Lateral signaling target protein 2 homolog

Overview
NameLateral signaling target protein 2 homolog
Smed IDSMED30004461
Length (bp)2093
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Lateral signaling target protein 2 homolog (SMED30004461) t-SNE clustered cells

Violin plots show distribution of expression levels for Lateral signaling target protein 2 homolog (SMED30004461) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Lateral signaling target protein 2 homolog (SMED30004461) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Lateral signaling target protein 2 homolog (SMED30004461) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30004461

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30004461SMESG000080555.1 SMESG000049002.1 SMESG000075946.1 SMESG000067287.1 SMESG000064983.1 SMESG000064843.1 SMESG000062987.1 SMESG000047155.1 SMESG000013953.1 Contig927GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30004461SMESG000080555.1 SMESG000049002.1 SMESG000075946.1 SMESG000067287.1 SMESG000064983.1 SMESG000064843.1 SMESG000062987.1 SMESG000047155.1 SMESG000013953.1 Contig927GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30004461SMESG000076100.1 Contig927GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30004461SMESG000076100.1 Contig927GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
epidermisSMED30004461SMESG000076100.1 dd_Smed_v4_5416_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Human
Match: ZFYVE21 (zinc finger FYVE-type containing 21 [Source:HGNC Symbol;Acc:HGNC:20760])

HSP 1 Score: 60.4622 bits (145), Expect = 1.424e-9
Identity = 28/70 (40.00%), Postives = 33/70 (47.14%), Query Frame = 1 
Query: 1648 LDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
              S F L  PQW  D    +C  CD  F+   R+HHCRRCG  FC  C   K+ L  +     V  C EC
Sbjct:   30 FGSPFGLEEPQWVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCAEC 99
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Human
Match: ZFYVE21 (zinc finger FYVE-type containing 21 [Source:HGNC Symbol;Acc:HGNC:20760])

HSP 1 Score: 60.8474 bits (146), Expect = 1.488e-9
Identity = 28/70 (40.00%), Postives = 33/70 (47.14%), Query Frame = 1 
Query: 1648 LDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
              S F L  PQW  D    +C  CD  F+   R+HHCRRCG  FC  C   K+ L  +     V  C EC
Sbjct:   30 FGSPFGLEEPQWVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCAEC 99
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Human
Match: RUFY1 (RUN and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19760])

HSP 1 Score: 59.6918 bits (143), Expect = 1.580e-8
Identity = 25/63 (39.68%), Postives = 35/63 (55.56%), Query Frame = 1 
Query: 1681 WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFL 1869
            W  D     C  C++ F+I RR+HHCR CG++FC++C   +L LP+     RV  C  C   L
Sbjct:  531 WLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRV--CDSCHTLL 591
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Human
Match: RUFY1 (RUN and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19760])

HSP 1 Score: 59.6918 bits (143), Expect = 1.580e-8
Identity = 25/63 (39.68%), Postives = 35/63 (55.56%), Query Frame = 1 
Query: 1681 WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFL 1869
            W  D     C  C++ F+I RR+HHCR CG++FC++C   +L LP+     RV  C  C   L
Sbjct:  531 WLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRV--CDSCHTLL 591
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Human
Match: RUFY1 (RUN and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19760])

HSP 1 Score: 59.6918 bits (143), Expect = 1.580e-8
Identity = 25/63 (39.68%), Postives = 35/63 (55.56%), Query Frame = 1 
Query: 1681 WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFL 1869
            W  D     C  C++ F+I RR+HHCR CG++FC++C   +L LP+     RV  C  C   L
Sbjct:  531 WLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRV--CDSCHTLL 591
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Celegans
Match: hgrs-1 (Hepatocyte Growth factor-Regulated TK Substrate (HRS) family [Source:UniProtKB/TrEMBL;Acc:Q17796])

HSP 1 Score: 65.4698 bits (158), Expect = 9.932e-11
Identity = 26/63 (41.27%), Postives = 35/63 (55.56%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEE 1863
            P+W   +  P+C  C   F++F R+HHCR CG +FC  C   +L LP  GI   V +C  C E
Sbjct:  155 PEW---ADGPECYRCRSVFSVFTRKHHCRACGQIFCDKCSSRELALPQFGIEKEVRVCETCYE 214
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Celegans
Match: hgrs-1 (Hepatocyte Growth factor-Regulated TK Substrate (HRS) family [Source:UniProtKB/TrEMBL;Acc:Q17796])

HSP 1 Score: 65.4698 bits (158), Expect = 9.932e-11
Identity = 26/63 (41.27%), Postives = 35/63 (55.56%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEE 1863
            P+W   +  P+C  C   F++F R+HHCR CG +FC  C   +L LP  GI   V +C  C E
Sbjct:  155 PEW---ADGPECYRCRSVFSVFTRKHHCRACGQIFCDKCSSRELALPQFGIEKEVRVCETCYE 214
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Celegans
Match: lst-2 (Lateral signaling target protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q9TZD0])

HSP 1 Score: 63.1586 bits (152), Expect = 4.899e-10
Identity = 72/279 (25.81%), Postives = 124/279 (44.44%), Query Frame = 1 
Query:  745 LLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHXXXXXXXXXXXNALNIQEIHYLCKIL-MNHNEIPQVSTSIMNQSKF--------KAVDDQNIISGDMHALFKLI---------SSVSDRMQSKHASDYRFFMETIFKLYKDEEDANSIQS-VNNSNSFTTSDLFLSQYKNV---MSKYTNIDEAVDALSYSLAEQFPDD 1515
            LL FD  FAEFE ++V  +    + S+   +  LDVAV+FSE +  A   +L+    I  CD  +M+ IPR+ +++G  + + G     ALN    +   E L+ +F+     L ++R  L  L   E+  L  +L    + +P+ ++S +  S F        KA ++Q +   DM +              S  +    S  AS +    E + ++  +E D  +I +  N+SN  T S   + +  NV    S  + +D  +D       ++  DD
Sbjct:  162 LLKFDKLFAEFEYQYVSAMVP--VKSVKEHDSQLDVAVLFSEVLSLALVKDLITQDLIDYCDPSVMIAIPRLGIVWGLLVYSNG-----ALNV---DVPAENLSEMFRPFYSLLVKIRNLLRILTPTELTKLETVLCKGESAVPEDTSSTLTMSDFRTNATDEEKAKNNQRVWMCDMPSDSTSSLDSSVQDSSSETTSLASSALASPHSGSEENVSQIENEEGDDEAIGTNSNSSNEVTESPETIEEPDNVDMEESSESEVDTHIDETRNESDDEITDD 430

HSP 2 Score: 60.077 bits (144), Expect = 4.072e-9
Identity = 23/60 (38.33%), Postives = 31/60 (51.67%), Query Frame = 1 
Query: 1678 QWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +W  D    +C  C   FN  RRRHHCR CG +FC  C    +++P  G   +V +C  C
Sbjct:  562 RWVPDEDCEQCTACSMPFNFVRRRHHCRNCGRIFCHKCSCNTISIPEHGYDRKVRVCNLC 621
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Celegans
Match: ppk-3 (PIP Kinase [Source:UniProtKB/TrEMBL;Acc:G5ED98])

HSP 1 Score: 58.151 bits (139), Expect = 1.995e-8
Identity = 26/69 (37.68%), Postives = 36/69 (52.17%), Query Frame = 1 
Query: 1651 DSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            DS+F   +  W  DS   +C  C+  F  FRRRHHCR CG +FC+ C  + +    LG    + +C  C
Sbjct:  100 DSNF---KQYWMPDSTGRECYQCEERFTTFRRRHHCRLCGQIFCAKCCSSHIDGAALGYMGELRLCDYC 165
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Celegans
Match: aka-1 (A Kinase Anchor protein [Source:UniProtKB/TrEMBL;Acc:H2KZI9])

HSP 1 Score: 56.9954 bits (136), Expect = 5.431e-8
Identity = 30/79 (37.97%), Postives = 36/79 (45.57%), Query Frame = 1 
Query: 1651 DSSFQLSR--PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTR----VSICVECEEFL 1869
            +S  QL +  P W  DS  P C  C+  F I  RRHHCR CG + C SC   K  L  L    +    V +C  C   L
Sbjct:  526 ESELQLGKTSPYWIPDSECPNCMLCNTRFTIITRRHHCRACGRVLCGSCCNEKAFLEYLQEEGKKLQAVRVCKPCSAML 604
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Fly
Match: CG6051 (gene:FBgn0039492 transcript:FBtr0305050)

HSP 1 Score: 75.485 bits (184), Expect = 1.250e-13
Identity = 29/68 (42.65%), Postives = 35/68 (51.47%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +S  LS P W  D   P+C  C   F  FRRRHHCR CG +FC  C      LP  G+   V +C +C
Sbjct:  897 TSATLSPPAWIPDGKAPRCMACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDC 964

HSP 2 Score: 60.4622 bits (145), Expect = 4.691e-9
Identity = 51/159 (32.08%), Postives = 86/159 (54.09%), Query Frame = 1 
Query:  727 KELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHXXXXXXXXXXXNALNIQEIHYLCKILMNHNEI----PQVSTSI 1191
            ++L + L  FD  FAEFEL +V  + +  + S H  E+   + V+FSET+  A  + LL+   +   D G+M  IPR+ ++ G  +  +GPL+   ++   D+     L+ +F+  R  L ++R  L  LN QE++ L K+L  + +I    P  S+SI
Sbjct:  166 EQLYESLKIFDRLFAEFELSYVSAMVQ--VKSRHEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLN---MDMPGDQ-----LSEMFRPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDINTKVPLGSSSI 314
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Fly
Match: CG6051 (gene:FBgn0039492 transcript:FBtr0113297)

HSP 1 Score: 75.485 bits (184), Expect = 1.250e-13
Identity = 29/68 (42.65%), Postives = 35/68 (51.47%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +S  LS P W  D   P+C  C   F  FRRRHHCR CG +FC  C      LP  G+   V +C +C
Sbjct:  897 TSATLSPPAWIPDGKAPRCMACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDC 964

HSP 2 Score: 60.4622 bits (145), Expect = 4.691e-9
Identity = 51/159 (32.08%), Postives = 86/159 (54.09%), Query Frame = 1 
Query:  727 KELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHXXXXXXXXXXXNALNIQEIHYLCKILMNHNEI----PQVSTSI 1191
            ++L + L  FD  FAEFEL +V  + +  + S H  E+   + V+FSET+  A  + LL+   +   D G+M  IPR+ ++ G  +  +GPL+   ++   D+     L+ +F+  R  L ++R  L  LN QE++ L K+L  + +I    P  S+SI
Sbjct:  166 EQLYESLKIFDRLFAEFELSYVSAMVQ--VKSRHEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLN---MDMPGDQ-----LSEMFRPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDINTKVPLGSSSI 314
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Fly
Match: CG6051 (gene:FBgn0039492 transcript:FBtr0339264)

HSP 1 Score: 75.0998 bits (183), Expect = 1.271e-13
Identity = 29/68 (42.65%), Postives = 35/68 (51.47%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +S  LS P W  D   P+C  C   F  FRRRHHCR CG +FC  C      LP  G+   V +C +C
Sbjct:  896 TSATLSPPAWIPDGKAPRCMACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDC 963

HSP 2 Score: 60.4622 bits (145), Expect = 4.532e-9
Identity = 51/159 (32.08%), Postives = 86/159 (54.09%), Query Frame = 1 
Query:  727 KELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHXXXXXXXXXXXNALNIQEIHYLCKILMNHNEI----PQVSTSI 1191
            ++L + L  FD  FAEFEL +V  + +  + S H  E+   + V+FSET+  A  + LL+   +   D G+M  IPR+ ++ G  +  +GPL+   ++   D+     L+ +F+  R  L ++R  L  LN QE++ L K+L  + +I    P  S+SI
Sbjct:  166 EQLYESLKIFDRLFAEFELSYVSAMVQ--VKSRHEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLN---MDMPGDQ-----LSEMFRPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDINTKVPLGSSSI 314
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Fly
Match: CG31064 (gene:FBgn0051064 transcript:FBtr0339249)

HSP 1 Score: 60.8474 bits (146), Expect = 3.394e-9
Identity = 26/63 (41.27%), Postives = 35/63 (55.56%), Query Frame = 1 
Query: 1681 WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTR----VSICVEC 1857
            W  DS    C  C+R FN+ RR+HHCR CG +FC +C  ++ TLP L    +    V +C  C
Sbjct:  813 WAPDSIATHCTACEREFNLTRRKHHCRSCGEIFCKAC--SEHTLPLLNAQGQPGKPVRVCDNC 873
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Fly
Match: CG31064 (gene:FBgn0051064 transcript:FBtr0085125)

HSP 1 Score: 60.077 bits (144), Expect = 5.205e-9
Identity = 26/63 (41.27%), Postives = 35/63 (55.56%), Query Frame = 1 
Query: 1681 WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTR----VSICVEC 1857
            W  DS    C  C+R FN+ RR+HHCR CG +FC +C  ++ TLP L    +    V +C  C
Sbjct:  665 WAPDSIATHCTACEREFNLTRRKHHCRSCGEIFCKAC--SEHTLPLLNAQGQPGKPVRVCDNC 725
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Zebrafish
Match: zfyve21 (zinc finger, FYVE domain containing 21 [Source:ZFIN;Acc:ZDB-GENE-030131-1296])

HSP 1 Score: 70.4774 bits (171), Expect = 4.175e-13
Identity = 30/70 (42.86%), Postives = 36/70 (51.43%), Query Frame = 1 
Query: 1648 LDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
             +S F L  PQW  D   P+C  CD  F+   R+HHCRRCG  FC  C   K+ LP +     V  C EC
Sbjct:   26 FNSPFTLDEPQWVPDKECPRCMQCDTKFDFITRKHHCRRCGRCFCDKCCSQKVALPRMCFVDPVRQCAEC 95
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Zebrafish
Match: zfyve21 (zinc finger, FYVE domain containing 21 [Source:ZFIN;Acc:ZDB-GENE-030131-1296])

HSP 1 Score: 70.0922 bits (170), Expect = 4.226e-13
Identity = 30/70 (42.86%), Postives = 36/70 (51.43%), Query Frame = 1 
Query: 1648 LDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
             +S F L  PQW  D   P+C  CD  F+   R+HHCRRCG  FC  C   K+ LP +     V  C EC
Sbjct:   26 FNSPFTLDEPQWVPDKECPRCMQCDTKFDFITRKHHCRRCGRCFCDKCCSQKVALPRMCFVDPVRQCAEC 95
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Zebrafish
Match: zfyve28 (zinc finger, FYVE domain containing 28 [Source:NCBI gene;Acc:777615])

HSP 1 Score: 60.4622 bits (145), Expect = 7.170e-9
Identity = 25/64 (39.06%), Postives = 30/64 (46.88%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEF 1866
            P+W  D     C  C   F + RR+HHCR CG +FCS C      LP  G    V +C  C  F
Sbjct:  900 PEWVPDEACNSCIACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQMKPVRVCTHCYMF 963
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Zebrafish
Match: hgs (hepatocyte growth factor-regulated tyrosine kinase substrate [Source:ZFIN;Acc:ZDB-GENE-030131-6107])

HSP 1 Score: 60.077 bits (144), Expect = 7.730e-9
Identity = 29/77 (37.66%), Postives = 37/77 (48.05%), Query Frame = 1 
Query: 1651 DSSFQLSR-PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFLRGK 1878
            D+ F   R P W  D+   +C  C   F +  R+HHCR CG +FC  C     T+P  GI   V +C  C E L  K
Sbjct:  149 DAMFAAERAPDW-VDAE--ECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCFEILNKK 222
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Zebrafish
Match: zfyve9b (zinc finger, FYVE domain containing 9b [Source:ZFIN;Acc:ZDB-GENE-110825-2])

HSP 1 Score: 59.6918 bits (143), Expect = 1.071e-8
Identity = 29/72 (40.28%), Postives = 35/72 (48.61%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFL 1869
            SS   + PQW  DS  P C  C   F+  +RRHHCR CG +FC  C   +  L  LG      +CV C   L
Sbjct:  125 SSLGTTAPQWVPDSQAPACMKCGSKFSFTKRRHHCRACGKVFCVVCCDLRYKLTHLG-GKEGRVCVTCHSTL 195
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Xenopus
Match: zfyve21 (Xenopus tropicalis zinc finger FYVE-type containing 21 (zfyve21), transcript variant 2, mRNA. [Source:RefSeq mRNA;Acc:NM_001017344])

HSP 1 Score: 70.0922 bits (170), Expect = 1.107e-12
Identity = 31/68 (45.59%), Postives = 36/68 (52.94%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            S F L  PQW  D   P+C HCD  F+   R+HHCRRCG  FC  C   K+ LP +     V  C EC
Sbjct:   28 SPFCLEEPQWVPDKECPRCMHCDAKFDFITRKHHCRRCGKCFCDKCCSKKVPLPRMCFVDPVRQCGEC 95
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Xenopus
Match: zfyve21 (Xenopus tropicalis zinc finger FYVE-type containing 21 (zfyve21), transcript variant 2, mRNA. [Source:RefSeq mRNA;Acc:NM_001017344])

HSP 1 Score: 69.707 bits (169), Expect = 1.113e-12
Identity = 31/68 (45.59%), Postives = 36/68 (52.94%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            S F L  PQW  D   P+C HCD  F+   R+HHCRRCG  FC  C   K+ LP +     V  C EC
Sbjct:   28 SPFCLEEPQWVPDKECPRCMHCDAKFDFITRKHHCRRCGKCFCDKCCSKKVPLPRMCFVDPVRQCGEC 95
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Xenopus
Match: zfyve21 (Xenopus tropicalis zinc finger FYVE-type containing 21 (zfyve21), transcript variant 2, mRNA. [Source:RefSeq mRNA;Acc:NM_001017344])

HSP 1 Score: 69.707 bits (169), Expect = 1.493e-12
Identity = 31/68 (45.59%), Postives = 36/68 (52.94%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            S F L  PQW  D   P+C HCD  F+   R+HHCRRCG  FC  C   K+ LP +     V  C EC
Sbjct:   33 SPFCLEEPQWVPDKECPRCMHCDAKFDFITRKHHCRRCGKCFCDKCCSKKVPLPRMCFVDPVRQCGEC 100
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Xenopus
Match: rita1 (RBPJ interacting and tubulin associated 1 [Source:Xenbase;Acc:XB-GENE-6462302])

HSP 1 Score: 61.2326 bits (147), Expect = 4.111e-9
Identity = 27/61 (44.26%), Postives = 33/61 (54.10%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            P+W  D+   +C  C  SF + RRRHHCR CG +FCS C     TLP L     V +C  C
Sbjct:  500 PEWLPDNASSQCMSCYASFTLLRRRHHCRSCGKIFCSRCSAYSSTLPYLVSTHPVRVCSHC 560
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Xenopus
Match: rps18 (ribosomal protein S18 [Source:Xenbase;Acc:XB-GENE-488842])

HSP 1 Score: 61.6178 bits (148), Expect = 4.130e-9
Identity = 27/62 (43.55%), Postives = 33/62 (53.23%), Query Frame = 1 
Query: 1672 RPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +P W  DS  P C +C   F   +RRHHCR CG +FC+ C   K  LP +    RV  CV C
Sbjct:  653 QPTWIPDSEAPTCMNCSVKFTFTKRRHHCRACGKVFCAVCCSQKWKLPYMDKEARV--CVVC 712
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Mouse
Match: Zfyve21 (zinc finger, FYVE domain containing 21 [Source:MGI Symbol;Acc:MGI:1915770])

HSP 1 Score: 62.7734 bits (151), Expect = 1.803e-10
Identity = 28/68 (41.18%), Postives = 34/68 (50.00%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            S F L  PQW  D   P+C  CD  F+   R+HHCRRCG  FC  C   K+ L  +     V  C +C
Sbjct:   32 SPFGLEEPQWVPDKECPRCMQCDAKFDFITRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCADC 99
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Mouse
Match: Zfyve21 (zinc finger, FYVE domain containing 21 [Source:MGI Symbol;Acc:MGI:1915770])

HSP 1 Score: 61.6178 bits (148), Expect = 1.883e-10
Identity = 28/70 (40.00%), Postives = 34/70 (48.57%), Query Frame = 1 
Query: 1648 LDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
              S F L  PQW  D   P+C  CD  F+   R+HHCRRCG  FC  C   K+ L  +     V  C +C
Sbjct:   30 FGSPFGLEEPQWVPDKECPRCMQCDAKFDFITRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCADC 99
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Mouse
Match: Zfyve21 (zinc finger, FYVE domain containing 21 [Source:MGI Symbol;Acc:MGI:1915770])

HSP 1 Score: 62.7734 bits (151), Expect = 1.986e-10
Identity = 28/68 (41.18%), Postives = 34/68 (50.00%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            S F L  PQW  D   P+C  CD  F+   R+HHCRRCG  FC  C   K+ L  +     V  C +C
Sbjct:   32 SPFGLEEPQWVPDKECPRCMQCDAKFDFITRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCADC 99
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Mouse
Match: Zfyve21 (zinc finger, FYVE domain containing 21 [Source:MGI Symbol;Acc:MGI:1915770])

HSP 1 Score: 63.1586 bits (152), Expect = 2.045e-10
Identity = 28/68 (41.18%), Postives = 34/68 (50.00%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            S F L  PQW  D   P+C  CD  F+   R+HHCRRCG  FC  C   K+ L  +     V  C +C
Sbjct:   43 SPFGLEEPQWVPDKECPRCMQCDAKFDFITRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCADC 110
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Mouse
Match: Rufy1 (RUN and FYVE domain containing 1 [Source:MGI Symbol;Acc:MGI:2429762])

HSP 1 Score: 59.3066 bits (142), Expect = 1.380e-8
Identity = 25/63 (39.68%), Postives = 35/63 (55.56%), Query Frame = 1 
Query: 1681 WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFL 1869
            W  D     C  C++ F+I RR+HHCR CG++FC++C   +L LP+     RV  C  C   L
Sbjct:  643 WLKDDEATHCKQCEKDFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRV--CDSCHTLL 703
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. UniProt/SwissProt
Match: sp|B0WAQ0|LST2_CULQU (Lateral signaling target protein 2 homolog OS=Culex quinquefasciatus OX=7176 GN=CPIJ004116 PE=3 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 3.581e-13
Identity = 30/66 (45.45%), Postives = 36/66 (54.55%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFLR 1872
            P+W  D   P+C  C  SF  FRRRHHCR CG +FC  C      LP  G+   V +C EC  F+R
Sbjct:  840 PRWIPDGDAPRCMACASSFTPFRRRHHCRNCGGVFCGGCSSASAPLPKYGLTKAVRVCREC--FVR 903

HSP 2 Score: 52.7582 bits (125), Expect = 9.817e-6
Identity = 33/92 (35.87%), Postives = 50/92 (54.35%), Query Frame = 1 
Query:  727 KELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPL 1002
            ++L + L  FD  FAEFEL +V  + +  + S    E+   + V+FSET+  A  + LLE   +   D  +M  IPR+ ++ G  I  EGPL
Sbjct:  158 EQLYESLKIFDRLFAEFELLYVSAMVQ--VKSKQEYEMQELICVLFSETLQRALKVGLLEQEQVDSYDPALMFSIPRLAIVAGLVIFKEGPL 247
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. UniProt/SwissProt
Match: sp|B4IC49|LST2_DROSE (Lateral signaling target protein 2 homolog OS=Drosophila sechellia OX=7238 GN=GM10129 PE=3 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 1.104e-12
Identity = 29/68 (42.65%), Postives = 35/68 (51.47%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +S  LS P W  D   P+C  C   F  FRRRHHCR CG +FC  C      LP  G+   V +C +C
Sbjct:  883 TSATLSPPAWIPDGKAPRCMACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDC 950

HSP 2 Score: 60.077 bits (144), Expect = 5.649e-8
Identity = 51/159 (32.08%), Postives = 86/159 (54.09%), Query Frame = 1 
Query:  727 KELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHXXXXXXXXXXXNALNIQEIHYLCKILMNHNEI----PQVSTSI 1191
            ++L + L  FD  FAEFEL +V  + +  + S H  E+   + V+FSET+  A  + LL+   +   D G+M  IPR+ ++ G  +  +GPL+   ++   D+     L+ +F+  R  L ++R  L  LN QE++ L K+L  + +I    P  S+SI
Sbjct:  157 EQLYESLKIFDRLFAEFELSYVSAMVQ--VKSRHEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLN---MDMPGDQ-----LSEMFRPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDINTKVPLGSSSI 305
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. UniProt/SwissProt
Match: sp|B3P851|LST2_DROER (Lateral signaling target protein 2 homolog OS=Drosophila erecta OX=7220 GN=GG12136 PE=3 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 1.248e-12
Identity = 29/68 (42.65%), Postives = 35/68 (51.47%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +S  LS P W  D   P+C  C   F  FRRRHHCR CG +FC  C      LP  G+   V +C +C
Sbjct:  889 TSATLSPPAWIPDGKAPRCMACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDC 956

HSP 2 Score: 60.4622 bits (145), Expect = 5.197e-8
Identity = 51/159 (32.08%), Postives = 86/159 (54.09%), Query Frame = 1 
Query:  727 KELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHXXXXXXXXXXXNALNIQEIHYLCKILMNHNEI----PQVSTSI 1191
            ++L + L  FD  FAEFEL +V  + +  + S H  E+   + V+FSET+  A  + LL+   +   D G+M  IPR+ ++ G  +  +GPL+   ++   D+     L+ +F+  R  L ++R  L  LN QE++ L K+L  + +I    P  S+SI
Sbjct:  166 EQLYESLKIFDRLFAEFELSYVSAMVQ--VKSRHEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLN---MDMPGDQ-----LSEMFRPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDINTKVPLGSSSI 314
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. UniProt/SwissProt
Match: sp|Q9VB70|LST2_DROME (Lateral signaling target protein 2 homolog OS=Drosophila melanogaster OX=7227 GN=CG6051 PE=1 SV=3)

HSP 1 Score: 75.485 bits (184), Expect = 1.253e-12
Identity = 29/68 (42.65%), Postives = 35/68 (51.47%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +S  LS P W  D   P+C  C   F  FRRRHHCR CG +FC  C      LP  G+   V +C +C
Sbjct:  897 TSATLSPPAWIPDGKAPRCMACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDC 964

HSP 2 Score: 60.4622 bits (145), Expect = 4.702e-8
Identity = 51/159 (32.08%), Postives = 86/159 (54.09%), Query Frame = 1 
Query:  727 KELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHXXXXXXXXXXXNALNIQEIHYLCKILMNHNEI----PQVSTSI 1191
            ++L + L  FD  FAEFEL +V  + +  + S H  E+   + V+FSET+  A  + LL+   +   D G+M  IPR+ ++ G  +  +GPL+   ++   D+     L+ +F+  R  L ++R  L  LN QE++ L K+L  + +I    P  S+SI
Sbjct:  166 EQLYESLKIFDRLFAEFELSYVSAMVQ--VKSRHEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLN---MDMPGDQ-----LSEMFRPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDINTKVPLGSSSI 314
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. UniProt/SwissProt
Match: sp|B4PRU6|LST2_DROYA (Lateral signaling target protein 2 homolog OS=Drosophila yakuba OX=7245 GN=GE10583 PE=3 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 1.294e-12
Identity = 29/68 (42.65%), Postives = 35/68 (51.47%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +S  LS P W  D   P+C  C   F  FRRRHHCR CG +FC  C      LP  G+   V +C +C
Sbjct:  892 TSATLSPPAWIPDGKAPRCMACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDC 959

HSP 2 Score: 60.077 bits (144), Expect = 5.764e-8
Identity = 51/159 (32.08%), Postives = 86/159 (54.09%), Query Frame = 1 
Query:  727 KELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHXXXXXXXXXXXNALNIQEIHYLCKILMNHNEI----PQVSTSI 1191
            ++L + L  FD  FAEFEL +V  + +  + S H  E+   + V+FSET+  A  + LL+   +   D G+M  IPR+ ++ G  +  +GPL+   ++   D+     L+ +F+  R  L ++R  L  LN QE++ L K+L  + +I    P  S+SI
Sbjct:  166 EQLYESLKIFDRLFAEFELSYVSAMVQ--VKSRHEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLN---MDMPGDQ-----LSEMFRPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDINTKVPLGSSSI 314
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. TrEMBL
Match: A0A1D1V6I9 (FYVE-type domain-containing protein OS=Ramazzottius varieornatus OX=947166 GN=RvY_05957-1 PE=4 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 7.899e-19
Identity = 110/422 (26.07%), Postives = 167/422 (39.57%), Query Frame = 1 
Query:  658 VKKLQSLTFQAIHSYYLMKSTLDKELMDMLLDFDNCFAEFELEFV---CQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAP-VFQEHXXXXXXXXXXXNALNIQEIHYLCKILMNHNEIPQVSTSIMNQSKFKAVDDQNIISGDMHALFKLISSVSDRMQS--KHASDYRFFMETIFKL------YKDEEDANSIQSVNNSNSFTTSDLFLSQYKNVMSKYTNIDEAVDALSYSLAEQFPDDRCCDLTILAQMESKTYLP---SPVQVNRENXXXXXXXXXXXXXXXXXLDSSFQLSR-------PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
             ++L +L       Y+   +T    +++ML  FD+ FAEFEL +V     V  +  Y +H+     DV V+FSET   A  +  +    I  CD  +M  IPR+ ++ G  +  EGPL           E +  L P +F+     L R++  L  LN +E+  L K L    E P V   IM ++    VDD ++   D+  +   +  +   + S  K ++  +F M    +         DEE A  +Q +  +  +     F S    +   Y  I    D L     + +  D    L  +  M S T  P   +  Q              T       L S+ + +R       P W  D     C  CD  F   RR+HHCR CG +FC  C    + LP   I   V +C  C
Sbjct:  140 TRQLDTLRVALREQYFRDATTYSDRVVEMLRVFDHMFAEFELSYVSAMVPVKTSKEYGLHQ-----DVIVLFSETTLRAMRLKFITADMIESCDPALMFTIPRLAIVAGLLVFPEGPLRI---------EQDAMLVPEMFRHFLRLLSRIKELLLTLNREELFTLEKCLCRAEE-PSV---IMKETL--GVDDISVQEYDIPVVHDYVEKLCRALPSLGKGSTLGKFSMPEENRTADSPTGLNDEELAMMLQRMEMAAHYEIRTKFRSSTDLIQRLYVCISGVADQLH----QNYASDLRSILKCIFDMHSDTSFPAKETAAQATTSPAVAIPADPSTSHYRQNLLVSAGERARSTTSKDPPAWIPDEQALLCAACDAPFTFVRRKHHCRNCGKVFCQQCSSNTIPLPHFQIQRPVRVCNNC 537
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. TrEMBL
Match: A0A267DZN0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021178g3 PE=4 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 3.688e-14
Identity = 99/417 (23.74%), Postives = 160/417 (38.37%), Query Frame = 1 
Query:  655 KVKKLQSLTFQAIH-----SYYLMKSTLDKELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVM---FSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHXXXXXXXXXXXNALNIQEIHYLCKILMNHNEIPQVSTSIMNQSKFKAVDDQNIISGDMHALFKLISSVSDRMQSKHASDYRFFMETIFKLYKDEEDANSIQSVNNSNSFTTSDLFLSQYKNVMSKYTNIDEAVDALSYSLAEQFPDDRCCDLTILAQMES-KTYLP-----SPVQVNRENXXXXXXXXXXXXXXXXXLDSSFQLSRPQWRTDSFFPKCCH--CDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            KV +    TFQ +      S++      +  L+  L  FD   ++FEL ++C      I      E  LD+  +   F     WA   N +     A C+  +M  +PR+ VL          +SE  ++  S      ++  VF+EHR              + E   L      H   PQ    +  +   +     +    +++ LF+ I+S +D++Q+ H  +  + M  +   Y  E  A   Q+   ++ F+     +       S  T+   A   + +SL +     R C  T  +   + K  LP     SPV+V              +    + L S      P+W  D   P+C +  C   F + RRRHHCR CG LFC SC     +LP  G +  V +C  C
Sbjct:  126 KVNEAAEDTFQMLRQEFGRSFHGGDPIHNVPLLQQLEKFDRFLSKFELAWICDGTNPDI-----VEALLDIQALSELFLRAASWAVEQNCINPEDFATCEPEIMTTLPRLAVLLY--------ISESTVDQGSG-----KVRKVFREHRE------------GLDEARKLL-----HRLEPQKRKEVAQRLCLRT----DARDPEINRLFRAIASAADQLQTNHPIECTYLMSYVCSKYSSEPQAEGEQAAVAASCFSIEPSVVLPD----SASTSCTSANCGVEFSLLQHRHHCRSCGGTFCSHCTTHKMPLPLLGHHSPVRV-------------CEPCRDKVLASMLTKEAPEWVPDCSSPRCSNGGCRVEFTLLRRRHHCRACGGLFCHSCSSWSASLPQFGYNEAVRLCQYC 486
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. TrEMBL
Match: A0A1I7SQ18 (FYVE-type domain-containing protein OS=Bursaphelenchus xylophilus OX=6326 PE=4 SV=1)

HSP 1 Score: 86.6557 bits (213), Expect = 6.262e-14
Identity = 90/378 (23.81%), Postives = 158/378 (41.80%), Query Frame = 1 
Query:  754 FDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHXXXXXXXXXXXNALNIQEIHYLCKILMNHNEIPQVSTSIMNQSKFKAVDDQNIISGDMHALFKLISSVSDRMQSKHASDYRFFMETIFKLYKDEEDANSI--QSVNNSNSFTTSDLFLSQYKNVMSKYTNIDEAVDALSY---SLAEQFPDDRCCDLTILAQMESKTYLPSPVQVNRENXXXXXXXXXXXXXXXXXLDSSFQLSRP-----QWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            FD  FAEFE  +V  +    + +I   +  LDVAV+F+E +  A          I + D  +M+ +PRI +L+G        L+ +  N     +  E ++ +F+                +  ++  L + L+N                   V+D+N I  + +    LI+ + +  ++   +D      T  KL    +D N I   ++N+ ++F  +D F++Q K       NID+ +  L      +A+Q   +   D+  + +M     +  PV+         +  ++ + I    ++    +S P     +W  D+    C  C  +F + RRRHHCR CG +FC  C G  L LP LG    V +C  C
Sbjct:  165 FDRLFAEFEFNYVSAMV--PVKTIVEYDHQLDVAVLFAECLNRALETGYFSKDQIEDADPTVMIALPRIAILWG--------LTTFEGNALDLNQGRENISEMFR----------------HFYDLLKLIRTLLN------------------LVEDENQILLENY----LITGIPEERRTLRENDISASALTTSKL----DDKNHILHAALNDMSNFELTDEFVTQAKK------NIDDVIHRLFVCICGVADQLQTNYSSDIRKILKM-----VLQPVETRPIYEISGKTAAVPQNIEETGVEVQESISLPTTTGVEWVPDADCDNCVACGSAFTLVRRRHHCRNCGRIFCYRCSGHALALPELGYERPVRVCNIC 479
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. TrEMBL
Match: A0A2L2YB56 (Lateral signaling target protein 2-like protein (Fragment) OS=Parasteatoda tepidariorum OX=114398 PE=2 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 1.698e-11
Identity = 58/233 (24.89%), Postives = 101/233 (43.35%), Query Frame = 1 
Query: 1198 QSKFKAVDDQNIISGDMHALFKLISSVSDRMQSKHASDYRFFMETIFKL--YKDEEDANSIQSVNNSNSFTTSDLFLSQYKNVMSKYTNIDEAVDALSYSLAEQF-----PDDRCCDLTILAQMESKTYLPSPV------QVNRENXXXXXXXXXXXXXXXXXLDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +S+FK+  D       +H LF  +S V+D++Q+ +ASD R  ++++F +   + +++       +NSN   + D+  +    + + ++  D     L+  ++E       PD+   D + +   E      SP        ++++N +     +                  P+W  D F P C  C   F I RRRHHCR CG +FCS C    + LP  G    V +C  C
Sbjct:  279 RSRFKSSRDL------LHKLFVCVSGVADQLQTNYASDLRNILKSVFDMNCSQSQQEVCDNSQTDNSNDINSPDVAWT-LPPISAAFS--DNGNSILTNEMSESLLNGNSPDEYDRDQSSVDSAEEVVADNSPTPSLVLPNISQQNENSIGVFT----------------GPPEWMPDEFSPNCMACKMQFTILRRRHHCRNCGKIFCSRCSSNTIALPHYGHLKPVRVCNHC 486
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. TrEMBL
Match: A0A4Y2II70 (Lateral signaling target protein 2 OS=Araneus ventricosus OX=182803 GN=zfyve28 PE=4 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 2.680e-11
Identity = 58/212 (27.36%), Postives = 88/212 (41.51%), Query Frame = 1 
Query: 1246 MHALFKLISSVSDRMQSKHASDYRFFMETIFKLYKDEEDA--NSIQSVNNSNSFTTSDLFLSQYKNVMSKYTNIDEAVDALSYSLAEQFPDDRCCDLTILAQMESKTYLPSPVQ------VNRENXXXXXXXXXXXXXXXXXLDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +H LF  +S V+D++Q+ +ASD R  ++ +F +  +++DA  NS    N S++     L    +    +  +N     D  S  L     DD   D + +   E      SP Q      + +EN +     +                  P+W  D     C  C   F I RRRHHCR CG +FCS C    + LP  G    V +C +C
Sbjct:  718 LHKLFVCVSGVADQLQTNYASDLRNILKCVFDMNCNQQDACDNSEPHENQSDNHEHGLLHEPNFSETNNHVSN-----DVSSTVLNNNQRDDDERDRSSVDSAEEAVPDNSPTQSLVIPNLGQENENNVGILN----------------GPPEWMPDELSSNCMACKVQFTILRRRHHCRNCGKIFCSRCSSNSIPLPRFGHLKPVRVCNQC 908
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Cavefish
Match: zfyve21 (zinc finger FYVE-type containing 21 [Source:NCBI gene;Acc:103023126])

HSP 1 Score: 67.0106 bits (162), Expect = 8.489e-12
Identity = 29/70 (41.43%), Postives = 35/70 (50.00%), Query Frame = 1 
Query: 1648 LDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
             +S F L  PQW  D    +C  CD  F+   R+HHCRRCG  FC  C   K+ LP +     V  C EC
Sbjct:   26 FNSPFSLDEPQWVPDKECARCMQCDTKFDFITRKHHCRRCGRCFCDKCCSKKVALPRMCFVDPVRQCAEC 95
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Cavefish
Match: zfyve28 (zinc finger FYVE-type containing 28 [Source:NCBI gene;Acc:103034700])

HSP 1 Score: 60.8474 bits (146), Expect = 4.668e-9
Identity = 25/64 (39.06%), Postives = 30/64 (46.88%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEF 1866
            P+W  D     C  C   F + RR+HHCR CG +FCS C      LP  G    V +C  C  F
Sbjct:  904 PEWVPDEACNSCIACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQMKPVRVCTHCYMF 967
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Cavefish
Match: zfyve28 (zinc finger FYVE-type containing 28 [Source:NCBI gene;Acc:103034700])

HSP 1 Score: 60.4622 bits (145), Expect = 4.946e-9
Identity = 24/61 (39.34%), Postives = 29/61 (47.54%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            P+W  D     C  C   F + RR+HHCR CG +FCS C      LP  G    V +C  C
Sbjct:  873 PEWVPDEACNSCIACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQMKPVRVCTHC 933
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Cavefish
Match: zfyve28 (zinc finger FYVE-type containing 28 [Source:NCBI gene;Acc:103034700])

HSP 1 Score: 60.4622 bits (145), Expect = 5.239e-9
Identity = 27/72 (37.50%), Postives = 33/72 (45.83%), Query Frame = 1 
Query: 1651 DSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEF 1866
            D  F+   P+W  D     C  C   F + RR+HHCR CG +FCS C      LP  G    V +C  C  F
Sbjct:  814 DGQFE-DPPEWVPDEACNSCIACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQMKPVRVCTHCYMF 884
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Cavefish
Match: rufy1 (RUN and FYVE domain containing 1 [Source:NCBI gene;Acc:103027503])

HSP 1 Score: 60.077 bits (144), Expect = 6.388e-9
Identity = 25/57 (43.86%), Postives = 33/57 (57.89%), Query Frame = 1 
Query: 1681 WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRV-SIC 1848
            W  D    +C  C + F+I RR+HHCR CG ++CSSC   +L LP+     RV  IC
Sbjct:  637 WLKDDEATQCKQCQKEFSISRRKHHCRNCGDIYCSSCSSNELALPSYPKPVRVCDIC 693
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001934.1 (pep scaffold:Pmarinus_7.0:GL488632:1056:3278:1 gene:ENSPMAG00000001758.1 transcript:ENSPMAT00000001934.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.299 bits (129), Expect = 3.226e-9
Identity = 23/53 (43.40%), Postives = 31/53 (58.49%), Query Frame = 1 
Query: 1681 WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRV 1839
            W  D     C  C++ F+I RR+HHCR CG +FC+SC   +L LP+     RV
Sbjct:   55 WLKDQDATNCKLCEKEFSISRRKHHCRNCGEIFCNSCSDNELPLPSSPKPVRV 107
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Sea Lamprey
Match: zfyve9a (zinc finger, FYVE domain containing 9a [Source:ZFIN;Acc:ZDB-GENE-070705-182])

HSP 1 Score: 53.9138 bits (128), Expect = 9.936e-8
Identity = 24/63 (38.10%), Postives = 31/63 (49.21%), Query Frame = 1 
Query: 1669 SRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            S P W  D+  P C  C   F   RRRHHCR CG +FC+ C   K  L  +  +    +C+ C
Sbjct:    6 SAPMWVPDAEAPNCMRCKARFTFTRRRHHCRACGKVFCAPCCSQKSRLRYME-NKEARVCIRC 67
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007717.1 (pep scaffold:Pmarinus_7.0:GL482293:11133:18546:-1 gene:ENSPMAG00000006971.1 transcript:ENSPMAT00000007717.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.1434 bits (126), Expect = 1.469e-7
Identity = 18/37 (48.65%), Postives = 22/37 (59.46%), Query Frame = 1 
Query: 1681 WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSC 1791
            W+ D    KC  C   F I  R+HHCR CG +FCS+C
Sbjct:  508 WQPDHNTKKCTSCKMEFGILTRKHHCRSCGLIFCSNC 544
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Sea Lamprey
Match: eea1 (early endosome antigen 1 [Source:ZFIN;Acc:ZDB-GENE-041111-270])

HSP 1 Score: 50.0618 bits (118), Expect = 1.782e-6
Identity = 25/69 (36.23%), Postives = 34/69 (49.28%), Query Frame = 1 
Query: 1666 LSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFLR 1872
            LSR +W  D     C  C + F++  R+HHCR CG +FC  C      +P+     RV  C  C E L+
Sbjct: 1303 LSR-KWAEDGEVQNCMGCGKGFSVTVRKHHCRHCGNIFCGECSARNSMIPSAKKPVRV--CDTCFEELK 1368
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Sea Lamprey
Match: zfyve21 (zinc finger, FYVE domain containing 21 [Source:ZFIN;Acc:ZDB-GENE-030131-1296])

HSP 1 Score: 46.9802 bits (110), Expect = 3.305e-6
Identity = 21/51 (41.18%), Postives = 26/51 (50.98%), Query Frame = 1 
Query: 1705 KCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +C  C+  F+   R+HHCRRCG  FC  C G K  LP +     V  C  C
Sbjct:    4 RCMLCEAKFDFLTRKHHCRRCGRCFCDRCCGRKAPLPRMSFVDPVRQCGTC 54
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Yeast
Match: FAB1 (1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis [Source:SGD;Acc:S000001915])

HSP 1 Score: 62.003 bits (149), Expect = 2.950e-10
Identity = 27/66 (40.91%), Postives = 37/66 (56.06%), Query Frame = 1 
Query: 1666 LSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEE 1863
            LS+  W  D    +C  C ++FN FRR+HHCR CG +FCSSC    +     G H ++ +C  C E
Sbjct:  232 LSKEYWMKDESSKECFSCGKTFNTFRRKHHCRICGQIFCSSC-TLLIDGDRFGCHAKMRVCYNCYE 296
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Yeast
Match: VPS27 (Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p) [Source:SGD;Acc:S000005289])

HSP 1 Score: 56.225 bits (134), Expect = 1.163e-8
Identity = 20/50 (40.00%), Postives = 28/50 (56.00%), Query Frame = 1 
Query: 1708 CCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            C  C + F++  R+HHCR CG +FC       + LP LGI+  V +C  C
Sbjct:  176 CMICSKKFSLLNRKHHCRSCGGVFCQEHSSNSIPLPDLGIYEPVRVCDSC 225
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Nematostella
Match: EDO25334 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DWS6])

HSP 1 Score: 50.8322 bits (120), Expect = 2.857e-8
Identity = 24/55 (43.64%), Postives = 32/55 (58.18%), Query Frame = 1 
Query: 1708 CCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFLR 1872
            C  C+ SF++F R HHCR CG  FC +C   ++TLP LG  T   +C  C   L+
Sbjct:   15 CAGCNTSFSVFFRPHHCRSCGGSFCEACSSKRMTLPRLGYDTFERVCDACYHALQ 69
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Nematostella
Match: EDO45897 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRW7])

HSP 1 Score: 56.6102 bits (135), Expect = 3.188e-8
Identity = 22/63 (34.92%), Postives = 32/63 (50.79%), Query Frame = 1 
Query: 1681 WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFL 1869
            W  D    +C  C   FN FRRRHHCR CG +FC  C   ++    +G +  + +C  C + +
Sbjct:  185 WMPDETCKECYECGEKFNTFRRRHHCRLCGQIFCYRCCNVEVPGQLMGYNGGLRVCTYCHKIV 247
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Nematostella
Match: EDO44864 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUJ2])

HSP 1 Score: 52.7582 bits (125), Expect = 1.583e-7
Identity = 24/64 (37.50%), Postives = 29/64 (45.31%), Query Frame = 1 
Query: 1669 SRPQWRTDSFFPKCCH-CDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            S P W         CH C   F  F R+HHCR CG +FC  C   +  +P  GI   V +C  C
Sbjct:  157 SAPAWAEGDV----CHMCRVKFGTFIRQHHCRNCGQVFCKKCSSKESIIPQFGIEKEVRVCDPC 216
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Nematostella
Match: EDO44969 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU81])

HSP 1 Score: 52.7582 bits (125), Expect = 2.139e-7
Identity = 20/54 (37.04%), Postives = 29/54 (53.70%), Query Frame = 1 
Query: 1678 QWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRV 1839
            +W  D     C  C++ F++ RR+HHCR CG +FC  C    + LP+     RV
Sbjct:  248 KWTDDKEALNCQQCEQPFSLSRRKHHCRSCGGIFCQPCSSNTMPLPSSAKPVRV 301
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Nematostella
Match: EDO44056 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWY7])

HSP 1 Score: 53.5286 bits (127), Expect = 2.570e-7
Identity = 24/64 (37.50%), Postives = 33/64 (51.56%), Query Frame = 1 
Query: 1669 SRPQ-WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            +RP  W  D+    C HC + F    R+HHCR CG  FC  C   + T+P+ G    V +C +C
Sbjct:  555 ARPGYWVPDALITNCHHCKQEFKGSDRKHHCRSCGQGFCDECSKQRRTVPSRGWDHPVRVCDKC 618
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Medaka
Match: zfyve21 (zinc finger FYVE-type containing 21 [Source:NCBI gene;Acc:101173424])

HSP 1 Score: 59.3066 bits (142), Expect = 2.010e-9
Identity = 27/68 (39.71%), Postives = 34/68 (50.00%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            S F L  PQW  D    +C  CD  F+  +R+HHCRRCG  FC  C   K+ L  +     V  C +C
Sbjct:   27 SPFCLEEPQWVPDKECHRCMQCDIKFDFMKRKHHCRRCGRCFCDKCCSKKVALDRMCFVDPVRHCADC 94
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Medaka
Match: zfyve9a (zinc finger FYVE-type containing 9 [Source:NCBI gene;Acc:101173656])

HSP 1 Score: 61.2326 bits (147), Expect = 3.682e-9
Identity = 26/65 (40.00%), Postives = 32/65 (49.23%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFL 1869
            P W  DS  P C  CD  F   +RRHHCR CG +FC++C   K  L  +       +CV C   L
Sbjct:  449 PVWVPDSQAPVCMKCDVKFTFTKRRHHCRACGKVFCAACCSLKCKLAYMD-RKEARVCVTCHSTL 512
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Medaka
Match: zfyve21 (zinc finger FYVE-type containing 21 [Source:NCBI gene;Acc:101173424])

HSP 1 Score: 58.5362 bits (140), Expect = 6.466e-9
Identity = 27/68 (39.71%), Postives = 34/68 (50.00%), Query Frame = 1 
Query: 1654 SSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVEC 1857
            S F L  PQW  D    +C  CD  F+  +R+HHCRRCG  FC  C   K+ L  +     V  C +C
Sbjct:   27 SPFCLEEPQWVPDKECHRCMQCDIKFDFMKRKHHCRRCGRCFCDKCCSKKVALDRMCFVDPVRHCADC 94
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Medaka
Match: zfyve28 (zinc finger FYVE-type containing 28 [Source:NCBI gene;Acc:101160946])

HSP 1 Score: 56.6102 bits (135), Expect = 1.256e-8
Identity = 25/64 (39.06%), Postives = 29/64 (45.31%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEF 1866
            P W  D     C  C   F + RR+HHCR CG +FCS C      LP  G    V +C  C  F
Sbjct:  136 PDWVPDDACNSCIACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMF 199
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Medaka
Match: rufy1 (RUN and FYVE domain-containing protein 1 [Source:NCBI gene;Acc:101155857])

HSP 1 Score: 58.5362 bits (140), Expect = 1.689e-8
Identity = 22/53 (41.51%), Postives = 31/53 (58.49%), Query Frame = 1 
Query: 1681 WRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRV 1839
            W  D    +C  C + F+I RR+HHCR CG ++C+SC   +L LP+     RV
Sbjct:  500 WLKDDEATQCKQCQKEFSIARRKHHCRNCGDIYCNSCSSNELALPSYPRPVRV 552
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Planmine SMEST
Match: SMESG000076100.1 (SMESG000076100.1)

HSP 1 Score: 1120.53 bits (2897), Expect = 0.000e+0
Identity = 580/581 (99.83%), Postives = 581/581 (100.00%), Query Frame = 1 
Query:  136 MSDKVYCELGKLIIDLLVNFERLQFSSGYDKVDNPNSIYLFYSSTLKLINKAISADQRDARIFRLKYHHILSNESVDEYLFHCLSKILSDLMDIENNYQKFIQPVADLHMKLMSIVTNLQVEHEKIVKANRLVQIEMQKRQEKKEIKGLDANNSDKIRAFNPVYFLPNNFTNKKVKKLQSLTFQAIHSYYLMKSTLDKELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHXXXXXXXXXXXNALNIQEIHYLCKILMNHNEIPQVSTSIMNQSKFKAVDDQNIISGDMHALFKLISSVSDRMQSKHASDYRFFMETIFKLYKDEEDANSIQSVNNSNSFTTSDLFLSQYKNVMSKYTNIDEAVDALSYSLAEQFPDDRCCDLTILAQMESKTYLPSPVQVNRENXXXXXXXXXXXXXXXXXLDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFLRGK 1878
            MSDKVYCELGKLIIDLLVNFERLQFSSGYDKVDNPNSIYLFYSSTLKLINKAISADQRDARIFRLKYHHILSNESVDEYLFHCLSKILSDLMDIENNYQKFIQPVADLHMKLMSIVTNLQVEHEKIVKANRLVQIEMQKRQEKKEIKGLDANNSDKIRAFNPVYFLPNNFTNKKVKKLQSLTFQAIHSYYLMKSTLDKELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHRLQLCRLRRQLNALNIQEIHYLCKILM+HNEIPQVSTSIMNQSKFKAVDDQNIISGDMHALFKLISSVSDRMQSKHASDYRFFMETIFKLYKDEEDANSIQSVNNSNSFTTSDLFLSQYKNVMSKYTNIDEAVDALSYSLAEQFPDDRCCDLTILAQMESKTYLPSPVQVNRENTSISRQQSITKQISTQSLDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFLRGK
Sbjct:    1 MSDKVYCELGKLIIDLLVNFERLQFSSGYDKVDNPNSIYLFYSSTLKLINKAISADQRDARIFRLKYHHILSNESVDEYLFHCLSKILSDLMDIENNYQKFIQPVADLHMKLMSIVTNLQVEHEKIVKANRLVQIEMQKRQEKKEIKGLDANNSDKIRAFNPVYFLPNNFTNKKVKKLQSLTFQAIHSYYLMKSTLDKELMDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWAHAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDEEIEERLAPVFQEHRLQLCRLRRQLNALNIQEIHYLCKILMDHNEIPQVSTSIMNQSKFKAVDDQNIISGDMHALFKLISSVSDRMQSKHASDYRFFMETIFKLYKDEEDANSIQSVNNSNSFTTSDLFLSQYKNVMSKYTNIDEAVDALSYSLAEQFPDDRCCDLTILAQMESKTYLPSPVQVNRENTSISRQQSITKQISTQSLDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFLRGK 581
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Planmine SMEST
Match: SMESG000066383.1 (SMESG000066383.1)

HSP 1 Score: 62.3882 bits (150), Expect = 8.572e-10
Identity = 23/67 (34.33%), Postives = 35/67 (52.24%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFLRG 1875
            P+W+       C  C  +F+  +R+HHCR CG +FC  C   +  +P  GI   V +C  C E ++G
Sbjct:  158 PEWQDAD---TCYRCKIAFSALKRKHHCRHCGNIFCDECTSKRSNIPKYGIEKEVRVCESCYESIKG 221
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Planmine SMEST
Match: SMESG000066383.1 (SMESG000066383.1)

HSP 1 Score: 62.3882 bits (150), Expect = 1.070e-9
Identity = 23/67 (34.33%), Postives = 35/67 (52.24%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFLRG 1875
            P+W+       C  C  +F+  +R+HHCR CG +FC  C   +  +P  GI   V +C  C E ++G
Sbjct:  158 PEWQDAD---TCYRCKIAFSALKRKHHCRHCGNIFCDECTSKRSNIPKYGIEKEVRVCESCYESIKG 221
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Planmine SMEST
Match: SMESG000066383.1 (SMESG000066383.1)

HSP 1 Score: 62.003 bits (149), Expect = 1.157e-9
Identity = 23/67 (34.33%), Postives = 35/67 (52.24%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFLRG 1875
            P+W+       C  C  +F+  +R+HHCR CG +FC  C   +  +P  GI   V +C  C E ++G
Sbjct:  158 PEWQDAD---TCYRCKIAFSALKRKHHCRHCGNIFCDECTSKRSNIPKYGIEKEVRVCESCYESIKG 221
[Close]
BLAST of Lateral signaling target protein 2 homolog vs. Planmine SMEST
Match: SMESG000066383.1 (SMESG000066383.1)

HSP 1 Score: 62.003 bits (149), Expect = 1.237e-9
Identity = 23/67 (34.33%), Postives = 35/67 (52.24%), Query Frame = 1 
Query: 1675 PQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCSSCWGTKLTLPTLGIHTRVSICVECEEFLRG 1875
            P+W+       C  C  +F+  +R+HHCR CG +FC  C   +  +P  GI   V +C  C E ++G
Sbjct:  158 PEWQDAD---TCYRCKIAFSALKRKHHCRHCGNIFCDECTSKRSNIPKYGIEKEVRVCESCYESIKG 221
The following BLAST results are available for this feature:
BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ZFYVE211.424e-940.00zinc finger FYVE-type containing 21 [Source:HGNC S... [more]
ZFYVE211.488e-940.00zinc finger FYVE-type containing 21 [Source:HGNC S... [more]
RUFY11.580e-839.68RUN and FYVE domain containing 1 [Source:HGNC Symb... [more]
RUFY11.580e-839.68RUN and FYVE domain containing 1 [Source:HGNC Symb... [more]
RUFY11.580e-839.68RUN and FYVE domain containing 1 [Source:HGNC Symb... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hgrs-19.932e-1141.27Hepatocyte Growth factor-Regulated TK Substrate (H... [more]
hgrs-19.932e-1141.27Hepatocyte Growth factor-Regulated TK Substrate (H... [more]
lst-24.899e-1025.81Lateral signaling target protein 2 [Source:UniPro... [more]
ppk-31.995e-837.68PIP Kinase [Source:UniProtKB/TrEMBL;Acc:G5ED98][more]
aka-15.431e-837.97A Kinase Anchor protein [Source:UniProtKB/TrEMBL;... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG60511.250e-1342.65gene:FBgn0039492 transcript:FBtr0305050[more]
CG60511.250e-1342.65gene:FBgn0039492 transcript:FBtr0113297[more]
CG60511.271e-1342.65gene:FBgn0039492 transcript:FBtr0339264[more]
CG310643.394e-941.27gene:FBgn0051064 transcript:FBtr0339249[more]
CG310645.205e-941.27gene:FBgn0051064 transcript:FBtr0085125[more]
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BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zfyve214.175e-1342.86zinc finger, FYVE domain containing 21 [Source:ZFI... [more]
zfyve214.226e-1342.86zinc finger, FYVE domain containing 21 [Source:ZFI... [more]
zfyve287.170e-939.06zinc finger, FYVE domain containing 28 [Source:NCB... [more]
hgs7.730e-937.66hepatocyte growth factor-regulated tyrosine kinase... [more]
zfyve9b1.071e-840.28zinc finger, FYVE domain containing 9b [Source:ZFI... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zfyve211.107e-1245.59Xenopus tropicalis zinc finger FYVE-type containin... [more]
zfyve211.113e-1245.59Xenopus tropicalis zinc finger FYVE-type containin... [more]
zfyve211.493e-1245.59Xenopus tropicalis zinc finger FYVE-type containin... [more]
rita14.111e-944.26RBPJ interacting and tubulin associated 1 [Source:... [more]
rps184.130e-943.55ribosomal protein S18 [Source:Xenbase;Acc:XB-GENE-... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Zfyve211.803e-1041.18zinc finger, FYVE domain containing 21 [Source:MGI... [more]
Zfyve211.883e-1040.00zinc finger, FYVE domain containing 21 [Source:MGI... [more]
Zfyve211.986e-1041.18zinc finger, FYVE domain containing 21 [Source:MGI... [more]
Zfyve212.045e-1041.18zinc finger, FYVE domain containing 21 [Source:MGI... [more]
Rufy11.380e-839.68RUN and FYVE domain containing 1 [Source:MGI Symbo... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|B0WAQ0|LST2_CULQU3.581e-1345.45Lateral signaling target protein 2 homolog OS=Cule... [more]
sp|B4IC49|LST2_DROSE1.104e-1242.65Lateral signaling target protein 2 homolog OS=Dros... [more]
sp|B3P851|LST2_DROER1.248e-1242.65Lateral signaling target protein 2 homolog OS=Dros... [more]
sp|Q9VB70|LST2_DROME1.253e-1242.65Lateral signaling target protein 2 homolog OS=Dros... [more]
sp|B4PRU6|LST2_DROYA1.294e-1242.65Lateral signaling target protein 2 homolog OS=Dros... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1D1V6I97.899e-1926.07FYVE-type domain-containing protein OS=Ramazzottiu... [more]
A0A267DZN03.688e-1423.74Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I7SQ186.262e-1423.81FYVE-type domain-containing protein OS=Bursaphelen... [more]
A0A2L2YB561.698e-1124.89Lateral signaling target protein 2-like protein (F... [more]
A0A4Y2II702.680e-1127.36Lateral signaling target protein 2 OS=Araneus vent... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zfyve218.489e-1241.43zinc finger FYVE-type containing 21 [Source:NCBI g... [more]
zfyve284.668e-939.06zinc finger FYVE-type containing 28 [Source:NCBI g... [more]
zfyve284.946e-939.34zinc finger FYVE-type containing 28 [Source:NCBI g... [more]
zfyve285.239e-937.50zinc finger FYVE-type containing 28 [Source:NCBI g... [more]
rufy16.388e-943.86RUN and FYVE domain containing 1 [Source:NCBI gene... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000001934.13.226e-943.40pep scaffold:Pmarinus_7.0:GL488632:1056:3278:1 gen... [more]
zfyve9a9.936e-838.10zinc finger, FYVE domain containing 9a [Source:ZFI... [more]
ENSPMAT00000007717.11.469e-748.65pep scaffold:Pmarinus_7.0:GL482293:11133:18546:-1 ... [more]
eea11.782e-636.23early endosome antigen 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
zfyve213.305e-641.18zinc finger, FYVE domain containing 21 [Source:ZFI... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
FAB12.950e-1040.911-phosphatidylinositol-3-phosphate 5-kinase; vacuo... [more]
VPS271.163e-840.00Endosomal protein that forms a complex with Hse1p;... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO253342.857e-843.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8... [more]
EDO458973.188e-834.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO448641.583e-737.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449692.139e-737.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO440562.570e-737.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zfyve212.010e-939.71zinc finger FYVE-type containing 21 [Source:NCBI g... [more]
zfyve9a3.682e-940.00zinc finger FYVE-type containing 9 [Source:NCBI ge... [more]
zfyve216.466e-939.71zinc finger FYVE-type containing 21 [Source:NCBI g... [more]
zfyve281.256e-839.06zinc finger FYVE-type containing 28 [Source:NCBI g... [more]
rufy11.689e-841.51RUN and FYVE domain-containing protein 1 [Source:N... [more]
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BLAST of Lateral signaling target protein 2 homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000076100.10.000e+099.83SMESG000076100.1[more]
SMESG000066383.18.572e-1034.33SMESG000066383.1[more]
SMESG000066383.11.070e-934.33SMESG000066383.1[more]
SMESG000066383.11.157e-934.33SMESG000066383.1[more]
SMESG000066383.11.237e-934.33SMESG000066383.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004461 ID=SMED30004461|Name=Lateral signaling target protein 2 homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=2093bp
TTCTTTAAATGTATGAGATTATTAAATAAAGTTATTCACATTATTTATAT
CTAAATTCATTTTTTGGAATTATCAATTGCTTATTATTAAACGAAAAGTG
ATTAGTATTTTTAAAGCTGCTAGATATTACAAATAATGTCAGACAAAGTT
TATTGTGAATTAGGAAAACTTATAATTGATTTATTAGTCAATTTTGAACG
ATTGCAGTTTTCTAGTGGATATGATAAAGTTGATAATCCGAATTCCATTT
ATTTATTTTATTCGTCAACTTTAAAGCTTATCAATAAAGCAATTTCTGCT
GATCAACGAGATGCGAGAATTTTTCGATTGAAATATCACCATATTTTGTC
AAATGAAAGCGTTGATGAGTATTTATTTCATTGTTTATCAAAAATTCTAT
CAGATCTGATGGACATCGAAAACAATTATCAAAAGTTTATCCAACCTGTA
GCTGATCTGCACATGAAATTAATGTCAATCGTCACAAATTTACAAGTCGA
GCACGAAAAGATCGTTAAAGCAAATCGTTTGGTGCAGATTGAAATGCAGA
AAAGACAAGAAAAGAAAGAAATTAAAGGATTAGATGCAAATAATTCTGAC
AAAATTCGAGCGTTCAATCCAGTTTATTTCCTTCCAAACAATTTCACTAA
CAAAAAGGTTAAAAAACTTCAAAGCCTTACATTTCAGGCCATACACAGTT
ATTATTTGATGAAATCCACGTTGGACAAAGAATTGATGGACATGTTGTTG
GATTTTGATAATTGCTTTGCTGAATTCGAATTGGAATTTGTTTGTCAAGT
GAATAAAAATTCTATCTATTCTATTCATCGCGCGGAATTAACTTTGGATG
TTGCTGTTATGTTCTCCGAGACTGTGTATTGGGCCCATGCCATGAATTTG
CTGGAATATCGAGCAATTGCTGAGTGTGATATTGGAATGATGGTGGGAAT
TCCGCGAATAACTGTTCTTTATGGTTGTGGAATAGCAAATGAAGGTCCTT
TATCGGAATGGGCACTGAATTGTCACAGTGATGAGGAAATTGAAGAACGC
TTAGCTCCAGTATTTCAGGAACACAGATTACAATTATGTCGTTTACGCCG
TCAACTTAACGCATTGAATATTCAGGAAATACATTACCTTTGCAAGATAT
TGATGAACCATAATGAGATACCGCAAGTTTCGACCAGCATAATGAATCAG
AGTAAATTTAAAGCAGTTGATGACCAGAACATTATTTCTGGAGACATGCA
CGCTCTCTTTAAATTGATCAGCTCGGTTTCTGATCGGATGCAGTCTAAAC
ACGCTTCAGATTACAGGTTTTTTATGGAGACCATATTTAAACTGTATAAA
GATGAAGAGGATGCCAATTCCATTCAATCAGTGAATAACTCAAATTCTTT
CACGACTTCAGATTTATTTCTATCCCAATACAAAAATGTTATGTCAAAAT
ATACGAACATTGATGAAGCTGTTGATGCATTGAGTTATTCGCTAGCAGAA
CAATTTCCCGATGACCGATGCTGTGATCTAACAATTCTTGCTCAGATGGA
GTCCAAAACATATCTCCCGTCTCCAGTTCAAGTCAATAGAGAAAATACAT
CCATTTCCCGACAACAATCTATTACAAAACAAATTTCTACTCAAAGTCTT
GATTCCAGTTTTCAACTTAGCCGACCTCAATGGAGAACAGACTCATTTTT
TCCAAAATGTTGCCACTGTGACAGGAGTTTTAACATATTTCGGCGCAGGC
ATCATTGTAGAAGATGTGGATATTTATTTTGTAGTTCTTGTTGGGGAACA
AAACTCACCCTTCCTACACTTGGCATCCATACTAGAGTTTCGATCTGTGT
TGAATGTGAAGAATTTCTCAGAGGGAAAGCTACCCAATCCACAACATCCC
CACAAAGTGCTTCGACGAGTTGAATATTAATTTCGTCTGTCCTATTTCAG
ATTTTAACTTGCTCATGAATCAGAATTATTTAAATATAAAATTTTTATTT
GTTAATTTTTGTAAGGAGCTATTTAATTATCTGGAGGGTGAAATTTTGCG
GAAATTGATGAAATATTGCGGTGATCTGTCGGTTCATTCCTGT
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protein sequence of SMED30004461-orf-1

>SMED30004461-orf-1 ID=SMED30004461-orf-1|Name=SMED30004461-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=596bp
MSDKVYCELGKLIIDLLVNFERLQFSSGYDKVDNPNSIYLFYSSTLKLIN
KAISADQRDARIFRLKYHHILSNESVDEYLFHCLSKILSDLMDIENNYQK
FIQPVADLHMKLMSIVTNLQVEHEKIVKANRLVQIEMQKRQEKKEIKGLD
ANNSDKIRAFNPVYFLPNNFTNKKVKKLQSLTFQAIHSYYLMKSTLDKEL
MDMLLDFDNCFAEFELEFVCQVNKNSIYSIHRAELTLDVAVMFSETVYWA
HAMNLLEYRAIAECDIGMMVGIPRITVLYGCGIANEGPLSEWALNCHSDE
EIEERLAPVFQEHRLQLCRLRRQLNALNIQEIHYLCKILMNHNEIPQVST
SIMNQSKFKAVDDQNIISGDMHALFKLISSVSDRMQSKHASDYRFFMETI
FKLYKDEEDANSIQSVNNSNSFTTSDLFLSQYKNVMSKYTNIDEAVDALS
YSLAEQFPDDRCCDLTILAQMESKTYLPSPVQVNRENTSISRQQSITKQI
STQSLDSSFQLSRPQWRTDSFFPKCCHCDRSFNIFRRRHHCRRCGYLFCS
SCWGTKLTLPTLGIHTRVSICVECEEFLRGKATQSTTSPQSASTS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR000306Znf_FYVE
IPR013083Znf_RING/FYVE/PHD
IPR017455Znf_FYVE-rel
IPR011011Znf_FYVE_PHD
Vocabulary: molecular function
TermDefinition
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 132..152
NoneNo IPR availablePANTHERPTHR46465FAMILY NOT NAMEDcoord: 366..578
coord: 184..346
IPR000306FYVE zinc fingerSMARTSM00064fyve_4coord: 511..580
e-value: 2.4E-13
score: 60.3
IPR000306FYVE zinc fingerPFAMPF01363FYVEcoord: 515..576
e-value: 1.4E-13
score: 50.8
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 505..584
e-value: 1.3E-17
score: 65.3
IPR017455Zinc finger, FYVE-relatedPROSITEPS50178ZF_FYVEcoord: 519..579
score: 11.797
IPR011011Zinc finger, FYVE/PHD-typeSUPERFAMILYSSF57903FYVE/PHD zinc fingercoord: 514..580