B-cell lymphoma/leukemia 11B

Overview


Name	B-cell lymphoma/leukemia 11B
Smed ID	SMED30004449
Length (bp)	1774

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of B-cell lymphoma/leukemia 11B (SMED30004449) t-SNE clustered cells

Violin plots show distribution of expression levels for B-cell lymphoma/leukemia 11B (SMED30004449) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of B-cell lymphoma/leukemia 11B (SMED30004449) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for B-cell lymphoma/leukemia 11B (SMED30004449) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30004449

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 16

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30004449	SMESG000029867.1	SmedASXL_007595	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
head region	SMED30004449	SMESG000029867.1	SmedASXL_000382	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
nervous system	SMED30004449	SMESG000029867.1	dd_Smed_v4_16598_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30004449	SMESG000029867.1	dd_Smed_v4_16598_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30004449	SMESG000029867.1	dd_Smed_v4_16598_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30004449	SMESG000029867.1	dd_Smed_v4_16598_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30004449	SMESG000029867.1	dd_Smed_v4_16598_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30004449	SMESG000029867.1	dd_Smed_v4_10320_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30004449	SMESG000029867.1	dd_Smed_v4_10320_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30004449	SMESG000029867.1	dd_Smed_v4_10320_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30004449	SMESG000029867.1	dd_Smed_v4_10320_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30004449	SMESG000029867.1	dd_Smed_v4_10320_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30004449	SMESG000029867.1	dd_Smed_v4_10320_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30004449	SMESG000029867.1	dd_Smed_v6_16598_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30004449	SMESG000029867.1	dd_Smed_v6_10320_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
pharynx musculature	SMED30004449	SMESG000029867.1	dd_Smed_v4_10320_0_1	dd_Smed_v4	PMID:30471994 Scimone et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Human
Match: BCL11A (BAF chromatin remodeling complex subunit BCL11A [Source:HGNC Symbol;Acc:HGNC:13221])

HSP 1 Score: 139.428 bits (350), Expect = 5.892e-34
Identity = 65/99 (65.66%), Postives = 75/99 (75.76%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNSFGT 1593
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C+ C  PF V +TLEKHM+K     S+R L N   T
Sbjct:  739 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKDVYKCEICKMPFSVYSTLEKHMKKW---HSDRVLNNDIKT 834

HSP 2 Score: 88.5817 bits (218), Expect = 1.294e-17
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C+LC +AC Q+SKL RHMKTH
Sbjct:  375 KSKSCEFCGKTFKFQSNLVVHRRSHTGEKPYKCNLCDHACTQASKLKRHMKTH 427

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Human
Match: BCL11A (BAF chromatin remodeling complex subunit BCL11A [Source:HGNC Symbol;Acc:HGNC:13221])

HSP 1 Score: 138.658 bits (348), Expect = 1.070e-33
Identity = 65/99 (65.66%), Postives = 75/99 (75.76%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNSFGT 1593
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C+ C  PF V +TLEKHM+K     S+R L N   T
Sbjct:  705 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKDVYKCEICKMPFSVYSTLEKHMKKW---HSDRVLNNDIKT 800

HSP 2 Score: 88.1965 bits (217), Expect = 1.763e-17
Identity = 37/50 (74.00%), Postives = 43/50 (86.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +CEFCGK F+  SNL VHRRSHTGEKPY+C+LC +AC Q+SKL RHMKTH
Sbjct:  344 SCEFCGKTFKFQSNLVVHRRSHTGEKPYKCNLCDHACTQASKLKRHMKTH 393

HSP 3 Score: 58.151 bits (139), Expect = 3.514e-8
Identity = 43/164 (26.22%), Postives = 63/164 (38.41%), Query Frame = 1

Query:  364 MSRRKQIQPQQL--------FIES------------NSVSSDIDYITCGECQKTFEFENIMVFLTHKMFHMKGSI--------TDSPGKIGLLSSRNYLPTSILSKKESNN-------------------NYKECIQCCHCWKFFGSAWKLLQHVQRNHKISVY 714
            MSRRKQ +PQ L         +E+             +   D D +TCG+CQ  F   +I++F+ HK     GS+          SP  I +  + N +   I    E ++                   +      C  C + F SAW LLQH Q  H + +Y
Sbjct:    1 MSRRKQGKPQHLSKREFSPEPLEAILTDDEPDHGPLGAPEGDHDLLTCGQCQMNFPLGDILIFIEHKRKQCNGSLCLEKAVDKPPSPSPIEMKKASNPVEVGIQVTPEDDDCLSTSSRGICPKQEHIAGKDEPSSYTCTTCKQPFTSAWFLLQHAQNTHGLRIY 164

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BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Human
Match: BCL11B (BAF chromatin remodeling complex subunit BCL11B [Source:HGNC Symbol;Acc:HGNC:13222])

HSP 1 Score: 137.502 bits (345), Expect = 1.958e-33
Identity = 60/84 (71.43%), Postives = 68/84 (80.95%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKC 1548
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K 
Sbjct:  599 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKKW 682

HSP 2 Score: 89.3521 bits (220), Expect = 6.326e-18
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  231 KSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 283

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Human
Match: BCL11B (BAF chromatin remodeling complex subunit BCL11B [Source:HGNC Symbol;Acc:HGNC:13222])

HSP 1 Score: 137.502 bits (345), Expect = 2.462e-33
Identity = 60/83 (72.29%), Postives = 68/83 (81.93%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K
Sbjct:  722 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKK 804

HSP 2 Score: 89.3521 bits (220), Expect = 6.372e-18
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  354 KSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 406

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Human
Match: BCL11B (BAF chromatin remodeling complex subunit BCL11B [Source:HGNC Symbol;Acc:HGNC:13222])

HSP 1 Score: 137.502 bits (345), Expect = 2.619e-33
Identity = 60/83 (72.29%), Postives = 68/83 (81.93%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K
Sbjct:  793 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKK 875

HSP 2 Score: 89.3521 bits (220), Expect = 6.745e-18
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  425 KSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 477

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BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Celegans
Match: bcl-11 (Mammalian BCL (B cell lymphoma) gene homologs [Source:UniProtKB/TrEMBL;Acc:H2KZR6])

HSP 1 Score: 133.65 bits (335), Expect = 1.087e-32
Identity = 64/112 (57.14%), Postives = 76/112 (67.86%), Query Frame = 1

Query: 1249 EISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNS 1584
            E++  A    + I+KE+    C FC KVF N SNL VH RSHTGEKPY+C LC YACAQSSKLTRHM+THG++G  + HC  C  PF V +TLEKHMRKC +    R  G S
Sbjct:  483 ELAEPAARKPNNIKKER----CNFCNKVFTNRSNLIVHLRSHTGEKPYKCQLCPYACAQSSKLTRHMRTHGQQGKETYHCYICRMPFSVHSTLEKHMRKCVVSTQGRREGGS 590

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Query: 1249 EISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNS 1584
            E++  A    + I+KE+    C FC KVF N SNL VH RSHTGEKPY+C LC YACAQSSKLTRHM+THG++G  + HC  C  PF V +TLEKHMRKC +    R  G S
Sbjct:  483 ELAEPAARKPNNIKKER----CNFCNKVFTNRSNLIVHLRSHTGEKPYKCQLCPYACAQSSKLTRHMRTHGQQGKETYHCYICRMPFSVHSTLEKHMRKCVVSTQGRREGGS 590

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Celegans
Match: bcl-11 (Mammalian BCL (B cell lymphoma) gene homologs [Source:UniProtKB/TrEMBL;Acc:H2KZR6])

HSP 1 Score: 133.65 bits (335), Expect = 1.141e-32
Identity = 64/112 (57.14%), Postives = 76/112 (67.86%), Query Frame = 1

Query: 1249 EISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNS 1584
            E++  A    + I+KE+    C FC KVF N SNL VH RSHTGEKPY+C LC YACAQSSKLTRHM+THG++G  + HC  C  PF V +TLEKHMRKC +    R  G S
Sbjct:  479 ELAEPAARKPNNIKKER----CNFCNKVFTNRSNLIVHLRSHTGEKPYKCQLCPYACAQSSKLTRHMRTHGQQGKETYHCYICRMPFSVHSTLEKHMRKCVVSTQGRREGGS 586

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BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Celegans
Match: che-1 (Transcription factor che-1 [Source:UniProtKB/Swiss-Prot;Acc:Q966L8])

HSP 1 Score: 71.633 bits (174), Expect = 1.571e-13
Identity = 35/77 (45.45%), Postives = 45/77 (58.44%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C+ CGK F   +NLT H+R HTGEKP+ C +C    +QSS L  H +TH   G R   C  C   F  ++TL KH+R
Sbjct:  168 CQTCGKAFSQAANLTAHKRIHTGEKPFMCPVCNRPFSQSSSLVTHRRTH--TGERPYPCAQCEKAFTDSSTLTKHLR 242

HSP 2 Score: 66.2402 bits (160), Expect = 9.380e-12
Identity = 36/99 (36.36%), Postives = 51/99 (51.52%), Query Frame = 1

Query: 1264 AFNCGSEIEKEKRQDT------CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            AF+  + +   KR  T      C  C + F   S+L  HRR+HTGE+PY C  C+ A   SS LT+H++TH   G +   C  C   F  +  L +HM+
Sbjct:  174 AFSQAANLTAHKRIHTGEKPFMCPVCNRPFSQSSSLVTHRRTHTGERPYPCAQCEKAFTDSSTLTKHLRTH--TGHKPYVCSICMMKFTQSGNLHRHMK 270

HSP 3 Score: 56.6102 bits (135), Expect = 1.397e-8
Identity = 31/75 (41.33%), Postives = 38/75 (50.67%), Query Frame = 1

Query: 1252 ISNVAFNCGSEIEKEKRQDT------CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            + N  F+  S +   +R  T      C  C K F + S LT H R+HTG KPY C +C     QS  L RHMKTH
Sbjct:  198 VCNRPFSQSSSLVTHRRTHTGERPYPCAQCEKAFTDSSTLTKHLRTHTGHKPYVCSICMMKFTQSGNLHRHMKTH 272

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Celegans
Match: che-1 (Transcription factor che-1 [Source:UniProtKB/Swiss-Prot;Acc:Q966L8])

HSP 1 Score: 69.707 bits (169), Expect = 2.162e-13
Identity = 35/77 (45.45%), Postives = 45/77 (58.44%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C+ CGK F   +NLT H+R HTGEKP+ C +C    +QSS L  H +TH  E  R   C  C   F  ++TL KH+R
Sbjct:  109 CQTCGKAFSQAANLTAHKRIHTGEKPFMCPVCNRPFSQSSSLVTHRRTHTGE--RPYPCAQCEKAFTDSSTLTKHLR 183

HSP 2 Score: 64.3142 bits (155), Expect = 1.615e-11
Identity = 36/99 (36.36%), Postives = 51/99 (51.52%), Query Frame = 1

Query: 1264 AFNCGSEIEKEKRQDT------CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            AF+  + +   KR  T      C  C + F   S+L  HRR+HTGE+PY C  C+ A   SS LT+H++TH   G +   C  C   F  +  L +HM+
Sbjct:  115 AFSQAANLTAHKRIHTGEKPFMCPVCNRPFSQSSSLVTHRRTHTGERPYPCAQCEKAFTDSSTLTKHLRTH--TGHKPYVCSICMMKFTQSGNLHRHMK 211

HSP 3 Score: 55.4546 bits (132), Expect = 1.559e-8
Identity = 31/75 (41.33%), Postives = 38/75 (50.67%), Query Frame = 1

Query: 1252 ISNVAFNCGSEIEKEKRQDT------CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            + N  F+  S +   +R  T      C  C K F + S LT H R+HTG KPY C +C     QS  L RHMKTH
Sbjct:  139 VCNRPFSQSSSLVTHRRTHTGERPYPCAQCEKAFTDSSTLTKHLRTHTGHKPYVCSICMMKFTQSGNLHRHMKTH 213

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BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Fly
Match: CG9650 (gene:FBgn0029939 transcript:FBtr0339815)

HSP 1 Score: 156.377 bits (394), Expect = 9.395e-40
Identity = 69/97 (71.13%), Postives = 78/97 (80.41%), Query Frame = 1

Query: 1276 GSEIEKEKRQ--DTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRE 1560
            G  ++KE RQ  DTCEFCGKVF+NCSNLTVHRRSHTGEKPY+C LC YACAQSSKLTRHMKTHGR G     C++C  PF V +TLEKHMRKC + +
Sbjct:  943 GPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQ 1039

HSP 2 Score: 64.6994 bits (156), Expect = 1.957e-10
Identity = 24/50 (48.00%), Postives = 35/50 (70.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +C +C K FR  +NL +H+R+HTGEKPY+C  C + C+   KL +HM+ H
Sbjct:  645 SCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVH 694

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Fly
Match: CG9650 (gene:FBgn0029939 transcript:FBtr0309030)

HSP 1 Score: 156.377 bits (394), Expect = 1.227e-39
Identity = 69/97 (71.13%), Postives = 78/97 (80.41%), Query Frame = 1

Query: 1276 GSEIEKEKRQ--DTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRE 1560
            G  ++KE RQ  DTCEFCGKVF+NCSNLTVHRRSHTGEKPY+C LC YACAQSSKLTRHMKTHGR G     C++C  PF V +TLEKHMRKC + +
Sbjct: 1010 GPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQ 1106

HSP 2 Score: 64.6994 bits (156), Expect = 2.039e-10
Identity = 24/50 (48.00%), Postives = 35/50 (70.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +C +C K FR  +NL +H+R+HTGEKPY+C  C + C+   KL +HM+ H
Sbjct:  712 SCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVH 761

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Fly
Match: CG9650 (gene:FBgn0029939 transcript:FBtr0301240)

HSP 1 Score: 156.377 bits (394), Expect = 1.240e-39
Identity = 69/97 (71.13%), Postives = 78/97 (80.41%), Query Frame = 1

Query: 1276 GSEIEKEKRQ--DTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRE 1560
            G  ++KE RQ  DTCEFCGKVF+NCSNLTVHRRSHTGEKPY+C LC YACAQSSKLTRHMKTHGR G     C++C  PF V +TLEKHMRKC + +
Sbjct: 1012 GPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQ 1108

HSP 2 Score: 64.6994 bits (156), Expect = 2.076e-10
Identity = 24/50 (48.00%), Postives = 35/50 (70.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +C +C K FR  +NL +H+R+HTGEKPY+C  C + C+   KL +HM+ H
Sbjct:  714 SCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVH 763

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Fly
Match: CG9650 (gene:FBgn0029939 transcript:FBtr0474235)

HSP 1 Score: 155.992 bits (393), Expect = 1.492e-39
Identity = 69/97 (71.13%), Postives = 78/97 (80.41%), Query Frame = 1

Query: 1276 GSEIEKEKRQ--DTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRE 1560
            G  ++KE RQ  DTCEFCGKVF+NCSNLTVHRRSHTGEKPY+C LC YACAQSSKLTRHMKTHGR G     C++C  PF V +TLEKHMRKC + +
Sbjct: 1016 GPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQ 1112

HSP 2 Score: 64.6994 bits (156), Expect = 2.095e-10
Identity = 24/50 (48.00%), Postives = 35/50 (70.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +C +C K FR  +NL +H+R+HTGEKPY+C  C + C+   KL +HM+ H
Sbjct:  718 SCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVH 767

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Fly
Match: CG9650 (gene:FBgn0029939 transcript:FBtr0474234)

HSP 1 Score: 155.992 bits (393), Expect = 1.509e-39
Identity = 69/97 (71.13%), Postives = 78/97 (80.41%), Query Frame = 1

Query: 1276 GSEIEKEKRQ--DTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRE 1560
            G  ++KE RQ  DTCEFCGKVF+NCSNLTVHRRSHTGEKPY+C LC YACAQSSKLTRHMKTHGR G     C++C  PF V +TLEKHMRKC + +
Sbjct: 1016 GPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQ 1112

HSP 2 Score: 64.6994 bits (156), Expect = 2.131e-10
Identity = 24/50 (48.00%), Postives = 35/50 (70.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +C +C K FR  +NL +H+R+HTGEKPY+C  C + C+   KL +HM+ H
Sbjct:  718 SCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVH 767

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Zebrafish
Match: bcl11ab (BAF chromatin remodeling complex subunit BCL11A b [Source:ZFIN;Acc:ZDB-GENE-061009-4])

HSP 1 Score: 138.272 bits (347), Expect = 8.131e-34
Identity = 61/83 (73.49%), Postives = 69/83 (83.13%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCEFCGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C+ C  PF V +TLEKHM+K
Sbjct:  680 RRSDTCEFCGKVFKNCSNLTVHRRSHTGERPYKCELCSYACAQSSKLTRHMKTHGQTGKDVYKCEICHMPFSVYSTLEKHMKK 762

HSP 2 Score: 90.1225 bits (222), Expect = 2.731e-18
Identity = 38/50 (76.00%), Postives = 43/50 (86.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +CEFCGK F+  SNL VHRRSHTGEKPY+CHLC +AC Q+SKL RHMKTH
Sbjct:  335 SCEFCGKSFKFQSNLIVHRRSHTGEKPYKCHLCNHACTQASKLKRHMKTH 384

HSP 3 Score: 53.5286 bits (127), Expect = 5.604e-7
Identity = 43/169 (25.44%), Postives = 62/169 (36.69%), Query Frame = 1

Query:  364 MSRRKQIQPQQL----------------------FIESNSVSSDIDYITCGECQKTFEFENIMVFLTHKMFHMKG----------------------------SITDSPGKIGLLSSRNYLPTSILSKKE--SNNNYKECIQCCHCWKFFGSAWKLLQHVQRNHKISVY 714
            MSRRKQ +PQ L                        E ++   D D +TCG+C+  F   +I+VF+ HK    +G                            ++  SP     L+S    P  +  K+E  S  +      C  C + F +AW LLQH Q  H   +Y
Sbjct:    1 MSRRKQGKPQHLSKREFSPEPVTADIPEDGESNPGSEPSTPKGDQDLLTCGQCRSRFPLADILVFIEHKRRQCQGRLCMDKSSDLPPSPPPAGLRRACIPVEVAVQVSPHGEERLAS---TPHGLRPKQENLSEKDEPSSYTCTTCKQPFSTAWFLLQHAQNTHGFRIY 166

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Zebrafish
Match: bcl11aa (BAF chromatin remodeling complex subunit BCL11A a [Source:ZFIN;Acc:ZDB-GENE-060421-4643])

HSP 1 Score: 137.502 bits (345), Expect = 1.446e-33
Identity = 61/83 (73.49%), Postives = 69/83 (83.13%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCEFCGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C+ C  PF V +TLEKHM+K
Sbjct:  733 RRTDTCEFCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKDVYKCEICQMPFSVYSTLEKHMKK 815

HSP 2 Score: 90.8929 bits (224), Expect = 1.561e-18
Identity = 38/50 (76.00%), Postives = 43/50 (86.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +CEFCGK F+  SNL VHRRSHTGEKPY+CHLC +AC Q+SKL RHMKTH
Sbjct:  357 SCEFCGKTFKFQSNLIVHRRSHTGEKPYKCHLCDHACTQASKLKRHMKTH 406

HSP 3 Score: 53.5286 bits (127), Expect = 5.983e-7
Identity = 43/170 (25.29%), Postives = 65/170 (38.24%), Query Frame = 1

Query:  364 MSRRKQIQPQQL----------------------FIESNSVSSDIDYITCGECQKTFEFENIMVFLTHKMFHMKGSI-------------------TDSPGKIGL-----------LSSRNYLPTSI-LSKKESNNNYKECIQCCHCWKFFGSAWKLLQHVQRNHKISVY 714
            MSRRKQ +PQ L                       +   +   D D +TCG+CQ  F   +I++F+ HK     G++                     +P ++G+            SSR   P    ++ K+  ++Y     C  C + F SAW LLQH Q  H   +Y
Sbjct:    1 MSRRKQGKPQHLSKRDFSPEPLSAVVSEERQEQRGLVQVAPEGDQDLLTCGQCQMNFPLGDILIFIEHKRKQCNGTLCMDKAVDKPPSPSHGELRRASNPVEVGVQVTPEDDDCLSTSSRGICPKQENITGKDEPSSYT----CTTCKQPFSSAWFLLQHAQNTHGFRIY 166

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Zebrafish
Match: bcl11ba (BAF chromatin remodeling complex subunit BCL11B a [Source:ZFIN;Acc:ZDB-GENE-061207-62])

HSP 1 Score: 137.502 bits (345), Expect = 1.781e-33
Identity = 60/86 (69.77%), Postives = 70/86 (81.40%), Query Frame = 1

Query: 1288 EKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            ++ +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K
Sbjct:  710 KESRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQLGKEVYRCDICQMPFSVYSTLEKHMKK 795

HSP 2 Score: 92.4337 bits (228), Expect = 4.859e-19
Identity = 41/78 (52.56%), Postives = 54/78 (69.23%), Query Frame = 1

Query: 1225 KTEILSAYEISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            K+  LS   +  +  N  +  + + +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  342 KSPFLSTPPLPPMPPNSTTPPQTQGKSKSCEFCGKTFKFQSNLVVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 419

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Zebrafish
Match: znf296 (zinc finger protein 296 [Source:ZFIN;Acc:ZDB-GENE-050419-201])

HSP 1 Score: 136.346 bits (342), Expect = 2.263e-33
Identity = 63/106 (59.43%), Postives = 77/106 (72.64%), Query Frame = 1

Query: 1231 EILSAYEISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRS-MHCKYCGTPFIVATTLEKHMRK 1545
            EI+  ++  N      + + K+K+++ CEFCGK FRN SNLTVHRRSHTGE+PYRC LC YACAQSSKLTRHMKTHG  G R+   C+ C  PF V  TLEKH++K
Sbjct:  445 EIVQDWQRENERRQVTNGMGKKKKEEACEFCGKCFRNSSNLTVHRRSHTGERPYRCGLCSYACAQSSKLTRHMKTHGARGTRAPFQCQLCSVPFTVYATLEKHLKK 550

HSP 2 Score: 61.6178 bits (148), Expect = 1.682e-9
Identity = 24/52 (46.15%), Postives = 37/52 (71.15%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGR 1464
            +CE CG+ F++  +L+ HRR+H  ++PY C LCQ   +QS +L RHM++H R
Sbjct:  261 SCEMCGQGFQSLRSLSAHRRTHACDRPYHCGLCQLTFSQSGELARHMRSHRR 312

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Zebrafish
Match: im:7142702 (im:7142702 [Source:ZFIN;Acc:ZDB-GENE-050411-48])

HSP 1 Score: 133.65 bits (335), Expect = 2.525e-32
Identity = 59/86 (68.60%), Postives = 70/86 (81.40%), Query Frame = 1

Query: 1288 EKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            ++ +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKH++K
Sbjct:  690 KESRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCDLCSYACAQSSKLTRHMKTHGQFGKEVYRCDICHMPFSVYSTLEKHVKK 775

HSP 2 Score: 92.0485 bits (227), Expect = 6.697e-19
Identity = 39/63 (61.90%), Postives = 49/63 (77.78%), Query Frame = 1

Query: 1270 NCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            N  S + +  +  +CEFCGK F+  SNL VHRRSHTGE+PY+CHLC +AC+Q+SKL RHMKTH
Sbjct:  355 NSSSPLNQVGKAKSCEFCGKTFKFQSNLIVHRRSHTGERPYKCHLCDHACSQASKLKRHMKTH 417

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Xenopus
Match: aqp7 (aquaporin 7 [Source:Xenbase;Acc:XB-GENE-484060])

HSP 1 Score: 138.658 bits (348), Expect = 1.016e-33
Identity = 61/83 (73.49%), Postives = 68/83 (81.93%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCEFCGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K
Sbjct:  728 RRSDTCEFCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKK 810

HSP 2 Score: 89.7373 bits (221), Expect = 5.416e-18
Identity = 37/57 (64.91%), Postives = 46/57 (80.70%), Query Frame = 1

Query: 1288 EKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            + + +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  372 QTQAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 428

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Xenopus
Match: aqp7 (aquaporin 7 [Source:Xenbase;Acc:XB-GENE-484060])

HSP 1 Score: 116.701 bits (291), Expect = 1.261e-26
Identity = 52/71 (73.24%), Postives = 59/71 (83.10%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPF 1509
            +R DTCEFCGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G +    +  G PF
Sbjct:  706 RRSDTCEFCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGGQQ---RTKGYPF 773

HSP 2 Score: 90.1225 bits (222), Expect = 3.493e-18
Identity = 37/57 (64.91%), Postives = 46/57 (80.70%), Query Frame = 1

Query: 1288 EKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            + + +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  350 QTQAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 406

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Xenopus
Match: aqp7 (aquaporin 7 [Source:Xenbase;Acc:XB-GENE-484060])

HSP 1 Score: 115.931 bits (289), Expect = 1.906e-26
Identity = 49/58 (84.48%), Postives = 54/58 (93.10%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREG 1470
            +R DTCEFCGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G
Sbjct:  728 RRSDTCEFCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIG 785

HSP 2 Score: 89.7373 bits (221), Expect = 4.223e-18
Identity = 37/57 (64.91%), Postives = 46/57 (80.70%), Query Frame = 1

Query: 1288 EKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            + + +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  372 QTQAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 428

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Xenopus
Match: bcl11a (BCL11A, BAF complex component [Source:NCBI gene;Acc:780114])

HSP 1 Score: 114.005 bits (284), Expect = 9.036e-26
Identity = 47/56 (83.93%), Postives = 53/56 (94.64%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGR 1464
            KR DTCE+CGK+F+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+
Sbjct:  649 KRSDTCEYCGKIFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQ 704

HSP 2 Score: 88.5817 bits (218), Expect = 8.974e-18
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C+LC +AC Q+SKL RHMKTH
Sbjct:  290 KSKSCEFCGKTFKFQSNLVVHRRSHTGEKPYKCNLCDHACTQASKLKRHMKTH 342

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Xenopus
Match: bcl11a (BCL11A, BAF complex component [Source:NCBI gene;Acc:780114])

HSP 1 Score: 113.62 bits (283), Expect = 1.142e-25
Identity = 47/56 (83.93%), Postives = 53/56 (94.64%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGR 1464
            KR DTCE+CGK+F+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+
Sbjct:  701 KRSDTCEYCGKIFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQ 756

HSP 2 Score: 88.1965 bits (217), Expect = 1.345e-17
Identity = 37/50 (74.00%), Postives = 43/50 (86.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +CEFCGK F+  SNL VHRRSHTGEKPY+C+LC +AC Q+SKL RHMKTH
Sbjct:  345 SCEFCGKTFKFQSNLVVHRRSHTGEKPYKCNLCDHACTQASKLKRHMKTH 394

HSP 3 Score: 55.8398 bits (133), Expect = 1.713e-7
Identity = 43/164 (26.22%), Postives = 61/164 (37.20%), Query Frame = 1

Query:  364 MSRRKQIQPQQL--------FIES------------NSVSSDIDYITCGECQKTFEFENIMVFLTHKMFHMKGSI--------TDSPGKIGLLSSRNYLPTSILSKKESNN-------------------NYKECIQCCHCWKFFGSAWKLLQHVQRNHKISVY 714
            MSRRKQ +PQ L         +E+             +   D D +TCG+CQ  F   +I++F+ HK     GS+          SP    L  + N +   I    E ++                   +      C  C + F SAW LLQH Q  H   +Y
Sbjct:    1 MSRRKQGKPQHLSKREYSPEPVEAILTDDEPDNSTLGAGEGDHDLLTCGQCQMNFPLGDILIFIEHKRKQCNGSLCLEKAGDKPPSPTPSELKKASNPVEVGIQVTPEDDDCLSTSSRGICPKQENAAGKDEPSSYTCTTCKQPFSSAWFLLQHAQNTHGFRIY 164

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Mouse
Match: Bcl11a (B cell CLL/lymphoma 11A (zinc finger protein) [Source:MGI Symbol;Acc:MGI:106190])

HSP 1 Score: 139.428 bits (350), Expect = 4.194e-34
Identity = 65/99 (65.66%), Postives = 75/99 (75.76%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNSFGT 1593
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C+ C  PF V +TLEKHM+K     S+R L N   T
Sbjct:  739 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKDVYKCEICKMPFSVYSTLEKHMKKW---HSDRVLNNDIKT 834

HSP 2 Score: 88.5817 bits (218), Expect = 8.958e-18
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C+LC +AC Q+SKL RHMKTH
Sbjct:  375 KSKSCEFCGKTFKFQSNLVVHRRSHTGEKPYKCNLCDHACTQASKLKRHMKTH 427

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Mouse
Match: Bcl11b (B cell leukemia/lymphoma 11B [Source:MGI Symbol;Acc:MGI:1929913])

HSP 1 Score: 137.502 bits (345), Expect = 1.288e-33
Identity = 60/84 (71.43%), Postives = 68/84 (80.95%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKC 1548
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K 
Sbjct:  589 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKKW 672

HSP 2 Score: 89.3521 bits (220), Expect = 3.888e-18
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  230 KSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 282

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Mouse
Match: Bcl11b (B cell leukemia/lymphoma 11B [Source:MGI Symbol;Acc:MGI:1929913])

HSP 1 Score: 137.502 bits (345), Expect = 1.641e-33
Identity = 60/83 (72.29%), Postives = 68/83 (81.93%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K
Sbjct:  711 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKK 793

HSP 2 Score: 89.3521 bits (220), Expect = 4.110e-18
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  352 KSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 404

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Mouse
Match: Bcl11b (B cell leukemia/lymphoma 11B [Source:MGI Symbol;Acc:MGI:1929913])

HSP 1 Score: 137.502 bits (345), Expect = 2.166e-33
Identity = 60/83 (72.29%), Postives = 68/83 (81.93%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K
Sbjct:  783 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKK 865

HSP 2 Score: 89.3521 bits (220), Expect = 4.886e-18
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  424 KSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 476

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Mouse
Match: Zfp296 (zinc finger protein 296 [Source:MGI Symbol;Acc:MGI:1926956])

HSP 1 Score: 108.612 bits (270), Expect = 7.591e-25
Identity = 48/78 (61.54%), Postives = 58/78 (74.36%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            CEFCGK F N SNLTVHRRSHTGE+PY C  C YACAQSSKL RH +THG    +++ C +C  PF +  TL+KH+R+
Sbjct:  362 CEFCGKSFTNSSNLTVHRRSHTGERPYTCDQCPYACAQSSKLNRHRRTHGLGTGKTVKCPHCLVPFGLQATLDKHLRQ 439

HSP 2 Score: 75.0998 bits (183), Expect = 7.455e-14
Identity = 34/54 (62.96%), Postives = 38/54 (70.37%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +R  TC+ C K   + SNL VH RSHTGE+PY C  C YACAQSSKL RH KTH
Sbjct:  209 RRSPTCDVCKKTLSSFSNLKVHMRSHTGERPYSCDQCSYACAQSSKLNRHKKTH 262

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BLAST of B-cell lymphoma/leukemia 11B vs. UniProt/SwissProt
Match: sp|Q9H165|BC11A_HUMAN (B-cell lymphoma/leukemia 11A OS=Homo sapiens OX=9606 GN=BCL11A PE=1 SV=2)

HSP 1 Score: 139.428 bits (350), Expect = 2.829e-33
Identity = 65/99 (65.66%), Postives = 75/99 (75.76%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNSFGT 1593
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C+ C  PF V +TLEKHM+K     S+R L N   T
Sbjct:  739 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKDVYKCEICKMPFSVYSTLEKHMKKW---HSDRVLNNDIKT 834

HSP 2 Score: 88.5817 bits (218), Expect = 6.212e-17
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C+LC +AC Q+SKL RHMKTH
Sbjct:  375 KSKSCEFCGKTFKFQSNLVVHRRSHTGEKPYKCNLCDHACTQASKLKRHMKTH 427

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. UniProt/SwissProt
Match: sp|Q9C0K0|BC11B_HUMAN (B-cell lymphoma/leukemia 11B OS=Homo sapiens OX=9606 GN=BCL11B PE=1 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 1.258e-32
Identity = 60/83 (72.29%), Postives = 68/83 (81.93%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K
Sbjct:  793 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKK 875

HSP 2 Score: 89.3521 bits (220), Expect = 3.239e-17
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  425 KSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 477

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. UniProt/SwissProt
Match: sp|Q99PV8|BC11B_MOUSE (B-cell lymphoma/leukemia 11B OS=Mus musculus OX=10090 GN=Bcl11b PE=1 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 1.515e-32
Identity = 60/83 (72.29%), Postives = 68/83 (81.93%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K
Sbjct:  783 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKK 865

HSP 2 Score: 89.3521 bits (220), Expect = 3.418e-17
Identity = 37/53 (69.81%), Postives = 44/53 (83.02%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  424 KSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 476

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. UniProt/SwissProt
Match: sp|E9Q6W4|ZN296_MOUSE (Zinc finger protein 296 OS=Mus musculus OX=10090 GN=Znf296 PE=1 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 5.310e-24
Identity = 48/78 (61.54%), Postives = 58/78 (74.36%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            CEFCGK F N SNLTVHRRSHTGE+PY C  C YACAQSSKL RH +THG    +++ C +C  PF +  TL+KH+R+
Sbjct:  362 CEFCGKSFTNSSNLTVHRRSHTGERPYTCDQCPYACAQSSKLNRHRRTHGLGTGKTVKCPHCLVPFGLQATLDKHLRQ 439

HSP 2 Score: 75.0998 bits (183), Expect = 5.215e-13
Identity = 34/54 (62.96%), Postives = 38/54 (70.37%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +R  TC+ C K   + SNL VH RSHTGE+PY C  C YACAQSSKL RH KTH
Sbjct:  209 RRSPTCDVCKKTLSSFSNLKVHMRSHTGERPYSCDQCSYACAQSSKLNRHKKTH 262

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. UniProt/SwissProt
Match: sp|Q8WUU4|ZN296_HUMAN (Zinc finger protein 296 OS=Homo sapiens OX=9606 GN=ZNF296 PE=1 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 9.012e-23
Identity = 48/80 (60.00%), Postives = 56/80 (70.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHG-REGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +CEFCGK F N SNLTVHRRSHTGE+PY C  C YACAQSSKL RH + HG   G     C +C  PF +  TL+KH+R+
Sbjct:  387 SCEFCGKHFTNSSNLTVHRRSHTGERPYTCEFCNYACAQSSKLNRHRRMHGMTPGSTRFECPHCHVPFGLRATLDKHLRQ 466

HSP 2 Score: 74.7146 bits (182), Expect = 7.219e-13
Identity = 34/54 (62.96%), Postives = 37/54 (68.52%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +R  TC  C K   + SNL VH RSHTGE+PY C  C YACAQSSKL RH KTH
Sbjct:  228 RRSPTCPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPYACAQSSKLNRHKKTH 281

HSP 3 Score: 55.4546 bits (132), Expect = 9.202e-7
Identity = 32/98 (32.65%), Postives = 45/98 (45.92%), Query Frame = 1

Query:  433 DYITCGECQKTFEFENIMVFLTHKMFHMKGSITDSPGKIGLLSSRNYLPTSILSKKESNNNYKECIQCCHCWKFFGSAWKLLQHVQRNHKISVYKIHS 726
            D +TCG C +TF  E I  F+ HK    +  +   P + G  S R  L               + + C  C K F  AWKLL+H Q +H +S+Y+  S
Sbjct:  110 DLLTCGRCLQTFPLEAITAFMDHKKLGCQ--LFRGPSR-GQGSEREEL---------------KALSCLRCGKQFTVAWKLLRHAQWDHGLSIYQTES 189

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BLAST of B-cell lymphoma/leukemia 11B vs. TrEMBL
Match: V4B224 (Uncharacterized protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_139415 PE=4 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 1.555e-41
Identity = 122/328 (37.20%), Postives = 154/328 (46.95%), Query Frame = 1

Query:  634 CCHCWKFFGSAWKLLQHVQRNHKISVYKIH--------SPRLKVLRKXXXXXXXXXXXXXXXXXXKFALSTPINGTENQDSDHQKPIMEQSKYNLSVKDDNDNICDS----QSNIITCDSSIIDGNSSLKTNLSYFFEKANTGTGSV-NNMMIEENNYMPANNTDAFSMSSLLSSPIVKGIKFDSTPNPNTTLSLIADQTNSVRSDETKLKTEILSAYEISNVAFNCGSEIEKEK-RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFL 1575
            C  C   F SAWKL+QH Q+ H I ++ +         SPRL + ++                       TP        S H+  +  +S  N+S K  +   C       SN+I    S   G    K  L      A T    +  +M    NN  P +     S  S  S P      F   P+ N    L A Q ++++S    L     S   +S+   N  S I ++  R DTCE+CGK+FRNCSNLTVHRRSHTGEKPY+C LC YACAQSSKLTRH +THGR G     CK+C  PF VA+TLEKHMRKC      R L
Sbjct:    1 CDTCKAPFNSAWKLVQHAQKEHGIKIFTLPMRPDLSTPSPRLNLEQR-----------------------TPPTSGHESPSTHE--MSSESGSNMSPKLKSCEFCGKSFRFPSNLIVHRRSHT-GEKPFKCPLC---PHACTQQSKLKRHMKTHLNNKSPMSANSHGSNPSTFSPPFGVNHDFRREPHLNG-FGLAASQDSALKS--VGLPKPGPS---VSHSPSNGPSPIPRKSLRNDTCEYCGKIFRNCSNLTVHRRSHTGEKPYKCELCNYACAQSSKLTRHKRTHGRMGKDVYRCKFCAMPFSVASTLEKHMRKCVDNRQARLL 293

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. TrEMBL
Match: A0A0R3U2B3 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS583 PE=4 SV=1)

HSP 1 Score: 156.377 bits (394), Expect = 4.540e-40
Identity = 69/98 (70.41%), Postives = 83/98 (84.69%), Query Frame = 1

Query: 1288 EKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGN 1581
            ++EKR DTCEFCGKVF+NCSNLTVHRRSHTG+KPY+C LC YACAQSSKLTRHM TH ++G  S++C+YC TPFIVA+TLEKH R+C L+  +  L N
Sbjct:  130 QREKRSDTCEFCGKVFKNCSNLTVHRRSHTGDKPYKCALCPYACAQSSKLTRHMNTHKKKGKSSLYCRYCFTPFIVASTLEKHKRRCSLKRKHSDLLN 227

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BLAST of B-cell lymphoma/leukemia 11B vs. TrEMBL
Match: A0A5K3EUQ7 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 159.458 bits (402), Expect = 7.663e-40
Identity = 67/90 (74.44%), Postives = 79/90 (87.78%), Query Frame = 1

Query: 1288 EKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLR 1557
            ++EKR DTCEFCGKVF+NCSNLTVHRRSHTG+KPY+C LC YACAQSSKLTRHM TH ++G  S++C+YC TPFIVA+TLEKH R+C  R
Sbjct:  130 QREKRSDTCEFCGKVFKNCSNLTVHRRSHTGDKPYKCALCPYACAQSSKLTRHMNTHKKKGKSSLYCRYCFTPFIVASTLEKHKRRCSAR 219

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. TrEMBL
Match: K1PWX7 (B-cell lymphoma/leukemia 11B OS=Crassostrea gigas OX=29159 GN=CGI_10011779 PE=4 SV=1)

HSP 1 Score: 154.451 bits (389), Expect = 1.018e-39
Identity = 75/116 (64.66%), Postives = 82/116 (70.69%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNSFGTGSSGESEISCDSRMDNSI 1647
            R DTCEFCGKVF+NCSNLTVHRRSHTGEKPY+C LC YACAQSSKLTRHMKTHGR G     CK+CG PF VA+TLEKHMRKC  +          G+G  G      DS   NS+
Sbjct:   86 RNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCNYACAQSSKLTRHMKTHGRIGKDVYRCKFCGMPFSVASTLEKHMRKCVEK----------GSGMQGLGRQDMDSDNSNSV 191

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. TrEMBL
Match: A0A3S1A0R7 (Uncharacterized protein (Fragment) OS=Elysia chlorotica OX=188477 GN=EGW08_012434 PE=4 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 7.641e-39
Identity = 71/105 (67.62%), Postives = 78/105 (74.29%), Query Frame = 1

Query: 1288 EKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNSFGTGSS 1602
            E  KR DTCE+CGKVF+NCSNLTVHRRSHTGEKPY+C LC YACAQSSKLTRHMKTHGR G     CK+C  PF V +TLEKHMRKC    +   +G   G  SS
Sbjct:   21 EASKRNDTCEYCGKVFKNCSNLTVHRRSHTGEKPYKCSLCSYACAQSSKLTRHMKTHGRLGKDVYTCKFCNMPFSVPSTLEKHMRKCVENRNAHLMGQDAGDLSS 125

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BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Cavefish
Match: znf296 (zinc finger protein 296 [Source:ZFIN;Acc:ZDB-GENE-050419-201])

HSP 1 Score: 138.658 bits (348), Expect = 2.625e-34
Identity = 61/86 (70.93%), Postives = 70/86 (81.40%), Query Frame = 1

Query: 1291 KEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRS-MHCKYCGTPFIVATTLEKHMRK 1545
            ++KR++ CEFCGK FRN SNLTVHRRSHTGE+PYRC LC YACAQSSKLTRHMKTHG  G R+  HC+ C  PF V  TLEKH++K
Sbjct:  479 RKKREEACEFCGKRFRNSSNLTVHRRSHTGERPYRCGLCSYACAQSSKLTRHMKTHGARGSRAPFHCQLCSVPFTVYATLEKHLKK 564

HSP 2 Score: 64.6994 bits (156), Expect = 1.858e-10
Identity = 28/65 (43.08%), Postives = 41/65 (63.08%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGT 1503
            +CE CG+ F++  +L+ HRR+H  E+PY C  CQ   AQS +L RHM++H R    S+  +  GT
Sbjct:  268 SCEICGQSFQSLRSLSAHRRTHACERPYHCGRCQLTFAQSGELARHMRSH-RRAAASLQAQEAGT 331

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Cavefish
Match: BCL11B (BAF chromatin remodeling complex subunit BCL11B [Source:HGNC Symbol;Acc:HGNC:13222])

HSP 1 Score: 137.887 bits (346), Expect = 1.057e-33
Identity = 60/84 (71.43%), Postives = 68/84 (80.95%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKC 1548
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K 
Sbjct:  712 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQLGKEVYRCDICQMPFSVYSTLEKHMKKW 795

HSP 2 Score: 89.7373 bits (221), Expect = 2.987e-18
Identity = 37/57 (64.91%), Postives = 46/57 (80.70%), Query Frame = 1

Query: 1288 EKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            + + +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  361 QTQDKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 417

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Cavefish
Match: bcl11aa (BAF chromatin remodeling complex subunit BCL11A [Source:NCBI gene;Acc:103026335])

HSP 1 Score: 137.117 bits (344), Expect = 1.620e-33
Identity = 60/83 (72.29%), Postives = 69/83 (83.13%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C+ C  PF V +TLEKHM+K
Sbjct:  722 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKDVYKCEICQMPFSVYSTLEKHMKK 804

HSP 2 Score: 90.8929 bits (224), Expect = 1.109e-18
Identity = 38/50 (76.00%), Postives = 42/50 (84.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
             CEFCGK F+  SNL VHRRSHTGEKPY+CHLC +AC Q+SKL RHMKTH
Sbjct:  357 ACEFCGKTFKFQSNLIVHRRSHTGEKPYKCHLCDHACTQASKLKRHMKTH 406

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Cavefish
Match: im:7142702 (B-cell lymphoma/leukemia 11A-like [Source:NCBI gene;Acc:103027528])

HSP 1 Score: 135.576 bits (340), Expect = 6.371e-33
Identity = 60/83 (72.29%), Postives = 68/83 (81.93%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K
Sbjct:  694 RRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCDLCSYACAQSSKLTRHMKTHGQFGKEVYRCDICHMPFSVYSTLEKHMKK 776

HSP 2 Score: 90.1225 bits (222), Expect = 1.897e-18
Identity = 37/50 (74.00%), Postives = 44/50 (88.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +CEFCGK F+  SNL VHRRSHTGE+PY+CHLC +AC+Q+SKL RHMKTH
Sbjct:  364 SCEFCGKTFKFQSNLIVHRRSHTGERPYKCHLCDHACSQASKLKRHMKTH 413

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Cavefish
Match: ENSAMXT00000055377.1 (zinc finger protein 692 [Source:NCBI gene;Acc:103021608])

HSP 1 Score: 78.9518 bits (193), Expect = 6.773e-15
Identity = 33/76 (43.42%), Postives = 44/76 (57.89%), Query Frame = 1

Query: 1282 EIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPF 1509
            ++  ++R   CEFC + FR  SNL++HRR HTGEKP +C +C Y C Q + L  HM+ H  E      C  CG  F
Sbjct:  691 KLHSDQRDYICEFCARAFRTSSNLSIHRRIHTGEKPLQCEVCGYTCRQKASLNWHMRKHDAESSYQFPCDICGRRF 766

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007831.1 (pep scaffold:Pmarinus_7.0:GL477655:47469:47963:1 gene:ENSPMAG00000007084.1 transcript:ENSPMAT00000007831.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.4698 bits (158), Expect = 2.098e-13
Identity = 32/76 (42.11%), Postives = 45/76 (59.21%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHM 1539
            C  CGK F   S+L  H+R+HTGEKP++C +C+ A +QSS L +H +TH  E  +   C  C   F  ++ L KH 
Sbjct:   34 CPLCGKAFAKSSDLQSHQRTHTGEKPFKCSVCEKAFSQSSNLKKHQRTHTGE--KPFKCTVCEKAFTESSPLRKHQ 107

HSP 2 Score: 55.0694 bits (131), Expect = 9.265e-10
Identity = 33/77 (42.86%), Postives = 42/77 (54.55%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  C K F   S LT+H R+HT  KP+RC LC  A A+SS L  H +TH  E  +   C  C   F  ++ L+KH R
Sbjct:    8 CTVCEKAFAQSSYLTIHLRTHT--KPFRCPLCGKAFAKSSDLQSHQRTHTGE--KPFKCSVCEKAFSQSSNLKKHQR 80

HSP 3 Score: 48.521 bits (114), Expect = 1.874e-7
Identity = 24/56 (42.86%), Postives = 34/56 (60.71%), Query Frame = 1

Query: 1375 TGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            TGEKP++C +C+ A AQSS LT H++TH     +   C  CG  F  ++ L+ H R
Sbjct:    1 TGEKPFKCTVCEKAFAQSSYLTIHLRTHT----KPFRCPLCGKAFAKSSDLQSHQR 52

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006856.1 (pep scaffold:Pmarinus_7.0:GL476534:515915:516469:1 gene:ENSPMAG00000006196.1 transcript:ENSPMAT00000006856.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.855 bits (159), Expect = 3.449e-13
Identity = 35/80 (43.75%), Postives = 42/80 (52.50%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKH 1536
            +R  TC  CGK F    NL +H R HTGEKPY C+ C  A ++S  L +H  TH  E  R   C  CG  F  A  L+ H
Sbjct:   27 ERPFTCALCGKAFGTAWNLRIHERKHTGEKPYECNACGRAFSESGHLDKHRATHAAE--RPFKCDTCGRAFAQARYLKSH 104

HSP 2 Score: 53.5286 bits (127), Expect = 5.844e-9
Identity = 31/101 (30.69%), Postives = 46/101 (45.54%), Query Frame = 1

Query: 1252 ISNVAFNCGSEIEKEKRQDT------CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKH 1536
            +   AF     +   +R+ T      C  CG+ F    +L  HR +H  E+P++C  C  A AQ+  L  H  TH  +  R   C  CG  F +A  L++H
Sbjct:   34 LCGKAFGTAWNLRIHERKHTGEKPYECNACGRAFSESGHLDKHRATHAAERPFKCDTCGRAFAQARYLKSHRATHAAD--RPFECGACGKTFTLARYLDRH 132

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008278.1 (pep scaffold:Pmarinus_7.0:GL477891:43090:46668:-1 gene:ENSPMAG00000007492.1 transcript:ENSPMAT00000008278.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.4698 bits (158), Expect = 7.301e-13
Identity = 35/87 (40.23%), Postives = 45/87 (51.72%), Query Frame = 1

Query: 1285 IEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +  ++R   CE CG  F++  NL +H R HTGEKP +C LC Y C Q + L  HM+ H  E   S  C  CG  F  +  L  H  K
Sbjct:   68 LHSDERNFVCETCGASFKSKKNLLIHLRIHTGEKPLQCELCGYRCRQKASLNWHMRKHNIELSFSFACDLCGKRFEKSDNLRCHQLK 154

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004838.1 (pep scaffold:Pmarinus_7.0:GL495265:3215:3667:-1 gene:ENSPMAG00000004400.1 transcript:ENSPMAT00000004838.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.3142 bits (155), Expect = 7.789e-13
Identity = 32/77 (41.56%), Postives = 41/77 (53.25%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C+ CG+ F   S L  HRR HTGE+PY C +C  A AQ   L  H +TH   G R   C  CG  F + + ++ H R
Sbjct:   47 CDACGRAFARRSGLEYHRRVHTGERPYGCEVCGRAFAQYGNLKVHRRTH--TGERPHRCDVCGRSFTLCSNMKTHQR 121

HSP 2 Score: 56.225 bits (134), Expect = 5.153e-10
Identity = 29/71 (40.85%), Postives = 39/71 (54.93%), Query Frame = 1

Query: 1264 AFNCGSEIEKEKRQDT------CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            AF   S +E  +R  T      CE CG+ F    NL VHRR+HTGE+P+RC +C  +    S +  H +TH
Sbjct:   53 AFARRSGLEYHRRVHTGERPYGCEVCGRAFAQYGNLKVHRRTHTGERPHRCDVCGRSFTLCSNMKTHQRTH 123

HSP 3 Score: 51.9878 bits (123), Expect = 1.636e-8
Identity = 31/86 (36.05%), Postives = 42/86 (48.84%), Query Frame = 1

Query: 1291 KEKRQDTCE--FCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            + +R   C+  FC + F   + L  H R+H GEKP+RC  C  A A+ S L  H + H   G R   C+ CG  F     L+ H R
Sbjct:   10 RPERSRPCKRSFCERRFEEPAYLKRHERTHAGEKPHRCDACGRAFARRSGLEYHRRVH--TGERPYGCEVCGRAFAQYGNLKVHRR 93

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BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004611.1 (pep scaffold:Pmarinus_7.0:GL476524:167506:168579:-1 gene:ENSPMAG00000004189.1 transcript:ENSPMAT00000004611.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 67.0106 bits (162), Expect = 1.112e-12
Identity = 45/151 (29.80%), Postives = 66/151 (43.71%), Query Frame = 1

Query: 1147 STPNPNTTLSLIADQT----------NSVRSDETKLKTEILSAYEISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNR 1569
            S P P   +  + D+T           +  SD  +   E+         A      +  +     C+ CG ++   + L  H RSHTGE+P++C LC  A      LT H+K H  E  R+  C  CG  F+ A TL +H RK CL++  R
Sbjct:   31 SGPPPKPFVCDVCDKTFVSSNYLMEHKACHSDVKRYVCEVCGKSYKHKPALRAHKRLHSDNNPYICKECGNIYARNAQLVAHLRSHTGERPFQCELCGKAFIHRCSLTMHLKRHSGE--RNFVCTDCGMAFLDAYTLNEHRRKQCLQKHQR 179

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BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Yeast
Match: ZAP1 (Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592])

HSP 1 Score: 64.6994 bits (156), Expect = 2.437e-11
Identity = 31/77 (40.26%), Postives = 46/77 (59.74%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C+ C + F +   L  H R+H+GEKPY+CH+C    A SS L  H++TH  E  + + CK CG  F  ++ L KH++
Sbjct:  770 CKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGE--KPLQCKICGKRFNESSNLSKHIK 844

HSP 2 Score: 53.9138 bits (128), Expect = 5.927e-8
Identity = 30/82 (36.59%), Postives = 41/82 (50.00%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLR 1557
            C  C K F   S+L +H R+HTGEKP +C +C     +SS L++H+KTH ++      C  C   F     L     KC L 
Sbjct:  798 CHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTHQKK----YKCSDCSKSFDDLGKLNSQKVKCALE 875

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Yeast
Match: AZF1 (Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005639])

HSP 1 Score: 56.6102 bits (135), Expect = 7.708e-9
Identity = 27/80 (33.75%), Postives = 38/80 (47.50%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKY--CGTPFIVATTLEKHMRK 1545
            C++CGK F    NL  H R HTGEKPY C +C    ++   L  H+ TH +   +   CK   C   F     ++ H  +
Sbjct:  623 CDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQK--LKPFVCKLENCNKTFTQLGNMKAHQNR 700

HSP 2 Score: 50.0618 bits (118), Expect = 8.261e-7
Identity = 25/88 (28.41%), Postives = 39/88 (44.32%), Query Frame = 1

Query: 1276 GSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHM 1539
            G++  +  ++  C +C ++F   ++L VH RSH G KP+ C  C     Q   L  H + H   G +   C  C   F     L  H+
Sbjct:  583 GTQNTRAVKKHECPYCHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLH--TGEKPYSCDICDKKFSRKGNLAAHL 668

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BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Yeast
Match: MSN2 (Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes; relative distribution to nucleus increases upon DNA replication stress [Source:SGD;Acc:S000004640])

HSP 1 Score: 53.5286 bits (127), Expect = 5.974e-8
Identity = 23/62 (37.10%), Postives = 37/62 (59.68%), Query Frame = 1

Query: 1288 EKEKRQDTCEFCGKVFRNCSNLTVHRRS-HTGEKPYRCHLCQYACAQSSKLTRHMKTHGREG 1470
            E E++   C  C K F+   +L  H RS H+ E+P+ CH+C    ++S  L++H+KTH + G
Sbjct:  641 ELEEKPFHCHICPKSFKRSEHLKRHVRSVHSNERPFACHICDKKFSRSDNLSQHIKTHKKHG 702

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Yeast
Match: COM2 (Transcription factor that binds IME1 Upstream Activation Signal (UAS)ru; COM2 transcription is regulated by Haa1p, Sok2p and Zap1p transcriptional activators; may bind the IME1 promoter under all growth conditions to negatively regulate its transcription in the absence of a positive regulator that binds more effectively; repressor activity may depend on phosphorylation by PKA; C. albicans homolog (MNL1) plays a role in adaptation to stress [Source:SGD;Acc:S000000932])

HSP 1 Score: 51.2174 bits (121), Expect = 3.122e-7
Identity = 25/62 (40.32%), Postives = 35/62 (56.45%), Query Frame = 1

Query: 1279 SEIEKEKRQDTCEFCGKVFRNCSNLTVHRRS-HTGEKPYRCHLCQYACAQSSKLTRHMKTHG 1461
            S I    +Q  CEFC + F+   +L  H RS H  EKP+ CH+C    ++S  L +H+KTH 
Sbjct:  380 SLIPDASKQFGCEFCDRRFKRQEHLKRHVRSLHMCEKPFTCHICNKNFSRSDNLNQHVKTHA 441

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BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Yeast
Match: YGR067C_mRNA (Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p [Source:SGD;Acc:S000003299])

HSP 1 Score: 50.8322 bits (120), Expect = 4.641e-7
Identity = 21/68 (30.88%), Postives = 35/68 (51.47%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCG 1500
            +++  C FC K F    +   H RSH G KP++C +C+++  +   L RH++T  R    S +    G
Sbjct:    5 QKKYICSFCLKPFSRSEHKIRHERSHAGVKPFQCQVCKHSFVRRDLLQRHIRTVHRTFLLSSYASMTG 72

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BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Nematostella
Match: EDO42018 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2K8])

HSP 1 Score: 73.559 bits (179), Expect = 3.738e-15
Identity = 39/88 (44.32%), Postives = 52/88 (59.09%), Query Frame = 1

Query: 1279 SEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            S+ E + ++ TCEFCG+ F + S+L  H R+HTG KP++C  C    AQS  LT H++TH   G R   C  CG  F   TTL  H+R
Sbjct:    9 SQPEDKPKEYTCEFCGRAFTHLSSLNNHTRTHTGHKPFKCDYCGKRFAQSGVLTAHLRTH--TGDRPFKCPICGREFAQTTTLSNHIR 94

HSP 2 Score: 63.1586 bits (152), Expect = 1.395e-11
Identity = 33/77 (42.86%), Postives = 47/77 (61.04%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  CG+ F   + L+ H R+HTG+KP+RC  C  A AQSS   +H  +H RE  +  +CKYC   F  ++T+ +HMR
Sbjct:   76 CPICGREFAQTTTLSNHIRTHTGQKPFRCRTCFRAFAQSSTRNKHELSHSRE--KPFNCKYCDRSFSQSSTVLRHMR 150

HSP 3 Score: 57.3806 bits (137), Expect = 1.146e-9
Identity = 28/75 (37.33%), Postives = 45/75 (60.00%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKH 1536
            C++CGK F     LT H R+HTG++P++C +C    AQ++ L+ H++TH   G +   C+ C   F  ++T  KH
Sbjct:   48 CDYCGKRFAQSGVLTAHLRTHTGDRPFKCPICGREFAQTTTLSNHIRTH--TGQKPFRCRTCFRAFAQSSTRNKH 120

HSP 4 Score: 52.373 bits (124), Expect = 6.035e-8
Identity = 28/76 (36.84%), Postives = 41/76 (53.95%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHM 1539
            C  C + F   S    H  SH+ EKP+ C  C  + +QSS + RHM+TH ++  +S  C +CG  F     L+KH+
Sbjct:  104 CRTCFRAFAQSSTRNKHELSHSREKPFNCKYCDRSFSQSSTVLRHMRTHDKD--KSYRCVHCGQVFAYLYALDKHL 177

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Nematostella
Match: EDO47692 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLH7])

HSP 1 Score: 67.0106 bits (162), Expect = 2.108e-13
Identity = 36/77 (46.75%), Postives = 46/77 (59.74%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  C K F   +NLT H R H+GEKP+RC +C    +QSS +T HM+TH  E  R   CK C   F  ++TL KH+R
Sbjct:   24 CMVCLKSFTQAANLTAHFRIHSGEKPFRCRVCGRQFSQSSSVTTHMRTHNGE--RPYKCKVCNKAFADSSTLTKHVR 98

HSP 2 Score: 59.6918 bits (143), Expect = 7.363e-11
Identity = 30/77 (38.96%), Postives = 45/77 (58.44%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  CG+ F   S++T H R+H GE+PY+C +C  A A SS LT+H++TH  E  +   C+ C   F  +  + +H R
Sbjct:   52 CRVCGRQFSQSSSVTTHMRTHNGERPYKCKVCNKAFADSSTLTKHVRTHTGE--KPYQCEICHQRFSQSGNMNRHKR 126

HSP 3 Score: 52.373 bits (124), Expect = 2.784e-8
Identity = 24/54 (44.44%), Postives = 33/54 (61.11%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +R   C+ C K F + S LT H R+HTGEKPY+C +C    +QS  + RH + H
Sbjct:   75 ERPYKCKVCNKAFADSSTLTKHVRTHTGEKPYQCEICHQRFSQSGNMNRHKRIH 128

HSP 4 Score: 49.2914 bits (116), Expect = 3.020e-7
Identity = 24/66 (36.36%), Postives = 39/66 (59.09%), Query Frame = 1

Query: 1345 SNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            S L +H R+H+G KPY+C +C  +  Q++ LT H + H  E  +   C+ CG  F  ++++  HMR
Sbjct:    7 STLRLHMRTHSGVKPYQCMVCLKSFTQAANLTAHFRIHSGE--KPFRCRVCGRQFSQSSSVTTHMR 70

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Nematostella
Match: EDO38419 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCX8])

HSP 1 Score: 71.2478 bits (173), Expect = 4.547e-13
Identity = 37/77 (48.05%), Postives = 46/77 (59.74%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  CGKVF +  NLT H R+H+GEKP++C  C    AQ+  LT HM+TH  E  +   C  CG  F  A+ L KHMR
Sbjct:  431 CTQCGKVFAHAGNLTTHMRTHSGEKPHKCTQCGKVFAQAGNLTTHMRTHSGE--KPHKCTQCGKAFAHASNLTKHMR 505

HSP 2 Score: 68.9366 bits (167), Expect = 2.308e-12
Identity = 36/77 (46.75%), Postives = 45/77 (58.44%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  CGKVF    NLT H R+H+GEKP++C  C  A A +S LT+HM+ H  E  +   C  CG  F   + L KHMR
Sbjct:  459 CTQCGKVFAQAGNLTTHMRTHSGEKPHKCTQCGKAFAHASNLTKHMRIHSGE--KPYKCTQCGKVFAHTSHLTKHMR 533

HSP 3 Score: 68.5514 bits (166), Expect = 2.846e-12
Identity = 36/77 (46.75%), Postives = 45/77 (58.44%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  CGKVF +  NLT H R+H+GEKP++C  C    AQ+  LT HM+TH  E  +   C  CG  F  A+ L  HMR
Sbjct:  347 CTQCGKVFAHAGNLTTHMRTHSGEKPHKCTQCGKVFAQAGILTTHMRTHSGE--KPHKCTQCGKAFAQASNLTTHMR 421

HSP 4 Score: 68.1662 bits (165), Expect = 4.403e-12
Identity = 37/77 (48.05%), Postives = 47/77 (61.04%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  CGK F + S+LT H R+H+GEKP++C  C  A A++S LTRHM+TH  E  +   C  CG  F  A  L  HMR
Sbjct:  291 CTQCGKAFAHASSLTEHMRTHSGEKPHKCTQCGKAFARASVLTRHMRTHSGE--KPHKCTQCGKVFAHAGNLTTHMR 365

HSP 5 Score: 67.0106 bits (162), Expect = 9.738e-12
Identity = 37/77 (48.05%), Postives = 44/77 (57.14%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  CGKVF     LT H R+H+GEKP++C  C  A AQ+S LT HM+TH  E  +   C  CG  F  A  L  HMR
Sbjct:  375 CTQCGKVFAQAGILTTHMRTHSGEKPHKCTQCGKAFAQASNLTTHMRTHSGE--KPHKCTQCGKVFAHAGNLTTHMR 449

HSP 6 Score: 65.4698 bits (158), Expect = 3.328e-11
Identity = 35/77 (45.45%), Postives = 42/77 (54.55%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  CGK F   SNLT H R+H+GEKP++C  C    A +  LT HM+TH  E  +   C  CG  F  A  L  HMR
Sbjct:  403 CTQCGKAFAQASNLTTHMRTHSGEKPHKCTQCGKVFAHAGNLTTHMRTHSGE--KPHKCTQCGKVFAQAGNLTTHMR 477

HSP 7 Score: 61.6178 bits (148), Expect = 5.628e-10
Identity = 29/52 (55.77%), Postives = 35/52 (67.31%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGRE 1467
            C  CGK F + SNLT H R H+GEKPY+C  C    A +S LT+HM+TH RE
Sbjct:  487 CTQCGKAFAHASNLTKHMRIHSGEKPYKCTQCGKVFAHTSHLTKHMRTHSRE 538

HSP 8 Score: 61.2326 bits (147), Expect = 5.930e-10
Identity = 34/77 (44.16%), Postives = 41/77 (53.25%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  CGK F   S LT H R+H+GEKP++C  C    A +  LT HM+TH  E  +   C  CG  F  A  L  HMR
Sbjct:  319 CTQCGKAFARASVLTRHMRTHSGEKPHKCTQCGKVFAHAGNLTTHMRTHSGE--KPHKCTQCGKVFAQAGILTTHMR 393

HSP 9 Score: 54.6842 bits (130), Expect = 7.455e-8
Identity = 31/77 (40.26%), Postives = 41/77 (53.25%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C  C K F +   + +H  +HT  KPY+C  C  A A +S LT HM+TH  E  +   C  CG  F  A+ L +HMR
Sbjct:  263 CPICEKDFCDYRYMIMHILTHTKYKPYKCTQCGKAFAHASSLTEHMRTHSGE--KPHKCTQCGKAFARASVLTRHMR 337

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Nematostella
Match: EDO48956 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI19])

HSP 1 Score: 67.3958 bits (163), Expect = 6.911e-13
Identity = 40/108 (37.04%), Postives = 51/108 (47.22%), Query Frame = 1

Query: 1219 KLKTEILSAYEISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            K K        I N    C   I K  ++  CE CGK F    +L  H   HTGEKPY+CHLC  A +Q   L  H +TH   G +   C+ CG  F + + L  HM+
Sbjct:    2 KFKCPTCDKAFIRNYTLQCHMLIHKNVKEHKCETCGKEFTLLKHLQRHHLVHTGEKPYKCHLCGRAFSQQGSLQAHSRTH--TGIKPYKCQICGRAFALQSPLMSHMK 107

HSP 2 Score: 59.6918 bits (143), Expect = 3.618e-10
Identity = 32/75 (42.67%), Postives = 41/75 (54.67%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKH 1536
            C  CG+ F    +L  H R+HTG KPY+C +C  A A  S L  HMKTH  E  ++  C+ CG  F    TL +H
Sbjct:   61 CHLCGRAFSQQGSLQAHSRTHTGIKPYKCQICGRAFALQSPLMSHMKTHSNE--KNFKCETCGKAFTHRNTLARH 133

HSP 3 Score: 49.2914 bits (116), Expect = 1.107e-6
Identity = 29/75 (38.67%), Postives = 38/75 (50.67%), Query Frame = 1

Query: 1285 IEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPF 1509
            I    R   CE CGK F   ++L  H R HTG +PY+CH+C  +      L  H++TH  E  R   C +CG  F
Sbjct:  136 IHSGTRPYKCEECGKTFTQTNDLKRHSRIHTGIRPYKCHVCSKSFTVEFTLVCHLRTHTGE--RPYVCDHCGKTF 208

HSP 4 Score: 48.521 bits (114), Expect = 1.777e-6
Identity = 29/77 (37.66%), Postives = 39/77 (50.65%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            CE CGK F + + L  H+  H+G +PY+C  C     Q++ L RH + H   G R   C  C   F V  TL  H+R
Sbjct:  117 CETCGKAFTHRNTLARHQLIHSGTRPYKCEECGKTFTQTNDLKRHSRIH--TGIRPYKCHVCSKSFTVEFTLVCHLR 191

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Nematostella
Match: EDO41082 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5G4])

HSP 1 Score: 66.6254 bits (161), Expect = 1.200e-11
Identity = 32/77 (41.56%), Postives = 45/77 (58.44%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C+ CG+ F + S L  H R+HTGE+P+ C  C    +    LTRHM++H   G R   C+YC   F V+ TL+ H+R
Sbjct:  142 CDICGRAFSDRSGLVKHERTHTGERPFECSFCHMMFSLKGLLTRHMRSH--TGQRPYKCEYCSAAFSVSDTLKSHLR 216

HSP 2 Score: 55.4546 bits (132), Expect = 3.177e-8
Identity = 30/77 (38.96%), Postives = 42/77 (54.55%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            C+ CGKVF    NL+ H   HTGEKPY+C +C+   A +S L  H + H  +G +   C+ C   F  +    +HMR
Sbjct:  282 CQTCGKVFVRSDNLSKHMLCHTGEKPYKCQVCERGFACTSALKSHQRRH--DGIKPYKCERCDKRFTSSNERTRHMR 356

HSP 3 Score: 54.6842 bits (130), Expect = 5.957e-8
Identity = 32/83 (38.55%), Postives = 41/83 (49.40%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R   CE+C   F     L  H R HTGE+PY+C +C     QSS L+ H+ TH   G R   C  CG  F   + L  H R+
Sbjct:  193 QRPYKCEYCSAAFSVSDTLKSHLRLHTGERPYKCEICNKGFVQSSALSSHLLTHS--GKRPYECLTCGQTFRSRSNLLYHERR 273

HSP 4 Score: 53.9138 bits (128), Expect = 1.176e-7
Identity = 35/115 (30.43%), Postives = 52/115 (45.22%), Query Frame = 1

Query: 1201 VRSDETKLKTEILSAYEISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            + + E   K EI +   + + A +        KR   C  CG+ FR+ SNL  H R H GE P+ C  C     +S  L++HM  H  E  +   C+ C   F   + L+ H R+
Sbjct:  217 LHTGERPYKCEICNKGFVQSSALSSHLLTHSGKRPYECLTCGQTFRSRSNLLYHERRHRGEAPFECQTCGKVFVRSDNLSKHMLCHTGE--KPYKCQVCERGFACTSALKSHQRR 329

HSP 5 Score: 52.7582 bits (125), Expect = 2.262e-7
Identity = 35/103 (33.98%), Postives = 51/103 (49.51%), Query Frame = 1

Query: 1249 EISNVAFNCGSEIEKEKRQDT------CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHM 1539
            +I   AF+  S + K +R  T      C FC  +F     LT H RSHTG++PY+C  C  A + S  L  H++ H  E  R   C+ C   F+ ++ L  H+
Sbjct:  143 DICGRAFSDRSGLVKHERTHTGERPFECSFCHMMFSLKGLLTRHMRSHTGQRPYKCEYCSAAFSVSDTLKSHLRLHTGE--RPYKCEICNKGFVQSSALSSHL 243

HSP 6 Score: 49.6766 bits (117), Expect = 2.216e-6
Identity = 37/98 (37.76%), Postives = 45/98 (45.92%), Query Frame = 1

Query: 1264 AFNCGSEIEKEKRQD------TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHM 1539
            AF   S++ K KR        +C  C K F     LT H R HTGE+PY C  C    +Q S   +H   H  E  RS  C  C   F  A+TL +HM
Sbjct:    7 AFKNKSDLVKHKRVHCDDKPYSCRTCDKEFTRRDALTCHIRIHTGERPYECRYCDKRFSQPSHRVQHEFKHSGE--RSHMCDICSKSFSRASTLVRHM 102

HSP 7 Score: 48.521 bits (114), Expect = 4.848e-6
Identity = 31/82 (37.80%), Postives = 40/82 (48.78%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            +R   C+ C K F   S L  H  SHT +KPY C  C  A A S+ L +H + + R G +   C  CG  F   + L KH R
Sbjct:   80 ERSHMCDICSKSFSRASTLVRHMISHTDDKPYVCTKCNKAFAYSASLVKHDRVYHR-GVKPYECDICGRAFSDRSGLVKHER 160

HSP 8 Score: 48.521 bits (114), Expect = 6.077e-6
Identity = 30/104 (28.85%), Postives = 50/104 (48.08%), Query Frame = 1

Query: 1249 EISNVAFNCGSEIEKEKRQD------TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            ++    F C S ++  +R+        CE C K F + +  T H R+HTG+KPY C +C+     ++ L RH   H   G +   C  C   F  ++ L +H++
Sbjct:  311 QVCERGFACTSALKSHQRRHDGIKPYKCERCDKRFTSSNERTRHMRTHTGDKPYTCDICKENFMYTTSLARHKLIHS--GAKPFKCDTCEKAFRSSSELTRHVK 412

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Medaka
Match: im:7142702 (B-cell lymphoma/leukemia 11B [Source:NCBI gene;Acc:101155396])

HSP 1 Score: 140.584 bits (353), Expect = 1.322e-34
Identity = 62/86 (72.09%), Postives = 70/86 (81.40%), Query Frame = 1

Query: 1291 KEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKC 1548
            KE+R DTCE+CGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K 
Sbjct:  728 KERRNDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCSYACAQSSKLTRHMKTHGQYGKEVYRCDICHMPFSVYSTLEKHMKKW 813

HSP 2 Score: 92.4337 bits (228), Expect = 3.461e-19
Identity = 37/57 (64.91%), Postives = 48/57 (84.21%), Query Frame = 1

Query: 1288 EKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            + + +  +CEFCGK+F+  SNL VHRRSHTGE+PY+CHLC +AC+Q+SKL RHMKTH
Sbjct:  371 QAQAKAKSCEFCGKIFKFQSNLIVHRRSHTGERPYKCHLCDHACSQASKLKRHMKTH 427

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Medaka
Match: bcl11ab (B-cell lymphoma/leukemia 11A [Source:NCBI gene;Acc:101156306])

HSP 1 Score: 140.198 bits (352), Expect = 1.592e-34
Identity = 65/95 (68.42%), Postives = 73/95 (76.84%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGN 1581
            +R DTCEFCGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C+ C  PF V +TLEKHM+K     S R L N
Sbjct:  706 RRSDTCEFCGKVFKNCSNLTVHRRSHTGERPYKCELCSYACAQSSKLTRHMKTHGQMGKDVYKCEICHMPFSVYSTLEKHMKKW---HSERPLAN 797

HSP 2 Score: 90.1225 bits (222), Expect = 1.866e-18
Identity = 37/50 (74.00%), Postives = 43/50 (86.00%), Query Frame = 1

Query: 1309 TCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +CEFCGK F+  SNL VHRRSHTGEKP++CHLC +AC Q+SKL RHMKTH
Sbjct:  371 SCEFCGKTFKFQSNLIVHRRSHTGEKPFKCHLCNHACTQASKLKRHMKTH 420

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Medaka
Match: bcl11aa (B-cell lymphoma/leukemia 11A [Source:NCBI gene;Acc:101158718])

HSP 1 Score: 138.658 bits (348), Expect = 7.059e-34
Identity = 61/83 (73.49%), Postives = 69/83 (83.13%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCEFCGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C+ C  PF V +TLEKHM+K
Sbjct:  821 RRSDTCEFCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKDVYKCEICQMPFSVYSTLEKHMKK 903

HSP 2 Score: 91.2781 bits (225), Expect = 1.047e-18
Identity = 38/49 (77.55%), Postives = 42/49 (85.71%), Query Frame = 1

Query: 1312 CEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            CEFCGK F+  SNL VHRRSHTGEKPY+CHLC +AC Q+SKL RHMKTH
Sbjct:  433 CEFCGKAFKFQSNLIVHRRSHTGEKPYKCHLCDHACTQASKLKRHMKTH 481

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Medaka
Match: bcl11aa (B-cell lymphoma/leukemia 11A [Source:NCBI gene;Acc:101158718])

HSP 1 Score: 136.732 bits (343), Expect = 1.644e-33
Identity = 61/83 (73.49%), Postives = 69/83 (83.13%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCEFCGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C+ C  PF V +TLEKHM+K
Sbjct:  568 RRSDTCEFCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKDVYKCEICQMPFSVYSTLEKHMKK 650

HSP 2 Score: 90.5077 bits (223), Expect = 1.419e-18
Identity = 40/75 (53.33%), Postives = 49/75 (65.33%), Query Frame = 1

Query: 1234 ILSAYEISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +L  ++         S    + +   CEFCGK F+  SNL VHRRSHTGEKPY+CHLC +AC Q+SKL RHMKTH
Sbjct:  214 LLQPFQTGGNGTGATSSSNTQMKTKCCEFCGKAFKFQSNLIVHRRSHTGEKPYKCHLCDHACTQASKLKRHMKTH 288

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Medaka
Match: BCL11B (BAF chromatin remodeling complex subunit BCL11B [Source:NCBI gene;Acc:101169989])

HSP 1 Score: 135.961 bits (341), Expect = 4.606e-33
Identity = 61/83 (73.49%), Postives = 68/83 (81.93%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRK 1545
            +R DTCEFCGKVF+NCSNLTVHRRSHTGE+PY+C LC YACAQSSKLTRHMKTHG+ G     C  C  PF V +TLEKHM+K
Sbjct:  738 RRCDTCEFCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQLGKEVYRCDICQMPFSVYSTLEKHMKK 820

HSP 2 Score: 91.2781 bits (225), Expect = 9.032e-19
Identity = 41/82 (50.00%), Postives = 56/82 (68.29%), Query Frame = 1

Query: 1213 ETKLKTEILSAYEISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +T  K+  L+   +  +  N  +  + + +  +CEFCGK F+  SNL VHRRSHTGEKPY+C LC +AC+Q+SKL RHMKTH
Sbjct:  363 QTGPKSPFLNTPPLPPMPPNSTTPPQTQNKVKSCEFCGKTFKFQSNLVVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTH 444

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Planmine SMEST
Match: SMESG000029867.1 (SMESG000029867.1)

HSP 1 Score: 888.641 bits (2295), Expect = 0.000e+0
Identity = 449/449 (100.00%), Postives = 449/449 (100.00%), Query Frame = 1

Query:  364 MSRRKQIQPQQLFIESNSVSSDIDYITCGECQKTFEFENIMVFLTHKMFHMKGSITDSPGKIGLLSSRNYLPTSILSKKESNNNYKECIQCCHCWKFFGSAWKLLQHVQRNHKISVYKIHSPRLKVLRKXXXXXXXXXXXXXXXXXXKFALSTPINGTENQDSDHQKPIMEQSKYNLSVKDDNDNICDSQSNIITCDSSIIDGNSSLKTNLSYFFEKANTGTGSVNNMMIEENNYMPANNTDAFSMSSLLSSPIVKGIKFDSTPNPNTTLSLIADQTNSVRSDETKLKTEILSAYEISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNSFGTGSSGESEISCDSRMDNSIQFGKDGSETIIPDISIPEMRN 1710
            MSRRKQIQPQQLFIESNSVSSDIDYITCGECQKTFEFENIMVFLTHKMFHMKGSITDSPGKIGLLSSRNYLPTSILSKKESNNNYKECIQCCHCWKFFGSAWKLLQHVQRNHKISVYKIHSPRLKVLRKNNNNNNINNNNNNSAINNKFALSTPINGTENQDSDHQKPIMEQSKYNLSVKDDNDNICDSQSNIITCDSSIIDGNSSLKTNLSYFFEKANTGTGSVNNMMIEENNYMPANNTDAFSMSSLLSSPIVKGIKFDSTPNPNTTLSLIADQTNSVRSDETKLKTEILSAYEISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNSFGTGSSGESEISCDSRMDNSIQFGKDGSETIIPDISIPEMRN
Sbjct:    1 MSRRKQIQPQQLFIESNSVSSDIDYITCGECQKTFEFENIMVFLTHKMFHMKGSITDSPGKIGLLSSRNYLPTSILSKKESNNNYKECIQCCHCWKFFGSAWKLLQHVQRNHKISVYKIHSPRLKVLRKNNNNNNINNNNNNSAINNKFALSTPINGTENQDSDHQKPIMEQSKYNLSVKDDNDNICDSQSNIITCDSSIIDGNSSLKTNLSYFFEKANTGTGSVNNMMIEENNYMPANNTDAFSMSSLLSSPIVKGIKFDSTPNPNTTLSLIADQTNSVRSDETKLKTEILSAYEISNVAFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRESNRFLGNSFGTGSSGESEISCDSRMDNSIQFGKDGSETIIPDISIPEMRN 449

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Planmine SMEST
Match: SMESG000011176.1 (SMESG000011176.1)

HSP 1 Score: 159.458 bits (402), Expect = 9.581e-42
Identity = 69/83 (83.13%), Postives = 74/83 (89.16%), Query Frame = 1

Query: 1300 RQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKC 1548
            R DTCE+CGK+F+NCSNLTVHRRSHTGEKPY+C LC YACAQSSKLTRHMKTHGREG  S  CKYC TPFIV +TLEKHMRKC
Sbjct:  464 RNDTCEYCGKIFKNCSNLTVHRRSHTGEKPYKCKLCNYACAQSSKLTRHMKTHGREGKSSHFCKYCNTPFIVPSTLEKHMRKC 546

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Planmine SMEST
Match: SMESG000000679.1 (SMESG000000679.1)

HSP 1 Score: 75.485 bits (184), Expect = 3.468e-14
Identity = 36/82 (43.90%), Postives = 48/82 (58.54%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
            +R   C  C K F   +NLT H+R H+GEKP+ CH+C    +QSS +T HM+TH  E  R   C +C   F  ++TL KH R
Sbjct:  342 ERPFKCNVCSKTFSQVANLTAHKRIHSGEKPFSCHICCRTFSQSSSVTTHMRTHSGE--RPYRCHHCSKAFSDSSTLTKHTR 421

HSP 2 Score: 68.1662 bits (165), Expect = 7.761e-12
Identity = 32/87 (36.78%), Postives = 48/87 (55.17%), Query Frame = 1

Query: 1282 EIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMR 1542
             I   ++  +C  C + F   S++T H R+H+GE+PYRCH C  A + SS LT+H + H  E  +   C+ C   F  +  L +HMR
Sbjct:  365 RIHSGEKPFSCHICCRTFSQSSSVTTHMRTHSGERPYRCHHCSKAFSDSSTLTKHTRVHSGE--KPYKCRICLLKFSQSGNLNRHMR 449

HSP 3 Score: 58.151 bits (139), Expect = 1.161e-8
Identity = 25/54 (46.30%), Postives = 32/54 (59.26%), Query Frame = 1

Query: 1297 KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTH 1458
            +R   C  C K F + S LT H R H+GEKPY+C +C    +QS  L RHM+ H
Sbjct:  398 ERPYRCHHCSKAFSDSSTLTKHTRVHSGEKPYKCRICLLKFSQSGNLNRHMRVH 451

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Planmine SMEST
Match: SMESG000022366.1 (SMESG000022366.1)

HSP 1 Score: 70.0922 bits (170), Expect = 2.864e-12
Identity = 45/125 (36.00%), Postives = 64/125 (51.20%), Query Frame = 1

Query: 1279 SEIEKE--KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHG-REGCRSMH-CKYCGTPFIVATTLEKHMRKCCLRESNRFLGNSFGTGSSGESEISCDSRMDN 1641
            S IE+E  K+   C++C K F   + L VH+R HTGEKPY C +C  A  QS  L RH  TH  R+   S + C++C T F   + LE H +       NR  G      ++  +  S D++ +N
Sbjct:   76 SPIEEESTKKILKCDYCDKTFTLANVLKVHQRIHTGEKPYVCEICGKAFNQSGSLNRHRNTHRYRDATDSNYICRFCNTKFPHGSLLENHEKTA---HHNRRSGRPRNLSTTDNNANSLDAKSNN 197

[Close]

BLAST of B-cell lymphoma/leukemia 11B vs. Planmine SMEST
Match: SMESG000022366.1 (SMESG000022366.1)

HSP 1 Score: 69.707 bits (169), Expect = 3.611e-12
Identity = 45/125 (36.00%), Postives = 64/125 (51.20%), Query Frame = 1

Query: 1279 SEIEKE--KRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQYACAQSSKLTRHMKTHG-REGCRSMH-CKYCGTPFIVATTLEKHMRKCCLRESNRFLGNSFGTGSSGESEISCDSRMDN 1641
            S IE+E  K+   C++C K F   + L VH+R HTGEKPY C +C  A  QS  L RH  TH  R+   S + C++C T F   + LE H +       NR  G      ++  +  S D++ +N
Sbjct:   76 SPIEEESTKKILKCDYCDKTFTLANVLKVHQRIHTGEKPYVCEICGKAFNQSGSLNRHRNTHRYRDATDSNYICRFCNTKFPHGSLLENHEKTA---HHNRRSGRPRNLSTTDNNANSLDAKSNN 197

The following BLAST results are available for this feature:

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Human
BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Celegans
BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Fly
BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Zebrafish
BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Xenopus
BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Mouse
BLAST of B-cell lymphoma/leukemia 11B vs. UniProt/SwissProt
BLAST of B-cell lymphoma/leukemia 11B vs. TrEMBL
BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Cavefish
BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Sea Lamprey
BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Yeast
BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Nematostella
BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Medaka
BLAST of B-cell lymphoma/leukemia 11B vs. Planmine SMEST

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
BCL11A	5.892e-34	65.66	BAF chromatin remodeling complex subunit BCL11A [S...	[more]
BCL11A	1.070e-33	65.66	BAF chromatin remodeling complex subunit BCL11A [S...	[more]
BCL11B	1.958e-33	71.43	BAF chromatin remodeling complex subunit BCL11B [S...	[more]
BCL11B	2.462e-33	72.29	BAF chromatin remodeling complex subunit BCL11B [S...	[more]
BCL11B	2.619e-33	72.29	BAF chromatin remodeling complex subunit BCL11B [S...	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
bcl-11	1.087e-32	57.14	Mammalian BCL (B cell lymphoma) gene homologs [So...	[more]
bcl-11	1.087e-32	57.14	Mammalian BCL (B cell lymphoma) gene homologs [So...	[more]
bcl-11	1.141e-32	57.14	Mammalian BCL (B cell lymphoma) gene homologs [So...	[more]
che-1	1.571e-13	45.45	Transcription factor che-1 [Source:UniProtKB/Swis...	[more]
che-1	2.162e-13	45.45	Transcription factor che-1 [Source:UniProtKB/Swis...	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG9650	9.395e-40	71.13	gene:FBgn0029939 transcript:FBtr0339815	[more]
CG9650	1.227e-39	71.13	gene:FBgn0029939 transcript:FBtr0309030	[more]
CG9650	1.240e-39	71.13	gene:FBgn0029939 transcript:FBtr0301240	[more]
CG9650	1.492e-39	71.13	gene:FBgn0029939 transcript:FBtr0474235	[more]
CG9650	1.509e-39	71.13	gene:FBgn0029939 transcript:FBtr0474234	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
bcl11ab	8.131e-34	73.49	BAF chromatin remodeling complex subunit BCL11A b ...	[more]
bcl11aa	1.446e-33	73.49	BAF chromatin remodeling complex subunit BCL11A a ...	[more]
bcl11ba	1.781e-33	69.77	BAF chromatin remodeling complex subunit BCL11B a ...	[more]
znf296	2.263e-33	59.43	zinc finger protein 296 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
im:7142702	2.525e-32	68.60	im:7142702 [Source:ZFIN;Acc:ZDB-GENE-050411-48]	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
aqp7	1.016e-33	73.49	aquaporin 7 [Source:Xenbase;Acc:XB-GENE-484060]	[more]
aqp7	1.261e-26	73.24	aquaporin 7 [Source:Xenbase;Acc:XB-GENE-484060]	[more]
aqp7	1.906e-26	84.48	aquaporin 7 [Source:Xenbase;Acc:XB-GENE-484060]	[more]
bcl11a	9.036e-26	83.93	BCL11A, BAF complex component [Source:NCBI gene;Ac...	[more]
bcl11a	1.142e-25	83.93	BCL11A, BAF complex component [Source:NCBI gene;Ac...	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Bcl11a	4.194e-34	65.66	B cell CLL/lymphoma 11A (zinc finger protein) [Sou...	[more]
Bcl11b	1.288e-33	71.43	B cell leukemia/lymphoma 11B [Source:MGI Symbol;Ac...	[more]
Bcl11b	1.641e-33	72.29	B cell leukemia/lymphoma 11B [Source:MGI Symbol;Ac...	[more]
Bcl11b	2.166e-33	72.29	B cell leukemia/lymphoma 11B [Source:MGI Symbol;Ac...	[more]
Zfp296	7.591e-25	61.54	zinc finger protein 296 [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9H165\|BC11A_HUMAN	2.829e-33	65.66	B-cell lymphoma/leukemia 11A OS=Homo sapiens OX=96...	[more]
sp\|Q9C0K0\|BC11B_HUMAN	1.258e-32	72.29	B-cell lymphoma/leukemia 11B OS=Homo sapiens OX=96...	[more]
sp\|Q99PV8\|BC11B_MOUSE	1.515e-32	72.29	B-cell lymphoma/leukemia 11B OS=Mus musculus OX=10...	[more]
sp\|E9Q6W4\|ZN296_MOUSE	5.310e-24	61.54	Zinc finger protein 296 OS=Mus musculus OX=10090 G...	[more]
sp\|Q8WUU4\|ZN296_HUMAN	9.012e-23	60.00	Zinc finger protein 296 OS=Homo sapiens OX=9606 GN...	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
V4B224	1.555e-41	37.20	Uncharacterized protein (Fragment) OS=Lottia gigan...	[more]
A0A0R3U2B3	4.540e-40	70.41	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A5K3EUQ7	7.663e-40	74.44	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
K1PWX7	1.018e-39	64.66	B-cell lymphoma/leukemia 11B OS=Crassostrea gigas ...	[more]
A0A3S1A0R7	7.641e-39	67.62	Uncharacterized protein (Fragment) OS=Elysia chlor...	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
znf296	2.625e-34	70.93	zinc finger protein 296 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
BCL11B	1.057e-33	71.43	BAF chromatin remodeling complex subunit BCL11B [S...	[more]
bcl11aa	1.620e-33	72.29	BAF chromatin remodeling complex subunit BCL11A [S...	[more]
im:7142702	6.371e-33	72.29	B-cell lymphoma/leukemia 11A-like [Source:NCBI gen...	[more]
ENSAMXT00000055377.1	6.773e-15	43.42	zinc finger protein 692 [Source:NCBI gene;Acc:1030...	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000007831.1	2.098e-13	42.11	pep scaffold:Pmarinus_7.0:GL477655:47469:47963:1 g...	[more]
ENSPMAT00000006856.1	3.449e-13	43.75	pep scaffold:Pmarinus_7.0:GL476534:515915:516469:1...	[more]
ENSPMAT00000008278.1	7.301e-13	40.23	pep scaffold:Pmarinus_7.0:GL477891:43090:46668:-1 ...	[more]
ENSPMAT00000004838.1	7.789e-13	41.56	pep scaffold:Pmarinus_7.0:GL495265:3215:3667:-1 ge...	[more]
ENSPMAT00000004611.1	1.112e-12	29.80	pep scaffold:Pmarinus_7.0:GL476524:167506:168579:-...	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
ZAP1	2.437e-11	40.26	Zinc-regulated transcription factor; binds to zinc...	[more]
AZF1	7.708e-9	33.75	Zinc-finger transcription factor; involved in diau...	[more]
MSN2	5.974e-8	37.10	Stress-responsive transcriptional activator; activ...	[more]
COM2	3.122e-7	40.32	Transcription factor that binds IME1 Upstream Acti...	[more]
YGR067C_mRNA	4.641e-7	30.88	Putative protein of unknown function; contains a z...	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO42018	3.738e-15	44.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47692	2.108e-13	46.75	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38419	4.547e-13	48.05	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48956	6.911e-13	37.04	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41082	1.200e-11	41.56	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
im:7142702	1.322e-34	72.09	B-cell lymphoma/leukemia 11B [Source:NCBI gene;Acc...	[more]
bcl11ab	1.592e-34	68.42	B-cell lymphoma/leukemia 11A [Source:NCBI gene;Acc...	[more]
bcl11aa	7.059e-34	73.49	B-cell lymphoma/leukemia 11A [Source:NCBI gene;Acc...	[more]
bcl11aa	1.644e-33	73.49	B-cell lymphoma/leukemia 11A [Source:NCBI gene;Acc...	[more]
BCL11B	4.606e-33	73.49	BAF chromatin remodeling complex subunit BCL11B [S...	[more]

BLAST of B-cell lymphoma/leukemia 11B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000029867.1	0.000e+0	100.00	SMESG000029867.1	[more]
SMESG000011176.1	9.581e-42	83.13	SMESG000011176.1	[more]
SMESG000000679.1	3.468e-14	43.90	SMESG000000679.1	[more]
SMESG000022366.1	2.864e-12	36.00	SMESG000022366.1	[more]
SMESG000022366.1	3.611e-12	36.00	SMESG000022366.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30004449 ID=SMED30004449|Name=B-cell lymphoma/leukemia 11B|organism=Schmidtea mediterranea sexual|type=transcript|length=1774bp
CACTAACCAGGAATTAATAGGTGGATTTTCACTGGTCGGCTATTCGAATT
CTGATTGGATACATGCAGCCGGTTGTTGCAGTTCATGTAACAAGCAAACT
TCAGCGATAATTTCTCTCAACTGACCAACACAGCAATGCAATTGGACAGC
GTAGTTCACATGACGTCAATATCTTTCTCCTATATTCAAACGGCAATGGT
CAACTGAGCGTTGAGTGAAGCAGTGTTGAGAGTCTAAAATAGATTGTCGA
AACTGTACCAATTCATTTTGACAAGACTTTGAATCAAGTTCAAATAAAAA
ACCAACAAGAAAGAATTTTTTTCAGAAAAAAAAATTAAAAGAAAAAAATC
TGTCAATTCGAAAATGTCGCGCCGGAAACAAATACAACCTCAACAACTAT
TTATAGAATCGAATTCAGTGAGTTCCGATATCGACTATATAACTTGCGGA
GAATGCCAGAAAACGTTTGAATTTGAAAATATTATGGTATTTCTCACTCA
CAAAATGTTCCACATGAAAGGCTCAATAACGGATTCTCCTGGAAAAATCG
GATTATTATCCTCAAGAAATTATTTACCAACCTCGATTTTATCCAAAAAA
GAATCAAACAATAATTACAAGGAATGTATTCAATGTTGTCATTGTTGGAA
GTTTTTCGGTTCCGCTTGGAAGCTTTTGCAGCACGTTCAAAGAAACCACA
AAATATCAGTTTATAAAATTCATTCTCCTAGGCTGAAGGTGTTGAGAAAA
AATAATAATAATAACAATATTAATAATAATAATAATAATTCCGCTATTAA
CAACAAATTTGCTCTATCTACACCAATTAATGGGACAGAAAATCAAGATT
CAGATCATCAAAAGCCGATTATGGAGCAAAGCAAATATAACTTATCAGTC
AAAGACGACAATGACAATATTTGCGACTCTCAAAGCAACATAATTACTTG
TGATAGTTCTATAATTGATGGAAACAGTTCTCTGAAAACTAATCTGTCGT
ATTTCTTTGAAAAGGCCAACACAGGAACTGGTTCGGTCAACAATATGATG
ATTGAGGAGAACAATTATATGCCAGCCAACAACACGGACGCTTTTTCCAT
GTCGTCTTTGCTGTCGTCTCCGATTGTTAAGGGAATCAAATTCGATTCGA
CTCCAAATCCAAACACGACTCTCAGCTTGATTGCCGACCAAACGAATTCC
GTTAGAAGCGACGAAACGAAACTGAAAACCGAAATCCTTTCCGCCTATGA
AATTTCCAATGTCGCTTTCAATTGCGGCTCGGAAATCGAAAAAGAAAAGC
GACAGGACACCTGTGAATTCTGTGGGAAAGTTTTTCGGAATTGCAGCAAT
CTCACGGTTCATCGGAGAAGCCACACGGGCGAGAAACCGTATCGGTGTCA
TTTGTGTCAATATGCCTGTGCACAGTCGTCGAAATTGACCCGGCACATGA
AAACTCACGGAAGGGAAGGCTGTCGAAGCATGCATTGTAAATATTGTGGC
ACTCCTTTTATCGTTGCTACGACTTTAGAGAAACATATGAGAAAGTGTTG
CTTGAGAGAGTCAAATCGGTTTTTGGGAAATTCATTTGGAACCGGCTCGA
GTGGAGAGAGTGAAATTTCGTGTGATTCAAGAATGGACAACTCGATTCAG
TTCGGTAAAGATGGCTCAGAAACGATTATTCCAGATATCAGCATTCCAGA
AATGCGAAATTAAATCTATCGGTCCCACAAAGGGATTTTGTACAGCATTT
TGCAATAAAATCATGAGAAGCCTT

protein sequence of SMED30004449-orf-1

>SMED30004449-orf-1 ID=SMED30004449-orf-1|Name=SMED30004449-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=450bp
MSRRKQIQPQQLFIESNSVSSDIDYITCGECQKTFEFENIMVFLTHKMFH
MKGSITDSPGKIGLLSSRNYLPTSILSKKESNNNYKECIQCCHCWKFFGS
AWKLLQHVQRNHKISVYKIHSPRLKVLRKNNNNNNINNNNNNSAINNKFA
LSTPINGTENQDSDHQKPIMEQSKYNLSVKDDNDNICDSQSNIITCDSSI
IDGNSSLKTNLSYFFEKANTGTGSVNNMMIEENNYMPANNTDAFSMSSLL
SSPIVKGIKFDSTPNPNTTLSLIADQTNSVRSDETKLKTEILSAYEISNV
AFNCGSEIEKEKRQDTCEFCGKVFRNCSNLTVHRRSHTGEKPYRCHLCQY
ACAQSSKLTRHMKTHGREGCRSMHCKYCGTPFIVATTLEKHMRKCCLRES
NRFLGNSFGTGSSGESEISCDSRMDNSIQFGKDGSETIIPDISIPEMRN*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000418	head
PLANA:0000478	pharynx musculature
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036236	Znf_C2H2_sf
IPR015880	Znf_C2H2-like
IPR013087	Znf_C2H2_type
IPR007087	Znf_C2H2

Vocabulary: **molecular function**
Term	Definition
GO:0003676	nucleic acid binding
GO:0046872	metal ion binding
GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
GO:0003674	molecular_function
GO:0005515	protein binding

Vocabulary: **biological process**
Term	Definition
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007283	spermatogenesis

Vocabulary: **cellular component**
Term	Definition
GO:0005575	cellular_component
GO:0005634	nucleus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR013087	Zinc finger C2H2-type	SMART	SM00355	c2h2final6	coord: 89..112 e-value: 1.4 score: 18.0 coord: 315..337 e-value: 2.2 score: 17.3 coord: 373..393 e-value: 82.0 score: 5.2 coord: 343..365 e-value: 0.0066 score: 25.7 coord: 26..50 e-value: 34.0 score: 8.6
IPR013087	Zinc finger C2H2-type	PFAM	PF00096	zf-C2H2	coord: 316..337 e-value: 3.7E-5 score: 23.9 coord: 343..365 e-value: 0.0022 score: 18.4 coord: 375..394 e-value: 0.0032 score: 17.9
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 345..365
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 317..337
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 91..112
IPR013087	Zinc finger C2H2-type	PROSITE	PS50157	ZINC_FINGER_C2H2_2	coord: 315..342 score: 15.48
IPR013087	Zinc finger C2H2-type	PROSITE	PS50157	ZINC_FINGER_C2H2_2	coord: 343..370 score: 9.889
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 316..342 e-value: 2.2E-12 score: 48.6
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 343..403 e-value: 1.2E-11 score: 46.5
None	No IPR available	PANTHER	PTHR45993	FAMILY NOT NAMED	coord: 210..401 coord: 19..148
None	No IPR available	CDD	cd18804	SF2_C_priA	coord: 317..380 e-value: 0.00184911 score: 37.6095
IPR036236	Zinc finger C2H2 superfamily	SUPERFAMILY	SSF57667	beta-beta-alpha zinc fingers	coord: 316..365