Tetraspanin

Overview
NameTetraspanin
Smed IDSMED30004488
Length (bp)846
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Tetraspanin (SMED30004488) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Tetraspanin (SMED30004488) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30004488

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cephalic gangliaSMED30004488h1SMcG0000885 dd_Smed_v4_6501_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30004488h1SMcG0000885 dd_Smed_v4_6501_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30004488h1SMcG0000885 Contig46915uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30004488h1SMcG0000885 Contig46915newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Tetraspanin vs. Ensembl Human
Match: CD81 (CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701])

HSP 1 Score: 75.0998 bits (183), Expect = 2.046e-15
Identity = 69/230 (30.00%), Postives = 110/230 (47.83%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQ-----YLSIDEH------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPL-----SCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKF 726
            K IKY LF FN + ++ G VI  V ++ R   Q     YL + +       + G Y+ I +G ++    FLGCYGAI ES CLL  F   +  +F   +AAG+W   +K +I K +     + + +  V+    +   ++      L CCG  S L  +    L       G++ I+   K+ CH+ I +     +  I   AI V +IM+  MI S++LCC I+ +  +
Sbjct:    8 KCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGS-STLTALTTSVLKNNLCPSGSNIISNLFKEDCHQKIDDLFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY 236          
BLAST of Tetraspanin vs. Ensembl Human
Match: CD9 (CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709])

HSP 1 Score: 73.1738 bits (178), Expect = 9.179e-15
Identity = 69/222 (31.08%), Postives = 114/222 (51.35%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEH---------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            K IKY LF FN I ++ GI + ++G++ R   Q  SI E          +TG Y+ I  G ++ +  FLGC GA+ ES C+L LF   +  IF + +AA +W  +HK ++ K++     +   K+   T  + Q + +  I   L CCG+   ++      +    D +   T K C ++IKE      + I  + I + ++M+ GMI S++LCCAI+   +
Sbjct:    8 KCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDTYNKLK--TKDEPQRETLKAIHYALNCCGLAGGVEQF-ISDICPKKDVLETFTVKSCPDAIKEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRNRE 226          
BLAST of Tetraspanin vs. Ensembl Human
Match: CD9 (CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709])

HSP 1 Score: 73.1738 bits (178), Expect = 9.179e-15
Identity = 69/222 (31.08%), Postives = 114/222 (51.35%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEH---------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            K IKY LF FN I ++ GI + ++G++ R   Q  SI E          +TG Y+ I  G ++ +  FLGC GA+ ES C+L LF   +  IF + +AA +W  +HK ++ K++     +   K+   T  + Q + +  I   L CCG+   ++      +    D +   T K C ++IKE      + I  + I + ++M+ GMI S++LCCAI+   +
Sbjct:    8 KCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDTYNKLK--TKDEPQRETLKAIHYALNCCGLAGGVEQF-ISDICPKKDVLETFTVKSCPDAIKEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRNRE 226          
BLAST of Tetraspanin vs. Ensembl Human
Match: CD9 (CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709])

HSP 1 Score: 73.1738 bits (178), Expect = 9.179e-15
Identity = 69/222 (31.08%), Postives = 114/222 (51.35%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEH---------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            K IKY LF FN I ++ GI + ++G++ R   Q  SI E          +TG Y+ I  G ++ +  FLGC GA+ ES C+L LF   +  IF + +AA +W  +HK ++ K++     +   K+   T  + Q + +  I   L CCG+   ++      +    D +   T K C ++IKE      + I  + I + ++M+ GMI S++LCCAI+   +
Sbjct:    8 KCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDTYNKLK--TKDEPQRETLKAIHYALNCCGLAGGVEQF-ISDICPKKDVLETFTVKSCPDAIKEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRNRE 226          
BLAST of Tetraspanin vs. Ensembl Human
Match: CD81 (CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701])

HSP 1 Score: 71.2478 bits (173), Expect = 1.588e-14
Identity = 46/158 (29.11%), Postives = 75/158 (47.47%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPL-----SCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKF 726
            CYGAI ES CLL  F   +  +F   +AAG+W   +K +I K +     + + +  V+    +   ++      L CCG  S L  +    L       G++ I+   K+ CH+ I +     +  I   AI V +IM+  MI S++LCC I+ +  +
Sbjct:    9 CYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGS-STLTALTTSVLKNNLCPSGSNIISNLFKEDCHQKIDDLFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY 165          
BLAST of Tetraspanin vs. Ensembl Celegans
Match: tsp-9 (Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q18177])

HSP 1 Score: 46.595 bits (109), Expect = 7.455e-6
Identity = 39/149 (26.17%), Postives = 68/149 (45.64%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKE 714
            C GA  ESP LL LF  +I  +  V + A ++A+ ++++    I   L +       ++AT +  K +  IQN  QCCG  +           CG +   +S    C + I   ++     I+ +A  +  I L  ++ S +LC + +E
Sbjct:   86 CCGAGCESPVLLGLFIFIIVILTAVELGATVFAMTNREEFVSSIQQVLKK-------SSATYELRKNIKPIQNVFQCCGATAQTQNRYIQDGLCGPE--PLSAPVNCFDRISHMVQSWGESIVVVAFLLLAIELFAILFSCILCRSSQE 225          
BLAST of Tetraspanin vs. Ensembl Celegans
Match: tsp-9 (Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q18177])

HSP 1 Score: 46.595 bits (109), Expect = 7.455e-6
Identity = 39/149 (26.17%), Postives = 68/149 (45.64%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKE 714
            C GA  ESP LL LF  +I  +  V + A ++A+ ++++    I   L +       ++AT +  K +  IQN  QCCG  +           CG +   +S    C + I   ++     I+ +A  +  I L  ++ S +LC + +E
Sbjct:   86 CCGAGCESPVLLGLFIFIIVILTAVELGATVFAMTNREEFVSSIQQVLKK-------SSATYELRKNIKPIQNVFQCCGATAQTQNRYIQDGLCGPE--PLSAPVNCFDRISHMVQSWGESIVVVAFLLLAIELFAILFSCILCRSSQE 225          
BLAST of Tetraspanin vs. Ensembl Celegans
Match: tsp-6 (Tetraspanin [Source:UniProtKB/TrEMBL;Acc:G4RWX0])

HSP 1 Score: 46.2098 bits (108), Expect = 9.206e-6
Identity = 43/158 (27.22%), Postives = 76/158 (48.10%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLS-EIVGKISVNTATKDQI-KIMDKIQNELQCCGVISHLDYVEKP--PLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKFA 729
            C G+  ES C + ++ +++  +FVV + A +    +K  + +        E+V K +    T+ QI +++D+IQ+ LQCCG     DY+     P SC    I    + GC   I    + ++  +  + I +  + LL MI S ++  A+KE    A
Sbjct:   87 CCGSCCESICAISIYFILVLILFVVEVVAIVLYFVNKTNLQQGFQTIWRDELVSKYN----TQQQIHQVLDQIQSSLQCCGASGCSDYIPYGAFPTSCQCATI---QQAGCATVIWNSFESSLIYVAFVGIIILFVELLAMIFSCIIIGAVKEKRSQA 237          
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp47F (gene:FBgn0033629 transcript:FBtr0088151)

HSP 1 Score: 64.6994 bits (156), Expect = 5.181e-12
Identity = 41/115 (35.65%), Postives = 59/115 (51.30%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYV-----EKPPLSCGNDYITISTKKGCHES 597
            C+GAI ESP LLI F++++  IF+V +A G+ A   K+ ++  + NSL E     S+  +  +     D IQ +L CCGV S  D+      +  P SC       ST   C ES
Sbjct:   71 CFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQE-----SIKRSNSEDTMAWDNIQQKLMCCGVDSPADWRTLSANKTLPGSCCQPQYIDSTVGHCLES 180          
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp74F (gene:FBgn0036769 transcript:FBtr0075155)

HSP 1 Score: 60.077 bits (144), Expect = 2.202e-10
Identity = 59/229 (25.76%), Postives = 116/229 (50.66%), Query Frame = 1
Query:   67 RLAASFKFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSI---DEHFTGA-YXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPL--SCGND-----------YITIST--KKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIML 696
            R+    +F+KY+LF  N + F+ G ++F + ++  +   +++       F+GA Y+ +   +II + SFLGC GA  E  CLL+ + +++  +FV ++  G+     ++++ + +     E+   +++  + ++  +  D  Q  LQCCGV +  D+    P+  SC  +           + TI+    +GC      F++ +   I G +I V I+M+ GMI S +L
Sbjct:    6 RMDCCGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLLVTSIIICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQ---EMRSTMALYGSRREITQAWDLTQERLQCCGVDTWHDWNRYGPVPESCCQELFGGQRKECTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLL 231          
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp74F (gene:FBgn0036769 transcript:FBtr0075154)

HSP 1 Score: 60.077 bits (144), Expect = 2.202e-10
Identity = 59/229 (25.76%), Postives = 116/229 (50.66%), Query Frame = 1
Query:   67 RLAASFKFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSI---DEHFTGA-YXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPL--SCGND-----------YITIST--KKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIML 696
            R+    +F+KY+LF  N + F+ G ++F + ++  +   +++       F+GA Y+ +   +II + SFLGC GA  E  CLL+ + +++  +FV ++  G+     ++++ + +     E+   +++  + ++  +  D  Q  LQCCGV +  D+    P+  SC  +           + TI+    +GC      F++ +   I G +I V I+M+ GMI S +L
Sbjct:    6 RMDCCGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLLVTSIIICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQ---EMRSTMALYGSRREITQAWDLTQERLQCCGVDTWHDWNRYGPVPESCCQELFGGQRKECTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLL 231          
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp29Fa (gene:FBgn0032074 transcript:FBtr0300289)

HSP 1 Score: 57.3806 bits (137), Expect = 2.176e-9
Identity = 40/171 (23.39%), Postives = 79/171 (46.20%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGK---ISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPP------------------LSCGNDYITISTKK--GCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIK 711
            C+GA+ E+ CL++ FS+++  IF++ +AAG+     +      I  SL+  + +   I+ N  T    K+ D IQ+E +CCGV S+ D++   P                   +C N   +++ +   GC +    ++  +   +    + + I+   G+I +  +   IK
Sbjct:   73 CWGALKENYCLVLSFSVMLAIIFILELAAGISGYVLRNDASDLIKTSLTYSLNEYNSINPNATT----KLWDDIQDEFECCGVTSYNDWITAFPNGDLPISCCNVHVGAVGTFTCNNAQSSVADRHKVGCLDGFSGYISAHAVSLGAAGVVIAILQFFGVIFACYIAREIK 239          
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp29Fa (gene:FBgn0032074 transcript:FBtr0340261)

HSP 1 Score: 57.3806 bits (137), Expect = 2.176e-9
Identity = 40/171 (23.39%), Postives = 79/171 (46.20%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGK---ISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPP------------------LSCGNDYITISTKK--GCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIK 711
            C+GA+ E+ CL++ FS+++  IF++ +AAG+     +      I  SL+  + +   I+ N  T    K+ D IQ+E +CCGV S+ D++   P                   +C N   +++ +   GC +    ++  +   +    + + I+   G+I +  +   IK
Sbjct:   73 CWGALKENYCLVLSFSVMLAIIFILELAAGISGYVLRNDASDLIKTSLTYSLNEYNSINPNATT----KLWDDIQDEFECCGVTSYNDWITAFPNGDLPISCCNVHVGAVGTFTCNNAQSSVADRHKVGCLDGFSGYISAHAVSLGAAGVVIAILQFFGVIFACYIAREIK 239          
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: cd9a (CD9 molecule a [Source:ZFIN;Acc:ZDB-GENE-030131-1175])

HSP 1 Score: 82.0333 bits (201), Expect = 3.480e-18
Identity = 73/222 (32.88%), Postives = 116/222 (52.25%), Query Frame = 1
Query:   91 IKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDE-------HFTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVG--KISVNTATKDQIKIMDKIQNELQCCGVISHLDYV--EKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            +KY +F FN I +I G  + +VG++ R   +  S+ E        +TG Y+ I  G ++ +  F GC GAI ESPC+L LF   +  IF V +AAG+W  +++ K+ + I     +     + S   A K  +++    Q+ L CCG   ++     E  P   G D + I   K C ++I E     ++ I G+ I  G+IM+ GMI S+MLCCAI++  +
Sbjct:   11 VKYLMFVFNFIFWIAGTAVLAVGLWLRFDPKTKSLFEGENSPYVFYTGVYILIAAGALMMVVGFFGCCGAIQESPCMLGLFFFFLLVIFAVEVAAGIWGFSNQTKVTEDITTFYRQTYDTYQQSKQEALKKTLRL---FQHGLNCCGPSGNMQESLDETCPKKEGLDNLII---KSCPDAIDEVFNSKLHIIGGVGIATGVIMIFGMIFSMMLCCAIRKTRE 226          
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: cd9a (CD9 molecule a [Source:ZFIN;Acc:ZDB-GENE-030131-1175])

HSP 1 Score: 81.2629 bits (199), Expect = 6.542e-18
Identity = 73/224 (32.59%), Postives = 117/224 (52.23%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEH-------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVG--KISVNTATKDQIKIMDKIQNELQCCGVISHLDYV--EKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            K IKY++F  N + +I G  + +VG++ R   +  S+ E        +TG Y+ I  G ++ +  F GC GAI ESPC+L LF   +  IF V +AAG+W  +++ K+ + I     +     + S   A K  +++    Q+ L CCG   ++     E  P   G D + I   K C ++I E     ++ I G+ I  G+IM+ GMI S+MLCCAI++  +
Sbjct:    8 KCIKYSMFLLNSVFWIAGTAVLAVGLWLRFDPKTKSLFEGENSPYVFYTGVYILIAAGALMMVVGFFGCCGAIQESPCMLGLFFFFLLVIFAVEVAAGIWGFSNQTKVTEDITTFYRQTYDTYQQSKQEALKKTLRL---FQHGLNCCGPSGNMQESLDETCPKKEGLDNLII---KSCPDAIDEVFNSKLHIIGGVGIATGVIMIFGMIFSMMLCCAIRKTRE 225          
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: tspan4b (tetraspanin 4b [Source:ZFIN;Acc:ZDB-GENE-070410-127])

HSP 1 Score: 77.411 bits (189), Expect = 1.715e-16
Identity = 47/162 (29.01%), Postives = 84/162 (51.85%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEK------PPLSCGNDYITIS-TKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKFAN 732
            C GA+ E  CLL+ F +++  + +  +   L    + +++DKK  + L E +   S N   +   K  D +Q   +CCGV +H D+  K      P   C ND  +    ++ C+E  K++L  NI  ++G  + +GI+ LL ++ S+++ C I  AEK+ +
Sbjct:   74 CLGALKEQKCLLLTFFVILLILVLTEVVLILVLSLYHEELDKKAKDDLREGMKGYSKNDGLR---KSWDNMQMIFKCCGVSNHTDWHNKTSDGKLPGSCCSNDPSSCRHWEEPCYEKAKQWLLTNITSVLGFGVCIGIVQLLALVFSMLMYCQILRAEKYMD 232          
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: tspan4b (tetraspanin 4b [Source:ZFIN;Acc:ZDB-GENE-070410-127])

HSP 1 Score: 77.411 bits (189), Expect = 1.821e-16
Identity = 47/162 (29.01%), Postives = 84/162 (51.85%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEK------PPLSCGNDYITIS-TKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKFAN 732
            C GA+ E  CLL+ F +++  + +  +   L    + +++DKK  + L E +   S N   +   K  D +Q   +CCGV +H D+  K      P   C ND  +    ++ C+E  K++L  NI  ++G  + +GI+ LL ++ S+++ C I  AEK+ +
Sbjct:   74 CLGALKEQKCLLLTFFVILLILVLTEVVLILVLSLYHEELDKKAKDDLREGMKGYSKNDGLR---KSWDNMQMIFKCCGVSNHTDWHNKTTDGKLPGSCCSNDPSSCRHWEEPCYEKAKQWLLTNITSVLGFGVCIGIVQLLALVFSMLMYCQILRAEKYMD 232          
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: cd81a (CD81 molecule a [Source:ZFIN;Acc:ZDB-GENE-000831-5])

HSP 1 Score: 72.0182 bits (175), Expect = 1.798e-14
Identity = 73/227 (32.16%), Postives = 110/227 (48.46%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSI-DEHFTGA----------YXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGK-ISVNTATKDQIKIMDKIQNE-LQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKF 726
            K IKY LFFFN I ++ G VI  V ++ R   +  S+ D  + G           Y+ I +G ++    FLGCYGAI ES CLL  F   +  +F   +AAG+W   +K KI K++      +  K  + NT  K+    + K+ +E LQCCG  +    +    L+        +    CH  IK      I+ I   A+ V +IM+  MI S++LCC I+ +  +
Sbjct:   10 KCIKYMLFFFNFIFWLAGCVILGVSLWLRHDTKTSSLLDLKYEGTESPTTFYISVYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFACLVLLFACEVAAGIWGFMNKDKISKEVIGFYDSVYDKGATYNTDNKNPATAVLKVFHETLQCCGKGNLFTAIVDRWLTDTCPEHLRTNAVDCHTEIKNLFTDKISLIGIAALVVAVIMIFEMIFSMVLCCGIRNSPVY 236          
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: cd9 (CD9 protein [Source:NCBI gene;Acc:549743])

HSP 1 Score: 78.1814 bits (191), Expect = 1.467e-16
Identity = 67/222 (30.18%), Postives = 109/222 (49.10%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDE-------HFTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKI--SVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            K IKY LF FN I ++ G  +  +G++ R   Q  ++ E        +TG Y+ I  G ++ +  FLGC GAI ES C+L LF   +  IF V +AAG+W   +K K+  ++     +   K   S + A KD +K    I   L CCG+   L+             +   + + C  +I++      + +  + I + +IM+ GMI S++LCCAI+   +
Sbjct:    8 KCIKYLLFAFNFIFWLAGTAVLGIGLWLRFDPQTKAMFEADQNTGAFYTGVYILIGAGALMMLVGFLGCCGAIQESECMLGLFFAFLLVIFAVEIAAGIWGFTNKDKVVDELKTFYKDTYTKYMKSNDNALKDTLK---AIHLALNCCGMTGVLEATVTDICPNNQGIVGALSAQSCPAAIEDVFTTKFHIVGAVGIGIAVIMIFGMIFSMVLCCAIRNNRE 226          
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: tns1 (tensin 1 [Source:Xenbase;Acc:XB-GENE-957068])

HSP 1 Score: 65.855 bits (159), Expect = 3.795e-12
Identity = 72/228 (31.58%), Postives = 112/228 (49.12%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSI------DEH-----FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQ--IKIMDKIQNELQCCGVISHLDYVEK------PPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIK 711
            K IKY LF FN I ++ G VI  V ++ R   Q  ++      D+H     + G Y+ I +G ++    FLGCYGAI ES CLL  F   +  +F   +AAG+W   ++ ++ K++    SE+    +  T  + Q  + ++      LQCCG  S   YV        P  S   + ITI   + CH+ I       +  +   A+ V +IM++ MI S++LCC I+
Sbjct:    8 KCIKYLLFVFNFIFWLAGGVILGVALWLRHDPQTSNLLFQQFEDKHAPGTFYIGVYIIIAVGAVMMFVGFLGCYGAIQESQCLLGTFFACLVILFACEVAAGIWGFVNRDQVSKEMRLFYSEVYQHATTGTKEQQQKALPVLKAFHETLQCCGDASLKKYVTMSITDMCPKRSNILEQITI---EDCHQKIDVLFSTKLYLVGIAAVVVAVIMIIEMIFSMVLCCGIR 232          
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: trip4 (thyroid hormone receptor interactor 4 [Source:Xenbase;Acc:XB-GENE-974186])

HSP 1 Score: 65.4698 bits (158), Expect = 5.760e-12
Identity = 46/164 (28.05%), Postives = 80/164 (48.78%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLS----------------CGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIK 711
            C GA+ E+ C++  F++V+  IF+V +AA + A  +K K+     +S     G +  N  TKD    +D +Q E QCCG I+  D+ +  P +                CG   I     +GC   I +++K N+  + G+A+ + +  +LG+   +  CC +K
Sbjct:   67 CCGALKENYCMVTTFAVVLVLIFLVEIAAAIAAYVYKDKLRTAFEDSFKN--GMVHYND-TKDIADSIDLLQKEFQCCGAINSTDWRQYAPFTGTNTVPDSCCKNITAGCGKGPIANINSEGCATGIDQWVKKNVGIVAGVALGIALFEILGI---VFACCLMK 224          
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: trip4 (thyroid hormone receptor interactor 4 [Source:Xenbase;Acc:XB-GENE-974186])

HSP 1 Score: 65.0846 bits (157), Expect = 8.432e-12
Identity = 46/164 (28.05%), Postives = 80/164 (48.78%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLS----------------CGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIK 711
            C GA+ E+ C++  F++V+  IF+V +AA + A  +K K+     +S     G +  N  TKD    +D +Q E QCCG I+  D+ +  P +                CG   I     +GC   I +++K N+  + G+A+ + +  +LG+   +  CC +K
Sbjct:   80 CCGALKENYCMVTTFAVVLVLIFLVEIAAAIAAYVYKDKLRTAFEDSFKN--GMVHYND-TKDIADSIDLLQKEFQCCGAINSTDWRQYAPFTGTNTVPDSCCKNITAGCGKGPIANINSEGCATGIDQWVKKNVGIVAGVALGIALFEILGI---VFACCLMK 237          
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: ENSXETT00000022335.1 (tetraspanin-4-like [Source:NCBI gene;Acc:101734690])

HSP 1 Score: 60.077 bits (144), Expect = 3.674e-10
Identity = 39/169 (23.08%), Postives = 83/169 (49.11%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKI------DKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKP---PLSCGNDYIT-------ISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKF 726
            C GA++E  CLL+ F +++  IF++ M +    + + ++       D K G  L    G + +  A        D +Q E +CCGV +  D++E     P +C  ++         +  ++ C+  ++ +++ NI  +    I + ++ + G+I S+++ C + +AEK+
Sbjct:   72 CLGAVTEHRCLLLTFFVILLIIFLLEMISMALFLTYTEQFHNYAQEDLKKGLQLYNTTGNLGLTNA-------WDIVQTEFRCCGVKNATDWLESKGSVPHTCCVEHSPACKSNPKLWWEEACYNKVRNWVESNIRSVGIFGICILVVQVFGLIFSMLMYCQVVKAEKY 233          
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Cd9 (CD9 antigen [Source:MGI Symbol;Acc:MGI:88348])

HSP 1 Score: 81.6481 bits (200), Expect = 6.202e-18
Identity = 69/221 (31.22%), Postives = 114/221 (51.58%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEH-------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTK-KGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            K IKY LF FN I ++ GI + ++G++ R   Q  SI E        +TG Y+ I  G ++ +  FLGC GA+ ES C+L LF   +  IF + +AA +W   HK ++ K++     +   K+   +  + Q + +  I   L CCG+   L+       +C    +  S + K C E+I E      + I  + I + ++M+ GMI S++LCCAI+ + +
Sbjct:    8 KCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQENNHSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAVWGYTHKDEVIKELQEFYKDTYQKL--RSKDEPQRETLKAIHMALDCCGIAGPLEQFISD--TCPKKQLLESFQVKPCPEAISEVFNNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRSRE 224          
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Cd81 (CD81 antigen [Source:MGI Symbol;Acc:MGI:1096398])

HSP 1 Score: 75.0998 bits (183), Expect = 1.600e-15
Identity = 64/229 (27.95%), Postives = 105/229 (45.85%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSI-----------DEHFTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCG----VISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKF 726
            K IKY LF FN + ++ G VI  V ++ R   Q  S+           +  + G Y+ I +G ++    FLGCYGAI ES CLL  F   +  +F   +AAG+W   +K +I K +     + + +  ++    +   ++      L CCG           +       G + +T   ++ CH+ I E     +  I   AI V +IM+  MI S++LCC I+ +  +
Sbjct:    8 KCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTSLLYLELGNKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVMDDDANNAKAVVKTFHETLNCCGSNALTTLTTTILRNSLCPSGGNILTPLLQQDCHQKIDELFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY 236          
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Cd82 (CD82 antigen [Source:MGI Symbol;Acc:MGI:104651])

HSP 1 Score: 68.9366 bits (167), Expect = 4.058e-13
Identity = 47/180 (26.11%), Postives = 83/180 (46.11%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKP----------PLSCGN-----------------DYITIS---------TKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLC 699
            C GA++E  CLL L+ + +  I +  +  G+    +  K+ K++GN++ +I+   + N AT  + +  D +Q +++CCG +SH ++ E            P SC                   D  T+S           +GC E  + +L+ N   ++G+   V +I LLG+  SI LC
Sbjct:   74 CIGAVNEVRCLLGLYFVFLLLILIAQVTVGVLFYFNADKLKKEMGNTVMDIIRNYTAN-ATSSREEAWDYVQAQVKCCGWVSHYNWTENEELMGFTKTTYPCSCEKIKEEDNQLIVKKGFCEADNSTVSENNPEDWPVNTEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLFLSICLC 252          
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Cd82 (CD82 antigen [Source:MGI Symbol;Acc:MGI:104651])

HSP 1 Score: 68.9366 bits (167), Expect = 4.058e-13
Identity = 47/180 (26.11%), Postives = 83/180 (46.11%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKP----------PLSCGN-----------------DYITIS---------TKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLC 699
            C GA++E  CLL L+ + +  I +  +  G+    +  K+ K++GN++ +I+   + N AT  + +  D +Q +++CCG +SH ++ E            P SC                   D  T+S           +GC E  + +L+ N   ++G+   V +I LLG+  SI LC
Sbjct:   74 CIGAVNEVRCLLGLYFVFLLLILIAQVTVGVLFYFNADKLKKEMGNTVMDIIRNYTAN-ATSSREEAWDYVQAQVKCCGWVSHYNWTENEELMGFTKTTYPCSCEKIKEEDNQLIVKKGFCEADNSTVSENNPEDWPVNTEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLFLSICLC 252          
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Cd82 (CD82 antigen [Source:MGI Symbol;Acc:MGI:104651])

HSP 1 Score: 68.9366 bits (167), Expect = 4.058e-13
Identity = 47/180 (26.11%), Postives = 83/180 (46.11%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKP----------PLSCGN-----------------DYITIS---------TKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLC 699
            C GA++E  CLL L+ + +  I +  +  G+    +  K+ K++GN++ +I+   + N AT  + +  D +Q +++CCG +SH ++ E            P SC                   D  T+S           +GC E  + +L+ N   ++G+   V +I LLG+  SI LC
Sbjct:   74 CIGAVNEVRCLLGLYFVFLLLILIAQVTVGVLFYFNADKLKKEMGNTVMDIIRNYTAN-ATSSREEAWDYVQAQVKCCGWVSHYNWTENEELMGFTKTTYPCSCEKIKEEDNQLIVKKGFCEADNSTVSENNPEDWPVNTEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLFLSICLC 252          
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|P30932|CD9_BOVIN (CD9 antigen OS=Bos taurus OX=9913 GN=CD9 PE=2 SV=2)

HSP 1 Score: 81.6481 bits (200), Expect = 3.764e-17
Identity = 68/217 (31.34%), Postives = 112/217 (51.61%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEH-------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKE 714
            K IKY LF FN I ++ GI + SVG++ R   Q  SI E        +TG Y+ I  G ++ +  FLGC GA+ ES C+L LF   +  IF + +AA +W  +HK+++ K++     +   K+      + Q + +  I   L CCG+    +          N   ++ T+  C E+I E  +   + I  + I + ++M+ GM+ S++LCCAI+ 
Sbjct:    8 KCIKYLLFGFNFIFWLAGIAVLSVGLWLRFDSQTKSIFEQENNDSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFSFLLVIFAIEVAAAIWGYSHKEEVIKEVQKFYEDTYNKL--KNKDEPQRETLKAIHIALDCCGLTGVPEQFLTDTCPPKNLIDSLKTRP-CPEAIDEIFRSKFHIIGAVGIGIAVVMIFGMVFSMILCCAIRR 221          
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|P40240|CD9_MOUSE (CD9 antigen OS=Mus musculus OX=10090 GN=Cd9 PE=1 SV=2)

HSP 1 Score: 81.6481 bits (200), Expect = 4.338e-17
Identity = 69/221 (31.22%), Postives = 114/221 (51.58%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEH-------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTK-KGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            K IKY LF FN I ++ GI + ++G++ R   Q  SI E        +TG Y+ I  G ++ +  FLGC GA+ ES C+L LF   +  IF + +AA +W   HK ++ K++     +   K+   +  + Q + +  I   L CCG+   L+       +C    +  S + K C E+I E      + I  + I + ++M+ GMI S++LCCAI+ + +
Sbjct:    8 KCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQENNHSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAVWGYTHKDEVIKELQEFYKDTYQKL--RSKDEPQRETLKAIHMALDCCGIAGPLEQFISD--TCPKKQLLESFQVKPCPEAISEVFNNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRSRE 224          
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|O97703|CD81_CHLAE (CD81 antigen OS=Chlorocebus aethiops OX=9534 GN=CD81 PE=2 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 1.086e-15
Identity = 71/230 (30.87%), Postives = 110/230 (47.83%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQ-----YLSIDEH------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPL-----SCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKF 726
            K IKY LF FN + ++ G VI  V ++ R   Q     YL + +       + G Y+ I +G ++    FLGCYGAI ES CLL  F   +  +F   +AAG+W   +K +I K +     + + +  V+    +   ++      L CCG  S L  +    L       G++ I+   KK CH+ I E     +  I   AI V +IM+  MI S++LCC I+ +  +
Sbjct:    8 KCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGS-STLAALTTSVLKNNLCPSGSNIISNLLKKDCHQKIDELFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY 236          
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|P40241|CD9_RAT (CD9 antigen OS=Rattus norvegicus OX=10116 GN=Cd9 PE=1 SV=2)

HSP 1 Score: 77.411 bits (189), Expect = 1.475e-15
Identity = 67/221 (30.32%), Postives = 112/221 (50.68%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEH-------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTK-KGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            K IKY LF FN I ++ GI + ++G++ R   Q  SI E        +TG Y+ I  G ++ +  FLGC GA+ ES C+L LF   +  IF + +AA +W   HK ++ K++     +   K+      + Q + +  I   L CCG+   ++        C    +  S + K C ++I E      + I  + I + ++M+ GMI S++LCCAI+ + +
Sbjct:    8 KCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNHSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAVWGYTHKDEVIKELQEFYKDTYQKL--RNKDEPQRETLKAIHMALNCCGIAGGVEQFISDI--CPKKQVLESFQVKSCPDAIDEVFHSKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRSRE 224          
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|Q8WMQ3|CD9_PIG (CD9 antigen OS=Sus scrofa OX=9823 GN=CD9 PE=2 SV=3)

HSP 1 Score: 76.2554 bits (186), Expect = 3.870e-15
Identity = 68/220 (30.91%), Postives = 117/220 (53.18%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEH-------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            K IKY LF FN I ++ GI + ++G++ R   Q  SI E        +TG Y+ I  G ++ +  FLGC GA+ ES C+L LF   +  IF + +AA +W  +HK ++ K++ +   +   K+        Q + +  I   L CCG++  ++ +    +    D ++    K C E+IKE  +   + I  + I + ++M+ GMI S++LCCAI+ + +
Sbjct:    8 KCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQENNNSSFYTGVYILIGAGALMMVVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDQVIKEVQDFYRDTYNKL--KGKDDPQRETLKAIHYALDCCGLMGEVEQL-LADICPQRDVLSSLPMKPCPEAIKEVFQNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRSRE 224          
BLAST of Tetraspanin vs. TrEMBL
Match: I3NQF9 (Tetraspanin OS=Spirometra erinaceieuropaei OX=99802 GN=TSP16 PE=2 SV=1)

HSP 1 Score: 143.28 bits (360), Expect = 5.143e-38
Identity = 92/225 (40.89%), Postives = 139/225 (61.78%), Query Frame = 1
Query:   55 MARIRLAASFKFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEHF----TGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYV-EKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKE 714
            M +I L   FK +KYALF F L++++ G++ F  GI AR +  +  +D+HF    +GA L I +G  I + + LGC GAI ES C+L+ F   IF  F +LMAAGLWA+A + ++   + NSL ++V    +N    D IK++D IQ +  CCGV   +D+V +K P SCG     IS + GCH  I++  + N++ I G+ I   +IM+ GM+ S+MLCC+++E
Sbjct:    1 MTKISLTCCFKCVKYALFVFCLVAWLLGLIAFVWGIVARTTGSFGPLDQHFPAVNSGANLLITVGFFIMLVATLGCCGAIRESQCMLMSFFFSIFMCFTLLMAAGLWAVAWQPRLGVYLFNSLEKLVNNYKLN-EDPDDIKLLDFIQTKFVCCGVTGAVDFVPKKAPESCGGTTKEISQRPGCHSMIQQAGQDNLSTITGIGIGFAMIMICGMVFSLMLCCSLRE 224          
BLAST of Tetraspanin vs. TrEMBL
Match: A0A0X3Q4N9 (Tetraspanin OS=Schistocephalus solidus OX=70667 GN=CD9 PE=3 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 5.920e-35
Identity = 90/225 (40.00%), Postives = 136/225 (60.44%), Query Frame = 1
Query:   55 MARIRLAASFKFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEHF----TGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYV-EKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKE 714
            M +I L   FK +KYALF F L+++I G+  F  GI AR +  +  +D+H     +GA L I +G  I + + LGC GAI ES C+L+ F   IF  F +LMAAGLWA+A + ++   + +SL ++V    +N    D IK+++ IQ +  CCGV   +D+V +K P SCG     IS + GCH  I +  + N++ I G+ +   +IM+ GM+ S+MLCCA++E
Sbjct:    1 MTKISLTCCFKCVKYALFVFCLVAWILGLTAFIWGIVARTTGSFGPLDQHLPAVNSGANLLITVGFFIMLVATLGCCGAIRESQCMLMSFFFSIFMCFTLLMAAGLWAVAWQPRLGVHLFSSLEKLVYNYKLNE-EPDDIKLLEFIQTKFACCGVTGAVDFVPKKAPASCGVTTKEISQRPGCHSKILQAGQDNLSTIAGIGMGFAMIMICGMVFSLMLCCALRE 224          
BLAST of Tetraspanin vs. TrEMBL
Match: A0A504YFQ9 (Tetraspanin OS=Fasciola gigantica OX=46835 GN=FGIG_05029 PE=3 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 1.202e-30
Identity = 95/225 (42.22%), Postives = 130/225 (57.78%), Query Frame = 1
Query:   55 MARIRLAASFKFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEHF----TGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKP-PLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKE 714
            M  I L   FK IKY++F F LI+++ G++   VGI AR+S  +  +D H     +GA L I +G  I I  FLGC G I ES C+L  F + +FF F +LMAAGLWA+A   K+D  +   L + V     +    +  K+MD +Q +  CCGV S  DY  KP P SCG      S   GCH  + E  K N++ I G+ I   +IM+LGM+CS+MLCCA++E
Sbjct:    1 MPSISLTGWFKCIKYSMFAFCLIAWLIGLITLIVGIVARVSGSFGPLDAHIPAVHSGANLLIAVGFFIMIMGFLGCCGTIRESQCMLFSFFLFVFFCFTLLMAAGLWAVAWSSKLDDYLYRYLEKQVVNYREHETQNESTKLMDFLQRKYTCCGVSSAADYGSKPVPRSCGESASVYSKLSGCHAVLVEVCKSNLSLICGIGIGFALIMILGMVCSMMLCCALRE 225          
BLAST of Tetraspanin vs. TrEMBL
Match: U6JEW1 (Tetraspanin OS=Echinococcus granulosus OX=6210 GN=EGR_09512 PE=3 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 1.248e-30
Identity = 87/225 (38.67%), Postives = 133/225 (59.11%), Query Frame = 1
Query:   55 MARIRLAASFKFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEHF----TGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVE-KPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKE 714
            MA++ +   FK +KYALF F L+++I G+V F  GI AR +  +  ++ H     +GA + I +G II    FLGC GAI ES  LL+ F   IF  F +LMAAGLWA+A + ++   + NSL ++V     ++   D IK++D IQN+  CCG +   D+     P SCG+     + + GC   I +  + N++ + G+ I  G+IM+ GM+ S+MLCCA++E
Sbjct:    1 MAKVSVTGCFKCVKYALFAFCLVAWIIGLVAFVWGIVARATGHFGPLESHIPAATSGANILIAVGFIIMFVGFLGCCGAIRESQFLLMAFFFSIFLCFSLLMAAGLWAVAWQPRLPVYLHNSLEKLVRSYKTDS-NSDDIKLLDFIQNKFACCGAVGIEDFSGLHVPASCGSTITEQTQRPGCQPKILQSGQENLSTMAGIGIGFGVIMICGMVFSLMLCCALRE 224          
BLAST of Tetraspanin vs. TrEMBL
Match: A0A5K3F6K1 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 123.635 bits (309), Expect = 1.560e-30
Identity = 87/225 (38.67%), Postives = 133/225 (59.11%), Query Frame = 1
Query:   55 MARIRLAASFKFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEHF----TGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKP-PLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKE 714
            MA++ +   FK +KYALF F L+S+I G+V F  GI AR +  +  ++ H     +GA L I +G II    FLGC GAI ES  LL+ F   +F  F +LMAAGLWA+A + ++   + NSL ++V     +   +D + I++ IQN+  CCG +  +DY   P P SCG+ +   + + GC   I +  + N++ + G+ I    IM+ GM+ S+MLCCA++E
Sbjct:    1 MAKVSITGCFKCVKYALFAFCLVSWILGLVAFIWGIVARTTGHFGPLEAHMPTVTSGANLLIAVGFIIMFVGFLGCCGAIRESQFLLMAFYFSVFMCFSLLMAAGLWAVAWQPRLPIYLHNSLEKLVKSYKTDGDPED-VNILNFIQNKFVCCGAVGVVDYSNSPVPTSCGSSHQEQTQRPGCQYKILQSGQENLSTMTGIGIGFAAIMIFGMVFSLMLCCALRE 224          
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: cd81a (CD81 molecule [Source:NCBI gene;Acc:103037709])

HSP 1 Score: 74.7146 bits (182), Expect = 1.580e-15
Identity = 75/227 (33.04%), Postives = 112/227 (49.34%), Query Frame = 1
Query:   85 KFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSI-----------DEHFTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTAT--KDQIKIMDKIQNE-LQCCGV--ISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEA 717
            K IKY LFFFN I ++ G VI  V ++ R  ++  S+           +  +   Y+ I +G ++    FLGCYGAI ES CLL  F   +  +F   +AAG+W   HK KI K++ N    +  K    T    KD    + K+ +E LQCCG   ++ +       L    D I +  ++GCH  I+      I  I   A+ V +IM+  MI S++LCC I+ +
Sbjct:    8 KCIKYMLFFFNFIFWLAGCVILGVSLWLRHDQKTSSLLDLKYEDASAPNTFYISVYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFACLVILFACEVAAGIWGFIHKDKISKELINFYDSVYDKGMGQTLQDKKDAAAAVLKVFHETLQCCGKEGVTSIFTGFATDLCPKKDSI-LDIQEGCHSKIRTLFTEKIYLIGIAALVVAVIMIFEMIFSMVLCCGIRNS 233          
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: cd9a (CD9 antigen-like [Source:NCBI gene;Acc:103028636])

HSP 1 Score: 66.2402 bits (160), Expect = 1.673e-12
Identity = 68/228 (29.82%), Postives = 119/228 (52.19%), Query Frame = 1
Query:   70 LAASFKFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDE-------HFTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVN--TATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCG-NDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            L      +KY +F FNL+ ++ G  + +VG++ R   +  ++ E        +TG Y+ I  G ++ +  F GC GAI ESPC+L LF   +  IF V +AAG+W  +++ K+   I    ++       N   A K+ +++   IQ+ L CCG  +  + ++    +C   D +     K C ++I E     ++ I  + I +G+IM+ GM+ S+MLCCAI++  +
Sbjct:    3 LPGGITCVKYLMFIFNLLFWLAGTGVLAVGLWLRFDPKTKNLFEGESSPYVFYTGVYILIAAGALMMVVGFFGCCGAIQESPCMLGLFFFFLLLIFAVEVAAGIWGFSNQSKVVDDITQFYTQTYSNYKDNKQDALKETLRL---IQHRLNCCGPSNTAEDLKILEDTCPKKDILDDLIIKSCPDAIDEVFNSKLHIIGAVGIGIGVIMIFGMVFSMMLCCAIRKTRE 227          
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: cd9a (CD9 antigen-like [Source:NCBI gene;Acc:103028636])

HSP 1 Score: 63.929 bits (154), Expect = 1.010e-11
Identity = 67/221 (30.32%), Postives = 117/221 (52.94%), Query Frame = 1
Query:   91 IKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDE-------HFTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVN--TATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCG-NDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            +KY +F FN I ++ G  + +VG++ R   +  ++ E        +TG Y+ I  G ++ +  F GC GAI ESPC+L LF   +  IF V +AAG+W  +++ K+   I    ++       N   A K+ +++   IQ+ L CCG  +  + ++    +C   D +     K C ++I E     ++ I  + I +G+IM+ GM+ S+MLCCAI++  +
Sbjct:   11 VKYLMFAFNFIFWLAGTGVLAVGLWLRFDPKTKNLFEGESSPYVFYTGVYILIAAGALMMVVGFFGCCGAIQESPCMLGLFFFFLLLIFAVEVAAGIWGFSNQSKVVDDITQFYTQTYSNYKDNKQDALKETLRL---IQHRLNCCGPSNTAEDLKILEDTCPKKDILDDLIIKSCPDAIDEVFNSKLHIIGAVGIGIGVIMIFGMVFSMMLCCAIRKTRE 228          
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: cd81b (CD81 antigen-like [Source:NCBI gene;Acc:111196718])

HSP 1 Score: 63.1586 bits (152), Expect = 1.913e-11
Identity = 63/225 (28.00%), Postives = 107/225 (47.56%), Query Frame = 1
Query:   91 IKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSI-----------DEHFTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKI--SVNTATKD-QIKIMDKIQNELQCCGV--ISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEA 717
            IKY LFFFN I ++ G VI  + ++ R   Q  ++              +   Y+ I +G ++    FLGCYGAI ES CLL  F   +  +F   +AAG+W   +++ I  ++ +       K    V T +K    K++    + L+CCG    + L    +  L C    I     + CH  +++     ++ I   A+ + +IM+  MI +++LCCA++ A
Sbjct:   10 IKYMLFFFNFIFWLAGGVILGIALWLRHDTQTSNLLMLQFEGTQAPGTFYISVYVLIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFINRETISTELISFYDAAYMKAVDPVETPSKQAAAKVLGVFHDTLECCGKGDDNQLFLAVQSSL-CPGRPIDPLVSQSCHMKLRDLFTEKLHVIGLAALIIAVIMVFEMIFTMVLCCAVRNA 233          
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: cd63 (CD63 molecule [Source:NCBI gene;Acc:103032697])

HSP 1 Score: 62.003 bits (149), Expect = 4.859e-11
Identity = 39/161 (24.22%), Postives = 79/161 (49.07%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPP--------------LSCGNDYITISTK---KGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMI--CSIM 693
            C GA  E+ C++ +F++++  I +V +   + A   + K+   + + L +++ +   N  +K+  + +D+IQ +L+CCG  +  D+V   P                CG   +    K    GC  ++++ LK N+  +   AI +  I +LG++  CS+M
Sbjct:   72 CCGAWKENYCMVTMFAILLSLIIIVEIGTAIAAYVFRDKLTGLVDDGLRDMIKQY--NNGSKEYQEGLDRIQKDLKCCGAANSSDWVNFKPDHTSVPDSCCKNVTADCGKGAMNDDKKIYVTGCQPALEKLLKENVQWVAVAAIVIAFIEILGLVFACSLM 230          
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005284.1 (pep scaffold:Pmarinus_7.0:GL480552:16638:25636:-1 gene:ENSPMAG00000004798.1 transcript:ENSPMAT00000005284.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.855 bits (159), Expect = 6.468e-13
Identity = 72/247 (29.15%), Postives = 117/247 (47.37%), Query Frame = 1
Query:   58 ARIRLAASFKFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSI-DEHFTGA-YXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLD------YVEKPP---------------LSCGNDYI------TISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIK 711
            A + L      IKY +  FNL+ ++ G+ +  VG  A++     S+   + +GA Y+ I +G++I + +  GC GA  ES  ++  FS+ +F IFV  +AAG+ A   K ++   +     E   K+ +N         +D +Q ELQCCGV+ + D      +V   P                 CG D I       I   KGC E ++  +K NI  + G+AI +G   L+G+   I+ CC ++
Sbjct:    7 AEMALEGGMACIKYLVLLFNLLFWLSGLGLIIVGAMAQMHIGAFSVVTGNLSGAPYVIIAVGVVIFVVAAFGCCGAHKESYFMVATFSVFLFLIFVAELAAGIGAYIFKDQLRDVV-----ETKAKVVINDYPTKNKDPVDNMQKELQCCGVVHYQDWFNSTNWVTSDPNNPNSVPDSCCLNVTSGCGQDDIRFKNATAIIYTKGCVEKLEATMKENIVLVGGVAIGIGFAQLIGI---ILACCLMR 245          
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: tspan4a (tetraspanin 4a [Source:ZFIN;Acc:ZDB-GENE-040718-38])

HSP 1 Score: 59.3066 bits (142), Expect = 8.258e-11
Identity = 40/169 (23.67%), Postives = 79/169 (46.75%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYV-----EKPP--------LSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKFANH 735
            C GAI E  CLL+ F + +  IFV+ M   +    ++ +ID    + L E + ++  +          + +Q +  CCGV++H D+      ++ P        + CG D        GC++ ++ +++ N+  +    + + +I +LGM  S+ + C +   +K  NH
Sbjct:   67 CLGAIKEHKCLLLSFFVCLLIIFVLEMICVILFFMYRDQIDGHAKDDLKEGL-RLYGSEGNVGLTNAWNIVQTDFHCCGVVNHTDWFLAFGDKRVPDSCCMEYSVDCGRDKPNTWWPSGCYDKVEAWIEENLMVLGVFILCISLIQILGMAFSMSMFCQLYRQKK--NH 232          
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: tspan3a (tetraspanin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-7787])

HSP 1 Score: 58.151 bits (139), Expect = 3.138e-10
Identity = 40/178 (22.47%), Postives = 90/178 (50.56%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKP----------PLSCGNDYITIST----------KKGCHESIKEFLKVNINKIIGLAIFVGIIM--LLGMICSIMLCCAIKEAEKFANH 735
            C   + ES C L  F +++  IF + + A L   A++ ++  K+  ++S++  + +  T +    + +D +Q++L+CCGV ++LD+ ++P          P+SC    +T              +GC   +++ +K  +N ++ +A+   ++   +LG I S+ +C  ++ +  +AN 
Sbjct:   74 CCATVRESKCGLSTFFILLLMIFSLEVVAALLGYAYRGQVKDKVERTISQVFNEYN-GTDSNTASRAIDYVQHQLKCCGVKNYLDWKDRPWFNHTGNNSVPISCCRSNVTHCDGNIKHPGDIYNEGCEAMVEKTVKDILNYVMRVALIYALVQGYILG-IKSVRVCVCVR-STYWANR 248          
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: tspan4a (tetraspanin 4a [Source:ZFIN;Acc:ZDB-GENE-040718-38])

HSP 1 Score: 55.8398 bits (133), Expect = 1.336e-9
Identity = 38/165 (23.03%), Postives = 78/165 (47.27%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYV-------------EKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            C GAI E+PCLL+ F +++  +F+     G+    ++ K++ +  + L + +  +             + + +E+ CCGV +H D+                P   CG+   +   + GC+E +K ++K N+  +    + +  I +LGM+ S+ + C ++  EK
Sbjct:   74 CLGAIKENPCLLLTFFVLLLVVFLAEFVGGVLFFVYQGKLETRAQDDLRQGL-HLYGTEGNVGLTNAWNTLHSEVGCCGVHNHTDWFAVFGERRVPDSCCRDPASGCGSVPSSAYARPGCYEKLKSWIKDNLAYVGIFCLGIATIQILGMVFSMTMFCHLRAEEK 237          
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003691.1 (pep scaffold:Pmarinus_7.0:GL489663:1636:6170:1 gene:ENSPMAG00000003372.1 transcript:ENSPMAT00000003691.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 45.8246 bits (107), Expect = 2.976e-7
Identity = 28/78 (35.90%), Postives = 44/78 (56.41%), Query Frame = 1
Query:  481 QNELQCCGVISHLDYVEK-PPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIK 711
            +++L CCG   +L+Y       SC  +Y      K C + I+ FL   +  + GLA+ V +IM+ GMI S+ +CCAI+
Sbjct:    1 RSQLDCCGQ-PNLNYTSLLSTYSCPPEY-----TKNCVDEIRSFLGTKVYIVAGLALGVAVIMIFGMIFSMAVCCAIR 72          
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO43827 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXD6])

HSP 1 Score: 66.6254 bits (161), Expect = 4.213e-13
Identity = 48/155 (30.97%), Postives = 83/155 (53.55%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKP---PLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            C GA  E+ C++  F++++ FIFV+ +AAG  A A+K K++  +   L   V         K+  K MDK+Q E +CCG     D+  K    P SC +   T+ +K  C + +++FLK ++  + G+ I +  + L+G+   I  CC ++  +K
Sbjct:   71 CCGAYKENYCMVTTFAVLLAFIFVLEIAAGALAYAYKGKLEGYVRTGLKNGVDHYD----KKEYKKAMDKVQGEFKCCGYEDSNDHGYKNSTVPKSCKDTNGTVFSKN-CVKGLEKFLKDHLIVVGGVGIGIAFVQLIGI---IFACCMMRSIKK 217          
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO46887 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNN8])

HSP 1 Score: 66.2402 bits (160), Expect = 7.178e-13
Identity = 43/177 (24.29%), Postives = 86/177 (48.59%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKP---------PLSCGNDY------------ITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKE--AEKFA 729
            C GA+ ES C+L  +  ++  IF + + A + A  ++++I+K +   +   + +  + +      + +D+I  + +CCG   + D+ E           P SC  D              T   ++GC+  +K++L  N++ I G  I++ +I L+G+I +  LCC I+   +E +A
Sbjct:   65 CCGALKESQCMLGTYFGLVTAIFCLEVTAIVLAYVYRERIEKNLHGDIRSTMNEYHL-SGHDAVTRAIDEIHRDFKCCGNAQYRDWFETKWAKTHPDMVPRSCCKDPSDSKCNENISKDPTKIYRRGCYMFVKKYLSNNLHVISGFGIWIAVIQLMGIIFATCLCCHIRTILSEDYA 240          
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO47592 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLE8])

HSP 1 Score: 61.2326 bits (147), Expect = 3.421e-11
Identity = 70/236 (29.66%), Postives = 120/236 (50.85%), Query Frame = 1
Query:   91 IKYALFFFNLXXXXXXXXXXXXXXYARIS-EQYLSID--EHFTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQI-KIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYI-------TIST------------KKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKFA 729
            IKY +F FN I F+ G+ +  VGIY ++    Y+ +   ++ TG+ + I +G  I + SF GC GAI E  CLL  F  ++F I  V +        ++ K+++++G  +++ +  +S     K+ I    D IQ + +CCG+    D+ ++   + GN  I       T+S              KGC +++K  LK N+  I G+ I V +I +L MI +++L C I    ++A
Sbjct:   10 IKYMVFLFNFIFFLGGVGLMGVGIYVQLKIGDYVELQSVKYITGSIIIIAVGAFIALVSFFGCCGAIKEHRCLLATFFALLFIILAVEITGTALGYVYRNKVEEQLGKDMNDTI--VSYGEKGKEGITDAYDAIQKKEKCCGINGFKDW-QRSYYTKGNHSIVPDSCCKTVSKGCGINFKENDIYTKGCFDTVKTLLKDNLIIIGGIGIGVAVIQILAMIFAMVLVCKIGAQSEYA 242          
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO34309 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPQ7])

HSP 1 Score: 61.2326 bits (147), Expect = 3.722e-11
Identity = 40/162 (24.69%), Postives = 74/162 (45.68%), Query Frame = 1
Query:  274 GAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEK---------PPLSCGND------YITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKE 714
            G   ES C L +F +++  +F + + AG+    +K +   ++ N L++ +   S     +   K +DK+Q  L CCG     D+V           P   C +D      Y      KGC+ ++ +    N++ IIG+ I   ++ L+GM+ +  + C+  E
Sbjct:   69 GTCRESKCCLSIFFILLLVVFSLEITAGVLGAIYKNQAKDEVKNGLTDAIDHYS--KEEQGFQKAVDKLQENLDCCGSTGPNDWVNSTFWKEKHHLPKSCCTHDSDVCFPYDKFHNTKGCYTTLLDKFNKNLSYIIGIGIGFAVLQLIGMLSACCVMCSTGE 228          
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO38288 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDC9])

HSP 1 Score: 55.4546 bits (132), Expect = 4.721e-9
Identity = 66/235 (28.09%), Postives = 108/235 (45.96%), Query Frame = 1
Query:   91 IKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEHFTG-----AYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDY-------VEKP-------PLSC--------------------GNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGM 678
            +KY LFFFN+  ++ G ++ SVG+YAR  +   +  E F+      A+  I +G I+ I  F GC GA+ E+ CLL  FS+V+  IF + +A G++    + K++  I   L   V K   N    D   ++D +Q E +CCG     D+          P       P SC                     +D   I    GC  ++K++ K N+  I G A+ + ++ ++G+
Sbjct:   12 VKYLLFFFNVFFWLVGCLLVSVGLYARFEKT--AYQEFFSDILTDPAFALIIVGGIMFILGFSGCIGALRENICLLKFFSVVLAIIFFLQLALGVFVFVFQDKVEAVIVEKLQTAVTKYRDNA---DLQNLIDGVQQEFKCCGAKGINDWDKNIYFNCSSPGSEACGVPYSCCIKDTINRQCGYGIRKSGTPTSDQSKIIFIGGCVNAVKDWFKSNMIIIGGAAVGIALLQIMGI 241          
BLAST of Tetraspanin vs. Ensembl Medaka
Match: ENSORLT00000021688.2 (tetraspanin-8 [Source:NCBI gene;Acc:101157824])

HSP 1 Score: 81.2629 bits (199), Expect = 6.797e-18
Identity = 53/161 (32.92%), Postives = 87/161 (54.04%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKI-MDKIQNELQCCGVISHLDYVEKPPLSC---GNDYITISTKKG------CHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAE 720
            C GA  ES C+L++F + +  IF +L+AAG+     ++ ++  +   L     K++  +   D +K  ++ +Q EL+CCG+I       KPP SC   G D  T +T KG      C + I   +K N+  ++G++  + IIM+LGMI S+M+ C I   E
Sbjct:   84 CLGAYKESRCMLMMFFIFLLVIFTLLLAAGILGAVGEKTVNDWVRKELQ----KLTPLSNQPDSVKKDLEALQAELKCCGIIQGPADWTKPPASCFCNGTD--TTTTCKGGIYQTPCADQIINLMKQNMKVVLGISFAIAIIMILGMIFSMMIYCQIGRKE 238          
BLAST of Tetraspanin vs. Ensembl Medaka
Match: ENSORLT00000000775.2 (CD82 antigen [Source:NCBI gene;Acc:101156312])

HSP 1 Score: 75.485 bits (184), Expect = 1.104e-15
Identity = 49/171 (28.65%), Postives = 83/171 (48.54%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKP----------PLSCGNDYITISTKK-----------------GCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLC 699
            C GAI +  CLL L+   +  I V  +AAG+     K+K+++++   + +++G  + N++  +Q    D IQ ++QCCG +   D+              P SC N  +T+  +                  GC  S++ +L  NI  ++G+ + V +I LLGMI SI LC
Sbjct:   73 CLGAIFQIKCLLGLYFTCLLVILVAQIAAGVLVYLQKEKVNEQMSKIVDKVLGSYAGNSSRTEQA--WDLIQKKMQCCGWMGQEDWNNNAVILNSSQLLFPCSCQNLTLTVQNRSDSGFCEAQTPDWPVYNVGCSASVENWLITNIGVVLGICLTVALIELLGMILSICLC 241          
BLAST of Tetraspanin vs. Ensembl Medaka
Match: cd9a (CD9 antigen [Source:NCBI gene;Acc:101173781])

HSP 1 Score: 74.7146 bits (182), Expect = 1.357e-15
Identity = 65/218 (29.82%), Postives = 118/218 (54.13%), Query Frame = 1
Query:   91 IKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEH-------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEK 723
            +KY +F FNL+ ++ G  + ++G++ R+  Q   + E        + G Y+ I  G +I +  FLGC GAI ESPC+L +F   +  +F + +AAG+W  +++ K+ + I +S      K   +T  +   + +  IQ +L+CCG     D   K     G     +  K  C ++I+E     ++ I  + I +G++M+ GMI S++LCCAI+++++
Sbjct:   11 VKYLMFAFNLVFWLAGTTVLAIGLWLRLDPQNKVLLEEENSPYAFYAGVYVLIGAGALIMVVGFLGCCGAIRESPCMLGVFFFFLLILFAIEVAAGIWGFSNQTKVVEDI-SSFYMQTYKDYTSTGDERVKETLRLIQAQLKCCGPGKDTDESFKETCPRGEPLEELLIKS-CPDAIEEVFDSKLHIIAVVGITMGVVMVFGMIFSMLLCCAIRKSQE 226          
BLAST of Tetraspanin vs. Ensembl Medaka
Match: cd81a (CD81 antigen-like [Source:NCBI gene;Acc:101156484])

HSP 1 Score: 67.3958 bits (163), Expect = 7.269e-13
Identity = 69/235 (29.36%), Postives = 116/235 (49.36%), Query Frame = 1
Query:   91 IKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSI-----------DEHFTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKI---GNSLSEIVGKISVNTATKDQIKIMDKIQ---NELQCCG------VISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKF 726
            IKY LFF N I ++ G VI  + ++ R   Q  S+              +T  ++ I +G ++ +  FLGCYGAI ES CLL  F   +  +F   +AAG+    H++ I K++    +SL +   K S+ T +  ++  M  ++     L+CCG      + S    ++     C  +Y+T+S    CH SI +     I+ +   A+ + IIM+  MI S++LCC I+ +  +
Sbjct:   10 IKYTLFFCNFIFWLAGGVILGLALFLRHDHQVKSLLDITVDGQQPPSTFYTSIHILIAVGAVMMVVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGILGYMHRETISKEMIIFYDSLYDEAMKTSL-TESDRKVAAMQGLKIFHETLKCCGKGLGTSLFSKFVGMKDGVDVCSTEYVTVS----CHTSINDLFSTKIHIVGIAALVIAIIMIFEMIFSMVLCCGIRNSPVY 239          
BLAST of Tetraspanin vs. Ensembl Medaka
Match: cd81b (CD81 antigen [Source:NCBI gene;Acc:101175317])

HSP 1 Score: 66.2402 bits (160), Expect = 1.574e-12
Identity = 67/233 (28.76%), Postives = 104/233 (44.64%), Query Frame = 1
Query:   64 IRLAASFKFIKYALFFFNLXXXXXXXXXXXXXXYARISEQY-----LSIDEH------FTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGK---ISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAE 720
            + +A   K IKY LFFFN I ++ G VI  + ++ R   Q      L  D        +   Y+ I +G ++ +  FLGCYGAI ES CLL  F   +  +F   +AA LW   +K  I K++ N       K   +S  T+     K++D     L CCG  +     +    S        +  + CH  +       +  I   A+ V +IM+  MI +++LCC I+ + 
Sbjct:    1 MAVAGCTKCIKYMLFFFNFIFWLAGGVILGMALWLRHDSQTSKLLILQFDGQQAPSTFYISVYILIAVGAVMMLVGFLGCYGAIQESQCLLGTFFFFLVILFACEVAAALWGFMNKDTISKELINFYDAAYIKAVDVSDPTSKDSATKVLDVFHTALDCCGKGNDTALFKHVAASLCPGKTLQNPSQSCHTKLTWLFSEKLYLIGLAALAVAVIMVFEMIFTMVLCCGIRNSP 233          
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000008659.1 (SMESG000008659.1)

HSP 1 Score: 387.111 bits (993), Expect = 2.041e-137
Identity = 226/227 (99.56%), Postives = 227/227 (100.00%), Query Frame = 1
Query:   55 MARIRLAASFKFIKYALFFFNLXXXXXXXXXXXXXXYARISEQYLSIDEHFTGAYXXXXXXXXXXXXXXXXCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKFANH 735
            MARIRLAASFKFIKYALFFFNLISFIFGIVIFSVGIYARISEQYLSIDEHFTGAYLFIFIGLIITITSFLGCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISH+DYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKFANH
Sbjct:    1 MARIRLAASFKFIKYALFFFNLISFIFGIVIFSVGIYARISEQYLSIDEHFTGAYLFIFIGLIITITSFLGCYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHIDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAEKFANH 227          
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000043678.1 (SMESG000043678.1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.862e-15
Identity = 42/151 (27.81%), Postives = 70/151 (46.36%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAE 720
            C GA  ESPCLL  + + +  IF   +AAG+  + +K K+   +G    +  G   + +   D    M+ +Q  ++CCG     DY + P   C          +GC  +  E ++ N      + + + +I LLG+I S+ LCC  +  E
Sbjct:   72 CCGAYHESPCLLGTYFIFLLLIFAAEIAAGVLVVLYKDKVKSYVGVKFQK--GTEELKSKPDDTEHWMNGVQRNMKCCGYKGSSDYTKVPGSCCSTSKCEDPYTRGCESAWTELIQNNWVIFASILLGIPLIELLGLIFSMCLCCTARSIE 220          
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000021627.1 (SMESG000021627.1)

HSP 1 Score: 63.1586 bits (152), Expect = 1.829e-11
Identity = 50/164 (30.49%), Postives = 79/164 (48.17%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLD------YVEKP------PLSCGND----YITIST----KKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLC 699
            C GA+ ES  LL ++ + +  I  + +A G++AI +KQKI+K +  +L   + ++      KD  KI D IQ  L CCG+    D      Y+EK       P SC  D    Y  IS      +GC   ++E+L+      IG+ + +    +  +IC+  LC
Sbjct:   74 CCGAVRESKLLLGMYIVFLMLIIFIQVALGIFAIFYKQKIEKSVSKTLKTAITELY--GYDKDNDKITDNIQQILSCCGIEGPQDWEKSKWYIEKMNKSQMFPKSCCRDNAECYNKISGATAFSEGCVSRLREYLQRIFPIFIGVILGIAFFEIFVVICAFCLC 235          
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000035080.1 (SMESG000035080.1)

HSP 1 Score: 62.3882 bits (150), Expect = 3.029e-11
Identity = 51/166 (30.72%), Postives = 80/166 (48.19%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKP-----PLSCGNDYITISTK----------KGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKEAE 720
            C+GA  ES  +L ++  V+ F+F   +A G     +K   D+K+  +L   +     +  TK +   ++ +Q  L+CCGV S  DY++K      P SC  DY     K          KGC +  KEF +  +  I  + I +  I  LGMI S+ LC +I+ A+
Sbjct:   75 CFGAYHESQPILGIYFSVMLFLFASQVAVGSLYFVYK---DEKLTTNLKISIQNYMNSKITKQEEIFLNSVQKMLKCCGVDSVNDYIKKDTPSNIPFSCC-DYEIHECKAKVEKKNAFTKGCKDKYKEFSQHKLGVISMIIIVMCTIEFLGMIFSVALCFSIRYAD 236          
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000063435.1 (SMESG000063435.1)

HSP 1 Score: 56.6102 bits (135), Expect = 2.647e-9
Identity = 42/155 (27.10%), Postives = 76/155 (49.03%), Query Frame = 1
Query:  268 CYGAISESPCLLILFSMVIFFIFVVLMAAGLWAIAHKQKIDKKIGNSLSEIVG--KISVNTATKDQIKIMDKIQNELQCCGVISHLDYVEKPPLSC--GNDYITIST--KKGCHESIKEFLKVNINKIIGLAIFVGIIMLLGMICSIMLCCAIKE 714
            C GAI ES  +LI+F + +  + +  +A  +    ++  +   IG  +++ V   K + +TA +    ++D  Q   QCCGV S  D+ +  P SC   N      T  K  C  ++   ++  I  + G+A+ V ++ ++GMI +  L  +I E
Sbjct:   70 CCGAIQESKVMLIIFGVCLIVLLIAQIALSIAVYVYRSNVSTIIGKQMNDAVNIYKTTNDTAAR---ALVDSTQQLFQCCGVNSTSDWGKTVPNSCCQNNTVCNADTAFKTNCINAMVSKVQSQIGILAGVALLVCLVEIIGMILAFFLSKSIAE 221          
The following BLAST results are available for this feature:
BLAST of Tetraspanin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CD812.046e-1530.00CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701][more]
CD99.179e-1531.08CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709][more]
CD99.179e-1531.08CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709][more]
CD99.179e-1531.08CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709][more]
CD811.588e-1429.11CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701][more]
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BLAST of Tetraspanin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
tsp-97.455e-626.17Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q18177][more]
tsp-97.455e-626.17Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q18177][more]
tsp-69.206e-627.22Tetraspanin [Source:UniProtKB/TrEMBL;Acc:G4RWX0][more]
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BLAST of Tetraspanin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tsp47F5.181e-1235.65gene:FBgn0033629 transcript:FBtr0088151[more]
Tsp74F2.202e-1025.76gene:FBgn0036769 transcript:FBtr0075155[more]
Tsp74F2.202e-1025.76gene:FBgn0036769 transcript:FBtr0075154[more]
Tsp29Fa2.176e-923.39gene:FBgn0032074 transcript:FBtr0300289[more]
Tsp29Fa2.176e-923.39gene:FBgn0032074 transcript:FBtr0340261[more]
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BLAST of Tetraspanin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cd9a3.480e-1832.88CD9 molecule a [Source:ZFIN;Acc:ZDB-GENE-030131-11... [more]
cd9a6.542e-1832.59CD9 molecule a [Source:ZFIN;Acc:ZDB-GENE-030131-11... [more]
tspan4b1.715e-1629.01tetraspanin 4b [Source:ZFIN;Acc:ZDB-GENE-070410-12... [more]
tspan4b1.821e-1629.01tetraspanin 4b [Source:ZFIN;Acc:ZDB-GENE-070410-12... [more]
cd81a1.798e-1432.16CD81 molecule a [Source:ZFIN;Acc:ZDB-GENE-000831-5... [more]
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BLAST of Tetraspanin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cd91.467e-1630.18CD9 protein [Source:NCBI gene;Acc:549743][more]
tns13.795e-1231.58tensin 1 [Source:Xenbase;Acc:XB-GENE-957068][more]
trip45.760e-1228.05thyroid hormone receptor interactor 4 [Source:Xenb... [more]
trip48.432e-1228.05thyroid hormone receptor interactor 4 [Source:Xenb... [more]
ENSXETT00000022335.13.674e-1023.08tetraspanin-4-like [Source:NCBI gene;Acc:101734690... [more]
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BLAST of Tetraspanin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cd96.202e-1831.22CD9 antigen [Source:MGI Symbol;Acc:MGI:88348][more]
Cd811.600e-1527.95CD81 antigen [Source:MGI Symbol;Acc:MGI:1096398][more]
Cd824.058e-1326.11CD82 antigen [Source:MGI Symbol;Acc:MGI:104651][more]
Cd824.058e-1326.11CD82 antigen [Source:MGI Symbol;Acc:MGI:104651][more]
Cd824.058e-1326.11CD82 antigen [Source:MGI Symbol;Acc:MGI:104651][more]
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BLAST of Tetraspanin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P30932|CD9_BOVIN3.764e-1731.34CD9 antigen OS=Bos taurus OX=9913 GN=CD9 PE=2 SV=2[more]
sp|P40240|CD9_MOUSE4.338e-1731.22CD9 antigen OS=Mus musculus OX=10090 GN=Cd9 PE=1 S... [more]
sp|O97703|CD81_CHLAE1.086e-1530.87CD81 antigen OS=Chlorocebus aethiops OX=9534 GN=CD... [more]
sp|P40241|CD9_RAT1.475e-1530.32CD9 antigen OS=Rattus norvegicus OX=10116 GN=Cd9 P... [more]
sp|Q8WMQ3|CD9_PIG3.870e-1530.91CD9 antigen OS=Sus scrofa OX=9823 GN=CD9 PE=2 SV=3[more]
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BLAST of Tetraspanin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
I3NQF95.143e-3840.89Tetraspanin OS=Spirometra erinaceieuropaei OX=9980... [more]
A0A0X3Q4N95.920e-3540.00Tetraspanin OS=Schistocephalus solidus OX=70667 GN... [more]
A0A504YFQ91.202e-3042.22Tetraspanin OS=Fasciola gigantica OX=46835 GN=FGIG... [more]
U6JEW11.248e-3038.67Tetraspanin OS=Echinococcus granulosus OX=6210 GN=... [more]
A0A5K3F6K11.560e-3038.67Uncharacterized protein OS=Mesocestoides corti OX=... [more]
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BLAST of Tetraspanin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cd81a1.580e-1533.04CD81 molecule [Source:NCBI gene;Acc:103037709][more]
cd9a1.673e-1229.82CD9 antigen-like [Source:NCBI gene;Acc:103028636][more]
cd9a1.010e-1130.32CD9 antigen-like [Source:NCBI gene;Acc:103028636][more]
cd81b1.913e-1128.00CD81 antigen-like [Source:NCBI gene;Acc:111196718][more]
cd634.859e-1124.22CD63 molecule [Source:NCBI gene;Acc:103032697][more]
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BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000005284.16.468e-1329.15pep scaffold:Pmarinus_7.0:GL480552:16638:25636:-1 ... [more]
tspan4a8.258e-1123.67tetraspanin 4a [Source:ZFIN;Acc:ZDB-GENE-040718-38... [more]
tspan3a3.138e-1022.47tetraspanin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-77... [more]
tspan4a1.336e-923.03tetraspanin 4a [Source:ZFIN;Acc:ZDB-GENE-040718-38... [more]
ENSPMAT00000003691.12.976e-735.90pep scaffold:Pmarinus_7.0:GL489663:1636:6170:1 gen... [more]
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BLAST of Tetraspanin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Tetraspanin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO438274.213e-1330.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO468877.178e-1324.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO475923.421e-1129.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO343093.722e-1124.69Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO382884.721e-928.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Tetraspanin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000021688.26.797e-1832.92tetraspanin-8 [Source:NCBI gene;Acc:101157824][more]
ENSORLT00000000775.21.104e-1528.65CD82 antigen [Source:NCBI gene;Acc:101156312][more]
cd9a1.357e-1529.82CD9 antigen [Source:NCBI gene;Acc:101173781][more]
cd81a7.269e-1329.36CD81 antigen-like [Source:NCBI gene;Acc:101156484][more]
cd81b1.574e-1228.76CD81 antigen [Source:NCBI gene;Acc:101175317][more]
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BLAST of Tetraspanin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000008659.12.041e-13799.56SMESG000008659.1[more]
SMESG000043678.11.862e-1527.81SMESG000043678.1[more]
SMESG000021627.11.829e-1130.49SMESG000021627.1[more]
SMESG000035080.13.029e-1130.72SMESG000035080.1[more]
SMESG000063435.12.647e-927.10SMESG000063435.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004488 ID=SMED30004488|Name=Tetraspanin|organism=Schmidtea mediterranea sexual|type=transcript|length=846bp
GAAAAATTTAATAGTTATTTTAGATTTCTATAATTGGAAATTATTTTTTC
CTAAATGGCCCGGATCAGATTAGCAGCCTCTTTTAAATTTATTAAATATG
CGTTGTTCTTTTTTAATTTGATATCCTTTATATTTGGAATCGTAATCTTT
TCCGTCGGTATCTATGCAAGAATCTCTGAGCAATATCTTTCGATAGATGA
ACATTTTACCGGAGCGTATCTTTTTATTTTTATTGGACTCATAATTACGA
TAACTTCGTTTCTTGGATGTTATGGAGCCATTTCAGAAAGTCCTTGTTTG
CTAATTTTGTTTTCTATGGTTATATTTTTTATCTTTGTTGTTTTAATGGC
TGCAGGATTGTGGGCCATTGCACACAAACAAAAGATAGACAAAAAAATTG
GGAATTCACTATCTGAAATTGTAGGTAAAATCTCAGTCAATACCGCAACC
AAAGACCAGATTAAGATAATGGACAAGATACAAAATGAACTCCAATGTTG
CGGAGTAATTTCGCATCTAGATTATGTAGAGAAGCCTCCATTGTCCTGTG
GAAACGATTATATAACTATATCCACAAAAAAAGGATGTCATGAAAGTATC
AAAGAATTTCTAAAAGTGAATATTAATAAAATAATCGGGTTAGCAATTTT
TGTTGGGATAATAATGTTATTGGGGATGATTTGTTCTATAATGCTCTGTT
GCGCTATTAAGGAAGCGGAAAAATTTGCAAATCATTAGCAATATAAAAAA
TAAATTATCTGAAAAAACTATTTGTATTTTTAGAAAATAATATTAAATTA
TATATTGATTGAGATTGTTAAAATAATAAATTTTCCATAAAAAAAA
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protein sequence of SMED30004488-orf-1

>SMED30004488-orf-1 ID=SMED30004488-orf-1|Name=SMED30004488-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=228bp
MARIRLAASFKFIKYALFFFNLISFIFGIVIFSVGIYARISEQYLSIDEH
FTGAYLFIFIGLIITITSFLGCYGAISESPCLLILFSMVIFFIFVVLMAA
GLWAIAHKQKIDKKIGNSLSEIVGKISVNTATKDQIKIMDKIQNELQCCG
VISHLDYVEKPPLSCGNDYITISTKKGCHESIKEFLKVNINKIIGLAIFV
GIIMLLGMICSIMLCCAIKEAEKFANH*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR000301Tetraspanin
IPR018499Tetraspanin/Peripherin
IPR028977CD81_LEL
IPR008952Tetraspanin_EC2_sf
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000301TetraspaninPRINTSPR00259TMFOURcoord: 192..218
score: 32.15
coord: 50..76
score: 33.49
coord: 15..38
score: 33.87
coord: 77..105
score: 28.32
IPR000301TetraspaninPIRSFPIRSF002419Tetraspanincoord: 5..227
e-value: 3.3E-44
score: 148.5
IPR018499Tetraspanin/PeripherinPFAMPF00335Tetraspanincoord: 13..217
e-value: 9.0E-44
score: 149.9
IPR008952Tetraspanin, EC2 domain superfamilyGENE3DG3DSA:1.10.1450.10coord: 105..189
e-value: 5.4E-15
score: 57.0
IPR008952Tetraspanin, EC2 domain superfamilySUPERFAMILYSSF48652Tetraspanincoord: 107..188
NoneNo IPR availablePANTHERPTHR19282TETRASPANINcoord: 8..221
NoneNo IPR availablePANTHERPTHR19282:SF39LEUKOCYTE SURFACE ANTIGEN CD53coord: 8..221
NoneNo IPR availableCDDcd03127tetraspanin_LELcoord: 105..190
e-value: 9.29884E-13
score: 60.2107
NoneNo IPR availableTMHMMTMhelixcoord: 83..105
NoneNo IPR availableTMHMMTMhelixcoord: 17..39
NoneNo IPR availableTMHMMTMhelixcoord: 54..76
NoneNo IPR availableTMHMMTMhelixcoord: 193..215