TNF receptor-associated factor
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30004739 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 22
Homology
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF6 (TNF receptor associated factor 6 [Source:HGNC Symbol;Acc:HGNC:12036]) HSP 1 Score: 108.997 bits (271), Expect = 1.171e-24 Identity = 106/466 (22.75%), Postives = 199/466 (42.70%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQ---MSLVKTE---NIFLIESLEKRGDKS-------------GLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTL--IQDRRNDEISGQMKELQEKQEKVSE-NLDLLQNSNEV--VSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + A PCG R+C CI + + + CP N+ I + + D I L VKCP E C EL +E+H C+ + CP C +P ++ +N H+L D ++ E +E+ Q ++ V E I + E + D G + + L+ +++N +++ L +++L I D SG + E++ QE + + L++ +++ ++ + S VS LK +I + K+ EI AQ I++WKI N ++ +E I S ++ + GY++C+ + +P + + ++ + M+G YD L WP + + +++Q ++ E + + +++PT RN FG+ F+ L + L+Q I+ D + ++C V
Sbjct: 63 PLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK-CPVDNE------ILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQ----CQRP-FQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRM--LAQAVHSLSVIPD------SGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLE-------DKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTA-QRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHL-EALRQRTFIKDDTLLVRCEV 499
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF6 (TNF receptor associated factor 6 [Source:HGNC Symbol;Acc:HGNC:12036]) HSP 1 Score: 108.997 bits (271), Expect = 1.171e-24 Identity = 106/466 (22.75%), Postives = 199/466 (42.70%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQ---MSLVKTE---NIFLIESLEKRGDKS-------------GLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTL--IQDRRNDEISGQMKELQEKQEKVSE-NLDLLQNSNEV--VSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + A PCG R+C CI + + + CP N+ I + + D I L VKCP E C EL +E+H C+ + CP C +P ++ +N H+L D ++ E +E+ Q ++ V E I + E + D G + + L+ +++N +++ L +++L I D SG + E++ QE + + L++ +++ ++ + S VS LK +I + K+ EI AQ I++WKI N ++ +E I S ++ + GY++C+ + +P + + ++ + M+G YD L WP + + +++Q ++ E + + +++PT RN FG+ F+ L + L+Q I+ D + ++C V
Sbjct: 63 PLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK-CPVDNE------ILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQ----CQRP-FQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRM--LAQAVHSLSVIPD------SGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLE-------DKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTA-QRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHL-EALRQRTFIKDDTLLVRCEV 499
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 105.531 bits (262), Expect = 2.107e-23 Identity = 102/378 (26.98%), Postives = 173/378 (45.77%), Query Frame = 1
Query: 445 LTVKCPMETCEFMDEL-SMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEEL----SALVKDNAVKDIQ---IKDLNNKINTLIQDRRNDEISGQMKELQEK-QEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNV-------KIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+ V CP + C L S + HL +C C + GC Q ++ H + + H LL E+ N+L ++ L+ + S+ K ++I +SL + +E + KE L S ++ V D Q +K+L+ +I R+N E + MK E Q +V+E E V +++R L+ + D + V +L ++ + V + +WKI + + + A ++S P++ GY+MC V NG KG ++F +M+G YD +L WP K VT L++Q GS+ R + ++ + S +KKPT E N + G P F+ + +L+ I+ D IFIK
Sbjct: 200 VVVSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQ-QIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNE-SVEKNKSI---QSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPF---RQNWEEADSMKSSVESLQNRVTEL--------ESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ--GSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA-QTVLENGTYIKDDTIFIK 557
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 105.531 bits (262), Expect = 2.107e-23 Identity = 102/378 (26.98%), Postives = 173/378 (45.77%), Query Frame = 1
Query: 445 LTVKCPMETCEFMDEL-SMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEEL----SALVKDNAVKDIQ---IKDLNNKINTLIQDRRNDEISGQMKELQEK-QEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNV-------KIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+ V CP + C L S + HL +C C + GC Q ++ H + + H LL E+ N+L ++ L+ + S+ K ++I +SL + +E + KE L S ++ V D Q +K+L+ +I R+N E + MK E Q +V+E E V +++R L+ + D + V +L ++ + V + +WKI + + + A ++S P++ GY+MC V NG KG ++F +M+G YD +L WP K VT L++Q GS+ R + ++ + S +KKPT E N + G P F+ + +L+ I+ D IFIK
Sbjct: 200 VVVSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQ-QIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNE-SVEKNKSI---QSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPF---RQNWEEADSMKSSVESLQNRVTEL--------ESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ--GSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA-QTVLENGTYIKDDTIFIK 557
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 104.76 bits (260), Expect = 2.394e-23 Identity = 112/460 (24.35%), Postives = 202/460 (43.91%), Query Frame = 1
Query: 211 KLINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMET--CEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENI---FLIESLEKRGDKSGLEQSKLKEEL----SALVKDNAVKDIQ---IKDLNNKINTLIQDRRNDEISGQMKELQEK-QEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNV-------KIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
K + +++ C C ++ + CG R+C C+ L + C + I +D C R I L + C E+ C L + HLK+ C + E+ C +P+ ++ + + L + K ++ ++++ + Q+SL++ E++ I+SL + +E + KE L S ++ V D Q +K+L+ +I R+N E + MK E Q +V+E E V +++R L+ + D + V +L ++ + V + +WKI + + + A ++S P++ GY+MC V NG KG ++F +M+G YD +L WP K VT L++Q GS+ R + ++ + S +KKPT E N + G P F+ + +L+ I+ D IFIK
Sbjct: 42 KFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPK-CTACQE--SIVKDKVFKDNCCKREI----LALQIYCRNESRGCAEQLMLGHLLVHLKN------DCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPF---RQNWEEADSMKSSVESLQNRVTEL--------ESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ--GSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA-QTVLENGTYIKDDTIFIK 474
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-2 (TNF Receptor Associated Factor (TRAF) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N586]) HSP 1 Score: 74.3294 bits (181), Expect = 3.042e-14 Identity = 44/141 (31.21%), Postives = 69/141 (48.94%), Query Frame = 1
Query: 1132 VIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNG-LVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNVCLNKE 1551
V++ K ++ I+S P++ GY+M P G + + +F V+ +MKG +DDIL WP + DVTF +++ D E+ ++P RN +FGF F+ L K E IFI+ V L+KE
Sbjct: 171 VVKATKNKSHRSIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILSDDKKELLTKTIYVNEMPEIQEFLERPEGLRNGTFGFQNFLPLA---KVTEFAADGDIFIQIKVLLSKE 308
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80]) HSP 1 Score: 65.0846 bits (157), Expect = 4.737e-11 Identity = 50/179 (27.93%), Postives = 82/179 (45.81%), Query Frame = 1
Query: 1036 DMLKFVFTKKLIEITAQLNVKIF----VWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQM--CLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRS------ESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
DM F + I A+ ++F +WKI+ L + AK +T IFS P+ GY+M C C+ +G K +Y ++KG +D L WP + L++Q+ R + K + N K +P ERNA+FG F L L + ++ D+I+++ +V
Sbjct: 239 DMGSFNDRQTRILSAAETCTEMFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKS-ISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVNITYVIDPRKLKANEK--FLARPRGERNAAFGSQSFCSLAIL---QNYVKDDKIYVQIDV 411
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0334401) HSP 1 Score: 73.9442 bits (180), Expect = 1.095e-13 Identity = 48/168 (28.57%), Postives = 79/168 (47.02%), Query Frame = 1
Query: 1039 MLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
MLK +K I T L +WKI + S + A+ + ++ S P++ S+ GY++ + NG + VY V+ G YD +L WP +TF L Q S +E + + +++P+ E + FGFP FI +LL I+ D +F++ V
Sbjct: 308 MLKSAVSKLSINYTGTL-----LWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFIS-HELLHSRPFIKGDTVFLRVKV 469
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0077429) HSP 1 Score: 73.559 bits (179), Expect = 1.250e-13 Identity = 48/168 (28.57%), Postives = 79/168 (47.02%), Query Frame = 1
Query: 1039 MLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
MLK +K I T L +WKI + S + A+ + ++ S P++ S+ GY++ + NG + VY V+ G YD +L WP +TF L Q S +E + + +++P+ E + FGFP FI +LL I+ D +F++ V
Sbjct: 317 MLKSAVSKLSINYTGTL-----LWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFIS-HELLHSRPFIKGDTVFLRVKV 478
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0308606) HSP 1 Score: 51.9878 bits (123), Expect = 8.136e-7 Identity = 40/152 (26.32%), Postives = 76/152 (50.00%), Query Frame = 1
Query: 1102 FVWKIENLSKVIEGAKESN---NTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVY-FNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPT---TERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
+W+I++ SK +E +K+ + ++ +FS+ F GY + L + NG KG + NV+ G YD +L+WPC++ E+I +D + +++E Y K+ +K + + N F P+ + + +R D +FI+ V
Sbjct: 257 LIWRIKDYSKKLEESKQYDTILHSAMFSNKAF----GYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQA--EIIIRDQCTNV-ADAEDY---VKTIFVRKKSDDFIQSNQYFHIPHKV-----ITSRNYLRNDSMFIEVRV 393
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0074274) HSP 1 Score: 51.9878 bits (123), Expect = 8.136e-7 Identity = 40/152 (26.32%), Postives = 76/152 (50.00%), Query Frame = 1
Query: 1102 FVWKIENLSKVIEGAKESN---NTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVY-FNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPT---TERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
+W+I++ SK +E +K+ + ++ +FS+ F GY + L + NG KG + NV+ G YD +L+WPC++ E+I +D + +++E Y K+ +K + + N F P+ + + +R D +FI+ V
Sbjct: 257 LIWRIKDYSKKLEESKQYDTILHSAMFSNKAF----GYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQA--EIIIRDQCTNV-ADAEDY---VKTIFVRKKSDDFIQSNQYFHIPHKV-----ITSRNYLRNDSMFIEVRV 393
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0334036) HSP 1 Score: 51.9878 bits (123), Expect = 8.136e-7 Identity = 40/152 (26.32%), Postives = 76/152 (50.00%), Query Frame = 1
Query: 1102 FVWKIENLSKVIEGAKESN---NTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVY-FNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPT---TERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
+W+I++ SK +E +K+ + ++ +FS+ F GY + L + NG KG + NV+ G YD +L+WPC++ E+I +D + +++E Y K+ +K + + N F P+ + + +R D +FI+ V
Sbjct: 257 LIWRIKDYSKKLEESKQYDTILHSAMFSNKAF----GYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQA--EIIIRDQCTNV-ADAEDY---VKTIFVRKKSDDFIQSNQYFHIPHKV-----ITSRNYLRNDSMFIEVRV 393
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf3 (TNF receptor-associated factor 3 [Source:ZFIN;Acc:ZDB-GENE-040801-257]) HSP 1 Score: 110.538 bits (275), Expect = 2.998e-25 Identity = 94/373 (25.20%), Postives = 170/373 (45.58%), Query Frame = 1
Query: 445 LTVKCPMETCEFMDEL-SMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNV-------KIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
V CP C F L S + H DC + V C + GCS + Q E+ EH + + H +++ L ++E++K+++ E ++ SL R + + +++E+ L + + + + K+ + + R M+E E E++ + +S + V S +++L++ + D L V +L E+ +L V +WKI + + + A S ++S P++ GY+MC V NG KG ++F VM+G YD +L WP K VT L++Q G A + + ++ + S +++PT E N + G P F+ + +L+ I+ D IFIK V
Sbjct: 202 FPVACP-NHCSFSSILRSELSSHQHDCPKAQVTCSFIRYGCSYKGLNQ-EMREHESSFASEHLRMMAVRNTTLEAKVEDVKSEL----MERYKVLPSLSSRLAEVERQYEEMREKNRQLEQKLVSMQMLMSSHSEKLLEVEMELRELRPLRAMREEVETLRGSVESMRSMVSSLDSSCVNSASGSHTLASLEQQLTRHDDLMSVHDVRLAEMDLKLQVLETASFNGTLIWKIRDYKRRKQEAVVSKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLQWPFKQKVTLMLMDQ--GPARKHLGDAFKPDPSSSSFRRPTGEMNIASGCPLFVA-QTVLENGTYIKDDTIFIKVTV 565
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2a (Tnf receptor-associated factor 2a [Source:ZFIN;Acc:ZDB-GENE-071120-2]) HSP 1 Score: 101.293 bits (251), Expect = 2.593e-22 Identity = 91/374 (24.33%), Postives = 162/374 (43.32%), Query Frame = 1
Query: 505 EHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIF-LIESLE----KRGDKSGLEQS---------------KLKEELSAL-VKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKE-------LQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGS----AFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+H+K C + C + +GC V + ++++H S+ H LL+ ++ ++ +E L+ Q + + I L +SL K G G S L + L A ++Q+ K+ L RR E+ ++ L + E+ + ++ + + + ++ KV L+ ++ D+ K+ E++A +FVWKI + SK + A +FS ++ S+ GY+MCL + NG +G ++F VM+G D +L WP VT L++Q+N AFR + S +++P ++ N + G P F L L + IR D IFIK
Sbjct: 204 DHIKLCTKFRTPCRFHVVGCDM-TVEKEKIHDHEQACSYEHLNLLLHFIMGIKVNLESLQPQSLELASHKIHELHQSLRELELKMGQLCGAGASVQGACALPPPPPPAPTLGTSFTPLPTAVGAALELQLHSEKTKVVEL--SRRCQELELKVNTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIIDAFRP-------DISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIK 567
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 97.0561 bits (240), Expect = 5.526e-21 Identity = 84/348 (24.14%), Postives = 147/348 (42.24%), Query Frame = 1
Query: 499 MEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGS----AFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+EH K C + C + EIGC + V + EH H +L++ ++++R L+ + + E++ L G G E + + ++ L N + L N E+ E+ + ++ + + + + +S KV L+ ++ D+ + L E+ +F+WKI S+ + A +FS ++ S+ GY+MCL + NG +G ++F VMKG YD +L WP VT L++Q+N AFR + S +++P +E N + G P F L L + +R D IFIK
Sbjct: 213 FQEHTKSCAKSKSACQFREIGC-RAVVDNCKQQEHEQTSIMEHLRLMLALLSSMR-----LRAEGAGEWQEDVGL-------GLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVL-----NKEV-----------ERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRP-------DVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIK 524
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 97.0561 bits (240), Expect = 5.526e-21 Identity = 84/348 (24.14%), Postives = 147/348 (42.24%), Query Frame = 1
Query: 499 MEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGS----AFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+EH K C + C + EIGC + V + EH H +L++ ++++R L+ + + E++ L G G E + + ++ L N + L N E+ E+ + ++ + + + + +S KV L+ ++ D+ + L E+ +F+WKI S+ + A +FS ++ S+ GY+MCL + NG +G ++F VMKG YD +L WP VT L++Q+N AFR + S +++P +E N + G P F L L + +R D IFIK
Sbjct: 213 FQEHTKSCAKSKSACQFREIGC-RAVVDNCKQQEHEQTSIMEHLRLMLALLSSMR-----LRAEGAGEWQEDVGL-------GLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVL-----NKEV-----------ERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRP-------DVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIK 524
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 96.6709 bits (239), Expect = 7.744e-21 Identity = 84/348 (24.14%), Postives = 147/348 (42.24%), Query Frame = 1
Query: 499 MEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGS----AFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+EH K C + C + EIGC + V + EH H +L++ ++++R L+ + + E++ L G G E + + ++ L N + L N E+ E+ + ++ + + + + +S KV L+ ++ D+ + L E+ +F+WKI S+ + A +FS ++ S+ GY+MCL + NG +G ++F VMKG YD +L WP VT L++Q+N AFR + S +++P +E N + G P F L L + +R D IFIK
Sbjct: 226 FQEHTKSCAKSKSACQFREIGC-RAVVDNCKQQEHEQTSIMEHLRLMLALLSSMR-----LRAEGAGEWQEDVGL-------GLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVL-----NKEV-----------ERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRP-------DVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIK 537
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: egf (epidermal growth factor [Source:Xenbase;Acc:XB-GENE-951823]) HSP 1 Score: 104.76 bits (260), Expect = 2.914e-23 Identity = 105/494 (21.26%), Postives = 202/494 (40.89%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCD--------------------RKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLL-VEYVNNLRNEIEELKTQMSLVKTENIFL------------IESLEKRGDKSGLEQ----------SKLKEELSALVKDNAVKDIQIKDLNN---------KINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + A PCG R+C CI + + + CP N+ +L++ + D I L VKCP + C EL +E HL CD KF CP +I C +N L D H++ + YV + ++ QM + + + E +++ L++ L+ S++ + + DI D + +++ +ND + + + L+E E++ L + + + V+ LK +I D +L E+ +Q IF+W+I N + +++ +E I S ++ + GY++CL + +P+ + + ++ + M+G YD +L WP + + +++Q G A + + E + + +++PT RN FG+ F+ L+ LKQ + ++ D + ++C+V
Sbjct: 65 PLESKYECPICLMALREAVQTPCGHRFCKACILKSIRDAGHK-CPVDNE----SLME--NQLFPDNFAKREILSLRVKCPSQGCTETMELRHLERHLVRCDFAGVECSQCQSSFPKYSLQKHKFEECPRRQIFC------ENCALAMALEDKLNHDQTCPLAYVTCEYCQTNLIREQMPAHYSMDCTMAPIPCMYYEFGCTEKMQRNDLARHLQEFTQAHMRMMAQTLRSFSSSVTPTSHMPDISFCDPSQFEPAPPSVATVHSSHTPSQND-CTQETRNLRETIEQLEGRLVRQDHQIRELIAKMETQCTYVNELKHTIRSLD-------NRLGEMESQQCSGIFIWRINNFNSLLKNQEEERPVVIHSQGFYTGKPGYKLCLRLHLQLPSA-QRCANYISLFVHTMQGEYDSLLPWPLQGTIRLSILDQSEGVAMQDQEEVMDTKPELLAFQRPTVARNPKGFGYVTFMHLQ-ALKQRQYVKNDTLLVRCSV 535
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 103.219 bits (256), Expect = 8.308e-23 Identity = 124/528 (23.48%), Postives = 217/528 (41.10%), Query Frame = 1
Query: 169 NLEITWKIIKENNFK--LINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETD----------------------------QNYCPGSNKYC------GINLIDFDRDI-----------CIDRSINIRISQLTVKC------PMETCEFMDELSMMEEHLK-DCDRKFVGCPYSEIGCS-----KPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQI-----------KDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNE----VVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+L T + ++ +K + P++E C C+ ++ N CG R+C C+ L T Q +C + C G LI D C ++ I +S K P + C L M++H DC + CP+ CS + E ++ H + + H L+ E+ N L ++ L+ + S E I+ L + +E + KE+L ++N + IQ+ KDL+ +I L Q DE G + Q ++S+ + +N+ V+ + ++ + +S + D D L+F +++E TA N + +WKI + + + A ++S P++ GY+MC V NG KG ++F +M+G YD +L WP K V+ L++Q G + R + ++ + S +KKPT E N + G P F+ + +L+ I+ D IFIK
Sbjct: 21 SLATTIYVPEQGGYKERFLKPVEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKHEDVDCPSVVISCPHM---CSVKSLLRSEGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESS----EKNKSIQILHNQMCSFEIEIERHKEQL----RNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQT--GDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMD-LRF----QVLE-TASYN-GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQ--GPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA-QTVLENGTYIKDDTIFIK 525
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 102.449 bits (254), Expect = 1.478e-22 Identity = 98/384 (25.52%), Postives = 175/384 (45.57%), Query Frame = 1
Query: 427 NIRISQLTVKCPMETCEFMDEL-SMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQI-----------KDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNE----VVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
++ + + CP C L S + HL +C C + GC+ Q ++ H + + H L+ E+ N L ++ L+ + S E I+ L + +E + KE+L ++N + IQ+ KDL+ +I L Q DE G + Q ++S+ + +N+ V+ + ++ + +S + D D L+F +++E TA N + +WKI + + + A ++S P++ GY+MC V NG KG ++F +M+G YD +L WP K V+ L++Q G + R + ++ + S +KKPT E N + G P F+ + +L+ I+ D IFIK
Sbjct: 189 DVDCPSVVISCP-HMCSVKSLLRSELNAHLLECVNAPSTCSFKRYGCTFKGTNQ-QIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESS----EKNKSIQILHNQMCSFEIEIERHKEQL----RNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQT--GDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMD-LRF----QVLE-TASYN-GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQ--GPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA-QTVLENGTYIKDDTIFIK 550
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415]) HSP 1 Score: 92.0485 bits (227), Expect = 2.664e-19 Identity = 108/488 (22.13%), Postives = 187/488 (38.32%), Query Frame = 1
Query: 244 CLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNY-----CP------------------GSNKY-------CGINLIDFDRDI-----CIDRSINIRISQLTV-------------KCPMETCEFMDELSMMEEHLKDCDRKF-------VGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNG----SAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
C CK ++ A CG RYC C+ + + +N+ CP G Y C + +RD+ C +R +N R +L+ K PM TCE + E ++ F + C Y+ +GC++ V ++ EH H + +Y+ + R E +L +M SL +G + L K N + + LN ++ +E++ Q++ QEK E ++ KV L+ ++ +++ ++ E +F+WKI K + A +FS P++ ++ GY+MCL + NG + ++F VMKG D +L WP VT L++Q+N AFR + S +++P +E N + G P F ++ L + +R D IF+K
Sbjct: 37 CSDCKNLLRRPLQAQCGHRYCSHCLNKIIRWVARNWGGVPECPAVCERSDWTGALISVGHEGKCPYLLAPCPACKTIIRAANRDLHSERECPERKLNCRYCKLSFYFPDIKAHDEICPKFPM-TCEGCGRKKIPREKVRLFVCSFSRNITLSLPCRYAAVGCTE-MVENDKCLEHENKSLAEHLAKVWDYIQHGRKEQNDLSVRMG-----------SLSVQGSPA--------PPFDTLDKKNTTFENIVSVLNREVER--SSHAAEELARQLRAAQEKVE---------------------ALTTKVRQLERTLGQKELIVAELETRMQESELSTYDGVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVS-------SSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVK 473
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 88.5817 bits (218), Expect = 3.711e-18 Identity = 102/382 (26.70%), Postives = 164/382 (42.93%), Query Frame = 1
Query: 451 VKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSL-VKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTK-------------------KLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDL--LKQEEVIRKDQIFIK 1527
V CP C + +++HL +C + C +S GC+ V++ +V EH D+FL + +L N++ E + L Q +L +K I + K +K + N K L + I+ ++ + Q+ +L K+ LDL + + S + +++STL+ D D L F K +L+E T+ N K+ +WKI + + A E IFS ++ S GY++C NG KG F +YF VMKG +D IL WP K VT L++Q ++ + + NS S +K+P +E N + G P F L K I+ D +FIK
Sbjct: 125 VPCP-NACPVTCPRAELDKHLCECPEAELQCTFSNYGCN-VMVKRGKVKEH--EDTFLRDHMLYVLNRNMKLEEQVLGLQQNLDLKEHQIQQLSDTVKWCEKEC-------HQFGQFTGSNGNSLSSTKTLASYID------KSMWLEEQVIQLVSKEH---SRLDLRPILDTLESTK-----QRLSTLEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTS-YNGKL-IWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRADPNSSS--FKRPDSEMNIASGCPRFASHAQLENPKNGCYIKDDTLFIK 477
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf6 (TNF receptor-associated factor 6 [Source:MGI Symbol;Acc:MGI:108072]) HSP 1 Score: 107.071 bits (266), Expect = 3.718e-24 Identity = 95/461 (20.61%), Postives = 188/461 (40.78%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKT------ENIFLIESLEKRGDKS-------------GLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + A PCG R+C CI + + + CP N+ I + + D I LTVKCP + C EL +E+H C+ V CP C +P ++ +VN H++ D V ++ E +E+ Q + I + E + D G + + L+ +++N + ++ L ++ + R + + + + + E + L++ + +++ K+ T + + K+ E+ AQ I++WKI N ++ +E I S ++ GY++C+ + +P + + ++ + M+G YD L WP + + +++Q ++ E + + +++PT RN FG+ F+ L + L+Q I+ D + ++C V
Sbjct: 63 PLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK-CPVDNE------ILLENQLFPDNFAKREILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCPQ----CQRP-FQKCQVNTHIIEDCPRRQVSCVNCAVSMAYEEKEIHDQSCPLANIICEYCGTILIREQMPNHYDLDCPTAPIPCTFSVFGCHEKMQRNHLARHLQENT--QLHMRLLAQAVHNVNLALRPCDAASPSRGCRPEDPNYEETIKQLESRLVRQDHQIRELTAKMETQSMYVGELKRTIRTLEDKVAEMEAQQCNGIYIWKIGNFGMHLKSQEEERPVVIHSPGFYTGRPGYKLCMRLHLQLPTA-QRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEALIRQNHEEVMDAKPELLAFQRPTIPRNPKGFGYVTFMHL-EALRQGTFIKDDTLLVRCEV 507
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 103.605 bits (257), Expect = 5.075e-23 Identity = 102/378 (26.98%), Postives = 172/378 (45.50%), Query Frame = 1
Query: 445 LTVKCPMETCEFMDEL-SMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEEL----SALVKDNAVKDIQ---IKDLNNKINTLIQDRRNDEISGQMKELQEK-QEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNV-------KIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+ V CP + C L S + HL +C C + GC Q ++ H + + H LL E+ N+L ++ L+ + S+ K ++I +SL + +E + KE L S ++ V D Q +K+L+ +I R+N E + MK E Q +V+E E V + +R L+ + D + V +L ++ + V + +WKI + + + A ++S P++ GY+MC V NG KG ++F +M+G YD +L WP K VT L++Q GS+ R + ++ + S +KKPT E N + G P F+ + +L+ I+ D IFIK
Sbjct: 199 VVVSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQ-QIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNE-SVEKNKSI---QSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPF---RQNWEEADSMKSSVESLQNRVTEL--------ESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ--GSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA-QTVLENGTYIKDDTIFIK 556
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 99.7525 bits (247), Expect = 8.688e-22 Identity = 97/358 (27.09%), Postives = 164/358 (45.81%), Query Frame = 1
Query: 517 DCDRKFVGCPYSEIGCS-----KPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEEL----SALVKDNAVKDIQ---IKDLNNKINTLIQDRRNDEISGQMKELQEK-QEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNV-------KIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
DC V CP+ CS + E ++ H + + H LL E+ N+L ++ L+ + S+ K ++I +SL + +E + KE L S ++ V D Q +K+L+ +I R+N E + MK E Q +V+E E V + +R L+ + D + V +L ++ + V + +WKI + + + A ++S P++ GY+MC V NG KG ++F +M+G YD +L WP K VT L++Q GS+ R + ++ + S +KKPT E N + G P F+ + +L+ I+ D IFIK
Sbjct: 195 DCPCVVVSCPHK---CSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNE-SVEKNKSI---QSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPF---RQNWEEADSMKSSVESLQNRVTEL--------ESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ--GSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA-QTVLENGTYIKDDTIFIK 531
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 99.7525 bits (247), Expect = 8.688e-22 Identity = 97/358 (27.09%), Postives = 164/358 (45.81%), Query Frame = 1
Query: 517 DCDRKFVGCPYSEIGCS-----KPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEEL----SALVKDNAVKDIQ---IKDLNNKINTLIQDRRNDEISGQMKELQEK-QEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNV-------KIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
DC V CP+ CS + E ++ H + + H LL E+ N+L ++ L+ + S+ K ++I +SL + +E + KE L S ++ V D Q +K+L+ +I R+N E + MK E Q +V+E E V + +R L+ + D + V +L ++ + V + +WKI + + + A ++S P++ GY+MC V NG KG ++F +M+G YD +L WP K VT L++Q GS+ R + ++ + S +KKPT E N + G P F+ + +L+ I+ D IFIK
Sbjct: 195 DCPCVVVSCPHK---CSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNE-SVEKNKSI---QSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPF---RQNWEEADSMKSSVESLQNRVTEL--------ESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ--GSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA-QTVLENGTYIKDDTIFIK 531
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 96.6709 bits (239), Expect = 8.083e-21 Identity = 82/348 (23.56%), Postives = 146/348 (41.95%), Query Frame = 1
Query: 499 MEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGS----AFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
++H++ C + V C + +GCS+ +VE N +E++ L+ ++L+ L LE + L Q + L++ + + +I N + L N E+ E+V+ + + + + +S KV L+ SI D+ +K+ E+ +F+WKI + ++ + A IFS ++ S GY+MCL V NG +G ++F VMKGP D +L WP VT L++ +N AFR + S +++P ++ N + G P F + + + +R D IFIK
Sbjct: 202 FQDHVRACSKCRVLCRFHTVGCSE----------------------MVETENLQDHELQRLREHLALL------LSSFLEAQASPGTLNQVGPE-----LLQRCQILEQKIATFENIVCVL-----NREV-----------ERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNREHVIDAFRP-------DVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIK 493
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|B6CJY4|TRAF6_CERAT (TNF receptor-associated factor 6 OS=Cercocebus atys OX=9531 GN=TRAF6 PE=2 SV=1) HSP 1 Score: 110.538 bits (275), Expect = 1.746e-24 Identity = 108/467 (23.13%), Postives = 197/467 (42.18%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLND------SFLHNKLLVEYVNNLRNEIEELKTQMSLVKTE---NIFLIESLEKRGDKS-------------GLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSE-NLDLLQNSNEV--VSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + A PCG R+C CI + + + CP N+ I + + D I L VKCP E C EL +E+H C+ V CP C +P ++ +N H+L D S + LV + + EI + ++ V E I + E + D G + + L+ +++N +++ +LI D SG + E++ QE + + L++ +++ ++ + S VS LK +I + K+ EI AQ I++WKI N ++ +E I S ++ + GY++C+ + +P + + ++ + M+G YD L WP + + +++Q ++ E + +++PT RN FG+ F+ L + L+Q I+ D + ++C V
Sbjct: 63 PLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK-CPVDNE------ILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALVDCPQ----CQRP-FQKFHINIHILKDCPRRQVSCDNCAALVAFEDK---EIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSLIPD------SGYVSEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSTYVSELKRTIRTLE-------DKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTA-QRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPDLLAFQRPTIPRNPKGFGYVTFMHL-EALRQRTFIKDDTLLVRCEV 499
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|B6CJY5|TRAF6_MACMU (TNF receptor-associated factor 6 OS=Macaca mulatta OX=9544 GN=TRAF6 PE=2 SV=1) HSP 1 Score: 110.153 bits (274), Expect = 1.933e-24 Identity = 108/467 (23.13%), Postives = 197/467 (42.18%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLND------SFLHNKLLVEYVNNLRNEIEELKTQMSLVKTE---NIFLIESLEKRGDKS-------------GLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSE-NLDLLQNSNEV--VSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + A PCG R+C CI + + + CP N+ I + + D I L VKCP E C EL +E+H C+ V CP C +P ++ +N H+L D S + LV + + EI + ++ V E I + E + D G + + L+ +++N +++ +LI D SG + E++ QE + + L++ +++ ++ + S VS LK +I + K+ EI AQ I++WKI N ++ +E I S ++ + GY++C+ + +P + + ++ + M+G YD L WP + + +++Q ++ E + +++PT RN FG+ F+ L + L+Q I+ D + ++C V
Sbjct: 63 PLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK-CPVDNE------ILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALVDCPQ----CQRP-FQKFHINIHILKDCPRRQVSCDNCAALVAFEDK---EIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSLIPD------SGYVSEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSTYVSELKRTIRTLE-------DKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTA-QRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPDLLAFQRPTIPRNPKGFGYVTFMHL-EALRQRTFIKDDTLLVRCEV 499
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q9Y4K3|TRAF6_HUMAN (TNF receptor-associated factor 6 OS=Homo sapiens OX=9606 GN=TRAF6 PE=1 SV=1) HSP 1 Score: 108.997 bits (271), Expect = 5.623e-24 Identity = 106/466 (22.75%), Postives = 199/466 (42.70%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQ---MSLVKTE---NIFLIESLEKRGDKS-------------GLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTL--IQDRRNDEISGQMKELQEKQEKVSE-NLDLLQNSNEV--VSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + A PCG R+C CI + + + CP N+ I + + D I L VKCP E C EL +E+H C+ + CP C +P ++ +N H+L D ++ E +E+ Q ++ V E I + E + D G + + L+ +++N +++ L +++L I D SG + E++ QE + + L++ +++ ++ + S VS LK +I + K+ EI AQ I++WKI N ++ +E I S ++ + GY++C+ + +P + + ++ + M+G YD L WP + + +++Q ++ E + + +++PT RN FG+ F+ L + L+Q I+ D + ++C V
Sbjct: 63 PLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK-CPVDNE------ILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQ----CQRP-FQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRM--LAQAVHSLSVIPD------SGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLE-------DKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTA-QRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHL-EALRQRTFIKDDTLLVRCEV 499
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P70196|TRAF6_MOUSE (TNF receptor-associated factor 6 OS=Mus musculus OX=10090 GN=Traf6 PE=1 SV=2) HSP 1 Score: 107.071 bits (266), Expect = 2.600e-23 Identity = 95/461 (20.61%), Postives = 188/461 (40.78%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKT------ENIFLIESLEKRGDKS-------------GLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + A PCG R+C CI + + + CP N+ I + + D I LTVKCP + C EL +E+H C+ V CP C +P ++ +VN H++ D V ++ E +E+ Q + I + E + D G + + L+ +++N + ++ L ++ + R + + + + + E + L++ + +++ K+ T + + K+ E+ AQ I++WKI N ++ +E I S ++ GY++C+ + +P + + ++ + M+G YD L WP + + +++Q ++ E + + +++PT RN FG+ F+ L + L+Q I+ D + ++C V
Sbjct: 63 PLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK-CPVDNE------ILLENQLFPDNFAKREILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCPQ----CQRP-FQKCQVNTHIIEDCPRRQVSCVNCAVSMAYEEKEIHDQSCPLANIICEYCGTILIREQMPNHYDLDCPTAPIPCTFSVFGCHEKMQRNHLARHLQENT--QLHMRLLAQAVHNVNLALRPCDAASPSRGCRPEDPNYEETIKQLESRLVRQDHQIRELTAKMETQSMYVGELKRTIRTLEDKVAEMEAQQCNGIYIWKIGNFGMHLKSQEEERPVVIHSPGFYTGRPGYKLCMRLHLQLPTA-QRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEALIRQNHEEVMDAKPELLAFQRPTIPRNPKGFGYVTFMHL-EALRQGTFIKDDTLLVRCEV 507
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q28DL4|TRAF6_XENTR (TNF receptor-associated factor 6 OS=Xenopus tropicalis OX=8364 GN=traf6 PE=2 SV=1) HSP 1 Score: 105.531 bits (262), Expect = 9.119e-23 Identity = 105/494 (21.26%), Postives = 202/494 (40.89%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCD--------------------RKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLL-VEYVNNLRNEIEELKTQMSLVKTENIFL------------IESLEKRGDKSGLEQ----------SKLKEELSALVKDNAVKDIQIKDLNN---------KINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + A PCG R+C CI + + + CP N+ +L++ + D I L VKCP + C EL +E HL CD KF CP +I C +N L D H++ + YV + ++ QM + + + E +++ L++ L+ S++ + + DI D + +++ +ND + + + L+E E++ L + + + V+ LK +I D +L E+ +Q IF+W+I N + +++ +E I S ++ + GY++CL + +P+ + + ++ + M+G YD +L WP + + +++Q G A + + E + + +++PT RN FG+ F+ L+ LKQ + ++ D + ++C+V
Sbjct: 65 PLESKYECPICLMALREAVQTPCGHRFCKACILKSIRDAGHK-CPVDNE----SLME--NQLFPDNFAKREILSLRVKCPSQGCTETMELRHLERHLVRCDFAGVECSQCQSSFPKYSLQKHKFEECPRRQIFC------ENCAVAMALEDKLNHDQTCPLAYVTCEYCQTNLIREQMPAHYSMDCTMAPIPCMYYEFGCTEKMQRNDLARHLQEFTQAHMRMMAQTLRSFSSSVTPTSHMPDISFCDPSQFEPAPPSVATVHSTHTPSQND-CTQETRNLRETIEQLEGRLVRQDHQIRELIAKMETQCTYVNELKHTIRSLD-------NRLGEMESQQCSGIFIWRINNFNSLLKNQEEERPVVIHSQGFYTGKPGYKLCLRLHLQLPSA-QRCANYISLFVHTMQGEYDSLLPWPLQGTIRLSILDQSEGVAMQDQEEVMDTKPELLAFQRPTVARNPKGFGYVTFMHLQ-ALKQRQYVKNDTLLVRCSV 535
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1E101 (TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 151.369 bits (381), Expect = 1.571e-36 Identity = 124/477 (26.00%), Postives = 235/477 (49.27%), Query Frame = 1
Query: 166 ANLEITWKIIKENNFKLIN-PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEI----EELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAV----KDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSV-----RFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQL-NVKI-FVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRS---ESEKYELNSKSGVYKKPTTERN-ASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
+ L+ +++ + N K ++ ++ DL C++C +M +A + CGC YC CI+ +L + + NYCPG C + ++ + D+ + ++ RIS++ VKCP C + EL ++EHL C + V CP IGC + + ++E+ +HL + H +L++ + N L++EI E K +S +K ++ + D+ + L EEL KDN + +DIQ ++ N++ TL+ + ++K+L+ + + ++ ++N EVV + + +++ +K +ID + + LI + NV + F+W+IE SK K T ++SD + + Y+ CL + G G++ +MKG DD L WP + VT +I QD+ ++ + + Y+ N K+ + +P ERN G ++ + + ++ D I + C V
Sbjct: 4 SKLDNVQELLSKYNVKRVDESVNNDLLCILCNKLMRDACESACGCHYCYTCIRIYLSQ-NHNYCPGDKTECKEDYLNLEGDVFRNIRLSTRISRIVVKCPNIRCNYTSELLRLKEHLDKCTPESVECPCVTIGCEEEPLLKDEMAKHLTDQVLRHTQLIMSFCNELKSEINHNNETTKEDISHLKE----VLRVQKALNDEKTAQMEFLIEELRN--KDNMILVLSQDIQ--EVKNEMITLLTSK-----ESELKKLKSDIQIFRQEIEFMKNDLEVVGSTDIKNQVKDLKKEIFGIKMNIDSNNEERERKMNNLIRLNKLCPNVDMDFMWRIEEYSK-----KRRTVTDVYSDSF--QSHNYKFCLNLYIYG-----DNLGLWCVIMKGEKDDFLEWPMRRTVTLSIIEQDSLKTHKTTVFQYDTYQRNKKA--FDRPKDERNDYCIGTDSLVRYSYIKETPMILVNDSIIVACVV 452
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1DBK6 (TRAF-4 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 134.806 bits (338), Expect = 1.161e-30 Identity = 123/472 (26.06%), Postives = 213/472 (45.13%), Query Frame = 1
Query: 187 KIIKENNFKLINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRG-----------DKSGLEQSKLKEELSA------LVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHK----ISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
K+ K+N ++ ++++L C++C+ I+++A CGCRYC +CI +L E + C + C + + DR+ N IS L VKC E C F D L ++ HL C+ + C C + + E N HL N+ L ++L +Y L E ++ + + E++ G + E L+ L + KD + + + + + + R+ + Q K ++E+ + E LL+ + EV+ + K ISR S + + F K++ WKI++ SK+ E A N I S+ ++ S+ GY+MC+ + P G KG ++F +MKG YDDIL WP K V + D+ S + S+ ++ + KS Y++P E N + G P FI +L + ++KD ++I+ NV
Sbjct: 14 KLYKDNKWRFT--INDNLKCVMCQDILLDAIQTDCGCRYCKECIDNYL-ENGEKECVAEYEDCRSVITSY----IYDRATNKEISLLKVKCLYEGCVFEDTLKSIKGHLDFCEYRNEMCSL----CGMEYIIKEESN-HLANECLLR-EVLCQYCRTLLTFKEYNESHLCFESRDLCGKYEAICPYGCTGESKVNLLHHRKSCENKPLECPLHVFDCKQLIPKDQMTEHLNTSSYEHTLTIVTELRK---LEKQNKHMEERMNILIEENQLLKATLEVMKLDLPKNSGSISRDTSLKRANKTIFRNGKYM------------------WKIKSFSKLRENAMRGKNPTILSEAFYTSDFGYKMCMKIYPCGDGVGKGTHLSIFFVIMKGDYDDILPWPFKNKVIITIF--DDFSKSTNLSDTFKPDPKSICYQRPEEEYNIASGSPKFISFSEL---KNFLKKDTLYIQINV 446
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A3M0JFW7 (Uncharacterized protein OS=Hirundo rustica rustica OX=333673 GN=DUI87_30275 PE=4 SV=1) HSP 1 Score: 122.094 bits (305), Expect = 3.078e-26 Identity = 117/446 (26.23%), Postives = 188/446 (42.15%), Query Frame = 1
Query: 244 CLICKGIMINASNAPCGCRYCCQCIKQHLHETDQN--YCPGSNKYC-GINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMME--EHLKDCDRKFVGCPYSEIGCSKPEVRQNE-VNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQ----DRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGS----AFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
C CK I+ A CG RYC C+K+ + Q C Y GI++++ D + + L C C + + E +H+K C R V C + +GC+ EV +NE + EH K L E++ L + + LKT GD L + S L+ NA+ +L+ + L + +R+ + L + E+VS + + + + +S KV L+ SI D+ +K+ + A +F+WKI ++ + A + IFS ++ S+ GY+MCL V NG +G ++F VMKGP D +L WP VT L++Q+N AFR + S +++P TE N + G P F + + + +R D IFIK V
Sbjct: 51 CSDCKNILRRPFQAQCGHRYCSYCLKKIISAGPQKCASCIQEGIYEEGISILETSSAF-PDNAARREVESLPAVCINSGCTWKGTIKEYEFRDHVKTCGRSKVPCRFEAVGCA--EVVENEKLLEH-------ERKCLAEHLYMLLSSVLSLKTHT-----------------GDLKPLPVLSSSQNSSPLLAANAL--CSESELSRSLELLGRCEALERKTVTFENIVCVLNREVERVSLTAEAYSRQHRLDQEKIETLSNKVRQLERSIGLKDLAMAEMEEKIRNMEASTYDGVFIWKITEFARKRQEAITGRSPAIFSPAFYTSKYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHIIDAFRP-------DVTSSSFQRPVTEMNIASGCPLFCPVSVMEAKNSYVRDDAIFIKAIV 460
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: I1ZID8 (TNF receptor associated factor-2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 115.931 bits (289), Expect = 4.283e-26 Identity = 56/162 (34.57%), Postives = 100/162 (61.73%), Query Frame = 1
Query: 205 NFKLINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQ 690
NF++ + ++L C +CK +++NA + CGCR+C +CI +++ + YCPG C + +I D +N +I+++ VKCP ETC+ EL +EEHL+ C K CP+ +GC++P++ ++ HL N +F H+KL+++ ++N+RN+ L T+
Sbjct: 14 NFEVEGGVPDNLKCDLCKNLLVNACQSRCGCRFCSKCIMEYVSRGNL-YCPGGTSECKEENLTICSNIHTDYRVNRKIAKMRVKCPEETCKVYCELVDIEEHLRLCTMKSQNCPFFVLGCNQPKMVIQDLTNHLQNGTFQHSKLIIDIISNMRNDFFGLTTK 174
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A556UFE6 (TNF receptor-associated factor 3 OS=Bagarius yarrelli OX=175774 GN=Baya_10224 PE=4 SV=1) HSP 1 Score: 124.02 bits (310), Expect = 5.109e-26 Identity = 127/513 (24.76%), Postives = 219/513 (42.69%), Query Frame = 1
Query: 214 LINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQN-YCPGSNKYCGINLIDFDRDICIDRSI----------------NIRISQLT----------VKCPM----------------------ETCEFMDELSMMEE-----HLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRND--EISGQMKELQEKQEKVSENLDLLQNSNEVV--------SVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNV-------KIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
+ P + C C+ ++ N CG R+C CI Q L + QN CP + + I F RD+C +R I + + Q+T V CP+ TCEF + + H +DC + V C + GC+ + Q E+ EH N + H +L+V N L ++E++K+++ LE+ GL S+L E + KD K Q++ + + L+ E+ +++EL+ + + E ++ L+ + E + SVR + ++TL+ + D L V +L ++ +L V +WKI + + + A S ++S P++ GY+MC V NG KG ++F VM+G YD +L WP + VT L++Q G A + + ++ + S +++PT E N + G P F+ + +L+ I+ D IFIK V
Sbjct: 463 FVMPPEPKYCCEHCRMVLCNPRQTECGHRFCESCINQLL--SKQNPVCPADMEPLSPDKI-F-RDVCCNREIMTLKVYCRSAKNGCKEQMSLQQVTDHLNMCEYFEVPCPLCKEKIMRKDVPEHLSRKCKYREATCEFCKHKMALTDLQLSIHQQDCPKAQVTCSFLRFGCTYKGLNQ-EMREHESNFASEHLRLMVARNNTLEAKVEDVKSEL-------------LERYKVLPGL-SSRLTE-VEEQYKDMREKYRQVEQKLSSMQKLMSTHSEKLLEVEMELRELRPLR-AMREEVEALRGAVESLRSVVASLDSVRTGSGTHTLTTLETQLSRHDELLSVHDIRLADMDLKLQVLETASFNGTLIWKIHDYKRRKQEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFRQKVTLMLMDQ--GPARKHLGDAFKPDPNSSSFRRPTGEMNIASGCPLFV-AQTVLENGTYIKDDTIFIKVTV 951
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 105.916 bits (263), Expect = 6.226e-24 Identity = 113/470 (24.04%), Postives = 199/470 (42.34%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQ-IKDL--NNKINTLIQ----------DRRNDEISGQM-----KELQEKQEKVSE----------NLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + +A PCG R+C CI++ + +T Q CP N+ + + + D I LTV+C C EL +E H+ C V CP + V ++E+ EH+ N H L+ + N I K S T+ L + G + L+ +L+ +++ ++ + D+ N IN LI D R + +ELQ+ +E V E L L NE S + ++ +K+++L+ES+ E+ AQ ++VW++E S I + + + S P++ GY++CL + PN + + ++ + M+G +D LSWP + + +++Q G + E E +++PT +RN FG+ F++L+ L Q +R D + ++C V
Sbjct: 63 PLESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQK-CPVDNE------VLTEDQLFPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQES-----VWKSELEEHI-NQECSHR--LITCPDCAENIIYAEKQLASHCDTD--CLKAPVACTFSIFGCREKMLRNDLALHMQEFTQMHMRYMADVLRNQTINGLISSHSASAASPTDSRGASSRPEGACQCNQELQQMRETVLELESRLVRQDHKLRELSIRNETQSTQMTELRKKLASLEESMR--------------ELQAQQYQGVYVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNA-PRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQAEG---QHHVEVMETKPDLQAFQRPTVQRNPKGFGYVTFMQLQ-ALHQRGFVRDDVLMVRCEV 496
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 103.605 bits (257), Expect = 3.405e-23 Identity = 116/498 (23.29%), Postives = 208/498 (41.77%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQN---EVNEHLLN-----------DSFLHNKL------LVEYVNN--LRNEIEE------LKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQ-IKDL--NNKINTLIQ----------DRRNDEISGQM-----KELQEKQEKVSE----------NLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + +A PCG R+C CI++ + +T Q CP N+ + + + D I LTV+C C EL +E H+ C V CP + K E+ ++ E + L+ + H +L + EY N +RN++ LK ++ T +IF G + L+ +L+ +++ ++ + D+ N IN LI D R + +ELQ+ +E V E L L NE S + ++ +K+++L+ES+ E+ AQ ++VW++E S I + + + S P++ GY++CL + PN + + ++ + M+G +D LSWP + + +++Q G + E E +++PT +RN FG+ F++L+ L Q +R D + ++C V
Sbjct: 63 PLESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQK-CPVDNE------VLTEDQLFPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQESVWKSELEEHINQECSHRLITCPDCAENIIYAEKQFHEQLCLFANTVCEYCNMELIRNQLASHCDTDCLKAPVAC--TFSIF------------GCREKMLRNDLALHMQEFTQMHMRYMADVLRNQTINGLISSHSASAASPTDSRGASSRPEGACQCNQELQQMRETVLELESRLVRQDHKLRELSIRNETQSTQMTELRKKLASLEESMR--------------ELQAQQYQGVYVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNA-PRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQAEG---QHHVEVMETKPDLQAFQRPTVQRNPKGFGYVTFMQLQ-ALHQRGFVRDDVLMVRCEV 520
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 103.605 bits (257), Expect = 3.405e-23 Identity = 116/498 (23.29%), Postives = 208/498 (41.77%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQN---EVNEHLLN-----------DSFLHNKL------LVEYVNN--LRNEIEE------LKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQ-IKDL--NNKINTLIQ----------DRRNDEISGQM-----KELQEKQEKVSE----------NLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCV---IPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + +A PCG R+C CI++ + +T Q CP N+ + + + D I LTV+C C EL +E H+ C V CP + K E+ ++ E + L+ + H +L + EY N +RN++ LK ++ T +IF G + L+ +L+ +++ ++ + D+ N IN LI D R + +ELQ+ +E V E L L NE S + ++ +K+++L+ES+ E+ AQ ++VW++E S I + + + S P++ GY++CL + PN + + ++ + M+G +D LSWP + + +++Q G + E E +++PT +RN FG+ F++L+ L Q +R D + ++C V
Sbjct: 63 PLESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQK-CPVDNE------VLTEDQLFPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQESVWKSELEEHINQECSHRLITCPDCAENIIYAEKQFHEQLCLFANTVCEYCNMELIRNQLASHCDTDCLKAPVAC--TFSIF------------GCREKMLRNDLALHMQEFTQMHMRYMADVLRNQTINGLISSHSASAASPTDSRGASSRPEGACQCNQELQQMRETVLELESRLVRQDHKLRELSIRNETQSTQMTELRKKLASLEESMR--------------ELQAQQYQGVYVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNA-PRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQAEG---QHHVEVMETKPDLQAFQRPTVQRNPKGFGYVTFMQLQ-ALHQRGFVRDDVLMVRCEV 520
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 100.908 bits (250), Expect = 3.352e-22 Identity = 89/371 (23.99%), Postives = 161/371 (43.40%), Query Frame = 1
Query: 505 EHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIF-LIESLEKRGDKSG----------------LEQSKLKEELSALVKD-NAVKDIQIKDLNNKINTLIQDRRNDEISGQMKE-------LQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGS----AFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+H+K C + C + +GC V + ++++H S+ H LL+ ++ ++ +E L+ Q + + I L +SL + K G L + L A ++Q+ K+ L RR E+ ++ L + E+ + ++ + + + ++ KV L+ ++ D+ K+ E++A +FVWKI + SK + A +FS ++ S+ GY+MCL + NG +G ++F VM+G D +L WP VT L++Q+N AFR + S +++P ++ N + G P F L L + IR D IFIK
Sbjct: 204 DHIKLCTKFRTPCRFHVVGCDM-SVEKEKIHDHERACSYEHLNLLLHFIMGIKVNLESLQPQSLELASHKIQELHQSLRELELKMGQLSAGAPVQGACAPPPPPPPTLATSFTPLPTTVGAALELQLHSEKTKVAEL--SRRCQELELKVGTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIIDAFRP-------DISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIK 564
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252]) HSP 1 Score: 98.5969 bits (244), Expect = 1.618e-21 Identity = 121/519 (23.31%), Postives = 210/519 (40.46%), Query Frame = 1
Query: 244 CLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYC------PGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETC-------EFMDELSMMEEHLKDCD--------RKFV------GCP-------------------------------------------YSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIES-LEKRGDKSGLEQSKLKEELSALVKDNAVKDI--QIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKV-------SENLDLLQNSNEVVSVRFHKISRK---VSTLKESIDDFDMLKFVFTKKLIEITAQLNVK---IFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEV-IRKDQIFIKCNV 1536
C C ++ A CG RYC C+ L C PGS + ++ D D +IN I +L V C + C +F D S E L C+ RK + GCP +SEIGC+ + ++V EH ++ + H LLVE V N++ + + ++ L LE +G L +L D A ++ Q+ L ++ + + I+ +E+++ Q V N++L+Q+ VV+ + ++ RK +S+L++SI +AQ +V F+W+I ++S+ ++ A + +S ++ S G+++C+ + G KG ++F +MKG YD +LSWP K VTF LI+Q+ + + + +S +++P +E N + G P F L L + ++ D +FIKC V
Sbjct: 29 CSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTKCKEDPGSESDSSM-MLTLDH-FFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPCNIGCGLMVLRKTLATHLEKGCPNNKTTCQVCCSALTPAELQSVTYFSLFLKDSKQESPKRKETCVFSEIGCTF-KGNPDKVREHEVSSTSAHLHLLVEVVRNVQMSVPPPPERTVQYPALDLTLNGGELETDSGDTGANDKAL-----SLHDDQAELEVGQQLHALQQRLQIM-----ENIITALNREVEKTQLTVVVLERDNHNNMNLIQHLEAVVAEQQQRLIRKDLQISSLQQSI-----------------SAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQREHV---VDAFRPDLRSASFQRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVV 514
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 112.464 bits (280), Expect = 6.200e-27 Identity = 95/381 (24.93%), Postives = 166/381 (43.57%), Query Frame = 1
Query: 433 RISQLTVKCPMETCEFMDELSMMEE----HLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFL---IESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEI--------TAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
R + + CP CE E S+ E HL C K C +S+ GC Q + EH + H L+ NL ++ L++Q++ L + LEK G SK + L + + AV+ ++ L + + +D + G + ++ + ++ S SV +++ L ++ D F +L E+ TA N K+ VWKI + ++ + A ++S P++ S GY+MC NG +G ++F VM+G YD +L WP + VT L++Q G+A R S+ ++ + S +++PT++ N + G P F+ L+ ++ D IFIK
Sbjct: 97 RCPRYPIPCP-NKCE---EQSIAREELVSHLGICPYKQAECFFSQFGCKYKGTLQG-LKEHESGATQQHLSLVTARSANLELKVSMLQSQLAERANSADLLGTRVRELEKELISVGQTASKNESVLCVVQRMLAVQTERLLRLQESMQGTTRRADHDALRGDLDGTAATLHELGTRVAAIEESGG--SVTHSSTPTRLAALDSALSRHDTQLFAHDTRLAEMDLRFQVLETASYNGKL-VWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQ--GAARRQLSDTFKPDPASSSFRRPTSDMNIASGCPLFVS-HVALESASYLQDDTIFIK 466
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 95.5153 bits (236), Expect = 1.864e-21 Identity = 86/380 (22.63%), Postives = 164/380 (43.16%), Query Frame = 1
Query: 412 IDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELK------TQMSLVKTENIFLIES-LEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
++R +Q + CP E + + +H+ C C + +GC+ + V EH + H L++ + L + L+ T MS + T+ + +E L +G ++L L L + N Q++ L+ +D + M L+E+ + L E R H +++ T+ + + D + +++E TA + K+ VWKI + ++ + A ++S P++ S GY+MC NG +G ++F VM+G YD +L WP + VT L++Q G+A R S+ + + SG +++P + N + G P F+ L+ + D +F++
Sbjct: 48 LERHHKEECAQYPLPCPNNCEEHGIPRAELSQHMSACAMSTKLCGFHMLGCTFKQGTSESVREHEESAVRSHFTLVISRNSELELQCARLQCSIEDHTNMSEMLTQRVAQLEQDLSHWSTLTGSNNTRLGSTLEMLTQHNE----QLQSLHVAQRAPQRDADTAALRRDMATLRERLRALEAALGNPGPCEE----RCHMHEQRL-TMHDGLLDTAERRL----QVLE-TAGYSGKL-VWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQ--GAARRHLSDTFTPDPASGSFRRPDGDMNVASGCPLFVS-HVALEGSSYLVDDTVFVR 409
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 78.9518 bits (193), Expect = 7.741e-16 Identity = 99/513 (19.30%), Postives = 199/513 (38.79%), Query Frame = 1
Query: 223 PLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGI-NLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHL--------------LNDSFLHNKLLVEYVNNLRNEIEEL-KTQMSL---VKTENIFLIESLEKRGDKSGLEQSKLKEELSALVK------DNAVKDIQIK--------------DLNNKINTLIQDRRNDEISGQMKELQEKQEKV----SENLDLL----QNSNEVVSVRFHKI---SRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESN----------NTKIFSDPYFVSENGYQMCLCV-------IPNG-------LVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNA-SFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
PL+ C IC + PCG R+C CI + D + C + N + + + D I LTV+CP + C EL ++EH C+ V C E+ + ++ ++E E + DS H ++ V N ++ +EL + Q+ V + + + G ++ + +S L + + N +K ++I+ N ++ L D + Q +++ ++ LD L + E V ++ H+I S K + + + L ++ E ++L IF W++E S+++ G S + S ++ GY++CL + +P G L + ++ ++++G YD L WP K + +++Q + +E + + + +++P+ RN FG+ F+ + + L +R D + ++C V
Sbjct: 58 PLESKYECPICLMALREPVQTPCGHRFCRACILHSMRLRD------AGPKCPVDNAVLHEGQLFPDNFAKREILSLTVRCPNKPCGHRGELRALQEHQLRCEYAQVPCVRCEMPVCRRDLAKHEEQECMRRIVTCLHCCEKMAYKDSKNHEQMCPLVVVNCKHCQQELIREQLGPHLEVDCQQAQVPCTFSPLGCEAQMVRSLLAAHMHEHTQVHMRLLANGLKILRIQVGQGAQPSSAAGSSAPPNSLSWLSSTSGGDVQTAGASRSQGSRDRAACDCAQELDRLREITRTLEERVVLQLHQIRELSAKTDNQQGLLAEATRLVRSLEARVAESESRLCAGIFTWRVERFSRLLPGGLASGFASDGMHPDAPAVMHSSGFYTGVPGYRLCLRLQVLSGREVPAGAASPSVLLAGRQPHLALFVHLLQGDYDHRLPWPFKGRIRISVVDQCERDSVHV-TEMMDADPQLSAFQRPSVHRNPKGFGYMNFMDI-NTLHHRSYLRDDCLVVRCEV 562
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36]) HSP 1 Score: 108.997 bits (271), Expect = 2.040e-25 Identity = 106/528 (20.08%), Postives = 211/528 (39.96%), Query Frame = 1
Query: 214 LINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQN---------------------------YCPGSNKYC----GINLIDFDRDICIDRSINI-------RISQLTVKCPMETCEFMDE----------LSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLN--DSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDE---------ISGQMKELQEKQEKVS------------ENLDLLQNSNEVVSVRFHKISRKVSTL-----------KESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDN----GSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
+ PLD C +C + + PCG R+C C++ L + YCP C + ++ R C + + ++++ ++ +E CEF + ME+HL+ C++ V CP+ C + ++E+ H N + ++ + + E L+T + ++ L+ + + +K+ +S++ +LS + K+ A + Q+ + + Q+ R + ++ Q +EL E +E++ L +++N + T+ + ++ D + + +++E T+ ++WKI+ ++ + I+S P++V GY+ C V PNG KG ++F +M+G +D +L WP + VTF+L++QD G FR + S +K+PT+ N + G P FI + L+ +R D +FIK V
Sbjct: 11 FVEPLDPKYRCPVCGNALKHPVQTPCGHRFCEGCLEPILRGPSKCPVDGEELKIDGVFKDVCCRREILCLACYCPNRQLGCEWMKDLQYLEEHRANCEYKGVQCHNPGCQEKVAKRDLEAHLERCEFKPSDCQYCLQRIPAASMEDHLQTCEKHPVVCPH----CGAEGICRDELLHHQTNICEQAELPCSFAKHGCHFKGTREALETHFRDQASVHVNLLLTATQNEEKA---RSEMAAKLSQMEKERAKQQEQMYEQREALAVANQNLRTYQGKLNVIERSVAEQRRELAELKERIQLQEVEAAIREQDRRLGMIENEASRGAAPSSGPGSMGGTMALERRQDRNEHQLALHDIQLAEHDLKLQMLEATSYDGT--YIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQDRVHDIGDTFRP-------DPTSSSFKRPTSNMNIASGCPLFISHTN-LQTRAYVRDDTMFIKIAV 521
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO35237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM27]) HSP 1 Score: 100.523 bits (249), Expect = 1.234e-22 Identity = 87/379 (22.96%), Postives = 166/379 (43.80%), Query Frame = 1
Query: 433 RISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSV------------RFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNV-KIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTK-GFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+ ++CP E E + H ++C C +S +GC+ +V++ + EH H LL + + EL+ Q+ EN LE+ E +++KE + NA I K + N+ + + + + E++ + + + N ++S+ +K++R++S L+ SI K I+I ++ F+WKI+ ++ AK N T I+S P++ GY++C + PNG + + ++ +M+G YD IL WP + +T LI+QDNG SE ++ + S +++PT N + G P F + +L+ + ++ +F+K
Sbjct: 155 KCPAFPIECPNECGVKRIERKKLSAHTRECPNALTDCRFSPLGCTY-KVKKIALREHQNKHVIKHMILLGRTTGEPQPNLLELENQLERFDGENTSFKTELERHK----YEFAQMKERFN---DQNARLGIVEKTVANQKGDIAEIWMRFDQENLVGEVRMRDKLKKFKVKTKANKECLLSLMKRLEVQDDSQTNPNKLNRRLSQLESSIT-IHKTKLFQEDLRIQIQQAISYDGTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQDNGMNI---SETFDPDPCSISFQRPTRNINVASGCPRFCS-QTVLRTRGYMNENCVFVK 520
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO32851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV5]) HSP 1 Score: 98.2117 bits (243), Expect = 5.891e-22 Identity = 117/480 (24.38%), Postives = 195/480 (40.62%), Query Frame = 1
Query: 214 LINPLDEDLTCLICKGIMINASN-APCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKC------------------PMETCEFMDEL-----------SMMEEHL-KDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQM--SLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQ-IKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSA----FRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 1536
+ PL + CL C+G++ PCG R C +C + L + + CPG N+ D ID++ + I +L VKC +E C++ D L + +HL KDC K + C Y C + +R+++ HL N L + L EL + + +T+ + E L +GLE +E++ K N + ++ + DL K LI R E + L EK EK +L+ + +S +W+IE+ ++ ++ AK N +FS + S++GY++C V NG K KG V+ +V+KG +D +L WP VTF L++Q++ A R + +P E+NASFG F K ++++ + I++D IF+K +V
Sbjct: 35 FVYPLQKKYICLDCEGLLWYPVQIKPCGHRVCTKCYTKLLSSSAR--CPGCMDELNENIPD------IDKAFHEEIQELDVKCRNVEWNCKWEGCVNEFSSHVEKCDYSDILCENDCGAKFQRRFLTKHLDKDCPEKLITCLY----CDEKHLRKDKKG-HLENCPLLPCPCPNKCDKKLTIHRCELDSHVENDCPRTKLMCEYEVLGCGHRITGLEGGGSREKMPKHNKTNIIAHVKMVADLALKNKELIM--RFSEKLSEHGTLIEKHEKRLNDLEKIAHSQ----------------------------------------------LIWRIEDYTRKMKEAKAGNTDTLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFISVLKGAFDALLKWPFDYRVTFVLLDQNDDPAQRKHIRFSIKPNPCADNEPFLGRPRLEKNASFGGAKFAKHEEIVSR-NYIKEDTIFLKISV 452
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO38873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN4]) HSP 1 Score: 92.0485 bits (227), Expect = 5.973e-20 Identity = 109/465 (23.44%), Postives = 190/465 (40.86%), Query Frame = 1
Query: 244 CLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFD--RDICIDRSINIRISQLTVKC--PMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIG-----CSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNE------IEELKTQMSLVKTE---NIFLIES-LEK-RGDKSGLE-----QSKLK--EELSALVKDNAVKDIQIKD--LNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNV-------KIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNG-LVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
C C+ I+ +A CG RYC CI L P CG + + RD DR I +L V C C + EL + H C+ + C + E G PE QNE S+ ++V + + + K L++ E F E LEK RG ++ LE +S++K E+ + N ++ ++I + N I +++ N E G E+ + + +D L+ ++V+ + + L+ ++ D + + ++ +LN + +WKI N++ A T +S +F +GY+MC + NG + ++F +M+G +D +L WP + VT L++QDN + + + S +++P E N + G P F + L Q IR D +F+K
Sbjct: 24 CAKCRLIVKDAVQTACGHRYCSPCISPLLSRG-----PIQCDVCGSTITKPETFRDKFADRE----ILELHVHCVNQPHGCPWEGELRHRQNHHTKCEFNPISCVHPECGKKLSVAKLPEHLQNECQYREETCSYCEQPVVVARMKEHHEKTCPSYPVNCPKCSKELIRVEVHSTPFTREPRLEKGRGCENTLEVLEDHESRIKKLEQRGGGIGVNGLQSMRISENIDNEAIGDVLRRVANVEAKGADHEVLVVEAHSA--VDELRREVGRLNVKLQESDDIIRRLERQLELHDQGTGLRNLAIADLEERLNTLQGTTFDSVLLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQDN---VEHVIDAFRPDPSSSSFQRPRAEMNIASGCPLFCS-HEQLTQHAYIRDDTMFLK 473
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO48394 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJK8]) HSP 1 Score: 88.5817 bits (218), Expect = 8.975e-19 Identity = 117/480 (24.38%), Postives = 194/480 (40.42%), Query Frame = 1
Query: 211 KLINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQ---SKLKEELS---ALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSE-------NLDLLQNSNEVVSVRFHKISRKVSTLKESI----DDFDMLKFVFTKKLIEITAQLNVKIFVWKIENL------------SKVIEGAKESNNTKI-------FSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSES-EKYELNS---KSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+ I P +++L C IC ++ CG YC CI++ + + CP N+ + I D+ ++ I +S L VKC C + EL ++HLK C K V C P + E + + LH K E + K L F +G +S ++ S ++ L ++DN QI DL+ +++ + Q+ + MKE+ +EK E ++ L + + S H+ ++ TLK+ + + + K Q FVW+I N ++ ++G ++ I S P++ S GY+M L PNG KG + +MKG YD IL WP + +T LINQ +RSE+ E Y ++ K +++P N G+ FI + L + I+ D IFI+
Sbjct: 19 QFIIPPNDELICAICHMVVNEPVLTSCGHSYCKYCIEKWCNGKEVVTCPVDNEQLKPSQIFPDK-----KTDRIVLS-LEVKCTNNPCRWKGELRQKQKHLKICSHKAVKCILEGCNVKVPRILM-EKHTNTCGWRLLHCKPCNLSYPKKDEETVQHKDDCPLAFLPCRFSEIGCTFKGRESARDEHCESAVQTHLHIACETIRDNKE---QISDLHKELDKVRQELQTKSCD-HMKEVNAIREKHDEAIRDNKGQIEALSKEHGIASNTIHENKEQLDTLKKELGIASETIRKNRDQIAKLSTACKTQYTDGTFVWRICNYKDKYKKAVAFATNQEVKGGNSDSDDDISMAGDIMVSLPFYTSRYGYKMRLKAYPNGYGDGKGTHLSLSIRIMKGEYDAILEWPFRRKITLSLINQ--SEQWRSETVEIYPDDATPDKKHKFERPIENENVGCGYSCFISHME-LNSGDYIKDDVIFIE 484
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: ENSORLT00000020861.2 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101167626]) HSP 1 Score: 104.76 bits (260), Expect = 1.629e-23 Identity = 85/367 (23.16%), Postives = 162/367 (44.14%), Query Frame = 1
Query: 505 EHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENI-----------FLIESLEKRGDKS--GLEQSKLKEELSALVKD-NAVKDIQIKDLNNKINTLIQDRRNDEISGQMKE-------LQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGS----AFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
+H+K C + C + +GC V + ++++H S+ H LL+ ++ ++ +E L+ Q V ++ + + L + G G+ + L + L A ++Q++ K+ L RR E+ ++ L + E+ ++ + + + +S KV L+ ++ D+ K+ +++A IF+WKI + +K + A +FS ++ S+ GY+MCL + NG +G ++F VM+G D +L WP VT L++Q+N AFR + S +++P ++ N + G P F L L + IR + IFIK
Sbjct: 205 DHIKFCSKFKAPCRFHVVGCDT-SVEKEKIHDHERQCSYEHLNLLLHFIMGIKVSLESLQPQRLEVASQKLHELHQSLRDLELRMSQLGRSGTAPLQGVCAATLATSFTPLHSAMGAALELQLQSEKTKVAEL--SRRCQELELKVSTFENIVCILNRELERSCATMEAYNRQHRLDQDKIEILSNKVRQLERTVSLRDLSIVEMEGKMKDMSAATYDGIFIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIIDAFRP-------DISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDETIFIK 561
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 104.375 bits (259), Expect = 1.867e-23 Identity = 93/352 (26.42%), Postives = 158/352 (44.89%), Query Frame = 1
Query: 505 EHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNG----SAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNVCLN 1545
+H K C + CP+SE+GC K V +++EH + + H +LL+ V +S+ +T + S E + D SGL + ++ A + DL+ K++ L + L + E+ S L+ + + + + +S K+ L+ S+ D+ + + E+ IFVWKI + S + A +FS ++ S+ GY+MCL + NG +G ++F VM+ YD +L WP VT L++Q+N AFR ++ S S +++P +E N + G P F L L + +R D IFIK V L+
Sbjct: 200 DHAKSCAKSKSACPFSEVGC-KSVVENGKISEHEHSSTMEHLRLLLPMV-------------LSMTRT-RLDTSPSGEWQED-SGLGLYRAPDDGCG-----AAASVPSVDLDKKVSAL---------ENIVCVLNREVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRP-----DITSTS--FQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVDLS 514
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 104.375 bits (259), Expect = 2.067e-23 Identity = 93/352 (26.42%), Postives = 158/352 (44.89%), Query Frame = 1
Query: 505 EHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNG----SAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNVCLN 1545
+H K C + CP+SE+GC K V +++EH + + H +LL+ V +S+ +T + S E + D SGL + ++ A + DL+ K++ L + L + E+ S L+ + + + + +S K+ L+ S+ D+ + + E+ IFVWKI + S + A +FS ++ S+ GY+MCL + NG +G ++F VM+ YD +L WP VT L++Q+N AFR ++ S S +++P +E N + G P F L L + +R D IFIK V L+
Sbjct: 207 DHAKSCAKSKSACPFSEVGC-KSVVENGKISEHEHSSTMEHLRLLLPMV-------------LSMTRT-RLDTSPSGEWQED-SGLGLYRAPDDGCG-----AAASVPSVDLDKKVSAL---------ENIVCVLNREVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRP-----DITSTS--FQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVDLS 521
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: unm_sa808 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101155367]) HSP 1 Score: 91.6633 bits (226), Expect = 3.649e-19 Identity = 67/252 (26.59%), Postives = 115/252 (45.63%), Query Frame = 1
Query: 808 NAVKDIQIKDLNNKINTLIQDRRNDEI---SGQMKE----LQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGS----AFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 1527
A ++Q+ K+ L RR E+ SG + L + E+ + ++ +++ + +S KV L+ ++ D+ +L E+ A +F+W+I + +K + A +FS ++ S+ GY+MCL + NG +G ++F VM+G D +L WP VT L++Q N AFR + S +++P +E N + G P F L L + IR D IFIK
Sbjct: 346 GAALELQLHSEKTKVAEL--GRRCTELEVKSGTFENVVCVLNREVERFTTTMEASNRQHKLDQDKIEALSNKVRQLERTVGLKDLTVAEMEGRLREMAATTFDGVFIWRISDFAKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGLSDALLKWPFNQKVTLMLLDQSNREHIIDAFRP-------DVTSSSFQRPVSEMNIASGCPLFCPLSKLDAKNSYIRDDTIFIK 588
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: ENSORLT00000001369.2 (TNF receptor-associated factor 5 [Source:NCBI gene;Acc:101170323]) HSP 1 Score: 89.3521 bits (220), Expect = 1.855e-18 Identity = 120/542 (22.14%), Postives = 213/542 (39.30%), Query Frame = 1
Query: 199 ENNFKLINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHET--DQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKC---PMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKP---EVRQNEVNEHLLNDSFLHNK-------------LLVEYVNN-----------------LRNEIEELKTQMSLVKTENIFLIESLEKRGDK----------------------SGLEQSKLKEELSALVKDNAVKD--IQIKDLNNKINTLIQDRRNDE--ISGQMKELQEKQEKVSE-NLDLLQNSNEVVS----VRFHKISR--------KVSTLKESIDDFDMLKFVFTKKLIEITAQLNV--------------KIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKG-FFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTE--RNASFGFPYFIKLKDLLKQEEV--IRKDQIFIKCNV 1536
+++ K + L E+ C ICKG+++N CG YC C++ L + CP + I + +D C R IS L V C P+ C + L+ ++EHLK C Y ++ CS P E+ Q + + LN + H + ++ ++V + RN + E V T+ F + +G + + LEQ + + AL++ V+ + + DL ++ +++Q R+ E ++ + L +++ +S LDL Q S + S +R K S TL+E I + + + L AQL + +WKI++ K E + + S P+ GY+M + NG + +G +Y +M G +D +L WP K V+ +++Q A +S + + + + +P E N + GFP FI L L ++ D +F+K V
Sbjct: 53 QHSLKFVMKLKEEFICPICKGVVLNPQQNSCGHIYCFHCLQGLLESSLLSGPVCP--VEKAAITPSEVFQDNCCKR----EISSLEVYCTNSPL--CTSVLALNQLQEHLKSCQ-------YEQLLCSNPGCTELLQRRLLQEHLNATCPHRRESCPHCLQPFQLSVIQDHVQSSCPEVKVGCPDGCSTLVPRNRLTEHGESCPEVHTDCSFKMFGCSVKGKRRKVKLHEEAAVCHHVLLVLKSSAHLEQQVVFVQKEALLRQQEVQTDTLLLSDLQEQLGSVLQQSRSQEHIVATAQRTLSRQEDALSSVQLDLQQVSCGMGSGLDELRRFKTSLDGVMQELLAAETLREHIATLEENRKRHSGLLELHVAQLALNKQHLQELELTSYDGRLIWKIKDFQKRREAEATGQHPCLSSVPFHTGRCGYKMAMKAYLNGDGEGRGTHLSLYVVLMPGDFDALLPWPFKQTVSLSVLDQSG--ARNHQSFNFRPDPTNTCFHQPAAESASNVAVGFPCFISLDALEAPGNAVYVKDDTLFVKVKV 577
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000014700.1 (SMESG000014700.1) HSP 1 Score: 918.687 bits (2373), Expect = 0.000e+0 Identity = 452/464 (97.41%), Postives = 455/464 (98.06%), Query Frame = 1
Query: 163 MANLEITWKIIKENNFKLINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNVCLNKEP 1554
MAN EI WKIIKENNFKLIN L +DLTCLICKGIMINASNAPCGCRYCCQCIKQHL+ETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEF DELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENI LIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKF F K+LIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNVCLN EP
Sbjct: 1 MANFEIVWKIIKENNFKLINSLKKDLTCLICKGIMINASNAPCGCRYCCQCIKQHLNETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFTDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENICLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFAFAKRLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNVCLNNEP 464
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000014700.1 (SMESG000014700.1) HSP 1 Score: 861.677 bits (2225), Expect = 0.000e+0 Identity = 423/430 (98.37%), Postives = 425/430 (98.84%), Query Frame = 1
Query: 265 MINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNVCLNKEP 1554
MINASNAPCGCRYCCQCIKQHL+ETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEF DELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENI LIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKF F K+LIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNVCLN EP
Sbjct: 1 MINASNAPCGCRYCCQCIKQHLNETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFTDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENICLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFAFAKRLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNVCLNNEP 430
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000014698.1 (SMESG000014698.1) HSP 1 Score: 654.055 bits (1686), Expect = 0.000e+0 Identity = 334/527 (63.38%), Postives = 393/527 (74.57%), Query Frame = 1
Query: 40 MPFCMILTTNTVENFLLAVRQFSIVELTNQRIALNFLTKYFMANLEITWKIIKENNFKLINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLN----------VKI--------------FVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNVCLNK 1548
MPFCMILTTNTVENFLLAVRQFSIVELTNQRIALNFLTKYFMANLEITWKIIKENNFKLIN LDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHL+ TDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGC KPEVRQNEVNEHLL DSF HNKLLVEYVNNLRNEIEEL TQM KTEN+ LIESLEK LEQSK +E+ A+ + L+ +I L Q+R + + ++ L+ +QEK+ E+++ L +N ++ +++ ++ LK+ +DD D T+K+ E+ +N V+I F+WK+E+ SKV+E + S IFSD +F+SENGY+M L PNGL K+KGFFG+YFN+++GPYDDIL WPC+IDVT E++NQ + S + YE Y+KP +ERN GFPYF+KL LLKQ ++I+ DQ+FIKC VCL K
Sbjct: 1 MPFCMILTTNTVENFLLAVRQFSIVELTNQRIALNFLTKYFMANLEITWKIIKENNFKLINHLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLNGTDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCCKPEVRQNEVNEHLLKDSFPHNKLLVEYVNNLRNEIEELNTQMIKTKTENVCLIESLEKIKKNFKLEQSKFMKEIKAM-------KVHASSLDAEIVRLKQERTHGQDLEKLNLLEGRQEKIEESVENLHEANSTLNGTVGQLTNSLNLLKDEVDDLDNEMDNLTEKISELKENVNGINKTNESNEVQIDKTQLKLDNRVNKEFIWKLEDFSKVLENCENSATKMIFSDSFFISENGYKMSLYACPNGLGKSKGFFGLYFNIVRGPYDDILFWPCQIDVTLEIVNQVTKWSQLSGTRLYENLPNDFAYRKPRSERNDGNGFPYFVKLDYLLKQSQIIKNDQLFIKCFVCLYK 520
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000014700.1 (SMESG000014700.1) HSP 1 Score: 630.172 bits (1624), Expect = 0.000e+0 Identity = 312/323 (96.59%), Postives = 315/323 (97.52%), Query Frame = 1
Query: 163 MANLEITWKIIKENNFKLINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFVFTKKLIEITAQLNVKIFVWKIENLSK 1131
MAN EI WKIIKENNFKLIN L +DLTCLICKGIMINASNAPCGCRYCCQCIKQHL+ETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEF DELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENI LIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKF F K+LIEITAQLNVKIFVWKIENLSK
Sbjct: 1 MANFEIVWKIIKENNFKLINSLKKDLTCLICKGIMINASNAPCGCRYCCQCIKQHLNETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFTDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENICLIESLEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFAFAKRLIEITAQLNVKIFVWKIENLSK 323
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000014706.1 (SMESG000014706.1) HSP 1 Score: 588.571 bits (1516), Expect = 0.000e+0 Identity = 301/510 (59.02%), Postives = 368/510 (72.16%), Query Frame = 1
Query: 163 MANLEITWKIIKENNFKLINPLDEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLHETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFMDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIFLIESLE-----------------------------------------KRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESID----DFDMLKFVFTKKLIEITAQLN---VKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNVCLNK 1548
MANLEITWKIIKENNFKLINPL+EDLTCLICKGIMINASNAPCGCRYCCQCIKQHL+ TDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQL VKCPMETCEF DELSMMEEHLKDCDRKFVGCPYSEIGC KPEVRQNEVN+HLLNDSF HNKLLVEYVNNLRNEIEELKTQMS TEN LIE+L K+ +K EQ +LKEE+S LV++N I I L +I TL ++ + +++ +K L+ KQE++ +D + +N+V+S + ++ V+ L+ +ID D K F +L ++ + + K+F+WKIEN SKVI AK++ N +I+SD +FV ENGYQMCL V P GL K+ GF GVYFN+M+GPYD+IL+WPC+IDVT ELI+QD+G AF+S ++ Y+ NS + VY+KP + N+ G+P+FIKL LLK ++ R +Q+FIKC VCLN+
Sbjct: 1 MANLEITWKIIKENNFKLINPLNEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLNGTDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLVVKCPMETCEFTDELSMMEEHLKDCDRKFVGCPYSEIGCCKPEVRQNEVNKHLLNDSFPHNKLLVEYVNNLRNEIEELKTQMSKTNTENFCLIENLGESRKRFIYQQAVHKKEIDILAEENNAMKIQINSLNFKIGAFKQNEKQ--EQVQLKEEMSRLVEENKAIGIHINSLKAEIATLKKENKQEKLEKTLKGLEGKQEEIEGKVDFAERANKVISDKVEQLKETVNNLQGNIDSVKLDIFTEKLSFENRLSDLEERFDNQENKVFIWKIENFSKVIADAKQNRNKRIYSDSFFVFENGYQMCLYVCPIGLGKSSGFVGVYFNIMQGPYDNILAWPCQIDVTLELIDQDDGLAFKSSTKLYDFNSDNEVYEKPISGMNSGSGYPFFIKLDYLLKMNQLFRNNQLFIKCIVCLNE 508 The following BLAST results are available for this feature:
BLAST of TNF receptor-associated factor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TNF receptor-associated factor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of TNF receptor-associated factor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30004739 ID=SMED30004739|Name=TNF receptor-associated factor|organism=Schmidtea mediterranea sexual|type=transcript|length=1565bpback to top protein sequence of SMED30004739-orf-1 >SMED30004739-orf-1 ID=SMED30004739-orf-1|Name=SMED30004739-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=506bp MPFCMILTTNTVENFLLAVRQFSIVELTNQRIALNFLTKYFMANLEITWKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
