Tyrosine-protein kinase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30004557 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283]) HSP 1 Score: 328.561 bits (841), Expect = 2.206e-105 Identity = 191/460 (41.52%), Postives = 266/460 (57.83%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + T +G IP NYV D + Y+ +TR ESERLL N GT+L+R + K LSV + N+ H+ I+ D +YI ++FN++ L+ +Y K + LT P + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK + G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLAHSLSTGQTGYIPSNYV-APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPP---------ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQ 531
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283]) HSP 1 Score: 328.561 bits (841), Expect = 2.206e-105 Identity = 191/460 (41.52%), Postives = 266/460 (57.83%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + T +G IP NYV D + Y+ +TR ESERLL N GT+L+R + K LSV + N+ H+ I+ D +YI ++FN++ L+ +Y K + LT P + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK + G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLAHSLSTGQTGYIPSNYV-APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPP---------ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQ 531
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283]) HSP 1 Score: 328.561 bits (841), Expect = 2.206e-105 Identity = 191/460 (41.52%), Postives = 266/460 (57.83%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + T +G IP NYV D + Y+ +TR ESERLL N GT+L+R + K LSV + N+ H+ I+ D +YI ++FN++ L+ +Y K + LT P + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK + G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLAHSLSTGQTGYIPSNYV-APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPP---------ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQ 531
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283]) HSP 1 Score: 326.635 bits (836), Expect = 1.278e-104 Identity = 191/465 (41.08%), Postives = 266/465 (57.20%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATE-----DIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L D+ +W+ A + T +G IP NYV D + Y+ +TR ESERLL N GT+L+R + K LSV + N+ H+ I+ D +YI ++FN++ L+ +Y K + LT P + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK + G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYV-APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPP---------ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQ 537
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: HCK (HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840]) HSP 1 Score: 321.242 bits (822), Expect = 4.568e-103 Identity = 191/464 (41.16%), Postives = 269/464 (57.97%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVP-LPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEEQ 1577
++ ALY Y+ + LSF D + E+ W+ A + T+ G IP NYV V D + ++ ++R ++ER L N+ G+++IR + K +LSVR + H+ I+ D +YI S F+ + +L+D YKK L+VP + P + E+ R + K LG G FGEVW A + + VA+K ++ MS E FL EA VM L+H K+V+L V T+ +PIYIITEFM G LL LKS G KLID AQI+EGMA++E + Y+HRDLRAANILV A+ + K+ADFGLARV++ +E YTA E +KFP++WTAPEA+ +G+F+ KSDVWSFGIL+ EIVTYG +PY MS EV+ + +R YR+ P C LYN+MM CW + E RPTF ++Q L ++ + E QY++Q
Sbjct: 60 IVVALYDYEAIHHEDLSFQKGDQMVVLEE--SGEWWKARSLATRKEGYIPSNYVARV-DSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTK--VAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTK---EPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRAL-ERGYRMPRPEN---------CPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQ 503
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-2 (Tyrosine protein-kinase src-2 [Source:UniProtKB/Swiss-Prot;Acc:O45539]) HSP 1 Score: 279.256 bits (713), Expect = 3.518e-87 Identity = 168/453 (37.09%), Postives = 253/453 (55.85%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYV--REVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQWYIIIDSK-FNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQF----QEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSN 1541
AL+ Y + LSF +DIL D G +W+ A +K T +G IP NYV + ++ P Y+ + R ++E+ L N G +L+R S + +LSVR S + H+ I+ D Y I + F + DLI Y++ L P +++ P + EV R + I+ +G G FGEVW+ +W + VA+K +++ FL EA++M KLRHPK++ L VCT+ ++PI I+TE M +LL+ L+ + GR +L++I AQ++ GMAYLE ++HRDL A NIL++ + VK+ADFGLAR+L ++ E ++FP++WTAPEA Y F+TKSDVWSFGIL+ EIVT+G +PY M+ EVL ++ YR+ P G C LY++M CW + + RPTF LQ++L +
Sbjct: 64 ALFQYDARTDDDLSFKKDDILEILNDTQG-DWWFARHKATGRTGYIPSNYVAREKSIESQPW---YFGKMRRIDAEKCLLHTLNEHGAFLVRDSESRQHDLSLSVRENDS-----VKHYRIRQLDHGGYFIARRRPFATLHDLIAHYQREADGLCVNLGAPCAKSEAPQTTTFTYDDQWEVDRRSVRLIRQIGAGQFGEVWEGRWNV--NVPVAVKKLKAGTADPTDFLAEAQIMKKLRHPKLLSLYAVCTR--DEPILIVTELM-QENLLTFLQRR-GRQCQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILINNSLSVKIADFGLARILMKENEYEARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTEIVTFGRLPYPGMTNAEVLQQVDA-GYRMPCPAG---------CPVTLYDIMQQCWRSDPDKRPTFETLQWKLED 491
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56]) HSP 1 Score: 277.33 bits (708), Expect = 7.699e-87 Identity = 174/473 (36.79%), Postives = 256/473 (54.12%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYV--REVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVR-VLGSGNVWNIHHFIIQH--NDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPR--NQNPPIQF---QEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANF----MVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAVY-GTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLY-NLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
L ALY Y + LSF D +Y D +W+ ++RT +G +P N+V ++ ++ S Y + R +ERL+ GT+LIR +D + AL++R N + H+ I+ +D+ ++I F ++ +L+ +Y P LT P PR P + Q E+ RN + LG G FGEVW KW RG VAIK ++ MS E FL EA++M + HP +V+L VCT+ E P YIITE+M NG LL L++ G + + L+D+ AQI+ GM YLE + VHRDL A N+LV +VKVADFGLAR L +++ +KFP++WTAPEA G F+ KSDVWS+GIL+YEI+T G +PY M +EV++++ + YR+ P G C +Y +++ CW + RPTF L + ++ VS +P Y
Sbjct: 19 TLVALYPYDSRADGDLSFQKGDAMYLL-DHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIE---SEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKW--RGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREE--PFYIITEYMINGSLLQYLRTD-GSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQV-ELGYRMPMPRG---------CPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNY 472
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56]) HSP 1 Score: 277.715 bits (709), Expect = 2.410e-86 Identity = 174/473 (36.79%), Postives = 256/473 (54.12%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYV--REVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVR-VLGSGNVWNIHHFIIQH--NDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPR--NQNPPIQF---QEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANF----MVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAVY-GTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLY-NLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
L ALY Y + LSF D +Y D +W+ ++RT +G +P N+V ++ ++ S Y + R +ERL+ GT+LIR +D + AL++R N + H+ I+ +D+ ++I F ++ +L+ +Y P LT P PR P + Q E+ RN + LG G FGEVW KW RG VAIK ++ MS E FL EA++M + HP +V+L VCT+ E P YIITE+M NG LL L++ G + + L+D+ AQI+ GM YLE + VHRDL A N+LV +VKVADFGLAR L +++ +KFP++WTAPEA G F+ KSDVWS+GIL+YEI+T G +PY M +EV++++ + YR+ P G C +Y +++ CW + RPTF L + ++ VS +P Y
Sbjct: 75 TLVALYPYDSRADGDLSFQKGDAMYLL-DHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIE---SEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKW--RGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREE--PFYIITEYMINGSLLQYLRTD-GSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQV-ELGYRMPMPRG---------CPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNY 528
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56]) HSP 1 Score: 277.715 bits (709), Expect = 2.410e-86 Identity = 174/473 (36.79%), Postives = 256/473 (54.12%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYV--REVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVR-VLGSGNVWNIHHFIIQH--NDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPR--NQNPPIQF---QEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANF----MVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAVY-GTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLY-NLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
L ALY Y + LSF D +Y D +W+ ++RT +G +P N+V ++ ++ S Y + R +ERL+ GT+LIR +D + AL++R N + H+ I+ +D+ ++I F ++ +L+ +Y P LT P PR P + Q E+ RN + LG G FGEVW KW RG VAIK ++ MS E FL EA++M + HP +V+L VCT+ E P YIITE+M NG LL L++ G + + L+D+ AQI+ GM YLE + VHRDL A N+LV +VKVADFGLAR L +++ +KFP++WTAPEA G F+ KSDVWS+GIL+YEI+T G +PY M +EV++++ + YR+ P G C +Y +++ CW + RPTF L + ++ VS +P Y
Sbjct: 75 TLVALYPYDSRADGDLSFQKGDAMYLL-DHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIE---SEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKW--RGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREE--PFYIITEYMINGSLLQYLRTD-GSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQV-ELGYRMPMPRG---------CPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNY 528
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56]) HSP 1 Score: 277.715 bits (709), Expect = 2.592e-86 Identity = 174/473 (36.79%), Postives = 256/473 (54.12%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYV--REVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVR-VLGSGNVWNIHHFIIQH--NDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPR--NQNPPIQF---QEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANF----MVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAVY-GTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLY-NLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
L ALY Y + LSF D +Y D +W+ ++RT +G +P N+V ++ ++ S Y + R +ERL+ GT+LIR +D + AL++R N + H+ I+ +D+ ++I F ++ +L+ +Y P LT P PR P + Q E+ RN + LG G FGEVW KW RG VAIK ++ MS E FL EA++M + HP +V+L VCT+ E P YIITE+M NG LL L++ G + + L+D+ AQI+ GM YLE + VHRDL A N+LV +VKVADFGLAR L +++ +KFP++WTAPEA G F+ KSDVWS+GIL+YEI+T G +PY M +EV++++ + YR+ P G C +Y +++ CW + RPTF L + ++ VS +P Y
Sbjct: 79 TLVALYPYDSRADGDLSFQKGDAMYLL-DHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIE---SEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKW--RGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREE--PFYIITEYMINGSLLQYLRTD-GSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQV-ELGYRMPMPRG---------CPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNY 532
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100508) HSP 1 Score: 310.071 bits (793), Expect = 2.162e-98 Identity = 178/468 (38.03%), Postives = 272/468 (58.12%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYY-NVTRGESERLLQVMSNISGTYLIRPCS-DKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQ------NPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEA-VYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEE 1574
V+ ALY Y++ + + LSF D + +D +W+ +N T+ G+IP N+V E + S ++ ++++ NV R E+++LL N GT+L+RP + + +LSV+ G +++ H+ I+ D +YI + F ++ L+ Y K + + L+ P P+ Q P ++ + E+ R+ ++ LG+G FGEV+ KW R S VA+K ++ MS FL EA +M K RH ++V L VC+Q E PIYI+ E+M G LL L+ GR F+ LI I Q++ GM YLESK +HRDL A N+L+ N + K+ DFGLARV+ D+E S+FPV+WTAPEA +YG FS KSDVWS+GIL+ E+ TYG +PY M ++EV++ I +R +R+ P F N+ Y L++ CW A E RPTF FL + ++ V++E Y E
Sbjct: 99 VVVALYDYKSRDESDLSFMKGDRMEVIDD-TESDWWRVVNLTTRQEGLIPLNFVAE--ERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSRPCPKPQPQMWDLGPELR-DKYEIPRSEIQLLRKLGRGNFGEVFYGKW--RNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEE--PIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVI-ADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENI-ERGFRMPKPTNHYFPDNI-------YQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYRE 549
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100505) HSP 1 Score: 310.071 bits (793), Expect = 2.162e-98 Identity = 178/468 (38.03%), Postives = 272/468 (58.12%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYY-NVTRGESERLLQVMSNISGTYLIRPCS-DKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQ------NPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEA-VYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEE 1574
V+ ALY Y++ + + LSF D + +D +W+ +N T+ G+IP N+V E + S ++ ++++ NV R E+++LL N GT+L+RP + + +LSV+ G +++ H+ I+ D +YI + F ++ L+ Y K + + L+ P P+ Q P ++ + E+ R+ ++ LG+G FGEV+ KW R S VA+K ++ MS FL EA +M K RH ++V L VC+Q E PIYI+ E+M G LL L+ GR F+ LI I Q++ GM YLESK +HRDL A N+L+ N + K+ DFGLARV+ D+E S+FPV+WTAPEA +YG FS KSDVWS+GIL+ E+ TYG +PY M ++EV++ I +R +R+ P F N+ Y L++ CW A E RPTF FL + ++ V++E Y E
Sbjct: 99 VVVALYDYKSRDESDLSFMKGDRMEVIDD-TESDWWRVVNLTTRQEGLIPLNFVAE--ERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSRPCPKPQPQMWDLGPELR-DKYEIPRSEIQLLRKLGRGNFGEVFYGKW--RNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEE--PIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVI-ADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENI-ERGFRMPKPTNHYFPDNI-------YQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYRE 549
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100504) HSP 1 Score: 310.071 bits (793), Expect = 2.162e-98 Identity = 178/468 (38.03%), Postives = 272/468 (58.12%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYY-NVTRGESERLLQVMSNISGTYLIRPCS-DKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQ------NPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEA-VYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEE 1574
V+ ALY Y++ + + LSF D + +D +W+ +N T+ G+IP N+V E + S ++ ++++ NV R E+++LL N GT+L+RP + + +LSV+ G +++ H+ I+ D +YI + F ++ L+ Y K + + L+ P P+ Q P ++ + E+ R+ ++ LG+G FGEV+ KW R S VA+K ++ MS FL EA +M K RH ++V L VC+Q E PIYI+ E+M G LL L+ GR F+ LI I Q++ GM YLESK +HRDL A N+L+ N + K+ DFGLARV+ D+E S+FPV+WTAPEA +YG FS KSDVWS+GIL+ E+ TYG +PY M ++EV++ I +R +R+ P F N+ Y L++ CW A E RPTF FL + ++ V++E Y E
Sbjct: 99 VVVALYDYKSRDESDLSFMKGDRMEVIDD-TESDWWRVVNLTTRQEGLIPLNFVAE--ERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSRPCPKPQPQMWDLGPELR-DKYEIPRSEIQLLRKLGRGNFGEVFYGKW--RNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEE--PIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVI-ADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENI-ERGFRMPKPTNHYFPDNI-------YQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYRE 549
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0304990) HSP 1 Score: 310.071 bits (793), Expect = 2.162e-98 Identity = 178/468 (38.03%), Postives = 272/468 (58.12%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYY-NVTRGESERLLQVMSNISGTYLIRPCS-DKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQ------NPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEA-VYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEE 1574
V+ ALY Y++ + + LSF D + +D +W+ +N T+ G+IP N+V E + S ++ ++++ NV R E+++LL N GT+L+RP + + +LSV+ G +++ H+ I+ D +YI + F ++ L+ Y K + + L+ P P+ Q P ++ + E+ R+ ++ LG+G FGEV+ KW R S VA+K ++ MS FL EA +M K RH ++V L VC+Q E PIYI+ E+M G LL L+ GR F+ LI I Q++ GM YLESK +HRDL A N+L+ N + K+ DFGLARV+ D+E S+FPV+WTAPEA +YG FS KSDVWS+GIL+ E+ TYG +PY M ++EV++ I +R +R+ P F N+ Y L++ CW A E RPTF FL + ++ V++E Y E
Sbjct: 99 VVVALYDYKSRDESDLSFMKGDRMEVIDD-TESDWWRVVNLTTRQEGLIPLNFVAE--ERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSRPCPKPQPQMWDLGPELR-DKYEIPRSEIQLLRKLGRGNFGEVFYGKW--RNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEE--PIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVI-ADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENI-ERGFRMPKPTNHYFPDNI-------YQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYRE 549
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0304989) HSP 1 Score: 310.071 bits (793), Expect = 2.162e-98 Identity = 178/468 (38.03%), Postives = 272/468 (58.12%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYY-NVTRGESERLLQVMSNISGTYLIRPCS-DKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQ------NPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEA-VYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEE 1574
V+ ALY Y++ + + LSF D + +D +W+ +N T+ G+IP N+V E + S ++ ++++ NV R E+++LL N GT+L+RP + + +LSV+ G +++ H+ I+ D +YI + F ++ L+ Y K + + L+ P P+ Q P ++ + E+ R+ ++ LG+G FGEV+ KW R S VA+K ++ MS FL EA +M K RH ++V L VC+Q E PIYI+ E+M G LL L+ GR F+ LI I Q++ GM YLESK +HRDL A N+L+ N + K+ DFGLARV+ D+E S+FPV+WTAPEA +YG FS KSDVWS+GIL+ E+ TYG +PY M ++EV++ I +R +R+ P F N+ Y L++ CW A E RPTF FL + ++ V++E Y E
Sbjct: 99 VVVALYDYKSRDESDLSFMKGDRMEVIDD-TESDWWRVVNLTTRQEGLIPLNFVAE--ERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSRPCPKPQPQMWDLGPELR-DKYEIPRSEIQLLRKLGRGNFGEVFYGKW--RNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEE--PIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVI-ADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENI-ERGFRMPKPTNHYFPDNI-------YQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYRE 549
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: lyn (LYN proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-040912-7]) HSP 1 Score: 327.405 bits (838), Expect = 1.660e-105 Identity = 190/465 (40.86%), Postives = 273/465 (58.71%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTP--IIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEEQ 1577
++ ALY Y+ +A+ L F + L E+ W+ A + T+ G IP NYV E D + +Y ++TR ++ER L +N G+YLIR + K +LS+R + + + H+ I+ D +YI F++IS +I Y K + + P+ Q P E+S+++ +K LG G FGEVW A + S VA+K ++ MS E FL EA +M L+H ++V L V T+ E PIYIITE+M NG LL LKSQ G KLID AQI+EGMAY+E K Y+HRDLRAAN+LV + K+ADFGLARV++ D+ YTA E +KFP++WTAPEA+ YG+F+ KSD+WSFG+L+YEI+TYG +PY MS EV+ + +R YR+ P C LY +M +CW + E+RPTF ++Q L ++ + E QY++Q
Sbjct: 65 IVVALYPYEAIHADDLGFKKGEKLKIIEE--HGEWWKARSLTTRKEGFIPSNYVAEA-DTMETEEWFYKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSIRDVDAQGQDVVKHYKIRSLDNGGYYISPKITFSDISSMIKHYHKQSDGLCRKLDKACEKPKAQKP-WDKDAWEISKDSIKMVKKLGAGQFGEVWMAFYN--NSTKVAVKTLKPGTMSVEAFLEEANLMKTLQHDRLVRLYAVVTKTE--PIYIITEYMANGSLLDFLKSQAGSKIQLPKLIDFSAQIAEGMAYIEKKNYIHRDLRAANVLVSEMLLCKIADFGLARVIEDDQ--YTAREGAKFPIKWTAPEAINYGSFTIKSDMWSFGVLLYEIITYGKIPYPGMSNSEVMSSV-QRGYRMPRPEN---------CPVELYEIMTTCWKNKPEDRPTFDYIQSVLDDFYTATEGQYQQQ 509
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: src (v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog [Source:NCBI gene;Acc:325084]) HSP 1 Score: 327.791 bits (839), Expect = 2.575e-105 Identity = 194/462 (41.99%), Postives = 276/462 (59.74%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQF---QEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ LSF + L + G +W+ A + T SG IP NYV D + Y+ +TR +SERLL + N GT+L+R S+ +K A + VL NV N+ H+ I+ D +YI ++F+ + L++ Y++ + LT P + PP Q E+ R++ LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK +G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L+ LM++CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 89 ALYDYESRTASDLSFRKGERLQIVNNTEG-DWWLARSLTTGESGYIPSNYV-APSDSIQAEEWYFGKITRRDSERLLLNLENRRGTFLVRE-SETTKGAYCLSVLDYDNVKGLNVKHYKIRKLDSGGFYITSRTQFSTLQQLVNHYRQHADGLCHSLTDVCPVLK-PPTQGLARDAWEIPRDSLRLDVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMGQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCP---------AECPDSLHELMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQ 529
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: src (v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog [Source:NCBI gene;Acc:325084]) HSP 1 Score: 327.791 bits (839), Expect = 2.575e-105 Identity = 194/462 (41.99%), Postives = 276/462 (59.74%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQF---QEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ LSF + L + G +W+ A + T SG IP NYV D + Y+ +TR +SERLL + N GT+L+R S+ +K A + VL NV N+ H+ I+ D +YI ++F+ + L++ Y++ + LT P + PP Q E+ R++ LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK +G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L+ LM++CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 89 ALYDYESRTASDLSFRKGERLQIVNNTEG-DWWLARSLTTGESGYIPSNYV-APSDSIQAEEWYFGKITRRDSERLLLNLENRRGTFLVRE-SETTKGAYCLSVLDYDNVKGLNVKHYKIRKLDSGGFYITSRTQFSTLQQLVNHYRQHADGLCHSLTDVCPVLK-PPTQGLARDAWEIPRDSLRLDVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMGQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCP---------AECPDSLHELMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQ 529
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: src (v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog [Source:NCBI gene;Acc:325084]) HSP 1 Score: 323.553 bits (828), Expect = 1.326e-103 Identity = 194/467 (41.54%), Postives = 275/467 (58.89%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKN-----WYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQF---QEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ LSF + L + N W+ A + T SG IP NYV D + Y+ +TR +SERLL + N GT+L+R S+ +K A + VL NV N+ H+ I+ D +YI ++F+ + L++ Y++ + LT P + PP Q E+ R++ LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK +G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L+ LM++CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 89 ALYDYESRTASDLSFRKGERLQIVNNTRKLNPREGDWWLARSLTTGESGYIPSNYV-APSDSIQAEEWYFGKITRRDSERLLLNLENRRGTFLVRE-SETTKGAYCLSVLDYDNVKGLNVKHYKIRKLDSGGFYITSRTQFSTLQQLVNHYRQHADGLCHSLTDVCPVLK-PPTQGLARDAWEIPRDSLRLDVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMGQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCP---------AECPDSLHELMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQ 535
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: fynb (FYN proto-oncogene, Src family tyrosine kinase b [Source:NCBI gene;Acc:574422]) HSP 1 Score: 313.538 bits (802), Expect = 9.450e-100 Identity = 185/467 (39.61%), Postives = 275/467 (58.89%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVND---ILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNVWNIH--HFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVP----LPRNQNPPIQFQEM-EVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y+ + LSF + I+ +TE +W++A + T +G IP NYV V D + Y+ + R ++ER L N GT+LIR S+ +K A S+ + +V H H+ I+ D +YI ++F + L+ Y + L VP +PR + ++ +++ E+ R + IK LG G FGEVW W G+ VAIK ++ MS E FL EA++M KLRH K+V+L V ++ +PIYI+TE+M G LL LK GR+ L+D+ AQ++ GMAY+E Y+HRDLR+ANILV + + K+ADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+VT G +PY M+ +EVL+++ +R YR+ P C + L+ LM+ CW +E RPTF +LQ L ++ + EPQY+
Sbjct: 96 ALYDYEARTEDDLSFRKGEKFQIINSTEG----DWWDARSLTTGGTGYIPSNYVAPV-DSIQAEDWYFGKLGRKDAERQLLSTGNPRGTFLIRE-SETTKGAFSLSIRDWDDVKGDHVKHYKIRKLDSGGYYITTRAQFETLQQLVQHYTERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTW--NGNTKVAIKTLKPGTMSPESFLEEAQIMKKLRHDKLVQLYAVVSE---EPIYIVTEYMGKGSLLDFLKDGEGRALKLPNLVDMAAQVAGGMAYIERMNYIHRDLRSANILVGDSLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQV-ERGYRMQCPQD---------CPSSLHELMVQCWKKDAEERPTFEYLQAFLEDYFTATEPQYQ 539
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: cthrc1 (collagen triple helix repeat containing 1 [Source:Xenbase;Acc:XB-GENE-980161]) HSP 1 Score: 324.324 bits (830), Expect = 1.935e-104 Identity = 188/460 (40.87%), Postives = 267/460 (58.04%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + + +G IP NYV D + Y +TR E+ERLL + N GT+L+R + K LSV + N+ H+ I+ D +YI ++F+++ L+ +Y K + LT P + Q + E+ R++ LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK ++GR +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW E RPTF +LQ L ++ + EPQY+
Sbjct: 37 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLARSLSSGQTGYIPSNYVAPS-DSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDANRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPPD---------CPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQ 477
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: cthrc1 (collagen triple helix repeat containing 1 [Source:Xenbase;Acc:XB-GENE-980161]) HSP 1 Score: 323.939 bits (829), Expect = 2.413e-104 Identity = 188/460 (40.87%), Postives = 267/460 (58.04%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + + +G IP NYV D + Y +TR E+ERLL + N GT+L+R + K LSV + N+ H+ I+ D +YI ++F+++ L+ +Y K + LT P + Q + E+ R++ LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK ++GR +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW E RPTF +LQ L ++ + EPQY+
Sbjct: 39 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLARSLSSGQTGYIPSNYVAPS-DSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDANRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWN--GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPPD---------CPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQ 479
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: cthrc1 (collagen triple helix repeat containing 1 [Source:Xenbase;Acc:XB-GENE-980161]) HSP 1 Score: 323.939 bits (829), Expect = 3.084e-104 Identity = 188/460 (40.87%), Postives = 267/460 (58.04%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + + +G IP NYV D + Y +TR E+ERLL + N GT+L+R + K LSV + N+ H+ I+ D +YI ++F+++ L+ +Y K + LT P + Q + E+ R++ LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK ++GR +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW E RPTF +LQ L ++ + EPQY+
Sbjct: 44 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLARSLSSGQTGYIPSNYVAPS-DSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDANRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPPD---------CPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQ 484
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: cthrc1 (collagen triple helix repeat containing 1 [Source:Xenbase;Acc:XB-GENE-980161]) HSP 1 Score: 323.939 bits (829), Expect = 5.142e-104 Identity = 188/460 (40.87%), Postives = 267/460 (58.04%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + + +G IP NYV D + Y +TR E+ERLL + N GT+L+R + K LSV + N+ H+ I+ D +YI ++F+++ L+ +Y K + LT P + Q + E+ R++ LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK ++GR +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW E RPTF +LQ L ++ + EPQY+
Sbjct: 61 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLARSLSSGQTGYIPSNYVAPS-DSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDANRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWN--GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPPD---------CPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQ 501
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: cthrc1 (collagen triple helix repeat containing 1 [Source:Xenbase;Acc:XB-GENE-980161]) HSP 1 Score: 324.324 bits (830), Expect = 6.454e-104 Identity = 188/460 (40.87%), Postives = 267/460 (58.04%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + + +G IP NYV D + Y +TR E+ERLL + N GT+L+R + K LSV + N+ H+ I+ D +YI ++F+++ L+ +Y K + LT P + Q + E+ R++ LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK ++GR +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW E RPTF +LQ L ++ + EPQY+
Sbjct: 87 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLARSLSSGQTGYIPSNYV-APSDSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDANRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPPD---------CPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQ 527
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397]) HSP 1 Score: 326.635 bits (836), Expect = 7.034e-105 Identity = 191/460 (41.52%), Postives = 266/460 (57.83%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + T +G IP NYV D + Y+ +TR ESERLL N GT+L+R + K LSV + N+ H+ I+ D +YI ++FN++ L+ +Y K + LT P + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK + G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 90 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLAHSLSTGQTGYIPSNYV-APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPP---------ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQ 530
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397]) HSP 1 Score: 326.635 bits (836), Expect = 7.034e-105 Identity = 191/460 (41.52%), Postives = 266/460 (57.83%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + T +G IP NYV D + Y+ +TR ESERLL N GT+L+R + K LSV + N+ H+ I+ D +YI ++FN++ L+ +Y K + LT P + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK + G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 90 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLAHSLSTGQTGYIPSNYV-APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPP---------ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQ 530
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397]) HSP 1 Score: 326.635 bits (836), Expect = 7.034e-105 Identity = 191/460 (41.52%), Postives = 266/460 (57.83%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + T +G IP NYV D + Y+ +TR ESERLL N GT+L+R + K LSV + N+ H+ I+ D +YI ++FN++ L+ +Y K + LT P + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK + G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 90 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLAHSLSTGQTGYIPSNYV-APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPP---------ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQ 530
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397]) HSP 1 Score: 325.094 bits (832), Expect = 4.074e-104 Identity = 191/465 (41.08%), Postives = 266/465 (57.20%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATE-----DIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L D+ +W+ A + T +G IP NYV D + Y+ +TR ESERLL N GT+L+R + K LSV + N+ H+ I+ D +YI ++FN++ L+ +Y K + LT P + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK + G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 90 ALYDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYV-APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPP---------ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQ 536
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397]) HSP 1 Score: 325.094 bits (832), Expect = 4.074e-104 Identity = 191/465 (41.08%), Postives = 266/465 (57.20%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATE-----DIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L D+ +W+ A + T +G IP NYV D + Y+ +TR ESERLL N GT+L+R + K LSV + N+ H+ I+ D +YI ++FN++ L+ +Y K + LT P + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK + G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 90 ALYDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYV-APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPP---------ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQ 536
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P42687|SPK1_GIRTI (Tyrosine-protein kinase SPK-1 OS=Girardia tigrina OX=6162 PE=2 SV=1) HSP 1 Score: 335.495 bits (859), Expect = 7.210e-108 Identity = 182/451 (40.35%), Postives = 269/451 (59.65%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGN-VWNIHHFII---QHNDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNC-LTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAVYG-TFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYEL 1535
++KA Y Y + +SF+ +I+Y E + W + ++ G++P NYV + DGSP ++E + + R E+E+ L + GTY+IRP ++ ALSVR + + HF I Q Y + F NI LI FY+K I + LT P+P N PP+ FQ++E++R N + +G+G FG V +AKWG S+ VA K++QS E+F+ EAK+MHKLRH KIVELLGVCT+P++ P+ II E+M NG L LK+ G+ + +++ ++A+ISEGMAYLES+ VHRDLRA NILV + KVADFGL + +FP +WTAPEA F++KSDVWS+GI+++EI+T+ + PY + KEV+++++K YR+ NP + G + C +Y +M+ CW A E RPTF LQ ++
Sbjct: 37 MVKAKYKYAASGDTDISFEEKEIMYVLEQF-DEFWLKVVKQKDNKEGLVPSNYVSKQ-DGSPQSVEAWREIQRWEAEKSLMKIGLQKGTYIIRPSRKENSYALSVRDFDEKKKICIVKHFQIKTLQDEKGISYSVNIRNFPNILTLIQFYEKNGIGNTHIPLTDPMPDNYQPPVHFQDIEINRENIEILNEIGRGFFGSVHRAKWGR--SYEVAAKMLQSSKAEREKFVLEAKIMHKLRHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEYLKTPDGKKTNLNQMVHMMAEISEGMAYLESEKVVHRDLRADNILVANDLTRKVADFGLTELTDGSLGDQEKKTLRFPYKWTAPEAAKSKVFTSKSDVWSYGIVMFEILTWASSPYPDIPAKEVIEKVSK-GYRMPNPEKFITG---VCCPDEIYKIMIWCWDANPEKRPTFLVLQEKM 479
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P12931|SRC_HUMAN (Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens OX=9606 GN=SRC PE=1 SV=3) HSP 1 Score: 328.561 bits (841), Expect = 1.059e-104 Identity = 191/460 (41.52%), Postives = 266/460 (57.83%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + T +G IP NYV D + Y+ +TR ESERLL N GT+L+R + K LSV + N+ H+ I+ D +YI ++FN++ L+ +Y K + LT P + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK + G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLAHSLSTGQTGYIPSNYV-APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPP---------ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQ 531
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|Q1JPZ3|SRC_DANRE (Proto-oncogene tyrosine-protein kinase Src OS=Danio rerio OX=7955 GN=src PE=1 SV=2) HSP 1 Score: 327.791 bits (839), Expect = 1.944e-104 Identity = 194/462 (41.99%), Postives = 276/462 (59.74%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQF---QEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ LSF + L + G +W+ A + T SG IP NYV D + Y+ +TR +SERLL + N GT+L+R S+ +K A + VL NV N+ H+ I+ D +YI ++F+ + L++ Y++ + LT P + PP Q E+ R++ LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK +G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L+ LM++CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 89 ALYDYESRTASDLSFRKGERLQIVNNTEG-DWWLARSLTTGESGYIPSNYV-APSDSIQAEEWYFGKITRRDSERLLLNLENRRGTFLVRE-SETTKGAYCLSVLDYDNVKGLNVKHYKIRKLDSGGFYITSRTQFSTLQQLVNHYRQHADGLCHSLTDVCPVLK-PPTQGLARDAWEIPRDSLRLDVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMGQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCP---------AECPDSLHELMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQ 529
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|Q9WUD9|SRC_RAT (Proto-oncogene tyrosine-protein kinase Src OS=Rattus norvegicus OX=10116 GN=Src PE=1 SV=4) HSP 1 Score: 326.635 bits (836), Expect = 4.598e-104 Identity = 191/460 (41.52%), Postives = 266/460 (57.83%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + T +G IP NYV D + Y+ +TR ESERLL N GT+L+R + K LSV + N+ H+ I+ D +YI ++FN++ L+ +Y K + LT P + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK + G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTETDLSFKKGERLQIVNNTEG-DWWLAHSLSTGQTGYIPSNYV-APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPP---------ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQ 531
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P13116|SRC2_XENLA (Tyrosine-protein kinase Src-2 OS=Xenopus laevis OX=8355 GN=src-b PE=2 SV=3) HSP 1 Score: 325.865 bits (834), Expect = 1.075e-103 Identity = 188/460 (40.87%), Postives = 267/460 (58.04%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTV--PLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ LSF + L + G +W+ A + + +G IP NYV D + Y +TR E+ERLL + N GT+L+R + K LSV + N+ H+ I+ D +YI ++F+++ L+ +Y K + LT P + Q + E+ R++ LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK ++GR +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM CW E RPTF +LQ L ++ + EPQY+
Sbjct: 87 ALYDYESRTETDLSFRKGERLQIVNNTEG-DWWLARSLSSGQTGYIPSNYV-APSDSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDASRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTAVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPPD---------CPESLHDLMFQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQ 527
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: G4LWG5 (Tyrosine-protein kinase OS=Schistosoma mansoni OX=6183 GN=Smp_006920 PE=3 SV=1) HSP 1 Score: 396.741 bits (1018), Expect = 1.662e-129 Identity = 211/459 (45.97%), Postives = 293/459 (63.83%), Query Frame = 3
Query: 204 LKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGS-GNVWNIHHFIIQ--HNDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
++ALYSYQ +N + LSF DI++ + W+ A + T +SG IP NYV + DG P++L+ +YN+ R E++R L ++ N GTYLIRP S+ ALSVR S N+W + H+ I+ N+ ++I I + F NI DL+++Y P L++P PR PP+QF++ E++R++ +I+ LG+G FGEV+ AKW GS VA+K ++ D +F+ EA++MH HP+IV+LLGVCT+PE+QP+YIITE M G L L+++ G LIDI+AQI+ GM+YLE VHRDLRAANILVD ++ VKV+DFGLA+++ D S+ +KFP++WTAPE A+ FS KSDVWSFGIL+YEIVTYG PY M+T++ + E+ K YRL P+ C LYNLM CW A+ ENRPTF L NW E QY
Sbjct: 33 VRALYSYQGHNQDDLSFQKGDIMFVISGM-SDAWWFARHSDTGISGYIPSNYV-CLNDGLPTSLDAWYNIGRREADRKLLLVGNPKGTYLIRPSSETQNYALSVRHYDSEKNMWVVKHYRIRILDNNGGFFISIRTTFPNIQDLVNYYTVHPDGLCCRLSIPCPRAYRPPVQFRDFEINRDSITRIRKLGQGTFGEVYLAKWN--GSVEVAVK-MRLDPTDRSRFIEEARLMHAFHHPRIVQLLGVCTEPEDQPVYIITELMRKGALYDFLRTEEGHKLTLDDLIDIMAQIASGMSYLEEMNSVHRDLRAANILVDQDYSVKVSDFGLAKIISDD--SHADPNTKFPIKWTAPEAALQHIFSIKSDVWSFGILMYEIVTYGGTPYPGMTTRQTVAEVEK-GYRLPCPHTPEHP-----CPDDLYNLMRKCWDARPENRPTFRSLYDVFENWSTHTEAQY 478
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A430QHK8 (Tyrosine-protein kinase OS=Schistosoma bovis OX=6184 GN=DC041_0007532 PE=3 SV=1) HSP 1 Score: 395.971 bits (1016), Expect = 3.395e-129 Identity = 211/459 (45.97%), Postives = 293/459 (63.83%), Query Frame = 3
Query: 204 LKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGS-GNVWNIHHFIIQ--HNDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
++ALYSYQ +N + LSF DI++ + W+ A + T +SG IP NYV + DG P++L+ +Y++ R E++R L ++ N GTYLIRP S+ ALSVR S N+W + H+ I+ N+ ++I I + F NI DLI++Y P L++P PR PP+QF++ E++R++ +I+ LG+G FGEV+ AKW GS VA+K ++ D +F+ EA++MH HP+IV+LLGVCT+PE+QP+YIITE M G L L+++ G LIDI+AQI+ GM+YLE VHRDLRAANILVD ++ VKV+DFGLA+++ D S+ +KFP++WTAPE A+ FS KSDVWSFGIL+YEIVTYG PY M+T++ + E+ K YRL P+ C LYNLM CW A+ ENRPTF L NW E QY
Sbjct: 33 VRALYSYQGHNQDDLSFQKGDIMFVISGM-SDAWWFARHSDTGMSGYIPSNYV-CLNDGLPTSLDAWYDIGRREADRKLLLVGNPKGTYLIRPSSETQNYALSVRHYDSEKNMWVVKHYRIRILDNNGGFFISIRTTFPNIQDLINYYTVHPDGLCCRLSIPCPRAYRPPVQFRDFEINRDSITRIRKLGQGTFGEVYLAKWN--GSVEVAVK-MRLDPTDRSRFIEEARLMHAFHHPRIVQLLGVCTEPEDQPVYIITELMRKGALYDFLRTEEGHKLTLDDLIDIMAQIASGMSYLEEMNSVHRDLRAANILVDQDYSVKVSDFGLAKIISDD--SHADPNTKFPIKWTAPEAALQHIFSIKSDVWSFGILMYEIVTYGGTPYPGMTTRQTVAEVEK-GYRLPCPHTPEHP-----CPDDLYNLMRKCWDARPENRPTFRSLYDVFENWSTHTEAQY 478
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A4E0RBF3 (Tyrosine-protein kinase OS=Fasciola hepatica OX=6192 GN=D915_005801 PE=3 SV=1) HSP 1 Score: 397.512 bits (1020), Expect = 6.680e-129 Identity = 207/459 (45.10%), Postives = 296/459 (64.49%), Query Frame = 3
Query: 204 LKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSG-NVWNIHHFIIQHNDKQ--WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
++ALY+Y + + L+F D ++ D+ W+ A ++RT SG +P NYV V DG P++L+ +Y++ R E++R L ++ N GTYLIRP S+ ALSVR N+W + H+ I+ D +YI F NI DLI++Y + P LT+P PR +PP+QF+ EV+R + ++ LG G FGEVW AKW GS VA+K ++ + +F+ EA++MH HP+IV+LLGVCTQPE+QP+YIITE M NG L+ L+ + GR + LID++AQI+ GM+YLE VHRDLRAANILVD++ VKV+DFGLA+++ D ++ +++KFP++WTAPE A++ FS KSDVWSFG+L+YEIVTYG PY M+ ++ + E+ K YR+ +P+ S+ C LYNLM+ CW A+ ENRPTF L L +W E QY
Sbjct: 100 VRALYTYDGQHPDDLAFQKGDTMFVLSDL-SVEWWFAKHQRTGESGYVPSNYVL-VDDGLPTSLDAWYDIGRREADRKLLLVGNPKGTYLIRPSSEAQNFALSVRHYDQDKNMWVVKHYRIRMLDDNAGYYISNRINFQNIQDLIEYYSRNPEGLCCRLTIPCPRKYHPPVQFRAFEVNRESITTVRSLGHGSFGEVWLAKWN--GSVEVAVK-MRLENTDRARFIEEARLMHTFHHPRIVQLLGVCTQPEDQPVYIITELMRNGALVDFLRREEGRRLELNDLIDMMAQIASGMSYLEEMNSVHRDLRAANILVDSDNSVKVSDFGLAKIISDDTQA--DHQTKFPIKWTAPEAALHHIFSIKSDVWSFGVLMYEIVTYGGTPYPGMAPRQTVAEVEK-GYRMPSPS-----SSGHRCPDDLYNLMLKCWDARPENRPTFRSLNDVLEHWSSHTETQY 545
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A504Z0U1 (Tyrosine-protein kinase OS=Fasciola gigantica OX=46835 GN=FGIG_06184 PE=3 SV=1) HSP 1 Score: 397.512 bits (1020), Expect = 7.051e-129 Identity = 207/459 (45.10%), Postives = 296/459 (64.49%), Query Frame = 3
Query: 204 LKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLG-SGNVWNIHHFIIQHNDKQ--WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
++ALY+Y + + L+F D ++ D+ W+ A ++RT SG +P NYV V DG P++L+ +Y++ R E++R L ++ N GTYLIRP S+ ALSVR N+W + H+ I+ D +YI F NI DLI++Y + P LT+P PR +PP+QF+ EV+R + ++ LG G FGEVW AKW GS VA+K ++ + +F+ EA++MH HP+IV+LLGVCTQPE+QP+YIITE M NG L+ L+ + GR + LID++AQI+ GM+YLE VHRDLRAANILVD++ VKV+DFGLA+++ D ++ +++KFP++WTAPE A++ FS KSDVWSFG+L+YEIVTYG PY M+ ++ + E+ K YR+ +P+ S+ C LYNLM+ CW A+ ENRPTF L L +W E QY
Sbjct: 100 VRALYTYDGQHPDDLAFQKGDTMFVLSDL-SVEWWFAKHQRTGESGYVPSNYVL-VDDGLPTSLDAWYDIGRREADRKLLLVGNPKGTYLIRPSSEAQNFALSVRHYDQEKNMWVVKHYRIRMLDDNAGYYISNRINFQNIQDLIEYYSRNPEGLCCRLTIPCPRKYHPPVQFRAFEVNRESITTVRSLGHGSFGEVWLAKWN--GSVEVAVK-MRLENTDRARFIEEARLMHTFHHPRIVQLLGVCTQPEDQPVYIITELMRNGALVDFLRREEGRRLELNDLIDMMAQIASGMSYLEEMNSVHRDLRAANILVDSDNSVKVSDFGLAKIISDDTQA--DHQTKFPIKWTAPEAALHHIFSIKSDVWSFGVLMYEIVTYGGTPYPGMAPRQTVAEVEK-GYRMPSPS-----SSGHRCPDDLYNLMLKCWDARPENRPTFRSLNDVLEHWSSHTETQY 545
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A3Q0KBZ0 (Tyrosine-protein kinase OS=Schistosoma mansoni OX=6183 PE=3 SV=1) HSP 1 Score: 397.127 bits (1019), Expect = 1.913e-128 Identity = 211/459 (45.97%), Postives = 293/459 (63.83%), Query Frame = 3
Query: 204 LKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGS-GNVWNIHHFIIQ--HNDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
++ALYSYQ +N + LSF DI++ + W+ A + T +SG IP NYV + DG P++L+ +YN+ R E++R L ++ N GTYLIRP S+ ALSVR S N+W + H+ I+ N+ ++I I + F NI DL+++Y P L++P PR PP+QF++ E++R++ +I+ LG+G FGEV+ AKW GS VA+K ++ D +F+ EA++MH HP+IV+LLGVCT+PE+QP+YIITE M G L L+++ G LIDI+AQI+ GM+YLE VHRDLRAANILVD ++ VKV+DFGLA+++ D S+ +KFP++WTAPE A+ FS KSDVWSFGIL+YEIVTYG PY M+T++ + E+ K YRL P+ C LYNLM CW A+ ENRPTF L NW E QY
Sbjct: 117 VRALYSYQGHNQDDLSFQKGDIMFVISGM-SDAWWFARHSDTGISGYIPSNYV-CLNDGLPTSLDAWYNIGRREADRKLLLVGNPKGTYLIRPSSETQNYALSVRHYDSEKNMWVVKHYRIRILDNNGGFFISIRTTFPNIQDLVNYYTVHPDGLCCRLSIPCPRAYRPPVQFRDFEINRDSITRIRKLGQGTFGEVYLAKWN--GSVEVAVK-MRLDPTDRSRFIEEARLMHAFHHPRIVQLLGVCTEPEDQPVYIITELMRKGALYDFLRTEEGHKLTLDDLIDIMAQIASGMSYLEEMNSVHRDLRAANILVDQDYSVKVSDFGLAKIISDD--SHADPNTKFPIKWTAPEAALQHIFSIKSDVWSFGILMYEIVTYGGTPYPGMTTRQTVAEVEK-GYRLPCPHTPEHP-----CPDDLYNLMRKCWDARPENRPTFRSLYDVFENWSTHTEAQY 562
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: src (proto-oncogene tyrosine-protein kinase Src [Source:NCBI gene;Acc:103038924]) HSP 1 Score: 329.717 bits (844), Expect = 5.866e-106 Identity = 195/469 (41.58%), Postives = 278/469 (59.28%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVR-----EVVDGSPSNLE---YYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLT--VPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ LSF + L + G +W+ A + T SG IP NYV + D LE Y+ +TR +SERLL + N GT+L+R S+ +K A + VL NV N+ H+ I+ D +YI ++F+N+ L+ Y+K + LT P+ + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK +G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFG+L+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM++CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTASDLSFRKGERLQIVNNTEG-DWWLARSLTTGESGYIPSNYVAPSDSIQAEDHLRLTLEKRWYFGKITRRDSERLLLSLDNRRGTFLVRE-SETTKGAYCLSVLDFDNVKGLNVKHYKIRKLDSGGFYITSRTQFSNLQQLVSHYRKHADGLCHFLTDVCPVLKPQTQGLARDAWEIPRESLRLDLKLGQGCFGEVWMGTWN--GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMGQGSLLDFLKGDMGKILRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGVLLTELATKGRVPYPGMVNREVLDQV-ERGYRMPCP---------AECPDSLHDLMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQ 540
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: src (proto-oncogene tyrosine-protein kinase Src [Source:NCBI gene;Acc:103038924]) HSP 1 Score: 327.405 bits (838), Expect = 3.222e-105 Identity = 193/466 (41.42%), Postives = 275/466 (59.01%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKN-----WYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLT--VPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ LSF + L + N W+ A + T SG IP NYV D + Y+ +TR +SERLL + N GT+L+R S+ +K A + VL NV N+ H+ I+ D +YI ++F+N+ L+ Y+K + LT P+ + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK +G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFG+L+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM++CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTASDLSFRKGERLQIVNNTRKLNCREGDWWLARSLTTGESGYIPSNYV-APSDSIQAEEWYFGKITRRDSERLLLSLDNRRGTFLVRE-SETTKGAYCLSVLDFDNVKGLNVKHYKIRKLDSGGFYITSRTQFSNLQQLVSHYRKHADGLCHFLTDVCPVLKPQTQGLARDAWEIPRESLRLDLKLGQGCFGEVWMGTWN--GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMGQGSLLDFLKGDMGKILRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGVLLTELATKGRVPYPGMVNREVLDQV-ERGYRMPCP---------AECPDSLHDLMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQ 537
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: src (proto-oncogene tyrosine-protein kinase Src [Source:NCBI gene;Acc:103038924]) HSP 1 Score: 326.25 bits (835), Expect = 1.536e-104 Identity = 195/474 (41.14%), Postives = 277/474 (58.44%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKN-----WYNAINKRTQLSGMIPYNYVR-----EVVDGSPSNLE---YYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLT--VPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ LSF + L + N W+ A + T SG IP NYV + D LE Y+ +TR +SERLL + N GT+L+R S+ +K A + VL NV N+ H+ I+ D +YI ++F+N+ L+ Y+K + LT P+ + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK +G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFG+L+ E+ T G +PY M +EVLD++ +R YR+ P C L++LM++CW + E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTASDLSFRKGERLQIVNNTRKLNCREGDWWLARSLTTGESGYIPSNYVAPSDSIQAEDHLRLTLEKRWYFGKITRRDSERLLLSLDNRRGTFLVRE-SETTKGAYCLSVLDFDNVKGLNVKHYKIRKLDSGGFYITSRTQFSNLQQLVSHYRKHADGLCHFLTDVCPVLKPQTQGLARDAWEIPRESLRLDLKLGQGCFGEVWMGTWN--GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMGQGSLLDFLKGDMGKILRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGVLLTELATKGRVPYPGMVNREVLDQV-ERGYRMPCP---------AECPDSLHDLMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQ 546
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: SRC (proto-oncogene tyrosine-protein kinase Src-like [Source:NCBI gene;Acc:103042998]) HSP 1 Score: 322.013 bits (824), Expect = 5.260e-103 Identity = 192/473 (40.59%), Postives = 278/473 (58.77%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLT--VPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEEQ*LLYIYTNFS 1607
ALY Y++ L+F + L + G +W+ A + T SG IP NYV D + ++ +TR +SERLL + N GT+L+R S+ +K A + VL N+ NI H+ I+ D +YI ++F ++ L+ Y+ + LT P+ + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ +R YR+ P C + ++ LM+SCW + E RPTF +LQ L ++ S EPQY+ + L++Y +S
Sbjct: 91 ALYDYESRTTADLTFKKGERLQILNNTEG-DWWLARSLTTGESGYIPSNYV-APSDSIQAEEWFFGKITRRDSERLLLNIQNRRGTFLVRE-SETTKGAYCLSVLDYDNMKGLNIKHYKIRKLDSGGFYITSRTQFTSLQQLVLHYRTHADGLCHVLTDICPMLKPQTQGLARDAWEIPRESLRLDVKLGQGCFGEVWMGTW--NGTTRVAIKTLKRGTMSPEAFLEEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSQGSLLDFLKGDKGKFLRLPQLVDMASQIAAGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELATKGRVPYPGMVNREVLDQV-ERGYRMPCP---------AECPSSMHELMLSCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQPE-NLFLYKIYS 542
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: lyn (tyrosine-protein kinase Lyn-like [Source:NCBI gene;Acc:103026730]) HSP 1 Score: 320.472 bits (820), Expect = 6.950e-103 Identity = 189/465 (40.65%), Postives = 268/465 (57.63%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPL--PRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEEQ 1577
++ ALY Y+ + + L F + L E+ W+ A + T+ G IP NYV + D + ++ +TR ++ER L +N G YLIR + K +LS+R G + H+ I+ D +YI F +I +I Y K L P P+ Q P E+S+ + +K LG G FGEVW A + + VA+K ++ MS E FL EA +M L+H ++V L V T+ E PIYIITEFM NG LL LKS G KLID AQI+EGMAY+E K Y+HRDLRAAN+LV + + K+ADFGLARV++ D+ YTA E +KFP++WTAPEA+ YG+F+ KSD+WSFGIL+YEI+TYG +PY MS EV+ + +R YR+ P C T LY++M +CW + ++RPTF ++Q L ++ + E QY++Q
Sbjct: 70 IVIALYPYEAIHTDDLGFKKGEKLRVLEE--HGEWWKAKSLSTRKEGFIPSNYVAQA-DTMETEEWFFKEITRKDAERQLLAPANKPGAYLIRESETSKGSYSLSIRDAGPQGSDVVKHYKIRSLDNGGYYISPKITFPDIIKMIHHYHKQADGLCRKLERPCEKPKAQKP-WDKDAWEISKESIKMVKKLGAGQFGEVWMAYYN--NTTKVAVKTLKPGTMSVEAFLEEANLMKTLQHERLVRLYAVVTKIE--PIYIITEFMANGSLLDFLKSDAGSKLQLPKLIDFSAQIAEGMAYIEKKNYIHRDLRAANVLVSESLLCKIADFGLARVIEDDQ--YTAREGAKFPIKWTAPEAINYGSFTIKSDMWSFGILLYEIITYGKIPYPGMSNGEVMTSV-QRGYRMPRPES---------CPTELYDIMNTCWKNKPDDRPTFDYIQSVLDDFYTATEGQYQQQ 514
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: clul1 (clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GENE-031118-57]) HSP 1 Score: 311.227 bits (796), Expect = 1.637e-100 Identity = 183/467 (39.19%), Postives = 261/467 (55.89%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFD-------VNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTP--IIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y + LSF +N+ + +W+ A + T G IP NYV D + Y+ V+R ++ER L N GT+LIR + K +LS+R N+ H+ I+ D +YI ++F+ + L+ Y + + L P + Q + E+ R++ LG+GCFGEVW W G+ VAIK ++ MS E FL EA++M KLRH K+V+L V ++ +PIYI+TEFM G LL LK GR +L+D+ AQI+ GMAY+E Y+HRDLRAANILV N + K+ADFGLAR+++ +E YTA + +KFP++WTAPE A++G F+ KSDVWSFGIL+ E+VT G +PY M +EVL+++ +R YR+ P C L+ LMM CW E RPTF +LQ L ++ + EPQY+
Sbjct: 20 ALYDYDARTQDDLSFRKGEKFQIINNTIEVAVVYREGDWWEARSLSTGNKGYIPSNYVAPA-DSVQAEEWYFGKVSRKDAERQLLCPGNPRGTFLIRESETTKGAYSLSIRDWDEVKGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVQHYSEHADGLCYKLTLVCPNEKPQTQGLARDAWEMPRDSLKLELKLGQGCFGEVWAGTWN--GTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSE---EPIYIVTEFMSKGSLLDFLKEGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAAMFGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQV-ERGYRMPCPPS---------CPESLHELMMQCWKKDPEERPTFEYLQAFLEDYFTATEPQYQ 468
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: hck (HCK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-090313-72]) HSP 1 Score: 302.368 bits (773), Expect = 2.504e-97 Identity = 191/464 (41.16%), Postives = 261/464 (56.25%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYN-VTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQWYIIIDS-KFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEM---EVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEEQ 1577
ALY ++ N + + F D + ++ W+ A G IP NYV + S E++++ V+R E ERLL N G YL+R S+K +LSVR N + H+ I+ D Y I F ++ LI Y T C + P P Q E E+ R++ K LG G FGEVW + R VAIK ++ MS E FL EA +M L+HP++V L V TQ +PIYI+TEFM NG LL LKS G + K+ID+ AQI+EGMA++E K Y+HRDLRAANILV+ K+ADFGLAR+++ +E YTA E +KFP++WTAPEA+ YG+FS KSDVWSFGIL+ EI+T+G +PY MS +V+ ++ +R YR+ P A LY +MM CW + E RPTF +LQ L ++ S E QY++Q
Sbjct: 5 ALYDFEQLNPDDMGFKKGDKMRIIQE--RGEWWMAELMDGSHKGYIPSNYVAKA--NSLETEEWFFSGVSRKEGERLLLAPGNSIGAYLLRDSESNKGSYSLSVRDYDITNGDVVRHYKIRTLDNGGYFISARLTFPDLFALIQHY--TAHSDGLCQKLLRPCVSKKPQQLWEKDAWEIPRDSLKLSKRLGAGQFGEVWMGIYNNRTK--VAIKTMKPGSMSPEAFLDEANLMKTLQHPRLVRLYAVVTQ---EPIYIVTEFMENGSLLDYLKSTEGSTLPMPKMIDMAAQIAEGMAFIERKNYIHRDLRAANILVNEQLASKIADFGLARIIEDNE--YTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEIITFGRIPYPGMSNSDVIRQL-ERGYRMPCPEQA---------PKQLYGVMMDCWKERPEERPTFEYLQGVLEDFFTSTEGQYQQQ 445
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: hck (HCK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-090313-72]) HSP 1 Score: 298.13 bits (762), Expect = 5.527e-95 Identity = 180/468 (38.46%), Postives = 274/468 (58.55%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYY-NVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVR--VLGSGNVWNIHHFIIQHNDKQWYIIIDS-KFNNISDLIDFYKKTPIIKNNCLTVPLPR-----NQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEEQ 1577
ALY Y +A+ L F D L E+ G +W+ A + T+ G IP N+V +V S E+++ ++R ++ER L + N G+YLIR ++K +LSVR ++ G+ + H+ I+ DK Y I F+ + +L+ +Y +K + L L + P + E+ R + K LG G FG+VW + ++ VA+K+++ M+ + FL EA +M L+H K+V L V T ++PI+I+TE+M G LL LK+ G K+ID+ AQ++EGMA++E K Y+HRDLRAANILV+ N + K+ADFGLAR+++ +E YTA E +KFP++WTAPEA+ YG+FS KSDVWSFGIL+ E+VT+G +PY M+ EV+ + +R YR+ P+ C LY++M CW + E RPTF +LQ L ++ + E QY+ Q
Sbjct: 70 ALYDYDPIHADDLCFRRGDQLVIVEE--GNDWWKARSVATKKEGYIPSNFVAKV--NSIEKEEWFFKGLSRKDAERQLLLCGNKIGSYLIRDSETNKGSYSLSVRDHIVEVGD--TVKHYKIRTLDKGGYFITSRITFHTLQELVVYYH----LKADGLCQKLGKPCIAIQPQKPWEKDAWEIPRESIKLEKKLGAGQFGDVWMGVYNKKTK--VAVKMMKPGSMAPQAFLEEANLMKTLQHDKLVRLHAVVT---DEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNE--YTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSL-ERGYRMPKPDN---------CPCELYSIMQECWRQKPEERPTFEYLQSLLEDFYTATELQYQPQ 510
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: frk (fyn-related Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-110411-7]) HSP 1 Score: 291.582 bits (745), Expect = 4.960e-93 Identity = 177/467 (37.90%), Postives = 256/467 (54.82%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWY------NAINKRTQLSGMIPYNYVREV--VDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPC-SDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQWYIIIDSK--FNNISDLIDFYKKTP-----IIKNNCLTVPLPRNQNPPIQ-FQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQ---QDEESYTANESKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWD 1547
ALY Y LSF ++L T+ WY + N+R G IP NYV E +D P ++ ++ R ++E+ L N +G +LIR S K+ +LSVR GS + H+ I+ D+ I + F N+ +L+ +YK ++ C+ + P + E+ R + K LG G FGEVWQ W S +VA+K ++ M E+F+ EA++M +LRH +++L VC+Q E PIYIITE M +G LL L+ +G+ +L+D+ QI+ GMAYLES+ Y+HRDL A NILV + KVADFGLAR+++ +DE A +K P++WTAPEAV + FS KSDVWSFGIL+YE++TYG MPY M EVL ++ R YR+ P+ C Y++M+ CW+ + E RPTF LQ+ L +D
Sbjct: 3 ALYDYDGRTNEDLSFKEGELLEVTDKTNSDWWYAQKKTASTSNERYNTRGYIPANYVAEYQSLDAEPW---FFGDIKRADAEKYLLADVNTTGAFLIRQSESRKTDYSLSVRD-GS----TVKHYRIRQLDENGGFFISRRVTFQNLIELVQYYKSNSDGLCMALQKPCVVIEAPTTIGLSYNTVDKWEIPRASIQLQKRLGAGMFGEVWQGLWN--NSTLVAVKTLKPGAMKKEEFIGEAQIMKQLRHANLIQLYAVCSQEE--PIYIITELMRHGSLLDYLRGPLGKQLKAPELVDMARQIAAGMAYLESQNYIHRDLAARNILVGEGKVCKVADFGLARIIKVRYEDEYEGKAG-AKVPIKWTAPEAVNFHRFSVKSDVWSFGILLYELITYGRMPYPEMGNMEVLKQL-DRGYRMPQPDN---------CPPLFYSIMLECWNKKEEERPTFETLQWRLDYFD 446
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006670.1 (pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene:ENSPMAG00000006016.1 transcript:ENSPMAT00000006670.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 278.485 bits (711), Expect = 4.986e-89 Identity = 157/385 (40.78%), Postives = 231/385 (60.00%), Query Frame = 3
Query: 429 ERLLQVM--SNISGTYLIRPCSDKSKT-ALSVRVLGSGNVWNIHHFIIQHNDK-QWYIIIDSKFNNISDLIDFYKKTP-----IIKNNCLTVPLPRNQNPPIQFQEM-EVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQ-QDEESYTAN-ESKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNW 1544
++LLQ+M N+ G++L+R +LSVR G+ + H+ I+ +K ++I ++F + DL+ Y + + CL +P+ + + E+ R++ +K LG G FGEVWQ W + + VAIK ++ M + FL EA++M +LRHPK+++L VCTQ E PIYIITE M NG L + L++ GRS D +L+D+ AQ++ GMAYLE++ Y+HRDL A NILV + KVADFGLARV++ +E+ Y A SKFP++WTAPEA Y FS KSDVWSFG+L++EI+TYG +PY + EVL + R YR+ P G C Y+LM+ CW+ + RPTF LQ++L ++
Sbjct: 5 QQLLQLMKSGNVHGSFLVRQSETSGHGYSLSVR---DGDT--VKHYKIRVLEKGSFFITRRNQFATLRDLVQSYSRDANGLCVTLNQPCLKKEMPQTEGLSSDMADKWEIPRSSVQLVKRLGAGQFGEVWQGLWNK--TTPVAIKTLKQGTMDRDDFLREAQLMKRLRHPKLIQLYAVCTQEE--PIYIITELMSNGSLANYLQTPEGRSLDLVELVDMAAQVAAGMAYLEAQNYIHRDLAARNILVAEHNACKVADFGLARVIKMSNEDEYEARVGSKFPIKWTAPEAANYNRFSIKSDVWSFGVLLHEIITYGKLPYPGQTNAEVLAAV-DRGYRMPCPPG---------CPQAFYDLMLECWNVDDQARPTFETLQWQLEDF 370
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: CDC5 (Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]) HSP 1 Score: 97.8265 bits (242), Expect = 7.665e-22 Identity = 68/245 (27.76%), Postives = 118/245 (48.16%), Query Frame = 3
Query: 693 QNPP--IQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQ----FLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVL-QQDEESYTANESKFPVRWTAPEAVYGTFSTKS---DVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNY 1397
+ PP I+ + + R +F LG+G F +Q K + + A K + + +E+ L+E ++ + HP IV+ + N +YI+ E NG L+ LLK + + ++ QI + Y+ S+ +HRDL+ NI D+N+ +K+ DFGLA VL + E YT + + APE + G S S D+WS G+++Y ++ G P+ + + I R++
Sbjct: 69 KTPPSLIKTRGKDYHRGHF-----LGEGGFARCFQIK--DDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSN--VYILLEICPNGSLMELLKRR--KVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTP---NYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLI-GKPPFQARDVNTIYERIKCRDF 298
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: SPS1 (Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]) HSP 1 Score: 92.0485 bits (227), Expect = 2.769e-20 Identity = 67/240 (27.92%), Postives = 118/240 (49.17%), Query Frame = 3
Query: 687 RNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSN--EQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAV---YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKR 1391
R++ PP + ++ +G+G FG+V++A +VAIKV+ + E E + +L+ P I + T E+ ++I+ E+ G LLK +K+ II +++ G+ YL + +HRD++AANIL++ MVK+ DFG++ ++ + T + + W APE V ++ K+D+WS GI YE++ G P S +V+ + KR
Sbjct: 9 RSRTPPSKLYSIQ---------SCIGRGNFGDVYKA-VDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNY--IATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPY---WMAPEVVCCEVDGYNEKADIWSLGITTYELLK-GLPPLSKYDPMKVMTNLPKR 232
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]) HSP 1 Score: 92.4337 bits (228), Expect = 5.554e-20 Identity = 77/271 (28.41%), Postives = 135/271 (49.82%), Query Frame = 3
Query: 741 FIKIKVLGKGCFGEVW---QAKWGERGSHVVAIKVIQSDMMSN---------EQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAV--YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPT 1511
++K +++GKG FG V+ GE ++A+K ++ S+ E +E + L H IV+ LG + +N + E++ G + SL++ GR FD + + Q+ +G+AYL SK +HRD++A N+L+D + + K++DFG++R +D S + + V W APE V +S K D+WS G ++ E+ G P+S + EV+ + K S P + + + + N + +C+ E RPT
Sbjct: 1175 WMKGEMIGKGSFGAVYLCLNVTTGE----MMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGF--ENKNNIYSLFLEYVAGGSVGSLIR-MYGR-FDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRK-SKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFA-GKRPWSNL---EVVAAMFKIGKSKSAP--PIPEDTLPLISQIGRNFLDACFEINPEKRPT 1430
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: MKK1 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]) HSP 1 Score: 90.5077 bits (223), Expect = 8.720e-20 Identity = 66/208 (31.73%), Postives = 104/208 (50.00%), Query Frame = 3
Query: 750 IKVLGKGCFGEVWQAKWGERGSHVVAIKVIQS---DMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRS--FDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLA-RVLQQDEESYTANESKFPVRWTAPEAVYG-TFSTKSDVWSFGILIYEIVTYGAMPYST 1352
+ +LG+G G V + K + GS + A+KVI + D +Q E + + IV G+ T EN IYI E+M L ++ K+ + R K L I + G++YL K +HRD++ NIL++ N VK+ DFG++ + ++T + F + APE + G +S SDVWS G+ I E+ G P S+
Sbjct: 224 LGILGEGAGGSVSKCKL-KNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTG--TSF---YMAPERIQGQPYSVTSDVWSLGLTILEVAN-GKFPCSS 424
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: RAD53 (DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]) HSP 1 Score: 90.1225 bits (222), Expect = 2.301e-19 Identity = 71/233 (30.47%), Postives = 117/233 (50.21%), Query Frame = 3
Query: 753 KVLGKGCFGEVWQAKWGERGSHVVAIKVI-QSDMMSNEQFLT-EAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILV--DANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAVYGT--------------FSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNY 1397
+V+G+G F V +A G A+K+I + ++ N +T E +V+ KL HP+IV L G E+ Y++ EF+ GDL+ + + D + +I QI + Y+ S HRDL+ NIL+ D +VK+ DFGLA+V Q S+ + + APE + G +S+ D+WS G L+Y I+T G +P+S + ++ +I + +Y
Sbjct: 202 EVVGQGAFATVKKAIERTTGK-TFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTES--YYMVMEFVSGGDLMDFVAAHGAVGEDAGR--EISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKV--QGNGSFMKTFCG-TLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILT-GHLPFSGSTQDQLYKQIGRGSY 425
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO47195 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN18]) HSP 1 Score: 221.476 bits (563), Expect = 4.900e-68 Identity = 117/277 (42.24%), Postives = 172/277 (62.09%), Query Frame = 3
Query: 717 EMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSN 1541
E E+ R LG G +GEV++ W ++ + VA+K ++ + M E+FL EA VM ++H +V+LLGVCT+ P YIITEFM NG+LL L+S G+ D L+ + Q+ M+YLES ++HRDL A N LV N +VKVADFGL+R++ +D YTA++ +KFP++WTAPEA+ + TFS KSDVW+FGIL++E+ TYG PY + +V D++ YR+ P G C +Y+LM +CW +RP+F + +L+
Sbjct: 6 EWEIERTEIAMKHKLGGGQYGEVYEGTW-KKYNKTVAVKTLREETMEVEEFLKEASVMKGIKHQNLVQLLGVCTR--EPPFYIITEFMMNGNLLDYLRSPKGKDLDAVTLMYMATQVGSAMSYLESMNFIHRDLAARNCLVGDNNLVKVADFGLSRLVSED--IYTAHQGAKFPIKWTAPEALAHNTFSIKSDVWAFGILLWELATYGMSPYPGIDLSQVYDKLDG-GYRMPCPEG---------CPPEVYSLMQTCWCWDPNSRPSFKEIHEKLNT 267
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO49804 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFY7]) HSP 1 Score: 177.563 bits (449), Expect = 2.968e-52 Identity = 98/230 (42.61%), Postives = 139/230 (60.43%), Query Frame = 3
Query: 807 RGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLL-KSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWH 1487
RG+ VA+K+++ MS E F+ EAKVM + +H +V+L G+C++ +PIYII E M G LL L KSQ ++ +++ Q++ M YLES ++HRDL A N L+ N VKVADFGLAR + DE YTA+E +KFP++W APE + Y FS+KSDVW+FGIL +E+ T G PY + +V+ ++ YRL P + C Y+ M CWH
Sbjct: 3 RGTIPVAVKMMKDGAMSEEDFIEEAKVMKQFQHGNLVQLYGICSE---KPIYIIQELMKGGCLLHYLRKSQF--KLQSAEMTEMVRQVAAAMKYLESHNFIHRDLAARNCLIGENRTVKVADFGLARYVIDDE--YTASEGTKFPIKWAAPEVILYSKFSSKSDVWAFGILAWEVYTGGKQPYPATNNTDVV-QMVINGYRLEKP---------LRCPDAAYSTMRKCWH 215
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO33736 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRD7]) HSP 1 Score: 182.185 bits (461), Expect = 5.781e-52 Identity = 102/274 (37.23%), Postives = 158/274 (57.66%), Query Frame = 3
Query: 723 EVSRNNFIKIKVLGKGCFGEVWQAKWG--ERGSHVVAIKVIQ--SDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVL----QQDEESYTANESKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFS 1517
E+++++ ++G G F +V++ ++ VA+K+++ S + E F EA +M + HP ++ L GV T+ +P+ IITEF+ NG L + LKS GR + L+ I ++ GMAYL ++HRDL A NILV N KV+DFGL+R L + ++ Y K PVRWTAPEA+ Y FS+ SDVWS+GIL++EI+++G PY T +V+D + + YRL P + C ++NLM+ CW + +RP F+
Sbjct: 21 EINKDDLKLEIIIGGGEFADVYRGVLTNEDKTQEKVAVKILKPGSSHKNREDFCVEASIMGQFDHPNVIALKGVITR--TRPMMIITEFLENGSLDNFLKSNDGRLTTLQ-LVGIGRGVAAGMAYLSEMNFIHRDLAARNILVSDNLAAKVSDFGLSRELDDSPENEQSEYQTQGGKIPVRWTAPEAIRYRKFSSASDVWSYGILLWEIMSFGERPYWTWDNFQVMDRV-EGGYRLPAP---------MKCPKVIHNLMLDCWDKEKTSRPKFA 281
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO31298 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYB5]) HSP 1 Score: 174.866 bits (442), Expect = 1.236e-50 Identity = 104/283 (36.75%), Postives = 162/283 (57.24%), Query Frame = 3
Query: 690 NQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKW----GERGSHVVAIKVIQSDMMSN--EQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANES-KFPVRWTAPEAVY-GTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTF 1514
NQ +Q Q E+ N K LG G FG V + + GER VA+K ++SD ++N + L EA+VM +L HP IV ++G+C P + ++ E G L LK G ++ ++ Q++EGM YLES +VHRDL A N+LV + VK++DFG++R + + Y A + ++P++W APE +Y FS+KSDVWS+GI ++E +YGA PY ++S + +L++I + YRL P + + C +Y LM CW + ++RP+F
Sbjct: 9 NQFKAVQSQTFELKMENLSLGKELGHGNFGSVLKGTYKMPNGERIP--VAVKSLKSDDINNPKSEILHEARVMMELDHPYIVRIIGMCQGPS---MMLVMELAGEGPLNKYLKKNKG--MPLLNILVLMLQVAEGMQYLESLQFVHRDLAARNVLVVNDSFVKISDFGMSRAMGAGSDYYKAGTAGRWPLKWYAPECIYFRKFSSKSDVWSYGITLWEATSYGARPYQSLSGQAILEKI-ESGYRLPAP------AKLPSC---VYQLMKDCWQWEQDDRPSF 274
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO28980 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4Y3]) HSP 1 Score: 174.096 bits (440), Expect = 1.146e-49 Identity = 93/224 (41.52%), Postives = 132/224 (58.93%), Query Frame = 3
Query: 861 EQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVL----QQDEESYTANESKFPVRWTAPEAV-YGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFS 1517
E F EA +M + HP ++ L GV T+ +P+ IITEF+ NG L + LKS GR + L+ I ++ GMAYL ++HRDL A NILV N KV+DFGL+R L + ++ Y K PVRWTAPEA+ Y FS+ SDVWS+GIL++EI+++G PY T +V+D + + YRL P + C ++NLM+ CW + +RP F+
Sbjct: 8 EDFCVEASIMGQFDHPNVIALKGVITR--TRPMMIITEFLENGSLDNFLKSNDGRLTTLQ-LVGIGRGVAAGMAYLSEMNFIHRDLAARNILVSDNLAAKVSDFGLSRELDDSPENEQSEYQTQGGKIPVRWTAPEAIRYRKFSSASDVWSYGILLWEIMSFGERPYWTWDNFQVMDRV-EGGYRLPAP---------MKCPKVIHNLMLDCWDKEKTSRPKFA 218
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:NCBI gene;Acc:101173856]) HSP 1 Score: 331.257 bits (848), Expect = 1.042e-106 Identity = 193/461 (41.87%), Postives = 272/461 (59.00%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLT--VPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ L+F D L + G +W+ A + T SG IP NYV D + Y+ +TR +SERLL + N GT+L+R S+ +K A + VL N N+ H+ I+ D +YI ++F ++ L+ Y+K + LT P+ + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK G+ +L+D+ AQI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFG+L+ E+ T G +PY M +EVLD++ +R YR+ P C + L+ LM+SCW E RPTF +LQ L ++ S EPQY+
Sbjct: 99 ALYDYESRTASDLTFRKGDRLQIVNNTEG-DWWLARSLTTGESGYIPSNYV-APSDSIQAEEWYFGKITRRDSERLLLNLQNRRGTFLVRE-SETTKGAYCLSVLDYDNAKGLNVKHYKIRKLDSGGFYITSRTQFTSLQQLVFHYRKHSDGLCHALTDVCPVAKPQTQGLARDAWEIPRESLRLDVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSQGSLLDFLKGDTGKLLRLPQLVDMAAQIAAGMAYVEKMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGVLLTELATKGRVPYPGMVNREVLDQV-ERGYRMPCP---------AECPSSLHELMLSCWRKDPEERPTFEYLQGFLEDYFTSTEPQYQ 539
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: src (proto-oncogene tyrosine-protein kinase Src [Source:NCBI gene;Acc:101164480]) HSP 1 Score: 327.791 bits (839), Expect = 2.584e-105 Identity = 193/469 (41.15%), Postives = 276/469 (58.85%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVR-----EVVDGSPSNLE---YYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLT--VPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ LSF + L + G +W+ A + T SG IP NYV + D L+ Y+ +TR +SERLL + N GT+L+R S+ +K A + VL N N+ H+ I+ D +YI ++F+ + L++ Y+K + LT P+ + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK +G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ R YR+ P C L+ LM++CW ++E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTASDLSFRKGERLQIVNNTEG-DWWLARSLATGESGYIPSNYVAPSESIQAEDDLKLTLDSRWYFGKITRRDSERLLLSLENRRGTFLVRE-SETTKGAYCLSVLDYDNTKGLNVKHYKIRKLDSGGFYITSRTQFSGLQPLVNHYRKHADGLCHSLTDICPVLKPQTQGLAKDAWEIPRESLRLDVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELATKGRVPYPGMVNREVLDQV-DRGYRMPCPAD---------CPESLHELMLTCWRKEAEERPTFEYLQSFLEDYFTSTEPQYQ 540
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: src (proto-oncogene tyrosine-protein kinase Src [Source:NCBI gene;Acc:101164480]) HSP 1 Score: 325.479 bits (833), Expect = 2.347e-104 Identity = 194/471 (41.19%), Postives = 276/471 (58.60%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKN-----WYNAINKRTQLSGMIPYNYVREVVDGSPSNL----EYYYN-VTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLT--VPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ LSF + L + N W+ A + T SG IP NYV +PS E+Y+ +TR +SERLL + N GT+L+R S+ +K A + VL N N+ H+ I+ D +YI ++F+ + L++ Y+K + LT P+ + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK +G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ R YR+ P C L+ LM++CW ++E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTASDLSFRKGERLQIVNNTRKVNCREGDWWLARSLATGESGYIPSNYV------APSESIQAEEWYFGKITRRDSERLLLSLENRRGTFLVRE-SETTKGAYCLSVLDYDNTKGLNVKHYKIRKLDSGGFYITSRTQFSGLQPLVNHYRKHADGLCHSLTDICPVLKPQTQGLAKDAWEIPRESLRLDVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELATKGRVPYPGMVNREVLDQV-DRGYRMPCPAD---------CPESLHELMLTCWRKEAEERPTFEYLQSFLEDYFTSTEPQYQ 537
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: src (proto-oncogene tyrosine-protein kinase Src [Source:NCBI gene;Acc:101164480]) HSP 1 Score: 323.553 bits (828), Expect = 1.414e-103 Identity = 193/474 (40.72%), Postives = 275/474 (58.02%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKN-----WYNAINKRTQLSGMIPYNYVR-----EVVDGSPSNLE---YYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLT--VPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ LSF + L + N W+ A + T SG IP NYV + D L+ Y+ +TR +SERLL + N GT+L+R S+ +K A + VL N N+ H+ I+ D +YI ++F+ + L++ Y+K + LT P+ + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK +G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ R YR+ P C L+ LM++CW ++E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTASDLSFRKGERLQIVNNTRKVNCREGDWWLARSLATGESGYIPSNYVAPSESIQAEDDLKLTLDSRWYFGKITRRDSERLLLSLENRRGTFLVRE-SETTKGAYCLSVLDYDNTKGLNVKHYKIRKLDSGGFYITSRTQFSGLQPLVNHYRKHADGLCHSLTDICPVLKPQTQGLAKDAWEIPRESLRLDVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELATKGRVPYPGMVNREVLDQV-DRGYRMPCPAD---------CPESLHELMLTCWRKEAEERPTFEYLQSFLEDYFTSTEPQYQ 546
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: src (proto-oncogene tyrosine-protein kinase Src [Source:NCBI gene;Acc:101164480]) HSP 1 Score: 319.316 bits (817), Expect = 3.458e-102 Identity = 192/466 (41.20%), Postives = 274/466 (58.80%), Query Frame = 3
Query: 210 ALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNL----EYYYN-VTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNV--WNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLT--VPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPE-AVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYE 1571
ALY Y++ A+ LSF + L + G +W+ A + T SG IP NYV +PS E+Y+ +TR +SERLL + N GT+L+R S+ +K A + VL N N+ H+ I+ D +YI ++F+ + L ++ + LT P+ + Q + E+ R + LG+GCFGEVW W G+ VAIK ++ MS E FL EA+VM KLRH K+V+L V ++ +PIYI+TE+M G LL LK +G+ +L+D+ +QI+ GMAY+E YVHRDLRAANILV N + KVADFGLAR+++ +E YTA + +KFP++WTAPE A+YG F+ KSDVWSFGIL+ E+ T G +PY M +EVLD++ R YR+ P C L+ LM++CW ++E RPTF +LQ L ++ S EPQY+
Sbjct: 91 ALYDYESRTASDLSFRKGERLQIVNNTEG-DWWLARSLATGESGYIPSNYV------APSESIQAEEWYFGKITRRDSERLLLSLENRRGTFLVRE-SETTKGAYCLSVLDYDNTKGLNVKHYKIRKLDSGGFYITSRTQFSGLQ-LSRYFPAHADGLCHSLTDICPVLKPQTQGLAKDAWEIPRESLRLDVKLGQGCFGEVWMGTW--NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELATKGRVPYPGMVNREVLDQV-DRGYRMPCPAD---------CPESLHELMLTCWRKEAEERPTFEYLQSFLEDYFTSTEPQYQ 530
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000015831.1 (SMESG000015831.1) HSP 1 Score: 1017.3 bits (2629), Expect = 0.000e+0 Identity = 506/506 (100.00%), Postives = 506/506 (100.00%), Query Frame = 3
Query: 60 MGNLAFRKRGKSDKFKSKNQSCLSQSVDDLXXXXXXXXXXXXXXXXXVLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEEQ 1577
MGNLAFRKRGKSDKFKSKNQSCLSQSVDDLTPSSPTTKQTKPNTNYTVLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEEQ
Sbjct: 1 MGNLAFRKRGKSDKFKSKNQSCLSQSVDDLTPSSPTTKQTKPNTNYTVLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGSGNVWNIHHFIIQHNDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANESKFPVRWTAPEAVYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQYEEQ 506
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000045588.1 (SMESG000045588.1) HSP 1 Score: 405.986 bits (1042), Expect = 3.264e-136 Identity = 216/461 (46.85%), Postives = 305/461 (66.16%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGS-GNVWNIHHFIIQ--HNDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPEA-VYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
++AL+SY+ + + L F D++Y + D+ + W+ A++ T+ +G IP NYV + DGSPS+ E +Y++T E+++ L M N GTY+IRPCSD ALSVR + N + + H+ I+ N+ +YI SKF NIS LI +Y+ LT+ P+ PPIQF+++EVSR+ +VLG G FGEV+ KW S VA+K ++ + M +F+ EA++MHKL HP+IV++LGVCTQP QP++IITE M NG LL+ L+S G+ +++D+++QI+EGMAYLES+ +VHRDLRAANILVD + VKVADFGLARV ++ Y A+ +KFP++WTAPEA + FS KSDVWSFG+L+YEIVTYG PY + ++VLDE++K YRL NP G I+C LY + + CW A ENRPTFS LQ +W+++AE QY
Sbjct: 68 TVRALFSYEARHTDDLEFSKGDLMYISSDM-SEAWWLALHATTKKTGYIPSNYV-VLDDGSPSSHEGWYDITHKEADKKLLRMGNPIGTYIIRPCSDSKHYALSVRHFDTTKNYYVVKHYKIRTLDNNLGFYISNRSKFPNISSLIKYYQTNTDGLCCKLTLSCPQRHKPPIQFKDIEVSRDCIRLERVLGNGSFGEVYLGKWN--NSVEVAVKQLKPNSMDRSRFIAEAELMHKLNHPRIVQILGVCTQPPEQPVFIITELMANGALLNYLRSPEGQKLRLNEMLDMMSQIAEGMAYLESRNFVHRDLRAANILVDEDLSVKVADFGLARVT---DDVYNADTGTKFPIKWTAPEAGMQRRFSVKSDVWSFGVLMYEIVTYGRTPYPGIPNRQVLDEVSK-GYRLPNPAGG-----KIVCPDELYAIKLKCWDAYPENRPTFSHLQDIFEHWEINAESQY 515
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000029204.1 (SMESG000029204.1) HSP 1 Score: 405.986 bits (1042), Expect = 3.264e-136 Identity = 216/461 (46.85%), Postives = 305/461 (66.16%), Query Frame = 3
Query: 201 VLKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLGS-GNVWNIHHFIIQ--HNDKQWYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPEA-VYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
++AL+SY+ + + L F D++Y + D+ + W+ A++ T+ +G IP NYV + DGSPS+ E +Y++T E+++ L M N GTY+IRPCSD ALSVR + N + + H+ I+ N+ +YI SKF NIS LI +Y+ LT+ P+ PPIQF+++EVSR+ +VLG G FGEV+ KW S VA+K ++ + M +F+ EA++MHKL HP+IV++LGVCTQP QP++IITE M NG LL+ L+S G+ +++D+++QI+EGMAYLES+ +VHRDLRAANILVD + VKVADFGLARV ++ Y A+ +KFP++WTAPEA + FS KSDVWSFG+L+YEIVTYG PY + ++VLDE++K YRL NP G I+C LY + + CW A ENRPTFS LQ +W+++AE QY
Sbjct: 68 TVRALFSYEARHTDDLEFSKGDLMYISSDM-SEAWWLALHATTKKTGYIPSNYV-VLDDGSPSSHEGWYDITHKEADKKLLRMGNPIGTYIIRPCSDSKHYALSVRHFDTTKNYYVVKHYKIRTLDNNLGFYISNRSKFPNISSLIKYYQTNTDGLCCKLTLSCPQRHKPPIQFKDIEVSRDCIRLERVLGNGSFGEVYLGKWN--NSVEVAVKQLKPNSMDRSRFIAEAELMHKLNHPRIVQILGVCTQPPEQPVFIITELMANGALLNYLRSPEGQKLRLNEMLDMMSQIAEGMAYLESRNFVHRDLRAANILVDEDLSVKVADFGLARVT---DDVYNADTGTKFPIKWTAPEAGMQRRFSVKSDVWSFGVLMYEIVTYGRTPYPGIPNRQVLDEVSK-GYRLPNPAGG-----KIVCPDELYAIKLKCWDAYPENRPTFSHLQDIFEHWEINAESQY 515
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000060646.1 (SMESG000060646.1) HSP 1 Score: 390.578 bits (1002), Expect = 1.203e-130 Identity = 208/459 (45.32%), Postives = 290/459 (63.18%), Query Frame = 3
Query: 204 LKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLG-SGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPEA-VYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
++ALY+Y N LSF DIL+ T ++ W+ A + RT G IP NYV V DGSP+++E ++ + E+++ L +M GTY+IRP SD ALS+R N + + H+ I+ D +YI + F +I LI Y + LT P PR PP QF+E+EV+R ++ LG G FGEVW KW + VA+K+++ + M ++ FL EA++MHKL HP+IV++LGVCT+P PIYIITE M G LL+ L+ + G+ + ++ +++QI+EGMAYLESK +VHRDLRAANILV + VKVADFGLAR+ E+ Y A+ +KFP++WTAPEA + FS KSDVWSFG+L++EI+TYG PY+ +VL+E++ R YRL NP G I C LYN+M+SCW A SE RPTFSFL+ N+ ++ E QY
Sbjct: 30 VRALYTYDIRNPGDLSFAKGDILFVTSNM-NDPWWVARHSRTDAVGYIPSNYV-VVDDGSPTSIEGFFEINHIEADKKLLLMGYSPGTYIIRPSSDSRNCALSIRHFDPERNFYVVKHYKIRTLDNGGYYISHRTPFPDIRTLIAHYTQHTDGLCCRLTEPFPRQHKPPFQFREIEVNRKCITLVRKLGNGSFGEVWLGKWNDIIE--VAVKMMRPNCMDSDTFLGEAQLMHKLHHPRIVQILGVCTEPAGSPIYIITELMAKGALLNFLREEEGQKLTLQDMLLMLSQIAEGMAYLESKCFVHRDLRAANILVSDDLSVKVADFGLARIT---EDEYLADPGTKFPIKWTAPEAGLKRVFSVKSDVWSFGVLMFEIITYGRTPYAGFQNCKVLEEVS-RGYRLPNPQGG-----KIKCPGELYNIMLSCWDATSEKRPTFSFLKDTFENYTIATERQY 475
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000060646.1 (SMESG000060646.1) HSP 1 Score: 389.808 bits (1000), Expect = 3.450e-130 Identity = 206/459 (44.88%), Postives = 293/459 (63.83%), Query Frame = 3
Query: 204 LKALYSYQTNNANQLSFDVNDILYATEDIVGKNWYNAINKRTQLSGMIPYNYVREVVDGSPSNLEYYYNVTRGESERLLQVMSNISGTYLIRPCSDKSKTALSVRVLG-SGNVWNIHHFIIQHNDKQ-WYIIIDSKFNNISDLIDFYKKTPIIKNNCLTVPLPRNQNPPIQFQEMEVSRNNFIKIKVLGKGCFGEVWQAKWGERGSHVVAIKVIQSDMMSNEQFLTEAKVMHKLRHPKIVELLGVCTQPENQPIYIITEFMCNGDLLSLLKSQIGRSFDFKKLIDIIAQISEGMAYLESKLYVHRDLRAANILVDANFMVKVADFGLARVLQQDEESYTANE-SKFPVRWTAPEA-VYGTFSTKSDVWSFGILIYEIVTYGAMPYSTMSTKEVLDEITKRNYRLSNPNGAVFGSNVIMCTTPLYNLMMSCWHAQSENRPTFSFLQYELSNWDVSAEPQY 1568
++ALY+Y +NA L+F DI+ + D+ + W+ A ++ +G IP NYV V DG+P++ E ++++ E++R L +M N GTY+IRP SD ALS+R N + + H+ I+ D +YI + F +I LI Y + LT P PR PP QF+E+EV+R ++ LG G FGEVW KW + VA+K+++ + M ++ FL EA++MHKL HP+IV++LGVCT+P PIYIITE M G LL+ L+ + G+ + ++ +++QI+EGMAYLESK +VHRDLRAANILV + VKVADFGLAR+ E+ Y A+ +KFP++WTAPEA + FS KSDVWSFG+L++EI+TYG PY+ +VL+E++ R YRL NP G I C LYN+M+SCW A SE RPTFSFL+ N+ ++ E QY
Sbjct: 42 VRALYNYNIHNAGDLAFCKGDIMVVSSDL-NEPWWFATHQGNFQTGYIPSNYV-SVDDGTPTSHEAWFDIIHSEADRKLLLMGNPKGTYIIRPSSDSRNCALSIRHFDPERNFYVVKHYKIRTLDNGGYYISHRTPFPDIRTLIAHYTQHTDGLCCRLTEPFPRQHKPPFQFREIEVNRKCITLVRKLGNGSFGEVWLGKWNDIIE--VAVKMMRPNCMDSDTFLGEAQLMHKLHHPRIVQILGVCTEPAGSPIYIITELMAKGALLNFLREEEGQKLTLQDMLLMLSQIAEGMAYLESKCFVHRDLRAANILVSDDLSVKVADFGLARIT---EDEYLADPGTKFPIKWTAPEAGLKRVFSVKSDVWSFGVLMFEIITYGRTPYAGFQNCKVLEEVS-RGYRLPNPQGG-----KIKCPGELYNIMLSCWDATSEKRPTFSFLKDTFENYTIATERQY 487 The following BLAST results are available for this feature:
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Tyrosine-protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30004557 ID=SMED30004557|Name=Tyrosine-protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1690bpback to top protein sequence of SMED30004557-orf-1 >SMED30004557-orf-1 ID=SMED30004557-orf-1|Name=SMED30004557-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=507bp MGNLAFRKRGKSDKFKSKNQSCLSQSVDDLTPSSPTTKQTKPNTNYTVLKback to top Annotated Terms
The following terms have been associated with this transcript:
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