G_PROTEIN_RECEP_F1_2 domain-containing protein

Overview
NameG_PROTEIN_RECEP_F1_2 domain-containing protein
Smed IDSMED30004445
Length (bp)933
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30004445) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30004445) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30004445

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30004445SMESG000079790.1 SmedASXL_003798SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
non-ciliated neuronSMED30004445SMESG000079790.1 dd_Smed_v4_78717_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30004445SMESG000079790.1 dd_Smed_v6_80306_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30004445SMESG000079790.1 dd_Smed_v6_88303_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: SSTR1 (somatostatin receptor 1 [Source:HGNC Symbol;Acc:HGNC:11330])

HSP 1 Score: 52.373 bits (124), Expect = 5.384e-7
Identity = 48/203 (23.65%), Postives = 92/203 (45.32%), Query Frame = 3 
Query:  252 SIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITY-----YIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALK 845
            SI+C+ ++++DR+VAVV P+K   ++      ++ +    L+LL   P    F+R+A N   + AC    N  + E   R  V  + Y     +++P   + LC V +I KM ++A        K +    TL  M + +  +   +    + +  + + + D  V  +S+      IL Y++   N IL+      F+ + +
Sbjct:  144 SIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIV-VFSRTAANSDGTVAC----NMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSV------ILGYANSCANPILYGFLSDNFKRSFQ 335
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-6 (FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q8I7K6])

HSP 1 Score: 55.4546 bits (132), Expect = 1.429e-8
Identity = 76/314 (24.20%), Postives = 144/314 (45.86%), Query Frame = 3 
Query:    3 LIIVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRF-------VLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFT---RSAVNDSDSGACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTL--TRMSXXXXXXXXXXXXXXXVMWTILSLRADI---NVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNKITSNSMDGLS 899
            L I+  G   N L++ V+T+   R ++ +  +  LS+ D  V+L   +P    +  P+  ++    S+  +   F       +   A   S++ +++IT++R++AV  P+++  W + KN + IVI     +++ N P F+ +      A+        L     + Y   Y   +S+I  Y++P ++M + N+ VI   N L K++   A   T   K    T M + +TIL+      ++ +    S+  D    + E   ++  VS+IL+  H    F ++     RFR  L  LFK  + +  NS+  L+
Sbjct:   15 LPIILVGLVGNGLSLYVYTTPNMRKSTVAFLLYSLSICDIFVLLFA-LPLYSISYLPIWDNVYGAWSMRRMFIAFSTKFFYPLCMTAKTASLYIMVVITVERWIAVCRPLQVHIWCTFKNSVRIVIAIITFSIILNFPKFFEYQIGYSDALGYWPKRGILDAEEHWWYYISYFIIISVIFDYLLPFVIMFIANMKVI---NELRKSRKERALLTTSLQKEQNTTVMLLVVTILFGFCHFFSMALKLFESIFKDFLNRHNEYFEVMIEVSNILIVIHIGTTFFIYYFFSARFRNILCYLFKKRSNLPDNSLTDLN 324
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-8 (FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q20686])

HSP 1 Score: 54.6842 bits (130), Expect = 3.707e-8
Identity = 74/297 (24.92%), Postives = 130/297 (43.77%), Query Frame = 3 
Query:    9 IVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSAL--NPLNPDLISISSVSCVLHRF---------VLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSG---ACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAK-NQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLF 854
            I   G  A  + ++VFT K  RS S + ++  LS+ D  ++L+      FSAL  +PL   ++     + V H F         +   A   S+W  + +T+DRF+AV  P+  K W + +    I+I     ++L   P F+  T    ND D G      +  N + Y+  Y  +  LI   +IP  VMI+ NVFV+  ++   K  +++   K     K   R    + I  +       V+  + +L   +    +     + ++L+  + + N +++ L G RFR    L+ 
Sbjct:   54 ICVLGAGAAVMCIVVFTRKQMRS-SLNVYLAGLSVFD-LILLS------FSALIFSPLQGCVLQGHGDTAVCHFFWRSTPWTLPISNIAQCGSVWTCVAVTVDRFLAVNYPLHSKIWCTPRRATTILIAITVFSILFKAPMFFELT----ND-DCGRLRTSFLRDNKY-YKEYYVTFGYLIALLLIPWTVMIILNVFVVKAVHKAYKIRRSMQGGKNNQEEK--DRRCTLMAIAMVLTFLIFNVVAAVNNLAETVFEVSLGFWSPIGNLLICLNSASNIVIYSLFGARFRQMCVLML 334
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-11 (FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q9GYH2])

HSP 1 Score: 53.1434 bits (126), Expect = 9.527e-8
Identity = 63/313 (20.13%), Postives = 145/313 (46.33%), Query Frame = 3 
Query:    3 LIIVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVS------CVLHRFVLFAAGDL-SIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDS-GACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVE--IMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNKITSNSMDGLSIANK 911
            L ++  G   N +++ V++      N+    +  LS  D  V++T  +P+  +   P  P    I SV       C+++ + L   G +   + ++LI+++R+ AV  P++++ W ++KN +  +     +++L N P F+ F  + +      G   I+ N + Y   Y    ++I   +IP  ++ + N+ VI ++    + + +  +++   +KT T + + I +  I       V +  L     +  +  I  II+ +S++L+  + +  F ++++   ++R  L     C N       D L+++++
Sbjct:   42 LPLILIGIFGNIISIYVYSRHHMNKNTIGFLLLSLSTIDLIVLITA-MPSFGTYKFPFFPGYHEIGSVHTIFSAFCLIYFYPLMCMGKMMGQYIIVLISVERWFAVCRPLQVQIWCTQKNTIRAMTCIIAISILFNAPRFFEFKANLITGVIGFGLAHISKNEW-YFYLYYGIRAIIFDALIPFSIIAVTNIQVIQQLRKSNEERKLMTTQQQKDNKTTTMLLVMIFMYAICHFLCTSVKFINLFSHNYVQFQFVIFKIIHHISNVLLVFYSASTFFIYLIFSEKYRNVLSTCVTCRNT------DELTVSSR 346
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-10 (FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:O45096])

HSP 1 Score: 50.8322 bits (120), Expect = 4.148e-7
Identity = 52/213 (24.41%), Postives = 98/213 (46.01%), Query Frame = 3 
Query:  240 AGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADIN--VEIMS--IIY----SVSDILVYSHHSCNFILFVLTGGRF-RTALKLL 851
            A   S+W  + +T+DRF+AV  P+K + W ++ N + ++    F++ +   P+F+   R   N       L  + F+I    +  +V+ I   +IP  ++I  N  +I K+ +  + Q        H S  L             + T   +++ I ++   IN  V+  S   +Y     +S++LV  + + N +++ +   RF R ALKLL
Sbjct:   41 AQAGSVWTYVAVTVDRFIAVCFPIKRRVWSTRSNTITVLFVITFISAIFKLPSFFE-VRLDHNGEVEPTELRKNEFYIEFYLFYLYVTFIQ--LIPWTLIIFLNAIIIHKVRLAYRAQ----EAMVHNSGKLNTKREDAERKVTVMATVMTMIFIICNIPPGINYLVDRYSNPTVYRQRIPLSNVLVCVNSASNMMIYCVFNSRFRRAALKLL 246
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: AstA-R2 (gene:FBgn0039595 transcript:FBtr0085316)

HSP 1 Score: 47.3654 bits (111), Expect = 8.565e-6
Identity = 56/221 (25.34%), Postives = 105/221 (47.51%), Query Frame = 3 
Query:  252 SIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDS------GACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYS-KTLTRMSXXXXXXXXXXXXXXXVMWTILSLRA-DINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNKITSNSMD 890
            SI+ ++L++IDRF+AVV P++ +  ++ +N+ LI I   ++ +L        FT   V D D+      G C   +N F+    Y+     I+ Y++P  +MI+  +++   M +  +   V  SKE+    K +TR+ + + I + +L  P  ++  + SL   + N     +I   +  L YS    N +L+      FR A      C ++  + + D
Sbjct:  125 SIYTLVLMSIDRFLAVVHPIRSRMMRT-ENITLIAIVTLWIVVLVVSVPV-AFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQV-TFFISSYLLP--LMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNCSSRYQNYTSD 340
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: AstA-R2 (gene:FBgn0039595 transcript:FBtr0336790)

HSP 1 Score: 47.3654 bits (111), Expect = 8.565e-6
Identity = 56/221 (25.34%), Postives = 105/221 (47.51%), Query Frame = 3 
Query:  252 SIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDS------GACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYS-KTLTRMSXXXXXXXXXXXXXXXVMWTILSLRA-DINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNKITSNSMD 890
            SI+ ++L++IDRF+AVV P++ +  ++ +N+ LI I   ++ +L        FT   V D D+      G C   +N F+    Y+     I+ Y++P  +MI+  +++   M +  +   V  SKE+    K +TR+ + + I + +L  P  ++  + SL   + N     +I   +  L YS    N +L+      FR A      C ++  + + D
Sbjct:  125 SIYTLVLMSIDRFLAVVHPIRSRMMRT-ENITLIAIVTLWIVVLVVSVPV-AFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQV-TFFISSYLLP--LMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNCSSRYQNYTSD 340
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: CNMaR (gene:FBgn0053696 transcript:FBtr0091684)

HSP 1 Score: 47.3654 bits (111), Expect = 9.360e-6
Identity = 48/200 (24.00%), Postives = 92/200 (46.00%), Query Frame = 3 
Query:   21 GTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSA-LNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITYYIIPTIVMIL--CNVFVIWKMNILAKNQTVNASK 611
            G+  N L+V VF     R  S+S ++  L++SD T  L G    +F+  LN LN D+ +  +  C    F  + A   S+W V+  T++RF+AV+ P+K +   + +   +++     +  L   P         +   ++  C +NS +      +  W +++ Y +  T + +L  C    +WK   + +  T++  K
Sbjct:   73 GSIGNILSVFVFFRTKLRKLSSSFYLAALAVSD-TCFLAG----LFAQWLNFLNVDIYN-QNYFCQFFTFFSYLASFCSVWFVVAFTVERFIAVIYPLKRQTMCTVRRAKIVLFCLTLVGCLHCLPYIVIAKPVFMPKLNTTICDLNSEYKEQLALFNYWDTIVVYAVPFTTIAVLNTCTGCTVWKFATVRRTLTMHKMK 266
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Sstr1 (somatostatin receptor 1 [Source:MGI Symbol;Acc:MGI:98327])

HSP 1 Score: 52.373 bits (124), Expect = 3.533e-7
Identity = 48/203 (23.65%), Postives = 92/203 (45.32%), Query Frame = 3 
Query:  252 SIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITY-----YIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALK 845
            SI+C+ ++++DR+VAVV P+K   ++      ++ +    L+LL   P    F+R+A N   + AC    N  + E   R  V  + Y     +++P   + LC V +I KM ++A        K +    TL  M + +  +   +    + +  + + + D  V  +S+      IL Y++   N IL+      F+ + +
Sbjct:  144 SIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIV-VFSRTAANSDGTVAC----NMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSV------ILGYANSCANPILYGFLSDNFKRSFQ 335
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Sstr1 (somatostatin receptor 1 [Source:MGI Symbol;Acc:MGI:98327])

HSP 1 Score: 52.373 bits (124), Expect = 3.533e-7
Identity = 48/203 (23.65%), Postives = 92/203 (45.32%), Query Frame = 3 
Query:  252 SIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITY-----YIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALK 845
            SI+C+ ++++DR+VAVV P+K   ++      ++ +    L+LL   P    F+R+A N   + AC    N  + E   R  V  + Y     +++P   + LC V +I KM ++A        K +    TL  M + +  +   +    + +  + + + D  V  +S+      IL Y++   N IL+      F+ + +
Sbjct:  144 SIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIV-VFSRTAANSDGTVAC----NMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSV------ILGYANSCANPILYGFLSDNFKRSFQ 335
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|P28646|SSR1_RAT (Somatostatin receptor type 1 OS=Rattus norvegicus OX=10116 GN=Sstr1 PE=2 SV=1)

HSP 1 Score: 52.373 bits (124), Expect = 2.449e-6
Identity = 48/203 (23.65%), Postives = 92/203 (45.32%), Query Frame = 3 
Query:  252 SIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITY-----YIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALK 845
            SI+C+ ++++DR+VAVV P+K   ++      ++ +    L+LL   P    F+R+A N   + AC    N  + E   R  V  + Y     +++P   + LC V +I KM ++A        K +    TL  M + +  +   +    + +  + + + D  V  +S+      IL Y++   N IL+      F+ + +
Sbjct:  144 SIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIV-VFSRTAANSDGTVAC----NMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSV------ILGYANSCANPILYGFLSDNFKRSFQ 335
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|P30873|SSR1_MOUSE (Somatostatin receptor type 1 OS=Mus musculus OX=10090 GN=Sstr1 PE=1 SV=1)

HSP 1 Score: 52.373 bits (124), Expect = 2.471e-6
Identity = 48/203 (23.65%), Postives = 92/203 (45.32%), Query Frame = 3 
Query:  252 SIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITY-----YIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALK 845
            SI+C+ ++++DR+VAVV P+K   ++      ++ +    L+LL   P    F+R+A N   + AC    N  + E   R  V  + Y     +++P   + LC V +I KM ++A        K +    TL  M + +  +   +    + +  + + + D  V  +S+      IL Y++   N IL+      F+ + +
Sbjct:  144 SIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIV-VFSRTAANSDGTVAC----NMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSV------ILGYANSCANPILYGFLSDNFKRSFQ 335
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|P30872|SSR1_HUMAN (Somatostatin receptor type 1 OS=Homo sapiens OX=9606 GN=SSTR1 PE=1 SV=1)

HSP 1 Score: 52.373 bits (124), Expect = 2.585e-6
Identity = 48/203 (23.65%), Postives = 92/203 (45.32%), Query Frame = 3 
Query:  252 SIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITY-----YIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALK 845
            SI+C+ ++++DR+VAVV P+K   ++      ++ +    L+LL   P    F+R+A N   + AC    N  + E   R  V  + Y     +++P   + LC V +I KM ++A        K +    TL  M + +  +   +    + +  + + + D  V  +S+      IL Y++   N IL+      F+ + +
Sbjct:  144 SIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIV-VFSRTAANSDGTVAC----NMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSV------ILGYANSCANPILYGFLSDNFKRSFQ 335
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q49LX5|SSR1_CANLF (Somatostatin receptor type 1 OS=Canis lupus familiaris OX=9615 GN=SSTR1 PE=3 SV=1)

HSP 1 Score: 52.373 bits (124), Expect = 2.609e-6
Identity = 48/203 (23.65%), Postives = 92/203 (45.32%), Query Frame = 3 
Query:  252 SIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITY-----YIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALK 845
            SI+C+ ++++DR+VAVV P+K   ++      ++ +    L+LL   P    F+R+A N   + AC    N  + E   R  V  + Y     +++P   + LC V +I KM ++A        K +    TL  M + +  +   +    + +  + + + D  V  +S+      IL Y++   N IL+      F+ + +
Sbjct:  143 SIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIV-VFSRTAANSDGTVAC----NMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSV------ILGYANSCANPILYGFLSDNFKRSFQ 334
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A1S3JYU6 (C5a anaphylatoxin chemotactic receptor 1 OS=Lingula unguis OX=7574 GN=LOC106177380 PE=3 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 3.994e-30
Identity = 89/316 (28.16%), Postives = 163/316 (51.58%), Query Frame = 3 
Query:    6 IIVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALL-KNCPTFWTFTRSAVNDSDSGACLI-NSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVN---ASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLR-------ADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNK-ITSNSMDGLSIANKL 914
            +++  G + N L++LV   K  R +SAS ++ YL+++D + ++ G  P    AL  +  D+ ++   +C LH + L++AGD ++W ++ +T+DRF++V  P K K W +K+  L+  +   F+ALL KN    WT  R    D+    C +    F  +ET  R+W+  I Y  IP + +I+ N  + + ++  A++Q  N   +S     ++T    S    +L ++L    +V  +I  L           +  +  ++ +++D LVY++HS NF L+ LTG  FR    LL    ++ +     +G S  N++
Sbjct:   39 MLLVIGITGNVLSLLVMRGKSLRPSSASIYLRYLAIADTSTLVLGVFPVWIRALTTV--DVTALHPWTCKLHVYFLYSAGDCAVWVIVAVTVDRFLSVTFPFKAKLWCTKRRALISCVVITFVALLVKNSHLLWT--RGFQYDATGAVCGVARKEFAFFETVIRSWIGFILYAFIPILSIIILNSLIAFGLH-KAQHQRQNLFGSSSSQAVTETANFRSSTYMLLALSLAFVVLVTPSITVLLLSPYWVVTPHDRALEELLQAITDSLVYTNHSINFFLYCLTGKGFRREFFLLIGIKSRQVMPEPREGGSDPNRV 349
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A0K0PVM1 (Orphan G-protein coupled receptor 1 OS=Platynereis dumerilii OX=6359 PE=2 SV=1)

HSP 1 Score: 111.694 bits (278), Expect = 2.340e-24
Identity = 86/306 (28.10%), Postives = 158/306 (51.63%), Query Frame = 3 
Query:    6 IIVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFI-----YETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVNASKE-THYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNKITSNSMDGLSIA 905
            +I   G   N L V+V +    R N+ + ++  L+++DA  + +G IP    A N +      +S  +C   + + + + D +IW ++  T DRF+AV  P +   W + +  ++I       A +KN   FW  TR A  D ++G  + N  +       +E   R W+  +   +IP +V++ CN+ +++K+  LA  +  + SK  + YS+T T M + ++ L++   TP++VM+   S     + +   +  +V+++LVY +HS NF ++ ++G RFR    L+F C  ++T  S  GLS A
Sbjct:   47 LIFIIGMVGNVLIVIVMSRNKMRGNTTAIYLPVLAIADAFALFSGIIPEWMEACNIIK--FKELSPGTCRFEKIIFYTSADTAIWILVAFTCDRFIAVCFPFRKSRWCTSRKAIIISASLLVAAFIKNMHVFW--TRGAQYD-ENGTFIKNCGYPRPEYKNFERNVRPWLVFVLVNLIPFLVILSCNLAIVYKL--LAATRIKDISKPNSKYSQT-TLMCVGVSFLFLLTTTPSVVMYIGRSEWDKSHTDAYEVAKAVTNVLVYLNHSLNFFVYCMSGKRFRREF-LMFCCCGRVT-ESGSGLSSA 342
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A1S3K5D9 (growth hormone secretagogue receptor type 1-like OS=Lingula unguis OX=7574 GN=LOC106178908 PE=3 SV=1)

HSP 1 Score: 101.679 bits (252), Expect = 1.115e-20
Identity = 76/292 (26.03%), Postives = 153/292 (52.40%), Query Frame = 3 
Query:    6 IIVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAV---NDSDSGAC-LINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFV---IWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLR-----ADIN-VEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTAL 842
            I++ FGT  N L+V V ++K  R+ + S F+  L++ D TV+ TG +      L+  N D+  +S+V C +H F+++ + D+S+W +M +T++RF+AV  P ++K   +     + ++    +  L NC  FWT         N + +  C   +  ++ + TK   W+    + +IP  +M+LCN+ +   + +     K+  +         +  T  ++ + +  + ++T   +   ++  R     AD + +  +S+ +++ +IL YS+++CNF+L+ L+G RFR AL
Sbjct:   52 ILIIFGTLGNALSVCVLSTKKLRNLTTSLFLIVLAIVDTTVLFTGLLRYWIRHLS--NVDIRHLSAVGCKVHVFLVYTSLDVSVWLLMAVTVERFLAVCFPFRVKQLCTIDVAKVTIVTIVAVLSLVNCHFFWTMGDVEYVIGNKTYTQRCTYADVKYYAFMTKIWPWIDFCIFSLIPLTLMLLCNISITVGLGRSYYRRKHLPLQGDHPASDVRMTTMTAMLMALSIVFIVTTVPIAAYLIGQREWTKNADSHTIAKLSLAWAIVNILQYSNNACNFLLYCLSGPRFRKAL 341
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A0K0PUJ9 (Orphan G-protein coupled receptor 49 OS=Platynereis dumerilii OX=6359 PE=2 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 4.245e-19
Identity = 86/326 (26.38%), Postives = 146/326 (44.79%), Query Frame = 3 
Query:    9 IVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLI---SISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPV-KLKWWKSKKNVLLIVIFFHFLALL----KNCPTFWTFTRSAVNDSDSGA---------CLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRA----DINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKC---HNKITSNSMDGLSIANKL 914
            I   G   N L ++V   + F+  +   ++  ++L+D  V++ G +P   SA      D++    +  V+C L +F+ +  GD+SIW +M  T+DRF+AV  P  K  + K  +       F+ F+ LL    KN   FW  TR  V  S  G          C     F  +E   R W+      ++P +V+++CNV +I     L +++ V +  +   +   T M + +  L  +      +  +I+ L      D + +   I  +V++ L Y +HS NF L+ L+G RFR  L     C   H   TS++ +     N L
Sbjct:   51 IFVVGVIGNVLILIVMMRRKFQGTTTCIYLRLMALADLLVLIIGMVPEWLSA-----NDIVIFKEVHPVTCKLEKFLQYTTGDVSIWILMCFTVDRFIAVCFPFSKTNFCKPGR-----ARFYGFIVLLAAIFKNLCVFW--TRGPVYHSSEGDNSSLVLVSNCGRPQPFTYFEKLIRPWIVFALISVLPFLVIVICNVMII---RALIESRVVTSGNKIQSNMEKTYMQMTLMCLSASFAFLVFITPSIVLLIGKPYWDNDSDSYIIAKAVNNQLTYVNHSINFFLYCLSGARFRKELVRTLICCVGHQPTTSSAWETTDGGNTL 361
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: T1FVT2 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Helobdella robusta OX=6412 GN=20212928 PE=3 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 8.086e-19
Identity = 85/322 (26.40%), Postives = 149/322 (46.27%), Query Frame = 3 
Query:    3 LIIVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSA-LNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKM--------------------NILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTIL------SLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNKITSNSM 887
            ++I   G   N L ++V   K F ++SA  ++  +++ D   ++T ++P  +++  N   P  +      C LHRF+ ++ GD+S+W ++  T+DRF+AV  P K + + + +  LL V     LA+ KN   FW  TR  V       C   S +  +E   R ++ L+T  ++P   +++ N F+I  +                    N L+  +  N  KE+      +        L ++     +   TI+      S   D N +   +I ++S++L   +HS NF L+ LTG RFR  LK+L  C  K+ S S+
Sbjct:   73 ILISPIGLVGNILTIVVMRKKPFLASSACVYLPAIAIFDILTLVT-SVPNEWTSWYNIQYPTWL------CCLHRFINYSTGDISVWILVAFTMDRFIAVCFPFKKQLFCTPRKALLTVFICTLLAVFKNAHVFW--TRGYVE--SKAKCTKVSRYRTFEDTIRPYIVLVTVSLLPFFCILIFNGFIIHHLLKSSKTKPKSFSGRRVSAAKNSLSTGEAHNTEKESGKRDKKSFYQTTAMCLSVSFAFLVLYFPTIVVQICKESKEFDKN-DTFEVIRNISNMLPLVNHSINFYLYCLTGVRFRNELKVLI-CGKKVESYSI 381
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: p2ry2.2 (purinergic receptor P2Y2 [Source:NCBI gene;Acc:107197486])

HSP 1 Score: 48.1358 bits (113), Expect = 5.809e-6
Identity = 69/304 (22.70%), Postives = 132/304 (43.42%), Query Frame = 3 
Query:   39 LNVLVFTSKLFRSNSASA---FMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPT-FWTFTRSAVND---SDSGACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINV-----EIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNKITSNSMDGLSIANKL 914
            LN +   + LFR    S    +M  L++ D   +LT      + A    + ++   S   C L RF+ +A    SI  +  I++ RF+ V  PV+   W S +   L+ +    + L+   P  +++ TR+A ND    D+    + ++F +Y T        + +++IP +V+++CN  ++ K   L +   V  +      K   +M I + + ++    P  +  ++      + V     E  SI Y V+  L  ++   + IL+ + G  FR ++       NK    +  G S++  L
Sbjct:   43 LNAIAMYAMLFRIKQWSPNTIYMINLTVCDTLYILTLPFLIYYYA----DKNVWPFSESFCKLIRFLFYANLYGSILFLSCISLHRFLGVCHPVRSMHWVSPRRARLVSVAVWVIVLVFQAPVLYFSRTRNAGNDLVCHDTTTEELFNHFLVYSTAIS-----VLFFVIPFLVVLVCNGLMVRK---LLEPTAVGGATSQRSKKKSVKMIIIVLLTFMLCFLPFHLTRSLYYCFRHLQVSCGLLEGSSIAYKVTRPLASANSCIDPILYFMAGQGFRRSINR----KNKKGYRTEKGKSLSTSL 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000079790.1 (SMESG000079790.1)

HSP 1 Score: 523.087 bits (1346), Expect = 0.000e+0
Identity = 279/300 (93.00%), Postives = 288/300 (96.00%), Query Frame = 3 
Query:    3 LIIVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNKITSNSMDGLSI 902
            +IIVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSL TYYIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSIAITILYITLITPAIVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILF++TG RFRT+LK L +  +K+   S +  +I
Sbjct:   16 IIIVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLTTYYIIPTIVMILCNVFVIWKMNILAKNQTVNASKETHYSKTLTRMSIAITILYITLITPAIVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFMITGQRFRTSLKSLLRIRSKVGPLSEENQTI 315
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000079761.1 (SMESG000079761.1)

HSP 1 Score: 186.422 bits (472), Expect = 1.655e-56
Identity = 117/303 (38.61%), Postives = 181/303 (59.74%), Query Frame = 3 
Query:   51 VFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTV--NASK------------ETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSL-RADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTA-LKLLFKCHNKITSNSMDGLSIANK 911
            +F    F+S+S + +M  L+++D  ++  G +P ++   N     L+  S   C+L RF++F  GD+S+W ++ ITIDR VAVV P++   WKS+KN ++I+I    L+L+KN P F+T +    N + +  C     F  YE K R ++SL+ YY+IPTI+M +C V +I KMN +AK   V  N  +              HYSK+LT+MSIAI IL++ L++P+I +WTI+S   A I  E +SI+Y  ++ILV+SHHS NF LF L+G RFR   L++  K +  I  +  + +  A +
Sbjct:   32 IFLRPNFKSSSITKYMRILAVTDTILIFVGIVPNVYEGFN--RKSLLIRSDAGCILQRFIMFFIGDISVWILIAITIDRLVAVVFPIQNTTWKSQKNSIVILIVVFSLSLIKNFPIFFTLS-VVTNTNGTRFCDTRERFAFYERKIRPFISLMMYYLIPTIIMTICTVVIILKMNRVAKKLDVMTNPKRRISMEINNVNFIRPHYSKSLTQMSIAINILFVLLLSPSIFIWTIISYWPASIQSEKISILYDSTNILVFSHHSLNFYLFFLSGPRFRKEVLQIFGKNYGSILDSKNESIKTAPE 331
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000079764.1 (SMESG000079764.1)

HSP 1 Score: 184.882 bits (468), Expect = 3.663e-56
Identity = 115/297 (38.72%), Postives = 180/297 (60.61%), Query Frame = 3 
Query:   51 VFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILA----------KNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNKITSNSMDGLSIANK 911
            +F  K FR+++ + ++  L+++D+ ++L   +P I+   +  +   I  +SV+CV+ R ++F AGD+S+W +  ITIDR VAVV P +  +WKS KN L ++I    L+LLKN P F  FT +++N +    C   ++F IYE   R  +SLI YY+IPTI M +C V ++ +M  +           +N       + HYSK+LT+MSIAI IL+  LITP+I +WT++S   DIN + +++ Y +++ILV+SHHS NF LF  TG RFR  + ++F   N   +N  D    +NK
Sbjct:   25 IFLRKNFRTSTITIYIRILAVADSVLLLAAAVPNIYRGFHG-DMGEIDRTSVACVIQRLIMFIAGDISVWTLTAITIDRLVAVVYPHQNSFWKSNKNTLFVLIVIFALSLLKNFPVF--FTLASINGT---RCAARTSFEIYEDSVRPIISLILYYLIPTITMTVCTVMILKEMRKIVGKIRAMSNPNRNSVSADYMKNHYSKSLTKMSIAINILFFVLITPSITIWTLMSYAKDINADAIALCYDITNILVFSHHSLNFYLFFFTGPRFRREVLIIF---NDKYANVTDSRDYSNK 312
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000079764.1 (SMESG000079764.1)

HSP 1 Score: 185.267 bits (469), Expect = 4.140e-56
Identity = 115/297 (38.72%), Postives = 180/297 (60.61%), Query Frame = 3 
Query:   51 VFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILA----------KNQTVNASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSLRADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNKITSNSMDGLSIANK 911
            +F  K FR+++ + ++  L+++D+ ++L   +P I+   +  +   I  +SV+CV+ R ++F AGD+S+W +  ITIDR VAVV P +  +WKS KN L ++I    L+LLKN P F  FT +++N +    C   ++F IYE   R  +SLI YY+IPTI M +C V ++ +M  +           +N       + HYSK+LT+MSIAI IL+  LITP+I +WT++S   DIN + +++ Y +++ILV+SHHS NF LF  TG RFR  + ++F   N   +N  D    +NK
Sbjct:   32 IFLRKNFRTSTITIYIRILAVADSVLLLAAAVPNIYRGFHG-DMGEIDRTSVACVIQRLIMFIAGDISVWTLTAITIDRLVAVVYPHQNSFWKSNKNTLFVLIVIFALSLLKNFPVF--FTLASINGT---RCAARTSFEIYEDSVRPIISLILYYLIPTITMTVCTVMILKEMRKIVGKIRAMSNPNRNSVSADYMKNHYSKSLTKMSIAINILFFVLITPSITIWTLMSYAKDINADAIALCYDITNILVFSHHSLNFYLFFFTGPRFRREVLIIF---NDKYANVTDSRDYSNK 319
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000011554.1 (SMESG000011554.1)

HSP 1 Score: 128.257 bits (321), Expect = 2.373e-34
Identity = 87/300 (29.00%), Postives = 151/300 (50.33%), Query Frame = 3 
Query:   21 GTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPTIFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVVIPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGA---------CLINSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVN------ASKETHYSKTLTRMSXXXXXXXXXXXXXXXVMWTILSL----RADINVEIMSIIYSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCH 863
            G   N L+ ++ + K   S S + +   L++ D+  ++TG IP     ++  N  + +I+  SC + RFV F  GD++ W ++L++ +RF+AVV P+KLK W +K   +L        + LKN   F +     +   D            C     +F+YE   R  +SLI +Y +  + + + N  +  +M    K    +      ++ +   SK+L +MS+ + IL++   TP+I +WT +SL      DIN  +M  +Y+++DIL Y  +S NF ++V++G RFR  L  L  C 
Sbjct:   39 GCLGNGLSFIILSRKSISSGSLAVYFRVLAICDSLALITGLIPVFIYQISDFN--MTTINDWSCRIQRFVNFFFGDVACWILILVSFERFIAVVYPLKLKSWSTKSKAILFTFLLFIPSCLKNFMAFVSLELKVITSKDEVGNQSSSEIKFCRGKKEYFLYENVVRPMISLIGFYFLTALAIFVTNAIISCRMRERLKTMREDTIGISSSNSQVKQSKSLLKMSLFVGILFLVFFTPSISIWTTMSLFTFYNVDINPNLMGFLYALTDILSYLQYSTNFFIYVISGRRFRKELINLIHCR 336
The following BLAST results are available for this feature:
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
SSTR15.384e-723.65somatostatin receptor 1 [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
frpr-61.429e-824.20FMRFamide Peptide Receptor family [Source:UniProt... [more]
frpr-83.707e-824.92FMRFamide Peptide Receptor family [Source:UniProt... [more]
frpr-119.527e-820.13FMRFamide Peptide Receptor family [Source:UniProt... [more]
frpr-104.148e-724.41FMRFamide Peptide Receptor family [Source:UniProt... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
AstA-R28.565e-625.34gene:FBgn0039595 transcript:FBtr0085316[more]
AstA-R28.565e-625.34gene:FBgn0039595 transcript:FBtr0336790[more]
CNMaR9.360e-624.00gene:FBgn0053696 transcript:FBtr0091684[more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Sstr13.533e-723.65somatostatin receptor 1 [Source:MGI Symbol;Acc:MGI... [more]
Sstr13.533e-723.65somatostatin receptor 1 [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|P28646|SSR1_RAT2.449e-623.65Somatostatin receptor type 1 OS=Rattus norvegicus ... [more]
sp|P30873|SSR1_MOUSE2.471e-623.65Somatostatin receptor type 1 OS=Mus musculus OX=10... [more]
sp|P30872|SSR1_HUMAN2.585e-623.65Somatostatin receptor type 1 OS=Homo sapiens OX=96... [more]
sp|Q49LX5|SSR1_CANLF2.609e-623.65Somatostatin receptor type 1 OS=Canis lupus famili... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3JYU63.994e-3028.16C5a anaphylatoxin chemotactic receptor 1 OS=Lingul... [more]
A0A0K0PVM12.340e-2428.10Orphan G-protein coupled receptor 1 OS=Platynereis... [more]
A0A1S3K5D91.115e-2026.03growth hormone secretagogue receptor type 1-like O... [more]
A0A0K0PUJ94.245e-1926.38Orphan G-protein coupled receptor 49 OS=Platynerei... [more]
T1FVT28.086e-1926.40G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
p2ry2.25.809e-622.70purinergic receptor P2Y2 [Source:NCBI gene;Acc:107... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000079790.10.000e+093.00SMESG000079790.1[more]
SMESG000079761.11.655e-5638.61SMESG000079761.1[more]
SMESG000079764.13.663e-5638.72SMESG000079764.1[more]
SMESG000079764.14.140e-5638.72SMESG000079764.1[more]
SMESG000011554.12.373e-3429.00SMESG000011554.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004445 ID=SMED30004445|Name=G_PROTEIN_RECEP_F1_2 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=933bp
ATCTAATCATCGTTACCTTCGGAACTTCAGCAAACTTTCTCAATGTTTTA
GTTTTCACAAGTAAGCTATTTAGGTCGAATTCAGCGTCGGCATTCATGAC
GTATTTGTCACTAAGTGACGCAACTGTCGTTTTGACGGGAACGATTCCGA
CAATATTTTCGGCTCTAAATCCTCTAAATCCCGATCTAATTTCCATAAGT
TCCGTAAGTTGTGTGCTACATAGATTTGTTCTGTTTGCCGCGGGAGATTT
ATCAATTTGGTGCGTGATGCTCATTACAATAGACCGGTTTGTGGCGGTTG
TTATTCCAGTGAAACTGAAATGGTGGAAATCGAAAAAAAATGTTTTGTTA
ATTGTGATATTTTTCCACTTTTTAGCATTGCTGAAAAACTGTCCAACATT
CTGGACATTCACTAGATCAGCTGTAAACGATTCTGATTCGGGTGCATGCT
TAATAAATTCTAACTTTTTCATTTATGAGACAAAATATCGGGCTTGGGTC
AGTTTGATTACTTATTACATAATACCAACTATAGTGATGATCCTATGTAA
TGTATTTGTTATATGGAAGATGAATATCTTGGCTAAAAATCAGACTGTAA
ATGCTTCTAAAGAAACTCATTATTCGAAAACTCTAACACGAATGTCAATT
GCGATAACCATTCTGTATATAACATTAATTACTCCAGCCATAGTTATGTG
GACAATTCTTAGCCTTCGTGCCGATATCAATGTGGAGATTATGTCCATCA
TATATTCCGTCAGTGATATTCTCGTTTATTCCCATCATAGCTGCAATTTC
ATTCTATTCGTGCTAACTGGAGGAAGATTTCGAACAGCACTGAAATTATT
ATTTAAATGTCATAATAAAATTACATCTAATTCTATGGATGGCTTGTCCA
TTGCAAATAAATTATGAACAAAATTTTGTGCAG
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protein sequence of SMED30004445-orf-1

>SMED30004445-orf-1 ID=SMED30004445-orf-1|Name=SMED30004445-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=305bp
LIIVTFGTSANFLNVLVFTSKLFRSNSASAFMTYLSLSDATVVLTGTIPT
IFSALNPLNPDLISISSVSCVLHRFVLFAAGDLSIWCVMLITIDRFVAVV
IPVKLKWWKSKKNVLLIVIFFHFLALLKNCPTFWTFTRSAVNDSDSGACL
INSNFFIYETKYRAWVSLITYYIIPTIVMILCNVFVIWKMNILAKNQTVN
ASKETHYSKTLTRMSIAITILYITLITPAIVMWTILSLRADINVEIMSII
YSVSDILVYSHHSCNFILFVLTGGRFRTALKLLFKCHNKITSNSMDGLSI
ANKL*
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protein sequence of SMED30004445-orf-2

>SMED30004445-orf-2 ID=SMED30004445-orf-2|Name=SMED30004445-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=157bp
MKKLEFIKHAPESESFTADLVNVQNVGQFFSNAKKWKNITINKTFFFDFH
HFSFTGITTATNRSIVMSITHQIDKSPAANRTNLCSTQLTELMEIRSGFR
GFRAENIVGIVPVKTTVASLSDKYVMNADAEFDLNSLLVKTKTLRKFAEV
PKVTMIR
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0007165signal transduction
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO:0004871signal transducer activity
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 76..98
score: 24.65
coord: 163..186
score: 17.17
coord: 250..276
score: 21.14
coord: 27..48
score: 20.38
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 10..261
e-value: 1.2E-15
score: 57.6
IPR000276G protein-coupled receptor, rhodopsin-likePROSITEPS00237G_PROTEIN_RECEP_F1_1coord: 82..98
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 1..292
e-value: 5.5E-39
score: 135.9
NoneNo IPR availablePANTHERPTHR46641:SF12CNMAMIDE RECEPTORcoord: 1..294
NoneNo IPR availablePANTHERPTHR46641FAMILY NOT NAMEDcoord: 1..294
NoneNo IPR availableCDDcd149787tmA_FMRFamide_R-likecoord: 1..279
e-value: 7.49272E-26
score: 101.941
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 1..291
NoneNo IPR availableTMHMMTMhelixcoord: 33..55
NoneNo IPR availableTMHMMTMhelixcoord: 248..270
NoneNo IPR availableTMHMMTMhelixcoord: 164..186
NoneNo IPR availableTMHMMTMhelixcoord: 70..92
NoneNo IPR availableTMHMMTMhelixcoord: 213..235
NoneNo IPR availableTMHMMTMhelixcoord: 113..135
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 9..268
score: 24.243