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRIT 956
Y+N T I G +G V + + VA+KK N + + YRE+ +L + + I L+D+++ N +E + V M DL +++ + N Q + VYQ++ GLKY++ IIHRD+KPSNI +N++ ++KILDFGLAR ++T YV TRWYR EI YT VD+WSVGCI EL T + LF +D +D + RI+S+ G PD+ L+ +S E+ N RN L K +D KR ATP + + L+++ML L+P R T
Sbjct: 35 YINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILKIQRLNDDHIQFL--VYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEAR--NYIRN-------LPKMTRRDFKRLFAQ---ATPQA------------------IDLLEKMLHLDPDRRPT 309
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A2P1E2H5 (Mitogen-activated protein kinase OS=Anadara broughtonii OX=148819 PE=2 SV=1) HSP 1 Score: 184.882 bits (468), Expect = 1.839e-51 Identity = 108/322 (33.54%), Postives = 178/322 (55.28%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKH 995
+KY T + +G +G V + +N VA+KK++ K YREI +L +N + I L+D+++ T + ++ LV P M D+ +++ +++ + Q + VYQ++ GLKY++ GIIHRD+KPSNI +N++ ++KILDFGLAR +D++T YV TRWYR EI Y VD+WSVGCI E+ T PLF+ ND +D + ++LS++G P+ +L+ ++ ++ S L K +K+ K + A P + + L+++MLDL+P TRIT + A P +++
Sbjct: 23 QKYQLLTAVGSGAYGLVCSAVDTTSNAKVAIKKLSRPFQSPIHAKRTYREIRMLKHMNHENIIGLLDVFTPTTTYEEFNDVYLVAPLMGADMSNILKTQKLSDDHVQFL--VYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELKILDFGLARHTEDEMTGYVATRWYRAPEIVLNWMHYGQTVDIWSVGCIMAEMLTNRPLFQGNDHIDQLNKVLSLVGNPNQKLLDKINSKEARDYVS---------SLPKFGKKEFKEVFIG---ANPKA------------------VDLLERMLDLDPDTRITAVEALAHPYLMQY 312
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A3P9KJQ5 (Mitogen-activated protein kinase OS=Oryzias latipes OX=8090 PE=4 SV=1) HSP 1 Score: 182.57 bits (462), Expect = 1.540e-50 Identity = 121/357 (33.89%), Postives = 185/357 (51.82%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIY-SEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEG-VSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKK 1097
++Y + + +G +G V + T VA+KK+ K YRE+ +L + + I L+D++ ++++ + L+ LV+P+M DL ++ K + L +I +VYQ++ GLKY++ GIIHRD+KP N+GIN++ ++KILDFGLAR ++T YVVTRWYR E+ + YT VD+WSVGCI E+ +PLFK ND +D + I+ I G P L VSEE L S L K +KD+++ T D A S ++++ML L+P R+T A P F E+ E+ E + D LDN +L D K+
Sbjct: 23 ERYRDLKQVGSGAYGTVCSATDSRTGAKVAIKKLYRPFQSEIFAKRAYRELRLLKHMKHENVIGLLDVFTADLSLDRFLDFYLVMPFMGTDLGKLM--KMHKLSEDKIQYLVYQMLKGLKYIHSAGIIHRDLKPGNLGINQDCELKILDFGLARQTDSEMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLQGKPLFKGNDHLDQLTEIMKITGTPSPEFLSKLVSEEAKKYLKS----------LPKQEKKDLQKVF-----PTSDVHAVS----------------MMEKMLLLDPEKRVTAAEALTLPYF----TELRDSEEEKEAQPY--DHSLDNAELSVDQWKR 340
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A3P9JV02 (Mitogen-activated protein kinase OS=Oryzias latipes OX=8090 PE=4 SV=1) HSP 1 Score: 181.8 bits (460), Expect = 3.835e-50 Identity = 121/356 (33.99%), Postives = 183/356 (51.40%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIY-SEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEG-VSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKK 1097
+Y + + +G +G V + T VA+KK+ K YRE+ +L + + I L+D++ ++++ + L+ LV+P+M DL ++ K + L +I +VYQ++ GLKY++ GIIHRD+KP N+GIN++ ++KILDFGLAR ++T YVVTRWYR E+ + YT VD+WSVGCI E+ +PLFK ND +D + I+ I G P L VSEE L S L K +KD+++ T D A S ++++ML L+P R+T A P F E E+ E + D LDN +L D K+
Sbjct: 24 RYRDLKQVGSGAYGTVCSATDSRTGAKVAIKKLYRPFQSEIFAKRAYRELRLLKHMKHENVIGLLDVFTADLSLDRFLDFYLVMPFMGTDLGKLM--KMHKLSEDKIQYLVYQMLKGLKYIHSAGIIHRDLKPGNLGINQDCELKILDFGLARQTDSEMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLQGKPLFKGNDHLDQLTEIMKITGTPSPEFLSKLVSEEAKKYLKS----------LPKQEKKDLQKVF-----PTSDVHAVS----------------MMEKMLLLDPEKRVTAAEALTLPYF----TEFRDSEEEKEAQPY--DHSLDNAELSVDQWKR 340
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A1J0I8W7 (Mitogen-activated protein kinase OS=Crassostrea hongkongensis OX=298176 PE=2 SV=1) HSP 1 Score: 181.415 bits (459), Expect = 4.738e-50 Identity = 111/338 (32.84%), Postives = 174/338 (51.48%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQF 1043
++Y N + G +G+V + N VA+KK+ K YRE+ +L +N + I L+D+++ T ++ LV P M DL ++I K L + +VYQ++ GLKY++ GIIHRD+KPSNI +N++ ++KILDFGLAR +D +T YV TRWYR EI Y+ VD+WSVGCI E+ +PLF D +D + R+LS++G P+ +L+ ++ + RN + K +KD + L A P++ + L++QMLDL+ TRIT A P ++ + + +P F
Sbjct: 24 QRYQNLIPVGAGAYGQVCSAVDTQRNTKVAIKKLARPFQSAIHAKRTYRELRMLKHMNHENIIGLLDVFTATTTFDEFNDVYLVSPLMGADLNNII--KTQTLSDDHVQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELKILDFGLARHTEDSMTGYVATRWYRAPEIVLNWMHYSQTVDIWSVGCIMAEMLAGKPLFPGTDHIDQLTRVLSLVGTPNQALLDKINSPEA------RNYV---ASMPKWPKKDFREVFLG---ANPNA------------------INLMEQMLDLDADTRITATEALAHPYLAQYADPTDEPTAEPYDQSF 329
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: H2MNU8 (Mitogen-activated protein kinase OS=Oryzias latipes OX=8090 GN=LOC101159668 PE=4 SV=2) HSP 1 Score: 181.03 bits (458), Expect = 6.448e-50 Identity = 118/356 (33.15%), Postives = 182/356 (51.12%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIY-SEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEG-VSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKK 1097
+Y + + +G +G V + T VA+KK+ K YRE+ +L + + I L+D++ ++++ + L+ LV+P+M DL ++ K + L +I +VYQ++ GLKY++ GIIHRD+KP N+GIN++ ++KILDFGLAR ++T YVVTRWYR E+ + YT VD+WSVGCI E+ +PLFK ND +D + I+ I G P L VSEE L S L K +KD+++ S + + ++++ML L+P R+T A P F E E+ E + D LDN +L D K+
Sbjct: 24 RYRDLKQVGSGAYGTVCSATDSRTGAKVAIKKLYRPFQSEIFAKRAYRELRLLKHMKHENVIGLLDVFTADLSLDRFLDFYLVMPFMGTDLGKLM--KMHKLSEDKIQYLVYQMLKGLKYIHSAGIIHRDLKPGNLGINQDCELKILDFGLARQTDSEMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLQGKPLFKGNDHLDQLTEIMKITGTPSPEFLSKLVSEEAKKYLKS----------LPKQEKKDLQKVFPSSD---------------------VHAVSMMEKMLLLDPEKRVTAAEALTLPYF----TEFRDSEEEKEAQPY--DHSLDNAELSVDQWKR 340
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk12b (mitogen-activated protein kinase 12-like [Source:NCBI gene;Acc:103035956]) HSP 1 Score: 168.318 bits (425), Expect = 1.723e-48 Identity = 111/357 (31.09%), Postives = 184/357 (51.54%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIY-SEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFP-DDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKK 1097
++Y + + G +G V + VA+KK++ K YRE+ +L + + I L+D++ SEI+ + + LV+P+M DL ++ K L ++ +VYQ++ GLKY++ GIIHRD+KP N+ +N+N ++KILDFGLAR ++T YVVTRWYR E+ Y+ VD+WSVGCI E+ PLFK ND +D ++ I+ I G P D +L+ S++ N + S L K +KD+ ++I + + V+ +++ML L+P +R++ +A P+F + + + P D +DN DL + K+
Sbjct: 23 ERYRDLIQVGTGAYGTVSSAIDRKAGVRVAIKKLHRPFQSRLFAKRAYRELRLLKHMKHENVIGLLDVFTSEISLDRFQDFYLVMPFMGTDLGKLM--KMERLCEDRVQFLVYQMLRGLKYIHSAGIIHRDLKPGNLAVNQNCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMHYSQTVDIWSVGCIMAEMLLGRPLFKGNDHLDQLREIMKITGTPGQDFILKLQSQDAKNYIRS----------LPKVPKKDL---------------------HSIFFKASSEVVSAMERMLLLDPDSRVSAAVALELPMFSEFREPEEETEALP------YDHSMDNADLSLEQWKR 340
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: zgc:171775 (mitogen-activated protein kinase 12-like [Source:NCBI gene;Acc:103042110]) HSP 1 Score: 166.777 bits (421), Expect = 6.085e-48 Identity = 86/237 (36.29%), Postives = 142/237 (59.92%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE-LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLE-IFYTSSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNG 743
+Y + I +G +G V + T E VA+KK+ + K YRE+ +L I I L+++++ ++ ++ + LV+P++ DL H++ + + R+ I+ + YQL+ GLKY++ GIIHRD+KP+N+ +++N ++KILDFGLAR + ++T YVVTRWYR E IF YT VD+WS GCI E+ T + LF ND +D + IL + G P+ +++ + +D
Sbjct: 24 RYTSLNSIGSGAYGTVCSAIDQKTKEKVAIKKLYRPFQSLIHAKRAYRELRLLRHIQHDNVICLLNVFTPDSSLETFQTFYLVMPFVAQDLGHIMKKRRLSERV--IVYLFYQLLRGLKYIHSAGIIHRDLKPNNLAVDENCELKILDFGLARHAEMEMTGYVVTRWYRAPEVIFNWMHYTQTVDIWSAGCILAEMITGQVLFPGNDSMDQLNMILELTGTPNSSLVQKMQSKDARS 258
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:103035641]) HSP 1 Score: 163.31 bits (412), Expect = 1.756e-46 Identity = 87/234 (37.18%), Postives = 139/234 (59.40%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEE 731
++Y N T + +G +G V ++ + VAVKK++ + + YRE+ +L + + I L+D++S + + E+ LV M DL +++ K L + ++YQL+ GLKY++ G+IHRD+KPSN+ +N++ +++ILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL + LF ND +D +KRI+ ++G P +L+ +S E
Sbjct: 21 ERYQNLTPVGSGAYGSVCSAYDVRLRQKVAVKKLSRPFQSLIHSRRSYRELRLLKHMKHENVIGLLDVFSPAASLEEFNEVYLVTNLMGADLNNIV--KFQRLSDEHVQFLIYQLLRGLKYIHSAGLIHRDLKPSNVAVNEDCELRILDFGLARQTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMGELLKGKVLFPGNDYIDQLKRIMEVVGTPTPDLLKKISSE 252
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk14b (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:103028137]) HSP 1 Score: 159.073 bits (401), Expect = 5.331e-45 Identity = 108/352 (30.68%), Postives = 177/352 (50.28%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGV-SEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEE 1082
++Y N + + +G +G V ++ + +AVKK++ + K YRE+ +L + + I L+D+++ TN + ++ LV M DL +++ ++ Q + +YQ++ GLKY++ IIHRD+KPSN+ +N++ ++KILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL T LF D ++ +++I+ + G P ++ + S E N +NS H+ K +FAD + I L + L+++ML L+ RIT A P F ++ + DP F E +D+EE
Sbjct: 23 ERYQNLSPVGSGAYGSVCSAYDIQSGLKIAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATNLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFL--IYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNYINSL-----------PHMPK--------------RNFAD------VFIGANPLAVDLLEKMLVLDTDKRITASEALAHPYFAQYHDPDDEPEADPYDQSFESRE----LDIEE 337
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk12a (mitogen-activated protein kinase 12 [Source:NCBI gene;Acc:103040333]) HSP 1 Score: 157.918 bits (398), Expect = 1.983e-44 Identity = 83/237 (35.02%), Postives = 135/237 (56.96%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIY-SEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVN 740
++Y + + G +G V + T VA+KK++ K +RE+ +L + I L++++ ++++ + + LV+P+M DL ++ K L ++ +VYQ++ GLKY++ GIIHRD+KP N+ IN+ ++KILDFGLAR ++T YVVTRWYR E+ + YT VD+WSVGCI E+ +PLFK ND +D + I+ I G P + + +D
Sbjct: 23 ERYRDLRQVGTGAYGTVCYALDCRTGTKVAIKKLHRPFQSELFAKRAFRELRLLKHMKHDNVIGLLNVFTADLSLDRFQDFYLVMPFMGTDLGKLM--KMERLTEDRVQYLVYQMLRGLKYIHAAGIIHRDLKPGNLAINEECELKILDFGLARQADSEMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLMGKPLFKGNDHLDQLTEIMKITGTPTQEFISKLQSQDAK 257
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: mapk12a (mitogen-activated protein kinase 12a [Source:NCBI gene;Acc:30681]) HSP 1 Score: 167.162 bits (422), Expect = 1.414e-48 Identity = 109/350 (31.14%), Postives = 179/350 (51.14%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSE-ITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLE 1079
K+Y + +G +G V + +++T VAVKK+ K YRE+ +L + + I L+D+++ T + + LV+P+M DL ++ K ++ ++YQ++ GLKY++ GIIHRD+KP N+ +N++ ++KILDFGLAR ++T YVVTRWYR E+ YT VD+WSVGCI E+ T +PLF ND +D + IL + G P ++++ + E NEA + +EK T+ + N I+I+ L+++ML L+P R T A P F + + + + +P D+ + V+LE
Sbjct: 25 KRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIM--KHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKPLFPGNDHMDQLMLILKLTGTPPQYLVDRMDE----------NEAAKYIKTLPKMEKRRISTVFPNA-------------NPIAID-------LLEKMLALDPEQRPTASEALQHPFFSETREPLEETEAEP------YDQTFEGVELE 336
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: mapk14a (mitogen-activated protein kinase 14a [Source:NCBI gene;Acc:65237]) HSP 1 Score: 156.762 bits (395), Expect = 9.437e-45 Identity = 117/355 (32.96%), Postives = 179/355 (50.42%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE----LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSND----GVDHVKRILSIMGFPDDHVLEGV-SEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKH-----KCEIVKYSEDPECSQFLCDE 1055
++YVN T + +G +G V + + T VAVKK++ + K YRE+ +L + + I LMD++ T SLE L LV M DL +++ ++ Q + VYQ++ GLKY++ GIIHRD+KPSN+ +N++ ++KILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL T LF D ++ + +IL + G P ++++ + S+E N + S P + + +D K L A P LV+ L+++ML L+ RIT A V F ++ + E Y + E +F +E
Sbjct: 23 RRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVF---TPNSSLEEFDDLYLVTDLMGADLNNIVKCQKLTDDHVQFL--VYQILRGLKYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDRILSDINQLVKILQLTGTPPQYLIDRMQSKEARNYIQSL----PYTQK------RDFKDVFLG---ANP------------------LVVDLLERMLVLDTDQRITAAEALVHQYFAQYHDPDDEPEAEPYDQSFENQEFPVEE 341
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: mapk1 (mitogen-activated protein kinase 1 [Source:ZFIN;Acc:ZDB-GENE-030722-2]) HSP 1 Score: 137.502 bits (345), Expect = 1.944e-37 Identity = 85/233 (36.48%), Postives = 128/233 (54.94%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDD------LTKYVVTRWYRPLEIFYTS-SYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLE 716
+Y + ++I G +G V + + VA+KKI+ Q ++T+ REI IL + + I + DI T + ++ +V ME DL+ ++ K L I +YQ++ GLKY++ ++HRD+KPSN+ +N D+KI DFGLAR D LT+YV TRWYR EI S YT ++D+WSVGCI E+ + PLF +D + IL I+G P L+
Sbjct: 35 RYTSLSYIGEGAYGMVCAAFDNVKLVRVAIKKISPFEHQTYCQRTL-REIKILLRFKHENIIGINDILRASTIDQMKDVYIVQDLMETDLYKLL--KGQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPLFPGKHYLDQLNHILGILGSPSQEDLD 264
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000729.1 (pep scaffold:Pmarinus_7.0:GL477416:20288:37329:-1 gene:ENSPMAG00000000656.1 transcript:ENSPMAT00000000729.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 135.576 bits (340), Expect = 2.721e-36 Identity = 82/227 (36.12%), Postives = 127/227 (55.95%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE----LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDD--LTKYVVTRWYRPLEIFYTSSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFP 698
K+Y N I +G G V +++ N VA+KK++ K YRE+ ++ +N + I L +++ T KSLE + LV+ M+ +L VI + L ++ ++YQ++ G+K+L+ GIIHRD+KPSNI + + +KILDFGLAR + +T YVVTR+YR E+ YT VD+WSVGC+ E+ LF D +D +I+ +G P
Sbjct: 24 KRYQNLKPIGSGAQGIVCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVF---TPQKSLEEFQDVYLVMELMDANLCQVI---QMELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCVLGEMIRHRILFPGKDYIDQWNKIIEQLGTP 244
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741]) HSP 1 Score: 130.954 bits (328), Expect = 1.214e-35 Identity = 80/246 (32.52%), Postives = 131/246 (53.25%), Query Frame = 3
Query: 60 IRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMD-IYSEITNGKSLELCLVLPYMEYDLF-HVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKY---VVTRWYRPLEIFYTSSY-TFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSC 779
I G +G V+K ++ +T + VA+KKI + T REI +L ++N + L+D I+SE +L LV +++ DL ++ + + L + ++QL+ G+ + + +HRD+KP N+ IN + +K+ DFGLAR L Y VVT WYR EI Y + AVD+WS+GCI E+ T+ LF + +D + RI +G PD+ V +G+++ L ++ P C
Sbjct: 10 IGEGTYGVVYKARHKMTGDTVALKKIRLDTETEGVPSTAIREIALLRELNHPNIVRLLDVIHSET------KLYLVFEFLDQDLKKYMDNAPPLGISLPLVKSYMHQLLQGIAFCHAQRTLHRDLKPQNLLINADGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKYYSTAVDVWSLGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDETVWQGITQ-----LPDYKPSFPRWC 244
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: HOG1 (Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]) HSP 1 Score: 139.428 bits (350), Expect = 7.225e-38 Identity = 91/261 (34.87%), Postives = 132/261 (50.57%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGV-SEEDVNGLNSF--RNEAPNSCRLEKHIEKDV 809
+Y + + G FG V + LT++ VA+KKI K YRE+ +L + + I L DI+ ++ V DL ++ ++ + Q +YQ++ GLKY++ G+IHRD+KPSNI IN+N D+KI DFGLAR +T YV TR+YR EI T Y VD+WS GCI E+ +PLF D V I ++G P V+ + SE + + S R+ P S R K +E D
Sbjct: 22 RYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLE----DIYFVTELQGTDLHRLLQTRPLEKQFVQYF--LYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERF-KTVEPDA 275
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: CTK1 (Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]) HSP 1 Score: 133.265 bits (334), Expect = 3.810e-35 Identity = 75/222 (33.78%), Postives = 124/222 (55.86%), Query Frame = 3
Query: 42 YVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDM--KDDLTKYVVTRWYRPLEIFY-TSSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFP 698
Y+ + G +G+V+K +N T ++VA+KK+ + + T REI +L + + +I E + ++ Y + DL ++ +KE + Q + QL++G++YL+ I+HRD+K SNI I+ ++KI DFGLAR M + D T V+T WYRP E+ T++Y VDMW GC+ VELF K +F+ ++ ++ ++ I IMG P
Sbjct: 183 YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVE----SQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTP 400
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: SLT2 (Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]) HSP 1 Score: 130.183 bits (326), Expect = 3.661e-34 Identity = 83/253 (32.81%), Postives = 127/253 (50.20%), Query Frame = 3
Query: 21 NMSYDKKYVNFTHIRNGCFGRVFKTQ--NMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQ---YCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDD-------LTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVN 740
+ S DK++ I +G +G V + + VA+KK+ + K RE+ +L C+Y MDI +G L L ME D+ +I S + L YQ++ GLKY++ ++HRD+KP N+ +N + +KI DFGLAR ++ LT+YV TRWYR EI + YT A+D+WS GCI E +P+FK D V+ + +IL ++G P D L + ++V
Sbjct: 16 DFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVF-YPDGSINGLYLYEELMECDMHQIIKSGQ-PLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQ 266
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: SGV1 (Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]) HSP 1 Score: 127.487 bits (319), Expect = 1.113e-32 Identity = 83/236 (35.17%), Postives = 121/236 (51.27%), Query Frame = 3
Query: 69 GCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLM----DIYSEITNGKSLELC----LVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLAR---------------DMKDDLTKYVVTRWYRPLE-IFYTSSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDD 704
G FG V+K ++ T VA+KKI +S+ + T REI IL ++N + I L+ D +ITN S L ++LPYM DL V+ + NL + I ++ Q++ GL Y++ +HRDIK +NI I+ N +K+ DFGLAR T VVTRWYR E + YT AVD+W VGC+ E F K+P+ + +D I ++G P +
Sbjct: 69 GTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTE 304
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]) HSP 1 Score: 121.324 bits (303), Expect = 2.915e-32 Identity = 76/245 (31.02%), Postives = 129/245 (52.65%), Query Frame = 3
Query: 24 MSYDKKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMD-IYSEITNGKSLELCLVLPYMEYDLFHVIFSK-----EYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMK---DDLTKYVVTRWYRPLEIFYTS-SYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSE 728
MS ++ + NG + V+K N T VA+K++ + + T T REI ++ ++ + + L D I++E +L LV +M+ DL + S+ L L + +QL+ GL + ++ I+HRD+KP N+ INK +K+ DFGLAR + + VVT WYR ++ S +Y+ ++D+WS GCI E+ T +PLF + + +K I IMG P++ + V++
Sbjct: 1 MSSSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREISLMKELKHENIVRLYDVIHTEN------KLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTK 238
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO46881 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNM4]) HSP 1 Score: 155.221 bits (391), Expect = 1.003e-43 Identity = 111/357 (31.09%), Postives = 179/357 (50.14%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFK---TQNMLTNE----IVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE-LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATP-DSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDL 1076
+KY + I G +G+V T+ TN VA+KK++ K YRE+ +L + + I L+D+++ + + + + +V M DL ++ ++ + Q + VYQ++ GLKY++ G+IHRD+KPSNI +N++ ++KILDFGLAR ++T YV TRWYR EI Y VD+WSVGCI EL T + LF ND +D + +I+ ++G P D L+ + E S RN +I + + D TP D + + L + L+++ML+L+ RIT + A P + +++P CS F D+ D +L
Sbjct: 22 RKYQELSPIGTGAYGQVCSSTITEPDPTNPDGPNTVAIKKLSRPFQSTMHAKRTYRELKLLRHMRHENVISLLDVFTTASAFEHFQDVYMVTELMGSDLNGILRFQKLSDEHVQFL--VYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELKILDFGLARMTDAEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTSKTLFPGNDHIDQLTKIMQLVGKPSDDFLQKIDSE------SARN----------YIAQ------MPDYRKTPFDEYF---------VGANPLAVDLLEKMLNLDTDHRITAVEALSHPYLASY----ADPNDEPTCSTF--DDSFDEKEL 339
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO40573 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6R5]) HSP 1 Score: 153.295 bits (386), Expect = 5.677e-43 Identity = 116/373 (31.10%), Postives = 182/373 (48.79%), Query Frame = 3
Query: 33 DKKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLE-LCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLAR-------DMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNG-LNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDL-EEDLEKKIMKKISE 1118
D +Y I NG +G V + T VAVKKI+ + + T + +RE+ IL I + DI N + + +VL ME DL H I + L + +YQ++ GLKY++ ++HRD+KPSN+ +N+N ++KI DFG+AR + K +T+YV TRWYR E+ + + Y+ A+DMWSVGCI E+ + PLF + ++ ++ ILS+ G P + +E + E V LN ++ P EK K A P++ + L+ QML L+P RIT A P ++ E ++P C L D D V + +E L++ I+ +I +
Sbjct: 20 DARYKLIETIGNGAYGVVCSAMDTRTGAKVAVKKISRAFDVLTTARRTHRELKILRHFKHDNIICIRDILKPPVNLDEFDDVYVVLDLMESDL-HRIIHTDQPLTTEHVRYFLYQILRGLKYIHSAKVLHRDLKPSNLLVNENAELKIGDFGMARGLCSSPLEQKRFMTEYVATRWYRAPELMLSLNEYSEAIDMWSVGCILAEMIGRRPLFPGANYLNQLQMILSVTGTPSQNFIERMGAERVKTYLNQLPHKDP--VPFEKFFPK-----------AHPEA------------------INLLSQMLQLDPKERITVENALQHPFLKEYHSE----EDEPTCYSPL-DFKFDTVLMTKEALKEAIVNEIKD 355
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO37567 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFE6]) HSP 1 Score: 149.058 bits (375), Expect = 4.377e-42 Identity = 85/228 (37.28%), Postives = 132/228 (57.89%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTN-EIVAVKKINISLCQMQTKKTIYREICILCQINS---QYCIYLMDIYS-EITNGKSLELCLVLPYMEYDLF-HVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDD--LTKYVVTRWYRPLEIFYTSSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFP 698
KY I G +G V+K +++L + + VA+K++ I + + REI +L QI++ + L+DI+ + + L LV +++ DL ++ + + L ++I + YQ++ G+ +L+ I+HRDIKP NI + K+ VKI DFGLAR KD LT VVT WYR E+ SSY +VD+WSV CI ELF + PLF+ + VD + +I SI+G P
Sbjct: 4 KYEEVAEIGTGAYGTVYKAKDLLNDGKFVALKRVRIQNSEEGMPLSTIREIALLKQIDNFAHPNVVRLLDIFHIPMLTARETHLNLVFEHVDQDLAAYLEYCPQPGLGEWKIKDLTYQILNGVDFLHTHRIVHRDIKPQNILVTKDGQVKIADFGLARVYKDAMALTSVVVTLWYRAPEVLLQSSYATSVDIWSVACILAELFNRRPLFEGKNDVDQLDKIFSIIGSP 231
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO37435 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFQ0]) HSP 1 Score: 145.976 bits (367), Expect = 1.322e-40 Identity = 84/227 (37.00%), Postives = 126/227 (55.51%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDD------LTKYVVTRWYRPLEIFYTS-SYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFP 698
+Y N +I G +G V + T E +A+KKI+ Q ++T+ REI IL + + I ++DI ++ +V P ME D++ ++ K L I +YQ++ GLKY++ ++HRD+KPSN+ +N D+KI DFGLAR D LT+YV TRWYR EI S Y+ A+D+WSVGCI E+ PLF +D + IL+++G P
Sbjct: 20 RYTNLNYIGEGAYGMVVAGVDNTTGERIAIKKISPFEHQTYCQRTL-REIKILSRFKHENIIGILDIIRAPRAEDMKDIYIVQPLMETDMYKLL--KTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYSKAIDIWSVGCILAEMLANRPLFPGKHYLDQLNLILNVLGSP 243
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO41403 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4F0]) HSP 1 Score: 137.117 bits (344), Expect = 1.040e-37 Identity = 86/234 (36.75%), Postives = 123/234 (52.56%), Query Frame = 3
Query: 60 IRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEY-------NLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKY---VVTRWYRPLEIFYTSSY-TFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSE 728
I G +G V+K ++ T +VA+KKI + T REI +L ++N + L+D+ + N KSL LV ++ DL K+Y + I VYQL+ G+ Y + ++HRD+KP N+ I+KN +K+ DFGLAR + Y VVT WYR EI S Y VD+WS+GCI E+ T+ LF + +D + RI +G PDD V GVSE
Sbjct: 10 IGEGTYGVVYKARDKTTGRMVALKKIRLDTESEGVPSTAIREISLLKELNHPNVVSLLDV---VHNQKSL--YLVFEFLSQDL------KKYMDCLPPSGISTSLIKSYVYQLLSGVAYCHSHRVLHRDLKPQNLLIDKNGAIKLADFGLARAFGVPVRSYTHEVVTLWYRAPEILLGSRYYATPVDVWSIGCIFAEMKTRRALFPGDSEIDQLFRIFRTLGTPDDKVWPGVSE 232
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk12a (mitogen-activated protein kinase 12 [Source:NCBI gene;Acc:101159668]) HSP 1 Score: 181.03 bits (458), Expect = 2.427e-53 Identity = 118/356 (33.15%), Postives = 182/356 (51.12%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIY-SEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEG-VSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKK 1097
+Y + + +G +G V + T VA+KK+ K YRE+ +L + + I L+D++ ++++ + L+ LV+P+M DL ++ K + L +I +VYQ++ GLKY++ GIIHRD+KP N+GIN++ ++KILDFGLAR ++T YVVTRWYR E+ + YT VD+WSVGCI E+ +PLFK ND +D + I+ I G P L VSEE L S L K +KD+++ S + + ++++ML L+P R+T A P F E E+ E + D LDN +L D K+
Sbjct: 24 RYRDLKQVGSGAYGTVCSATDSRTGAKVAIKKLYRPFQSEIFAKRAYRELRLLKHMKHENVIGLLDVFTADLSLDRFLDFYLVMPFMGTDLGKLM--KMHKLSEDKIQYLVYQMLKGLKYIHSAGIIHRDLKPGNLGINQDCELKILDFGLARQTDSEMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLQGKPLFKGNDHLDQLTEIMKITGTPSPEFLSKLVSEEAKKYLKS----------LPKQEKKDLQKVFPSSD---------------------VHAVSMMEKMLLLDPEKRVTAAEALTLPYF----TEFRDSEEEKEAQPY--DHSLDNAELSVDQWKR 340
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk14b (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:101162042]) HSP 1 Score: 162.925 bits (411), Expect = 1.899e-46 Identity = 110/351 (31.34%), Postives = 180/351 (51.28%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDV-NGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLE 1079
++Y N + + +G +G V + ++ T VAVKK++ + K YRE+ +L + + I L+D+++ T+ ++ LV M DL +++ ++ Q + +YQ++ GLKY++ GI+HRD+KPSN+ +N++ ++KILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL T LF D +D +K I+ ++G P +L +S E N +NS H+ K +FAD + I L + L+++ML L+ RIT A P F ++ ++PE + D+ ++ +LE
Sbjct: 23 ERYQNLSPVGSGAYGSVCSSYDVKTCLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLDEFSDVYLVTHLMGADLNNIVKCQKLTDDHVQFL--IYQILRGLKYIHSAGIVHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMMLVGTPGPELLMKISSEPARNYINSL-----------PHMPK--------------RNFAD------VFIGANPLAVDLLEKMLVLDTDKRITASEALAHPYFAQYH----DPDDEPEAEPY--DQSFESRELE 334
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk12b (mitogen-activated protein kinase 12 [Source:NCBI gene;Acc:101154993]) HSP 1 Score: 161.77 bits (408), Expect = 6.243e-46 Identity = 89/243 (36.63%), Postives = 141/243 (58.02%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIY-SEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPD-DHVLEGVSEEDVNGLNSF 755
++Y + I G +G V + T VA+KK++ K YRE+ +L + + I L+D++ +EI+ + + LV+P+M DL ++ K L ++ +VYQ++ GLKY++ GI+HRD+KP N+ IN + ++KILDFGLAR ++T YVVTRWYR E+ YT VD+WS GCI E+ +PLFK +D +D ++ I+ I G P D V++ S++ N + S
Sbjct: 25 ERYRDLKQIGTGAYGTVCSAWDRRTGAQVAIKKLHRPFQSKLFAKRAYRELRLLKHMRHENVIGLLDVFTAEISLDRFRDFYLVMPFMGTDLGKLM--KMEKLTEDRVQFLVYQILKGLKYIHSAGIVHRDLKPGNLAINPDCELKILDFGLARQADAEMTGYVVTRWYRAPEVILNWMHYTQTVDIWSAGCIMAEMLLGKPLFKGSDHLDQLREIMKITGTPSPDFVVKLQSQDAKNYIRSL 265
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk14b (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:101162042]) HSP 1 Score: 159.073 bits (401), Expect = 7.033e-45 Identity = 107/351 (30.48%), Postives = 180/351 (51.28%), Query Frame = 3
Query: 36 KKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGV-SEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLE 1079
++Y N + + +G +G V + ++ T VAVKK++ + K YRE+ +L + + I L+D+++ T+ ++ LV M DL +++ ++ Q + +YQ++ GLKY++ GI+HRD+KPSN+ +N++ ++KILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL T LF D ++ +++I+ + G P ++ + S E N +NS H+ K +FAD + I L + L+++ML L+ RIT A P F ++ ++PE + D+ ++ +LE
Sbjct: 23 ERYQNLSPVGSGAYGSVCSSYDVKTCLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLDEFSDVYLVTHLMGADLNNIVKCQKLTDDHVQFL--IYQILRGLKYIHSAGIVHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNYINSL-----------PHMPK--------------RNFAD------VFIGANPLAVDLLEKMLVLDTDKRITASEALAHPYFAQYH----DPDDEPEAEPY--DQSFESRELE 334
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk14a (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:101160731]) HSP 1 Score: 156.762 bits (395), Expect = 4.881e-44 Identity = 106/348 (30.46%), Postives = 174/348 (50.00%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDL 1076
+Y N + + +G +G V + T VAVKK++ + K YRE+ +L + + I L+D+++ T+ K ++ V M DL +++ ++ Q + +YQ++ GLKY++ IIHRD+KPSN+ +N++ ++KILDFGLAR D++T YV TRWYR EI Y VD+WSVGCI EL T LF D +D +K I+ ++G P +L +S E ++ + P+ + +FAD + I L + L+++ML L+ RIT A P F ++ ++PE + D+ ++ DL
Sbjct: 24 RYQNLSPVGSGAYGSVCSAYDTKTGLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLKEFTDVYFVNHLMGADLNNIVKCQKLTDDHVQFL--IYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMMLVGTPGPELLMKISSESA---RTYISSLPHMAK---------------------RNFAD------VFIGANPLAVDLLEKMLVLDTDRRITAAEALEHPYFAQYH----DPDDEPEAEPY--DQSFESRDL 333
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000023035.1 (SMESG000023035.1) HSP 1 Score: 383.259 bits (983), Expect = 4.043e-133 Identity = 187/187 (100.00%), Postives = 187/187 (100.00%), Query Frame = 3
Query: 24 MSYDKKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYTSSYTFAV 584
MSYDKKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYTSSYTFAV
Sbjct: 1 MSYDKKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYTSSYTFAV 187
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000023037.1 (SMESG000023037.1) HSP 1 Score: 267.314 bits (682), Expect = 5.871e-87 Identity = 152/353 (43.06%), Postives = 218/353 (61.76%), Query Frame = 3
Query: 57 HIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSLELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYTSSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEED-VNGLNSFRNEAPNSCRLEKHIEKDVKRTLLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKKIMKKI 1112
++ G G+VF+ +IVA+K I + Q + K IYREICIL +NS + + L DIY + + + +ELCL++P+MEYDL +I ++ L QII+I +QL+MGLKYL + GIIHRD+KP NIGINK++ ++ILDFGLARD +DDLT+YVVTRWYRPLE+F TS YT AVDMWS GCI VELFT + LF +D IL IMG+P +L+ ++ +D V GL +++ A S +L IEK +K +F + +N E + +LI +ML+L+P RI+P A S +F K Y+E +F + D+ D+ E+ ++ I+K+I
Sbjct: 10 YVAGGVSGKVFQGHCKSDGKIVAIKSIQLKYTQKELYKRIYREICILKHLNSDFTLTLWDIYGKYEDEELMELCLIMPFMEYDLKTII--NKFKLEYQQIIQISFQLLMGLKYLNESGIIHRDLKPGNIGINKDMKLRILDFGLARDKQDDLTEYVVTRWYRPLEVFCTSQYTMAVDMWSAGCIIVELFTGKVLFPGKSQIDQCLSILKIMGWPSTEMLDKMNNKDSVLGLELYKDFAAKSNQLLAVIEKPIK------------NFEEE---SNGRSEFSSFATRLIFKMLELDPDKRISPKEALNSDLFTKLASCTSSYTESGCAHEFKVNCFPDSEDV-ENWKENILKEI 344
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000075533.1 (SMESG000075533.1) HSP 1 Score: 174.481 bits (441), Expect = 7.085e-51 Identity = 91/238 (38.24%), Postives = 140/238 (58.82%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGL 746
+Y N I +G +G V + VA+KK+ + K YRE+ I+ ++ + + L+D Y+ + +S ++ L+ P M DL +I ++E L + +VYQ++ GLKY++ IIHRD+KPSNI +N++ ++KILDFGLAR +++T YV TRWYR EI + YT VD+WSVGCI ELFT++PLF ND +D +K+I+ + G PD + + ED
Sbjct: 20 RYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQE--LLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAF 255
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000075533.1 (SMESG000075533.1) HSP 1 Score: 174.481 bits (441), Expect = 1.245e-50 Identity = 91/238 (38.24%), Postives = 140/238 (58.82%), Query Frame = 3
Query: 39 KYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTIYREICILCQINSQYCIYLMDIYSEITNGKSL-ELCLVLPYMEYDLFHVIFSKEYNLRLYQIIKIVYQLIMGLKYLYKCGIIHRDIKPSNIGINKNLDVKILDFGLARDMKDDLTKYVVTRWYRPLEIFYT-SSYTFAVDMWSVGCITVELFTKEPLFKSNDGVDHVKRILSIMGFPDDHVLEGVSEEDVNGL 746
+Y N I +G +G V + VA+KK+ + K YRE+ I+ ++ + + L+D Y+ + +S ++ L+ P M DL +I ++E L + +VYQ++ GLKY++ IIHRD+KPSNI +N++ ++KILDFGLAR +++T YV TRWYR EI + YT VD+WSVGCI ELFT++PLF ND +D +K+I+ + G PD + + ED
Sbjct: 44 RYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQE--LLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAF 279
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000023025.1 (SMESG000023025.1) HSP 1 Score: 166.777 bits (421), Expect = 1.065e-49 Identity = 82/100 (82.00%), Postives = 86/100 (86.00%), Query Frame = 3
Query: 819 LLSDEDATPDSFADSKL*NNISIETTYLVLKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKKIMKKISE 1118
+LSDEDATPDSFAD +LKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKKI+KKIS+
Sbjct: 122 MLSDEDATPDSFAD--------------ILKLIKQMLDLNPGTRITPMLAQVSPIFLKHKCEIVKYSEDPECSQFLCDEHLDNVDLEEDLEKKIIKKISD 207 The following BLAST results are available for this feature:
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30004871 ID=SMED30004871|Name=Mitogen-activated protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1125bpback to top protein sequence of SMED30004871-orf-1 >SMED30004871-orf-1 ID=SMED30004871-orf-1|Name=SMED30004871-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=283bp MSYDKKYVNFTHIRNGCFGRVFKTQNMLTNEIVAVKKINISLCQMQTKKTback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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