Myotubularin-related protein

Overview
NameMyotubularin-related protein
Smed IDSMED30004793
Length (bp)1609
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Myotubularin-related protein (SMED30004793) t-SNE clustered cells

Violin plots show distribution of expression levels for Myotubularin-related protein (SMED30004793) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Myotubularin-related protein (SMED30004793) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Myotubularin-related protein (SMED30004793) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30004793

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
ciliated epithelial cellSMED30004793h1SMcG0016059 dd_Smed_v4_23287_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Myotubularin-related protein vs. Ensembl Human
Match: MTMR2 (myotubularin related protein 2 [Source:HGNC Symbol;Acc:HGNC:7450])

HSP 1 Score: 218.009 bits (554), Expect = 2.435e-63
Identity = 119/370 (32.16%), Postives = 214/370 (57.84%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNP-STEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W I+  NE++E C+TYP   +V     +E ++ +++FR + R   + + + E+++ I RCSQPM+G S  RS  +E YL+ +   SN+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+LA L++D +YR++ GF++LVE+EW   GH+F+ R     +     + SPVFLQ++DC++Q+  +FP  F+FN  +L  +   +   +   F  NS ++R +    K    +W+Y++ S ++   N  +   S  ++    S+++L +W   YI
Sbjct:  142 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD-SNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYIN-SQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 509          
BLAST of Myotubularin-related protein vs. Ensembl Human
Match: MTMR2 (myotubularin related protein 2 [Source:HGNC Symbol;Acc:HGNC:7450])

HSP 1 Score: 218.009 bits (554), Expect = 3.715e-63
Identity = 119/370 (32.16%), Postives = 214/370 (57.84%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNP-STEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W I+  NE++E C+TYP   +V     +E ++ +++FR + R   + + + E+++ I RCSQPM+G S  RS  +E YL+ +   SN+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+LA L++D +YR++ GF++LVE+EW   GH+F+ R     +     + SPVFLQ++DC++Q+  +FP  F+FN  +L  +   +   +   F  NS ++R +    K    +W+Y++ S ++   N  +   S  ++    S+++L +W   YI
Sbjct:  142 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD-SNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYIN-SQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 509          
BLAST of Myotubularin-related protein vs. Ensembl Human
Match: MTMR2 (myotubularin related protein 2 [Source:HGNC Symbol;Acc:HGNC:7450])

HSP 1 Score: 218.009 bits (554), Expect = 3.715e-63
Identity = 119/370 (32.16%), Postives = 214/370 (57.84%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNP-STEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W I+  NE++E C+TYP   +V     +E ++ +++FR + R   + + + E+++ I RCSQPM+G S  RS  +E YL+ +   SN+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+LA L++D +YR++ GF++LVE+EW   GH+F+ R     +     + SPVFLQ++DC++Q+  +FP  F+FN  +L  +   +   +   F  NS ++R +    K    +W+Y++ S ++   N  +   S  ++    S+++L +W   YI
Sbjct:  142 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD-SNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYIN-SQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 509          
BLAST of Myotubularin-related protein vs. Ensembl Human
Match: MTMR2 (myotubularin related protein 2 [Source:HGNC Symbol;Acc:HGNC:7450])

HSP 1 Score: 218.009 bits (554), Expect = 3.715e-63
Identity = 119/370 (32.16%), Postives = 214/370 (57.84%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNP-STEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W I+  NE++E C+TYP   +V     +E ++ +++FR + R   + + + E+++ I RCSQPM+G S  RS  +E YL+ +   SN+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+LA L++D +YR++ GF++LVE+EW   GH+F+ R     +     + SPVFLQ++DC++Q+  +FP  F+FN  +L  +   +   +   F  NS ++R +    K    +W+Y++ S ++   N  +   S  ++    S+++L +W   YI
Sbjct:  142 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD-SNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYIN-SQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 509          
BLAST of Myotubularin-related protein vs. Ensembl Human
Match: MTMR2 (myotubularin related protein 2 [Source:HGNC Symbol;Acc:HGNC:7450])

HSP 1 Score: 218.009 bits (554), Expect = 1.282e-62
Identity = 119/370 (32.16%), Postives = 214/370 (57.84%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNP-STEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W I+  NE++E C+TYP   +V     +E ++ +++FR + R   + + + E+++ I RCSQPM+G S  RS  +E YL+ +   SN+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+LA L++D +YR++ GF++LVE+EW   GH+F+ R     +     + SPVFLQ++DC++Q+  +FP  F+FN  +L  +   +   +   F  NS ++R +    K    +W+Y++ S ++   N  +   S  ++    S+++L +W   YI
Sbjct:  214 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD-SNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYIN-SQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 581          
BLAST of Myotubularin-related protein vs. Ensembl Celegans
Match: mtm-1 (Myotubularin-related protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9N589])

HSP 1 Score: 204.527 bits (519), Expect = 2.078e-58
Identity = 130/380 (34.21%), Postives = 206/380 (54.21%), Query Frame = 2
Query:  506 EFQRLKFDPNE--WVISPKNEKFEFCETYPRYHIV----LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKD----IFTEFIDCCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEIT-REFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNE----NFQFNSMKERIENQK---EIFDVWTYLSQSDMKHLQNTNF--NPSTEIVEIDYSVKNLLIWKEIY 1585
            E++RL   PN   W     N+ ++F ETYPR  ++     +E + F++ L  FR K+R   + + N    + I RCSQPM G S  RS  +E +L  +   +N++  +LLI DARP+ +A  N   GGG E N  Y      FLNI N+  V+D    +    I   + +    AL  SKW+  +  IL  ++K    +  ++ SVLIHC+DGWDRT QLT+LA + +D +YR++ GF +L+E+EW   GHKF +R        +  E SPVF+Q+ DC++QI+ +FP  F+F      +L  C+ D +       F +NS K R++++K        W+Y+ + + K  +N  F    S +++ ++ S+  L +W + Y
Sbjct:  173 EYERLGI-PNSRLWKEVDINKDYKFSETYPRTFVIPTVSWEEGKPFVKKLGEFRSKERIPVLSWINQTTLASISRCSQPMTGISGKRSAEDERHLTNIMN-ANANCRELLILDARPAVNAKLNKAKGGGYEEN--YVNAPLTFLNIHNIHVVRDSLKRLLAALIPRVDEKGYYKALDESKWLNHVQSILEGAVKAVFNVDTEKQSVLIHCSDGWDRTAQLTSLAMIQLDSYYRTIEGFIVLIEKEWCSFGHKFGERIGHGDDNYSDGERSPVFVQFCDCLWQIMRQFPWAFEFT----QELLICMLDELYACRYGTFLYNSEKIRLKDKKCDETTISFWSYVLE-NKKKFRNPMFKHGKSNKVINVNPSLCGLHVWIDYY 543          
BLAST of Myotubularin-related protein vs. Ensembl Celegans
Match: mtm-6 (Myotubularin-related protein 6 [Source:UniProtKB/Swiss-Prot;Acc:G5ED68])

HSP 1 Score: 192.586 bits (488), Expect = 1.911e-53
Identity = 111/377 (29.44%), Postives = 194/377 (51.46%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYP-RYHIVLKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVK-------DIFTEFIDCCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ---EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKER--IENQKEIFDVWTYLSQSDMKH--LQNTNFNPSTEI--VEIDYSVKNLLIWKEIY 1585
            E  R     ++W  S  NE +  C+TYP +           +     FR + R   + Y + + ++ + RC+QP+ G S     +E+  L  +   +N++++ L + D RP  +A+ N   G G E+   Y   +  F +I N+  ++       D  T+  D  E  K+   L+ S W++ +  ++  S+ +A+ I    +S ++HC+DGWDRT Q+ AL +L++DP+YR++HGFQ+L+E++W   GHKF+ RC        E  +E SP+F QWLDCI+QI+ + P  FQFN +YL ++   +       F  N  K+R  +   K    +WT++   D +H    N  ++P+  +  +++D       +W  +Y
Sbjct:  134 EMTRQGITKSQWTESNINEGYTICDTYPNKLWFPTAASTSVLLGSCKFRSRGRLPVLTYFHQQTEAALCRCAQPLTGFSAR--CVEDEKLMELVGKANTNSDNLFLVDTRPRVNAMVNKVQGKGFEDERNYSNMRFHFFDIENIHVMRASQARLLDAVTKCRDVTEYWKT---LEASGWLKHVRSVVECSLFLAESISRG-TSCVVHCSDGWDRTSQVVALCQLLLDPYYRTIHGFQVLIEKDWLGFGHKFDDRCGHVGALNDEAGKEVSPIFTQWLDCIWQIMQQKPRAFQFNERYLIEMHEHVYSCQFGTFIGNCDKDRRDLNLSKRTKSLWTWM---DARHDDYMNPFYSPTAHVALLDLDTRAARFTVWTAMY 501          
BLAST of Myotubularin-related protein vs. Ensembl Celegans
Match: mtm-6 (Myotubularin-related protein 6 [Source:UniProtKB/Swiss-Prot;Acc:G5ED68])

HSP 1 Score: 192.586 bits (488), Expect = 1.957e-53
Identity = 112/377 (29.71%), Postives = 193/377 (51.19%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYP-RYHIVLKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVK-------DIFTEFIDCCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ---EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKER--IENQKEIFDVWTYLSQSDMKH--LQNTNFNPSTEI--VEIDYSVKNLLIWKEIY 1585
            E  R     ++W  S  NE +  C+TYP +           +     FR + R   + Y + + ++ + RC+QP+ G S     +E+  L  +   +N++++ L + D RP  +A+ N   G G E+   Y   +  F +I N+  ++       D  T+  D  E  K+   L+ S W++ +  ++  S+ +A+ I    S V +HC+DGWDRT Q+ AL +L++DP+YR++HGFQ+L+E++W   GHKF+ RC        E  +E SP+F QWLDCI+QI+ + P  FQFN +YL ++   +       F  N  K+R  +   K    +WT++   D +H    N  ++P+  +  +++D       +W  +Y
Sbjct:  132 EMTRQGITKSQWTESNINEGYTICDTYPNKLWFPTAASTSVLLGSCKFRSRGRLPVLTYFHQQTEAALCRCAQPLTGFSAR--CVEDEKLMELVGKANTNSDNLFLVDTRPRVNAMVNKVQGKGFEDERNYSNMRFHFFDIENIHVMRASQARLLDAVTKCRDVTEYWKT---LEASGWLKHVRSVVECSLFLAESISRGTSCV-VHCSDGWDRTSQVVALCQLLLDPYYRTIHGFQVLIEKDWLGFGHKFDDRCGHVGALNDEAGKEVSPIFTQWLDCIWQIMQQKPRAFQFNERYLIEMHEHVYSCQFGTFIGNCDKDRRDLNLSKRTKSLWTWM---DARHDDYMNPFYSPTAHVALLDLDTRAARFTVWTAMY 499          
BLAST of Myotubularin-related protein vs. Ensembl Celegans
Match: mtm-6 (Myotubularin-related protein 6 [Source:UniProtKB/Swiss-Prot;Acc:G5ED68])

HSP 1 Score: 192.586 bits (488), Expect = 5.255e-53
Identity = 112/377 (29.71%), Postives = 193/377 (51.19%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYP-RYHIVLKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVK-------DIFTEFIDCCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ---EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKER--IENQKEIFDVWTYLSQSDMKH--LQNTNFNPSTEI--VEIDYSVKNLLIWKEIY 1585
            E  R     ++W  S  NE +  C+TYP +           +     FR + R   + Y + + ++ + RC+QP+ G S     +E+  L  +   +N++++ L + D RP  +A+ N   G G E+   Y   +  F +I N+  ++       D  T+  D  E  K+   L+ S W++ +  ++  S+ +A+ I    S V +HC+DGWDRT Q+ AL +L++DP+YR++HGFQ+L+E++W   GHKF+ RC        E  +E SP+F QWLDCI+QI+ + P  FQFN +YL ++   +       F  N  K+R  +   K    +WT++   D +H    N  ++P+  +  +++D       +W  +Y
Sbjct:  240 EMTRQGITKSQWTESNINEGYTICDTYPNKLWFPTAASTSVLLGSCKFRSRGRLPVLTYFHQQTEAALCRCAQPLTGFSAR--CVEDEKLMELVGKANTNSDNLFLVDTRPRVNAMVNKVQGKGFEDERNYSNMRFHFFDIENIHVMRASQARLLDAVTKCRDVTEYWKT---LEASGWLKHVRSVVECSLFLAESISRGTSCV-VHCSDGWDRTSQVVALCQLLLDPYYRTIHGFQVLIEKDWLGFGHKFDDRCGHVGALNDEAGKEVSPIFTQWLDCIWQIMQQKPRAFQFNERYLIEMHEHVYSCQFGTFIGNCDKDRRDLNLSKRTKSLWTWM---DARHDDYMNPFYSPTAHVALLDLDTRAARFTVWTAMY 607          
BLAST of Myotubularin-related protein vs. Ensembl Celegans
Match: mtm-6 (Myotubularin-related protein 6 [Source:UniProtKB/Swiss-Prot;Acc:G5ED68])

HSP 1 Score: 192.586 bits (488), Expect = 5.255e-53
Identity = 112/377 (29.71%), Postives = 193/377 (51.19%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYP-RYHIVLKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVK-------DIFTEFIDCCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ---EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKER--IENQKEIFDVWTYLSQSDMKH--LQNTNFNPSTEI--VEIDYSVKNLLIWKEIY 1585
            E  R     ++W  S  NE +  C+TYP +           +     FR + R   + Y + + ++ + RC+QP+ G S     +E+  L  +   +N++++ L + D RP  +A+ N   G G E+   Y   +  F +I N+  ++       D  T+  D  E  K+   L+ S W++ +  ++  S+ +A+ I    S V +HC+DGWDRT Q+ AL +L++DP+YR++HGFQ+L+E++W   GHKF+ RC        E  +E SP+F QWLDCI+QI+ + P  FQFN +YL ++   +       F  N  K+R  +   K    +WT++   D +H    N  ++P+  +  +++D       +W  +Y
Sbjct:  240 EMTRQGITKSQWTESNINEGYTICDTYPNKLWFPTAASTSVLLGSCKFRSRGRLPVLTYFHQQTEAALCRCAQPLTGFSAR--CVEDEKLMELVGKANTNSDNLFLVDTRPRVNAMVNKVQGKGFEDERNYSNMRFHFFDIENIHVMRASQARLLDAVTKCRDVTEYWKT---LEASGWLKHVRSVVECSLFLAESISRGTSCV-VHCSDGWDRTSQVVALCQLLLDPYYRTIHGFQVLIEKDWLGFGHKFDDRCGHVGALNDEAGKEVSPIFTQWLDCIWQIMQQKPRAFQFNERYLIEMHEHVYSCQFGTFIGNCDKDRRDLNLSKRTKSLWTWM---DARHDDYMNPFYSPTAHVALLDLDTRAARFTVWTAMY 607          
BLAST of Myotubularin-related protein vs. Ensembl Fly
Match: mtm (gene:FBgn0025742 transcript:FBtr0079223)

HSP 1 Score: 218.394 bits (555), Expect = 2.640e-63
Identity = 124/379 (32.72%), Postives = 216/379 (56.99%), Query Frame = 2
Query:  482 SYYEVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEIT-REFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIEN--QKEIFDVWTYLSQSDMKHLQN--TNFNPSTEIV-EIDYSVKNLLIWKEIY 1585
            + YE L  E +RL    + W  +  NE +  C++YP    V K   ++F++ ++ FR + R   + + N   ++ I RCSQP++G S  R+  +E+YL  +   +N+ ++KL I DARPSA+AI N   GGG E+   Y   +  FL+I N+  +++   +  + C    +  K   A+ N+ W++ I  IL  +++I   ++   +SV++HC+DGWDRT QLTAL+ L++DP YR++ GF++L+E+EW   GHKF+QR      + +  + SPVFLQ++D ++Q+  +F N F+FN  +L  +   +       F  N+  ER+    + +   +WT+++ S  ++L     +F    E+V     SV+++ +WK +Y
Sbjct:  187 AVYEPLA-ELRRLGVPNDMWRATKLNESYAICDSYPAVWAVPKAASDDFLRRVAQFRSRCRLPVLSWMNPRTQATITRCSQPLVGVSGKRNSDDEAYLSFIME-ANAQSDKLTIMDARPSANAIANKAKGGGYESEDAYKNVEINFLDIHNIHVMRESLRKVKEACFPTTDDSKWQTAIDNTLWLKHIRCILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQRIGHGDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEAERVAEDLKHKTTSLWTHINSSLDQYLNPLFPSFTHGAELVLRPIASVRSVRLWKGLY 563          
BLAST of Myotubularin-related protein vs. Ensembl Fly
Match: mtm (gene:FBgn0025742 transcript:FBtr0345290)

HSP 1 Score: 218.394 bits (555), Expect = 2.640e-63
Identity = 124/379 (32.72%), Postives = 216/379 (56.99%), Query Frame = 2
Query:  482 SYYEVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEIT-REFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIEN--QKEIFDVWTYLSQSDMKHLQN--TNFNPSTEIV-EIDYSVKNLLIWKEIY 1585
            + YE L  E +RL    + W  +  NE +  C++YP    V K   ++F++ ++ FR + R   + + N   ++ I RCSQP++G S  R+  +E+YL  +   +N+ ++KL I DARPSA+AI N   GGG E+   Y   +  FL+I N+  +++   +  + C    +  K   A+ N+ W++ I  IL  +++I   ++   +SV++HC+DGWDRT QLTAL+ L++DP YR++ GF++L+E+EW   GHKF+QR      + +  + SPVFLQ++D ++Q+  +F N F+FN  +L  +   +       F  N+  ER+    + +   +WT+++ S  ++L     +F    E+V     SV+++ +WK +Y
Sbjct:  187 AVYEPLA-ELRRLGVPNDMWRATKLNESYAICDSYPAVWAVPKAASDDFLRRVAQFRSRCRLPVLSWMNPRTQATITRCSQPLVGVSGKRNSDDEAYLSFIME-ANAQSDKLTIMDARPSANAIANKAKGGGYESEDAYKNVEINFLDIHNIHVMRESLRKVKEACFPTTDDSKWQTAIDNTLWLKHIRCILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQRIGHGDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEAERVAEDLKHKTTSLWTHINSSLDQYLNPLFPSFTHGAELVLRPIASVRSVRLWKGLY 563          
BLAST of Myotubularin-related protein vs. Ensembl Fly
Match: CG3530 (gene:FBgn0028497 transcript:FBtr0112940)

HSP 1 Score: 209.149 bits (531), Expect = 1.152e-59
Identity = 128/377 (33.95%), Postives = 210/377 (55.70%), Query Frame = 2
Query:  488 YEVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEFEEFIQ-DLSNFRRKQRFLSVVY-HNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDI-----ALKNSKWIQSISHILYNSIKIAKCIKIDRS-SVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNPST-EIVEIDYSVKNLLIWKEIY 1585
            Y  L+ EF+ +      W +   NEK+E C+TYPR   V KE    +    S FR K R   + Y HN  NK+ I RCSQP+ G S  R + +E  L+ +   +NS+T+ + + D RP  +A+ N   G G EN  FY+  K  FL I N+   +    + ++ CE +   +     AL++S W++ I  IL  S  IA    +D+  SV++HC+DGWDRT Q+ +LA+L+++P+YR++ GFQ L+E++W   GHKF +RC    Q   RE SP+F Q+LDC +Q++S+    F+FN ++L  L   ++      F  N  K+R++ +  +  F +W Y++ + +    N  + P+  E ++ + + + +  W+ +Y
Sbjct:   77 YFKLEAEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHN--NKASICRCSQPLSGFSA-RCLEDEQMLEAI-RKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEQKSPTMSAFINALESSGWLKHIRSILDTSSFIAN--AVDKGVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHI-QTDAREVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMA-NHLNEYINPLYKPNVDEAIKANLAPQCIKFWRGMY 445          
BLAST of Myotubularin-related protein vs. Ensembl Fly
Match: CG3530 (gene:FBgn0028497 transcript:FBtr0072028)

HSP 1 Score: 209.149 bits (531), Expect = 2.310e-59
Identity = 128/377 (33.95%), Postives = 211/377 (55.97%), Query Frame = 2
Query:  488 YEVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEFEEFIQ-DLSNFRRKQRFLSVVY-HNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDI-----ALKNSKWIQSISHILYNSIKIAKCIKIDRS-SVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNPST-EIVEIDYSVKNLLIWKEIY 1585
            Y  L+ EF+ +      W +   NEK+E C+TYPR   V KE    +    S FR K R   + Y HN  NK+ I RCSQP+ G S  R + +E  L+ +   +NS+T+ + + D RP  +A+ N   G G EN  FY+  K  FL I N+   +    + ++ CE +   +     AL++S W++ I  IL  S  IA    +D+  SV++HC+DGWDRT Q+ +LA+L+++P+YR++ GFQ L+E++W   GHKF +RC    Q   RE SP+F Q+LDC +Q++S+    F+FN ++L  L   ++      F  N  K+R++ +  +  F +W Y++    +++ N  + P+  E ++ + + + +  W+ +Y
Sbjct:  127 YFKLEAEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHN--NKASICRCSQPLSGFSA-RCLEDEQMLEAI-RKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEQKSPTMSAFINALESSGWLKHIRSILDTSSFIAN--AVDKGVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHI-QTDAREVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYI-NPLYKPNVDEAIKANLAPQCIKFWRGMY 495          
BLAST of Myotubularin-related protein vs. Ensembl Fly
Match: CG3530 (gene:FBgn0028497 transcript:FBtr0072029)

HSP 1 Score: 208.764 bits (530), Expect = 1.056e-58
Identity = 128/377 (33.95%), Postives = 210/377 (55.70%), Query Frame = 2
Query:  488 YEVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEFEEFIQ-DLSNFRRKQRFLSVVY-HNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDI-----ALKNSKWIQSISHILYNSIKIAKCIKIDRS-SVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNPST-EIVEIDYSVKNLLIWKEIY 1585
            Y  L+ EF+ +      W +   NEK+E C+TYPR   V KE    +    S FR K R   + Y HN  NK+ I RCSQP+ G S  R + +E  L+ +   +NS+T+ + + D RP  +A+ N   G G EN  FY+  K  FL I N+   +    + ++ CE +   +     AL++S W++ I  IL  S  IA  +  D+  SV++HC+DGWDRT Q+ +LA+L+++P+YR++ GFQ L+E++W   GHKF +RC    Q   RE SP+F Q+LDC +Q++S+    F+FN ++L  L   ++      F  N  K+R++ +  +  F +W Y++ + +    N  + P+  E ++ + + + +  W+ +Y
Sbjct:  199 YFKLEAEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHN--NKASICRCSQPLSGFSA-RCLEDEQMLEAI-RKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEQKSPTMSAFINALESSGWLKHIRSILDTSSFIANAV--DKGVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHI-QTDAREVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMA-NHLNEYINPLYKPNVDEAIKANLAPQCIKFWRGMY 567          
BLAST of Myotubularin-related protein vs. Ensembl Zebrafish
Match: mtmr6 (myotubularin related protein 6 [Source:ZFIN;Acc:ZDB-GENE-030131-5557])

HSP 1 Score: 215.698 bits (548), Expect = 5.725e-62
Identity = 112/374 (29.95%), Postives = 206/374 (55.08%), Query Frame = 2
Query:  497 LKHEFQRLKFDPNEWVISPKNEKFEFCETYPR-YHIVLKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSD-----IALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKER--IENQKEIFDVWTYL---SQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIY 1585
            L  EF+R+    ++W ++  N  ++ CETYPR  ++ +   +  I   S FR K RF  + Y   E K+ + RCSQP+ G S     +E+ ++ +  + +N ++  + + D RP  +A+ N   G G EN   Y   + +F+ I N+  ++    + ++   +         + L+NS W++ I  I+  +I +AK + ++ +SVL+HC+DGWDRT Q+ AL  L+MDP+YR++ GF +L+E++W   GHKF  RC     +  +E SP+F Q+L+C++Q+  +FP  F+F+  +L Q+   I+     NF  NS ++R  ++ ++  + +W +L    Q+ +  + + +F  S  ++E      +   W+ +Y
Sbjct:  131 LAAEFERMGVPCDQWQLTDVNRDYKVCETYPRDLYVPITASKPIIVGSSKFRSKGRFPVLTYFYQEKKAAVCRCSQPLSGFSAR--CLEDEHMLQAISKANHNSRNIYVMDTRPKLNALANRAAGKGYENEDNYSNIRFQFVGIENIHVMRGSLQKLLEVVGTRSLSMTDYLVGLENSGWLRHIKAIMDAAIFLAKAVSVEGASVLVHCSDGWDRTAQVCALGSLLMDPYYRTIKGFMVLIEKDWISFGHKFADRCDQLDPD-PKEVSPIFTQFLECVWQLTEQFPQAFEFSEWFLIQIHEHIHSCQFGNFLGNSQRQREDLQLKERTYSLWAHLLSEKQNYLNPVYSPSFAESQPVLEPSTQAYHFKFWRNMY 501          
BLAST of Myotubularin-related protein vs. Ensembl Zebrafish
Match: mtm1 (myotubularin 1 [Source:ZFIN;Acc:ZDB-GENE-051113-128])

HSP 1 Score: 215.698 bits (548), Expect = 6.623e-62
Identity = 124/376 (32.98%), Postives = 213/376 (56.65%), Query Frame = 2
Query:  488 YEVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIEN--QKEIFDVWTYLSQSDMKHLQNTNFNP-STEIVEIDYSVKNLLIWKEIYI 1588
            YE L+ E++R     NEW ++  N+ +E C+TYP   +V  K  E+ ++ ++ FR + R   + + + EN +VI RCSQP++G S  R+  +E YL  +     + T KL I+DARP+ +A+ N   GGG E +  Y   +  FL+I N+  +++   +  D      E      +L+++ W++ I  +L  +I++A  +    SSV++HC+DGWDRT QLT+L+ L++D +YR+L GFQ+L+E+EW   GHKF  R     +    ++ SP+FLQ++DC++Q+  +FP  F+FN + L  +   +       F +N    R  N  + +   +W+Y++ SD     N  + P S+ ++    S+++L +W   YI
Sbjct:  200 YEALE-EYRRQGLPNNEWRVTFINKNYELCDTYPTILVVPYKATEDDLRKVATFRSRCRIPVMSWFHKENHAVITRCSQPLVGMSGKRNKDDERYLDLI--REANGTTKLTIYDARPNVNAVANKATGGGYEGDDAYQNAELVFLDIHNIHVMRESLKKLKDIVYPNVEESHWLSSLESTHWLEHIKLVLSGAIQVADKVS-SGSSVMVHCSDGWDRTAQLTSLSMLMLDSYYRTLRGFQVLMEKEWISFGHKFASRIGHGDKNHADQDRSPIFLQFIDCVWQMTKQFPTAFEFNERLLVVILDHLYSCRFGTFLYNCESVRDSNNVRTKTVSLWSYIN-SDTSLYINPFYTPESSRVLYPVASMRHLELWVTYYI 570          
BLAST of Myotubularin-related protein vs. Ensembl Zebrafish
Match: mtmr2 (myotubularin related protein 2 [Source:NCBI gene;Acc:30644])

HSP 1 Score: 207.994 bits (528), Expect = 3.271e-59
Identity = 114/362 (31.49%), Postives = 212/362 (58.56%), Query Frame = 2
Query:  530 PNE-WVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITR-EFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            PNE W IS  N+ +E C++YP   +V +   ++ ++ +S+FR K R   + + + E+++ ++R SQPM+G++  R   +E  L+ +   +N+ ++KL IFDARPS +A  N   GGG E+   Y   +  FL+I N+  +++   +  +      E       L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+LA +++D  YR++ GFQILVE+EW   GH+F+QR     +  T  + SP+FLQ++DC++Q+  +FP  F+FN  +L  +   +   +   F  NS ++R++ +  K    +W++++    + +     + S+ ++     +++L +W   YI
Sbjct:  197 PNESWRISKLNDHYELCDSYPATLVVPVTITDDELRRVSSFRAKGRIPVLSWIHPESQAAVVRSSQPMVGQNGRRCKEDEKLLQAIMD-ANAQSHKLFIFDARPSVNAAANKMKGGGFESEDAYQNAELVFLDIHNIHVMRESLRKLKEVVYPNIEESHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLALIMLDSHYRTIRGFQILVEKEWLSFGHRFQQRVGHGDKNHTDVDRSPIFLQFIDCVWQMTRQFPAAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRLKEEIPKRTVSLWSFVNSQLEEFVNPLYVHYSSHVLFPTVGIRHLQLWVSYYI 557          
BLAST of Myotubularin-related protein vs. Ensembl Zebrafish
Match: mtmr1b (myotubularin related protein 1b [Source:ZFIN;Acc:ZDB-GENE-050327-48])

HSP 1 Score: 206.838 bits (525), Expect = 8.180e-59
Identity = 119/375 (31.73%), Postives = 207/375 (55.20%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFW-PQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKY----LHQLFFCINDGVNENFQFNSMKERIENQKEIFD----VWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W+IS  N  +E CETYP   ++     E+ ++ ++ FR K+RF  + + + E+++ I+RC QP +G S  R   +E YL+ +   +N+ ++KL IFDAR S  A  N    GG EN  FY   +  FL I N+  +++   +  +      + +     +  + W++ +  +L  +++IA  I+  ++SV++HC+DGWDRT QLT+LA L++D  YRSL GFQ+L+E+EW   GH+F  R           E SP+F+Q++DC++Q+  +FP+ F+FN  +    L  LF C+       F +NS +ER+   KE+++    +W+Y++    +       N    ++    S+++L +W   Y+
Sbjct:  203 EYKRQGLPNESWIISKVNSGYEVCETYPALLVLPSNVTEDELKRVAAFRAKRRFPVLSWIHPESQAAIVRCGQPQVGPSDRRCREDERYLQTILD-ANAQSHKLCIFDARQSTVADTNKAKDGGYENESFYINVELNFLEIPNIHVMRESLRKLKEVVYPAIDQQHWFSNVDATHWLEYVRLLLAGAVRIADRIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDAHYRSLKGFQVLLEKEWLSFGHRFASRVGHGDGNHANSERSPLFVQFIDCVWQMTRQFPSAFEFNELFLITVLDHLFSCLFG----TFLYNSEQERV--SKEVYNKTVSLWSYVNSQIEEFTNPLYVNYEHHVLYPIASLRHLELWVSYYV 570          
BLAST of Myotubularin-related protein vs. Ensembl Zebrafish
Match: mtmr1b (myotubularin related protein 1b [Source:ZFIN;Acc:ZDB-GENE-050327-48])

HSP 1 Score: 206.838 bits (525), Expect = 1.095e-58
Identity = 119/375 (31.73%), Postives = 207/375 (55.20%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFID----CCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFW-PQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKY----LHQLFFCINDGVNENFQFNSMKERIENQKEIFD----VWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W+IS  N  +E CETYP   ++     E+ ++ ++ FR K+RF  + + + E+++ I+RC QP +G S  R   +E YL+ +   +N+ ++KL IFDAR S  A  N    GG EN  FY   +  FL I N+  +++   +  +      + +     +  + W++ +  +L  +++IA  I+  ++SV++HC+DGWDRT QLT+LA L++D  YRSL GFQ+L+E+EW   GH+F  R           E SP+F+Q++DC++Q+  +FP+ F+FN  +    L  LF C+       F +NS +ER+   KE+++    +W+Y++    +       N    ++    S+++L +W   Y+
Sbjct:  225 EYKRQGLPNESWIISKVNSGYEVCETYPALLVLPSNVTEDELKRVAAFRAKRRFPVLSWIHPESQAAIVRCGQPQVGPSDRRCREDERYLQTILD-ANAQSHKLCIFDARQSTVADTNKAKDGGYENESFYINVELNFLEIPNIHVMRESLRKLKEVVYPAIDQQHWFSNVDATHWLEYVRLLLAGAVRIADRIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDAHYRSLKGFQVLLEKEWLSFGHRFASRVGHGDGNHANSERSPLFVQFIDCVWQMTRQFPSAFEFNELFLITVLDHLFSCLFG----TFLYNSEQERV--SKEVYNKTVSLWSYVNSQIEEFTNPLYVNYEHHVLYPIASLRHLELWVSYYV 592          
BLAST of Myotubularin-related protein vs. Ensembl Xenopus
Match: MTMR2 (myotubularin related protein 2 [Source:NCBI gene;Acc:100494494])

HSP 1 Score: 215.312 bits (547), Expect = 1.246e-62
Identity = 116/371 (31.27%), Postives = 212/371 (57.14%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKY----LHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W I+  NE++E C+TYP   +V     ++ ++ ++ FR + R   + + + E+++ I RCSQP+ G +  RS  +E YL+ +   +N+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRTPQLT+LA +++D +YR++ GF++LVE+EW   GH+F QR     +     + SP+FLQ++DC++Q+  +FPN F+FN  +    L  L+ C+      N +   +KE +   +E   +W++++      +     N S+ ++    S +NL +W   YI
Sbjct:  113 EYRRQGIPNESWRITRVNERYELCDTYPACLVVPANISDDELRKIAAFRAQDRIPVLSWIHPESQAAITRCSQPLPGVNGKRSKEDEKYLQSIMD-ANAQSHKVFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESQRKLKEISYPSIQEANWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTPQLTSLAMIMLDGYYRTIRGFEVLVEKEWVSFGHRFYQRTGHGDKNHADADRSPMFLQFIDCVWQMTRQFPNAFEFNEHFLIIILDHLYSCLFGTFLCNCELQKLKEGV--LEESVSLWSFINSQLEDFINPLYVNYSSHVLYPVTSTRNLELWAGYYI 480          
BLAST of Myotubularin-related protein vs. Ensembl Xenopus
Match: MTMR2 (myotubularin related protein 2 [Source:NCBI gene;Acc:100494494])

HSP 1 Score: 216.083 bits (549), Expect = 1.804e-62
Identity = 116/372 (31.18%), Postives = 212/372 (56.99%), Query Frame = 2
Query:  503 HEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKY----LHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
             E++R       W I+  NE++E C+TYP   +V     ++ ++ ++ FR + R   + + + E+++ I RCSQP+ G +  RS  +E YL+ +   +N+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRTPQLT+LA +++D +YR++ GF++LVE+EW   GH+F QR     +     + SP+FLQ++DC++Q+  +FPN F+FN  +    L  L+ C+      N +   +KE +   +E   +W++++      +     N S+ ++    S +NL +W   YI
Sbjct:  139 QEYRRQGIPNESWRITRVNERYELCDTYPACLVVPANISDDELRKIAAFRAQDRIPVLSWIHPESQAAITRCSQPLPGVNGKRSKEDEKYLQSIMD-ANAQSHKVFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESQRKLKEISYPSIQEANWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTPQLTSLAMIMLDGYYRTIRGFEVLVEKEWVSFGHRFYQRTGHGDKNHADADRSPMFLQFIDCVWQMTRQFPNAFEFNEHFLIIILDHLYSCLFGTFLCNCELQKLKEGV--LEESVSLWSFINSQLEDFINPLYVNYSSHVLYPVTSTRNLELWAGYYI 507          
BLAST of Myotubularin-related protein vs. Ensembl Xenopus
Match: MTMR2 (myotubularin related protein 2 [Source:NCBI gene;Acc:100494494])

HSP 1 Score: 215.698 bits (548), Expect = 1.906e-62
Identity = 117/364 (32.14%), Postives = 211/364 (57.97%), Query Frame = 2
Query:  530 PNE-WVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKY----LHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            PNE W I+  NE++E C+TYP   +V     ++ ++ ++ FR + R   + + + E+++ I RCSQP+ G +  RS  +E YL+ +   +N+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRTPQLT+LA +++D +YR++ GF++LVE+EW   GH+F QR     +     + SP+FLQ++DC++Q+  +FPN F+FN  +    L  L+ C+      N +   +KE +   +E   +W++++      +     N S+ ++    S +NL +W   YI
Sbjct:  138 PNESWRITRVNERYELCDTYPACLVVPANISDDELRKIAAFRAQDRIPVLSWIHPESQAAITRCSQPLPGVNGKRSKEDEKYLQSIMD-ANAQSHKVFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESQRKLKEISYPSIQEANWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTPQLTSLAMIMLDGYYRTIRGFEVLVEKEWVSFGHRFYQRTGHGDKNHADADRSPMFLQFIDCVWQMTRQFPNAFEFNEHFLIIILDHLYSCLFGTFLCNCELQKLKEGV--LEESVSLWSFINSQLEDFINPLYVNYSSHVLYPVTSTRNLELWAGYYI 498          
BLAST of Myotubularin-related protein vs. Ensembl Xenopus
Match: MTMR2 (myotubularin related protein 2 [Source:NCBI gene;Acc:100494494])

HSP 1 Score: 216.083 bits (549), Expect = 1.924e-62
Identity = 117/364 (32.14%), Postives = 211/364 (57.97%), Query Frame = 2
Query:  530 PNE-WVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKY----LHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            PNE W I+  NE++E C+TYP   +V     ++ ++ ++ FR + R   + + + E+++ I RCSQP+ G +  RS  +E YL+ +   +N+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRTPQLT+LA +++D +YR++ GF++LVE+EW   GH+F QR     +     + SP+FLQ++DC++Q+  +FPN F+FN  +    L  L+ C+      N +   +KE +   +E   +W++++      +     N S+ ++    S +NL +W   YI
Sbjct:  158 PNESWRITRVNERYELCDTYPACLVVPANISDDELRKIAAFRAQDRIPVLSWIHPESQAAITRCSQPLPGVNGKRSKEDEKYLQSIMD-ANAQSHKVFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESQRKLKEISYPSIQEANWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTPQLTSLAMIMLDGYYRTIRGFEVLVEKEWVSFGHRFYQRTGHGDKNHADADRSPMFLQFIDCVWQMTRQFPNAFEFNEHFLIIILDHLYSCLFGTFLCNCELQKLKEGV--LEESVSLWSFINSQLEDFINPLYVNYSSHVLYPVTSTRNLELWAGYYI 518          
BLAST of Myotubularin-related protein vs. Ensembl Xenopus
Match: MTMR2 (myotubularin related protein 2 [Source:NCBI gene;Acc:100494494])

HSP 1 Score: 216.083 bits (549), Expect = 2.651e-62
Identity = 116/372 (31.18%), Postives = 212/372 (56.99%), Query Frame = 2
Query:  503 HEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKY----LHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
             E++R       W I+  NE++E C+TYP   +V     ++ ++ ++ FR + R   + + + E+++ I RCSQP+ G +  RS  +E YL+ +   +N+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRTPQLT+LA +++D +YR++ GF++LVE+EW   GH+F QR     +     + SP+FLQ++DC++Q+  +FPN F+FN  +    L  L+ C+      N +   +KE +   +E   +W++++      +     N S+ ++    S +NL +W   YI
Sbjct:  167 QEYRRQGIPNESWRITRVNERYELCDTYPACLVVPANISDDELRKIAAFRAQDRIPVLSWIHPESQAAITRCSQPLPGVNGKRSKEDEKYLQSIMD-ANAQSHKVFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESQRKLKEISYPSIQEANWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTPQLTSLAMIMLDGYYRTIRGFEVLVEKEWVSFGHRFYQRTGHGDKNHADADRSPMFLQFIDCVWQMTRQFPNAFEFNEHFLIIILDHLYSCLFGTFLCNCELQKLKEGV--LEESVSLWSFINSQLEDFINPLYVNYSSHVLYPVTSTRNLELWAGYYI 535          
BLAST of Myotubularin-related protein vs. Ensembl Mouse
Match: Mtm1 (X-linked myotubular myopathy gene 1 [Source:MGI Symbol;Acc:MGI:1099452])

HSP 1 Score: 219.935 bits (559), Expect = 7.466e-64
Identity = 128/372 (34.41%), Postives = 214/372 (57.53%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFN--SMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDY---SVKNLLIWKEIYI 1588
            E++R     + W IS  N+ +E CETYP   +V  +  ++ ++ ++ FR + R   + + + ENK VI+RCSQP++G S  R+  +E YL  V   +N  T+KL+I+DARPS +A+ N   GGG E++  Y   +  FL+I N+  +++   +  D      E      +L+++ W++ I  +L  +I++A  +   +SSVL+HC+DGWDRT QLT+LA L++D FYR++ GF+ILV++EW   GHKF  R     +     + SP+FLQ++DC++Q+  +FP  F+FN  +L  +   +       F FN  S +ER +  +    +W+ L  S+    +N  +  + EI  + Y   S+++L +W   YI
Sbjct:  172 EYRRQGLPNHHWRISFINKCYELCETYPALLVVPYRTSDDDLRRIATFRSRNRLPVLSWIHPENKMVIMRCSQPLVGMSGKRNKDDEKYLD-VIRETNKQTSKLMIYDARPSVNAVANKATGGGYESDDAYQNSELSFLDIHNIHVMRESLKKVKDIVYPNIEESHWLSSLESTHWLEHIKLVLTGAIQVADQVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRTIEGFEILVQKEWISFGHKFASRIGHGDKNHADADRSPIFLQFIDCVWQMSKQFPTAFEFNEGFLITVLDHLYSCRFGTFLFNCDSARERQKLTERTVSLWS-LINSNKDKFKNPFY--TKEINRVLYPVASMRHLELWVNYYI 539          
BLAST of Myotubularin-related protein vs. Ensembl Mouse
Match: Mtm1 (X-linked myotubular myopathy gene 1 [Source:MGI Symbol;Acc:MGI:1099452])

HSP 1 Score: 219.935 bits (559), Expect = 7.466e-64
Identity = 128/372 (34.41%), Postives = 214/372 (57.53%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFN--SMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDY---SVKNLLIWKEIYI 1588
            E++R     + W IS  N+ +E CETYP   +V  +  ++ ++ ++ FR + R   + + + ENK VI+RCSQP++G S  R+  +E YL  V   +N  T+KL+I+DARPS +A+ N   GGG E++  Y   +  FL+I N+  +++   +  D      E      +L+++ W++ I  +L  +I++A  +   +SSVL+HC+DGWDRT QLT+LA L++D FYR++ GF+ILV++EW   GHKF  R     +     + SP+FLQ++DC++Q+  +FP  F+FN  +L  +   +       F FN  S +ER +  +    +W+ L  S+    +N  +  + EI  + Y   S+++L +W   YI
Sbjct:  172 EYRRQGLPNHHWRISFINKCYELCETYPALLVVPYRTSDDDLRRIATFRSRNRLPVLSWIHPENKMVIMRCSQPLVGMSGKRNKDDEKYLD-VIRETNKQTSKLMIYDARPSVNAVANKATGGGYESDDAYQNSELSFLDIHNIHVMRESLKKVKDIVYPNIEESHWLSSLESTHWLEHIKLVLTGAIQVADQVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRTIEGFEILVQKEWISFGHKFASRIGHGDKNHADADRSPIFLQFIDCVWQMSKQFPTAFEFNEGFLITVLDHLYSCRFGTFLFNCDSARERQKLTERTVSLWS-LINSNKDKFKNPFY--TKEINRVLYPVASMRHLELWVNYYI 539          
BLAST of Myotubularin-related protein vs. Ensembl Mouse
Match: Mtm1 (X-linked myotubular myopathy gene 1 [Source:MGI Symbol;Acc:MGI:1099452])

HSP 1 Score: 219.935 bits (559), Expect = 7.466e-64
Identity = 128/372 (34.41%), Postives = 214/372 (57.53%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFN--SMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDY---SVKNLLIWKEIYI 1588
            E++R     + W IS  N+ +E CETYP   +V  +  ++ ++ ++ FR + R   + + + ENK VI+RCSQP++G S  R+  +E YL  V   +N  T+KL+I+DARPS +A+ N   GGG E++  Y   +  FL+I N+  +++   +  D      E      +L+++ W++ I  +L  +I++A  +   +SSVL+HC+DGWDRT QLT+LA L++D FYR++ GF+ILV++EW   GHKF  R     +     + SP+FLQ++DC++Q+  +FP  F+FN  +L  +   +       F FN  S +ER +  +    +W+ L  S+    +N  +  + EI  + Y   S+++L +W   YI
Sbjct:  172 EYRRQGLPNHHWRISFINKCYELCETYPALLVVPYRTSDDDLRRIATFRSRNRLPVLSWIHPENKMVIMRCSQPLVGMSGKRNKDDEKYLD-VIRETNKQTSKLMIYDARPSVNAVANKATGGGYESDDAYQNSELSFLDIHNIHVMRESLKKVKDIVYPNIEESHWLSSLESTHWLEHIKLVLTGAIQVADQVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRTIEGFEILVQKEWISFGHKFASRIGHGDKNHADADRSPIFLQFIDCVWQMSKQFPTAFEFNEGFLITVLDHLYSCRFGTFLFNCDSARERQKLTERTVSLWS-LINSNKDKFKNPFY--TKEINRVLYPVASMRHLELWVNYYI 539          
BLAST of Myotubularin-related protein vs. Ensembl Mouse
Match: Mtm1 (X-linked myotubular myopathy gene 1 [Source:MGI Symbol;Acc:MGI:1099452])

HSP 1 Score: 219.935 bits (559), Expect = 7.466e-64
Identity = 128/372 (34.41%), Postives = 214/372 (57.53%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFN--SMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDY---SVKNLLIWKEIYI 1588
            E++R     + W IS  N+ +E CETYP   +V  +  ++ ++ ++ FR + R   + + + ENK VI+RCSQP++G S  R+  +E YL  V   +N  T+KL+I+DARPS +A+ N   GGG E++  Y   +  FL+I N+  +++   +  D      E      +L+++ W++ I  +L  +I++A  +   +SSVL+HC+DGWDRT QLT+LA L++D FYR++ GF+ILV++EW   GHKF  R     +     + SP+FLQ++DC++Q+  +FP  F+FN  +L  +   +       F FN  S +ER +  +    +W+ L  S+    +N  +  + EI  + Y   S+++L +W   YI
Sbjct:  172 EYRRQGLPNHHWRISFINKCYELCETYPALLVVPYRTSDDDLRRIATFRSRNRLPVLSWIHPENKMVIMRCSQPLVGMSGKRNKDDEKYLD-VIRETNKQTSKLMIYDARPSVNAVANKATGGGYESDDAYQNSELSFLDIHNIHVMRESLKKVKDIVYPNIEESHWLSSLESTHWLEHIKLVLTGAIQVADQVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRTIEGFEILVQKEWISFGHKFASRIGHGDKNHADADRSPIFLQFIDCVWQMSKQFPTAFEFNEGFLITVLDHLYSCRFGTFLFNCDSARERQKLTERTVSLWS-LINSNKDKFKNPFY--TKEINRVLYPVASMRHLELWVNYYI 539          
BLAST of Myotubularin-related protein vs. Ensembl Mouse
Match: Mtmr2 (myotubularin related protein 2 [Source:MGI Symbol;Acc:MGI:1924366])

HSP 1 Score: 218.009 bits (554), Expect = 2.073e-63
Identity = 118/370 (31.89%), Postives = 215/370 (58.11%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNP-STEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W I+  NE++E C+TYP   +V     +E ++ +++FR + R   + + + E+++ + RCSQPM+G S  RS  +E YL+ +   SN+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+LA L++D +YR++ GF++LVE+EW   GH+F+ R     +     + SPVFLQ++DC++Q+  +FP  F+FN  +L  +   +   +   F  NS ++R +    K+   +W+Y++ S ++   N  +   S  ++    S+++L +W   YI
Sbjct:  142 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMD-SNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPTIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKKTVSLWSYIN-SQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 509          
BLAST of Myotubularin-related protein vs. UniProt/SwissProt
Match: sp|Q9Z2C5|MTM1_MOUSE (Myotubularin OS=Mus musculus OX=10090 GN=Mtm1 PE=1 SV=2)

HSP 1 Score: 219.935 bits (559), Expect = 5.222e-63
Identity = 128/372 (34.41%), Postives = 214/372 (57.53%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFN--SMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDY---SVKNLLIWKEIYI 1588
            E++R     + W IS  N+ +E CETYP   +V  +  ++ ++ ++ FR + R   + + + ENK VI+RCSQP++G S  R+  +E YL  V   +N  T+KL+I+DARPS +A+ N   GGG E++  Y   +  FL+I N+  +++   +  D      E      +L+++ W++ I  +L  +I++A  +   +SSVL+HC+DGWDRT QLT+LA L++D FYR++ GF+ILV++EW   GHKF  R     +     + SP+FLQ++DC++Q+  +FP  F+FN  +L  +   +       F FN  S +ER +  +    +W+ L  S+    +N  +  + EI  + Y   S+++L +W   YI
Sbjct:  172 EYRRQGLPNHHWRISFINKCYELCETYPALLVVPYRTSDDDLRRIATFRSRNRLPVLSWIHPENKMVIMRCSQPLVGMSGKRNKDDEKYLD-VIRETNKQTSKLMIYDARPSVNAVANKATGGGYESDDAYQNSELSFLDIHNIHVMRESLKKVKDIVYPNIEESHWLSSLESTHWLEHIKLVLTGAIQVADQVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRTIEGFEILVQKEWISFGHKFASRIGHGDKNHADADRSPIFLQFIDCVWQMSKQFPTAFEFNEGFLITVLDHLYSCRFGTFLFNCDSARERQKLTERTVSLWS-LINSNKDKFKNPFY--TKEINRVLYPVASMRHLELWVNYYI 539          
BLAST of Myotubularin-related protein vs. UniProt/SwissProt
Match: sp|Q13614|MTMR2_HUMAN (Myotubularin-related protein 2 OS=Homo sapiens OX=9606 GN=MTMR2 PE=1 SV=4)

HSP 1 Score: 218.009 bits (554), Expect = 6.157e-62
Identity = 119/370 (32.16%), Postives = 214/370 (57.84%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNP-STEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W I+  NE++E C+TYP   +V     +E ++ +++FR + R   + + + E+++ I RCSQPM+G S  RS  +E YL+ +   SN+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+LA L++D +YR++ GF++LVE+EW   GH+F+ R     +     + SPVFLQ++DC++Q+  +FP  F+FN  +L  +   +   +   F  NS ++R +    K    +W+Y++ S ++   N  +   S  ++    S+++L +W   YI
Sbjct:  214 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD-SNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYIN-SQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 581          
BLAST of Myotubularin-related protein vs. UniProt/SwissProt
Match: sp|Q13496|MTM1_HUMAN (Myotubularin OS=Homo sapiens OX=9606 GN=MTM1 PE=1 SV=2)

HSP 1 Score: 217.238 bits (552), Expect = 6.344e-62
Identity = 127/372 (34.14%), Postives = 216/372 (58.06%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEIT-REFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFN--SMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDY---SVKNLLIWKEIYI 1588
            E++R     + W I+  N+ +E C+TYP   +V  +  ++ ++ ++ FR + R   + + + ENK+VI+RCSQP++G S  R+  +E YL  V   +N   +KL I+DARPS +A+ N   GGG E++  Y   +  FL+I N+  +++   +  D      E      +L+++ W++ I  +L  +I++A  +   +SSVL+HC+DGWDRT QLT+LA L++D FYRS+ GF+ILV++EW   GHKF  R     +  T  + SP+FLQ++DC++Q+  +FP  F+FN ++L  +   +       F FN  S +ER +  +    +W+ L  S+ +  +N  +  + EI  + Y   S+++L +W   YI
Sbjct:  172 EYRRQGLPNHHWRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENKTVIVRCSQPLVGMSGKRNKDDEKYLD-VIRETNKQISKLTIYDARPSVNAVANKATGGGYESDDAYHNAELFFLDIHNIHVMRESLKKVKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRSIEGFEILVQKEWISFGHKFASRIGHGDKNHTDADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLIIILDHLYSCRFGTFLFNCESARERQKVTERTVSLWS-LINSNKEKFKNPFY--TKEINRVLYPVASMRHLELWVNYYI 539          
BLAST of Myotubularin-related protein vs. UniProt/SwissProt
Match: sp|Q9Z2D1|MTMR2_MOUSE (Myotubularin-related protein 2 OS=Mus musculus OX=10090 GN=Mtmr2 PE=1 SV=3)

HSP 1 Score: 218.009 bits (554), Expect = 6.616e-62
Identity = 118/370 (31.89%), Postives = 215/370 (58.11%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNP-STEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W I+  NE++E C+TYP   +V     +E ++ +++FR + R   + + + E+++ + RCSQPM+G S  RS  +E YL+ +   SN+ ++K+ IFDARPS +A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       +      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+LA L++D +YR++ GF++LVE+EW   GH+F+ R     +     + SPVFLQ++DC++Q+  +FP  F+FN  +L  +   +   +   F  NS ++R +    K+   +W+Y++ S ++   N  +   S  ++    S+++L +W   YI
Sbjct:  214 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMD-SNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPTIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKKTVSLWSYIN-SQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 581          
BLAST of Myotubularin-related protein vs. UniProt/SwissProt
Match: sp|Q6AXQ4|MTM1_RAT (Myotubularin OS=Rattus norvegicus OX=10116 GN=Mtm1 PE=2 SV=2)

HSP 1 Score: 216.853 bits (551), Expect = 9.210e-62
Identity = 118/369 (31.98%), Postives = 200/369 (54.20%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDI----ALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFN--SMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W IS  N+++E C+TYP   +V  +  ++ ++ ++ FR + R   + + + EN++ I+RCSQP++G    RS  +E YL  +   +N  T+KL I+DARP  +A+ N   GGG E    Y   +  FL+I N+  +++      D       +     +L+++ W++ I  +L  +I++A  +    SSVL+HC+DGWDRT QLT LA L++D FYRS+ GF+ILV++EW   GHKF  R     +     + SP+FLQ++DC++Q+  +FP  F+FN  +L  +   +       F  N  + +ER    +    VW+ ++ +  +         S  ++    SV++L +W   YI
Sbjct:  172 EYRRQGLPDRHWRISFVNQRYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENRAAIMRCSQPLVGVGGKRSRDDERYLD-IIRETNKQTSKLTIYDARPGVNAVANKATGGGYEGEDAYPHAELSFLDIHNIHVMRESLRRVRDIVYPHVEEAHWLSSLESTHWLEHIKLLLTGAIRVADKVASGLSSVLVHCSDGWDRTAQLTTLAMLMLDGFYRSIEGFEILVQKEWISFGHKFSSRIGHGDKNHADADRSPIFLQFIDCVWQMTKQFPTAFEFNECFLVAILDHLYSCRFGTFLLNCEAARERQRLAERTVSVWSLINSNKDEFTNPFYARESNRVIYPVTSVRHLELWVNYYI 539          
BLAST of Myotubularin-related protein vs. TrEMBL
Match: A0A068YD00 (Myotubularin protein 3 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_001013800 PE=4 SV=1)

HSP 1 Score: 249.98 bits (637), Expect = 1.963e-68
Identity = 135/381 (35.43%), Postives = 220/381 (57.74%), Query Frame = 2
Query:  491 EVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRV---------CALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSD--IALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEI-TREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            E++  EF RL+FD N W I+  N  F+ C++YP+YHI+ ++  ++ I +++ FR   RF SVV+ +    +V++RC+QP +G   +RS  +E ++  +            S+ D+  LLI DAR  + A  N   GGG E   +YD  +  F ++ N+  V+  F   +   +   S     L+ S W+  IS +L ++++IA  + ++   V++HCTDGWDRTPQLT+LA+L++DP+YR++ GF+IL+E+EW Q GHKF +RC        + E SP+FLQWLDC+ QI  +FP+ F+FN  +L ++      G+   F  NS  ER EN+   +   +W YL+ +    + N  +    E++   + V NL +W  +Y+
Sbjct:   33 EMILQEFNRLEFD-NNWKITDVNSDFQICKSYPKYHILPRDVSDQDIPNIATFRSHHRFPSVVWRSCRTGAVLLRCAQPRVGIMYSRSEYDERFVAAILENCRKDPLSKQSHGDSCNLLIIDARYYSSAQFNRLRGGGFEYKEYYDQSQIRFADLPNLHAVRMSFERLMLLYKKPDSSWLATLERSLWLSYISQLLKSAVEIAAALDVNGRPVMVHCTDGWDRTPQLTSLAELLLDPYYRTIRGFRILIEREWLQFGHKFGERCGHSLNSCSSEEQSPIFLQWLDCVRQIQRQFPHCFEFNELFLVKIAIHTYSGLFGTFLCNSELERQENRCASQTCSIWAYLNPNYNWSIINYLYEEKNEVINPAWHVSNLELWDTLYV 412          
BLAST of Myotubularin-related protein vs. TrEMBL
Match: A0A0X3PVE4 (Myotubularin-related protein 3 OS=Schistocephalus solidus OX=70667 GN=MTMR3 PE=4 SV=1)

HSP 1 Score: 249.21 bits (635), Expect = 4.659e-68
Identity = 133/378 (35.19%), Postives = 219/378 (57.94%), Query Frame = 2
Query:  503 HEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEFEEF-IQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSN-----------SDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSD---IALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIY 1585
            +EF+RL+F   +W ++  N +F  C +YP+YHI+ ++ ++  I  ++ FR   RF SVV+ + +  +V++RC+QP +G   +R+ ++E ++K V  LSN            D  +LLI DAR  + A  N   GGG E   +Y+  +  F+++ N+  V+  F       ES+       AL+ + W+  IS ++ ++ ++A  +      V++HCTDGWDRTPQLT+LAK+++DPFYR++ GF+ILVE EW Q GHKF  RC         E SP+FLQWLDC+ Q+  +FP  F+FN  +L +L      G+   F FNS ++R   Q  ++   +W +L+ +    L+N  + P  E+++  + V++L +W  +Y
Sbjct:  156 YEFERLEFS-KDWKVTDVNSEFGICRSYPKYHIMPRDIKDNDIPSMATFRSHNRFPSVVWRSRKTGAVLLRCAQPCVGIMYSRNELDEHFVKSV--LSNCRNDHKVKNRGEDPPRLLIIDARNYSAAQLNRLRGGGFEYVEYYEQSQIRFMDLPNLHSVRLSFERLTQLYESKPETNWYSALEKTLWLYYISQLIKSASEVAAALDAHCRPVMVHCTDGWDRTPQLTSLAKILLDPFYRTIQGFRILVEHEWLQFGHKFGDRCGHNSSSGPEERSPIFLQWLDCVRQVHRQFPAYFEFNELFLIKLAMHTYSGLFGTFLFNSERDRHVAQCSQQTCSLWAFLNPTRNWSLRNYLYEPKQEVIKPAWQVRSLELWDALY 530          
BLAST of Myotubularin-related protein vs. TrEMBL
Match: A0A564YS64 (Myotubularin phosphatase domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS8884 PE=4 SV=1)

HSP 1 Score: 247.284 bits (630), Expect = 4.849e-68
Identity = 135/386 (34.97%), Postives = 222/386 (57.51%), Query Frame = 2
Query:  479 DSYYE--VLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCA---------LSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSD--IALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAF-WPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQKEI--FDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIY 1585
            D+ +E  ++ +EF+RL+F+ ++W I+ +N  F  C++YPRYHI+ +   ++ I  +++FR   RF SVV+ + +  +V++RC+QP +G   +R+ ++E ++  V            S+ D++KLLI DAR    A  N   GGG E   +YD  +  F+N+ N+  V+  F   I    +  S     ++ + W+  IS +L +++ I   +++    V++HCTDGWDRTPQLT+LAKL++DP+YR++ GF+ LVE+EW Q GHKF  RC   + +    E SPVFLQWLDC+ QI  +FP  F+FN  +L ++      G+   F  NS  ER   QK +    +W +L+      + N  +  + E++   + V  L +W  +Y
Sbjct:  151 DTSFEASMVYNEFERLEFN-SDWKITDENSSFRICKSYPRYHIMPRGVSDQDISSMASFRSHHRFPSVVWRSRKTGAVLLRCAQPCVGIMYSRNELDERFVTAVLENCRKVSHPNQSDEDSHKLLIIDARDYTAAQFNRFRGGGFEFGEYYDQSQIRFMNLPNLHYVRKSFEALIALYRNPDSSWLQKVETTMWLSYISQLLKSAVDIVAALEVHSRPVMVHCTDGWDRTPQLTSLAKLLLDPYYRTIEGFRFLVEREWLQFGHKFADRCGHSFSRTSPEEQSPVFLQWLDCVHQIQLQFPGHFEFNELFLLKIAIHTYSGLFGTFLCNSEYERQTEQKSLPSCSLWAFLNPKYNWSILNYLYKSNDEVITPAHHVSGLALWHNLY 535          
BLAST of Myotubularin-related protein vs. TrEMBL
Match: A0A0R3SYK0 (Myotubularin phosphatase domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS10843 PE=4 SV=1)

HSP 1 Score: 247.284 bits (630), Expect = 5.637e-68
Identity = 135/386 (34.97%), Postives = 222/386 (57.51%), Query Frame = 2
Query:  479 DSYYE--VLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCA---------LSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSD--IALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAF-WPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQKEI--FDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIY 1585
            D+ +E  ++ +EF+RL+F+ ++W I+ +N  F  C++YPRYHI+ +   ++ I  +++FR   RF SVV+ + +  +V++RC+QP +G   +R+ ++E ++  V            S+ D++KLLI DAR    A  N   GGG E   +YD  +  F+N+ N+  V+  F   I    +  S     ++ + W+  IS +L +++ I   +++    V++HCTDGWDRTPQLT+LAKL++DP+YR++ GF+ LVE+EW Q GHKF  RC   + +    E SPVFLQWLDC+ QI  +FP  F+FN  +L ++      G+   F  NS  ER   QK +    +W +L+      + N  +  + E++   + V  L +W  +Y
Sbjct:  151 DTSFEASMVYNEFERLEFN-SDWKITDENSSFRICKSYPRYHIMPRGVSDQDISSMASFRSHHRFPSVVWRSRKTGAVLLRCAQPCVGIMYSRNELDERFVTAVLENCRKVSHPNQSDEDSHKLLIIDARDYTAAQFNRFRGGGFEFGEYYDQSQIRFMNLPNLHYVRKSFEALIALYRNPDSSWLQKVETTMWLSYISQLLKSAVDIVAALEVHSRPVMVHCTDGWDRTPQLTSLAKLLLDPYYRTIEGFRFLVEREWLQFGHKFADRCGHSFSRTSPEEQSPVFLQWLDCVHQIQLQFPGHFEFNELFLLKIAIHTYSGLFGTFLCNSEYERQTEQKSLPSCSLWAFLNPKYNWSILNYLYKSNDEVITPAHHVSGLALWHNLY 535          
BLAST of Myotubularin-related protein vs. TrEMBL
Match: A0A0R3VVR4 (Myotubularin phosphatase domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS1491 PE=4 SV=1)

HSP 1 Score: 247.284 bits (630), Expect = 2.151e-67
Identity = 139/390 (35.64%), Postives = 220/390 (56.41%), Query Frame = 2
Query:  491 EVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYL-------KRVCALSN--SDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSD-----------IALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEI-TREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            E++  EF RL+F+ N W I+  N  F+ C +YP+YHIV ++  ++ I +++ FR + RF SVV+ + +  +V++RC+QP +G   +RS  +E ++       +R   L N   D++KLLI DAR  + A  N   GGG E   +YD  +  F+ + N+  V+  F   +  C+   S              L+ S W+  IS +L +++ IA  + +    V++HCTDGWDRTPQLT+LA+L++DP+YR++ GF++L+E+EW Q GHKF  RC        + E SPVFLQWLDC+ QI  +FP+ F+FN  +L +L      G+   F  NS  ER EN        +W YL+ +    + N  +    E+++    + NL +W  +Y+
Sbjct:  118 EMILQEFNRLEFN-NNWKITDVNSDFQVCNSYPKYHIVPRDISDQAIPNIATFRSQHRFPSVVWRSRKTGAVLLRCAQPRVGIMCSRSDSDEKFVAAIFENCRRDPLLKNRQEDSHKLLIIDARCYSSAQLNRLRGGGFEYMEYYDQSEIRFMELPNLHYVRISFERLMLLCKKPDSRQDSSIDPPYWLTTLERSLWLSYISQLLKSAVDIAVALDVQGFPVMVHCTDGWDRTPQLTSLAELLLDPYYRTIRGFRVLIEREWVQFGHKFGDRCGHKLNPCRSEEQSPVFLQWLDCVRQIQRQFPHCFEFNELFLVKLAIHAYSGLFGTFLCNSELERQENHCASRTCSIWAYLNPNYNWSIMNYLYEERNEVIKPACHISNLELWDTLYV 506          
BLAST of Myotubularin-related protein vs. Ensembl Cavefish
Match: mtmr1b (myotubularin-related protein 1-like [Source:NCBI gene;Acc:111191475])

HSP 1 Score: 217.624 bits (553), Expect = 9.827e-63
Identity = 122/372 (32.80%), Postives = 214/372 (57.53%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFID----CCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQKEIF----DVWTYLSQSDMKHLQNTNF-NPSTEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W+IS  N  +E CETYP   ++     E+ ++ ++ FR K+RF  + + + E+++ I+RC QP +G S  R   +E YL+ V   +N+ ++KL I+DAR S+ A  N    GG EN  FY   +  FL I N+  +++   +  +      + ++   ++  + W++ I  +L  +++IA  I+  ++SV++HC+DGWDRT QLT+LA L++D +YRSL GFQ+L+E+EW   GH+F  R     Q     E SP+F+Q++DC++Q+  +FP+ F+FN  +L  +   +   +   F +NS +ER+   KE+F     +W+Y++ S ++   N  + N    ++    S++NL +W   Y+
Sbjct:  217 EYKRQGLPNESWLISKINSSYEVCETYPALLVLPASISEDELKRVAAFRAKRRFPVLSWIHPESQAAIVRCGQPQVGPSDRRCREDERYLQTVLD-ANAQSHKLCIYDARQSSVADTNKAKDGGYENESFYPNVELNFLEIPNIHVMRESLRKLKEVVYPAIDEQRWFSSVDATHWLEYIRLLLAGAVRIADRIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRSLRGFQVLLEKEWLSFGHRFASRVGHGDQNHANSERSPLFVQFIDCVWQMTRQFPSAFEFNELFLITMLDHLYSCLFGTFLYNSEQERV--SKEVFSKTVSLWSYIN-SQVEDFSNPLYVNCEHHVLYPVASLRNLELWVSYYV 584          
BLAST of Myotubularin-related protein vs. Ensembl Cavefish
Match: mtmr1b (myotubularin-related protein 1-like [Source:NCBI gene;Acc:111191475])

HSP 1 Score: 217.624 bits (553), Expect = 1.631e-62
Identity = 122/372 (32.80%), Postives = 214/372 (57.53%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFID----CCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQKEIF----DVWTYLSQSDMKHLQNTNF-NPSTEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W+IS  N  +E CETYP   ++     E+ ++ ++ FR K+RF  + + + E+++ I+RC QP +G S  R   +E YL+ V   +N+ ++KL I+DAR S+ A  N    GG EN  FY   +  FL I N+  +++   +  +      + ++   ++  + W++ I  +L  +++IA  I+  ++SV++HC+DGWDRT QLT+LA L++D +YRSL GFQ+L+E+EW   GH+F  R     Q     E SP+F+Q++DC++Q+  +FP+ F+FN  +L  +   +   +   F +NS +ER+   KE+F     +W+Y++ S ++   N  + N    ++    S++NL +W   Y+
Sbjct:  240 EYKRQGLPNESWLISKINSSYEVCETYPALLVLPASISEDELKRVAAFRAKRRFPVLSWIHPESQAAIVRCGQPQVGPSDRRCREDERYLQTVLD-ANAQSHKLCIYDARQSSVADTNKAKDGGYENESFYPNVELNFLEIPNIHVMRESLRKLKEVVYPAIDEQRWFSSVDATHWLEYIRLLLAGAVRIADRIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRSLRGFQVLLEKEWLSFGHRFASRVGHGDQNHANSERSPLFVQFIDCVWQMTRQFPSAFEFNELFLITMLDHLYSCLFGTFLYNSEQERV--SKEVFSKTVSLWSYIN-SQVEDFSNPLYVNCEHHVLYPVASLRNLELWVSYYV 607          
BLAST of Myotubularin-related protein vs. Ensembl Cavefish
Match: mtmr6 (myotubularin related protein 6 [Source:NCBI gene;Acc:103033736])

HSP 1 Score: 206.838 bits (525), Expect = 8.333e-59
Identity = 112/374 (29.95%), Postives = 202/374 (54.01%), Query Frame = 2
Query:  497 LKHEFQRLKFDPNEWVISPKNEKFEFCETYPR-YHIVLKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDI-----ALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYL---SQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIY 1585
            L  EF+R+    ++W ++  N  ++ CETYPR  ++ +   +  I   S FR K RF  + Y   E K+ + RCSQP+ G S     +E+ ++ +  + +N +   + + D RP  +A+ N   G G EN   Y   + +F+ I N+  ++    + ++   +    +      L+NS W++ I  I+  +I + K + ++ +SVL+HC+DGWDRT Q+ +L  L+MDP+YR++ GF +L+E++W   GHKF  RC     ++ +E SP+F Q+L+ ++Q+  +FP  FQF+  +L Q+   ++     NF  NS ++R E Q  +    +W +L    Q+ +  L + +F  S  ++E      +   W+ +Y
Sbjct:  131 LGAEFERMGVPCDQWQLTDVNRDYKVCETYPRDLYVPITASKPIIVGSSKFRSKGRFPVLTYFYQEKKAAVCRCSQPLSGFSAR--CLEDEHMLQAISKANHNNRYVYVMDTRPKLNALANRAAGKGYENEDNYSNIRFQFVGIENIHVMRASLQKLLEVVGTRSLSVTDYLEGLENSGWLRHIKAIVDAAIFLTKAVTLEGASVLVHCSDGWDRTAQVCSLGALLMDPYYRTIKGFMVLIEKDWIAFGHKFADRCDQLDGDL-KEVSPIFTQFLESVWQLTEQFPQAFQFSEWFLIQIHEHVHSCQFGNFLGNSQRQREELQLKERTHSLWAHLISEQQNYLNPLYSPSFAESHPVLEPSTQAWHFKFWRNMY 501          
BLAST of Myotubularin-related protein vs. Ensembl Cavefish
Match: mtm1 (myotubularin 1 [Source:ZFIN;Acc:ZDB-GENE-051113-128])

HSP 1 Score: 204.912 bits (520), Expect = 1.205e-58
Identity = 120/382 (31.41%), Postives = 211/382 (55.24%), Query Frame = 2
Query:  470 KPTDSYYEVLKHEFQRLKFDPNE-WVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFN--SMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            KP D Y         R +  PNE W IS  N  +E C+TYP   +V  K  EE ++ ++ FR + R   + + + +N++VI+RCSQP++G S  R+  +E YL  +     + T KL I+DARP+ +A+ N   GGG E +  Y   +  FL+I N+  +++   +  D      E      +L+++ W++ I  +L  +I++A  +    +SV++HC+DGWDRT QLT+L+ L++D ++R+  GFQ+L+E+EW   GHKF  R     +    ++ SP+FLQ++DC++Q+  +FP  F+FN  +L  +   +       F +N  S++E    + +   +W+ ++ S   ++       S+ ++    S+++L +W   YI
Sbjct:  140 KPMDEY---------RRQGLPNERWRISFINSNYELCDTYPTILVVPFKATEEDLRRVATFRSRCRIPVLSWIHRDNQAVIMRCSQPLVGMSGKRNKDDERYLDII--REANGTTKLTIYDARPNVNAVANKATGGGYEGDDAYQNAELVFLDIHNIHVMRESLKKLKDIVYPNVEESHWLSSLESTHWLEHIKLVLSGAIQVADKVS-SGNSVVVHCSDGWDRTAQLTSLSMLMLDSYFRTFRGFQVLLEKEWIGFGHKFASRIGHGDKNHADQDRSPIFLQFIDCVWQMTKQFPTAFEFNEHFLITVLDHLYSCRFGTFLYNCESVRENYNVRAKTVSLWSLINSSTSIYMNPFYTAESSHVLYPVASMRHLELWVNYYI 509          
BLAST of Myotubularin-related protein vs. Ensembl Cavefish
Match: mtmr2 (myotubularin related protein 2 [Source:NCBI gene;Acc:103046532])

HSP 1 Score: 206.068 bits (523), Expect = 1.707e-58
Identity = 113/369 (30.62%), Postives = 208/369 (56.37%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC----ESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEIT-REFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            E++R       W IS  N+ +E C++YP   +V +   ++ ++ ++ FR K R   + + + E+++ ++RCSQPM G S  R   +E  L+ +   +N+ ++K+ IFDARPS +A  N   GGG E+   Y   +  FL+I N+  +++   +  +      E       L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+L+ +++D  YR++ GFQ L+E+EW   GH+F+QR     Q  T  + SP+FLQ++DC++Q+  +FP  F+FN  +L  L   +   +   F  NS ++R++ +  K    VW+ ++    + +     +    ++    S+++L +W   YI
Sbjct:  208 EYRRQGLPNESWRISKVNDHYELCDSYPAALVVPVTITDDELRRVAAFRAKGRIPVLSWLHPESQAAVVRCSQPMSGVSGKRCKEDEKLLQAIMD-ANAQSHKIFIFDARPSVNAAANKMKGGGCESEDAYQNAELVFLDIHNIHVMRESLRKLKEVVYPNIEESHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLSLIMLDSHYRTVTGFQKLIEKEWISFGHRFQQRVGHGDQNHTDADRSPIFLQFIDCVWQMTQQFPAAFEFNEYFLITLLDQLYSCLFGTFLCNSEQQRVKEELVKRTVSVWSLVNSQLEEFVNPLYVHYPAHVLLPSVSIRHLQLWVSYYI 575          
BLAST of Myotubularin-related protein vs. Ensembl Sea Lamprey
Match: mtm1 (myotubularin 1 [Source:ZFIN;Acc:ZDB-GENE-051113-128])

HSP 1 Score: 232.646 bits (592), Expect = 1.798e-69
Identity = 120/371 (32.35%), Postives = 211/371 (56.87%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLK-EFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDI----ALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKY----LHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            E+QRL  D   W IS  NE +E C+TYP   +V +   ++ ++  + FR + R   + + +  N + + RCSQP +G S  RS  +E YL+ +   + S + +L I+DARP  +AI N   GGG E    Y   +  FL+I N+  +++   +  +      ++     +L+ + W++ I  +L  +I+IA+ ++++R+SVL+HC+DGWDRT QL+ALA L++DP+YR+L GF++LVE+EW   GHKF+QR     +     + SP+FLQ++DC++Q+  +FP  F+FN ++    L  L+ C+      N +    +ER   +++   +W+ ++    + +        T ++   +S++ L +W   YI
Sbjct:  156 EYQRLGMDNPPWKISKLNESYELCDTYPTVLVVPRNATDDDLRRTAAFRSRGRLPVLSWLHPRNLASLTRCSQPQVGVSGKRSREDERYLQLIMMANASQSRRLAIYDARPGVNAIANKAKGGGYETEEAYPFAEFVFLDIHNIHVMRESLRKLKELVFPTVTESRWLSSLEATHWLEHIKAVLSGAIQIAEKLELERTSVLVHCSDGWDRTAQLSALAMLLLDPYYRTLRGFEVLVEKEWVSSGHKFQQRVGHGDKNHADSDRSPIFLQFVDCVWQLTKQFPTAFEFNERFLIMLLDNLYSCLYGTFMGNCEKGRRQER--TREKTVSLWSMVNSRQQEFISPLYDREYTRVLTPVHSMRQLQLWVSYYI 524          
BLAST of Myotubularin-related protein vs. Ensembl Sea Lamprey
Match: mtmr9 (myotubularin related protein 9 [Source:ZFIN;Acc:ZDB-GENE-040724-223])

HSP 1 Score: 175.252 bits (443), Expect = 1.842e-48
Identity = 114/386 (29.53%), Postives = 196/386 (50.78%), Query Frame = 2
Query:  479 DSYYEVL-KHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEFE-EFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDI-----ALKNSKWIQSISHILYNSIKIAKCIKIDR----SSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRC--AFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIEN--QKEIFDVWTYLSQSD-MKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            D ++  L +HEF RL     +W +S  N+ F  C +YP   I+ K  + E ++ +S FR+  RF  + Y++  N  V++RCSQP+ G    R   +E  +  V         +  I D R    A +    GGG E    Y   +    +I     ++D F + ++ C     ++      L+ S W+  I  IL  +   A+C+   R    +SVL+H +DG D T Q++ALA++I+D   R+L GFQ LVE+EW Q GH F++RC  + +     R+ +P FL +LDC  QI  +FP  F+F  ++L  LF          F  NS  ER++   Q++   +W+++++ + M+   N  + P+   +    + ++L++W+ +++
Sbjct:  122 DGWHSFLPEHEFTRLTSHTADWRLSHVNKDFTVCPSYPPVVIIPKAIDDEMVKKVSAFRQNGRFPVLSYYHKTNGMVMMRCSQPLTGSGGKRCKDDEKLVNAVLG----PGKRGYIIDTRSLHIAQQARAKGGGYEPEAHYPQWRRINKSIERYNLMQDSFIKLVEACNDPSHNMDRWLSKLEASNWLGHIKDILTAACLAAQCLDSARTREGASVLVHGSDGTDSTLQVSALAQVILDQDCRTLRGFQALVEREWLQAGHPFQERCSRSAFANVKPRQEAPSFLLFLDCCQQIQRQFPCSFEFGERFLVLLFEHAYASQFGTFLCNSELERMKMKVQQKTVSMWSWVNRPEVMEQYLNPLYEPNNLAIWPSVAPQSLVLWEGVFL 503          
BLAST of Myotubularin-related protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002170.1 (pep scaffold:Pmarinus_7.0:GL484749:1247:6808:1 gene:ENSPMAG00000001972.1 transcript:ENSPMAT00000002170.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 120.553 bits (301), Expect = 1.004e-31
Identity = 55/132 (41.67%), Postives = 88/132 (66.67%), Query Frame = 2
Query: 1088 SVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKER--IENQKEIFDVWTYL 1477
            SVL+HC+DGWDRT Q+ ++A++++DP+YR+L GF +L+E+EW   GHKF QRC F  +   RE SPVFLQ L+C++Q+  +FP  F+F+ + L  +    +     NF  N  +ER  +  +++ + +W +L
Sbjct:    9 SVLVHCSDGWDRTAQVCSVAEILLDPYYRTLRGFLVLIEKEWISFGHKFSQRCGF-VEGDAREVSPVFLQLLECVWQLSLQFPCAFEFSERLLTSVHAHTHSCQFGNFLGNCERERAQLRVKEKTYSLWAFL 139          
BLAST of Myotubularin-related protein vs. Ensembl Sea Lamprey
Match: sbf1 (SET binding factor 1 [Source:ZFIN;Acc:ZDB-GENE-040718-139])

HSP 1 Score: 106.686 bits (265), Expect = 2.588e-24
Identity = 49/119 (41.18%), Postives = 72/119 (60.50%), Query Frame = 2
Query: 1085 SSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIE 1441
            SSV++   +GWD T QL ++ +L+ DPFYR+L GF++LVE+EW   GH+F  R            +P+FLQ+LDC+ Q+ ++FP +F+FN  YL  L +         F  +S  ERIE
Sbjct: 1434 SSVMVSLEEGWDITTQLVSMVQLLSDPFYRTLDGFRLLVEKEWISFGHRFSHRSNQTLASQGSGLAPLFLQFLDCVHQVHNQFPTEFEFNQYYLKFLAYHFVSNRFRTFLLDSDYERIE 1552          
BLAST of Myotubularin-related protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010382.1 (pep scaffold:Pmarinus_7.0:GL482471:369374:413667:1 gene:ENSPMAG00000009395.1 transcript:ENSPMAT00000010382.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 101.679 bits (252), Expect = 8.972e-23
Identity = 54/155 (34.84%), Postives = 82/155 (52.90%), Query Frame = 2
Query:  998 ALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWD-------RTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIE 1441
            AL+ S+W+  +  I++    +   I+    S  I C    D          Q+ +L +L+ DPFYR+L GF++L+E+EW   GH+F QR        +  F+PVFLQ+LDC+ Q+  +FP +F+FN  YL  L +         F  +S  ERIE
Sbjct: 1226 ALEQSEWLPQVPSIVFRDAIMVHSIENASGSCQI-CEANLDCPPPPPCSASQVVSLVQLLSDPFYRTLDGFRLLIEKEWLAFGHRFGQRSNMGAGGQSANFTPVFLQFLDCVHQVQYQFPTEFEFNDYYLRFLAYHHVSNRFRTFLLDSDYERIE 1379          
BLAST of Myotubularin-related protein vs. Ensembl Yeast
Match: YMR1 (Phosphatidylinositol 3-phosphate (PI3P) phosphatase; involved in various protein sorting pathways, including CVT targeting and endosome to vacuole transport; has similarity to the conserved myotubularin dual specificity phosphatase family [Source:SGD;Acc:S000003871])

HSP 1 Score: 140.198 bits (352), Expect = 8.734e-36
Identity = 97/296 (32.77%), Postives = 149/296 (50.34%), Query Frame = 2
Query:  488 YEVLKHEFQRLKFDPNE----WVISPKNEKFEFCETYPRYHIVLKEFEE-FIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYL-KRVCALSNSDT--NKLLIFDARPSADAIRNLKNGGGSENNGFYD-------MGKHE----------FLNIINMFQVKDI---FTEFIDCCESEKSDIAL--------KNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEI 1267
            Y+ +K EF+R   D  +    W +S  NE +EFC TYP    V +   +  ++  S FR ++R   + YH+      I+R SQP+ G    RSI +E  + +   +  N D    K +I DARP  +A+  +  GGG+EN   Y+       MG  +          FL I N+  V +     TE I  C+    ++ L        K S W++  + IL +   + K I  + S+VL+HC+DGWDRT Q+ +L ++ +DPFYR+  GF ILVE++W   GH+F +R      +I
Sbjct:  159 YDPIK-EFRRQGLDSKDETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQDEKLVWESFNSFCNKDIRRTKHVIVDARPRTNALAQMALGGGTENMDNYNFFLADNNMGVDKSLKLPTVTRLFLGIDNIHIVSNTAAYMTEVI--CQGGDLNLPLEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSDI 451          

HSP 2 Score: 48.1358 bits (113), Expect = 2.827e-6
Identity = 28/81 (34.57%), Postives = 46/81 (56.79%), Query Frame = 2
Query: 1280 SPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNF 1516
            SPVF Q+LDC++Q++++ P+ F+FN ++L +L + +       F  NS KE+ +     +   VW Y  +S  K   N NF
Sbjct:  520 SPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYF-RSRRKQFINPNF 599          
BLAST of Myotubularin-related protein vs. Ensembl Nematostella
Match: EDO44480 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVM7])

HSP 1 Score: 215.698 bits (548), Expect = 1.254e-62
Identity = 126/372 (33.87%), Postives = 207/372 (55.65%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGE-SKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQ-EITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFN--SMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNP--STEIVEIDYSVKNLLIWKEIYI 1588
            EF+RL    + W ++  NEK+E  +TYP    V     +E I+ ++ FR + R   + + +  N + I R SQP  G  ++N+   +E Y + +   +N   +KLLIFDARP  +A+ N   GGG E    Y   +  FL+I N+  +++   +  D C     D      L+N+KW+  I  I+  +++IA  +   R+SV++HC+DGWDRTPQLTALA L+MDP+YR++ GF++L+E+EW   GHKF QR     +     + SPVFLQ++DC++Q+  +FP  F+FN  +L  +   +   +   F +N  S +E+ + +     +W+Y++ S M   +N  + P     ++    S++ L +W   YI
Sbjct:  175 EFERLGLPTDCWYVTRINEKYELSDTYPAVVGVPSSVSDEDIKKVAVFRSRNRLPVLCWLHPTNNASITRASQPNRGLLARNKD--DEKYFQAILE-ANPQCHKLLIFDARPRINAVANQAKGGGYETEENYQNTEVIFLDIANIHVMRESLRKLKDICFPNIDDTHWLTNLENTKWLDHIKMIMAGAVRIADAVDRCRTSVVVHCSDGWDRTPQLTALAMLLMDPYYRTIIGFEVLIEKEWLSFGHKFNQRYGHGDKNHADDQRSPVFLQFIDCVWQVTRQFPCAFEFNETFLITILDHLYSCMFGTFLYNSESQREKEDVKTRTTSLWSYINTS-MMEFKNPLYAPYLHQHVLFPVPSLRRLELWTRYYI 542          
BLAST of Myotubularin-related protein vs. Ensembl Nematostella
Match: EDO34710 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNP0])

HSP 1 Score: 214.542 bits (545), Expect = 1.032e-61
Identity = 126/376 (33.51%), Postives = 208/376 (55.32%), Query Frame = 2
Query:  497 LKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIF--DARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCC-ESEKSDIA-----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKER--IENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEI--DYSVKNLLIWKEIY 1585
            +K ++ R+    + W  +  N+ +E C+TYP    V K   +E +   S FR + R   + +++   ++ + RCSQP+ G  K R   +E  ++   AL NS+ N   I+  D RP  +A+ N   G G E+  FY+  K +F+ I N+  ++    + ++   ES K+        L+ S W++ I +IL  S+ IAK + ++++SVL+HC+DGWDRT Q  +LA +I+DP+YR++HGFQ+L+E+EW   GHKF  RC    Q   +EFSPVFLQ+L+ I+Q++ +FP  FQFN ++L  L   +       F  N  KER  +   K  + +W Y+ Q ++    N  +   T+   +  D S + +  W+ +Y
Sbjct:  133 IKSDYTRMGVPSDLWTATQLNKDYELCDTYPNILYVPKSATKEVLVGSSRFRSRGRLPVLSFYHKSTQAAVCRCSQPL-GGFKGRCPEDEQMIQ---ALLNSNPNSKFIYIVDTRPRLNALANRAAGKGYESEDFYENVKFQFVGIENIHVMRQSLFKMLEVVGESPKTPAGAFYSGLEASNWLKHIKNILDTSVFIAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLL-QSDQKEFSPVFLQFLESIWQLLQQFPFSFQFNERFLLTLHDHVYSCQFGTFLGNCQKERRDLGLPKRTYSLWGYMWQ-NISDYANPLYREVTQDDALWPDTSPQAIRFWRAMY 502          
BLAST of Myotubularin-related protein vs. Ensembl Nematostella
Match: EDO39920 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8S7])

HSP 1 Score: 199.904 bits (507), Expect = 2.626e-57
Identity = 115/379 (30.34%), Postives = 179/379 (47.23%), Query Frame = 2
Query:  506 EFQRLKFDPN---EWVISPKNEKFEFCETYPRYHIVLKEFEEF-IQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSD------------------------------------------TNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA-----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKY----LHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYL 1477
            E  R+ F+      W IS  N  FE C TYPR H++     +  +  +++FR   RF S+V+ +  N +VI RCSQP +G    RS  +E  L+ +     SD                                            ++LI DAR    A  N   GGG E   +Y   +  F+N+ N+  ++  F      C S   D+      ++ + W+  IS ++ +++ I   +  D   V++HC+DGWDRT Q+ ALA+L++DPFYR++ GF+IL+++EW Q GH+F  RC         E  PVFLQWLDC+ Q+  +FP+ F+F+  Y    LH  + C+      N +     + I  +     VW+Y+
Sbjct:  157 EVHRMGFETGVDSPWRISDANSSFEVCRTYPRLHVIPSSISDSDLAKVASFRCSGRFPSIVWRHMTNGAVIARCSQPQVGWLGWRSAEDELLLQAIGQACTSDRYPSVAKLLNGITVNGINKKHDMGDVLNGPADMSEDGPIARNPKQVLIVDARSYTAAYANRGKGGGFEYTEYYPNCEVMFMNLANIHGIRRSFHSLRALC-SGSYDVPNWWSLIEKTNWLHHISMLIKSAVTIVHAVHTDGRPVVVHCSDGWDRTTQIVALAELLLDPFYRTIEGFKILIDREWLQFGHRFADRCGHGSDIDENERCPVFLQWLDCVHQLQKQFPSSFEFSETYLIKLLHHTYSCLFGTFLGNNEHGRHTDAI--KARTLSVWSYI 532          
BLAST of Myotubularin-related protein vs. Ensembl Nematostella
Match: EDO33774 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR96])

HSP 1 Score: 150.984 bits (380), Expect = 1.457e-39
Identity = 99/372 (26.61%), Postives = 183/372 (49.19%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDI-----ALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEIT--REFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKER--IENQKEIFDVWTYLSQSD-MKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            +F ++      W IS  N  +E C +YP   IV L   ++ ++  + FR   RF  + Y +   +SV++R  +P+ G   N+   E+   +++   +     K +I D R +   + +   GGG E    Y   K    NI     + D   + ++ C  +   +      L++  W+  I  +L  +  +A C+  D   VL+H   G D T Q+T+L+++I+DP  R++ GFQ LV++EW + GH F  RC       T  +   PVFL +LDC++QI  +FP  F+F+  +L  LF          F  N+ K R  ++ +++   +W+YL+Q + ++ + N  +  +  ++    + ++L++W  +Y+
Sbjct:  133 DFAKVCSSTQSWRISHVNINYEVCASYPTSVIVPLGVSDDELKASAQFRHGARFPVLCYFHKATQSVLMRSGEPLCGSMSNKRCKED---EKLVNSALGSMKKGMIVDTRSTPAVMNSRSKGGGLEPESNYPQWKRSNHNIEKHTVLIDSVCKLMEACFDQNLSMNAYLSRLESCGWMDQIQAVLGTACYVAHCLHTDGIPVLVHDGAGLDATLQVTSLSQVILDPDCRTVRGFQSLVDREWIRGGHPFSNRCTRVGFSSTKYKGQGPVFLLFLDCVWQIYQQFPCSFEFHDSFLICLFEHAYYSQFGTFLCNNEKNRVTVKLKEKTISLWSYLNQDEILEDMLNPMYERNESVLWPSVAPQSLVLWPGLYL 501          
BLAST of Myotubularin-related protein vs. Ensembl Nematostella
Match: EDO48708 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIH6])

HSP 1 Score: 131.724 bits (330), Expect = 3.236e-35
Identity = 80/231 (34.63%), Postives = 138/231 (59.74%), Query Frame = 2
Query:  914 FLNIINMFQVKDIFTEFIDCCES---EKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRS-SVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIEN--QKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYI 1588
            FL+I N+  V+D        CES   +K    L++++W+  I+ IL  +  IA+ +  D+  S L+HC+DGWDRT QLT LA+L++DP+YR+  GFQ+L+E+EW   GH+F  R          + SP+FLQ+LDC++Q+  +FP+ FQF + YL +L   +N     NF +N+++ER      +    +W++L+ +   +  N+ + P+  +V +  S++ L +W + ++
Sbjct:    8 FLDIPNIHAVRDSLDRLQAVCESSSQKKWLSHLESTQWLAYIAAILKGATTIARFV--DKGVSTLVHCSDGWDRTSQLTLLAQLLLDPYYRTFTGFQVLIEKEWISFGHRFRDRLGH--PTCPSQRSPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLADHVNSQWFGNFLYNNVQERHHAFITRTTVSLWSHLN-AVKDNYTNSIYQPTETLVPVS-SLRRLQLWSDYFL 232          
BLAST of Myotubularin-related protein vs. Ensembl Medaka
Match: mtmr2 (myotubularin related protein 2 [Source:NCBI gene;Acc:101157315])

HSP 1 Score: 213.386 bits (542), Expect = 1.452e-61
Identity = 122/378 (32.28%), Postives = 216/378 (57.14%), Query Frame = 2
Query:  488 YEVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEIT-REFSPVFLQWLDCIFQIVSKFPNQFQFNSKY----LHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNF-NPSTEIVEIDYSVKNLLIWKEIYI 1588
            Y+ L  E++R       W I+  N+ +E C+TYP   +V     ++ ++ ++ FR K R   + + + E+++ + RCSQPM G +  R   +E YL+ +   +N+ ++KL IFDARP+  A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       D      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+LA L++D +YR++ GF+IL+E+EW   GH+F+QR     +  T  E SPVF+Q++DC++Q+  +FP+ F+FN  +    L  LF C+      N +   +KE +   K+   +W+Y++ S ++   N  + N S  ++    S+ +L +W   YI
Sbjct:  154 YDALA-EYKRQGIPNESWRITKINDHYELCDTYPASLVVPVNIPDDELKKVAAFRGKGRIPVLSWIHPESQATVTRCSQPMAGVNGKRCKEDEKYLQAIMD-ANAQSHKLFIFDARPNVSALANKMKGGGVESEDAYQNAELVFLDIHNIHVMRESLRKVKEAIYPNIDDAHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTTQLTSLAMLMLDGYYRTIRGFEILIEKEWLSFGHRFQQRIGHGDKNYTDAERSPVFVQFVDCVWQLTRQFPSAFEFNEYFLITILEHLFSCLFGTFLCNCEQQRLKEEVP--KKTVSLWSYIN-SQLEEFTNPFYVNYSNHVLFPVVSLHHLELWVSYYI 526          
BLAST of Myotubularin-related protein vs. Ensembl Medaka
Match: mtmr2 (myotubularin related protein 2 [Source:NCBI gene;Acc:101157315])

HSP 1 Score: 213.386 bits (542), Expect = 3.737e-61
Identity = 122/378 (32.28%), Postives = 216/378 (57.14%), Query Frame = 2
Query:  488 YEVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIA----LKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEIT-REFSPVFLQWLDCIFQIVSKFPNQFQFNSKY----LHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNF-NPSTEIVEIDYSVKNLLIWKEIYI 1588
            Y+ L  E++R       W I+  N+ +E C+TYP   +V     ++ ++ ++ FR K R   + + + E+++ + RCSQPM G +  R   +E YL+ +   +N+ ++KL IFDARP+  A+ N   GGG E+   Y   +  FL+I N+  +++   +  +       D      L+++ W++ I  IL  +++IA  ++  ++SV++HC+DGWDRT QLT+LA L++D +YR++ GF+IL+E+EW   GH+F+QR     +  T  E SPVF+Q++DC++Q+  +FP+ F+FN  +    L  LF C+      N +   +KE +   K+   +W+Y++ S ++   N  + N S  ++    S+ +L +W   YI
Sbjct:  205 YDALA-EYKRQGIPNESWRITKINDHYELCDTYPASLVVPVNIPDDELKKVAAFRGKGRIPVLSWIHPESQATVTRCSQPMAGVNGKRCKEDEKYLQAIMD-ANAQSHKLFIFDARPNVSALANKMKGGGVESEDAYQNAELVFLDIHNIHVMRESLRKVKEAIYPNIDDAHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTTQLTSLAMLMLDGYYRTIRGFEILIEKEWLSFGHRFQQRIGHGDKNYTDAERSPVFVQFVDCVWQLTRQFPSAFEFNEYFLITILEHLFSCLFGTFLCNCEQQRLKEEVP--KKTVSLWSYIN-SQLEEFTNPFYVNYSNHVLFPVVSLHHLELWVSYYI 577          
BLAST of Myotubularin-related protein vs. Ensembl Medaka
Match: mtm1 (myotubularin 1 [Source:NCBI gene;Acc:101168528])

HSP 1 Score: 209.92 bits (533), Expect = 3.264e-60
Identity = 124/370 (33.51%), Postives = 209/370 (56.49%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIV-LKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFID----CCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEIT-REFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFN--SMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNP-STEIVEIDYSVKNLLIWKEIYI 1588
            EF+R     N+W I+  N+ +E C+TYP    V  K  EE ++ ++ FR + R   + + + ENK+VI+RCSQP++G S  R+  +E YL  +     +DT KL I+DARPS +A+ N   GGG E +  Y   +  FL+I N+  +++   +  D      E      +L+++ W++ I  +L  +I++A  +     SV++HC+DGWDRT QLT+LA L++D  +R+L G Q+L+E+EW   GHKF  R     +  T ++ SP+F+Q++DC++Q+  +FP  F+FN   L  +   +       F +N  S +++ E + +   +W+ L  S M+   N  + P S  ++    S+++L +W   YI
Sbjct:  169 EFRRQGLPNNKWRITFINKNYELCDTYPTVLAVPFKSTEEDLKRVATFRSRGRIPVLSWIHRENKAVIVRCSQPLVGMSGKRNKDDERYLDLI--REANDTTKLTIYDARPSVNAVANKATGGGYEGDE-YQNAELVFLDIQNIHVMRESLKKLKDIVYPTVEESHWLSSLESTHWLEHIKLVLSGAIQVADKVS-GGHSVVVHCSDGWDRTAQLTSLAMLMLDSHFRTLRGLQVLIEKEWISFGHKFASRIGHGDKNHTDQDRSPIFVQFIDCVWQMTKQFPTAFEFNENLLLTILDHLYSCRFGTFLYNCESARDQNEVRTKTLSLWS-LVNSKMEIYLNPFYTPESGRVLYPVASMRHLELWVTYYI 533          
BLAST of Myotubularin-related protein vs. Ensembl Medaka
Match: mtmr1a (myotubularin-related protein 2 [Source:NCBI gene;Acc:101157977])

HSP 1 Score: 209.92 bits (533), Expect = 8.586e-60
Identity = 119/340 (35.00%), Postives = 198/340 (58.24%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMF-------QVKDIFTEFIDCCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQE-ITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERI--ENQKEIFDVWTYL-SQSD 1489
            E++R       W IS  N  +E C+TYP   ++     EE ++ +++FR + R   + + + E+++ I+RCSQP++G S +R   E+  L +V   +N+ ++KL IFDAR S+ AI N    GG E+  FY   +  FL I N+        ++KD+    ID         A+  + W++ I  +L  + K+A  ++  +SSV++HC+DGWDRT QLT+L+ L++D +YR+L GFQ+LVE+EW   GHKF  R     ++    E SP+F+Q++DC++Q+  +FP+ F+FN  +L  +   +   +   F  NS +ER+  E Q +   +W+Y+ SQS+
Sbjct:  221 EYRRQGLPNESWTISRVNSIYELCDTYPSTLVIPTNITEEDLKRVASFRARHRVPVLSWIHPESQATIVRCSQPLVGPS-DRRCKEDERLLQVIMDANAQSHKLTIFDARQSSVAISNKAKDGGFESESFYANAELIFLEIPNIHVIRESQRKLKDMLYPTIDEAHWHS---AIDQTHWLEYIRLLLAGAAKVAHKVESGKSSVVVHCSDGWDRTAQLTSLSMLMLDGYYRTLTGFQVLVEKEWISFGHKFCARVGHGDKDHADSERSPLFVQFVDCVWQMTRQFPSAFEFNELFLITVLDYLYSCLFGTFLCNSEQERVAQEVQTKTASLWSYINSQSE 556          
BLAST of Myotubularin-related protein vs. Ensembl Medaka
Match: mtmr1a (myotubularin-related protein 2 [Source:NCBI gene;Acc:101157977])

HSP 1 Score: 209.149 bits (531), Expect = 1.223e-59
Identity = 120/333 (36.04%), Postives = 197/333 (59.16%), Query Frame = 2
Query:  530 PNE-WVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMF-------QVKDIFTEFIDCCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQE-ITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERI--ENQKEIFDVWTYL-SQSD 1489
            PNE W IS  N  +E C+TYP   ++     EE ++ +++FR + R   + + + E+++ I+RCSQP++G S +R   E+  L +V   +N+ ++KL IFDAR S+ AI N    GG E+  FY   +  FL I N+        ++KD+    ID         A+  + W++ I  +L  + K+A  ++  +SSV++HC+DGWDRT QLT+L+ L++D +YR+L GFQ+LVE+EW   GHKF  R     ++    E SP+F+Q++DC++Q+  +FP+ F+FN  +L  +   +   +   F  NS +ER+  E Q +   +W+Y+ SQS+
Sbjct:  221 PNESWTISRVNSIYELCDTYPSTLVIPTNITEEDLKRVASFRARHRVPVLSWIHPESQATIVRCSQPLVGPS-DRRCKEDERLLQVIMDANAQSHKLTIFDARQSSVAISNKAKDGGFESESFYANAELIFLEIPNIHVIRESQRKLKDMLYPTIDEAHWHS---AIDQTHWLEYIRLLLAGAAKVAHKVESGKSSVVVHCSDGWDRTAQLTSLSMLMLDGYYRTLTGFQVLVEKEWISFGHKFCARVGHGDKDHADSERSPLFVQFVDCVWQMTRQFPSAFEFNELFLITVLDYLYSCLFGTFLCNSEQERVAQEVQTKTASLWSYINSQSE 549          
BLAST of Myotubularin-related protein vs. Planmine SMEST
Match: SMESG000069349.1 (SMESG000069349.1)

HSP 1 Score: 671.389 bits (1731), Expect = 0.000e+0
Identity = 333/375 (88.80%), Postives = 335/375 (89.33%), Query Frame = 2
Query:  470 KPTDSYYEVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYIMQ 1594
            KPTDSYYEVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEFEEFIQDLSNFRRKQRFLSVVYHNSENKS+                               S T       + PSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYIMQ
Sbjct:  126 KPTDSYYEVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEFEEFIQDLSNFRRKQRFLSVVYHNSENKSL-------------------------------SKT-------SLPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYIMQ 462          

HSP 2 Score: 216.468 bits (550), Expect = 0.000e+0
Identity = 109/122 (89.34%), Postives = 110/122 (90.16%), Query Frame = 3
Query:  114 FSVPYRIKI*SIFRWENAMLLPGEKVEANLNMNIHRLILTNHRIINVGSQNHKNFNISLGLVEKFQVEKNILKIKLRTGSSITINLDKCENFEKVFEKALESYIPFNESLLFKNSHCFENQP 479
            F  P   K      WENAMLLPGEKVEANLNMNIHRLILTNHRIINVGSQNHKNFNISLGLVEKFQVEKNILKIKLRTGSSITINLDKCENFEKVFEKALESYIPFNESLLFKNSHCFE +P
Sbjct:    6 FQSPIESKFDRFSEWENAMLLPGEKVEANLNMNIHRLILTNHRIINVGSQNHKNFNISLGLVEKFQVEKNILKIKLRTGSSITINLDKCENFEKVFEKALESYIPFNESLLFKNSHCFERKP 127          
BLAST of Myotubularin-related protein vs. Planmine SMEST
Match: SMESG000069357.1 (SMESG000069357.1)

HSP 1 Score: 278.1 bits (710), Expect = 5.492e-85
Identity = 140/376 (37.23%), Postives = 224/376 (59.57%), Query Frame = 2
Query:  491 EVLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEFEE-FIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYL-----KRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDI---ALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTYLSQSDMKHLQNTNFNP--STEIVEIDYSVKNLLIWKEIY 1585
            E++  EF R++F  + W IS  NE+F+ C TYP+YHIV K F +  I++++ FR K RF+SV Y + E  +V++R  QP+ G S  R+  +E Y       R C +  ++  +L I+DAR    A  N   GGG E+   Y +   EFLNI NM  V++ F  F        SD     +  S W+Q I  ++ ++ +I   + I + SVLIHC+DGWDRTPQL +L++++MDP+YR++ GF+IL+ +EW   GHKF +RCA WP + +RE+SP+F+QWLDC++Q++ +FP+ F FN  +L +L   +  G+     F +    I N  E   +W++L Q +M    N  ++P  + ++++  + + N+ +W  +Y
Sbjct:   50 EIITKEFDRMQFSGDFWRISSINEEFKICSTYPQYHIVPKSFPDNLIKEMAKFRSKGRFISVSYRSIEAGTVMLRSGQPLTGVSCWRNEADEKYFHVINDNRTCEVLETEGLQLKIYDARSYTSAQLNRVKGGGMESETNYSIKSLEFLNIPNMHAVRNSFESFTKALLENDSDNFYELIFKSNWLQLIRQLIKSASQITDTMCIKKISVLIHCSDGWDRTPQLVSLSQILMDPYYRTIEGFRILIYREWILFGHKFNERCALWPVDFSREYSPIFVQWLDCVYQLLQQFPDYFHFNETFLIKLAIHVYSGM-----FGTFNTVISNTTETCSLWSFLCQKEMHDFINPLYSPHKTFKLIKPKFQMSNIKLWNNLY 420          
BLAST of Myotubularin-related protein vs. Planmine SMEST
Match: SMESG000032817.1 (SMESG000032817.1)

HSP 1 Score: 254.603 bits (649), Expect = 5.050e-75
Identity = 139/379 (36.68%), Postives = 221/379 (58.31%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRV--CALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCE-----SEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMK---------HLQNTNFNPSTEIVEIDYSVKNLLIWKEIY 1585
            EF+R+KF    W I+  N+KF+ C +YP YHIV     +E I+ ++ FR  +RF SVV+ + +N +VIIRC+QP +G    R+  +E++ K V  C   N +  +LLI DAR  + A  N   GGG E + +Y   +  F+ + N+  V+  F    DC        E    +++NS W++ +S +L ++  IA+ +  D  SV+IHC+DGWDRTPQLT+L+++++D FYR++ GF++L+E+EW   GHKF  RC F      +E+SP+F+QWLDCI Q++ ++P  F+FN  +L +L   +  G+  NF FNS +ER  N        +W +LS+S+            +  TNF+   +++   Y+ K L  W  ++
Sbjct:  116 EFKRMKFSNKIWKITDVNKKFQVCNSYPPYHIVPCSISDEDIKAMAEFRGNKRFPSVVWRSQKNGAVIIRCAQPQVGLMFWRNSFDETFFKEVLKCLKCNGNKKRLLIIDARHYSTAQFNRIRGGGVEYSEYYGEAEIVFMQLENIHSVRSSF----DCISMFSMNGENWFTSIENSCWLKYLSKLLKSACDIARALNEDGRSVIIHCSDGWDRTPQLTSLSQILLDDFYRTIKGFKVLIEREWIHFGHKFSDRCGFNKSVDNKEWSPIFVQWLDCIHQLIRQYPCYFEFNETFLVKLALHVYSGLFGNFMFNSEEERQNNGVYSSTACIWNFLSESNEDIINPLFYKFSVAETNFDVYKKVIYPKYTTKFLFPWNRLF 490          
BLAST of Myotubularin-related protein vs. Planmine SMEST
Match: SMESG000032817.1 (SMESG000032817.1)

HSP 1 Score: 254.988 bits (650), Expect = 7.441e-75
Identity = 139/379 (36.68%), Postives = 221/379 (58.31%), Query Frame = 2
Query:  506 EFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRV--CALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCE-----SEKSDIALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMK---------HLQNTNFNPSTEIVEIDYSVKNLLIWKEIY 1585
            EF+R+KF    W I+  N+KF+ C +YP YHIV     +E I+ ++ FR  +RF SVV+ + +N +VIIRC+QP +G    R+  +E++ K V  C   N +  +LLI DAR  + A  N   GGG E + +Y   +  F+ + N+  V+  F    DC        E    +++NS W++ +S +L ++  IA+ +  D  SV+IHC+DGWDRTPQLT+L+++++D FYR++ GF++L+E+EW   GHKF  RC F      +E+SP+F+QWLDCI Q++ ++P  F+FN  +L +L   +  G+  NF FNS +ER  N        +W +LS+S+            +  TNF+   +++   Y+ K L  W  ++
Sbjct:  148 EFKRMKFSNKIWKITDVNKKFQVCNSYPPYHIVPCSISDEDIKAMAEFRGNKRFPSVVWRSQKNGAVIIRCAQPQVGLMFWRNSFDETFFKEVLKCLKCNGNKKRLLIIDARHYSTAQFNRIRGGGVEYSEYYGEAEIVFMQLENIHSVRSSF----DCISMFSMNGENWFTSIENSCWLKYLSKLLKSACDIARALNEDGRSVIIHCSDGWDRTPQLTSLSQILLDDFYRTIKGFKVLIEREWIHFGHKFSDRCGFNKSVDNKEWSPIFVQWLDCIHQLIRQYPCYFEFNETFLVKLALHVYSGLFGNFMFNSEEERQNNGVYSSTACIWNFLSESNEDIINPLFYKFSVAETNFDVYKKVIYPKYTTKFLFPWNRLF 522          
BLAST of Myotubularin-related protein vs. Planmine SMEST
Match: SMESG000072462.1 (SMESG000072462.1)

HSP 1 Score: 233.032 bits (593), Expect = 5.015e-69
Identity = 135/384 (35.16%), Postives = 213/384 (55.47%), Query Frame = 2
Query:  494 VLKHEFQRLKFDPNEWVISPKNEKFEFCETYPRYHIVLKEF-EEFIQDLSNFRRKQRFLSVVYHNSENKSVIIRCSQPMIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGGSENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDI----ALKNSKWIQSISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYRSLHGFQILVEQEWRQMGHKFEQRCAFWPQEIT--------REFSPVFLQWLDCIFQIVSKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQ--KEIFDVWTYLSQSDMKHLQNTNFNPSTE----IVEIDYSVKNLLIWKEIYI 1588
            VL  E+QR   + N W IS  N  FE CETYP    V K+  +E I +   FR K RF  + + + + K+ + R SQP  G +  R+  +E YLK +   +N+  N L I DARP  +A  N+  GGG E+   Y    ++FLNI N+  +++   +  D C  +  +     AL+ +KW+  I  IL  S+ +A+ I   RS VL+HC+DGWDRT Q+T+L +L++DP++R++ GFQ L+++EW  MGHK  QR     +E           E +P+FLQ++DC++QI  +F   F+FN ++L  L   +  G+  NF FNS ++R  N+   +    W +++ SD++  +N  F P+ E    ++   Y +  +  WK  Y+
Sbjct:  155 VLSDEYQRQLIESNNWRISKVNHNFEVCETYPDEVAVPKDVSDETITNACQFRTKNRFPVLCWIHPDTKATLTRSSQPATGLTWKRNESDERYLKSIKD-ANAYNNLLTIIDARPMINARANMARGGGIESQNIYTSISYDFLNIPNIHVMRESMRKLADLCYPKPDNSNWHKALEETKWLNYIRQILLGSLMVAEKINSQRS-VLVHCSDGWDRTAQITSLPQLMLDPYFRTIRGFQTLIDKEWLLMGHKISQRTGGLTEEFGSTSSTSQKSERAPIFLQFIDCVWQITQQFLAAFEFNEQFLIDLMDAVYSGLFGNFLFNSEQQRRTNEVYTKTLSFWDHVN-SDIEKYRNPLFTPADESGHRVLFPQYRLPCIRFWKSYYL 535          
The following BLAST results are available for this feature:
BLAST of Myotubularin-related protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MTMR22.435e-6332.16myotubularin related protein 2 [Source:HGNC Symbol... [more]
MTMR23.715e-6332.16myotubularin related protein 2 [Source:HGNC Symbol... [more]
MTMR23.715e-6332.16myotubularin related protein 2 [Source:HGNC Symbol... [more]
MTMR23.715e-6332.16myotubularin related protein 2 [Source:HGNC Symbol... [more]
MTMR21.282e-6232.16myotubularin related protein 2 [Source:HGNC Symbol... [more]
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BLAST of Myotubularin-related protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtm-12.078e-5834.21Myotubularin-related protein 1 [Source:UniProtKB/... [more]
mtm-61.911e-5329.44Myotubularin-related protein 6 [Source:UniProtKB/... [more]
mtm-61.957e-5329.71Myotubularin-related protein 6 [Source:UniProtKB/... [more]
mtm-65.255e-5329.71Myotubularin-related protein 6 [Source:UniProtKB/... [more]
mtm-65.255e-5329.71Myotubularin-related protein 6 [Source:UniProtKB/... [more]
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BLAST of Myotubularin-related protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtm2.640e-6332.72gene:FBgn0025742 transcript:FBtr0079223[more]
mtm2.640e-6332.72gene:FBgn0025742 transcript:FBtr0345290[more]
CG35301.152e-5933.95gene:FBgn0028497 transcript:FBtr0112940[more]
CG35302.310e-5933.95gene:FBgn0028497 transcript:FBtr0072028[more]
CG35301.056e-5833.95gene:FBgn0028497 transcript:FBtr0072029[more]
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BLAST of Myotubularin-related protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtmr65.725e-6229.95myotubularin related protein 6 [Source:ZFIN;Acc:ZD... [more]
mtm16.623e-6232.98myotubularin 1 [Source:ZFIN;Acc:ZDB-GENE-051113-12... [more]
mtmr23.271e-5931.49myotubularin related protein 2 [Source:NCBI gene;A... [more]
mtmr1b8.180e-5931.73myotubularin related protein 1b [Source:ZFIN;Acc:Z... [more]
mtmr1b1.095e-5831.73myotubularin related protein 1b [Source:ZFIN;Acc:Z... [more]
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BLAST of Myotubularin-related protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MTMR21.246e-6231.27myotubularin related protein 2 [Source:NCBI gene;A... [more]
MTMR21.804e-6231.18myotubularin related protein 2 [Source:NCBI gene;A... [more]
MTMR21.906e-6232.14myotubularin related protein 2 [Source:NCBI gene;A... [more]
MTMR21.924e-6232.14myotubularin related protein 2 [Source:NCBI gene;A... [more]
MTMR22.651e-6231.18myotubularin related protein 2 [Source:NCBI gene;A... [more]
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BLAST of Myotubularin-related protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mtm17.466e-6434.41X-linked myotubular myopathy gene 1 [Source:MGI Sy... [more]
Mtm17.466e-6434.41X-linked myotubular myopathy gene 1 [Source:MGI Sy... [more]
Mtm17.466e-6434.41X-linked myotubular myopathy gene 1 [Source:MGI Sy... [more]
Mtm17.466e-6434.41X-linked myotubular myopathy gene 1 [Source:MGI Sy... [more]
Mtmr22.073e-6331.89myotubularin related protein 2 [Source:MGI Symbol;... [more]
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BLAST of Myotubularin-related protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9Z2C5|MTM1_MOUSE5.222e-6334.41Myotubularin OS=Mus musculus OX=10090 GN=Mtm1 PE=1... [more]
sp|Q13614|MTMR2_HUMAN6.157e-6232.16Myotubularin-related protein 2 OS=Homo sapiens OX=... [more]
sp|Q13496|MTM1_HUMAN6.344e-6234.14Myotubularin OS=Homo sapiens OX=9606 GN=MTM1 PE=1 ... [more]
sp|Q9Z2D1|MTMR2_MOUSE6.616e-6231.89Myotubularin-related protein 2 OS=Mus musculus OX=... [more]
sp|Q6AXQ4|MTM1_RAT9.210e-6231.98Myotubularin OS=Rattus norvegicus OX=10116 GN=Mtm1... [more]
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BLAST of Myotubularin-related protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A068YD001.963e-6835.43Myotubularin protein 3 OS=Echinococcus multilocula... [more]
A0A0X3PVE44.659e-6835.19Myotubularin-related protein 3 OS=Schistocephalus ... [more]
A0A564YS644.849e-6834.97Myotubularin phosphatase domain-containing protein... [more]
A0A0R3SYK05.637e-6834.97Myotubularin phosphatase domain-containing protein... [more]
A0A0R3VVR42.151e-6735.64Myotubularin phosphatase domain-containing protein... [more]
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BLAST of Myotubularin-related protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtmr1b9.827e-6332.80myotubularin-related protein 1-like [Source:NCBI g... [more]
mtmr1b1.631e-6232.80myotubularin-related protein 1-like [Source:NCBI g... [more]
mtmr68.333e-5929.95myotubularin related protein 6 [Source:NCBI gene;A... [more]
mtm11.205e-5831.41myotubularin 1 [Source:ZFIN;Acc:ZDB-GENE-051113-12... [more]
mtmr21.707e-5830.62myotubularin related protein 2 [Source:NCBI gene;A... [more]
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BLAST of Myotubularin-related protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtm11.798e-6932.35myotubularin 1 [Source:ZFIN;Acc:ZDB-GENE-051113-12... [more]
mtmr91.842e-4829.53myotubularin related protein 9 [Source:ZFIN;Acc:ZD... [more]
ENSPMAT00000002170.11.004e-3141.67pep scaffold:Pmarinus_7.0:GL484749:1247:6808:1 gen... [more]
sbf12.588e-2441.18SET binding factor 1 [Source:ZFIN;Acc:ZDB-GENE-040... [more]
ENSPMAT00000010382.18.972e-2334.84pep scaffold:Pmarinus_7.0:GL482471:369374:413667:1... [more]
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BLAST of Myotubularin-related protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
YMR18.734e-3632.77Phosphatidylinositol 3-phosphate (PI3P) phosphatas... [more]
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BLAST of Myotubularin-related protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO444801.254e-6233.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO347101.032e-6133.51Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO399202.626e-5730.34Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO337741.457e-3926.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO487083.236e-3534.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Myotubularin-related protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtmr21.452e-6132.28myotubularin related protein 2 [Source:NCBI gene;A... [more]
mtmr23.737e-6132.28myotubularin related protein 2 [Source:NCBI gene;A... [more]
mtm13.264e-6033.51myotubularin 1 [Source:NCBI gene;Acc:101168528][more]
mtmr1a8.586e-6035.00myotubularin-related protein 2 [Source:NCBI gene;A... [more]
mtmr1a1.223e-5936.04myotubularin-related protein 2 [Source:NCBI gene;A... [more]
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BLAST of Myotubularin-related protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000069349.10.000e+088.80SMESG000069349.1[more]
SMESG000069357.15.492e-8537.23SMESG000069357.1[more]
SMESG000032817.15.050e-7536.68SMESG000032817.1[more]
SMESG000032817.17.441e-7536.68SMESG000032817.1[more]
SMESG000072462.15.015e-6935.16SMESG000072462.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004793 ID=SMED30004793|Name=Myotubularin-related protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1609bp
TAAAGATTGATTGAAAGATTTAAAGAAATTATTCATTTGTTTTAATTCTT
TCAAAAAGCTAATTTGTATAATAATTTGCAAATAATTCCAGAATTATTGA
TGGCACCTATAGATTTTCAGTCCCCTATCGAATCAAAATTTGATCGATTT
TCAGATGGGAAAATGCCATGTTATTGCCAGGAGAAAAAGTGGAAGCAAAC
TTGAACATGAACATTCACCGATTGATTCTAACCAATCACAGAATTATAAA
TGTCGGTTCACAGAATCATAAAAACTTTAACATTTCATTGGGTTTAGTTG
AAAAATTTCAAGTGGAAAAAAATATTTTAAAAATAAAATTAAGAACAGGA
AGCTCTATCACAATTAATTTAGATAAATGTGAAAATTTTGAGAAGGTATT
CGAAAAAGCTCTAGAGTCATATATTCCATTTAATGAAAGTTTATTATTCA
AGAATAGTCATTGTTTTGAAAACCAACCGATTCTTATTATGAGGTTCTAA
AACACGAATTTCAAAGACTTAAATTTGATCCAAACGAATGGGTGATATCT
CCAAAAAATGAGAAATTCGAGTTTTGCGAAACATATCCACGTTATCATAT
TGTATTAAAAGAGTTCGAAGAATTCATACAAGACTTGTCAAACTTTAGAC
GAAAGCAAAGATTTCTATCTGTGGTTTATCATAATTCCGAAAATAAATCT
GTAATTATTCGCTGCTCTCAGCCAATGATTGGCGAGTCGAAGAATCGATC
AATCATTGAAGAGAGTTATCTAAAACGAGTTTGTGCGTTATCAAATAGTG
ATACCAATAAACTATTGATTTTCGATGCCAGACCATCTGCTGATGCAATA
AGAAATCTAAAAAATGGCGGTGGCAGTGAAAATAATGGATTTTATGACAT
GGGAAAACATGAATTTTTGAATATCATTAACATGTTTCAAGTTAAAGATA
TTTTTACTGAGTTTATAGATTGTTGTGAAAGTGAGAAAAGTGATATTGCA
TTGAAAAACTCTAAATGGATTCAATCCATCAGTCACATTTTATACAATTC
AATCAAAATAGCGAAATGCATTAAAATTGACCGAAGTTCCGTGTTAATTC
ATTGTACAGATGGTTGGGATAGAACTCCACAGCTTACTGCGTTGGCAAAA
TTGATTATGGATCCATTTTATCGATCTTTACACGGCTTTCAAATTTTAGT
TGAACAAGAATGGCGTCAGATGGGTCACAAATTTGAACAAAGGTGCGCAT
TTTGGCCACAAGAAATAACAAGAGAATTTTCGCCCGTATTTCTACAATGG
CTCGATTGTATTTTCCAGATAGTTTCTAAGTTTCCAAATCAATTTCAATT
CAATAGCAAATATCTACATCAATTATTTTTTTGTATCAATGATGGAGTGA
ATGAAAACTTTCAATTTAATTCTATGAAAGAAAGAATTGAAAATCAAAAA
GAAATTTTCGACGTTTGGACATATTTGTCGCAATCAGACATGAAGCACTT
ACAGAACACAAATTTTAATCCATCAACAGAAATTGTAGAAATCGATTATT
CCGTAAAAAATCTACTAATCTGGAAGGAGATTTATATTATGCAATAAATA
CATATCGAG
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protein sequence of SMED30004793-orf-1

>SMED30004793-orf-1 ID=SMED30004793-orf-1|Name=SMED30004793-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=291bp
MIGESKNRSIIEESYLKRVCALSNSDTNKLLIFDARPSADAIRNLKNGGG
SENNGFYDMGKHEFLNIINMFQVKDIFTEFIDCCESEKSDIALKNSKWIQ
SISHILYNSIKIAKCIKIDRSSVLIHCTDGWDRTPQLTALAKLIMDPFYR
SLHGFQILVEQEWRQMGHKFEQRCAFWPQEITREFSPVFLQWLDCIFQIV
SKFPNQFQFNSKYLHQLFFCINDGVNENFQFNSMKERIENQKEIFDVWTY
LSQSDMKHLQNTNFNPSTEIVEIDYSVKNLLIWKEIYIMQ*
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protein sequence of SMED30004793-orf-2

>SMED30004793-orf-2 ID=SMED30004793-orf-2|Name=SMED30004793-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=111bp
MLLPGEKVEANLNMNIHRLILTNHRIINVGSQNHKNFNISLGLVEKFQVE
KNILKIKLRTGSSITINLDKCENFEKVFEKALESYIPFNESLLFKNSHCF
ENQPILIMRF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000106ciliated epithelial cell
Vocabulary: INTERPRO
TermDefinition
IPR030564Myotubularin_fam
IPR010569Myotubularin-like_Pase_dom
IPR029021Prot-tyrosine_phosphatase-like
IPR016130Tyr_Pase_AS
Vocabulary: molecular function
TermDefinition
GO:0004725protein tyrosine phosphatase activity
GO:0016791phosphatase activity
Vocabulary: biological process
TermDefinition
GO:0016311dephosphorylation
GO:0035335peptidyl-tyrosine dephosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR010569Myotubularin-like phosphatase domainPFAMPF06602Myotub-relatedcoord: 2..237
e-value: 3.9E-73
score: 246.4
IPR010569Myotubularin-like phosphatase domainPROSITEPS51339PPASE_MYOTUBULARINcoord: 1..287
score: 51.54
IPR030564Myotubularin familyPANTHERPTHR10807MYOTUBULARIN-RELATEDcoord: 5..288
IPR016130Protein-tyrosine phosphatase, active sitePROSITEPS00383TYR_PHOSPHATASE_1coord: 125..135
NoneNo IPR availableCDDcd14507PTP-MTM-likecoord: 1..198
e-value: 1.78241E-70
score: 215.489
IPR029021Protein-tyrosine phosphatase-likeSUPERFAMILYSSF52799(Phosphotyrosine protein) phosphatases IIcoord: 3..287