DNA polymerase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30004407 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of DNA polymerase vs. Ensembl Human
Match: POLD1 (DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175]) HSP 1 Score: 1131.32 bits (2925), Expect = 0.000e+0 Identity = 537/906 (59.27%), Postives = 690/906 (76.16%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++G+ + FL++TV +P LVA +R+L +G+ + G + A ++ ++DF +RFMVD+ + GC+W+ELP Y +R + EK + CQLE DV W ++ H E W IAP+R+LSFDIECAGRKG FP+ + DPVIQI ++ +R+GE EPF++ TL CAPI+GA V ++ E +LL+ WS FIR +DPD+ITGYN QNFDLPYLI+RA L V+ F LGR+ + S I +S QSKQ GRR K V M GR+ D+ +LLR++KLRSY+LNAVSFHFL EQKEDV H IITDLQNG+D+TR RLAVYCLKD+ L LRL+ +LMV+VN VEMARVTGVPLSYLLSRGQQ+KV+SQLLR+A E ++P +S+ G+++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+ + ++ GLTED +I+TP G FVK+SV+KGLLP IL L+ ARK+AK ELA ETDP +RQVLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY AKV+YGDTDSVMC FGVS+V EAMALG+EAA +SG F +PI+LEFEKVY+PYLLISKKRYAG+ + ++PD+ D+MDCKG+E VRRDNCPLVANL+ LR+LLI RD A++HAQ VI+DLLCNRIDISQL+I+KELT+ +Y KQ H ELA++++KRDPGSAP LGDRVPYVI + Y K+EDP++VL++++ IDT YYL+ QL PLLRIFEPI G+ A LL G+H K VG L + + CIGC+ VL + ++C C+P E +Y +E + +LE RFSRLWT+CQRC GSLH++V+C++RDCPIFY RKKV+K+L Q++++ R
Sbjct: 198 MFGYHGHGPSPFLRITVALPRLVAPARRLLEQGIRVAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYALRLK-EKATQCQLEADVLWSDVVSHPPEGPWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSNIRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMPVVKSEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPG-TAQKLGLTEDQFIRTPTGDEFVKTSVRKGLLPQILENLLSARKRAKAELAKETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVISDLLCNRIDISQLVITKELTRAASDYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVL-SHQGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQEQLLRRFG 1100 HSP 2 Score: 75.485 bits (184), Expect = 5.377e-13 Identity = 40/120 (33.33%), Postives = 58/120 (48.33%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY-----EIKETNPRS-----VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLKQRA-SQHQYAENLICKVEYCLKAS 547
+W R + P+ PLIFQQL+ID+Y + P S V R +G G S+ H+HGF PY Y PPGF EH G+ ++ LN + + + + + VE C + S
Sbjct: 78 RWLRPTPPALDPQTEPLIFQQLEIDHYVGPAQPVPGGPPPSRGSVPVLRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGPEHMGDLQRELNLAISRDSRGGRELTGPAVLAVELCSRES 197
BLAST of DNA polymerase vs. Ensembl Human
Match: POLD1 (DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175]) HSP 1 Score: 1131.32 bits (2925), Expect = 0.000e+0 Identity = 537/906 (59.27%), Postives = 690/906 (76.16%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++G+ + FL++TV +P LVA +R+L +G+ + G + A ++ ++DF +RFMVD+ + GC+W+ELP Y +R + EK + CQLE DV W ++ H E W IAP+R+LSFDIECAGRKG FP+ + DPVIQI ++ +R+GE EPF++ TL CAPI+GA V ++ E +LL+ WS FIR +DPD+ITGYN QNFDLPYLI+RA L V+ F LGR+ + S I +S QSKQ GRR K V M GR+ D+ +LLR++KLRSY+LNAVSFHFL EQKEDV H IITDLQNG+D+TR RLAVYCLKD+ L LRL+ +LMV+VN VEMARVTGVPLSYLLSRGQQ+KV+SQLLR+A E ++P +S+ G+++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+ + ++ GLTED +I+TP G FVK+SV+KGLLP IL L+ ARK+AK ELA ETDP +RQVLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY AKV+YGDTDSVMC FGVS+V EAMALG+EAA +SG F +PI+LEFEKVY+PYLLISKKRYAG+ + ++PD+ D+MDCKG+E VRRDNCPLVANL+ LR+LLI RD A++HAQ VI+DLLCNRIDISQL+I+KELT+ +Y KQ H ELA++++KRDPGSAP LGDRVPYVI + Y K+EDP++VL++++ IDT YYL+ QL PLLRIFEPI G+ A LL G+H K VG L + + CIGC+ VL + ++C C+P E +Y +E + +LE RFSRLWT+CQRC GSLH++V+C++RDCPIFY RKKV+K+L Q++++ R
Sbjct: 198 MFGYHGHGPSPFLRITVALPRLVAPARRLLEQGIRVAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYALRLK-EKATQCQLEADVLWSDVVSHPPEGPWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSNIRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMPVVKSEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPG-TAQKLGLTEDQFIRTPTGDEFVKTSVRKGLLPQILENLLSARKRAKAELAKETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVISDLLCNRIDISQLVITKELTRAASDYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVL-SHQGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQEQLLRRFG 1100 HSP 2 Score: 75.485 bits (184), Expect = 5.377e-13 Identity = 40/120 (33.33%), Postives = 58/120 (48.33%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY-----EIKETNPRS-----VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLKQRA-SQHQYAENLICKVEYCLKAS 547
+W R + P+ PLIFQQL+ID+Y + P S V R +G G S+ H+HGF PY Y PPGF EH G+ ++ LN + + + + + VE C + S
Sbjct: 78 RWLRPTPPALDPQTEPLIFQQLEIDHYVGPAQPVPGGPPPSRGSVPVLRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGPEHMGDLQRELNLAISRDSRGGRELTGPAVLAVELCSRES 197
BLAST of DNA polymerase vs. Ensembl Human
Match: POLD1 (DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175]) HSP 1 Score: 1131.32 bits (2925), Expect = 0.000e+0 Identity = 537/906 (59.27%), Postives = 690/906 (76.16%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++G+ + FL++TV +P LVA +R+L +G+ + G + A ++ ++DF +RFMVD+ + GC+W+ELP Y +R + EK + CQLE DV W ++ H E W IAP+R+LSFDIECAGRKG FP+ + DPVIQI ++ +R+GE EPF++ TL CAPI+GA V ++ E +LL+ WS FIR +DPD+ITGYN QNFDLPYLI+RA L V+ F LGR+ + S I +S QSKQ GRR K V M GR+ D+ +LLR++KLRSY+LNAVSFHFL EQKEDV H IITDLQNG+D+TR RLAVYCLKD+ L LRL+ +LMV+VN VEMARVTGVPLSYLLSRGQQ+KV+SQLLR+A E ++P +S+ G+++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+ + ++ GLTED +I+TP G FVK+SV+KGLLP IL L+ ARK+AK ELA ETDP +RQVLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY AKV+YGDTDSVMC FGVS+V EAMALG+EAA +SG F +PI+LEFEKVY+PYLLISKKRYAG+ + ++PD+ D+MDCKG+E VRRDNCPLVANL+ LR+LLI RD A++HAQ VI+DLLCNRIDISQL+I+KELT+ +Y KQ H ELA++++KRDPGSAP LGDRVPYVI + Y K+EDP++VL++++ IDT YYL+ QL PLLRIFEPI G+ A LL G+H K VG L + + CIGC+ VL + ++C C+P E +Y +E + +LE RFSRLWT+CQRC GSLH++V+C++RDCPIFY RKKV+K+L Q++++ R
Sbjct: 198 MFGYHGHGPSPFLRITVALPRLVAPARRLLEQGIRVAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYALRLK-EKATQCQLEADVLWSDVVSHPPEGPWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSNIRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMPVVKSEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPG-TAQKLGLTEDQFIRTPTGDEFVKTSVRKGLLPQILENLLSARKRAKAELAKETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVISDLLCNRIDISQLVITKELTRAASDYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVL-SHQGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQEQLLRRFG 1100 HSP 2 Score: 75.485 bits (184), Expect = 5.377e-13 Identity = 40/120 (33.33%), Postives = 58/120 (48.33%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY-----EIKETNPRS-----VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLKQRA-SQHQYAENLICKVEYCLKAS 547
+W R + P+ PLIFQQL+ID+Y + P S V R +G G S+ H+HGF PY Y PPGF EH G+ ++ LN + + + + + VE C + S
Sbjct: 78 RWLRPTPPALDPQTEPLIFQQLEIDHYVGPAQPVPGGPPPSRGSVPVLRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGPEHMGDLQRELNLAISRDSRGGRELTGPAVLAVELCSRES 197
BLAST of DNA polymerase vs. Ensembl Human
Match: POLD1 (DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175]) HSP 1 Score: 1117.45 bits (2889), Expect = 0.000e+0 Identity = 537/932 (57.62%), Postives = 690/932 (74.03%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKG--------------------------FYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++G+ + FL++TV +P LVA +R+L +G+ + G + A ++ ++DF +RFMVD+ + GC+W+ELP Y +R + EK + CQLE DV W ++ H E W IAP+R+LSFDIECAGRKG FP+ + DPVIQI ++ +R+GE EPF++ TL CAPI+GA V ++ E +LL+ WS FIR +DPD+ITGYN QNFDLPYLI+RA L V+ F LGR+ + S I +S QSKQ GRR K V M GR+ D+ +LLR++KLRSY+LNAVSFHFL EQKEDV H IITDLQNG+D+TR RLAVYCLKD+ L LRL+ +LMV+VN VEMARVTGVPLSYLLSRGQQ+KV+SQLLR+A E ++P +S+ G+++TGATVIEP+KG +YD PIATLDF+SLYPSIMMAHNLCYTTLL+ + ++ GLTED +I+TP G FVK+SV+KGLLP IL L+ ARK+AK ELA ETDP +RQVLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY AKV+YGDTDSVMC FGVS+V EAMALG+EAA +SG F +PI+LEFEKVY+PYLLISKKRYAG+ + ++PD+ D+MDCKG+E VRRDNCPLVANL+ LR+LLI RD A++HAQ VI+DLLCNRIDISQL+I+KELT+ +Y KQ H ELA++++KRDPGSAP LGDRVPYVI + Y K+EDP++VL++++ IDT YYL+ QL PLLRIFEPI G+ A LL G+H K VG L + + CIGC+ VL + ++C C+P E +Y +E + +LE RFSRLWT+CQRC GSLH++V+C++RDCPIFY RKKV+K+L Q++++ R
Sbjct: 198 MFGYHGHGPSPFLRITVALPRLVAPARRLLEQGIRVAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYALRLK-EKATQCQLEADVLWSDVVSHPPEGPWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSNIRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMPVVKSEGGEDYTGATVIEPLKGVRPQDRAGAAWELLALTPGRGCSPPRYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPG-TAQKLGLTEDQFIRTPTGDEFVKTSVRKGLLPQILENLLSARKRAKAELAKETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVISDLLCNRIDISQLVITKELTRAASDYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVL-SHQGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQEQLLRRFG 1126 HSP 2 Score: 75.485 bits (184), Expect = 4.901e-13 Identity = 40/120 (33.33%), Postives = 58/120 (48.33%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY-----EIKETNPRS-----VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLKQRA-SQHQYAENLICKVEYCLKAS 547
+W R + P+ PLIFQQL+ID+Y + P S V R +G G S+ H+HGF PY Y PPGF EH G+ ++ LN + + + + + VE C + S
Sbjct: 78 RWLRPTPPALDPQTEPLIFQQLEIDHYVGPAQPVPGGPPPSRGSVPVLRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGPEHMGDLQRELNLAISRDSRGGRELTGPAVLAVELCSRES 197
BLAST of DNA polymerase vs. Ensembl Human
Match: POLD1 (DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175]) HSP 1 Score: 1076.62 bits (2783), Expect = 0.000e+0 Identity = 518/906 (57.17%), Postives = 669/906 (73.84%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++G+ + FL++TV +P LVA +R+L +G+ + G + A ++ ++DF +RFMVD+ + GC+W+ELP Y +R + EK + CQLE DV W ++ H E W IAP+R+LSFDIECAGRKG FP+ + DPVIQI ++ +R+GE EPF++ TL CAPI+GA V ++ E +LL+ WS FIR +DPD+ITGYN QNFDLPYLI+RA L V+ F LGR+ + S I +S QSKQ GRR K V M GR+ D+ +LLR++KLRSY+LNAVSFHFL EQKEDV H IITDLQNG+D+TR RLAVYCLKD+ L LRL+ +LMV+VN VEMARVTGVPLSYLLSRGQQ+KV+SQLLR+A E ++P +S+ G+++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+ + ++ GLTED +I+TP G FVK+SV+KGLLP IL L+ ARK+AK ELA ETDP +RQVLDGRQLALK SVT FGR+MI+ TK++VES + NGY AKV+YGDTDSVMC FGVS+V EAMALG+EAA +SG F +PI+LEFEKVY+PYLLISKKRYAG+ + ++PD+ D+MDCKG+E VRRDNCPLVANL+ LR+LLI RD A++HAQ VI+DLLCNRIDISQL+I+KELT+ +Y KQ H ELA++++KRDPGSAP LGDRVPYVI + Y K+EDP++VL++++ IDT YYL+ QL PLLRIFEPI G+ A LL G+H K VG L + + CIGC+ VL + ++C C+P E +Y +E + +LE RFSRLWT+CQRC GSLH++V+C++RDCPIFY RKKV+K+L Q++++ R
Sbjct: 198 MFGYHGHGPSPFLRITVALPRLVAPARRLLEQGIRVAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYALRLK-EKATQCQLEADVLWSDVVSHPPEGPWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSNIRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMPVVKSEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPG-TAQKLGLTEDQFIRTPTGDEFVKTSVRKGLLPQILENLLSARKRAKAELAKETDPLRRQVLDGRQLALK------------------------SVTGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVISDLLCNRIDISQLVITKELTRAASDYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVL-SHQGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQEQLLRRFG 1076 HSP 2 Score: 75.485 bits (184), Expect = 4.813e-13 Identity = 40/120 (33.33%), Postives = 58/120 (48.33%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY-----EIKETNPRS-----VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLKQRA-SQHQYAENLICKVEYCLKAS 547
+W R + P+ PLIFQQL+ID+Y + P S V R +G G S+ H+HGF PY Y PPGF EH G+ ++ LN + + + + + VE C + S
Sbjct: 78 RWLRPTPPALDPQTEPLIFQQLEIDHYVGPAQPVPGGPPPSRGSVPVLRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGPEHMGDLQRELNLAISRDSRGGRELTGPAVLAVELCSRES 197
BLAST of DNA polymerase vs. Ensembl Celegans
Match: F10C2.4 (DNA polymerase delta catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P90829]) HSP 1 Score: 989.564 bits (2557), Expect = 0.000e+0 Identity = 494/915 (53.99%), Postives = 644/915 (70.38%), Query Frame = 3
Query: 726 DIYGF-SQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLAS-FDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLP--DYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKA--NGYV-HDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVL--RDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++Y F + K F+KV+ +L + L G+ + G N+ + ++++I+ V F+ + + GC WIE+P + +EK S CQ+EV V +I H ++ EW IAPIR LS DIEC GR+G FP+A DP+IQI+N++ GE+EPF++N F L TCAP+VG+++I E LLE W+ F+RE+DPDIITGYN NFDLPY+++RA L++ S LGR K S + ++ SKQMG R+NK++ + GRI FD+ ++LRD+KLRSY+LN+VS+ FL EQKEDV H II DLQ GD++TR RLA YCLKD+ L LRL++KLM ++NY+EMARVTGVP+++LL++GQQIK+LS +LR+ +F LP + S DG+ + GATVI+PI+GFY++PIATLDFASLYPSIM+AHNLCYTTLLKS + G+ +DYI+TP G YF S ++GLLP IL ++ ARK+AK ++ E D FKR V +GRQLALKISANSVYGFTGA G+LPCL IS SVTAFGR+MID TK VE + K +G DAKVIYGDTDSVM FGV TV +AM +G +AA+ +S F PIKLEFEKVY PYLLI+KKRYAG+Y+TKPD DKMDCKG+ETVRRDNCPLVA +L CL KLLI RD+ +AL A+ I+DLLCN+IDIS LIISKELTK+ ++Y +KQ H ELA ++KKRD GSAP+LGDRVPYV Y +AEDP +VL NNI +DT +YL NQL PL RIFEPI G + A + L+ GEH + QS VG L+ +T C+GCK+VL + E ++C HC+P I+ LE F RLWTECQ C+ ++ +V CS RDCPI+Y R+KV+ EL ++ER
Sbjct: 165 NLYYFRGADTKVPFVKVSGSTEAL-HKARMELKNGVNLMGKGPVNVGNLYESNINVIVMFLAKTNIVGCGWIEIPAGKCRILSNSEKSSRCQIEVTVPVKNLIVHESDGEWAGIAPIRTLSLDIECIGRRGVFPEAIKDPIIQIANLVKIEGEAEPFVRNCFVLGTCAPVVGSNIIQCVNEKVLLEKWAEFVREVDPDIITGYNILNFDLPYILDRAKVLSLPQVSHLGRQKEKGSVVRDAAISSKQMGSRVNKSIDIHGRIIFDVLQVVLRDYKLRSYTLNSVSYQFLSEQKEDVEHNIIPDLQRGDEQTRRRLAQYCLKDAYLPLRLLDKLMSIINYIEMARVTGVPMNFLLTKGQQIKILSMMLRRCKQNNFFLPVIEANSGDGEGYEGATVIDPIRGFYNEPIATLDFASLYPSIMIAHNLCYTTLLKSPQ-----GVENEDYIRTPSGQYFATKSKRRGLLPEILEDILAARKRAKNDMKNEKDEFKRMVYNGRQLALKISANSVYGFTGATVGKLPCLEISQSVTAFGRKMIDMTKLEVERIYKKGALDGKCPADAKVIYGDTDSVMVKFGVETVAQAMEIGLDAAKEVSKIFTPPIKLEFEKVYSPYLLINKKRYAGLYFTKPDVHDKMDCKGLETVRRDNCPLVAKVLGVCLEKLLIERDQQSALDFAKRTISDLLCNKIDISLLIISKELTKSGDKYQAKQAHVELAARMKKRDAGSAPRLGDRVPYVFVAAAKNVPAYERAEDPTFVLQNNIPLDTKHYLTNQLAKPLARIFEPILG-DRAEKILVEGEHTRVRTVVQSKVGGLAAFTTKSATCLGCKSVLPRAESENAVCKHCEPKLPTIFASRMNTMHELENHFGRLWTECQNCAKTMQDKVNCSARDCPIYYMREKVRNELSEASAVIERFG 1072
BLAST of DNA polymerase vs. Ensembl Celegans
Match: rev-3 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AX87]) HSP 1 Score: 228.794 bits (582), Expect = 2.283e-61 Identity = 179/631 (28.37%), Postives = 309/631 (48.97%), Query Frame = 3
Query: 1281 SNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRT-RHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPD----YQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLL-------------KSKESIR----EFGLTEDDYIK---------TPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYT-------KAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPI 3056
+ +I + D D++ GY T + R LLG SM + ++ ++ + GR+ ++ ++ D LR+Y L + + L ++ + + + G+ R+ + ++ LK S L + L+ ++ + EMARV G+ + +RG Q++V S LLR A +FV P ++ G ++EP Y P+ LDF SLYPS+++A+N CY+T+L +++E I ++ ++DD +K +P S FVK S ++G++P +L +++ AR K + + +++LD RQLALK+ AN YG+T A GR+PC ++ ++ GRE ++ + EMV+ G A+VIYGDTDS+ L ++V EA +G+ ++ P+ L+ EKVY +L +KKRYAG Y + +D KG+ETVRRD CP+VA +L L L+ S++ +++ +V+ +L + + S+ + KE + D + P ++A+ ++ P G+RVPYVI +Y+ A +P Y I+T YYL + L R+ + I
Sbjct: 307 AKWIVQYDVDVMIGYETIRLSWGFFFRR--------IKLLGSRISMDRALIDAYEDHIEVDDQEITVAPPKGRLLVSVWKVVRSDLALRNYDLGSAVANVLRKKIPMLDNAALMRRIKGERSAIRNDVHLHLLKLSSLNISLLTEMNWFLKNAEMARVYGIQFHEVWTRGSQLRVESMLLRLAHRMNFVAPSITHLQRNMMGSPEQLQLILEPQSKVYFDPVIVLDFQSLYPSMVIAYNYCYSTILGKIGNLVQMNDESRNREEIVLGAIKYHPSKDDIVKLVAYKEVCASPLASMFVKKSKREGVMPLLLREILAARIMVKSAMKRTKNKKLKRILDARQLALKLVANVSYGYTAANWSGRMPCAELADAILGKGRETLERSIEMVQ------RGDYGGAEVIYGDTDSMFVLVRGASVEEAFEIGRRIVDDVTNSNPDPVVLKLEKVYKGCVLETKKRYAGWMYEHENDEGSLDAKGIETVRRDTCPIVAEVLEKSL-GLIFSQNWKTFITYLNTVVLNL--PQENFSKFVFCKEY-RGDYSARAMVPQKKIAEARIRKCPSHITLRGERVPYVIIDGVTGSTVYSCVRSIDQFARNPEY------KINTFYYLNAHILAALRRVTDLI 913
BLAST of DNA polymerase vs. Ensembl Celegans
Match: rev-3 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AX87]) HSP 1 Score: 229.18 bits (583), Expect = 6.827e-61 Identity = 179/631 (28.37%), Postives = 309/631 (48.97%), Query Frame = 3
Query: 1281 SNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRT-RHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPD----YQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLL-------------KSKESIR----EFGLTEDDYIK---------TPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYT-------KAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPI 3056
+ +I + D D++ GY T + R LLG SM + ++ ++ + GR+ ++ ++ D LR+Y L + + L ++ + + + G+ R+ + ++ LK S L + L+ ++ + EMARV G+ + +RG Q++V S LLR A +FV P ++ G ++EP Y P+ LDF SLYPS+++A+N CY+T+L +++E I ++ ++DD +K +P S FVK S ++G++P +L +++ AR K + + +++LD RQLALK+ AN YG+T A GR+PC ++ ++ GRE ++ + EMV+ G A+VIYGDTDS+ L ++V EA +G+ ++ P+ L+ EKVY +L +KKRYAG Y + +D KG+ETVRRD CP+VA +L L L+ S++ +++ +V+ +L + + S+ + KE + D + P ++A+ ++ P G+RVPYVI +Y+ A +P Y I+T YYL + L R+ + I
Sbjct: 591 AKWIVQYDVDVMIGYETIRLSWGFFFRR--------IKLLGSRISMDRALIDAYEDHIEVDDQEITVAPPKGRLLVSVWKVVRSDLALRNYDLGSAVANVLRKKIPMLDNAALMRRIKGERSAIRNDVHLHLLKLSSLNISLLTEMNWFLKNAEMARVYGIQFHEVWTRGSQLRVESMLLRLAHRMNFVAPSITHLQRNMMGSPEQLQLILEPQSKVYFDPVIVLDFQSLYPSMVIAYNYCYSTILGKIGNLVQMNDESRNREEIVLGAIKYHPSKDDIVKLVAYKEVCASPLASMFVKKSKREGVMPLLLREILAARIMVKSAMKRTKNKKLKRILDARQLALKLVANVSYGYTAANWSGRMPCAELADAILGKGRETLERSIEMVQ------RGDYGGAEVIYGDTDSMFVLVRGASVEEAFEIGRRIVDDVTNSNPDPVVLKLEKVYKGCVLETKKRYAGWMYEHENDEGSLDAKGIETVRRDTCPIVAEVLEKSL-GLIFSQNWKTFITYLNTVVLNL--PQENFSKFVFCKEY-RGDYSARAMVPQKKIAEARIRKCPSHITLRGERVPYVIIDGVTGSTVYSCVRSIDQFARNPEY------KINTFYYLNAHILAALRRVTDLI 1197
BLAST of DNA polymerase vs. Ensembl Celegans
Match: pola-1 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:C7IVS4]) HSP 1 Score: 182.956 bits (463), Expect = 2.323e-46 Identity = 212/791 (26.80%), Postives = 359/791 (45.39%), Query Frame = 3
Query: 864 SFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKI----ICHSTEEWPSIAPIRILS-------------------FDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPF-IKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRS----KITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPD-----------YQSKDGDE-------FTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDS-FDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQ--SVIADLL--------CNRIDISQLIISKELTKTDEEYTS--KQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNN-IGIDTDYYLKNQLTNPLLRIFEPI 3056
+F+T + R +++ G WIEL Y K S C+ E +V +K+ S++ P + L+ F+ +C S D+ P ++ G S P+ I+ + V + E LL + I E +PD+I G++ + + L++R KL + +S + R+K RS KI S+S ++ GR+ D L + K RS+ L +S L ++ ++ I L D + L + D L LR++ +L + Y++++++ G S + G+ + LL D + PD +S++GDE ++G V+EP KG Y+ I LDF SLYPSI+ +N+CYTTL SK+S D+ + P +S+ +G+LP + +L+E R+ K + E + K++ +D RQ+ALK++ANS+YG G Q R +++ VTA GRE++ +K++VE GY V+YGDTDS+M +V A LG E ++++ K ++L+ + V + +L+ KK+ PD+ + + KG++ VRRD L + K+L +A+L+ + S I DLL + + ISK+LT+ E+Y Q H+ +AQ++ K + + D V YVI G + +A + +N+ + ID YYL Q+ + R+ EPI
Sbjct: 457 TFNTSVTPLERLLIEKKFMGPGWIEL----YNYSDPKAKTSNCKYEFEVDMEKMRNIKYLESSDAPPPTIKLLALNVVTTLNDRKDNEICMISMLFNPKCDLAHPSGDSKDLKPKCLVTKPP---GGSLPYDIQKRLETEKLSKFVKSVA----NEKALLTLFLAMINEDEPDMIVGHDL-SATIALLVSRLEKLKLPNWSRISRLK--RSINIGKIGHSKSGQWEL---------TAGRMMLDSKLAAMELVKSRSFDLTELSQQILGAERREIYANEIPQLY-VDSKDLISLINWSWNDLLLSLRIVVRLNALPLYIQISQIVGGIASRTMMGGRAERNEYLLLHAFEKADLIAPDKYNSSESKKKKEESQEGDEKKSGKAQYSGGLVLEPKKGLYETLILLLDFNSLYPSIIQEYNICYTTLEYSKDS--------DEQLSVP------QSTDIEGVLPREIRKLVECRRDVKSLMKSERNEAKKKQMDIRQMALKLTANSMYGCLGFQYSRFYAKPLAALVTAKGREILMHSKDLVEKM-----GY----SVVYGDTDSIMINTNSVDLVAAKKLGNEIKKAVN-KCHRLLELDLDGV-FKRMLLLKKKKYAALTINPDTKVEAKELKGLDIVRRDWSQLAKETGTAVVDKIL-----DASLTRDEMVSSIDDLLREIRAKLDSGTVPLEMFQISKQLTRNPEQYADVKAQCHAAVAQRLNKSGKFNL-RHNDIVEYVICEDGTDNPATQRAYHRTEMAENSALKIDLLYYLAQQIHPVVSRLVEPI 1192
BLAST of DNA polymerase vs. Ensembl Celegans
Match: pola-1 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:C7IVS4]) HSP 1 Score: 182.956 bits (463), Expect = 2.484e-46 Identity = 212/791 (26.80%), Postives = 359/791 (45.39%), Query Frame = 3
Query: 864 SFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKI----ICHSTEEWPSIAPIRILS-------------------FDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPF-IKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRS----KITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPD-----------YQSKDGDE-------FTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDS-FDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQ--SVIADLL--------CNRIDISQLIISKELTKTDEEYTS--KQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNN-IGIDTDYYLKNQLTNPLLRIFEPI 3056
+F+T + R +++ G WIEL Y K S C+ E +V +K+ S++ P + L+ F+ +C S D+ P ++ G S P+ I+ + V + E LL + I E +PD+I G++ + + L++R KL + +S + R+K RS KI S+S ++ GR+ D L + K RS+ L +S L ++ ++ I L D + L + D L LR++ +L + Y++++++ G S + G+ + LL D + PD +S++GDE ++G V+EP KG Y+ I LDF SLYPSI+ +N+CYTTL SK+S D+ + P +S+ +G+LP + +L+E R+ K + E + K++ +D RQ+ALK++ANS+YG G Q R +++ VTA GRE++ +K++VE GY V+YGDTDS+M +V A LG E ++++ K ++L+ + V + +L+ KK+ PD+ + + KG++ VRRD L + K+L +A+L+ + S I DLL + + ISK+LT+ E+Y Q H+ +AQ++ K + + D V YVI G + +A + +N+ + ID YYL Q+ + R+ EPI
Sbjct: 457 TFNTSVTPLERLLIEKKFMGPGWIEL----YNYSDPKAKTSNCKYEFEVDMEKMRNIKYLESSDAPPPTIKLLALNVVTTLNDRKDNEICMISMLFNPKCDLAHPSGDSKDLKPKCLVTKPP---GGSLPYDIQKRLETEKLSKFVKSVA----NEKALLTLFLAMINEDEPDMIVGHDL-SATIALLVSRLEKLKLPNWSRISRLK--RSINIGKIGHSKSGQWEL---------TAGRMMLDSKLAAMELVKSRSFDLTELSQQILGAERREIYANEIPQLY-VDSKDLISLINWSWNDLLLSLRIVVRLNALPLYIQISQIVGGIASRTMMGGRAERNEYLLLHAFEKADLIAPDKYNSSESKKKKEESQEGDEKKSGKAQYSGGLVLEPKKGLYETLILLLDFNSLYPSIIQEYNICYTTLEYSKDS--------DEQLSVP------QSTDIEGVLPREIRKLVECRRDVKSLMKSERNEAKKKQMDIRQMALKLTANSMYGCLGFQYSRFYAKPLAALVTAKGREILMHSKDLVEKM-----GY----SVVYGDTDSIMINTNSVDLVAAKKLGNEIKKAVN-KCHRLLELDLDGV-FKRMLLLKKKKYAALTINPDTKVEAKELKGLDIVRRDWSQLAKETGTAVVDKIL-----DASLTRDEMVSSIDDLLREIRAKLDSGTVPLEMFQISKQLTRNPEQYADVKAQCHAAVAQRLNKSGKFNL-RHNDIVEYVICEDGTDNPATQRAYHRTEMAENSALKIDLLYYLAQQIHPVVSRLVEPI 1192
BLAST of DNA polymerase vs. Ensembl Fly
Match: DNApol-delta (gene:FBgn0263600 transcript:FBtr0075522) HSP 1 Score: 1135.94 bits (2937), Expect = 0.000e+0 Identity = 545/915 (59.56%), Postives = 700/915 (76.50%), Query Frame = 3
Query: 723 LDIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKI---SFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDE-FTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLL--KSKESIREFGLTEDDYI-KTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRD--DEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERL 3437
L+I+G++ + K+ ++K++V +P VA R+L + + + + + +F+ +IDF +RFMVD+ + GC+WIELP+ + +R K S CQ+EVDV +D+ I H E EW +AP RILSFDIECAGRKG FP+A IDPVIQI+N+++R GE EPFI+N+FTLN CAPI+G+ V+ H E ++L+ WS F+RE+DPDI+TGYN NFD PYL+NRA L V+ F LGRIK++RS I E QSKQMGRR N+ V+ GR+ FDL +LLRD+KLRSY+LNAVS+HFL+EQKEDV H IITDLQNGD++TR RLA+YCLKD+ L LRL+ KLM +VNY+EMARVTGVPL LL+RGQQIKVLSQLLRKA + F++P Y S+ DE + GATVIEP +G+Y PI+TLDFASLYPSIMMAHNLCYTTL+ ++E +R+ +DD + +TP +YFVKS V++GLLP IL L+ ARK+AK +L +ETDPFKR+VLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVTA+GR MI+ TK VES + +ANGY ++A VIYGDTDSVM FGV T+ +M LG+EAA+ +S KF+ PIKLEFEKVYYPYLLI+KKRYAG+Y+T+PD++DKMDCKG+ETVRRDN PLVANL+N+CL+KLLI RD + A+++ + VIADLLCNRIDIS L+I+KEL KTD Y +KQ H ELA K+KKRDPG+AP+LGDRVPYVI Y KAEDP+YVL+N++ ID YYL+ QL+ PLLRIFEPI G A LL GEH ++ S VG L+ + K C+GCK+++ ++ +C HC+P +Y +E + LE FSRLWTECQRC SLH+EV+CSNRDCPIFY R+KV+ +L +Q++ + R
Sbjct: 176 LNIHGYNGDKKQRYIKISVTLPRFVAAASRLLKKEVIMSEIDFQDCRAFENNIDFDIRFMVDTDVVGCNWIELPMGHWRIRNSHSKPLPESRCQIEVDVAFDRFISHEPEGEWSKVAPFRILSFDIECAGRKGIFPEAKIDPVIQIANMVIRQGEREPFIRNVFTLNECAPIIGSQVLCHDKETQMLDKWSAFVREVDPDILTGYNINNFDFPYLLNRAAHLKVRNFEYLGRIKNIRSVIKEQMLQSKQMGRRENQYVNFEGRVPFDLLFVLLRDYKLRSYTLNAVSYHFLQEQKEDVHHSIITDLQNGDEQTRRRLAMYCLKDAYLPLRLLEKLMAIVNYMEMARVTGVPLESLLTRGQQIKVLSQLLRKAKTKGFIMPSYTSQGSDEQYEGATVIEPKRGYYADPISTLDFASLYPSIMMAHNLCYTTLVLGGTREKLRQQENLQDDQVERTPANNYFVKSEVRRGLLPEILESLLAARKRAKNDLKVETDPFKRKVLDGRQLALKISANSVYGFTGAQVGKLPCLEISGSVTAYGRTMIEMTKNEVESHYTQANGYENNAVVIYGDTDSVMVNFGVKTLERSMELGREAAELVSSKFVHPIKLEFEKVYYPYLLINKKRYAGLYFTRPDTYDKMDCKGIETVRRDNSPLVANLMNSCLQKLLIERDPDGAVAYVKQVIADLLCNRIDISHLVITKELAKTD--YAAKQAHVELAAKMKKRDPGTAPKLGDRVPYVICAAAKNTPAYQKAEDPLYVLENSVPIDATYYLEQQLSKPLLRIFEPILGDN-AESILLKGEHTRTRTVVTSKVGGLAGFMTKKTSCLGCKSLMPKGYEQACLCPHCEPRMSELYQKEVGAKRELEETFSRLWTECQRCQESLHEEVICSNRDCPIFYMRQKVRMDLDNQEKRVLRF 1087 HSP 2 Score: 69.3218 bits (168), Expect = 2.111e-11 Identity = 34/91 (37.36%), Postives = 48/91 (52.75%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNYEIK--------ETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQ 469
+W+R + P L FQQLD++NY + + P V R +G GNS+ HVHGF PY Y+E P F + HC + +K L+Q
Sbjct: 60 RWSRPPPPELDPSKHNLEFQQLDVENYLGQPLPGMPGAQIGPVPVVRMFGVTMEGNSVCCHVHGFCPYFYIEAPSQFEEHHCEKLQKALDQ 150
BLAST of DNA polymerase vs. Ensembl Fly
Match: DNApol-zeta (gene:FBgn0002891 transcript:FBtr0088831) HSP 1 Score: 280.796 bits (717), Expect = 6.757e-77 Identity = 226/756 (29.89%), Postives = 361/756 (47.75%), Query Frame = 3
Query: 1254 TEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFV--LPDYQSKD---GDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIR-----EFG-------------LTEDDYIK-TPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQ-VLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKM-DCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDE-EYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDN-NIGIDTDYYLKNQLTNPLLRIFEPIFGKELA------TRKLLHGEHVLSKFKQQSNVGA---LSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKEL 3407
+EAE E D DI GY + Y+I+RA L LL R+ + K+ + + ++ ++ + + GRI D++ ++ + L SY+ V +H L ++ + +T+ G TR + Y L+ L L+++L ++ EMA++ G+ +LSRG Q +V S +LR A ++ V P Q++ E+ A ++EP FY P+ LDF SLYPS+++A+N C++T L E + EFG L E D + +PCG FVK V++G+LP +L ++++ R+ K+ + + D Q +L RQL LK+ AN YG+T A GR+P + + SV + GRE ++ ++VE N +V+YGDTDS+ L EA +G+E A++++ P+KL+ EKVY P +L +KKRY G Y D + + KG+ETVRRD CP VA +L LR L ++D + ++ LL R ++ LI +KE + + T+ P EL +K ++DP P+ G+RVP++I ++ P +L N I+ YY+ + PL R + G + RKLL V + + GA +S+Y I C R + IC C N S LE + CQ C G L + C + DCP+ Y + ++EL
Sbjct: 1376 SEAEAFEALLALCERWDADIYAGYEIEMSSWGYVIDRAKHLCFNIAPLLSRVPTQ--KVRDFVDEDREQFTDLDVEMKLCGRILLDVWRLMRSEIALTSYTFENVMYHILHKRCPWHTAKSLTEW-FGSPCTRWIVMEYYLERVRGTLTLLDQLDLLGRTSEMAKLIGIQFYEVLSRGSQFRVESMMLRIAKPKNLVPLSPSVQARAHMRAPEYL-ALIMEPQSRFYADPLIVLDFQSLYPSMIIAYNYCFSTCLGRVEHLGGSSPFEFGASQLRVSRQMLQKLLEHDLVTVSPCGVVFVKREVREGILPRMLTEILDTRQMVKQSMKLHKDSSALQRILHSRQLGLKLMANVTYGYTAANFSGRMPSVEVGDSVVSKGRETLERAIKLVE------NNEEWKVRVVYGDTDSMFVLVPGRNRAEAFRIGEEIAKAVTEMNPQPVKLKLEKVYQPCMLQTKKRYVGYMYETADQEQPVYEAKGIETVRRDGCPAVAKMLEKVLRILFETQDVSKIKAYVCRQFTKLLSGRANLQDLIFAKEFRGLNGYKPTACVPALELTRKWMQKDPRHVPRRGERVPFIIVNGPPGMQLIRLVRSPHDILANEGHKINAIYYITKAIIPPLNRCLL-LIGANVHDWFASLPRKLLMTPAVGTANELAGARGAKSTISQYFSTTSCVIDCG---RQTKAGICPDCLKNATTCVVVLSDKTARLERGYQLTRQICQACCGRLGS-LQCDSLDCPVLYVLEGKRREL 2116
BLAST of DNA polymerase vs. Ensembl Fly
Match: DNApol-alpha180 (gene:FBgn0259113 transcript:FBtr0084115) HSP 1 Score: 169.859 bits (429), Expect = 3.335e-42 Identity = 195/821 (23.75%), Postives = 370/821 (45.07%), Query Frame = 3
Query: 780 PVPSLVATTKRVLVEGMTIPHYGYHNLAS-FDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTEEWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNII-VRFGESEPFIKNIFTLNTCA---PIV---------------GAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLE----EQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPD-----------------------YQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAI-ETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFD---KMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALS--HAQ--SVIADLLCNRIDISQLIISKELTKTDEEY--TSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKA---EDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFG 3062
P+P+L A K Y+++A F + RF++D + G W++ + + V P +S+C EV + K + ++ P + + R P + + IS + RF P + F + CA P V V H +E LL + ++ID D+I +++ + L + ++ L + +S +GR++ S+ G+R+ + H GR+ D+ + RSY L + L+ E+ E A ++ + G+ T+ L ++D+ +LRLM +L ++ +++ + G ++ L G+ + LL +++++PD Q+K + G V+EP++G Y+K + +DF SLYPSI+ +N+C+TT+ + ++ D+ P S + G+LP L +L+E+RK+ K+ +A + P + RQ+ALK++ANS+YG G R ++++ VT GRE++ T+++V+ + V+YGDTDS+M ++ + +G QS++ K ++L+ + V+ LL+ KK+YA + +K + + + KG++ VRRD L + L ++L + L HAQ + + + + +I+K+LT+T +EY ++ PH ++A ++ R+ + GD V YVI G + +A ++ D + +DT+YYL +Q+ + R+ E + G
Sbjct: 480 PLPNLSADKK-------------YNSIAHIFGATTNALERFLLDRKIKGPCWLQ--VTGFKVSPTP--MSWCNTEVTLTEPKNVELVQDKGKPAPPPPLTLLSLNV--RTSMNPKTSRNEICMISMLTHNRFHIDRPAPQPAFNRHMCALTRPAVVSWPLDLNFEMAKYKSTTVHKHDSERALLSWFLAQYQKIDADLIVTFDSMDCQLNVITDQIVALKIPQWSRMGRLRL-----------SQSFGKRLLE--HFVGRMVCDVKRSAEECIRARSYDLQTLCKQVLKLKESERMEVNADDLLEMYEKGESITK--LISLTMQDNSYLLRLMCELNIMPLALQITNICGNTMTRTLQGGRSERNEFLLLHAFHEKNYIVPDKKPVSKRSGAGDTDATLSGADATMQTKKKAAYAGGLVLEPMRGLYEKYVLLMDFNSLYPSIIQEYNICFTTVQQPVDA--------DELPTLP------DSKTEPGILPLQLKRLVESRKEVKKLMAAPDLSPELQMQYHIRQMALKLTANSMYGCLGFAHSRFFAQHLAALVTHKGREILTNTQQLVQK---------MNYDVVYGDTDSLMINTNITDYDQVYKIGHNIKQSVN-KLYKQLELDIDGVFGCLLLLKKKKYAAIKLSKDSKGNLRREQEHKGLDIVRRDWSQLAVMVGKAVLDEVLSEKPLEEKLDAVHAQLEKIKTQIAEGVVPLPLFVITKQLTRTPQEYANSASLPHVQVALRM-NRERNRRYKKGDMVDYVICLDGTTNAAMQRAYHLDELKTSEDKKLQLDTNYYLGHQIHPVVTRMVEVLEG 1241
BLAST of DNA polymerase vs. Ensembl Fly
Match: DNApol-epsilon255 (gene:FBgn0264326 transcript:FBtr0084408) HSP 1 Score: 52.373 bits (124), Expect = 3.135e-6 Identity = 54/171 (31.58%), Postives = 74/171 (43.27%), Query Frame = 3
Query: 954 YTVRPQTEKISFCQLEVDVQWDKIICHSTEEWPSIA----------PIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFG----ESEPFIKNI--FTLNTCAPIVGAHVI-PHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRAN--KLNVK---GFSLL 1400
Y VR + FC QW I C S E P+I P+ +L+FDIE FPDA D V+ IS +I G E N+ F G ++ + E +LL+ + + I E+ P II YN FD P++ RA L++K GFS L
Sbjct: 226 YHVRVSIDLRIFCG-----QWYNIRCRSGVELPTITCRPDILDRPEPV-VLAFDIETTKLPLKFPDAQTDQVMMISYMIDGQGYLITNREIISSNVDDFEYTPKPEFEGNFIVFNEENEMQLLQRFFDHIMEVRPHIIVTYNGDFFDWPFVETRAAVYDLDMKQEIGFSKL 390
BLAST of DNA polymerase vs. Ensembl Zebrafish
Match: pold1 (polymerase (DNA directed), delta 1, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-060429-1]) HSP 1 Score: 1153.66 bits (2983), Expect = 0.000e+0 Identity = 557/916 (60.81%), Postives = 695/916 (75.87%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRP-----QTE-----KISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
+Y + N FL++T+ +P LVA KR+L +G ++ + +F+ +IDF +RFMVDS + GC WIELP Y +R QT+ K+S CQ EVDV WD +I H E EW IAP+R+LSFDIECAGRKG FP+ ++DPVIQI++++ R GE EPFI+ +FTL +CA IVG+ ++ E +L+ W+ F+R +DPDIITGYN QNFDLPYL+NRA L V F LGR+ +S + +S QSKQMGRR NK ++M GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRL+ KLM V+NY+EMARVTGVPL+YLLSRGQQIKV+SQLLR+A +D V+P +++ G+++TGATVIEP KG+Y PIATLDF+SLYPSIMMAHNLCYTTLL+ K I + GL DD+IKTP G FVKSSV+KGLLP IL L+ ARK+AK EL ETDPFK+QVLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY DAKVIYGDTDSVM GV+TV EAM GKEAA+ +S F+ PIKLEFEKVYYPYLLI+KKRYAG+Y+ + + DKMDCKG+ETVRRDNCPLVANL+NTCL+ +LI RD + A++HA+ VI+DLLCNRIDISQL+I+KELT+T +EY KQ H ELA++++KRD GSAP LGDRVPYVI Y K+EDPIYVL+NNI IDT YYL+ QL+ PLLRIFEPI G+ A LL G+H K S VG L + + CIGC+ VL+ D ++C CK E +Y +E + +LE +FSRLWT+CQRC GSLH++VLC++RDCPIFY RKKVQK+L Q++++ R
Sbjct: 191 MYNYHGNKPHDFLRITMAMPRLVAPAKRLLEQGFKFANFATQSYQAFEANIDFEIRFMVDSNVVGCCWIELPKGKYQLREERREGQTDSKYPGKVSLCQYEVDVAWDSLISHPAEGEWQRIAPLRVLSFDIECAGRKGVFPEPEVDPVIQIASMVQRQGEKEPFIRTVFTLQSCASIVGSQILCFTQEKLMLQSWAEFMRTVDPDIITGYNIQNFDLPYLLNRAATLKVNMFPYLGRVWGCKSVLKDSSFQSKQMGRRENKTINMEGRVQFDLLQVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAYLPLRLLQKLMCVINYMEMARVTGVPLTYLLSRGQQIKVVSQLLRQAMKQDLVMPVVKTEGGEDYTGATVIEPEKGYYSVPIATLDFSSLYPSIMMAHNLCYTTLLQ-KSQIEKLGLGPDDFIKTPTGDLFVKSSVRKGLLPEILENLLSARKRAKAELKKETDPFKKQVLDGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEQTKQLVESRYTLDNGYQADAKVIYGDTDSVMVKLGVATVQEAMNQGKEAAEWVSSHFVPPIKLEFEKVYYPYLLINKKRYAGLYFSSSAEHHDKMDCKGIETVRRDNCPLVANLINTCLQNILIDRDPDGAVTHAKEVISDLLCNRIDISQLVITKELTRTAQEYAGKQAHVELAERMRKRDAGSAPNLGDRVPYVIIKAAKGVAAYMKSEDPIYVLENNIPIDTQYYLEQQLSKPLLRIFEPILGESKAESVLLKGDHTRCKTVLTSRVGGLMAFAQKRSTCIGCRAVLKTD-VAVCDFCKKRESELYQKEIAHLSTLEEKFSRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLDDQEKLVSRFG 1104 HSP 2 Score: 72.4034 bits (176), Expect = 3.237e-12 Identity = 42/135 (31.11%), Postives = 66/135 (48.89%), Query Frame = 2
Query: 116 DEDDVSMDEWNHEPEEICFEMESNTETVKETDEFS-----KWARQNMDVVKPEIMPLIFQQLDIDNY----------EIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTL 475
+E+ DE + E E E ++ + + D FS +W R + + P+ LIFQQ+D+D Y +++ P + R +G NGNS+ H+HGF PY YV P GF H +F++ LN +
Sbjct: 35 EEELALFDEMDMEVES--GEGQAGHDVIPVGDLFSTDLNPRWKRPHASPLHPKSDTLIFQQIDLDYYLGAAVAGMPGQVQGKVP--IVRMFGVTDNGNSVCCHIHGFAPYFYVPAPNGFTNAHLADFQRELNSVV 165
BLAST of DNA polymerase vs. Ensembl Zebrafish
Match: rev3l (REV3 like, DNA directed polymerase zeta catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-050302-55]) HSP 1 Score: 312.768 bits (800), Expect = 4.446e-87 Identity = 229/751 (30.49%), Postives = 368/751 (49.00%), Query Frame = 3
Query: 1257 EAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDL--VLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDF--VLPDYQSKDGDEFTGAT--VIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIR-----EFGLT------------EDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKREL-AIETDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKM-DCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSK-QPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVL-DNNIGIDTDYYLKNQLTNPLLRIFEPI------FGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKEL 3407
E EL E SN IR+ DPDI+ GY Q YL+ RA+ L V L R+ S+ + + G +H+ GRI +++ I+ + L +Y+ V+FH L ++ +H+ ++D D HR V S + ++L+ + ++ E+ARV G+ ++L+RG Q +V S +LR A ++ V P Q + V+EP FY + LDF SLYPSI++A+N CY+T L E++ +FG +D +P G FVKSSV++G+LP +L ++++ R K+ + A D ++LD RQL LK+ AN +G+T A GR+PC+ + S+ RE ++ +MV + K G A+V+YGDTDS+ L +T +A +G E A++++ PIKL+FEKVY P +L +KKRY G Y D + + D KG+ETVRRD CP V+ +L L+ L SRD + + Q ++ + + L +KE + P EL +++ D P++G+RVPYVI + P+ VL D ++ ++ YY+ Q+ PL RIF I + EL + + ++ + G +S+Y C C + + +CA C+ + + + E + +L C+ CSGS ++V C + DCPI Y +V + L
Sbjct: 2214 EKELFEEVSNIIRKYDPDILVGYEVQMHSWGYLLQRASTLGVNLCQQLSRVPG-DSQQNHFIPEKDEYGAETMTEIHITGRIILNIWRIMKTEAALNNYTFENVAFHLLHQRYPLYSHRTLSDWF---DTHLHRWKVMDHYVSRVCGTVQLLQQQDIIGRTSELARVFGIQFYHVLTRGSQYRVESMMLRVAKPMNYIPVTPSTQQRAQQRAAQCIPLVMEPESRFYSNSVIVLDFQSLYPSIVIAYNYCYSTCLGHIENLGTYDEFKFGCASLRVPPDLLYQLRNDITVSPNGVAFVKSSVRRGVLPRMLEEILKTRIMVKQSMKAYRNDKALSRLLDARQLGLKLIANVTFGYTSANFSGRMPCVEVGDSIVHKARETLERAIKMVNDT--KKWG----ARVVYGDTDSMFVLLKGATKEQAFKIGNEIAEAVTATNPKPIKLKFEKVYLPCILQTKKRYVGYMYESVDQENPVFDAKGIETVRRDGCPGVSKILERSLKLLFESRDISQVKQYVQRQCVKVVEGKASMQDLTFAKEYRGSGSYRPGACVPALELTRRMMAFDRRLEPRVGERVPYVIVYGSPGVPLIQLVRRPLEVLQDPSLRLNATYYITKQILPPLARIFNLIGVDVFSWYHELPRVQRAWSFTSSGRGEEGTKKGTISQYFTTL-HCPVCDELT---QLGVCARCRAEPQCVAVHLHQDLRLWESQQDQLLKICRSCSGSAERQVPCVSLDCPILYKLSRVNRNL 2950
BLAST of DNA polymerase vs. Ensembl Zebrafish
Match: rev3l (REV3 like, DNA directed polymerase zeta catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-050302-55]) HSP 1 Score: 311.612 bits (797), Expect = 1.020e-86 Identity = 229/751 (30.49%), Postives = 368/751 (49.00%), Query Frame = 3
Query: 1257 EAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDL--VLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDF--VLPDYQSKDGDEFTGAT--VIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIR-----EFGLT------------EDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKREL-AIETDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKM-DCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSK-QPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVL-DNNIGIDTDYYLKNQLTNPLLRIFEPI------FGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKEL 3407
E EL E SN IR+ DPDI+ GY Q YL+ RA+ L V L R+ S+ + + G +H+ GRI +++ I+ + L +Y+ V+FH L ++ +H+ ++D D HR V S + ++L+ + ++ E+ARV G+ ++L+RG Q +V S +LR A ++ V P Q + V+EP FY + LDF SLYPSI++A+N CY+T L E++ +FG +D +P G FVKSSV++G+LP +L ++++ R K+ + A D ++LD RQL LK+ AN +G+T A GR+PC+ + S+ RE ++ +MV + K G A+V+YGDTDS+ L +T +A +G E A++++ PIKL+FEKVY P +L +KKRY G Y D + + D KG+ETVRRD CP V+ +L L+ L SRD + + Q ++ + + L +KE + P EL +++ D P++G+RVPYVI + P+ VL D ++ ++ YY+ Q+ PL RIF I + EL + + ++ + G +S+Y C C + + +CA C+ + + + E + +L C+ CSGS ++V C + DCPI Y +V + L
Sbjct: 2028 EKELFEEVSNIIRKYDPDILVGYEVQMHSWGYLLQRASTLGVNLCQQLSRVPG-DSQQNHFIPEKDEYGAETMTEIHITGRIILNIWRIMKTEAALNNYTFENVAFHLLHQRYPLYSHRTLSDWF---DTHLHRWKVMDHYVSRVCGTVQLLQQQDIIGRTSELARVFGIQFYHVLTRGSQYRVESMMLRVAKPMNYIPVTPSTQQRAQQRAAQCIPLVMEPESRFYSNSVIVLDFQSLYPSIVIAYNYCYSTCLGHIENLGTYDEFKFGCASLRVPPDLLYQLRNDITVSPNGVAFVKSSVRRGVLPRMLEEILKTRIMVKQSMKAYRNDKALSRLLDARQLGLKLIANVTFGYTSANFSGRMPCVEVGDSIVHKARETLERAIKMVNDT--KKWG----ARVVYGDTDSMFVLLKGATKEQAFKIGNEIAEAVTATNPKPIKLKFEKVYLPCILQTKKRYVGYMYESVDQENPVFDAKGIETVRRDGCPGVSKILERSLKLLFESRDISQVKQYVQRQCVKVVEGKASMQDLTFAKEYRGSGSYRPGACVPALELTRRMMAFDRRLEPRVGERVPYVIVYGSPGVPLIQLVRRPLEVLQDPSLRLNATYYITKQILPPLARIFNLIGVDVFSWYHELPRVQRAWSFTSSGRGEEGTKKGTISQYFTTL-HCPVCDELT---QLGVCARCRAEPQCVAVHLHQDLRLWESQQDQLLKICRSCSGSAERQVPCVSLDCPILYKLSRVNRNL 2764
BLAST of DNA polymerase vs. Ensembl Zebrafish
Match: pola1 (polymerase (DNA directed), alpha 1 [Source:ZFIN;Acc:ZDB-GENE-030114-9]) HSP 1 Score: 193.356 bits (490), Expect = 2.103e-49 Identity = 219/852 (25.70%), Postives = 386/852 (45.31%), Query Frame = 3
Query: 765 LKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTEEWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNII-----VRFGESEPFIKNIFTL----NTCA-PIVGAHVIPHK--------TEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRR--INKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQ-----------SKDGDE-------------FTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETD--PFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAG-MYYTKPDS--FDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQS---VIADLLCN-RIDISQLIISKELTKTDEEYTSKQ--PHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDN-----NIGIDTDYYLKNQLTNPLLRIFEPIFGKE---LATRKLLHGEHVLSKFKQQSN 3131
+K + +PSL + K G T H N +S + F+++ + G W+++ + +P IS+C++E Q +I + P P+ ++S ++ P + ++ I+ ++ + P + F + N C P + K TE LL + + +IDPD++ G++ FDL L+ R N V +S +GR++ ++ ++G R + GR+ D+ + + +SY+L + L+ ++ V + I + + + L + + D+ L+L++M +L V+ +++ + G +S L G+ + LL DF++PD Q ++GD + G V++P GFYDK I LDF SLYPSI+ N+C+TT+ + + R+ TE+D + P S++ G+LP + +L+E R++ K +L E D P D RQ ALK++ANS+YG G R +++ VT GRE++ TKEMV+ + +VIYGDTDS+M + + E LG + ++ K ++++ + V+ LL+ KK+YA M + D K + KG++ VRRD C L N + ++L ++++ + + Q I + + N I ++ I K LTK ++Y K+ PH +A I + G + GD V YVI +D A Y L+ + +DT YYL Q+ + RI EPI G + +AT L H ++ +Q+ +
Sbjct: 452 VKYSAEIPSLPSDLK-----GTTFSHVFGTNTSSLE-------HFLLNRKIRGPCWLDVTTPQLSNQP----ISWCKVEAVAQKSDLISVVKDLSP--PPLVVMSISLKTVQN----PKTHQNEIVSIAALVHHTFPLDKAPPRPPFQTHFCVVSKPNDCVFPYDFKDAVRKKNGIVEIAGTERALLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLR---------RANMPKLGGRSGFAEKSATCGRLVCDIEISAKELIRCKSYNLTELVSQILKAERPVVPPENIRNFYSDSTHLLYLLELTWM-DAKLILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFHERDFIVPDKQFFKKAQQDLGEDEEGDSGKGKSNKTRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVERGATNTRK--KTEEDEDEIP---ELPDQSLEMGILPKEIRKLVERRRQVK-QLMKEPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKEMVQR---------MNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVN-KLYKLLEIDIDGVFKSLLLLKKKKYAALMVEPQGDGKYTTKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQNRDTIIENIQKHLIEIGEKVANGNIPLNMFEIHKSLTKEPQDYPDKKSLPHVHVALWINSQG-GKKVKAGDTVSYVI----CQDGSNLAASQRAYTLEQLQKQPGLNLDTQYYLSQQVHPVVGRICEPIEGIDAVLIATWLGLDPSHFRAQQQQRED 1250
BLAST of DNA polymerase vs. Ensembl Zebrafish
Match: pola1 (polymerase (DNA directed), alpha 1 [Source:ZFIN;Acc:ZDB-GENE-030114-9]) HSP 1 Score: 192.586 bits (488), Expect = 3.626e-49 Identity = 219/852 (25.70%), Postives = 386/852 (45.31%), Query Frame = 3
Query: 765 LKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTEEWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNII-----VRFGESEPFIKNIFTL----NTCA-PIVGAHVIPHK--------TEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRR--INKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQ-----------SKDGDE-------------FTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETD--PFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAG-MYYTKPDS--FDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQS---VIADLLCN-RIDISQLIISKELTKTDEEYTSKQ--PHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDN-----NIGIDTDYYLKNQLTNPLLRIFEPIFGKE---LATRKLLHGEHVLSKFKQQSN 3131
+K + +PSL + K G T H N +S + F+++ + G W+++ + +P IS+C++E Q +I + P P+ ++S ++ P + ++ I+ ++ + P + F + N C P + K TE LL + + +IDPD++ G++ FDL L+ R N V +S +GR++ ++ ++G R + GR+ D+ + + +SY+L + L+ ++ V + I + + + L + + D+ L+L++M +L V+ +++ + G +S L G+ + LL DF++PD Q ++GD + G V++P GFYDK I LDF SLYPSI+ N+C+TT+ + + R+ TE+D + P S++ G+LP + +L+E R++ K +L E D P D RQ ALK++ANS+YG G R +++ VT GRE++ TKEMV+ + +VIYGDTDS+M + + E LG + ++ K ++++ + V+ LL+ KK+YA M + D K + KG++ VRRD C L N + ++L ++++ + + Q I + + N I ++ I K LTK ++Y K+ PH +A I + G + GD V YVI +D A Y L+ + +DT YYL Q+ + RI EPI G + +AT L H ++ +Q+ +
Sbjct: 464 VKYSAEIPSLPSDLK-----GTTFSHVFGTNTSSLE-------HFLLNRKIRGPCWLDVTTPQLSNQP----ISWCKVEAVAQKSDLISVVKDLSP--PPLVVMSISLKTVQN----PKTHQNEIVSIAALVHHTFPLDKAPPRPPFQTHFCVVSKPNDCVFPYDFKDAVRKKNGIVEIAGTERALLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLR---------RANMPKLGGRSGFAEKSATCGRLVCDIEISAKELIRCKSYNLTELVSQILKAERPVVPPENIRNFYSDSTHLLYLLELTWM-DAKLILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFHERDFIVPDKQFFKKAQQDLGEDEEGDSGKGKSNKTRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVERGATNTRK--KTEEDEDEIP---ELPDQSLEMGILPKEIRKLVERRRQVK-QLMKEPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKEMVQR---------MNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVN-KLYKLLEIDIDGVFKSLLLLKKKKYAALMVEPQGDGKYTTKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQNRDTIIENIQKHLIEIGEKVANGNIPLNMFEIHKSLTKEPQDYPDKKSLPHVHVALWINSQG-GKKVKAGDTVSYVI----CQDGSNLAASQRAYTLEQLQKQPGLNLDTQYYLSQQVHPVVGRICEPIEGIDAVLIATWLGLDPSHFRAQQQQRED 1262
BLAST of DNA polymerase vs. Ensembl Xenopus
Match: plscr2 (phospholipid scramblase 2 [Source:Xenbase;Acc:XB-GENE-5819744]) HSP 1 Score: 1155.58 bits (2988), Expect = 0.000e+0 Identity = 557/917 (60.74%), Postives = 701/917 (76.44%), Query Frame = 3
Query: 726 DIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTE----------KISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++YG+ F+K+T+ +P L+A KR+L +G+ + H +++ +IDF +RFMVD+ + GC+WIELP Y +R +++ K+S Q+EVD+ W +I H E +W IAP+R+LSFDIECAGRKG FP+ D DPVIQI+N+++R GE + FI+N+FTL TC+ IVG+ V+ E LL+ W++F+R IDPDIITGYN QNFD+PYLINRA L V F LGRI+SM+S I +S QSKQMGRR NK ++ GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRLM KLM V+NY+EMARVTGVPLSYLLSRGQQIKV+SQLLR+A +D V+P +S+ G+++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+S SI ++GL+ +D+IKTP G FVK+S++KGLLP IL L+ ARK+AK EL ETDPFK++VLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY DAKVIYGDTDSVMC GV TVVEAM +G+EAA+ +S F PIKLEFEKVY+PYLLI+KKRYAG+Y+ + ++ DKMDCKG+ETVRRDNCPLVANL+NTCL+K+LI RD A+ HA+ VI+DLLCNRIDISQL+I+KELT+T +EY KQ H ELA++++KRDPGSAP LGDRVPYVI Y K+EDPIYVL+NNI IDT YYL+ QL PLLRIFEPI G+ A LL GEH K + VG L + + CIGCK L D ++C +CK E + +E LE +FSRLWT+CQRC GSLH++VLC++RDCPIFY RKKVQK+L Q++++ R
Sbjct: 181 NMYGYHGKKIIPFMKITMALPRLIAPAKRLLEQGLRFGRHPTHCYQAYEANIDFEIRFMVDNDIVGCNWIELPAGKYRLRKESQDEGPSKENPSKVSLAQIEVDISWADLISHPAEGDWQKIAPLRVLSFDIECAGRKGVFPEPDKDPVIQIANMVLRQGEKDAFIRNVFTLGTCSSIVGSQVLCFDREDALLKAWADFVRTIDPDIITGYNIQNFDMPYLINRAQTLKVPNFPFLGRIRSMKSVIRDSSFQSKQMGRRENKVINTEGRVQFDLLQVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAYLPLRLMEKLMCVINYMEMARVTGVPLSYLLSRGQQIKVVSQLLRQAMKQDLVMPVVKSEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLQSG-SIDKYGLSPEDFIKTPTGDCFVKASIRKGLLPEILENLLCARKRAKAELKKETDPFKQKVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTLDNGYKADAKVIYGDTDSVMCKLGVQTVVEAMEIGREAAEWVSSHFTPPIKLEFEKVYFPYLLINKKRYAGLYFSSSANTHDKMDCKGIETVRRDNCPLVANLINTCLQKILIDRDPMGAVEHAKDVISDLLCNRIDISQLVITKELTRTADEYAGKQAHVELAERMRKRDPGSAPNLGDRVPYVIIGAAKGVAAYMKSEDPIYVLENNIPIDTQYYLEQQLAKPLLRIFEPILGESKAESILLKGEHTRCKTVLTAKVGGLMAFAKKRSTCIGCKATLNHD-GAVCNYCKQRESELIQKEISQLSGLEEKFSRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLDDQEKLILRFG 1095 HSP 2 Score: 66.2402 bits (160), Expect = 3.755e-10 Identity = 36/116 (31.03%), Postives = 55/116 (47.41%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNYEIKETN--------PRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQ-TLKQRASQHQYAENLICKVEYCLK 541
KW R + + P+ L FQQ+++D+Y + P + R +G + GNS+ H+HGF PY YV GF +E +F+K LN +K S + V+ C K
Sbjct: 64 KWLRPPVSLTDPKEQTLCFQQVELDHYVGSHVSGMLGATQGPVPIIRMFGITEEGNSVCCHIHGFAPYFYVPCHTGFKQEDLSDFKKELNSAVIKDMRSNKDSISQAVLAVDVCHK 179
BLAST of DNA polymerase vs. Ensembl Xenopus
Match: plscr2 (phospholipid scramblase 2 [Source:Xenbase;Acc:XB-GENE-5819744]) HSP 1 Score: 1155.2 bits (2987), Expect = 0.000e+0 Identity = 557/917 (60.74%), Postives = 701/917 (76.44%), Query Frame = 3
Query: 726 DIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTE----------KISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++YG+ F+K+T+ +P L+A KR+L +G+ + H +++ +IDF +RFMVD+ + GC+WIELP Y +R +++ K+S Q+EVD+ W +I H E +W IAP+R+LSFDIECAGRKG FP+ D DPVIQI+N+++R GE + FI+N+FTL TC+ IVG+ V+ E LL+ W++F+R IDPDIITGYN QNFD+PYLINRA L V F LGRI+SM+S I +S QSKQMGRR NK ++ GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRLM KLM V+NY+EMARVTGVPLSYLLSRGQQIKV+SQLLR+A +D V+P +S+ G+++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+S SI ++GL+ +D+IKTP G FVK+S++KGLLP IL L+ ARK+AK EL ETDPFK++VLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY DAKVIYGDTDSVMC GV TVVEAM +G+EAA+ +S F PIKLEFEKVY+PYLLI+KKRYAG+Y+ + ++ DKMDCKG+ETVRRDNCPLVANL+NTCL+K+LI RD A+ HA+ VI+DLLCNRIDISQL+I+KELT+T +EY KQ H ELA++++KRDPGSAP LGDRVPYVI Y K+EDPIYVL+NNI IDT YYL+ QL PLLRIFEPI G+ A LL GEH K + VG L + + CIGCK L D ++C +CK E + +E LE +FSRLWT+CQRC GSLH++VLC++RDCPIFY RKKVQK+L Q++++ R
Sbjct: 191 NMYGYHGKKIIPFMKITMALPRLIAPAKRLLEQGLRFGRHPTHCYQAYEANIDFEIRFMVDNDIVGCNWIELPAGKYRLRKESQDEGPSKENPSKVSLAQIEVDISWADLISHPAEGDWQKIAPLRVLSFDIECAGRKGVFPEPDKDPVIQIANMVLRQGEKDAFIRNVFTLGTCSSIVGSQVLCFDREDALLKAWADFVRTIDPDIITGYNIQNFDMPYLINRAQTLKVPNFPFLGRIRSMKSVIRDSSFQSKQMGRRENKVINTEGRVQFDLLQVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAYLPLRLMEKLMCVINYMEMARVTGVPLSYLLSRGQQIKVVSQLLRQAMKQDLVMPVVKSEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLQSG-SIDKYGLSPEDFIKTPTGDCFVKASIRKGLLPEILENLLCARKRAKAELKKETDPFKQKVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTLDNGYKADAKVIYGDTDSVMCKLGVQTVVEAMEIGREAAEWVSSHFTPPIKLEFEKVYFPYLLINKKRYAGLYFSSSANTHDKMDCKGIETVRRDNCPLVANLINTCLQKILIDRDPMGAVEHAKDVISDLLCNRIDISQLVITKELTRTADEYAGKQAHVELAERMRKRDPGSAPNLGDRVPYVIIGAAKGVAAYMKSEDPIYVLENNIPIDTQYYLEQQLAKPLLRIFEPILGESKAESILLKGEHTRCKTVLTAKVGGLMAFAKKRSTCIGCKATLNHD-GAVCNYCKQRESELIQKEISQLSGLEEKFSRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLDDQEKLILRFG 1105 HSP 2 Score: 66.2402 bits (160), Expect = 3.448e-10 Identity = 51/190 (26.84%), Postives = 76/190 (40.00%), Query Frame = 2
Query: 53 FQKNKTYAPSSKISKFEVKNNDEDDVSMDEWNHEPEEICFEMESNTETVKETDEFS------------------KWARQNMDVVKPEIMPLIFQQLDIDNYEIKETN--------PRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQ-TLKQRASQHQYAENLICKVEYCLK 541
F++ K A S+ + D DD D + EE+ F E E E E KW R + + P+ L FQQ+++D+Y + P + R +G + GNS+ H+HGF PY YV GF +E +F+K LN +K S + V+ C K
Sbjct: 3 FKRKKGQASGLPASQTKKLRGDWDD---DAPSQFEEELAFMDEVEAEMAMELSEGQLSADILPVGKLISDNIPPKWLRPPVSLTDPKEQTLCFQQVELDHYVGSHVSGMLGATQGPVPIIRMFGITEEGNSVCCHIHGFAPYFYVPCHTGFKQEDLSDFKKELNSAVIKDMRSNKDSISQAVLAVDVCHK 189
BLAST of DNA polymerase vs. Ensembl Xenopus
Match: plscr2 (phospholipid scramblase 2 [Source:Xenbase;Acc:XB-GENE-5819744]) HSP 1 Score: 1121.69 bits (2900), Expect = 0.000e+0 Identity = 548/911 (60.15%), Postives = 686/911 (75.30%), Query Frame = 3
Query: 726 DIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIE----LPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++YG+ F+K+T+ +P L+A KR+L +G+ + H +++ +IDF +R+ C W LP+ V S Q+EVD+ W +I H E +W IAP+R+LSFDIECAGRKG FP+ D DPVIQI+N+++R GE + FI+N+FTL TC+ IVG+ V+ E LL+ W++F+R IDPDIITGYN QNFD+PYLINRA L V F LGRI+SM+S I +S QSKQMGRR NK ++ GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRLM KLM V+NY+EMARVTGVPLSYLLSRGQQIKV+SQLLR+A +D V+P +S+ G+++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+S SI ++GL+ +D+IKTP G FVK+S++KGLLP IL L+ ARK+AK EL ETDPFK++VLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY DAKVIYGDTDSVMC GV TVVEAM +G+EAA+ +S F PIKLEFEKVY+PYLLI+KKRYAG+Y+ + ++ DKMDCKG+ETVRRDNCPLVANL+NTCL+K+LI RD A+ HA+ VI+DLLCNRIDISQL+I+KELT+T +EY KQ H ELA++++KRDPGSAP LGDRVPYVI Y K+EDPIYVL+NNI IDT YYL+ QL PLLRIFEPI G+ A LL GEH K + VG L + + CIGCK L D ++C +CK E + +E LE +FSRLWT+CQRC GSLH++VLC++RDCPIFY RKKVQK+L Q++++ R
Sbjct: 191 NMYGYHGKKIIPFMKITMALPRLIAPAKRLLEQGLRFGRHPTHCYQAYEANIDFEIRYS-----HQCVWHHYRQYLPVGNRIV-------SLAQIEVDISWADLISHPAEGDWQKIAPLRVLSFDIECAGRKGVFPEPDKDPVIQIANMVLRQGEKDAFIRNVFTLGTCSSIVGSQVLCFDREDALLKAWADFVRTIDPDIITGYNIQNFDMPYLINRAQTLKVPNFPFLGRIRSMKSVIRDSSFQSKQMGRRENKVINTEGRVQFDLLQVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAYLPLRLMEKLMCVINYMEMARVTGVPLSYLLSRGQQIKVVSQLLRQAMKQDLVMPVVKSEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLQSG-SIDKYGLSPEDFIKTPTGDCFVKASIRKGLLPEILENLLCARKRAKAELKKETDPFKQKVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTLDNGYKADAKVIYGDTDSVMCKLGVQTVVEAMEIGREAAEWVSSHFTPPIKLEFEKVYFPYLLINKKRYAGLYFSSSANTHDKMDCKGIETVRRDNCPLVANLINTCLQKILIDRDPMGAVEHAKDVISDLLCNRIDISQLVITKELTRTADEYAGKQAHVELAERMRKRDPGSAPNLGDRVPYVIIGAAKGVAAYMKSEDPIYVLENNIPIDTQYYLEQQLAKPLLRIFEPILGESKAESILLKGEHTRCKTVLTAKVGGLMAFAKKRSTCIGCKATLNHD-GAVCNYCKQRESELIQKEISQLSGLEEKFSRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLDDQEKLILRFG 1087 HSP 2 Score: 66.2402 bits (160), Expect = 3.500e-10 Identity = 51/190 (26.84%), Postives = 76/190 (40.00%), Query Frame = 2
Query: 53 FQKNKTYAPSSKISKFEVKNNDEDDVSMDEWNHEPEEICFEMESNTETVKETDEFS------------------KWARQNMDVVKPEIMPLIFQQLDIDNYEIKETN--------PRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQ-TLKQRASQHQYAENLICKVEYCLK 541
F++ K A S+ + D DD D + EE+ F E E E E KW R + + P+ L FQQ+++D+Y + P + R +G + GNS+ H+HGF PY YV GF +E +F+K LN +K S + V+ C K
Sbjct: 3 FKRKKGQASGLPASQTKKLRGDWDD---DAPSQFEEELAFMDEVEAEMAMELSEGQLSADILPVGKLISDNIPPKWLRPPVSLTDPKEQTLCFQQVELDHYVGSHVSGMLGATQGPVPIIRMFGITEEGNSVCCHIHGFAPYFYVPCHTGFKQEDLSDFKKELNSAVIKDMRSNKDSISQAVLAVDVCHK 189
BLAST of DNA polymerase vs. Ensembl Xenopus
Match: plscr2 (phospholipid scramblase 2 [Source:Xenbase;Acc:XB-GENE-5819744]) HSP 1 Score: 1108.21 bits (2865), Expect = 0.000e+0 Identity = 543/917 (59.21%), Postives = 682/917 (74.37%), Query Frame = 3
Query: 726 DIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTE----------KISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++YG+ F+K+T+ +P L+A KR+L +G+ + H +++ +IDF +RFMVD+ + GC+WIELP Y +R +++ K+S Q+EVD+ W +I H E +W IAP+R+LSFDIECAGRKG FP+ D DPVIQI+N+++R GE + FI+N+FTL TC+ IVG+ V+ E LL+ W++F+R IDPDIITGYN QNFD+PYLINRA L V F LGRI+SM+S I +S QSKQMGRR NK ++ GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRLM KLM V+NY+EMARVTGVPLSYLLSRGQQIKV+SQLLR+ Q +E + + +YD PIATLDF+SLYPSIMMAHNLCYTTLL+S SI ++GL+ +D+IKTP G FVK+S++KGLLP IL L+ ARK+AK EL ETDPFK++VLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY DAKVIYGDTDSVMC GV TVVEAM +G+EAA+ +S F PIKLEFEKVY+PYLLI+KKRYAG+Y+ + ++ DKMDCKG+ETVRRDNCPLVANL+NTCL+K+LI RD A+ HA+ VI+DLLCNRIDISQL+I+KELT+T +EY KQ H ELA++++KRDPGSAP LGDRVPYVI Y K+EDPIYVL+NNI IDT YYL+ QL PLLRIFEPI G+ A LL GEH K + VG L + + CIGCK L D ++C +CK E + +E LE +FSRLWT+CQRC GSLH++VLC++RDCPIFY RKKVQK+L Q++++ R
Sbjct: 191 NMYGYHGKKIIPFMKITMALPRLIAPAKRLLEQGLRFGRHPTHCYQAYEANIDFEIRFMVDNDIVGCNWIELPAGKYRLRKESQDEGPSKENPSKVSLAQIEVDISWADLISHPAEGDWQKIAPLRVLSFDIECAGRKGVFPEPDKDPVIQIANMVLRQGEKDAFIRNVFTLGTCSSIVGSQVLCFDREDALLKAWADFVRTIDPDIITGYNIQNFDMPYLINRAQTLKVPNFPFLGRIRSMKSVIRDSSFQSKQMGRRENKVINTEGRVQFDLLQVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAYLPLRLMEKLMCVINYMEMARVTGVPLSYLLSRGQQIKVVSQLLRQVR---------QHNPQNEQLSCYCVS-CREYYDVPIATLDFSSLYPSIMMAHNLCYTTLLQSG-SIDKYGLSPEDFIKTPTGDCFVKASIRKGLLPEILENLLCARKRAKAELKKETDPFKQKVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTLDNGYKADAKVIYGDTDSVMCKLGVQTVVEAMEIGREAAEWVSSHFTPPIKLEFEKVYFPYLLINKKRYAGLYFSSSANTHDKMDCKGIETVRRDNCPLVANLINTCLQKILIDRDPMGAVEHAKDVISDLLCNRIDISQLVITKELTRTADEYAGKQAHVELAERMRKRDPGSAPNLGDRVPYVIIGAAKGVAAYMKSEDPIYVLENNIPIDTQYYLEQQLAKPLLRIFEPILGESKAESILLKGEHTRCKTVLTAKVGGLMAFAKKRSTCIGCKATLNHD-GAVCNYCKQRESELIQKEISQLSGLEEKFSRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLDDQEKLILRFG 1095 HSP 2 Score: 66.6254 bits (161), Expect = 2.887e-10 Identity = 51/190 (26.84%), Postives = 76/190 (40.00%), Query Frame = 2
Query: 53 FQKNKTYAPSSKISKFEVKNNDEDDVSMDEWNHEPEEICFEMESNTETVKETDEFS------------------KWARQNMDVVKPEIMPLIFQQLDIDNYEIKETN--------PRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQ-TLKQRASQHQYAENLICKVEYCLK 541
F++ K A S+ + D DD D + EE+ F E E E E KW R + + P+ L FQQ+++D+Y + P + R +G + GNS+ H+HGF PY YV GF +E +F+K LN +K S + V+ C K
Sbjct: 3 FKRKKGQASGLPASQTKKLRGDWDD---DAPSQFEEELAFMDEVEAEMAMELSEGQLSADILPVGKLISDNIPPKWLRPPVSLTDPKEQTLCFQQVELDHYVGSHVSGMLGATQGPVPIIRMFGITEEGNSVCCHIHGFAPYFYVPCHTGFKQEDLSDFKKELNSAVIKDMRSNKDSISQAVLAVDVCHK 189
BLAST of DNA polymerase vs. Ensembl Xenopus
Match: plscr2 (phospholipid scramblase 2 [Source:Xenbase;Acc:XB-GENE-5819744]) HSP 1 Score: 1095.88 bits (2833), Expect = 0.000e+0 Identity = 539/907 (59.43%), Postives = 674/907 (74.31%), Query Frame = 3
Query: 726 DIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++YG+ F+K+T+ +P L+A KR+L +G+ + H +++ +IDF +RFMVD+ + GC+WIELP Y +L+VD+ W +I H E +W IAP+R+LSFDIECAGRKG FP+ D DPVIQI+N+++R GE + FI+N+FTL TC+ IVG+ V+ E LL+ W++F+R IDPDIITGYN QNFD+PYLINRA L V F LGRI+SM+S I +S QSKQMGRR NK ++ GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRLM KLM V+NY+EMARVTGVPLSYLLSRGQQIKV+SQLLR+ Q +E + + +YD PIATLDF+SLYPSIMMAHNLCYTTLL+S SI ++GL+ +D+IKTP G FVK+S++KGLLP IL L+ ARK+AK EL ETDPFK++VLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY DAKVIYGDTDSVMC GV TVVEAM +G+EAA+ +S F PIKLEFEKVY+PYLLI+KKRYAG+Y+ + ++ DKMDCKG+ETVRRDNCPLVANL+NTCL+K+LI RD A+ HA+ VI+DLLCNRIDISQL+I+KELT+T +EY KQ H ELA++++KRDPGSAP LGDRVPYVI Y K+EDPIYVL+NNI IDT YYL+ QL PLLRIFEPI G+ A LL GEH K + VG L + + CIGCK L D ++C +CK E + +E LE +FSRLWT+CQRC GSLH++VLC++RDCPIFY RKKVQK+L Q++++ R
Sbjct: 194 NMYGYHGKKIIPFMKITMALPRLIAPAKRLLEQGLRFGRHPTHCYQAYEANIDFEIRFMVDNDIVGCNWIELPAGKY------------RLQVDISWADLISHPAEGDWQKIAPLRVLSFDIECAGRKGVFPEPDKDPVIQIANMVLRQGEKDAFIRNVFTLGTCSSIVGSQVLCFDREDALLKAWADFVRTIDPDIITGYNIQNFDMPYLINRAQTLKVPNFPFLGRIRSMKSVIRDSSFQSKQMGRRENKVINTEGRVQFDLLQVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAYLPLRLMEKLMCVINYMEMARVTGVPLSYLLSRGQQIKVVSQLLRQVR---------QHNPQNEQLSCYCVS-CREYYDVPIATLDFSSLYPSIMMAHNLCYTTLLQSG-SIDKYGLSPEDFIKTPTGDCFVKASIRKGLLPEILENLLCARKRAKAELKKETDPFKQKVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTLDNGYKADAKVIYGDTDSVMCKLGVQTVVEAMEIGREAAEWVSSHFTPPIKLEFEKVYFPYLLINKKRYAGLYFSSSANTHDKMDCKGIETVRRDNCPLVANLINTCLQKILIDRDPMGAVEHAKDVISDLLCNRIDISQLVITKELTRTADEYAGKQAHVELAERMRKRDPGSAPNLGDRVPYVIIGAAKGVAAYMKSEDPIYVLENNIPIDTQYYLEQQLAKPLLRIFEPILGESKAESILLKGEHTRCKTVLTAKVGGLMAFAKKRSTCIGCKATLNHD-GAVCNYCKQRESELIQKEISQLSGLEEKFSRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLDDQEKLILRFG 1076 HSP 2 Score: 65.855 bits (159), Expect = 4.276e-10 Identity = 36/116 (31.03%), Postives = 55/116 (47.41%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNYEIKETN--------PRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQ-TLKQRASQHQYAENLICKVEYCLK 541
KW R + + P+ L FQQ+++D+Y + P + R +G + GNS+ H+HGF PY YV GF +E +F+K LN +K S + V+ C K
Sbjct: 77 KWLRPPVSLTDPKEQTLCFQQVELDHYVGSHVSGMLGATQGPVPIIRMFGITEEGNSVCCHIHGFAPYFYVPCHTGFKQEDLSDFKKELNSAVIKDMRSNKDSISQAVLAVDVCHK 192
BLAST of DNA polymerase vs. Ensembl Mouse
Match: Pold1 (polymerase (DNA directed), delta 1, catalytic subunit [Source:MGI Symbol;Acc:MGI:97741]) HSP 1 Score: 1121.3 bits (2899), Expect = 0.000e+0 Identity = 527/906 (58.17%), Postives = 695/906 (76.71%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++G+ + FL++T+ +P L+A +R+L +G+ +P G + A ++ ++DF +RFMVD+ + GC+W+ELP Y VR +K + CQLEVDV W +I H E +W IAP+R+LSFDIECAGRKG FP+ + DPVIQI ++ +R+GE EPF++ TL CAPI+GA V ++ E +LL+ W++FI +DPD+ITGYN QNFDLPYLI+RA L V F LGR+ +RS I +S QS+Q+GRR +K + M GR+ D+ +LLR+HKLRSY+LNAVSFHFL EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRL+ +LMV+VN VEMARVTGVPL YLL+RGQQ+KV+SQLLR+A + ++P +++ +++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+ + ++ GL D++IKTP G FVKSSV+KGLLP IL L+ ARK+AK ELA ETDP +RQVLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY +AKV+YGDTDSVMC FGVS+V EAM+LG+EAA +S F +PI+LEFEKVY+PYLLISKKRYAG+ + ++ D+ DKMDCKG+E VRRDNCPLVANL+ + LR++L+ RD + A++HA+ VI+DLLCNRIDISQL+I+KELT+ +Y KQ H ELA++++KRDPGSAP LGDRVPYVI Y K+EDP++VL++++ IDT YYL+ QL PLLRIFEPI G+ A LL G+H K S VG L +T + CIGC++V+ D + ++C C+P E +Y +E + +LE RFSRLWT+CQRC GSLH++V+C++RDCPIFY RKKV+K+L Q+ +++R
Sbjct: 196 MFGYHGHGPSPFLRITLALPRLMAPARRLLEQGVRVPGLGTPSFAPYEANVDFEIRFMVDADIVGCNWLELPAGKY-VRRAEKKATLCQLEVDVLWSDVISHPPEGQWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEREEDLLQAWADFILAMDPDVITGYNIQNFDLPYLISRAQALKVDRFPFLGRVTGLRSNIRDSSFQSRQVGRRDSKVISMVGRVQMDMLQVLLREHKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAFLPLRLLERLMVLVNNVEMARVTGVPLGYLLTRGQQVKVVSQLLRQAMRQGLLMPVVKTEGSEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPG-AAQKLGLKPDEFIKTPTGDEFVKSSVRKGLLPQILENLLSARKRAKAELAQETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYDANAKVVYGDTDSVMCRFGVSSVAEAMSLGREAANWVSSHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRSDAHDKMDCKGLEAVRRDNCPLVANLVTSSLRRILVDRDPDGAVAHAKDVISDLLCNRIDISQLVITKELTRAAADYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIIGAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAESVLLRGDHTRCKTVLTSKVGGLLAFTKRRNCCIGCRSVI-DHQGAVCKFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQERLLQRFG 1098 HSP 2 Score: 73.559 bits (179), Expect = 1.351e-12 Identity = 38/121 (31.40%), Postives = 57/121 (47.11%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY----------EIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLK--QRASQHQYAENLICKVEYCLKAS 547
+W R + + P PLIFQQL+ID+Y + N + R +G G S+ H+ GF PY Y PPGF EH E ++ LN + QR + + + + +E C + S
Sbjct: 76 RWRRPTLRALDPSTEPLIFQQLEIDHYVGSAPPLPEGPLPSRNSVPILRAFGVTDEGFSVCCHIQGFAPYFYTPAPPGFGAEHLSELQQELNAAISRDQRGGK-ELSGPAVLAIELCSRES 195
BLAST of DNA polymerase vs. Ensembl Mouse
Match: Pold1 (polymerase (DNA directed), delta 1, catalytic subunit [Source:MGI Symbol;Acc:MGI:97741]) HSP 1 Score: 910.212 bits (2351), Expect = 0.000e+0 Identity = 428/711 (60.20%), Postives = 559/711 (78.62%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQK 2855
++G+ + FL++T+ +P L+A +R+L +G+ +P G + A ++ ++DF +RFMVD+ + GC+W+ELP Y VR +K + CQLEVDV W +I H E +W IAP+R+LSFDIECAGRKG FP+ + DPVIQI ++ +R+GE EPF++ TL CAPI+GA V ++ E +LL+ W++FI +DPD+ITGYN QNFDLPYLI+RA L V F LGR+ +RS I +S QS+Q+GRR +K + M GR+ D+ +LLR+HKLRSY+LNAVSFHFL EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRL+ +LMV+VN VEMARVTGVPL YLL+RGQQ+KV+SQLLR+A + ++P +++ +++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+ + ++ GL D++IKTP G FVKSSV+KGLLP IL L+ ARK+AK ELA ETDP +RQVLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY +AKV+YGDTDSVMC FGVS+V EAM+LG+EAA +S F +PI+LEFEKVY+PYLLISKKRYAG+ + ++ D+ DKMDCKG+E VRRDNCPLVANL+ + LR++L+ RD + A++HA+ VI+DLLCNRIDISQL+I+KELT+ +Y KQ H ELA++
Sbjct: 196 MFGYHGHGPSPFLRITLALPRLMAPARRLLEQGVRVPGLGTPSFAPYEANVDFEIRFMVDADIVGCNWLELPAGKY-VRRAEKKATLCQLEVDVLWSDVISHPPEGQWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEREEDLLQAWADFILAMDPDVITGYNIQNFDLPYLISRAQALKVDRFPFLGRVTGLRSNIRDSSFQSRQVGRRDSKVISMVGRVQMDMLQVLLREHKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAFLPLRLLERLMVLVNNVEMARVTGVPLGYLLTRGQQVKVVSQLLRQAMRQGLLMPVVKTEGSEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPG-AAQKLGLKPDEFIKTPTGDEFVKSSVRKGLLPQILENLLSARKRAKAELAQETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYDANAKVVYGDTDSVMCRFGVSSVAEAMSLGREAANWVSSHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRSDAHDKMDCKGLEAVRRDNCPLVANLVTSSLRRILVDRDPDGAVAHAKDVISDLLCNRIDISQLVITKELTRAAADYAGKQAHVELAER 904 HSP 2 Score: 73.9442 bits (180), Expect = 1.013e-12 Identity = 38/121 (31.40%), Postives = 57/121 (47.11%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY----------EIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLK--QRASQHQYAENLICKVEYCLKAS 547
+W R + + P PLIFQQL+ID+Y + N + R +G G S+ H+ GF PY Y PPGF EH E ++ LN + QR + + + + +E C + S
Sbjct: 76 RWRRPTLRALDPSTEPLIFQQLEIDHYVGSAPPLPEGPLPSRNSVPILRAFGVTDEGFSVCCHIQGFAPYFYTPAPPGFGAEHLSELQQELNAAISRDQRGGK-ELSGPAVLAIELCSRES 195
BLAST of DNA polymerase vs. Ensembl Mouse
Match: Rev3l (REV3 like, DNA directed polymerase zeta catalytic subunit [Source:MGI Symbol;Acc:MGI:1337131]) HSP 1 Score: 302.753 bits (774), Expect = 9.198e-84 Identity = 228/777 (29.34%), Postives = 384/777 (49.42%), Query Frame = 3
Query: 1224 IVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITES-QSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITD-LQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDF--VLPDYQSKDGDEFTGAT--VIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIRE-----FGLTE------------DDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKREL-AIETDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKM-DCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQ--PHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVL-DNNIGIDTDYYLKNQLTNPLLRIFEPI------FGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCK--PNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQ 3443
I G V E L + +N I+ DPDI+ GY Q YL+ RA L+V ++ R+ KI ++ G +++ GRI +L+ I+ + L +Y+ VSFH L ++ ++++D N D R ++ + + L+++ +L ++ EMAR+ G+ ++L+RG Q +V S +LR A ++ V P Q + ++EP FY + LDF SLYPSI++A+N C++T L E++ + FG T D +P G FVK SV+KG+LP +L ++++ R K+ + + + D ++L+ RQL LK+ AN +G+T A GR+PC+ + S+ RE ++ ++V + K G A+V+YGDTDS+ L +T ++ +G+E A++++ P+KL+FEKVY P +L +KKRY G Y D + + D KG+ETVRRD+CP V+ +L L+ L +RD + + Q L+ + I I +KE + Y P EL +K+ D S P++G+RVPYVI + P VL D + ++ YY+ Q+ PL RIF I + +EL + S+ + + G +S+Y C C ++ + IC+ C+ P +AI + + LE + +L C+ C+GS + + C + +CP+ + +V +EL + + L+Q
Sbjct: 2363 ITGLEVTYAADEKALFQEITNIIKRYDPDILLGYEIQMHSWGYLLQRAAALSVDLCQMISRVPD--DKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSIQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQIRHDVTVSPNGVAFVKPSVRKGVLPRMLEEILKTRLMVKQSMKSYKQDRALSRMLNARQLGLKLIANVTFGYTAANFSGRMPCIEVGDSIVHKARETLERAIKLVNDT--KKWG----ARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPRPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKEPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFIFAKEY-RGSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYVIIYGTPGLPLIQLIRRPAEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYQELPR---IQKATSSSRSELEGRKGTISQYFTTL-HCPVCDDLT---QHGICSKCRSQPQHVAIILNQEI--RELERKQEQLIKICRNCTGSFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQ 3121
BLAST of DNA polymerase vs. Ensembl Mouse
Match: Rev3l (REV3 like, DNA directed polymerase zeta catalytic subunit [Source:MGI Symbol;Acc:MGI:1337131]) HSP 1 Score: 302.753 bits (774), Expect = 9.198e-84 Identity = 228/777 (29.34%), Postives = 384/777 (49.42%), Query Frame = 3
Query: 1224 IVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITES-QSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITD-LQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDF--VLPDYQSKDGDEFTGAT--VIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIRE-----FGLTE------------DDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKREL-AIETDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKM-DCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQ--PHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVL-DNNIGIDTDYYLKNQLTNPLLRIFEPI------FGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCK--PNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQ 3443
I G V E L + +N I+ DPDI+ GY Q YL+ RA L+V ++ R+ KI ++ G +++ GRI +L+ I+ + L +Y+ VSFH L ++ ++++D N D R ++ + + L+++ +L ++ EMAR+ G+ ++L+RG Q +V S +LR A ++ V P Q + ++EP FY + LDF SLYPSI++A+N C++T L E++ + FG T D +P G FVK SV+KG+LP +L ++++ R K+ + + + D ++L+ RQL LK+ AN +G+T A GR+PC+ + S+ RE ++ ++V + K G A+V+YGDTDS+ L +T ++ +G+E A++++ P+KL+FEKVY P +L +KKRY G Y D + + D KG+ETVRRD+CP V+ +L L+ L +RD + + Q L+ + I I +KE + Y P EL +K+ D S P++G+RVPYVI + P VL D + ++ YY+ Q+ PL RIF I + +EL + S+ + + G +S+Y C C ++ + IC+ C+ P +AI + + LE + +L C+ C+GS + + C + +CP+ + +V +EL + + L+Q
Sbjct: 2363 ITGLEVTYAADEKALFQEITNIIKRYDPDILLGYEIQMHSWGYLLQRAAALSVDLCQMISRVPD--DKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSIQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQIRHDVTVSPNGVAFVKPSVRKGVLPRMLEEILKTRLMVKQSMKSYKQDRALSRMLNARQLGLKLIANVTFGYTAANFSGRMPCIEVGDSIVHKARETLERAIKLVNDT--KKWG----ARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPRPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKEPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFIFAKEY-RGSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYVIIYGTPGLPLIQLIRRPAEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYQELPR---IQKATSSSRSELEGRKGTISQYFTTL-HCPVCDDLT---QHGICSKCRSQPQHVAIILNQEI--RELERKQEQLIKICRNCTGSFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQ 3121
BLAST of DNA polymerase vs. Ensembl Mouse
Match: Pola1 (polymerase (DNA directed), alpha 1 [Source:MGI Symbol;Acc:MGI:99660]) HSP 1 Score: 193.741 bits (491), Expect = 1.621e-49 Identity = 186/642 (28.97%), Postives = 317/642 (49.38%), Query Frame = 3
Query: 1254 TEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQ------SKDGDE-------------------FTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVL--DGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDS----FDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQ----SVIADLLCNRIDISQLIISKELTKTDEEYTSKQ--PHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDP--IYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFG 3062
TE L+ + + +IDPDI+ G+N +F+L L+ R N+ V +S +GR++ RS + + S+S G R N GR+ D+ + +SY L+ + L+ ++ + + I ++ + + L + KD+ +L++M +L V+ +++ + G +S L G+ + LL ++++PD Q K GDE + G V++P GFYDK I LDF SLYPSI+ N+C+TT+ + +++ TED+ + +++ G+LP + +L+E RK+ K +L + D VL D RQ ALK++ANS+YG G R +++ VT GRE++ TK+MV+ + +VIYGDTDS+M + + E LG + ++ K ++++ + V+ LL+ KK+YA + +P S K + KG++ VRRD C L + N + ++L + ++ + + Q + ++L + +SQ I+K LTK ++Y ++ PH +A I + G + GD V YVI G +A P + LD N+ IDT YYL Q+ + RI EPI G
Sbjct: 618 TERTLIGFFLAKVHKIDPDILVGHNICSFELEVLLQRINECKVPYWSKIGRLR--RSNMPKLGSRSG-FGER-NATC---GRMICDVEISAKELIHCKSYHLSELVQQILKTERIVIPTENIRNMYSESSYLLYLLE-HIWKDARFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKKGRKKATYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVTSEVQK--ATEDE--EQEQIPELPDPNLEMGILPREIRKLVERRKQVK-QLMKQQDLNPDLVLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKDMVQK---------MNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVN-KLYKLLEIDIDAVFKSLLLLKKKKYAAL-VVEPTSDGNYITKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDRKSLPHVHVALWINSQG-GRKVKAGDTVSYVICQDGSNLTATQRAYAPEQLQKLD-NLAIDTQYYLAQQIHPVVARICEPIDG 1233
BLAST of DNA polymerase vs. UniProt/SwissProt
Match: sp|P28339|DPOD1_BOVIN (DNA polymerase delta catalytic subunit OS=Bos taurus OX=9913 GN=POLD1 PE=1 SV=1) HSP 1 Score: 1140.18 bits (2948), Expect = 0.000e+0 Identity = 537/906 (59.27%), Postives = 693/906 (76.49%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++G+ + FL++T+ +P L+A +R+L +G+ + G + A ++ ++DF +RFMVD+ + GC+W+ELP Y +RP+ K + CQLE DV W +I H E EW IAP+R+LSFDIECAGRKG FP+ + DPVIQI ++ +R+GE EPF++ TL CAPI+GA V ++ E +LL+ WS FIR +DPD+ITGYN QNFDLPYLI+RA L V GF LLGR+ +RS I ES QS+Q GRR +K V M GR+ D+ +LLR++KLRSY+LNAVSFHFL EQKEDV H IITDLQNG+D+TR RLAVYCLKD+ L LRL+ +LMV+VN +EMARVTGVPL YLLSRGQQ+KV+SQLLR+A + ++P +++ G+++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+ + ++ GLTED +IKTP G FVK+SV+KGLLP IL L+ ARK+AK ELA ETDP +RQVLDGRQLALK+SANSVYGFTGAQ GRLPCL IS SVT FGR+MI+ TK++VE+ + NGY AKV+YGDTDSVMC FGVS+V EAMALG+EAA +SG F +PI+LEFEKVY+PYLLISKKRYAG+ + ++PD+ D+MDCKG+E VRRDNCPLVANL+ LR+LLI RD + A++HAQ VI+DLLCNRIDISQL+I+KELT+ +Y KQ H ELA++++KRDPGSAP LGDRVPYVI + Y K+EDP++VL++++ IDT YYL+ QL PLLRIFEPI G+ A LL G+H K VG L + + CIGC+ VL + ++C C+P E +Y +E + +LE RFSRLWT+CQRC GSLH++V+C++RDCPIFY RKKV+K+L Q+ ++ R
Sbjct: 197 MFGYHGHGPSPFLRITLALPRLMAPARRLLEQGIRLAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYILRPEG-KATLCQLEADVLWSDVISHPPEGEWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEREEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVPGFPLLGRVIGLRSNIRESSFQSRQTGRRDSKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAFLPLRLLERLMVLVNAMEMARVTGVPLGYLLSRGQQVKVVSQLLRQAMRQGLLMPVVKTEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGAA-QKLGLTEDQFIKTPTGDEFVKASVRKGLLPQILENLLSARKRAKAELAKETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGRLPCLEISQSVTGFGRQMIEKTKQLVETKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPSGAVAHAQDVISDLLCNRIDISQLVITKELTRAAADYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVL-SHQGAVCKFCQPRESELYQKEVSHLSALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQERLLRRFG 1099 HSP 2 Score: 73.559 bits (179), Expect = 9.779e-12 Identity = 40/122 (32.79%), Postives = 60/122 (49.18%), Query Frame = 2
Query: 218 SKWARQNMDVVKPEIMPLIFQQLDIDNY-----EIKETNPRS-----VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLK--QRASQHQYAENLICKVEYCLKAS 547
++W R + P++ PLIFQQL+ID+Y + P S + R +G G S+ H+HGF PY Y PPGF EH E ++ L+ + QR + ++ VE C + S
Sbjct: 76 ARWLRPAPPALDPQMEPLIFQQLEIDHYVAPARPLPGAPPPSQDSVPILRAFGVTNEGVSVCCHIHGFAPYFYTPAPPGFGPEHLSELQRELSAAISRDQRGGKELTGPAVLA-VELCSRES 196
BLAST of DNA polymerase vs. UniProt/SwissProt
Match: sp|P54358|DPOD1_DROME (DNA polymerase delta catalytic subunit OS=Drosophila melanogaster OX=7227 GN=DNApol-delta PE=1 SV=2) HSP 1 Score: 1135.94 bits (2937), Expect = 0.000e+0 Identity = 545/915 (59.56%), Postives = 700/915 (76.50%), Query Frame = 3
Query: 723 LDIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKI---SFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDE-FTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLL--KSKESIREFGLTEDDYI-KTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRD--DEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERL 3437
L+I+G++ + K+ ++K++V +P VA R+L + + + + + +F+ +IDF +RFMVD+ + GC+WIELP+ + +R K S CQ+EVDV +D+ I H E EW +AP RILSFDIECAGRKG FP+A IDPVIQI+N+++R GE EPFI+N+FTLN CAPI+G+ V+ H E ++L+ WS F+RE+DPDI+TGYN NFD PYL+NRA L V+ F LGRIK++RS I E QSKQMGRR N+ V+ GR+ FDL +LLRD+KLRSY+LNAVS+HFL+EQKEDV H IITDLQNGD++TR RLA+YCLKD+ L LRL+ KLM +VNY+EMARVTGVPL LL+RGQQIKVLSQLLRKA + F++P Y S+ DE + GATVIEP +G+Y PI+TLDFASLYPSIMMAHNLCYTTL+ ++E +R+ +DD + +TP +YFVKS V++GLLP IL L+ ARK+AK +L +ETDPFKR+VLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVTA+GR MI+ TK VES + +ANGY ++A VIYGDTDSVM FGV T+ +M LG+EAA+ +S KF+ PIKLEFEKVYYPYLLI+KKRYAG+Y+T+PD++DKMDCKG+ETVRRDN PLVANL+N+CL+KLLI RD + A+++ + VIADLLCNRIDIS L+I+KEL KTD Y +KQ H ELA K+KKRDPG+AP+LGDRVPYVI Y KAEDP+YVL+N++ ID YYL+ QL+ PLLRIFEPI G A LL GEH ++ S VG L+ + K C+GCK+++ ++ +C HC+P +Y +E + LE FSRLWTECQRC SLH+EV+CSNRDCPIFY R+KV+ +L +Q++ + R
Sbjct: 176 LNIHGYNGDKKQRYIKISVTLPRFVAAASRLLKKEVIMSEIDFQDCRAFENNIDFDIRFMVDTDVVGCNWIELPMGHWRIRNSHSKPLPESRCQIEVDVAFDRFISHEPEGEWSKVAPFRILSFDIECAGRKGIFPEAKIDPVIQIANMVIRQGEREPFIRNVFTLNECAPIIGSQVLCHDKETQMLDKWSAFVREVDPDILTGYNINNFDFPYLLNRAAHLKVRNFEYLGRIKNIRSVIKEQMLQSKQMGRRENQYVNFEGRVPFDLLFVLLRDYKLRSYTLNAVSYHFLQEQKEDVHHSIITDLQNGDEQTRRRLAMYCLKDAYLPLRLLEKLMAIVNYMEMARVTGVPLESLLTRGQQIKVLSQLLRKAKTKGFIMPSYTSQGSDEQYEGATVIEPKRGYYADPISTLDFASLYPSIMMAHNLCYTTLVLGGTREKLRQQENLQDDQVERTPANNYFVKSEVRRGLLPEILESLLAARKRAKNDLKVETDPFKRKVLDGRQLALKISANSVYGFTGAQVGKLPCLEISGSVTAYGRTMIEMTKNEVESHYTQANGYENNAVVIYGDTDSVMVNFGVKTLERSMELGREAAELVSSKFVHPIKLEFEKVYYPYLLINKKRYAGLYFTRPDTYDKMDCKGIETVRRDNSPLVANLMNSCLQKLLIERDPDGAVAYVKQVIADLLCNRIDISHLVITKELAKTD--YAAKQAHVELAAKMKKRDPGTAPKLGDRVPYVICAAAKNTPAYQKAEDPLYVLENSVPIDATYYLEQQLSKPLLRIFEPILGDN-AESILLKGEHTRTRTVVTSKVGGLAGFMTKKTSCLGCKSLMPKGYEQACLCPHCEPRMSELYQKEVGAKRELEETFSRLWTECQRCQESLHEEVICSNRDCPIFYMRQKVRMDLDNQEKRVLRF 1087 HSP 2 Score: 69.3218 bits (168), Expect = 2.116e-10 Identity = 34/91 (37.36%), Postives = 48/91 (52.75%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNYEIK--------ETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQ 469
+W+R + P L FQQLD++NY + + P V R +G GNS+ HVHGF PY Y+E P F + HC + +K L+Q
Sbjct: 60 RWSRPPPPELDPSKHNLEFQQLDVENYLGQPLPGMPGAQIGPVPVVRMFGVTMEGNSVCCHVHGFCPYFYIEAPSQFEEHHCEKLQKALDQ 150
BLAST of DNA polymerase vs. UniProt/SwissProt
Match: sp|P28340|DPOD1_HUMAN (DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2) HSP 1 Score: 1131.32 bits (2925), Expect = 0.000e+0 Identity = 537/906 (59.27%), Postives = 690/906 (76.16%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++G+ + FL++TV +P LVA +R+L +G+ + G + A ++ ++DF +RFMVD+ + GC+W+ELP Y +R + EK + CQLE DV W ++ H E W IAP+R+LSFDIECAGRKG FP+ + DPVIQI ++ +R+GE EPF++ TL CAPI+GA V ++ E +LL+ WS FIR +DPD+ITGYN QNFDLPYLI+RA L V+ F LGR+ + S I +S QSKQ GRR K V M GR+ D+ +LLR++KLRSY+LNAVSFHFL EQKEDV H IITDLQNG+D+TR RLAVYCLKD+ L LRL+ +LMV+VN VEMARVTGVPLSYLLSRGQQ+KV+SQLLR+A E ++P +S+ G+++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+ + ++ GLTED +I+TP G FVK+SV+KGLLP IL L+ ARK+AK ELA ETDP +RQVLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY AKV+YGDTDSVMC FGVS+V EAMALG+EAA +SG F +PI+LEFEKVY+PYLLISKKRYAG+ + ++PD+ D+MDCKG+E VRRDNCPLVANL+ LR+LLI RD A++HAQ VI+DLLCNRIDISQL+I+KELT+ +Y KQ H ELA++++KRDPGSAP LGDRVPYVI + Y K+EDP++VL++++ IDT YYL+ QL PLLRIFEPI G+ A LL G+H K VG L + + CIGC+ VL + ++C C+P E +Y +E + +LE RFSRLWT+CQRC GSLH++V+C++RDCPIFY RKKV+K+L Q++++ R
Sbjct: 198 MFGYHGHGPSPFLRITVALPRLVAPARRLLEQGIRVAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYALRLK-EKATQCQLEADVLWSDVVSHPPEGPWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSNIRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMPVVKSEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPG-TAQKLGLTEDQFIRTPTGDEFVKTSVRKGLLPQILENLLSARKRAKAELAKETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVISDLLCNRIDISQLVITKELTRAASDYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVL-SHQGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQEQLLRRFG 1100 HSP 2 Score: 75.485 bits (184), Expect = 2.582e-12 Identity = 40/120 (33.33%), Postives = 58/120 (48.33%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY-----EIKETNPRS-----VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLKQRA-SQHQYAENLICKVEYCLKAS 547
+W R + P+ PLIFQQL+ID+Y + P S V R +G G S+ H+HGF PY Y PPGF EH G+ ++ LN + + + + + VE C + S
Sbjct: 78 RWLRPTPPALDPQTEPLIFQQLEIDHYVGPAQPVPGGPPPSRGSVPVLRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGPEHMGDLQRELNLAISRDSRGGRELTGPAVLAVELCSRES 197
BLAST of DNA polymerase vs. UniProt/SwissProt
Match: sp|P97283|DPOD1_MESAU (DNA polymerase delta catalytic subunit OS=Mesocricetus auratus OX=10036 GN=POLD1 PE=2 SV=1) HSP 1 Score: 1122.07 bits (2901), Expect = 0.000e+0 Identity = 528/906 (58.28%), Postives = 695/906 (76.71%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++G+ + FL++T+ +P LVA +R+L +G+ +P G + A ++ ++DF +RFMVD+ + GC+W+ELP Y R + +K + CQLEVDV W +I H E +W IAP+R+LSFDIECAGRKG FP+ + DPVIQI ++ +R+GE EPF++ TL CAPI+GA V ++ E +LL+ W NFI +DPD+ITGYN QNFDLPYLI+RA L V F LGR+ +RS I +S QS+Q+GRR +K V M GR+ D+ +LLR+HKLRSY+LNAVSFHFL EQKEDV H IITDLQNG+++TR RLAVYCL+D+ L LRL+ +LMV+VN VEMARVTGVPL YLLSRGQQ+KV+SQLLR+A + ++P +++ G+++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+ + ++ GL D++IKTP G FVKSSV+KGLLP IL L+ ARK+AK ELA ETDP +RQVLDGRQLALK+SANSVYGFTGA+ G+LPCL IS SVT FGR+MI+ TK++VES + NGY +AKV+YGDTDSVMC FGVS+V EAM+LG+EAA +S F +PI+LEFEKVY+PYLLISKKRYAG+ + ++PD+ D+MDCKG+E VRRDNCPLVANL+ + LR++L+ RD + A++HA+ VI+DLLCNRIDISQL+I+KELT+ +Y KQ H ELA++++KRDPGSAP LGDRVPYVI Y K+EDP++VL++++ IDT YYL QL PLLRIFEPI G+ A LL G+H K S VG L +T + CIGC++V+ + + ++C C+P E +Y +E + +LE RFSRLWT+CQRC GSLH++V+C++RDCPIFY RKKV+K+L Q+ +++R
Sbjct: 194 MFGYHGHGPSPFLRITLALPRLVAPARRLLEQGIRVPGLGTPSFAPYEANVDFEIRFMVDADIVGCNWLELPAGKYVWRTE-KKATQCQLEVDVLWSDVISHPPEGQWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEREEDLLQAWPNFILAMDPDVITGYNIQNFDLPYLISRAQTLKVDRFPFLGRVTGLRSNIRDSSFQSRQVGRRDSKVVSMVGRVQMDMLQVLLREHKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNEQTRRRLAVYCLRDAFLPLRLLERLMVLVNNVEMARVTGVPLGYLLSRGQQVKVVSQLLRQAMRQGLLMPVVKTEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPG-AAQKLGLKPDEFIKTPTGDEFVKSSVRKGLLPQILENLLSARKRAKAELAQETDPLRRQVLDGRQLALKVSANSVYGFTGAEVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTLENGYNANAKVVYGDTDSVMCRFGVSSVAEAMSLGREAANWVSSHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSQPDTHDRMDCKGLEAVRRDNCPLVANLVTSSLRRILVDRDPDGAVAHAKDVISDLLCNRIDISQLVITKELTRAAADYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIIGAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLGQQLAKPLLRIFEPILGEGRAESVLLRGDHTRCKTVLTSKVGGLLAFTKRRNCCIGCRSVI-NHQGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQERLLQRFG 1096 HSP 2 Score: 71.2478 bits (173), Expect = 5.752e-11 Identity = 38/121 (31.40%), Postives = 59/121 (48.76%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY-----EIKETNPRS-----VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLK--QRASQHQYAENLICKVEYCLKAS 547
+W R + + P PLIFQQL+ID+Y + P S + R +G G S+ H+HGF PY Y PPGF EH + ++ L+ + QR + + + + +E C + S
Sbjct: 74 RWKRPALCALDPNTEPLIFQQLEIDHYVGSAVPLPGGPPTSCNSVPILRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGAEHLSDLQRELSTAISRDQRGGK-ELSGPAVLAIELCSRES 193
BLAST of DNA polymerase vs. UniProt/SwissProt
Match: sp|P52431|DPOD1_MOUSE (DNA polymerase delta catalytic subunit OS=Mus musculus OX=10090 GN=Pold1 PE=1 SV=2) HSP 1 Score: 1121.3 bits (2899), Expect = 0.000e+0 Identity = 527/906 (58.17%), Postives = 695/906 (76.71%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++G+ + FL++T+ +P L+A +R+L +G+ +P G + A ++ ++DF +RFMVD+ + GC+W+ELP Y VR +K + CQLEVDV W +I H E +W IAP+R+LSFDIECAGRKG FP+ + DPVIQI ++ +R+GE EPF++ TL CAPI+GA V ++ E +LL+ W++FI +DPD+ITGYN QNFDLPYLI+RA L V F LGR+ +RS I +S QS+Q+GRR +K + M GR+ D+ +LLR+HKLRSY+LNAVSFHFL EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRL+ +LMV+VN VEMARVTGVPL YLL+RGQQ+KV+SQLLR+A + ++P +++ +++TGATVIEP+KG+YD PIATLDF+SLYPSIMMAHNLCYTTLL+ + ++ GL D++IKTP G FVKSSV+KGLLP IL L+ ARK+AK ELA ETDP +RQVLDGRQLALK+SANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + NGY +AKV+YGDTDSVMC FGVS+V EAM+LG+EAA +S F +PI+LEFEKVY+PYLLISKKRYAG+ + ++ D+ DKMDCKG+E VRRDNCPLVANL+ + LR++L+ RD + A++HA+ VI+DLLCNRIDISQL+I+KELT+ +Y KQ H ELA++++KRDPGSAP LGDRVPYVI Y K+EDP++VL++++ IDT YYL+ QL PLLRIFEPI G+ A LL G+H K S VG L +T + CIGC++V+ D + ++C C+P E +Y +E + +LE RFSRLWT+CQRC GSLH++V+C++RDCPIFY RKKV+K+L Q+ +++R
Sbjct: 196 MFGYHGHGPSPFLRITLALPRLMAPARRLLEQGVRVPGLGTPSFAPYEANVDFEIRFMVDADIVGCNWLELPAGKY-VRRAEKKATLCQLEVDVLWSDVISHPPEGQWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEREEDLLQAWADFILAMDPDVITGYNIQNFDLPYLISRAQALKVDRFPFLGRVTGLRSNIRDSSFQSRQVGRRDSKVISMVGRVQMDMLQVLLREHKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAFLPLRLLERLMVLVNNVEMARVTGVPLGYLLTRGQQVKVVSQLLRQAMRQGLLMPVVKTEGSEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPG-AAQKLGLKPDEFIKTPTGDEFVKSSVRKGLLPQILENLLSARKRAKAELAQETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYDANAKVVYGDTDSVMCRFGVSSVAEAMSLGREAANWVSSHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRSDAHDKMDCKGLEAVRRDNCPLVANLVTSSLRRILVDRDPDGAVAHAKDVISDLLCNRIDISQLVITKELTRAAADYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIIGAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAESVLLRGDHTRCKTVLTSKVGGLLAFTKRRNCCIGCRSVI-DHQGAVCKFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQERLLQRFG 1098 HSP 2 Score: 73.559 bits (179), Expect = 9.449e-12 Identity = 38/121 (31.40%), Postives = 57/121 (47.11%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY----------EIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLK--QRASQHQYAENLICKVEYCLKAS 547
+W R + + P PLIFQQL+ID+Y + N + R +G G S+ H+ GF PY Y PPGF EH E ++ LN + QR + + + + +E C + S
Sbjct: 76 RWRRPTLRALDPSTEPLIFQQLEIDHYVGSAPPLPEGPLPSRNSVPILRAFGVTDEGFSVCCHIQGFAPYFYTPAPPGFGAEHLSELQQELNAAISRDQRGGK-ELSGPAVLAIELCSRES 195
BLAST of DNA polymerase vs. TrEMBL
Match: K1PLY1 (DNA polymerase OS=Crassostrea gigas OX=29159 GN=CGI_10007383 PE=3 SV=1) HSP 1 Score: 1216.45 bits (3146), Expect = 0.000e+0 Identity = 583/911 (64.00%), Postives = 714/911 (78.38%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVR--FMVDSGLDGCSWIELPINTYTVR----PQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
IYG+ N K FLK+TV +P L+A KR+L +G T P Y + +++++IDF VR FMVD+ + GCSWIE+P Y +R P+ S CQ+EVDV W+ I H E EW ++AP RILS+DIECAGRKG FP+ D DPVIQI+N+++R GE +PFI+N+FTL +CAP+VG+ VI ++ E++LL+ W+ F+R +DPDIITGYN QNFD PY+INRAN L V F+ LGR + +RS I ES QSKQMG+R NK +++ GR+ FDL ILLRD+KLRSY+LNAVSFHFL+EQKEDV H IITDLQNG+D+TR RLAVYCLKD+ L LRL++KLM V+NY+EMARVTGVPL YLLSRGQQ+KV+SQLLRKA +D VLP ++ + GDE+ GATVIEP+KGFYD PIATLDF+SLYPSIMMAHNLCYTTLL S+ SI++ GLT D YIKTP G+YF+K+ +KGLLP IL L+ ARKKAK +L ETDPFK++VLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVTAFGR MI+ TK VE + ANGY HDAKVIYGDTDSVMC FGV TV EAM LG+EAA IS KFI PIKLEFEKVY+PYLLI+KKRYAG+Y+T P+ DKMDCKG+ETVRRDN PLVANL+NTCL+ +LI+RD A+ +A+ I+DLLCNRIDISQL+I+KELTKT +EY KQ H ELA ++KKRDPGSAPQLGDRVPYVI Y +EDPIYVL+NNI IDT YYL+NQL+ PLLRIFEPI G++ A +LL G+H +K K S VG L + K CIGC+ VL++D ++C +CKP E IY +E + LE +FSRLWT+CQRC GSLH++VLC++RDCPIFY RKKVQK+L QD+++ R
Sbjct: 177 IYGYHGNKKIPFLKITVAIPRLIAPAKRLLEQGFTCPGYSSNGFQAYESNIDFEVRQEFMVDTDVVGCSWIEIPAGKYRIRTKDDPKFPVKSRCQMEVDVSWEDFISHVPEGEWSAMAPFRILSYDIECAGRKGVFPEPDKDPVIQIANMVIRQGERDPFIRNVFTLRSCAPVVGSQVISNEKESDLLKKWAEFVRVVDPDIITGYNIQNFDFPYVINRANHLKVMDFTFLGRQRDVRSVIKESMFQSKQMGKRENKVINIEGRVQFDLLQILLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAILPLRLLDKLMCVINYMEMARVTGVPLPYLLSRGQQVKVVSQLLRKAKEQDLVLPTHKVETGDEYEGATVIEPVKGFYDSPIATLDFSSLYPSIMMAHNLCYTTLL-SQHSIQKEGLTPDQYIKTPSGNYFIKTQHRKGLLPEILEHLLSARKKAKADLKKETDPFKKKVLDGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTAFGRMMIEQTKTYVEEHYTIANGYQHDAKVIYGDTDSVMCKFGVGTVAEAMKLGQEAADLISEKFIKPIKLEFEKVYFPYLLINKKRYAGLYWTNPEKHDKMDCKGIETVRRDNSPLVANLINTCLQLILINRDPQGAVEYAKQAISDLLCNRIDISQLVITKELTKTGDEYAGKQAHVELAHRMKKRDPGSAPQLGDRVPYVIIAGTKGSAAYMNSEDPIYVLENNIAIDTQYYLENQLSKPLLRIFEPILGEKKAESELLRGDHTRTKTKVASKVGGLMAFAKKKATCIGCRTVLQEDGIAVCKYCKPKESEIYQKEISHLNILEEKFSRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLADQDKLLHRFG 1086 HSP 2 Score: 86.2705 bits (212), Expect = 3.528e-13 Identity = 58/179 (32.40%), Postives = 89/179 (49.72%), Query Frame = 2
Query: 65 KTYAPSSKISKFEVKNNDEDDVS-MDEWNHEPEEICFEMESNTETVKETDEFS--------KWARQNMDVVKPEIMPLIFQQLDIDNYEIKET--------NPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLK-QRASQHQYAENLICKVEYCLKAS 547
K P +K +F NDED+ S ++ +EI EM+ N + T +S KW R + +K + LIFQQ+D+D+Y + P V R YG NGNS++AH+HGF PY +V GF +EHC +FRK L+ ++ S + + + V++ +K S
Sbjct: 2 KKGGPPNKKPRF----NDEDEPSHFEDELALLDEIEMEMQDNFDEPDGTAGYSPEDVNAPTKWCRPPLPKMKADKDKLIFQQIDVDHYIGRHLPGMPGATQGPVPVIRMYGVTLNGNSVLAHIHGFAPYFFVPAQQGFKREHCEQFRKHLDSVVRGDLRSNREEIQTAVLAVDFVMKES 176
BLAST of DNA polymerase vs. TrEMBL
Match: R7TGI4 (DNA polymerase OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_165849 PE=3 SV=1) HSP 1 Score: 1216.45 bits (3146), Expect = 0.000e+0 Identity = 570/905 (62.98%), Postives = 708/905 (78.23%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
IYG+ N K +LK+T+ +P L+A KR+L +G Y HN A ++++IDF +RFMVD+ + GC+WI LP Y VRP+ + CQ+E DV WD+ + H E +W +AP+ LSFDIECAGRKG FP+ D DPVIQI+N+++R GE EPFI+N+FTL CAPIVGA V+ ++EAELL+ W+ FIRE+DPD+ITGYN QNFDLPYL+NRA L VK F LGRIK ++S + E+ QSKQMG+R NK ++M GR+ FDL +LLRD+KLRSY+LNAVSFHFLEEQKEDV H II+DLQNG D+TR RLAVYCLKD+ L LRL++KLM ++NY+EMARVTGV L LLSRGQQIKV+SQLLRKA +D V+P Y+ + GDEFTGATVIEP++G+YD P+ATLDFASLYPSIMMAHNLCYTTL+ + SI + GL+ D YIKTP S FVKS+V+KGLLP IL L+ ARKKAK EL ETDPF+++VLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVTAFGR MI+ TK+ VE ++ NGY HDA V+YGDTDSVMC FGVSTV EAM LG+EAA I+ F++PIKLEFEKVY+PYLLI+KKRYAG+Y+TK D DKMDCKG+ETVRRDNC LVANL+NTCL+K+LI+RD A+ +A+ I+DLLCNRIDISQL+I+KEL KT++EY +KQ H ELA +++KRD GSAPQLGDRVPYVI K Y K+EDPIYVL+NNI ID YYL+NQL PLLRIFEPI G++ A LL GEH L++ S +G LS +T + CIGCK L ++C HC +E A+Y +E +LE +FSRLWT+CQRC+GSLH+++LC++RDCPIFY RKKVQK+L Q+++++R
Sbjct: 144 IYGYHGNTKSPYLKITMALPKLIAPAKRLLEQGFQFSEYPIHNYAGYESNIDFEIRFMVDTDVVGCNWIVLPAGQYRVRPRNNMKTRCQIESDVAWDQFVSHGPEGDWLKLAPMLTLSFDIECAGRKGIFPEPDKDPVIQIANMVIRQGEKEPFIRNVFTLKACAPIVGAQVLSFESEAELLKKWAEFIREVDPDVITGYNIQNFDLPYLLNRAAHLKVKNFDYLGRIKDIKSTVKEAMVQSKQMGKRENKIINMEGRVIFDLLQVLLRDYKLRSYTLNAVSFHFLEEQKEDVHHSIISDLQNGSDQTRRRLAVYCLKDAYLPLRLLDKLMSIINYIEMARVTGVSLGILLSRGQQIKVMSQLLRKAKTQDLVIPVYKVETGDEFTGATVIEPVRGYYDTPVATLDFASLYPSIMMAHNLCYTTLITTPSSIEKEGLSSDQYIKTPANSLFVKSTVRKGLLPEILESLLSARKKAKTELKSETDPFRKKVLDGRQLALKISANSVYGFTGAQVGKLPCLEISGSVTAFGRLMIEQTKQFVEETYTVKNGYKHDAMVVYGDTDSVMCRFGVSTVAEAMELGQEAALEITKTFVSPIKLEFEKVYFPYLLINKKRYAGLYFTKADVHDKMDCKGIETVRRDNCQLVANLINTCLQKILINRDPMGAVDYAKQTISDLLCNRIDISQLVITKELAKTEDEYAAKQAHVELAHRMRKRDAGSAPQLGDRVPYVIIAAPKKTAAYLKSEDPIYVLENNIPIDVQYYLENQLAKPLLRIFEPILGEKKAESVLLRGEHTLTRTVVTSKIGGLSAFTKKRETCIGCKTPLDKAGVAVCKHCAASESALYQKEICELSALETKFSRLWTQCQRCTGSLHEDILCTSRDCPIFYMRKKVQKDLGHQEKVIQRFG 1048 HSP 2 Score: 73.9442 bits (180), Expect = 2.111e-9 Identity = 40/118 (33.90%), Postives = 61/118 (51.69%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY--EIKETNPRS------VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQ-TLKQRASQHQYAENLICKVEYCLKAS 547
KW+R + + P L+FQQLD+D Y + P S + R +G +G+S++ H+HG+ PY YV F EHCG+FR LN+ +K S + + V+Y +K S
Sbjct: 26 KWSRPLVTPLDPLKESLVFQQLDLDFYIGDPMSGMPGSKSGKVPIVRMFGITASGHSVVTHIHGYLPYFYVLAISNFKPEHCGKFRDALNKVVIKDMRSNKDNVSDAVLAVDYVMKES 143
BLAST of DNA polymerase vs. TrEMBL
Match: A0A267EYR0 (DNA polymerase (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027421g6 PE=3 SV=1) HSP 1 Score: 1215.68 bits (3144), Expect = 0.000e+0 Identity = 582/917 (63.47%), Postives = 711/917 (77.54%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMT-IPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKI---SFCQLEVDV-QWDKIICHSTEE-WPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEK--SICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQDLSW 3455
IYGF +N K+ FL+VTV + L+A KR+L +G + + G H + ++ +IDF +RFMVD+GL GC W+ELP YT+R + ++ S CQLE DV W ++ H E W +AP+RILSFDIECAGR+G FP+ + DPVIQI+N++VR GE++PFI+N+FTL TCA IVG+ V+ KTE++LL WS F+R++DPD+ITGYN QNFD+PYL+ RA L V+ F LGRI + +S I E+Q QSKQMGRR NK V+M GR+ DL IL RD+KLRSYSLNAVS+HFL EQKEDV H IIT+LQNG+++TR RLAVYCLKD+ L LRLM+KLM +VNY+EMARVTGVPL++LLSRGQQ+KV+SQLLRKA +D +LP + + GDE+TGATVIEP+KG+Y PIATLDF+SLYPSIMMAHNLCYTTLL + SI ++ L D+YIKTPCGSYF K +V+KGLLP IL QL+ ARK+AK +L ETD FK++VLDGRQLALKISANSVYGFTGAQ G+LPCL+ISSSVTAFGR MI TK VE + ANGY HDAKVIYGDTDSVMC F +TV +AM LG+EAA IS KF PIKLEFEKVY PYLLI+KKRYAG+Y+TKPD DKMDCKG+ETVRRDN PLVANL+N CL K+LI RD + A+ HA+SVI+DLLCNR+DISQL+ISKELTKTD+EY KQ H ELA KI+KRDPGSAPQLGDRVPYVI + Y KAEDPIYVL+NN+ IDT+YYL+NQL NPLLRIFEPI G A LL GEH K S VG L+ + + C+GCK VL D ++C HC+PNE A+Y RE + LE +F+RLWTECQRC GSLH++VLC++RDCPIFY RK++QK+L QD ++ R + W
Sbjct: 222 IYGFHRNRKQPFLRVTVALQRLMAPAKRLLEQGFSWLQGRGSHCFSLYEANIDFEIRFMVDTGLVGCCWVELPAGKYTLREKENRLAPQSRCQLEADVASWSDVVAHPAEGVWSKVAPLRILSFDIECAGRRGVFPEPERDPVIQIANMVVRHGETDPFIRNVFTLGTCASIVGSQVLSFKTESDLLAAWSAFVRDVDPDVITGYNIQNFDMPYLLKRAATLKVQQFPFLGRISATKSTIREAQIQSKQMGRRENKWVNMEGRVQLDLLQILFRDYKLRSYSLNAVSYHFLHEQKEDVQHSIITELQNGNEQTRRRLAVYCLKDAYLPLRLMDKLMCLVNYMEMARVTGVPLTFLLSRGQQVKVISQLLRKAKEQDLLLPTQKVEQGDEYTGATVIEPVKGYYTTPIATLDFSSLYPSIMMAHNLCYTTLL-DQASIAKYSLQPDEYIKTPCGSYFAKKNVRKGLLPEILEQLLNARKRAKDDLKNETDEFKKRVLDGRQLALKISANSVYGFTGAQVGKLPCLDISSSVTAFGRTMIMETKRYVEERYTVANGYAHDAKVIYGDTDSVMCRFNAATVADAMKLGREAADYISSKFPPPIKLEFEKVYCPYLLINKKRYAGLYFTKPDKHDKMDCKGIETVRRDNSPLVANLVNACLHKILIDRDPDGAVQHAKSVISDLLCNRVDISQLVISKELTKTDDEYAGKQAHVELANKIRKRDPGSAPQLGDRVPYVIVSAAKGTPAYQKAEDPIYVLENNVPIDTNYYLENQLANPLLRIFEPILGDGKARSMLLSGEHTRVKAVVHSKVGGLAAFATRRAACLGCKAVLPQDAANGAVCKHCEPNESALYQREVGVLRVLEEKFNRLWTECQRCQGSLHEDVLCTSRDCPIFYMRKRLQKDLADQDALVGRFGEPYDW 1137 HSP 2 Score: 73.559 bits (179), Expect = 3.326e-9 Identity = 35/90 (38.89%), Postives = 48/90 (53.33%), Query Frame = 2
Query: 221 KWARQNM-DVVKPEIMPLIFQQLDIDNYEIKETNPRS----VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTL 475
KW R + P PL+FQQ+D+D Y + S V R YG + G+S++ HVHGF PY +V P GF C F++ LNQ +
Sbjct: 107 KWRRAPLPHAADPATQPLVFQQMDLDCYTLPAAGSGSGASPVVRMYGITEAGHSVLVHVHGFNPYFFVPAPEGFSPADCHSFKQALNQAV 196
BLAST of DNA polymerase vs. TrEMBL
Match: A0A293LKP1 (DNA polymerase (Fragment) OS=Ornithodoros erraticus OX=265619 PE=3 SV=1) HSP 1 Score: 1215.68 bits (3144), Expect = 0.000e+0 Identity = 579/917 (63.14%), Postives = 710/917 (77.43%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEG-MTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQ------TEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQDLSW 3455
IYG+S K+ FLKVT+ +P L+A KR+L G ++IP G + +++++DF +R+MVDSG+ GCSWIELP TY +R K+S CQ+EVDV WD ++ H+ E +W +AP RILSFDIECAGRKG FP+AD D VIQI+N++VR G +PFI+N+FTLNTCAPI G V+ K E ELL+ W++FIRE+DPDI+TGYN QNFD PYLINRA L+V F LGRI+ R+ + +S QSKQMGRR NK + M GR+ FDL L L+RD+KLRSY+LNAVS+HFL+EQKEDV H IITDLQNG D+TR RLAVYCLKD+ L LRL++KLM ++NY+EMARVTGVPL+YLL+RGQQIKV+SQLLRKAA +D V+P + GD++TGATVIEP+KGFY PI TLDF+SLYPSIMMAHNLCYTTLL + + L DD+I+TP G YFVKS ++KGLLP IL L+ ARKKAK +L ETDPF+++VLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVTAFGR MI+ TK VE + KANGY D+KVIYGDTDSVM FGV T+ EAM LGKEAA+ ++ KFI PI LEFEKVY+PYLLI+KKRYAG+ YT+PD++DKMDCKG+ETVRRDNCPLVANL+NTCL K+LI D NAA+ A+ IADLLCNR+DISQL+I+KELTK D EY +KQ H ELA +++KRDPGSAP LGDRVPYVI Y K+EDPIYVL NNI IDT YYL+NQL+ PLLR+FEPI G+ A LL G+H +K S VGAL+ +T + CIGC+ VL D+ ++CAHCKP E IY E ++ SLE +F++LWT+CQRCSGSLH+EVLC++RDCPIFY R KVQK+L QD+++ R SW
Sbjct: 188 IYGYSDKGKQPFLKVTMVLPRLIAPAKRLLENGAISIPVCGPVSYKIYESNVDFEIRYMVDSGVVGCSWIELPAGTYRLRSSGGEDGTKRKVSRCQMEVDVAWDALVAHAPEGQWARVAPFRILSFDIECAGRKGIFPEADKDSVIQIANMVVRQGSKDPFIRNVFTLNTCAPIAGCEVLSFKREQELLQKWADFIREVDPDIVTGYNIQNFDFPYLINRAKHLSVSQFPFLGRIRDSRTLVKDSVLQSKQMGRRENKIITMEGRVQFDLLLALVRDYKLRSYTLNAVSYHFLQEQKEDVQHSIITDLQNGTDQTRRRLAVYCLKDAMLPLRLLDKLMCIINYMEMARVTGVPLTYLLTRGQQIKVVSQLLRKAAEQDLVMPTVHQETGDDYTGATVIEPVKGFYSVPITTLDFSSLYPSIMMAHNLCYTTLLDPRHKDK---LAADDFIRTPSGDYFVKSKLRKGLLPEILEDLLSARKKAKADLKKETDPFRKKVLDGRQLALKISANSVYGFTGAQVGKLPCLPISQSVTAFGRMMIEQTKREVEEKYTKANGYPADSKVIYGDTDSVMIRFGVDTLTEAMRLGKEAAEYVTSKFIRPINLEFEKVYFPYLLINKKRYAGLLYTRPDTYDKMDCKGIETVRRDNCPLVANLINTCLEKILIENDPNAAIDFAKQTIADLLCNRVDISQLVITKELTKNDGEYAAKQAHVELANRMRKRDPGSAPNLGDRVPYVIIAAAKGTAAYLKSEDPIYVLKNNIPIDTQYYLENQLSKPLLRVFEPILGETRAESVLLRGDHTRTKTVVHSKVGALAAFTKKRSTCIGCRAVLDDESAAVCAHCKPREAEIYLVEVQHQNSLETKFAKLWTQCQRCSGSLHEEVLCTSRDCPIFYMRMKVQKDLTDQDKVVSRFGAP-SW 1100 HSP 2 Score: 81.2629 bits (199), Expect = 1.500e-11 Identity = 52/150 (34.67%), Postives = 77/150 (51.33%), Query Frame = 2
Query: 77 PSSKISKFEVKNNDED--DVSMDEWNHE---PEEICFEMESNTETV----KETDEFSKWARQNMDVVKPEIMPLIFQQLDIDNYEIK--------ETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTL 475
PS KF +++D++ D M+ + E EE ++ ES E+V ++T ++WAR +KP L FQQLD+D+Y + T + R +G G+S++ HVHGF PY YVE P F KEHC F+ LN +
Sbjct: 14 PSQGNKKFRSQDDDDEPMDFEMELASMEDMMSEEQTYDTESQ-ESVGQGPEDTCTSARWARPPAPRLKPSSQSLEFQQLDLDHYLGQPMDGMPGMRTGTVPIVRMFGVTDGGHSVLCHVHGFLPYFYVEAPNNFRKEHCRAFKDALNTAV 162
BLAST of DNA polymerase vs. TrEMBL
Match: A0A267EYT1 (DNA polymerase (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027421g2 PE=3 SV=1) HSP 1 Score: 1214.91 bits (3142), Expect = 0.000e+0 Identity = 582/917 (63.47%), Postives = 710/917 (77.43%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPH-YGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKI---SFCQLEVDV-QWDKIICHSTEE-WPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEK--SICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQDLSW 3455
IYGF +N K+ FL+VTV + L+A KR+L +G + G H + ++ +IDF +RFMVD+GL GC W+ELP YT+R + ++ S CQLE DV W ++ H E W +AP+RILSFDIECAGR+G FP+ + DPVIQI+N++VR GE++PFI+N+FTL TCA IVG+ V+ KTE++LL WS F+R++DPD+ITGYN QNFD+PYL+ RA L V+ F LGRI + +S I E+Q QSKQMGRR NK V+M GR+ DL IL RD+KLRSYSLNAVS+HFL EQKEDV H IIT+LQNG+++TR RLAVYCLKD+ L LRLM+KLM +VNY+EMARVTGVPL++LLSRGQQ+KV+SQLLRKA +D +LP + + GDE+TGATVIEP+KG+Y PIATLDF+SLYPSIMMAHNLCYTTLL + SI ++ L D+YIKTPCGSYF K +V+KGLLP IL QL+ ARK+AK +L ETD FK++VLDGRQLALKISANSVYGFTGAQ G+LPCL+ISSSVTAFGR MI TK VE + ANGY HDAKVIYGDTDSVMC F +TV +AM LG+EAA IS KF PIKLEFEKVY PYLLI+KKRYAG+Y+TKPD DKMDCKG+ETVRRDN PLVANL+N CL K+LI RD + A+ HA+SVI+DLLCNR+DISQL+ISKELTKTD+EY KQ H ELA KI+KRDPGSAPQLGDRVPYVI + Y KAEDPIYVL+NN+ IDT+YYL+NQL NPLLRIFEPI G A LL GEH K S VG L+ + + C+GCK VL D ++C HC+PNE A+Y RE + LE +F+RLWTECQRC GSLH++VLC++RDCPIFY RK++QK+L QD ++ R + W
Sbjct: 220 IYGFHRNRKQPFLRVTVALQRLMAPAKRLLEQGFSWQQGRGSHCFSLYEANIDFEIRFMVDTGLVGCCWVELPAGKYTLREKENRLAPQSRCQLEADVASWSDVVAHPAEGVWSKVAPLRILSFDIECAGRRGVFPEPERDPVIQIANMVVRHGETDPFIRNVFTLGTCASIVGSQVLSFKTESDLLAAWSAFVRDVDPDVITGYNIQNFDMPYLLKRAATLKVQQFPFLGRISATKSTIREAQIQSKQMGRRENKWVNMEGRVQLDLLQILFRDYKLRSYSLNAVSYHFLHEQKEDVQHSIITELQNGNEQTRRRLAVYCLKDAYLPLRLMDKLMCLVNYMEMARVTGVPLTFLLSRGQQVKVISQLLRKAKEQDLLLPTQKVEQGDEYTGATVIEPVKGYYTTPIATLDFSSLYPSIMMAHNLCYTTLL-DQASIAKYSLQPDEYIKTPCGSYFAKKNVRKGLLPEILEQLLNARKRAKDDLKNETDEFKKRVLDGRQLALKISANSVYGFTGAQVGKLPCLDISSSVTAFGRTMIMETKRYVEERYTVANGYAHDAKVIYGDTDSVMCRFNAATVADAMKLGREAADYISSKFPPPIKLEFEKVYCPYLLINKKRYAGLYFTKPDKHDKMDCKGIETVRRDNSPLVANLVNACLHKILIDRDPDGAVQHAKSVISDLLCNRVDISQLVISKELTKTDDEYAGKQAHVELANKIRKRDPGSAPQLGDRVPYVIVSAAKGTPAYQKAEDPIYVLENNVPIDTNYYLENQLANPLLRIFEPILGDGKARSMLLSGEHTRVKAVVHSKVGGLAAFATRRAACLGCKAVLPQDAANGAVCKHCEPNESALYQREVGVLRVLEEKFNRLWTECQRCQGSLHEDVLCTSRDCPIFYMRKRLQKDLADQDALVGRFGEPCDW 1135 HSP 2 Score: 72.7886 bits (177), Expect = 4.627e-9 Identity = 35/90 (38.89%), Postives = 48/90 (53.33%), Query Frame = 2
Query: 221 KWARQNM-DVVKPEIMPLIFQQLDIDNYEIKETNPRS----VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTL 475
KW R + P PL+FQQ+D+D Y + S V R YG + G+S++ HVHGF PY +V P GF C F++ LNQ +
Sbjct: 105 KWRRAPLPHAADPATQPLMFQQMDLDCYTLPAAGSGSGASPVVRMYGITEAGHSVLVHVHGFNPYFFVPAPEGFSPADCHSFKQALNQAV 194
BLAST of DNA polymerase vs. Ensembl Cavefish
Match: pold1 (DNA polymerase delta 1, catalytic subunit [Source:NCBI gene;Acc:103023852]) HSP 1 Score: 1151.73 bits (2978), Expect = 0.000e+0 Identity = 548/917 (59.76%), Postives = 700/917 (76.34%), Query Frame = 3
Query: 726 DIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTE----------KISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++YG+ + FL++T+ +P LVA KR+L +G ++ + + ++ +IDF +RFMVD + GC WIELP Y +R + K+S CQ EVDV W+ +I H E EW IAP+R+LSFDIECAGRKG FP+A++DPVIQI++++ R GE EPFI+ +FTL +CA IVG+ ++ E +LL+ W+ F+R +DPDIITGYN QNFDLPYL+NRA L V F LGR++ ++S + +S QSKQMGRR NK V+M GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRL+ KLM V+NY+EMARVTGVPL+YLLSRGQQIKV+SQLLR+A +D V+P +++ G+++TGATVIEP KG+Y PIATLDF+SLYPSIMMAHNLCYTTLL+ ++ + GL+ +D+I+TP G FVKSSV+KGLLP IL L+ ARK+AK EL ETDPFK+QVLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + ANGY DAKV+YGDTDSVM GV TV EAM +G+EAA+ +S F+ PIKLEFEKVY+PYLLI+KKRYAG+Y+ + + DKMDCKG+ETVRRDNCPLVANL+NTCL+K+LI RD + A++HA+ VI+DLLCNRIDISQL+I+KELT+T +EY +Q H ELA++++KRD GSAP LGDRVPYVI Y K+EDPIYVL+NNI IDT YYL+ QL+ PL+RIFEPI G+ A LL G+H K S VG L + + CIGC+ VL+ D ++C CK E +Y +E + +LE +FSRLWT+CQRC GSLH++VLC++RDCPIFY RKKVQK+L Q +++ R
Sbjct: 190 NMYGYHGSRPLDFLRITMAMPRLVAPAKRLLEQGFKFANFSTQSYSPYEANIDFEIRFMVDCDVVGCCWIELPKGKYKLREERTTKDTDSRHPGKVSLCQYEVDVGWNDLISHPAEGEWQRIAPLRVLSFDIECAGRKGVFPEAEVDPVIQIASMVQRQGEKEPFIRTVFTLQSCASIVGSQILCFTQEKQLLQSWAEFVRTVDPDIITGYNIQNFDLPYLLNRAAALKVNLFPYLGRVRGIKSILKDSSFQSKQMGRRENKTVNMEGRVQFDLLQVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAYLPLRLLQKLMCVINYMEMARVTGVPLTYLLSRGQQIKVVSQLLRQAMKQDLVMPVVKTEGGEDYTGATVIEPEKGYYSIPIATLDFSSLYPSIMMAHNLCYTTLLQKGQADK-LGLSAEDFIRTPTGDLFVKSSVRKGLLPEILENLLSARKRAKAELKKETDPFKKQVLDGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEQTKQLVESKYTIANGYKADAKVVYGDTDSVMVKLGVDTVQEAMTVGREAAEWVSSHFVPPIKLEFEKVYHPYLLINKKRYAGLYFSSSAEHHDKMDCKGIETVRRDNCPLVANLINTCLQKILIDRDPDGAVAHAKEVISDLLCNRIDISQLVITKELTRTAQEYAGRQAHVELAERMRKRDAGSAPNLGDRVPYVIIKAAKGVAAYMKSEDPIYVLENNIPIDTQYYLEQQLSKPLMRIFEPILGESKAESVLLKGDHTRCKTVLTSRVGGLMAFAQKRSTCIGCRAVLKTD-AAVCDFCKKKESELYQKEIAHLSALEEKFSRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLDDQGKLVSRFG 1104 HSP 2 Score: 76.6406 bits (187), Expect = 1.338e-13 Identity = 49/139 (35.25%), Postives = 66/139 (47.48%), Query Frame = 2
Query: 137 DEWNHEPEEICF--EMESNTET---------VKETDEFS-----KWARQNMDVVKPEIMPLIFQQLDIDNY----------EIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTL 475
D +H EE+ EME + E+ + D FS +W R +KP+ LIFQQ+D+D Y +++ P V R +G NGNS+ HVHGF PY YV P GF H EF+K LN +
Sbjct: 29 DGPSHFEEELALFDEMEMDAESGEGQAGHDVIPVGDLFSADLNPRWRRPTAPTIKPDKDTLIFQQIDLDYYLGSAVAGMPGQVQGKVP--VVRMFGVTDNGNSVCCHVHGFAPYFYVPAPAGFTAAHLSEFQKELNSAV 165
BLAST of DNA polymerase vs. Ensembl Cavefish
Match: pold1 (DNA polymerase delta 1, catalytic subunit [Source:NCBI gene;Acc:103023852]) HSP 1 Score: 1151.73 bits (2978), Expect = 0.000e+0 Identity = 548/917 (59.76%), Postives = 700/917 (76.34%), Query Frame = 3
Query: 726 DIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTE----------KISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++YG+ + FL++T+ +P LVA KR+L +G ++ + + ++ +IDF +RFMVD + GC WIELP Y +R + K+S CQ EVDV W+ +I H E EW IAP+R+LSFDIECAGRKG FP+A++DPVIQI++++ R GE EPFI+ +FTL +CA IVG+ ++ E +LL+ W+ F+R +DPDIITGYN QNFDLPYL+NRA L V F LGR++ ++S + +S QSKQMGRR NK V+M GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRL+ KLM V+NY+EMARVTGVPL+YLLSRGQQIKV+SQLLR+A +D V+P +++ G+++TGATVIEP KG+Y PIATLDF+SLYPSIMMAHNLCYTTLL+ ++ + GL+ +D+I+TP G FVKSSV+KGLLP IL L+ ARK+AK EL ETDPFK+QVLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + ANGY DAKV+YGDTDSVM GV TV EAM +G+EAA+ +S F+ PIKLEFEKVY+PYLLI+KKRYAG+Y+ + + DKMDCKG+ETVRRDNCPLVANL+NTCL+K+LI RD + A++HA+ VI+DLLCNRIDISQL+I+KELT+T +EY +Q H ELA++++KRD GSAP LGDRVPYVI Y K+EDPIYVL+NNI IDT YYL+ QL+ PL+RIFEPI G+ A LL G+H K S VG L + + CIGC+ VL+ D ++C CK E +Y +E + +LE +FSRLWT+CQRC GSLH++VLC++RDCPIFY RKKVQK+L Q +++ R
Sbjct: 207 NMYGYHGSRPLDFLRITMAMPRLVAPAKRLLEQGFKFANFSTQSYSPYEANIDFEIRFMVDCDVVGCCWIELPKGKYKLREERTTKDTDSRHPGKVSLCQYEVDVGWNDLISHPAEGEWQRIAPLRVLSFDIECAGRKGVFPEAEVDPVIQIASMVQRQGEKEPFIRTVFTLQSCASIVGSQILCFTQEKQLLQSWAEFVRTVDPDIITGYNIQNFDLPYLLNRAAALKVNLFPYLGRVRGIKSILKDSSFQSKQMGRRENKTVNMEGRVQFDLLQVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAYLPLRLLQKLMCVINYMEMARVTGVPLTYLLSRGQQIKVVSQLLRQAMKQDLVMPVVKTEGGEDYTGATVIEPEKGYYSIPIATLDFSSLYPSIMMAHNLCYTTLLQKGQADK-LGLSAEDFIRTPTGDLFVKSSVRKGLLPEILENLLSARKRAKAELKKETDPFKKQVLDGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEQTKQLVESKYTIANGYKADAKVVYGDTDSVMVKLGVDTVQEAMTVGREAAEWVSSHFVPPIKLEFEKVYHPYLLINKKRYAGLYFSSSAEHHDKMDCKGIETVRRDNCPLVANLINTCLQKILIDRDPDGAVAHAKEVISDLLCNRIDISQLVITKELTRTAQEYAGRQAHVELAERMRKRDAGSAPNLGDRVPYVIIKAAKGVAAYMKSEDPIYVLENNIPIDTQYYLEQQLSKPLMRIFEPILGESKAESVLLKGDHTRCKTVLTSRVGGLMAFAQKRSTCIGCRAVLKTD-AAVCDFCKKKESELYQKEIAHLSALEEKFSRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLDDQGKLVSRFG 1121 HSP 2 Score: 76.6406 bits (187), Expect = 1.216e-13 Identity = 48/136 (35.29%), Postives = 65/136 (47.79%), Query Frame = 2
Query: 146 NHEPEEICF--EMESNTET---------VKETDEFS-----KWARQNMDVVKPEIMPLIFQQLDIDNY----------EIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTL 475
+H EE+ EME + E+ + D FS +W R +KP+ LIFQQ+D+D Y +++ P V R +G NGNS+ HVHGF PY YV P GF H EF+K LN +
Sbjct: 49 SHFEEELALFDEMEMDAESGEGQAGHDVIPVGDLFSADLNPRWRRPTAPTIKPDKDTLIFQQIDLDYYLGSAVAGMPGQVQGKVP--VVRMFGVTDNGNSVCCHVHGFAPYFYVPAPAGFTAAHLSEFQKELNSAV 182
BLAST of DNA polymerase vs. Ensembl Cavefish
Match: pold1 (DNA polymerase delta 1, catalytic subunit [Source:NCBI gene;Acc:103023852]) HSP 1 Score: 1077.39 bits (2785), Expect = 0.000e+0 Identity = 524/919 (57.02%), Postives = 677/919 (73.67%), Query Frame = 3
Query: 726 DIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQ---TEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAE---------DPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++YG+ + FL++T+ +P LVA KR+L +G ++ + + ++ +IDF +RFMVD + GC WIELP Y +R + + S +VDV W+ +I H E EW IAP+R+LSFDIECAGRKG FP+A++DPVIQI++++ R GE EPFI+ +FTL +CA IVG+ ++ E +LL+ W+ F+R +DPDIITGYN QNFDLPYL+NRA L V F LGR++ ++S + +S QSKQMGRR NK V+M GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRL+ KLM V+NY+EMARVTGVPL+YLLSRGQQIKV+SQLLR+A +D V+P +++ G+++TG + +TLDF+SLYPSIMMAHNLCYTTLL+ ++ + GL+ +D+I+TP G FVKSSV+KGLLP IL L+ ARK+AK EL ETDPFK+QVLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + ANGY DAKV+YGDTDSVM GV TV EAM +G+EAA+ +S F+ PIKLEFEKVY+PYLLI+KKRYAG+Y+ + + DKMDCKG+ETVRRDNCPLVANL+NTCL+K+LI RD + A++HA+ VI+DLLCNRIDISQL+I+KELT+T +EY +Q H ELA++++KRD GSAP LGDRVPYVI Y K+E DPIY YYL+ QL+ PL+RIFEPI G+ A LL G+H K S VG L + + CIGC+ VL+ D ++C CK E +Y +E + +LE +FSRLWT+CQRC GSLH++VLC++RDCPIFY RKKVQK+L Q +++ R
Sbjct: 183 NMYGYHGSRPLDFLRITMAMPRLVAPAKRLLEQGFKFANFSTQSYSPYEANIDFEIRFMVDCDVVGCCWIELPKGKYKLREERTTKDTDSRHPGKVDVGWNDLISHPAEGEWQRIAPLRVLSFDIECAGRKGVFPEAEVDPVIQIASMVQRQGEKEPFIRTVFTLQSCASIVGSQILCFTQEKQLLQSWAEFVRTVDPDIITGYNIQNFDLPYLLNRAAALKVNLFPYLGRVRGIKSILKDSSFQSKQMGRRENKTVNMEGRVQFDLLQVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAYLPLRLLQKLMCVINYMEMARVTGVPLTYLLSRGQQIKVVSQLLRQAMKQDLVMPVVKTEGGEDYTGVST---------AVFSTLDFSSLYPSIMMAHNLCYTTLLQKGQADK-LGLSAEDFIRTPTGDLFVKSSVRKGLLPEILENLLSARKRAKAELKKETDPFKKQVLDGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEQTKQLVESKYTIANGYKADAKVVYGDTDSVMVKLGVDTVQEAMTVGREAAEWVSSHFVPPIKLEFEKVYHPYLLINKKRYAGLYFSSSAEHHDKMDCKGIETVRRDNCPLVANLINTCLQKILIDRDPDGAVAHAKEVISDLLCNRIDISQLVITKELTRTAQEYAGRQAHVELAERMRKRDAGSAPNLGDRVPYVIIKAAKGVAAYMKSEVGSVFLYESDPIY-----------YYLEQQLSKPLMRIFEPILGESKAESVLLKGDHTRCKTVLTSRVGGLMAFAQKRSTCIGCRAVLKTD-AAVCDFCKKKESELYQKEIAHLSALEEKFSRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLDDQGKLVSRFG 1079 HSP 2 Score: 78.9518 bits (193), Expect = 2.733e-14 Identity = 46/129 (35.66%), Postives = 64/129 (49.61%), Query Frame = 2
Query: 146 NHEPEEICF----EMESNTETVKETDEFS-----KWARQNMDVVKPEIMPLIFQQLDIDNY----------EIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTL 475
+H EE+ EM++ + + D FS +W R +KP+ LIFQQ+D+D Y +++ P V R +G NGNS+ HVHGF PY YV P GF H EF+K LN +
Sbjct: 32 SHFEEELALFDEMEMDAESGEGQAGDLFSADLNPRWRRPTAPTIKPDKDTLIFQQIDLDYYLGSAVAGMPGQVQGKVP--VVRMFGVTDNGNSVCCHVHGFAPYFYVPAPAGFTAAHLSEFQKELNSAV 158
BLAST of DNA polymerase vs. Ensembl Cavefish
Match: rev3l (REV3 like, DNA directed polymerase zeta catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-050302-55]) HSP 1 Score: 304.294 bits (778), Expect = 2.455e-84 Identity = 245/851 (28.79%), Postives = 402/851 (47.24%), Query Frame = 3
Query: 1065 IRILSFDIECAGRKGSFPDADIDPVIQI-----SNIIVRFGESEPFI---------KNIFTLNT--CAP------IVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDL-------VLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDF--VLPDYQSKDGDEFTGAT--VIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIR-----EFGLTE------------DDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKREL-AIETDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKM-DCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQ--PHSELAQKIKKRDPGSAPQLGDRVPYVIT--TLGVKDKIYTKAEDPIYVL-DNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQ 3443
+ +++ ++ R+ PD + DP+ + S+ + +S F K +FT ++ AP + G V E EL E N +R DPDI+ GY Q YL+ RA+ L V L R+ +K + + G +H+ GRI +L+ I+ + L +YS V+FH L ++ + + ++D + H+ +Y K D V++L+ + +V E ARV G+ ++L+RG Q +V S +LR A ++ V P Q + V+EP FY + LDF SLYPSI++A+N C++T L ES+ FG T +D +P G FVK+SV+KG+LP +L ++++ R K + + D ++LD RQL LK+ AN +G+T A GR+P + + S+ RE ++ ++V N+ + A+V+YGDTDS+ L +T +A +G E A++++ PIKL+FEKVY P +L +KKRY G Y D D + D KG+ETVRRD CP VA +L ++ L +RD + + Q +L + + L +KE + Y P EL +++ D P++G+RVPYVI T GV + P+ VL D ++ ++ YY+ Q+ P+ RIF I + + L S + G +S+Y C C + + +C C+ + + + E + +L C+ CSGS+ ++V C + DCP+ Y +V ++L + + L Q
Sbjct: 2092 LTVMTMELHARTRRDLEPDPEFDPICALFYCLSSDSTLPDSDSMQFTGAVIIDKDCKLVFTQSSRSTAPLLVRSGVAGLQVSYAAEEKELFEEVCNIMRRYDPDILVGYEVQMRSWGYLLQRASALGVDLCQQLSRVPD--AKENRFTADKDEYGADTMSEIHIVGRITINLWRIMKTEAALNNYSFENVAFHLLHQRFPLYSPRTLSDWFD------HKTHLYRWKVVDHYVSRVCGVVQLLRQQDIVGRTSEFARVFGIQFYHVLTRGSQYRVESMMLRVAKPMNYIPVTPSTQQRAQQRAPQCIPLVMEPESRFYSNSVVVLDFQSLYPSIVIAYNYCFSTCLGHVESLGTSDEFRFGCTSLRVPPDLLYQLRNDITVSPNGIAFVKASVRKGVLPRMLEEILQTRFMVKGVMKSYRDDKALHRLLDARQLGLKLIANVTFGYTSANFSGRMPSVEVGDSIVHKARETLERAIKLV----NETKKW--GARVVYGDTDSMFVLLKGATKEQAFKIGHEIAEAVTATNPKPIKLKFEKVYLPCVLQTKKRYVGYMYETVDQKDPVFDAKGIETVRRDGCPAVAKILERSVKLLFETRDISLVKQYVQRQCVKVLEAKASMQDLTFAKEY-RGSGSYRPGACIPALELTRRMMSYDRRLEPRVGERVPYVIVYGTPGV--PLIQLVRRPLEVLQDPSLRLNATYYITKQILPPVARIFSLIGVDVFSWYQELPRSATTSFRAEVGRKGTISQYFTTL-HCPVCDELT---QLGVCERCRAEPQRVVVTLQQNLRQWESQQDQLLKICRACSGSVERQVPCVSLDCPVLYKVTRVNRQLSRAPYLRQLLEQ 2921
BLAST of DNA polymerase vs. Ensembl Cavefish
Match: rev3l (REV3 like, DNA directed polymerase zeta catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-050302-55]) HSP 1 Score: 300.056 bits (767), Expect = 4.958e-83 Identity = 245/852 (28.76%), Postives = 396/852 (46.48%), Query Frame = 3
Query: 1065 IRILSFDIECAGRKGSFPDADIDPVIQI-----SNIIVRFGESEPFIKNIFTLNTC----------AP------IVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDL-------VLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDF--VLPDYQSKDGDEFTGAT--VIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIR-----EFGLTE------------DDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKREL-AIETDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKM-DCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQ--PHSELAQKIKKRDPGSAPQLGDRVPYVIT--TLGVKDKIYTKAEDPIYVL-DNNIGIDTDYYLKNQLTNPLLRIFE-------------PIFGKELATRKLLHGEHVLSKFKQQSNVGALSKY-TVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKEL 3407
+ +++ ++ R+ PD + DP+ + S+ + +S F + C AP + G V E EL E N +R DPDI+ GY Q YL+ RA+ L V L R+ +K + + G +H+ GRI +L+ I+ + L +YS V+FH L ++ + + ++D + H+ +Y K D V++L+ + +V E ARV G+ ++L+RG Q +V S +LR A ++ V P Q + V+EP FY + LDF SLYPSI++A+N C++T L ES+ FG T +D +P G FVK+SV+KG+LP +L ++++ R K + + D ++LD RQL LK+ AN +G+T A GR+P + + S+ RE ++ ++V N+ + A+V+YGDTDS+ L +T +A +G E A++++ PIKL+FEKVY P +L +KKRY G Y D D + D KG+ETVRRD CP VA +L ++ L +RD + + Q +L + + L +KE + Y P EL +++ D P++G+RVPYVI T GV + P+ VL D ++ ++ YY+ Q+ P+ RIF P K GE V K G +S+Y T + C C + + +C C+ + + + E + +L C+ CSGS+ ++V C + DCP+ Y +V ++L
Sbjct: 2036 LTVMTMELHARTRRDLEPDPEFDPICALFYCLSSDSTLPDSDSMQFTGAVIIDKDCHSAGQGSRSTAPLLVRSGVAGLQVSYAAEEKELFEEVCNIMRRYDPDILVGYEVQMRSWGYLLQRASALGVDLCQQLSRVPG-DAKENRFTADKDEYGADTMSEIHIVGRITINLWRIMKTEAALNNYSFENVAFHLLHQRFPLYSPRTLSDWFD------HKTHLYRWKVVDHYVSRVCGVVQLLRQQDIVGRTSEFARVFGIQFYHVLTRGSQYRVESMMLRVAKPMNYIPVTPSTQQRAQQRAPQCIPLVMEPESRFYSNSVVVLDFQSLYPSIVIAYNYCFSTCLGHVESLGTSDEFRFGCTSLRVPPDLLYQLRNDITVSPNGIAFVKASVRKGVLPRMLEEILQTRFMVKGVMKSYRDDKALHRLLDARQLGLKLIANVTFGYTSANFSGRMPSVEVGDSIVHKARETLERAIKLV----NETKKW--GARVVYGDTDSMFVLLKGATKEQAFKIGHEIAEAVTATNPKPIKLKFEKVYLPCVLQTKKRYVGYMYETVDQKDPVFDAKGIETVRRDGCPAVAKILERSVKLLFETRDISLVKQYVQRQCVKVLEAKASMQDLTFAKEY-RGSGSYRPGACIPALELTRRMMSYDRRLEPRVGERVPYVIVYGTPGV--PLIQLVRRPLEVLQDPSLRLNATYYITKQILPPVARIFSLIGVDVFSWYQELPRIQKSSCPSGGTVGEEVGRK-------GTISQYFTTL--HCPVCDELT---QLGVCERCRAEPQRVVVTLQQNLRQWESQQDQLLKICRACSGSVERQVPCVSLDCPVLYKVTRVNRQL 2859
BLAST of DNA polymerase vs. Ensembl Sea Lamprey
Match: pold1 (polymerase (DNA directed), delta 1, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-060429-1]) HSP 1 Score: 1126.31 bits (2912), Expect = 0.000e+0 Identity = 553/888 (62.27%), Postives = 675/888 (76.01%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTE------KISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKK--AKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNIS-SSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEK-SICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCS 3356
IYGF N K FLKVTV +P LVA KR+L +G H+ SF+ +IDF +RFMVD + GC+WIE+P Y +R ++ K+S QLEVDV + H TE EW +IAP+R+LSFDIECAGRKG FP+ + DPVIQISN+++R GE +PF++N+FTLNTCAPIVG V + E E+L+ W+ FIR +DPDIITGYN QNFDLPYL+NRA+ L V FS LGRI SMRS I ES QSKQMGRR NK +++ GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H IITDLQNG+++TR RLAVYCLKD+ L LRL+ KLM V+NY+EMARVTGVPLSYLL+RGQQIKV+SQLLR+A +D +LP + + +++ GATVIEPIKG+Y PIATLDF+SLYPSIMMAHNLCYTTLL+ K + GL+ +D+IKTP G +FVKSSV+KGLLP IL L+ ARKK AK EL ETDPFK++VLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK +VES + NG DAKVIYGDTDSVM F V TV E M +G+EAA +S FI PIKLEFEKVYYPYLLI+KKRYAG+Y+ + ++ DKMDCKG+ETVRRDN PLVANL+NTCL+K+LI RD + A+ HA+ I+DLLCNRIDISQL+I+KELT+T +EY KQ H ELA++++KRDPGSAP LGDRVPYVI Y K+EDPIYVL+NNI IDT YYL+ QL PLLRIFEPI G+ A LL GEH K S VG L + + CIGCK VL++D ++C +CK E +Y +E + ++E +FSRLWT+CQRC GSLH++VLC+
Sbjct: 203 IYGFHGNQKSNFLKVTVALPRLVAAAKRLLTQGFRFDSMPEHSYLSFEANIDFEIRFMVDHKVVGCNWIEIPAGKYQLREESASGKLPGKMSLVQLEVDVAVTDFVSHPTEGEWQAIAPLRVLSFDIECAGRKGIFPEPEKDPVIQISNMVLRQGERDPFVRNVFTLNTCAPIVGCEVHSFQHEGEMLKAWAEFIRIVDPDIITGYNIQNFDLPYLLNRASTLRVSTFSFLGRITSMRSVIKESSFQSKQMGRRDNKVINLEGRVTFDLLQVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAMLPLRLLEKLMCVINYMEMARVTGVPLSYLLTRGQQIKVVSQLLRQAMKQDLLLPVVKPEGNEDYAGATVIEPIKGYYTVPIATLDFSSLYPSIMMAHNLCYTTLLQ-KGVVENLGLSAEDFIKTPSGDHFVKSSVRKGLLPEILENLLSARKKRRAKEELKNETDPFKQKVLDGRQLALKISANSVYGFTGAQVGKLPCLEISQQSVTGFGRQMIETTKNLVESRYTTENGQKADAKVIYGDTDSVMVKFSVKTVAEGMEMGREAAAWVSSHFIPPIKLEFEKVYYPYLLINKKRYAGLYFSSSSETHDKMDCKGIETVRRDNSPLVANLINTCLQKILIDRDPDGAVDHAKDTISDLLCNRIDISQLVITKELTRTADEYAGKQAHVELAERMRKRDPGSAPNLGDRVPYVIVKATKGVAAYMKSEDPIYVLENNIPIDTQYYLEQQLAKPLLRIFEPILGENKAESILLKGEHTRCKTVLTSKVGGLMAFAKKRSTCIGCKAVLKNDAAGAVCDYCKKQESELYQKEVLHLNAMEEKFSRLWTQCQRCQGSLHEDVLCT 1089 HSP 2 Score: 68.5514 bits (166), Expect = 8.790e-12 Identity = 39/121 (32.23%), Postives = 57/121 (47.11%), Query Frame = 2
Query: 218 SKWARQNMDVVKPEIMPLIFQQLDIDNYEIKETNPRS----------VFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKIL-NQTLKQRASQHQYAENLICKVEYCLKAS 547
SKW R ++ + + L+FQQ+++D+Y K + V R +G GNS+ HVHGF PY YV GF EH F++ L N +K S + V+ C+K S
Sbjct: 82 SKWLRPSLPKIDQKTESLVFQQIELDHYIGKGFHVSGMPGATQSQVPVVRMFGITNKGNSLCCHVHGFAPYFYVAAQTGFKSEHLVSFKRELNNAVIKDMRSNKDNLSQAVLAVDICVKES 202
BLAST of DNA polymerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009864.1 (pep scaffold:Pmarinus_7.0:GL480102:12343:24944:1 gene:ENSPMAG00000008922.1 transcript:ENSPMAT00000009864.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 181.415 bits (459), Expect = 2.416e-49 Identity = 137/469 (29.21%), Postives = 233/469 (49.68%), Query Frame = 3
Query: 2079 VKSSVKKGLLPNILIQLIEARKKAKRELA-IETDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVH-DAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKM-DCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKEL-TKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVL-DNNIGIDTDYYLKNQLTNPLLRIFEPIFGKEL--ATRKLLHGEHVLSKFKQQSNVGALSKYTVIK----PKCIGCKNVLRDDEKSICAHCK--PNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQ 3443
V++SV+KG+LP +L ++++ R K + D ++L RQL LK+ AN +G+T A GR+PC+ G ++ +E +E + + N A+V+YGDTDS+ L ++ +A GKE A +++ +PIKL+FEKVY P +L +KKRY G Y + D + D KG+ETVRRD CP VA +L ++ L +D + + Q +L R + LI +KE ++ + + P +A+++ D S P+ G+RVPYVI + P +L + ++ I+ YY+ Q+ PL R+ + G ++ ++L V + Q S G K T+++ C C ++ +D IC C+ P E+A+ + +++ E R ++L C+ C+G + C + DCP + +K L I ++Q
Sbjct: 3 VQASVRKGVLPRMLEEILQTRIMVKHCMKDYRGDGALTRLLHARQLGLKLIANVTFGYTAAHFSGRMPCVE-----EQVGDSIVHKARETLERAIKQVNETKEWGARVVYGDTDSMFVLLEGASKEQAFRTGKEIAAAVTAANPSPIKLKFEKVYLPCVLQTKKRYVGYMYESLEQKDPVYDAKGIETVRRDGCPAVAKVLERSIKLLFDEKDISRVKQYVQRQCMKILEGRASMQDLIFAKEYRGRSGYKPGACVPALHVARRMFACDRRSEPRAGERVPYVIVHGAPGLPLIQLVRRPQELLQEPSLLINAPYYVSKQILPPLDRLLS-LIGVDVFRWYQQLPRSVRVWAAHHQSSAEG--RKATIVQYFSTVNCPVCGDITKD---GICGQCRQQPQEVAVLLLQQIHSQ--ERRQAQLLQICRSCTGHAEWKPPCCSTDCPTLFRLLVTEKGLCQASYIRSLIDQ 458
BLAST of DNA polymerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006446.1 (pep scaffold:Pmarinus_7.0:GL477096:156518:193524:1 gene:ENSPMAG00000005826.1 transcript:ENSPMAT00000006446.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 111.694 bits (278), Expect = 9.899e-27 Identity = 92/349 (26.36%), Postives = 153/349 (43.84%), Query Frame = 3
Query: 1056 IAPIRILSFDIECAGRKGSFPDADIDPVI------------------QISNIIVR---FGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQ-SQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITD-LQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGAT----VIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESI 2021
I + ++S ++ RK PD ++DPV ++ +IV+ G + L + + G VI E +L + DPDI+ GY Q YL+ RA L S + R M+ + TE+Q K ++H+ GR+ +L+ + + L YS V++H L E+ + ++D N R ++ Y + ++L+N+L + E+AR+ G+ +LSRG Q +V S +LR A +++ + A V+EP FY P+ LDF SLYPSI++A+N CY+T L E +
Sbjct: 2 IQHLTLMSMEMHARSRKHLVPDPNLDPVCCIFYHIMCDAPLPGRDANDVTGLIVQDAAHGTAPEDSSKDAGLPARSEVSGLDVIHVSKEDQLFHELEQIVHRFDPDILLGYEVQMLSWGYLLQRAAALKRDFKSTISR---MKVEPTETQVGVGKNEEDDDFPDIHIGGRVVLNLWSQMRSEVTLNIYSFENVAYHVLHERYPLFNFRTLSDWFDNKTGPFRWKMVDYYVCRVVGNIKLLNQLDFIGRTSELARLFGIQFHEVLSRGSQFRVESMMLRVAKPLNYIAVSPSVQQRAHMRAAECLPLVMEPESRFYSSPVLVLDFQSLYPSIIIAYNYCYSTCLGRVEHL 347
BLAST of DNA polymerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002970.1 (pep scaffold:Pmarinus_7.0:GL476977:35626:117313:1 gene:ENSPMAG00000002616.1 transcript:ENSPMAT00000002970.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 49.6766 bits (117), Expect = 4.547e-6 Identity = 69/340 (20.29%), Postives = 137/340 (40.29%), Query Frame = 3
Query: 1071 ILSFDIECAGRKGSFPDADIDPVIQISNIIVRFG----ESEPFIKNI--FTLNTCAPIVGAHVIPHKT-EAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLS--YLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLD---FASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYI 2054
+L+FDIE FPDA+ D ++ IS ++ G E ++I F G I ++ EA LL+ + + + E P+I YN +FD P++ RA + G K + + +Q+ R + ++ ++P + H L++ + + + +E E++ + Q LA Y + D+ + M V+ A T +P+ +L +G + L+ +A + V P+ Q ++ + TG + + + + L+ F S P + + L++ E+ + L E++ I
Sbjct: 257 VLAFDIETTKLPLKFPDAETDQIMMISYMVDGQGYLITNREVVSEDIEDFEFTPKPEYEGPFTIFNEADEAGLLQRFFDHLHETKPNIFVTYNGDSFDWPFVERRALAHGLDLLIETGFQKDSQGEYKATQALHMDCLRWVKRDSYLP-----------VGSHNLKAAAKAKLGYDPVELDPEEMCRMAAEEAQT--------LATYSVSDAVATYYM---YMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIVFPNKQQEEFNRLTGDGHVLDSETYVGGHVEALECGVFRSDIPCRFKMNPGVFEELMEKVETTLKHALEEEEKI 574
BLAST of DNA polymerase vs. Ensembl Yeast
Match: POL3 (Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER) [Source:SGD;Acc:S000002260]) HSP 1 Score: 948.732 bits (2451), Expect = 0.000e+0 Identity = 479/914 (52.41%), Postives = 629/914 (68.82%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSK-DGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGL-TEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLS--KFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQDLSW 3455
I+G+S + K F K+ V P +V + G + + N + +I +++R MVD G+ G SWI LP Y++ ++S CQLEV + + +I H E +W AP+RI+SFDIECAGR G FP+ + DPVIQI+N++ G +PFI+N+FTLNTC+PI G+ + H TE E+L +W NFI ++DPD+I GYNT NFD+PYL+NRA L V F GR+K+++ +I ES SK G R KNV++ GR+ DL + R++KLRSY+LNAVS HFL EQKEDV + II+DLQNGD TR RLAVYCLKD+ L LRLM KLM +VNY EMARVTGVP SYLL+RGQQIKV+SQL RK D V+P+ QS+ D++ GATVIEPI+G+YD PIATLDF SLYPSIMMAHNLCYTTL +K ++ L ++DY+ TP G YFV + ++G+LP IL +LI ARK+AK++L E DPFKR VL+GRQLALKISANSVYGFTGA G+LPCL ISSSVTA+GR MI TK V+ + NGY HDA V+YGDTDSVM FG + + EAM LG EAA+ +S F PI LEFEK Y+PYLLI+KKRYAG+++T PD FDK+D KG+ +VRRD+C LV+ ++N L+K+LI R+ + AL+ + I D+L NR+DIS+LIISK L YT+ QPH+ LA+++K+R+ G P +GDRV YVI +G DK+Y +AEDP++VL+NNI +D+ YYL NQL NP++ I PI G + A +G V+ K S G L + C CK LR E +C++C +Y + + LE ++SRLWT+CQRC+G+LH EVLCSN++C IFY R KV+KEL E++ Q W
Sbjct: 202 IWGYSGDTKLPFWKIYVTYPHMVNKLRTAFERGHLSFNSWFSNGTTTYDNIAYTLRLMVDCGIVGMSWITLPKGKYSMIEPNNRVSSCQLEVSINYRNLIAHPAEGDWSHTAPLRIMSFDIECAGRIGVFPEPEYDPVIQIANVVSIAGAKKPFIRNVFTLNTCSPITGSMIFSHATEEEMLSNWRNFIIKVDPDVIIGYNTTNFDIPYLLNRAKALKVNDFPYFGRLKTVKQEIKESVFSSKAYGTRETKNVNIDGRLQLDLLQFIQREYKLRSYTLNAVSAHFLGEQKEDVHYSIISDLQNGDSETRRRLAVYCLKDAYLPLRLMEKLMALVNYTEMARVTGVPFSYLLARGQQIKVVSQLFRKCLEIDTVIPNMQSQASDDQYEGATVIEPIRGYYDVPIATLDFNSLYPSIMMAHNLCYTTLC-NKATVERLNLKIDEDYVITPNGDYFVTTKRRRGILPIILDELISARKRAKKDLRDEKDPFKRDVLNGRQLALKISANSVYGFTGATVGKLPCLAISSSVTAYGRTMILKTKTAVQEKYCIKNGYKHDAVVVYGDTDSVMVKFGTTDLKEAMDLGTEAAKYVSTLFKHPINLEFEKAYFPYLLINKKRYAGLFWTNPDKFDKLDQKGLASVRRDSCSLVSIVMNKVLKKILIERNVDGALAFVRETINDILHNRVDISKLIISKTLAPN---YTNPQPHAVLAERMKRRE-GVGPNVGDRVDYVI--IGGNDKLYNRAEDPLFVLENNIQVDSRYYLTNQLQNPIISIVAPIIGDKQA-----NGMFVVKSIKINTGSQKGGLMSFIKKVEACKSCKGPLRKGEGPLCSNCLARSGELYIKALYDVRDLEEKYSRLWTQCQRCAGNLHSEVLCSNKNCDIFYMRVKVKKEL------QEKVEQLSKW 1097
BLAST of DNA polymerase vs. Ensembl Yeast
Match: REV3 (Catalytic subunit of DNA polymerase zeta; involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair; forms a complex with Rev7p, Pol31p and Pol32p [Source:SGD;Acc:S000006088]) HSP 1 Score: 288.5 bits (737), Expect = 1.518e-80 Identity = 235/874 (26.89%), Postives = 400/874 (45.77%), Query Frame = 3
Query: 1074 LSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPF------------IKNIFTLNTCAPIVGAH------VIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSL---LGRIK-SMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAV--YCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTG----ATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTED-------------------DYIKTPCGSYFVKSSVKKGLLPNILIQLIEAR---KKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPD-SFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKR---DPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDN-NIGIDTDYYLKNQLTNPLLRIFEPI------FGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEI---------RFSRLWTECQRCSGSL---------HQEVLCSNRDCPIFYTRKKVQKEL-----ISQDEIMERLN 3440
L+ +I R PD ID V ++I+ E E F I + + ++ P H V+ +++E E+ E ++ + +DPDI++G+ NF Y+I R K++ F + L R+K +++K++++ + G + + GR +++ L D L Y++ + +F+ L ++ + + +T++ N T V Y L + + ++L+ K + +E AR+ G+ + RG Q KV S L+R E F+L KD + V+EP FY P+ LDF SLYPSIM+ +N CY+T++ +RE LTE+ D P G + K+SV+K L +L +++ R KK E+ + KR +L+ +QLALK+ AN YG+T A GR+PC +++ S+ GRE ++ +++E +AKV+YGDTDS+ T +EA ++G A+ ++ PI L+FEKVY+P +LISKKRY G Y P + D KG+ETVRRD P ++ C+R L ++D + + Q+ + ++ +KE+ Y S++ A +K+R D + PQ +R+PY++ + + P L+ N+ +D++YY+ L PL R+F I + +E+ K +K + + VG + C C L IC+ +L C E + +L + L T C+ CS H C++ DCP+FY+R K ++ L + ++E + LN
Sbjct: 670 LTLEIHANTRSDKIPDPAIDEV----SMIIWCLEEETFPLDLDIAYEGIMIVHKASEDSTFPTKIQHCINEIPVMFYESEFEMFEALTDLVLLLDPDILSGFEIHNFSWGYIIERCQKIH--QFDIVRELARVKCQIKTKLSDTWGYAHSSG------IMITGRHMINIWRALRSDVNLTQYTIESAAFNILHKRLPHFSFESLTNMWNAKKSTTELKTVLNYWLSRAQINIQLLRKQDYIARNIEQARLIGIDFHSVYYRGSQFKVESFLIRICKSESFILLSPGKKDVRKQKALECVPLVMEPESAFYKSPLIVLDFQSLYPSIMIGYNYCYSTMIGR---VREINLTENNLGVSKFSLPRNILALLKNDVTIAPNGVVYAKTSVRKSTLSKMLTDILDVRVMIKKTMNEIGDDNTTLKR-LLNNKQLALKLLANVTYGYTSASFSGRMPCSDLADSIVQTGRETLEKAIDIIEKD------ETWNAKVVYGDTDSLFVYLPGKTAIEAFSIGHAMAERVTQNNPKPIFLKFEKVYHPSILISKKRYVGFSYESPSQTLPIFDAKGIETVRRDGIPAQQKIIEKCIRLLFQTKDLSKIKKYLQNEFFKIQIGKVSAQDFCFAKEVKLG--AYKSEKTAPAGAVVVKRRINEDHRAEPQYKERIPYLVVKGKQGQLLRERCVSPEEFLEGENLELDSEYYINKILIPPLDRLFNLIGINVGNWAQEIVKSK--RASTTTTKVENITRVGTSA-------TCCNCGEEL----TKICSL----QLCDDCLEKRSTTTLSFLIKKLKRQKEYQTLKTVCRTCSYRYTSDAGIENDHIASKCNSYDCPVFYSRVKAERYLRDNQSVQREEALISLN 1502
BLAST of DNA polymerase vs. Ensembl Yeast
Match: POL1 (Catalytic subunit of the DNA polymerase I alpha-primase complex; required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis [Source:SGD;Acc:S000005046]) HSP 1 Score: 161.384 bits (407), Expect = 1.782e-40 Identity = 163/644 (25.31%), Postives = 295/644 (45.81%), Query Frame = 3
Query: 1302 DPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHM------PGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKE----DVAHQIITDLQNGDDRTRHRLAVY-----CLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQS------------KDGD--------EFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDK-------MDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLL----CNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDP-------------IYVLDNNIGIDTDYYLKNQLTNPLLRIFEPI 3056
DPD+I G+ QN L L +R + LN+ FS +GR +R ++ ++ GR + H GR+ D+ + + + S + + + +KE D+ +Q + Q +D +A+ C+ +++ R+ +L+ + ++ + G + L + + LL + + F++PD + ++ D ++ G V EP KG + + +DF SLYPSI+ N+C+TT+ ++KE I D+ P S V +G+LP +L L++ R++ K+ + ETDP KR D RQ ALK++ANS+YG G R ++ VT GRE++ T+++ ES + V+YGDTDSVM G +A+ +G + ++ ++ ++++ + V+ LL +KK+YA + + DK ++ KG++ RR+ CPL ++ L +L +D AL + D+ N I I + I+ +L+K + Y + + ++ R G + G + +VIT +D+I A+ P + + NN+ D YYL+ Q+ P+ R+ E I
Sbjct: 631 DPDVIIGHRLQNVYLDVLAHRMHDLNIPTFSSIGR--RLR------RTWPEKFGRGNSNMNHFFISDICSGRLICDIANEMGQSLTPKCQSWDLSEMYQVTCEKEHKPLDIDYQ---NPQYQNDVNSMTMALQENITNCMISAEVSYRI--QLLTLTK--QLTNLAGNAWAQTLGGTRAGRNEYILLHEFSRNGFIVPDKEGNRSRAQKQRQNEENADAPVNSKKAKYQGGLVFEPEKGLHKNYVLVMDFNSLYPSIIQEFNICFTTVDRNKEDI-------DELPSVP------PSEVDQGVLPRLLANLVDRRREVKKVMKTETDPHKRVQCDIRQQALKLTANSMYGCLGYVNSRFYAKPLAMLVTNKGREILMNTRQLAES---------MNLLVVYGDTDSVMIDTGCDNYADAIKIGLGFKRLVNERYRL-LEIDIDNVFKKLLLHAKKKYAALTV----NLDKNGNGTTVLEVKGLDMKRREFCPLSRDVSIHVLNTILSDKDPEEALQEVYDYLEDIRIKVETNNIRIDKYKINMKLSKDPKAYPGGKNMPAVQVALRMRKAGRVVKAGSVITFVITK---QDEIDNAADTPALSVAERAHALNEVMIKSNNLIPDPQYYLEKQIFAPVERLLERI 1229
BLAST of DNA polymerase vs. Ensembl Nematostella
Match: EDO49294 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A7RH52]) HSP 1 Score: 1187.17 bits (3070), Expect = 0.000e+0 Identity = 572/920 (62.17%), Postives = 708/920 (76.96%), Query Frame = 3
Query: 729 IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVR----------PQTEKISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQDLSW 3455
IYG+ +N K FLKVTV + L+A KR+L G HY ++++++ID+ VRFMVDS + GC+WIELP Y VR + S CQLEVDV WD++I H E +W IAP+RILSFDIECAGRKG FP+A+ DPVIQI+N+++R GE +PFI+N+FTL CAPIVG+HV+ EA+L + WS F++E DPDIITGYN NFDLPYL+NRA L+V FSLLGRI + +S +T + QSK G+R NK +++ GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H II+DLQNG+D+TR RLA+YC+KD+ L LRL+ KLM V+NY+EMARVTGVP+ YLLSRGQQIKV+SQLLRK D V+P ++++ G+E+ GATVIEP KG+Y+ PIATLDF+SLYPSIMMAHNLCYT+LL + ++E D YIKTP G++FVK SV+KGLLP IL L+ ARKKAK +L ETDPFK++VLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVTAFGR MI+ TKE+VE+ + ANGY DAKVIYGDTDSVM FGV TV E+M LG EAA+ +S F+ PIKLEFEKVY+PYLLISKKRYAG+Y+TKPD DKMDCKG+ETVRRDNCPLVANL+N CL+KLLI R+ A+ + + VI+DLLCNRIDISQL+I+KELTKT EEY KQ HSELA++++KRD GSAP+LGDRVPYVI K Y KAEDPIYVL+NN+ IDT YYL+NQL+ PLLRIFEPI G+ A+ LL GEH +K S VG LS +T + CIGCK +L DD ++C HCK E ++ +E ++ + LE RF+RLWT+CQ C+GSLHQ+VLC++RDCPIFY R KVQK+L +QD+ + R D W
Sbjct: 177 IYGYHKNTKIPFLKVTVALQKLIAPAKRILETGFRCGHYPERGYSTYESNIDYEVRFMVDSDIVGCNWIELPAGKYRVRTPNGIASRYRSSAKPESRCQLEVDVAWDELISHEPEGDWSKIAPVRILSFDIECAGRKGIFPEAEKDPVIQIANMVIRQGEKDPFIRNVFTLGGCAPIVGSHVLSFDKEADLFKAWSEFVQECDPDIITGYNIVNFDLPYLLNRATALHVNNFSLLGRIVADKSTVTSTTFQSKAYGKRENKVINISGRVQFDLLHVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHNIISDLQNGNDQTRRRLAIYCMKDAILPLRLLEKLMCVINYMEMARVTGVPMGYLLSRGQQIKVMSQLLRKTHQTDLVIPAHKAEAGEEYAGATVIEPNKGYYNIPIATLDFSSLYPSIMMAHNLCYTSLLHPSQ-VKE--TPPDQYIKTPSGNFFVKKSVRKGLLPEILEHLLTARKKAKADLKKETDPFKKKVLDGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTAFGRMMIERTKELVEAKYTVANGYKTDAKVIYGDTDSVMVRFGVETVAESMELGNEAAEYVSEHFVKPIKLEFEKVYFPYLLISKKRYAGLYFTKPDKHDKMDCKGIETVRRDNCPLVANLINACLKKLLIERNPQGAVEYTKQVISDLLCNRIDISQLVITKELTKTGEEYAGKQAHSELAERMRKRDAGSAPKLGDRVPYVIIAGAKGAKAYEKAEDPIYVLENNVPIDTGYYLENQLSKPLLRIFEPILGESKASSALLKGEHTRTKTIVTSTVGKLSMFTKKRSTCIGCKALLDDDGSAVCKHCKSRESELFQKEIEHLRVLEERFARLWTQCQNCTGSLHQDVLCTSRDCPIFYMRTKVQKDLANQDKQVSRFG-DCFW 1092 HSP 2 Score: 79.337 bits (194), Expect = 6.340e-15 Identity = 49/176 (27.84%), Postives = 76/176 (43.18%), Query Frame = 2
Query: 47 NSFQKNKTYAPSSKISKFEVKNNDEDDVSMDEWNHEPEEICFEMESNTETVKETDEFSKWARQNMDVVKPEIMPLIFQQLDIDNY--------EIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQ-TLKQRASQHQYAENLICKVEYCLKAS 547
+S QK K + SK +D D + E + + + ET KW R + +P + FQQLD++NY + P + R +G +GNS++ H+HGF PY +V PPGF + HC FR L++ L S + V+Y ++ S
Sbjct: 2 DSSQKRKGAFGTGNASKRSRNQDDLDGSQPSSFESELASLQGD-DGAVETATRGRPSDKWPRPALPPFEPASDNIQFQQLDVENYIGTPLLGMPGSKVGPVPIIRMFGVTMDGNSVLCHIHGFVPYFFVPAPPGFQEIHCSLFRDTLDKAVLNDMRSNRDGVTQAVLAVDYMMRES 176
BLAST of DNA polymerase vs. Ensembl Nematostella
Match: EDO42056 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A7S2J9]) HSP 1 Score: 243.047 bits (619), Expect = 4.393e-70 Identity = 163/497 (32.80%), Postives = 251/497 (50.50%), Query Frame = 3
Query: 1251 KTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGD-DRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVL--PDYQSKDGDEFTGAT--VIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIRE-----FGLT------------EDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETD-PFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKM-DCKGMETVRRDNCPLVANL 2666
K E +L RE DPD++ GY Q YLI RA ++ S L R+ S + S+ Q G + + GRI +++ ++ + L YS V+FH L E+ ++ ++D + D R R + + +RL+ +L + E+AR+ G+ ++SRG Q +V S +LR A +++ P Q ++ V+EP FY P+ LDF SLYPS+M+A+N CY+T L SI E FG E D +P G FVKS+V++G+LP +L ++ R K + D ++LD RQL LK+ AN YG+T A GR+PC+ I+ S+ RE ++ ++V ++ A+V+YGDTDS+ L + EA +G E ++++ + P+KL+FEKVY P +L +KKRY G Y D + + D KG+ETVRRD CP VA +
Sbjct: 4 KKEKDLFPALLGLFREWDPDVLIGYEVQMLSWGYLIQRALVFDLDLASKLARVSGS-SSSSNMDSEKDQWGAAHASEIKIAGRIVLNVWRLMRHEVTLNVYSFENVAFHVLHERIPLFPYRSLSDWWDHKTDMHRWRTVQHYVTRCCGNVRLLEQLDFIGRTSELARLFGILFYSVISRGSQFRVESMMLRIAKPMNYIAASPSVQQRNSMRAPEVIPLVLEPESRFYHHPVLVLDFQSLYPSMMIAYNYCYSTCLGRVSSIAEGSHFKFGALSLSEPPSLLKQLERDIHISPNGVAFVKSNVRRGVLPRMLEDILNTRIMVKNSMKKWKDNKSTYRMLDARQLGLKLIANVTYGYTSANFSGRMPCVEIADSIVRKARETLERAIDLVNTTSKWG------ARVVYGDTDSLFVLLKGVSKDEAFRIGHEITETVTAQNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETADQKEAVFDAKGIETVRRDTCPAVAKV 493
BLAST of DNA polymerase vs. Ensembl Nematostella
Match: EDO39342 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A7SAB6]) HSP 1 Score: 183.726 bits (465), Expect = 6.119e-47 Identity = 168/599 (28.05%), Postives = 289/599 (48.25%), Query Frame = 3
Query: 1236 HVIPHK-------TEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPD--YQSK-----DGDE-------------FTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKREL-AIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSF---DKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQ----SVIADLLCNRIDISQLIISKELTKTDEEYTSKQ--PHSELAQKI--KKRDPGSAPQLGDRVPYVI 2915
H IP +E LL I +IDPD++ G++ FDL L++R + + +S +GR+K RS + + + + G ++ V GR+ D+ + + +SY L+ +S L+ ++++ I ++ N H L + + DS L LR+M +L V+ ++ + G LS L G+ + LL + ++ PD Y K D D+ + G V+EP KGFYDK I LDF SLYPSI+ +N+C+TT+ ++S ++ EDD + P G+LP + +L+E R++ K + + D K D RQ ALK++ANS+YG G R +++ VT+ GRE++ TK++V+ VIYGDTDS+M + + E +G + + + P+ V ++L S RYA + ++ + + + KG++ VRRD C L + N L ++L ++ + A + + ++ D+ ++D+ + +I+K+LTK +Y K+ PH +A + K R G +GD +PYVI
Sbjct: 393 HCIPQHLKIDVMASERALLAFVVAKIHKIDPDVLVGHDIFGFDLDILLHRISACKIPQWSRIGRLK--RSIMPKVRLSLGRGGHNVDPTVTC-GRLLCDVKISSRELIRSKSYDLSELSRVVLQTPRQELDQDDIGNMYNTSQELLHLLELTTV-DSLLTLRIMYELNVLPLAHQITTIAGNVLSRTLLGGRSKRNEFLLLHAFHEKGYICPDKSYGKKQVVREDDDDHVTTTKKGRRKPAYAGGLVLEPKKGFYDKFILLLDFNSLYPSIIQEYNICFTTI--DRKSAKD---EEDDIVDLP------DMDQDPGILPTEIRKLVERRRQVKGMMKTVSRDSDKYLQYDIRQKALKLTANSMYGCLGFSHSRFYAKPLAALVTSKGREILMKTKDLVQQMH---------LDVIYGDTDSIMINTNSTDLQEVKKVGNKVRHPHATYLVLPVSYTLRFVNLLHILFS--RYAAIMISENEDGTMNEVKEMKGLDIVRRDWCDLAKDAGNYVLSQILSAQSREAIVDNVHDFLITIGEDVKGGKVDLQKYVINKQLTKAPHDYPDKKSLPHVHVALWLMSKSRKVG----VGDTIPYVI 961
BLAST of DNA polymerase vs. Ensembl Nematostella
Match: EDO27819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T875]) HSP 1 Score: 68.5514 bits (166), Expect = 1.673e-12 Identity = 54/193 (27.98%), Postives = 96/193 (49.74%), Query Frame = 3
Query: 2535 YPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQ----SVIADLLCNRIDISQLIISKELTKTDEEYTSKQ--PHSELAQKI--KKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVL-----DNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELA 3074
Y ++IS+ M K + KG++ VRRD C L + N L ++L ++ + A + + ++ D+ ++D+ + +I+K+LTK +Y K+ PH +A + K R G +GD +PYVI + + + T Y+L +++ IDT YYL NQ+ + R+ +PI G + A
Sbjct: 31 YAAIMISENEDGTMNEVK-------EMKGLDIVRRDWCDLAKDAGNYVLSQILSAQSREAIVDNVHDFLITIGEDVKGGKVDLQKYVINKQLTKAPHDYPDKKSLPHVHVALWLMSKSRKVG----VGDTIPYVICDVSMHLPLVTCGALVHYLLHEFRKSDSLKIDTKYYLANQVHPVVARLCDPIDGTDSA 212
BLAST of DNA polymerase vs. Ensembl Medaka
Match: pold1 (DNA polymerase delta 1, catalytic subunit [Source:NCBI gene;Acc:101155199]) HSP 1 Score: 1154.81 bits (2986), Expect = 0.000e+0 Identity = 556/919 (60.50%), Postives = 694/919 (75.52%), Query Frame = 3
Query: 726 DIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTE------------KISFCQLEVDVQWDKIICHSTE-EWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYY-TKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLN 3440
++YG+ FL++T+ +P L+A KR+L +G H+ SF+ +IDF +RFMVDS + GC WIELP + + +R + K+S CQ EVDV W +I H E EW IAP+R+LSFDIECAGRKG FP+ D DPVIQI++++ R GE+EPFI+ +FTL +C IVG+ ++ E +LL+ W+ F+R +DPDIITGYN QNFD PYLINRA L V F LGR+++M+S + ES QSKQMGRR NK ++M GR+ FDL +LLRD+KLRSY+LNAVSFHFL+EQKEDV H II+DLQNG+++TR RLAVYCLKD+ L LRL+ KLM V+NY+EMARVTGVPLSYLLSRGQQIKV+SQLLR+A ++ V+P +++ G+++TGATVIEP KG+Y PI TLDF+SLYPSIMMAHNLCYTTLL+ K S+ L+ +D+IKTP G FVKSSV+KGLLP IL L+ ARK+AK EL ETDPFK+QVLDGRQLALKISANSVYGFTGAQ G+LPCL IS SVT FGR+MI+ TK++VES + +NGY DAKVIYGDTDSVM GV+TV EAM +G+EAA+ +S F PIKLEFEKVYYPYLLI+KKRYAG+Y+ + D+ DKMDCKG+ETVRRDNCPLVANL+NTCL+K+LI RD A+ HA+ VI+DLLCNRIDISQL+I+KELT+T +EY KQ H ELA++++KRD GSAP LGDRVPYVI Y K+EDPIYVL+N I IDT YYL+ QL+ PLLRIFEPI G+ A LL G+H K S VG L + + CIGCK VL+ DE ++C CK E +Y +E + +LE RFSRLWT+CQRC GSLH++VLC++RDCPIFY RKKVQK+L Q +++ R
Sbjct: 190 NMYGYHGQQSMDFLRITMAMPRLIAPAKRLLEQGFKFGHFPIQGYQSFEANIDFEIRFMVDSNVVGCCWIELPKDKWRLREERSTSTGEVDSQTPVKVSLCQYEVDVAWTDLISHPAEGEWQRIAPLRVLSFDIECAGRKGIFPEPDKDPVIQIASMVQRQGETEPFIRTVFTLQSCTSIVGSQILCFTQEKQLLQSWAEFLRTVDPDIITGYNIQNFDFPYLINRAAALKVTYFPYLGRVRNMKSVLKESNFQSKQMGRRENKTINMEGRVQFDLLQVLLRDYKLRSYTLNAVSFHFLQEQKEDVQHSIISDLQNGNEQTRRRLAVYCLKDAYLPLRLLQKLMCVINYMEMARVTGVPLSYLLSRGQQIKVVSQLLRQAMKQNLVMPVVKTEGGEDYTGATVIEPEKGYYSVPITTLDFSSLYPSIMMAHNLCYTTLLQ-KGSVERLQLSSEDFIKTPTGDQFVKSSVRKGLLPEILENLLSARKRAKAELKKETDPFKKQVLDGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIERTKQLVESKYTISNGYQADAKVIYGDTDSVMVKLGVATVKEAMEIGREAAEWVSSHFTPPIKLEFEKVYYPYLLINKKRYAGLYFSSSADTHDKMDCKGIETVRRDNCPLVANLINTCLQKILIDRDPQGAVDHAKEVISDLLCNRIDISQLVITKELTRTAQEYAGKQAHVELAERMRKRDAGSAPNLGDRVPYVIIKAAKGAAAYMKSEDPIYVLENTIPIDTQYYLEQQLSKPLLRIFEPILGESKAESVLLKGDHTRCKTVLTSKVGGLMAFAQKRSTCIGCKAVLKTDE-AVCDFCKKKESELYQKEIFHLNTLEERFSRLWTQCQRCQGSLHEDVLCTSRDCPIFYMRKKVQKDLDDQSKLVSRFG 1106 HSP 2 Score: 75.8702 bits (185), Expect = 2.159e-13 Identity = 36/95 (37.89%), Postives = 52/95 (54.74%), Query Frame = 2
Query: 221 KWARQNMDVVKPEIMPLIFQQLDIDNY----------EIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTL 475
+W R + + P L+FQQ+D+D+Y +++E P + R +G NGNS+ HVHGF PY YV P GF E GEF++ LN +
Sbjct: 73 RWPRPHAPTLNPSSETLVFQQIDLDHYLGASVAGMPGQLQEKVP--IIRMFGVTDNGNSVCCHVHGFAPYFYVPAPNGFKSEFLGEFKRELNSAV 165
BLAST of DNA polymerase vs. Ensembl Medaka
Match: rev3l (REV3 like, DNA directed polymerase zeta catalytic subunit [Source:NCBI gene;Acc:101170069]) HSP 1 Score: 291.967 bits (746), Expect = 2.547e-80 Identity = 236/833 (28.33%), Postives = 391/833 (46.94%), Query Frame = 3
Query: 1050 PSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKN---IFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITD-LQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDF--VLPDYQSKDGDEFTGAT--VIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIR-----EFGLT------------EDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAI-ETDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKM-DCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSK-QPHSELAQKIKKRDPGSAPQLGDRVPYVIT--TLGVKDKIYTKAEDPIYVL-DNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRD----------DEKS---ICAHCK--PNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKEL 3407
P PI L + C PDAD Q++ I+ + EP + L + + G V E L + +R +DPDI+ GY Q YL+ RA L V L R+ SK ++ + G +H+ GR+ +L+ ++ + L SYS V+FH L ++ +H+ ++D + + R ++ + + + L+ + +V E+AR+ G+ ++L+RG Q +V S +LR A ++ V P Q + V+EP FY + LDF SLYPSI++A+N C++T L +ES+ +FG T +D +P G FVKS+V+KG+LP +L +++ R K+ + + D ++LD RQL LK+ AN +G+T A GR+P + + S+ RE ++ + V + K G A+V+YGDTDS+ L +T +A +G E A++++ P+KL+FEKVY P +L +KKRY G Y D + + D KG+ETVRRD CP V+ +L ++ L +RD + Q +L R + L +KE + P EL +++ D P++G+RVPYV+ T GV + P+ VL D + ++ YY+ Q+ PL R+F+ L G V S +++ V S +G K + DE + +C+ C+ P +A+ + + E + +L C+ CSG ++V C + DCP+ Y +V +++
Sbjct: 2151 PEFDPICALFY---CFSSDAPLPDAD---STQLTGAIMVDKDHEPGGRGRRETAPLLVRSGVSGLQVTYASEEKMLFQELVGIMRRLDPDILLGYEVQMHSWGYLLQRAAVLGVDLCQQLSRVPG-DSKENRFAAEKDEYGADTMTEIHIIGRVTLNLWRVMKSEVALNSYSFENVAFHVLHQRFPLFSHRTLSDWFDHNTNLYRWKMVDHYVSRVCSSMHLLQQNDIVGRTSELARLFGIQFLHVLTRGSQYRVESMMLRVAKPLNYIPVTPSVQQRAQQRAPQCIPLVMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHQESLGTPDEFKFGCTSLRVPPEMLYQLRNDINVSPSGIAFVKSTVRKGVLPRMLEEILNTRIMVKQSMKTYKQDKALMKLLDARQLGLKLIANVTFGYTSANYSGRMPSVEVGDSIVHKARETLERAIKQVNDT--KKWG----ARVVYGDTDSMFVLLKGATKEQAFRIGNEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYESLDQKEPVFDAKGIETVRRDGCPAVSKILERSIKLLFETRDISQVKQFVQCQCLKVLDGRASMQDLTFAKEYRGSGSYRPGACVPALELTRRMLSYDRRLEPRVGERVPYVVVYGTPGV--PLIQLVRRPLDVLQDPTLRLNATYYITKQILPPLARMFQ------------LIGVDVFSWYQELPRVQKASCSAAAAGDEVGRKGTISQYFTTLHCPVCDELTQLGVCSQCRAEPQRVAVTLYQDM--RQWESQQEQLLKICRSCSGGTERQVPCISLDCPVLYKLSRVNRQI 2954
BLAST of DNA polymerase vs. Ensembl Medaka
Match: pola1 (DNA polymerase alpha 1, catalytic subunit [Source:NCBI gene;Acc:101165771]) HSP 1 Score: 180.644 bits (457), Expect = 1.646e-45 Identity = 171/637 (26.84%), Postives = 305/637 (47.88%), Query Frame = 3
Query: 1254 TEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRR---INKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQS---------------KDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLK-SKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIE-TDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGM---YYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIAD----LLCNRIDISQLIISKELTKTDEEYTSKQ--PHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDN-----NIGIDTDYYLKNQLTNPLLRIFEPIFG 3062
TE LL + + +IDPD++ G++ FDL L+ R N V +S +GR++ ++ ++G R KN GR+ D+ + + +SY L ++ L+ ++ V + + +L + + L + D+ L+L++M +L V+ +++ + G LS L G+ + LL +++++PD S + ++G V++P GFYD+ + LDF SLYPSI+ N+C+TT+ + ++ S R+ + E I P ++ G+LP + +L+E RK+ K+ + + +P D RQ ALK++ANS+YG G R +++ VT GRE++ TK+MV+ + +VIYGDTDS+M ++ E LG + ++ K ++++ + V+ LL+ KK+YA + ++ K + KG++ VRRD C L N + ++L + ++ + + Q + + + I ++ I K LTK ++Y K+ PH +A I + G + GD + Y+I KD A Y L+ + +DT YYL Q+ + RI EPI G
Sbjct: 610 TERTLLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLR---------RANMPKLGGRGLFAEKNATC-GRLVCDVEISAKELIRCKSYHLTELAAQVLKVERVTVPQEEVKNLYSDSPHLLYLLEL-TWTDAKLILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFHDKNYIVPDKPSFKKAQLEMVGTFKKTRKKAAYSGGLVLDPKVGFYDQFVLLLDFNSLYPSIIQEFNICFTTVQREAQNSRRKREVEEIPEIPDP--------GLEMGILPKEIRKLVERRKQVKQLMKQQDINPDLYMQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKDMVQKM---------NLEVIYGDTDSIMINTNSKSLEEVFKLGNKVKAEVN-KLYKLLEIDIDGVFKSLLLLKKKKYAALVVEHHGDGRYSVKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQSRDIIVENIQKHLVEVGERVANGDIPLNLYEIHKALTKDPQDYPDKKSLPHVHVALWINSQG-GRRVKAGDTISYLI----CKDGSTLAASQRAYALEQLQKQEGLSVDTQYYLAQQIHPVVSRICEPIEG 1212
BLAST of DNA polymerase vs. Ensembl Medaka
Match: pola1 (DNA polymerase alpha 1, catalytic subunit [Source:NCBI gene;Acc:101165771]) HSP 1 Score: 177.563 bits (449), Expect = 1.377e-44 Identity = 170/643 (26.44%), Postives = 306/643 (47.59%), Query Frame = 3
Query: 1254 TEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRR---INKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQS--------KDGDE--------------FTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIE-TDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGM---YYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIAD----LLCNRIDISQLIISKELTKTDEEYTSKQ--PHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDN-----NIGIDTDYYLKNQLTNPLLRIFEPIFG 3062
TE LL + + +IDPD++ G++ FDL L+ R N V +S +GR++ ++ ++G R KN GR+ D+ + + +SY L ++ L+ ++ V + + +L + + L + D+ L+L++M +L V+ +++ + G LS L G+ + LL +++++PD S DG+E ++G V++P GFYD+ + LDF SLYPSI+ N+C+TT+ + ++ R + + ++ ++ G+LP + +L+E RK+ K+ + + +P D RQ ALK++ANS+YG G R +++ VT GRE++ TK+MV+ + +VIYGDTDS+M ++ E LG + ++ K ++++ + V+ LL+ KK+YA + ++ K + KG++ VRRD C L N + ++L + ++ + + Q + + + I ++ I K LTK ++Y K+ PH +A I + G + GD + Y+I KD A Y L+ + +DT YYL Q+ + RI EPI G
Sbjct: 613 TERTLLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLR---------RANMPKLGGRGLFAEKNATC-GRLVCDVEISAKELIRCKSYHLTELAAQVLKVERVTVPQEEVKNLYSDSPHLLYLLEL-TWTDAKLILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFHDKNYIVPDKPSFKKAQLEMGDGEEDVDAGKGKRKKKAAYSGGLVLDPKVGFYDQFVLLLDFNSLYPSIIQEFNICFTTVQREAQNSRR----KREEDESEEIPEIPDPGLEMGILPKEIRKLVERRKQVKQLMKQQDINPDLYMQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKDMVQKM---------NLEVIYGDTDSIMINTNSKSLEEVFKLGNKVKAEVN-KLYKLLEIDIDGVFKSLLLLKKKKYAALVVEHHGDGRYSVKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQSRDIIVENIQKHLVEVGERVANGDIPLNLYEIHKALTKDPQDYPDKKSLPHVHVALWINSQG-GRRVKAGDTISYLI----CKDGSTLAASQRAYALEQLQKQEGLSVDTQYYLAQQIHPVVSRICEPIEG 1225
BLAST of DNA polymerase vs. Ensembl Medaka
Match: pola1 (DNA polymerase alpha 1, catalytic subunit [Source:NCBI gene;Acc:101165771]) HSP 1 Score: 177.178 bits (448), Expect = 2.158e-44 Identity = 170/643 (26.44%), Postives = 306/643 (47.59%), Query Frame = 3
Query: 1254 TEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRR---INKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQS--------KDGDE--------------FTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIE-TDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGM---YYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIAD----LLCNRIDISQLIISKELTKTDEEYTSKQ--PHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDN-----NIGIDTDYYLKNQLTNPLLRIFEPIFG 3062
TE LL + + +IDPD++ G++ FDL L+ R N V +S +GR++ ++ ++G R KN GR+ D+ + + +SY L ++ L+ ++ V + + +L + + L + D+ L+L++M +L V+ +++ + G LS L G+ + LL +++++PD S DG+E ++G V++P GFYD+ + LDF SLYPSI+ N+C+TT+ + ++ R + + ++ ++ G+LP + +L+E RK+ K+ + + +P D RQ ALK++ANS+YG G R +++ VT GRE++ TK+MV+ + +VIYGDTDS+M ++ E LG + ++ K ++++ + V+ LL+ KK+YA + ++ K + KG++ VRRD C L N + ++L + ++ + + Q + + + I ++ I K LTK ++Y K+ PH +A I + G + GD + Y+I KD A Y L+ + +DT YYL Q+ + RI EPI G
Sbjct: 617 TERTLLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLR---------RANMPKLGGRGLFAEKNATC-GRLVCDVEISAKELIRCKSYHLTELAAQVLKVERVTVPQEEVKNLYSDSPHLLYLLEL-TWTDAKLILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFHDKNYIVPDKPSFKKAQLEMGDGEEDVDAGKGKRKKKAAYSGGLVLDPKVGFYDQFVLLLDFNSLYPSIIQEFNICFTTVQREAQNSRR----KREEDESEEIPEIPDPGLEMGILPKEIRKLVERRKQVKQLMKQQDINPDLYMQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKDMVQKM---------NLEVIYGDTDSIMINTNSKSLEEVFKLGNKVKAEVN-KLYKLLEIDIDGVFKSLLLLKKKKYAALVVEHHGDGRYSVKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQSRDIIVENIQKHLVEVGERVANGDIPLNLYEIHKALTKDPQDYPDKKSLPHVHVALWINSQG-GRRVKAGDTISYLI----CKDGSTLAASQRAYALEQLQKQEGLSVDTQYYLAQQIHPVVSRICEPIEG 1229
BLAST of DNA polymerase vs. Planmine SMEST
Match: SMESG000033372.1 (SMESG000033372.1) HSP 1 Score: 1836.23 bits (4755), Expect = 0.000e+0 Identity = 891/910 (97.91%), Postives = 892/910 (98.02%), Query Frame = 3
Query: 726 DIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTEEWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQDLSW 3455
+IYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYT WDKIICHSTEEWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQDLSW
Sbjct: 172 NIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYT------------------WDKIICHSTEEWPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLALKISANSVYGFTGAQRGRLPCLNISSSVTAFGREMIDFTKEMVESSFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQDLSW 1063 HSP 2 Score: 367.466 bits (942), Expect = 5.813e-109 Identity = 171/171 (100.00%), Postives = 171/171 (100.00%), Query Frame = 2
Query: 32 MSRRPNSFQKNKTYAPSSKISKFEVKNNDEDDVSMDEWNHEPEEICFEMESNTETVKETDEFSKWARQNMDVVKPEIMPLIFQQLDIDNYEIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLKQRASQHQYAENLICKVEYCLKA 544
MSRRPNSFQKNKTYAPSSKISKFEVKNNDEDDVSMDEWNHEPEEICFEMESNTETVKETDEFSKWARQNMDVVKPEIMPLIFQQLDIDNYEIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLKQRASQHQYAENLICKVEYCLKA
Sbjct: 1 MSRRPNSFQKNKTYAPSSKISKFEVKNNDEDDVSMDEWNHEPEEICFEMESNTETVKETDEFSKWARQNMDVVKPEIMPLIFQQLDIDNYEIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLKQRASQHQYAENLICKVEYCLKA 171
BLAST of DNA polymerase vs. Planmine SMEST
Match: SMESG000033513.1 (SMESG000033513.1) HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0 Identity = 319/499 (63.93%), Postives = 396/499 (79.36%), Query Frame = 3
Query: 726 DIYGFSQNLKKAFLKVTVPVPSLVATTKRVLVEGMTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEKISFCQLEVDVQWDKIICHSTEE-WPSIAPIRILSFDIECAGRKGSFPDADIDPVIQISNIIVRFGESEPFIKNIFTLNTCAPIVGAHVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDLQNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFVLPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLLKSKESIREFGLTEDDYIKTPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIETDPFKRQVLDGRQLAL 2219
+IYG+SQ+ K F+K+T+ +PSL++T KR+L EG+ IP+ G+HNL++FD +IDF++RFMVDSG GCSWIELP N+Y +R + K+S CQLEVDV W I H + W I PIRI+SFD+ C KGS P+ + DPVIQISN ++RFGE EPFI+ IFTLN+C P+VGA V H TE +LL+HWS FIREIDPD+I+GYNTQ DLPYLINRA KLN+ F+LLGRIK +S I S QSKQ GR+ K VHM GR+ FDL I+ RD+KLRSYSL+AV+FHF EEQK+ +HQ+ITDLQNG + TRHRLAVY +K S L LRL+NKLM+V+NYVEMARV GVPLSYLL RGQ IKVLS +LRKA DFVLPDY++ ++++G +IEP +G+Y KPIA LDFASLYPSIM+AHNLCYTTLL+ K I++FGL+E DY KTP SYFVKSSVKKGLLP IL++L++ARKK K+E+A E+D F +QVLDGRQLA+
Sbjct: 167 NIYGYSQDKKFNFIKITLLLPSLLSTCKRLLEEGLIIPNCGFHNLSAFDINIDFTLRFMVDSGFVGCSWIELPTNSYQIRCEESKMSLCQLEVDVNWKLITYHPPNKYWSHIVPIRIISFDVMCFSTKGSSPNPETDPVIQISNTVMRFGEQEPFIQCIFTLNSCVPLVGAKVFQHDTEEDLLKHWSQFIREIDPDLISGYNTQTLDLPYLINRAKKLNIIHFNLLGRIKFAQSLIGISSLQSKQFGRKSYKIVHMAGRVDFDLKQIISRDYKLRSYSLHAVAFHFFEEQKQKFSHQVITDLQNGTEFTRHRLAVYSVKTSFLSLRLINKLMLVINYVEMARVAGVPLSYLLLRGQSIKVLSLILRKAKENDFVLPDYKANSSEQYSGGLIIEPERGYYTKPIAVLDFASLYPSIMIAHNLCYTTLLRDKNIIKQFGLSESDYSKTPIESYFVKSSVKKGLLPVILLELLDARKKTKQEMACESDLFMKQVLDGRQLAI 665 HSP 2 Score: 115.546 bits (288), Expect = 5.146e-26 Identity = 56/124 (45.16%), Postives = 75/124 (60.48%), Query Frame = 2
Query: 173 EMESNTETVKETDEFSKWARQNMDVVKPEIMPLIFQQLDIDNYEIKETNPRSVFRFYGANQNGNSIIAHVHGFYPYLYVEPPPGFLKEHCGEFRKILNQTLKQRASQHQYAENLICKVEYCLKA 544
+ S E + T+EF+ W R + MP+IFQQ+DID+Y I +NP VFR +G N++GNSI+A +HGFYPY YV+ P F C FR LN+ LK + +H+ NLI VE LKA
Sbjct: 43 DFTSIPEDLYSTNEFNIWKRPRIIDFDSNTMPVIFQQIDIDHYVITGSNPEPVFRIFGINESGNSILALIHGFYPYFYVKSPENFKIGDCETFRDFLNELLKSKTKRHKEIGNLIINVELFLKA 166
BLAST of DNA polymerase vs. Planmine SMEST
Match: SMESG000033512.1 (SMESG000033512.1) HSP 1 Score: 513.842 bits (1322), Expect = 7.810e-173 Identity = 237/346 (68.50%), Postives = 293/346 (84.68%), Query Frame = 3
Query: 2418 MCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFDKMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELTKTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVLDNNIGIDTDYYLKNQLTNPLLRIFEPIFGKELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKSICAHCKPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSLHQEVLCSNRDCPIFYTRKKVQKELISQDEIMERLNQDLSW 3455
MCL V TV EA+ LGK+AA+ IS KFI+PIK+EFE VY PYL+++KKRYAG+ YTKPD +DKM+CKG+ETVRRD+CPLV NLLN+CL++LLI RDK +AL HAQSVIADL+CN+IDISQLIIS+EL KT++EYTSKQPHSELA K+ KRDP SAPQLGDRV YVITT G+++K YTKAEDP+YVL+N++ IDT+YYLKNQL NPLLRIFEPIFGK++ +R+LL+GEH+L+K K QSN G L KYTVIKPKC+ CKN+L+++EKS+C HC+ N IY RE +SLE +F RLWTECQRC+ +LH+EVLCSN DCPIF+ RK +QK LI Q+E +E+ +DL W
Sbjct: 1 MCLLNVETVSEAINLGKKAAEIISTKFISPIKMEFENVYLPYLIVNKKRYAGICYTKPDVYDKMNCKGIETVRRDSCPLVGNLLNSCLKRLLIDRDKESALQHAQSVIADLMCNKIDISQLIISRELNKTNKEYTSKQPHSELALKMFKRDPRSAPQLGDRVSYVITTHGIQNKAYTKAEDPLYVLENDLIIDTNYYLKNQLINPLLRIFEPIFGKDVTSRRLLYGEHMLTKSKPQSNTGPLFKYTVIKPKCVSCKNILQNNEKSLCLHCRDNASTIYLREITCLRSLEKKFCRLWTECQRCTENLHKEVLCSNHDCPIFFKRKAIQKSLIMQNETIEKFERDLEW 346
BLAST of DNA polymerase vs. Planmine SMEST
Match: SMESG000077868.1 (SMESG000077868.1) HSP 1 Score: 284.263 bits (726), Expect = 2.271e-78 Identity = 226/792 (28.54%), Postives = 374/792 (47.22%), Query Frame = 3
Query: 1236 HVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDL--QNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFV-----LPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLL---------KSKESIREFG----LTEDDYIK--------TPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIE--TDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVES------SFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFD-KMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELT-KTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVL---------DNNIGIDTD--------YYLKNQLTNPLLR----IFEPIFG--KELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKS--------ICAHC-KPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSL--HQEV--LCSNRDCPIFYTR 3386
H + +E EL++ + E DPDI+ G+ T YL+ R+ +N K + L R+ T++ S + ++H GR+ DL++++ + L SY+L + L+E+ +Q + N D T Y + + +R++ K+ ++ E AR+ G+ ++LSRG Q +V S +LR A ++ + + + +E T +EP G Y P+ LDF SLYPSIM+ +N CY T L S++ E G + ++ I+ +P G FV+ ++KG++ ++ +++ R K+ + I P + +LD RQL LK+ AN YG+T A GR+PC+ + S+ RE ++ T ++V S S + G KVIYGDTDSV + T EA LG A +++ P+KL+FEKV+ P LL +KKRY G+ Y PD K D KG+ETVRRDNC +V +L L +L S D N+ + + ++ I+I II+KE + + S P +A K+ K+DP + P G+RVPYVI D + + P +L NNI + + YY+ Q+ PL R I + +F ++ R +G + + +S Y C+ C + ++ ++ S +C +C + +L IY K K +E + +C C+ ++ H+ + C ++DCPIF+ R
Sbjct: 704 HFVRVASETELMDKIIELVWEFDPDILVGFETVRSSWGYLLERSFNINHKLYHGLSRLIIQN---TDAFSTKCSINSYKTYDLHCTGRMVLDLWIVIKHEITLNSYTLENCADEILKERVPYYTNQQLMAFYRSNTDRDTLMNFFFYRVLAN---IRILTKMNLISQISEFARIYGIEFYHVLSRGSQYRVESMMLRLAKPQNLIAISPNVSQRAQQKANECIPLT-LEPKSGLYWDPVVVLDFQSLYPSIMIGYNYCYATTLGKLDHIINVDSRQESYELGCSRMMLDNSSIRKVGSGVSISPNGVAFVRPEIQKGIISKMVEEILNTRIMVKKSMKIHAANKPLCK-LLDARQLGLKLIANVTYGYTAANFSGRMPCVEVGDSIVRKSRETLEETIKLVNSGGPNHVSKLDSEGGWAGCKVIYGDTDSVFVVMPNRTKDEAFVLGARIADAVTSVNPFPVKLKFEKVFLPCLLEAKKRYVGLSYESPDQIQPKFDAKGIETVRRDNCGIVGKILERTLNRLF-SSDINSVKRYVTQQLDQIMRGDINIFDFIIAKEYRGRGGYKANSSVPAVHIANKLVKKDPRAEPLNGERVPYVIIQGAPGDTLISCVRQPEEILFNTKMLKAYGNNIRLLNEQGCKLSYTYYITKQILPPLNRALNLIGQDVFSWYSKMPKRLKSYGNGYRGQCSSKLLNRTISSY-FQSQSCLICNSTVKSNQNSDSNSFSSVLCENCLRKGKLHIYLTAMKQLKDIEAYRKSILDKCFLCTNTVPTHRGIGPPCVSKDCPIFFDR 1485
BLAST of DNA polymerase vs. Planmine SMEST
Match: SMESG000077868.1 (SMESG000077868.1) HSP 1 Score: 284.263 bits (726), Expect = 2.415e-78 Identity = 226/792 (28.54%), Postives = 374/792 (47.22%), Query Frame = 3
Query: 1236 HVIPHKTEAELLEHWSNFIREIDPDIITGYNTQNFDLPYLINRANKLNVKGFSLLGRIKSMRSKITESQSQSKQMGRRINKNVHMPGRIHFDLYLILLRDHKLRSYSLNAVSFHFLEEQKEDVAHQIITDL--QNGDDRTRHRLAVYCLKDSDLVLRLMNKLMVVVNYVEMARVTGVPLSYLLSRGQQIKVLSQLLRKAAIEDFV-----LPDYQSKDGDEFTGATVIEPIKGFYDKPIATLDFASLYPSIMMAHNLCYTTLL---------KSKESIREFG----LTEDDYIK--------TPCGSYFVKSSVKKGLLPNILIQLIEARKKAKRELAIE--TDPFKRQVLDGRQLALKISANSVYGFTGAQ-RGRLPCLNISSSVTAFGREMIDFTKEMVES------SFNKANGYVHDAKVIYGDTDSVMCLFGVSTVVEAMALGKEAAQSISGKFIAPIKLEFEKVYYPYLLISKKRYAGMYYTKPDSFD-KMDCKGMETVRRDNCPLVANLLNTCLRKLLISRDKNAALSHAQSVIADLLCNRIDISQLIISKELT-KTDEEYTSKQPHSELAQKIKKRDPGSAPQLGDRVPYVITTLGVKDKIYTKAEDPIYVL---------DNNIGIDTD--------YYLKNQLTNPLLR----IFEPIFG--KELATRKLLHGEHVLSKFKQQSNVGALSKYTVIKPKCIGCKNVLRDDEKS--------ICAHC-KPNELAIYCRESKYNKSLEIRFSRLWTECQRCSGSL--HQEV--LCSNRDCPIFYTR 3386
H + +E EL++ + E DPDI+ G+ T YL+ R+ +N K + L R+ T++ S + ++H GR+ DL++++ + L SY+L + L+E+ +Q + N D T Y + + +R++ K+ ++ E AR+ G+ ++LSRG Q +V S +LR A ++ + + + +E T +EP G Y P+ LDF SLYPSIM+ +N CY T L S++ E G + ++ I+ +P G FV+ ++KG++ ++ +++ R K+ + I P + +LD RQL LK+ AN YG+T A GR+PC+ + S+ RE ++ T ++V S S + G KVIYGDTDSV + T EA LG A +++ P+KL+FEKV+ P LL +KKRY G+ Y PD K D KG+ETVRRDNC +V +L L +L S D N+ + + ++ I+I II+KE + + S P +A K+ K+DP + P G+RVPYVI D + + P +L NNI + + YY+ Q+ PL R I + +F ++ R +G + + +S Y C+ C + ++ ++ S +C +C + +L IY K K +E + +C C+ ++ H+ + C ++DCPIF+ R
Sbjct: 775 HFVRVASETELMDKIIELVWEFDPDILVGFETVRSSWGYLLERSFNINHKLYHGLSRLIIQN---TDAFSTKCSINSYKTYDLHCTGRMVLDLWIVIKHEITLNSYTLENCADEILKERVPYYTNQQLMAFYRSNTDRDTLMNFFFYRVLAN---IRILTKMNLISQISEFARIYGIEFYHVLSRGSQYRVESMMLRLAKPQNLIAISPNVSQRAQQKANECIPLT-LEPKSGLYWDPVVVLDFQSLYPSIMIGYNYCYATTLGKLDHIINVDSRQESYELGCSRMMLDNSSIRKVGSGVSISPNGVAFVRPEIQKGIISKMVEEILNTRIMVKKSMKIHAANKPLCK-LLDARQLGLKLIANVTYGYTAANFSGRMPCVEVGDSIVRKSRETLEETIKLVNSGGPNHVSKLDSEGGWAGCKVIYGDTDSVFVVMPNRTKDEAFVLGARIADAVTSVNPFPVKLKFEKVFLPCLLEAKKRYVGLSYESPDQIQPKFDAKGIETVRRDNCGIVGKILERTLNRLF-SSDINSVKRYVTQQLDQIMRGDINIFDFIIAKEYRGRGGYKANSSVPAVHIANKLVKKDPRAEPLNGERVPYVIIQGAPGDTLISCVRQPEEILFNTKMLKAYGNNIRLLNEQGCKLSYTYYITKQILPPLNRALNLIGQDVFSWYSKMPKRLKSYGNGYRGQCSSKLLNRTISSY-FQSQSCLICNSTVKSNQNSDSNSFSSVLCENCLRKGKLHIYLTAMKQLKDIEAYRKSILDKCFLCTNTVPTHRGIGPPCVSKDCPIFFDR 1556 The following BLAST results are available for this feature:
BLAST of DNA polymerase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of DNA polymerase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of DNA polymerase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 4
BLAST of DNA polymerase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of DNA polymerase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of DNA polymerase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of DNA polymerase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of DNA polymerase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of DNA polymerase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of DNA polymerase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of DNA polymerase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 3
BLAST of DNA polymerase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of DNA polymerase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of DNA polymerase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30004407 ID=SMED30004407|Name=DNA polymerase|organism=Schmidtea mediterranea sexual|type=transcript|length=3559bpback to top protein sequence of SMED30004407-orf-1 >SMED30004407-orf-1 ID=SMED30004407-orf-1|Name=SMED30004407-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=877bp MTIPHYGYHNLASFDTDIDFSVRFMVDSGLDGCSWIELPINTYTVRPQTEback to top protein sequence of SMED30004407-orf-2 >SMED30004407-orf-2 ID=SMED30004407-orf-2|Name=SMED30004407-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=185bp LFKSNLKKSKMSRRPNSFQKNKTYAPSSKISKFEVKNNDEDDVSMDEWNHback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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