Family with sequence similarity 184 member A
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30004447 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Match: FAM184A (family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991]) HSP 1 Score: 108.612 bits (270), Expect = 3.103e-23 Identity = 74/231 (32.03%), Postives = 125/231 (54.11%), Query Frame = 3
Query: 2859 LEKQLQNAINEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
L+K++Q+ ++EN + L K+++ G + R + + ++++R E ++ ++ + + H E DFNK L KE L L E++E+++ R ++ EDI++I L A ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP N+ A+++ + N +L P+P SP HD N +KPL PP K+F
Sbjct: 766 LDKEVQH-LHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPN---RLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 992
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Match: FAM184A (family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991]) HSP 1 Score: 108.227 bits (269), Expect = 5.104e-23 Identity = 74/231 (32.03%), Postives = 125/231 (54.11%), Query Frame = 3
Query: 2859 LEKQLQNAINEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
L+K++Q+ ++EN + L K+++ G + R + + ++++R E ++ ++ + + H E DFNK L KE L L E++E+++ R ++ EDI++I L A ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP N+ A+++ + N +L P+P SP HD N +KPL PP K+F
Sbjct: 844 LDKEVQH-LHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPN---RLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 1070
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Match: FAM184A (family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991]) HSP 1 Score: 101.679 bits (252), Expect = 5.741e-23 Identity = 72/230 (31.30%), Postives = 121/230 (52.61%), Query Frame = 3
Query: 2859 LEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
L+K++Q+ + L K+++ G + R + + ++++R E ++ ++ + + H E DFNK L KE L L E++E+++ R ++ EDI++I L A ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP N+ A+++ + N +L P+P SP HD N +KPL PP K+F
Sbjct: 38 LDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHP---NRLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 264
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Match: FAM184A (family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991]) HSP 1 Score: 107.457 bits (267), Expect = 7.562e-23 Identity = 74/231 (32.03%), Postives = 125/231 (54.11%), Query Frame = 3
Query: 2859 LEKQLQNAINEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
L+K++Q+ ++EN + L K+++ G + R + + ++++R E ++ ++ + + H E DFNK L KE L L E++E+++ R ++ EDI++I L A ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP N+ A+++ + N +L P+P SP HD N +KPL PP K+F
Sbjct: 886 LDKEVQH-LHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPN---RLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 1112
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Match: FAM184A (family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991]) HSP 1 Score: 97.4413 bits (241), Expect = 9.404e-20 Identity = 54/144 (37.50%), Postives = 82/144 (56.94%), Query Frame = 3
Query: 3117 RLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
RL E++E+++ R ++ EDI++I L A ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP N+ A+++ + N +L P+P SP HD N +KPL PP K+F
Sbjct: 803 RLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPN---RLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 943
BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Match: fam184a (family with sequence similarity 184 member A [Source:ZFIN;Acc:ZDB-GENE-041014-214]) HSP 1 Score: 111.309 bits (277), Expect = 1.351e-26 Identity = 70/210 (33.33%), Postives = 112/210 (53.33%), Query Frame = 3
Query: 2883 INEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP-------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL 3452
+NEN + L K+++ G + + + + ++++R+ E ++ ++ + L H ET+ ++DFNKAQ L K+KI L L +++F R +R ED++ I L E +++L ++K+F QLELVNRET+FNKIFNA+PNVG++NP N+ A +L PLP SP H N +KPL
Sbjct: 40 LNENISTLTKELELKGKEVLKIRSEANQQIRAHEQDLCKKHEREMAELNALHHRETQNMLSDFNKAQELLKDKISALQILLEGTEDKFRNRESRPEDLQTIAELKDMVAEREALVKKLVDDKKFYQLELVNRETSFNKIFNANPNVGVINPLVKQKRKNDKSATRFSSSANLRANVEASGTGSGQPQPNRLEPLPNSPIHQLEPNASKPL 249
BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Match: fam184a (family with sequence similarity 184 member A [Source:ZFIN;Acc:ZDB-GENE-041014-214]) HSP 1 Score: 116.701 bits (291), Expect = 7.014e-26 Identity = 164/675 (24.30%), Postives = 346/675 (51.26%), Query Frame = 3
Query: 276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAE-----IQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFE-VEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNN--ELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTD--YVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKE--------EFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLM-KLSSDKDSDIET-NLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEI 2240
+QDLH KMSKKIAQLTKVIYALNTKND++E + TLK+ H +E+QQIL ET ++ + K+ ++ ++IQ L++++ +E + + +FE +++ + + ++ ++ +++ +++++ S+E+ L + L + E EKR +E L+ + +E+Q + + QS+ +E QL A+ + ++ K +L++++E ++ + ++ E+ ++T+ E + +K E K +E+ L+ ++R EL ++ K L+ + E+NI +L+ ++ + E EI+ R EL+ +DR ++++ E+ K QI L+ A + + ++ E +K+ + K++ E + A +K +T D QI TL++ S+ + K+ +E EL+ + + + + ++S+ + +E K ++ + IQ L E + + + ++ER+ + L+ +LD L+ +L K+ + ++ L+E+ +K Q L ++ ++ +K +L+ +L + + ET NL + L+ +E QK ++ K + I+E+ K +K++ EL++KW +TLR+E +LR ++ E ++K+ A+ + + K+ E+
Sbjct: 44 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALDEFETYRQRVEDMQLCTEAQHTQRVVSMSREVEEMRRSFEEKLRSFAQLQSQFEQEKRQALEELRSGHRQEVQELL-----RSHQSQNANYSKDQEKLGQLHKAEVDSLNERVEELKQDKKRLVEEYEAKLNKAQAFYER-ELEAMKRTQQMTAENLLAWKKTEAELRKEFQAQEAALQKTLGKLRSELQRVQDEARESREKSHKLQASLMTAENNIKELHKQLEEVTKDAE--IVEIRQREGECELEASRDRVQQQATEILLKASQIGSLQ--ATQMTHEAVIRDLESEKSRLKDKVLRLEEERGALQNKCQTLDDRQRQQIVTLEK--------------SLREEKQIYEKELMNLRAKYEDDT-AHFKESHSRALEELSRKHRASLENIQSLSEKEKNRLLSDMEDQFNKERTSLEEQKRILREELDSLREELTAKLNMANNEVSRLQEL-------VKQGEQTLGSSEGHISNLKDAQKKLLEELDATRARLRETSNL--LTALQGEMETQKQQHDA--KLISIKEEEKLKMDKMALELELKWTETLRQECKKLREELREDHEEDKRSALTQLAQNKDQEL 682
BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Match: fam184a (family with sequence similarity 184 member A [Source:ZFIN;Acc:ZDB-GENE-041014-214]) HSP 1 Score: 105.145 bits (261), Expect = 1.135e-23 Identity = 60/180 (33.33%), Postives = 112/180 (62.22%), Query Frame = 3
Query: 234 TLNGFK-YTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRI 770
T G++ Y S +QDLH KMSKKIAQLTKVIYALNTKND++E + TLK+ H +E+QQIL ET ++ + K+ ++ ++IQ L++++ +E + + +FE +++ + + ++ ++ +++ +++++ S+E+ L + L + E EKR +E L+ + +E+Q +
Sbjct: 3 TGAGWQHYYNPAGSYTQDLHLKMSKKIAQLTKVIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALDEFETYRQRVEDMQLCTEAQHTQRVVSMSREVEEMRRSFEEKLRSFAQLQSQFEQEKRQALEELRSGHRQEVQEL 182
BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Match: zgc:85722 (zgc:85722 [Source:ZFIN;Acc:ZDB-GENE-040516-7]) HSP 1 Score: 92.8189 bits (229), Expect = 1.434e-18 Identity = 51/167 (30.54%), Postives = 105/167 (62.87%), Query Frame = 3
Query: 276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITE 776
+QDLH KMSKKIAQLTKVIYALNTKND++E + +LK+ H +E+Q IL ET ++ + K+ + +++Q L++++ +E + + +FE++++ + + ++ ++ +++ +++++ +E+ L + + E EKR +++LK + +E++ + E
Sbjct: 54 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEDAIQSLKEAHDEEVQHILTETREKILHYKSKIGDEADLKRRLQSLEESVELHEHMKRQALAEFEMYRQRMEDTQLCTEAQHTQRVVSMSREVEEMRHEFEEKLRTFSQVQAQFEQEKRHALDDLKSAHRQEVEDLLE 220
BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Match: fam184a (family with sequence similarity 184 member A [Source:ZFIN;Acc:ZDB-GENE-041014-214]) HSP 1 Score: 73.9442 bits (180), Expect = 1.103e-12 Identity = 41/148 (27.70%), Postives = 90/148 (60.81%), Query Frame = 3
Query: 327 VIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRI 770
VIYALNTKND++E + TLK+ H +E+QQIL ET ++ + K+ ++ ++IQ L++++ +E + + +FE +++ + + ++ ++ +++ +++++ S+E+ L + L + E EKR +E L+ + +E+Q +
Sbjct: 1 VIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALDEFETYRQRVEDMQLCTEAQHTQRVVSMSREVEEMRRSFEEKLRSFAQLQSQFEQEKRQALEELRSGHRQEVQEL 148
BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Match: ip6k2 (inositol hexaphosphate kinase 2 [Source:Xenbase;Acc:XB-GENE-971466]) HSP 1 Score: 110.538 bits (275), Expect = 9.133e-24 Identity = 75/219 (34.25%), Postives = 119/219 (54.34%), Query Frame = 3
Query: 2859 LEKQLQNAINENA-YLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILN-------------------PNMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLP 3455
L KQL A+ EN L K++D G + + + ++++R QE ++ + + +L H E + I + K Q L+ EK L L E++E++ R +R ED++II L ++ I++L ++K+F QLELVNRETNFNK+FNASPNVG++N PN+ A+++ + N +L P+P SP HD + +KPLP
Sbjct: 891 LNKQLM-ALKENINSLTKELDFKGKEILCIRSEANQQIRVQEQDLNKKHKEDLNDLTSAHIREKQILIAEMAKTQALFMEKNSALQKSLTEMEEKYQNRESRPEDLQIISELKEMVTERDQLIKKLIDDKKFYQLELVNRETNFNKVFNASPNVGVINPLVKQKKKNDKSTNRFVSVPNLSALESGGMGNGHPP---RLDPIPNSPIHDIEFSSSKPLP 1105
BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Match: ip6k2 (inositol hexaphosphate kinase 2 [Source:Xenbase;Acc:XB-GENE-971466]) HSP 1 Score: 105.531 bits (262), Expect = 3.418e-22 Identity = 61/165 (36.97%), Postives = 91/165 (55.15%), Query Frame = 3
Query: 3018 NLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILN-------------------PNMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLP 3455
+L H E + I + K Q L+ EK L L E++E++ R +R ED++II L ++ I++L ++K+F QLELVNRETNFNK+FNASPNVG++N PN+ A+++ + N +L P+P SP HD + +KPLP
Sbjct: 922 DLTSAHIREKQILIAEMAKTQALFMEKNSALQKSLTEMEEKYQNRESRPEDLQIISELKEMVTERDQLIKKLIDDKKFYQLELVNRETNFNKVFNASPNVGVINPLVKQKKKNDKSTNRFVSVPNLSALESGGMGNGHPP---RLDPIPNSPIHDIEFSSSKPLP 1083
BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Match: ip6k2 (inositol hexaphosphate kinase 2 [Source:Xenbase;Acc:XB-GENE-971466]) HSP 1 Score: 97.0561 bits (240), Expect = 1.278e-19 Identity = 164/683 (24.01%), Postives = 352/683 (51.54%), Query Frame = 3
Query: 276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQ---IQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYK-SRIF--EYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKI-----QSLEKDC--LEKESNISKLNIEVSQHK-STIERLTSEIKSRNN----ELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECES-DLEKSNKKREKEFVLKEKSFQDEIQ-------KLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMK-LSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEID 2243
+ +LH KMSKKIAQLTKVIYALNTKND++E + +K+ H +EIQ+IL ET ++ + K+ + +I+ L++++ ++ + +FE+++ + + ++V++ +++ +++++ +++ + ++ + E +KR +++L+ EIQ + K + Q+ L G + ++ +Q+ D +I+ + +L++D+E ++ + +E E+E K S++F E QKE+E+K ++ Q ++ L++K+ I E ++ +L + C L+ N ++ NI+V Q + +++ + S+ N EL ++R ++++ E+ K I L+ A ++ Q+ T ++ E +KA + KI E + SK++ D +R +++ + + + + +E EL+ R+K E E+ L++ + K +E LK ++ + Q KL+ E Q + ++E S+ + L+ L+ LK DL K+ +++ + L+++ +K Q L + ++ ++K NRL K L ++ ETN + ++ LE+++ +E I ++ +E + K +K++ +L++KW +TLR+E ++R ++ A++K+ AI + + K EI+
Sbjct: 44 TAELHLKMSKKIAQLTKVIYALNTKNDEHESGIQAIKEAHEEEIQKILAETHEKILLYKNKVSEETDLKHKIKALEESLEEHKKMKHHALTEFEVYKHRVEDMQLCAEAQHVQRIVTMSREVEEMRKKFDERIHNFMQIQVQFEKDKRSALDDLRTS-RLEIQEL---LKAQHNQNATLNKGQETLLEMHRLQVEDLNKKIEDMRLERKRLVEDYEAKLTKAQAF--------------YEHEMEALKRSQMFTAESLHACKQKEAEIK-KDFQSQEALLQKNLGILKTEFQVVQEEAVNLREKCQKLQISLNTAETNIQVLQKQLENVKQGEMSLLSKQNDMESELAAARERIQQQATELVLKASHIGMLQ--ATHMTQEATIQDLESEKARIKEKIARLEEERTLLQSKNQNLD--------ERQRQQMVALERKINEAKQTQRECYEKELINL--RIKFEEETMQLKEFHTKTVEEMSLKHQAALEAAQSTANKEKKLQMELQQQFEKEISELEESKNHLRQQLENLKEDLTEKLTSANQENVQLQDL-------VKKSEQGLGSAECHITSLKDAQNRLQKELDLTRERLRETN-DSLFAVQEELEKERQQHEVILNAIREEERL--KMDKVARDLELKWTETLRQECSKVREELKLQHAEDKKSAIAQLLQLKEREIN 685
BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Match: ENSXETT00000035830.1 (protein FAM184B [Source:NCBI gene;Acc:100488800]) HSP 1 Score: 59.6918 bits (143), Expect = 2.425e-8 Identity = 57/195 (29.23%), Postives = 100/195 (51.28%), Query Frame = 3
Query: 210 NNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYE----QLLDDYYTLNTNMESEKRLK-IENLKVDYEKEIQRITEE 779
N+Q N G + Q + +LH KM KKIAQLTKVIYALN K D+ E + +LK+ H EI I ET + + K+ + Q+IQ L++++ + +T F ++++ E ++ E+ +L++ + +K+ +E QL D+ +L ++ +R K +E L E+Q +++E
Sbjct: 6 NHQHSQYNGTKGQQMLFSQ-AYPHELHGKMCKKIAQLTKVIYALNLKVDEYEYNILSLKEAHQDEIDLISSETKEKFLQYESKIGEEQHLRQRIQSLEESLEKNNMIKEQTLADFAKYKRQMEEWESRTKAEHNERISVLSKEMLSMKTDFETKVKQLTDEADSLRKECKASERDKAMETLNEKLNAEVQTLSQE 199
BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Match: wdcp (WD repeat and coiled coil containing [Source:Xenbase;Acc:XB-GENE-5729803]) HSP 1 Score: 56.6102 bits (135), Expect = 3.304e-7 Identity = 122/558 (21.86%), Postives = 236/558 (42.29%), Query Frame = 3
Query: 486 QIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKE-KQSKALIVGSQ------KEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKE-MNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQ---KESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNI---SKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLES-VGRMKKECESDLEKS-----NKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKD---NNRLMKLS----SDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNV-QIQE 2075
Q QELK LL+ + L Q N +D +E ++LN+ K + + EQ D N E K+L+ D+ KE R +++ +K K ++ L + ++ +E+Q + AE++ + D E + E + + L E+ +K ++ EV+E K +FE + + +E+ KI+ + +K+ + +LE K Q +EK E ES + + EV+ I +++ N EL L ++ EK N + +I + +L ++ + E + + + +++ E N S + T + + + + E+ + K K + I+L+ G +K E ++ ++KS + KR V K ++++ +K ++ DE+ + + L + ND +K++ + + + +K L+ L K+N +K+D N +K +D D ++ KE DRL L+ K L EN+ KN+ QI+E
Sbjct: 1417 QTQELKH-------LLSPQRAPERLLQLAQNN----QDTLVIEMDELLNRAAK-VTADGEQTGKDAERTN---ERAKQLE------DFVKETLRASKDIYDKAVKLNETLGIPNKTLDKSFQELQKDIDSMMAELRRKSLRNQKNTADDELKAAEALLNRVKKLFLEAHKKNEDLNNEVKE-KLGLFEEKLDDVWDLLREARGKIKAADDLSTVNQKN--MTELERKKQGVEKGKKETESVLGDGDSIMTEVNNLAQIINEAENDLSDMNKELPPLTEQLNEKINNLTQEIAR--------RDLPEQILQAENQAAQLIDSSAVLDGILAEAKNLSFNATVAFN------AYSNIKDLIDDAEDTAKEAKAKANEAIDLVTGPQGSLKDEAKNAIQKSFRVLSDAKRHSGDV---KDNENDLAGIKNRLENA-DEKNQNMLQALNDTFGKLALIPNDTLVKIQTAKDKAKQANDTASDVLERLKDLNLNLLGLKQNYTALKEDVAKTNAAVKDPVENITDADGRVKQLEKEADRLLDKLKPIKELQENLGKNISQIKE 1932
BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Match: Fam184a (family with sequence similarity 184, member A [Source:MGI Symbol;Acc:MGI:1923156]) HSP 1 Score: 92.8189 bits (229), Expect = 6.497e-19 Identity = 67/215 (31.16%), Postives = 115/215 (53.49%), Query Frame = 3
Query: 2856 NLEKQLQNAINENA-YLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPIN 3437
+L+K++Q+ ++EN L K+++ G + R + + ++++R E ++ ++ + + H E DFNK L KE L L +++E+++ R +R EDI++I L + ++ I++L E+ +F QLELVNRETNFNKIFN SP VG++NP N+ A+++ + N +L P+P SP HD N
Sbjct: 285 DLDKEVQH-LHENINTLTKELELKGKEILRVRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDIQMIAELKSLITERDQVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINPLAKQKKKNDKSAANRFVSVPNLSALESSGMGNGHPT---RLEPIPNSPAHDVEFN 495
BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Match: Fam184a (family with sequence similarity 184, member A [Source:MGI Symbol;Acc:MGI:1923156]) HSP 1 Score: 91.2781 bits (225), Expect = 6.532e-19 Identity = 67/215 (31.16%), Postives = 115/215 (53.49%), Query Frame = 3
Query: 2856 NLEKQLQNAINENA-YLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPIN 3437
+L+K++Q+ ++EN L K+++ G + R + + ++++R E ++ ++ + + H E DFNK L KE L L +++E+++ R +R EDI++I L + ++ I++L E+ +F QLELVNRETNFNKIFN SP VG++NP N+ A+++ + N +L P+P SP HD N
Sbjct: 141 DLDKEVQH-LHENINTLTKELELKGKEILRVRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDIQMIAELKSLITERDQVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINPLAKQKKKNDKSAANRFVSVPNLSALESSGMGNGHPT---RLEPIPNSPAHDVEFN 351
BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Match: Fam184a (family with sequence similarity 184, member A [Source:MGI Symbol;Acc:MGI:1923156]) HSP 1 Score: 88.5817 bits (218), Expect = 1.107e-18 Identity = 56/160 (35.00%), Postives = 97/160 (60.62%), Query Frame = 3
Query: 2856 NLEKQLQNAINENA-YLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP 3332
+L+K++Q+ ++EN L K+++ G + R + + ++++R E ++ ++ + + H E DFNK L KE L L +++E+++ R +R EDI++I L + ++ I++L E+ +F QLELVNRETNFNKIFN SP VG++NP
Sbjct: 111 DLDKEVQH-LHENINTLTKELELKGKEILRVRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDIQMIAELKSLITERDQVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINP 269
BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Match: Fam184a (family with sequence similarity 184, member A [Source:MGI Symbol;Acc:MGI:1923156]) HSP 1 Score: 93.5893 bits (231), Expect = 1.199e-18 Identity = 67/215 (31.16%), Postives = 115/215 (53.49%), Query Frame = 3
Query: 2856 NLEKQLQNAINENA-YLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPIN 3437
+L+K++Q+ ++EN L K+++ G + R + + ++++R E ++ ++ + + H E DFNK L KE L L +++E+++ R +R EDI++I L + ++ I++L E+ +F QLELVNRETNFNKIFN SP VG++NP N+ A+++ + N +L P+P SP HD N
Sbjct: 888 DLDKEVQH-LHENINTLTKELELKGKEILRVRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDIQMIAELKSLITERDQVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINPLAKQKKKNDKSAANRFVSVPNLSALESSGMGNGHPT---RLEPIPNSPAHDVEFN 1098
BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Match: Fam184a (family with sequence similarity 184, member A [Source:MGI Symbol;Acc:MGI:1923156]) HSP 1 Score: 83.5741 bits (205), Expect = 5.219e-18 Identity = 43/91 (47.25%), Postives = 61/91 (67.03%), Query Frame = 3
Query: 3060 TDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP 3332
DFNK L KE L L +++E+++ R +R EDI++I L + ++ I++L E+ +F QLELVNRETNFNKIFN SP VG++NP
Sbjct: 14 ADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDIQMIAELKSLITERDQVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINP 104
BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Match: sp|Q8NB25|F184A_HUMAN (Protein FAM184A OS=Homo sapiens OX=9606 GN=FAM184A PE=1 SV=3) HSP 1 Score: 107.457 bits (267), Expect = 3.631e-22 Identity = 74/231 (32.03%), Postives = 125/231 (54.11%), Query Frame = 3
Query: 2859 LEKQLQNAINEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP--------------------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPL----PPSSRKSF 3476
L+K++Q+ ++EN + L K+++ G + R + + ++++R E ++ ++ + + H E DFNK L KE L L E++E+++ R ++ EDI++I L A ++ I++L E+ +F QLELVNRETNFNK+FN+SP VG++NP N+ A+++ + N +L P+P SP HD N +KPL PP K+F
Sbjct: 886 LDKEVQH-LHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPN---RLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTF 1112
BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Match: sp|Q9ULE4|F184B_HUMAN (Protein FAM184B OS=Homo sapiens OX=9606 GN=FAM184B PE=2 SV=3) HSP 1 Score: 70.8626 bits (172), Expect = 6.447e-11 Identity = 49/148 (33.11%), Postives = 81/148 (54.73%), Query Frame = 3
Query: 240 NGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRV---EGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLL 674
G + MD D +H KM KKIAQLTKVIYALNT+ D+ E ++ L++ H +E+Q + ET R+ +G ++ L Q+IQ L+ + + L E + + E+ ER + ++ E+ L++ + +LK+ YE+ L
Sbjct: 22 GGAGWRMDCDP---QMHVKMCKKIAQLTKVIYALNTRQDEAEASMEALREAHQEELQNAVAETKARLLQEQGCAEEEAL----LQRIQALESALELQKRLTEEALAESASCRLETKERELRVEAEHAERVLTLSREMLELKADYERRL 162 HSP 2 Score: 58.5362 bits (140), Expect = 3.816e-7 Identity = 44/156 (28.21%), Postives = 83/156 (53.21%), Query Frame = 3
Query: 2889 ENAYLKKQIDDFGNDYSRSQQDFSEKLRSQ----ESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKE--IERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNM 3338
ENA L+ + + + QQ+ ++KLR Q E + + + L+ +H +E + + DF+ AQ + ++ L + L + E+ +R ED+++I L QT+L E+E I++L EE+RF + ++ N+ F+ +P+ G L P+M
Sbjct: 810 ENAQLQDAVRRLRAEVEQHQQE-AQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQAQLQARLAALEAELKDSGEKPGKGASRPEDLQLIGRL--QTRLKEREDIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSM 962
BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Match: sp|Q60675|LAMA2_MOUSE (Laminin subunit alpha-2 OS=Mus musculus OX=10090 GN=Lama2 PE=1 SV=2) HSP 1 Score: 69.3218 bits (168), Expect = 2.541e-10 Identity = 118/567 (20.81%), Postives = 250/567 (44.09%), Query Frame = 3
Query: 474 NNTQQIQELKQTIASYEDLLTETKQKFELFQKESNE----RTK-----EKDLKNVEQT----QMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSK-----SETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECESDLEKSNK--KREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLK---NDLNIK---VKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMK------LSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNV-QIQE 2075
N TQ+++ L + E L+ + E+NE TK E+ ++ E+T + L + IK L E + + LN + ++ + NL+ + +KEI R+ +E ++K+ Q+ QKE+ A+D+L+ E +K +N LF A++++ K+ + ++ EYK+++ + + +E+ K ++ +K+ I LE K +++E + E+ + + N + + + + S I ++ +L +EE S+++ ++IKD + +AE + Q + + + I++E N + S DY+ + + + R +EL + + +S + G +K++ + L+KS + K+ K +++ LK ++L+ + S ++ L +D+L ND K VK K ++ + + + + K++ LK+N L N ++K + +D + + +E DRL L+ K L +N++KN+ +I+E
Sbjct: 1610 NTTQELKHLLSPQRAPERLIQLAEGNVNTLVMETNELLTRATKVTADGEQTGQDAERTNSRAESLEEFIKGLVQDAEAINEKAVQLNETLGNQDKTAERNLE-ELQKEIDRMLKELRSKDLQT-------QKEV----------------AEDELVA-AEGLLKRVNKLFGEPRAQNEDMEKDLQQKLAEYKNKLDDAW--DLLREATDKTRDANRLSAANQKNMTI--LETKKEAIEGSKRQIENTLKEGNDILDEANRLLGEINSVIDYVDDIKTKLPPMSEELSDKIDDLAQEIKD-RRLAEKVFQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFRAYSNIKDYIDEAEKVAREAKELAQGATKLATSPQ--------------GLLKEDAKGSLQKSFRILNEAKKLANDVKGNHNDLNDLK----TRLETADLRNSGLLGALNDTMDKLSAITNDTAAKLQAVKEKAREANDTAKAVLAQVKDLHQNLDGLKQNYNKLADSVAKTNAVVKDPSKNKIIADAGTSVRNLEQEADRLIDKLKPIKELEDNLKKNISEIKE 2128
BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Match: sp|Q0KK56|F184B_MOUSE (Protein FAM184B OS=Mus musculus OX=10090 GN=Fam184b PE=2 SV=1) HSP 1 Score: 65.0846 bits (157), Expect = 3.949e-9 Identity = 45/146 (30.82%), Postives = 81/146 (55.48%), Query Frame = 3
Query: 240 NGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINN-TQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLL 674
G + MD D ++H KM KKIAQLTKVIYALNT+ D+ E+++ ++++ H +++Q ET R+ Q + ++IQ L+ + + L E + + E+ ER + ++ E+ +L++ + +LK+ YE+ L
Sbjct: 24 GGSGWRMDCDP---EMHVKMCKKIAQLTKVIYALNTRQDEVEVSVESIREAHQEDLQDTGAETRTRLPQEQSRTSEDAETLLKRIQTLENALELQKRLTQEALAESASCKLETKERELRVEAEHAERVLILSKEMLELKADYEKRL 166 HSP 2 Score: 58.9214 bits (141), Expect = 2.976e-7 Identity = 34/108 (31.48%), Postives = 61/108 (56.48%), Query Frame = 3
Query: 3021 LKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKE--IERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNM 3338
L+ +H +E + + DF+ AQ + ++ L + L E E+ +R ED+++I L QT+L E+E I +L EE+RF + ++ N+ F+ +P+ G L P+M
Sbjct: 739 LRQEHRKEMQAMVADFSGAQARLQARLAALETELKESGEKAGKGTSRPEDLQLIGRL--QTRLKEREDIIRQLTEERRFHYAAFPSAVSHRNRSFSFNPHPGYLTPSM 844
BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Match: sp|P24043|LAMA2_HUMAN (Laminin subunit alpha-2 OS=Homo sapiens OX=9606 GN=LAMA2 PE=1 SV=4) HSP 1 Score: 62.7734 bits (151), Expect = 2.370e-8 Identity = 127/580 (21.90%), Postives = 242/580 (41.72%), Query Frame = 3
Query: 474 NNTQQIQELKQTIASYEDLLTETKQKFELFQKESNE----RTK-----EKDLKNVEQT----QMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKI----KQIKDLK-----SIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLES--VGRMKKECESDLEKSNK--KREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIK---VKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLM----------------KLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNV-QIQE 2075
N TQ+++ L + E L+ + E NE TK E+ ++ E+T + L + IK+L E + + LN + + NL+ +KEI ++ +E + K ++ QKEI A+D+L+ E +K++ LF E++E K+ ++ +YK+++ + + +E+ KI+E + +K+ + LE K +++E + E+ + + N + + RL EI S + ++ +Q + S E+ KI ++IKD K S AE+ + + L L E K ++ + A + S DY+ + + + + E +HE L + G +K++ + L+KS + K+ K +D + LK ++ D + + L + ND K VK K +Q + K + Q+ E +NL +KK+ N+L K+ +D D+ ++ +E DRL L+ K L +N++KN+ +I+E
Sbjct: 1614 NMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLE-GLQKEIDQMIKELRRKNLET-------QKEI----------------AEDELVA-AEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAW--DLLREATDKIREANRLFAVNQKN--MTALEKKKEAVESGKRQIENTLKEGNDILDE----ANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATA-AFKAYSNIKDYIDEAEKVAK----------------EAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENA-DARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQ----------ANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKE 2132
BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Match: A0A1S3IWQ8 (protein FAM184A-like OS=Lingula unguis OX=7574 GN=LOC106168200 PE=4 SV=1) HSP 1 Score: 247.284 bits (630), Expect = 1.264e-63 Identity = 312/1159 (26.92%), Postives = 586/1159 (50.56%), Query Frame = 3
Query: 240 NGFKYTMDQDS-----LSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQK-------FELFQKESNERTKEKDLKNVEQTQM--LNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQI----QLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEY--GKNSIQKESELKIQENQMRK---ELIEKSTFIKDLELK----IQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEM-----------ASKIKQ---IKDLKSIAENLQQK--FTEKERELKKALTEIKIMNEESK--EMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEK-LKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRL-MKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFNDQIRD--LQTQ----LSEKANITIDEHKEEVRSLQRKISLLEEQSK---TVTNTHRLELER-------------VASAKLKLDCNYQ-----NLE---KQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNM---GAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSF 3476
NG T+ Q + ++QD+H KMSKKIAQLTKVIYALNTKND++E + ++K H +E+QQ++ ET ++E + +M + ELK+ I + E L E +Q+ F+ F++ + ER E LK E ++ L+Q + +K +E+ L + + + ES +R +ENLK + KE+ E+ +N + ++ + ++ ++ Q+ + +I+ K ++ D+E ++ + +D + +N + E SRI + +N I+K+ QE Q +K +LIE+ + +D K +Q+ EK ++ S+ L+ ++S K + + +K EL ++R E++ +M A++++ IKDL+S L+ + + EKERE L + EE K ++ + +S D ++ Q L+ E E + EK L+ +HE E++E + +M KE E + K+ + I +LK+E Q K++ + + ++ I +K + ++++ DL+ K+K ++++ LE++ +K Q L ++ ++K+ +++L +L S K +++ + L+ LE+ +++++ + Q+ ++ K ++LS +LD KW DTLR+E +LR+++ E ++K+ A++ + K K+ EI +E ++ +++S + + E L + + + ++ ++E +AK++E L+ + I+NL+ Q + E +E ER KH+ E++ +K + + VK D+ RD L+TQ LSEK + K E+ R LE+ +K T N R+ELER + S +L+ + ++ NLE +Q+Q +++ ++++++ G + + + + +++LR +E ++ ++ + +L H ET+ + +FN+AQ+L K+KI L L E ++ + R +R ED+E+I+ L + E+ ++RL +EK++ QLELVNRETNFNK+FN PNVG+LNP M S +L PLPGSP H++ +NP KPLPP++ K F
Sbjct: 14 NGKYGTLPQTNPKDAEITQDMHLKMSKKIAQLTKVIYALNTKNDEHEAVIQSIKDHHEEEMQQLITETRVKLENYRTRMGGDV-------ELKKKITALEALNAEHQQQKQQALEDFQNFKRRAEER--EMQLKTEESQKVIQLSQEVLTIKKHFEEQLSKFDQVKADFESNQRTALENLKKVHAKEL----EDLRNAQSSQQSDLSKERERLEQLYSQQIDQLKGQIEELNGDKKKIADDYEDKLSKAKAFYDK-ELDVLRNAQNSDME-----SRISDLLAQQNKIKKD--FAYQEGQFKKRIDDLIEQLSRSEDEIAKQKEQLQNYEKMIQDRSSDSDTLSRQLSDAKHETAQAITRLKEVEGELAASKERCSEQAADMLKKSTLLGQLEATRLQNEATIKDLESQLSKLKDRSAWLEKERE---GLQNKTLSQEEEKNHQLKSLERS-LEDLSLEKQALKERYERDLNSLEESHAKREKELQNNHEAEMME-LKKMHKE--------------ELENQRKASTEMITQLKKENQDKIEALQKQHNEEITSMKAEYERVQGDLSHKLKTAEEEVRRLEKL-------VKESEQGLGSASSHIDSLKEASDKLKAELDSTK-AELRAVSNQKSNLQAELEKLRAMHDTKMREAQL--ELKTKLDQLSKDLDAKWTDTLRKECLKLRSELTEQKEEDKRAALQQLAKMKDEEIAAAREGWERKVTQLLDEISMLKRNIDAKSSESSELLADLKQKAAAEEKRLRDQMNEAADEYAKKVEALERIHAEKIKNLE-------AQRIKE----VEEMERTLTSKHMEEMS---------NTIKAQKALIESVKDQADKQRDQDLETQHKIHLSEKETL-----KSEL--AHRHAMELEQMNKAHNTQMNAARMELERAIELSKQKERDFEIRSTELQEEVRHREKHISNLEAEIRQVQEGLDQ---MRREVEFKGKEILKIRSEANQQLRKREEQLAQQHEEQVNSLSADHLRETQDMLGEFNRAQDLLKDKISALQIMLEEAEDNYRNRESRPEDLEMIKQLQKALEDREEYMKRLEDEKKYYQLELVNRETNFNKVFNTQPNVGVLNPFMKPKKKGDKGPTKYTSSPSLNRLQPLPGSPVHEEKLNPIKPLPPTAVKKF 1092
BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Match: A0A2T7Q188 (FAM184 domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_02058 PE=4 SV=1) HSP 1 Score: 228.409 bits (581), Expect = 1.924e-57 Identity = 287/1141 (25.15%), Postives = 550/1141 (48.20%), Query Frame = 3
Query: 273 LSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITE-------EWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDA-LSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKE---SELKIQENQMRKE---LIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEV----SQHKSTIERLTSEIKSRNNELQRLQD--RNEEKSNEMASKIKQIKDL---KSIAENLQQKFTEKERELKKALTEIKIMNEE-------SKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSH----EIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKK--DNNRL-MKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSK--YETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFND-------QIRDLQTQLSEKANITIDEHKEEVRSLQRKISLLEEQSKTVTNTHRLELERVASAKLKLDCNYQNLEKQLQNAINEN----AYLKKQIDDF--------------GNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP------NMGAXXXXXX--XXXXXXSFQKLTPLPGSPFHDDPINPAKPLP-PSSRKSF 3476
++QD+H KMSKKIAQLTKVIYALNTKND+NE+ L K QH +E + +L + +++ + K++ ++ +Q+ L+ I+ +E + +++ ++E+ R + + Q Q L Q + K +E+ ++ + E + +++ +++ + +E++++ EW N+ ++ + +I+ + E SH+ + ++ +D+ ++ + ++ L A + +T +FE E+ + +Q+E ++ QE ++RK+ L+ + +DL D L++E+ KL E+ S +ST+++L ++++ L +LQD RN S E + Q DL ++ L+ ++ ++++ + +I+ + +E K + C KS+TT+ V Q++ L++ E + E S++K H + L E + ++K+ LE+ K R K+ D++Q+ K++ ++K EE++K + ++ + +Q+K +L K K ++++ L + + + S + K+ T+K D R +K + + ++ E+D+L+L K+ + Q ++ L+AELD KWA+T+R E +LR ++ E++ A+E + + K+ E+ H + + +S+ ++ ++A E N+ Q +++ +L E+ K + + V +Q L++K + + LQ++ + + E E+A HL ++ + H+ + +E E + D + LQT+L E+ H+E +R +QR + +V RLEL+R + ++Q ++LQ I+++ LK ++ +D ++Q D E LR E ++K + + N H+ E + I FNKAQ + K+KI EL L+E +E++ R +R ED+E+I L + + E + +L EEKRF QLELVNRETNFNK+F++SPNVG+LNP GA + + + +L PLPGSP HD +NP KPLP P+ K F
Sbjct: 29 VTQDMHLKMSKKIAQLTKVIYALNTKNDENEVVLQIFKDQHEEEKKSLLADMETKIKHYRSKLEEESDHRRQMNILQTRISDFEQQQSSVEEQIAQLKEEAKAREQLLEGSYSRQMQQLTQDVLRAKREFEEHMEGFEAWKMQAEKKHMTELQEVEIKHAQELEQLRSFQRNQDTEWLNQ-----CAVIEEKYSDEIRQLKEKLEA-SHV-ERLKMEEDYVEKLAKAQAFYEQELKALQQSETSSFEGELNALR----------VQQEKLRNDFSAQERELRKQIDSLVRQLADAEDL--------ADALKQENE--KLTQEMKSKDSSAESTVQQLQQALQNKEAALVQLQDVERNLAASKERC--LDQAADLLKKSALIGELEAHRVQRAAQVEEMMKQIEHLKQELSRAEAEQKTLQLCQKSQTTEQVSQLEFLKQ-REVTKQRHEREIHSLKKASEEHLHQVQTSLQEKLAAIEKQ---HLEEKEKDR--------KAALDDLQQSKQDLEAKFWEEKTKLNDEKNSIQAEFEQVKAELLAKCKQAEEEVARLSSLVQESENGLGAASSHISSLKDAAATLKAELDKTRTELKNTKLHSASLQV---ELDKLQLLYN---------TKSAEWQLELKSLLESLAAELDAKWAETMRTECSKLRQEVTAQKDDERRAALEHLARLKDEEMVTDRAGLASHITYLKGQVSELNHKLDLAHSSREDDK----NNMQAALEVERARL---------EAELHKAQQDHKVAVQELEEKHQNSLLQTIQQKDAEREEGEKALKAIHLEDMQAQLSAHKLALVAAKEEAEQLLKARLKDVQEAHCLKQGQLQTELEER-------HEEILRKVQRDHA-------SVIQAARLELDRAVEISKQKTRDHQLQVQELQENISQHETHIVKLKDEVRKLQAGISSLNVIIVQKDHDAQQAQVDAKEHLRQVEEQLKKEQIRALDNQAADHKHEHEMMIVQFNKAQEILKDKISELQILLLEAEERYRQRDSRPEDLELIHQLRLEVQERELRVAQLIEEKRFYQLELVNRETNFNKVFSSSPNVGLLNPLQLKNKKKGAEGVPAKYLSAPSLGAPTRLDPLPGSPMHDSILNPTKPLPQPAFTKKF 1089
BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Match: V3ZZK5 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_231741 PE=4 SV=1) HSP 1 Score: 153.295 bits (386), Expect = 2.136e-35 Identity = 146/520 (28.08%), Postives = 261/520 (50.19%), Query Frame = 3
Query: 1989 LKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFED--HKSKTQ-NDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSL-IESHERAWADKHLIEINLLTNEHXXXXXXXXXXX-------XXXYVKQFNDQIRDLQTQLSEKANITIDE----HKEEVRS----LQRKISLLEEQSKTVTNTHRLE-LERVASAKLKLDCNYQNLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP------NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLPPSSRK 3470
L EID+LKL Q + + K K + L ELD KWA+TL+ ET +LR + E EK A+ + + ++ LT +E H Q DL + + + S+ +E+++ ++L +SE + KE+ + + Y I ++ + +EN+L+S+ E + L + E+ +KH+ ++ + H ++ ++ E +KQ ++ L+ +LSEK ++ H+ E+R+ L+R I + + K N R+E L+ + + + N + + L+ AI E LK+ I + + Q + ++++ E E + +++ + NL+ H ++ + + DFN AQ L K+KI + +L E ++++ R +R ED+E+I L + E ++ L +EKRF QLELVNRETNFNKIFN +PN+G++NP + ++ Q+L P+P SP HD +NP++PLPP ++K
Sbjct: 9 LAEIDKLKLQHASQLTEADVTSKG---------KLDALKTELDAKWAETLKNETNKLRKQIAEQLESEKHSAVLQLTLQHEKQVAELTSEWEGKVHALTIQITDLQRSANKNS--------------SKSSEELERLRLQMSELEKKLQKEMSEAEEDYARKI-SVMEAAQENQLKSLIERKDLELSEVEKKIKNKHVEDLQIQLTAHRAAVQNIQEQADKLRHDRETTLIKQHQQELDKLRLELSEKLEKDFEDVKRKHEAEIRAARIELERAIEI--SKQKDRDNHSRIEELQMEITKRERTIMNLEEETRNLKRAIEE---LKRDIKERDKQMKQVQNEAKKQIKQLEDEFRVEYERNVDNLQADHLQQINEMVGDFNTAQELLKDKISSIQIQLEEAEDRYRNRESRPEDLELIMQLRDAIQERELRVKELIDEKRFFQLELVNRETNFNKIFNTTPNIGVMNPLNPVKPKNKKNEKPLKHSSAPALSQRLDPIPNSPLHDGNLNPSRPLPPFNKK 499
BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Match: R7V5R4 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_107275 PE=4 SV=1) HSP 1 Score: 144.436 bits (363), Expect = 8.731e-35 Identity = 81/215 (37.67%), Postives = 126/215 (58.60%), Query Frame = 3
Query: 2841 DCNYQNLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP-----NMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLPPSSRK 3470
D +LE +LQN + ++++ G D R + + + RS E +++ F + +L +H+ E +Q +T+F +AQ + K+KI EL L E +++++ R +R ED+E+IQ L + +++I++L +EKR Q+ELVNRETNFNK+FN P VG++NP + A K +L PLPGSPFHD N AKPLPP S+K
Sbjct: 32 DQTISHLETELQNLQKGIDEMSRELEAKGKDVLRIRSEANAAARSLEDQVQKQFKSELNDLMDQHQNEAQQMLTEFTEAQEILKDKISELRILLEEAEDRYMNRESRAEDLEMIQNLQMAIREAQQQIQKLMDEKRHYQMELVNRETNFNKMFNGDPKVGVMNPLSYPTHKKAKGDKNGVRGSPSIHNRLDPLPGSPFHDGQFNTAKPLPPPSKK 246
BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Match: A0A2G8L3Z4 (FAM184 domain-containing protein (Fragment) OS=Stichopus japonicus OX=307972 GN=BSL78_08123 PE=4 SV=1) HSP 1 Score: 153.295 bits (386), Expect = 7.814e-34 Identity = 165/639 (25.82%), Postives = 294/639 (46.01%), Query Frame = 3
Query: 1764 LKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFNDQIRDLQTQLSEKANITID----EHKEEVRSLQRKISL--------LEEQSKTVTNTHRLELERVASAKLKLDCNYQNLEKQLQNAINEN-AYLKKQIDDFGN---DYSRSQQDFSEKLRSQE-SEIKHNFDQVILNLK---------------MKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAXXXXXXXXXXXXSFQ----------------------KLTPLPGSPFHDDPINPAKPL-------PPSSRKSFDNS*IFV 3497
+K +L++L+ DL K+K ++ L +I +D Q L ++ +KK+N++L ++ + E+ LK +LE KS + + + + ED +K + LS +LD KW++TLR+E +LR ++ E ++K A+E + KN EI+ +E ++ + ++S ++ ++ Q +++ +++ L+ H +E+ L+ S + + LK++ +E ++ ++ SL H + ADK +++ + ++ LQ + E +D EHK + L+ +++ L KT R+ELER + + D Q+ LQ + + ++ K DD D SRS+++ + ++QE +++ ++ I ++K +H ET+ + +FN+AQ+L K+KI L L E ++++ R +RDED+E+I +L ++ + +LN+EKRF QLEL+NRETNFNK+FN PNVGILNP K + S +L PLP SP HD +NP KPL P+ K F N I V
Sbjct: 429 IKRELEELQRDLTAKLKRAEEDAQKLSKILQERD-------QGLGSANSHIDGLKKNNSQLKTEIDLMQKELRERISEVHTLKTSLE--KSKHSHATEIAGLHEDGKKKIDHLSRDLDEKWSETLRKECDKLRQELTEQHREDKNAALEQINLLKNQEIEETRGGWEQRVTELRREISDLRGSLSSKSDKAKAELAQLQRQSEQELNKLKFDLATATENHQRELADLQKSLEREKEKLKEQQQEEMMKLESKLTSL---HNKTLADK---------------------------MEEHKEAVKSLQIESEESRRAELDIRLMEHKRSLDKLRLELTQRHSAEMDQLARAHKTQMAAARMELERAIELRQQQDRANQSRVDDLQGHVTQRETHISKLEDDIQKLKMDISRSKEEI--EFKAQEIMKVQGEAERRIRDVKEVLARSQKDELDSQSAEHLRETQGMLGEFNRAQDLLKDKISALQIMLEEAEDKYRNRESRDEDLEMIGSLKEMVAEKDQVLFKLNDEKRFFQLELINRETNFNKVFNTQPNVGILNPLAKPRKRGSSEAPRYVSAPNLNSSGMMVSASSSSAGSPSNPRLEPLPDSPIHDIQLNPKKPLREKNGAGKPTKGKRFINXMIDV 1026
BLAST of Family with sequence similarity 184 member A vs. Ensembl Cavefish
Match: fam184a (family with sequence similarity 184 member A [Source:NCBI gene;Acc:103041903]) HSP 1 Score: 122.094 bits (305), Expect = 1.466e-27 Identity = 184/800 (23.00%), Postives = 379/800 (47.38%), Query Frame = 3
Query: 276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQ--LIKDHERQMKEMNDLFDALSAESKEKTKNFEFEV---EEYKSRIFEYGKNSIQKESE----LKIQENQMRKELIEKSTFIKDLELKIQS------------------LEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELL-------ESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLM-KLSSDKDSDIE-TNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLK-------KKFEEN-KLQSVTETQSLIESH 2543
+QDLH KMSKKIAQLTKVIYALNTKND++E + TLK+ H +E+QQIL ET ++ + K+ ++ ++IQ L++++ +E + + +FE +++ + + ++ ++ +++ +++++ S+E+ L + + E EKR +E L+ + +E+Q + + QS Q+ Y+KDQ L + H+++++ +++ + L + K + +E ++ + + R E K + Q +E K E ++RKE + ++ K++S L+ E+NI L+ ++ + E + K EL+ +DR ++++ E+ K QI L++ + + E E + ++ + EE + N S++ QI +L++ ++ + K+++E ELL E K LE+ +KK + S + E +L E + + ++ERS + +L+ LD L+ +L+ K+ + ++ L+EI +K Q L K ++ ++K+ +L+ +L + + E TNL + L+ +E QK +E K + +E+ K +K++ EL++KW +TLR+E +LR ++ E + K+ A+ + + K E+ +++ +S + + + + +Q +++ + + L E ++ H + E+L+ ++ IQ+++ K+ EE + Q E QS+ E+H
Sbjct: 42 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALAEFESYRQRVEDMQLCTEAQHTQRVVTMSREVEEMRRSFEEKLRSFGQVQAQFEQEKRQALEELRTSHRQEVQEML-----RSHQS----------------------QNANYSKDQEKLGQLHKQEVEALSERVEELKQDKKRLVEEYEAKLNKAQAFYERELEAMKRTQQMTAENLLAWKKTEAELRKEFQAQEAALQKTLGKLRSELQRVQDESRESREKSHKLQASLTASENNIKDLHKQLDEVTQDAEIIAIRQKEAEVELEATRDRVQQQATEILLKASQIGSLQATQMTHEAAIRDLESEKSRLKDKVVRLEEERGALQNKSQALDERQRQQILSLEK--------------TLREEKQAYEKELLNLRSKYEEDTAHFKDAQSRALEELSKKHRAALENTQSSSEKEKNRLLAEMEQQFEKERSALEEQKRRLREQLDSLREELSAKLSMANSEVSRLQEI-------VKEGEQGLGSAKGHISSLKEAQEKLLEELDATRARLRETTNL--LTALQGEMETQKQQHEA--KLITTKEEEKLKMDKMALELELKWTETLRQECKKLREELREDHEEGKRMALTQLAQSKEQELGTARESWQRKVEDLLEQISLLKQSLEMQLSQSQRSLQQLQAQFSQEREHLGQQLQELEMEHQRREERLREAHCCAIQDMQEARQHDLKELEERLRQQHHMELQSMREAH 789
BLAST of Family with sequence similarity 184 member A vs. Ensembl Cavefish
Match: fam184a (family with sequence similarity 184 member A [Source:NCBI gene;Acc:103041903]) HSP 1 Score: 121.709 bits (304), Expect = 1.961e-27 Identity = 166/692 (23.99%), Postives = 333/692 (48.12%), Query Frame = 3
Query: 276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQ--LIKDHERQMKEMNDLFDALSAESKEKTKNFEFEV---EEYKSRIFEYGKNSIQKESE----LKIQENQMRKELIEKSTFIKDLELKIQS------------------LEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELL-------ESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLM-KLSSDKDSDIE-TNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEID 2243
+QDLH KMSKKIAQLTKVIYALNTKND++E + TLK+ H +E+QQIL ET ++ + K+ ++ ++IQ L++++ +E + + +FE +++ + + ++ ++ +++ +++++ S+E+ L + + E EKR +E L+ + +E+Q + + QS Q+ Y+KDQ L + H+++++ +++ + L + K + +E ++ + + R E K + Q +E K E ++RKE + ++ K++S L+ E+NI L+ ++ + E + K EL+ +DR ++++ E+ K QI L++ + + E E + ++ + EE + N S++ QI +L++ ++ + K+++E ELL E K LE+ +KK + S + E +L E + + ++ERS + +L+ LD L+ +L+ K+ + ++ L+EI +K Q L K ++ ++K+ +L+ +L + + E TNL + L+ +E QK +E K + +E+ K +K++ EL++KW +TLR+E +LR ++ E + K+ A+ + + K E+
Sbjct: 42 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALAEFESYRQRVEDMQLCTEAQHTQRVVTMSREVEEMRRSFEEKLRSFGQVQAQFEQEKRQALEELRTSHRQEVQEML-----RSHQS----------------------QNANYSKDQEKLGQLHKQEVEALSERVEELKQDKKRLVEEYEAKLNKAQAFYERELEAMKRTQQMTAENLLAWKKTEAELRKEFQAQEAALQKTLGKLRSELQRVQDESRESREKSHKLQASLTASENNIKDLHKQLDEVTQDAEIIAIRQKEAEVELEATRDRVQQQATEILLKASQIGSLQATQMTHEAAIRDLESEKSRLKDKVVRLEEERGALQNKSQALDERQRQQILSLEK--------------TLREEKQAYEKELLNLRSKYEEDTAHFKDAQSRALEELSKKHRAALENTQSSSEKEKNRLLAEMEQQFEKERSALEEQKRRLREQLDSLREELSAKLSMANSEVSRLQEI-------VKEGEQGLGSAKGHISSLKEAQEKLLEELDATRARLRETTNL--LTALQGEMETQKQQHEA--KLITTKEEEKLKMDKMALELELKWTETLRQECKKLREELREDHEEGKRMALTQLAQSKEQELG 681
BLAST of Family with sequence similarity 184 member A vs. Ensembl Cavefish
Match: fam184a (family with sequence similarity 184 member A [Source:NCBI gene;Acc:103041903]) HSP 1 Score: 102.449 bits (254), Expect = 1.630e-21 Identity = 55/165 (33.33%), Postives = 105/165 (63.64%), Query Frame = 3
Query: 276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRI 770
+QDLH KMSKKIAQLTKVIYALNTKND++E + TLK+ H +E+QQIL ET ++ + K+ ++ ++IQ L++++ +E + + +FE +++ + + ++ ++ +++ +++++ S+E+ L + + E EKR +E L+ + +E+Q +
Sbjct: 42 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALAEFESYRQRVEDMQLCTEAQHTQRVVTMSREVEEMRRSFEEKLRSFGQVQAQFEQEKRQALEELRTSHRQEVQEM 206
BLAST of Family with sequence similarity 184 member A vs. Ensembl Cavefish
Match: zgc:85722 (zgc:85722 [Source:ZFIN;Acc:ZDB-GENE-040516-7]) HSP 1 Score: 94.7449 bits (234), Expect = 3.440e-19 Identity = 57/196 (29.08%), Postives = 118/196 (60.20%), Query Frame = 3
Query: 276 SQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQA 863
+QDLH KMSKKIAQLTKVIYALNTKND++E + +LK+ H E+Q IL ET +++ + KM +++Q L++++ +E + + +F+++++ + + ++ ++ +++ +++++ +E+ L + + E EK +E+LK+ + +E+Q + E ++ QS + + +K ++ A+ +A
Sbjct: 4 TQDLHLKMSKKIAQLTKVIYALNTKNDEHEEAIQSLKEAHEDEVQHILSETRDKILQYKSKMGDEAELKRRLQSLEESVELHEHMKRQALAEFQMYRQRMEDSQLCAEAQHTQRVVSMSREVEEMRHDFEEKLRSFSQVQAQFEQEKLRNMEDLKLAHRQELQELLE---TQQSQSASSCLDQEKLAELHRAELEA 196
BLAST of Family with sequence similarity 184 member A vs. Ensembl Sea Lamprey
Match: fam184a (family with sequence similarity 184 member A [Source:ZFIN;Acc:ZDB-GENE-041014-214]) HSP 1 Score: 64.3142 bits (155), Expect = 1.403e-10 Identity = 33/127 (25.98%), Postives = 74/127 (58.27%), Query Frame = 3
Query: 324 KVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNM 704
+VIYALNTKND++E ++ L++ H++E+QQ ET +R+ Q ++ + ++ + L++ +AS L + +++ E +++ ER +D ++ ++ L+ + D+K +E + + +L +
Sbjct: 1 QVIYALNTKNDEHEAAVSVLREAHAEEMQQFAAETRHRLLRYQSRLGVESELREKARSLEEALASEGSLRRQAQEQLEAYRRHVEERDAGRDAEHADRILALSTQMLDMKRDFEAKILGFTSLQKRL 127
BLAST of Family with sequence similarity 184 member A vs. Ensembl Medaka
Match: fam184a (family with sequence similarity 184 member A [Source:NCBI gene;Acc:101175129]) HSP 1 Score: 112.079 bits (279), Expect = 1.575e-24 Identity = 60/159 (37.74%), Postives = 103/159 (64.78%), Query Frame = 3
Query: 2859 LEKQLQNAINEN-AYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNP 3332
L++Q+ + +NEN + L K+++ G + + + + ++++R+ E E+ ++ + + H ET+ ++DFNKAQ + K+KI L L +E+F R +R ED+++I L E +++L ++K+F QLELVNRETNFNK+FNASPNVG++NP
Sbjct: 841 LDRQI-HTLNENISSLTKELETKGKEVLKIRSEANQQIRAHEQELMKRHERELSEMNAAHSRETQNMLSDFNKAQEVLKDKISALQILLEGTEEKFRNRESRPEDLQVIAELKDMVSERETLVKKLVDDKKFYQLELVNRETNFNKVFNASPNVGVINP 998
BLAST of Family with sequence similarity 184 member A vs. Ensembl Medaka
Match: zgc:85722 (protein FAM184A [Source:NCBI gene;Acc:105357787]) HSP 1 Score: 90.5077 bits (223), Expect = 7.622e-18 Identity = 50/189 (26.46%), Postives = 110/189 (58.20%), Query Frame = 3
Query: 219 KPHKNTLNGFKYTMDQDS-----LSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRI 770
+P ++ + K+ S ++DLH KMSKKIAQLTKVIYALNTKND++E + +LK+ H E+Q I+ ET +++ + KM + +++ L++++ +E + + +FE++++ + + ++ ++ +++ +++++ +E+ L + E+EKR +++L+ + E++ +
Sbjct: 8 QPSFSSASAAKFIAPPPSGLTLEYTRDLHLKMSKKIAQLTKVIYALNTKNDEHEEEIESLKEAHEDEVQHIVTETRDKIMQYKTKMADEADLRRRLASLEESVELHEHMKRQALAEFEMYRQRMEDSQLCTEAQHTQRVVSMSREVEEMRRDFEEKLRAFSQAQAQFEAEKRRALDDLRATHRHEVEEL 196
BLAST of Family with sequence similarity 184 member A vs. Ensembl Medaka
Match: zgc:85722 (protein FAM184A [Source:NCBI gene;Acc:105357787]) HSP 1 Score: 90.5077 bits (223), Expect = 7.779e-18 Identity = 50/189 (26.46%), Postives = 110/189 (58.20%), Query Frame = 3
Query: 219 KPHKNTLNGFKYTMDQDS-----LSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRI 770
+P ++ + K+ S ++DLH KMSKKIAQLTKVIYALNTKND++E + +LK+ H E+Q I+ ET +++ + KM + +++ L++++ +E + + +FE++++ + + ++ ++ +++ +++++ +E+ L + E+EKR +++L+ + E++ +
Sbjct: 8 QPSFSSASAAKFIAPPPSGLTLEYTRDLHLKMSKKIAQLTKVIYALNTKNDEHEEEIESLKEAHEDEVQHIVTETRDKIMQYKTKMADEADLRRRLASLEESVELHEHMKRQALAEFEMYRQRMEDSQLCTEAQHTQRVVSMSREVEEMRRDFEEKLRAFSQAQAQFEAEKRRALDDLRATHRHEVEEL 196
BLAST of Family with sequence similarity 184 member A vs. Ensembl Medaka
Match: fam184b (trichohyalin [Source:NCBI gene;Acc:101174322]) HSP 1 Score: 65.0846 bits (157), Expect = 4.813e-10 Identity = 38/114 (33.33%), Postives = 62/114 (54.39%), Query Frame = 3
Query: 231 NTLNGFKYTM---DQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELF 563
+T+NG + +Q+ +H KM KKIAQLTKVIY+LN +N+++E L L H E+ +IL ET + EG + +L EL++++ + + + + FE F
Sbjct: 22 STVNGTAAELPNIEQELYDYQMHSKMCKKIAQLTKVIYSLNMRNEEHETALQALSHAHHDELHRILVETCHEGEGSALRTRLL--------ELQESLDEQQRVGAQVQADFEFF 127
BLAST of Family with sequence similarity 184 member A vs. Planmine SMEST
Match: SMESG000058677.1 (SMESG000058677.1) HSP 1 Score: 2041.54 bits (5288), Expect = 0.000e+0 Identity = 1093/1103 (99.09%), Postives = 1097/1103 (99.46%), Query Frame = 3
Query: 177 MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFNDQIRDLQTQLSEKANITIDEHKEEVRSLQRKISLLEEQSKTVTNTHRLELERVASAKLKLDCNYQNLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS 3485
MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDET+NRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKE+NDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSK+DEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLV MKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLN SQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEV+SLQRKISLLEEQSK VTNTHRLELERVASAKLKLDCNYQ LEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIK NFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFV RPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAIKTKKINNDKIKSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS
Sbjct: 1 MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETNNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKELNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKMDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVIMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLNVSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEVKSLQRKISLLEEQSKAVTNTHRLELERVASAKLKLDCNYQKLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKRNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVNRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAIKTKKINNDKIKSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS 1103
BLAST of Family with sequence similarity 184 member A vs. Planmine SMEST
Match: SMESG000058677.1 (SMESG000058677.1) HSP 1 Score: 1982.22 bits (5134), Expect = 0.000e+0 Identity = 1066/1076 (99.07%), Postives = 1070/1076 (99.44%), Query Frame = 3
Query: 258 MDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFNDQIRDLQTQLSEKANITIDEHKEEVRSLQRKISLLEEQSKTVTNTHRLELERVASAKLKLDCNYQNLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAXXXXXXXXXXXXSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS 3485
MDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDET+NRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKE+NDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSK+DEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLV MKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLN SQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEV+SLQRKISLLEEQSK VTNTHRLELERVASAKLKLDCNYQ LEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIK NFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFV RPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAIKTKKINNDKIKSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS
Sbjct: 1 MDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETNNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKELNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKMDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVIMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLNVSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEVKSLQRKISLLEEQSKAVTNTHRLELERVASAKLKLDCNYQKLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKRNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVNRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGAIKTKKINNDKIKSFQKLTPLPGSPFHDDPINPAKPLPPSSRKSFDNS 1076
BLAST of Family with sequence similarity 184 member A vs. Planmine SMEST
Match: SMESG000058677.1 (SMESG000058677.1) HSP 1 Score: 1957.96 bits (5071), Expect = 0.000e+0 Identity = 1046/1056 (99.05%), Postives = 1050/1056 (99.43%), Query Frame = 3
Query: 177 MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETSNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKEMNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRAXXXXXXXXXXXXSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKLDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVTMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAXXXXXXXXXXXXNDSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHXXXXXXXXXXXXXXYVKQFNDQIRDLQTQLSEKANITIDEHKEEVRSLQRKISLLEEQSKTVTNTHRLELERVASAKLKLDCNYQNLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKHNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVTRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGA 3344
MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDET+NRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKE+NDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSK+DEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLV MKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLN SQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEV+SLQRKISLLEEQSK VTNTHRLELERVASAKLKLDCNYQ LEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIK NFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFV RPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGA
Sbjct: 1 MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKVIYALNTKNDDNEMTLNTLKQQHSKEIQQILDETNNRVEGLQKKMKLTINNTQQIQELKQTIASYEDLLTETKQKFELFQKESNERTKEKDLKNVEQTQMLNQTIKDLKSSYEQLLDDYYTLNTNMESEKRLKIENLKVDYEKEIQRITEEWKNKEKQSKALIVGSQKEIQIQLADAQAEIQSHIYAKDQLIKDHERQMKELNDLFDALSAESKEKTKNFEFEVEEYKSRIFEYGKNSIQKESELKIQENQMRKELIEKSTFIKDLELKIQSLEKDCLEKESNISKLNIEVSQHKSTIERLTSEIKSRNNELQRLQDRNEEKSNEMASKIKQIKDLKSIAENLQQKFTEKERELKKALTEIKIMNEESKEMANCSKSETTDYVIQIQTLQRALEELNKERLEEKSSMEKLKRSHEIELLESVGRMKKECESDLEKSNKKREKEFVLKEKSFQDEIQKLKEEFQSKMDEERSKASKIIEKLKFDLDQLKNDLNIKVKGKDKQIINLEEITIGKDKEIKTLSQQLKENKENLVIMKKDNNRLMKLSSDKDSDIETNLKEIDRLKLNLEEQKSLNENIRKNVQIQEDMSEKYNKLSAELDMKWADTLRRETGRLRNDMLESFAKEKQKAIEMVEKKKNNEIDLLTFNFEDHKSKTQNDLSKYETEVAKLKEEIIHLKKLNVSQITEKIQEVQLLLSETQIIHAKEIEKLKNSYDVNIQNLKKKFEENKLQSVTETQSLIESHERAWADKHLIEINLLTNEHEKKMKMKLDEMENKYVKQFNDQIRDLQTQLSEKANITIDEHKEEVKSLQRKISLLEEQSKAVTNTHRLELERVASAKLKLDCNYQKLEKQLQNAINENAYLKKQIDDFGNDYSRSQQDFSEKLRSQESEIKRNFDQVILNLKMKHEEETKQTITDFNKAQNLYKEKIKELNSRLMEIDEQFVNRPARDEDIEIIQTLTAQTKLYEKEIERLNEEKRFLQLELVNRETNFNKIFNASPNVGILNPNMGA 1056 The following BLAST results are available for this feature:
BLAST of Family with sequence similarity 184 member A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Family with sequence similarity 184 member A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Family with sequence similarity 184 member A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Family with sequence similarity 184 member A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Family with sequence similarity 184 member A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Family with sequence similarity 184 member A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Family with sequence similarity 184 member A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Family with sequence similarity 184 member A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Family with sequence similarity 184 member A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 4
BLAST of Family with sequence similarity 184 member A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Family with sequence similarity 184 member A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Family with sequence similarity 184 member A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Family with sequence similarity 184 member A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 4
BLAST of Family with sequence similarity 184 member A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30004447 ID=SMED30004447|Name=Family with sequence similarity 184 member A|organism=Schmidtea mediterranea sexual|type=transcript|length=3498bpback to top protein sequence of SMED30004447-orf-1 >SMED30004447-orf-1 ID=SMED30004447-orf-1|Name=SMED30004447-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1104bp MTSTTSDYFLNNNQKPHKNTLNGFKYTMDQDSLSQDLHFKMSKKIAQLTKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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