HECT and RLD domain containing E3 ubiquitin protein ligase family member 1

Overview
NameHECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Smed IDSMED30004625
Length (bp)6414
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 (SMED30004625) t-SNE clustered cells

Violin plots show distribution of expression levels for HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 (SMED30004625) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 (SMED30004625) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 (SMED30004625) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30004625

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30004625h1SMcG0014262 dd_Smed_v4_9316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30004625h1SMcG0014262 dd_Smed_v4_9316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30004625h1SMcG0014262 dd_Smed_v4_9316_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Category 3 cellSMED30004625h1SMcG0014262 GAKN01015423.1SmedAsxl_pearson_GAKN01PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30004625h1SMcG0014262 GAKN01015423.1SmedAsxl_pearson_GAKN01PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parapharyngeal regionSMED30004625h1SMcG0014262 DN303757smed_ncbi_20240424PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30004625h1SMcG0014262 DN303757smed_ncbi_20240424PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymal cellSMED30004625h1SMcG0014262 DN303757smed_ncbi_20240424PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Human
Match: HERC1 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:HGNC Symbol;Acc:HGNC:4867])

HSP 1 Score: 84.3445 bits (207), Expect = 3.512e-15
Identity = 68/228 (29.82%), Postives = 108/228 (47.37%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVWGNPH--AFNSKDENCLFPVRLRQAI--MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEK-VQCMSRHKVFDISLSENHIVILGQ-NVIYSW 2086
            H LA T  G+++SWG G +GKLGHG+   +  P LI+  L+G  +  +S G  HS+AV+E G  + WG          D N      L + I  +  + CG   T  LS + R V+  G      +L   D    + P +IE L      +   I K+   S   L L + G +Y+ G G  LGC   +      K ++ ++  ++ D+S+ ++H + L   N +Y+W
Sbjct:  469 HTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGG-DNGKLGHGDTNRVYKPKVIEAL------QGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAW 689

HSP 2 Score: 73.9442 bits (180), Expect = 3.938e-12
Identity = 63/235 (26.81%), Postives = 110/235 (46.81%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFN---SKDENCLFPVR---LRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTE--CQIHKTFEKVQCMSRHKVFDISLSENHIVILGQN-VIYSWSLTAE 2101
            H +ALT+ G+++SWG G +GKLGHG+   +  P  IEAL+G  +  +SCG  HS+ V+  G  F +GN            N   P R   L    +  + CG + T  +S +   V+  G      +L   +   +  P  I+ L    C     I+K+A  +   + L  +G++Y+ G    +G  E   + H   +++  ++   + D+++   H + L  N  +Y+W   +E
Sbjct: 4093 HSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDG-DYGKLGLGNSTAKSSPQKIDVL----CGIG--IKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSE 4320

HSP 3 Score: 67.781 bits (164), Expect = 3.474e-10
Identity = 37/113 (32.74%), Postives = 65/113 (57.52%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW----GNPHAFNSKDENCLFPVRLRQAI----MSSIVCGPHSTFFLS 1735
            +H  A+T+ G+LY+WG G FG+LGHGD   ++ PTL++ +   N+  +SCG+SH+ A+S+ G   VW    G+       D N ++  ++ +A+    +  +  G  S+  L+
Sbjct:  521 RHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGSSHTIALSKDGRT-VWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALT 630

HSP 4 Score: 65.0846 bits (157), Expect = 2.091e-9
Identity = 31/70 (44.29%), Postives = 46/70 (65.71%), Query Frame = 2 
Query: 1418 SQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            S H +AL++ G+ ++S+GGG  GKLGHGD    + P +IEAL+G  IR +  G+  S A++ TG  + WG
Sbjct:  570 SSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWG 639

HSP 5 Score: 61.6178 bits (148), Expect = 2.303e-8
Identity = 31/71 (43.66%), Postives = 42/71 (59.15%), Query Frame = 2 
Query: 1379 IEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            IE +AVG      ++H LAL  +G +Y+WG  S G+LG G       PTL+  L+G N+R IS G  HS+A
Sbjct: 4293 IEDVAVG------AEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAA 4357

HSP 6 Score: 58.5362 bits (140), Expect = 2.126e-7
Identity = 26/68 (38.24%), Postives = 41/68 (60.29%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H   +T  G+L+++G G +G+LG G+  +K  P  + AL GY I  ++CG +H+ AVS  G   VW 
Sbjct: 4144 KHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADG-SMVWA 4210
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Human
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868])

HSP 1 Score: 73.559 bits (179), Expect = 4.966e-12
Identity = 32/68 (47.06%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H  ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct:  304 RHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWG 371

HSP 2 Score: 67.0106 bits (162), Expect = 5.150e-10
Identity = 28/68 (41.18%), Postives = 43/68 (63.24%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +++ G +HS+ V+  G  + WG
Sbjct: 1296 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWG 1363

HSP 3 Score: 63.929 bits (154), Expect = 4.075e-9
Identity = 27/70 (38.57%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV+++G  + WG+
Sbjct:  461 AQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGD 530

HSP 4 Score: 63.929 bits (154), Expect = 4.740e-9
Identity = 45/167 (26.95%), Postives = 76/167 (45.51%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
             +R++C K       +   +R+I C  +    L + G++ +  +       H +            N   +K K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F
Sbjct:  329 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGD------------NTTQLKPKMVKVLLGHRVIQVACGSRDAQ-TLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYF 482

HSP 5 Score: 62.3882 bits (150), Expect = 1.195e-8
Identity = 26/66 (39.39%), Postives = 40/66 (60.61%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW 1621
            H   +T  G LY+WG G +G+LGH D  D+  P L+EAL+G+ + +I+CG+  +  +  T    VW
Sbjct: 1349 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVW 1414

HSP 6 Score: 59.6918 bits (143), Expect = 8.547e-8
Identity = 29/72 (40.28%), Postives = 41/72 (56.94%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T  GQ+Y+WG    G+ G+G       PTL++ L G  I  ++CG+SHS A
Sbjct:  505 KIVHVAVG------ALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVA 570

HSP 7 Score: 55.4546 bits (132), Expect = 1.662e-6
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 1453 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSK 1567
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Human
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868])

HSP 1 Score: 73.559 bits (179), Expect = 5.461e-12
Identity = 32/68 (47.06%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H  ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 3057 RHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWG 3124

HSP 2 Score: 67.0106 bits (162), Expect = 5.602e-10
Identity = 28/68 (41.18%), Postives = 43/68 (63.24%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +++ G +HS+ V+  G  + WG
Sbjct: 4049 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWG 4116

HSP 3 Score: 66.2402 bits (160), Expect = 8.812e-10
Identity = 29/75 (38.67%), Postives = 46/75 (61.33%), Query Frame = 2 
Query: 1412 NDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR----GYNIRNISCGASHSSAVSETGLGFVWG 1624
            +D  H LAL   G++YSWG G  G+LGHGD +    P +I A      G ++ +I+CG+++S+A++  G  + WG
Sbjct:  502 SDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWG 576

HSP 4 Score: 65.855 bits (159), Expect = 1.329e-9
Identity = 42/149 (28.19%), Postives = 73/149 (48.99%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGA--SHSSAVSETGLGFVWGN---PHAFNSKDENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGL 1840
            S +  A+T  G+LY+WG G++G+LGHG   D+  P L+  L+G  + +++CG+  + + AV+E G  + WG+           + C  P    +L+   +  + CG  S F +++ K    Y   +     L         YP ++EGL
Sbjct:  560 STYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCG--SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGL 706

HSP 5 Score: 63.929 bits (154), Expect = 4.411e-9
Identity = 27/70 (38.57%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV+++G  + WG+
Sbjct: 3214 AQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGD 3283

HSP 6 Score: 63.929 bits (154), Expect = 5.130e-9
Identity = 45/167 (26.95%), Postives = 76/167 (45.51%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
             +R++C K       +   +R+I C  +    L + G++ +  +       H +            N   +K K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F
Sbjct: 3082 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGD------------NTTQLKPKMVKVLLGHRVIQVACGSRDAQ-TLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYF 3235

HSP 7 Score: 62.3882 bits (150), Expect = 1.291e-8
Identity = 26/66 (39.39%), Postives = 40/66 (60.61%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW 1621
            H   +T  G LY+WG G +G+LGH D  D+  P L+EAL+G+ + +I+CG+  +  +  T    VW
Sbjct: 4102 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVW 4167

HSP 8 Score: 61.2326 bits (147), Expect = 3.140e-8
Identity = 38/113 (33.63%), Postives = 57/113 (50.44%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNP---HAFN----SKDENCLFPVRLRQAIMSSIVCGPHSTFFLS 1735
            SQ  +ALT+ GQ+YSWG G   +LGHG       P L+E L+G  + +++ G++H  A++E      WG+      F+    +K E    P  L    +  I CGP  +F  S
Sbjct:  666 SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALP-GLDTKHIVGIACGPAQSFAWS 777

HSP 9 Score: 59.6918 bits (143), Expect = 9.189e-8
Identity = 29/72 (40.28%), Postives = 41/72 (56.94%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T  GQ+Y+WG    G+ G+G       PTL++ L G  I  ++CG+SHS A
Sbjct: 3258 KIVHVAVG------ALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVA 3323

HSP 10 Score: 55.4546 bits (132), Expect = 1.775e-6
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 4206 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSK 4320
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Human
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868])

HSP 1 Score: 70.8626 bits (172), Expect = 2.981e-11
Identity = 32/69 (46.38%), Postives = 47/69 (68.12%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
             +H  ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct:  293 GRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWG 361

HSP 2 Score: 65.4698 bits (158), Expect = 1.278e-9
Identity = 38/121 (31.40%), Postives = 61/121 (50.41%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN---PHAFNSKDENCLFPVRLRQAIMS----SIVCGPHSTFFLSINKRNVYY 1759
             +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +++ G +HS+ V+  G  + WG        +S  E+ L P +L +A+       I CG      L +   +  +
Sbjct: 1285 GKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKP-KLVEALQGHRVVDIACGSGDAQTLCLTDDDTVW 1404

HSP 3 Score: 63.929 bits (154), Expect = 4.086e-9
Identity = 37/123 (30.08%), Postives = 59/123 (47.97%), Query Frame = 2 
Query: 1328 LFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPVRLR 1681
            L H   SP + P V   +  + V   +     H   +T  G LY+WG G +G+LGH D  D+  P L+EAL+G+ + +I+CG+  +  +  T    VW        K      + C  P+++R
Sbjct: 1308 LGHGNRSPCDRPRVIESLRGIEV-VDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKVR 1429

HSP 4 Score: 62.003 bits (149), Expect = 1.711e-8
Identity = 27/70 (38.57%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV+++G  + WG+
Sbjct:  451 AQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGD 520

HSP 5 Score: 62.003 bits (149), Expect = 1.785e-8
Identity = 45/168 (26.79%), Postives = 76/168 (45.24%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFN 1642
             +R++C K       +   +R+I C  +    L + G++ +  +       H +            N   +K K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F 
Sbjct:  319 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGD------------NTTQLKPKMVKVLLGHRVIQVACGSRDAQ-TLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFR 473

HSP 6 Score: 57.3806 bits (137), Expect = 3.734e-7
Identity = 29/72 (40.28%), Postives = 41/72 (56.94%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T  GQ+Y+WG    G+ G+G       PTL++ L G  I  ++CG+SHS A
Sbjct:  495 KIVHVAVG------ALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVA 560
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Human
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868])

HSP 1 Score: 68.9366 bits (167), Expect = 1.166e-10
Identity = 43/153 (28.10%), Postives = 73/153 (47.71%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSS--AVSETGLGFVWGN---PHAFNSKDENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTK 1852
            S +  A+T  G+LY+WG G++G+LGHG   D+  P L+  L+G  + +++CG+  +   AV+E G  + WG+           + C  P    +L+   +  + CG  S F +++ K    Y   +     L         YP ++EGL   K
Sbjct:  560 STYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCG--SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKK 710

HSP 2 Score: 68.1662 bits (165), Expect = 1.722e-10
Identity = 70/313 (22.36%), Postives = 129/313 (41.21%), Query Frame = 2 
Query: 1205 NHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR----GYNIRNISCGASHSSAVSETGLGFVWGN------PHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGIN--LGCTECQIHKTFEKV------QCMSRHKVFDISLSENHIVILGQNV-IYSW 2086
            N  V +I C+E   ++L+  G++ +++ +       + +     Q  +  N   +              +D  H LAL   G++YSWG G  G+LGHGD +    P +I A      G ++ +I+CG+++S+A++  G  + WG        H  +  +   +    L+   +  + CG      L++ +    +        +L          P +IE L      +   + K+   S   + L  +G +YS G G N  LG      H T E V      + +   KV D++    H + L ++  ++SW
Sbjct:  450 NLGVTQIACAEKRFLILSRNGRVYTQAYN------SDTLAPQLVQGLASRNIVKIAAH-----------SDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKL------QDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLG------HGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSW 733

HSP 3 Score: 59.6918 bits (143), Expect = 7.868e-8
Identity = 37/113 (32.74%), Postives = 56/113 (49.56%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFN-------SKDENCLFPVRLRQAIMSSIVCGPHSTFFLS 1735
            SQ  +ALT+ GQ+YSWG G   +LGHG       P L+E L+G  + +++ G++H  A++E      WG+            +K E    P    + I+  I CGP  +F  S
Sbjct:  666 SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALPGLDTKHIV-GIACGPAQSFAWS 777
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Celegans
Match: K11D2.1 (pep chromosome:WBcel235:I:12504117:12505010:1 gene:WBGene00010768.1 transcript:K11D2.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K11D2.1)

HSP 1 Score: 51.6026 bits (122), Expect = 1.984e-6
Identity = 33/117 (28.21%), Postives = 56/117 (47.86%), Query Frame = 2 
Query: 1448 GQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG-NPHAFNSKDENC--LFPV-------RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGS 1768
            G L+S G G+ G+LG G +     P  IE L G  I+ ++CG  H+ A++E G  + WG N +    KD+    ++PV       +  +  +  + C  H+T  +       + LG+
Sbjct:  100 GNLFSMGTGTRGELGVGLIRRVDEPVHIEQLVGIRIKKVACGGWHTVALTEGGDAYTWGWNRYGQLGKDKGSTEVYPVLIDPEEEKFGEENILDVACTEHNTQIVIKTGHAPFVLGT 216
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Celegans
Match: K11D2.1 (pep chromosome:WBcel235:I:12497467:12505010:1 gene:WBGene00010768.1 transcript:K11D2.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K11D2.1)

HSP 1 Score: 51.9878 bits (123), Expect = 2.271e-6
Identity = 33/117 (28.21%), Postives = 56/117 (47.86%), Query Frame = 2 
Query: 1448 GQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG-NPHAFNSKDENC--LFPV-------RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGS 1768
            G L+S G G+ G+LG G +     P  IE L G  I+ ++CG  H+ A++E G  + WG N +    KD+    ++PV       +  +  +  + C  H+T  +       + LG+
Sbjct:  150 GNLFSMGTGTRGELGVGLIRRVDEPVHIEQLVGIRIKKVACGGWHTVALTEGGDAYTWGWNRYGQLGKDKGSTEVYPVLIDPEEEKFGEENILDVACTEHNTQIVIKTGHAPFVLGT 266
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Fly
Match: HERC2 (gene:FBgn0031107 transcript:FBtr0301344)

HSP 1 Score: 80.1073 bits (196), Expect = 2.870e-14
Identity = 34/68 (50.00%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LALT  G+++SWG G  GKLGHG+      P L+EALR   IR+++CG+SHS+A+S  G  + WG
Sbjct: 3083 KHALALTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWG 3150

HSP 2 Score: 76.2554 bits (186), Expect = 3.771e-13
Identity = 30/68 (44.12%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LALT  G++Y+WG G  GKLGHG+ +    P L+E L G ++ +I+CG++HS+A++ +G    WG
Sbjct: 4146 KHCLALTTEGEVYAWGEGEDGKLGHGNRMSYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVLTWG 4213

HSP 3 Score: 62.7734 bits (151), Expect = 5.277e-9
Identity = 38/122 (31.15%), Postives = 57/122 (46.72%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPVRLRQAIMSSIV---CGPHSTFFLSINKRNVYY 1759
            S H  A+T  G + +WG G +G+LGHGD  D+  P L+EAL GY   +I+CG+  +  +  T    VW        K      + C  P ++       +V   CG  S F +++ K    Y
Sbjct: 4197 SAHSAAITASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGGSDGCKLPYKIESLAGLGVVKVECG--SQFSVALTKSGAVY 4316

HSP 4 Score: 62.3882 bits (150), Expect = 6.787e-9
Identity = 34/87 (39.08%), Postives = 51/87 (58.62%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILN---DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            KIE LA G  ++     SQ  +ALT+ G +Y+WG G F +LGHG +     P  + AL+G  I +I+ G+ H  A S++G  + WG+
Sbjct: 4287 KIESLA-GLGVVKVECGSQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGEVYTWGD 4372

HSP 5 Score: 62.003 bits (149), Expect = 7.762e-9
Identity = 37/146 (25.34%), Postives = 70/146 (47.95%), Query Frame = 2 
Query: 1187 LSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            LSC      ++++ C E ++++L+  G++ +  ++ P  +              P+   +V   +     G     + +H LA+  +   YSWG G   +LGHGD   +  PT I AL  + ++++ CG S+S+A++  G    WG
Sbjct:  568 LSC---RFQIKQVACCETQMLILSQEGKLYTWRLAKPEAE--------------PLPMEEVAHDVFISIAGH---CEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHARAVPTKIAALEQHCVQSVYCGCSYSAAITCGGNLLTWG 693

HSP 6 Score: 62.003 bits (149), Expect = 8.094e-9
Identity = 34/83 (40.96%), Postives = 46/83 (55.42%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            ++ Q+A G     D+Q  LALT+ G ++SWG G FGKLG G      +P  IE L G  +  I CGA  S A++  G  + WG
Sbjct: 3178 RVVQVACG---SRDAQ-TLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTWG 3256

HSP 7 Score: 58.151 bits (139), Expect = 1.137e-7
Identity = 26/70 (37.14%), Postives = 42/70 (60.00%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G++++WG G + +LGHG       P  I  LRG  + +++ GA H  AV++ G  + WG+
Sbjct: 3240 AQFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRGRRVIHVAVGALHCLAVTDAGQVYAWGD 3309

HSP 8 Score: 54.6842 bits (130), Expect = 1.531e-6
Identity = 30/83 (36.14%), Postives = 41/83 (49.40%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPV 1672
            H LA+T  GQ+Y+WG    G+ G G+      P L+  L    +  ++CG+SHS A         WG P+A  S DE    PV
Sbjct: 3294 HCLAVTDAGQVYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVFVNRVACGSSHSIA---------WGLPNA--SSDEEKRGPV 3365

HSP 9 Score: 54.299 bits (129), Expect = 1.810e-6
Identity = 24/68 (35.29%), Postives = 41/68 (60.29%), Query Frame = 2 
Query: 1406 ILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGL 1609
            I   S H +A +  G++Y+WG    G+LG G +     P L+ AL+G +I  ++CG++H+ A+S + L
Sbjct: 4351 IATGSLHCVACSDSGEVYTWGDNDEGQLGDGTVTAIQRPRLVAALQGKHIVKVTCGSAHTLALSTSQL 4418

HSP 10 Score: 52.7582 bits (125), Expect = 5.711e-6
Identity = 25/70 (35.71%), Postives = 39/70 (55.71%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            D+Q  L +T    ++SWG G +GKLG G       P  IE+L G  +  + CG+  S A++++G  + WG
Sbjct: 4251 DAQ-TLCITDDDNVWSWGDGDYGKLGRGGSDGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWG 4319
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Fly
Match: Herc4 (gene:FBgn0035207 transcript:FBtr0072670)

HSP 1 Score: 60.4622 bits (145), Expect = 1.929e-8
Identity = 56/231 (24.24%), Postives = 105/231 (45.45%), Query Frame = 2 
Query: 1211 SVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVK-CKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHG-DMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN----PHAFNSKDE--NCLFPVRLRQAI---MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIE-----GLPFTKC 1855
            +V+++ C     + L   G++ +   +  S   H+           P+  P+++   I Q+  G      S+H LAL+  GQ+ SWG    G+LGH  D      P ++  L    +  I+CG +HS A++  G  + WG+        NS ++  +C +P+RL   +   +++I CG + +F +S +     +  + C   +L   D   + YP+ ++     G+ F  C
Sbjct:   41 AVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHDLPTK------RPLLIPELQDYVIIQICCG------SRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCG--QLGLNDETNRSYPTQLKTLRTLGVRFVAC 257

HSP 2 Score: 53.5286 bits (127), Expect = 2.337e-6
Identity = 48/224 (21.43%), Postives = 90/224 (40.18%), Query Frame = 2 
Query: 1211 SVREIICSENEIIVLNNLGQIRS--------RSISPPSTKKHENIVMLFHQCWSPINFPDV-KCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN------PHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEG 1837
            +V +I C  N  + L + G++ S          ++ P+   H         C  P+    +    +  +A G        H   +++ G ++ WG  + G+LG  D  ++  PT ++ LR   +R ++CG   S  ++  G  F  G        H F+S +      + L  + ++ + CG   T  L  ++  VY  G   S  +L T+       P ++ G
Sbjct:  144 TVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTH---------CNYPLRLTTLLGIPLAAIACG------GNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRGRVYAFGLG-SSGQLGTRSTKSLMLPQVVIG 351
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Fly
Match: Herc4 (gene:FBgn0035207 transcript:FBtr0072671)

HSP 1 Score: 60.4622 bits (145), Expect = 1.929e-8
Identity = 56/231 (24.24%), Postives = 105/231 (45.45%), Query Frame = 2 
Query: 1211 SVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVK-CKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHG-DMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN----PHAFNSKDE--NCLFPVRLRQAI---MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIE-----GLPFTKC 1855
            +V+++ C     + L   G++ +   +  S   H+           P+  P+++   I Q+  G      S+H LAL+  GQ+ SWG    G+LGH  D      P ++  L    +  I+CG +HS A++  G  + WG+        NS ++  +C +P+RL   +   +++I CG + +F +S +     +  + C   +L   D   + YP+ ++     G+ F  C
Sbjct:   41 AVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHDLPTK------RPLLIPELQDYVIIQICCG------SRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCG--QLGLNDETNRSYPTQLKTLRTLGVRFVAC 257

HSP 2 Score: 53.5286 bits (127), Expect = 2.337e-6
Identity = 48/224 (21.43%), Postives = 90/224 (40.18%), Query Frame = 2 
Query: 1211 SVREIICSENEIIVLNNLGQIRS--------RSISPPSTKKHENIVMLFHQCWSPINFPDV-KCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN------PHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEG 1837
            +V +I C  N  + L + G++ S          ++ P+   H         C  P+    +    +  +A G        H   +++ G ++ WG  + G+LG  D  ++  PT ++ LR   +R ++CG   S  ++  G  F  G        H F+S +      + L  + ++ + CG   T  L  ++  VY  G   S  +L T+       P ++ G
Sbjct:  144 TVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTH---------CNYPLRLTTLLGIPLAAIACG------GNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRGRVYAFGLG-SSGQLGTRSTKSLMLPQVVIG 351
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Fly
Match: Herc4 (gene:FBgn0035207 transcript:FBtr0310555)

HSP 1 Score: 59.6918 bits (143), Expect = 3.795e-8
Identity = 45/161 (27.95%), Postives = 79/161 (49.07%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHG-DMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN----PHAFNSKDE--NCLFPVRLRQAI---MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIE-----GLPFTKC 1855
            S+H LAL+  GQ+ SWG    G+LGH  D      P ++  L    +  I+CG +HS A++  G  + WG+        NS ++  +C +P+RL   +   +++I CG + +F +S +     +  + C   +L   D   + YP+ ++     G+ F  C
Sbjct:  104 SRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNC--GQLGLNDETNRSYPTQLKTLRTLGVRFVAC 262

HSP 2 Score: 53.5286 bits (127), Expect = 2.359e-6
Identity = 48/224 (21.43%), Postives = 90/224 (40.18%), Query Frame = 2 
Query: 1211 SVREIICSENEIIVLNNLGQIRS--------RSISPPSTKKHENIVMLFHQCWSPINFPDV-KCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN------PHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEG 1837
            +V +I C  N  + L + G++ S          ++ P+   H         C  P+    +    +  +A G        H   +++ G ++ WG  + G+LG  D  ++  PT ++ LR   +R ++CG   S  ++  G  F  G        H F+S +      + L  + ++ + CG   T  L  ++  VY  G   S  +L T+       P ++ G
Sbjct:  149 TVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTH---------CNYPLRLTTLLGIPLAAIACG------GNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRGRVYAFGLG-SSGQLGTRSTKSLMLPQVVIG 356
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Fly
Match: CG6678 (gene:FBgn0038917 transcript:FBtr0084148)

HSP 1 Score: 55.8398 bits (133), Expect = 2.382e-7
Identity = 33/104 (31.73%), Postives = 54/104 (51.92%), Query Frame = 2 
Query: 1313 ENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            EN V     C     F + + +++QL  G       +H + L  +G +++WG G  G+LG  ++  + +P L+EAL G  I  I+ G  HS+A+S  G  + WG
Sbjct:  156 ENCVYSIPSCLH--QFSERQFRVKQLQCG------HEHAVLLNANGDVFTWGNGLRGQLGLAELRVEETPQLLEALAGIKITQIAAGGWHSAAISAFGDLYTWG 251
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Zebrafish
Match: herc1 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:ZFIN;Acc:ZDB-GENE-030131-8542])

HSP 1 Score: 86.2705 bits (212), Expect = 5.787e-16
Identity = 70/228 (30.70%), Postives = 108/228 (47.37%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVWGNPH--AFNSKDENCLFPVRLRQAI--MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEK-VQCMSRHKVFDISLSENHIVILGQ-NVIYSW 2086
            H LA T  G+++SWG G +GKLGHG+   +  P LI+  L+G  +  +S G  HS+AVSE G  + WG          D N      L + I  +  + CG   T  LS + R V+  G      +L   D    + P ++E L      +   I K+   S   L L + G +Y+ G G  LGC   +      K ++ ++  +V DIS+ ++H + L   N +Y+W
Sbjct:  464 HTLAFTSEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGG-DNGKLGHGDTNRVYKPKVVEAL------QGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELATTRVVDISIGDSHCLALSHDNEVYAW 684

HSP 2 Score: 72.0182 bits (175), Expect = 9.916e-12
Identity = 41/120 (34.17%), Postives = 61/120 (50.83%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFN---SKDENCLFPVR---LRQAIMSSIVCGPHSTFFLSINKRNVYYLG 1765
            H +ALT+ G+++SWG G +GKLGHG+   +  P  IEAL+G  +  +SCG  HS+ V+  G  F +GN            N   P R   L    +  + CG + T  +S +   V+  G
Sbjct: 4084 HSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKLPERVSALEGHQVGQVACGLNHTLAVSADGMTVWAFG 4203

HSP 3 Score: 66.6254 bits (161), Expect = 4.862e-10
Identity = 36/113 (31.86%), Postives = 65/113 (57.52%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW----GNPHAFNSKDENCLFPVRLRQAI----MSSIVCGPHSTFFLS 1735
            +H  A+++ G+LY+WG G FG+LGHGD   ++ PTL++ +   N+  +SCG+SH+ A+S+ G   VW    G+       D N ++  ++ +A+    +  +  G  S+  L+
Sbjct:  516 RHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGSSHTIALSKDGRT-VWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFIRKVCAGSQSSLALT 625

HSP 4 Score: 64.3142 bits (155), Expect = 2.041e-9
Identity = 30/70 (42.86%), Postives = 46/70 (65.71%), Query Frame = 2 
Query: 1418 SQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            S H +AL++ G+ ++S+GGG  GKLGHGD    + P ++EAL+G  IR +  G+  S A++ TG  + WG
Sbjct:  565 SSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFIRKVCAGSQSSLALTSTGQVYAWG 634

HSP 5 Score: 60.8474 bits (146), Expect = 2.570e-8
Identity = 32/71 (45.07%), Postives = 42/71 (59.15%), Query Frame = 2 
Query: 1379 IEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            IE +AVG      ++H L L+  G +Y+WG  S G+LG G       PTLI AL+G NI+ IS G  HS+A
Sbjct: 4284 IEDVAVG------AEHTLTLSSTGDVYAWGSNSEGQLGLGHTNHVREPTLISALQGKNIQQISAGRCHSAA 4348

HSP 6 Score: 57.3806 bits (137), Expect = 2.736e-7
Identity = 25/68 (36.76%), Postives = 42/68 (61.76%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H   +T  G+L+S+G G +G+LG G+  +K  P  + AL G+ +  ++CG +H+ AVS  G+  VW 
Sbjct: 4135 KHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKLPERVSALEGHQVGQVACGLNHTLAVSADGMT-VWA 4201
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Zebrafish
Match: herc1 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:ZFIN;Acc:ZDB-GENE-030131-8542])

HSP 1 Score: 86.2705 bits (212), Expect = 5.787e-16
Identity = 70/228 (30.70%), Postives = 108/228 (47.37%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVWGNPH--AFNSKDENCLFPVRLRQAI--MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEK-VQCMSRHKVFDISLSENHIVILGQ-NVIYSW 2086
            H LA T  G+++SWG G +GKLGHG+   +  P LI+  L+G  +  +S G  HS+AVSE G  + WG          D N      L + I  +  + CG   T  LS + R V+  G      +L   D    + P ++E L      +   I K+   S   L L + G +Y+ G G  LGC   +      K ++ ++  +V DIS+ ++H + L   N +Y+W
Sbjct:  464 HTLAFTSEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGG-DNGKLGHGDTNRVYKPKVVEAL------QGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELATTRVVDISIGDSHCLALSHDNEVYAW 684

HSP 2 Score: 72.0182 bits (175), Expect = 9.916e-12
Identity = 41/120 (34.17%), Postives = 61/120 (50.83%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFN---SKDENCLFPVR---LRQAIMSSIVCGPHSTFFLSINKRNVYYLG 1765
            H +ALT+ G+++SWG G +GKLGHG+   +  P  IEAL+G  +  +SCG  HS+ V+  G  F +GN            N   P R   L    +  + CG + T  +S +   V+  G
Sbjct: 4084 HSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKLPERVSALEGHQVGQVACGLNHTLAVSADGMTVWAFG 4203

HSP 3 Score: 66.6254 bits (161), Expect = 4.862e-10
Identity = 36/113 (31.86%), Postives = 65/113 (57.52%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW----GNPHAFNSKDENCLFPVRLRQAI----MSSIVCGPHSTFFLS 1735
            +H  A+++ G+LY+WG G FG+LGHGD   ++ PTL++ +   N+  +SCG+SH+ A+S+ G   VW    G+       D N ++  ++ +A+    +  +  G  S+  L+
Sbjct:  516 RHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGSSHTIALSKDGRT-VWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFIRKVCAGSQSSLALT 625

HSP 4 Score: 64.3142 bits (155), Expect = 2.041e-9
Identity = 30/70 (42.86%), Postives = 46/70 (65.71%), Query Frame = 2 
Query: 1418 SQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            S H +AL++ G+ ++S+GGG  GKLGHGD    + P ++EAL+G  IR +  G+  S A++ TG  + WG
Sbjct:  565 SSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFIRKVCAGSQSSLALTSTGQVYAWG 634

HSP 5 Score: 60.8474 bits (146), Expect = 2.570e-8
Identity = 32/71 (45.07%), Postives = 42/71 (59.15%), Query Frame = 2 
Query: 1379 IEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            IE +AVG      ++H L L+  G +Y+WG  S G+LG G       PTLI AL+G NI+ IS G  HS+A
Sbjct: 4284 IEDVAVG------AEHTLTLSSTGDVYAWGSNSEGQLGLGHTNHVREPTLISALQGKNIQQISAGRCHSAA 4348

HSP 6 Score: 57.3806 bits (137), Expect = 2.736e-7
Identity = 25/68 (36.76%), Postives = 42/68 (61.76%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H   +T  G+L+S+G G +G+LG G+  +K  P  + AL G+ +  ++CG +H+ AVS  G+  VW 
Sbjct: 4135 KHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKLPERVSALEGHQVGQVACGLNHTLAVSADGMT-VWA 4201
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Zebrafish
Match: herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:ZFIN;Acc:ZDB-GENE-070718-6])

HSP 1 Score: 75.0998 bits (183), Expect = 1.291e-12
Identity = 32/68 (47.06%), Postives = 48/68 (70.59%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H +ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 3051 RHAMALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYSWG 3118

HSP 2 Score: 71.2478 bits (173), Expect = 1.814e-11
Identity = 47/149 (31.54%), Postives = 73/149 (48.99%), Query Frame = 2 
Query: 1205 NHSVREIICSENEIIVLNNLGQI-----RSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGY----NIRNISCGASHSSAVSETGLGFVWG 1624
            N  V +I+CSE   ++L   G +     +S +++P          ML H   S         KI +LA       D QH LAL+ +G+++SWG G  G+LGHGD      PT+I    G      + +I+CG+++S+A++  G    WG
Sbjct:  440 NLGVTQIVCSEKGFLILTITGAVYTQNYKSTTLAP----------MLVHALTSR--------KIMKLAAH----PDGQHYLALSVNGEVFSWGCGDGGRLGHGDTTYLEEPTMISVFSGRPVGKQVVHIACGSTYSAAITADGELHTWG 566

HSP 3 Score: 69.3218 bits (168), Expect = 6.941e-11
Identity = 29/68 (42.65%), Postives = 44/68 (64.71%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G+LYSWG    GKLGHG+      P +IE+LRG  + +I+ G +HS+ ++ +G  + WG
Sbjct: 4045 KHCLALSSEGELYSWGEAEDGKLGHGNRSPCDRPRVIESLRGVEVVDIAAGGAHSACITASGELYTWG 4112

HSP 4 Score: 68.1662 bits (165), Expect = 1.477e-10
Identity = 30/70 (42.86%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV+ETG  F WG+
Sbjct: 3208 AQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQMVEGLRGKKIVHVAVGALHCLAVTETGQVFAWGD 3277

HSP 5 Score: 66.6254 bits (161), Expect = 4.860e-10
Identity = 26/66 (39.39%), Postives = 42/66 (63.64%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW 1621
            H   +T  G+LY+WG G +G+LGHGD  D+  P L+EAL+G+ + +++CG+  +  +  T    VW
Sbjct: 4098 HSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGHRVIDVACGSGDAQTLCLTDDDMVW 4163

HSP 6 Score: 65.0846 bits (157), Expect = 1.213e-9
Identity = 27/72 (37.50%), Postives = 49/72 (68.06%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGA--SHSSAVSETGLGFVWGN 1627
            S +  A+T  G+L++WG G++G+LGHG   D+ +P L+ AL+G  + +++CG+  + + AV+E G  + WG+
Sbjct:  550 STYSAAITADGELHTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLAVTENGQVWSWGD 621

HSP 7 Score: 63.5438 bits (153), Expect = 4.093e-9
Identity = 44/167 (26.35%), Postives = 76/167 (45.51%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
             +R++C K       +   +R+I C  +    + + G++ S  +       H +            N   ++ K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F
Sbjct: 3076 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGD------------NTTQLRPKLVKVLLGHRVVQVACGSRDAQ-TLALTDEGMVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYF 3229

HSP 8 Score: 62.7734 bits (151), Expect = 7.119e-9
Identity = 36/110 (32.73%), Postives = 58/110 (52.73%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHA-------FNSKDENCLFPVRLRQAIMSSIVCGPHSTF 1726
            SQ  +ALT+ GQ+Y+WG G   +LGHG       P L+++L+G  + +I+ G++H  A++E G    WG+          F++K +    P  L    +  I CGP  +F
Sbjct:  656 SQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSLQGKRVVDIAVGSTHCLALTEEGEVHSWGSNDKLQHFDTLFSNKKQPKALP-GLNSKHIVGISCGPGQSF 764

HSP 9 Score: 58.5362 bits (140), Expect = 1.134e-7
Identity = 28/72 (38.89%), Postives = 42/72 (58.33%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T+ GQ+++WG    G+ G+G       PTL++ L G  I  ++CG+SHS A
Sbjct: 3252 KIVHVAVG------ALHCLAVTETGQVFAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVA 3317

HSP 10 Score: 55.4546 bits (132), Expect = 9.955e-7
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 4202 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSK 4316

HSP 11 Score: 52.7582 bits (125), Expect = 6.462e-6
Identity = 25/70 (35.71%), Postives = 39/70 (55.71%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            D+Q  L LT    ++SWG G +GKLG G       P  I++L G  +  + CG+  S A++++G  + WG
Sbjct: 4150 DAQ-TLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWG 4218
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Zebrafish
Match: si:ch211-281g13.4 (si:ch211-281g13.4 [Source:ZFIN;Acc:ZDB-GENE-090311-16])

HSP 1 Score: 72.0182 bits (175), Expect = 8.317e-12
Identity = 61/238 (25.63%), Postives = 102/238 (42.86%), Query Frame = 2 
Query: 1202 ENHSVREIICSENEIIVLNNLGQI---RSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCL-------FPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCS-ENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKI 1882
            +N  V +I C +   + L+N GQ+      +      +K + ++       S    P     + Q++ G        H   L+  G ++ WG  S G+LG GD  D+  PT++++L G    +ISCG  H++ +S+ G  F +G+   F     N L           L  + +S + CG H T  L      +Y  G  C  + +L   + + Q  P  +  LP T C+    +EKI
Sbjct:  116 DNTKVIQIACGDQHSVALSNDGQLFVWGENAHGQLGLRKEQALIQSPQHLQSLCGIP-----VAQISAG------GNHSFVLSLSGVVFGWGSNSAGQLGLGDTTDRFVPTIVKSLSGKKTVSISCGGEHTATLSKGGTVFTFGS-GGFGQLGHNSLKDEHHPRLVAELWGSKVSQVTCGRHHTLVLVALTNRIYSFG--CGMQGQLGNGEQVKQSVPLPVL-LP-TDCNCEFTMEKI 337
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Zebrafish
Match: herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:ZFIN;Acc:ZDB-GENE-070718-6])

HSP 1 Score: 71.633 bits (174), Expect = 1.071e-11
Identity = 78/319 (24.45%), Postives = 131/319 (41.07%), Query Frame = 2 
Query: 1205 NHSVREIICSENEIIVLNNLGQI-----RSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGY----NIRNISCGASHSSAVSETGLGFVWGN------PHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGIN--LGCTECQIHKTFEKVQ------CMSRHKVFDISLSENHIVILG-QNVIYSWS 2089
            N  V +I+CSE   ++L   G +     +S +++P          ML H   S         KI +LA       D QH LAL+ +G+++SWG G  G+LGHGD      PT+I    G      + +I+CG+++S+A++  G    WG        H  +      +    L+   +  + CG      L++ +    +        +L          P ++E L      +   I K+   S   + L  +G +Y+ G G N  LG      H T E V+       +   +V DI++   H + L  +  ++SW 
Sbjct:  440 NLGVTQIVCSEKGFLILTITGAVYTQNYKSTTLAP----------MLVHALTSR--------KIMKLAA----HPDGQHYLALSVNGEVFSWGCGDGGRLGHGDTTYLEEPTMISVFSGRPVGKQVVHIACGSTYSAAITADGELHTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLVEKL------QDLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLG------HGTDEHVRYPKLLDSLQGKRVVDIAVGSTHCLALTEEGEVHSWG 724

HSP 2 Score: 60.077 bits (144), Expect = 3.211e-8
Identity = 37/113 (32.74%), Postives = 59/113 (52.21%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHA-------FNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLS 1735
            SQ  +ALT+ GQ+Y+WG G   +LGHG       P L+++L+G  + +I+ G++H  A++E G    WG+          F++K +    P  L    +  I CGP  +F  S
Sbjct:  656 SQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSLQGKRVVDIAVGSTHCLALTEEGEVHSWGSNDKLQHFDTLFSNKKQPKALP-GLNSKHIVGISCGPGQSFSWS 767
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Xenopus
Match: HERC1 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:NCBI gene;Acc:100493988])

HSP 1 Score: 83.1889 bits (204), Expect = 5.871e-15
Identity = 69/230 (30.00%), Postives = 109/230 (47.39%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVWGNPH--AFNSKDENCLFPVRLRQAI--MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLP--FTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEK-VQCMSRHKVFDISLSENHIVILGQ-NVIYSW 2086
            H LA T  G+++SWG G +GKLGHG+   +  P LI+  L+G  +  +S G  HS+AV+E G  + WG          D N      L + I  +  + CG   T  LS + R V+  G      +L   D    + P ++E L   FT+        K+   S   L L + G +Y+ G G  LGC   +      K ++ ++  ++ DIS+ ++H + L   N +Y+W
Sbjct:  469 HTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGTLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGG-DNGKLGHGDTNRVYKPKVVEALQGMFTR--------KVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLALSHDNEVYAW 689

HSP 2 Score: 72.0182 bits (175), Expect = 1.366e-11
Identity = 31/68 (45.59%), Postives = 45/68 (66.18%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            H +ALT+ G+++SWG G +GKLGHG+   +  P  IEAL+G  +  +SCG  HS+ V+  G  F +GN
Sbjct: 4052 HSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTADGKLFTFGN 4119

HSP 3 Score: 67.781 bits (164), Expect = 2.729e-10
Identity = 40/113 (35.40%), Postives = 64/113 (56.64%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW----GNPHAFNSKDENCLFP---VRLRQAIMSSIVC-GPHSTFFLS 1735
            +H  A+T+ G+LY+WG G FG+LGHGD   ++ PTL++ +   N+  +SCG+SH+ A+S+ G   VW    G+       D N ++    V   Q + +  VC G  S+  L+
Sbjct:  521 RHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGSSHTIALSKDGRT-VWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFTRKVCAGSQSSLALT 630

HSP 4 Score: 63.1586 bits (152), Expect = 6.448e-9
Identity = 32/71 (45.07%), Postives = 44/71 (61.97%), Query Frame = 2 
Query: 1379 IEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            I+ +AVG      ++H LAL+  G++Y+WG  S G+LG G       PTL+ AL+G NIR IS G  HS+A
Sbjct: 4252 IDDIAVG------AEHTLALSASGEVYAWGSNSEGQLGLGHTNHVREPTLVTALQGKNIRQISAGRCHSAA 4316

HSP 5 Score: 62.3882 bits (150), Expect = 1.160e-8
Identity = 29/70 (41.43%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            S H +AL++ G+ ++S+GGG  GKLGHGD    + P ++EAL+G   R +  G+  S A++ TG  + WG
Sbjct:  570 SSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFTRKVCAGSQSSLALTSTGQVYAWG 639

HSP 6 Score: 55.4546 bits (132), Expect = 1.663e-6
Identity = 25/68 (36.76%), Postives = 41/68 (60.29%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H   +T  G+L+++G G +G+LG G+  +K  P  + AL G +I  ++CG +H+ AVS  G   VW 
Sbjct: 4103 KHSAVVTADGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGLHIGQVACGLNHTLAVSADG-SLVWA 4169
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Xenopus
Match: HERC1 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:NCBI gene;Acc:100493988])

HSP 1 Score: 83.1889 bits (204), Expect = 5.872e-15
Identity = 69/230 (30.00%), Postives = 109/230 (47.39%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVWGNPH--AFNSKDENCLFPVRLRQAI--MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLP--FTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEK-VQCMSRHKVFDISLSENHIVILGQ-NVIYSW 2086
            H LA T  G+++SWG G +GKLGHG+   +  P LI+  L+G  +  +S G  HS+AV+E G  + WG          D N      L + I  +  + CG   T  LS + R V+  G      +L   D    + P ++E L   FT+        K+   S   L L + G +Y+ G G  LGC   +      K ++ ++  ++ DIS+ ++H + L   N +Y+W
Sbjct:  469 HTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGTLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGG-DNGKLGHGDTNRVYKPKVVEALQGMFTR--------KVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLALSHDNEVYAW 689

HSP 2 Score: 72.0182 bits (175), Expect = 1.366e-11
Identity = 31/68 (45.59%), Postives = 45/68 (66.18%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            H +ALT+ G+++SWG G +GKLGHG+   +  P  IEAL+G  +  +SCG  HS+ V+  G  F +GN
Sbjct: 4065 HSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTADGKLFTFGN 4132

HSP 3 Score: 67.781 bits (164), Expect = 2.730e-10
Identity = 40/113 (35.40%), Postives = 64/113 (56.64%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW----GNPHAFNSKDENCLFP---VRLRQAIMSSIVC-GPHSTFFLS 1735
            +H  A+T+ G+LY+WG G FG+LGHGD   ++ PTL++ +   N+  +SCG+SH+ A+S+ G   VW    G+       D N ++    V   Q + +  VC G  S+  L+
Sbjct:  521 RHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGSSHTIALSKDGRT-VWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFTRKVCAGSQSSLALT 630

HSP 4 Score: 63.1586 bits (152), Expect = 6.449e-9
Identity = 32/71 (45.07%), Postives = 44/71 (61.97%), Query Frame = 2 
Query: 1379 IEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            I+ +AVG      ++H LAL+  G++Y+WG  S G+LG G       PTL+ AL+G NIR IS G  HS+A
Sbjct: 4265 IDDIAVG------AEHTLALSASGEVYAWGSNSEGQLGLGHTNHVREPTLVTALQGKNIRQISAGRCHSAA 4329

HSP 5 Score: 62.3882 bits (150), Expect = 1.160e-8
Identity = 29/70 (41.43%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            S H +AL++ G+ ++S+GGG  GKLGHGD    + P ++EAL+G   R +  G+  S A++ TG  + WG
Sbjct:  570 SSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFTRKVCAGSQSSLALTSTGQVYAWG 639

HSP 6 Score: 55.4546 bits (132), Expect = 1.664e-6
Identity = 25/68 (36.76%), Postives = 41/68 (60.29%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H   +T  G+L+++G G +G+LG G+  +K  P  + AL G +I  ++CG +H+ AVS  G   VW 
Sbjct: 4116 KHSAVVTADGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGLHIGQVACGLNHTLAVSADG-SLVWA 4182
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Xenopus
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:NCBI gene;Acc:100487407])

HSP 1 Score: 74.3294 bits (181), Expect = 2.962e-12
Identity = 32/68 (47.06%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H  ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 2943 RHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWG 3010

HSP 2 Score: 68.5514 bits (166), Expect = 1.900e-10
Identity = 37/120 (30.83%), Postives = 61/120 (50.83%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPVRLRQAI---MSSIVCGPHSTFFLSINKRNVYY 1759
            H   +T  G+LY+WG G +G+LGHGD  D+  P L+EAL+GY + +I+CG+  +  +  T    VW        K      + C  P+++       ++ + CG  S F +++ K    Y
Sbjct: 3977 HSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECG--SQFSVALTKSGAVY 4094

HSP 3 Score: 67.3958 bits (163), Expect = 4.111e-10
Identity = 28/68 (41.18%), Postives = 43/68 (63.24%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +I+ G +HS+ ++  G  + WG
Sbjct: 3924 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWG 3991

HSP 4 Score: 66.2402 bits (160), Expect = 9.432e-10
Identity = 44/149 (29.53%), Postives = 69/149 (46.31%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGL 1840
            S +  A+T  G+LY+WG G++G+LGHG   D+  P L+  L+G  + ++SCG+  +  +S T  G VW        K      + C  P    +L+   +  + CG  S F ++I K    Y   +     L         YP I+ GL
Sbjct:  536 STYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCG--SQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGL 682

HSP 5 Score: 63.1586 bits (152), Expect = 7.680e-9
Identity = 27/70 (38.57%), Postives = 44/70 (62.86%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV++ G  + WG+
Sbjct: 3100 AQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGD 3169

HSP 6 Score: 62.3882 bits (150), Expect = 1.260e-8
Identity = 44/167 (26.35%), Postives = 76/167 (45.51%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
             +R++C K       +   +R+I C  +    + + G++ +  +       H +            N   +K K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F
Sbjct: 2968 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGD------------NTTQLKPKMVKVLLGHRVIQVACGSRDAQ-TLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYF 3121

HSP 7 Score: 60.4622 bits (145), Expect = 5.244e-8
Identity = 36/118 (30.51%), Postives = 60/118 (50.85%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLF-PVRLRQAIMS-----------SIVCGPHSTFFLS 1735
            SQ  +A+T+ GQ+YSWG G   +LGHG       P ++  L+G  + +++ G++H  A++E+G  + WG      S D+   F  +R+ + + S            I CGP  +F  S
Sbjct:  642 SQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWG------SNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWS 753

HSP 8 Score: 58.5362 bits (140), Expect = 1.845e-7
Identity = 29/72 (40.28%), Postives = 40/72 (55.56%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T  GQ+Y+WG    G+ G+G       PTL+  L G  I  ++CG+SHS A
Sbjct: 3144 KIVHVAVG------ALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVA 3209

HSP 9 Score: 55.4546 bits (132), Expect = 1.417e-6
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 4081 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSK 4195

HSP 10 Score: 53.1434 bits (126), Expect = 6.915e-6
Identity = 25/70 (35.71%), Postives = 39/70 (55.71%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            D+Q  L LT    ++SWG G +GKLG G       P  I++L G  +  + CG+  S A++++G  + WG
Sbjct: 4029 DAQ-TLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWG 4097
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Xenopus
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:NCBI gene;Acc:100487407])

HSP 1 Score: 74.3294 bits (181), Expect = 2.963e-12
Identity = 32/68 (47.06%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H  ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 2952 RHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWG 3019

HSP 2 Score: 68.5514 bits (166), Expect = 1.900e-10
Identity = 37/120 (30.83%), Postives = 61/120 (50.83%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPVRLRQAI---MSSIVCGPHSTFFLSINKRNVYY 1759
            H   +T  G+LY+WG G +G+LGHGD  D+  P L+EAL+GY + +I+CG+  +  +  T    VW        K      + C  P+++       ++ + CG  S F +++ K    Y
Sbjct: 3999 HSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECG--SQFSVALTKSGAVY 4116

HSP 3 Score: 67.3958 bits (163), Expect = 4.112e-10
Identity = 28/68 (41.18%), Postives = 43/68 (63.24%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +I+ G +HS+ ++  G  + WG
Sbjct: 3946 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWG 4013

HSP 4 Score: 66.2402 bits (160), Expect = 9.434e-10
Identity = 44/149 (29.53%), Postives = 69/149 (46.31%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGL 1840
            S +  A+T  G+LY+WG G++G+LGHG   D+  P L+  L+G  + ++SCG+  +  +S T  G VW        K      + C  P    +L+   +  + CG  S F ++I K    Y   +     L         YP I+ GL
Sbjct:  455 STYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCG--SQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGL 601

HSP 5 Score: 63.1586 bits (152), Expect = 7.682e-9
Identity = 27/70 (38.57%), Postives = 44/70 (62.86%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV++ G  + WG+
Sbjct: 3109 AQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGD 3178

HSP 6 Score: 62.3882 bits (150), Expect = 1.260e-8
Identity = 44/167 (26.35%), Postives = 76/167 (45.51%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
             +R++C K       +   +R+I C  +    + + G++ +  +       H +            N   +K K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F
Sbjct: 2977 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGD------------NTTQLKPKMVKVLLGHRVIQVACGSRDAQ-TLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYF 3130

HSP 7 Score: 60.4622 bits (145), Expect = 5.245e-8
Identity = 36/118 (30.51%), Postives = 60/118 (50.85%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLF-PVRLRQAIMS-----------SIVCGPHSTFFLS 1735
            SQ  +A+T+ GQ+YSWG G   +LGHG       P ++  L+G  + +++ G++H  A++E+G  + WG      S D+   F  +R+ + + S            I CGP  +F  S
Sbjct:  561 SQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWG------SNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWS 672

HSP 8 Score: 58.5362 bits (140), Expect = 1.846e-7
Identity = 29/72 (40.28%), Postives = 40/72 (55.56%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T  GQ+Y+WG    G+ G+G       PTL+  L G  I  ++CG+SHS A
Sbjct: 3153 KIVHVAVG------ALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVA 3218

HSP 9 Score: 55.4546 bits (132), Expect = 1.417e-6
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 4103 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSK 4217

HSP 10 Score: 53.1434 bits (126), Expect = 6.916e-6
Identity = 25/70 (35.71%), Postives = 39/70 (55.71%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            D+Q  L LT    ++SWG G +GKLG G       P  I++L G  +  + CG+  S A++++G  + WG
Sbjct: 4051 DAQ-TLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWG 4119
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Xenopus
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:NCBI gene;Acc:100487407])

HSP 1 Score: 74.3294 bits (181), Expect = 2.966e-12
Identity = 32/68 (47.06%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H  ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 3030 RHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWG 3097

HSP 2 Score: 68.5514 bits (166), Expect = 1.902e-10
Identity = 37/120 (30.83%), Postives = 61/120 (50.83%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPVRLRQAI---MSSIVCGPHSTFFLSINKRNVYY 1759
            H   +T  G+LY+WG G +G+LGHGD  D+  P L+EAL+GY + +I+CG+  +  +  T    VW        K      + C  P+++       ++ + CG  S F +++ K    Y
Sbjct: 4077 HSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECG--SQFSVALTKSGAVY 4194

HSP 3 Score: 67.3958 bits (163), Expect = 4.116e-10
Identity = 28/68 (41.18%), Postives = 43/68 (63.24%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +I+ G +HS+ ++  G  + WG
Sbjct: 4024 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWG 4091

HSP 4 Score: 66.2402 bits (160), Expect = 9.444e-10
Identity = 44/149 (29.53%), Postives = 69/149 (46.31%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGL 1840
            S +  A+T  G+LY+WG G++G+LGHG   D+  P L+  L+G  + ++SCG+  +  +S T  G VW        K      + C  P    +L+   +  + CG  S F ++I K    Y   +     L         YP I+ GL
Sbjct:  536 STYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCG--SQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGL 682

HSP 5 Score: 63.1586 bits (152), Expect = 7.690e-9
Identity = 27/70 (38.57%), Postives = 44/70 (62.86%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV++ G  + WG+
Sbjct: 3187 AQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGD 3256

HSP 6 Score: 62.3882 bits (150), Expect = 1.261e-8
Identity = 44/167 (26.35%), Postives = 76/167 (45.51%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
             +R++C K       +   +R+I C  +    + + G++ +  +       H +            N   +K K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F
Sbjct: 3055 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGD------------NTTQLKPKMVKVLLGHRVIQVACGSRDAQ-TLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYF 3208

HSP 7 Score: 60.4622 bits (145), Expect = 5.250e-8
Identity = 36/118 (30.51%), Postives = 60/118 (50.85%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLF-PVRLRQAIMS-----------SIVCGPHSTFFLS 1735
            SQ  +A+T+ GQ+YSWG G   +LGHG       P ++  L+G  + +++ G++H  A++E+G  + WG      S D+   F  +R+ + + S            I CGP  +F  S
Sbjct:  642 SQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWG------SNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWS 753

HSP 8 Score: 58.5362 bits (140), Expect = 1.847e-7
Identity = 29/72 (40.28%), Postives = 40/72 (55.56%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T  GQ+Y+WG    G+ G+G       PTL+  L G  I  ++CG+SHS A
Sbjct: 3231 KIVHVAVG------ALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVA 3296

HSP 9 Score: 55.4546 bits (132), Expect = 1.418e-6
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 4181 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSK 4295

HSP 10 Score: 53.1434 bits (126), Expect = 6.922e-6
Identity = 25/70 (35.71%), Postives = 39/70 (55.71%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            D+Q  L LT    ++SWG G +GKLG G       P  I++L G  +  + CG+  S A++++G  + WG
Sbjct: 4129 DAQ-TLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWG 4197
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Mouse
Match: Herc1 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:MGI Symbol;Acc:MGI:2384589])

HSP 1 Score: 84.3445 bits (207), Expect = 2.126e-15
Identity = 69/228 (30.26%), Postives = 108/228 (47.37%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVWGNPH--AFNSKDENCLFPVRLRQAI--MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEK-VQCMSRHKVFDISLSENHIVILGQ-NVIYSW 2086
            H LA T  G+++SWG G +GKLGHG+   +  P LI+  L+G  +  +S G  HS+AV+E G  + WG          D N      L + I  +  + CG   T  LS + R V+  G      +L   D    + P +IE L      +   I K+   S   L L + G +Y+ G G  LGC   +      K ++ ++  ++ DIS+ ++H + L   N +Y+W
Sbjct:  469 HTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGG-DNGKLGHGDTNRVYKPKVIEAL------QGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLSLSHDNEVYAW 689

HSP 2 Score: 72.4034 bits (176), Expect = 8.391e-12
Identity = 31/68 (45.59%), Postives = 45/68 (66.18%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            H +ALT+ G+++SWG G +GKLGHG+   +  P  IEAL+G  +  +SCG  HS+ V+  G  F +GN
Sbjct: 4091 HSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGN 4158

HSP 3 Score: 67.781 bits (164), Expect = 2.385e-10
Identity = 37/113 (32.74%), Postives = 65/113 (57.52%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW----GNPHAFNSKDENCLFPVRLRQAI----MSSIVCGPHSTFFLS 1735
            +H  A+T+ G+LY+WG G FG+LGHGD   ++ PTL++ +   N+  +SCG+SH+ A+S+ G   VW    G+       D N ++  ++ +A+    +  +  G  S+  L+
Sbjct:  521 RHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGSSHTIALSKDGRT-VWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALT 630

HSP 4 Score: 65.0846 bits (157), Expect = 1.436e-9
Identity = 31/70 (44.29%), Postives = 46/70 (65.71%), Query Frame = 2 
Query: 1418 SQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            S H +AL++ G+ ++S+GGG  GKLGHGD    + P +IEAL+G  IR +  G+  S A++ TG  + WG
Sbjct:  570 SSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWG 639

HSP 5 Score: 61.2326 bits (147), Expect = 2.230e-8
Identity = 32/71 (45.07%), Postives = 41/71 (57.75%), Query Frame = 2 
Query: 1379 IEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            IE +AVG      ++H LAL   G +Y+WG  S G+LG G       PTL+  L+G NIR IS G  HS+A
Sbjct: 4291 IEDVAVG------AEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNIRQISAGRCHSAA 4355

HSP 6 Score: 58.5362 bits (140), Expect = 1.460e-7
Identity = 26/68 (38.24%), Postives = 41/68 (60.29%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H   +T  G+L+++G G +G+LG G+  +K  P  + AL GY I  ++CG +H+ AVS  G   VW 
Sbjct: 4142 KHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADG-SMVWA 4208
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Mouse
Match: Herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:MGI Symbol;Acc:MGI:103234])

HSP 1 Score: 73.559 bits (179), Expect = 3.747e-12
Identity = 32/68 (47.06%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H  ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 3058 RHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWG 3125

HSP 2 Score: 67.0106 bits (162), Expect = 3.844e-10
Identity = 28/68 (41.18%), Postives = 43/68 (63.24%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +++ G +HS+ V+  G  + WG
Sbjct: 4015 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWG 4082

HSP 3 Score: 66.2402 bits (160), Expect = 6.047e-10
Identity = 29/75 (38.67%), Postives = 46/75 (61.33%), Query Frame = 2 
Query: 1412 NDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR----GYNIRNISCGASHSSAVSETGLGFVWG 1624
            +D  H LAL   G++YSWG G  G+LGHGD +    P +I A      G ++ +I+CG+++S+A++  G  + WG
Sbjct:  503 SDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWG 577

HSP 4 Score: 65.4698 bits (158), Expect = 1.125e-9
Identity = 42/149 (28.19%), Postives = 73/149 (48.99%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGA--SHSSAVSETGLGFVWGN---PHAFNSKDENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGL 1840
            S +  A+T  G+LY+WG G++G+LGHG   D+  P L+  L+G  + +++CG+  + + AV+E G  + WG+           + C  P    +L+   +  + CG  S F +++ K    Y   +     L         YP ++EGL
Sbjct:  561 STYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCG--SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGL 707

HSP 5 Score: 63.929 bits (154), Expect = 3.027e-9
Identity = 27/70 (38.57%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV+++G  + WG+
Sbjct: 3215 AQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGD 3284

HSP 6 Score: 63.929 bits (154), Expect = 3.520e-9
Identity = 45/167 (26.95%), Postives = 76/167 (45.51%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
             +R++C K       +   +R+I C  +    L + G++ +  +       H +            N   +K K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F
Sbjct: 3083 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGD------------NTTQLKPKMVKVLLGHRVIQVACGSRDAQ-TLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYF 3236

HSP 7 Score: 62.3882 bits (150), Expect = 1.022e-8
Identity = 26/66 (39.39%), Postives = 40/66 (60.61%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW 1621
            H   +T  G LY+WG G +G+LGH D  D+  P L+EAL+G+ + +I+CG+  +  +  T    VW
Sbjct: 4068 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVW 4133

HSP 8 Score: 61.2326 bits (147), Expect = 2.084e-8
Identity = 38/113 (33.63%), Postives = 57/113 (50.44%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNP---HAFN----SKDENCLFPVRLRQAIMSSIVCGPHSTFFLS 1735
            SQ  +ALT+ GQ+YSWG G   +LGHG       P L+E L+G  + +++ G++H  A++E      WG+      F+    +K E    P  L    +  I CGP  +F  S
Sbjct:  667 SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALP-GLDSKHIVGIACGPAQSFAWS 778

HSP 9 Score: 59.6918 bits (143), Expect = 6.306e-8
Identity = 29/72 (40.28%), Postives = 41/72 (56.94%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T  GQ+Y+WG    G+ G+G       PTL++ L G  I  ++CG+SHS A
Sbjct: 3259 KIVHVAVG------ALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVA 3324

HSP 10 Score: 55.4546 bits (132), Expect = 1.218e-6
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 4172 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSK 4286

HSP 11 Score: 52.7582 bits (125), Expect = 7.518e-6
Identity = 25/70 (35.71%), Postives = 39/70 (55.71%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            D+Q  L LT    ++SWG G +GKLG G       P  I++L G  +  + CG+  S A++++G  + WG
Sbjct: 4120 DAQ-TLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWG 4188
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Mouse
Match: Herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:MGI Symbol;Acc:MGI:103234])

HSP 1 Score: 73.559 bits (179), Expect = 3.749e-12
Identity = 32/68 (47.06%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H  ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 3058 RHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWG 3125

HSP 2 Score: 67.0106 bits (162), Expect = 3.846e-10
Identity = 28/68 (41.18%), Postives = 43/68 (63.24%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +++ G +HS+ V+  G  + WG
Sbjct: 4051 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWG 4118

HSP 3 Score: 66.2402 bits (160), Expect = 6.050e-10
Identity = 29/75 (38.67%), Postives = 46/75 (61.33%), Query Frame = 2 
Query: 1412 NDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR----GYNIRNISCGASHSSAVSETGLGFVWG 1624
            +D  H LAL   G++YSWG G  G+LGHGD +    P +I A      G ++ +I+CG+++S+A++  G  + WG
Sbjct:  503 SDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWG 577

HSP 4 Score: 65.4698 bits (158), Expect = 1.125e-9
Identity = 42/149 (28.19%), Postives = 73/149 (48.99%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGA--SHSSAVSETGLGFVWGN---PHAFNSKDENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGL 1840
            S +  A+T  G+LY+WG G++G+LGHG   D+  P L+  L+G  + +++CG+  + + AV+E G  + WG+           + C  P    +L+   +  + CG  S F +++ K    Y   +     L         YP ++EGL
Sbjct:  561 STYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCG--SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGL 707

HSP 5 Score: 63.929 bits (154), Expect = 3.028e-9
Identity = 27/70 (38.57%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV+++G  + WG+
Sbjct: 3215 AQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGD 3284

HSP 6 Score: 63.929 bits (154), Expect = 3.522e-9
Identity = 45/167 (26.95%), Postives = 76/167 (45.51%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
             +R++C K       +   +R+I C  +    L + G++ +  +       H +            N   +K K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F
Sbjct: 3083 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGD------------NTTQLKPKMVKVLLGHRVIQVACGSRDAQ-TLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYF 3236

HSP 7 Score: 62.3882 bits (150), Expect = 1.022e-8
Identity = 26/66 (39.39%), Postives = 40/66 (60.61%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW 1621
            H   +T  G LY+WG G +G+LGH D  D+  P L+EAL+G+ + +I+CG+  +  +  T    VW
Sbjct: 4104 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVW 4169

HSP 8 Score: 61.2326 bits (147), Expect = 2.085e-8
Identity = 38/113 (33.63%), Postives = 57/113 (50.44%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNP---HAFN----SKDENCLFPVRLRQAIMSSIVCGPHSTFFLS 1735
            SQ  +ALT+ GQ+YSWG G   +LGHG       P L+E L+G  + +++ G++H  A++E      WG+      F+    +K E    P  L    +  I CGP  +F  S
Sbjct:  667 SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALP-GLDSKHIVGIACGPAQSFAWS 778

HSP 9 Score: 59.6918 bits (143), Expect = 6.308e-8
Identity = 29/72 (40.28%), Postives = 41/72 (56.94%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T  GQ+Y+WG    G+ G+G       PTL++ L G  I  ++CG+SHS A
Sbjct: 3259 KIVHVAVG------ALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVA 3324

HSP 10 Score: 55.4546 bits (132), Expect = 1.218e-6
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 4208 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSK 4322

HSP 11 Score: 52.7582 bits (125), Expect = 7.520e-6
Identity = 25/70 (35.71%), Postives = 39/70 (55.71%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            D+Q  L LT    ++SWG G +GKLG G       P  I++L G  +  + CG+  S A++++G  + WG
Sbjct: 4156 DAQ-TLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWG 4224
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Mouse
Match: Herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:MGI Symbol;Acc:MGI:103234])

HSP 1 Score: 73.559 bits (179), Expect = 3.749e-12
Identity = 32/68 (47.06%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H  ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 3058 RHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWG 3125

HSP 2 Score: 67.0106 bits (162), Expect = 3.846e-10
Identity = 28/68 (41.18%), Postives = 43/68 (63.24%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +++ G +HS+ V+  G  + WG
Sbjct: 4051 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWG 4118

HSP 3 Score: 66.2402 bits (160), Expect = 6.050e-10
Identity = 29/75 (38.67%), Postives = 46/75 (61.33%), Query Frame = 2 
Query: 1412 NDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR----GYNIRNISCGASHSSAVSETGLGFVWG 1624
            +D  H LAL   G++YSWG G  G+LGHGD +    P +I A      G ++ +I+CG+++S+A++  G  + WG
Sbjct:  503 SDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWG 577

HSP 4 Score: 65.4698 bits (158), Expect = 1.125e-9
Identity = 42/149 (28.19%), Postives = 73/149 (48.99%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGA--SHSSAVSETGLGFVWGN---PHAFNSKDENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGL 1840
            S +  A+T  G+LY+WG G++G+LGHG   D+  P L+  L+G  + +++CG+  + + AV+E G  + WG+           + C  P    +L+   +  + CG  S F +++ K    Y   +     L         YP ++EGL
Sbjct:  561 STYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCG--SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGL 707

HSP 5 Score: 63.929 bits (154), Expect = 3.028e-9
Identity = 27/70 (38.57%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV+++G  + WG+
Sbjct: 3215 AQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGD 3284

HSP 6 Score: 63.929 bits (154), Expect = 3.522e-9
Identity = 45/167 (26.95%), Postives = 76/167 (45.51%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
             +R++C K       +   +R+I C  +    L + G++ +  +       H +            N   +K K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F
Sbjct: 3083 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGD------------NTTQLKPKMVKVLLGHRVIQVACGSRDAQ-TLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYF 3236

HSP 7 Score: 62.3882 bits (150), Expect = 1.022e-8
Identity = 26/66 (39.39%), Postives = 40/66 (60.61%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW 1621
            H   +T  G LY+WG G +G+LGH D  D+  P L+EAL+G+ + +I+CG+  +  +  T    VW
Sbjct: 4104 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVW 4169

HSP 8 Score: 61.2326 bits (147), Expect = 2.085e-8
Identity = 38/113 (33.63%), Postives = 57/113 (50.44%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNP---HAFN----SKDENCLFPVRLRQAIMSSIVCGPHSTFFLS 1735
            SQ  +ALT+ GQ+YSWG G   +LGHG       P L+E L+G  + +++ G++H  A++E      WG+      F+    +K E    P  L    +  I CGP  +F  S
Sbjct:  667 SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALP-GLDSKHIVGIACGPAQSFAWS 778

HSP 9 Score: 59.6918 bits (143), Expect = 6.308e-8
Identity = 29/72 (40.28%), Postives = 41/72 (56.94%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T  GQ+Y+WG    G+ G+G       PTL++ L G  I  ++CG+SHS A
Sbjct: 3259 KIVHVAVG------ALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVA 3324

HSP 10 Score: 55.4546 bits (132), Expect = 1.218e-6
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 4208 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSK 4322

HSP 11 Score: 52.7582 bits (125), Expect = 7.520e-6
Identity = 25/70 (35.71%), Postives = 39/70 (55.71%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            D+Q  L LT    ++SWG G +GKLG G       P  I++L G  +  + CG+  S A++++G  + WG
Sbjct: 4156 DAQ-TLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWG 4224
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Mouse
Match: Herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:MGI Symbol;Acc:MGI:103234])

HSP 1 Score: 68.9366 bits (167), Expect = 7.193e-11
Identity = 69/292 (23.63%), Postives = 122/292 (41.78%), Query Frame = 2 
Query: 1412 NDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEAL----RGYNIRNISCGASHSSAVSETGLGFVWGN------PHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGIN--LGCTECQIHKTFEKV------QCMSRHKVFDISLSENHIVILGQNV-IYSWSLTAETFSF----IEEPFDYSITAISSTSLIN--HNKLINIAWSRNSE 2212
            +D  H LAL   G++YSWG G  G+LGHGD +    P +I A      G ++ +I+CG+++S+A++  G  + WG        H  +  +   +    L+   +  + CG      L++ +    +        +L          P +IE L      +   + K+   S   + L  +G +YS G G N  LG      H T E V      + +   KV D++    H + L ++  ++SW    +   F    + +P   ++  + S  ++        + AWS  SE
Sbjct:  503 SDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKL------QDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLG------HGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSSCSE 782
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. UniProt/SwissProt
Match: sp|Q15751|HERC1_HUMAN (Probable E3 ubiquitin-protein ligase HERC1 OS=Homo sapiens OX=9606 GN=HERC1 PE=1 SV=2)

HSP 1 Score: 84.3445 bits (207), Expect = 1.687e-14
Identity = 68/228 (29.82%), Postives = 108/228 (47.37%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVWGNPH--AFNSKDENCLFPVRLRQAI--MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEK-VQCMSRHKVFDISLSENHIVILGQ-NVIYSW 2086
            H LA T  G+++SWG G +GKLGHG+   +  P LI+  L+G  +  +S G  HS+AV+E G  + WG          D N      L + I  +  + CG   T  LS + R V+  G      +L   D    + P +IE L      +   I K+   S   L L + G +Y+ G G  LGC   +      K ++ ++  ++ D+S+ ++H + L   N +Y+W
Sbjct:  469 HTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGG-DNGKLGHGDTNRVYKPKVIEAL------QGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAW 689

HSP 2 Score: 73.9442 bits (180), Expect = 1.891e-11
Identity = 63/235 (26.81%), Postives = 110/235 (46.81%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFN---SKDENCLFPVR---LRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTE--CQIHKTFEKVQCMSRHKVFDISLSENHIVILGQN-VIYSWSLTAE 2101
            H +ALT+ G+++SWG G +GKLGHG+   +  P  IEAL+G  +  +SCG  HS+ V+  G  F +GN            N   P R   L    +  + CG + T  +S +   V+  G      +L   +   +  P  I+ L    C     I+K+A  +   + L  +G++Y+ G    +G  E   + H   +++  ++   + D+++   H + L  N  +Y+W   +E
Sbjct: 4093 HSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDG-DYGKLGLGNSTAKSSPQKIDVL----CGIG--IKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSE 4320

HSP 3 Score: 67.781 bits (164), Expect = 1.668e-9
Identity = 37/113 (32.74%), Postives = 65/113 (57.52%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW----GNPHAFNSKDENCLFPVRLRQAI----MSSIVCGPHSTFFLS 1735
            +H  A+T+ G+LY+WG G FG+LGHGD   ++ PTL++ +   N+  +SCG+SH+ A+S+ G   VW    G+       D N ++  ++ +A+    +  +  G  S+  L+
Sbjct:  521 RHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGSSHTIALSKDGRT-VWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALT 630

HSP 4 Score: 65.0846 bits (157), Expect = 1.004e-8
Identity = 31/70 (44.29%), Postives = 46/70 (65.71%), Query Frame = 2 
Query: 1418 SQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            S H +AL++ G+ ++S+GGG  GKLGHGD    + P +IEAL+G  IR +  G+  S A++ TG  + WG
Sbjct:  570 SSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWG 639

HSP 5 Score: 61.6178 bits (148), Expect = 1.106e-7
Identity = 31/71 (43.66%), Postives = 42/71 (59.15%), Query Frame = 2 
Query: 1379 IEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            IE +AVG      ++H LAL  +G +Y+WG  S G+LG G       PTL+  L+G N+R IS G  HS+A
Sbjct: 4293 IEDVAVG------AEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAA 4357

HSP 6 Score: 58.5362 bits (140), Expect = 1.021e-6
Identity = 26/68 (38.24%), Postives = 41/68 (60.29%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H   +T  G+L+++G G +G+LG G+  +K  P  + AL GY I  ++CG +H+ AVS  G   VW 
Sbjct: 4144 KHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADG-SMVWA 4210
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. UniProt/SwissProt
Match: sp|Q9VR91|HERC2_DROME (Probable E3 ubiquitin-protein ligase HERC2 OS=Drosophila melanogaster OX=7227 GN=HERC2 PE=1 SV=3)

HSP 1 Score: 80.1073 bits (196), Expect = 2.877e-13
Identity = 34/68 (50.00%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LALT  G+++SWG G  GKLGHG+      P L+EALR   IR+++CG+SHS+A+S  G  + WG
Sbjct: 3083 KHALALTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWG 3150

HSP 2 Score: 76.2554 bits (186), Expect = 3.780e-12
Identity = 30/68 (44.12%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LALT  G++Y+WG G  GKLGHG+ +    P L+E L G ++ +I+CG++HS+A++ +G    WG
Sbjct: 4146 KHCLALTTEGEVYAWGEGEDGKLGHGNRMSYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVLTWG 4213

HSP 3 Score: 62.7734 bits (151), Expect = 5.290e-8
Identity = 38/122 (31.15%), Postives = 57/122 (46.72%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPVRLRQAIMSSIV---CGPHSTFFLSINKRNVYY 1759
            S H  A+T  G + +WG G +G+LGHGD  D+  P L+EAL GY   +I+CG+  +  +  T    VW        K      + C  P ++       +V   CG  S F +++ K    Y
Sbjct: 4197 SAHSAAITASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGGSDGCKLPYKIESLAGLGVVKVECG--SQFSVALTKSGAVY 4316

HSP 4 Score: 62.3882 bits (150), Expect = 6.803e-8
Identity = 34/87 (39.08%), Postives = 51/87 (58.62%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILN---DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            KIE LA G  ++     SQ  +ALT+ G +Y+WG G F +LGHG +     P  + AL+G  I +I+ G+ H  A S++G  + WG+
Sbjct: 4287 KIESLA-GLGVVKVECGSQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGEVYTWGD 4372

HSP 5 Score: 62.003 bits (149), Expect = 7.780e-8
Identity = 37/146 (25.34%), Postives = 70/146 (47.95%), Query Frame = 2 
Query: 1187 LSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            LSC      ++++ C E ++++L+  G++ +  ++ P  +              P+   +V   +     G     + +H LA+  +   YSWG G   +LGHGD   +  PT I AL  + ++++ CG S+S+A++  G    WG
Sbjct:  568 LSC---RFQIKQVACCETQMLILSQEGKLYTWRLAKPEAE--------------PLPMEEVAHDVFISIAGH---CEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHARAVPTKIAALEQHCVQSVYCGCSYSAAITCGGNLLTWG 693

HSP 6 Score: 62.003 bits (149), Expect = 8.114e-8
Identity = 34/83 (40.96%), Postives = 46/83 (55.42%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            ++ Q+A G     D+Q  LALT+ G ++SWG G FGKLG G      +P  IE L G  +  I CGA  S A++  G  + WG
Sbjct: 3178 RVVQVACG---SRDAQ-TLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTWG 3256

HSP 7 Score: 58.151 bits (139), Expect = 1.139e-6
Identity = 26/70 (37.14%), Postives = 42/70 (60.00%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G++++WG G + +LGHG       P  I  LRG  + +++ GA H  AV++ G  + WG+
Sbjct: 3240 AQFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRGRRVIHVAVGALHCLAVTDAGQVYAWGD 3309
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. UniProt/SwissProt
Match: sp|O95714|HERC2_HUMAN (E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN=HERC2 PE=1 SV=2)

HSP 1 Score: 73.559 bits (179), Expect = 2.622e-11
Identity = 32/68 (47.06%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H  ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 3057 RHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWG 3124

HSP 2 Score: 67.0106 bits (162), Expect = 2.690e-9
Identity = 28/68 (41.18%), Postives = 43/68 (63.24%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +++ G +HS+ V+  G  + WG
Sbjct: 4049 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWG 4116

HSP 3 Score: 66.2402 bits (160), Expect = 4.232e-9
Identity = 29/75 (38.67%), Postives = 46/75 (61.33%), Query Frame = 2 
Query: 1412 NDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR----GYNIRNISCGASHSSAVSETGLGFVWG 1624
            +D  H LAL   G++YSWG G  G+LGHGD +    P +I A      G ++ +I+CG+++S+A++  G  + WG
Sbjct:  502 SDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWG 576

HSP 4 Score: 65.855 bits (159), Expect = 6.383e-9
Identity = 42/149 (28.19%), Postives = 73/149 (48.99%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGA--SHSSAVSETGLGFVWGN---PHAFNSKDENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGL 1840
            S +  A+T  G+LY+WG G++G+LGHG   D+  P L+  L+G  + +++CG+  + + AV+E G  + WG+           + C  P    +L+   +  + CG  S F +++ K    Y   +     L         YP ++EGL
Sbjct:  560 STYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCG--SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGL 706

HSP 5 Score: 63.929 bits (154), Expect = 2.118e-8
Identity = 27/70 (38.57%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV+++G  + WG+
Sbjct: 3214 AQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGD 3283

HSP 6 Score: 63.929 bits (154), Expect = 2.463e-8
Identity = 45/167 (26.95%), Postives = 76/167 (45.51%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
             +R++C K       +   +R+I C  +    L + G++ +  +       H +            N   +K K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F
Sbjct: 3082 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGD------------NTTQLKPKMVKVLLGHRVIQVACGSRDAQ-TLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYF 3235

HSP 7 Score: 62.3882 bits (150), Expect = 6.198e-8
Identity = 26/66 (39.39%), Postives = 40/66 (60.61%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW 1621
            H   +T  G LY+WG G +G+LGH D  D+  P L+EAL+G+ + +I+CG+  +  +  T    VW
Sbjct: 4102 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVW 4167

HSP 8 Score: 61.2326 bits (147), Expect = 1.508e-7
Identity = 38/113 (33.63%), Postives = 57/113 (50.44%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNP---HAFN----SKDENCLFPVRLRQAIMSSIVCGPHSTFFLS 1735
            SQ  +ALT+ GQ+YSWG G   +LGHG       P L+E L+G  + +++ G++H  A++E      WG+      F+    +K E    P  L    +  I CGP  +F  S
Sbjct:  666 SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALP-GLDTKHIVGIACGPAQSFAWS 777

HSP 9 Score: 59.6918 bits (143), Expect = 4.413e-7
Identity = 29/72 (40.28%), Postives = 41/72 (56.94%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T  GQ+Y+WG    G+ G+G       PTL++ L G  I  ++CG+SHS A
Sbjct: 3258 KIVHVAVG------ALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVA 3323

HSP 10 Score: 55.4546 bits (132), Expect = 8.523e-6
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 4206 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSK 4320
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. UniProt/SwissProt
Match: sp|Q4U2R1|HERC2_MOUSE (E3 ubiquitin-protein ligase HERC2 OS=Mus musculus OX=10090 GN=Herc2 PE=1 SV=3)

HSP 1 Score: 73.559 bits (179), Expect = 2.622e-11
Identity = 32/68 (47.06%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H  ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 3058 RHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWG 3125

HSP 2 Score: 67.0106 bits (162), Expect = 2.690e-9
Identity = 28/68 (41.18%), Postives = 43/68 (63.24%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +++ G +HS+ V+  G  + WG
Sbjct: 4051 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWG 4118

HSP 3 Score: 66.2402 bits (160), Expect = 4.232e-9
Identity = 29/75 (38.67%), Postives = 46/75 (61.33%), Query Frame = 2 
Query: 1412 NDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR----GYNIRNISCGASHSSAVSETGLGFVWG 1624
            +D  H LAL   G++YSWG G  G+LGHGD +    P +I A      G ++ +I+CG+++S+A++  G  + WG
Sbjct:  503 SDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWG 577

HSP 4 Score: 65.4698 bits (158), Expect = 7.872e-9
Identity = 42/149 (28.19%), Postives = 73/149 (48.99%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGA--SHSSAVSETGLGFVWGN---PHAFNSKDENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGL 1840
            S +  A+T  G+LY+WG G++G+LGHG   D+  P L+  L+G  + +++CG+  + + AV+E G  + WG+           + C  P    +L+   +  + CG  S F +++ K    Y   +     L         YP ++EGL
Sbjct:  561 STYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCG--SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGL 707

HSP 5 Score: 63.929 bits (154), Expect = 2.118e-8
Identity = 27/70 (38.57%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV+++G  + WG+
Sbjct: 3215 AQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGD 3284

HSP 6 Score: 63.929 bits (154), Expect = 2.463e-8
Identity = 45/167 (26.95%), Postives = 76/167 (45.51%), Query Frame = 2 
Query: 1178 LTRLSCSK-------ENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILN------DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
             +R++C K       +   +R+I C  +    L + G++ +  +       H +            N   +K K+ ++ +G  ++       D+Q  LALT  G ++SWG G FGKLG G     + P  IE L G  +  I CGA  S A++++G+ + WG    F
Sbjct: 3083 FSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGD------------NTTQLKPKMVKVLLGHRVIQVACGSRDAQ-TLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYF 3236

HSP 7 Score: 62.3882 bits (150), Expect = 7.148e-8
Identity = 26/66 (39.39%), Postives = 40/66 (60.61%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW 1621
            H   +T  G LY+WG G +G+LGH D  D+  P L+EAL+G+ + +I+CG+  +  +  T    VW
Sbjct: 4104 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVW 4169

HSP 8 Score: 61.2326 bits (147), Expect = 1.458e-7
Identity = 38/113 (33.63%), Postives = 57/113 (50.44%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNP---HAFN----SKDENCLFPVRLRQAIMSSIVCGPHSTFFLS 1735
            SQ  +ALT+ GQ+YSWG G   +LGHG       P L+E L+G  + +++ G++H  A++E      WG+      F+    +K E    P  L    +  I CGP  +F  S
Sbjct:  667 SQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALP-GLDSKHIVGIACGPAQSFAWS 778

HSP 9 Score: 59.6918 bits (143), Expect = 4.413e-7
Identity = 29/72 (40.28%), Postives = 41/72 (56.94%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            KI  +AVG      + H LA+T  GQ+Y+WG    G+ G+G       PTL++ L G  I  ++CG+SHS A
Sbjct: 3259 KIVHVAVG------ALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVA 3324

HSP 10 Score: 55.4546 bits (132), Expect = 8.523e-6
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 4208 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSK 4322
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. UniProt/SwissProt
Match: sp|Q4R828|RCCD1_MACFA (RCC1 domain-containing protein 1 OS=Macaca fascicularis OX=9541 GN=RCCD1 PE=2 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 2.642e-10
Identity = 35/88 (39.77%), Postives = 54/88 (61.36%), Query Frame = 2 
Query: 1361 PDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            P+++ +  QL +G      ++H L L   GQ++SWGGG  G+LGHG +  +  P L+EAL+G  +  ++ G  HS  VSETG  ++WG
Sbjct:  156 PELRAR--QLELG------AEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQGLTMAEVAAGGWHSVCVSETGDIYIWG 235
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. TrEMBL
Match: J9JPA7 (Uncharacterized protein OS=Acyrthosiphon pisum OX=7029 GN=100160819 PE=4 SV=2)

HSP 1 Score: 109.768 bits (273), Expect = 9.639e-20
Identity = 155/636 (24.37%), Postives = 283/636 (44.50%), Query Frame = 2 
Query: 1364 DVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVW--GNPHAFNSKDENCLFPVRLRQAI----MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHK-TFEKVQCMSRHKVFDISLSENHIVILGQN-VIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNT---SKYFEQI-----LPNTLK--------------LFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLL-KIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSN-NTLF----IKLFQLEFSKISDLLIAVCQNLSNYTINVLQ--NKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMNSI-IGCFKSYLLTAVKL--QKINQWIKGRGVEINLLLSKSPISWILFDVLNYLNEQHNLDILPLL 3145
            ++ CKI+Q++          H LAL+  G++YSWG G +GKLGHGD+     P LI+    G  I  +S G  HS+AV+  G  + W  G+       D N  F   L +++    +  + CG   T   S +   V+  GS     +L   + I  + P  IEGL      +  KI+K+A      + L   G +++ G G NLGC   +I   +   V+ + +  + DIS+ ++H + L +N  +Y+W    +     +    +S + +S  S     K+IN+   + ++    T + ++    P     ++ +S   FC  L  S   W      KY EQI      PN +               LF   +  + F+ L+   T      ++L   +LK+ D +     ++ ++  L+   S LL  +  +   +  +L+++ ++L+   +  L   + SLND S+ ++LF    + L++  +S I +++  + ++L+N T+ +L+  N   F +   LD     +I       +  + + +++   +F NS        CL   MN + +   ++YLL A K+    IN +     +  N +LS S +   + + LN L    +  I PL+
Sbjct:  420 NINCKIKQVSSSKGC---DGHSLALSDTGEVYSWGDGDYGKLGHGDVATHKEPKLIQGPFIGKVIELVSAGYRHSAAVTSDGQLYTWGEGDHGRLGHGDCNPRFIPTLVKSLSDMPVGYVACGSTHTLACSRDGNTVWSFGSG-DNGKLGHGNTIRLYKPQKIEGL------RHYKIKKVAAGIHFSVALTCTGEVFTWGQGSNLGCGSSEITLFSPAVVEDLMQQMIIDISVGDSHCLALTRNCAVYAWGSNGKG----QCGQGHSTSPVSRPS-----KVINLEGKQINQISAGTSHSVAWTTLPPDRQTNVWHSP--FCIDLHESTFKWLRQFIEKYCEQIESHESTPNDINEEMLILSLNMLNNHLFFARVSGHNFSKLLGNET------SQLRTLLLKLVDLQVKEVVERSLMDCLSTGASLLLPPLSGRLNILKSLLAQD-TNLTIGQKLLLDVTVSSLNDNSHISSLFRVNSMDLYENRYSSIEEVMKLLLKHLTNSTVTLLESNNSPTFKKVNKLD-----MILTSLHKLLLSHLLAYNIKSNHFSNS--------CLS--MNRLFVNHMEAYLLFANKIFTMAINSYKDEHHLFYNAVLSSSIVGETMINTLNSLTFLQSEHIQPLI 1012

HSP 2 Score: 70.4774 bits (171), Expect = 6.997e-8
Identity = 30/68 (44.12%), Postives = 46/68 (67.65%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            H LALT+ G+++SWG G FGKLGHG+   +  P LIE+L    +  ++CG  HS+ +S+ G  +V+G+
Sbjct: 3495 HSLALTETGEVFSWGDGDFGKLGHGNNERQRKPKLIESLYDVVVIQVACGHKHSAVLSQDGEVYVFGS 3562
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. TrEMBL
Match: A0A2S2PMV1 (Putative E3 ubiquitin-protein ligase OS=Schizaphis graminum OX=13262 GN=HERC1_1 PE=4 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 2.517e-18
Identity = 155/637 (24.33%), Postives = 284/637 (44.58%), Query Frame = 2 
Query: 1364 DVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVW--GNPHAFNSKDENCLFPVRLRQAI----MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHY-PSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHK-TFEKVQCMSRHKVFDISLSENHIVILGQN-VIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNT---SKYFEQI-----LPNTLK--------------LFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLL-KIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSN-NTLF----IKLFQLEFSKISDLLIAVCQNLSNYTINVLQ--NKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMNSI-IGCFKSYLLTAVKL--QKINQWIKGRGVEINLLLSKSPISWILFDVLNYLNEQHNLDILPLL 3145
            ++ CKI+Q++          H LAL+  G++YSWG G +GKLGHGD+     P LI+    G  I  +S G  HS+AV+  G  + W  G+       D N  F   L +++    +  + CG   T   S +   V+  GS   +N        L+ Y P  IEGL      +  KI+K+A      + L   G +++ G G NLGC   +I   +   V+ + +  + DIS+ ++H + L +N  +Y+W    +     +    +S + +S  S     K+IN+   + ++    T + ++    P     ++ +S   FC  L  S   W      KY EQI      PN +               LF   +  + F+ L+   T      ++L   +LK+ D +     ++ ++  L+   S LL  +  +   +  +L+++ ++L+   +  L   + SLND S+ ++LF    + L++  +S I +++  + ++L+N T+ +L+  N   F +   LD     II       +  + + +++   +F NS        CL   MN + +   ++YL+ A K+    I+ +     +  N +LS S +   + + LN L+   +  I PL+
Sbjct:  420 NINCKIKQVSSSKGC---DGHSLALSDTGEVYSWGDGDYGKLGHGDVATHKEPKLIQGPFIGKIIELVSAGYRHSAAVTSDGQLYTWGEGDHGRLGHGDCNPRFIPTLVKSLSDMPVGYVACGSTHTLACSRDGNTVWSFGS--GDNGKLGHGNTLRLYKPQKIEGL------RHYKIKKVAAGIHFSVALTCTGEVFTWGQGSNLGCGSSEITLFSPAVVEDLMQQIIIDISVGDSHCLALTRNCAVYAWGSNGKG----QCGQGHSTSPVSRPS-----KVINLEGKQINQISAGTSHSVAWTTLPPDRQTNVWHSP--FCIDLHESTFKWLRQFIEKYCEQIESHQSTPNDINEEMLILSLNMLNNHLFFARVSGHNFSKLLGNET------SQLRTLLLKLVDLQVKEVVERSLMDCLSTGASLLLPPLSGRLNILKSLLAQD-TNLTRGQKLLLDVTVSSLNDNSHISSLFRVNSMDLYENRYSSIEEVMKLLLKHLTNSTVTLLESNNYTIFKKGNKLD-----IILTSLHKLLLSHLLAYNIKSYHFSNS--------CLS--MNRLFVNHLEAYLMFANKIFTMAIDSYKDEHHIFYNAVLSSSIVGETMINTLNSLSFLQSEHIQPLI 1012

HSP 2 Score: 65.855 bits (159), Expect = 1.834e-6
Identity = 41/128 (32.03%), Postives = 63/128 (49.22%), Query Frame = 2 
Query: 1328 LFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFN-SKDENCLFPVRLRQAIMSSIV 1705
            L H   +P   P +   +  + VG+ +   S H LA ++ G  ++S+G G  GKLGHG+ L  + P  IE LR Y I+ ++ G   S A++ TG  F WG          E  LF   + + +M  I+
Sbjct:  511 LGHGDCNPRFIPTLVKSLSDMPVGY-VACGSTHTLACSRDGNTVWSFGSGDNGKLGHGNTLRLYKPQKIEGLRHYKIKKVAAGIHFSVALTCTGEVFTWGQGSNLGCGSSEITLFSPAVVEDLMQQII 637
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. TrEMBL
Match: A0A2S2QPE5 (Putative E3 ubiquitin-protein ligase OS=Sipha flava OX=143950 GN=HERC1_3 PE=4 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 3.244e-18
Identity = 130/526 (24.71%), Postives = 228/526 (43.35%), Query Frame = 2 
Query: 1364 DVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENC---LFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHK-TFEKVQCMSRHKVFDISLSENHIVILGQN-VIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNT---SKYFEQI-----LPNTLK--------------LFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSN-NTLF----IKLFQLEFSKISDLLIAVCQNLSNYTINVLQ--NKMNFNRSENLDESV 2827
            ++ CKI+Q++          H LAL+  G +YSWG G +GKLGHGD+     P LI+    G  I  +S G  HS+AV+  G  + WG          +C   L P     L    +  + CG   T   S +   V+  GS     +L   + +  + P  I+GL      +  KI+K+A      + L   G +++ G G NLGC   +I   +   V+ + +    DIS+ ++H + L +N  +Y+W    +     +    +S + +S  S     K+IN+   + ++    T + ++    P     ++ +S   FC  L  S   W      KY EQI      PN L               LF   +  + F+ L+   T      ++L   +LK+ D +     ++ ++  L+   S LL        I   L    ++L+   +  L   + SLND S+ ++LF    + L++  +  I +++  + ++L+N TI +L+  N   F +   L+E++
Sbjct:  420 NINCKIKQVSSSKGC---DGHSLALSDTGHVYSWGDGDYGKLGHGDVATHKEPKLIQGPFVGKVIELVSAGYRHSAAVTSDGQLYTWGEGDHGRLGHGDCNPRLIPTLVKSLSDMPVGYVACGSTHTLACSRDGNTVWSFGSG-DNGKLGHGNTLRLYKPQKIDGL------RHYKIKKVAAGIHFSVALACTGEVFTWGQGSNLGCGSSEITLFSPAVVEDLMQQMTIDISVGDSHCLALTRNCAVYAWGSNGKG----QCGQGHSTSPVSRPS-----KVINLEGKQINQISAGTSHSVAWTTLPPDRQTNVWHSP--FCIDLHESTFKWLRQFIEKYCEQIESHQSTPNDLNEEMLILSLNMLNNHLFFARVSGHDFSKLLGNET------SQLRTLLLKLVDLQVKEVVERSLMDCLSTGASLLLPPLSGRLSILKSLLAQETNLTTGQKLLLDVTVSSLNDNSHISSLFRVNSMDLYENRYLSIEEVMKLLLKHLTNSTITLLESNNYPAFKKGNKLNETL 918
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. TrEMBL
Match: A0A5E4MJB6 (Concanavalin A-like lectin/glucanase domain,WD40-repeat-containing domain,Regulator of chromosome OS=Cinara cedri OX=506608 GN=CINCED_3A017272 PE=4 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 4.072e-18
Identity = 145/616 (23.54%), Postives = 264/616 (42.86%), Query Frame = 2 
Query: 1364 DVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENC---LFPVRLR---QAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIH-KTFEKVQCMSRHKVFDISLSENHIVILGQN-VIYSWSLTAETFSFIEEPFDYSITAISSTSLINH--NKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILW---NTSKYFEQI-----LPN-----TLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSNNTLFIKL-----FQLEFSKISDLLIAVCQNLSNYTINVLQ--NKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFC-CLFPLMNSIIGCFKSYLLTAVKL--QKINQWIKGRGVEINLLLSKSPISWILFDVLNYL 3109
            +++CKI+Q++          H LAL+  G+++SWG G +GKLGHGD+     P LI+    G  +  +S G  HS+AV+  G  + WG          +C   L P  ++      +  + CG   T   S +   V+  GS     +L   + +  + P  I+GL +       KI+K+A      + L   G +++ G G NLGC   +I   +   V+ + +  + DIS+ ++H + L +N V+Y+W    +     +    +S + +S  S + H   K IN   +  S  +  T     +  N + S          FC  L  S   W      KY EQI      PN      L L L  + ++ F   +       +  ++L   +LK+ D +     ++ +++ L+   S LL   +    I   L    ++L+   +  L   + SLN+  + +   ++     +++ +  I +++  + ++L+N  I +L+  N  +  +   LD ++  +           Y+I  S +L Y   ++N   NFC C+  L    +   ++YLL A K+    I        +  N +LS S +   L + +N L
Sbjct:  419 NIECKIKQVSSSKGC---DGHSLALSDTGEVFSWGDGDYGKLGHGDVSTHKEPKLIQGPFIGKVVELVSAGYRHSAAVTSDGQLYTWGEGDHGRLGHGDCNPRLIPTLVKSLCDMPVGYVACGSTHTLACSRDGNTVWSFGSG-DNGKLGHGNTLRLYKPQKIDGLRYY------KIKKVAAGIHFSVALTCTGEVFTWGQGSNLGCGSSEITLYSPAVVEDLMQQMIIDISVGDSHCLALTRNCVVYAWGSNGKG----QCGQGHSTSPVSRPSKVIHLDGKQINQISAGTSHSVAWTTLPPDRKTNVWHSP---------FCIDLNESTFKWLRQCIEKYCEQIESHQYTPNDINEEMLILSLNMLTNHLFFARVSGHHFSGNETSQLRTLLLKLVDLQVKEVVERSLMKCLSTGASLLLPPLNGRLAILKSLLAQDTNLTKGQKMLLDITVSSLNENRHVSSLFRMSKKDSYEIRYLAIEEVMKLLLKHLTNSIITMLESNNYSSLKKGNKLDVTLTSL-----------YKILLSHLLAYNIKTNNFNDNFCPCMIRLF---VNHLETYLLFANKIFTMAITSHNYENHIFFNAVLSSSVVGETLINTINSL 997

HSP 2 Score: 71.2478 bits (173), Expect = 3.666e-8
Identity = 34/83 (40.96%), Postives = 51/83 (61.45%), Query Frame = 2 
Query: 1379 IEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            I QLA     +    H LALT+ G+++SWG G FGKLGHG+   +  P LIE+L    +  ++CG  HS+ +S+ G  +V+G+
Sbjct: 3462 ITQLATS---IGSDGHSLALTETGEVFSWGDGDFGKLGHGNNERQRKPKLIESLYDVVVIQVACGHKHSAVLSQDGEVYVFGS 3541
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. TrEMBL
Match: A0A5E4MP69 (Uncharacterized protein OS=Cinara cedri OX=506608 GN=CINCED_3A017272 PE=4 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 4.085e-18
Identity = 145/616 (23.54%), Postives = 264/616 (42.86%), Query Frame = 2 
Query: 1364 DVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENC---LFPVRLR---QAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIH-KTFEKVQCMSRHKVFDISLSENHIVILGQN-VIYSWSLTAETFSFIEEPFDYSITAISSTSLINH--NKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILW---NTSKYFEQI-----LPN-----TLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSNNTLFIKL-----FQLEFSKISDLLIAVCQNLSNYTINVLQ--NKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFC-CLFPLMNSIIGCFKSYLLTAVKL--QKINQWIKGRGVEINLLLSKSPISWILFDVLNYL 3109
            +++CKI+Q++          H LAL+  G+++SWG G +GKLGHGD+     P LI+    G  +  +S G  HS+AV+  G  + WG          +C   L P  ++      +  + CG   T   S +   V+  GS     +L   + +  + P  I+GL +       KI+K+A      + L   G +++ G G NLGC   +I   +   V+ + +  + DIS+ ++H + L +N V+Y+W    +     +    +S + +S  S + H   K IN   +  S  +  T     +  N + S          FC  L  S   W      KY EQI      PN      L L L  + ++ F   +       +  ++L   +LK+ D +     ++ +++ L+   S LL   +    I   L    ++L+   +  L   + SLN+  + +   ++     +++ +  I +++  + ++L+N  I +L+  N  +  +   LD ++  +           Y+I  S +L Y   ++N   NFC C+  L    +   ++YLL A K+    I        +  N +LS S +   L + +N L
Sbjct:  242 NIECKIKQVSSSKGC---DGHSLALSDTGEVFSWGDGDYGKLGHGDVSTHKEPKLIQGPFIGKVVELVSAGYRHSAAVTSDGQLYTWGEGDHGRLGHGDCNPRLIPTLVKSLCDMPVGYVACGSTHTLACSRDGNTVWSFGSG-DNGKLGHGNTLRLYKPQKIDGLRYY------KIKKVAAGIHFSVALTCTGEVFTWGQGSNLGCGSSEITLYSPAVVEDLMQQMIIDISVGDSHCLALTRNCVVYAWGSNGKG----QCGQGHSTSPVSRPSKVIHLDGKQINQISAGTSHSVAWTTLPPDRKTNVWHSP---------FCIDLNESTFKWLRQCIEKYCEQIESHQYTPNDINEEMLILSLNMLTNHLFFARVSGHHFSGNETSQLRTLLLKLVDLQVKEVVERSLMKCLSTGASLLLPPLNGRLAILKSLLAQDTNLTKGQKMLLDITVSSLNENRHVSSLFRMSKKDSYEIRYLAIEEVMKLLLKHLTNSIITMLESNNYSSLKKGNKLDVTLTSL-----------YKILLSHLLAYNIKTNNFNDNFCPCMIRLF---VNHLETYLLFANKIFTMAITSHNYENHIFFNAVLSSSVVGETLINTINSL 820

HSP 2 Score: 71.2478 bits (173), Expect = 4.321e-8
Identity = 34/83 (40.96%), Postives = 51/83 (61.45%), Query Frame = 2 
Query: 1379 IEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            I QLA     +    H LALT+ G+++SWG G FGKLGHG+   +  P LIE+L    +  ++CG  HS+ +S+ G  +V+G+
Sbjct: 3285 ITQLATS---IGSDGHSLALTETGEVFSWGDGDFGKLGHGNNERQRKPKLIESLYDVVVIQVACGHKHSAVLSQDGEVYVFGS 3364
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Cavefish
Match: herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:ZFIN;Acc:ZDB-GENE-070718-6])

HSP 1 Score: 75.0998 bits (183), Expect = 1.094e-12
Identity = 32/68 (47.06%), Postives = 48/68 (70.59%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H +ALT  G+++SWG G  GKLGH   ++   P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 3050 RHAMALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYSWG 3117

HSP 2 Score: 73.9442 bits (180), Expect = 2.531e-12
Identity = 48/146 (32.88%), Postives = 76/146 (52.05%), Query Frame = 2 
Query: 1214 VREIICSENEIIVLNNLGQI-----RSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR----GYNIRNISCGASHSSAVSETGLGFVWG 1624
            V +I+CSE   ++L+  G +     +S ++SP          ML H   S         KI +LA       + QH LAL+ +G+++SWG G  G+LGHGD      PT+I A      G ++ +I+CG+++S+A++  G  F WG
Sbjct:  452 VTQIVCSEKGFLILSISGAVYTQNYKSTTLSP----------MLVHGLSSR--------KIVKLAAH----PEGQHYLALSANGEVFSWGCGDGGRLGHGDTTYLEEPTMIAAFSGKQVGKHVVHIACGSTYSAAITADGELFTWG 575

HSP 3 Score: 71.633 bits (174), Expect = 1.278e-11
Identity = 49/163 (30.06%), Postives = 78/163 (47.85%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGA--SHSSAVSETGLGFVWGN---PHAFNSKDENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGL 1840
            +I  +A G      S H  A+T  G+LYSWG G +G+LGHGD   +  P L++ L G+ +  ++CG+  + + A+++ GL F WG+           E C  P    RL    +  I CG  + F L++ K  V +   +     L     +    P ++EGL
Sbjct: 3093 RIRDIACG------SSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECG--AQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQMVEGL 3247

HSP 4 Score: 68.1662 bits (165), Expect = 1.252e-10
Identity = 30/70 (42.86%), Postives = 45/70 (64.29%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LALT+ G +++WG G + +LGHG  +    P ++E LRG  I +++ GA H  AV+ETG  F WG+
Sbjct: 3207 AQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQMVEGLRGKKIVHVAVGALHCLAVTETGQVFAWGD 3276

HSP 5 Score: 68.1662 bits (165), Expect = 1.431e-10
Identity = 28/68 (41.18%), Postives = 44/68 (64.71%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+      P +IE+LRG  + +I+ G +HS+ ++ +G  + WG
Sbjct: 4044 KHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGVEVVDIAAGGAHSACITASGELYTWG 4111

HSP 6 Score: 65.0846 bits (157), Expect = 1.108e-9
Identity = 25/66 (37.88%), Postives = 42/66 (63.64%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW 1621
            H   +T  G+LY+WG G +G+LGHGD  D+  P L++AL+G+ + +++CG+  +  +  T    VW
Sbjct: 4097 HSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVDALQGHRVIDVACGSGDAQTLCLTDDDMVW 4162

HSP 7 Score: 65.0846 bits (157), Expect = 1.215e-9
Identity = 26/68 (38.24%), Postives = 45/68 (66.18%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW 1621
            S +  A+T  G+L++WG G++G+LGHG   D+ +P L+ AL+G  + +++CG+  +  +S T  G VW
Sbjct:  559 STYSAAITADGELFTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLSVTENGQVW 626

HSP 8 Score: 62.7734 bits (151), Expect = 5.834e-9
Identity = 37/113 (32.74%), Postives = 59/113 (52.21%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHA-------FNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLS 1735
            SQ  +ALT+ GQ+Y+WG G   +LGHG       P L+++L+G  + +I+ G++H  A++E G    WG+          F++K +    P  L    +  I CGP  +F  S
Sbjct:  665 SQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSLQGKKVVDIAVGSTHCLALTEDGEVHSWGSNDKLQHFDTLFSNKKQPKALP-GLNSKHIVGISCGPGQSFAWS 776

HSP 9 Score: 55.4546 bits (132), Expect = 8.436e-7
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG       P  ++ L+G  +  I+ G+ H    +E G  + WG+       D   N +   RL  A+    ++ + CG   T   S +K
Sbjct: 4201 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSK 4315

HSP 10 Score: 52.7582 bits (125), Expect = 5.476e-6
Identity = 25/70 (35.71%), Postives = 39/70 (55.71%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            D+Q  L LT    ++SWG G +GKLG G       P  I++L G  +  + CG+  S A++++G  + WG
Sbjct: 4149 DAQ-TLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWG 4217
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Cavefish
Match: ENSAMXT00000005642.2 (pep primary_assembly:Astyanax_mexicanus-2.0:25:4946095:4960001:-1 gene:ENSAMXG00000005499.2 transcript:ENSAMXT00000005642.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.5514 bits (166), Expect = 6.020e-11
Identity = 67/241 (27.80%), Postives = 108/241 (44.81%), Query Frame = 2 
Query: 1151 LKAPYNDSLLT-RLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHG--DMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG--NPHAFNSKDEN------CLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGL 1840
            ++AP    L   RL   +    +R + C EN+ ++L N G++                +  ++ C SPI +   +  I Q+A G       QH +ALT  GQL++WG  S G+LG G  D     SP  ++++ G  +  IS G  HS A+S +G+ F WG  N       D        C+  +  ++ ++  I CG   T  L+ +   V+  GS C   +L    F  +  P ++ GL
Sbjct:   69 IRAPPTGGLQGGRLKKLELKDKIRSMSCGENDAVLLTNEGKVFQ--------------LNKYNIC-SPIKYLADRTVI-QIACG------DQHCMALTDDGQLFTWGQNSSGQLGLGKKDESSSQSPQPLKSMTGIPLAQISAGGDHSFALSLSGVVFGWGRNNTGQLGLGDREDRYVPVCVKSLNRKKTVL--ISCGEDHTAVLTKDGL-VFTFGSGCY-GQLGHNSFSDELRPRLLGGL 283

HSP 2 Score: 60.077 bits (144), Expect = 2.767e-8
Identity = 52/205 (25.37%), Postives = 88/205 (42.93%), Query Frame = 2 
Query: 1205 NHSVREIICSENEIIVLNNLGQI----RSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAIM--------SSIVCGPHSTFFLSINKRNVYYLGSQCSEN 1783
            + +V +I C +   + L + GQ+    ++ S      KK E+         S    P     + Q++ G        H  AL+  G ++ WG  + G+LG GD  D++ P  +++L       ISCG  H++ +++ GL F +G+   +     N  F   LR  ++        S I CG H T  L  + + +Y  G  C E 
Sbjct:  127 DRTVIQIACGDQHCMALTDDGQLFTWGQNSSGQLGLGKKDESSSQSPQPLKSMTGIP-----LAQISAG------GDHSFALSLSGVVFGWGRNNTGQLGLGDREDRYVPVCVKSLNRKKTVLISCGEDHTAVLTKDGLVFTFGS-GCYGQLGHNS-FSDELRPRLLGGLWGSEVSQIACGRHHTLALVGSSKTIYSFG--CGEQ 316
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Cavefish
Match: ENSAMXT00000020522.2 (pep primary_assembly:Astyanax_mexicanus-2.0:25:7552218:7569483:1 gene:ENSAMXG00000019935.2 transcript:ENSAMXT00000020522.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.4698 bits (158), Expect = 5.423e-10
Identity = 63/221 (28.51%), Postives = 99/221 (44.80%), Query Frame = 2 
Query: 1139 KLETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDV---KCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN--------PHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGS 1768
            +L  L+AP   ++   L   ++   +R + C E + ++L + G+                 V+L  Q    +NF  +     K+ Q+A G      +QH +ALT  GQL++WG  S G+LG G     +SP  + +LRG  +  IS G  HS A+S +G  F WG          +A N     C+  + L++ +   I CG   T  LS     V+  GS
Sbjct:   62 RLTPLEAPSEKTIPESLELKEK---IRLMSCGETQAVLLADGGK-----------------VLLMDQ----LNFCRLILSGTKVIQVACG------NQHCMALTHDGQLFTWGENSSGQLGLGSG-KSNSPQPLRSLRGIPLAQISAGGDHSFALSLSGTVFGWGRNNAGQLGLGNAENRSTPACVNHLNLKKTVF--ISCGEDHTATLS-KGGTVFTFGS 248

HSP 2 Score: 51.6026 bits (122), Expect = 9.459e-6
Identity = 44/162 (27.16%), Postives = 72/162 (44.44%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAI--------MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIA 1885
            H  AL+  G ++ WG  + G+LG G+  ++ +P  +  L       ISCG  H++ +S+ G  F +G+   F     N  F   LR  +        +S I CG + T  L  +   VY  G Q    +        Q  P  ++ LP  + +  ++IE+IA
Sbjct:  181 HSFALSLSGTVFGWGRNNAGQLGLGNAENRSTPACVNHLNLKKTVFISCGEDHTATLSKGGTVFTFGSGR-FGQLGHNS-FRDELRPRVVAALWGSKVSQITCGRNHTLALVSSSNTVYSFGWQLGNGQQTN-----QCVPLPVDLLP--ESNHGQEIEQIA 333
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Cavefish
Match: ENSAMXT00000051376.1 (pep primary_assembly:Astyanax_mexicanus-2.0:14:34371659:34376141:-1 gene:ENSAMXG00000039511.1 transcript:ENSAMXT00000051376.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 57.3806 bits (137), Expect = 1.892e-9
Identity = 30/67 (44.78%), Postives = 41/67 (61.19%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            H LALT+ G+++SWG G +GKLGHG+   +  P  IE   G  I +I+ G  H  A+S TG  + WG
Sbjct:   25 HSLALTETGEVFSWGDGDYGKLGHGNSERQRRPKQIE---GIFIEDIAVGCEHILALSSTGDVYAWG 88
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Cavefish
Match: rccd1 (RCC1 domain containing 1 [Source:NCBI gene;Acc:103040546])

HSP 1 Score: 61.6178 bits (148), Expect = 5.371e-9
Identity = 26/69 (37.68%), Postives = 43/69 (62.32%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            ++H + LT  G +Y+WG GS G+LG G ++ +  P  +EAL G  + ++S G  HS+ +S  G  ++WG
Sbjct:  191 TEHAVLLTTSGTVYTWGSGSHGQLGQGSVVSEDEPRAVEALWGVPMNHVSAGGWHSACISAGGDLYIWG 259
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001275.1 (pep scaffold:Pmarinus_7.0:GL476529:184068:212443:-1 gene:ENSPMAG00000001140.1 transcript:ENSPMAT00000001275.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 82.0333 bits (201), Expect = 1.435e-15
Identity = 70/231 (30.30%), Postives = 107/231 (46.32%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEA-LRGYNIRNISCGASHSSAVSETGLGFVWGNPH--AFNSKDENCLFPVRLRQAI--MSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQI----HKTFEKVQCMSRHKVFDISLSENHIVILGQ-NVIYSW 2086
            H LA+T  G+++SWG G +GKLGHG+   +  P LI+  L+G  +  +S G  HS++V+E G  + WG          D N      L + I  +  + CG   T  +S + R V+  G      +L   D    + P +IE L      +   I K+   S   L L + G LY+ G G  LGC   +      K  E + C    ++ DIS  ++H + L   N +Y+W
Sbjct:  476 HTLAVTMEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSASVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGQVACGSSHTIAVSQDGRIVWSFGGG-DNGKLGHGDTNRVYKPKVIEAL------QGMFIRKVCAGSQSSLALTSTGQLYAWGCGACLGCGSSEATALRPKLIEDLACT---RIVDISCGDSHCLALTHDNEVYAW 696

HSP 2 Score: 63.1586 bits (152), Expect = 7.386e-10
Identity = 34/83 (40.96%), Postives = 51/83 (61.45%), Query Frame = 2 
Query: 1379 IEQLAVGWPILNDSQHILALTQHGQL-YSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            + Q+A G      S H +A++Q G++ +S+GGG  GKLGHGD    + P +IEAL+G  IR +  G+  S A++ TG  + WG
Sbjct:  570 VGQVACG------SSHTIAVSQDGRIVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQLYAWG 646
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Sea Lamprey
Match: rcc2 (regulator of chromosome condensation 2 [Source:NCBI gene;Acc:406455])

HSP 1 Score: 60.8474 bits (146), Expect = 1.982e-9
Identity = 40/128 (31.25%), Postives = 61/128 (47.66%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPH----AFNSKDENCLFPVRLRQAIMSS-----IVCGPHSTFFLSINKRNVYYLGSQCSE 1780
            H L LT  GQ+Y+WG G  G+LGHGD+    +P  ++AL    +   +CG SH+  ++ETG+   +G  H       +K      P   +Q + S      + CG   +  +   K N+Y  G  C E
Sbjct:   65 HCLLLTDLGQVYTWGRGDKGQLGHGDLKRVEAPRPVDALFKLTVVAAACGRSHTLCITETGVVMAFGENHLGQLGLGTKSNAMPTP---KQIVYSGQPVVKVACGAEFSMLVDC-KGNLYSFG--CPE 186
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001750.1 (pep scaffold:Pmarinus_7.0:GL481695:1137:12922:1 gene:ENSPMAG00000001576.1 transcript:ENSPMAT00000001750.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.9214 bits (141), Expect = 1.193e-8
Identity = 31/64 (48.44%), Postives = 36/64 (56.25%), Query Frame = 2 
Query: 1436 LTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            LT  G L ++G GS G LGHG   D   P ++EAL GY I  +SCG SH  AVS     F WG 
Sbjct:  327 LTDRGILMTYGSGSSGCLGHGSYSDVAQPKIVEALLGYEITQMSCGMSHVLAVSNEQEVFAWGR 390

HSP 2 Score: 51.6026 bits (122), Expect = 1.874e-6
Identity = 47/195 (24.10%), Postives = 85/195 (43.59%), Query Frame = 2 
Query: 1187 LSCSKENHSVREIICSENEIIVLNNLGQIR----SRSISPPSTKKHENIVMLFHQCWSPI-NFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNP---HAFNSKDENCL-FPVRLRQAIMSSI--VCGPHSTFFLSI 1738
            + CS    S + + C  N     N LG  +        + P+ +  E++V+      SP+ + P    ++  +A+G      + H  A+T  G  Y++G    G+LG G      +P  ++ L G  +  ++CG + + AV+E G  F WG         +  E C+  PV+L++    ++  V   H    LS+
Sbjct:  425 IDCSMVTSSGKLLACGSNR--RYNKLGLDKISHDGDDAACPAEQTEESLVL------SPVQSSPLDGARVVHVALG------TAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSRAPQPVDGLGGVKVVQVTCGDAFTVAVAEGGQVFTWGKAARGRLGRTDGEACVPGPVQLQERFPYAVTSVSSRHGNTLLSV 605
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002333.1 (pep scaffold:Pmarinus_7.0:GL483648:23119:25960:-1 gene:ENSPMAG00000002127.1 transcript:ENSPMAT00000002333.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.9878 bits (123), Expect = 2.950e-7
Identity = 48/195 (24.62%), Postives = 85/195 (43.59%), Query Frame = 2 
Query: 1187 LSCSKENHSVREIICSENEIIVLNNLGQIR----SRSISPPSTKKHENIVMLFHQCWSPI-NFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNP---HAFNSKDENCL-FPVRLRQAIMSSI--VCGPHSTFFLSI 1738
            + CS    S R + C  N     N LG  +        + P+ +  E++V+      SP+ + P    ++  +A+G      + H  A+T  G  Y++G    G+LG G      +P  ++ L G  +  ++CG + + AV+E G  F WG         +  E C+  PV+L++    ++  V   H    LS+
Sbjct:   32 IDCSMVTSSGRLLACGSNR---YNKLGLDKISHDGDDAACPAEQTEESLVL------SPVQSSPLDGARVVHVALG------TAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSRAPQPVDGLGGVKVVQVTCGDAFTVAVAEGGQVFTWGKAARGRLGRTDGEACVPGPVQLQETFPYAVTSVSSRHGNTLLSV 211
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002332.1 (pep scaffold:Pmarinus_7.0:GL483648:174:5242:1 gene:ENSPMAG00000002120.1 transcript:ENSPMAT00000002332.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 52.373 bits (124), Expect = 4.045e-7
Identity = 47/195 (24.10%), Postives = 85/195 (43.59%), Query Frame = 2 
Query: 1187 LSCSKENHSVREIICSENEIIVLNNLGQIR----SRSISPPSTKKHENIVMLFHQCWSPI-NFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNP---HAFNSKDENCL-FPVRLRQAIMSSI--VCGPHSTFFLSI 1738
            + CS    S R + C  N     N LG  +        + P+ +  E++V+      SP+ + P    ++  +A+G      + H  A+T  G  Y++G    G+LG G      +P  ++ L G  +  ++CG + + A++E G  F WG         +  E C+  PV+L++    ++  V   H    LS+
Sbjct:   72 IDCSMVTSSGRLLACGSNR---YNKLGLDKISHDGDDAACPAEQTEESLVL------SPVQSSPLDGARVVHVALG------TAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSRAPQPVDGLGGVKVVQVTCGDAFTVAIAEGGQVFTWGKAARGRLGRTDGEACVPGPVQLQETFPYAVTSVSSRHGNTLLSV 251
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Nematostella
Match: EDO45579 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSK3])

HSP 1 Score: 88.9669 bits (219), Expect = 1.672e-17
Identity = 73/229 (31.88%), Postives = 108/229 (47.16%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIR-NISCGASHSSAVSETGLGFVWGNPH--AFNSKDENCL-FPVRLRQ-AIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEK-VQCMSRHKVFDISLSENHIVILGQ-NVIYSWS 2089
            H LALT  G++YSWG G +GKLGHG+   +  P L+E   G  +   I+ G  HS+AV+E G  + WG          D N    PV+++  A +  + CG   T  +S + + V+  GS     +L   D    + P +IE L      +   I K+   S   L L + G +Y  G G +LG           K +  +  H V DIS+ ++H V L Q N +Y+W 
Sbjct:  461 HTLALTLDGKVYSWGDGDYGKLGHGNSQTQKIPKLVEGALGNKVVCCIAAGYRHSAAVTEDGELYTWGEGDYGRLGHGDNNSRNVPVQVKDVANVGQVACGSAHTVCVSQDGQTVWSFGSG-DNGKLGHSDTNRVYKPKVIEAL------QGMVIRKVCCGSQCSLALTSTGQVYVWGCGPSLGTGSVDATSATPKLLLALQSHSVVDISVGDSHCVALTQDNNVYAWG 682

HSP 2 Score: 65.0846 bits (157), Expect = 3.575e-10
Identity = 37/93 (39.78%), Postives = 54/93 (58.06%), Query Frame = 2 
Query: 1349 PINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            P+   DV   + Q+A G      S H + ++Q GQ ++S+G G  GKLGH D    + P +IEAL+G  IR + CG+  S A++ TG  +VWG
Sbjct:  546 PVQVKDVA-NVGQVACG------SAHTVCVSQDGQTVWSFGSGDNGKLGHSDTNRVYKPKVIEALQGMVIRKVCCGSQCSLALTSTGQVYVWG 631
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Nematostella
Match: EDO37196 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGI6])

HSP 1 Score: 86.6557 bits (213), Expect = 1.162e-16
Identity = 47/120 (39.17%), Postives = 66/120 (55.00%), Query Frame = 2 
Query: 1370 KCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPH---AFNSKDENCLFPVR---LRQAIMSSIVCG 1711
            KC+I Q+        D +H LALT+ G++YSWG G  GKLGHGD   +  PTL+  L G  +  ISCG++HS+AV+  G  + WG  +     +   E+ L PV    LR   +  + CG
Sbjct:   14 KCEIVQVVTH----TDGKHFLALTREGEVYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACG 129

HSP 2 Score: 74.3294 bits (181), Expect = 6.821e-13
Identity = 30/68 (44.12%), Postives = 47/68 (69.12%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H +ALT  G+L+SWG G  GKLGHG+ ++   P LI+  +   +R++SCG+SHS+A+  +G  + WG
Sbjct: 2519 RHAMALTIEGKLFSWGEGEDGKLGHGNRMNCDHPKLIDTFKSSCVRDMSCGSSHSAAILSSGELYTWG 2586

HSP 3 Score: 72.0182 bits (175), Expect = 3.168e-12
Identity = 31/68 (45.59%), Postives = 44/68 (64.71%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H +AL+  G +YSWG G  GKLGHG+      P +IEALRG  + +ISCG SHS+ +++    + WG
Sbjct: 3451 KHAMALSADGDVYSWGEGDDGKLGHGNRNSCDRPRVIEALRGKGVIDISCGGSHSACITQNHELYTWG 3518

HSP 4 Score: 70.4774 bits (171), Expect = 8.671e-12
Identity = 29/72 (40.28%), Postives = 49/72 (68.06%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGA--SHSSAVSETGLGFVWGN 1627
            S H  A+T  G+LY+WG G++G+LGHG   D+  P L+  LRG++I +++CG+  +H+ A ++ G  + WG+
Sbjct:   78 STHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGD 149

HSP 5 Score: 66.6254 bits (161), Expect = 1.371e-10
Identity = 36/120 (30.00%), Postives = 62/120 (51.67%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPVRLRQAI---MSSIVCGPHSTFFLSINKRNVYY 1759
            H   +TQ+ +LY+WG G +G+LGHGD  D+  P ++EALRG  + +++CG+  +  +  T    VW        K      + C  P+++   I   +S + CG  S F +++ +    Y
Sbjct: 3504 HSACITQNHELYTWGKGRYGRLGHGDSEDQLLPKVVEALRGNRVIDVACGSGDAQTLCLTDDDCVWSWGDGDYGKLGRGGSDGCKIPMKVESLIGLGVSKVECG--SQFSVALTRSGAVY 3621

HSP 6 Score: 62.7734 bits (151), Expect = 2.279e-9
Identity = 31/70 (44.29%), Postives = 42/70 (60.00%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            D+Q  LALT  G ++SWG G FGKLG G       P  +E L+G  +  ++CGA  S A+S +GL + WG
Sbjct: 2624 DAQ-TLALTDDGTVWSWGDGDFGKLGRGGSEGCSVPNPVEKLQGQGVCKVACGAQFSLALSTSGLVWTWG 2692

HSP 7 Score: 62.3882 bits (150), Expect = 3.082e-9
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            +Q  LAL+  G +++WG G + +LGHG+      P +++ LRG  I +++ GA H  AV+++G  F WG+
Sbjct: 2676 AQFSLALSTSGLVWTWGKGDYYRLGHGNDTHVRKPQIVDGLRGKKIVDVAVGALHCLAVTDSGQVFAWGD 2745

HSP 8 Score: 61.6178 bits (148), Expect = 4.275e-9
Identity = 36/114 (31.58%), Postives = 57/114 (50.00%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAIMS--------SIVCGPHSTFFLS 1735
            +Q  LALT+ G +++WG G   +LGHG       P L+EAL G ++ ++S G+ H  A+++ G  + WG        D +C   +R    ++S         I CGP  +F  S
Sbjct:  184 AQFSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGDIDC--QIRPEPTLVSGLASKGIVGIACGPAQSFAWS 295

HSP 9 Score: 58.9214 bits (141), Expect = 2.920e-8
Identity = 39/117 (33.33%), Postives = 59/117 (50.43%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKH--SPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKD--ENCLFPVRLRQAI----MSSIVCGPHSTFFLSINK 1744
            SQ  +ALT+ G +Y+WG G + +LGHG  +D H   P  + AL+G  +  I+ G+ H  A ++TG  + WG+       D   N +   RL  A+    +S + CG   T   S  K
Sbjct: 3608 SQFSVALTRSGAVYTWGKGDYYRLGHG--VDDHVRRPKRVAALQGKKVITIATGSLHCVASTDTGEVYTWGDNDEGQLGDGTTNAIARPRLVTALQGKKISRVACGSAHTIAWSTCK 3722

HSP 10 Score: 57.3806 bits (137), Expect = 9.139e-8
Identity = 23/68 (33.82%), Postives = 39/68 (57.35%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVW 1621
            S H  A+   G+LY+WG G +G+LGHGD      P  +++   + + +I+CG+  +  ++ T  G VW
Sbjct: 2570 SSHSAAILSSGELYTWGLGEYGRLGHGDNYTHLKPKKVQSFTSHRVIDIACGSRDAQTLALTDDGTVW 2637

HSP 11 Score: 56.9954 bits (136), Expect = 1.216e-7
Identity = 27/72 (37.50%), Postives = 37/72 (51.39%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAF 1639
            H LA    G ++SWG G +GKLG G      +P  IE L+G  +  + CGA  S A++  G  + WG    F
Sbjct:  134 HTLAAADDGTVWSWGDGDYGKLGRGGSDGCKNPKSIERLQGLGVCKVYCGAQFSLALTRDGSVWTWGKGEGF 205

HSP 12 Score: 54.6842 bits (130), Expect = 5.985e-7
Identity = 28/78 (35.90%), Postives = 42/78 (53.85%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGL 1609
            KI  +AVG      + H LA+T  GQ+++WG    G+ G+        P L+  L G  I  ++CG+SHS A +E+ L
Sbjct: 2720 KIVDVAVG------ALHCLAVTDSGQVFAWGDNDHGQQGNNTTTVNRRPQLVNGLEGQKITRVACGSSHSIAWAESDL 2791

HSP 13 Score: 51.9878 bits (123), Expect = 3.886e-6
Identity = 25/70 (35.71%), Postives = 38/70 (54.29%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            D+Q  L LT    ++SWG G +GKLG G       P  +E+L G  +  + CG+  S A++ +G  + WG
Sbjct: 3556 DAQ-TLCLTDDDCVWSWGDGDYGKLGRGGSDGCKIPMKVESLIGLGVSKVECGSQFSVALTRSGAVYTWG 3624
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Nematostella
Match: EDO45583 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSK9])

HSP 1 Score: 85.1149 bits (209), Expect = 2.514e-16
Identity = 85/335 (25.37%), Postives = 146/335 (43.58%), Query Frame = 2 
Query: 1112 DIYIWEHGRKLETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN------PHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIH--KTFEKVQCMSRHKVFDISLSENHIVIL-GQNVIYSWS 2089
            D Y+W  GR  +  ++    ++ T    +K   S ++++C +N   V+   G I +            N   LF    SPI+       I Q+A          H LALT  G+++SWG G +GKLGHG+   +  P  IEALRG  + N++CG  HS+ V+  G  F +GN       H  ++  +       L +  +  + CG + T  LS +   V+  G      +L       +  P  I+ L    C      +KI   +   +VL N+G ++S G     G  E ++   +  +++Q ++ H + D+ +   H++ L     ++ W 
Sbjct:  489 DAYLWGGGRHGQLAESGRGVNVPT---VTKSLASAQQVVCGQNCTFVVQVNGTILACGEGSYGRLGMGNSDDLF--TLSPISALQGYVVI-QIATS---RGSDGHSLALTDSGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALRGEEVVNMACGFKHSAVVTVDGKLFTFGNGDYGRLGHGNSANKKTPERVTALEKHAIGQVACGLNHTLVLSADGNTVWAFGDG-DYGKLGLGSCTAKTSPQAIDVLAGIGC------KKICCGTQFSVVLTNDGRVFSFGQERLTGQPEGRLRGPQKPQQIQALASHFIDDVCVGAEHVLALTSTGEVWGWG 807

HSP 2 Score: 54.299 bits (129), Expect = 6.155e-7
Identity = 25/58 (43.10%), Postives = 37/58 (63.79%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            ++H+LALT  G+++ WG    G+LG G    +  P +I  L+G NIR IS G +HS+A
Sbjct:  791 AEHVLALTSTGEVWGWGNNVDGQLGLGHSNAQREPCVIPDLKGKNIRQISAGRNHSAA 848
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Nematostella
Match: EDO44704 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV05])

HSP 1 Score: 70.0922 bits (170), Expect = 2.990e-12
Identity = 51/188 (27.13%), Postives = 83/188 (44.15%), Query Frame = 2 
Query: 1169 DSLLTRLSCSKENHSVREIICSENEIIVLN-----NLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN-PHAFNSKDENCLFPVRLR-QAIMSSIVCG 1711
            D  +  LSC  E+ +V   + +  ++          LG   ++S + PS  K                    K K E++   + +     H +A T+ G LYS+G G  G+LGHGD  D H P +IE L     ++++CG+  S+A++E G  + WG+     N   E+   P RL     +  + CG
Sbjct:   34 DDAVVNLSCGDEHSAV---VTANGKLYTFGCNDWGQLGHGNTKSYTKPSVVK--------------------KLKPEKV---YMVACGRNHTIAATESGHLYSFGCGGDGQLGHGDAEDSHVPKIIEGLDVQKYKHLACGSDFSAAITENGELYTWGSCGEGQNGLGEDTEIPTRLHLHGKVRMVSCG 195
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Nematostella
Match: EDO46528 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPL2])

HSP 1 Score: 58.5362 bits (140), Expect = 7.504e-10
Identity = 39/136 (28.68%), Postives = 62/136 (45.59%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCL-------FP-VRLRQAIMS----SIVCGPHSTFFLSINKRNVYYLGSQCSENELFT 1795
            H+  +T     Y+WG  S G+LG GD++++  PTL++ L+G  I    CG   S  V++ G+    G      S D  CL        P  +L + ++S    ++ CGPH             ++   CSE  +FT
Sbjct:    7 HVAVVTLERAAYTWGDNSRGQLGQGDLVNRDKPTLVDTLKGKAITRACCGDKFSVFVTDNGIVMTCG------SSDTGCLGHGDWSSTPRPKLIEGLLSVDVTAVSCGPH-------------HVAVVCSEGLVFT 123

HSP 2 Score: 50.8322 bits (120), Expect = 4.285e-7
Identity = 24/63 (38.10%), Postives = 32/63 (50.79%), Query Frame = 2 
Query: 1436 LTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +T +G + + G    G LGHGD      P LIE L   ++  +SCG  H + V   GL F WG
Sbjct:   63 VTDNGIVMTCGSSDTGCLGHGDWSSTPRPKLIEGLLSVDVTAVSCGPHHVAVVCSEGLVFTWG 125
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Medaka
Match: herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:NCBI gene;Acc:101167612])

HSP 1 Score: 72.0182 bits (175), Expect = 9.072e-12
Identity = 57/198 (28.79%), Postives = 89/198 (44.95%), Query Frame = 2 
Query: 1214 VREIICSENEIIVLNNLGQI-----RSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR----GYNIRNISCGASHSSAVSETGLGFVW--GNPHAFNSKDENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLG 1765
            V +I+CSE   ++L+  G +     +S +++P          ML H   S         KI +LA       D QH LAL+  G++YSWG G  G+LGHGD      P LI        G  +  I+CG+++S+AV+  G  + W  GN        E+   P+    L+   +  + CG      L++ +  V+  G
Sbjct:  426 VTQIVCSEKVFLILSRSGAVYTQNYKSTTLAP----------MLIHGLSSR--------KIVKLAAH----PDGQHFLALSTSGEVYSWGCGDGGRLGHGDAY-LEEPALITTFSGKQTGKQVVQIACGSTYSAAVTADGELYTWGRGNYGRLGHSSEDVTTPMLVTALKGQKVVDVACGSGDAQTLAVTENQVWSWG 600

HSP 2 Score: 71.633 bits (174), Expect = 1.207e-11
Identity = 35/70 (50.00%), Postives = 49/70 (70.00%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGH-GDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            S+H +ALT  G+++SWG G  GKLGH     DK  P LIEAL+   IR+I+CG+SHS+A++ +G  + WG
Sbjct: 3002 SRHAMALTVDGKVFSWGEGDDGKLGHFSRNCDK--PRLIEALKTKRIRDIACGSSHSAAITSSGELYSWG 3069

HSP 3 Score: 68.5514 bits (166), Expect = 8.885e-11
Identity = 72/267 (26.97%), Postives = 116/267 (43.45%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETG-LGFVWGN---PHAFNSKDENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQH-------YPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIG---HGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVILGQNVIYSWSLTAETFSFIEEP 2125
            +I  +A G      S H  A+T  G+LYSWG G +G+LGHGD   +  P L++ L G+ +  ++CG+  +  ++ T  L F WG+           E C  P    RL    +  I CG  + F L++ K  V + G            F L H        P I+EGL      + +KI  +AV +   L + ++G +Y+ G   HG   G     +++    VQ +   K+  ++   +H V        +W+    T   + EP
Sbjct: 3045 RIRDIACG------SSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVIQVACGSRDAQTLALTDELVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECG--AQFSLALTKSGVVWTGK--------GDYFRLGHGTDVHVRKPQIVEGL------RGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHG-QQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSV--------AWTTVDVTTPSVHEP 3280

HSP 4 Score: 66.2402 bits (160), Expect = 5.087e-10
Identity = 30/69 (43.48%), Postives = 46/69 (66.67%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDM-LDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H LAL+  G++YSWG    GKLGHG+   D+  P +IE+LRG  + +I+ G +HS+ ++ +G  F WG
Sbjct: 3988 KHCLALSSEGEVYSWGEAEDGKLGHGNRPCDR--PRVIESLRGVEVVDIAAGGAHSACITASGELFTWG 4054

HSP 5 Score: 65.4698 bits (158), Expect = 9.228e-10
Identity = 35/122 (28.69%), Postives = 61/122 (50.00%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPVRLRQAIMSSIV---CGPHSTFFLSINKRNVYYLG 1765
            H   +T  G+L++WG G +G+LGHGD  D+  P L++AL+G+ + +++CG+  +  +  T    VW        K      + C  P+++       +V   CG  S F +++ K    Y G
Sbjct: 4040 HSACITASGELFTWGKGRYGRLGHGDSEDQLKPKLVDALQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECG--SQFSVALTKSGAVYTG 4159

HSP 6 Score: 57.3806 bits (137), Expect = 2.442e-7
Identity = 33/100 (33.00%), Postives = 57/100 (57.00%), Query Frame = 2 
Query: 1415 DSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG---NPHAFNSKDENCLFPVRLRQAIMSSIV 1705
            D+Q  LA+T++ Q++SWG G +GKLG G      +P L+E L+  +I  + CG+  S A+++ G  + WG   N    +  DE+  +P +L  ++   +V
Sbjct:  585 DAQ-TLAVTEN-QVWSWGDGDYGKLGRGGSDGCKTPKLVEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYP-KLLDSLQKKVV 681

HSP 7 Score: 56.225 bits (134), Expect = 5.065e-7
Identity = 36/114 (31.58%), Postives = 57/114 (50.00%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVR--------LRQAIMSSIVCGPHSTFFLS 1735
            SQ  +ALT+ GQ+Y+WG G   +LGHG       P L+++L+   + +I+ G++H  A+++ G    WG+       D   LFP +        L    +  I CGP  +F  S
Sbjct:  636 SQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSLQK-KVVDIAVGSTHCLALTDEGEVHSWGSNDKLQHFD--TLFPNKKQPKALPGLNSKHIVGISCGPGQSFAWS 746
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Medaka
Match: rccd1 (RCC1 domain containing 1 [Source:NCBI gene;Acc:101168618])

HSP 1 Score: 68.5514 bits (166), Expect = 2.467e-11
Identity = 34/88 (38.64%), Postives = 52/88 (59.09%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQ 1684
            +H++ LT  G +Y+WG GS G+LGHG +L +  P  +EAL G  + ++S G  HS  +S+ G  +VWG    +N   +  L   RLR+
Sbjct:  162 EHVILLTATGAVYTWGQGSHGQLGHGGLLPEEEPRTVEALWGMKMSSVSAGGWHSVCISDAGDLYVWG----WNESGQLGLPSQRLRK 245
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Medaka
Match: herc3 (HECT and RLD domain containing E3 ubiquitin protein ligase 3 [Source:NCBI gene;Acc:101155493])

HSP 1 Score: 68.1662 bits (165), Expect = 8.987e-11
Identity = 58/230 (25.22%), Postives = 95/230 (41.30%), Query Frame = 2 
Query: 1115 IYIWEHGRK----LETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRS---RSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN---PHAFNSKDENCLFPVRLRQAI---MSSIVCGPHSTFFLSINKRNVYYLG 1765
            +++W  G      LET +       L +  C   +HS+ +++C     I L+  GQ+ +    S       K E   +      S    P     + Q+  G        H  AL+  G ++ WG    G+LG  D  D+  P  I+ LR   +  ISCG  H++A++++G  F +G+       +    N L P R+ + +   +S I CG H T     +   VY  G
Sbjct:  104 VFVWGAGDGGQLGLETAETAVRIPRLLKKLC---DHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAGIP-----LAQITAG------GDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPSSGTVYAFG 319

HSP 2 Score: 61.6178 bits (148), Expect = 1.087e-8
Identity = 41/113 (36.28%), Postives = 54/113 (47.79%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAI-------MSSIVCGPHSTFFLS 1735
             QH L L Q G +Y+ G  S G+LGH      +SP L+ AL    I  +SCG +HS AV+E G  FVWG         E     VR+ + +       +S +VCG      LS
Sbjct:   42 GQHTLFLLQDGSVYTCGSNSCGQLGHDKA--GNSPELVGALDTQKITMVSCGRAHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRIPRLLKKLCDHSISQVVCGNQHCIALS 152
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Medaka
Match: herc3 (HECT and RLD domain containing E3 ubiquitin protein ligase 3 [Source:NCBI gene;Acc:101155493])

HSP 1 Score: 68.1662 bits (165), Expect = 9.078e-11
Identity = 58/230 (25.22%), Postives = 95/230 (41.30%), Query Frame = 2 
Query: 1115 IYIWEHGRK----LETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRS---RSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN---PHAFNSKDENCLFPVRLRQAI---MSSIVCGPHSTFFLSINKRNVYYLG 1765
            +++W  G      LET +       L +  C   +HS+ +++C     I L+  GQ+ +    S       K E   +      S    P     + Q+  G        H  AL+  G ++ WG    G+LG  D  D+  P  I+ LR   +  ISCG  H++A++++G  F +G+       +    N L P R+ + +   +S I CG H T     +   VY  G
Sbjct:  104 VFVWGAGDGGQLGLETAETAVRIPRLLKKLC---DHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAGIP-----LAQITAG------GDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPSSGTVYAFG 319

HSP 2 Score: 61.6178 bits (148), Expect = 1.014e-8
Identity = 41/113 (36.28%), Postives = 54/113 (47.79%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAI-------MSSIVCGPHSTFFLS 1735
             QH L L Q G +Y+ G  S G+LGH      +SP L+ AL    I  +SCG +HS AV+E G  FVWG         E     VR+ + +       +S +VCG      LS
Sbjct:   42 GQHTLFLLQDGSVYTCGSNSCGQLGHDKA--GNSPELVGALDTQKITMVSCGRAHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRIPRLLKKLCDHSISQVVCGNQHCIALS 152
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Medaka
Match: herc3 (HECT and RLD domain containing E3 ubiquitin protein ligase 3 [Source:NCBI gene;Acc:101155493])

HSP 1 Score: 68.1662 bits (165), Expect = 9.237e-11
Identity = 58/230 (25.22%), Postives = 95/230 (41.30%), Query Frame = 2 
Query: 1115 IYIWEHGRK----LETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRS---RSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN---PHAFNSKDENCLFPVRLRQAI---MSSIVCGPHSTFFLSINKRNVYYLG 1765
            +++W  G      LET +       L +  C   +HS+ +++C     I L+  GQ+ +    S       K E   +      S    P     + Q+  G        H  AL+  G ++ WG    G+LG  D  D+  P  I+ LR   +  ISCG  H++A++++G  F +G+       +    N L P R+ + +   +S I CG H T     +   VY  G
Sbjct:  104 VFVWGAGDGGQLGLETAETAVRIPRLLKKLC---DHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAGIP-----LAQITAG------GDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPSSGTVYAFG 319

HSP 2 Score: 61.6178 bits (148), Expect = 1.068e-8
Identity = 39/105 (37.14%), Postives = 52/105 (49.52%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAI-------MSSIVCG 1711
             QH L L Q G +Y+ G  S G+LGH      +SP L+ AL    I  +SCG +HS AV+E G  FVWG         E     VR+ + +       +S +VCG
Sbjct:   42 GQHTLFLLQDGSVYTCGSNSCGQLGHDKA--GNSPELVGALDTQKITMVSCGRAHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRIPRLLKKLCDHSISQVVCG 144
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Planmine SMEST
Match: SMESG000006057.1 (SMESG000006057.1)

HSP 1 Score: 3712.54 bits (9626), Expect = 0.000e+0
Identity = 1926/1944 (99.07%), Postives = 1926/1944 (99.07%), Query Frame = 2 
Query:  110 MNYDIFNYKKGCEVKTDHTENCIMNNDLPNKYINFSNQFSKSYHYENQEITKEISFNINHKSELFNVIITNTPFYNFIEHFKSDFIQDINKLKELEVIYKDGNSTCNDIVKSNNNGSKEFILIEKQQNQIIDVSISKILKVLLSTVKCHLIASNNEFNSDNDVFKIIEDSIKELPLLILSKVINESHESSITEIKKFIHEIIEANANYWSYKSAVEIWLLLFTRIGSLDNILEWFCLVIQQIDSENDVLIRTEILSSVFESLFNGEGQLNAEIKENMMDCLEIDILEQEFIGLTQAINFIFLGVLRAFKVHSKHRQGIHETKKLNNDTKNDPFKDIYIWEHGRKLETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVILGQNVIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNTSKYFEQILPNTLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSNNTLFIKLFQLEFSKISDLLIAVCQNLSNYTINVLQNKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMNSIIGCFKSYLLTAVKLQKINQWIKGRGVEINLLLSKSPISWILFDVLNYLNEQHNLDILPLLPHIERXXXXXXXXXXXXPKTFNNDTQEIQWPLYGFSAFPNTSNIVPEPXXXXXXXXXXXXXXXXVLGNIFRKQLTLPLSNENAEDKXXXXXXXXXXXXKYIITLPICQVNDAHRIFNCICKQISVQLISGYAKLSASYNDLLTFMKIGQGVQFCAWSDKNFMYFTGLQIYEIIIQLLSNKFLLIDFRNSIFVYYAMRKIMNIITKHATECFGINLSSADNEMTEVQSNSFRNCIDILNKKCNFLTSLLKDSMETCDLTTFPEESELIEALDLRKINVKLVSNCLSSATNFRASSNRIFDMYTAKLPEKKILKFLKENLDILGMFLVMNTHFKNDVVDETNTFLHHLSSKIFFKRRSLDRITXXXXXXXXXXXXXXXXXXXXFLQILNAMLISPPSLKNQIYDCHIEIMEKIFISLIDKFNNNFSNALLNESSTILSQRISIALFNFLSSYHSGFIPLVNILIDHNFINLIMRSGNDRLLISNEKWLIIEGNGDNNLPKVCNMIAWCIMENFILNISMCEDKITRERMILLEDQFLQSLRQIYCGFTNEKIYQIFDLYYLLKVINYFYNKSESFRNICQNEAWIKMLLEISTDLCHSEERSIFYFNYNLNIVAIKFLFSIISHRAKQGSGEFQDSSNISYLEIFQKFSEFFYNLITKSTKLDIIRITNNMTKRIEFYKHFGDELNSCENNDRFDWIFGNCNFDKQRSFFCNFKSSDKISITNADFSDSGVIVLNSENLFSGIWHITFDIECVKNSIDFNYGFLINPTKKWPKDYTSIKKLVKQCSSMSISCRSATSYRLSCVIDIDQSFLCFSNSNNRIQTFTNSNGVFRFFISSSMNFHGSFEIQMISVKQLRLSEMYDDVEFYNNTQISPDYYLVLKHLYVEFNNFFAVIPDIYLYEIVGVLLEKSIYINQFDLYFDKNVRYFLFLNRKYY 5941
            MNYDIFNYKKGCEVKTDHTENCIMNNDLPNKYINFSNQFSKSYHYENQEITKEISFNINHKSELFNVIITNTPFYNFIEHFKSDFIQDINKLKELEVIYKDGNSTCNDIVKSNNNGSKEFILIEKQQNQIIDVSISKILKVLLSTVKCHLIASNNEFNSDNDVFKIIEDSIKELPLLILSKVINESHESSITEIKKFIHEIIEANANYWSYKSAVEIWLLLFTRIGSLDNILEWFCLVIQQIDSENDVLIRTEILSSVFESLFNGEGQLNAEIKENMMDCLEIDILEQEFIGLTQAINFIFLGVLRAFKVHSKHRQGIHETKKLNNDTKNDPFKDIYIWEHGRKLETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIGHGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVILGQNVIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNTSKYFEQILPNTLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSNNTLFIKLFQLEFSKISDLLIAVCQNLSNYTINVLQNKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMNSIIGCFKSYLLTAVKLQKINQWIKGRGVEINLLLSKSPISWILFDVLNYLNEQHNLDILPLLPHIERLILILDSINIILPKTFNNDTQEIQWPLYGFSAFPNTSNIVPEPGLTWLWLLDLQRLTGLVLGNIFRKQLTLPLSNENAEDKSLFTTLLETSLFKYIITLPICQVNDAHR                YAKLSASYNDLLTFMKIGQGVQFCAWSDKNFMYFTGLQIYEIIIQLLSNKFLLIDFRNSIFVYYAMRKIMNIITKHATECFGINLSSADNEMTEVQSNSFRNCIDILNKKCNFLTSLLKDSMETCDLTTFPEESELIEALDLRKINVKLVSNCLSSATNFRASSNRIFDMYTAKLPEKKILKFLKENLDILGMFLVMNTHFKNDVVDETNTFLHHLSSKIFFKRRSLDRITKVFLSFSKLLDSSKLSVNSVFLQILNAMLISPPSLKNQIYDCHIEIMEKIFISLIDKFNNNFSNALLNESSTILSQRISIALFNFLSSYHSGFIPLVNILIDHNFINLIMRSGNDRLLISNEKWLIIEGNGDNNLPKVCNMIAWCIMENFILNISMCEDKITRERMILLEDQFLQSLRQIYCGFTNEKIYQIFDLYYLLKVINYFYNKSESFRNICQNEAWIKMLLEISTDLCHSEERSIFYFNYNLNIVAIKFLFSIISHRAKQGSGEFQDSSNISYLEIFQKFSEFFYNLITKSTKLDIIRITNNMTKRIEFYKHFGDELNSCENNDRFDWIFGNCNFDKQRSFFCNFKSSDKISITNADFSDSGVIVLNSENLFSGIWHITFDIECVKNSIDFNYGFLINPTKKWPKDYTSIKKLVKQCSSMSISCRSATSYRLSCVIDIDQSFLCFSNSNNRIQTFTNSNGVFRFFISSSMNFHGSFEIQMISVKQLRLSEMYDDVEFYNNTQISPDYYLVLKHLYVEFNNFFAVIPDIYLYEIVGVLLEKSIYINQFDLYFDKNVRYFLFLNR  Y
Sbjct:    1 MNYDIFNYKKGCEVKTDHTENCIMNNDLPNKYINFSNQFSKSYHYENQEITKEISFNINHKSELFNVIITNTPFYNFIEHFKSDFIQDINKLKELEVIYKDGNSTCNDIVKSNNNGSKEFILIEKQQNQIIDVSISKILKVLLSTVKCHLIASNNEFNSDNDVFKIIEDSIKELPLLILSKVINESHESSITEIKKFIHEIIEANANYWSYKSAVEIWLLLFTRIGSLDNILEWFCLVIQQIDSENDVLIRTEILSSVFESLFNGEGQLNAEIKENMMDCLEIDILEQEFIGLTQAINFIFLGVLRAFKVHSKHRQGIHETKKLNNDTKNDPFKDIYIWEHGRKLETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIGHGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVILGQNVIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNTSKYFEQILPNTLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSNNTLFIKLFQLEFSKISDLLIAVCQNLSNYTINVLQNKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMNSIIGCFKSYLLTAVKLQKINQWIKGRGVEINLLLSKSPISWILFDVLNYLNEQHNLDILPLLPHIERLILILDSINIILPKTFNNDTQEIQWPLYGFSAFPNTSNIVPEPGLTWLWLLDLQRLTGLVLGNIFRKQLTLPLSNENAEDKSLFTTLLETSLFKYIITLPICQVNDAHR----------------YAKLSASYNDLLTFMKIGQGVQFCAWSDKNFMYFTGLQIYEIIIQLLSNKFLLIDFRNSIFVYYAMRKIMNIITKHATECFGINLSSADNEMTEVQSNSFRNCIDILNKKCNFLTSLLKDSMETCDLTTFPEESELIEALDLRKINVKLVSNCLSSATNFRASSNRIFDMYTAKLPEKKILKFLKENLDILGMFLVMNTHFKNDVVDETNTFLHHLSSKIFFKRRSLDRITKVFLSFSKLLDSSKLSVNSVFLQILNAMLISPPSLKNQIYDCHIEIMEKIFISLIDKFNNNFSNALLNESSTILSQRISIALFNFLSSYHSGFIPLVNILIDHNFINLIMRSGNDRLLISNEKWLIIEGNGDNNLPKVCNMIAWCIMENFILNISMCEDKITRERMILLEDQFLQSLRQIYCGFTNEKIYQIFDLYYLLKVINYFYNKSESFRNICQNEAWIKMLLEISTDLCHSEERSIFYFNYNLNIVAIKFLFSIISHRAKQGSGEFQDSSNISYLEIFQKFSEFFYNLITKSTKLDIIRITNNMTKRIEFYKHFGDELNSCENNDRFDWIFGNCNFDKQRSFFCNFKSSDKISITNADFSDSGVIVLNSENLFSGIWHITFDIECVKNSIDFNYGFLINPTKKWPKDYTSIKKLVKQCSSMSISCRSATSYRLSCVIDIDQSFLCFSNSNNRIQTFTNSNGVFRFFISSSMNFHGSFEIQMISVKQLRLSEMYDDVEFYNNTQISPDYYLVLKHLYVEFNNFFAVIPDIYLYEIVGVLLEKSIYINQFDLYFDKNVRYFLFLNRDSY 1928

HSP 2 Score: 121.324 bits (303), Expect = 6.891e-27
Identity = 58/64 (90.62%), Postives = 60/64 (93.75%), Query Frame = 2 
Query: 6221 KYYLE*PGDSYCSSKIGTLDPVSVTKSTVFEKFGATLKDGDLGMAKKVMFWRKFAIDLSLKKNC 6412
            +Y+L    DSYCSSKIGTLDPVSVTKSTVFEKFGATLKDGDLGMAKKVMFWRKFAIDLSLKKNC
Sbjct: 1918 RYFLFLNRDSYCSSKIGTLDPVSVTKSTVFEKFGATLKDGDLGMAKKVMFWRKFAIDLSLKKNC 1981

HSP 3 Score: 70.8626 bits (172), Expect = 1.382e-11
Identity = 47/141 (33.33%), Postives = 66/141 (46.81%), Query Frame = 2 
Query: 1403 PILND------------SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG---NPHAFNSKDENCLFPVRL-----RQAIMSSIVCGPHSTFFLSINKRNVYYLG 1765
            P+LND              HI+A+T  G+++SWG GS GKLGHG       P  IEALRG       CG  HS+ V+ +G  +++G   N    N     C  P RL      +  +  + CG + T  LS + + +Y  G
Sbjct: 3567 PVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTP-RLVDFTDGEPKIGFVSCGMNHTLALSTDGQKLYAFG 3706

HSP 4 Score: 66.6254 bits (161), Expect = 3.056e-10
Identity = 52/180 (28.89%), Postives = 87/180 (48.33%), Query Frame = 2 
Query: 1340 CWSP--INFPDVKCKIEQLAVGWPILNDSQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNS---------KDENCLFPVRLRQAIMSSI----VCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSII 1831
            C +P  ++F D + KI  ++ G        H LAL+  GQ LY++G G +GKLG GD+ D+ SPTL++  +   +  + CG S S+A++E G  + WG+     +          DE+ L    L  +++       +C  + T F   N  ++Y  GS  + N L        +YP ++
Sbjct: 3667 CDTPRLVDFTDGEPKIGFVSCG------MNHTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSPTLVD-FQKKKLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSN-ANNLLRLGGKAHAYYPELV 3838
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Planmine SMEST
Match: SMESG000006057.1 (SMESG000006057.1)

HSP 1 Score: 3712.15 bits (9625), Expect = 0.000e+0
Identity = 1926/1944 (99.07%), Postives = 1926/1944 (99.07%), Query Frame = 2 
Query:  110 MNYDIFNYKKGCEVKTDHTENCIMNNDLPNKYINFSNQFSKSYHYENQEITKEISFNINHKSELFNVIITNTPFYNFIEHFKSDFIQDINKLKELEVIYKDGNSTCNDIVKSNNNGSKEFILIEKQQNQIIDVSISKILKVLLSTVKCHLIASNNEFNSDNDVFKIIEDSIKELPLLILSKVINESHESSITEIKKFIHEIIEANANYWSYKSAVEIWLLLFTRIGSLDNILEWFCLVIQQIDSENDVLIRTEILSSVFESLFNGEGQLNAEIKENMMDCLEIDILEQEFIGLTQAINFIFLGVLRAFKVHSKHRQGIHETKKLNNDTKNDPFKDIYIWEHGRKLETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVILGQNVIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNTSKYFEQILPNTLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSNNTLFIKLFQLEFSKISDLLIAVCQNLSNYTINVLQNKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMNSIIGCFKSYLLTAVKLQKINQWIKGRGVEINLLLSKSPISWILFDVLNYLNEQHNLDILPLLPHIERXXXXXXXXXXXXPKTFNNDTQEIQWPLYGFSAFPNTSNIVPEPXXXXXXXXXXXXXXXXVLGNIFRKQLTLPLSNENAEDKXXXXXXXXXXXXKYIITLPICQVNDAHRIFNCICKQISVQLISGYAKLSASYNDLLTFMKIGQGVQFCAWSDKNFMYFTGLQIYEIIIQLLSNKFLLIDFRNSIFVYYAMRKIMNIITKHATECFGINLSSADNEMTEVQSNSFRNCIDILNKKCNFLTSLLKDSMETCDLTTFPEESELIEALDLRKINVKLVSNCLSSATNFRASSNRIFDMYTAKLPEKKILKFLKENLDILGMFLVMNTHFKNDVVDETNTFLHHLSSKIFFKRRSLDRITXXXXXXXXXXXXXXXXXXXXFLQILNAMLISPPSLKNQIYDCHIEIMEKIFISLIDKFNNNFSNALLNESSTILSQRISIALFNFLSSYHSGFIPLVNILIDHNFINLIMRSGNDRLLISNEKWLIIEGNGDNNLPKVCNMIAWCIMENFILNISMCEDKITRERMILLEDQFLQSLRQIYCGFTNEKIYQIFDLYYLLKVINYFYNKSESFRNICQNEAWIKMLLEISTDLCHSEERSIFYFNYNLNIVAIKFLFSIISHRAKQGSGEFQDSSNISYLEIFQKFSEFFYNLITKSTKLDIIRITNNMTKRIEFYKHFGDELNSCENNDRFDWIFGNCNFDKQRSFFCNFKSSDKISITNADFSDSGVIVLNSENLFSGIWHITFDIECVKNSIDFNYGFLINPTKKWPKDYTSIKKLVKQCSSMSISCRSATSYRLSCVIDIDQSFLCFSNSNNRIQTFTNSNGVFRFFISSSMNFHGSFEIQMISVKQLRLSEMYDDVEFYNNTQISPDYYLVLKHLYVEFNNFFAVIPDIYLYEIVGVLLEKSIYINQFDLYFDKNVRYFLFLNRKYY 5941
            MNYDIFNYKKGCEVKTDHTENCIMNNDLPNKYINFSNQFSKSYHYENQEITKEISFNINHKSELFNVIITNTPFYNFIEHFKSDFIQDINKLKELEVIYKDGNSTCNDIVKSNNNGSKEFILIEKQQNQIIDVSISKILKVLLSTVKCHLIASNNEFNSDNDVFKIIEDSIKELPLLILSKVINESHESSITEIKKFIHEIIEANANYWSYKSAVEIWLLLFTRIGSLDNILEWFCLVIQQIDSENDVLIRTEILSSVFESLFNGEGQLNAEIKENMMDCLEIDILEQEFIGLTQAINFIFLGVLRAFKVHSKHRQGIHETKKLNNDTKNDPFKDIYIWEHGRKLETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIGHGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVILGQNVIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNTSKYFEQILPNTLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSNNTLFIKLFQLEFSKISDLLIAVCQNLSNYTINVLQNKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMNSIIGCFKSYLLTAVKLQKINQWIKGRGVEINLLLSKSPISWILFDVLNYLNEQHNLDILPLLPHIERLILILDSINIILPKTFNNDTQEIQWPLYGFSAFPNTSNIVPEPGLTWLWLLDLQRLTGLVLGNIFRKQLTLPLSNENAEDKSLFTTLLETSLFKYIITLPICQVNDAHR                YAKLSASYNDLLTFMKIGQGVQFCAWSDKNFMYFTGLQIYEIIIQLLSNKFLLIDFRNSIFVYYAMRKIMNIITKHATECFGINLSSADNEMTEVQSNSFRNCIDILNKKCNFLTSLLKDSMETCDLTTFPEESELIEALDLRKINVKLVSNCLSSATNFRASSNRIFDMYTAKLPEKKILKFLKENLDILGMFLVMNTHFKNDVVDETNTFLHHLSSKIFFKRRSLDRITKVFLSFSKLLDSSKLSVNSVFLQILNAMLISPPSLKNQIYDCHIEIMEKIFISLIDKFNNNFSNALLNESSTILSQRISIALFNFLSSYHSGFIPLVNILIDHNFINLIMRSGNDRLLISNEKWLIIEGNGDNNLPKVCNMIAWCIMENFILNISMCEDKITRERMILLEDQFLQSLRQIYCGFTNEKIYQIFDLYYLLKVINYFYNKSESFRNICQNEAWIKMLLEISTDLCHSEERSIFYFNYNLNIVAIKFLFSIISHRAKQGSGEFQDSSNISYLEIFQKFSEFFYNLITKSTKLDIIRITNNMTKRIEFYKHFGDELNSCENNDRFDWIFGNCNFDKQRSFFCNFKSSDKISITNADFSDSGVIVLNSENLFSGIWHITFDIECVKNSIDFNYGFLINPTKKWPKDYTSIKKLVKQCSSMSISCRSATSYRLSCVIDIDQSFLCFSNSNNRIQTFTNSNGVFRFFISSSMNFHGSFEIQMISVKQLRLSEMYDDVEFYNNTQISPDYYLVLKHLYVEFNNFFAVIPDIYLYEIVGVLLEKSIYINQFDLYFDKNVRYFLFLNR  Y
Sbjct:    1 MNYDIFNYKKGCEVKTDHTENCIMNNDLPNKYINFSNQFSKSYHYENQEITKEISFNINHKSELFNVIITNTPFYNFIEHFKSDFIQDINKLKELEVIYKDGNSTCNDIVKSNNNGSKEFILIEKQQNQIIDVSISKILKVLLSTVKCHLIASNNEFNSDNDVFKIIEDSIKELPLLILSKVINESHESSITEIKKFIHEIIEANANYWSYKSAVEIWLLLFTRIGSLDNILEWFCLVIQQIDSENDVLIRTEILSSVFESLFNGEGQLNAEIKENMMDCLEIDILEQEFIGLTQAINFIFLGVLRAFKVHSKHRQGIHETKKLNNDTKNDPFKDIYIWEHGRKLETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIGHGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVILGQNVIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNTSKYFEQILPNTLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSNNTLFIKLFQLEFSKISDLLIAVCQNLSNYTINVLQNKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMNSIIGCFKSYLLTAVKLQKINQWIKGRGVEINLLLSKSPISWILFDVLNYLNEQHNLDILPLLPHIERLILILDSINIILPKTFNNDTQEIQWPLYGFSAFPNTSNIVPEPGLTWLWLLDLQRLTGLVLGNIFRKQLTLPLSNENAEDKSLFTTLLETSLFKYIITLPICQVNDAHR----------------YAKLSASYNDLLTFMKIGQGVQFCAWSDKNFMYFTGLQIYEIIIQLLSNKFLLIDFRNSIFVYYAMRKIMNIITKHATECFGINLSSADNEMTEVQSNSFRNCIDILNKKCNFLTSLLKDSMETCDLTTFPEESELIEALDLRKINVKLVSNCLSSATNFRASSNRIFDMYTAKLPEKKILKFLKENLDILGMFLVMNTHFKNDVVDETNTFLHHLSSKIFFKRRSLDRITKVFLSFSKLLDSSKLSVNSVFLQILNAMLISPPSLKNQIYDCHIEIMEKIFISLIDKFNNNFSNALLNESSTILSQRISIALFNFLSSYHSGFIPLVNILIDHNFINLIMRSGNDRLLISNEKWLIIEGNGDNNLPKVCNMIAWCIMENFILNISMCEDKITRERMILLEDQFLQSLRQIYCGFTNEKIYQIFDLYYLLKVINYFYNKSESFRNICQNEAWIKMLLEISTDLCHSEERSIFYFNYNLNIVAIKFLFSIISHRAKQGSGEFQDSSNISYLEIFQKFSEFFYNLITKSTKLDIIRITNNMTKRIEFYKHFGDELNSCENNDRFDWIFGNCNFDKQRSFFCNFKSSDKISITNADFSDSGVIVLNSENLFSGIWHITFDIECVKNSIDFNYGFLINPTKKWPKDYTSIKKLVKQCSSMSISCRSATSYRLSCVIDIDQSFLCFSNSNNRIQTFTNSNGVFRFFISSSMNFHGSFEIQMISVKQLRLSEMYDDVEFYNNTQISPDYYLVLKHLYVEFNNFFAVIPDIYLYEIVGVLLEKSIYINQFDLYFDKNVRYFLFLNRDSY 1928

HSP 2 Score: 121.324 bits (303), Expect = 6.944e-27
Identity = 58/64 (90.62%), Postives = 60/64 (93.75%), Query Frame = 2 
Query: 6221 KYYLE*PGDSYCSSKIGTLDPVSVTKSTVFEKFGATLKDGDLGMAKKVMFWRKFAIDLSLKKNC 6412
            +Y+L    DSYCSSKIGTLDPVSVTKSTVFEKFGATLKDGDLGMAKKVMFWRKFAIDLSLKKNC
Sbjct: 1918 RYFLFLNRDSYCSSKIGTLDPVSVTKSTVFEKFGATLKDGDLGMAKKVMFWRKFAIDLSLKKNC 1981

HSP 3 Score: 70.8626 bits (172), Expect = 1.325e-11
Identity = 47/141 (33.33%), Postives = 66/141 (46.81%), Query Frame = 2 
Query: 1403 PILND------------SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG---NPHAFNSKDENCLFPVRL-----RQAIMSSIVCGPHSTFFLSINKRNVYYLG 1765
            P+LND              HI+A+T  G+++SWG GS GKLGHG       P  IEALRG       CG  HS+ V+ +G  +++G   N    N     C  P RL      +  +  + CG + T  LS + + +Y  G
Sbjct: 3543 PVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTP-RLVDFTDGEPKIGFVSCGMNHTLALSTDGQKLYAFG 3682

HSP 4 Score: 66.6254 bits (161), Expect = 2.930e-10
Identity = 52/180 (28.89%), Postives = 87/180 (48.33%), Query Frame = 2 
Query: 1340 CWSP--INFPDVKCKIEQLAVGWPILNDSQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNS---------KDENCLFPVRLRQAIMSSI----VCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSII 1831
            C +P  ++F D + KI  ++ G        H LAL+  GQ LY++G G +GKLG GD+ D+ SPTL++  +   +  + CG S S+A++E G  + WG+     +          DE+ L    L  +++       +C  + T F   N  ++Y  GS  + N L        +YP ++
Sbjct: 3643 CDTPRLVDFTDGEPKIGFVSCG------MNHTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSPTLVD-FQKKKLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSN-ANNLLRLGGKAHAYYPELV 3814
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Planmine SMEST
Match: SMESG000006057.1 (SMESG000006057.1)

HSP 1 Score: 3694.05 bits (9578), Expect = 0.000e+0
Identity = 1916/1933 (99.12%), Postives = 1917/1933 (99.17%), Query Frame = 2 
Query:  110 MNYDIFNYKKGCEVKTDHTENCIMNNDLPNKYINFSNQFSKSYHYENQEITKEISFNINHKSELFNVIITNTPFYNFIEHFKSDFIQDINKLKELEVIYKDGNSTCNDIVKSNNNGSKEFILIEKQQNQIIDVSISKILKVLLSTVKCHLIASNNEFNSDNDVFKIIEDSIKELPLLILSKVINESHESSITEIKKFIHEIIEANANYWSYKSAVEIWLLLFTRIGSLDNILEWFCLVIQQIDSENDVLIRTEILSSVFESLFNGEGQLNAEIKENMMDCLEIDILEQEFIGLTQAINFIFLGVLRAFKVHSKHRQGIHETKKLNNDTKNDPFKDIYIWEHGRKLETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVILGQNVIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNTSKYFEQILPNTLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSNNTLFIKLFQLEFSKISDLLIAVCQNLSNYTINVLQNKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMNSIIGCFKSYLLTAVKLQKINQWIKGRGVEINLLLSKSPISWILFDVLNYLNEQHNLDILPLLPHIERXXXXXXXXXXXXPKTFNNDTQEIQWPLYGFSAFPNTSNIVPEPXXXXXXXXXXXXXXXXVLGNIFRKQLTLPLSNENAEDKXXXXXXXXXXXXKYIITLPICQVNDAHRIFNCICKQISVQLISGYAKLSASYNDLLTFMKIGQGVQFCAWSDKNFMYFTGLQIYEIIIQLLSNKFLLIDFRNSIFVYYAMRKIMNIITKHATECFGINLSSADNEMTEVQSNSFRNCIDILNKKCNFLTSLLKDSMETCDLTTFPEESELIEALDLRKINVKLVSNCLSSATNFRASSNRIFDMYTAKLPEKKILKFLKENLDILGMFLVMNTHFKNDVVDETNTFLHHLSSKIFFKRRSLDRITXXXXXXXXXXXXXXXXXXXXFLQILNAMLISPPSLKNQIYDCHIEIMEKIFISLIDKFNNNFSNALLNESSTILSQRISIALFNFLSSYHSGFIPLVNILIDHNFINLIMRSGNDRLLISNEKWLIIEGNGDNNLPKVCNMIAWCIMENFILNISMCEDKITRERMILLEDQFLQSLRQIYCGFTNEKIYQIFDLYYLLKVINYFYNKSESFRNICQNEAWIKMLLEISTDLCHSEERSIFYFNYNLNIVAIKFLFSIISHRAKQGSGEFQDSSNISYLEIFQKFSEFFYNLITKSTKLDIIRITNNMTKRIEFYKHFGDELNSCENNDRFDWIFGNCNFDKQRSFFCNFKSSDKISITNADFSDSGVIVLNSENLFSGIWHITFDIECVKNSIDFNYGFLINPTKKWPKDYTSIKKLVKQCSSMSISCRSATSYRLSCVIDIDQSFLCFSNSNNRIQTFTNSNGVFRFFISSSMNFHGSFEIQMISVKQLRLSEMYDDVEFYNNTQISPDYYLVLKHLYVEFNNFFAVIPDIYLYEIVGVLLEKSIYINQFDLYFDKNV 5908
            MNYDIFNYKKGCEVKTDHTENCIMNNDLPNKYINFSNQFSKSYHYENQEITKEISFNINHKSELFNVIITNTPFYNFIEHFKSDFIQDINKLKELEVIYKDGNSTCNDIVKSNNNGSKEFILIEKQQNQIIDVSISKILKVLLSTVKCHLIASNNEFNSDNDVFKIIEDSIKELPLLILSKVINESHESSITEIKKFIHEIIEANANYWSYKSAVEIWLLLFTRIGSLDNILEWFCLVIQQIDSENDVLIRTEILSSVFESLFNGEGQLNAEIKENMMDCLEIDILEQEFIGLTQAINFIFLGVLRAFKVHSKHRQGIHETKKLNNDTKNDPFKDIYIWEHGRKLETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIGHGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVILGQNVIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNTSKYFEQILPNTLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSNNTLFIKLFQLEFSKISDLLIAVCQNLSNYTINVLQNKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMNSIIGCFKSYLLTAVKLQKINQWIKGRGVEINLLLSKSPISWILFDVLNYLNEQHNLDILPLLPHIERLILILDSINIILPKTFNNDTQEIQWPLYGFSAFPNTSNIVPEPGLTWLWLLDLQRLTGLVLGNIFRKQLTLPLSNENAEDKSLFTTLLETSLFKYIITLPICQVNDAHR                YAKLSASYNDLLTFMKIGQGVQFCAWSDKNFMYFTGLQIYEIIIQLLSNKFLLIDFRNSIFVYYAMRKIMNIITKHATECFGINLSSADNEMTEVQSNSFRNCIDILNKKCNFLTSLLKDSMETCDLTTFPEESELIEALDLRKINVKLVSNCLSSATNFRASSNRIFDMYTAKLPEKKILKFLKENLDILGMFLVMNTHFKNDVVDETNTFLHHLSSKIFFKRRSLDRITKVFLSFSKLLDSSKLSVNSVFLQILNAMLISPPSLKNQIYDCHIEIMEKIFISLIDKFNNNFSNALLNESSTILSQRISIALFNFLSSYHSGFIPLVNILIDHNFINLIMRSGNDRLLISNEKWLIIEGNGDNNLPKVCNMIAWCIMENFILNISMCEDKITRERMILLEDQFLQSLRQIYCGFTNEKIYQIFDLYYLLKVINYFYNKSESFRNICQNEAWIKMLLEISTDLCHSEERSIFYFNYNLNIVAIKFLFSIISHRAKQGSGEFQDSSNISYLEIFQKFSEFFYNLITKSTKLDIIRITNNMTKRIEFYKHFGDELNSCENNDRFDWIFGNCNFDKQRSFFCNFKSSDKISITNADFSDSGVIVLNSENLFSGIWHITFDIECVKNSIDFNYGFLINPTKKWPKDYTSIKKLVKQCSSMSISCRSATSYRLSCVIDIDQSFLCFSNSNNRIQTFTNSNGVFRFFISSSMNFHGSFEIQMISVKQLRLSEMYDDVEFYNNTQISPDYYLVLKHLYVEFNNFFAVIPDIYLYEIVGVLLEKSIYINQFDLYFDKN+
Sbjct:    1 MNYDIFNYKKGCEVKTDHTENCIMNNDLPNKYINFSNQFSKSYHYENQEITKEISFNINHKSELFNVIITNTPFYNFIEHFKSDFIQDINKLKELEVIYKDGNSTCNDIVKSNNNGSKEFILIEKQQNQIIDVSISKILKVLLSTVKCHLIASNNEFNSDNDVFKIIEDSIKELPLLILSKVINESHESSITEIKKFIHEIIEANANYWSYKSAVEIWLLLFTRIGSLDNILEWFCLVIQQIDSENDVLIRTEILSSVFESLFNGEGQLNAEIKENMMDCLEIDILEQEFIGLTQAINFIFLGVLRAFKVHSKHRQGIHETKKLNNDTKNDPFKDIYIWEHGRKLETLKAPYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKKHENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIGHGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVILGQNVIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNSEGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNTSKYFEQILPNTLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKNKKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILSLNDTSNNTLFIKLFQLEFSKISDLLIAVCQNLSNYTINVLQNKMNFNRSENLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMNSIIGCFKSYLLTAVKLQKINQWIKGRGVEINLLLSKSPISWILFDVLNYLNEQHNLDILPLLPHIERLILILDSINIILPKTFNNDTQEIQWPLYGFSAFPNTSNIVPEPGLTWLWLLDLQRLTGLVLGNIFRKQLTLPLSNENAEDKSLFTTLLETSLFKYIITLPICQVNDAHR----------------YAKLSASYNDLLTFMKIGQGVQFCAWSDKNFMYFTGLQIYEIIIQLLSNKFLLIDFRNSIFVYYAMRKIMNIITKHATECFGINLSSADNEMTEVQSNSFRNCIDILNKKCNFLTSLLKDSMETCDLTTFPEESELIEALDLRKINVKLVSNCLSSATNFRASSNRIFDMYTAKLPEKKILKFLKENLDILGMFLVMNTHFKNDVVDETNTFLHHLSSKIFFKRRSLDRITKVFLSFSKLLDSSKLSVNSVFLQILNAMLISPPSLKNQIYDCHIEIMEKIFISLIDKFNNNFSNALLNESSTILSQRISIALFNFLSSYHSGFIPLVNILIDHNFINLIMRSGNDRLLISNEKWLIIEGNGDNNLPKVCNMIAWCIMENFILNISMCEDKITRERMILLEDQFLQSLRQIYCGFTNEKIYQIFDLYYLLKVINYFYNKSESFRNICQNEAWIKMLLEISTDLCHSEERSIFYFNYNLNIVAIKFLFSIISHRAKQGSGEFQDSSNISYLEIFQKFSEFFYNLITKSTKLDIIRITNNMTKRIEFYKHFGDELNSCENNDRFDWIFGNCNFDKQRSFFCNFKSSDKISITNADFSDSGVIVLNSENLFSGIWHITFDIECVKNSIDFNYGFLINPTKKWPKDYTSIKKLVKQCSSMSISCRSATSYRLSCVIDIDQSFLCFSNSNNRIQTFTNSNGVFRFFISSSMNFHGSFEIQMISVKQLRLSEMYDDVEFYNNTQISPDYYLVLKHLYVEFNNFFAVIPDIYLYEIVGVLLEKSIYINQFDLYFDKNI 1917

HSP 2 Score: 71.2478 bits (173), Expect = 1.214e-11
Identity = 47/141 (33.33%), Postives = 66/141 (46.81%), Query Frame = 2 
Query: 1403 PILND------------SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG---NPHAFNSKDENCLFPVRL-----RQAIMSSIVCGPHSTFFLSINKRNVYYLG 1765
            P+LND              HI+A+T  G+++SWG GS GKLGHG       P  IEALRG       CG  HS+ V+ +G  +++G   N    N     C  P RL      +  +  + CG + T  LS + + +Y  G
Sbjct: 3350 PVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTP-RLVDFTDGEPKIGFVSCGMNHTLALSTDGQKLYAFG 3489

HSP 3 Score: 66.6254 bits (161), Expect = 2.708e-10
Identity = 52/180 (28.89%), Postives = 87/180 (48.33%), Query Frame = 2 
Query: 1340 CWSP--INFPDVKCKIEQLAVGWPILNDSQHILALTQHGQ-LYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNS---------KDENCLFPVRLRQAIMSSI----VCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSII 1831
            C +P  ++F D + KI  ++ G        H LAL+  GQ LY++G G +GKLG GD+ D+ SPTL++  +   +  + CG S S+A++E G  + WG+     +          DE+ L    L  +++       +C  + T F   N  ++Y  GS  + N L        +YP ++
Sbjct: 3450 CDTPRLVDFTDGEPKIGFVSCGM------NHTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSPTLVD-FQKKKLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSN-ANNLLRLGGKAHAYYPELV 3621
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Planmine SMEST
Match: SMESG000054104.1 (SMESG000054104.1)

HSP 1 Score: 70.8626 bits (172), Expect = 1.559e-11
Identity = 40/131 (30.53%), Postives = 64/131 (48.85%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGNPHAFNSK-----DENCLFPVRLRQAIMSSIV---CGPHSTFFLSIN-------KRNVYYLG 1765
            S H  A+   G LY+WG G +G+LGHGD   +  P L+++LR Y +  ++CG+  +  ++ T    VW        K        CL P ++    +S+++   CG  S+F L+ N       K + Y LG
Sbjct: 3276 SSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWGDGDFGKLGRGGSSGCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLG 3406

HSP 2 Score: 68.5514 bits (166), Expect = 8.484e-11
Identity = 57/214 (26.64%), Postives = 94/214 (43.93%), Query Frame = 2 
Query: 1202 ENHSVREIICSENEIIVLNNLGQIRSRSISPPS-----TKKHENIVMLFH--------QCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRG--YNIRNISCGASHSSAVSETGLGFVWGNPHA-----FNSKDENCLFPVRLRQA-----IMSSIVCGPHSTFFLSINKRNVYYLGS 1768
            E   +++I+CS  +  VL++ G +   + S        T KH  I   F         + WS     DV   I            S H+LA+T+ GQ+YSWG  + GKLG GD  D+  PT+I+        ++ ++CG  HS  ++++G  +  G  H       + KD +   P+R+  +     ++  I    H +  LS N   ++  GS
Sbjct:  454 EKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIY-----------SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRH--LPIRITASDLIGVLVKQIAVDGHQSMCLS-NDGAIFTWGS 653

HSP 3 Score: 67.781 bits (164), Expect = 1.258e-10
Identity = 28/76 (36.84%), Postives = 48/76 (63.16%), Query Frame = 2 
Query: 1367 VKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAV 1594
            VK +I  +A G        H  A+++ G+LY+WG G +G+LGHG+  D+  P ++EALRGY++  ++CG+  +  +
Sbjct: 4271 VKAEIIDIAAG------GSHSAAISRSGELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTL 4340

HSP 4 Score: 66.6254 bits (161), Expect = 2.815e-10
Identity = 27/68 (39.71%), Postives = 44/68 (64.71%), Query Frame = 2 
Query: 1421 QHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            +H +ALT++G+ +SWG G  GKLGH   L  + P  I+  +G  + +++CG+SHS+A+   G  + WG
Sbjct: 3225 RHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWG 3292

HSP 5 Score: 63.929 bits (154), Expect = 1.723e-9
Identity = 35/88 (39.77%), Postives = 50/88 (56.82%), Query Frame = 2 
Query: 1349 PINFPDVK-CKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGL 1609
            P+   D+K  KI  LAVG      + H LA+T  GQ+YSWG    G+ G+G +     PTL+ AL    I +++CG+SHS A + + L
Sbjct: 3416 PMQIEDLKKTKIVHLAVG------ALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDL 3497

HSP 6 Score: 60.4622 bits (145), Expect = 2.188e-8
Identity = 34/99 (34.34%), Postives = 56/99 (56.57%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKH--SPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG-NPHAFNSKDENCLFPVRLRQAIMSSIV 1705
            +Q   ALT++GQ+++WG G + +LGHG   DKH   P  IE L+   I +++ GA H  AV++ G  + WG N H    +  N      +R  ++S+++
Sbjct: 3382 AQSSFALTENGQVWTWGKGDYYRLGHG--TDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHG---QQGNGTVTYNMRPTLVSALM 3475

HSP 7 Score: 57.3806 bits (137), Expect = 1.842e-7
Identity = 34/83 (40.96%), Postives = 44/83 (53.01%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 1624
            K+ Q+A G     D+Q  LALT    ++SWG G FGKLG G       P  IE +   N+  I CGA  S A++E G  + WG
Sbjct: 3320 KVVQVACG---SRDAQ-TLALTSDFTVWSWGDGDFGKLGRGGSSGCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWG 3398

HSP 8 Score: 57.3806 bits (137), Expect = 2.054e-7
Identity = 62/260 (23.85%), Postives = 112/260 (43.08%), Query Frame = 2 
Query: 1382 EQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDML----DKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN---PHAFNSKDENCLFPV---RLRQAIMSSIVCGPHSTFFLSINKR-----------NVYYLGSQCSENELFTKDFILQHYP---SIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVILGQN-VIYSW 2086
            E++ V   + +  +H LAL  +G +Y+WG     KLG    +    D  +PTL+++L    I +I+ G SHS+A+S +G  + WG        +   ++  FP     LR   +  + CG      L I K            +V+  G      +L    F +   P     +EG    K D   +   + + ++  +     G+ + +GHG     ++  + K  EKV  ++R K+ D++    H +   ++  +YSW
Sbjct: 4214 EKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEIIDIAAGGSHSAAISRSGELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWGDG-DYGKLGRGGFDICKLPMKIETLEGAGVIKVDCGSQFS-LVLTASGEVYTWGKGDYFRLGHG-----SDNHVRKP-EKVAQLNRKKIIDVACGSLHCICCTEDGEVYSW 4465

HSP 9 Score: 54.6842 bits (130), Expect = 1.054e-6
Identity = 30/86 (34.88%), Postives = 43/86 (50.00%), Query Frame = 2 
Query: 1376 KIEQLAVGWPILND--SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 1627
            KIE L     I  D  SQ  L LT  G++Y+WG G + +LGHG       P  +  L    I +++CG+ H    +E G  + WG+
Sbjct: 4382 KIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGD 4467

HSP 10 Score: 53.9138 bits (128), Expect = 2.242e-6
Identity = 22/58 (37.93%), Postives = 34/58 (58.62%), Query Frame = 2 
Query: 1418 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 1591
            S H +  T+ G++YSWG    G+LG G       P +IE+L G  I  ++CG++H+ A
Sbjct: 4450 SLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLA 4507
[Close]
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Planmine SMEST
Match: SMESG000033113.1 (SMESG000033113.1)

HSP 1 Score: 63.5438 bits (153), Expect = 1.767e-9
Identity = 64/247 (25.91%), Postives = 110/247 (44.53%), Query Frame = 2 
Query: 1379 IEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG-NPHAFNSKDENCLFPVRLRQAIMS----SIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAXXXXXXXXXXXXXXXYSIGHGINLGCTECQIHKTFEKVQCMSRH----KVFDISLSENHIVILG-QNVIYSWS 2089
            IE+++ G+       H L L ++G+LYS G   F KLGH    +K  P  I+ L  + + + S G  H++ V++ GL F WG N      +D+   F ++L Q++       + CG   T  L+ N     +  + C +  L   +F +   P  I+ L       +  I+ I        VL  +G LYS G   N G     +  ++E +  M +H     +  +S+ +NH+  L     +++W 
Sbjct:  171 IEKISCGF------DHTLFLLKNGKLYSCGNNEFKKLGHD--CNKFKPNQIQMLDAHKLIDASAGYDHNAVVTDLGLVFTWGKNSFGELGRDKLSDFSIKLVQSLTGHFIVQVACGHDHTLALTKNSEIFSWGANTCGQLGL-GDNFDMVSTPQQIKNL------SNLPIKSITAGDKFSFVLTPSGFLYSWGSN-NYGQLGRDLTTSYESLPLMVKHLRKQPIVYVSVGQNHVAALSIDGGVFTWG 401

HSP 2 Score: 52.7582 bits (125), Expect = 3.916e-6
Identity = 23/68 (33.82%), Postives = 40/68 (58.82%), Query Frame = 2 
Query: 1424 HILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA-VSETGLGFVWG 1624
            H+ AL+  G +++WG G +G+LGH +  +K  P ++  L G  +  I CG +H+ A +  TG  + +G
Sbjct:  387 HVAALSIDGGVFTWGHGRYGQLGHNNFENKSIPCIVMDLLGSKVSQIECGMNHTLAYMVSTGTVYAFG 454
The following BLAST results are available for this feature:
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HERC13.512e-1529.82HECT and RLD domain containing E3 ubiquitin protei... [more]
HERC24.966e-1247.06HECT and RLD domain containing E3 ubiquitin protei... [more]
HERC25.461e-1247.06HECT and RLD domain containing E3 ubiquitin protei... [more]
HERC22.981e-1146.38HECT and RLD domain containing E3 ubiquitin protei... [more]
HERC21.166e-1028.10HECT and RLD domain containing E3 ubiquitin protei... [more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
K11D2.11.984e-628.21pep chromosome:WBcel235:I:12504117:12505010:1 gene... [more]
K11D2.12.271e-628.21pep chromosome:WBcel235:I:12497467:12505010:1 gene... [more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HERC22.870e-1450.00gene:FBgn0031107 transcript:FBtr0301344[more]
Herc41.929e-824.24gene:FBgn0035207 transcript:FBtr0072670[more]
Herc41.929e-824.24gene:FBgn0035207 transcript:FBtr0072671[more]
Herc43.795e-827.95gene:FBgn0035207 transcript:FBtr0310555[more]
CG66782.382e-731.73gene:FBgn0038917 transcript:FBtr0084148[more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
herc15.787e-1630.70HECT and RLD domain containing E3 ubiquitin protei... [more]
herc15.787e-1630.70HECT and RLD domain containing E3 ubiquitin protei... [more]
herc21.291e-1247.06HECT and RLD domain containing E3 ubiquitin protei... [more]
si:ch211-281g13.48.317e-1225.63si:ch211-281g13.4 [Source:ZFIN;Acc:ZDB-GENE-090311... [more]
herc21.071e-1124.45HECT and RLD domain containing E3 ubiquitin protei... [more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HERC15.871e-1530.00HECT and RLD domain containing E3 ubiquitin protei... [more]
HERC15.872e-1530.00HECT and RLD domain containing E3 ubiquitin protei... [more]
HERC22.962e-1247.06HECT and RLD domain containing E3 ubiquitin protei... [more]
HERC22.963e-1247.06HECT and RLD domain containing E3 ubiquitin protei... [more]
HERC22.966e-1247.06HECT and RLD domain containing E3 ubiquitin protei... [more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Herc12.126e-1530.26HECT and RLD domain containing E3 ubiquitin protei... [more]
Herc23.747e-1247.06HECT and RLD domain containing E3 ubiquitin protei... [more]
Herc23.749e-1247.06HECT and RLD domain containing E3 ubiquitin protei... [more]
Herc23.749e-1247.06HECT and RLD domain containing E3 ubiquitin protei... [more]
Herc27.193e-1123.63HECT and RLD domain containing E3 ubiquitin protei... [more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q15751|HERC1_HUMAN1.687e-1429.82Probable E3 ubiquitin-protein ligase HERC1 OS=Homo... [more]
sp|Q9VR91|HERC2_DROME2.877e-1350.00Probable E3 ubiquitin-protein ligase HERC2 OS=Dros... [more]
sp|O95714|HERC2_HUMAN2.622e-1147.06E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens ... [more]
sp|Q4U2R1|HERC2_MOUSE2.622e-1147.06E3 ubiquitin-protein ligase HERC2 OS=Mus musculus ... [more]
sp|Q4R828|RCCD1_MACFA2.642e-1039.77RCC1 domain-containing protein 1 OS=Macaca fascicu... [more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
J9JPA79.639e-2024.37Uncharacterized protein OS=Acyrthosiphon pisum OX=... [more]
A0A2S2PMV12.517e-1824.33Putative E3 ubiquitin-protein ligase OS=Schizaphis... [more]
A0A2S2QPE53.244e-1824.71Putative E3 ubiquitin-protein ligase OS=Sipha flav... [more]
A0A5E4MJB64.072e-1823.54Concanavalin A-like lectin/glucanase domain,WD40-r... [more]
A0A5E4MP694.085e-1823.54Uncharacterized protein OS=Cinara cedri OX=506608 ... [more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
herc21.094e-1247.06HECT and RLD domain containing E3 ubiquitin protei... [more]
ENSAMXT00000005642.26.020e-1127.80pep primary_assembly:Astyanax_mexicanus-2.0:25:494... [more]
ENSAMXT00000020522.25.423e-1028.51pep primary_assembly:Astyanax_mexicanus-2.0:25:755... [more]
ENSAMXT00000051376.11.892e-944.78pep primary_assembly:Astyanax_mexicanus-2.0:14:343... [more]
rccd15.371e-937.68RCC1 domain containing 1 [Source:NCBI gene;Acc:103... [more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000001275.11.435e-1530.30pep scaffold:Pmarinus_7.0:GL476529:184068:212443:-... [more]
rcc21.982e-931.25regulator of chromosome condensation 2 [Source:NCB... [more]
ENSPMAT00000001750.11.193e-848.44pep scaffold:Pmarinus_7.0:GL481695:1137:12922:1 ge... [more]
ENSPMAT00000002333.12.950e-724.62pep scaffold:Pmarinus_7.0:GL483648:23119:25960:-1 ... [more]
ENSPMAT00000002332.14.045e-724.10pep scaffold:Pmarinus_7.0:GL483648:174:5242:1 gene... [more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO455791.672e-1731.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO371961.162e-1639.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO455832.514e-1625.37Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO447042.990e-1227.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO465287.504e-1028.68Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
herc29.072e-1228.79HECT and RLD domain containing E3 ubiquitin protei... [more]
rccd12.467e-1138.64RCC1 domain containing 1 [Source:NCBI gene;Acc:101... [more]
herc38.987e-1125.22HECT and RLD domain containing E3 ubiquitin protei... [more]
herc39.078e-1125.22HECT and RLD domain containing E3 ubiquitin protei... [more]
herc39.237e-1125.22HECT and RLD domain containing E3 ubiquitin protei... [more]
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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000006057.16.891e-2799.07SMESG000006057.1[more]
SMESG000006057.16.944e-2799.07SMESG000006057.1[more]
SMESG000006057.11.214e-1199.12SMESG000006057.1[more]
SMESG000054104.11.559e-1130.53SMESG000054104.1[more]
SMESG000033113.11.767e-925.91SMESG000033113.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004625 ID=SMED30004625|Name=HECT and RLD domain containing E3 ubiquitin protein ligase family member 1|organism=Schmidtea mediterranea sexual|type=transcript|length=6414bp
ATGTAAAATGCCTTATATGAACTTCAATTTTTATTAATAATAGTTAATTA
TTTATATTTAATATTTGAATAAGTATTACGCTCAATAGTCATAAAATATT
AAATCAGTTATGAATTATGATATTTTTAATTACAAAAAAGGCTGTGAAGT
CAAAACGGACCATACAGAAAATTGCATCATGAATAATGATTTACCGAACA
AATATATAAATTTTTCAAACCAATTTTCTAAATCTTATCACTATGAAAAT
CAGGAAATCACAAAAGAAATCAGTTTTAATATTAATCATAAATCTGAATT
ATTCAATGTAATCATTACCAATACTCCTTTCTACAACTTTATTGAGCATT
TTAAAAGCGATTTTATTCAAGATATTAATAAATTGAAAGAGTTGGAAGTT
ATCTACAAAGATGGTAATAGTACTTGTAATGATATTGTAAAATCAAACAA
TAATGGAAGCAAAGAATTCATATTAATTGAAAAGCAACAAAATCAGATAA
TTGATGTATCTATTTCTAAGATACTAAAAGTGCTCTTATCTACAGTAAAG
TGCCACTTAATTGCGTCAAATAACGAATTTAATAGTGATAATGACGTTTT
TAAAATTATTGAAGACTCGATTAAAGAATTACCGTTATTAATCTTGTCCA
AAGTTATAAATGAATCTCATGAATCAAGTATTACAGAAATTAAAAAATTC
ATACATGAAATAATAGAAGCAAATGCCAATTATTGGAGTTACAAAAGTGC
GGTTGAAATCTGGTTGCTATTATTCACGAGAATCGGTAGCTTAGACAACA
TTCTGGAATGGTTCTGTTTAGTAATCCAACAAATAGACTCGGAAAATGAT
GTATTAATCAGGACTGAAATCTTGAGCAGTGTGTTCGAATCTCTGTTCAA
TGGAGAAGGCCAGTTAAATGCTGAAATCAAAGAAAATATGATGGATTGTC
TAGAGATTGATATTTTAGAACAAGAATTTATTGGATTAACGCAGGCCATC
AATTTTATATTTTTGGGGGTACTAAGAGCGTTCAAAGTTCATTCTAAGCA
TCGTCAAGGAATCCATGAAACGAAGAAATTAAACAATGATACTAAAAATG
ATCCCTTTAAAGACATTTATATTTGGGAACATGGAAGGAAATTAGAAACT
CTTAAAGCTCCTTATAATGATAGTTTATTGACTCGTTTGAGCTGTTCGAA
GGAAAATCATTCTGTTAGAGAAATAATTTGTTCTGAAAATGAAATAATTG
TATTGAATAACCTCGGCCAAATTCGGAGTAGAAGTATTTCGCCTCCTAGT
ACCAAAAAACATGAAAATATTGTTATGCTGTTCCATCAATGCTGGTCTCC
TATTAATTTTCCTGATGTAAAATGTAAAATCGAGCAATTAGCAGTCGGCT
GGCCTATTCTGAACGACAGTCAACATATATTAGCTTTGACCCAACATGGC
CAATTATATAGTTGGGGTGGTGGAAGCTTTGGGAAATTAGGCCATGGGGA
TATGCTTGATAAACATTCCCCAACTCTGATCGAGGCTCTCCGTGGATATA
ACATCCGAAATATTTCATGTGGAGCTAGCCATTCCTCAGCTGTCAGTGAA
ACTGGACTGGGATTTGTTTGGGGAAATCCTCATGCATTTAATAGTAAAGA
CGAAAACTGCTTATTTCCAGTTAGACTTCGCCAAGCTATCATGTCGAGTA
TTGTCTGTGGTCCGCATTCTACTTTCTTTTTGAGTATTAATAAAAGAAAT
GTGTATTATCTTGGATCACAATGTTCAGAAAACGAACTTTTTACCAAAGA
TTTCATTCTACAGCATTATCCAAGTATTATTGAAGGACTTCCGTTTACAA
AATGTGATAAAAGTGAAAAAATTGAGAAAATTGCTGTGAATTCCACTGTT
GTGCTTGTTCTGTTGAATAATGGCAATCTATATTCTATTGGACATGGAAT
AAATTTAGGATGCACAGAATGTCAAATTCACAAAACATTTGAGAAAGTAC
AATGTATGTCTCGTCATAAGGTCTTCGATATTTCACTATCTGAAAATCAT
ATTGTTATCCTTGGTCAAAATGTTATATATTCTTGGTCATTAACTGCAGA
AACATTTTCCTTCATTGAAGAGCCATTTGATTATTCAATTACAGCAATAT
CGTCAACATCACTCATAAATCACAATAAACTGATTAATATTGCTTGGAGT
AGAAATTCTGAAGGTATACAAGAAACTCCAAATTTACTAAGTCAATGTGA
TAACCCTTATTTATCAATAATTTCCATTTCAAACAGCATGAATTATTTCT
GTGATATCTTAGAAAGGTCTTTCATTTTATGGAATACTTCAAAATATTTT
GAACAAATCCTTCCTAACACTTTGAAGTTGTTTTTACAATTCATACGAAG
TAATCAGTTTGCAAATTTAATGGACAGAGGTACTGATCTCAAATCAACGA
TAAATAAATTGTTAAAATTTATTTTGAAAATCGGAGATCACGAAAATTTT
ACTAAAAATAAAAAGATCGTTATCCAAATCCTAAATGAAATATGCTCGAA
GCTACTTAAAATAGAAGACAAAGCAGAATGTATTTGTGATATATTGAGCA
AAAATTTGAGTTCATTAAGTTTTTGTAGCCGATATTTTTTAAAAACTTTA
ATCCTTTCACTCAATGATACATCAAATAATACTCTATTCATAAAGCTATT
TCAATTAGAATTTTCAAAAATCAGTGATTTGCTGATCGCCGTTTGTCAGA
ATTTGTCCAATTATACTATAAACGTTTTGCAAAATAAAATGAATTTTAAT
CGTTCAGAAAATCTAGACGAATCCGTTTATGAAATAATTGAGTTAATTCA
TCAATTTTCAATTGCTGGTTACAGAATATATTTTTCATTAGTATTAAAAT
ATTTTGATAACTCACATAATCCAATTTCTAATTTTTGCTGTCTATTTCCT
TTGATGAACAGCATTATTGGCTGCTTTAAATCGTATTTGCTTACGGCTGT
GAAATTGCAAAAAATAAACCAATGGATCAAAGGCAGGGGAGTTGAAATAA
ATCTGCTTTTATCTAAATCTCCTATAAGTTGGATCTTGTTTGATGTTTTA
AATTATTTAAATGAGCAACATAACTTGGATATATTACCGTTACTTCCTCA
TATAGAACGATTAATTTTAATTCTGGATTCGATAAACATAATTTTGCCAA
AAACATTCAATAATGATACACAGGAAATTCAATGGCCTCTTTATGGATTT
TCAGCTTTTCCTAATACATCTAACATTGTTCCCGAACCCGGATTAACTTG
GTTGTGGCTTTTAGACTTACAACGATTGACTGGATTAGTGTTAGGAAATA
TCTTCAGGAAACAATTAACTTTACCTTTATCAAATGAAAATGCCGAGGAT
AAAAGCTTGTTTACAACATTGTTAGAAACTTCACTTTTTAAATATATTAT
CACATTGCCCATTTGTCAAGTAAATGATGCTCACCGTATATTTAATTGCA
TTTGTAAACAAATTTCGGTTCAATTAATTTCAGGCTATGCGAAATTATCA
GCGAGTTACAATGACCTATTAACTTTTATGAAAATTGGGCAAGGTGTTCA
GTTTTGTGCGTGGTCGGACAAAAACTTTATGTATTTTACTGGTTTACAAA
TCTATGAAATTATTATACAATTATTGAGCAATAAGTTTCTACTAATAGAT
TTTCGCAATTCCATTTTTGTGTATTATGCTATGAGAAAAATTATGAATAT
CATTACAAAACATGCAACCGAATGTTTCGGGATAAATTTATCATCTGCTG
ATAATGAAATGACTGAAGTTCAATCAAACAGTTTCAGAAACTGCATTGAT
ATTCTCAATAAAAAATGCAATTTTCTAACAAGTTTGTTGAAAGATTCTAT
GGAAACTTGTGATCTAACTACATTTCCCGAGGAGTCGGAATTAATTGAGG
CACTGGATTTGAGAAAAATAAATGTAAAATTAGTTTCAAATTGTCTTTCA
AGTGCTACCAATTTCCGCGCATCATCAAATCGGATCTTTGATATGTATAC
AGCAAAATTACCTGAAAAAAAGATATTGAAATTTTTGAAGGAAAACCTAG
ACATTCTTGGAATGTTTTTAGTGATGAACACACATTTTAAAAATGATGTT
GTAGATGAGACAAATACCTTTTTGCATCATCTTTCTAGTAAAATATTTTT
CAAGAGACGGTCTTTGGATAGAATAACTAAAGTTTTTCTGAGTTTCTCTA
AGCTTTTAGATTCTTCAAAATTATCTGTTAATTCTGTGTTTCTTCAAATT
TTGAATGCTATGCTAATTTCACCGCCGTCTTTGAAAAACCAAATTTATGA
TTGTCATATCGAAATAATGGAGAAAATATTTATTTCATTAATAGATAAAT
TTAACAATAATTTTAGCAATGCTCTACTTAATGAATCATCGACAATACTG
TCTCAAAGAATTTCTATCGCTCTCTTTAATTTCCTGTCAAGCTATCACTC
TGGATTCATCCCATTGGTCAATATTCTAATAGACCACAACTTTATTAATT
TGATAATGCGTTCCGGAAACGATCGTTTATTAATATCCAATGAAAAGTGG
TTAATTATTGAAGGAAATGGCGATAATAATTTACCGAAAGTTTGTAATAT
GATTGCCTGGTGCATAATGGAGAATTTTATTTTAAATATAAGTATGTGTG
AAGATAAAATTACGAGAGAAAGAATGATTCTTTTGGAAGATCAGTTTCTT
CAATCACTGCGTCAAATTTACTGCGGTTTTACTAATGAAAAAATATATCA
AATATTTGATTTATACTATTTACTAAAAGTTATCAATTATTTTTATAACA
AATCGGAGAGTTTTCGAAACATTTGTCAAAATGAGGCTTGGATAAAGATG
CTTTTGGAAATTTCAACAGATCTTTGTCACTCGGAGGAAAGATCTATTTT
TTATTTCAATTACAATTTAAATATTGTTGCTATAAAATTTTTGTTCTCAA
TAATTTCTCATCGAGCAAAACAAGGTTCTGGAGAATTTCAAGACAGCTCT
AATATATCTTACTTGGAAATATTTCAAAAATTTTCTGAATTTTTTTATAA
CTTGATAACAAAATCTACGAAACTCGATATAATTAGAATCACCAACAACA
TGACGAAGAGAATCGAGTTCTATAAGCATTTTGGGGATGAATTAAACTCT
TGTGAGAATAATGATAGATTTGATTGGATTTTCGGGAATTGTAATTTCGA
TAAACAACGCTCATTCTTTTGCAACTTTAAATCTAGTGACAAAATTTCTA
TAACTAATGCGGATTTCAGTGATAGTGGAGTTATTGTTCTCAATTCCGAG
AATCTGTTCAGTGGGATCTGGCACATCACATTTGATATCGAATGTGTCAA
AAATTCAATTGATTTTAATTACGGATTTTTGATAAATCCAACTAAAAAAT
GGCCAAAAGATTATACATCAATAAAGAAATTAGTGAAACAATGTTCTTCC
ATGTCCATTTCATGCCGTTCAGCCACGTCCTACCGCCTAAGCTGTGTGAT
TGACATTGATCAATCTTTTCTATGTTTCTCGAACAGTAACAATCGTATCC
AAACATTCACAAATAGTAATGGGGTTTTCAGATTTTTTATTTCTTCTTCA
ATGAATTTCCATGGTTCTTTTGAAATTCAAATGATATCCGTGAAACAATT
GCGCTTATCTGAAATGTATGATGACGTTGAGTTCTATAATAATACTCAGA
TATCACCGGATTATTATCTTGTTTTGAAGCATCTCTATGTTGAGTTCAAT
AATTTTTTTGCAGTTATTCCTGACATATATTTATATGAAATTGTTGGAGT
GTTATTAGAAAAATCTATTTATATAAATCAATTCGATTTGTATTTTGATA
AAAATGTAAGATATTTTTTATTTTTGAACCGTAAATATTATATATATAAC
CAAAAAATATGCAGTCCGAATCACGAGGAACACATGAAATACATCCTGTT
CTATGACAAATAAGCACACAATTTTCAGTTAATTCCATTTTGGTGTATTT
TATTAGCAACAACAAAAATTTCACCTGAATGACTTTCAAAATGAATTATA
AAAGATTCAATTTGAAAATGGTGTTTCTGTAGTATTTATAGGTGTGTGTA
TTAATTACATTTTTGTTTGTGTACAAGTGGATTTGTGTTCGGGGACGAAA
CCGGCTTACAAATGCTATTCAAATACTACTTGGAGTGACCAGGAGATTCG
TATTGCAGTAGCAAAATAGGAACACTGGATCCTGTGTCAGTGACAAAATC
AACTGTGTTTGAAAAGTTTGGAGCGACGCTGAAAGACGGGGATTTGGGCA
TGGCAAAAAAAGTCATGTTCTGGAGGAAGTTTGCCATCGACCTCAGCCTC
AAGAAGAACTGTAG
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protein sequence of SMED30004625-orf-1

>SMED30004625-orf-1 ID=SMED30004625-orf-1|Name=SMED30004625-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1968bp
MNYDIFNYKKGCEVKTDHTENCIMNNDLPNKYINFSNQFSKSYHYENQEI
TKEISFNINHKSELFNVIITNTPFYNFIEHFKSDFIQDINKLKELEVIYK
DGNSTCNDIVKSNNNGSKEFILIEKQQNQIIDVSISKILKVLLSTVKCHL
IASNNEFNSDNDVFKIIEDSIKELPLLILSKVINESHESSITEIKKFIHE
IIEANANYWSYKSAVEIWLLLFTRIGSLDNILEWFCLVIQQIDSENDVLI
RTEILSSVFESLFNGEGQLNAEIKENMMDCLEIDILEQEFIGLTQAINFI
FLGVLRAFKVHSKHRQGIHETKKLNNDTKNDPFKDIYIWEHGRKLETLKA
PYNDSLLTRLSCSKENHSVREIICSENEIIVLNNLGQIRSRSISPPSTKK
HENIVMLFHQCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLY
SWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGL
GFVWGNPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYY
LGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLV
LLNNGNLYSIGHGINLGCTECQIHKTFEKVQCMSRHKVFDISLSENHIVI
LGQNVIYSWSLTAETFSFIEEPFDYSITAISSTSLINHNKLINIAWSRNS
EGIQETPNLLSQCDNPYLSIISISNSMNYFCDILERSFILWNTSKYFEQI
LPNTLKLFLQFIRSNQFANLMDRGTDLKSTINKLLKFILKIGDHENFTKN
KKIVIQILNEICSKLLKIEDKAECICDILSKNLSSLSFCSRYFLKTLILS
LNDTSNNTLFIKLFQLEFSKISDLLIAVCQNLSNYTINVLQNKMNFNRSE
NLDESVYEIIELIHQFSIAGYRIYFSLVLKYFDNSHNPISNFCCLFPLMN
SIIGCFKSYLLTAVKLQKINQWIKGRGVEINLLLSKSPISWILFDVLNYL
NEQHNLDILPLLPHIERLILILDSINIILPKTFNNDTQEIQWPLYGFSAF
PNTSNIVPEPGLTWLWLLDLQRLTGLVLGNIFRKQLTLPLSNENAEDKSL
FTTLLETSLFKYIITLPICQVNDAHRIFNCICKQISVQLISGYAKLSASY
NDLLTFMKIGQGVQFCAWSDKNFMYFTGLQIYEIIIQLLSNKFLLIDFRN
SIFVYYAMRKIMNIITKHATECFGINLSSADNEMTEVQSNSFRNCIDILN
KKCNFLTSLLKDSMETCDLTTFPEESELIEALDLRKINVKLVSNCLSSAT
NFRASSNRIFDMYTAKLPEKKILKFLKENLDILGMFLVMNTHFKNDVVDE
TNTFLHHLSSKIFFKRRSLDRITKVFLSFSKLLDSSKLSVNSVFLQILNA
MLISPPSLKNQIYDCHIEIMEKIFISLIDKFNNNFSNALLNESSTILSQR
ISIALFNFLSSYHSGFIPLVNILIDHNFINLIMRSGNDRLLISNEKWLII
EGNGDNNLPKVCNMIAWCIMENFILNISMCEDKITRERMILLEDQFLQSL
RQIYCGFTNEKIYQIFDLYYLLKVINYFYNKSESFRNICQNEAWIKMLLE
ISTDLCHSEERSIFYFNYNLNIVAIKFLFSIISHRAKQGSGEFQDSSNIS
YLEIFQKFSEFFYNLITKSTKLDIIRITNNMTKRIEFYKHFGDELNSCEN
NDRFDWIFGNCNFDKQRSFFCNFKSSDKISITNADFSDSGVIVLNSENLF
SGIWHITFDIECVKNSIDFNYGFLINPTKKWPKDYTSIKKLVKQCSSMSI
SCRSATSYRLSCVIDIDQSFLCFSNSNNRIQTFTNSNGVFRFFISSSMNF
HGSFEIQMISVKQLRLSEMYDDVEFYNNTQISPDYYLVLKHLYVEFNNFF
AVIPDIYLYEIVGVLLEKSIYINQFDLYFDKNVRYFLFLNRKYYIYNQKI
CSPNHEEHMKYILFYDK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004842ubiquitin-protein transferase activity
GO:0016740transferase activity
GO:0003674molecular_function
Vocabulary: biological process
TermDefinition
GO:0016567protein ubiquitination
GO:0008150biological_process
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR000408Reg_chr_condens
IPR009091RCC1/BLIP-II
IPR013809ENTH
Vocabulary: cellular component
TermDefinition
GO:0005829cytosol
GO:0005886plasma membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR009091Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein IIGENE3DG3DSA:2.130.10.30coord: 334..670
e-value: 1.8E-36
score: 127.7
IPR009091Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein IISUPERFAMILYSSF50985RCC1/BLIP-IIcoord: 365..653
IPR000408Regulator of chromosome condensation, RCC1PFAMPF00415RCC1coord: 447..495
e-value: 1.5E-11
score: 44.8
IPR000408Regulator of chromosome condensation, RCC1PROSITEPS50012RCC1_3coord: 447..498
score: 16.172
NoneNo IPR availablePANTHERPTHR22870REGULATOR OF CHROMOSOME CONDENSATIONcoord: 298..659
NoneNo IPR availablePANTHERPTHR22870:SF330E3 UBIQUITIN-PROTEIN LIGASE HERC2coord: 298..659