Cytochrome P450 2K1-like protein

Query:  301 IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQ-SLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILR---RTNRKVL--FDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1560
            + + + R  +K+G VF V  G R V++L   + ++ A VD    +SGR K++       GY  I F +G  W++ R F +    DFG+GK    E  ++E   LI+EL    G  +D + L    T NII   +  KRF  ++ ++  + NL  Q       +         F ++  L    L+     +R+V      ++  +   +++HR+TLD  S  +DLID +L+  H  K  + +  +F+   L   +L L  AG ETT+T+L + FL M KY  + ++V+ EI  +IG  R P  +DR  + YT+AV+ EI R S + P+ + H     +S  GY +PKD  VF  L     D   +EKP  F P+ FL  D NG +K T  E    F +GKR C GE +A+ E F+FFT+I+Q F +
Sbjct:   51 LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVI-FANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSV---------FGQLFELFSGFLKYFPGAHRQVYKNLQEINAYIGHSVEKHRETLD-PSAPKDLIDTYLL--HMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFL--DANGALKKT--EAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSM 459          

Query:  319 RLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLP---LFDKMTWLCDWILRRTNRKVL-FDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVR 1563
            +L K++GS++ V  G R V++L+ YQ VK A VD G  +SGR         +    IAF  G+ W++ R F +++  +FG+GK    E   +E  +L+ EL    G+  D + ++     NII   +   RF   +++  TI  L        D  Q++  + P   L+D    L DW+     R    F  +  L+   + +H+ +LD  S   D I  FL K  + K    S   F    L   +  LL  G +T +T+L  +FL + KY  +Q +V EEI  ++G+ R P   DR  + YT AV+ E+ R + + P+ L HR   D++  G+ +PK   V + L   H+D   +  P+EF PE FL  D N   K +       F  G+R C GESLA+ME F++ T+I+Q F ++
Sbjct:   57 KLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLLTIIRL------INDNFQIM--SSPWGELYDIFPSLLDWVPGPHQRIFQNFKCLRDLIAHSVHDHQASLDPRSP-RDFIQCFLTKMAEEKEDPLS--HFHMDTLLMTTHNLLFGGTKTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGRARLPALKDRAAMPYTDAVIHEVQRFADIIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFL--DANQSFKKSP--AFMPFSAGRRLCLGESLARMELFLYLTAILQSFSLQ 460          

Query:  166 LC-TFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGN--------LGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAV--DKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSD 1584
            LC +F+L  +++ +  RR  +P G    PT   LP +G + QI+   I + +    K +G VF V +GM  +++ + Y+ VK A +D+G  +SGR     S  ++    I   +G+ W+  R F L    +FG+GK    +  ++E   L++EL        D + ++     N+I   +  KRF  K+  + T+          L    ++  +   LL    P               T+ KVL +       ++E++ EH+ +LD+N+   D ID FLIK  Q K +  S  +F    L     +L +AG ETT+T+L +  L + K+  +  KV EEI ++IG+ R P   DR  + YT AV+ EI R S + P  + H    D+    Y +PK   + + L +   D+K +  P  F P  FL  D NG+ K   ++    F  GKR CAGE LA+ME F+F T+I+Q F ++  +D+ +
Sbjct:    9 LCLSFMLLFSLWRQSCRRRKLPPG----PTP--LPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFP--------------GTHNKVLKNVALTRSYIREKVKEHQASLDVNNP-RDFIDCFLIKMEQEKDNQKS--EFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL--DKNGNFK--KSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKN 466          

Query:  247 PTEKGLPFVGVLHQIETPIFRYYERLIK---KHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRW-KVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGN--LGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVR 1629
            P    LPF+G   Q+ T   + Y  L+K   ++G VF +  G R V++L  +  VK A VD    +SGR  + +   L  GY  +AF +GE  +  R F +     FG+GK    E  ++E  +LID L   +G  +D +  +     N+IS  +   RF  ++ ++ ++    LG          QL      +F  +        ++  +++    ++  + ++++ +++TLD NS   D ID FLI+  + + +  +  +F    L   +L L  AG ET +T+L + FL + K+  ++ KVHEEI  +IGK R P   DR  + YT+AV+ EI R   + P+ L HR   D+    +++PK   VF  L +   D + +  P++F P+ FL  D  G  K   ++    F +GKR C GE LA+ME F+FFT+IMQ F  +  +   D       +G   I R
Sbjct:   35 PGPTPLPFIGNYLQLNTE--QMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYG-VAFSNGERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLY----EMFSSVMKHLPGPQQQAFKEL--QGLEDFIAKKVEHNQRTLDPNSP-RDFIDSFLIRMQEEEKNPNT--EFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFL--DKKGQFK--KSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKDIDVSPKHVGFATIPR 485          

Query:  247 PTEKGLPFVGVLHQIETPIFRYYERLIK---KHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRW-KVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKV-----LFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVR 1629
            P    LPF+G   Q+ T   + Y  L+K   ++G VF +  G R V++L  +  V+ A VD    +SGR  + +   +  GY  + F +GE  +  R F +    DFG+GK    E  ++E  +LID L    G  +D +  +     N+IS  +   RF  K+ ++ ++  +          L +  +T     ++  +   +++           L   ++  + ++++ +++TLD NS   D ID FLI+  + + +  +  +F    L   +L L + G ET +T+L + FL + K+  ++ KVHEEI  +IGK R P   DR  + Y +AV+ EI R   V P++L  R   D+    +++PK   V+  L +   D   +  P++F P+ FL    N   ++  ++    F +GKR C GE LA+ME F+FFT++MQ F ++ S+   D       +G   I R
Sbjct:   35 PGPTPLPFIGNYLQLNTE--QMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYG-VVFSNGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRM---------MLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLDPNSP-RDFIDSFLIRMQEEEKNPNT--EFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFL----NEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPR 485          

Query:  193 IFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPI--FRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVS-QSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSR-KEDKYKTI--------GNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLN-SEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1560
            ++WK   R   P G    PT   LP +G L  +  P   ++ + R   K+G ++    G R  I+++ Y+ +K  F+ DG  Y+ +  ++ Q     G   +   +G  W+  R F +  F DFG+GK    +    E   + +  +   G+ VD++D+      N+I++ +   RF   + D+++TI        G     +++ +  L  + Y +P           IL R   K       +    +I+ H+K +D    E  D ++ FL +Q + +AS G  + F+  QL  + L+L  A L TT+ ++ W F +   Y   QQK+HEE+  +IG ER   T D+ +L YT A ++EI R +++ PL L+H    D+ + GY +PK   V + +    +DE V+ +P  F PERFL  D  G +K    E L  F +GKR+C GE LA+ME F+F  +   R+ V
Sbjct:   18 LYWK---RRNWPAG----PTP--LPLIGNLLSLRNPAPGYKAFARWTAKYGDIYTFWLGTRPYILVSSYEALKETFIKDGETYADKKPMAFQESFRGGSYGVVETNGPFWREHRRFAIHQFRDFGLGKDRMEQRIMLEVEDIFNNCDKTIGEGVDLTDIFDRAVGNVINQMLFGYRFDETRADEFRTIRAFFNFNSGEFASFSMRVQFFLPWMGYIMP--------GPTILDRF--KKYQKGFTEFFGTQIENHKKEIDFELEENSDYVEAFLKEQRKREAS-GDFESFSTKQLSNMCLDLWFAALMTTSNTMTWCFAYTLNYLDAQQKLHEELDRVIGSERHINTADKPNLPYTNAYINEIQRTANLVPLNLLHMTTRDTVLKGYNIPKGTGVVAQISTVMYDENVFPEPYIFKPERFLDDD--GKLKKV--EQLVPFSVGKRQCLGEGLARMELFLFIANFFNRYRV 462          

Query:  166 LCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPI--FRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFID--GEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRF-SRKEDKYKTIGNLGQQALKQKDCLQL-LFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLD---LNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSED 1575
            L TFL    ++  + +R   P G         LP  G L  I  P   ++ +ER  KK+G V+    G    I++N +  +K  F+ D   Y+ +  +    L  G      ID  G MW+  R F L    DFG+GK++  E    E   +   L+   G   DV ++      N++++ +   RF   KE++Y+ + ++     +    L + L   +P+F K   L    L     K   D       ++I+ HR  +D   LNSE  D ++ FL K+ + + S G S+ +++ QL  + ++L  AGL TTT ++ W+  ++  +  +Q K+HEE+  +IG +R  TT D+ DL Y  A ++E  R  ++ PL L H    D+ I+G+ +PK   V + +     +E+V+  P  F P+RF+  D NG +K    + L  F +GKR C GE LA+ME F+F  + + R+++  S++
Sbjct:    6 LLTFLTIYFVYELYWKRRNFPPG------PCPLPVFGNLLSIANPPPGYKAFERWTKKYGDVYTFWIGNTPHIMINTWDKIKETFIRDADTYTNKVVLPMVTLSRG-GEYGIIDSNGAMWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDVPEVFDHAVANVVNQLLFGYRFMGPKENEYQELKHIIDSPAEIFGKLHIFLAMNIPIFAK---LLPESLYEGPIKTFRDTTLAFFNKQIEAHRHRIDFEDLNSESTDFVETFL-KEQKRRESEGDSETYSNIQLLNVCIDLWFAGLNTTTNTITWAISYVLHHPEVQDKIHEELDKVIGSDRLITTADKNDLPYFNASINESQRGINILPLNLQHATTRDTVIDGFKIPKGTGVVAQISTVMNNEEVFPDPYTFNPDRFI--DENGKLKKV--DELAPFSVGKRSCPGEGLARMELFLFIANFLNRYKIHPSKE 469          

Query:  196 FWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFI--DGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKW-VDVSDLIHLYTVNIISKFITNKRFSRKE-DKYKTIGNLGQQALKQ-KDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFE 1557
            +WK ++    PKG   +P    LPF+G +HQ     + +Y++ L K +G  F +       I+L DY+ +K AFV+ G  ++ R   S   L+  +     +  DG+ W++QR   LK+  DFG+G+++  E   +    ++ +LE +N K  VDV   I L   N+I++ +    +  ++ +K+KT   +  + L+  +  + LL    P    +  + D  +   N K    +    ++EE+    K  D  SE E+ +  ++    Q+K +       T+       L+  LAG+ETT+ SL W   FM KY  +Q KV +EI++ +G  R P+ +D+ ++ YTQAV+ E+ R S++ P    H+   ++ I+G  VP  +LVF+ L++   ++ V+E P+ F P R+L +D     K    + +  F +GKR C GE LA+ME F+ F++++Q++E
Sbjct:   20 YWKVSKY---PKG--PLP----LPFIGNIHQFPPDNVQKYFDVLSKTYGPCFTIWIPF-PAIVLTDYEHIKDAFVNQGDTFTYRAHRSPETLLPVHDHTGILASDGDHWRLQRRTSLKILRDFGLGRNLMEEQVIRSVHEMLIQLENINDKKNVDVFWPIQLCVGNVINETLFGFHYKYEDSEKFKTFVKIVDKHLRHLQGKMPLLVSAFPWLKHVPIVGD--IGYHNIKNNISSYHTFIEEEVATQVKKYDGESEPENFVHAYM---QQMKQTGNPGLDITNL--CATVLDFWLAGMETTSNSLRWHLAFMMKYPEVQDKVRKEILDNVGTARLPSMSDKPNMPYTQAVIHEVQRCSNMIPFLGSHQCKEETEIHGNRVPAGSLVFAQLWSVMRNDTVFEDPETFNPSRYLQSDGKTFDKAVLEKTI-PFSIGKRNCVGEGLARMELFLIFSALIQKYE 461          

Query:  247 PTEKGLPFVGVLHQIETPIFRY--YERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQ-SLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRF-SRKEDKYKTIGNL--GQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLN---SEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDAL 1590
            P    LP  G L  I  P   Y  +ER  KK+G ++    G    I++N +  +K  ++ D   Y+ + ++    L   G   I   +G  W+  R F L    DFG+GK++  E    E   +   L+   G   D+ ++      N++++ +   RF   KE +Y+ +  +      L  K  +  L   +P+  K   L    +     K   D       ++I+ HR+ +DLN   SE  D ++ FL K+ + + S G S+ F++ QL  + ++L  AGL TTT ++ W+  ++  +  +Q KVHEE+  +IG +R  TT D+ DL Y  A ++E  R  ++ PL L H    D+ ING+ +PK   V + +     +E+V+  P  F P+RF+  D +G +K    E L  F +GKR C GE LA+ME F+F  + + R+++  S++   ++
Sbjct:   27 PGPCPLPVFGNLLSIANPPPGYEAFERWTKKYGDIYTFWIGNTPHIMINTWDKIKETYIRDAETYTNKVRLPALDLFRGGEYGIIDSNGATWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDIPEVFDHAVANVVNQLLFGYRFVGPKESEYQELKRIIEAPTDLFGKPHM-FLAMNIPVIAK---LMPEFMYEGPFKDFRDTAFAFFNKQIEAHRQEVDLNDLNSESTDFVETFL-KEQKRRESEGDSETFSNVQLSNVCMDLWFAGLNTTTNTITWAISYILHHPEVQDKVHEEMDKVIGSDRLITTADKNDLPYFNAFINEAQRGINIVPLNLQHATTRDTVINGFKIPKGTGVVAQISTVMNNEEVFPDPHTFNPDRFI--DEHGKLKRV--EELAPFSVGKRSCPGEGLARMELFLFIANFLNRYKIYPSKEGPPSM 474          

Query:  247 PTEKGLPFVGVLHQIET--PIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRW--KVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSR-KEDKYKTIGNL--GQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDL-NSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1560
            P  + LPF+G L  ++T  P +  +    K++G +F      +  +I+  Y+ +K  FV DG  Y  +      +  L   Y  +   +G MW+  R F L    D G+GK +  E    E   L  EL+   G+ +D+  LI     N+I+  + NKRF   K D++  + +L  G + +  +    L+ Y +P     T L    L    R    + +D     +IDEHR  +D  N+E  D ++ +L K+ + +   G  K F + QL  +  +L +AGL TTT ++ W   +      +Q+K+ EE+  +IG +R  +T D+ DL Y QA + E  R +++ PL L+H    D+ I+G+ + K   V + +    +DEKV+ +P +F PERF+    NG  K+   + +  F +GKR+C GE LA++E F+FF +I  R++V
Sbjct:   27 PGPRPLPFLGNLLSLKTLKPGYEAFSNWKKEYGPIFTFWMANKPFVIIASYEKMKETFVKDGDTYVDKQLTHTEKERLGENYG-VLDTNGHMWKEHRRFTLTQLRDLGLGKDLMQEKILMEVEELFKELDAHGGEEIDLPKLIDRSVGNVINLTLFNKRFDMDKRDEFAHLKSLIDGMRNVTSQ-FRYLIQYLVPW--TSTVLPGPTLSEKVRAKR-EELDDFFYSQIDEHRNEIDFDNTENLDFVEAYL-KEQKKREEDGDFKTFCNKQLCAMLFDLWIAGLMTTTMTMTWGLSYYLYNPEVQRKIREELDKVIGNDRLISTADKNDLPYLQAFVTETQRTANIIPLNLIHMTTRDTVIDGFPIQKGTGVIAQISTVMYDEKVFPEPYKFKPERFIE---NG--KFKKVDEVIPFSIGKRQCLGEGLARIELFLFFANIFNRYDV 461          

Query:  235 LRRIPTEK-GLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGI-----GKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFY--TLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFT----DFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSE 1572
            LR++P    GLP +G L  + +     +  L K++GS+F+ R G +  ++++DY+ ++  F  +   ++GR        ++GY  I    G++W+ QR F+      FG+     GK    +    E    I  L   +G+ VD+S +I +   N+I   + + RFS  + K++    L ++ ++    +  + Y  T+  F  ++   + I +  NR      + +  Q+ ID+H+++ D N+   DL+D +L +  + KA    ++ F     + QL ++ ++L  AG+ET  T+L W  +FM +     ++V +E+  ++G+ R PT  D + L  T++ + E  R SS+ PLA  H    D  +NGY +P  + V   + + H D  +WEKP+EF P RF+ T+  G ++    E    FG+G+R C G+ LA+ME F+FF S M  F++   E
Sbjct:   50 LRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTLNGYG-IINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQ--NRA----EMQRFYQDVIDDHKRSFDPNNI-RDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTE--GKVR--KPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPE 493          

Query:  235 LRRIPTEK-GLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGI-----GKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFY--TLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFT----DFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSE 1572
            LR++P    GLP +G L  + +     +  L K++GS+F+ R G +  ++++DY+ ++  F  +   ++GR        ++GY  I    G++W+ QR F+      FG+     GK    +    E    I  L   +G+ VD+S +I +   N+I   + + RFS  + K++    L ++ ++    +  + Y  T+  F  ++   + I +  NR      + +  Q+ ID+H+++ D N+   DL+D +L +  + KA    ++ F     + QL ++ ++L  AG+ET  T+L W  +FM +     ++V +E+  ++G+ R PT  D + L  T++ + E  R SS+ PLA  H    D  +NGY +P  + V   + + H D  +WEKP+EF P RF+ T+  G ++    E    FG+G+R C G+ LA+ME F+FF S M  F++   E
Sbjct:   50 LRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTLNGYG-IINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQ--NRA----EMQRFYQDVIDDHKRSFDPNNI-RDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTE--GKVR--KPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPE 493          

Query:  487 IAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELE----TLNGKW--VDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPT-TNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1560
            +   DGEMW  QR F+L+   +FG  +S   +I   E   L+ +L+       GK   +++ DL  +Y +N +   ++ +R+     +   +     +  K  D +  LF   PL   + ++               ++   + +EI+ HR T     E  DL+D +L  Q +     G    F+D  L  + L++ LAG ETT  SL + F+ +     IQ++  +EI  ++G ER P  + DR  L Y +A+  E  R+  +    + HRA+ D+ ++GY +PKD +V +       +   +  P+ F P+R+L    +G +K    E  N FG G+ RC G+ L +   F+F T+++Q F++
Sbjct:  118 VLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPL---LRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKG---MFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL---FDGHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          

Query:  487 IAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELE----TLNGKW--VDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPT-TNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1560
            +   DGEMW  QR F+L+   +FG  +S   +I   E   L+ +L+       GK   +++ DL  +Y +N +   ++ +R+     +   +     +  K  D +  LF   PL   + ++               ++   + +EI+ HR T     E  DL+D +L  Q +     G    F+D  L  + L++ LAG ETT  SL + F+ +     IQ++  +EI  ++G ER P  + DR  L Y +A+  E  R+  +    + HRA+ D+ ++GY +PKD +V +       +   +  P+ F P+R+L    +G +K    E  N FG G+ RC G+ L +   F+F T+++Q F++
Sbjct:  118 VLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPL---LRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKG---MFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL---FDGHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          

Query:  163 YLCTFLLGAAIFWKFTR-RTP--IPKGLRRIP-------TEKGLPFVGVLHQIETPIFRYYERLIKKHGS-VFAVRYGMRDVIILNDYQTVKSA-----FVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKED-KYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKL---VQEEIDEHRKTL--DLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEI---VNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDAL 1590
            +LC  L+G  I+   +  R P   P G R +P         K    VG  H +       +ER  K   S +  ++ G   V++   ++ VK       F     N+  R +      M     I   DG++W   R F +K   + G G+S        E   L+ +LE    + ++    +    +N++   I  KR +R+ED   + + +L  +  K  D    L    P      WL      RT   ++     +L     + I+EHR+ L  D +    DLI  +L ++ + +++ G S  F + QL    L+  +AG +TT+ ++  + + ++    +Q+K+  ++   V     + FP  + R+  +Y  A + E+ R   + P+    RA+  + + GY +PK+A +  +L + H D++ W+ P EF PERF    I+   K   +E    FGMG+RRC G++LA+   F F   I+Q F V      S ++
Sbjct:    6 FLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHIL-------FERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRT-----MGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFP------WLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYL-QEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERF----IDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSM 483          

Query:  163 YLCTFLL-GAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTI-GNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRK-----VLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDAL 1590
            +LC FLL G  I  K  +  P        P    LP +G LH I+ + I   + +  +++G++F+ R     +++LN Y  VK  ++  G N + R  +     + G   +    G  W+ QR F L    +FG+GK         EC +L + +    G+  D   L++    N+I   +   RF   +  ++T+  N+ +    +      L+   P          W++ R          L+  V   V+E+++EHR   D  S   D ID FL +  +LK  T +   F    L   SL+L +AG ETT+T+L W  L+M KY  IQ KV EEI  ++G  R P+ +DR ++ YT AV+ EI R+ ++AP+ L      D+ I  Y +PK  +V SNL +  FDE  WE P  F P  FL  D  G  K+   +    F +GKR C GE LA+ME F+FF+S++QRF       V  +L
Sbjct:   18 FLCVFLLLGDYIKNKAPKNFP--------PGPWSLPIIGDLHHIDNSKIHLQFTKFAERYGNIFSFRLFGPRIVVLNGYNLVKEVYIKQGDNLADRPVLPLFYEIVGDKGLILSSGYKWKHQRRFALSTLRNFGLGKKSLEPSINVECGFLNEAISNEQGRPFDPRLLLNNAVSNVICVLVFGNRFDYSDHHFQTLLKNISEAVYLEGSICNQLYNMFP----------WLMERLPGPHKTIITLWRKVTDFVREKVNEHRVDYD-PSNPRDYIDCFLTEMEKLKDDTAAG--FDVENLCICSLDLFVAGTETTSTTLYWGLLYMIKYPEIQAKVQEEIDAVVGGSRQPSVSDRDNMPYTNAVIHEIQRMGNIAPINLARSTSEDTQIGNYSIPKGTMVTSNLTSVLFDESEWETPHSFNPGHFL--DAEG--KFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEPSL 476          

Query:  247 PTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHR------KTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVS-DALYEEALIG 1611
            P  K LP VG L  ++ T  F  + +L K +G+VF V  G    ++L  Y+TVK A V+    +  R       +M+    I F +GE W+  R F L    DFG+GK  S E   +E  +L  E +   GK  D +  ++    NIIS  +   RF   + ++  + +   + ++    + +  Y     D   WL  ++    N++++   V+ ++Q  +   +      +TL+ N +    +D FLI++   + S      F +  L      L +AG +TT T+L W  + M+KY  IQ +V EEI  +IG  R P   DRK L YT AV+ EI R++++ PL+L HR  +D + NGY++ K   V   L +   DE  WEKP  FYPE FL  D  G  ++   +    F  G+R C GESLA+ME F+FFTS++Q +       VS D L  + ++G
Sbjct:   46 PGPKPLPLVGNLLTLDLTRPFDTFFKLSKTYGNVFQVYLGPEKAVVLVGYKTVKEALVNYAEEFGDREIGPGFSIMNDEHGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMWLY-----DIFPWLGPFL---KNKRII---VENIIQSRVQMTKLITALLETLNPN-DPRGFVDSFLIRKLSDEKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGG-RQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFL--DEKG--QFVRRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVG 491          

Query:  163 YLCTFLL-GAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQA--LKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKV--LFDAVDKLVQEEIDEHRKTLD-LNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDAL 1590
            +LC FLL G  I  K  +  P        P    LP +G LH I+ + I   + +  +++G++F++R     +++LN Y  VK  ++  G N + R  +     + G   I    G  W+ QR F L    +FG+GK         EC +L + +    G+  D   L++    N+I   +   RF   +  ++T+     +A  L+   C QL       ++   WL    L  +++KV  L+  V   ++++++EH+   D LN    D ID FL +  +LK  T +   F    L   +L+L +AG ETT+T+L W  L+M KY +IQ KV EEI  ++G  R P+ +DR ++ YT AV+ EI R+ ++ P+ +      D  I  Y VPK  +V SNL +  FDE  WE P  F P  FL    N + K+   +    F +GKR C GE LA+ME F+FF+S++QRF       V  +L
Sbjct:   18 FLCVFLLLGDYIKNKAPKNFP--------PGPWSLPIIGDLHHIDNSKIHLQFTKFAERYGNIFSLRLFGPRIVVLNGYNLVKEVYIKQGDNLADRPVLPLFYEIIGDKGIVLSSGYKWKHQRRFALSTLRNFGLGKKSLEPSINLECGFLNEAISNEQGRPFDPRLLLNNAVSNVICVLVFGNRFDYSDHHFQTLLKHINEAIYLEGGICAQL-------YNMFPWLMQR-LPGSHKKVITLWKKVIDFIRQKVNEHKVDHDPLNPR--DYIDCFLAEMEKLKDDTAAG--FDVENLCICTLDLFVAGTETTSTTLYWGLLYMMKYPVIQAKVQEEIDRVVGGSRHPSVSDRDNMPYTNAVIHEIQRMGNIIPINVTRTTSEDIRIGKYSVPKGTMVTSNLTSVLFDESEWETPHSFNPGHFL----NAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEPSL 476          

Query:  247 PTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEE---IDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVS-DALYEEALIG 1611
            P  K LP VG L  ++ T  F  +  L K +G++F V  G R  ++L  Y+TVK A V+    +  R       L      I F +GE W+  R F L    DFG+GK  S E   +E  +L  E +   GK  D +  ++    NIIS  +   RF   + ++  +     + ++      ++ Y +       WL  ++    NR V+   + +   E+   I    +TL+ + +    +D FLI +   + S      F +  L      L  AG +TT T+L W  + M+KY  IQ +V EEI  +IG  R P  +DRK L YT AV+ EI R++++ PL+L HR  +D + NGY++ K   V   L +   DE  WEKP  FYPE FL  D  G  ++   +    F  G+R C GESLA+ME F+FFTS++Q +       VS DAL  + ++G
Sbjct:   67 PGPKPLPLVGNLLTLDLTRSFDTFFELSKTYGNIFQVFLGHRKTVVLVGYKTVKEALVNYAEVFGDREIGPGFKLKDEEHGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYIDPRFTEMVARANENVRVGGSFSMMIYNI-----FPWLGPFL---KNRAVVVKNITQNRAEKKKLITALLETLNPH-DPRGFVDSFLIHKLSDEKSGKKDSYFHEENLMLTVANLFAAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGG-RQPVVDDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFL--DEKG--QFVKRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDALDLKGIVG 512          

Query:  163 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCL-QLLFYTLPLFDKMTWLCDWILRRTNRK--VLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1554
            + C FLL +      T     PK     P    LP +G L+ I+   I    E+L +K+GSV +V    +  +ILN Y+ VK  ++  G N + R ++     ++G   +    G  W+ QR F L    +FG+GK         EC YL + +   NG+  D   L++    N+I   +   RF   +  ++T+ N   +A+     +   L+ + P   ++       L   ++K   L++ V    +E + EHR   D  S   D +D FL +  +LK  T +   F    L   +L+L +AG ETT+T+L WS L+M KY  IQ KV EEI  +IG  R P+ +DR ++ YT AV+ EI R  ++A L L   A+ D  +  Y +PK  +V  NL +  FDE  WE P  F P  FL  D  G  K+   +    F +GKR C GE LA+ME F+FFTS++Q F
Sbjct:   54 FACVFLLLSNYIQNKT-----PKNFP--PGPWPLPIIGNLYHIDFNKIHLEVEKLSEKYGSVVSVHLFGQRTVILNGYKQVKEVYIQQGDNVADRPELPMIHDIAGDNGLVAPSGYKWKQQRRFALSTLRNFGLGKKSLEPSINLECHYLNEAISNENGRPFDPHLLLNNAISNVICVLVFGNRFDYSDHHFQTLLNNINEAMYLDGTIWAQLYNSHPRIMRL-------LPGPHKKNITLWNKVIDFARERVKEHRVDYD-PSNPRDYVDCFLAEMEKLKDDTAAG--FDVENLCICTLDLFVAGTETTSTTLSWSLLYMIKYPEIQAKVQEEIDRVIGSSRQPSVSDRDNMPYTNAVIHEIQRFGNIAALNLPRAAVKDIQVGKYLIPKGTIVIGNLTSVLFDESEWETPHSFNPGHFL--DAEG--KFRRRDAFLPFSLGKRVCLGEQLARMELFLFFTSLLQHF 500          

Query:  247 PTEKGLPFVGVLHQI--ETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVD--KLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1554
            P  K LP +G +H I  + P   Y E L KK+G +F V+ G + +++L  Y+TVK A V+    +S R  V   L +     I F  GE W++ R F L    DFG+G+    +   +EC +L+++ ++  GK  D + +++    NII   +   RF  ++ K+  + +L  + L+      ++ Y +     M WL        ++ V  +A +  + ++E   +H++ LD+N +  +L+D FL+KQ + K   G++  F D  L  L   L +AG+ETT+TS+ W  L M KY  IQ+ V  EI  +IG+ R P T  RK + YT AV+ EI R  ++ P+ L H    D +  GY++PK   V   L +  +D+  +EKPKEFYP+ FL ++ N    +  NE    F  GKR CAGE+LAKME F+FFTS++Q F
Sbjct:   36 PGPKPLPIIGNIHNINLKRPYLTYLE-LWKKYGPIFRVQIGSQKMVVLCGYETVKDALVNYAEEFSERPVVPIFLDVVKEYGIIFSHGENWKVMRRFTLSTLRDFGMGRRTIEDRINEECDFLVEQFKSFKGKPFDNTMIMNAAVANIIVSIVLGHRFDYQDPKFLRLMSLINENLRLTGSPTVMLYNV-FPSVMRWLPG-----NHQTVGKNAAENQRFIRETFIKHKEKLDVNDQ-RNLVDAFLVKQQEKK---GNAVYFHDDNLTMLVSNLFVAGMETTSTSVRWGLLLMMKYPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTFVIPLLTSVLYDQTRFEKPKEFYPQHFLDSEGN----FVKNEAFLPFSAGKRSCAGENLAKMELFLFFTSLLQNF 459          

Query:  247 PTEKGLPFVGVLHQI--ETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVD--KLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1554
            P  K LP +G +H I  + P   Y E L KK+G +F V+ G + +++L  Y+TVK A V+    +S R  V   L +     I F  GE W++ R F L    DFG+G+    +   +EC +L+++ ++  GK  D + +++    NII   +   RF  ++ K+  + +L  + L+      ++ Y +     M WL        ++ V  +A +  + ++E   +H++ LD+N +  +L+D FL+KQ + K   G++  F D  L  L   L +AG+ETT+TS+ W  L M KY  IQ+ V  EI  +IG+ R P T  RK + YT AV+ EI R  ++ P+ L H    D +  GY++PK   V   L +  +D+  +EKPKEFYP+ FL ++ N    +  NE    F  GKR CAGE+LA+ME F+FFTS++Q F
Sbjct:   36 PGPKPLPIIGNIHNINLKRPYLTYLE-LWKKYGPIFRVQIGSQKMVVLCGYETVKDALVNYAEEFSERPVVPIFLDVVKEYGIIFSHGENWKVMRRFTLSTLRDFGMGRRTIEDRINEECDFLVEQFKSFKGKPFDNTMIMNAAVANIIVSIVLGHRFDYQDPKFLRLMSLINENLRLTGSPTVMLYNV-FPSVMRWLPG-----NHQTVGKNAAENQRFIRETFIKHKEKLDVNDQ-RNLVDAFLVKQQEKK---GNAVYFHDDNLTMLVSNLFVAGMETTSTSVRWGLLLMMKYPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTFVIPLLTSVLYDQTRFEKPKEFYPQHFLDSEGN----FVKNEAFLPFSAGKRSCAGENLARMELFLFFTSLLQNF 459          

Query:  247 PTEKGLPFVGVLHQI--ETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVD--KLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1554
            P  K LP +G +H I  + P   Y E L KK+G +F V+ G + +++L  Y+TVK A V+    +S R  V   L +     I F  GE W++ R F L    DFG+G+    +   +EC +L+++ ++  GK  D + +++    NII   +   RF  ++ K+  + +L  + L+      ++ Y +     M WL        ++ V  +A +  + ++E   +H++ LD+N +  +L+D FL+KQ + K   G++  F D  L  L   L +AG+ETT+TS+ W  L M KY  IQ+ V  EI  +IG+ R P T  RK + YT AV+ EI R  ++ P+ L H    D +  GY++PK   V   L +  +D+  +EKPKEFYP+ FL ++ N    +  NE    F  GKR CAGE+LA+ME F+FFTS++Q F
Sbjct:   36 PGPKPLPIIGNIHNINLKRPYLTYLE-LWKKYGPIFRVQIGSQKMVVLCGYETVKDALVNYAEEFSERPVVPIFLDVVKEYGIIFSHGENWKVMRRFTLSTLRDFGMGRRTIEDRINEECDFLVEQFKSFKGKPFDNTMIMNAAVANIIVSIVLGHRFDYQDPKFLRLMSLINENLRLTGSPTVMLYNV-FPSVMRWLPG-----NHQTVGKNAAENQRFIRETFIKHKEKLDVNDQ-RNLVDAFLVKQQEKK---GNAVYFHDDNLTMLVSNLFVAGMETTSTSVRWGLLLMMKYPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTFVIPLLTSVLYDQTRFEKPKEFYPQHFLDSEGN----FVKNEAFLPFSAGKRSCAGENLARMELFLFFTSLLQNF 459          

Query:  247 PTEKGLPFVGVLHQI--ETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVD--KLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1554
            P  K LP +G +H I  + P   Y E L KK+GS+F+V+ G + +++L  Y+TVK A V+    +S R  +   L       + F  GE W++ R F L    DFG+G+    +   +EC +L+++ ++  GK  D + +++    NII   +   RF  ++  +  + +L  + ++     + + Y +     M WL        ++ V  +A +  + ++E   ++R  LD+N +  +L+D FL+KQ +     G++  F D  L  L   L +AG+ETT+TS+ W  L M K+  IQ+ V  EI  +IG+ R P T  RK + YT AV+ EI R  ++ P+ L H    D +  GY++PK   V   L +  +D+  +EKPKEFYP+ FL ++ N    +  NE    F  GKR CAGE+LA+ME F+FFTS++Q F
Sbjct:   36 PGPKPLPIIGNIHNINLKRPYLTYLE-LWKKYGSIFSVQIGSQKMVVLCGYETVKDALVNYAEEFSERPVIPIFLDAVKEYGVIFSHGENWKVMRRFTLSTLRDFGMGRRTIEDRINEECDFLVEQFKSFKGKPFDNTMIMNAAVANIIVSIVLGHRFDYQDPIFLRLMSLINENVRLTGSPKAMLYNV-FPSVMRWLPG-----NHQTVGKNAAEYHRFIRETFTKYRDKLDINDQ-RNLVDAFLVKQQE---KNGNAVYFHDDNLTVLVSNLFVAGMETTSTSVRWGLLLMMKFPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTFVIPLLTSVLYDQTRFEKPKEFYPQHFLDSEGN----FVKNEAFLPFSAGKRSCAGENLARMELFLFFTSLLQNF 459          

Query:  247 PTEKGLPFVGVLHQI--ETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVD--KLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1554
            P  K LP +G +H I  + P   Y E L KK+G +F V+ G + +++L  Y+TVK A V+    +S R  V   L +     I F  GE W++ R F L    DFG+G+    +   +EC +L+++ ++  GK  D + +++    NII   +   RF  ++  +  + +L  + ++     + + Y +     M WL        ++ V  +A +  + ++E   ++R  LD+N +  +L+D FL+KQ +     G++  F D  L  L   L +AG+ETT+TS+ W  L M K+  IQ+ V  EI  +IG+ R P T  RK + YT AV+ EI R  ++ P+ L H    D +  GY++PK   V   L +  +D+  +EKPKEFYP+ FL ++ N    +  NE    F  GKR CAGE+LA+ME F+FFTS++Q F
Sbjct:   36 PGPKPLPIIGNIHNINLKRPYLTYLE-LWKKYGPIFRVQIGSQKMVVLCGYETVKDALVNYAEEFSERPVVPIFLDVVKEYGIIFSHGENWKVMRRFTLSTLRDFGMGRRTIEDRINEECDFLVEQFKSFKGKPFDNTMIMNAAVANIIVSIVLGHRFDYQDPIFLRLMSLINENVRLTGSPKAMLYNV-FPSVMRWLPG-----NHQTVGKNAAEYHRFIRETFTKYRDKLDINDQ-RNLVDAFLVKQQE---KNGNAVYFHDDNLTVLVSNLFVAGMETTSTSVRWGLLLMMKFPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTFVIPLLTSVLYDQTRFEKPKEFYPQHFLDSEGN----FVKNEAFLPFSAGKRSCAGENLARMELFLFFTSLLQNF 459          

Query:  247 PTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVL-FDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSD 1584
            P  K LP +G L Q+ +  +     +L K++GSVF V  G R VI+L+ YQTVK A VD G  +SGR         +    IAF DGE W+I R F +++  +FG+GK    E   +E  +L++ L  + GK  D   ++     NII   +   RF   +++  TI +      K         Y +        + DWI     R    F  +  L+   + EH+ +LD NS   D ID FL K  Q K    S   F    L   +  LL  G ET  T+L  +FL + KY  +Q +V EEI  ++G+ R PT  DR  + YT AV+ E+ R + V P+ L HR   D+   G+ +PK   V + L   H+D   ++ P+EF PE FL    + +  +  +     F  G+R C GE LA+ME FI+FTSI+Q F ++   D  D
Sbjct:   32 PGPKPLPILGNLLQLRSQDLLTSLTKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFINDNFKIMSSPWGEMYNI-----FPSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTKMAQEKQDPLS--HFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFL----DDNHSFKKSPAFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQPLVDPED 467          

Query:  199 WKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIET-PIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQ-SLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTW-LCDWILRRTNRKVLFDAVDKL---VQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVR 1563
            WK T      KG +  P    +PF+G   Q+ T   F+ +++L KK+GSVF V +G R V++L  ++ VK A VD   ++SGR ++        GY  +A  +GE W+I R F L V  +FG+GK    E  ++E  YL++EL  + G  +D +  +     N+I   +  KRF  ++ +++++  +  ++  +        Y       M W +  +   R N   L++ ++ L   +   +  +  + D  S   D ID FLIK HQ K+   +  +F    L   +L L  AG ET +++L + FL + KY  ++ K+HEEI  +IG  R P  +DR  + YT AV+ EI R++ + PL + H    D+   GY +PK   V+    +   D K +  P  FYP+ FL  D  G  ++  N+    F  GKR C GE+LA+ME F++FTSI+QRF +R
Sbjct:   24 WKRTS-----KGGKLPPGPTPIPFLGNFLQVRTDATFQSFQKLQKKYGSVFTVYFGPRPVVVLCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYG-LALSNGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHKVKGAPIDPTLYLSRTVSNVICSVVFGKRFDYQDQRFQSLMRMINESFVEMSKPWAQLY------DMYWKVMQYFPGRHN--YLYNLIEDLKDFIASRVKINEASFD-PSNPRDFIDCFLIKMHQDKSDPHT--EFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLLKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVTRDTHFRGYLLPKGTDVYPLFGSVLKDPKYFRYPDAFYPQHFL--DEQG--RFKKNDAFVVFSSGKRICVGEALARMELFLYFTSILQRFSLR 463          

Query:  247 PTEKGLPFVGVLHQIET-PIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVS-QSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1560
            P  + LPF+G L Q++   +   + +L +K+G VF V  G R V++L    T++ A V+    +SGR  V+    ++ GY  I F  GE W+  R F L    DFG+GK    E  ++E   L++EL+   G  ++ +        NII   +  +RF  K+ ++  + NL  Q       L    + L  F  +        R+ ++ +    +   +   +++HR TLD  S   D ID +L++  + K++  +  +F    L    L L  AG ETT+T+L +SFL M KY  + +KV +EI  +IG  R PT +DR  + YT AV+ EI R + +AP+ L H+   D+   GY +PK+  V+  L +   D + +E+P  F PE FL  D NG +K   NE    F  GKR C GE +A+ E F+FFT+I+Q F +
Sbjct:   33 PGPRPLPFLGNLLQMDRRGLLSSFIQLQEKYGDVFTVHLGPRPVVMLCGTDTIREALVNQAEAFSGRGTVAVLDPIVQGYGVI-FSSGERWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYKGAPLNPTFYFQCIVANIICSIVFGERFDYKDHQFLHLLNLIYQTFSLMSSLSSQVFEL--FSAILKYFPGAHRQISKNL--QEILDYIGHSVEKHRATLD-PSAPRDFIDTYLLRMEKEKSNHHT--EFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFTDLAPIGLPHKVTKDTLFRGYLIPKNTEVYPILSSALHDPRYFEQPDSFNPEHFL--DANGALK--TNEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSL 460          

Query:  301 IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQS-LLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKL--VQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1560
            + + +  L +KHG VF V  G R V++L   QT++ A V++   +SGR  ++ + L+M  Y  I F  GE W+  R F L    +FG+GK    E  ++E   L++EL+   G  +D +      T NII   +  +RF   ++++  + NL  Q         L  ++  +F+  + L  +     +R++  +  + L  +   +++HR TLD  SE  D ID +L++  + K++  +  +F    L    L L  AG ETT+T+L   FL M  Y  + +KV +EI  +IG  R PT +DR  + YT AV+ EI R S + P    HR   D+   GY +PK+  V+  L +   D + +E+P  F P+ FL  D NG +K   +E    F  GKR C GES+A+ E F+FFTSI+Q F V
Sbjct:   51 LLKCFIHLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVNNAEAFSGRGTIAAAQLVMQDYG-IFFSSGERWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGAPLDPTFFFQCVTANIICSIVFGERFDYTDEQFLRLLNLMYQIYS-----LLRSFSCQMFELFSGLLKY-FPGVHRQIAKNQQEILNFITHRVEKHRATLD-PSEPRDFIDTYLLRMEKEKSNHNT--EFHHQNLMMSVLSLFFAGTETTSTTLCCGFLLMLMYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDIVPTGAPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDHFL--DANGALK--KSEAFLPFSTGKRICLGESIARNELFLFFTSILQNFSV 459          

Query:  301 IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQS-LLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFD-KMTWLCDWILR---RTNRKVLFDAVDKL--VQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1560
            + + + +L +KHG VF V  G R V++L   QT++ A VD    +SGR  ++ + L+M  Y  I F  G+ W+  R F L    +FG+GK    E  ++E   L++EL+   G  +D + L    T NII   +  +RF   +D++  + NL          +  +F  L  F  +M  L    L+     +R+++    + L  +   +++H+ TLD  S   D ID +L++  + K++  +  +F    L    L L  AG ETT+ +L +  L M KY  + +KV +EI  +IG  R PT +DR  + YT AV+ EI R S + P+ L H+ + D+   GY +PK+  V+  L +   D + +E+P +F PE FL  D NG +K    E    F  GKR C GES+A+ E FIFFT+I+Q F V
Sbjct:   51 LLKCFIQLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVDHAEAFSGRGTIAAAQLVMQDYG-IFFASGQRWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGVPLDPTFLFQCITANIICSIVFGERFDYTDDQFLHLLNL----------MYKIFSLLSSFSGQMFELFSGFLKYFPGVHRQIVKKQQELLDYIAHSVEKHKATLD-PSAPRDYIDTYLLRMEKEKSNHNT--EFHHQNLMMSVLSLFFAGTETTSATLHYGVLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDLVPIGLPHKVIKDTLFRGYLLPKNTEVYPVLSSALHDPQYFEQPDKFNPEHFL--DANGALKKC--EAFLPFSTGKRICLGESIARNELFIFFTTILQNFSV 459          

Query:  199 WKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIET-PIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQ-SLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLP---LFDKMTWLCDWILRRTNRKVLFDAVDKL---VQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVR 1563
            WK T R     G +  P    +PF+G L Q+     F+ + +L KK+GSVF V +G R V+IL  ++ VK A VD   ++SGR ++        GY  +A  +GE W+I R F L V  +FG+GK    E  ++E  YL++EL  + G  +D +  +     N+I   +  KRF  ++ +++++  +  ++  +         ++P   L+D    +  +   R NR  L++ +++L   +   +  +  + D  S   D ID FLIK +Q K+   S  +F    L   +L L  AG ET +++L + FL + KY  ++ K+HEEI  +IG  R P  +DR  + YT AV+ EI R++ + PL + H  + D+   GY++PK   V+  + +   D K +  P+ FYP+ FL  D  G  ++  N+   AF  GKR C GE+LA+ME F++FTSI+QRF +R
Sbjct:   24 WKRTSR-----GGKLPPGPTPIPFLGNLLQVRIDATFQSFLKLQKKYGSVFTVYFGPRPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYG-LALSNGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHKVKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMINESFVE--------MSMPWAQLYDMYWGVIQYFPGRHNR--LYNLIEELKDFIASRVKINEASFD-PSNPRDFIDCFLIKMYQDKSDPHS--EFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVYPLIGSVLKDPKYFRYPEAFYPQHFL--DEQG--RFKKNDAFVAFSSGKRICVGEALARMELFLYFTSILQRFSLR 463          

Query:  247 PTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVL-FDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSD 1584
            P  K LP +G L Q+ +  +     +L K++GSVF V  G R VI+L+ YQTVK A VD G  +SGR         +    IAF DGE W+I R F +++  +FG+GK    E   +E  +L++ L  + GK  D   ++     NII   +   RF   +++  TI +      K         Y +        + DWI     R    F  +  L+   + EH+ +LD NS   D ID FL K  Q K    S   F    L   +  LL  G ET  T+L  +FL + KY  +Q +V EEI  ++G+ R PT  DR  + YT AV+ E+ R + V P+ L HR   D+   G+ +PK   V + L   H+D   ++ P+EF PE FL    + +  +  +     F  G+R C GE LA+ME FI+FTSI+Q F ++   D  D
Sbjct:   32 PGPKPLPILGNLLQLRSQDLLTSLTKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFINDNFKIMSSPWGEMYNI-----FPSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTKMAQEKQDPLS--HFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFL----DDNHSFKKSPAFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQPLVDPED 467          

Query:  247 PTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLP---LFDKMTWLCDWILRRTNRKVL--FDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1560
            P  K LP +G L Q+ +  +     +L K +GSVF V  G R VI+L+ YQTVK A VD G  +SGR         +    IAF DGE W+I R F +++  +FG+GK    E   +E  +L+D L    GK  D   ++     NII   I   RF   +++  TI +         D  Q++  + P   +++    L DW+    +R+V   F  +  L+   + EH+ +LD NS   D ID FL K  Q K    S   F    L   +  LL  G ET  T+L  +FL + KY  +Q +V EEI  ++G+ R PT  DR  + YT AV+ E+ R + V P+ L HR + D+   G+ +PK   V + L   H+D   ++ P+EF PE FL    + +  +  +     F  G+R C GE LA+ME FI+ TSI+Q F +
Sbjct:   32 PGPKPLPILGNLLQLRSQDLLTSLTKLSKDYGSVFTVYLGPRRVIVLSGYQTVKEALVDKGEEFSGRGSYPIFFNFTKGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLDVLRKTEGKPFDPVFILSRSVSNIICSVIFGSRFDYDDERLLTIIHF------INDNFQIM--SSPWGEMYNIFPSLLDWV-PGPHRRVFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTKMVQEKQDPLS--HFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDCVVGRSRMPTLEDRASMPYTDAVIHEVQRFADVIPMNLPHRVIRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFL----DANQSFKKSPAFMPFSAGRRLCLGEPLARMELFIYLTSILQNFTL 459          

Query:  229 KGLRRIPT-EKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVL--FDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVR 1563
            KG  R+P   + LPF+G L Q+ +  +     +L K+ G+V+ V  G R V++L+ YQ VK A VD    +SGR         +    IAF +G+ W+  R + L++  +FG+GK    E   +E  +L++EL    GK  D + ++     NII   I   RF   +D+  TI +L  +  +         Y +        L DW+    +R++   +  +  L+   + EH+ +LD NS   D ID FL K  Q K     S  F D  L   +  LL  G ET  T+L  +F  + KY  +Q +V EEI  ++G+ER PT  DR ++ YT AV+ E+ R + + P++L HR   D++  G+ +P+   V + L   H+D   + KPKEF PE FL    + ++ +  +     F  G+R C GE+LA+ME F++ T+I+Q F ++
Sbjct:   25 KGKGRLPPGPRALPFLGNLLQLRSQDMLTSLTKLSKEFGAVYTVYLGPRRVVVLSGYQAVKEALVDQAEEFSGRGDYPAFFNFTKGNGIAFSNGDRWKALRKYSLQILRNFGMGKRTIEERILEEGHFLLEELRKTQGKPFDPTFVVSRSVSNIICSVIFGSRFDYDDDRLLTIIHLINENFQIMSSPWGEMYNI-----FPNLLDWV-PGPHRRLFKNYGRMKNLIARSVREHQASLDPNSP-RDFIDCFLTKMAQEKQDP-LSHFFMD-TLLMTTHNLLFGGTETVGTTLRHAFRLLMKYPEVQVRVQEEIDRVVGRERLPTVEDRAEMPYTDAVIHEVQRFADIIPMSLPHRVTRDTNFRGFTIPRGTDVITLLNTVHYDPSQFLKPKEFNPEHFL----DANMSFKKSPAFMPFSAGRRLCLGEALARMELFLYLTAILQSFSLQ 460          

Query:  226 PKGLRRIPT-EKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQ-SLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQL-LFYTLPLFDKMTWLCDWILRRTNRKVL--FDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRF---SEDVSDALYEEALIGN 1614
            PK   R+P     LP +G L Q++   + R + RL +K+G VF V  G R V++L     ++ A VD    +SGR K++    +  GY  + F +GE W+  R F L    DFG+GK    E  ++E   L++EL    G  +D + L H  T NII   +  KRF  K+  +  + +L  Q+          +F   P F K           T+R++      ++  + + +++HR TLD  S   D ID +L++  + K+    S +F    L    L L  AG ETT+T+L + FL M KY  + ++V +EI  +IG  R P  +DR  + YT AV+ EI R+  + P  + H    D+   GY +PK+  VF  L +   D + +E P  F P  FL  D NG +K   NE    F +GKR C GE +A+ E F+FFT+I+Q F +      ED+ D    E+ +GN
Sbjct:   24 PKAHGRLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYG-VIFANGERWRALRRFSLATMRDFGMGKRSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFELFPGFLKH-------FPGTHRQIYRNLQEINTFIGQSVEKHRATLD-PSNPRDFIDVYLLRMEKDKSD--PSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFL--DANGALK--RNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDI-DLTPRESGVGN 479          

Query:  196 FWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVRGSKIKNYIFTK 1662
            F+ F +R  IPKGL+  P E GLP +G++H+I+ P+  Y  +L KKHG +F ++ GMRDV+IL++Y  +K A VDDG N+SGRW++    L++  + I F DG+ W  QR FVLKV  DFG+GKS S ++ + EC +L++ELE+L GK +D S +I +YT NIISKFI NKRF R+  K   I  +  + +K+KD +QLL    P  D     C+ I+  T++   F  +    +EEIDEH KT+D NSEGEDL+DRFLIKQ+QLK        F D+QL R SLEL  AG ETT+T+L WSFLFMSK+  IQQKVH EI+ IIGKER PT ND+K +NYTQAVMDEIFR+SSVAPLAL+HR +ND++I+GY++PK+ L+F NLYACHFD  +WEKP  FYPE FL+ D NG++KYT  + L  F +GKR+C GESLA+ME FIFFTSI+QRF V+  +++++  YEEAL+G +GI+RGS + ++IFTK
Sbjct:   17 FYGFQKRNSIPKGLKETPIEYGLPILGIIHKIKEPMHNYLLKLSKKHGPIFRIKLGMRDVLILSNYDIIKKALVDDGQNFSGRWRMKLISLITHDSGIIFKDGQDWSTQRSFVLKVLRDFGLGKSKSVDLVQNECSFLLEELESLEGKIIDFSKIIPIYTANIISKFIMNKRFERENPKIARIEKMLSEEIKKKDIIQLLHIMFPKCDTSGLFCELIINFTSKWKEFLEIQNYFKEEIDEHLKTIDFNSEGEDLMDRFLIKQNQLKQQNIDVGSFNDWQLIRSSLELFYAGYETTSTTLCWSFLFMSKHQDIQQKVHNEIIEIIGKERLPTMNDKKSMNYTQAVMDEIFRMSSVAPLALIHRTLNDANIDGYFIPKNTLIFPNLYACHFDRDIWEKPMIFYPEHFLTEDDNGNLKYTPRDELILFSIGKRQCLGESLARMEFFIFFTSILQRFRVKLVKELNEKEYEEALLGKDGIIRGSIVNDFIFTK 505          

Query:  178 LLGAAIFW----KFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVRGSKIKNYIF 1656
            + G  I W    +  +R  IP GL+  P E G P +G++ +I+ P+  Y   L +KHG +F +R GMRDV+IL +YQT++ A VDD   +SGRWK+    +++  + I F DG +W  QR F+LKV  DFG+GKS+S +I + ECL+L++EL++L G+ +D S +I +YT NIISKFI NKRF R + + K I     Q  KQ D +Q L    P+FDK T +  + L  T++  LF  V+++  +EI+EH+  LD NSEG+DLIDRFL++Q++L  STG  + FTD QL  ++ E+  AG ETT+T+L WS LFMS+Y  IQ+KV+EEI+N+IG+ER PT ND+K LNYTQAVMDEI R+SSVAPL + HR  ND+S++ Y++PK++LVF+N YACH D  +W KP EFYPE FL    N ++KY+  E L  FG+GKR+C GESLA+ME FIFF SI+QR++V FSE++SD+L+EE L GNEGI+R SKIKN+IF
Sbjct:    7 IFGLFIIWYCFSRVFKRRSIPNGLKETPIEYGWPILGIIPKIKGPMQNYLLELSRKHGPIFRIRLGMRDVVILGNYQTIRKALVDDAQIFSGRWKMKLVSVVTHDSGIVFKDGPVWSTQRSFILKVLRDFGMGKSISQDIVQGECLFLLNELDSLQGEIIDFSKIIPIYTANIISKFIMNKRFDRSDPRIKFIEYAIFQTSKQSDIVQRLHLMFPIFDKSTIISKFNLWITSKLQLFSKVERVFHDEIEEHKTNLDYNSEGDDLIDRFLLEQNRLSQSTGIVESFTDKQLIFMTFEMFGAGYETTSTTLGWSMLFMSRYKDIQKKVYEEILNVIGEERMPTMNDKKSLNYTQAVMDEILRLSSVAPLGIFHRTFNDTSVDNYFIPKNSLVFANYYACHTDPDIWLKPVEFYPEHFLIKCENDELKYSPREELIPFGIGKRQCIGESLARMEYFIFFVSILQRYQVDFSENISDSLFEETLRGNEGIIRYSKIKNFIF 503          

Query:  163 YLCTFL--LGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLH--QIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVL--FDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDA 1587
            ++ TFL  L    FW   RR   P G R       LP +G LH   ++ P +R Y +L K +G VF+V+ G++ +++++ Y+TVK A V+    ++ R K+     ++G   I F  GE W++ R F L    DFG+GK    +   +E  YL+D + +  GK  D S +IH    NII   +  KRF  K+ ++  + +L  ++++      +  Y   +F  + +L      R N+ +L   +     VQ    EH KTLD N +   LID FL+KQ + K++T     F +  L  L   L  AG+ETT T+L WSFL M KY  IQ+KV EEI  +IG    P    R  + YT AV+ EI R +++ PL L H    D ++ GY++PK   V   L +   D+  WEKP +FYPE FL  D  G  ++   +    F  G+R CAGE+LAKME F+FFTS++QRF       VS +
Sbjct:   12 FILTFLSILKMGHFWNNHRRKNFPPGPR------ALPIIGSLHLFDLKRP-YRTYLQLSKLYGPVFSVQMGLKKIVVISGYETVKEALVNQADAFAERPKIPIFQDLTGGNGIIFAHGENWKVMRRFTLTTLRDFGMGKRAIEDRIVEEYGYLVDNIGSQEGKPFDASKIIHAAVANIIVSILLGKRFDYKDSRFVRLLHLTNESMRLAGKPLVTMYN--IFPYLGFLL-----RANKTLLQIKEEFHAYVQVTFVEHLKTLDKNDQ-RSLIDAFLVKQQEEKSTTNG--YFHNGNLLNLVSNLFTAGVETTATTLNWSFLLMLKYPEIQRKVQEEIEQVIGSNA-PRIEHRTHMPYTDAVIHEIQRFANILPLDLPHETTEDVTLRGYFIPKGTYVIPLLTSVLQDKSQWEKPDKFYPEHFL--DAKG--RFVKKDAFMPFSAGRRICAGETLAKMELFLFFTSLLQRFTFHPPPGVSTS 470          

Query:  163 YLCTFL--LGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLH--QIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVL--FDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDA 1587
            ++ TFL  L    FW   RR   P G R       LP +G LH   ++ P +R Y++L K +G VF+V+ G R +++++ Y+TVK A V++   +S R K+     ++    + F  GE W++ R F L    DFG+GK    +   +E  YL D +    GK  D S +I+    NII   +  KRF  K+ ++  + +L  ++++      +  Y +  F  + +L      R N+ +L   D     V+    EH KTLD N +    ID FL+KQ + K++T     F +  L  L   L  AG+ET TT+L WSFL M KY  IQ+KV EEI  +IG +  P    R  + YT AV+ EI R +++ PL L H    D ++ GY++PK   +   L +   D+  WEKP  FYPE FL  D NG  K+   +    F  G+R CAGE+LAKME F+FFTS++QRF       VS +
Sbjct:   11 FILTFLSILKIGGFWNNHRRKNFPPGPR------ALPIIGNLHLFDLKRP-YRTYQQLSKVYGPVFSVQMGQRKIVVISGYETVKEALVNNADAFSERPKIPIFDDLTKGNGVVFAHGENWKVMRRFTLTTLRDFGMGKRAIEDRIVEEYGYLADTIGAQEGKPFDASKIINAAVANIIVSILLGKRFDYKDPRFARLLHLTNESMRLAGKPLVTMYNI--FPHLGFLL-----RANKTLLQNRDEFHAYVKVTFLEHLKTLDRNDQ-RSFIDAFLVKQQEEKSTTNG--YFHNGNLLSLVSNLFTAGVETITTTLNWSFLLMLKYPEIQRKVQEEIEQVIGSKP-PRIEHRTQMPYTDAVIHEIQRFANILPLDLPHETAADVTLKGYFIPKGTYIIPLLTSVLKDKSQWEKPDMFYPEHFL--DANG--KFVKRDAFMPFSAGRRICAGETLAKMELFLFFTSLLQRFTFHPPPGVSTS 469          

Query:  175 FLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLH--QIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLF--DAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVS 1581
            ++L    FW   R    P G R       LP +G LH   ++ P +R Y +L K +G VF+V+ G+R +++++ Y+TVK A V+    +S R K+     ++    + F  GE W++ R F L    DFG+GK V  +   +E  +L D +E+  GK  D S +I+    NII   +  KRF  K+ ++  + +L  ++++      +  Y +  F  + +L      R N+ +L   D     VQ    EH KTLD N +    ID FL+KQ + K++T     F +  L  L   L  AG+ET +T+L W FL M KY  IQ+KV EEI  +IG    P    R  + YT AV+ EI R +++ PL L H    D ++ GY++PK   +   L +   D+  WEKP  FYPE FL  D NG  K+   +    F  G+R CAGE+LAKME F+FFTS++QRF       VS
Sbjct:   14 YILKVGGFWNNHRNKNFPPGPR------PLPIIGNLHLFDLKRP-YRTYLQLSKIYGPVFSVQMGLRKIVVISGYETVKEALVNQADAFSERPKIPVFEDLTRGNGVVFAHGENWKVMRRFTLTTLRDFGMGKRVIEDRIVEEYRHLADIIESQEGKPFDASKMINAAVANIIVSILLGKRFDYKDSRFVRLQDLTNESMRLAGKPLVTVYNI--FPHLGFLL-----RANKNLLRNRDEFHAYVQVTFVEHLKTLDKNDQ-RSFIDAFLVKQQEEKSTTNG--YFHNGNLLSLVSNLFTAGVETISTTLNWGFLLMLKYPEIQRKVQEEIERVIGSNP-PRIEHRTQMPYTDAVIHEIQRFANILPLDLPHETAADVTLKGYFIPKGTYIIPLLASVLQDKSQWEKPDMFYPEHFL--DANG--KFVKKDAFMPFSAGRRICAGETLAKMELFLFFTSLLQRFTFHPPPGVS 464          

Query:  247 PTEKGLPFVGVLHQ-IETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQS-LLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKY-KTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFD--AVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVRGSKIKNYI 1653
            P  K LPF+G L Q I+ P+   Y R + K+G + ++  G    I+LN  Q  K AFV +G+ +SGR  +  +  L  GY  +       W+ QR F L    DFG+GK    E   +E  YLI E+    GK    S  I     NII   I   RF   + ++ K +  L          L  +F  LP                ++KV  +  A+ + + E ++EHRKTLD      D ID +L++   +K  +     F    + R   +L  AG ETT  +L W  ++M     +Q++ HEEIV ++G +RFP+TNDR  L YT A + EI R +++APL ++H     + + G+++P    +  NL A   D++ W+ P  F PE FL  D  G  ++  N++  AF +G R C GE+LA+ E FIFFTS++Q+    +    S         G  GIVR +   N I
Sbjct:   41 PGPKPLPFLGNLPQFIKDPM--TYIRSMPKYGELCSMYLGRNPTIVLNTMQIAKEAFVQNGAVFSGRPSMPLTRWLNKGYGIVMAPYSNSWRQQRRFALHTLRDFGLGKKTVEERVAEEARYLIKEMLKEEGKPFYPSHPIMNAVSNIICSIIFGDRFDYDDKRFAKLLDILNDNVRLVGSPLAQIFNLLPFMKHFPG--------PHQKVWENDVALKEFIFEVVEEHRKTLD-QENLRDFIDAYLVEM--MKQESNEDSTFHKENMLRSITDLFGAGTETTANTLRWGLIYMMDNPDVQERCHEEIVRVLGFDRFPSTNDRSHLPYTYATVHEIQRNANIAPLGVMHTTTQPTQLQGFHIPAGTDIVPNLTAILNDQEHWKYPDMFNPENFL--DEKG--QFCKNDSFLAFSLGPRVCLGETLARTELFIFFTSLLQQLRFSWPPGASSPNKR----GTAGIVRTTLPFNTI 493          

Query:  247 PTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQ-SLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALK-QKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVRGSKIKNYI 1653
            P  K + FVG L Q       Y  R + K+G + ++  G +  I+LN  Q  K AFV +G+ +SGR  +     +  GY  +    G  W+ QR F L    DFG+GK    E   +E  YLI E+    GK       I     NII   +   RF   + ++  +  +  + ++     +  +F  +P    +      I  R N     D+++K + +EI+EHRKTLD  +   D ID +L++  + + S   S  F +  + R +++L  AG ETT  +L W  ++M ++  +Q++ HEEIV ++G + FP+ +DR  L YT A + EI R +++ PL +VH+    + + GY++P    + SNL A   D+  W+ P  F PE FL  D  G  ++  N++   F +G R C GE+LA+ E FIFFTS++Q+ +  +    +  L  + ++   G+VR +   N I
Sbjct:   41 PGPKPMLFVGNLPQFMKDKMGYI-RSMPKYGEMCSMYLGRKPTIVLNSVQIAKEAFVQNGAVFSGRPSLPLIRWINKGYGIVMATYGNSWRQQRRFALHTLRDFGLGKKSVEERVAEEARYLIKEMLKQEGKPFYPIHPIMNAVSNIICSIVFGDRFEYDDRRFAELLEIINENIRFSGSPVAQIFNLVPFIKHLPGPQQKI--RQN----LDSLNKFIFDEIEEHRKTLDPENP-RDFIDSYLVEMKKQQGSNEDST-FHENNMVRSTIDLFGAGTETTANTLRWGLIYMMEHPDVQERCHEEIVRVLGFDCFPSMDDRAQLPYTLATVHEIQRYANIVPLGVVHQTTQPTKLRGYHIPAGTNIMSNLTAIMADKDHWKYPNTFNPENFL--DEKG--QFCKNDSFLPFSLGPRVCLGETLARTELFIFFTSLIQQLKFSWPPG-APPLNMDGIV---GVVRANLPFNTI 494          

Query:  259 GLPFVGVLHQIETPIFR-YYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGR-WKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLF---DAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVRGSKI 1641
             LPF+G +  I +P    Y  +L K + ++F++R G + +I+L  Y+ VK A V+   N+  R +      + SG   +   +G +W+ QR F L    +FG+GK        +E  +L+DE++   G+  D S L +    NII + +  +R+   +  ++ +     +A+  +  +    Y     +    +   +  R N  V+F   + + + +++ +D+H+  LD  S   D +D FLI++     S   +  F+D  L R +L+L LAG ETTTTSL W+ ++++K   IQ KV EEI  +IG+ R P   D+ ++ YT+AV+ EI R   + PL+    A  D+++ GY +PK   +   L++  FDE  WE P  F P+ FL  D  G  K+   +   AF  GKR C GE LA+ME F+FFT + Q+F  RFSE   + L  E ++G     R  KI
Sbjct:   43 ALPFLGNILDIASPQPHIYLTKLGKAYNNIFSMRIGQQKMILLTGYKMVKEALVNQTDNFVDRPYSPLAERIYSGNGGLFTSNGNLWKKQRRFALSTLRNFGLGKKTMELAICEESHFLLDEMDRHKGQAFDPSGLFNNAVSNIICQLVFGQRYDYADYDFQQMLKYTSEAIHLEGSIWGRLY-----ESFPNIMKHLPGRHN--VIFSNYEHISEFIKKNLDKHKANLD-PSNPRDYMDSFLIEKEN---SHDPADGFSDKNLVRCTLDLFLAGTETTTTSLGWALIYLAKNPEIQDKVQEEIDRVIGQSRQPGMADKPNMPYTEAVIHEILRRGDIVPLSGPRVAAKDTTLGGYAIPKGTTIMPILHSVLFDEDEWETPNSFNPQHFL--DKEG--KFVRRDAFLAFSAGKRVCLGEQLARMELFLFFTCLFQKF--RFSEVEGEELDTEGILGVTLTPRPYKI 491          

Query:  163 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVR-YGMRDVIILNDYQTVKSAFVDDGSNYSGR---------WKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRR---TNRKV--LFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDAL 1590
            + C FLL          R   P+     P    LPF+G LH I+T  I   +    +K+G++F+++ +G R V++ N Y+ VK  +V+ G +++ R         +K    +  SGYA         W+ QR F L    +FG+GK         EC YLI+ +    G   +   LI+    N+I   +   RF     +++ +  +  QA   +  +         + +M  +   I+RR    +++V  L+  V   V+ ++DEH+   D  S   D ID FL +  + K    +   F+   L   +++L +AG ETT+T+L W  L+M+KY  IQ KVH EI  ++G  R P+  DR +L YT AV+ EI R+ ++ P  L      D  I  Y +PK A VF NL +  FDE  WE PK F P  FL    N D  +   E    F  GKR C GE LA+ME F+FF+S++QRF  +  E V  +L
Sbjct:   19 FFCVFLLLVEYL-----RNKAPRNFP--PGPPTLPFIGNLHTIDTTRIHLQFIEFAEKYGNLFSIQIFGPRAVVV-NGYKLVKELYVNQGDHFADRPVFPLFHDIFKDKGLVASSGYA---------WKQQRRFALTTLRNFGLGKKSLEPSILLECRYLIEAMSNEQGNRFNPQFLINNAVSNVICVLVFGSRFEYSNSEFQDLLKMMNQAFYLEGTI---------WAQMYNMVPRIMRRLPGPHQRVIQLWGNVFNYVRAKVDEHKMDRDF-SNPRDYIDCFLEEMEKRKDDKAAD--FSIENLCFCAMDLFIAGTETTSTTLYWGLLYMTKYPEIQAKVHAEIDQVVGSSRQPSMMDRDNLPYTNAVIHEIQRMGNIIPFNLARATSKDVQIGEYTIPKGASVFGNLTSVLFDETEWETPKSFNPGHFL----NNDGSFRRREAFMPFSAGKRVCLGEQLARMELFLFFSSLLQRFTFKPPEGVEPSL 477          

Query:  238 RRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMS-GYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALK-QKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFD--AVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFE 1557
            R  P  K L FVG + Q          R + K+G +  V  G + +I+LN  Q  K AF+ +G+ +SGR  +  +  ++ GY  +    G  W+ QR F L    DFG+GK    E   +E  YLI E+    GK    S  I     NII   +   RF   + ++  +  +  + ++     +  +F  +P             R  ++K   +  ++ K + EE++EH+KTLD  +   D ID +L++  + +A+  S+  F +  + R +++L +AG ETT  +L W  ++M  +  +Q++ HEEIV ++G +RFP+ +DR  L YT A + EI R +++ PL ++H     + + GY++P+  +V  NL A   D+  W+ P  F PE FL  D  G  ++  N++   F +G R C GE+LA+ E FIFFTS++QR +
Sbjct:   38 RNPPGPKPLLFVGNMPQFMKDRMALI-RSMPKYGEMCTVYLGRKPMIVLNSVQIAKEAFIQNGTIFSGRPIMPVTRWINKGYGIVMATYGNSWRQQRRFALHTLRDFGLGKKSVEERVAEEARYLIKEMLKQEGKAFYPSHPIMNSVSNIICSIVFGDRFEYDDRRFAKLLEIINENIRFLGSPVSQVFNLIPFIKH--------FRGPHQKFWHNVHSLKKFIFEEMEEHKKTLDPENL-RDFIDAYLVEMIKQEANEDST--FHEENMVRSTIDLFIAGTETTANTLRWGLIYMMDHPDVQERCHEEIVRVLGFDRFPSMDDRAKLPYTLATVHEIQRYANIVPLGVLHETTQATKLRGYHLPQGTIVMPNLTAIMADKDHWKYPNTFNPENFL--DEKG--QFCKNDSFLPFSLGPRVCLGETLARTELFIFFTSLIQRLK 465          

Query:  166 LCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVG--VLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFID-GEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALK-QKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKV--LFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVS 1581
            +C   L      +    T  P G    P  K LP +G       + P     E L KK+G V  +  G   V++++ YQ VK   V+ G  ++ R        ++    IA    G+ W+ QR F L    +FG GK+   +    E  YLI+  +    ++ D   +++    NII   +   R+    ++++ + +L +  ++ Q + L +L    P   K+     W      +KV  +   +  L+++ + EHR T D ++   DLID +L   H  K     ++ FTD  L  L +EL + G+ETT+ +L W  LFM     IQ + HEEI  ++G +R P   DR+ L Y  AV+ EI R  ++ P  ++H    D   N Y  PK   V  NL +  +D+  W+ P +F P+ FL    + D +   ++    F  G   C GESLAKME F+FFTS++Q FE  +    S
Sbjct:   11 ICMVFLTVRAALQVVGSTICPVGFS--PGPKPLPLLGNITAFSCKNPHIGMQE-LAKKYGEVCTIMLGSTPVVLVSGYQAVKEVLVNRGHEFADRPITPLFTKLTHNIGIALAPYGDTWKQQRGFALSTLRNFGFGKATITDKISIEARYLIETFKQETSEF-DPKFILNSAVGNIICSLLNGIRYDYNNEQFQKLTHLLEHLVQLQAEPLVILCNVFPFLIKLPG--PW------QKVFHIHTKLQCLLKDIVSEHRATKDQHNP-RDLIDSYL--AHIDKEKDNPNRSFTDQTLILLLIELFIGGMETTSNTLCWGLLFMMMNPDIQARCHEEIDKVVGSQRPPCMKDRRSLPYLDAVIHEIQRFGNILPFGVLHPTSKDVQFNEYVFPKGTHVMVNLMSAFYDDIHWKTPHKFNPDNFL----DKDGQCIKSDAFLPFPAGPCVCFGESLAKMELFLFFTSLLQHFEFYWPNSAS 469          

Query:  268 FVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYAR-IAFID-GEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNL--------GQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAV---DKLVQEEIDEHRKTLDLNSEGE--DLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNE 1617
            F  V H   T +  +  +L + +G+V+ +R G  D+++LN+ +++K   +   ++++GR +      ++G  + IA  D   +W+ QR   L   H   +G + + EI + E   L+++L    G+  D+   I +   N+I       ++ + + ++  I           G  A++  DC    F  L LF    W           + L  AV   D++V  +I  H+     +   +  D + +F       + S       T+ ++    ++  +AG+ETT T +EW+  ++  +  +Q +++EE+   +     P+  DR  L Y  A + EI R+  VAPLA+ HRA+ DSS+ G+++ K + V +NL+A H D   W+ P  F P RFL   +    +      L  FG GKR C GESLAK E F+F   +++R  ++ +    D   + A++  +
Sbjct:   53 FGNVAHMARTDLHIHLTQLARTYGAVYCLRVGGEDIVVLNNVESIKEMLIKKSADFAGRPQTYAGGKITGGGKDIALGDYSAVWRRQRRAALSALH--CVGTARTEEIVQGEAQRLVEDLTQYIGRPTDIHTDISMRVCNVICSVAFGTKYDKHDTEFLDIHCCLDSLVRLWGSPAIRALDC----FPVLRLFPNPAW-----------RDLMAAVRKRDEVVWRQILLHKAKPSSSPSSDMTDFLLKFTRHSRNEEESEARGGILTEERVHLSIMDTFIAGVETTATLIEWALAYLVLHPEVQDQIYEEMEQKLQPGLGPSLADRDKLLYLDATIKEILRLCPVAPLAIPHRALRDSSVGGFFICKGSTVIANLWAAHRDHAHWDNPSVFQPGRFLGESLE---RRNPASLLLPFGAGKRVCLGESLAKAEIFLFLGHVLRRLRLQPAGSPPDLSGQLAIVPKQ 497          

Query:  247 PTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFID-GEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALK-QKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDK---LVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVS 1581
            P  K +PF+G +   + P     E + K++G V +V  G   ++ ++ YQ VK   V  G  ++ R     +  ++G   I F   G+ W   R F L    +FG+GKS   +  + E  +LI+  +   G   D    ++    NII   +  KR+   + +++   +L +  L+ Q   L  L    P      +L D+      ++++F ++ K    +++ I E   T D   +   LID +L    QL+     +  F++  L  L+L+L +AG ETT+T+L W  L+M  +  IQ + HEEI  I+G +R P   DR  L Y  AV+ EI R S++ P    H    D     Y +PK  ++  N+ +   DE  W+ P EF PE FL    + D K+   +    F  G R C GE+LAKME F+FF S++Q FE  + + VS
Sbjct:   55 PGPKVIPFLGNVSLFKKPDVALDE-VTKQYGEVCSVMVGKISMVFVSGYQAVKEVLVHQGHEFADRPNTPFNKKVNGGLGIIFAPYGKYWMQHRRFTLSTLRNFGLGKSSIEQTIQAEVGFLIEAFKQ-KGSAFDPHYDLNSAVGNIICSMVKGKRYEYSDKQFQDFLHLVENNLQLQSGLLGTLCNIFP------FLMDF---PGPQQIIFKSMAKSKQFIRDIISERHATRD-PIKPMCLIDAYL---SQLEKEDNPNSSFSEQSLIMLALDLFIAGAETTSTTLRWGLLYMMMHPEIQAQCHEEIDKIVGSDRLPCMEDRHSLPYLDAVIHEIQRFSNIVPFGAPHATTADVKFRQYLIPKGTIIMVNMKSVLSDENHWKTPYEFSPENFL----DEDGKFVKPDAFLPFSAGPRVCLGENLAKMELFLFFASLLQHFEFYWPDLVS 485          

Query:  316 ERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGR------WKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTV--NIISKFITNKRFSRKEDKYKTIGNLGQQALK-QKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKV--LFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVS 1581
            + L KK+G V  +  G   V++++ Y+ VK   V+ G  ++ R       K++Q++   G A   +  G+ W+ QR F L    +FG GK+   +    E  YLI   ET   +       ++L     NII   +   R+    ++++ + +L +  ++ Q + L +L    P   K+     W      +KV  +   +  L+ + + EHR T D ++   DLID +L +  + K +  SS  FT   L ++ +EL + GLETT+ +L W  LFM     IQ + H EI  ++G ER P   DR+ L Y  AV+ EI R  +V PL ++H    D   N Y  PK   V  NL +   D+  W+ P +F P+ FL    + D +   ++    F  G R C GESLAKME F+FFTS++Q FE  +   VS
Sbjct:   64 QELAKKYGEVCTIMLGSTPVVLVSGYEAVKEVLVNRGHEFADRPITPIFTKLTQNI---GIALAPY--GDPWKQQRRFALSTLRNFGFGKATIADKISIEAKYLI---ETFKQETSAFDPHLNLNNALGNIICCLLNRNRYDYDNEQFQKLTHLLEYLVQLQAEPLVILCNVFPFLLKLPG--PW------QKVFHIHSKLQCLLNDIVSEHRATKDQHNP-RDLIDSYLAQIDKEKDNPNSS--FTHQSLIQILIELFIGGLETTSNTLRWGLLFMMMNPDIQARCHGEIDRVVGSERPPCMTDRRSLPYLDAVIHEIQRFGNVLPLGVLHATSKDVQFNDYLFPKGTHVMVNLMSALHDDIHWKTPNKFNPDHFL----DKDGQCIQSDAFLPFSAGPRVCLGESLAKMEIFLFFTSLLQHFEFYWPNSVS 473          

Query:  247 PTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVS---QSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQ--ALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1554
            P  +GLP VG L Q++   +    ++L + +G +++V  G   V++L   + +K A V     +  R ++    +SL    Y  +    G  W+ +R F L +  +FG+G     E   +E  +L+  +E    K  D    I+    N+I       R+      +  + ++  +   L   D  Q+ F + P+   + +      R    KV+ +A    +Q  I+EH     +  E  D +D F+ K+  ++ S      F+D  L   +  L +AG ETT+ +L+W  L M  Y  +Q++V EEI  ++G  R P   DR  + YT A + EI R +++ P+A  H    D+ + GY++PK   V + +++   ++ +WE P++F P  FL  DI+G+  Y  N+ +    +G R C G++LA+ME F+FFT+++QRF
Sbjct:   42 PGPRGLPLVGNLFQLDLKALPASLDKLSETYGPIYSVSLGQTRVVVLVGNEIIKEALVTQAEMFIDRPEIPVFKKSL--GNYEGLLLSHGWQWRARRRFTLMMLRNFGMGTKSIEEKIAEEAEFLVRAIENKQEKPFDAHSEINKSAANVICSITFGDRYDWNNKTFVKLMDIITENVELSGNDWSQI-FNSFPV---LKYFPGPHQRINKNKVVLNA---FIQARIEEH-DMARIQGEPRDYLDAFIDKR--IEDSMNPDTAFSDIALINTTANLFVAGSETTSATLKWGILLMLTYPKVQEQVQEEIDRVVGSNRRPACADRACMPYTNATVHEIQRYANILPMAFPHATTCDTKLRGYFLPKGTQVIALIHSALREKSLWEAPEQFNPGHFL--DIDGNF-YNRNDFMAFSAVGPRICLGKNLARMEVFLFFTALLQRF 468          

Query: 1207 LNYTQAVMDEIFRVSSVAPLALVHRAM--NDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1560
            + YT  V+ E  R     P+ +V   +  N      Y  PK A++   LY    D +V+E P EF PER+    + G     A +N   FG G   C G++       I F +++ +F +
Sbjct:  386 MKYTNMVIKETLRYRP--PVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERW----VEGSKASEAKKNWLVFGCGPHVCLGQTY----VMITFAALLGKFAL 495          

Query:  322 LIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKV-SQSLLMSGYARIAFID-GEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAV---DKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSK--QFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFS 1569
            L K +G VF ++ G   ++++N  +  + A V   ++++GR  + + SL+      IAF D G +W+ QR         FG G     E    E   LI  L  + G+  +  D ++L  +NII  F+   R+   + ++ T+ +  +Q ++        F    L D   WL    L     + + +A    D ++Q++  EH  T + +    DL D  L      KAS   S     T+  +     ++  AGLETT TS+ WS +++ +   +Q+++H++I  ++G++R P  +DR++L   +A + E+ R SS+ PL   H    D+ + GY VPKD +V  N++  H D + W  P EF P RFL  D  G     A  +   F  G+R C  ESL KM+ F+F + ++ +F  RFS
Sbjct:   15 LAKSYGEVFRLKVGSHRIVVVNSIEAAREALVRRANDFAGRPMLYTASLISRNGTDIAFGDFGPLWKQQRKIAHSALRMFGSGLKPLEEKITVEADELIKRLSLVEGRAHNPKDDVNLAVLNIICSFVFGSRYDMDDPEFHTVVDYTEQFVQG-------FRAASLVDYFPWLRH--LPNKGLRQIKEACQNRDVVLQKKYQEHLVTYE-HGVIRDLTDALLSAN---KASQEESAYLPMTEDHIIMTMNDIFSAGLETTATSILWSLVYLIRNPKVQEQLHQQIDEVVGRDRAPELSDRENLPLIEATIAEVLRSSSLVPLLFPHSTTTDTHLRGYEVPKDTIVLFNVWNMHHDPQRWSNPDEFDPTRFL--DDKGKFICPATLSYLPFSAGRRVCLAESLGKMQLFLFISRLLHKF--RFS 420          

Query:  247 PTEKGLPFVGVLHQIETPIFRY-YERLIKKHGSVFAVR-YGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMS-GYARIAFID---GEMWQ--IQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRT-NRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQL-KASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1554
            P    LP +G L  I++    +    L K HG +  +  +GM+ V++ +     +       ++++GR K      MS GY  IA  D   G +W+  I    + K F    +G +++ E+A+ E     D+L +  G  VD  D   L  +NII  F++ K F +++ ++     L     K  D L +   +  + D   +L  + L+ + N K + +  DKL+   +  H++T + N    DL D FL  +  + +    ++ + TD ++  + +++ LAGLETT TSL W   ++     +Q +V   I ++IG  R P  +DR+ L Y +A++ E+ R+S   PL L H+++ D++I+GY +PK   V  NL+A H D + W +P +F P+RF++ D  G  +   + N   F  G+R C GESLAKME F+  T ++Q+F
Sbjct:    3 PGPTPLPLIGNLLSIKSSNIHFELANLAKTHGDIMMIELFGMKIVVVTSGPLAREVLMGKHINDFAGRPKRFTFEYMSKGYKDIALNDYSPGLVWKRKIVHSGLRKYFP--SLGDTIAKELAKLE-----DKLNSDVGVPVDSKDEFFLLVLNIICSFLSGKAFDKEDPEFSETLEL---VTKTVDTLSM---SASILDAFPFLIHFPLQASKNFKRIAELRDKLMGNILTFHKETFNEN-HIRDLTDAFLKAKLDIEREDKKAAGEVTDEEVALMMMDVYLAGLETTVTSLRWIIAYLMNNQEVQSRVQSRIDDVIGDRR-PLMSDRQGLPYMEALVAEVLRLSPPIPLGLPHKSILDTTIDGYTIPKGTTVLFNLWAIHHDPREWPEPDKFDPDRFINED--GKFEVPGDRNFLPFMAGRRVCLGESLAKMELFLIMTRLLQQF 431          

Query:  247 PTEKGLPFVGVLHQIETPIFRYYERLIKKHG-SVFAVRY-GMRDVIILNDYQTVKSAFVDDGSNYSGRWK--VSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNR-KVLFDAVDKLVQEEIDEHRKTLDLNSEGE--DLIDRFLIKQHQLKASTGSSKQF-TDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSD 1584
            P     PFVG   QI   + +    L K++G  VF V+  G R VII N     +     +G + + R    V  ++  +G + I       W++QR  V      +G G  +   +  QE   L D      G  VD    + L  +N+I   +  KR+   + ++  I    +   K       L Y       M WL  + L+   + K    A D+L+Q +I EHR+T     EGE  DL D  L      K    ++    T+  L     ++ +AG ETTTT+L W FL+++ Y  +Q ++H+E+ ++I   R P   DRK L Y +A + E+ R+S V PL +  +A    +I GY +P++  V+ NL+A H DE  W  P +F P RFL    N    Y+    +  FG G R C GESLAKME F+F + ++ RF++       D
Sbjct:   30 PGPPLYPFVGNFPQIGPVLHKSLTSLGKQYGRGVFQVQLLGKRFVIIDNIKLARQVLLKKNGRDVADRTSAYVIDAISRNGCSVIFGKYSPTWKLQRRVVHSALRMYGSGVRILEALILQEVDNLCDIFANSQGAPVDTKLPLTLSVMNVICALVFGKRYGLDDAEFTDIVATTESMAKLASPENPLIY-------MPWLRFFPLQVVKKMKETVTARDRLIQRKITEHRETY---KEGEIRDLTDALLKSLEDAKQEDNNAMSLLTEDHLLIAINDVFMAGFETTTTALRWIFLYVAAYPEVQARIHQELDDVISFGRDPLIADRKSLPYLEATILEVLRISPVFPL-IRRKARKQLNIGGYCIPEETFVYVNLWAIHHDEAEWVDPYKFRPSRFLE-GTNSASAYS----MLPFGAGVRVCVGESLAKMELFLFVSRLLHRFKLNLKGQCPD 467          

Query:  247 PTEKGLPFVGVLHQIETPIFRY-YERLIKKHGSVFAVR-YGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMS-GYARIAFID---GEMWQ--IQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRT-NRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQL-KASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1554
            P    LP +G L  I++    +    L K HG +  +  +GM+ V++ +     +       ++++GR K      MS GY  IA  D   G +W+  I    + K F    +G +++ E+A+ E     D+L +  G  VD  D   L  +NII  F+T K F +++ ++          +   D + +   +  + D   +L  + L+ + N K + +  DKL+   +  H++T + N    DL D FL  +  + +    ++++ TD ++  + +++ LAGLETT TSL W   ++     +Q +V   I ++IG  R P  +DR+ L Y +A++ E+ R+S   PL L H+++ D++I+GY +PK   V  NL+A H D + W +P +F P+RF++ D  G  +   + N   F  G+R C GESLAKME F+  T ++Q+F
Sbjct:    3 PGPTPLPLIGNLLSIKSSNIHFELANLAKTHGDIMMIELFGMKIVVVTSGPLAREVLMGKHINDFAGRPKRFTFEYMSKGYKDIALNDYSPGLVWKRKIVHSGLRKYFP--SLGDTIAKELAKLE-----DKLNSDVGVPVDSKDEFFLLVLNIICSFLTGKAFDKEDPEFSETLEFVTMTV---DTISM---SASILDAFPFLIHFPLQASKNFKRIAELRDKLMGNILTFHKETFNEN-HIRDLTDAFLKAKLDIEREDKKAAEEVTDEEVALMMMDVYLAGLETTVTSLRWIIAYLMNNQEVQSRVQSRIDDVIGDRR-PLMSDRQGLPYMEALVAEVLRLSPPIPLGLPHKSILDTTIDGYTIPKGTTVLFNLWAIHHDPREWPEPDKFDPDRFINED--GKFEVPGDRNFLPFMAGRRVCLGESLAKMELFLIMTRLLQQF 431          

Query:  247 PTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFV----------LKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFS-RKEDKYKTIGNL-----GQQALKQKDCLQLL-FYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQ---FTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEE 1599
            P    LP +G LH + +       RL   +G ++ +  G +  ++LN Y+  K A +  G+ ++GR       + S ++R     G  +Q   P +          +K F     G+++  EI   E  YL D   +   +  D    +     N++ +    +RF+   E+ ++ + +L     G  A    D   LL ++   L  ++         +T  K+  D ++K  +E  D  R    + ++ +DL    + + +Q  + T S       TD  +     + ++AG ET T  L W+  F  KY  +Q +  ++I  +I  ++  T  DRK L Y +A + E+ R+ S+ PLA+ H AM D  + GY++ K   V  NL+A   D KVW+ P EF PERFL  D  G     ++E    +GMG R C GE LA+ME F+F   +++ FE R SE + + L  E
Sbjct:    1 PGPLPLPLIGNLHLLSSKPHLDLARLGNIYGPIYTLNMGSQLAVVLNSYEIAKEALMKRGNAFAGR---PHHFVGSKFSRGG--KGVGFQNYTPTLRRQQKTIMKTVKYFETLKTGENLQ-EIITNEVDYLCDLFVSHGCQDFDPRRDMTFAAGNVVGRITFGERFTVENEEFWQLMDSLKIFVEGLTATSFIDAFPLLRYFPFSLVKRV---------QTAVKLRDDVLNKRFREHQDRLRGDGMVLAKSKDLTYALIEEANQKTSRTDSQSDTLILTDDHVMMTMNDTIMAGSETPTMLLLWNIYFFVKYPDVQARAFKQIDKVISPDQPITWEDRKRLPYLEAFIAEVMRIISIMPLAVPHLAMVDMVLAGYHISKGTTVIVNLWAMGHDPKVWDAPMEFRPERFL--DSRGGFSTASSEGFTPYGMGLRSCPGEQLARMELFLFTVRLLRMFEFRASEALPEMLDGE 454          

Query:  322 LIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALK-QKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEID--EHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSD 1584
            L K +G VF V +G++ V++L  Y+TVK A V++   +  R        M+    I F +GE W+  R F L    DFG+GK ++ E   +EC YLI  LE   G  VD++  ++  T NIIS  +   RF   + +++ + +   + ++     L  L+   P      W   WI    NRK++ + V+  V++  D  +H K     S     +D FLIK+ + + S      FT+  L      L  AG +TT T+L W  L M+KY  IQ KVHEE+  ++G  +    +DRK+L Y  AV+ EI RV+++ P+++ H+   D + +GY + K   V   L +   DE  WE P  F P  FLS     + K+   +    F  G+R C GESLAKME F+FFTS++QRF       VS+
Sbjct:   67 LSKSYGPVFTVYFGIQKVVVLAGYKTVKEALVNNAEEFGDRDITPMFQDMNKGHGILFANGESWKELRRFALTTLRDFGMGKRIAEEKILEECDYLIQGLEKHQGNPVDLTCPLNYATSNIISSIVYGSRFDYDDPRFRNLVSRANETIRINGHPLTHLYNMFP-----RWF-RWI---KNRKIILNNVEMTVKDVKDLVKHLKETLNPSVCRGFVDCFLIKKQKEEDSCVKESHFTEQNLVFSVSNLFAAGTDTTATTLRWGLLLMAKYPHIQDKVHEELAKVLGGRQV-RVDDRKNLPYADAVIHEIQRVANIIPMSIPHKTNRDVTFHGYLIQKGTTVIPLLASVLNDENEWESPHTFNPHHFLSK----EGKFVKRDAFMPFSAGRRACLGESLAKMELFLFFTSLLQRFHFTPPPGVSE 476          

Query:  247 PTEKGLPFVGVLHQIETPIFRY-YERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKV--LFDAVDKL---VQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVRGSK 1638
            P  + LPF+G LH+I   I    ++    K+G+VF++       ++LN  + +K A +  G ++  R ++     +     I   +G  W+ QR F L    +FG+GK    +  ++EC Y+        GK  D   L++    NII   +  +RF   + +Y+ I     + +K +     L Y +           W+++R    +  LF  VDK+   V+ +I+EH++ LD     +D ID FLI   +++ + G    F    L   +L+L  AG ETTTT+L W  LFM  Y  IQ++VH EI  +IG  R P+  D++++ YT AV+ EI R+  + P+ +   A  D+ ++ Y +PK  ++   L+    DE VWE P  F P+ FL    N D  +   E    FG GKR C GE LA+ME F+FFTS +QRF   FS    +   +  L G  G +R  K
Sbjct:   42 PGPRSLPFIGDLHRIRPTILHLQFKEFAAKYGNVFSLNIFGGKTVVLNGTKLLKEALIQKGDDFVDRPQIPLFSDLIENKGIVMTNGIQWKHQRRFALHTLRNFGLGKKTMEKYIQEECHYITQAFAEHQGKPFDAQPLLNSAVSNIICCLVFGERFEYSDKEYQQILQDLTEVVKLQGSFSALAYNV---------FPWLMKRFPGPLQKLFTLVDKIMDFVKIKIEEHKENLDPACP-KDYIDSFLI---EMEKNQGEDFGFDIKNLCACTLDLFGAGSETTTTTLYWGLLFMIHYPDIQEEVHAEIDAVIGSSRQPSMADKENMPYTDAVIHEIQRMGDIVPIGVARMASRDTMLDNYTIPKGTMIMPALHTVLHDESVWETPHSFNPQHFL----NQDGTFKKREAFFPFGAGKRVCLGEQLARMELFLFFTSFLQRFS--FSTAGGE---KPPLEGRMGTIRSPK 489          

Query:  247 PTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKY-KTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRR---TNRKV--LFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIG 1611
            P    LPF+G LH+I+   +   +    +K+G+VF++       +ILN Y+ VK A V  G ++  R  +   +       I   +G  W+ QR F L    +FG+GK       + EC Y+        GK  D   LI+    NII   +  +RF   + +Y K + NL    + +     +L+   P          W+++R    ++K+  L   +   V+ +I+EH+   D  S  ED ID FLI   +++ S      F    +   +++L LAG ETTTT+L W  L+M  Y  IQ+KVH EI  +IG  R P+  D++ + YT AV+ EI R+  + P  +  +A  D++++ Y +PK  ++   L++   DE +W+ P  F P+ FL    + D K+   E  N FG GKR C GE LA+ME F+FFTS+ QRF   FS    + L  E+ +G
Sbjct:   42 PGPHSLPFIGDLHRIQPARLHVQFTEFAEKYGNVFSLHLLGERTVILNGYKQVKEALVQQGDDFVDRPTIPLFVDTIDNKGIVMSNGNSWKQQRRFALHTLRNFGLGKKTMETYIQNECHYITQTFADKQGKPFDAQFLINNAVSNIICCLVFGERFEYSDQEYQKILRNLNDLLILEGSVSAMLYNMFP----------WLMKRLPGPHQKIFSLTRKIIDFVKIKINEHKGNFD-PSAPEDYIDSFLI---EMEKSQDKDSGFDIDNMCICTMDLFLAGTETTTTTLYWGLLYMIYYPDIQEKVHAEIDAVIGSSRQPSMADKESMPYTDAVIHEIQRMGDIVPQGVFRQANRDTTLDKYTIPKGTIIVPALHSVLHDESMWDNPHSFDPKNFL----DKDGKFCKREAFNPFGAGKRVCLGEQLARMELFLFFTSLFQRFS--FSAPTGEQLSLESRMG 483          

Query:  313 YERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALK-QKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDAL 1590
            + +L  ++G ++++R+G R  ++LN ++ +K A V  G +   R  +     ++    + F +G  W  QR F L     FG GK     +   E  +  +EL+   G+ +D   +I+    NII   +   RF+  + K+K +  L  +AL+ +      L+ +  L  +    C     +T + + +  V   + EE+ EH+K+ D  S+  D ID +L +  + K   GS+  F +  L    L+L +AG ETT+T+L W+FL+M+KY  IQ+KV  EI  +IGK R P   DR +L YT AV+ E+ R+ ++ PL+L H    D  + G+ +PK  L+  NL +  FDEK WE P  F P  FL    N D K+        F  GKR C GE+LA+ME F+FFTS MQ F       V   L
Sbjct:   89 FSKLAAEYGDLYSLRFGQRWTVVLNGHKALKEALVTKGDSVVDRPHLPLQDEIAKGLGVIFSNGANWTEQRRFALSTLRYFGFGKKSLEPVILNEFAHCAEELKRFKGEPLDPHLIINNTVSNIICHLVFGHRFNYGDKKFKKLMLLFDRALQIEASIWAQLYNSFTLIMR----CLPGPHKTLQHI-WREVQDFIGEELKEHKKSWD-PSDARDYIDFYLTEIQKTKGQEGST--FDEENLIMCVLDLFVAGSETTSTTLRWAFLYMAKYPEIQEKVQAEIHKVIGKSRPPCMEDRAELPYTDAVIHEVQRIGNIVPLSLPHATNKDVQLGGFTIPKGVLIIPNLTSVLFDEKEWETPHAFNPGHFL----NKDGKFVKRGAFIPFSAGKRLCLGENLARMELFLFFTSFMQHFSFSMPAGVEPVL 503          

Query:  322 LIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSD 1584
            L KK+G VF V +G + V++L  Y+TVK A V+    +  R         +    I F +GE W   R F L    DFG+GK +S +   +EC +LI+ELE L GK  D +  I     N++S  +  KRF  ++   + I +   + +     + +L Y +       WL  W+          +A    +++ I E + TLD ++     +D FL ++  LK   GS   + D  L    + L  AG +TT T++EW  LFM+KY  IQ++V EE+  ++G  +     DRK+L +T AV+ E  R++++AP+A+ H    D +  GY++ K   V   L +  +DE  WE P+ F P  FL  D  G  K+        F  G+R C GESLA+M+ F+FFTS++Q F       VS+
Sbjct:   67 LSKKYGPVFVVNFGPKKVVVLAGYRTVKQALVNQAKEFGNREVTPIFYDFNKEHGILFANGESWNEMRRFALSTLRDFGMGKRISEQNIIEECRWLIEELEKLQGKPFDNTHTISYAVSNVLSGLMFGKRFDYQDPLLQAIVDRDNEIIYLTGTVSILLYNM-----FPWLGPWLKNWKTLMKNMEAAKTDMKKIIAELKDTLDPDTR-RCFVDAFLTQKQNLKEVNGS--HYHDDNLLYTVMNLFAAGTDTTATTIEWCLLFMAKYPHIQERVQEELNWVVGSRQV-RIEDRKNLPFTDAVIHESQRLANIAPMAIPHTTSKDVTFQGYFIKKGTTVLPLLTSVLYDESEWESPRTFNPSHFL--DKEG--KFLKRGAFMPFSAGRRVCLGESLARMDIFLFFTSLLQHFSFTPPPGVSE 474          

Query:  163 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVRGSKIKNYIFTKLK 1668
            YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQLRRLSLELLLAGLETTTTSLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPT ND+KDL+YTQAV+DEIFRVSSV PLALVHRAMNDSSINGY+VPKD+LV+SNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKY AN++LN FG+GKRRC GESLA+ME F+FFTSIMQRFEVRF+EDVSDALYEEALIGNEGIVRGSKIKNYIFTKLK
Sbjct:    5 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQLRRLSLELLLAGLETTTTSLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTLNDKKDLHYTQAVIDEIFRVSSVGPLALVHRAMNDSSINGYHVPKDSLVYSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYKANDSLNPFGVGKRRCTGESLARMEIFVFFTSIMQRFEVRFAEDVSDALYEEALIGNEGIVRGSKIKNYIFTKLK 506          

Query:  163 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVRGSKIKNYIFTKLK*RNFIK 1686
            YLCTFLLGAAI+WKF R T IPK L+RIPTEKGLP +GVLH+IE+PI RYYERLIKKHGSVFAVR+GMRDVIILNDYQTVKSAFV DGSNYSGRWKVSQSL+MSG A IAFIDGEMWQ QR F+LKVFHDFG+GKSVSYEI RQEC +LIDELETL GK VDVSDLI LYTVNIISKFI NKRFSRKEDKYK + +L Q ALKQKD  Q LFYTLPLFDKM WLCDWILRRTNR++ FDAVDKLVQEE+DEHRKTLDLNSEGED IDRFLIKQHQLK STGSS+QFTDFQL RLS+ELL+AGLETT T+L WSFLFMSKYT IQ+KVH EI+  +GKERFPT NDRK L+YTQAVMDE+ RVSSVAPLA VHRAM DSS+NGYYVPKD+LVFSNLYAC+FDEKVW+KPKEFYPE FLSTDING I YT NE+LN FG+GKRRC GESLA+ME F+FFTSIMQRFEV+F+EDVS+ALYEEALIGNEG+VR SKIKN+IF KL+ ++  K
Sbjct:    5 YLCTFLLGAAIYWKFIRLTSIPKELKRIPTEKGLPIIGVLHKIESPILRYYERLIKKHGSVFAVRFGMRDVIILNDYQTVKSAFVHDGSNYSGRWKVSQSLMMSGNAGIAFIDGEMWQTQRTFMLKVFHDFGMGKSVSYEIVRQECHFLIDELETLIGKCVDVSDLIQLYTVNIISKFIMNKRFSRKEDKYKRLSDLSQHALKQKDFFQFLFYTLPLFDKMNWLCDWILRRTNRRIPFDAVDKLVQEELDEHRKTLDLNSEGEDFIDRFLIKQHQLKTSTGSSEQFTDFQLLRLSMELLVAGLETTMTTLGWSFLFMSKYTNIQKKVHNEIIKTVGKERFPTLNDRKYLHYTQAVMDEVIRVSSVAPLAFVHRAMEDSSLNGYYVPKDSLVFSNLYACNFDEKVWKKPKEFYPEHFLSTDINGVIIYTPNESLNPFGVGKRRCVGESLARMEIFVFFTSIMQRFEVKFAEDVSEALYEEALIGNEGVVRSSKIKNFIFEKLENQDLAK 512          

Query:  181 LGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVRGSKIKNYIFTK 1662
            LG  I+WK  +RT I KGL+ IPTEKGLPFVGVLHQ+ETPI +YYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRW++  SLL +  + IAFIDG+ WQ QR F+LKV HDFG+GKSVSYEI RQEC  L++ELETL GK VD SDLIHLYTVNIISKF  NKRFSR +DK + I +L     KQKD LQ  F+ LP+FDKM  LCDWI+ RT+R   FDAV K  QEE+DEHRK+LDLNSEGEDLIDRFLIKQHQLKASTGS + FTDFQL R+SLELL+AGLETTTT+LEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGN+G+VR SKI  +IFTK
Sbjct:   11 LGVTIYWKLIKRTSISKGLKIIPTEKGLPFVGVLHQMETPILKYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLVSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNDGLVRCSKINKFIFTK 504          

Query:  163 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVRGSKIKNYIFTKLK 1668
            +L   +   A+ + F R  PIPKGL+++P EKG P +G+L  +  PI  YYERLIKKHG VF ++ G+R + +LNDY+ +++A +D+  N+SGRW++ QSLL +  A I   DG+   I R F++KV H+FG+G   S    + EC  L++ LE   G+ + VSD+I  Y  NII+KF+ NK FS  + K   I N+  +  + KD  Q L++TLP+ D+   +CD+++  T RK LF+ V +++Q+EI+EHRKT D+ +EGEDLIDRFL+KQ QLK+S  S K FTDFQL R  LEL LAG ETT+T   WS  FMSKY  IQ KVH+EI++ IG ER PT NDRKDL YT AVMDEI R+SSV PLAL+HR  ND+ +N Y++PKD+LV  NLYACH D  VWEKP+EFYPE FLS   NG+IKY   + LN FGMGKR+C GESL +M+ FIFF SI+QRF+V F++ V+++ ++EAL  NEGIVR   I  ++F +++
Sbjct:    5 FLLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPLIGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYRAIRNALIDNKDNFSGRWRLFQSLLGTQNAGIVSTDGDQTHIHRRFIIKVMHEFGMGTLRSLTNIQTECTALLECLEKCQGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRVCDFLMSFTTRKDLFNKVHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVKSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQSKVHQEIIDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPSINEFVFNRIQ 506          

Query:  163 YLCTFLLGAAIF-WKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLL--MSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQXXXXXXXXXXXXXXXXXXXXEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNEGIVRGSKIKNYIFTK 1662
            Y  TF+L    F +   R+ PIPKGL+ IP E GLP +G +H+IE P+  Y  +L +K G +F ++ GMR +++LN+Y+ +K A +DD +N+SGRW  SQ  +  ++  + I F DG++W  QR F+LKV  DFG+GKS S EI + EC   +DEL+TL+G+ VD S+LI +YT NIIS+FI NKRF+R +   + I      + K KD +QL+    P FD  + +C  I   T++   F  +     EEI+EHR  LDL SEGEDL+DRFLIKQH+LK STG+ + F D+QL R S+EL +AG ETT+T+L W  LFMSKY  IQ+KVH+EI  IIGKER PT ND+K LNYTQAVMDE+ R+SSVAP+ L+HR  +D++ING+Y+PKD+L+F NLYACH D ++WE P  FYPE FLS D NG  KY   E L  F +GKR+C GESLA+ E FIFF S++QRF++ F+E++S+  Y + +IGNEG++R S IKN++F +
Sbjct:    5 YCVTFILIFLYFLYWVCRKPPIPKGLKEIPMESGLPIIGAIHKIEPPMHHYLLKLGRKLGPIFRIKLGMRKIVVLNNYEMIKKALIDDANNFSGRW--SQRFIKEITHDSGIIFKDGKIWATQRSFILKVLRDFGLGKSKSIEIVQNECFNFLDELDTLSGQIVDFSELIPIYTTNIISRFIMNKRFTRDDPNIQLIEETINNSTKNKDIIQLILLMFPCFDNSSLICQLIYLLTSKWKSFVKIQNYFGEEIEEHRTNLDLTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRTSVELFIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFAEEISEDKYSQTIIGNEGVIRTSDIKNFLFKR 505