Metal transporter cnnm2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30004577 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Match: CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:HGNC Symbol;Acc:HGNC:103]) HSP 1 Score: 456.447 bits (1173), Expect = 7.646e-147 Identity = 260/577 (45.06%), Postives = 383/577 (66.38%), Query Frame = 2
Query: 500 SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG-ESLFKKAIEDMPDVEQLFNSHND--------------IGTVISNLTKNCF--FIPDFNLTAVTNLQYLKITAKHY----LFARMLSIWQNSD 2155
+ WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R++GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+VSTIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI+ +ILDF+TM+EI+ +G+TR+P++EGERSNI +L VKDLAF+DPDD P+ T+ FYN + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K++ R QDFS F ++ ++SPQL +A R LA+ V+ F ++ +L LL + N++ E + + + E ++++ K +Y +LILQGK E E + FEA F +G +L E+ +H+D +G+ + L + +IPD+++ A+++LQ++KI+ + Y + +RM Q+SD
Sbjct: 231 TTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPGENKSPPRPCGLNHSDSLSRSDRIDAVTPTLGSSNNQLNSSLLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSD 807
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Match: CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:HGNC Symbol;Acc:HGNC:103]) HSP 1 Score: 446.432 bits (1147), Expect = 7.427e-143 Identity = 261/599 (43.57%), Postives = 385/599 (64.27%), Query Frame = 2
Query: 500 SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGE----------SLFKKAI-------------EDMPDVEQLFNSHND--------------IGTVISNLTKNCF--FIPDFNLTAVTNLQYLKITAKHY----LFARMLSIWQNSD 2155
+ WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R++GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+VSTIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI+ +ILDF+TM+EI+ +G+TR+P++EGERSNI +L VKDLAF+DPDD P+ T+ FYN + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K++ R QDFS F ++ ++SPQL +A R LA+ V+ F ++ +L LL + N++ E + + + E ++++ K +Y +LILQGK E E + FEA F +G SL + + E+ +H+D +G+ + L + +IPD+++ A+++LQ++KI+ + Y + +RM Q+SD
Sbjct: 231 TTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTELLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAVTPTLGSSNNQLNSSLLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSD 829
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Match: CNNM4 (cyclin and CBS domain divalent metal cation transport mediator 4 [Source:HGNC Symbol;Acc:HGNC:105]) HSP 1 Score: 436.032 bits (1120), Expect = 5.312e-140 Identity = 264/604 (43.71%), Postives = 382/604 (63.25%), Query Frame = 2
Query: 440 ENFRLY-FCSKIQTNSTNSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQ-DFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLN-ANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG----------------ESLFKKAIEDMPD------VEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKG 2173
E+ +LY C++ Q + W+ + + SL F E LPLW+ I +I +L LSG+FSGLN+GLMALD EL+I++ G+ ++RYA+ I PIR++GN+LLC+LLLGNVLVN +L IL+D+L GSGLMAV STIGIVI GEI+PQA+C+RH L +GA TI +TKFFM++T LS+PI KLLD LG+E+ VY+R +L ++K + +VK+E +I GAL L TK V+DIMT L D FMI ++ILDF+TM+EI+ +G+TR+P++E E+SNI +L VKDLAF+DPDD P+ T+ FYN + V +T L ML +F++GK+H+A V+++ E +GDP+ ++GLVTLEDVIEEII++EI+DE+D++TDN ++R +N+ DFS F + ++SPQL +AA R LA+ V F I+ +L LL +++ E F + + + + ++ + K A+Y ILILQGK E E++ FE G F +G L + A PD L S N G+ + +I DF++ A+ +LQY+KIT + Y + S +NS P G
Sbjct: 143 ESMKLYALCTRAQPDGP------WLKWTDKDSLLFMVEEPGRFLPLWLHILLITVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERRYARKIEPIRRKGNYLLCSLLLGNVLVNTSLTILLDNLIGSGLMAVASSTIGIVIFGEILPQALCSRHGLAVGANTILLTKFFMLLTFPLSFPISKLLDFFLGQEIRTVYNREKLMEMLKVTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLQDCFMIRSDAILDFNTMSEIMESGYTRIPVFEDEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDMYTDNRSRKRVSEKNKRDFSAFKDADNELKVKISPQLLLAAHRFLATEVSQFSPSLISEKILLRLLKYPDVIQELKFDEHNKYYARHYLYTRNKPADYFILILQGKVEVEAGKENMKFETGAFSYYGTMALTSVPSDRSPAHPTPLSRSASLSYPDRTDVSTAATLAGSSNQFGSSVLGQ-----YISDFSVRALVDLQYIKITRQQYQNGLLASRMENSPQFPIDG 735
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Match: CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:HGNC Symbol;Acc:HGNC:103]) HSP 1 Score: 318.546 bits (815), Expect = 5.138e-98 Identity = 171/310 (55.16%), Postives = 232/310 (74.84%), Query Frame = 2
Query: 500 SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQ 1429
+ WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R++GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+VSTIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI+ +ILDF+TM+EI+ +G+TR+P++EGERSNI +L VKDLAF+DPDD P+ T+ FYN + V ++T L ML +F++
Sbjct: 231 TTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK 540
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Match: CNNM1 (cyclin and CBS domain divalent metal cation transport mediator 1 [Source:HGNC Symbol;Acc:HGNC:102]) HSP 1 Score: 290.041 bits (741), Expect = 1.164e-83 Identity = 191/538 (35.50%), Postives = 315/538 (58.55%), Query Frame = 2
Query: 656 DITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXA-----ILMDDLTGSG-----------LMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEG-ERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR---RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG-ESLFKKAIEDMPDVEQLFN--------------------------SHNDIGTVISNL--TKNCFFIPDFNLTAVTNLQYLKITAKHY 2116
D EL+++ +GS ++ A+ ++ +R RG LLCTLLLG N LA L G+G + +V T + + EI P ++C+RH L I + ++ +T+ M + YP+G+LLD L +E+ Y+R +L ++ +VK+E II GAL L TK V++++TPL D FM+ +++LDF T++EI+R+G+TR+P+YEG +R NI +L VKDLAF+DPDD P+ TV FYNR + V ++T L T+L +F++GK+H+A V+R+ E +GDP+ ++G+VTLED+IEEII++EI+DETD++TDN KKQR R + DFS+F + +T ++SPQL +A R +A+ V+ F +++ +L LL + N++ E F + + E+ ++++ + +Y +L+LQGK EV E L FE G F +G ++ A D DV ++ + +D G + L + N ++PD+++ ++++Q++KIT + Y
Sbjct: 250 DPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGWLYTSLPPGFGGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTEMRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTTACSDN-DVRKVGSLAGSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYMPDYSVHILSDVQFVKITRQQY 786
BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Match: cnnm-1 (Metal transporter cnnm-1 [Source:UniProtKB/Swiss-Prot;Acc:A3QM97]) HSP 1 Score: 338.191 bits (866), Expect = 6.004e-103 Identity = 245/708 (34.60%), Postives = 403/708 (56.92%), Query Frame = 2
Query: 131 VNSKSSEKIDNSIIPIIIGYKNKNKNSRWSSDLPSI----IEIPSQ--------------IETDFE--LYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFS---DYIATVKVKIDTVWKENFRLYFCSKIQTNSTNSQISQWIYQSSETS--LTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYE-GERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERL-ETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR-RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL--NANILVEHTFKSDVDCSENV-----IFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTV-ISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQ 2146
++S ++ DNS +P N N+ SS +P+I +E+P+ E +F+ +YG +L K+ I ++ +T+NC + V + HF ++ AT + + + + C K + + + + IY + S LT K+ LPL +QI+ I L LS LFSGL +GLM+L EL+++ ++G+ +++ A I P+RK+GN LLC+LLLGNV+VN+ ++ILM +LT +G+ A+I ST+GIVI GEI+PQ+IC + L +GA TI IT+ F+ +T +++P+ KLLD +LG E Q Y R +L L+K V +E I GA+ + K VKD+MT + DVFM+ ++L+ T+ EIV+ G+TR+P+Y+ G+++N+ +L VKDLA +DPDD V TVC ++ + V ++T L +L F++G+ H+A V+RL T+ DP VL+G+VTLED++EEI+QAEI DE D+ +DNV K + + +N+D + + +S QL++ AL+ L SN + F ++F+ NVL+ L+ +A + + D + NV ++ K + ++ ILIL+G+ + ++FEAGP+ FG + K ++ L S + +GT +S + F PD++ + YL+I+ Y+ A S+ Q
Sbjct: 39 LDSATTAAADNSTVPT---QSASNNNTSQSSKIPTIFGMRVELPADDPFGYDKHGVCSVTPEEEFKVVIYGNHLDKIHQIIWT-----FTNNC-SEPAYVIDALNHFKVHFNHKATFHLTLKLLPEMVHAYKMCVKPKVAPGSPPLGE-IYPLDDISTWLTTERPPKEYFLPLPLQIACIGFLLCLSALFSGLTLGLMSLTPQELELVIKSGAIKEQKCAAKILPVRKKGNLLLCSLLLGNVIVNSAISILMGELT-TGIYALIGSTMGIVIFGEILPQSICVKKGLEVGAHTISITQLFIFLTFPIAWPVSKLLDCLLGDEY-QAYDRKRLMELIKMSITDNGQVSNELKIAVGAMEIADKVVKDVMTKIEDVFMLPDTTVLNAKTVMEIVKMGYTRIPVYQYGDKNNVTDMLFVKDLALLDPDDNFTVKTVCGYHKHPVKFVMNDTPLPNLLEAFKKGEGHLAMVKRLINTDDKHDPSYVLVGVVTLEDIVEEILQAEINDEFDIVSDNVNKVKIKKEQNRDATKYFGDHEAPQTMISMQLQMVALQWLVSNERGFRQEFLDTNVLERLIRSSARRVDVSALMAMGDDAINVPRLAKVYTKDELSDKYILILEGRIQVTIGASGMMFEAGPWHHFGGEIMAKLVD---GAATLGRSMSIVGTSELSARRPDLMFKPDYSAVVKEDCTYLEISVSAYINAYKASLMQ 731
BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Match: cnnm-1 (Metal transporter cnnm-1 [Source:UniProtKB/Swiss-Prot;Acc:A3QM97]) HSP 1 Score: 338.191 bits (866), Expect = 6.004e-103 Identity = 245/708 (34.60%), Postives = 403/708 (56.92%), Query Frame = 2
Query: 131 VNSKSSEKIDNSIIPIIIGYKNKNKNSRWSSDLPSI----IEIPSQ--------------IETDFE--LYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFS---DYIATVKVKIDTVWKENFRLYFCSKIQTNSTNSQISQWIYQSSETS--LTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYE-GERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERL-ETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR-RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL--NANILVEHTFKSDVDCSENV-----IFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTV-ISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQ 2146
++S ++ DNS +P N N+ SS +P+I +E+P+ E +F+ +YG +L K+ I ++ +T+NC + V + HF ++ AT + + + + C K + + + + IY + S LT K+ LPL +QI+ I L LS LFSGL +GLM+L EL+++ ++G+ +++ A I P+RK+GN LLC+LLLGNV+VN+ ++ILM +LT +G+ A+I ST+GIVI GEI+PQ+IC + L +GA TI IT+ F+ +T +++P+ KLLD +LG E Q Y R +L L+K V +E I GA+ + K VKD+MT + DVFM+ ++L+ T+ EIV+ G+TR+P+Y+ G+++N+ +L VKDLA +DPDD V TVC ++ + V ++T L +L F++G+ H+A V+RL T+ DP VL+G+VTLED++EEI+QAEI DE D+ +DNV K + + +N+D + + +S QL++ AL+ L SN + F ++F+ NVL+ L+ +A + + D + NV ++ K + ++ ILIL+G+ + ++FEAGP+ FG + K ++ L S + +GT +S + F PD++ + YL+I+ Y+ A S+ Q
Sbjct: 39 LDSATTAAADNSTVPT---QSASNNNTSQSSKIPTIFGMRVELPADDPFGYDKHGVCSVTPEEEFKVVIYGNHLDKIHQIIWT-----FTNNC-SEPAYVIDALNHFKVHFNHKATFHLTLKLLPEMVHAYKMCVKPKVAPGSPPLGE-IYPLDDISTWLTTERPPKEYFLPLPLQIACIGFLLCLSALFSGLTLGLMSLTPQELELVIKSGAIKEQKCAAKILPVRKKGNLLLCSLLLGNVIVNSAISILMGELT-TGIYALIGSTMGIVIFGEILPQSICVKKGLEVGAHTISITQLFIFLTFPIAWPVSKLLDCLLGDEY-QAYDRKRLMELIKMSITDNGQVSNELKIAVGAMEIADKVVKDVMTKIEDVFMLPDTTVLNAKTVMEIVKMGYTRIPVYQYGDKNNVTDMLFVKDLALLDPDDNFTVKTVCGYHKHPVKFVMNDTPLPNLLEAFKKGEGHLAMVKRLINTDDKHDPSYVLVGVVTLEDIVEEILQAEINDEFDIVSDNVNKVKIKKEQNRDATKYFGDHEAPQTMISMQLQMVALQWLVSNERGFRQEFLDTNVLERLIRSSARRVDVSALMAMGDDAINVPRLAKVYTKDELSDKYILILEGRIQVTIGASGMMFEAGPWHHFGGEIMAKLVD---GAATLGRSMSIVGTSELSARRPDLMFKPDYSAVVKEDCTYLEISVSAYINAYKASLMQ 731
BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Match: cnnm-2 (Metal transporter cnnm-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9GYL2]) HSP 1 Score: 280.026 bits (715), Expect = 7.474e-82 Identity = 212/672 (31.55%), Postives = 342/672 (50.89%), Query Frame = 2
Query: 245 IPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIAT-VKVKID---TVWKENFRLYFCSKIQTNSTNSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIA-GALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSN---IKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERL---------------------------------ETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVF-TDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANI---LVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFA 2125
+ + E D ++G L V+ + F+ D+ VT + V+ + YI +K+ W + +R+ S+ WI T TF +P+W Q +I+ +LF++S L SGL +GLMAL EL I+ ++GS +K++A I PIR GN LLCT+++ NV+VN + +L DDL GL+A + ST+GIV+ GEI+PQ+IC ++ L +GA TI+ITKFFM + +++P+GK+LD G ++ V +EML + + L IA GA+ LT K+V+D+MT + DVFM+S + +L+ +TM +I +G+TR+P++EG N +K +L V DLA I D+ I V V F R + IV ++ L ++++F+ G H+A V + + E D L+GL+TLED+ EE++QAEI DETD + TD+ +K+RR ++ + K RLS + + L F + ++L+ NI L+ S + N +F+ G + +LIL+GKA + + L+FE GP+ FGE++ +K +E + + T FF+PD+NLT ++L+I+ L +
Sbjct: 54 VEANTEVDLVIFGHGLENVEMVTFT----------DSVCVTSEFNVSESTFYIHKDMKIVFKYAFVAWPQPWRICLKSECHGLIQIDDDRTWIQAVQSTHETF--------MPVWAQCAILCLLFSISALCSGLTLGLMALTPQELSILMKSGSQREKKHAAAIYPIRCHGNRLLCTVIIMNVIVNTGITLLFDDL-AEGLIAFVASTVGIVVFGEILPQSICVKYGLAVGANTIFITKFFMFLLFPITWPLGKILDKYAGVDIDVVNRSRMVEMLKMNMENDACDIDLSTLKIAIGAMELTKKSVRDVMTDIDDVFMLSEDQVLNAETMTKISDSGYTRIPVFEGNNRNKVAVKNLLYVSDLALIGKDNNITVKAVARFNKRRLRIVDESMPLTALMDEFKLGDYHLAMVAKATEVKKHHHGKFADGTVDSFILKSMKLVEATMMPQVENPEDHPVTLVGLITLEDITEELLQAEITDETDCYVTDDAQKKRRTNTSKKSAAELFCSEKKSERLSLHMLEMTEKWLLEKTPLFGN--MNPKAFENLIQRNIREVLIVPPKNSTSPGTLN-LFEAGVMSKRFLLILEGKATIRFNEKDLIFECGPWTCFGEAILEK-------MEMCISDRKEPST-------GFFFLPDYNLTVSGPCRFLQISTSSLLHS 689
BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Match: cnnm-3 (Metal transporter cnnm-3 [Source:UniProtKB/Swiss-Prot;Acc:A0A131MCZ8]) HSP 1 Score: 278.87 bits (712), Expect = 2.070e-81 Identity = 214/533 (40.15%), Postives = 307/533 (57.60%), Query Frame = 2
Query: 566 LPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQL-EML-VKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNV-KKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANI-LVEHTFKSD------VDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISN--LTKNCF-FIPDFNLTAVTNLQYLKITAKHYLFA 2125
+P W+ ++IL SGLFSGLN+GLM L EL++ +G+ +KR A I PIRK+GN LLCTLL+GNV+VN +++LMD L GSG ++ +T IV+ GEIIPQA+C + L IGA+TI IT+ + + L++PI K+LD+ L +EL + R +L EML + E+ +IG DE ++ GAL L K V MT D+FM+ L + +I+ G+TR+PIYE +R NI A+L VKDLA +DPDD V + + YN + V + LR ML +F++G+ HMA VERL + D DP L GL+TLED+IEEIIQ EI+DETD DNV +K+R+ RN D S K ++ Q+ ++ +++ K F ++I +L+ L+ N VE T S V V+F KG+ +N I+IL G+A+ + E + EAG + FG + E +E+ N TV N +T N FIPDF+ + + +ITA L A
Sbjct: 195 MPKWLSWICLLILLCFSGLFSGLNLGLMTLSPYELQLYIASGTEQEKRDAGRILPIRKKGNQLLCTLLIGNVVVNVGVSLLMDQLVGSGFAVLVAATSCIVVFGEIIPQALCVKLGLPIGARTIPITQVLLFLMYPLTWPISKVLDIFLKEELTRSLERNKLVEMLKLSEKSIIGGQ-SDEFKMVLGALELYDKTVAHAMTRYEDIFMLPHTLTLGAGMVTQILDMGYTRIPIYENDRKNIVALLFVKDLALLDPDDNHNVMKIASIYNHEVRRVLVDMPLRNMLEEFKRGEYHMALVERLVEQEDKDPIYELCGLITLEDIIEEIIQCEIIDETDAVCDNVHRKKRQRKRNHDMSQIVNTAHAKCA-INIQMLAVTIQVMSTCHKIFSSNYILPTILEKLIRKNCKKVETTQFSCLKEVGVVQPKPAVLFTKGEFSNKFIMILSGRAVVTIGKEEMRLEAGAWHSFGTEVLDAMAE---AIERSLNQSTSRSTVSLNTEITNNSIGFIPDFDTVILYECVFCEITAADLLLA 722
BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Match: cnnm-3 (Metal transporter cnnm-3 [Source:UniProtKB/Swiss-Prot;Acc:A0A131MCZ8]) HSP 1 Score: 279.256 bits (713), Expect = 3.073e-81 Identity = 214/533 (40.15%), Postives = 307/533 (57.60%), Query Frame = 2
Query: 566 LPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQL-EML-VKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNV-KKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANI-LVEHTFKSD------VDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISN--LTKNCF-FIPDFNLTAVTNLQYLKITAKHYLFA 2125
+P W+ ++IL SGLFSGLN+GLM L EL++ +G+ +KR A I PIRK+GN LLCTLL+GNV+VN +++LMD L GSG ++ +T IV+ GEIIPQA+C + L IGA+TI IT+ + + L++PI K+LD+ L +EL + R +L EML + E+ +IG DE ++ GAL L K V MT D+FM+ L + +I+ G+TR+PIYE +R NI A+L VKDLA +DPDD V + + YN + V + LR ML +F++G+ HMA VERL + D DP L GL+TLED+IEEIIQ EI+DETD DNV +K+R+ RN D S K ++ Q+ ++ +++ K F ++I +L+ L+ N VE T S V V+F KG+ +N I+IL G+A+ + E + EAG + FG + E +E+ N TV N +T N FIPDF+ + + +ITA L A
Sbjct: 195 MPKWLSWICLLILLCFSGLFSGLNLGLMTLSPYELQLYIASGTEQEKRDAGRILPIRKKGNQLLCTLLIGNVVVNVGVSLLMDQLVGSGFAVLVAATSCIVVFGEIIPQALCVKLGLPIGARTIPITQVLLFLMYPLTWPISKVLDIFLKEELTRSLERNKLVEMLKLSEKSIIGGQ-SDEFKMVLGALELYDKTVAHAMTRYEDIFMLPHTLTLGAGMVTQILDMGYTRIPIYENDRKNIVALLFVKDLALLDPDDNHNVMKIASIYNHEVRRVLVDMPLRNMLEEFKRGEYHMALVERLVEQEDKDPIYELCGLITLEDIIEEIIQCEIIDETDAVCDNVHRKKRQRKRNHDMSQIVNTAHAKCA-INIQMLAVTIQVMSTCHKIFSSNYILPTILEKLIRKNCKKVETTQFSCLKEVGVVQPKPAVLFTKGEFSNKFIMILSGRAVVTIGKEEMRLEAGAWHSFGTEVLDAMAE---AIERSLNQSTSRSTVSLNTEITNNSIGFIPDFDTVILYECVFCEITAADLLLA 722
BLAST of Metal transporter cnnm2 vs. Ensembl Fly
Match: uex (gene:FBgn0262124 transcript:FBtr0346683) HSP 1 Score: 431.795 bits (1109), Expect = 5.334e-138 Identity = 264/684 (38.60%), Postives = 419/684 (61.26%), Query Frame = 2
Query: 134 NSKSSEKIDNSIIPIIIGYKNKNKNSRWSSDLPSIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSD-YIATVKVKIDTVWKENFRLYFCSKIQTNSTN----SQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGK-AHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRR-LVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSEN---VIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG-ESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNS 2152
+S++ I NS I+G + +++ + +P+++ E F ++G+ L + I F+ +++ C + P+ S+ + A VK + E + C+K +TN + + +Q + L +T+E L+P+W+ I II+ S LFSGLN+GLM++D TELKI+ G+ +K+YA I P+R +GN+LLC++LLGNVLVN+T IL+D LT SGL AVI ST+ IV+ GEI PQA+C+RH L IGAKTI +TK M +T LSYP+ ++LD +LG+E+G VY+R +L+ LV+ + + K+E II+GAL L K V D+MT ++D FM+S++++LDF+T++EI+ +G++R+P+Y+G+R NI +L +KDLAF+D DD P+ T+C FY + V ++ L M N F++G H+AFV R+ E DGDP+ +GLVTLEDVIEE+IQAEI+DETDVF DN K RR + DFS F + R+SPQL +A ++L++ V F +D I+ +L+ LLN ++ H K+ ++ IF +GK ++ +LIL+G+ + E+L+FE+GPF FG ++L + D P S N + S + ++ F+PD+++ A++++ Y+ I YL A+ ++ + S
Sbjct: 45 SSRTRRTIANSFR--IVGIRLEDETVETKNGIPTVL---VDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINE---FFICAKTAEKTTNHSKAATTTPLEHQGNSDFLKIKTFE--PLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQGNYLLCSILLGNVLVNSTFTILLDGLT-SGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRRNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLNQDVF--HNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQALVPNVVIDSPTQMGSLQSLN----MDSKIRQS--FVPDYSVRAISDVIYITIKRVLYLTAKKATLLEKS 709
BLAST of Metal transporter cnnm2 vs. Ensembl Fly
Match: uex (gene:FBgn0262124 transcript:FBtr0302227) HSP 1 Score: 431.795 bits (1109), Expect = 5.334e-138 Identity = 264/684 (38.60%), Postives = 419/684 (61.26%), Query Frame = 2
Query: 134 NSKSSEKIDNSIIPIIIGYKNKNKNSRWSSDLPSIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSD-YIATVKVKIDTVWKENFRLYFCSKIQTNSTN----SQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGK-AHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRR-LVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSEN---VIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG-ESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNS 2152
+S++ I NS I+G + +++ + +P+++ E F ++G+ L + I F+ +++ C + P+ S+ + A VK + E + C+K +TN + + +Q + L +T+E L+P+W+ I II+ S LFSGLN+GLM++D TELKI+ G+ +K+YA I P+R +GN+LLC++LLGNVLVN+T IL+D LT SGL AVI ST+ IV+ GEI PQA+C+RH L IGAKTI +TK M +T LSYP+ ++LD +LG+E+G VY+R +L+ LV+ + + K+E II+GAL L K V D+MT ++D FM+S++++LDF+T++EI+ +G++R+P+Y+G+R NI +L +KDLAF+D DD P+ T+C FY + V ++ L M N F++G H+AFV R+ E DGDP+ +GLVTLEDVIEE+IQAEI+DETDVF DN K RR + DFS F + R+SPQL +A ++L++ V F +D I+ +L+ LLN ++ H K+ ++ IF +GK ++ +LIL+G+ + E+L+FE+GPF FG ++L + D P S N + S + ++ F+PD+++ A++++ Y+ I YL A+ ++ + S
Sbjct: 45 SSRTRRTIANSFR--IVGIRLEDETVETKNGIPTVL---VDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINE---FFICAKTAEKTTNHSKAATTTPLEHQGNSDFLKIKTFE--PLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQGNYLLCSILLGNVLVNSTFTILLDGLT-SGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRRNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLNQDVF--HNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQALVPNVVIDSPTQMGSLQSLN----MDSKIRQS--FVPDYSVRAISDVIYITIKRVLYLTAKKATLLEKS 709
BLAST of Metal transporter cnnm2 vs. Ensembl Fly
Match: uex (gene:FBgn0262124 transcript:FBtr0302226) HSP 1 Score: 431.795 bits (1109), Expect = 5.334e-138 Identity = 264/684 (38.60%), Postives = 419/684 (61.26%), Query Frame = 2
Query: 134 NSKSSEKIDNSIIPIIIGYKNKNKNSRWSSDLPSIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSD-YIATVKVKIDTVWKENFRLYFCSKIQTNSTN----SQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGK-AHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRR-LVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSEN---VIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG-ESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNS 2152
+S++ I NS I+G + +++ + +P+++ E F ++G+ L + I F+ +++ C + P+ S+ + A VK + E + C+K +TN + + +Q + L +T+E L+P+W+ I II+ S LFSGLN+GLM++D TELKI+ G+ +K+YA I P+R +GN+LLC++LLGNVLVN+T IL+D LT SGL AVI ST+ IV+ GEI PQA+C+RH L IGAKTI +TK M +T LSYP+ ++LD +LG+E+G VY+R +L+ LV+ + + K+E II+GAL L K V D+MT ++D FM+S++++LDF+T++EI+ +G++R+P+Y+G+R NI +L +KDLAF+D DD P+ T+C FY + V ++ L M N F++G H+AFV R+ E DGDP+ +GLVTLEDVIEE+IQAEI+DETDVF DN K RR + DFS F + R+SPQL +A ++L++ V F +D I+ +L+ LLN ++ H K+ ++ IF +GK ++ +LIL+G+ + E+L+FE+GPF FG ++L + D P S N + S + ++ F+PD+++ A++++ Y+ I YL A+ ++ + S
Sbjct: 45 SSRTRRTIANSFR--IVGIRLEDETVETKNGIPTVL---VDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINE---FFICAKTAEKTTNHSKAATTTPLEHQGNSDFLKIKTFE--PLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQGNYLLCSILLGNVLVNSTFTILLDGLT-SGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRRNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLNQDVF--HNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQALVPNVVIDSPTQMGSLQSLN----MDSKIRQS--FVPDYSVRAISDVIYITIKRVLYLTAKKATLLEKS 709
BLAST of Metal transporter cnnm2 vs. Ensembl Fly
Match: uex (gene:FBgn0262124 transcript:FBtr0334938) HSP 1 Score: 431.795 bits (1109), Expect = 5.334e-138 Identity = 264/684 (38.60%), Postives = 419/684 (61.26%), Query Frame = 2
Query: 134 NSKSSEKIDNSIIPIIIGYKNKNKNSRWSSDLPSIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSD-YIATVKVKIDTVWKENFRLYFCSKIQTNSTN----SQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGK-AHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRR-LVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSEN---VIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG-ESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNS 2152
+S++ I NS I+G + +++ + +P+++ E F ++G+ L + I F+ +++ C + P+ S+ + A VK + E + C+K +TN + + +Q + L +T+E L+P+W+ I II+ S LFSGLN+GLM++D TELKI+ G+ +K+YA I P+R +GN+LLC++LLGNVLVN+T IL+D LT SGL AVI ST+ IV+ GEI PQA+C+RH L IGAKTI +TK M +T LSYP+ ++LD +LG+E+G VY+R +L+ LV+ + + K+E II+GAL L K V D+MT ++D FM+S++++LDF+T++EI+ +G++R+P+Y+G+R NI +L +KDLAF+D DD P+ T+C FY + V ++ L M N F++G H+AFV R+ E DGDP+ +GLVTLEDVIEE+IQAEI+DETDVF DN K RR + DFS F + R+SPQL +A ++L++ V F +D I+ +L+ LLN ++ H K+ ++ IF +GK ++ +LIL+G+ + E+L+FE+GPF FG ++L + D P S N + S + ++ F+PD+++ A++++ Y+ I YL A+ ++ + S
Sbjct: 45 SSRTRRTIANSFR--IVGIRLEDETVETKNGIPTVL---VDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINE---FFICAKTAEKTTNHSKAATTTPLEHQGNSDFLKIKTFE--PLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQGNYLLCSILLGNVLVNSTFTILLDGLT-SGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRRNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLNQDVF--HNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQALVPNVVIDSPTQMGSLQSLN----MDSKIRQS--FVPDYSVRAISDVIYITIKRVLYLTAKKATLLEKS 709
BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Match: cnnm2a (cyclin and CBS domain divalent metal cation transport mediator 2a [Source:ZFIN;Acc:ZDB-GENE-050208-36]) HSP 1 Score: 461.07 bits (1185), Expect = 1.934e-149 Identity = 273/606 (45.05%), Postives = 382/606 (63.04%), Query Frame = 2
Query: 455 YFCSKIQTNSTNSQISQ--WIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVR--NQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG----------------------ESLFKKAIEDMPDVEQLFNSHND--------------IGTVISNLTKNCF---FIPDFNLTAVTNLQYLKITAKHYLFARMLS 2137
Y C+ I T S+ W+Y + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R +GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+VSTIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMIS ++ILDF TM+EI+ +G+TR+P+YEGER +I +L VKDLAF+DPDD P+ T+ FY+ + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K++ R QDFS F E ++SPQL +A LR LA+ V+ F ++ +L LL + N++ E + D SE+ +F + K +Y ILILQGK E E + FEAG F +G ESL P N H+D +G+ SN N F ++PD+++ AV++L Y+K+T + Y A M S
Sbjct: 157 YLCTAIGTPGAQDSWSEHTWVYHEGHDTKVIVVEEKKFLLPFWLQVIFIAMLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKHYAKAIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMILTFPASYPVSKLLDHVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMISGDAILDFATMSEIMESGYTRIPVYEGERCHIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKKIAHREKKQDFSAFKPTENELRVKISPQLLLATLRFLATEVESFSATQMSEKILLRLLKHPNVIQELKYDDKDKKMSEHYLFHRNKPVDYFILILQGKVEVEAGKEGMKFEAGAFSYYGVLSLTSSPVPLSLSRTFVVSRAESLAGSPENKSPPRPFGLN-HSDSLNRSDRMEAVTPTLGS--SNNQLNSFLQVYVPDYSVRAVSDLLYIKVTRQQYQNALMAS 759
BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Match: cnnm2b (cyclin and CBS domain divalent metal cation transport mediator 2b [Source:ZFIN;Acc:ZDB-GENE-090311-26]) HSP 1 Score: 457.218 bits (1175), Expect = 6.740e-148 Identity = 258/565 (45.66%), Postives = 376/565 (66.55%), Query Frame = 2
Query: 506 WIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTFK-SDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHND--------------IGTVISNLTKNCF---FIPDFNLTAVTNLQYLKITAKHYLFARMLS 2137
WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YA+ I P+R +GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV++STIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI+ ++ LDF++M+EI+ +G+TR+P++EG+RSNI +L VKDLAF+DPDD P+ T+ FY+ + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K++ R QDFS F + ++SPQL +A LR LA+ V+ F ++ +L LL + N++ E + + E+ +F + K +Y IL+LQGK E E L FEAG F +G + E+ +H+D +G+ SN N F ++PD+++ AV+++QY+K+T + Y A M S
Sbjct: 188 WIYHDGEDTKVIVVEEKKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEKEKNYARKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGDATLDFNSMSEIMESGYTRIPVFEGDRSNIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKKITHRERKQDFSAFKHMDNEMKVKISPQLLLATLRFLATEVEPFSPSQMSEKILLRLLKHPNVIQEVKYNDKNKKAIEHYLFHRNKPVDYFILVLQGKVEVEAGKEGLRFEAGAFSSYGMMALTASPENKSPPRSFGLNHSDSLNRSERIEVITPSLGS--SNNQLNAFLQIYVPDYSVRAVSDVQYIKVTRQQYQNAVMAS 750
BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Match: cnnm4b (cyclin and CBS domain divalent metal cation transport mediator 4b [Source:ZFIN;Acc:ZDB-GENE-070705-181]) HSP 1 Score: 455.292 bits (1170), Expect = 1.366e-147 Identity = 264/592 (44.59%), Postives = 391/592 (66.05%), Query Frame = 2
Query: 551 EKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQ---DFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG-ESLFKKAIE-------------------DMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGTIDQINY------APIHANESLGSLA 2233
EKKS+LP+W Q+ +I L LSG+FSGLN+GLMALD EL+I++ G+ +K+YA+ I PIR++GN+LLC+LLLGNVLVN TL IL+DDL GSGL AV+ STIGIVI GEI+PQA+C+RH L +GA TI +TKFFM +T LSYPI KLLD +LG+E+G VY+R +L ++K + +VK+E +I GAL L TK V+D+MTPL++ FMI+ +++LDF+TM+EI+ +G+TR+P+YE ER+NI +L VKDLAF+DPDD + T+ FYN + V +T L +ML +F++GK+H+A V+++ E +GDP+ ++GLVTLEDVIEEII+ EI+DE+D++TDN + ++++ N+ DFS F K ++SPQL +AA R LA+ V F I+ +L +L + +++ E F ++D S + ++ +GK +Y ILILQG+ E E++ FE GPF +G +L +E D P+ + + S+ + + S L + + PDFN+ A+ +LQ++KIT Y M S +S +P G Q++ AP +E++ +LA
Sbjct: 163 EKKSMLPIWFQVILICCLLVLSGMFSGLNLGLMALDPMELRIVQSCGTDKEKKYARKIEPIRRKGNYLLCSLLLGNVLVNTTLTILLDDLIGSGLGAVVASTIGIVIFGEIVPQALCSRHGLAVGANTIHVTKFFMFLTFPLSYPISKLLDCVLGQEIGTVYNREKLVGMLKVTEPYNDLVKEEMNMIQGALELRTKTVEDVMTPLNNCFMINSDAVLDFNTMSEIMESGYTRIPVYEDERTNIVDILFVKDLAFVDPDDCTTLKTITKFYNHPVHFVFHDTKLDSMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKCEILDESDLYTDN-RNRKKVAHNKNKRDFSAFKHESESKV-KISPQLLLAAHRFLATEVSLFSPSQISEKILLRILKHPDVIQEIKFNENDKKSSHHYLYLRGKPVDYFILILQGRVEVEAGNENMKFETGPFSFYGVMALSAPTLEFRSPSHISGLNRSASLSYTDRPESQSVSGSNTQLSS--SALPQ---YTPDFNVRALADLQFVKITRSQYQNGLMASRLDSSPQSPDSGHGRQVDMDNSTSSAPHRTSENMLTLA 747
BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Match: cnnm4b (cyclin and CBS domain divalent metal cation transport mediator 4b [Source:ZFIN;Acc:ZDB-GENE-070705-181]) HSP 1 Score: 412.149 bits (1058), Expect = 3.601e-133 Identity = 226/445 (50.79%), Postives = 327/445 (73.48%), Query Frame = 2
Query: 551 EKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQ---DFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQ 1870
EKKS+LP+W Q+ +I L LSG+FSGLN+GLMALD EL+I++ G+ +K+YA+ I PIR++GN+LLC+LLLGNVLVN TL IL+DDL GSGL AV+ STIGIVI GEI+PQA+C+RH L +GA TI +TKFFM +T LSYPI KLLD +LG+E+G VY+R +L ++K + +VK+E +I GAL L TK V+D+MTPL++ FMI+ +++LDF+TM+EI+ +G+TR+P+YE ER+NI +L VKDLAF+DPDD + T+ FYN + V +T L +ML +F++GK+H+A V+++ E +GDP+ ++GLVTLEDVIEEII+ EI+DE+D++TDN + ++++ N+ DFS F E+ ++SPQL +AA R LA+ V F I+ +L +L + +++ E F ++D S + ++ +GK +Y ILILQ
Sbjct: 160 EKKSMLPIWFQVILICCLLVLSGMFSGLNLGLMALDPMELRIVQSCGTDKEKKYARKIEPIRRKGNYLLCSLLLGNVLVNTTLTILLDDLIGSGLGAVVASTIGIVIFGEIVPQALCSRHGLAVGANTIHVTKFFMFLTFPLSYPISKLLDCVLGQEIGTVYNREKLVGMLKVTEPYNDLVKEEMNMIQGALELRTKTVEDVMTPLNNCFMINSDAVLDFNTMSEIMESGYTRIPVYEDERTNIVDILFVKDLAFVDPDDCTTLKTITKFYNHPVHFVFHDTKLDSMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKCEILDESDLYTDN-RNRKKVAHNKNKRDFSAFK-HESESKVKISPQLLLAAHRFLATEVSLFSPSQISEKILLRILKHPDVIQEIKFNENDKKSSHHYLYLRGKPVDYFILILQ 602
BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Match: cnnm2b (cyclin and CBS domain divalent metal cation transport mediator 2b [Source:ZFIN;Acc:ZDB-GENE-090311-26]) HSP 1 Score: 372.474 bits (955), Expect = 2.853e-118 Identity = 193/357 (54.06%), Postives = 273/357 (76.47%), Query Frame = 2
Query: 506 WIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFT 1576
WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YA+ I P+R +GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV++STIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI+ ++ LDF++M+EI+ +G+TR+P++EG+RSNI +L VKDLAF+DPDD P+ T+ FY+ + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD+++
Sbjct: 188 WIYHDGEDTKVIVVEEKKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEKEKNYARKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGDATLDFNSMSEIMESGYTRIPVFEGDRSNIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYS 544
BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Match: cnnm4 (cyclin and CBS domain divalent metal cation transport mediator 4 [Source:NCBI gene;Acc:100145459]) HSP 1 Score: 465.692 bits (1197), Expect = 4.125e-151 Identity = 265/597 (44.39%), Postives = 390/597 (65.33%), Query Frame = 2
Query: 455 YFCSKIQTNSTNSQI-----SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRL--VRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG-ESLFKKAIEDMPDVEQLFNSHND--------------IGTVISNLTKNCF--FIPDFNLTAVTNLQYLKITAKHY----LFARMLSIWQNSD 2155
Y C+ I T + + WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R++GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+VSTIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FM++ +++LDF+TM+EI+ +G+TR+P+YEGERSNI +L VKDLAF+DPDD P+ T+ FYN + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K++ + R QDFS F + ++SPQL +A R LA+ V F ++ +L LL + N++ E F + + +E ++++ K +Y +L+LQGK E E + FEAG F +G +L E+ +H+D +G + L + +IPD+++ A+T++Q++KIT + Y + +RM Q+SD
Sbjct: 156 YLCTSISTPPSGGHPQPWAETTWIYHDGEDTKVIVVEEKKFLLPFWLQVIFIAMLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEREKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMMAGDAVLDFNTMSEIMESGYTRIPVYEGERSNIVDLLFVKDLAFVDPDDCTPLKTITRFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVMHRERKQDFSAFKQTDNEMKVKISPQLLLAMHRFLATEVDAFSPSQMSEKILLRLLKHPNVIQELKFDERNKKSAEYYLYQRNKPVDYFVLVLQGKVEVEAGKEGMKFEAGAFSYYGVMALTASPAENKSPPRPCGLNHSDSLNRSDRIDAVTPTLGNSNNQLNASFLQVYIPDYSVRAITDMQFVKITRQQYQNALMASRMDKTPQSSD 752
BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Match: ihh (indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187]) HSP 1 Score: 447.588 bits (1150), Expect = 7.694e-145 Identity = 251/566 (44.35%), Postives = 374/566 (66.08%), Query Frame = 2
Query: 551 EKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVE--HTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSH----------------NDIGTVISN----LTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGT 2176
E+K LLP+W+Q II +L TLSG+FSGLN+GLMALD EL+++++ G+ +KRYA I P+R++GN+LLC+LLLGNVLVN TL L+D+L GSGL AV+ ST GIV+LGEI+PQA+C+RH L +GA T+W+T+ FM++T ++YP+ +LLD LG+E+G VY+R +L ++K + +V++E II GAL L TK V+D+MT + D FM+ +++LDF+TM+ I+ +G+TR+P+YE ERSNI +L VKDLAF+DPDD P++T+ FY+ + V +T L +L +F++GK+H+A V+++ +E +GDP+ ++GLVTLEDVIEEII++EI+DE+D++TDN K+R R +DFSVF + ++SPQL +AA R L++ V F ++ L LL +V+ H + D SEN ++++ K A+Y ILILQGK E E++ FE+G F +G AI E SH + I + IS L+ ++ DF++ A+ +LQ++KIT + Y A M S +S +P GT
Sbjct: 149 EEKPLLPIWLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYLLCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANTLWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKLLEMLKVTEPYSGIVREEMNIIQGALELRTKTVEDVMTKVEDCFMLPSDAVLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPDDCTPLSTITRFYSHPLHFVFSDTKLDAVLEEFKKGKSHLAIVQKVNSEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESDLYTDNRSKKRVKRRQDRKDFSVFKDADNELRVKISPQLLLAAHRFLSTEVPLFAPALVSEKTLLRLLKYPDVVQELHFNEDDKKASENFLYQRSKIADYFILILQGKVEVEAGKENMKFESGAFSYYG----VMAINTPSAAELRSPSHMSSLNRSISLSCHERSDSISSTISGSNTQLSAQAQYMADFSVRALGDLQFVKITREQYQGALMSSRLDSSPQSPEGGT 710
BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Match: ihh (indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187]) HSP 1 Score: 446.817 bits (1148), Expect = 4.352e-144 Identity = 251/566 (44.35%), Postives = 374/566 (66.08%), Query Frame = 2
Query: 551 EKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVE--HTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSH----------------NDIGTVISN----LTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGT 2176
E+K LLP+W+Q II +L TLSG+FSGLN+GLMALD EL+++++ G+ +KRYA I P+R++GN+LLC+LLLGNVLVN TL L+D+L GSGL AV+ ST GIV+LGEI+PQA+C+RH L +GA T+W+T+ FM++T ++YP+ +LLD LG+E+G VY+R +L ++K + +V++E II GAL L TK V+D+MT + D FM+ +++LDF+TM+ I+ +G+TR+P+YE ERSNI +L VKDLAF+DPDD P++T+ FY+ + V +T L +L +F++GK+H+A V+++ +E +GDP+ ++GLVTLEDVIEEII++EI+DE+D++TDN K+R R +DFSVF + ++SPQL +AA R L++ V F ++ L LL +V+ H + D SEN ++++ K A+Y ILILQGK E E++ FE+G F +G AI E SH + I + IS L+ ++ DF++ A+ +LQ++KIT + Y A M S +S +P GT
Sbjct: 180 EEKPLLPIWLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYLLCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANTLWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKLLEMLKVTEPYSGIVREEMNIIQGALELRTKTVEDVMTKVEDCFMLPSDAVLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPDDCTPLSTITRFYSHPLHFVFSDTKLDAVLEEFKKGKSHLAIVQKVNSEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESDLYTDNRSKKRVKRRQDRKDFSVFKDADNELRVKISPQLLLAAHRFLSTEVPLFAPALVSEKTLLRLLKYPDVVQELHFNEDDKKASENFLYQRSKIADYFILILQGKVEVEAGKENMKFESGAFSYYG----VMAINTPSAAELRSPSHMSSLNRSISLSCHERSDSISSTISGSNTQLSAQAQYMADFSVRALGDLQFVKITREQYQGALMSSRLDSSPQSPEGGT 741
BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Match: ihh (indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187]) HSP 1 Score: 442.965 bits (1138), Expect = 1.600e-142 Identity = 251/581 (43.20%), Postives = 377/581 (64.89%), Query Frame = 2
Query: 551 EKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVE--HTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG---------------------ESLFKKAIE-----DMPDVEQ-----LFNSHNDIGTVISN----LTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGT 2176
E+K LLP+W+Q II +L TLSG+FSGLN+GLMALD EL+++++ G+ +KRYA I P+R++GN+LLC+LLLGNVLVN TL L+D+L GSGL AV+ ST GIV+LGEI+PQA+C+RH L +GA T+W+T+ FM++T ++YP+ +LLD LG+E+G VY+R +L ++K + +V++E II GAL L TK V+D+MT + D FM+ +++LDF+TM+ I+ +G+TR+P+YE ERSNI +L VKDLAF+DPDD P++T+ FY+ + V +T L +L +F++GK+H+A V+++ +E +GDP+ ++GLVTLEDVIEEII++EI+DE+D++TDN K+R R +DFSVF + ++SPQL +AA R L++ V F ++ L LL +V+ H + D SEN ++++ K A+Y ILILQGK E E++ FE+G F +G SLF + E M + + + I + IS L+ ++ DF++ A+ +LQ++KIT + Y A M S +S +P GT
Sbjct: 172 EEKPLLPIWLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYLLCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANTLWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKLLEMLKVTEPYSGIVREEMNIIQGALELRTKTVEDVMTKVEDCFMLPSDAVLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPDDCTPLSTITRFYSHPLHFVFSDTKLDAVLEEFKKGKSHLAIVQKVNSEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESDLYTDNRSKKRVKRRQDRKDFSVFKDADNELRVKISPQLLLAAHRFLSTEVPLFAPALVSEKTLLRLLKYPDVVQELHFNEDDKKASENFLYQRSKIADYFILILQGKVEVEAGKENMKFESGAFSYYGVMAINTPSAAAPAHPCTVLKRGSLFSRLAELRSPSHMSSLNRSISLSCHERSDSISSTISGSNTQLSAQAQYMADFSVRALGDLQFVKITREQYQGALMSSRLDSSPQSPEGGT 752
BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Match: ihh (indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187]) HSP 1 Score: 430.639 bits (1106), Expect = 1.049e-137 Identity = 252/598 (42.14%), Postives = 374/598 (62.54%), Query Frame = 2
Query: 551 EKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLA--------------------------------SNVKYFCEDFITINVLQSLLNANILVE--HTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSH----------------NDIGTVISN----LTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGT 2176
E+K LLP+W+Q II +L TLSG+FSGLN+GLMALD EL+++++ G+ +KRYA I P+R++GN+LLC+LLLGNVLVN TL L+D+L GSGL AV+ ST GIV+LGEI+PQA+C+RH L +GA T+W+T+ FM++T ++YP+ +LLD LG+E+G VY+R +L ++K + +V++E II GAL L TK V+D+MT + D FM+ +++LDF+TM+ I+ +G+TR+P+YE ERSNI +L VKDLAF+DPDD P++T+ FY+ + V +T L +L +F++GK+H+A V+++ +E +GDP+ ++GLVTLEDVIEEII++EI+DE+D++TDN K+R R +DFSVF + ++SPQL +AA R L+ S V F ++ L LL +V+ H + D SEN ++++ K A+Y ILILQGK E E++ FE+G F +G AI E SH + I + IS L+ ++ DF++ A+ +LQ++KIT + Y A M S +S +P GT
Sbjct: 172 EEKPLLPIWLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYLLCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANTLWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKLLEMLKVTEPYSGIVREEMNIIQGALELRTKTVEDVMTKVEDCFMLPSDAVLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPDDCTPLSTITRFYSHPLHFVFSDTKLDAVLEEFKKGKSHLAIVQKVNSEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESDLYTDNRSKKRVKRRQDRKDFSVFKDADNELRVKISPQLLLAAHRFLSTGEICFPPDSVPPLHNSPLPHYVMGYVPYVLFSEVPLFAPALVSEKTLLRLLKYPDVVQELHFNEDDKKASENFLYQRSKIADYFILILQGKVEVEAGKENMKFESGAFSYYG----VMAINTPSAAELRSPSHMSSLNRSISLSCHERSDSISSTISGSNTQLSAQAQYMADFSVRALGDLQFVKITREQYQGALMSSRLDSSPQSPEGGT 765
BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Match: Cnnm2 (cyclin M2 [Source:MGI Symbol;Acc:MGI:2151054]) HSP 1 Score: 455.677 bits (1171), Expect = 8.114e-147 Identity = 260/577 (45.06%), Postives = 384/577 (66.55%), Query Frame = 2
Query: 500 SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG-ESLFKKAIEDMPDVEQLFNSHND--------------IGTVISNLTKNCF--FIPDFNLTAVTNLQYLKITAKHY----LFARMLSIWQNSD 2155
+ WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R++GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+VSTIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI+ +ILDF+TM+EI+ +G+TR+P++EGERSNI +L VKDLAF+DPDD P+ T+ FYN + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K++ R QDFS F ++ ++SPQL +A R LA+ V+ F ++ +L LL + N++ E + + + E ++++ K +Y +LILQGK E E + FEA F +G +L E+ +H+D +G+ + L+ + +IPD+++ A+++LQ++KI+ + Y + +RM Q+SD
Sbjct: 231 TTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPGENKSPPRPCGLNHSDSLSRSDRIDAMTPTLGSSNNQLSSSFLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSD 807
BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Match: Cnnm2 (cyclin M2 [Source:MGI Symbol;Acc:MGI:2151054]) HSP 1 Score: 446.432 bits (1147), Expect = 5.609e-143 Identity = 261/599 (43.57%), Postives = 386/599 (64.44%), Query Frame = 2
Query: 500 SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGE----------SLFKKAI-------------EDMPDVEQLFNSHND--------------IGTVISNLTKNCF--FIPDFNLTAVTNLQYLKITAKHY----LFARMLSIWQNSD 2155
+ WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R++GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+VSTIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI+ +ILDF+TM+EI+ +G+TR+P++EGERSNI +L VKDLAF+DPDD P+ T+ FYN + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K++ R QDFS F ++ ++SPQL +A R LA+ V+ F ++ +L LL + N++ E + + + E ++++ K +Y +LILQGK E E + FEA F +G SL + + E+ +H+D +G+ + L+ + +IPD+++ A+++LQ++KI+ + Y + +RM Q+SD
Sbjct: 231 TTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTEVLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAMTPTLGSSNNQLSSSFLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSD 829
BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Match: Cnnm4 (cyclin M4 [Source:MGI Symbol;Acc:MGI:2151060]) HSP 1 Score: 433.335 bits (1113), Expect = 3.136e-139 Identity = 260/601 (43.26%), Postives = 382/601 (63.56%), Query Frame = 2
Query: 440 ENFRLY-FCSKIQTNSTNSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQ-DFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLN-ANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIED----------------MPDVEQLFNSHNDIGTVISNLTKNCF---FIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKG 2173
EN +LY C++ + + W + + SL F E LPLW+ I ++++L LSG+FSGLN+GLMALD EL+I++ G+ +++YA+ I PIR++GN+LLC+LLLGNVLVN +L IL+D+L GSG+MAV STIGIVI GEI+PQA+C+RH L +GA TI +TK FM++T LS+PI KLLD +LG+E+ VY+R +L ++K + +VK+E +I GAL L TK V+DIMT L D FMI ++ILDF+TM+EI+ +G+TR+P++E E+SNI +L VKDLAF+DPDD P+ T+ FYN + V +T L ML +F++GK+H+A V+++ E +GDP+ ++GLVTLEDVIEEII++EI+DE+D++TDN ++R V+N+ DFS F + ++SPQL +AA R LA+ V F ++ +L LL +++ E F + + C + ++ + K A+ +LILQGK E E++ FE G F +G A D PD S + G SN +C ++ DF++ A+T+LQY+KIT + Y M S NS + G
Sbjct: 140 ENMKLYALCTRPRADGP------WTRWTDKDSLLFMVEEHGRFLPLWLHILLVMVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERKYARKIEPIRRKGNYLLCSLLLGNVLVNTSLTILLDNLIGSGIMAVASSTIGIVIFGEILPQALCSRHGLAVGANTIVLTKVFMLLTFPLSFPISKLLDFVLGQEIRTVYNREKLMEMLKVTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLHDCFMIRSDAILDFNTMSEIMESGYTRIPVFEDEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDMYTDNRTRKRVSVKNKRDFSAFKDTDNELKVKISPQLLLAAHRFLATEVPQFSPSLMSEKILLRLLKYPDVIQELRFNEHNRYCVRHYLYTRNKPADCFVLILQGKVEVEAGKENMKFETGAFSYYGTMALSVAPPDRSPALPTPLSRSASLSYPDRNTDLTSTSLAG---SNQFGSCILGQYVSDFSVRALTDLQYIKITRQQYQNGLMASRMDNSPQPTFDG 731
BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Match: Cnnm1 (cyclin M1 [Source:MGI Symbol;Acc:MGI:1891366]) HSP 1 Score: 287.73 bits (735), Expect = 4.815e-83 Identity = 190/538 (35.32%), Postives = 316/538 (58.74%), Query Frame = 2
Query: 656 DITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILM------------DDLTGSGL----MAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEG-ERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR---RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG-ESLFKKAIEDMPDVEQLFN--------------------------SHNDIGTVISNL--TKNCFFIPDFNLTAVTNLQYLKITAKHY 2116
D EL+++ +GS ++ A+ ++ +R RG LLCTLLLG N LA + +D +G+ + +V T + + EI P ++C+RH L I + ++ +T+ M + YP+G+LLD L +E+ Y+R +L ++ +VK+E II GAL L TK V++++TPL D FM+ +++LDF T++EI+R+G+TR+P+YEG +R NI +L VKDLAF+DPDD P+ TV FYNR + V ++T L T+L +F++GK+H+A V+R+ E +GDP+ ++G+VTLED+IEEII++EI+DETD++TDN KKQR R R DFS+F + ++ ++SPQL +A R +A+ V+ F +++ +L LL + N++ E F + + E+ ++++ + +Y +L+LQGK EV E L FE G F +G ++ A D DV ++ + +D G + L + N + PD+++ ++++Q++KIT + Y
Sbjct: 250 DPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGWLYASLPPGVGDPGEDSGEAGVHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTSACSDN-DVRKVGSLAGSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYTPDYSVHILSDVQFVKITRQQY 786
BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Match: Cnnm1 (cyclin M1 [Source:MGI Symbol;Acc:MGI:1891366]) HSP 1 Score: 282.722 bits (722), Expect = 3.905e-81 Identity = 184/489 (37.63%), Postives = 296/489 (60.53%), Query Frame = 2
Query: 656 DITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILM------------DDLTGSGL----MAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEG-ERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR---RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIP 2056
D EL+++ +GS ++ A+ ++ +R RG LLCTLLLG N LA + +D +G+ + +V T + + EI P ++C+RH L I + ++ +T+ M + YP+G+LLD L +E+ Y+R +L ++ +VK+E II GAL L TK V++++TPL D FM+ +++LDF T++EI+R+G+TR+P+YEG +R NI +L VKDLAF+DPDD P+ TV FYNR + V ++T L T+L +F++GK+H+A V+R+ E +GDP+ ++G+VTLED+IEEII++EI+DETD++TDN KKQR R R DFS+F + ++ ++SPQL +A R +A+ V+ F +++ +L LL + N++ E F + + E+ ++++ + +Y +L+LQGK EV E L FE G F +G +P + S ND+ V S L + F+P
Sbjct: 250 DPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGWLYASLPPGVGDPGEDSGEAGVHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYG----------VPAIMTSACSDNDVRKVGS-LAGSSVFLP 727
BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Match: sp|A0JPA0|CNNM4_XENTR (Metal transporter CNNM4 OS=Xenopus tropicalis OX=8364 GN=cnnm4 PE=2 SV=1) HSP 1 Score: 446.817 bits (1148), Expect = 1.801e-143 Identity = 251/566 (44.35%), Postives = 374/566 (66.08%), Query Frame = 2
Query: 551 EKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVE--HTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSH----------------NDIGTVISN----LTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGT 2176
E+K LLP+W+Q II +L TLSG+FSGLN+GLMALD EL+++++ G+ +KRYA I P+R++GN+LLC+LLLGNVLVN TL L+D+L GSGL AV+ ST GIV+LGEI+PQA+C+RH L +GA T+W+T+ FM++T ++YP+ +LLD LG+E+G VY+R +L ++K + +V++E II GAL L TK V+D+MT + D FM+ +++LDF+TM+ I+ +G+TR+P+YE ERSNI +L VKDLAF+DPDD P++T+ FY+ + V +T L +L +F++GK+H+A V+++ +E +GDP+ ++GLVTLEDVIEEII++EI+DE+D++TDN K+R R +DFSVF + ++SPQL +AA R L++ V F ++ L LL +V+ H + D SEN ++++ K A+Y ILILQGK E E++ FE+G F +G AI E SH + I + IS L+ ++ DF++ A+ +LQ++KIT + Y A M S +S +P GT
Sbjct: 172 EEKPLLPIWLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYLLCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANTLWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKLLEMLKVTEPYSGIVREEMNIIQGALELRTKTVEDVMTKVEDCFMLPSDAVLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPDDCTPLSTITRFYSHPLHFVFSDTKLDAVLEEFKKGKSHLAIVQKVNSEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESDLYTDNRSKKRVKRRQDRKDFSVFKDADNELRVKISPQLLLAAHRFLSTEVPLFAPALVSEKTLLRLLKYPDVVQELHFNEDDKKASENFLYQRSKIADYFILILQGKVEVEAGKENMKFESGAFSYYG----VMAINTPSAAELRSPSHMSSLNRSISLSCHERSDSISSTISGSNTQLSAQAQYMADFSVRALGDLQFVKITREQYQGALMSSRLDSSPQSPEGGT 733
BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Match: sp|Q5U2P1|CNNM2_RAT (Metal transporter CNNM2 OS=Rattus norvegicus OX=10116 GN=Cnnm2 PE=2 SV=1) HSP 1 Score: 446.817 bits (1148), Expect = 2.541e-142 Identity = 261/599 (43.57%), Postives = 386/599 (64.44%), Query Frame = 2
Query: 500 SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGE----------SLFKKAI-------------EDMPDVEQLFNSHND--------------IGTVISNLTKNCF--FIPDFNLTAVTNLQYLKITAKHY----LFARMLSIWQNSD 2155
+ WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R++GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+VSTIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI+ +ILDF+TM+EI+ +G+TR+P++EGERSNI +L VKDLAF+DPDD P+ T+ FYN + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K++ R QDFS F ++ ++SPQL +A R LA+ V+ F ++ +L LL + N++ E + + + E ++++ K +Y +LILQGK E E + FEA F +G SL + + E+ +H+D +G+ + L+ + +IPD+++ A+++LQ++KI+ + Y + +RM Q+SD
Sbjct: 231 TTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSETKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTEVLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAMTPTLGSSNNQLSSSFLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSD 829
BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Match: sp|Q9H8M5|CNNM2_HUMAN (Metal transporter CNNM2 OS=Homo sapiens OX=9606 GN=CNNM2 PE=1 SV=2) HSP 1 Score: 446.432 bits (1147), Expect = 3.567e-142 Identity = 261/599 (43.57%), Postives = 385/599 (64.27%), Query Frame = 2
Query: 500 SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGE----------SLFKKAI-------------EDMPDVEQLFNSHND--------------IGTVISNLTKNCF--FIPDFNLTAVTNLQYLKITAKHY----LFARMLSIWQNSD 2155
+ WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R++GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+VSTIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI+ +ILDF+TM+EI+ +G+TR+P++EGERSNI +L VKDLAF+DPDD P+ T+ FYN + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K++ R QDFS F ++ ++SPQL +A R LA+ V+ F ++ +L LL + N++ E + + + E ++++ K +Y +LILQGK E E + FEA F +G SL + + E+ +H+D +G+ + L + +IPD+++ A+++LQ++KI+ + Y + +RM Q+SD
Sbjct: 231 TTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTELLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAVTPTLGSSNNQLNSSLLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSD 829
BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Match: sp|Q3TWN3|CNNM2_MOUSE (Metal transporter CNNM2 OS=Mus musculus OX=10090 GN=Cnnm2 PE=1 SV=3) HSP 1 Score: 446.432 bits (1147), Expect = 3.924e-142 Identity = 261/599 (43.57%), Postives = 386/599 (64.44%), Query Frame = 2
Query: 500 SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGE----------SLFKKAI-------------EDMPDVEQLFNSHND--------------IGTVISNLTKNCF--FIPDFNLTAVTNLQYLKITAKHY----LFARMLSIWQNSD 2155
+ WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R++GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+VSTIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI+ +ILDF+TM+EI+ +G+TR+P++EGERSNI +L VKDLAF+DPDD P+ T+ FYN + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K++ R QDFS F ++ ++SPQL +A R LA+ V+ F ++ +L LL + N++ E + + + E ++++ K +Y +LILQGK E E + FEA F +G SL + + E+ +H+D +G+ + L+ + +IPD+++ A+++LQ++KI+ + Y + +RM Q+SD
Sbjct: 231 TTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTEVLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAMTPTLGSSNNQLSSSFLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSD 829
BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Match: sp|Q6P4Q7|CNNM4_HUMAN (Metal transporter CNNM4 OS=Homo sapiens OX=9606 GN=CNNM4 PE=1 SV=3) HSP 1 Score: 436.032 bits (1120), Expect = 2.551e-139 Identity = 264/604 (43.71%), Postives = 382/604 (63.25%), Query Frame = 2
Query: 440 ENFRLY-FCSKIQTNSTNSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQ-DFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLN-ANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG----------------ESLFKKAIEDMPD------VEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKG 2173
E+ +LY C++ Q + W+ + + SL F E LPLW+ I +I +L LSG+FSGLN+GLMALD EL+I++ G+ ++RYA+ I PIR++GN+LLC+LLLGNVLVN +L IL+D+L GSGLMAV STIGIVI GEI+PQA+C+RH L +GA TI +TKFFM++T LS+PI KLLD LG+E+ VY+R +L ++K + +VK+E +I GAL L TK V+DIMT L D FMI ++ILDF+TM+EI+ +G+TR+P++E E+SNI +L VKDLAF+DPDD P+ T+ FYN + V +T L ML +F++GK+H+A V+++ E +GDP+ ++GLVTLEDVIEEII++EI+DE+D++TDN ++R +N+ DFS F + ++SPQL +AA R LA+ V F I+ +L LL +++ E F + + + + ++ + K A+Y ILILQGK E E++ FE G F +G L + A PD L S N G+ + +I DF++ A+ +LQY+KIT + Y + S +NS P G
Sbjct: 143 ESMKLYALCTRAQPDGP------WLKWTDKDSLLFMVEEPGRFLPLWLHILLITVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERRYARKIEPIRRKGNYLLCSLLLGNVLVNTSLTILLDNLIGSGLMAVASSTIGIVIFGEILPQALCSRHGLAVGANTILLTKFFMLLTFPLSFPISKLLDFFLGQEIRTVYNREKLMEMLKVTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLQDCFMIRSDAILDFNTMSEIMESGYTRIPVFEDEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDMYTDNRSRKRVSEKNKRDFSAFKDADNELKVKISPQLLLAAHRFLATEVSQFSPSLISEKILLRLLKYPDVIQELKFDEHNKYYARHYLYTRNKPADYFILILQGKVEVEAGKENMKFETGAFSYYGTMALTSVPSDRSPAHPTPLSRSASLSYPDRTDVSTAATLAGSSNQFGSSVLGQ-----YISDFSVRALVDLQYIKITRQQYQNGLLASRMENSPQFPIDG 735
BLAST of Metal transporter cnnm2 vs. TrEMBL
Match: A0A0X3QHH6 (Metal transporter CNNM4 OS=Schistocephalus solidus OX=70667 GN=CNNM4 PE=4 SV=1) HSP 1 Score: 681.789 bits (1758), Expect = 0.000e+0 Identity = 370/708 (52.26%), Postives = 482/708 (68.08%), Query Frame = 2
Query: 239 IEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSKIQTN-STNSQISQWIY-QSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPR--LSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPY--KGTIDQINYAPIHANESLGSLALRNKKSITTTSMQLM----------RDFYQREWEKYI 2314
IE+P +YG L V +AF+ +C+ R T+A P+ + + Y + + Y C K+ ++ WI+ + + L+P+W+QI +II+LF LSGLFSGLN+GLM+LD TELKIIE AG ++KRYAK IRP+R++GN LLCT+LLGNVLVN +L ILMD+LTGSGL AVI ST+GI + GEIIPQAIC+RH L IGAKTIW+TK FMV+T L++PI LLD ILG E+G VYSR +L +L+KEQQ G V DE IIAGAL ++TK V DIM+P++D FM+ +ILDFDTMNEI +GFTR+PIYEG+R NIKA+LNVKDL FI+ DD++PV TVC FYNRSIL+VPD T L TMLN+FRQGKAHMAFVERL T+ GDPYR +IGLVTLEDVIEEIIQAEI+DETDVFTDN +Q R VR DF +FN + K PR LSPQLK+AALRHLASNV+ F ++++T+ VLQSLLN+N++ +H F S D +EN+I++ + ANYAILILQG+A+ E S E L+FEAGPF+LFGE++ K E P+V L D + L F+PD+ + A+TN+Q+L+ITA+HYL AR LS W + L P G D N P++ +LA+ + ++ T L +DF+Q W++++
Sbjct: 39 IEVPPDKPIAVTIYGDNLQNVTSVAFATTHKMKDSSCEMDRATLASPIFNKTVYSIRTLITFRQMAPSEPAFYLCLKVSPPLKVGNETLAWIHVLPTPVAGHLLLVTATQLMPIWLQIVLIIVLFFLSGLFSGLNLGLMSLDKTELKIIETAGDPDEKRYAKAIRPVREKGNLLLCTVLLGNVLVNTSLTILMDNLTGSGLFAVIASTLGITLFGEIIPQAICSRHGLAIGAKTIWLTKLFMVLTFPLAFPISFLLDKILGDEIGAVYSREKLGVLLKEQQDAGLVAPDEMNIIAGALNMSTKTVADIMSPIADAFMLPHTAILDFDTMNEIFSHGFTRIPIYEGDRRNIKAILNVKDLGFINADDRVPVATVCNFYNRSILVVPDTTSLETMLNEFRQGKAHMAFVERLVTDGQGDPYREMIGLVTLEDVIEEIIQAEIVDETDVFTDNTFRQARPVRKNDFRMFNTSNSNK-PRHHLSPQLKIAALRHLASNVETFSDEYVTLPVLQSLLNSNVVTDHVFNSR-DENENIIYRANQWANYAILILQGRALVETSAEHLVFEAGPFMLFGETVLKDVNEIYPEVSSL----KDPELQSAQLAAKARFLPDYTVRAITNIQFLRITAEHYLLARRLSAWI-TKLHPQGNNGVPDAQNLLPVNVTSEADALAVVREPTLPTQPPGLAPPFLRSEANTQDFFQAAWDRHV 739
BLAST of Metal transporter cnnm2 vs. TrEMBL
Match: A0A158QSG6 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS816 PE=4 SV=1) HSP 1 Score: 680.248 bits (1754), Expect = 0.000e+0 Identity = 357/644 (55.43%), Postives = 464/644 (72.05%), Query Frame = 2
Query: 233 SIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSK-----IQTNSTNSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPR--LSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIW 2143
+IE+P+ +YG VKY++F+ + +CDT R T A V + + Y V++ + Y C K IQ N++ S W++ + S F +++PLW+QI +II+LF LSGLFSGLN+GLMALD TELKIIE AG ++KRYAK IRPIR++GN LLCT+LLGNV VN TL ILMD+LTGSGL AVI ST+GI GEI+PQAIC+RH L IGAKTIW+T+FFMV+T +++PI +LD +LG++LGQVYS+ +L +L+ EQQ G V DE IIAGAL ++TK V DIM+PLSD FM+ +ILDFDTMNEI +GFTR+P+YEG+R NIKA+LNVKDL FI+ DDK+P+ TVCTFYNRSI++VP+ T L TML +FRQGK HMAFVERL T GDPYR +IGLVTLEDVIEEIIQAEI+DETD+FTDN ++Q R+VR DF VFN + K PR LSPQLK+AALRHLASNV+ F +++I ++VLQS+LN+N+++ H F S D + N+I+K + ANYA+LILQG+A+ E S E LLFEAGPF+LFGE++ K + P+V L D + L F+PD+ + AVTN++YL+ITA+HYL AR L++W
Sbjct: 42 GVIEVPADKTLHLYIYGGNFENVKYLSFATTKNETGVSCDTHRATTASEVRNTTSYSLETSVRLRKLTSFESAFYICFKLVKPIIQNNNSIS----WVFAAPSNSTVFALRTASTIMPLWLQIILIIVLFFLSGLFSGLNLGLMALDKTELKIIETAGDPDEKRYAKAIRPIREKGNLLLCTILLGNVTVNTTLTILMDNLTGSGLFAVIASTLGITTFGEILPQAICSRHGLAIGAKTIWLTRFFMVLTFPIAFPISFMLDKMLGEDLGQVYSKEKLGVLLMEQQNAGLVAPDEMNIIAGALNMSTKTVGDIMSPLSDAFMLPNTAILDFDTMNEIFSHGFTRIPVYEGDRKNIKAILNVKDLGFINADDKVPLATVCTFYNRSIVVVPETTSLETMLKEFRQGKTHMAFVERLVTGGQGDPYREMIGLVTLEDVIEEIIQAEIVDETDIFTDNTRRQPRVVRKTDFRVFNTSNSDK-PRHHLSPQLKIAALRHLASNVETFKDEYIALSVLQSMLNSNVVIHHVFNSR-DDNANIIYKASQWANYAVLILQGRALVETSNEKLLFEAGPFMLFGETVLKYVNDIYPEVSSL----KDPELQSAQLAARARFLPDYTVRAVTNVEYLRITAEHYLLARRLTVW 675
BLAST of Metal transporter cnnm2 vs. TrEMBL
Match: A0A5K3EZ15 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 679.093 bits (1751), Expect = 0.000e+0 Identity = 357/644 (55.43%), Postives = 464/644 (72.05%), Query Frame = 2
Query: 233 SIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSK-----IQTNSTNSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPR--LSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIW 2143
+IE+P+ +YG VKY++F+ + +CDT R T A V + + Y V++ + Y C K IQ N++ S W++ + S F +++PLW+QI +II+LF LSGLFSGLN+GLMALD TELKIIE AG ++KRYAK IRPIR++GN LLCT+LLGNV VN TL ILMD+LTGSGL AVI ST+GI GEI+PQAIC+RH L IGAKTIW+T+FFMV+T +++PI +LD +LG++LGQVYS+ +L +L+ EQQ G V DE IIAGAL ++TK V DIM+PLSD FM+ +ILDFDTMNEI +GFTR+P+YEG+R NIKA+LNVKDL FI+ DDK+P+ TVCTFYNRSI++VP+ T L TML +FRQGK HMAFVERL T GDPYR +IGLVTLEDVIEEIIQAEI+DETD+FTDN ++Q R+VR DF VFN + K PR LSPQLK+AALRHLASNV+ F +++I ++VLQS+LN+N+++ H F S D + N+I+K + ANYA+LILQG+A+ E S E LLFEAGPF+LFGE++ K + P+V L D + L F+PD+ + AVTN++YL+ITA+HYL AR L++W
Sbjct: 42 GVIEVPADKTLHLYIYGGNFENVKYLSFATTKNETGVSCDTHRATTASEVRNTTSYSLETSVRLRKLTSFESAFYICFKLVKPIIQNNNSIS----WVFAAPSNSTVFALRTASTIMPLWLQIILIIVLFFLSGLFSGLNLGLMALDKTELKIIETAGDPDEKRYAKAIRPIREKGNLLLCTILLGNVTVNTTLTILMDNLTGSGLFAVIASTLGITTFGEILPQAICSRHGLAIGAKTIWLTRFFMVLTFPIAFPISFMLDKMLGEDLGQVYSKEKLGVLLMEQQNAGLVAPDEMNIIAGALNMSTKTVGDIMSPLSDAFMLPNTAILDFDTMNEIFSHGFTRIPVYEGDRKNIKAILNVKDLGFINADDKVPLATVCTFYNRSIVVVPETTSLETMLKEFRQGKTHMAFVERLVTGGQGDPYREMIGLVTLEDVIEEIIQAEIVDETDIFTDNTRRQPRVVRKTDFRVFNTSNSDK-PRHHLSPQLKIAALRHLASNVETFKDEYIALSVLQSMLNSNVVIHHVFNSR-DDNANIIYKASQWANYAVLILQGRALVETSNEKLLFEAGPFMLFGETVLKYVNDIYPEVSSL----KDPELQSAQLAARARFLPDYTVRAVTNVEYLRITAEHYLLARRLTVW 675
BLAST of Metal transporter cnnm2 vs. TrEMBL
Match: A0A4S2LT54 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005039 PE=4 SV=1) HSP 1 Score: 677.552 bits (1747), Expect = 0.000e+0 Identity = 368/690 (53.33%), Postives = 483/690 (70.00%), Query Frame = 2
Query: 275 LYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSKI---QT----NSTNSQISQWIYQSSE---TSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGTIDQINYAPIHANESLGSLALRNKKSITTTSMQLMRDFYQREWEKYI 2314
L+GT L +V +IAF+ + CD R T + ++ S Y+AT +K+ + + + C +I QT STN+ W Y E L FRT KSL+P+W+QI +II+LF LSGLFSGLN+GLM+LD TELKIIE AGS N+K YAK IRP+R++GN LLCTLLLGNVLVN +L ILMDDLTGSGL AVI ST GI + GEI+PQA+C+RH L +GA+T+W+TK FM++T +++PI LLD ILG+E+GQVYSR +L +L++EQ L G+V DE II GAL LTTK V D+MTPLSD FM+S ++ LDF+TMN+I +G+TR+P++E +R NI+AVLNVKDLAFI+ DDK+PV+TVC FYNRSI+IV D T L ML +FRQG+AHMAFVERL TE +GDPYR +IGLVTLEDVIEEIIQAEI+DETD+ TDNV Q RLVR +DF +F++PE ++ RLSPQLK+AALRHLASNV+ F E + +VLQS LN+NI+ E + D N+++ + ANYAILILQG+A+ ++ E LLFEAGPFV+FGE++ K+ PD+ +D + L F+PD++L AVTNLQYL+ITA+HYL AR LSI AP+ +N++ A S GS ++ + S D +Q W+ ++
Sbjct: 66 LFGTDLDQVSHIAFASVKKPPDSPCDIERSTETFRLSPKSPYVATTVIKLRELGMNDDGFFLCVRIIPTQTIGLSLSTNASSESWFYAGVEGFDNHLIFRT--SKSLMPIWVQIILIIVLFFLSGLFSGLNLGLMSLDKTELKIIESAGSPNEKIYAKAIRPVREKGNLLLCTLLLGNVLVNTSLTILMDDLTGSGLFAVIGSTTGITLFGEIMPQAVCSRHGLAVGARTLWLTKLFMLITFPVAFPISFLLDKILGEEMGQVYSREKLGVLIREQALAGTVATDEMNIITGALALTTKTVADVMTPLSDAFMLSYSATLDFNTMNDIYAHGYTRIPVFEHDRRNIRAVLNVKDLAFINADDKVPVSTVCDFYNRSIIIVLDTTNLEAMLKEFRQGRAHMAFVERLVTEGEGDPYREMIGLVTLEDVIEEIIQAEIVDETDILTDNVHHQPRLVRRRDFRMFSMPEKQRHSRLSPQLKIAALRHLASNVESFQEHLVCYSVLQSFLNSNIVGECIYNPK-DEESNILYLPNQWANYAILILQGRALCKIGNEGLLFEAGPFVMFGETVLKRVNAIFPDL----CDKSDPTVHSARLASEARFVPDYSLKAVTNLQYLRITAEHYLLARRLSIVHQK-AAPHSNQHSPVNFSDHCALSSCGSHFVQGFGPLKIDS----HDMFQSAWDHHV 743
BLAST of Metal transporter cnnm2 vs. TrEMBL
Match: H2KNU9 (Metal transporter CNNM4 OS=Clonorchis sinensis OX=79923 GN=CLF_100799 PE=4 SV=1) HSP 1 Score: 676.011 bits (1743), Expect = 0.000e+0 Identity = 367/690 (53.19%), Postives = 481/690 (69.71%), Query Frame = 2
Query: 275 LYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSKI---QTN----STNSQISQWIYQSSE---TSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGTIDQINYAPIHANESLGSLALRNKKSITTTSMQLMRDFYQREWEKYI 2314
L+GT L ++ +IAF+ + CD R T + ++ S Y+AT +K+ + + + C +I QT STN+ W Y E L FRT KSL+P+W+QI +II+LF LSGLFSGLN+GLM+LD TELKIIE AGS N+K YAK IRP+R++GN LLCTLLLGNVLVN +L ILMDDLTGSGL AVI ST GI + GEI+PQA+C+RH L +GA+T+W+TK FM++T +++PI LLD ILG+E+GQVYSR +L +L++EQ L G+V DE II GAL LTTK V D+MTPLSD FM+S + LDF+TMN+I +G+TR+P++E +R NI+AVLNVKDLAFI+ DDK+PV+TVC FYNRSI+IV D T L ML +FRQG+AHMAFVERL TE +GDPYR +IGLVTLEDVIEEIIQAEI+DETD+ TDNV Q RLVR +DF +F++PE ++ RLSPQLK+AALRHLASNV+ F E + +VLQS LN+NI+ E + D N+++ + ANYAILILQG+A+ ++ E LLFEAGPFV+FGE++ K+ PD+ +D + L F+PD++L AVTNLQYL+ITA+HYL AR LSI AP+ +N++ A S GS + + S D +Q W+ ++
Sbjct: 56 LFGTDLDQISHIAFASVKKPPDSPCDIERSTETFRLSPKSPYVATTVIKLRELGMNDDGFFLCVRIIPAQTPGLSLSTNASSESWFYAGVEGFDNHLIFRT--SKSLMPIWVQIILIIVLFFLSGLFSGLNLGLMSLDKTELKIIESAGSPNEKIYAKAIRPVREKGNLLLCTLLLGNVLVNTSLTILMDDLTGSGLFAVIGSTTGITLFGEIMPQAVCSRHGLAVGARTLWLTKLFMLITFPVAFPISFLLDKILGEEMGQVYSREKLGVLIREQALAGTVATDEMNIITGALALTTKTVADVMTPLSDAFMLSYAATLDFNTMNDIYAHGYTRIPVFEHDRRNIRAVLNVKDLAFINADDKVPVSTVCDFYNRSIIIVLDTTNLEAMLKEFRQGRAHMAFVERLVTEGEGDPYREMIGLVTLEDVIEEIIQAEIVDETDILTDNVHHQPRLVRRRDFRMFSMPEKQRHSRLSPQLKIAALRHLASNVESFQEHLVCYSVLQSFLNSNIVGECIYNPK-DEESNILYLPNQWANYAILILQGRALCKIGNEGLLFEAGPFVMFGETVLKRVNAIFPDL----CDKSDPTVHSARLASEARFVPDYSLKAVTNLQYLRITAEHYLLARRLSIVHQK-AAPHSNQHSPVNFSDHCALSSCGSHFVHGFGPLKIDS----HDMFQSAWDHHV 733
BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Match: cnnm2a (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:NCBI gene;Acc:103036966]) HSP 1 Score: 456.447 bits (1173), Expect = 7.245e-148 Identity = 263/588 (44.73%), Postives = 381/588 (64.80%), Query Frame = 2
Query: 440 ENFRLY-FCSKIQTNSTNSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHND--------------IGTVISNLTKNCF---FIPDFNLTAVTNLQYLKITAKHYLFARMLS 2137
E +LY C Q + + S W+Y + E+K LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ ++ YAK I P+R +GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+ STIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI ++ILDF+TM+EI+ +G+TR+P++EGER NI +L VKDLAF+DPDD P+ T+ FY+ + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K+R R QDFS F + ++SPQL +A LR LA+ V+ F ++ +L LL + N++ E + + E+ +F + K +Y ILILQGK E E + F+AGPF +G + E+ +H+D +G+ SN N F ++PD+++ A ++L Y+K+T + Y A M S
Sbjct: 156 EKSKLYHLCIATQDDEMRPE-SIWVYHEGHDTKVLVVEERKFLLPFWLQVIFIAMLLCLSGMFSGLNLGLMALDPMELRIVQNCGTERERNYAKYIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVASTIGIVIFGEIMPQAICSRHGLAVGANTIFLTKFFMILTFPASYPVSKLLDHVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMIIGDAILDFNTMSEIMESGYTRIPVFEGERCNIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKRIAHRERKQDFSAFKPTDNNLGVKISPQLLLATLRFLATEVEPFGPAQMSEKILLRLLKHPNVIQELKYDDKNKKMLEHYLFHRNKPVDYFILILQGKVEVEAGKEGMKFKAGPFSYYGMMALTSSPENKSPPRPFGLNHSDSVNRNDRMEALTPTLGS--SNNQLNAFLQIYVPDYSVRAASDLLYIKVTRQQYQNALMAS 740
BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Match: cnnm2b (metal transporter CNNM2-like [Source:NCBI gene;Acc:103025617]) HSP 1 Score: 449.514 bits (1155), Expect = 1.557e-144 Identity = 261/585 (44.62%), Postives = 377/585 (64.44%), Query Frame = 2
Query: 455 YFCSKIQTNSTNSQI---SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTFK-SDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHND--------------IGTVISNLTKNCF---FIPDFNLTAVTNLQYLKITAKHYLFARMLS 2137
Y C T++ S WIY E + E+K LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YA+ I P+R +GN+LLC+LLLGNVLVN TL IL+DD+ G+GL+AV++STIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V D+MTPL D FMI+ ++ LDF TM+EI+ +G+TR+P++E ERSNI +L VKDLAF+DPDD P+ T+ FY+ + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K+R R QDFS F + ++SPQL +A LR LA++++ F I+ +L LL + N++ E F + E+ ++ + K +Y ILILQGK E + + FEAG F +G + E+ +H+D +G+ SN N F + PD+ + A+T+L Y+K+T + Y A M S
Sbjct: 208 YLCIATSTSAGTHDPWTESTWIYHEGEDTKVIVVEERKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEREKNYARKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGNGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVDDVMTPLRDCFMIASDATLDFGTMSEIMESGYTRIPVFEEERSNIVDLLFVKDLAFVDPDDSTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKRITHRERKQDFSAFKPTDNEMKVKISPQLLLATLRFLATDIEPFSLVQISEKILLRLLKHPNVIQELKFNDKNKKALEHYLYVRNKPVDYFILILQGKVEVEAGKDGMKFEAGAFSSYGMMALTASPENKSPPRPYGLNHSDSLNRSDRNEVINPPLGS--SNNQLNSFLQIYAPDYTVRAITDLLYVKVTRQQYQNALMAS 790
BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Match: cnnm2a (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:NCBI gene;Acc:103036966]) HSP 1 Score: 447.203 bits (1149), Expect = 5.086e-144 Identity = 267/610 (43.77%), Postives = 382/610 (62.62%), Query Frame = 2
Query: 440 ENFRLY-FCSKIQTNSTNSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG----------------------ESLFKKAIEDMPDVEQLFNSHND--------------IGTVISNLTKNCF---FIPDFNLTAVTNLQYLKITAKHYLFARMLS 2137
E +LY C Q + + S W+Y + E+K LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ ++ YAK I P+R +GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV+ STIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI ++ILDF+TM+EI+ +G+TR+P++EGER NI +L VKDLAF+DPDD P+ T+ FY+ + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K+R R QDFS F + ++SPQL +A LR LA+ V+ F ++ +L LL + N++ E + + E+ +F + K +Y ILILQGK E E + F+AGPF +G ESL P N H+D +G+ SN N F ++PD+++ A ++L Y+K+T + Y A M S
Sbjct: 156 EKSKLYHLCIATQDDEMRPE-SIWVYHEGHDTKVLVVEERKFLLPFWLQVIFIAMLLCLSGMFSGLNLGLMALDPMELRIVQNCGTERERNYAKYIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVASTIGIVIFGEIMPQAICSRHGLAVGANTIFLTKFFMILTFPASYPVSKLLDHVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMIIGDAILDFNTMSEIMESGYTRIPVFEGERCNIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKRIAHRERKQDFSAFKPTDNNLGVKISPQLLLATLRFLATEVEPFGPAQMSEKILLRLLKHPNVIQELKYDDKNKKMLEHYLFHRNKPVDYFILILQGKVEVEAGKEGMKFKAGPFSYYGMMALTSSPVPLSLSRTFVVSRAESLAGSPENKSPPRPFGLN-HSDSVNRNDRMEALTPTLGS--SNNQLNAFLQIYVPDYSVRAASDLLYIKVTRQQYQNALMAS 761
BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Match: cnnm2b (metal transporter CNNM2-like [Source:NCBI gene;Acc:103025617]) HSP 1 Score: 442.965 bits (1138), Expect = 8.430e-143 Identity = 259/589 (43.97%), Postives = 374/589 (63.50%), Query Frame = 2
Query: 455 YFCSKIQTNSTNSQI---SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-----NANILVEHTFK-SDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHND--------------IGTVISNLTKNCF---FIPDFNLTAVTNLQYLKITAKHYLFARMLS 2137
Y C T++ S WIY E + E+K LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YA+ I P+R +GN+LLC+LLLGNVLVN TL IL+DD+ G+GL+AV++STIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V D+MTPL D FMI+ ++ LDF TM+EI+ +G+TR+P++E ERSNI +L VKDLAF+DPDD P+ T+ FY+ + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K+R R QDFS F + ++SPQL +A LR LA+ E F + + + +L + N++ E F + E+ ++ + K +Y ILILQGK E + + FEAG F +G + E+ +H+D +G+ SN N F + PD+ + A+T+L Y+K+T + Y A M S
Sbjct: 164 YLCIATSTSAGTHDPWTESTWIYHEGEDTKVIVVEERKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEREKNYARKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGNGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVDDVMTPLRDCFMIASDATLDFGTMSEIMESGYTRIPVFEEERSNIVDLLFVKDLAFVDPDDSTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKRITHRERKQDFSAFKPTDNEMKVKISPQLLLATLRFLAT------EPFSLVQISEKILLRLLKHPNVIQELKFNDKNKKALEHYLYVRNKPVDYFILILQGKVEVEAGKDGMKFEAGAFSSYGMMALTASPENKSPPRPYGLNHSDSLNRSDRNEVINPPLGS--SNNQLNSFLQIYAPDYTVRAITDLLYVKVTRQQYQNALMAS 744
BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Match: cnnm2b (metal transporter CNNM2-like [Source:NCBI gene;Acc:103025617]) HSP 1 Score: 439.884 bits (1130), Expect = 1.311e-140 Identity = 264/604 (43.71%), Postives = 376/604 (62.25%), Query Frame = 2
Query: 455 YFCSKIQTNSTNSQI---SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTFK-SDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG----------------------ESLFKKAIEDMPDVEQLFN-----SHNDIGTVI------SNLTKNCF---FIPDFNLTAVTNLQYLKITAKHYLFARMLS 2137
Y C T++ S WIY E + E+K LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YA+ I P+R +GN+LLC+LLLGNVLVN TL IL+DD+ G+GL+AV++STIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V D+MTPL D FMI+ ++ LDF TM+EI+ +G+TR+P++E ERSNI +L VKDLAF+DPDD P+ T+ FY+ + V ++T L ML +F++GK+H+A V+R+ E +GDP+ ++G+VTLEDVIEEII++EI+DETD++TDN K+R R QDFS F + ++SPQL +A LR LA++++ F I+ +L LL + N++ E F + E+ ++ + K +Y ILILQGK E + + FEAG F +G ES P N + +D VI SN N F + PD+ + A+T+L Y+K+T + Y A M S
Sbjct: 208 YLCIATSTSAGTHDPWTESTWIYHEGEDTKVIVVEERKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEREKNYARKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGNGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVDDVMTPLRDCFMIASDATLDFGTMSEIMESGYTRIPVFEEERSNIVDLLFVKDLAFVDPDDSTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKRITHRERKQDFSAFKPTDNEMKVKISPQLLLATLRFLATDIEPFSLVQISEKILLRLLKHPNVIQELKFNDKNKKALEHYLYVRNKPVDYFILILQGKVEVEAGKDGMKFEAGAFSSYGMMALTASPVPLSLSRNCVASRSESRAGSPENKSPPRPYGLNHSDSLNRSDRNEVINPPLGSSNNQLNSFLQIYAPDYTVRAITDLLYVKVTRQQYQNALMAS 811
BLAST of Metal transporter cnnm2 vs. Ensembl Sea Lamprey
Match: cnnm4b (cyclin and CBS domain divalent metal cation transport mediator 4b [Source:ZFIN;Acc:ZDB-GENE-070705-181]) HSP 1 Score: 383.259 bits (983), Expect = 6.860e-121 Identity = 245/639 (38.34%), Postives = 369/639 (57.75%), Query Frame = 2
Query: 392 SDYIATVKVKIDTVWK-ENFRL-YFCSKIQTNSTNSQIS-QWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRL--VRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQ--GKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMP---DVEQLFNSHNDIGTVISNLTKNCF------------------------------------FIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAP 2164
++Y V+V + ++ K E RL Y C+K + W+ S E+ S+LP W+QI I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I PIR++GN+LLC+LLLGNVLVN TL IL+DDL GSG++AVI ST+GIVI GEI+PQA+C+RH L +GA TI +TK FM++T S+PI KLLDV+LG+E+G VY+R +L +++ +VK+E II GAL L K V+D+MTPL D FM+S +++LDF TM+EI+++G+TR+P+YE E SN+ +L VKDLAF+DPDD P+ T+ FYN + V ++T L ML +F++G+ ++ +V ++E+ G +G++ E VI + A I + +DN K++ L R QD+S F E+ ++SPQL +A R LA+ ++ F ++ +L LL + N+ E F + + E+ +++ K +Y IL+LQ GK EV E + FE+G F FG + + +P + + + N T+ ++PD+ + AVT+LQY+KIT + Y A S +S +P
Sbjct: 92 NEYSVVVEVDVKSLRKSETERLFYLCTKGIAGPAGLETGDNWVAHMGNDSRIAMVEERTSMLPRWLQILFIAVLLCLSGMFSGLNLGLMALDPMELRIVQNCGTAKEKAYAKKIEPIRRQGNYLLCSLLLGNVLVNTTLTILLDDLIGSGVVAVIASTVGIVIFGEIVPQALCSRHGLAVGANTIVLTKLFMILTFPASFPISKLLDVVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRVKTVEDVMTPLKDCFMLSADAVLDFGTMSEIMQSGYTRIPVYEDELSNVVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGETYLRYVGKVESSGTGTSGH-FVGVLAPEQVIPVLPCAVIQGSRFLISDNKSKKKVLHRERKQDYSAFKPSESQTKIKISPQLLLATHRFLAAELEPFKPVQVSEKILLRLLKHPNVFQEIKFDEKNRKAPEHYLYQHNKPVDYFILVLQTKGKVEVEVGKEGMKFESGAFSYFGIPILTSSPPTVPYSLSRTLVLSRAESLAGSPGNATRTSLNPSPSHSLALNRSDSLNRTEPTGGSNNQLNIPLLQPYVPDYCVHAVTDLQYVKITRQQYWNAMAASKLDSSPHSP 729
BLAST of Metal transporter cnnm2 vs. Ensembl Yeast
Match: MAM3 (Protein required for normal mitochondrial morphology; has similarity to hemolysins [Source:SGD;Acc:S000005421]) HSP 1 Score: 207.223 bits (526), Expect = 3.971e-57 Identity = 139/346 (40.17%), Postives = 209/346 (60.40%), Query Frame = 2
Query: 590 IIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAK-IIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIG--SVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIY-EGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQ 1615
I IIL L G+F+GL +GLM D LK+I +GS ++K+ AK ++ I + +++L TLLL NV+ N TL I++D G G AV+ STI IVI GEIIPQ++C ++ L +GA M + ++YPI LLD +LG++ G +Y ++ L+ LV + +G + KDE II+ L L K V++IMTP+ +VF +S ++ILD T+ +I +GF+R+PI+ E +N +L V+ L DPDD +P++ F ++ NT +LN F++GKAHM V + G IG++TLEDVIEE+I EI+DE+DVF D + ++R Q
Sbjct: 67 ISIILVLLGGVFAGLTLGLMGQDEVYLKVISTSGSNSEKKLAKRVLDLISRGKHWVLVTLLLSNVITNETLPIVLDRCLGGGWQAVVSSTILIVIFGEIIPQSVCVKYGLQVGAFFCPFVLVLMYLMYPVAYPIATLLDYMLGEDHGTMYKKSGLKTLVTLHRTMGVERLTKDEVTIISAVLDLKAKRVEEIMTPIENVFTMSADTILDDKTVEKIFNSGFSRIPIFLPNEPNNFIGMLLVRVLISYDPDDCLPIS---HFPLATLPETSPNTSCLNILNYFQEGKAHMCVVSKEPGSSHG-----AIGVLTLEDVIEELIGEEIVDESDVFVD---MHQHIMRQQ 401
BLAST of Metal transporter cnnm2 vs. Ensembl Nematostella
Match: EDO48694 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIF4]) HSP 1 Score: 384.8 bits (987), Expect = 8.890e-124 Identity = 223/509 (43.81%), Postives = 325/509 (63.85%), Query Frame = 2
Query: 647 MALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKN-CFFIPDFNLTAVTNLQYLKITAKHYLFAR---MLSIWQNSDLA 2161
MALD TELKI+ +GS ++++YAK I PIR+ GN+LLCTLL GNVLVN + +L+D L G+G++AV+ ST GIVI GEI+PQ++C+RH L +GA TIWITK FM +T LSYPI ++LD +LGKELG +Y++ QL ++K + +DE II+GAL K V+++MT L D F+++VNS LDF TM I+++G +R+P+YE ER N+ +L VKDLAF+DPDD P+ TV FYN + V D+T L +L +F++ +H+A VER+ +GDP+ IG+VTLED++EEIIQ+EI+DETDV+ DN + R DF+ F+ + + ++SPQL +A ++L++ V F ED I+ VL+ L+ +I+ E D E ++K+G A++ +LILQGK V E +FE GPF FG L NS N I TK ++PD+ + A+++L Y+K+ Y A+ M+ Q ++L
Sbjct: 1 MALDPTELKIVINSGSPSEQKYAKKIDPIRRHGNYLLCTLLFGNVLVNTSFTVLLDSLIGNGIVAVLGSTAGIVIFGEIVPQSVCSRHGLKVGATTIWITKIFMFLTFPLSYPISRILDCVLGKELGTIYNKKQLLEMIKVTDEYNDLEEDEMNIISGALNYRNKTVQEVMTRLEDCFLVNVNSALDFRTMAWIMQSGHSRIPVYEDERHNVVGLLFVKDLAFVDPDDCTPLQTVIKFYNHPVQRVFDDTHLDVLLEEFKKKHSHLAIVERVNDTGEGDPFYEAIGIVTLEDILEEIIQSEIVDETDVYLDNKSGKVVPGRKPDFAFFS--QDRERVKISPQLALAVFQYLSTAVDVFHEDIISTAVLKRLIEQDIITEIQLGDKSDKKEVYLYKRGTPADFFVLILQGKVEVNVGQEQFVFEEGPFTHFGGM-------------ALVNSSN-----IHGSTKTLAQYVPDYTVRAMSDLTYIKVPRAMYWRAKRATMMERQQGTELG 489
BLAST of Metal transporter cnnm2 vs. Ensembl Nematostella
Match: EDO30992 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZ75]) HSP 1 Score: 202.601 bits (514), Expect = 4.144e-57 Identity = 133/353 (37.68%), Postives = 206/353 (58.36%), Query Frame = 2
Query: 575 WMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLV---KEQQLIGS--VVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPY-RVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQ 1615
W+ + + + L +GL SGL +GL++LDI LK++ + G N++++AK I P+ ++ + LL TLLL N + I MD ++ S ++A+ VS ++ GE++PQA+C R+ L IGA K +++ I+++PI KLLD +LG E + RA+L+ LV KE + DE LII GAL + K ++D TPL FM+SV+ LD M +I+ G +RVP+YEG R NI ++ VK L +DP D V V + S+L + L +L+ F+ GK+HM V + GD + +G++TLEDV+E++IQ +I DETD V++ R V+NQ
Sbjct: 35 WIYLGVYVFLVLFAGLMSGLTMGLLSLDILSLKVLMRGGKINERKHAKKILPLVEQHHLLLVTLLLANAAAVEAMPIFMDRIS-SPVIAICVSVTAVLFFGEVVPQALCTRYGLAIGACMAPFVKILIILLFIVAWPISKLLDCLLGNEHSTFFRRAELKELVDLHKEGTDANEEPLRDDEVLIIQGALDMRNKRIRDRYTPLDRTFMLSVDDKLDDSLMLKIIAKGHSRVPVYEGSRENIVGLILVKSLIRLDPKDATLVRGVYRPRDGSLLASHVDEPLFELLDKFQTGKSHMCVV---YGKAVGDVIGKRTLGIITLEDVLEQLIQEDIWDETD-----VRQIRPHVQNQ 378
BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Match: cnnm4b (metal transporter CNNM4 [Source:NCBI gene;Acc:105354685]) HSP 1 Score: 442.195 bits (1136), Expect = 2.059e-142 Identity = 259/564 (45.92%), Postives = 376/564 (66.67%), Query Frame = 2
Query: 551 EKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQ---DFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSH----NDIGTVISNLTKNCF-----------------FIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAP 2164
E KSLLP+W+Q+ +I +L LSG+FSGLN+GLMALD EL+I++ G+ +KRYA+ I PIR +GN+LLC+LLLGNVLVN TL IL+DDL GSGL AV+ ST+GIVI GEI+PQA+C+RH L +GA TI +TK FM++T LS+PI KLLD +LG+E+G VY+R +L ++K + +VK+E +I GAL L TK V+D+MTPL+D FMI +++LDF+TM+EI+ +G+TR+P+YEGERSNI +L VKDLAF+DPDD + T+ FYN + V +T L +ML +F++GK+H+A V+++ E +GDP+ ++GLVTLEDVIEEII++EI+DE+D++TDN + ++++ N+ DFS F K ++SPQL +AA R LA+ V F ++ I+ VL +L + +++ E F ++D + I++KGK +Y ILILQG+ E E++ FE GPF +G P +E SH N ++ C + PDFN+ A+++LQ++KIT Y M S+ +S +P
Sbjct: 174 EAKSLLPIWLQVILISLLLVLSGMFSGLNLGLMALDPMELRIVQSCGTDKEKRYARKIEPIRSKGNYLLCSLLLGNVLVNTTLTILLDDLIGSGLGAVVASTVGIVIFGEIVPQALCSRHGLAVGANTIMLTKLFMLLTFPLSWPISKLLDCVLGQEIGTVYNREKLVGMLKVTEPYNDLVKEELNMIQGALELRTKTVEDVMTPLNDCFMIHSDAVLDFNTMSEIMESGYTRIPVYEGERSNIMDILYVKDLAFVDPDDCTTLKTITKFYNHPVHFVFHDTKLDSMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDLYTDN-RSRKKVAPNKNKRDFSAFKHESESKV-KISPQLLLAAHRFLATEVSVFLQNQISDKVLLRILRHPDVVQEIKFNENDKRSLHHYIYQKGKPVDYFILILQGRVEVEAGNENMKFETGPFSYYGVMALSA-----PTLEFRSPSHLSGLNRTSSLSGADRSECLSVSGSNSQLNNSLPLQQYTPDFNVRALSDLQFVKITRAQYQNGLMASLLDSSPQSP 730
BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Match: cnnm4b (metal transporter CNNM4 [Source:NCBI gene;Acc:105354685]) HSP 1 Score: 434.876 bits (1117), Expect = 2.161e-139 Identity = 261/580 (45.00%), Postives = 380/580 (65.52%), Query Frame = 2
Query: 551 EKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQ---DFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFG-ESLFKKAIEDMPDVE-------QLFN--------SH----NDIGTVISNLTKNCF-----------------FIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAP 2164
E KSLLP+W+Q+ +I +L LSG+FSGLN+GLMALD EL+I++ G+ +KRYA+ I PIR +GN+LLC+LLLGNVLVN TL IL+DDL GSGL AV+ ST+GIVI GEI+PQA+C+RH L +GA TI +TK FM++T LS+PI KLLD +LG+E+G VY+R +L ++K + +VK+E +I GAL L TK V+D+MTPL+D FMI +++LDF+TM+EI+ +G+TR+P+YEGERSNI +L VKDLAF+DPDD + T+ FYN + V +T L +ML +F++GK+H+A V+++ E +GDP+ ++GLVTLEDVIEEII++EI+DE+D++TDN + ++++ N+ DFS F K ++SPQL +AA R LA+ V F ++ I+ VL +L + +++ E F ++D + I++KGK +Y ILILQG+ E E++ FE GPF +G +L + P LF+ SH N ++ C + PDFN+ A+++LQ++KIT Y M S+ +S +P
Sbjct: 174 EAKSLLPIWLQVILISLLLVLSGMFSGLNLGLMALDPMELRIVQSCGTDKEKRYARKIEPIRSKGNYLLCSLLLGNVLVNTTLTILLDDLIGSGLGAVVASTVGIVIFGEIVPQALCSRHGLAVGANTIMLTKLFMLLTFPLSWPISKLLDCVLGQEIGTVYNREKLVGMLKVTEPYNDLVKEELNMIQGALELRTKTVEDVMTPLNDCFMIHSDAVLDFNTMSEIMESGYTRIPVYEGERSNIMDILYVKDLAFVDPDDCTTLKTITKFYNHPVHFVFHDTKLDSMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDLYTDN-RSRKKVAPNKNKRDFSAFKHESESKV-KISPQLLLAAHRFLATEVSVFLQNQISDKVLLRILRHPDVVQEIKFNENDKRSLHHYIYQKGKPVDYFILILQGRVEVEAGNENMKFETGPFSYYGVMALSAPTLVAAPRPRLLSFKRFSLFSRLPEFRSPSHLSGLNRTSSLSGADRSECLSVSGSNSQLNNSLPLQQYTPDFNVRALSDLQFVKITRAQYQNGLMASLLDSSPQSP 751
BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Match: cnnm4a (metal transporter CNNM4 [Source:NCBI gene;Acc:101158782]) HSP 1 Score: 431.409 bits (1108), Expect = 6.517e-139 Identity = 248/546 (45.42%), Postives = 368/546 (67.40%), Query Frame = 2
Query: 551 EKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQ---DFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCF----------------------FIPDFNLTAVTNLQYLKITA 2107
EKKS+LPLW+Q+ +I L LSG+FSGLN+GLMALD EL+I++ G+ +KRYA+ I PIR +GN+LLC+LLLGNVLVN TL IL+DDL GSGL AV+ ST+GIVI GEI+PQA+C+RH L +GA TI +TKFFM++T LS+P+ KLLDV+LG+E+G VY+R +L +++ + + K+E +I GAL L +K V+D+MTPL++ FMI +++LDF+TM+EI+ +G+TR+P+Y+ ER+NI +L VKDLAF+DPDD + T+ FYN + V +T L ML +F++GK+H+A V+++ E +GDP+ ++GLVTLEDVIEEII++EI+DE+D++TDN + +++ N+ DFS F + ++SPQL +AA R LA+ V F I VL +L + +++ E F +SD ++ ++++GK +Y ILILQG+ E E++ FE GPF +G P +E F S + G + + + +C +IPDF++ A+T+LQY+K+ A
Sbjct: 169 EKKSMLPLWLQVILICGLLVLSGMFSGLNLGLMALDPMELRIVQSCGTDKEKRYARKIEPIRSKGNYLLCSLLLGNVLVNTTLTILLDDLIGSGLGAVVASTVGIVIFGEIVPQALCSRHGLAVGANTIMVTKFFMLLTFPLSFPVSKLLDVLLGQEIGTVYNREKLVGMLRVTEPYNDLDKEELNMIQGALELRSKTVEDVMTPLANCFMIQADAVLDFNTMSEIMESGYTRIPVYDEERTNIVDILYVKDLAFVDPDDCTNLKTITKFYNHPVHFVFHDTKLDAMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDLYTDN-RNNKKVDSNKNKRDFSAF---KHDIKLKISPQLMLAAHRFLATEVNLFSPFQIKEKVLLRILRHPDVIQELKFNESDKRSPQHFLYQRGKPVDYFILILQGRVEVEAGNENMKFETGPFSYYGVMALS-----TPSLE--FRSPSHGGNLNRSASLSCTERAQESGSISGSQPQIPGTPFQYIPDFSVRALTDLQYVKVPA 703
BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Match: cnnm2b (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:NCBI gene;Acc:101175055]) HSP 1 Score: 430.639 bits (1106), Expect = 5.793e-138 Identity = 263/565 (46.55%), Postives = 381/565 (67.43%), Query Frame = 2
Query: 506 WIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHND--------------IGTVISNLTKNCF---FIPDFNLTAVTNLQYLKITAKHYLFARMLS 2137
WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R +GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV++STIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI ++ LDF+TM+EI+++G+TR+P++EGE+SNI +L VKDLAF+DPDD P+ T+ FY+ + V ++T L TML +F++GK+HMA V+R+ E +GDP+ ++G+VTLED+IEEII++EI+DETD++TDN K++ R QDFS F + ++SPQL +AALR LA+ V+ F ++ ++ +L LL + N++ + + ++ E+ +F + K +Y ILILQGK E E + FEAGPF +G + E+ +H+D +G+ SN N F +IPD+++ A ++LQY+K+T + Y A M S
Sbjct: 185 WIYHDGEDTKVIVVEEKKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEREKNYAKKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMIPGDTTLDFNTMSEIMKSGYTRIPVFEGEKSNIVDLLLVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDTMLEEFKKGKSHMAIVQRVNNEGEGDPFYEVLGIVTLEDIIEEIIKSEILDETDLYTDNKSKKKITHRERKQDFSAFKPSDNEMKVKISPQLLLAALRFLATEVEPFYQEQMSQKILLRLLKHPNVIQDLKYDDNNKRAPEHYLFHRNKPVDYFILILQGKVEVEAGKEGMKFEAGPFSFYGMMSLTASPENKSPPRPFGLNHSDSLNRSDRIDAITPTLGS--SNNQLNSFLHIYIPDYSVRASSDLQYIKVTRQQYQNAVMAS 747
BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Match: cnnm2b (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:NCBI gene;Acc:101175055]) HSP 1 Score: 431.024 bits (1107), Expect = 1.000e-136 Identity = 263/565 (46.55%), Postives = 381/565 (67.43%), Query Frame = 2
Query: 506 WIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQR--RLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLL-NANILVEHTF-KSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHND--------------IGTVISNLTKNCF---FIPDFNLTAVTNLQYLKITAKHYLFARMLS 2137
WIY E + EKK LLP W+Q+ I +L LSG+FSGLN+GLMALD EL+I++ G+ +K YAK I P+R +GN+LLC+LLLGNVLVN TL IL+DD+ GSGL+AV++STIGIVI GEI+PQAIC+RH L +GA TI++TKFFM++T SYP+ KLLD +LG+E+G VY+R +L +++ +VK+E II GAL L TK V+D+MTPL D FMI ++ LDF+TM+EI+++G+TR+P++EGE+SNI +L VKDLAF+DPDD P+ T+ FY+ + V ++T L TML +F++GK+HMA V+R+ E +GDP+ ++G+VTLED+IEEII++EI+DETD++TDN K++ R QDFS F + ++SPQL +AALR LA+ V+ F ++ ++ +L LL + N++ + + ++ E+ +F + K +Y ILILQGK E E + FEAGPF +G + E+ +H+D +G+ SN N F +IPD+++ A ++LQY+K+T + Y A M S
Sbjct: 283 WIYHDGEDTKVIVVEEKKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEREKNYAKKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMIPGDTTLDFNTMSEIMKSGYTRIPVFEGEKSNIVDLLLVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDTMLEEFKKGKSHMAIVQRVNNEGEGDPFYEVLGIVTLEDIIEEIIKSEILDETDLYTDNKSKKKITHRERKQDFSAFKPSDNEMKVKISPQLLLAALRFLATEVEPFYQEQMSQKILLRLLKHPNVIQDLKYDDNNKRAPEHYLFHRNKPVDYFILILQGKVEVEAGKEGMKFEAGPFSFYGMMSLTASPENKSPPRPFGLNHSDSLNRSDRIDAITPTLGS--SNNQLNSFLHIYIPDYSVRASSDLQYIKVTRQQYQNAVMAS 845
BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Match: SMESG000047046.1 (SMESG000047046.1) HSP 1 Score: 1573.91 bits (4074), Expect = 0.000e+0 Identity = 811/813 (99.75%), Postives = 813/813 (100.00%), Query Frame = 2
Query: 62 MSQXXXXXXXXXXXXXNPYSFQEVNSKSSEKIDNSIIPIIIGYKNKNKNSRWSSDLPSIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSKIQTNSTNSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGTIDQINYAPIHANESLGSLALRNKKSITTTSMQLMRDFYQREWEKYIEPNESGDDAMNFNIQVPDENSSLIENKSQSEIRSVKINIDQRKNEEILNEELSTSNRFLHKC 2500
MSQISIWIALIIIYCINPYSFQEVNSKSSEKIDNSIIPIIIGYKNKNKNSRWSSDLPSIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSKIQTNSTNSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRGNFLLCTLLLGNVLVNNTLAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCED+ITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGTIDQINYAPIHANESLGSLALRNKKSITTTSMQLMRDFYQREWEKYIEPNESGDDAMNFNIQVPDENSSLIENKSQSEIRSVKINID+RKNEEILNEELSTSNRFLHKC
Sbjct: 1 MSQISIWIALIIIYCINPYSFQEVNSKSSEKIDNSIIPIIIGYKNKNKNSRWSSDLPSIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSKIQTNSTNSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRGNFLLCTLLLGNVLVNNTLAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDYITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGTIDQINYAPIHANESLGSLALRNKKSITTTSMQLMRDFYQREWEKYIEPNESGDDAMNFNIQVPDENSSLIENKSQSEIRSVKINIDERKNEEILNEELSTSNRFLHKC 813
BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Match: SMESG000070597.1 (SMESG000070597.1) HSP 1 Score: 532.717 bits (1371), Expect = 9.461e-179 Identity = 317/652 (48.62%), Postives = 439/652 (67.33%), Query Frame = 2
Query: 233 SIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSKIQTNST-NSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGTIDQ 2185
+++ IP++ + LYG L++V ++F+ ++ CD R T ++PVT + T + KE F Y C + N T NS W +Q + + + +EK +LP+ GLN+GLM+L I +L + AGS +K+YAKII PIR GNFLL TLLLGNVLVN+TL IL+DD TG+GL+AVI ST+GIVILGEIIPQ++ +R+AL IGAKT+WITK FM++T ++S+PIGK+LD +LGKELG VYSR +LE+LVK+QQL+G+VVKDE II GAL LTTK KDIMT L + FMI +S+L+FD +N+IVRNGFTR+P+YEGER+NIKAVLN+KDL +DPDD IPV TVC+FY R I+ V T LR ML +F++GK H+AFV + D +IGLVTLEDVIEEIIQAEI+DETD++TDN ++ RR + QDFS+F+ E+ + +L+PQLK+ AL+HL + + F ED I+ NVL+SLLNANI++E + + ++ N I K K N+AIL+L G+ VS E+L FE+GPF+ FGE++ KK E P ++ + + ++ C FIPD+++ A++N+QYL I +HY+FAR LS + +P I++
Sbjct: 13 NVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKF-FYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEK--MLPIC-----------------GLNLGLMSLSINDLHLFIAAGSPQEKKYAKIIAPIRNHGNFLLATLLLGNVLVNSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQ---IIGLVTLEDVIEEIIQAEIIDETDIYTDNEQRTRRSLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEIISFREDLISFNVLKSLLNANIVIEVKY-NPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILKKINEVFPTIDL---KKDQLPSLAEKAKSKCCFIPDYSVLALSNVQYLIIKIEHYIFARYLSQRKIDSHSPSNKNINR 635
BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Match: SMESG000070597.1 (SMESG000070597.1) HSP 1 Score: 532.717 bits (1371), Expect = 1.272e-178 Identity = 317/652 (48.62%), Postives = 439/652 (67.33%), Query Frame = 2
Query: 233 SIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSKIQTNST-NSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGTIDQ 2185
+++ IP++ + LYG L++V ++F+ ++ CD R T ++PVT + T + KE F Y C + N T NS W +Q + + + +EK +LP+ GLN+GLM+L I +L + AGS +K+YAKII PIR GNFLL TLLLGNVLVN+TL IL+DD TG+GL+AVI ST+GIVILGEIIPQ++ +R+AL IGAKT+WITK FM++T ++S+PIGK+LD +LGKELG VYSR +LE+LVK+QQL+G+VVKDE II GAL LTTK KDIMT L + FMI +S+L+FD +N+IVRNGFTR+P+YEGER+NIKAVLN+KDL +DPDD IPV TVC+FY R I+ V T LR ML +F++GK H+AFV + D +IGLVTLEDVIEEIIQAEI+DETD++TDN ++ RR + QDFS+F+ E+ + +L+PQLK+ AL+HL + + F ED I+ NVL+SLLNANI++E + + ++ N I K K N+AIL+L G+ VS E+L FE+GPF+ FGE++ KK E P ++ + + ++ C FIPD+++ A++N+QYL I +HY+FAR LS + +P I++
Sbjct: 22 NVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKF-FYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEK--MLPIC-----------------GLNLGLMSLSINDLHLFIAAGSPQEKKYAKIIAPIRNHGNFLLATLLLGNVLVNSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQ---IIGLVTLEDVIEEIIQAEIIDETDIYTDNEQRTRRSLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEIISFREDLISFNVLKSLLNANIVIEVKY-NPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILKKINEVFPTIDL---KKDQLPSLAEKAKSKCCFIPDYSVLALSNVQYLIIKIEHYIFARYLSQRKIDSHSPSNKNINR 644
BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Match: SMESG000070597.1 (SMESG000070597.1) HSP 1 Score: 532.332 bits (1370), Expect = 3.295e-178 Identity = 317/652 (48.62%), Postives = 439/652 (67.33%), Query Frame = 2
Query: 233 SIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSKIQTNST-NSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLSIWQNSDLAPYKGTIDQ 2185
+++ IP++ + LYG L++V ++F+ ++ CD R T ++PVT + T + KE F Y C + N T NS W +Q + + + +EK +LP+ GLN+GLM+L I +L + AGS +K+YAKII PIR GNFLL TLLLGNVLVN+TL IL+DD TG+GL+AVI ST+GIVILGEIIPQ++ +R+AL IGAKT+WITK FM++T ++S+PIGK+LD +LGKELG VYSR +LE+LVK+QQL+G+VVKDE II GAL LTTK KDIMT L + FMI +S+L+FD +N+IVRNGFTR+P+YEGER+NIKAVLN+KDL +DPDD IPV TVC+FY R I+ V T LR ML +F++GK H+AFV + D +IGLVTLEDVIEEIIQAEI+DETD++TDN ++ RR + QDFS+F+ E+ + +L+PQLK+ AL+HL + + F ED I+ NVL+SLLNANI++E + + ++ N I K K N+AIL+L G+ VS E+L FE+GPF+ FGE++ KK E P ++ + + ++ C FIPD+++ A++N+QYL I +HY+FAR LS + +P I++
Sbjct: 43 NVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKF-FYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEK--MLPIC-----------------GLNLGLMSLSINDLHLFIAAGSPQEKKYAKIIAPIRNHGNFLLATLLLGNVLVNSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQ---IIGLVTLEDVIEEIIQAEIIDETDIYTDNEQRTRRSLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEIISFREDLISFNVLKSLLNANIVIEVKY-NPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILKKINEVFPTIDL---KKDQLPSLAEKAKSKCCFIPDYSVLALSNVQYLIIKIEHYIFARYLSQRKIDSHSPSNKNINR 665
BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Match: SMESG000023862.1 (SMESG000023862.1) HSP 1 Score: 444.891 bits (1143), Expect = 3.820e-145 Identity = 258/546 (47.25%), Postives = 368/546 (67.40%), Query Frame = 2
Query: 500 SQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRXXXXXXXXXXXXXXXXXXXAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDFITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFKKAIEDMPDVEQLFNSHNDIGTVISNLTKNCFFIPDFNLTAVTNLQYLKITAKHYLFARMLS 2137
QW++Q +E + T +T +P W+ I +I+ F S FSG+N+GLM L + LK ++AG+T +K+YAK I PIRK GN LLCT+L GNVL N++L I M L + ++ + +TIGIVI GEI+PQA AR+AL TI +T ++++ LSYP+GK LD ++G+E+ Q YSR +L+ ++ EQ+ +G V KDE IIAGALTLT K V D+MTP+S VFMIS N+ILD+ TM EIVRNG+TR+P+Y+ +++NIK VLN+KDL FIDP D IPV+T+CTFY+R ILIVP + L +LN+F++GKAH+AF+E++ DGDP++ LIGLVTLEDVIEEIIQ EI+DETD+F +NV ++++++ N+ + N+ T L PQL A L+++A ++ F E FI+ +VL+SLL++ I+ H F S S NVI G+ AIL+LQG S E L+F GPF++FGE + K + + + N D +I F+ D+++T++ NLQYL I+A Y+ R LS
Sbjct: 90 GQWLHQGTEKTKTLKT-NHNIYIPKWLLIVGVIVCFGFSSFFSGINMGLMTLQPSTLKFFKEAGNTKEKKYAKAIYPIRKHGNILLCTILFGNVLANSSLTIFMSHLIKNPVVTLFTATIGIVIFGEILPQAFGARNALTFSYYTINLTILCIILSFFLSYPLGKFLDWVMGEEINQPYSREKLKQIMIEQERLGLVYKDEMEIIAGALTLTEKTVADVMTPISHVFMISFNAILDYKTMKEIVRNGYTRIPVYDVDKNNIKGVLNIKDLLFIDPQDNIPVSTICTFYDRQILIVPHDVKLPEILNEFKKGKAHLAFIEKVINAEDGDPFQKLIGLVTLEDVIEEIIQDEIIDETDMFYNNVMREKKIM-NRGATFENLHSTSNQQNLPPQLYEATLQYMAKSIHSFNEKFISYSVLKSLLHSKIVCNH-FHSLDKPSSNVIISMGEHTTKAILLLQGSVSVVTSSEGLIFVGGPFMMFGEGILKSINAYLNETKFKNNVLKDAKAIIEKFQ----FVSDYSVTSLMNLQYLSISAPQYVLIRYLS 628 The following BLAST results are available for this feature:
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Metal transporter cnnm2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 4
BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Metal transporter cnnm2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Metal transporter cnnm2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Metal transporter cnnm2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Metal transporter cnnm2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30004577 ID=SMED30004577|Name=Metal transporter cnnm2|organism=Schmidtea mediterranea sexual|type=transcript|length=2629bpback to top protein sequence of SMED30004577-orf-1 >SMED30004577-orf-1 ID=SMED30004577-orf-1|Name=SMED30004577-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=814bp MSQISIWIALIIIYCINPYSFQEVNSKSSEKIDNSIIPIIIGYKNKNKNSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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