Family with sequence similarity 184 member A

Overview
NameFamily with sequence similarity 184 member A
Smed IDSMED30004447
Length (bp)3498
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Family with sequence similarity 184 member A (SMED30004447) t-SNE clustered cells

Violin plots show distribution of expression levels for Family with sequence similarity 184 member A (SMED30004447) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Family with sequence similarity 184 member A (SMED30004447) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Family with sequence similarity 184 member A (SMED30004447) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30004447

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30004447h1SMcG0013764 SmedASXL_009434SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30004447h1SMcG0013764 SmedASXL_005152SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30004447h1SMcG0013764 SmedASXL_001028SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30004447h1SMcG0013764 SmedASXL_000397SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pharynxSMED30004447h1SMcG0013764 dd_Smed_v4_16975_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30004447h1SMcG0013764 dd_Smed_v4_16975_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30004447h1SMcG0013764 dd_Smed_v4_16975_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30004447h1SMcG0013764 dd_Smed_v4_16975_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30004447h1SMcG0013764 dd_Smed_v4_16975_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30004447h1SMcG0013764 dd_Smed_v6_16975_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Match: FAM184A (family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991])

HSP 1 Score: 108.612 bits (270), Expect = 3.103e-23
Identity = 74/231 (32.03%), Postives = 125/231 (54.11%), Query Frame = 3
Query: 2859 LEKQLQNAINEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
            L+K++Q+ ++EN + L K+++  G +  R + + ++++R  E ++    ++ +  +   H  E      DFNK   L KE    L   L E++E+++ R ++ EDI++I  L A     ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP                    N+ A+++  + N       +L P+P SP HD   N +KPL    PP   K+F
Sbjct:  766 LDKEVQH-LHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPN---RLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 992          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Match: FAM184A (family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991])

HSP 1 Score: 108.227 bits (269), Expect = 5.104e-23
Identity = 74/231 (32.03%), Postives = 125/231 (54.11%), Query Frame = 3
Query: 2859 LEKQLQNAINEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
            L+K++Q+ ++EN + L K+++  G +  R + + ++++R  E ++    ++ +  +   H  E      DFNK   L KE    L   L E++E+++ R ++ EDI++I  L A     ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP                    N+ A+++  + N       +L P+P SP HD   N +KPL    PP   K+F
Sbjct:  844 LDKEVQH-LHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPN---RLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 1070          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Match: FAM184A (family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991])

HSP 1 Score: 101.679 bits (252), Expect = 5.741e-23
Identity = 72/230 (31.30%), Postives = 121/230 (52.61%), Query Frame = 3
Query: 2859 LEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
            L+K++Q+     + L K+++  G +  R + + ++++R  E ++    ++ +  +   H  E      DFNK   L KE    L   L E++E+++ R ++ EDI++I  L A     ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP                    N+ A+++  + N       +L P+P SP HD   N +KPL    PP   K+F
Sbjct:   38 LDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHP---NRLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 264          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Match: FAM184A (family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991])

HSP 1 Score: 107.457 bits (267), Expect = 7.562e-23
Identity = 74/231 (32.03%), Postives = 125/231 (54.11%), Query Frame = 3
Query: 2859 LEKQLQNAINEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
            L+K++Q+ ++EN + L K+++  G +  R + + ++++R  E ++    ++ +  +   H  E      DFNK   L KE    L   L E++E+++ R ++ EDI++I  L A     ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP                    N+ A+++  + N       +L P+P SP HD   N +KPL    PP   K+F
Sbjct:  886 LDKEVQH-LHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPN---RLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 1112          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Match: FAM184A (family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991])

HSP 1 Score: 97.4413 bits (241), Expect = 9.404e-20
Identity = 54/144 (37.50%), Postives = 82/144 (56.94%), Query Frame = 3
Query: 3117 RLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
            RL E++E+++ R ++ EDI++I  L A     ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP                    N+ A+++  + N       +L P+P SP HD   N +KPL    PP   K+F
Sbjct:  803 RLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPN---RLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 943          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Match: fam184a (family with sequence similarity 184 member A [Source:ZFIN;Acc:ZDB-GENE-041014-214])

HSP 1 Score: 111.309 bits (277), Expect = 1.351e-26
Identity = 70/210 (33.33%), Postives = 112/210 (53.33%), Query Frame = 3
Query: 2883 INEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP-------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL 3452
            +NEN + L K+++  G +  + + + ++++R+ E ++    ++ +  L   H  ET+  ++DFNKAQ L K+KI  L   L   +++F  R +R ED++ I  L       E  +++L ++K+F QLELVNRET+FNKIFNA+PNVG++NP                   N+ A               +L PLP SP H    N +KPL
Sbjct:   40 LNENISTLTKELELKGKEVLKIRSEANQQIRAHEQDLCKKHEREMAELNALHHRETQNMLSDFNKAQELLKDKISALQILLEGTEDKFRNRESRPEDLQTIAELKDMVAEREALVKKLVDDKKFYQLELVNRETSFNKIFNANPNVGVINPLVKQKRKNDKSATRFSSSANLRANVEASGTGSGQPQPNRLEPLPNSPIHQLEPNASKPL 249          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Match: fam184a (family with sequence similarity 184 member A [Source:ZFIN;Acc:ZDB-GENE-041014-214])

HSP 1 Score: 116.701 bits (291), Expect = 7.014e-26
Identity = 164/675 (24.30%), Postives = 346/675 (51.26%), Query Frame = 3
Query:  276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAE-----IQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFE-VEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNN--ELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTD--YVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKE--------EFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLM-KLSSDKDSDIET-NLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEI 2240
            +QDLH KMSKKIAQLTKVIYALNTKND++E  + TLK+ H +E+QQIL ET  ++   + K+   ++  ++IQ L++++  +E +  +   +FE +++   +     + ++ ++   +++ +++++ S+E+ L  +  L +  E EKR  +E L+  + +E+Q +      +  QS+       +E   QL  A+ +     ++     K +L++++E ++ +    ++    E+ ++T+    E +  +K    E  K    +E+ L+    ++R EL       ++   K   L+   +  E+NI +L+ ++ +     E    EI+ R    EL+  +DR ++++ E+  K  QI  L+  A  +  +   ++ E +K+  + K++  E +  A  +K +T D     QI TL++              S+ + K+ +E EL+    + + +  +  ++S+ +  +E   K ++  + IQ L E        + + + ++ER+   +    L+ +LD L+ +L  K+   + ++  L+E+       +K   Q L  ++ ++  +K    +L+ +L + +    ET NL  +  L+  +E QK  ++   K + I+E+   K +K++ EL++KW +TLR+E  +LR ++ E   ++K+ A+  + + K+ E+
Sbjct:   44 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALDEFETYRQRVEDMQLCTEAQHTQRVVSMSREVEEMRRSFEEKLRSFAQLQSQFEQEKRQALEELRSGHRQEVQELL-----RSHQSQNANYSKDQEKLGQLHKAEVDSLNERVEELKQDKKRLVEEYEAKLNKAQAFYER-ELEAMKRTQQMTAENLLAWKKTEAELRKEFQAQEAALQKTLGKLRSELQRVQDEARESREKSHKLQASLMTAENNIKELHKQLEEVTKDAE--IVEIRQREGECELEASRDRVQQQATEILLKASQIGSLQ--ATQMTHEAVIRDLESEKSRLKDKVLRLEEERGALQNKCQTLDDRQRQQIVTLEK--------------SLREEKQIYEKELMNLRAKYEDDT-AHFKESHSRALEELSRKHRASLENIQSLSEKEKNRLLSDMEDQFNKERTSLEEQKRILREELDSLREELTAKLNMANNEVSRLQEL-------VKQGEQTLGSSEGHISNLKDAQKKLLEELDATRARLRETSNL--LTALQGEMETQKQQHDA--KLISIKEEEKLKMDKMALELELKWTETLRQECKKLREELREDHEEDKRSALTQLAQNKDQEL 682          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Match: fam184a (family with sequence similarity 184 member A [Source:ZFIN;Acc:ZDB-GENE-041014-214])

HSP 1 Score: 105.145 bits (261), Expect = 1.135e-23
Identity = 60/180 (33.33%), Postives = 112/180 (62.22%), Query Frame = 3
Query:  234 TLNGFK-YTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRI 770
            T  G++ Y     S +QDLH KMSKKIAQLTKVIYALNTKND++E  + TLK+ H +E+QQIL ET  ++   + K+   ++  ++IQ L++++  +E +  +   +FE +++   +     + ++ ++   +++ +++++ S+E+ L  +  L +  E EKR  +E L+  + +E+Q +
Sbjct:    3 TGAGWQHYYNPAGSYTQDLHLKMSKKIAQLTKVIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALDEFETYRQRVEDMQLCTEAQHTQRVVSMSREVEEMRRSFEEKLRSFAQLQSQFEQEKRQALEELRSGHRQEVQEL 182          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Match: zgc:85722 (zgc:85722 [Source:ZFIN;Acc:ZDB-GENE-040516-7])

HSP 1 Score: 92.8189 bits (229), Expect = 1.434e-18
Identity = 51/167 (30.54%), Postives = 105/167 (62.87%), Query Frame = 3
Query:  276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITE 776
            +QDLH KMSKKIAQLTKVIYALNTKND++E  + +LK+ H +E+Q IL ET  ++   + K+    +  +++Q L++++  +E +  +   +FE++++   +     + ++ ++   +++ +++++  +E+ L  +  +    E EKR  +++LK  + +E++ + E
Sbjct:   54 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEDAIQSLKEAHDEEVQHILTETREKILHYKSKIGDEADLKRRLQSLEESVELHEHMKRQALAEFEMYRQRMEDTQLCTEAQHTQRVVSMSREVEEMRHEFEEKLRTFSQVQAQFEQEKRHALDDLKSAHRQEVEDLLE 220          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Match: fam184a (family with sequence similarity 184 member A [Source:ZFIN;Acc:ZDB-GENE-041014-214])

HSP 1 Score: 73.9442 bits (180), Expect = 1.103e-12
Identity = 41/148 (27.70%), Postives = 90/148 (60.81%), Query Frame = 3
Query:  327 VIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRI 770
            VIYALNTKND++E  + TLK+ H +E+QQIL ET  ++   + K+   ++  ++IQ L++++  +E +  +   +FE +++   +     + ++ ++   +++ +++++ S+E+ L  +  L +  E EKR  +E L+  + +E+Q +
Sbjct:    1 VIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALDEFETYRQRVEDMQLCTEAQHTQRVVSMSREVEEMRRSFEEKLRSFAQLQSQFEQEKRQALEELRSGHRQEVQEL 148          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Match: ip6k2 (inositol hexaphosphate kinase 2 [Source:Xenbase;Acc:XB-GENE-971466])

HSP 1 Score: 110.538 bits (275), Expect = 9.133e-24
Identity = 75/219 (34.25%), Postives = 119/219 (54.34%), Query Frame = 3
Query: 2859 LEKQLQNAINENA-YLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILN-------------------PNMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLP 3455
            L KQL  A+ EN   L K++D  G +    + + ++++R QE ++     + + +L   H  E +  I +  K Q L+ EK   L   L E++E++  R +R ED++II  L       ++ I++L ++K+F QLELVNRETNFNK+FNASPNVG++N                   PN+ A+++  + N       +L P+P SP HD   + +KPLP
Sbjct:  891 LNKQLM-ALKENINSLTKELDFKGKEILCIRSEANQQIRVQEQDLNKKHKEDLNDLTSAHIREKQILIAEMAKTQALFMEKNSALQKSLTEMEEKYQNRESRPEDLQIISELKEMVTERDQLIKKLIDDKKFYQLELVNRETNFNKVFNASPNVGVINPLVKQKKKNDKSTNRFVSVPNLSALESGGMGNGHPP---RLDPIPNSPIHDIEFSSSKPLP 1105          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Match: ip6k2 (inositol hexaphosphate kinase 2 [Source:Xenbase;Acc:XB-GENE-971466])

HSP 1 Score: 105.531 bits (262), Expect = 3.418e-22
Identity = 61/165 (36.97%), Postives = 91/165 (55.15%), Query Frame = 3
Query: 3018 NLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILN-------------------PNMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLP 3455
            +L   H  E +  I +  K Q L+ EK   L   L E++E++  R +R ED++II  L       ++ I++L ++K+F QLELVNRETNFNK+FNASPNVG++N                   PN+ A+++  + N       +L P+P SP HD   + +KPLP
Sbjct:  922 DLTSAHIREKQILIAEMAKTQALFMEKNSALQKSLTEMEEKYQNRESRPEDLQIISELKEMVTERDQLIKKLIDDKKFYQLELVNRETNFNKVFNASPNVGVINPLVKQKKKNDKSTNRFVSVPNLSALESGGMGNGHPP---RLDPIPNSPIHDIEFSSSKPLP 1083          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Match: ip6k2 (inositol hexaphosphate kinase 2 [Source:Xenbase;Acc:XB-GENE-971466])

HSP 1 Score: 97.0561 bits (240), Expect = 1.278e-19
Identity = 164/683 (24.01%), Postives = 352/683 (51.54%), Query Frame = 3
Query:  276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQ---IQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYK-SRIF--EYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKI-----QSLEKDC--LEKESNISKLNIEVSQHK-STIERLTSEIKSRNN----ELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECES-DLEKSNKKREKEFVLKEKSFQDEIQ-------KLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMK-LSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEID 2243
            + +LH KMSKKIAQLTKVIYALNTKND++E  +  +K+ H +EIQ+IL ET  ++   + K+    +   +I+ L++++  ++ +      +FE+++    +     + ++V++   +++ +++++  +++ + ++  +    E +KR  +++L+     EIQ +    K +  Q+  L  G +  ++   +Q+ D   +I+     + +L++D+E ++ +                  +E E+E  K S++F  E      QKE+E+K ++ Q ++ L++K+  I   E ++      +L + C  L+   N ++ NI+V Q +   +++    + S+ N    EL   ++R ++++ E+  K   I  L+  A ++ Q+ T ++ E +KA  + KI   E +     SK++  D        +R  +++     +   + +  +  +E EL+    R+K E E+  L++ + K  +E  LK ++  +  Q       KL+ E Q + ++E S+  +    L+  L+ LK DL  K+   +++ + L+++       +K   Q L   + ++ ++K   NRL K L   ++   ETN   +  ++  LE+++  +E I   ++ +E +  K +K++ +L++KW +TLR+E  ++R ++    A++K+ AI  + + K  EI+
Sbjct:   44 TAELHLKMSKKIAQLTKVIYALNTKNDEHESGIQAIKEAHEEEIQKILAETHEKILLYKNKVSEETDLKHKIKALEESLEEHKKMKHHALTEFEVYKHRVEDMQLCAEAQHVQRIVTMSREVEEMRKKFDERIHNFMQIQVQFEKDKRSALDDLRTS-RLEIQEL---LKAQHNQNATLNKGQETLLEMHRLQVEDLNKKIEDMRLERKRLVEDYEAKLTKAQAF--------------YEHEMEALKRSQMFTAESLHACKQKEAEIK-KDFQSQEALLQKNLGILKTEFQVVQEEAVNLREKCQKLQISLNTAETNIQVLQKQLENVKQGEMSLLSKQNDMESELAAARERIQQQATELVLKASHIGMLQ--ATHMTQEATIQDLESEKARIKEKIARLEEERTLLQSKNQNLD--------ERQRQQMVALERKINEAKQTQRECYEKELINL--RIKFEEETMQLKEFHTKTVEEMSLKHQAALEAAQSTANKEKKLQMELQQQFEKEISELEESKNHLRQQLENLKEDLTEKLTSANQENVQLQDL-------VKKSEQGLGSAECHITSLKDAQNRLQKELDLTRERLRETN-DSLFAVQEELEKERQQHEVILNAIREEERL--KMDKVARDLELKWTETLRQECSKVREELKLQHAEDKKSAIAQLLQLKEREIN 685          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Match: ENSXETT00000035830.1 (protein FAM184B [Source:NCBI gene;Acc:100488800])

HSP 1 Score: 59.6918 bits (143), Expect = 2.425e-8
Identity = 57/195 (29.23%), Postives = 100/195 (51.28%), Query Frame = 3
Query:  210 NNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYE----QLLDDYYTLNTNMESEKRLK-IENLKVDYEKEIQRITEE 779
            N+Q    N   G +    Q +   +LH KM KKIAQLTKVIYALN K D+ E  + +LK+ H  EI  I  ET  +    + K+    +  Q+IQ L++++     +  +T   F  ++++  E       ++ E+  +L++ +  +K+ +E    QL D+  +L    ++ +R K +E L      E+Q +++E
Sbjct:    6 NHQHSQYNGTKGQQMLFSQ-AYPHELHGKMCKKIAQLTKVIYALNLKVDEYEYNILSLKEAHQDEIDLISSETKEKFLQYESKIGEEQHLRQRIQSLEESLEKNNMIKEQTLADFAKYKRQMEEWESRTKAEHNERISVLSKEMLSMKTDFETKVKQLTDEADSLRKECKASERDKAMETLNEKLNAEVQTLSQE 199          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Match: wdcp (WD repeat and coiled coil containing [Source:Xenbase;Acc:XB-GENE-5729803])

HSP 1 Score: 56.6102 bits (135), Expect = 3.304e-7
Identity = 122/558 (21.86%), Postives = 236/558 (42.29%), Query Frame = 3
Query:  486 QIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKE-KQSKALIVGSQ------KEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKE-MNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQ---KESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNI---SKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLES-VGRMKKECESDLEKS-----NKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKD---NNRLMKLS----SDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNV-QIQE 2075
            Q QELK        LL+  +    L Q   N     +D   +E  ++LN+  K + +  EQ   D    N   E  K+L+      D+ KE  R +++  +K  K ++ L + ++      +E+Q  +    AE++       +   D E +  E + +    L  E+ +K ++   EV+E K  +FE   + +    +E+  KI+       + +K+  + +LE K Q +EK   E ES +     +  EV+     I    +++   N EL  L ++  EK N +  +I +         +L ++  + E +  + +    +++    E  N S + T  +         +  +   +  E+ +   K K +  I+L+    G +K E ++ ++KS     + KR    V   K  ++++  +K   ++  DE+     + +      L  + ND  +K++    +     +      + +K L+  L   K+N   +K+D    N  +K      +D D  ++   KE DRL   L+  K L EN+ KN+ QI+E
Sbjct: 1417 QTQELKH-------LLSPQRAPERLLQLAQNN----QDTLVIEMDELLNRAAK-VTADGEQTGKDAERTN---ERAKQLE------DFVKETLRASKDIYDKAVKLNETLGIPNKTLDKSFQELQKDIDSMMAELRRKSLRNQKNTADDELKAAEALLNRVKKLFLEAHKKNEDLNNEVKE-KLGLFEEKLDDVWDLLREARGKIKAADDLSTVNQKN--MTELERKKQGVEKGKKETESVLGDGDSIMTEVNNLAQIINEAENDLSDMNKELPPLTEQLNEKINNLTQEIAR--------RDLPEQILQAENQAAQLIDSSAVLDGILAEAKNLSFNATVAFN------AYSNIKDLIDDAEDTAKEAKAKANEAIDLVTGPQGSLKDEAKNAIQKSFRVLSDAKRHSGDV---KDNENDLAGIKNRLENA-DEKNQNMLQALNDTFGKLALIPNDTLVKIQTAKDKAKQANDTASDVLERLKDLNLNLLGLKQNYTALKEDVAKTNAAVKDPVENITDADGRVKQLEKEADRLLDKLKPIKELQENLGKNISQIKE 1932          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Match: Fam184a (family with sequence similarity 184, member A [Source:MGI Symbol;Acc:MGI:1923156])

HSP 1 Score: 92.8189 bits (229), Expect = 6.497e-19
Identity = 67/215 (31.16%), Postives = 115/215 (53.49%), Query Frame = 3
Query: 2856 NLEKQLQNAINENA-YLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPIN 3437
            +L+K++Q+ ++EN   L K+++  G +  R + + ++++R  E ++    ++ +  +   H  E      DFNK   L KE    L   L +++E+++ R +R EDI++I  L +     ++ I++L E+ +F QLELVNRETNFNKIFN SP VG++NP                    N+ A+++  + N       +L P+P SP HD   N
Sbjct:  285 DLDKEVQH-LHENINTLTKELELKGKEILRVRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDIQMIAELKSLITERDQVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINPLAKQKKKNDKSAANRFVSVPNLSALESSGMGNGHPT---RLEPIPNSPAHDVEFN 495          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Match: Fam184a (family with sequence similarity 184, member A [Source:MGI Symbol;Acc:MGI:1923156])

HSP 1 Score: 91.2781 bits (225), Expect = 6.532e-19
Identity = 67/215 (31.16%), Postives = 115/215 (53.49%), Query Frame = 3
Query: 2856 NLEKQLQNAINENA-YLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPIN 3437
            +L+K++Q+ ++EN   L K+++  G +  R + + ++++R  E ++    ++ +  +   H  E      DFNK   L KE    L   L +++E+++ R +R EDI++I  L +     ++ I++L E+ +F QLELVNRETNFNKIFN SP VG++NP                    N+ A+++  + N       +L P+P SP HD   N
Sbjct:  141 DLDKEVQH-LHENINTLTKELELKGKEILRVRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDIQMIAELKSLITERDQVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINPLAKQKKKNDKSAANRFVSVPNLSALESSGMGNGHPT---RLEPIPNSPAHDVEFN 351          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Match: Fam184a (family with sequence similarity 184, member A [Source:MGI Symbol;Acc:MGI:1923156])

HSP 1 Score: 88.5817 bits (218), Expect = 1.107e-18
Identity = 56/160 (35.00%), Postives = 97/160 (60.62%), Query Frame = 3
Query: 2856 NLEKQLQNAINENA-YLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP 3332
            +L+K++Q+ ++EN   L K+++  G +  R + + ++++R  E ++    ++ +  +   H  E      DFNK   L KE    L   L +++E+++ R +R EDI++I  L +     ++ I++L E+ +F QLELVNRETNFNKIFN SP VG++NP
Sbjct:  111 DLDKEVQH-LHENINTLTKELELKGKEILRVRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDIQMIAELKSLITERDQVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINP 269          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Match: Fam184a (family with sequence similarity 184, member A [Source:MGI Symbol;Acc:MGI:1923156])

HSP 1 Score: 93.5893 bits (231), Expect = 1.199e-18
Identity = 67/215 (31.16%), Postives = 115/215 (53.49%), Query Frame = 3
Query: 2856 NLEKQLQNAINENA-YLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPIN 3437
            +L+K++Q+ ++EN   L K+++  G +  R + + ++++R  E ++    ++ +  +   H  E      DFNK   L KE    L   L +++E+++ R +R EDI++I  L +     ++ I++L E+ +F QLELVNRETNFNKIFN SP VG++NP                    N+ A+++  + N       +L P+P SP HD   N
Sbjct:  888 DLDKEVQH-LHENINTLTKELELKGKEILRVRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDIQMIAELKSLITERDQVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINPLAKQKKKNDKSAANRFVSVPNLSALESSGMGNGHPT---RLEPIPNSPAHDVEFN 1098          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Match: Fam184a (family with sequence similarity 184, member A [Source:MGI Symbol;Acc:MGI:1923156])

HSP 1 Score: 83.5741 bits (205), Expect = 5.219e-18
Identity = 43/91 (47.25%), Postives = 61/91 (67.03%), Query Frame = 3
Query: 3060 TDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP 3332
             DFNK   L KE    L   L +++E+++ R +R EDI++I  L +     ++ I++L E+ +F QLELVNRETNFNKIFN SP VG++NP
Sbjct:   14 ADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDIQMIAELKSLITERDQVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINP 104          
BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Match: sp|Q8NB25|F184A_HUMAN (Protein FAM184A OS=Homo sapiens OX=9606 GN=FAM184A PE=1 SV=3)

HSP 1 Score: 107.457 bits (267), Expect = 3.631e-22
Identity = 74/231 (32.03%), Postives = 125/231 (54.11%), Query Frame = 3
Query: 2859 LEKQLQNAINEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
            L+K++Q+ ++EN + L K+++  G +  R + + ++++R  E ++    ++ +  +   H  E      DFNK   L KE    L   L E++E+++ R ++ EDI++I  L A     ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP                    N+ A+++  + N       +L P+P SP HD   N +KPL    PP   K+F
Sbjct:  886 LDKEVQH-LHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPN---RLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 1112          
BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Match: sp|Q9ULE4|F184B_HUMAN (Protein FAM184B OS=Homo sapiens OX=9606 GN=FAM184B PE=2 SV=3)

HSP 1 Score: 70.8626 bits (172), Expect = 6.447e-11
Identity = 49/148 (33.11%), Postives = 81/148 (54.73%), Query Frame = 3
Query:  240 NGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRV---EGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLL 674
             G  + MD D     +H KM KKIAQLTKVIYALNT+ D+ E ++  L++ H +E+Q  + ET  R+   +G  ++  L     Q+IQ L+  +   + L  E   +    + E+ ER    + ++ E+   L++ + +LK+ YE+ L
Sbjct:   22 GGAGWRMDCDP---QMHVKMCKKIAQLTKVIYALNTRQDEAEASMEALREAHQEELQNAVAETKARLLQEQGCAEEEAL----LQRIQALESALELQKRLTEEALAESASCRLETKERELRVEAEHAERVLTLSREMLELKADYERRL 162          

HSP 2 Score: 58.5362 bits (140), Expect = 3.816e-7
Identity = 44/156 (28.21%), Postives = 83/156 (53.21%), Query Frame = 3
Query: 2889 ENAYLKKQIDDFGNDYSRSQQDFSEKLRSQ----ESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKE--IERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNM 3338
            ENA L+  +     +  + QQ+ ++KLR Q    E   +    + +  L+ +H +E +  + DF+ AQ   + ++  L + L +  E+     +R ED+++I  L  QT+L E+E  I++L EE+RF      +  ++ N+ F+ +P+ G L P+M
Sbjct:  810 ENAQLQDAVRRLRAEVEQHQQE-AQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQAQLQARLAALEAELKDSGEKPGKGASRPEDLQLIGRL--QTRLKEREDIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSM 962          
BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Match: sp|Q60675|LAMA2_MOUSE (Laminin subunit alpha-2 OS=Mus musculus OX=10090 GN=Lama2 PE=1 SV=2)

HSP 1 Score: 69.3218 bits (168), Expect = 2.541e-10
Identity = 118/567 (20.81%), Postives = 250/567 (44.09%), Query Frame = 3
Query:  474 NNTQQIQELKQTIASYEDLLTETKQKFELFQKESNE----RTK-----EKDLKNVEQT----QMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSK-----SETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECESDLEKSNK--KREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLK---NDLNIK---VKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMK------LSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNV-QIQE 2075
            N TQ+++ L     + E L+   +        E+NE     TK     E+  ++ E+T    + L + IK L    E + +    LN  + ++ +    NL+ + +KEI R+ +E ++K+ Q+       QKE+                A+D+L+   E  +K +N LF    A++++  K+ + ++ EYK+++ +     + +E+  K ++        +K+  I  LE K +++E    + E+ + + N  + +    +  + S I   ++   +L   +EE S+++    ++IKD + +AE + Q  +   +    +     I++E      N +      S   DY+ + + + R  +EL +   +  +S +              G +K++ +  L+KS +     K+     K   +++  LK    ++L+    + S ++  L   +D+L    ND   K   VK K ++  +  +  + + K++      LK+N   L       N ++K      + +D  + +    +E DRL   L+  K L +N++KN+ +I+E
Sbjct: 1610 NTTQELKHLLSPQRAPERLIQLAEGNVNTLVMETNELLTRATKVTADGEQTGQDAERTNSRAESLEEFIKGLVQDAEAINEKAVQLNETLGNQDKTAERNLE-ELQKEIDRMLKELRSKDLQT-------QKEV----------------AEDELVA-AEGLLKRVNKLFGEPRAQNEDMEKDLQQKLAEYKNKLDDAW--DLLREATDKTRDANRLSAANQKNMTI--LETKKEAIEGSKRQIENTLKEGNDILDEANRLLGEINSVIDYVDDIKTKLPPMSEELSDKIDDLAQEIKD-RRLAEKVFQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFRAYSNIKDYIDEAEKVAREAKELAQGATKLATSPQ--------------GLLKEDAKGSLQKSFRILNEAKKLANDVKGNHNDLNDLK----TRLETADLRNSGLLGALNDTMDKLSAITNDTAAKLQAVKEKAREANDTAKAVLAQVKDLHQNLDGLKQNYNKLADSVAKTNAVVKDPSKNKIIADAGTSVRNLEQEADRLIDKLKPIKELEDNLKKNISEIKE 2128          
BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Match: sp|Q0KK56|F184B_MOUSE (Protein FAM184B OS=Mus musculus OX=10090 GN=Fam184b PE=2 SV=1)

HSP 1 Score: 65.0846 bits (157), Expect = 3.949e-9
Identity = 45/146 (30.82%), Postives = 81/146 (55.48%), Query Frame = 3
Query:  240 NGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINN-TQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLL 674
             G  + MD D    ++H KM KKIAQLTKVIYALNT+ D+ E+++ ++++ H +++Q    ET  R+   Q +         ++IQ L+  +   + L  E   +    + E+ ER    + ++ E+  +L++ + +LK+ YE+ L
Sbjct:   24 GGSGWRMDCDP---EMHVKMCKKIAQLTKVIYALNTRQDEVEVSVESIREAHQEDLQDTGAETRTRLPQEQSRTSEDAETLLKRIQTLENALELQKRLTQEALAESASCKLETKERELRVEAEHAERVLILSKEMLELKADYEKRL 166          

HSP 2 Score: 58.9214 bits (141), Expect = 2.976e-7
Identity = 34/108 (31.48%), Postives = 61/108 (56.48%), Query Frame = 3
Query: 3021 LKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKE--IERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNM 3338
            L+ +H +E +  + DF+ AQ   + ++  L + L E  E+     +R ED+++I  L  QT+L E+E  I +L EE+RF      +  ++ N+ F+ +P+ G L P+M
Sbjct:  739 LRQEHRKEMQAMVADFSGAQARLQARLAALETELKESGEKAGKGTSRPEDLQLIGRL--QTRLKEREDIIRQLTEERRFHYAAFPSAVSHRNRSFSFNPHPGYLTPSM 844          
BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Match: sp|P24043|LAMA2_HUMAN (Laminin subunit alpha-2 OS=Homo sapiens OX=9606 GN=LAMA2 PE=1 SV=4)

HSP 1 Score: 62.7734 bits (151), Expect = 2.370e-8
Identity = 127/580 (21.90%), Postives = 242/580 (41.72%), Query Frame = 3
Query:  474 NNTQQIQELKQTIASYEDLLTETKQKFELFQKESNE----RTK-----EKDLKNVEQT----QMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKI----KQIKDLK-----SIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLES--VGRMKKECESDLEKSNK--KREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIK---VKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLM----------------KLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNV-QIQE 2075
            N TQ+++ L     + E L+   +        E NE     TK     E+  ++ E+T    + L + IK+L    E + +    LN  + +       NL+   +KEI ++ +E + K  ++       QKEI                A+D+L+   E  +K++  LF     E++E  K+   ++ +YK+++ +     + +E+  KI+E      + +K+  +  LE K +++E    + E+ + + N  + +      RL  EI S  + ++ +Q +    S E+  KI    ++IKD K     S AE+   +  +    L   L E K ++  +   A  + S   DY+ + + + +                E    +HE   L +   G +K++ +  L+KS +     K+     K  +D +  LK   ++  D       + +      L  + ND   K   VK K +Q           +   K +  Q+ E  +NL  +KK+ N+L                 K+ +D D+ ++   +E DRL   L+  K L +N++KN+ +I+E
Sbjct: 1614 NMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLE-GLQKEIDQMIKELRRKNLET-------QKEI----------------AEDELVA-AEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAW--DLLREATDKIREANRLFAVNQKN--MTALEKKKEAVESGKRQIENTLKEGNDILDE----ANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATA-AFKAYSNIKDYIDEAEKVAK----------------EAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENA-DARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQ----------ANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKE 2132          
BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Match: A0A1S3IWQ8 (protein FAM184A-like OS=Lingula unguis OX=7574 GN=LOC106168200 PE=4 SV=1)

HSP 1 Score: 247.284 bits (630), Expect = 1.264e-63
Identity = 312/1159 (26.92%), Postives = 586/1159 (50.56%), Query Frame = 3
Query:  240 NGFKYTMDQDS-----LSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQK-------FELFQKESNERTKEKDLKNVEQTQM--LNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQI----QLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEY--GKNSIQKESELKIQENQMRK---ELIEKSTFIKDLELK----IQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEM-----------ASKIKQ---IKDLKSIAENLQQK--FTEKERELKKALTEIKIMNEESK--EMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEK-LKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRL-MKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFNDQIRD--LQTQ----LSEKANITIDEHKEEVRSLQRKISLLEEQSK---TVTNTHRLELER-------------VASAKLKLDCNYQ-----NLE---KQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNM---GAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSF 3476
            NG   T+ Q +     ++QD+H KMSKKIAQLTKVIYALNTKND++E  + ++K  H +E+QQ++ ET  ++E  + +M   +       ELK+ I + E L  E +Q+       F+ F++ + ER  E  LK  E  ++  L+Q +  +K  +E+ L  +  +  + ES +R  +ENLK  + KE+    E+ +N +   ++ +   ++ ++     Q+   + +I+     K ++  D+E ++ +    +D    +     +N + E     SRI +    +N I+K+     QE Q +K   +LIE+ +  +D   K    +Q+ EK   ++ S+   L+ ++S  K    +  + +K    EL   ++R  E++ +M           A++++    IKDL+S    L+ +  + EKERE    L    +  EE K  ++ +  +S   D  ++ Q L+   E       E  +  EK L+ +HE E++E + +M KE              E   + K+  + I +LK+E Q K++  + + ++ I  +K + ++++ DL+ K+K  ++++  LE++       +K   Q L     ++ ++K+ +++L  +L S K +++     +   L+  LE+ +++++   +  Q+  ++  K ++LS +LD KW DTLR+E  +LR+++ E   ++K+ A++ + K K+ EI      +E   ++  +++S  +  +     E   L      +   + + ++  ++E    +AK++E L+  +   I+NL+        Q + E    +E  ER    KH+ E++           +K  +   + VK   D+ RD  L+TQ    LSEK  +     K E+    R    LE+ +K   T  N  R+ELER             + S +L+ +  ++     NLE   +Q+Q  +++   ++++++  G +  + + + +++LR +E ++    ++ + +L   H  ET+  + +FN+AQ+L K+KI  L   L E ++ +  R +R ED+E+I+ L    +  E+ ++RL +EK++ QLELVNRETNFNK+FN  PNVG+LNP M                 S  +L PLPGSP H++ +NP KPLPP++ K F
Sbjct:   14 NGKYGTLPQTNPKDAEITQDMHLKMSKKIAQLTKVIYALNTKNDEHEAVIQSIKDHHEEEMQQLITETRVKLENYRTRMGGDV-------ELKKKITALEALNAEHQQQKQQALEDFQNFKRRAEER--EMQLKTEESQKVIQLSQEVLTIKKHFEEQLSKFDQVKADFESNQRTALENLKKVHAKEL----EDLRNAQSSQQSDLSKERERLEQLYSQQIDQLKGQIEELNGDKKKIADDYEDKLSKAKAFYDK-ELDVLRNAQNSDME-----SRISDLLAQQNKIKKD--FAYQEGQFKKRIDDLIEQLSRSEDEIAKQKEQLQNYEKMIQDRSSDSDTLSRQLSDAKHETAQAITRLKEVEGELAASKERCSEQAADMLKKSTLLGQLEATRLQNEATIKDLESQLSKLKDRSAWLEKERE---GLQNKTLSQEEEKNHQLKSLERS-LEDLSLEKQALKERYERDLNSLEESHAKREKELQNNHEAEMME-LKKMHKE--------------ELENQRKASTEMITQLKKENQDKIEALQKQHNEEITSMKAEYERVQGDLSHKLKTAEEEVRRLEKL-------VKESEQGLGSASSHIDSLKEASDKLKAELDSTK-AELRAVSNQKSNLQAELEKLRAMHDTKMREAQL--ELKTKLDQLSKDLDAKWTDTLRKECLKLRSELTEQKEEDKRAALQQLAKMKDEEIAAAREGWERKVTQLLDEISMLKRNIDAKSSESSELLADLKQKAAAEEKRLRDQMNEAADEYAKKVEALERIHAEKIKNLE-------AQRIKE----VEEMERTLTSKHMEEMS---------NTIKAQKALIESVKDQADKQRDQDLETQHKIHLSEKETL-----KSEL--AHRHAMELEQMNKAHNTQMNAARMELERAIELSKQKERDFEIRSTELQEEVRHREKHISNLEAEIRQVQEGLDQ---MRREVEFKGKEILKIRSEANQQLRKREEQLAQQHEEQVNSLSADHLRETQDMLGEFNRAQDLLKDKISALQIMLEEAEDNYRNRESRPEDLEMIKQLQKALEDREEYMKRLEDEKKYYQLELVNRETNFNKVFNTQPNVGVLNPFMKPKKKGDKGPTKYTSSPSLNRLQPLPGSPVHEEKLNPIKPLPPTAVKKF 1092          
BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Match: A0A2T7Q188 (FAM184 domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_02058 PE=4 SV=1)

HSP 1 Score: 228.409 bits (581), Expect = 1.924e-57
Identity = 287/1141 (25.15%), Postives = 550/1141 (48.20%), Query Frame = 3
Query:  273 LSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITE-------EWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDA-LSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKE---SELKIQENQMRKE---LIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEV----SQHKSTIERLTSEIKSRNNELQRLQD--RNEEKSNEMASKIKQIKDL---KSIAENLQQKFTEKERELKKALTEIKIMNEE-------SKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSH----EIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKK--DNNRL-MKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSK--YETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFND-------QIRDLQTQLSEKANITIDEHKEEVRSLQRKISLLEEQSKTVTNTHRLELERVASAKLKLDCNYQNLEKQLQNAINEN----AYLKKQIDDF--------------GNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP------NMGAXXXXXX--XXXXXXSFQKLTPLPGSPFHDDPINPAKPLP-PSSRKSF 3476
            ++QD+H KMSKKIAQLTKVIYALNTKND+NE+ L   K QH +E + +L +   +++  + K++   ++ +Q+  L+  I+ +E   +  +++    ++E+  R +  +     Q Q L Q +   K  +E+ ++ +       E +   +++ +++ + +E++++         EW N+       ++  +   +I+    + E  SH+  + ++ +D+  ++ +    ++  L A  + +T +FE E+   +          +Q+E   ++   QE ++RK+   L+ +    +DL         D L++E+   KL  E+    S  +ST+++L   ++++   L +LQD  RN   S E    + Q  DL    ++   L+    ++  ++++ + +I+ + +E        K +  C KS+TT+ V Q++ L++  E   +    E  S++K    H    +  L E +  ++K+    LE+  K R        K+  D++Q+ K++ ++K  EE++K +     ++ + +Q+K +L  K K  ++++  L  +    +  +   S  +   K+   T+K   D  R  +K +    + ++    E+D+L+L             K+ + Q ++      L+AELD KWA+T+R E  +LR ++      E++ A+E + + K+ E+         H +  +  +S+  ++ ++A    E       N+ Q   +++  +L           E+ K +  + V +Q L++K + + LQ++ +  +  E  E+A    HL ++    + H+  +    +E E     +  D       +   LQT+L E+       H+E +R +QR  +       +V    RLEL+R      +   ++Q   ++LQ  I+++      LK ++                  +D  ++Q D  E LR  E ++K    + + N    H+ E +  I  FNKAQ + K+KI EL   L+E +E++  R +R ED+E+I  L  + +  E  + +L EEKRF QLELVNRETNFNK+F++SPNVG+LNP        GA        +   + +  +L PLPGSP HD  +NP KPLP P+  K F
Sbjct:   29 VTQDMHLKMSKKIAQLTKVIYALNTKNDENEVVLQIFKDQHEEEKKSLLADMETKIKHYRSKLEEESDHRRQMNILQTRISDFEQQQSSVEEQIAQLKEEAKAREQLLEGSYSRQMQQLTQDVLRAKREFEEHMEGFEAWKMQAEKKHMTELQEVEIKHAQELEQLRSFQRNQDTEWLNQ-----CAVIEEKYSDEIRQLKEKLEA-SHV-ERLKMEEDYVEKLAKAQAFYEQELKALQQSETSSFEGELNALR----------VQQEKLRNDFSAQERELRKQIDSLVRQLADAEDL--------ADALKQENE--KLTQEMKSKDSSAESTVQQLQQALQNKEAALVQLQDVERNLAASKERC--LDQAADLLKKSALIGELEAHRVQRAAQVEEMMKQIEHLKQELSRAEAEQKTLQLCQKSQTTEQVSQLEFLKQ-REVTKQRHEREIHSLKKASEEHLHQVQTSLQEKLAAIEKQ---HLEEKEKDR--------KAALDDLQQSKQDLEAKFWEEKTKLNDEKNSIQAEFEQVKAELLAKCKQAEEEVARLSSLVQESENGLGAASSHISSLKDAAATLKAELDKTRTELKNTKLHSASLQV---ELDKLQLLYN---------TKSAEWQLELKSLLESLAAELDAKWAETMRTECSKLRQEVTAQKDDERRAALEHLARLKDEEMVTDRAGLASHITYLKGQVSELNHKLDLAHSSREDDK----NNMQAALEVERARL---------EAELHKAQQDHKVAVQELEEKHQNSLLQTIQQKDAEREEGEKALKAIHLEDMQAQLSAHKLALVAAKEEAEQLLKARLKDVQEAHCLKQGQLQTELEER-------HEEILRKVQRDHA-------SVIQAARLELDRAVEISKQKTRDHQLQVQELQENISQHETHIVKLKDEVRKLQAGISSLNVIIVQKDHDAQQAQVDAKEHLRQVEEQLKKEQIRALDNQAADHKHEHEMMIVQFNKAQEILKDKISELQILLLEAEERYRQRDSRPEDLELIHQLRLEVQERELRVAQLIEEKRFYQLELVNRETNFNKVFSSSPNVGLLNPLQLKNKKKGAEGVPAKYLSAPSLGAPTRLDPLPGSPMHDSILNPTKPLPQPAFTKKF 1089          
BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Match: V3ZZK5 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_231741 PE=4 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 2.136e-35
Identity = 146/520 (28.08%), Postives = 261/520 (50.19%), Query Frame = 3
Query: 1989 LKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFED--HKSKTQ-NDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSL-IESHERAWADKHLIEINLLTNEHXXXXXXXXXXX-------XXXYVKQFNDQIRDLQTQLSEKANITIDE----HKEEVRS----LQRKISLLEEQSKTVTNTHRLE-LERVASAKLKLDCNYQNLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLPPSSRK 3470
            L EID+LKL    Q +  +   K          K + L  ELD KWA+TL+ ET +LR  + E    EK  A+  +  +   ++  LT  +E   H    Q  DL +   + +              S+ +E+++ ++L +SE +    KE+ + +  Y   I ++ +  +EN+L+S+ E + L +   E+   +KH+ ++ +    H   ++   ++        E   +KQ   ++  L+ +LSEK     ++    H+ E+R+    L+R I +   + K   N  R+E L+   + + +   N +   + L+ AI E   LK+ I +      + Q +  ++++  E E +  +++ + NL+  H ++  + + DFN AQ L K+KI  +  +L E ++++  R +R ED+E+I  L    +  E  ++ L +EKRF QLELVNRETNFNKIFN +PN+G++NP           +    ++      Q+L P+P SP HD  +NP++PLPP ++K
Sbjct:    9 LAEIDKLKLQHASQLTEADVTSKG---------KLDALKTELDAKWAETLKNETNKLRKQIAEQLESEKHSAVLQLTLQHEKQVAELTSEWEGKVHALTIQITDLQRSANKNS--------------SKSSEELERLRLQMSELEKKLQKEMSEAEEDYARKI-SVMEAAQENQLKSLIERKDLELSEVEKKIKNKHVEDLQIQLTAHRAAVQNIQEQADKLRHDRETTLIKQHQQELDKLRLELSEKLEKDFEDVKRKHEAEIRAARIELERAIEI--SKQKDRDNHSRIEELQMEITKRERTIMNLEEETRNLKRAIEE---LKRDIKERDKQMKQVQNEAKKQIKQLEDEFRVEYERNVDNLQADHLQQINEMVGDFNTAQELLKDKISSIQIQLEEAEDRYRNRESRPEDLELIMQLRDAIQERELRVKELIDEKRFFQLELVNRETNFNKIFNTTPNIGVMNPLNPVKPKNKKNEKPLKHSSAPALSQRLDPIPNSPLHDGNLNPSRPLPPFNKK 499          
BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Match: R7V5R4 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_107275 PE=4 SV=1)

HSP 1 Score: 144.436 bits (363), Expect = 8.731e-35
Identity = 81/215 (37.67%), Postives = 126/215 (58.60%), Query Frame = 3
Query: 2841 DCNYQNLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP-----NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLPPSSRK 3470
            D    +LE +LQN       + ++++  G D  R + + +   RS E +++  F   + +L  +H+ E +Q +T+F +AQ + K+KI EL   L E +++++ R +R ED+E+IQ L    +  +++I++L +EKR  Q+ELVNRETNFNK+FN  P VG++NP     +  A   K           +L PLPGSPFHD   N AKPLPP S+K
Sbjct:   32 DQTISHLETELQNLQKGIDEMSRELEAKGKDVLRIRSEANAAARSLEDQVQKQFKSELNDLMDQHQNEAQQMLTEFTEAQEILKDKISELRILLEEAEDRYMNRESRAEDLEMIQNLQMAIREAQQQIQKLMDEKRHYQMELVNRETNFNKMFNGDPKVGVMNPLSYPTHKKAKGDKNGVRGSPSIHNRLDPLPGSPFHDGQFNTAKPLPPPSKK 246          
BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Match: A0A2G8L3Z4 (FAM184 domain-containing protein (Fragment) OS=Stichopus japonicus OX=307972 GN=BSL78_08123 PE=4 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 7.814e-34
Identity = 165/639 (25.82%), Postives = 294/639 (46.01%), Query Frame = 3
Query: 1764 LKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFNDQIRDLQTQLSEKANITID----EHKEEVRSLQRKISL--------LEEQSKTVTNTHRLELERVASAKLKLDCNYQNLEKQLQNAINEN-AYLKKQIDDFGN---DYSRSQQDFSEKLRSQE-SEIKHNFDQVILNLK---------------MKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAXXXXXXXXXXXXSFQ----------------------KLTPLPGSPFHDDPINPAKPL-------PPSSRKSFDNS*IFV 3497
            +K +L++L+ DL  K+K  ++    L +I   +D       Q L     ++  +KK+N++L         ++   + E+  LK +LE  KS + +  +   + ED  +K + LS +LD KW++TLR+E  +LR ++ E   ++K  A+E +   KN EI+     +E   ++ + ++S     ++   ++          Q  +++ +++  L+     H +E+  L+ S +   + LK++ +E  ++  ++  SL   H +  ADK                           +++  + ++ LQ +  E     +D    EHK  +  L+ +++         L    KT     R+ELER    + + D   Q+    LQ  + +   ++ K  DD      D SRS+++   + ++QE  +++   ++ I ++K                +H  ET+  + +FN+AQ+L K+KI  L   L E ++++  R +RDED+E+I +L       ++ + +LN+EKRF QLEL+NRETNFNK+FN  PNVGILNP     K       +  S                        +L PLP SP HD  +NP KPL        P+  K F N  I V
Sbjct:  429 IKRELEELQRDLTAKLKRAEEDAQKLSKILQERD-------QGLGSANSHIDGLKKNNSQLKTEIDLMQKELRERISEVHTLKTSLE--KSKHSHATEIAGLHEDGKKKIDHLSRDLDEKWSETLRKECDKLRQELTEQHREDKNAALEQINLLKNQEIEETRGGWEQRVTELRREISDLRGSLSSKSDKAKAELAQLQRQSEQELNKLKFDLATATENHQRELADLQKSLEREKEKLKEQQQEEMMKLESKLTSL---HNKTLADK---------------------------MEEHKEAVKSLQIESEESRRAELDIRLMEHKRSLDKLRLELTQRHSAEMDQLARAHKTQMAAARMELERAIELRQQQDRANQSRVDDLQGHVTQRETHISKLEDDIQKLKMDISRSKEEI--EFKAQEIMKVQGEAERRIRDVKEVLARSQKDELDSQSAEHLRETQGMLGEFNRAQDLLKDKISALQIMLEEAEDKYRNRESRDEDLEMIGSLKEMVAEKDQVLFKLNDEKRFFQLELINRETNFNKVFNTQPNVGILNPLAKPRKRGSSEAPRYVSAPNLNSSGMMVSASSSSAGSPSNPRLEPLPDSPIHDIQLNPKKPLREKNGAGKPTKGKRFINXMIDV 1026          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Cavefish
Match: fam184a (family with sequence similarity 184 member A [Source:NCBI gene;Acc:103041903])

HSP 1 Score: 122.094 bits (305), Expect = 1.466e-27
Identity = 184/800 (23.00%), Postives = 379/800 (47.38%), Query Frame = 3
Query:  276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQ--LIKDHERQMKEMNDLFDALSAESKEKTKNFEFEV---EEYKSRIFEYGKNSIQKESE----LKIQENQMRKELIEKSTFIKDLELKIQS------------------LEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELL-------ESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLM-KLSSDKDSDIE-TNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLK-------KKFEEN-KLQSVTETQSLIESH 2543
            +QDLH KMSKKIAQLTKVIYALNTKND++E  + TLK+ H +E+QQIL ET  ++   + K+   ++  ++IQ L++++  +E +  +   +FE +++   +     + ++ ++   +++ +++++ S+E+ L  +  +    E EKR  +E L+  + +E+Q +      +  QS                      Q+  Y+KDQ  L + H+++++ +++  + L  + K   + +E ++   + +  R  E  K + Q  +E     K  E ++RKE   +   ++    K++S                  L+      E+NI  L+ ++ +     E +    K    EL+  +DR ++++ E+  K  QI  L++     +    + E E  +   ++  + EE   + N S++       QI +L++              ++ + K+++E ELL       E     K      LE+ +KK        + S + E  +L  E + + ++ERS   +   +L+  LD L+ +L+ K+   + ++  L+EI       +K   Q L   K ++ ++K+   +L+ +L + +    E TNL  +  L+  +E QK  +E   K +  +E+   K +K++ EL++KW +TLR+E  +LR ++ E   + K+ A+  + + K  E+     +++         +S  +  +     +     +   +Q +++ + +   L E ++ H +  E+L+ ++   IQ+++       K+ EE  + Q   E QS+ E+H
Sbjct:   42 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALAEFESYRQRVEDMQLCTEAQHTQRVVTMSREVEEMRRSFEEKLRSFGQVQAQFEQEKRQALEELRTSHRQEVQEML-----RSHQS----------------------QNANYSKDQEKLGQLHKQEVEALSERVEELKQDKKRLVEEYEAKLNKAQAFYERELEAMKRTQQMTAENLLAWKKTEAELRKEFQAQEAALQKTLGKLRSELQRVQDESRESREKSHKLQASLTASENNIKDLHKQLDEVTQDAEIIAIRQKEAEVELEATRDRVQQQATEILLKASQIGSLQATQMTHEAAIRDLESEKSRLKDKVVRLEEERGALQNKSQALDERQRQQILSLEK--------------TLREEKQAYEKELLNLRSKYEEDTAHFKDAQSRALEELSKKHRAALENTQSSSEKEKNRLLAEMEQQFEKERSALEEQKRRLREQLDSLREELSAKLSMANSEVSRLQEI-------VKEGEQGLGSAKGHISSLKEAQEKLLEELDATRARLRETTNL--LTALQGEMETQKQQHEA--KLITTKEEEKLKMDKMALELELKWTETLRQECKKLREELREDHEEGKRMALTQLAQSKEQELGTARESWQRKVEDLLEQISLLKQSLEMQLSQSQRSLQQLQAQFSQEREHLGQQLQELEMEHQRREERLREAHCCAIQDMQEARQHDLKELEERLRQQHHMELQSMREAH 789          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Cavefish
Match: fam184a (family with sequence similarity 184 member A [Source:NCBI gene;Acc:103041903])

HSP 1 Score: 121.709 bits (304), Expect = 1.961e-27
Identity = 166/692 (23.99%), Postives = 333/692 (48.12%), Query Frame = 3
Query:  276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQ--LIKDHERQMKEMNDLFDALSAESKEKTKNFEFEV---EEYKSRIFEYGKNSIQKESE----LKIQENQMRKELIEKSTFIKDLELKIQS------------------LEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELL-------ESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLM-KLSSDKDSDIE-TNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEID 2243
            +QDLH KMSKKIAQLTKVIYALNTKND++E  + TLK+ H +E+QQIL ET  ++   + K+   ++  ++IQ L++++  +E +  +   +FE +++   +     + ++ ++   +++ +++++ S+E+ L  +  +    E EKR  +E L+  + +E+Q +      +  QS                      Q+  Y+KDQ  L + H+++++ +++  + L  + K   + +E ++   + +  R  E  K + Q  +E     K  E ++RKE   +   ++    K++S                  L+      E+NI  L+ ++ +     E +    K    EL+  +DR ++++ E+  K  QI  L++     +    + E E  +   ++  + EE   + N S++       QI +L++              ++ + K+++E ELL       E     K      LE+ +KK        + S + E  +L  E + + ++ERS   +   +L+  LD L+ +L+ K+   + ++  L+EI       +K   Q L   K ++ ++K+   +L+ +L + +    E TNL  +  L+  +E QK  +E   K +  +E+   K +K++ EL++KW +TLR+E  +LR ++ E   + K+ A+  + + K  E+ 
Sbjct:   42 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALAEFESYRQRVEDMQLCTEAQHTQRVVTMSREVEEMRRSFEEKLRSFGQVQAQFEQEKRQALEELRTSHRQEVQEML-----RSHQS----------------------QNANYSKDQEKLGQLHKQEVEALSERVEELKQDKKRLVEEYEAKLNKAQAFYERELEAMKRTQQMTAENLLAWKKTEAELRKEFQAQEAALQKTLGKLRSELQRVQDESRESREKSHKLQASLTASENNIKDLHKQLDEVTQDAEIIAIRQKEAEVELEATRDRVQQQATEILLKASQIGSLQATQMTHEAAIRDLESEKSRLKDKVVRLEEERGALQNKSQALDERQRQQILSLEK--------------TLREEKQAYEKELLNLRSKYEEDTAHFKDAQSRALEELSKKHRAALENTQSSSEKEKNRLLAEMEQQFEKERSALEEQKRRLREQLDSLREELSAKLSMANSEVSRLQEI-------VKEGEQGLGSAKGHISSLKEAQEKLLEELDATRARLRETTNL--LTALQGEMETQKQQHEA--KLITTKEEEKLKMDKMALELELKWTETLRQECKKLREELREDHEEGKRMALTQLAQSKEQELG 681          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Cavefish
Match: fam184a (family with sequence similarity 184 member A [Source:NCBI gene;Acc:103041903])

HSP 1 Score: 102.449 bits (254), Expect = 1.630e-21
Identity = 55/165 (33.33%), Postives = 105/165 (63.64%), Query Frame = 3
Query:  276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRI 770
            +QDLH KMSKKIAQLTKVIYALNTKND++E  + TLK+ H +E+QQIL ET  ++   + K+   ++  ++IQ L++++  +E +  +   +FE +++   +     + ++ ++   +++ +++++ S+E+ L  +  +    E EKR  +E L+  + +E+Q +
Sbjct:   42 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALAEFESYRQRVEDMQLCTEAQHTQRVVTMSREVEEMRRSFEEKLRSFGQVQAQFEQEKRQALEELRTSHRQEVQEM 206          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Cavefish
Match: zgc:85722 (zgc:85722 [Source:ZFIN;Acc:ZDB-GENE-040516-7])

HSP 1 Score: 94.7449 bits (234), Expect = 3.440e-19
Identity = 57/196 (29.08%), Postives = 118/196 (60.20%), Query Frame = 3
Query:  276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQA 863
            +QDLH KMSKKIAQLTKVIYALNTKND++E  + +LK+ H  E+Q IL ET +++   + KM       +++Q L++++  +E +  +   +F+++++   +     + ++ ++   +++ +++++  +E+ L  +  +    E EK   +E+LK+ + +E+Q + E    ++ QS +  +  +K  ++  A+ +A
Sbjct:    4 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEEAIQSLKEAHEDEVQHILSETRDKILQYKSKMGDEAELKRRLQSLEESVELHEHMKRQALAEFQMYRQRMEDSQLCAEAQHTQRVVSMSREVEEMRHDFEEKLRSFSQVQAQFEQEKLRNMEDLKLAHRQELQELLE---TQQSQSASSCLDQEKLAELHRAELEA 196          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Sea Lamprey
Match: fam184a (family with sequence similarity 184 member A [Source:ZFIN;Acc:ZDB-GENE-041014-214])

HSP 1 Score: 64.3142 bits (155), Expect = 1.403e-10
Identity = 33/127 (25.98%), Postives = 74/127 (58.27%), Query Frame = 3
Query:  324 KVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNM 704
            +VIYALNTKND++E  ++ L++ H++E+QQ   ET +R+   Q ++ +     ++ + L++ +AS   L  + +++ E +++   ER   +D ++ ++   L+  + D+K  +E  +  + +L   +
Sbjct:    1 QVIYALNTKNDEHEAAVSVLREAHAEEMQQFAAETRHRLLRYQSRLGVESELREKARSLEEALASEGSLRRQAQEQLEAYRRHVEERDAGRDAEHADRILALSTQMLDMKRDFEAKILGFTSLQKRL 127          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Medaka
Match: fam184a (family with sequence similarity 184 member A [Source:NCBI gene;Acc:101175129])

HSP 1 Score: 112.079 bits (279), Expect = 1.575e-24
Identity = 60/159 (37.74%), Postives = 103/159 (64.78%), Query Frame = 3
Query: 2859 LEKQLQNAINEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP 3332
            L++Q+ + +NEN + L K+++  G +  + + + ++++R+ E E+    ++ +  +   H  ET+  ++DFNKAQ + K+KI  L   L   +E+F  R +R ED+++I  L       E  +++L ++K+F QLELVNRETNFNK+FNASPNVG++NP
Sbjct:  841 LDRQI-HTLNENISSLTKELETKGKEVLKIRSEANQQIRAHEQELMKRHERELSEMNAAHSRETQNMLSDFNKAQEVLKDKISALQILLEGTEEKFRNRESRPEDLQVIAELKDMVSERETLVKKLVDDKKFYQLELVNRETNFNKVFNASPNVGVINP 998          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Medaka
Match: zgc:85722 (protein FAM184A [Source:NCBI gene;Acc:105357787])

HSP 1 Score: 90.5077 bits (223), Expect = 7.622e-18
Identity = 50/189 (26.46%), Postives = 110/189 (58.20%), Query Frame = 3
Query:  219 KPHKNTLNGFKYTMDQDS-----LSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRI 770
            +P  ++ +  K+     S      ++DLH KMSKKIAQLTKVIYALNTKND++E  + +LK+ H  E+Q I+ ET +++   + KM    +  +++  L++++  +E +  +   +FE++++   +     + ++ ++   +++ +++++  +E+ L  +       E+EKR  +++L+  +  E++ +
Sbjct:    8 QPSFSSASAAKFIAPPPSGLTLEYTRDLHLKMSKKIAQLTKVIYALNTKNDEHEEEIESLKEAHEDEVQHIVTETRDKIMQYKTKMADEADLRRRLASLEESVELHEHMKRQALAEFEMYRQRMEDSQLCTEAQHTQRVVSMSREVEEMRRDFEEKLRAFSQAQAQFEAEKRRALDDLRATHRHEVEEL 196          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Medaka
Match: zgc:85722 (protein FAM184A [Source:NCBI gene;Acc:105357787])

HSP 1 Score: 90.5077 bits (223), Expect = 7.779e-18
Identity = 50/189 (26.46%), Postives = 110/189 (58.20%), Query Frame = 3
Query:  219 KPHKNTLNGFKYTMDQDS-----LSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRI 770
            +P  ++ +  K+     S      ++DLH KMSKKIAQLTKVIYALNTKND++E  + +LK+ H  E+Q I+ ET +++   + KM    +  +++  L++++  +E +  +   +FE++++   +     + ++ ++   +++ +++++  +E+ L  +       E+EKR  +++L+  +  E++ +
Sbjct:    8 QPSFSSASAAKFIAPPPSGLTLEYTRDLHLKMSKKIAQLTKVIYALNTKNDEHEEEIESLKEAHEDEVQHIVTETRDKIMQYKTKMADEADLRRRLASLEESVELHEHMKRQALAEFEMYRQRMEDSQLCTEAQHTQRVVSMSREVEEMRRDFEEKLRAFSQAQAQFEAEKRRALDDLRATHRHEVEEL 196          
BLAST of Family with sequence similarity 184 member A vs. Ensembl Medaka
Match: fam184b (trichohyalin [Source:NCBI gene;Acc:101174322])

HSP 1 Score: 65.0846 bits (157), Expect = 4.813e-10
Identity = 38/114 (33.33%), Postives = 62/114 (54.39%), Query Frame = 3
Query:  231 NTLNGFKYTM---DQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELF 563
            +T+NG    +   +Q+     +H KM KKIAQLTKVIY+LN +N+++E  L  L   H  E+ +IL ET +  EG   + +L         EL++++   + +  + +  FE F
Sbjct:   22 STVNGTAAELPNIEQELYDYQMHSKMCKKIAQLTKVIYSLNMRNEEHETALQALSHAHHDELHRILVETCHEGEGSALRTRLL--------ELQESLDEQQRVGAQVQADFEFF 127          
BLAST of Family with sequence similarity 184 member A vs. Planmine SMEST
Match: SMESG000058677.1 (SMESG000058677.1)

HSP 1 Score: 2041.54 bits (5288), Expect = 0.000e+0
Identity = 1093/1103 (99.09%), Postives = 1097/1103 (99.46%), Query Frame = 3
Query:  177 MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFNDQIRDLQTQLSEKANITIDEHKEEVRSLQRKISLLEEQSKTVTNTHRLELERVASAKLKLDCNYQNLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS 3485
            MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDET+NRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKE+NDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSK+DEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLV MKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLN SQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEV+SLQRKISLLEEQSK VTNTHRLELERVASAKLKLDCNYQ LEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIK NFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFV RPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAIKTKKINNDKIKSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS
Sbjct:    1 MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETNNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKELNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKMDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVIMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLNVSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEVKSLQRKISLLEEQSKAVTNTHRLELERVASAKLKLDCNYQKLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKRNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVNRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAIKTKKINNDKIKSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS 1103          
BLAST of Family with sequence similarity 184 member A vs. Planmine SMEST
Match: SMESG000058677.1 (SMESG000058677.1)

HSP 1 Score: 1982.22 bits (5134), Expect = 0.000e+0
Identity = 1066/1076 (99.07%), Postives = 1070/1076 (99.44%), Query Frame = 3
Query:  258 MDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFNDQIRDLQTQLSEKANITIDEHKEEVRSLQRKISLLEEQSKTVTNTHRLELERVASAKLKLDCNYQNLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS 3485
            MDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDET+NRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKE+NDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSK+DEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLV MKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLN SQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEV+SLQRKISLLEEQSK VTNTHRLELERVASAKLKLDCNYQ LEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIK NFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFV RPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAIKTKKINNDKIKSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS
Sbjct:    1 MDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETNNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKELNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKMDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVIMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLNVSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEVKSLQRKISLLEEQSKAVTNTHRLELERVASAKLKLDCNYQKLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKRNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVNRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAIKTKKINNDKIKSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS 1076          
BLAST of Family with sequence similarity 184 member A vs. Planmine SMEST
Match: SMESG000058677.1 (SMESG000058677.1)

HSP 1 Score: 1957.96 bits (5071), Expect = 0.000e+0
Identity = 1046/1056 (99.05%), Postives = 1050/1056 (99.43%), Query Frame = 3
Query:  177 MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFNDQIRDLQTQLSEKANITIDEHKEEVRSLQRKISLLEEQSKTVTNTHRLELERVASAKLKLDCNYQNLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGA 3344
            MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDET+NRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKE+NDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSK+DEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLV MKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLN SQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEV+SLQRKISLLEEQSK VTNTHRLELERVASAKLKLDCNYQ LEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIK NFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFV RPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGA
Sbjct:    1 MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETNNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKELNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKMDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVIMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLNVSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEVKSLQRKISLLEEQSKAVTNTHRLELERVASAKLKLDCNYQKLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKRNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVNRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGA 1056          
The following BLAST results are available for this feature:
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FAM184A3.103e-2332.03family with sequence similarity 184 member A [Sour... [more]
FAM184A5.104e-2332.03family with sequence similarity 184 member A [Sour... [more]
FAM184A5.741e-2331.30family with sequence similarity 184 member A [Sour... [more]
FAM184A7.562e-2332.03family with sequence similarity 184 member A [Sour... [more]
FAM184A9.404e-2037.50family with sequence similarity 184 member A [Sour... [more]
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BLAST of Family with sequence similarity 184 member A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Family with sequence similarity 184 member A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fam184a1.351e-2633.33family with sequence similarity 184 member A [Sour... [more]
fam184a7.014e-2624.30family with sequence similarity 184 member A [Sour... [more]
fam184a1.135e-2333.33family with sequence similarity 184 member A [Sour... [more]
zgc:857221.434e-1830.54zgc:85722 [Source:ZFIN;Acc:ZDB-GENE-040516-7][more]
fam184a1.103e-1227.70family with sequence similarity 184 member A [Sour... [more]
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BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ip6k29.133e-2434.25inositol hexaphosphate kinase 2 [Source:Xenbase;Ac... [more]
ip6k23.418e-2236.97inositol hexaphosphate kinase 2 [Source:Xenbase;Ac... [more]
ip6k21.278e-1924.01inositol hexaphosphate kinase 2 [Source:Xenbase;Ac... [more]
ENSXETT00000035830.12.425e-829.23protein FAM184B [Source:NCBI gene;Acc:100488800][more]
wdcp3.304e-721.86WD repeat and coiled coil containing [Source:Xenba... [more]
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BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Fam184a6.497e-1931.16family with sequence similarity 184, member A [Sou... [more]
Fam184a6.532e-1931.16family with sequence similarity 184, member A [Sou... [more]
Fam184a1.107e-1835.00family with sequence similarity 184, member A [Sou... [more]
Fam184a1.199e-1831.16family with sequence similarity 184, member A [Sou... [more]
Fam184a5.219e-1847.25family with sequence similarity 184, member A [Sou... [more]
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BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8NB25|F184A_HUMAN3.631e-2232.03Protein FAM184A OS=Homo sapiens OX=9606 GN=FAM184A... [more]
sp|Q9ULE4|F184B_HUMAN6.447e-1133.11Protein FAM184B OS=Homo sapiens OX=9606 GN=FAM184B... [more]
sp|Q60675|LAMA2_MOUSE2.541e-1020.81Laminin subunit alpha-2 OS=Mus musculus OX=10090 G... [more]
sp|Q0KK56|F184B_MOUSE3.949e-930.82Protein FAM184B OS=Mus musculus OX=10090 GN=Fam184... [more]
sp|P24043|LAMA2_HUMAN2.370e-821.90Laminin subunit alpha-2 OS=Homo sapiens OX=9606 GN... [more]
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BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3IWQ81.264e-6326.92protein FAM184A-like OS=Lingula unguis OX=7574 GN=... [more]
A0A2T7Q1881.924e-5725.15FAM184 domain-containing protein OS=Pomacea canali... [more]
V3ZZK52.136e-3528.08Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
R7V5R48.731e-3537.67Uncharacterized protein OS=Capitella teleta OX=283... [more]
A0A2G8L3Z47.814e-3425.82FAM184 domain-containing protein (Fragment) OS=Sti... [more]
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BLAST of Family with sequence similarity 184 member A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
fam184a1.466e-2723.00family with sequence similarity 184 member A [Sour... [more]
fam184a1.961e-2723.99family with sequence similarity 184 member A [Sour... [more]
fam184a1.630e-2133.33family with sequence similarity 184 member A [Sour... [more]
zgc:857223.440e-1929.08zgc:85722 [Source:ZFIN;Acc:ZDB-GENE-040516-7][more]
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BLAST of Family with sequence similarity 184 member A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
fam184a1.403e-1025.98family with sequence similarity 184 member A [Sour... [more]
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BLAST of Family with sequence similarity 184 member A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Family with sequence similarity 184 member A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Family with sequence similarity 184 member A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
fam184a1.575e-2437.74family with sequence similarity 184 member A [Sour... [more]
zgc:857227.622e-1826.46protein FAM184A [Source:NCBI gene;Acc:105357787][more]
zgc:857227.779e-1826.46protein FAM184A [Source:NCBI gene;Acc:105357787][more]
fam184b4.813e-1033.33trichohyalin [Source:NCBI gene;Acc:101174322][more]
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BLAST of Family with sequence similarity 184 member A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000058677.10.000e+099.09SMESG000058677.1[more]
SMESG000058677.10.000e+099.07SMESG000058677.1[more]
SMESG000058677.10.000e+099.05SMESG000058677.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004447 ID=SMED30004447|Name=Family with sequence similarity 184 member A|organism=Schmidtea mediterranea sexual|type=transcript|length=3498bp
ATTATGACTTGTGATTTTTATAATTGTATTTTGTTTTAAATACATGTTTA
ATATATTTATGGTTTATTGAAATATAAATAACTATATTTTAAAAACAGCT
TGTTTAAATCATTTAAAGTAGCTGTATCAATTTTAAATATATAGCAACTA
ATTTATTAATTTATATGATTTAATTTATGACTTCGACAACGAGTGATTAT
TTTCTAAATAACAATCAAAAACCTCATAAGAATACTTTGAATGGTTTCAA
ATATACTATGGACCAAGATTCTCTATCGCAGGATTTACATTTCAAGATGT
CAAAGAAAATCGCCCAATTGACCAAAGTTATTTATGCATTAAATACTAAA
AATGATGACAACGAAATGACATTAAACACGTTGAAGCAGCAACACAGCAA
AGAGATTCAGCAGATTCTGGATGAAACTAGTAACAGAGTAGAAGGGTTGC
AGAAAAAAATGAAATTAACTATTAATAATACCCAACAAATTCAAGAATTG
AAGCAAACGATTGCGTCATATGAAGATTTATTAACAGAAACAAAGCAGAA
ATTTGAATTGTTTCAAAAAGAAAGTAATGAAAGGACTAAAGAAAAAGATC
TAAAAAATGTCGAACAAACTCAGATGCTCAATCAAACTATAAAGGACCTA
AAATCATCATATGAGCAACTTCTTGATGATTACTACACTTTGAATACAAA
CATGGAATCAGAGAAAAGGTTGAAAATAGAAAATCTGAAAGTAGATTACG
AAAAGGAAATTCAGCGAATTACTGAAGAATGGAAAAATAAAGAGAAGCAA
TCAAAAGCTTTGATAGTGGGCAGTCAGAAAGAAATACAGATCCAGTTGGC
AGACGCCCAAGCAGAGATACAATCTCATATATATGCTAAAGACCAGCTAA
TTAAAGATCATGAAAGACAAATGAAGGAAATGAATGATTTATTTGATGCA
TTATCAGCGGAATCAAAAGAAAAAACTAAAAACTTTGAATTTGAAGTTGA
AGAATACAAATCAAGAATTTTCGAATACGGAAAGAATAGCATCCAGAAGG
AAAGTGAACTAAAAATTCAAGAAAATCAAATGAGAAAAGAATTAATAGAA
AAATCAACATTTATAAAGGATTTAGAATTAAAAATACAATCGTTAGAAAA
AGATTGTTTAGAAAAGGAGTCGAATATTTCAAAATTAAACATCGAAGTTT
CTCAACATAAAAGCACCATTGAAAGGTTAACATCCGAAATTAAATCAAGA
AATAATGAGTTACAGAGATTGCAAGATAGAAATGAAGAAAAAAGCAATGA
AATGGCATCTAAAATAAAACAAATAAAAGATTTAAAAAGTATAGCTGAAA
ATCTACAGCAAAAGTTTACTGAGAAGGAAAGAGAGTTAAAAAAAGCTTTG
ACAGAAATAAAAATAATGAATGAAGAATCTAAAGAAATGGCGAATTGTTC
CAAATCAGAGACGACTGATTACGTAATACAAATTCAAACTCTACAGCGGG
CTTTAGAGGAACTTAACAAAGAAAGACTCGAAGAAAAGTCAAGTATGGAA
AAACTAAAGCGATCTCATGAAATTGAATTGCTTGAATCAGTTGGAAGAAT
GAAAAAAGAATGCGAGTCAGATTTGGAGAAATCAAACAAAAAACGAGAAA
AAGAATTTGTATTGAAAGAAAAAAGCTTTCAAGATGAAATTCAAAAGCTT
AAAGAAGAGTTCCAGTCTAAATTGGACGAGGAACGATCAAAAGCGTCGAA
AATAATTGAAAAATTAAAATTTGATTTGGATCAGTTGAAGAATGATTTGA
ATATTAAAGTCAAGGGAAAAGATAAACAAATAATTAATTTGGAGGAAATT
ACCATAGGAAAGGACAAAGAAATTAAAACTCTTTCTCAACAGTTGAAAGA
AAATAAAGAGAACTTAGTTACAATGAAAAAAGATAATAATAGGTTAATGA
AGCTCAGTTCGGATAAGGATTCTGATATTGAAACTAATTTAAAAGAAATC
GACAGATTGAAGCTCAATTTGGAAGAACAAAAATCATTAAATGAAAATAT
TAGGAAAAACGTTCAAATTCAAGAAGACATGAGTGAAAAATATAATAAAC
TATCGGCTGAATTAGATATGAAATGGGCAGATACATTGCGCCGGGAAACT
GGAAGGTTGAGAAATGATATGTTAGAATCTTTTGCTAAAGAAAAGCAAAA
AGCAATCGAAATGGTAGAGAAAAAGAAAAATAATGAAATAGATCTTTTAA
CATTCAATTTTGAAGATCACAAGTCAAAAACGCAAAATGATTTATCGAAA
TACGAAACTGAAGTTGCAAAATTGAAAGAAGAAATAATTCATTTGAAAAA
ATTGAATGACAGCCAAATCACTGAAAAAATTCAAGAGGTACAACTATTAT
TGTCTGAGACTCAGATAATTCATGCAAAAGAGATTGAAAAATTGAAGAAT
TCCTACGATGTAAACATCCAAAATCTCAAAAAAAAATTCGAGGAAAATAA
ACTTCAGAGCGTGACTGAAACGCAGTCGCTAATAGAGTCACATGAAAGGG
CTTGGGCTGATAAACACCTAATTGAGATTAATTTATTAACAAATGAACAT
GAAAAAAAAATGAAAATGAAATTAGATGAAATGGAAAACAAATATGTCAA
ACAATTCAATGATCAAATTCGAGATTTACAAACACAATTATCCGAAAAGG
CAAATATTACAATTGATGAACATAAAGAAGAAGTGAGATCTTTACAAAGA
AAAATATCATTGCTAGAGGAACAGTCTAAAACAGTTACTAACACGCACCG
ACTGGAATTGGAACGGGTGGCATCGGCGAAATTGAAATTGGATTGTAATT
ATCAAAATTTAGAAAAACAATTACAGAACGCCATCAATGAAAATGCATAT
CTGAAAAAGCAAATTGATGATTTCGGAAACGATTACAGTCGAAGTCAACA
AGATTTCTCTGAAAAATTGAGATCCCAGGAGTCCGAAATCAAGCACAATT
TTGATCAGGTAATTCTCAATTTGAAAATGAAACATGAAGAAGAGACTAAA
CAAACAATAACTGACTTTAATAAAGCACAGAATCTCTATAAAGAAAAAAT
AAAAGAATTAAACAGCAGATTAATGGAAATTGACGAACAATTCGTTACTA
GGCCGGCTCGAGATGAAGATATTGAAATAATTCAAACGTTGACTGCTCAA
ACAAAATTGTACGAAAAAGAAATTGAAAGATTAAATGAAGAAAAGAGATT
TCTGCAATTAGAACTTGTTAACCGAGAAACCAATTTTAACAAAATTTTCA
ACGCATCCCCAAATGTTGGAATATTAAATCCAAATATGGGAGCAATTAAA
ACGAAGAAAATAAATAACGACAAAATCAAATCCTTTCAGAAACTCACTCC
ACTTCCTGGATCCCCATTTCACGATGATCCAATTAACCCAGCAAAGCCAT
TACCACCATCATCTAGAAAATCATTTGACAATTCTTAAATATTTGTAC
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protein sequence of SMED30004447-orf-1

>SMED30004447-orf-1 ID=SMED30004447-orf-1|Name=SMED30004447-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1104bp
MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTK
VIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTIN
NTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQM
LNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITE
EWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMK
EMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQEN
QMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIER
LTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEK
ERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKER
LEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKS
FQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDK
QIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMKLSSDKDSD
IETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKW
ADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKS
KTQNDLSKYETEVAKLKEEIIHLKKLNDSQITEKIQEVQLLLSETQIIHA
KEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIE
INLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHK
EEVRSLQRKISLLEEQSKTVTNTHRLELERVASAKLKLDCNYQNLEKQLQ
NAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLK
MKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIE
IIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGIL
NPNMGAIKTKKINNDKIKSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSF
DNS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR039478FAM184A/B_N
IPR029605FAM184
Vocabulary: molecular function
TermDefinition
GO:0003674molecular_function
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0005615extracellular space
Vocabulary: biological process
TermDefinition
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 105..132
NoneNo IPR availableCOILSCoilCoilcoord: 181..208
NoneNo IPR availableCOILSCoilCoilcoord: 1002..1036
NoneNo IPR availableCOILSCoilCoilcoord: 699..726
NoneNo IPR availableCOILSCoilCoilcoord: 429..463
NoneNo IPR availableCOILSCoilCoilcoord: 242..269
NoneNo IPR availableCOILSCoilCoilcoord: 878..912
NoneNo IPR availableCOILSCoilCoilcoord: 566..586
NoneNo IPR availableCOILSCoilCoilcoord: 601..635
NoneNo IPR availableCOILSCoilCoilcoord: 968..988
NoneNo IPR availableCOILSCoilCoilcoord: 313..417
NoneNo IPR availableCOILSCoilCoilcoord: 498..540
NoneNo IPR availableCOILSCoilCoilcoord: 74..101
NoneNo IPR availableCOILSCoilCoilcoord: 148..168
NoneNo IPR availableCOILSCoilCoilcoord: 750..770
NoneNo IPR availableCOILSCoilCoilcoord: 666..686
NoneNo IPR availableCOILSCoilCoilcoord: 824..873
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1072..1103
IPR039478Protein FAM184A/B, N-terminalPFAMPF15665FAM184coord: 51..253
e-value: 3.0E-25
score: 89.2
IPR029605FAM184 familyPANTHERPTHR18870FAMILY NOT NAMEDcoord: 33..1095