SMED30004578

Overview
NameSMED30004578
Smed IDSMED30004578
Length (bp)1283
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30004578 (SMED30004578) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30004578 (SMED30004578) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30004578 (SMED30004578) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30004578 (SMED30004578) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30004578

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30004578h1SMcG0004593 dd_Smed_v4_3986_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30004578h1SMcG0004593 dd_Smed_v4_3986_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30004578 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.013794:6722..8033 +6320
Homology
[Close]
BLAST of SMED30004578 vs. Ensembl Human
Match: PSMD6 (proteasome 26S subunit, non-ATPase 6 [Source:HGNC Symbol;Acc:HGNC:9564])

HSP 1 Score: 479.945 bits (1234), Expect = 1.026e-168
Identity = 231/393 (58.78%), Postives = 302/393 (76.84%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAF-----QYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP+EN EEEGL K PDLR+ Q  F     +++ D +    ++D+L+  +  N+M PYYE + + L+  +D  LL KMK ANED+LK LD  +++AE+N G++E+R+AM+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV  SMI+L+R DLR+KV++G+EILEVLHSLP+V+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRI AY Q LESY SL++  M++ FG+ +EF+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:    1 MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAA----VRDELMAAVRDNNMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 389
[Close]
BLAST of SMED30004578 vs. Ensembl Human
Match: PSMD6 (proteasome 26S subunit, non-ATPase 6 [Source:HGNC Symbol;Acc:HGNC:9564])

HSP 1 Score: 454.521 bits (1168), Expect = 6.936e-158
Identity = 231/446 (51.79%), Postives = 302/446 (67.71%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAF-----QYKCDVSNKHQIKDKLIEVITLND-----------------------------------------------------MGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP+EN EEEGL K PDLR+ Q  F     +++ D +    ++D+L+  +  N+                                                     M PYYE + + L+  +D  LL KMK ANED+LK LD  +++AE+N G++E+R+AM+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV  SMI+L+R DLR+KV++G+EILEVLHSLP+V+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRI AY Q LESY SL++  M++ FG+ +EF+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:    1 MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAA----VRDELMAAVRDNNFWNRIRQEQTEDCPPSSPSRGWHCQDWPSRKPPTSIRLCFAKPIIKRHRMPSYMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 442
[Close]
BLAST of SMED30004578 vs. Ensembl Human
Match: PSMD6 (proteasome 26S subunit, non-ATPase 6 [Source:HGNC Symbol;Acc:HGNC:9564])

HSP 1 Score: 450.284 bits (1157), Expect = 1.366e-157
Identity = 212/341 (62.17%), Postives = 271/341 (79.47%), Query Frame = -3 
Query:   37 DMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1059
            DM PYYE + + L+  +D  LL KMK ANED+LK LD  +++AE+N G++E+R+AM+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV  SMI+L+R DLR+KV++G+EILEVLHSLP+V+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRI AY Q LESY SL++  M++ FG+ +EF+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:   10 DMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 350
[Close]
BLAST of SMED30004578 vs. Ensembl Human
Match: PSMD6 (proteasome 26S subunit, non-ATPase 6 [Source:HGNC Symbol;Acc:HGNC:9564])

HSP 1 Score: 449.899 bits (1156), Expect = 2.073e-157
Identity = 212/341 (62.17%), Postives = 271/341 (79.47%), Query Frame = -3 
Query:   37 DMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1059
            DM PYYE + + L+  +D  LL KMK ANED+LK LD  +++AE+N G++E+R+AM+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV  SMI+L+R DLR+KV++G+EILEVLHSLP+V+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRI AY Q LESY SL++  M++ FG+ +EF+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:   11 DMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 351
[Close]
BLAST of SMED30004578 vs. Ensembl Human
Match: PSMD6 (proteasome 26S subunit, non-ATPase 6 [Source:HGNC Symbol;Acc:HGNC:9564])

HSP 1 Score: 201.06 bits (510), Expect = 9.081e-62
Identity = 94/163 (57.67%), Postives = 126/163 (77.30%), Query Frame = -3 
Query:  568 MGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYE 1056
            M PYYE + + L+  +D  LL KMK ANED+LK LD  +++AE+N G++E+R+AM+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYE
Sbjct:   64 MAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYE 226
[Close]
BLAST of SMED30004578 vs. Ensembl Celegans
Match: rpn-7 (26S proteasome non-ATPase regulatory subunit 6 [Source:UniProtKB/Swiss-Prot;Acc:Q20585])

HSP 1 Score: 351.288 bits (900), Expect = 2.922e-118
Identity = 183/398 (45.98%), Postives = 258/398 (64.82%), Query Frame = -3 
Query:   40 PVE--NFEEEGLEKIPDLRLPQWAF---QYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVL------HSLPSVKEFLMSLYECRYSDFFRYLAGIEN-YMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVIN 1197
            PV+  NF++E + + PDL L Q  F     + D S K    +KL E I   DM P+YE++  +  I +D + L  MK+AN+ K+ E+   +++AE+N G++EVR+ ++ K  Y  +IG ++ AL  +    EKT+ +GYR+D+ F +IR+G FF D  LI K I KA  L+E+GGDW+R+NRL+ Y+ LY +S+R+F  AA+ FLEAV TF SYELM Y+  I+YTV+ +  +L R DLR KV+R +E+ E L       +L  V+E+L S Y+C Y  FF  LA +E+   K D YL PH+ YY R MR  AY+Q L  Y ++ +  M+K FG+S  F+D EL R I+ G+L C+ID VNG+IE    DS N  Y++VIK GDILLNRIQKL+RVIN
Sbjct:   12 PVDDGNFDKEIISRWPDLELSQTRFMLNHPEVDSSVKEAKLEKLQETIKEFDMAPFYELVCADFKIVVDATQLAAMKAANQKKIDEITAEVEDAEKNLGESEVRQGLLRKFEYYCQIGDKDNALKAYTATYEKTVGMGYRIDVVFAMIRVGLFFLDHHLINKFITKAKELMEQGGDWERKNRLRSYEALYRMSVRDFAGAADLFLEAVPTFGSYELMTYENLILYTVITTTFALDRPDLRTKVIRCNEVQEQLTGGGLNGTLIPVREYLESYYDCHYDRFFIQLAALESERFKFDRYLSPHFNYYSRGMRHRAYEQFLTPYKTVRIDMMAKDFGVSRAFIDRELHRLIATGQLQCRIDAVNGVIEVNHRDSKNHLYKAVIKDGDILLNRIQKLARVIN 409
[Close]
BLAST of SMED30004578 vs. Ensembl Celegans
Match: csn-1 (COP9 signalosome complex subunit 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9GS00])

HSP 1 Score: 56.6102 bits (135), Expect = 2.125e-8
Identity = 33/134 (24.63%), Postives = 67/134 (50.00%), Query Frame = -3 
Query:  142 IYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGII 543
            IY +L++M ++ R+DL+ +V       ++L S P + E L S    R+   F  +  ++  + +D ++  +      ++R     Q+L+ Y+++ +  M++  G+S   L   L   I    ++ KIDQ  GI+
Sbjct:  360 IYGMLSAMATMSRADLKLQVSGNGTFRKLLESEPQLIELLGSYTSSRFGRCFEIMRSVKPRLLLDPFISRNVDELFEKIRQKCVLQYLQPYSTIKMATMAEAVGMSSAELQLSLLELIEQKHVSLKIDQNEGIV 493
[Close]
BLAST of SMED30004578 vs. Ensembl Fly
Match: Rpn7 (gene:FBgn0028688 transcript:FBtr0084294)

HSP 1 Score: 452.595 bits (1163), Expect = 2.625e-158
Identity = 219/393 (55.73%), Postives = 292/393 (74.30%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAF-----QYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP EN EE+GLEK P+L L Q  F     +YK D +    +K KL+E I   +M P+YE I  EL   +D  LL +MK  N  ++++LD  I++AE+N G+ EVREA + K+ YL +IG +  A   F    EKT+ LG+RLD+ FHLIR+G F+ D  LIT+NI+KA  LIEEGGDWDRRNRLKVY+G+YS+++R+F+ AA  FL+ V+TFTSYELMDY TF+ YTV  +MI+L R++LRDKV++GSEI EVLH LP VK+FL SLY C+Y +F+ +LAG+E  +++D  + PHYRYY+REMRIL Y Q LESY SL++  M++ FG+++E++D EL+RFI+ GRL  K+D+V GI+ET RPD+ N QYQ+ IK GD+LLNRIQKLSRVINI
Sbjct:    1 MPAENLEEQGLEKNPNLELAQTKFLLTLAEYKQDAA----LKAKLLEAIRTENMAPWYEHICSELGWTVDKDLLARMKENNRVEVEQLDAAIEDAEKNLGEMEVREANLKKSEYLCRIGDKAAAETAFRKTYEKTVSLGHRLDIVFHLIRLGLFYLDHDLITRNIDKAKYLIEEGGDWDRRNRLKVYQGVYSVAVRDFKAAATFFLDTVSTFTSYELMDYPTFVRYTVYVAMIALPRNELRDKVIKGSEIQEVLHGLPDVKQFLFSLYNCQYENFYVHLAGVEKQLRLDYLIHPHYRYYVREMRILGYTQLLESYRSLTLQYMAESFGVTVEYIDQELARFIAAGRLHAKVDRVGGIVETNRPDNKNWQYQATIKQGDLLLNRIQKLSRVINI 389
[Close]
BLAST of SMED30004578 vs. Ensembl Fly
Match: CSN1b (gene:FBgn0027057 transcript:FBtr0075074)

HSP 1 Score: 89.7373 bits (221), Expect = 4.903e-19
Identity = 75/309 (24.27%), Postives = 142/309 (45.95%), Query Frame = -3 
Query:   85 KMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKA-HYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIE--EG---GDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHG 990
            KMK A   KL++LD+++KN + N     +R      A HYLS  G    AL  ++   +      + +++  ++I++  +  +   +   I KA +  +  EG    +     RL+   GL  L  ++++ AA HFL A      + E++      +Y  L ++ +  R +L+  V+  +     L   P +++ +   YE +Y+     L  I + + +D Y+ PH      ++R  A  Q+   Y S  +  M+  F  S+  L+NE+ + I +G++  +ID  N I+     D  NS ++  +  G
Sbjct:  166 KMKKAAL-KLEKLDSDLKNYKSNSIKESIRRGHDDLADHYLS-CGDLTNALKCYSRARDYCTSGKHVVNMCLNVIKVSIYLQNWAHVMSYISKAESTPDFAEGSKEANAQVHTRLECAAGLAELQQKKYKVAAKHFLNANFDHCDFPEMISTSNVAVYGGLCALATFDRQELKRLVIASTSFKLFLELEPQLRDIIFKFYESKYASCLTLLDEIRDNLLVDMYIAPHVTTLYTKIRNRALIQYFSPYMSADMHKMAMAFNSSVGDLENEVMQLILDGQIQARIDSHNKILFAKEADQRNSTFERALIMG 472
[Close]
BLAST of SMED30004578 vs. Ensembl Zebrafish
Match: psmd6 (proteasome 26S subunit, non-ATPase 6 [Source:ZFIN;Acc:ZDB-GENE-040426-1038])

HSP 1 Score: 488.034 bits (1255), Expect = 3.930e-172
Identity = 236/390 (60.51%), Postives = 303/390 (77.69%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAF--QYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP+EN EEEGL K P+LR+ Q  F   ++ D     Q+K +L++ I LN+M PYYE + +EL    D+ LL KMK ANED+LK LD+ +++AE+N G++E+R+AM+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV   MI+LKR DLR+KV++G+EILEVLHSLP+V+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRILAY Q LESY SL++  M++ FG+S EF+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:    1 MPLENLEEEGLPKNPNLRIAQLKFLLTHRQDA----QVKSELMDAIKLNNMAPYYETLCKELKWQADSDLLSKMKKANEDELKRLDDVLEDAEKNLGESEIRDAMMAKAEYLIRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVCMIALKRPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLARVEQEMKQDWLFAPHYRYYVREMRILAYSQLLESYRSLTLGYMAEAFGVSTEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 386
[Close]
BLAST of SMED30004578 vs. Ensembl Zebrafish
Match: gps1 (G protein pathway suppressor 1 [Source:ZFIN;Acc:ZDB-GENE-041111-240])

HSP 1 Score: 92.8189 bits (229), Expect = 6.342e-20
Identity = 71/329 (21.58%), Postives = 150/329 (45.59%), Query Frame = -3 
Query:   55 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANN---LIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKL 1014
            P+D +  E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   + E+ G+ D +N     +LK   GL  L+ R+++ AA  FL+A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  ++ G     R + +
Sbjct:  121 PLDTAWAESTRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQNQAVLTKLKCAAGLAELASRKYKPAAKCFLQASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMNKMAVAFNTTVAALEDELTQLILEGLINARIDSHSKILYARDVDQRSTTFEKSLQMGKEFQRRAKAM 449
[Close]
BLAST of SMED30004578 vs. Ensembl Zebrafish
Match: gps1 (G protein pathway suppressor 1 [Source:ZFIN;Acc:ZDB-GENE-041111-240])

HSP 1 Score: 90.1225 bits (222), Expect = 4.571e-19
Identity = 70/329 (21.28%), Postives = 149/329 (45.29%), Query Frame = -3 
Query:   55 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANN---LIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKL 1014
            P+D +  E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   + E+ G+ D +N     +LK   G   L+ R+++ AA  FL+A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  ++ G     R + +
Sbjct:  124 PLDTAWAESTRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQNQAVLTKLKCAAGKAELASRKYKPAAKCFLQASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMNKMAVAFNTTVAALEDELTQLILEGLINARIDSHSKILYARDVDQRSTTFEKSLQMGKEFQRRAKAM 452
[Close]
BLAST of SMED30004578 vs. Ensembl Zebrafish
Match: gps1 (G protein pathway suppressor 1 [Source:ZFIN;Acc:ZDB-GENE-041111-240])

HSP 1 Score: 90.1225 bits (222), Expect = 5.693e-19
Identity = 67/294 (22.79%), Postives = 136/294 (46.26%), Query Frame = -3 
Query:  160 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANN---LIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKID 1014
            P+D +  E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   + E+ G+ D +N     +LK   GL  L+ R+++ AA  FL+A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID
Sbjct:  121 PLDTAWAESTRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQNQAVLTKLKCAAGLAELASRKYKPAAKCFLQASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMNKMAVAFNTTVAALEDELTQLILEGLINARID 414
[Close]
BLAST of SMED30004578 vs. Ensembl Xenopus
Match: psmd9 (proteasome 26S subunit, non-ATPase 9 [Source:Xenbase;Acc:XB-GENE-5727784])

HSP 1 Score: 474.167 bits (1219), Expect = 7.827e-166
Identity = 226/391 (57.80%), Postives = 300/391 (76.73%), Query Frame = -3 
Query:   37 NIMPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKH-QIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1206
            ++MP+EN EEEGL K PDLR+ Q  F        +   ++ +L+E +T N+M PYYE + + L+  +D  LL KMK ANE++LK LD+ +++AE+N G++E+R+AM+A+A YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA+ FL+ V+TFTSYELMDYKTF+ YTV  SMI+L R DLR+KV++G+EILEVLHSLP+V+++L SLYECRY  FF+ LA +E  +K D     HYRYY+REMRI AY Q LESY SL++  M++ FG+ +EF+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:   43 SLMPLENLEEEGLPKNPDLRIAQLKFLLSLPEHRREVPLRSELMEAVTSNNMAPYYEGLCKHLDWTVDMDLLNKMKKANEEELKRLDDELEDAEKNLGESEIRDAMMARAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKARSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAADLFLDTVSTFTSYELMDYKTFVTYTVYVSMIALDRPDLREKVIKGAEILEVLHSLPTVRQYLFSLYECRYGVFFQSLAAVEQELKKDWLFASHYRYYVREMRIQAYGQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 433
[Close]
BLAST of SMED30004578 vs. Ensembl Xenopus
Match: gps1 (G protein pathway suppressor 1 [Source:NCBI gene;Acc:493337])

HSP 1 Score: 92.0485 bits (227), Expect = 2.162e-19
Identity = 69/319 (21.63%), Postives = 146/319 (45.77%), Query Frame = -3 
Query:   85 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANN---LIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHG 1014
            P+D + +E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   + E+ G+ D +      +LK   GL  L+ R+++ AA  FL A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  ++ G
Sbjct:  194 PLDTTWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQSVLTKLKCAAGLAELAARKYKQAAKCFLLASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMFKMATAFNTTVSALEDELTQLILEGLINARIDSHSKILYARDVDQRSTTFEKSLQMG 512
[Close]
BLAST of SMED30004578 vs. Ensembl Xenopus
Match: gps1 (G protein pathway suppressor 1 [Source:NCBI gene;Acc:493337])

HSP 1 Score: 88.9669 bits (219), Expect = 1.458e-18
Identity = 73/322 (22.67%), Postives = 149/322 (46.27%), Query Frame = -3 
Query:   85 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVR--EAMIAKA----HYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHG 1014
            P+D + +E  +     KL++LD ++KN + N     +R   +++       HYL   G    AL  ++   +      + +++  ++I++ F  +    I  + E    + E+ G+ D +      +LK   GL  L+ R+++ AA  FL A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  ++ G
Sbjct:  105 PLDTTWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRYVHSILGHDDLGDHYLD-CGDLSNALKCYSRARDYCTSAKHVINMCLNVIKV-FKIDSAFAIQSHTESTPEIAEQRGERDSQTQSVLTKLKCAAGLAELAARKYKQAAKCFLLASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMFKMATAFNTTVSALEDELTQLILEGLINARIDSHSKILYARDVDQRSTTFEKSLQMG 424
[Close]
BLAST of SMED30004578 vs. Ensembl Xenopus
Match: gps1 (G protein pathway suppressor 1 [Source:NCBI gene;Acc:493337])

HSP 1 Score: 88.9669 bits (219), Expect = 1.784e-18
Identity = 73/322 (22.67%), Postives = 149/322 (46.27%), Query Frame = -3 
Query:   85 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVR--EAMIAKA----HYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHG 1014
            P+D + +E  +     KL++LD ++KN + N     +R   +++       HYL   G    AL  ++   +      + +++  ++I++ F  +    I  + E    + E+ G+ D +      +LK   GL  L+ R+++ AA  FL A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  ++ G
Sbjct:  161 PLDTTWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRYVHSILGHDDLGDHYLD-CGDLSNALKCYSRARDYCTSAKHVINMCLNVIKV-FKIDSAFAIQSHTESTPEIAEQRGERDSQTQSVLTKLKCAAGLAELAARKYKQAAKCFLLASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMFKMATAFNTTVSALEDELTQLILEGLINARIDSHSKILYARDVDQRSTTFEKSLQMG 480
[Close]
BLAST of SMED30004578 vs. Ensembl Mouse
Match: Psmd6 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 [Source:MGI Symbol;Acc:MGI:1913663])

HSP 1 Score: 476.863 bits (1226), Expect = 1.193e-167
Identity = 229/393 (58.27%), Postives = 302/393 (76.84%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAF-----QYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP+EN EEEGL K PDLR+ Q  F     +++ D +    ++++L+  +  N+M PYYE + + L+  MD  LL KMK ANE++LK LD  +++AE+N G++E+R+AM+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV  SMI+L+R DLR+KV++G+EILEVLHSLP+V+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRI AY Q LESY SL++  M++ FG+ ++F+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:    1 MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAA----VREELMAAVRENNMAPYYEALCKSLDWQMDVDLLSKMKKANEEELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCQIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAIVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVDFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 389
[Close]
BLAST of SMED30004578 vs. Ensembl Mouse
Match: Psmd6 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 [Source:MGI Symbol;Acc:MGI:1913663])

HSP 1 Score: 236.113 bits (601), Expect = 5.032e-76
Identity = 121/244 (49.59%), Postives = 159/244 (65.16%), Query Frame = -3 
Query:  241 EDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSK 972
            E++LK LD  +++AE+N G++E+R+AM+AKA YL +IG +                                                    EGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV  SMI+L+R DLR+KV++G+EILEVLHSLP+V+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRI AY Q LESY SL++  M++
Sbjct:    1 EEELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCQIGDK----------------------------------------------------EGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAIVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAE 192
[Close]
BLAST of SMED30004578 vs. Ensembl Mouse
Match: Gps1 (G protein pathway suppressor 1 [Source:MGI Symbol;Acc:MGI:2384801])

HSP 1 Score: 89.7373 bits (221), Expect = 7.134e-19
Identity = 70/318 (22.01%), Postives = 144/318 (45.28%), Query Frame = -3 
Query:   85 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNL--IEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHG 1014
            P+D + +E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   I E G+ D +      +LK   GL  L+ R+++ AA  FL A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  +  G
Sbjct:  121 PLDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAERGERDSQTQAILTKLKCAAGLAELAARKYKQAAKCFLLASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMHKMAAAFNTTVAALEDELTQLILEGLINARIDSHSKILYARDVDQRSTTFEKSLLMG 438
[Close]
BLAST of SMED30004578 vs. Ensembl Mouse
Match: Gps1 (G protein pathway suppressor 1 [Source:MGI Symbol;Acc:MGI:2384801])

HSP 1 Score: 89.3521 bits (220), Expect = 8.084e-19
Identity = 70/329 (21.28%), Postives = 148/329 (44.98%), Query Frame = -3 
Query:   55 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANN---LIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKL 1014
            P+D + +E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   + E+ G+ D +      +LK   GL  L+ R+++ AA  FL A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  +  G     R + +
Sbjct:  121 PLDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKCAAGLAELAARKYKQAAKCFLLASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMHKMAAAFNTTVAALEDELTQLILEGLINARIDSHSKILYARDVDQRSTTFEKSLLMGKEFQRRAKAM 449
[Close]
BLAST of SMED30004578 vs. Ensembl Mouse
Match: Gps1 (G protein pathway suppressor 1 [Source:MGI Symbol;Acc:MGI:2384801])

HSP 1 Score: 88.9669 bits (219), Expect = 1.101e-18
Identity = 69/319 (21.63%), Postives = 145/319 (45.45%), Query Frame = -3 
Query:   85 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANN---LIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHG 1014
            P+D + +E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   + E+ G+ D +      +LK   GL  L+ R+++ AA  FL A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  +  G
Sbjct:  121 PLDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKCAAGLAELAARKYKQAAKCFLLASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMHKMAAAFNTTVAALEDELTQLILEGLINARIDSHSKILYARDVDQRSTTFEKSLLMG 439
[Close]
BLAST of SMED30004578 vs. UniProt/SwissProt
Match: sp|Q15008|PSMD6_HUMAN (26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1)

HSP 1 Score: 479.945 bits (1234), Expect = 4.928e-168
Identity = 231/393 (58.78%), Postives = 302/393 (76.84%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAF-----QYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP+EN EEEGL K PDLR+ Q  F     +++ D +    ++D+L+  +  N+M PYYE + + L+  +D  LL KMK ANED+LK LD  +++AE+N G++E+R+AM+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV  SMI+L+R DLR+KV++G+EILEVLHSLP+V+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRI AY Q LESY SL++  M++ FG+ +EF+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:    1 MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAA----VRDELMAAVRDNNMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 389
[Close]
BLAST of SMED30004578 vs. UniProt/SwissProt
Match: sp|Q3T0B2|PSMD6_BOVIN (26S proteasome non-ATPase regulatory subunit 6 OS=Bos taurus OX=9913 GN=PSMD6 PE=2 SV=1)

HSP 1 Score: 477.248 bits (1227), Expect = 5.390e-167
Identity = 230/393 (58.52%), Postives = 300/393 (76.34%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAF-----QYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP+EN EEEGL K PDLR+ Q  F     +++ D +    ++D+L+  +  N+M PYYE + + L   MD  LL KMK ANED+LK LD  +++AE+N G++E+R+AM+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV  SMI+L+R DLR+KV++G+EILEVLHSLP+V+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRI AY Q LESY SL++  M++ FG+ +EF+D ELSRFI+ GRL CKID+VN ++ET RPDS N QYQ  IK G +LLNR+QKLSRVIN+
Sbjct:    1 MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAA----VRDELMAAVRDNNMAPYYEALCKSLEWQMDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRRTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAIVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEVVETNRPDSKNWQYQETIKKGGLLLNRVQKLSRVINM 389
[Close]
BLAST of SMED30004578 vs. UniProt/SwissProt
Match: sp|Q99JI4|PSMD6_MOUSE (26S proteasome non-ATPase regulatory subunit 6 OS=Mus musculus OX=10090 GN=Psmd6 PE=1 SV=1)

HSP 1 Score: 476.863 bits (1226), Expect = 8.344e-167
Identity = 229/393 (58.27%), Postives = 302/393 (76.84%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAF-----QYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP+EN EEEGL K PDLR+ Q  F     +++ D +    ++++L+  +  N+M PYYE + + L+  MD  LL KMK ANE++LK LD  +++AE+N G++E+R+AM+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV  SMI+L+R DLR+KV++G+EILEVLHSLP+V+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRI AY Q LESY SL++  M++ FG+ ++F+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:    1 MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAA----VREELMAAVRENNMAPYYEALCKSLDWQMDVDLLSKMKKANEEELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCQIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAIVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVDFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 389
[Close]
BLAST of SMED30004578 vs. UniProt/SwissProt
Match: sp|Q9V3G7|PSMD6_DROME (26S proteasome non-ATPase regulatory subunit 6 OS=Drosophila melanogaster OX=7227 GN=Rpn7 PE=2 SV=1)

HSP 1 Score: 452.595 bits (1163), Expect = 2.632e-157
Identity = 219/393 (55.73%), Postives = 292/393 (74.30%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAF-----QYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP EN EE+GLEK P+L L Q  F     +YK D +    +K KL+E I   +M P+YE I  EL   +D  LL +MK  N  ++++LD  I++AE+N G+ EVREA + K+ YL +IG +  A   F    EKT+ LG+RLD+ FHLIR+G F+ D  LIT+NI+KA  LIEEGGDWDRRNRLKVY+G+YS+++R+F+ AA  FL+ V+TFTSYELMDY TF+ YTV  +MI+L R++LRDKV++GSEI EVLH LP VK+FL SLY C+Y +F+ +LAG+E  +++D  + PHYRYY+REMRIL Y Q LESY SL++  M++ FG+++E++D EL+RFI+ GRL  K+D+V GI+ET RPD+ N QYQ+ IK GD+LLNRIQKLSRVINI
Sbjct:    1 MPAENLEEQGLEKNPNLELAQTKFLLTLAEYKQDAA----LKAKLLEAIRTENMAPWYEHICSELGWTVDKDLLARMKENNRVEVEQLDAAIEDAEKNLGEMEVREANLKKSEYLCRIGDKAAAETAFRKTYEKTVSLGHRLDIVFHLIRLGLFYLDHDLITRNIDKAKYLIEEGGDWDRRNRLKVYQGVYSVAVRDFKAAATFFLDTVSTFTSYELMDYPTFVRYTVYVAMIALPRNELRDKVIKGSEIQEVLHGLPDVKQFLFSLYNCQYENFYVHLAGVEKQLRLDYLIHPHYRYYVREMRILGYTQLLESYRSLTLQYMAESFGVTVEYIDQELARFIAAGRLHAKVDRVGGIVETNRPDNKNWQYQATIKQGDLLLNRIQKLSRVINI 389
[Close]
BLAST of SMED30004578 vs. UniProt/SwissProt
Match: sp|Q93Y35|PSMD6_ARATH (26S proteasome non-ATPase regulatory subunit 6 homolog OS=Arabidopsis thaliana OX=3702 GN=RPN7 PE=1 SV=1)

HSP 1 Score: 392.504 bits (1007), Expect = 1.196e-133
Identity = 184/356 (51.69%), Postives = 262/356 (73.60%), Query Frame = -3 
Query:   37 KHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1104
            K Q+K ++++ I  + M P YE +     + +D SLLE M++ANE++LK+LD  I +AEEN G++EVREA +AKA Y  +I  +EKAL+Q  L   KT+ +G ++D+ F+ +++ FF+ D  L++K+I+KA  L EEGGDW+R+NRLKVY+GLY +S R F+ AA+ FL++++TFT+YE+  Y+TFI YTVL S+I+L R  L+ KVV   EIL VL  +P + EFL SLYEC+Y  FF   AG+   +K D YL PH+R+Y+RE+R + Y Q LESY S++V  M+K FG+S++F+D ELSRFI+ G+L CKID+V G++ET RPD+ N+ YQ+ IK GD LLNRIQKLSRVI++
Sbjct:   32 KVQLKSEVLDFIRSHGMAPLYETLIASSVLDLDQSLLESMRAANEEELKKLDEKIADAEENLGESEVREAHLAKALYFIRISDKEKALEQLKLTEGKTVAVGQKMDVVFYTLQLAFFYMDFDLVSKSIDKAKKLFEEGGDWERKNRLKVYEGLYCMSTRNFKKAASLFLDSISTFTTYEIFPYETFIFYTVLTSIITLDRVSLKQKVVDAPEILTVLGKIPFLSEFLNSLYECQYKAFFSAFAGMAVQIKYDRYLYPHFRFYMREVRTVVYSQFLESYKSVTVEAMAKAFGVSVDFIDQELSRFIAAGKLHCKIDKVAGVLETNRPDAKNALYQATIKQGDFLLNRIQKLSRVIDL 387
[Close]
BLAST of SMED30004578 vs. TrEMBL
Match: A0A5K3EF25 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 560.836 bits (1444), Expect = 0.000e+0
Identity = 261/391 (66.75%), Postives = 326/391 (83.38%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAFQY---KCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MPVE+FE+EGLE+IPDLRL QW FQ    +     K  + ++++ VI  ++M P+Y+I+  +L +  D  L+ +M+SANE K+KEL+ NIK AEE+ G+TE+R+AMIAKAHYLSKIG +  AL QF  IL+KT++ G RLD+TFHLIR+GFFFND+ LIT NIEKAN+LIEEGGDWDRRNRLKVY+GL+SLSIR+F+ +A HFL+AVATFTSYELMDYK+FIIYTVL SMI+LKR DLR KV+ GSEI EVLHSLP+VKE+L SLYECRY+DFF YLA +E +M  D YL  H RYY+REMRI AY QHL+SY+SLS+ +M+  FG+++ FLD ELSRFI+NGR+ACKID+V GI+ETTRPD+VNSQYQ++IKHGD+LLNRIQKLS+VINI
Sbjct:    1 MPVESFEDEGLERIPDLRLSQWLFQASLSRTSADKKADLVEQIMTVIQADNMTPFYKIVCDQLQLKEDEDLINQMQSANEAKMKELEENIKKAEESEGETEIRDAMIAKAHYLSKIGNKADALTQFRTILDKTVLPGCRLDITFHLIRMGFFFNDKDLITTNIEKANSLIEEGGDWDRRNRLKVYRGLHSLSIRDFDASAKHFLDAVATFTSYELMDYKSFIIYTVLTSMIALKRQDLRSKVIMGSEIQEVLHSLPAVKEYLTSLYECRYADFFLYLAAVEQFMHSDRYLAAHARYYVREMRISAYCQHLDSYSSLSLESMATTFGVTVGFLDAELSRFIANGRIACKIDKVAGIVETTRPDNVNSQYQAIIKHGDVLLNRIQKLSQVINI 391
[Close]
BLAST of SMED30004578 vs. TrEMBL
Match: A0A0R3S9W3 (PCI domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS1081 PE=4 SV=2)

HSP 1 Score: 558.525 bits (1438), Expect = 0.000e+0
Identity = 262/391 (67.01%), Postives = 328/391 (83.89%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAFQYKCD---VSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MPVE FEEEGLE+IPDLRL QW F    D     +K  +   ++++I   +M P+Y+++ ++L++  D +L+  M+ ANE+KLKELD NI+ AEE+ G+TE+REAMIAKAHYLSKIG + +AL QF  IL+KT++ G RLD+TFHLIR+GFF+NDR LIT NIEKAN+LIEEGGDWDRRNRLKVY+GL+SLSIR+F++AA HFL+AVATFTSYELMDYK FI+YTVL S+ISLKR DLR KVV GSEI EVLHSLP+VKE+LMSL+ECRY+DFF YLAG+E +M  D YL  H RYY+REMRI AY QHL+SY+SLS+ +M+  FG+++ FLD ELSRFI+NGR+ACKID+V GI+ETTRPD+VNSQYQ++IKHGD+LLNRIQKLS+VIN+
Sbjct:    1 MPVELFEEEGLERIPDLRLSQWLFLATLDRPSTKSKDALVKTMMDIIKTENMTPFYKLVCKQLHLFEDQALVATMQKANEEKLKELDENIQKAEESDGETEIREAMIAKAHYLSKIGNKAEALSQFRTILDKTVLPGCRLDITFHLIRMGFFWNDRDLITSNIEKANSLIEEGGDWDRRNRLKVYRGLHSLSIRDFDSAAKHFLDAVATFTSYELMDYKNFIVYTVLTSLISLKRQDLRLKVVMGSEIQEVLHSLPAVKEYLMSLFECRYADFFLYLAGVEQFMHSDRYLAAHARYYVREMRIRAYTQHLDSYSSLSLESMAATFGVTMNFLDAELSRFIANGRIACKIDKVTGIVETTRPDNVNSQYQAMIKHGDVLLNRIQKLSQVINM 391
[Close]
BLAST of SMED30004578 vs. TrEMBL
Match: A0A0X3P5F7 (26S proteasome non-ATPase regulatory subunit 6 OS=Schistocephalus solidus OX=70667 GN=PSMD6 PE=4 SV=1)

HSP 1 Score: 556.599 bits (1433), Expect = 0.000e+0
Identity = 257/391 (65.73%), Postives = 332/391 (84.91%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAFQYKCD---VSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP+E+FEEEGLE+IPDLRL QW FQ   D    + +  +  +++ V+   +M PYY+ + ++L++ +D +L+++M++AN +KLKELD  IKNAE+N G+TE+RE+M+AKAHYLSKIG + +AL QF L+L+KT++ G RLD+ FHLIRIGFFFND +L+TKNI+KAN+LIEEGGDWDRRNRLKVY+GL+SLS+R+F++AA HFL+AVATFTSYELMDYK+FIIYTVL +MI+LKR DLR KV+ GSE+ EVLHSLP+VKE+L SL+ECRY+DFF YLA +E YM  D Y  PH R+Y+REMRI AY QHL+SY+SLS+ +M+  FG+++ FLD ELSRFI+NGRLACKID+V GI+ETTRPD+VNSQYQ++IKHGDILLNRIQKLS+VINI
Sbjct:    1 MPLESFEEEGLERIPDLRLSQWLFQASLDRTPAAKRASLITEIMCVVKEENMTPYYKHVCKQLHLNVDQALVDQMQAANVEKLKELDEKIKNAEKNEGETEIRESMLAKAHYLSKIGNKAEALAQFRLLLDKTVLPGCRLDMIFHLIRIGFFFNDGELVTKNIDKANSLIEEGGDWDRRNRLKVYRGLHSLSVRDFDSAAKHFLDAVATFTSYELMDYKSFIIYTVLTAMIALKRQDLRSKVINGSEVQEVLHSLPAVKEYLDSLFECRYADFFLYLAAVEQYMHSDRYFAPHARFYVREMRIRAYSQHLDSYSSLSLESMAATFGVTMPFLDTELSRFIANGRLACKIDKVAGIVETTRPDNVNSQYQAMIKHGDILLNRIQKLSQVINI 391
[Close]
BLAST of SMED30004578 vs. TrEMBL
Match: A0A0R3W0Y2 (PCI domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS3360 PE=4 SV=1)

HSP 1 Score: 555.058 bits (1429), Expect = 0.000e+0
Identity = 261/388 (67.27%), Postives = 325/388 (83.76%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP E+FEEEGLE+IPDLRL QW FQ      N+  +K     V ++ DM P+Y+II ++L++     ++ +M+ AN ++LK LD NIKNAEE+ G+TE+REAMIAKAHYLSKIG++  AL QF  IL+KT++ G RLD+TFHLIR+GFF+NDR LIT NIEKAN+LIEEGGDWDRRNRLKVY+GL+SLSIR+F+ +A HFL+AVATFTSYELMDYK+FIIYTVL SMI+LKR DLR KV+ GSEI EVLHSLP+V+E+LMSL+ECRY+DFF YLAG+E +M  D YL  H RYY+REMRI AY QHL+SY+SLS+ +M+  FG+++ FLD ELSRFI+NGR+ACKID+V GI+ETTRPD+VNSQYQ++IKHGD+LLNRIQKLS+VINI
Sbjct:    1 MPPESFEEEGLERIPDLRLSQWLFQASL---NRTTVKSSC--VFSILDMTPFYKIICKQLHLLESQQVIGEMQKANHERLKALDENIKNAEESDGETEIREAMIAKAHYLSKIGSKTDALAQFRAILDKTVLPGCRLDITFHLIRMGFFYNDRDLITTNIEKANSLIEEGGDWDRRNRLKVYRGLHSLSIRDFDASAKHFLDAVATFTSYELMDYKSFIIYTVLTSMIALKRQDLRAKVIMGSEIQEVLHSLPAVREYLMSLFECRYADFFLYLAGVEQFMHSDRYLAAHARYYVREMRIRAYAQHLDSYSSLSLESMAATFGVTMSFLDAELSRFIANGRIACKIDKVTGIVETTRPDNVNSQYQAMIKHGDVLLNRIQKLSQVINI 383
[Close]
BLAST of SMED30004578 vs. TrEMBL
Match: U6IYU3 (26S proteasome non-ATPase regulatory subunit 6 OS=Echinococcus granulosus OX=6210 GN=EGR_02124 PE=4 SV=1)

HSP 1 Score: 554.673 bits (1428), Expect = 0.000e+0
Identity = 258/391 (65.98%), Postives = 329/391 (84.14%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAFQY---KCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP E+FEEEGLE+IPDLRL QW F+    +  V ++ ++ + +++V+   +M P+Y+I+ ++L++     L+ +M+ AN+D+L+ELD NIK AEE+ G+TE+REAMIAKAHYLSKIG +  AL QF  IL+KT++ G RLD+TFHLIR+GFF+NDR LIT NIEKAN+LIEEGGDWDRRNRLKVY+GL+SLSIR+F  +A HFL+AVATFTSYELMDYK+FIIYTVL SMI+LKR DLR KV+ GSEI EVLHSLP+V+E+LMSL+ECRY+DFF YLAG+E +M  D YL  H RYY+REMRI AY QHL+SY+SLS+ +M+  FG+++ FLD ELSRFI+NGR+ACKID+V GI+ETTRPD+VNSQYQ++IKHGD+LLNRIQKLS+VINI
Sbjct:    1 MPAESFEEEGLERIPDLRLSQWLFEASLNRTTVKSRSRLVNLIMDVVRSENMTPFYKIVCKQLHLLDSQQLMGEMQRANDDRLEELDENIKKAEESDGETEIREAMIAKAHYLSKIGNKMDALAQFRAILDKTVLPGCRLDITFHLIRMGFFYNDRDLITTNIEKANSLIEEGGDWDRRNRLKVYRGLHSLSIRDFNASAKHFLDAVATFTSYELMDYKSFIIYTVLTSMIALKRQDLRAKVIMGSEIQEVLHSLPAVREYLMSLFECRYADFFLYLAGVEQFMHSDRYLAAHARYYVREMRIRAYTQHLDSYSSLSLESMAATFGVTMSFLDAELSRFIANGRIACKIDKVTGIVETTRPDNVNSQYQAIIKHGDVLLNRIQKLSQVINI 391
[Close]
BLAST of SMED30004578 vs. Ensembl Cavefish
Match: psmd6 (proteasome 26S subunit, non-ATPase 6 [Source:ZFIN;Acc:ZDB-GENE-040426-1038])

HSP 1 Score: 459.914 bits (1182), Expect = 1.259e-161
Identity = 219/356 (61.52%), Postives = 281/356 (78.93%), Query Frame = -3 
Query:   37 KHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1104
            +H  KD  + ++  +DM PYYE + +EL  P+D+ LL KMK ANED+LK LD+ +++AE+N G++E+R+AM+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV   MI+LKR DLR+KV++G+EILEVLHSLP V+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRILAY Q LESY SL++  M++ FG+S EF+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:    4 QHTQKDIFL-ILCFSDMAPYYEALCKELKWPVDSDLLGKMKKANEDELKRLDDVLEDAEKNLGESEIRDAMMAKAEYLIRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVCMIALKRPDLREKVIKGAEILEVLHSLPDVRQYLFSLYECRYSIFFQSLARVEQDMKRDWLFAPHYRYYVREMRILAYSQLLESYRSLTLGYMAEAFGVSTEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 358
[Close]
BLAST of SMED30004578 vs. Ensembl Cavefish
Match: gps1 (G protein pathway suppressor 1 [Source:NCBI gene;Acc:103026457])

HSP 1 Score: 92.4337 bits (228), Expect = 6.577e-20
Identity = 70/319 (21.94%), Postives = 147/319 (46.08%), Query Frame = -3 
Query:   85 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANN---LIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHG 1014
            P+D +  E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   + E+ G+ D +N     +LK   GL  L+ R+++ AA  FL+A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  ++ G
Sbjct:  142 PLDTAWAESTRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQNQSVLTKLKCAAGLAELASRKYKPAAKCFLQASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMNKMAIAFNTTVAALEDELTQLILEGLINARIDSHSKILYARDVDQRSTTFEKSLQMG 460
[Close]
BLAST of SMED30004578 vs. Ensembl Cavefish
Match: gps1 (G protein pathway suppressor 1 [Source:NCBI gene;Acc:103026457])

HSP 1 Score: 92.4337 bits (228), Expect = 6.952e-20
Identity = 71/329 (21.58%), Postives = 150/329 (45.59%), Query Frame = -3 
Query:   55 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANN---LIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKL 1014
            P+D +  E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   + E+ G+ D +N     +LK   GL  L+ R+++ AA  FL+A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  ++ G     R + +
Sbjct:  121 PLDTAWAESTRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQNQSVLTKLKCAAGLAELASRKYKPAAKCFLQASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMNKMAIAFNTTVAALEDELTQLILEGLINARIDSHSKILYARDVDQRSTTFEKSLQMGKEFQRRAKAM 449
[Close]
BLAST of SMED30004578 vs. Ensembl Cavefish
Match: gps1 (G protein pathway suppressor 1 [Source:NCBI gene;Acc:103026457])

HSP 1 Score: 92.4337 bits (228), Expect = 7.308e-20
Identity = 70/319 (21.94%), Postives = 147/319 (46.08%), Query Frame = -3 
Query:   85 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANN---LIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHG 1014
            P+D +  E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   + E+ G+ D +N     +LK   GL  L+ R+++ AA  FL+A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  ++ G
Sbjct:  179 PLDTAWAESTRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQNQSVLTKLKCAAGLAELASRKYKPAAKCFLQASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMNKMAIAFNTTVAALEDELTQLILEGLINARIDSHSKILYARDVDQRSTTFEKSLQMG 497
[Close]
BLAST of SMED30004578 vs. Ensembl Cavefish
Match: gps1 (G protein pathway suppressor 1 [Source:NCBI gene;Acc:103026457])

HSP 1 Score: 90.8929 bits (224), Expect = 2.640e-19
Identity = 67/294 (22.79%), Postives = 136/294 (46.26%), Query Frame = -3 
Query:  160 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANN---LIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKID 1014
            P+D +  E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   + E+ G+ D +N     +LK   GL  L+ R+++ AA  FL+A      + EL+      +Y  L ++ +  R +L+  V+  S     L   P V++ +   YE +Y+   + L  +++ + +D YL PH R    ++R  A  Q+   Y S  +  M+  F  ++  L++EL++ I  G +  +ID
Sbjct:  179 PLDTAWAESTRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQNQSVLTKLKCAAGLAELASRKYKPAAKCFLQASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMNKMAIAFNTTVAALEDELTQLILEGLINARID 472
[Close]
BLAST of SMED30004578 vs. Ensembl Sea Lamprey
Match: psmd6 (proteasome 26S subunit, non-ATPase 6 [Source:ZFIN;Acc:ZDB-GENE-040426-1038])

HSP 1 Score: 476.093 bits (1224), Expect = 3.865e-168
Identity = 223/389 (57.33%), Postives = 299/389 (76.86%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKHQ-IKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP+EN EEEGL K PDL++ QW F    D     + +K +L++ I  +DM P+YE + ++L    D  LL +M++ANE +L  LD  +++AE N G++E+R+AM+A+A +LS+IG +E +L  F    EKT+ LG+RLD+ F+LIRIG F+ D  LIT+NI+KA +LIEEGGDWDRRNRLKVY+G+Y L+IR+F+ AA  FL+ V+TFTSYELMDY+TF+ +TV  SMI+L+R DLR+KV++G+EILEVLH LP+V+++L SLYEC Y+ FF+ LA +E  MK D    PHY+YY+REMRILAY Q LESY SL++  M++ FG+S+EF+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:    1 MPIENLEEEGLPKNPDLQIAQWKFLLSLDDHRGDEAVKTQLMDAIKRHDMAPFYEEVCRDLKWRPDAPLLARMRAANEAELARLDAALEDAERNLGESEIRDAMLARAEHLSRIGDKESSLTAFRKTFEKTVALGHRLDIVFYLIRIGLFYLDNDLITRNIDKAKSLIEEGGDWDRRNRLKVYQGVYLLAIRDFKGAAELFLDTVSTFTSYELMDYRTFVTHTVYVSMIALERPDLREKVIKGAEILEVLHGLPAVRQYLFSLYECHYASFFQSLAKVEQEMKADRLFAPHYQYYVREMRILAYSQLLESYRSLTLSYMAQAFGVSVEFVDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 389
[Close]
BLAST of SMED30004578 vs. Ensembl Yeast
Match: RPN7 (Essential non-ATPase regulatory subunit of the 26S proteasome; similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits [Source:SGD;Acc:S000006312])

HSP 1 Score: 251.906 bits (642), Expect = 4.716e-80
Identity = 139/406 (34.24%), Postives = 231/406 (56.90%), Query Frame = -3 
Query:   37 KIPDLRLPQWAF---QYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQE------------------LN--IPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVR-EAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHS---LPSVKEFLMSLYECRYSDFFRYLAGIENYMKI---DSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1164
            ++P+  + + AF   Q K  +  + +  + ++  I   +M PYY+ + +E                  LN  I  D  L  ++   NE K+KEL+  I+  EE+      + +A I    Y ++IG ++ A       L K +  G ++D+   + R+GFF+ND+  + + +E  N++IE+GGDW+RRNR K Y G++ L++R F+ AA   ++++ATFTS EL  Y++   Y  +  + +L+R+DL+ KV+   E+L ++ +   L S+    +SLY   Y+ +F YL  +E Y  +     YL  H  +++REMR   Y Q LESY +LS+ +M+  FG+S+ FLDN+L +FI N +L C ID+VNGI+ET RPD+ N+QY  ++K GD LL ++QK    + +
Sbjct:   20 RVPNYEVSEKAFLLTQSKVSIEQRKEAAEFVLAKIKEEEMAPYYKYLCEEYLVNNGQSDLEHDEKSDSLNEWIKFDQELYNELCKKNESKIKELNEKIQKLEEDDEGELEQAQAWINLGEYYAQIGDKDNAEKTLGKSLSKAISTGAKIDVMLTIARLGFFYNDQLYVKEKLEAVNSMIEKGGDWERRNRYKTYYGIHCLAVRNFKEAAKLLVDSLATFTSIELTSYESIATYASVTGLFTLERTDLKSKVIDSPELLSLISTTAALQSISSLTISLYASDYASYFPYL--LETYANVLIPCKYLNRHADFFVREMRRKVYAQLLESYKTLSLKSMASAFGVSVAFLDNDLGKFIPNKQLNCVIDRVNGIVETNRPDNKNAQYHLLVKQGDGLLTKLQKYGAAVRL 423
[Close]
BLAST of SMED30004578 vs. Ensembl Nematostella
Match: EDO30816 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZN8])

HSP 1 Score: 472.626 bits (1215), Expect = 1.530e-166
Identity = 229/389 (58.87%), Postives = 291/389 (74.81%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAFQ-YKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP+EN EEEGL K P+L L Q  F     D  +K + K  L++V+   DM P+YE +  E   P+D  LLEKMK  N +KL+ELD  +K+AEEN G+TE+R+A+ A+  YL  IG +E A+  F    +K + LGY+LD+ F+ IRIG F+ D  +ITKNI KA  LIEEGGDWDRRNRLKVY+G+Y +SIR+F+ AA++FLE+++TFTSYELMDY+TF+  T+L SMISL+R DLR KV+ G+EILEVLH LP +K+FL+SLYEC YS+FF  LA +E  +K D  + PHYRYY+REMRILAY Q LESY SL++  M+  FG+S EF+D ELSRFI+ GRL CKID+V GI+ET RPD  N QYQ+ IK GD+LLNRIQKLSRVINI
Sbjct:    1 MPIENLEEEGLPKNPNLELAQLRFVLVNPDGVDKEKAKKMLLDVVKAKDMAPFYEELCAEFKWPVDKPLLEKMKQKNTEKLEELDKTLKDAEENLGETEIRDALFARGEYLCSIGDKEGAITAFRKSYDKAVALGYKLDILFYRIRIGLFYLDNDMITKNISKAKELIEEGGDWDRRNRLKVYQGIYFMSIRDFKAAASNFLESISTFTSYELMDYQTFVTNTILTSMISLERVDLRKKVINGAEILEVLHQLPVIKQFLVSLYECHYSEFFTALAQVEQMLKQDRLMSPHYRYYVREMRILAYTQLLESYRSLTLQYMANAFGVSEEFIDKELSRFIAAGRLNCKIDKVGGIVETNRPDHKNWQYQATIKQGDLLLNRIQKLSRVINI 389
[Close]
BLAST of SMED30004578 vs. Ensembl Nematostella
Match: EDO36846 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHI2])

HSP 1 Score: 91.2781 bits (225), Expect = 5.378e-20
Identity = 69/310 (22.26%), Postives = 139/310 (44.84%), Query Frame = -3 
Query:   55 KLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIE-----EGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKL 966
            KL++LD ++KN + N     +R        +  + G    AL  ++   +      + +++  ++I++     +   +   + KA N  E      G       +LK   GL  L+ R++++AA +FL+A        EL+      IY  L ++ S  R +L+ KV+  S     L   P +++ L   +E +Y+   + L  +++   +D YL  H      ++R  A  Q+   Y S  +  M+  F  ++  L++ELS+ I +G++  +ID  N ++     D  ++ ++  ++ G     R + L
Sbjct:  127 KLEKLDTDLKNYKSNSIKESIRRGHDDLGDHYFECGDLNNALKCYSRSRDYCTSAKHVVNMCLNVIKVSIHMGNWSHVLNYVNKAENTTELTEKERGSSQTTLTKLKCAAGLAELATRKYKSAARYFLQASFDHCDCPELLSSNNVAIYGGLCALASFDRQELQKKVLSSSSFKLFLELEPQLRDVLYKFHESQYATCLKLLDDLKDNFMLDMYLAQHITKLYSQIRKRALIQYFSPYVSADMSKMAHAFNTTVHQLEDELSQLILDGQINARIDSHNKVLYARDVDQRSTTFEKALEMGKEYQKRTKAL 436
[Close]
BLAST of SMED30004578 vs. Ensembl Medaka
Match: psmd6 (proteasome 26S subunit, non-ATPase 6 [Source:NCBI gene;Acc:101172070])

HSP 1 Score: 479.945 bits (1234), Expect = 4.822e-169
Identity = 230/389 (59.13%), Postives = 298/389 (76.61%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKHQ-IKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MP+EN EEEGL K PDLR+ Q  F    +   +   +K +L++ I  N+M PYYE + +EL   +D  LL KMK AN+++LK LD+ +++AE+N G++E+R+ M+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV   MI+L+R DLR+KV++G+EILEVLHSLPSV+++L SLYECRYS FF+ LA +E  MK D    PHYRYY+REMRI AY Q LESY SL++  M++ FG+S EF+D ELSRFI+ GRL CKID+VN I+ET RPDS N QYQ  IK GD+LLNR+QKLSRVIN+
Sbjct:    1 MPLENLEEEGLPKNPDLRIAQLKFLLTMEAHRQDANVKTELMDAIKANNMAPYYEALCKELKWQLDTELLSKMKKANDEELKRLDDVLEDAEKNLGESEIRDVMMAKAEYLIRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDSDLITRNSEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVCMIALERPDLREKVIKGAEILEVLHSLPSVRQYLFSLYECRYSAFFQSLAMVEQEMKKDWLFAPHYRYYVREMRIQAYSQLLESYRSLTLGYMAEAFGVSTEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 389
[Close]
BLAST of SMED30004578 vs. Ensembl Medaka
Match: psmd6 (proteasome 26S subunit, non-ATPase 6 [Source:NCBI gene;Acc:101172070])

HSP 1 Score: 312.768 bits (800), Expect = 2.114e-103
Identity = 160/317 (50.47%), Postives = 215/317 (67.82%), Query Frame = -3 
Query:  331 MPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKHQ-IKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDK--------------------------VVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPH 1200
            MP+EN EEEGL K PDLR+ Q  F    +   +   +K +L++ I  N+M PYYE + +EL   +D  LL KMK AN+++LK LD+ +++AE+N G++E+R+ M+AKA YL +IG +E AL  F    +KT+ LG+RLD+ F+L+RIG F+ D  LIT+N EKA +LIEEGGDWDRRNRLKVY+GLY ++IR+F+ AA  FL+ V+TFTSYELMDYKTF+ YTV   MI+L+R DLR+K                          V++G+EILEVLHSLPSV+++L SLYECRYS FF+ L       K   YLC +
Sbjct:    1 MPLENLEEEGLPKNPDLRIAQLKFLLTMEAHRQDANVKTELMDAIKANNMAPYYEALCKELKWQLDTELLSKMKKANDEELKRLDDVLEDAEKNLGESEIRDVMMAKAEYLIRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDSDLITRNSEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVCMIALERPDLREKVGKIFFYCTLFCCSCEAVVLINFSLQVIKGAEILEVLHSLPSVRQYLFSLYECRYSAFFQSLG------KGTFYLCKY 311
[Close]
BLAST of SMED30004578 vs. Ensembl Medaka
Match: gps1 (G protein pathway suppressor 1 [Source:NCBI gene;Acc:101160817])

HSP 1 Score: 91.2781 bits (225), Expect = 1.882e-19
Identity = 68/324 (20.99%), Postives = 148/324 (45.68%), Query Frame = -3 
Query:   85 PMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANN---LIEEGGDWDRRN-----RLKVYKGLYSLSIREFENAANHFLEA------VATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHG 1014
            P+D++  E  +     KL++LD ++KN + N     +R        +    G    AL  ++   +      + +++  ++I++  +  +   +   + KA +   + E+ G+ D +N     +LK   GL  L+ R+++ AA  FL+A         F   +L+      +Y  L ++ +  R +L+  V+  S     L   P +++ +   YE +Y+   + L  +++ + +D YL PH +    ++R  A  Q+   Y S  +  M++ F  ++  L++EL++ I  G +  +ID  + I+     D  ++ ++  +  G
Sbjct:  121 PLDSAWAESTRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVNKAESTPEIAEQRGERDGQNQAVLTKLKCAAGLAELASRKYKPAAKCFLQASFDHCDCPEFVFLQLLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQIRDIIFKFYESKYASCLKLLDDMKDNLLLDMYLAPHIKILYSQIRNRALIQYFSPYVSADMTKMAQAFNTTVAALEDELTQLILEGLVNARIDSHSKILYARDVDQRSTTFEKSLHMG 444
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BLAST of SMED30004578 vs. Planmine SMEST
Match: SMESG000066093.1 (SMESG000066093.1)

HSP 1 Score: 791.956 bits (2044), Expect = 0.000e+0
Identity = 387/388 (99.74%), Postives = 387/388 (99.74%), Query Frame = -3 
Query:   37 MPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 1200
            MPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKS NEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI
Sbjct:    1 MPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSTNEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI 388
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BLAST of SMED30004578 vs. Planmine SMEST
Match: SMESG000066079.1 (SMESG000066079.1)

HSP 1 Score: 784.252 bits (2024), Expect = 0.000e+0
Identity = 383/386 (99.22%), Postives = 385/386 (99.74%), Query Frame = -3 
Query:   43 MPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVI 1200
            MPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLS ++
Sbjct:    1 MPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKHQIKDKLIEVITLNDMGPYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHFLEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSELL 386
[Close]
BLAST of SMED30004578 vs. Planmine SMEST
Match: SMESG000027211.1 (SMESG000027211.1)

HSP 1 Score: 87.4261 bits (215), Expect = 2.819e-18
Identity = 74/343 (21.57%), Postives = 143/343 (41.69%), Query Frame = -3 
Query:  103 IPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEE-------------------GGDW--------------DRRNRLK----VYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQ 1017
            +  D+  ++K +  +   + +LD ++KN + N+    +R      A    K G    A   +    +      + L + F++I++  +    + ++  +++A  L+E                     G W              D R ++K       GL  +  R F  AA  FL+A   + S+  ++      +Y  + S+ +  R+ L+  V++ S     L + P++++ L + Y  +Y++  + +A I+N + +D YL  H  Y  RE+R  A  Q+   Y    +  ++  F  S+  L  EL   IS G+L  KID  N ++  T     N  +Q
Sbjct:  140 LEFDSDWVDKTRRQSNQTIDQLDTDLKNYKANNMAESIRRGCDELASVHMKTGDLLSANKNYTRSRDYCKTDMHELMMCFNVIKVSIYLTHWRHVSSYVDRAETLLENITNGCSSTGSQNRSISDEVSGSWKQSSNTEKVTSDQKDNRQKMKALLHCVVGLVEMYERNFAAAARAFLQADHDYVSFNSILTANDVALYGTICSLATFDRNALKSMVIQNSNFKMFLENEPTLRDILHNFYNFQYAECLKGMAQIKNQLLLDIYLADHVEYLYREIRNRALCQYFSPYQCADLNKIATCFNTSVPELLQELKPLISTGQLKAKIDSHNNLLLVTSISQQNQVFQ 482
[Close]
BLAST of SMED30004578 vs. Planmine SMEST
Match: SMESG000027211.1 (SMESG000027211.1)

HSP 1 Score: 87.0409 bits (214), Expect = 2.877e-18
Identity = 74/343 (21.57%), Postives = 143/343 (41.69%), Query Frame = -3 
Query:  103 IPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVREAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFFNDRKLITKNIEKANNLIEE-------------------GGDW--------------DRRNRLK----VYKGLYSLSIREFENAANHFLEAVATFTSY-ELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLHSLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRILAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVNGIIETTRPDSVNSQYQ 1017
            +  D+  ++K +  +   + +LD ++KN + N+    +R      A    K G    A   +    +      + L + F++I++  +    + ++  +++A  L+E                     G W              D R ++K       GL  +  R F  AA  FL+A   + S+  ++      +Y  + S+ +  R+ L+  V++ S     L + P++++ L + Y  +Y++  + +A I+N + +D YL  H  Y  RE+R  A  Q+   Y    +  ++  F  S+  L  EL   IS G+L  KID  N ++  T     N  +Q
Sbjct:  134 LEFDSDWVDKTRRQSNQTIDQLDTDLKNYKANNMAESIRRGCDELASVHMKTGDLLSANKNYTRSRDYCKTDMHELMMCFNVIKVSIYLTHWRHVSSYVDRAETLLENITNGCSSTGSQNRSISDEVSGSWKQSSNTEKVTSDQKDNRQKMKALLHCVVGLVEMYERNFAAAARAFLQADHDYVSFNSILTANDVALYGTICSLATFDRNALKSMVIQNSNFKMFLENEPTLRDILHNFYNFQYAECLKGMAQIKNQLLLDIYLADHVEYLYREIRNRALCQYFSPYQCADLNKIATCFNTSVPELLQELKPLISTGQLKAKIDSHNNLLLVTSISQQNQVFQ 476
The following BLAST results are available for this feature:
BLAST of SMED30004578 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PSMD61.026e-16858.78proteasome 26S subunit, non-ATPase 6 [Source:HGNC ... [more]
PSMD66.936e-15851.79proteasome 26S subunit, non-ATPase 6 [Source:HGNC ... [more]
PSMD61.366e-15762.17proteasome 26S subunit, non-ATPase 6 [Source:HGNC ... [more]
PSMD62.073e-15762.17proteasome 26S subunit, non-ATPase 6 [Source:HGNC ... [more]
PSMD69.081e-6257.67proteasome 26S subunit, non-ATPase 6 [Source:HGNC ... [more]
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BLAST of SMED30004578 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rpn-72.922e-11845.9826S proteasome non-ATPase regulatory subunit 6 [S... [more]
csn-12.125e-824.63COP9 signalosome complex subunit 1 [Source:UniPro... [more]
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BLAST of SMED30004578 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Rpn72.625e-15855.73gene:FBgn0028688 transcript:FBtr0084294[more]
CSN1b4.903e-1924.27gene:FBgn0027057 transcript:FBtr0075074[more]
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BLAST of SMED30004578 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
psmd63.930e-17260.51proteasome 26S subunit, non-ATPase 6 [Source:ZFIN;... [more]
gps16.342e-2021.58G protein pathway suppressor 1 [Source:ZFIN;Acc:ZD... [more]
gps14.571e-1921.28G protein pathway suppressor 1 [Source:ZFIN;Acc:ZD... [more]
gps15.693e-1922.79G protein pathway suppressor 1 [Source:ZFIN;Acc:ZD... [more]
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BLAST of SMED30004578 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
psmd97.827e-16657.80proteasome 26S subunit, non-ATPase 9 [Source:Xenba... [more]
gps12.162e-1921.63G protein pathway suppressor 1 [Source:NCBI gene;A... [more]
gps11.458e-1822.67G protein pathway suppressor 1 [Source:NCBI gene;A... [more]
gps11.784e-1822.67G protein pathway suppressor 1 [Source:NCBI gene;A... [more]
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BLAST of SMED30004578 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Psmd61.193e-16758.27proteasome (prosome, macropain) 26S subunit, non-A... [more]
Psmd65.032e-7649.59proteasome (prosome, macropain) 26S subunit, non-A... [more]
Gps17.134e-1922.01G protein pathway suppressor 1 [Source:MGI Symbol;... [more]
Gps18.084e-1921.28G protein pathway suppressor 1 [Source:MGI Symbol;... [more]
Gps11.101e-1821.63G protein pathway suppressor 1 [Source:MGI Symbol;... [more]
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BLAST of SMED30004578 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q15008|PSMD6_HUMAN4.928e-16858.7826S proteasome non-ATPase regulatory subunit 6 OS=... [more]
sp|Q3T0B2|PSMD6_BOVIN5.390e-16758.5226S proteasome non-ATPase regulatory subunit 6 OS=... [more]
sp|Q99JI4|PSMD6_MOUSE8.344e-16758.2726S proteasome non-ATPase regulatory subunit 6 OS=... [more]
sp|Q9V3G7|PSMD6_DROME2.632e-15755.7326S proteasome non-ATPase regulatory subunit 6 OS=... [more]
sp|Q93Y35|PSMD6_ARATH1.196e-13351.6926S proteasome non-ATPase regulatory subunit 6 hom... [more]
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BLAST of SMED30004578 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5K3EF250.000e+066.75Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A0R3S9W30.000e+067.01PCI domain-containing protein OS=Hymenolepis dimin... [more]
A0A0X3P5F70.000e+065.7326S proteasome non-ATPase regulatory subunit 6 OS=... [more]
A0A0R3W0Y20.000e+067.27PCI domain-containing protein OS=Taenia asiatica O... [more]
U6IYU30.000e+065.9826S proteasome non-ATPase regulatory subunit 6 OS=... [more]
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BLAST of SMED30004578 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
psmd61.259e-16161.52proteasome 26S subunit, non-ATPase 6 [Source:ZFIN;... [more]
gps16.577e-2021.94G protein pathway suppressor 1 [Source:NCBI gene;A... [more]
gps16.952e-2021.58G protein pathway suppressor 1 [Source:NCBI gene;A... [more]
gps17.308e-2021.94G protein pathway suppressor 1 [Source:NCBI gene;A... [more]
gps12.640e-1922.79G protein pathway suppressor 1 [Source:NCBI gene;A... [more]
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BLAST of SMED30004578 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
psmd63.865e-16857.33proteasome 26S subunit, non-ATPase 6 [Source:ZFIN;... [more]
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BLAST of SMED30004578 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
RPN74.716e-8034.24Essential non-ATPase regulatory subunit of the 26S... [more]
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BLAST of SMED30004578 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO308161.530e-16658.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO368465.378e-2022.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SMED30004578 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
psmd64.822e-16959.13proteasome 26S subunit, non-ATPase 6 [Source:NCBI ... [more]
psmd62.114e-10350.47proteasome 26S subunit, non-ATPase 6 [Source:NCBI ... [more]
gps11.882e-1920.99G protein pathway suppressor 1 [Source:NCBI gene;A... [more]
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BLAST of SMED30004578 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000066093.10.000e+099.74SMESG000066093.1[more]
SMESG000066079.10.000e+099.22SMESG000066079.1[more]
SMESG000027211.12.819e-1821.57SMESG000027211.1[more]
SMESG000027211.12.877e-1821.57SMESG000027211.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004578 ID=SMED30004578|Name=SMED30004578|organism=Schmidtea mediterranea sexual|type=transcript|length=1283bp
TCTTTCAAATTAAAACATTTATTTTCACGAAACTCAAATATTAATAACTC
GGCTTAATTTTTGAATACGATTAAGCAGAATATCGCCGTGCTTAATAACC
GATTGATATTGGGAATTGACGCTATCGGGACGTGTTGTTTCAATTATTCC
GTTTACTTGATCTATCTTACAAGCCAACCTGCCATTAGAAATAAACCTAC
TCAACTCATTATCCAGAAATTCAATAGAAATCCCAAACAATTTGGACATA
TTTATAACACTAAGACTATTGTATGATTCCAAATGCTGTTTATAAGCCAA
AATTCGCATTTCTCGAATATAGTATCGATAATGAGGACATAAATATGAAT
CAATTTTCATGTAATTTTCTATTCCAGCTAAATATCTAAAGAAATCAGAA
TATCGACATTCATACAATGACATCAAAAACTCTTTAACACTAGGGAGACT
GTGTAAAACTTCAAGTATTTCCGATCCACGAACAACCTTATCTCTCAAAT
CAGATCGCTTCAATGAAATCATTGAGGCAAGAACAGTGTAAATAATAAAT
GTTTTATAATCCATCAATTCATAACTAGTAAAAGTTGCAACAGCTTCCAA
AAAATGATTTGCAGCATTCTCGAATTCTCGAATTGATAAACTATACAATC
CTTTGTAAACCTTCAATCGATTTCGCCTATCCCAATCGCCACCTTCTTCA
ATAAGATTATTAGCCTTTTCAATATTTTTTGTTATTAACTTTCTGTCATT
GAAAAAAAATCCAATTCGGATTAAATGGAAAGTTAGATCTAGCCTATATC
CCAACATTAGAGTTTTCTCCAAAATTAAATTAAATTGATCAAGAGCTTTT
TCCCTTGCACCAATTTTACTCAAATAGTGAGCCTTGGCAATCATCGCTTC
TCTAACTTCAGTATCTCCATGATTTTCTTCTGCATTTTTAATATTATTAT
CTAATTCTTTAAGTTTATCTTCATTTGCACTTTTCATTTTTTCCAATAAA
CTATTATCCATGGGTATATTAAGCTCCTGTGATATTATTTCATAATATGG
TCCCATATCATTTAATGTAATGACCTCAATTAATTTATCTTTAATTTGAT
GTTTGTTAGAAACATCACACTTATATTGAAAAGCCCATTGTGGTAGTCTT
AAATCGGGTATCTTTTCTAAGCCTTCTTCTTCAAAATTTTCAACAGGCAT
AATATTTAATTTTAAATTAATTTGCAAAATTTGAAATACAAGTATGAATA
AAGAGGTTTTAAACAAATGTTACCCGATTTAAG
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protein sequence of SMED30004578-orf-1

>SMED30004578-orf-1 ID=SMED30004578-orf-1|Name=SMED30004578-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=389bp
MPVENFEEEGLEKIPDLRLPQWAFQYKCDVSNKHQIKDKLIEVITLNDMG
PYYEIISQELNIPMDNSLLEKMKSANEDKLKELDNNIKNAEENHGDTEVR
EAMIAKAHYLSKIGAREKALDQFNLILEKTLMLGYRLDLTFHLIRIGFFF
NDRKLITKNIEKANNLIEEGGDWDRRNRLKVYKGLYSLSIREFENAANHF
LEAVATFTSYELMDYKTFIIYTVLASMISLKRSDLRDKVVRGSEILEVLH
SLPSVKEFLMSLYECRYSDFFRYLAGIENYMKIDSYLCPHYRYYIREMRI
LAYKQHLESYNSLSVINMSKLFGISIEFLDNELSRFISNGRLACKIDQVN
GIIETTRPDSVNSQYQSVIKHGDILLNRIQKLSRVINI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR035268PSMD6
IPR036390WH_DNA-bd_sf
IPR000717PCI_dom
IPR011991WHTH_DNA-bd_dom
IPR019585Rpn7/CSN1
IPR011990TPR-like_helical_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0030234enzyme regulator activity
GO:0005515protein binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 66..100
NoneNo IPR availableSMARTSM00753PINTcoord: 289..372
e-value: 2.1E-17
score: 73.8
NoneNo IPR availableGENE3DG3DSA:1.25.40.570coord: 24..308
e-value: 2.4E-39
score: 137.4
NoneNo IPR availablePANTHERPTHR1414526S PROTESOME SUBUNIT 6coord: 8..387
IPR000717Proteasome component (PCI) domainSMARTSM00088PINT_4coord: 289..372
e-value: 2.1E-17
score: 73.8
IPR000717Proteasome component (PCI) domainPFAMPF01399PCIcoord: 253..355
e-value: 2.5E-14
score: 53.6
IPR000717Proteasome component (PCI) domainPROSITEPS50250PCIcoord: 192..360
score: 22.332
IPR01958526S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1PFAMPF10602RPN7coord: 65..238
e-value: 6.7E-58
score: 195.2
IPR03526826S Proteasome non-ATPase regulatory subunit 6PANTHERPTHR14145:SF126S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6coord: 8..387
IPR036390Winged helix DNA-binding domain superfamilySUPERFAMILYSSF46785"Winged helix" DNA-binding domaincoord: 284..365