SMED30004380

Overview


Name	SMED30004380
Smed ID	SMED30004380
Length (bp)	2850

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of SMED30004380 (SMED30004380) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30004380 (SMED30004380) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30004380 (SMED30004380) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30004380 (SMED30004380) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30004380

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
nervous system	SMED30004380	SMESG000007103.1	dd_Smed_v4_10719_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30004380	SMESG000007103.1	dd_Smed_v4_10719_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Alignments

SMED30004380 aligns in the following genomic locations:


Alignment Location	Alignment Score
v31.000100:207068..249530 +	13429

Homology

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BLAST of SMED30004380 vs. Ensembl Human
Match: CYLD (CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584])

HSP 1 Score: 71.633 bits (174), Expect = 5.329e-12
Identity = 77/364 (21.15%), Postives = 160/364 (43.96%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLI---SQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCK--------HPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++    + N    Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    K  CK        HP+ +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  417 YLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKI--KQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWD-WRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 770

[Close]

BLAST of SMED30004380 vs. Ensembl Human
Match: CYLD (CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584])

HSP 1 Score: 71.2478 bits (173), Expect = 6.833e-12
Identity = 77/364 (21.15%), Postives = 160/364 (43.96%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLI---SQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCK--------HPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++    + N    Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    K  CK        HP+ +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  602 YLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKI--KQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWD-WRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 955

[Close]

Query: 1824 FVESVIVALFAKSDNLDFLI---SQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCK--------HPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++    + N    Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    K  CK        HP+ +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  602 YLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKI--KQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWD-WRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 955

[Close]

BLAST of SMED30004380 vs. Ensembl Human
Match: CYLD (CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584])

HSP 1 Score: 71.2478 bits (173), Expect = 7.182e-12
Identity = 77/364 (21.15%), Postives = 160/364 (43.96%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLI---SQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCK--------HPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++    + N    Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    K  CK        HP+ +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  599 YLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKI--KQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWD-WRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 952

[Close]

Query: 1824 FVESVIVALFAKSDNLDFLI---SQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCK--------HPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++    + N    Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    K  CK        HP+ +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  599 YLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKI--KQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWD-WRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 952

[Close]

BLAST of SMED30004380 vs. Ensembl Celegans
Match: cyld-1 (CYLinDromatosis (Human disease gene) homolog [Source:UniProtKB/TrEMBL;Acc:H2L265])

HSP 1 Score: 67.781 bits (164), Expect = 3.760e-11
Identity = 57/233 (24.46%), Postives = 105/233 (45.06%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQ-VNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLF---------ELDEISTFI-STFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYI----TSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCKHPEAVKLPE 2477
            ++++ + A+F ++   DFL+ + +      +  +K+LA +I++PLR+  YV    +  L K   E+            + +EI  FI S   + E F+ LI     K     + + +D     D++    TS+ LL   M   ++ F K P  LI+Q  +  +    +  ++PL++I+I+  +      C  C + +   C  C     +  S   FC+K  C H   + LPE
Sbjct:  775 YLDATLYAMFVQTTCFDFLLEKSIKGSETAQQFQKILAHEIVFPLRKVHYVRADHVMKLRKLLAELMPHVTGLTNEEKDPEEILGFIFSKVFHAEPFIKLIGQNHAKDSQYLVPIVVD-----DWLGGAATSQHLLERHMRSAQVTFAKAPPVLIMQLPRYGQQKV-FDKILPLETIDITPFVAGAVPACSKCQACSEVYCPTCFLTRRVFYSEVIFCRK--CFHHTHL-LPE 998

[Close]

BLAST of SMED30004380 vs. Ensembl Celegans
Match: cyld-1 (CYLinDromatosis (Human disease gene) homolog [Source:UniProtKB/TrEMBL;Acc:H2L265])

HSP 1 Score: 67.3958 bits (163), Expect = 4.003e-11
Identity = 57/233 (24.46%), Postives = 105/233 (45.06%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQ-VNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLF---------ELDEISTFI-STFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYI----TSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCKHPEAVKLPE 2477
            ++++ + A+F ++   DFL+ + +      +  +K+LA +I++PLR+  YV    +  L K   E+            + +EI  FI S   + E F+ LI     K     + + +D     D++    TS+ LL   M   ++ F K P  LI+Q  +  +    +  ++PL++I+I+  +      C  C + +   C  C     +  S   FC+K  C H   + LPE
Sbjct:  465 YLDATLYAMFVQTTCFDFLLEKSIKGSETAQQFQKILAHEIVFPLRKVHYVRADHVMKLRKLLAELMPHVTGLTNEEKDPEEILGFIFSKVFHAEPFIKLIGQNHAKDSQYLVPIVVD-----DWLGGAATSQHLLERHMRSAQVTFAKAPPVLIMQLPRYGQQKV-FDKILPLETIDITPFVAGAVPACSKCQACSEVYCPTCFLTRRVFYSEVIFCRK--CFHHTHL-LPE 688

[Close]

BLAST of SMED30004380 vs. Ensembl Celegans
Match: cyld-1 (CYLinDromatosis (Human disease gene) homolog [Source:UniProtKB/TrEMBL;Acc:H2L265])

HSP 1 Score: 67.3958 bits (163), Expect = 4.166e-11
Identity = 57/233 (24.46%), Postives = 105/233 (45.06%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQ-VNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLF---------ELDEISTFI-STFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYI----TSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCKHPEAVKLPE 2477
            ++++ + A+F ++   DFL+ + +      +  +K+LA +I++PLR+  YV    +  L K   E+            + +EI  FI S   + E F+ LI     K     + + +D     D++    TS+ LL   M   ++ F K P  LI+Q  +  +    +  ++PL++I+I+  +      C  C + +   C  C     +  S   FC+K  C H   + LPE
Sbjct:  523 YLDATLYAMFVQTTCFDFLLEKSIKGSETAQQFQKILAHEIVFPLRKVHYVRADHVMKLRKLLAELMPHVTGLTNEEKDPEEILGFIFSKVFHAEPFIKLIGQNHAKDSQYLVPIVVD-----DWLGGAATSQHLLERHMRSAQVTFAKAPPVLIMQLPRYGQQKV-FDKILPLETIDITPFVAGAVPACSKCQACSEVYCPTCFLTRRVFYSEVIFCRK--CFHHTHL-LPE 746

[Close]

BLAST of SMED30004380 vs. Ensembl Fly
Match: CYLD (gene:FBgn0032210 transcript:FBtr0080070)

HSP 1 Score: 69.3218 bits (168), Expect = 1.021e-11
Identity = 55/217 (25.35%), Postives = 108/217 (49.77%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ----YEAIRKVLAWKIIYPLREFGYVS-------HHMLEDLAKCFGEINLFELDE---ISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFC 2432
            ++++ + ++F  +   D ++ +  P PQ    Y  ++KVL  +I+ PLR+  +V          +L+ L+   G +   E D    +++ +S     E FL L S +     S   +LF++  E+L   + +QL   S   + I  +++PSC IIQ  +  K+   Y  ++P + ++++ +I N  ++C  C  +A ++C  C   G+L+  SG  C
Sbjct:  285 YLDATLFSMFTFTSVFDSILYR-RPGPQDIRNYSEVQKVLRDEIVNPLRKNVFVRSDRVMKLRELLDQLSSVSG-LTCEEKDPEEFLNSLLSQIMRVEPFLKLSSGQD----SYFYQLFVEKDEKLTLPSVQQLFEQSFHSSDIKLKEVPSCFIIQMPRFGKNYKMYPRILPSQVLDVTDIIENSPRQCSLCGKLAEYECRDC--FGSLQAGSGLEC 493

[Close]

BLAST of SMED30004380 vs. Ensembl Fly
Match: CYLD (gene:FBgn0032210 transcript:FBtr0080071)

HSP 1 Score: 69.3218 bits (168), Expect = 1.021e-11
Identity = 55/217 (25.35%), Postives = 108/217 (49.77%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ----YEAIRKVLAWKIIYPLREFGYVS-------HHMLEDLAKCFGEINLFELDE---ISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFC 2432
            ++++ + ++F  +   D ++ +  P PQ    Y  ++KVL  +I+ PLR+  +V          +L+ L+   G +   E D    +++ +S     E FL L S +     S   +LF++  E+L   + +QL   S   + I  +++PSC IIQ  +  K+   Y  ++P + ++++ +I N  ++C  C  +A ++C  C   G+L+  SG  C
Sbjct:  285 YLDATLFSMFTFTSVFDSILYR-RPGPQDIRNYSEVQKVLRDEIVNPLRKNVFVRSDRVMKLRELLDQLSSVSG-LTCEEKDPEEFLNSLLSQIMRVEPFLKLSSGQD----SYFYQLFVEKDEKLTLPSVQQLFEQSFHSSDIKLKEVPSCFIIQMPRFGKNYKMYPRILPSQVLDVTDIIENSPRQCSLCGKLAEYECRDC--FGSLQAGSGLEC 493

[Close]

BLAST of SMED30004380 vs. Ensembl Fly
Match: CYLD (gene:FBgn0032210 transcript:FBtr0080072)

HSP 1 Score: 68.5514 bits (166), Expect = 1.576e-11
Identity = 73/322 (22.67%), Postives = 148/322 (45.96%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ----YEAIRKVLAWKIIYPLREFGYVS-------HHMLEDLAKCFGEINLFELDE---ISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGF----FCQK-------------HMCKHPEAVKLPEFNLWNK----SKIFLNLSSIIYKTKLYYGALVKQ-KGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFL 2666
            ++++ + ++F  +   D ++ +  P PQ    Y  ++KVL  +I+ PLR+  +V          +L+ L+   G +   E D    +++ +S     E FL L S +     S   +LF++  E+L   + +QL   S   + I  +++PSC IIQ  +  K+   Y  ++P + ++++ +I N  ++C  C  +A ++C  C   G+L+  SG     FC K             H+ K   + K  EF +  +     ++++ L +++     +Y A VK   G +  W  +     +  E++G     ++   E++ +L
Sbjct:  197 YLDATLFSMFTFTSVFDSILYR-RPGPQDIRNYSEVQKVLRDEIVNPLRKNVFVRSDRVMKLRELLDQLSSVSG-LTCEEKDPEEFLNSLLSQIMRVEPFLKLSSGQD----SYFYQLFVEKDEKLTLPSVQQLFEQSFHSSDIKLKEVPSCFIIQMPRFGKNYKMYPRILPSQVLDVTDIIENSPRQCSLCGKLAEYECRDC--FGSLQAGSGLECTAFCPKCLKTFHSHIKRTNHVSKKIYSPK--EFKIMAEHMVVPRLYMELFAVVCIETSHYVAFVKSGSGPDAPWCFFDSMADRKGEQNGYNIPEITCVPELTQWL 508

[Close]

BLAST of SMED30004380 vs. Ensembl Zebrafish
Match: cyldl (cylindromatosis (turban tumor syndrome), like [Source:ZFIN;Acc:ZDB-GENE-131127-190])

HSP 1 Score: 76.6406 bits (187), Expect = 8.618e-14
Identity = 78/321 (24.30%), Postives = 142/321 (44.24%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLD-FLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE---------------RKKSMSIQL-KLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGF--FCQK--------HMCKH--PEAVKLPEFNLWNKSKIF----LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQL 2672
            +++S + ++F+ S  LD  L   +NP+ +   I+ +L   I+ PLR+ G+VS   + +L K      L + +   T+ +   + E FLSLI  E               R K  S    ++F+D    L   T +QLL  S   N +   ++P+CLI+   +  KS   +  +IP   ++I+ L+ +  ++C+ C  +A  +C  C    AL   +GF  FC K           +H  P ++ LP+   ++ S       L L +++     +Y + VK    +  W      + +V E +G     +    E+  +L +
Sbjct:  411 YMDSALFSVFSCSSVLDSLLFKSINPEDK--TIQDILLKNIVNPLRKQGFVSARCVMNLRK-----QLQKREHCPTYTTDEKDPEEFLSLIMQEILFLDPLLSLCQSGSRHKVQSCYYYQIFMDYNHHLVLPTVQQLLEHSFYSNSLKLAEVPACLILTMPRSGKSFKMFPKIIPSTELDITGLLADSPQQCVSCGLLANEECAECFR-DALFSDTGFKYFCTKCSTQVHSHQQRRHHTPSSLHLPQGFSYSDSLTPPPEKLELFAVLCIETSHYVSFVKHGPRDTDWIFFDSMADRVGESNGYNIPEVRACPEVGQYLHM 723

[Close]

Query: 1824 FVESVIVALFAKSDNLD-FLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE---------------RKKSMSIQL-KLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGF--FCQK--------HMCKH--PEAVKLPEFNLWNKSKIF----LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQL 2672
            +++S + ++F+ S  LD  L   +NP+ +   I+ +L   I+ PLR+ G+VS   + +L K      L + +   T+ +   + E FLSLI  E               R K  S    ++F+D    L   T +QLL  S   N +   ++P+CLI+   +  KS   +  +IP   ++I+ L+ +  ++C+ C  +A  +C  C    AL   +GF  FC K           +H  P ++ LP+   ++ S       L L +++     +Y + VK    +  W      + +V E +G     +    E+  +L +
Sbjct:  411 YMDSALFSVFSCSSVLDSLLFKSINPEDK--TIQDILLKNIVNPLRKQGFVSARCVMNLRK-----QLQKREHCPTYTTDEKDPEEFLSLIMQEILFLDPLLSLCQSGSRHKVQSCYYYQIFMDYNHHLVLPTVQQLLEHSFYSNSLKLAEVPACLILTMPRSGKSFKMFPKIIPSTELDITGLLADSPQQCVSCGLLANEECAECFR-DALFSDTGFKYFCTKCSTQVHSHQQRRHHTPSSLHLPQGFSYSDSLTPPPEKLELFAVLCIETSHYVSFVKHGPRDTDWIFFDSMADRVGESNGYNIPEVRACPEVGQYLHM 723

[Close]

BLAST of SMED30004380 vs. Ensembl Zebrafish
Match: cylda (cylindromatosis (turban tumor syndrome), a [Source:ZFIN;Acc:ZDB-GENE-061108-2])

HSP 1 Score: 75.0998 bits (183), Expect = 3.024e-13
Identity = 80/367 (21.80%), Postives = 168/367 (45.78%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFCQK-----HMCKHPEA-----VKL--PE---FNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y+  +++L  +I+ PLR  GYV    +  L +      L +++  S F S   + E FL+++ +           R     +Q     ++F+D K+++   TS+QLL  S I + + F + PSCLIIQ  +  K    +  + P   ++I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC+K     H+  HP       VKL  P+    ++W +       + L +++     +Y A VK   +++ W      + +   ++G     +S   E+  +L++  +E+      +   + + ++ + +  +Y +  ++ Y
Sbjct:  558 YLDSTLFCLFSFSSVLDTVL--LRPRSKTDVEYYKETQELLRTEIVNPLRIHGYVCATKIMKLRRI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLRLRSAGQKVQDCYFYQIFMDKKDKVMVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLDDTPRECRICGGLALYECRECYEDYDITPGKIKQ----FCEKCNTQVHL--HPRRKIHRYVKLSVPKELHESVWRQGSYPHQQMELFAVLCIETSHYVAFVKYGSADSAWLFFDSMADRDGGQNGFNIPQVSRCPEVGEYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 911

[Close]

BLAST of SMED30004380 vs. Ensembl Zebrafish
Match: cylda (cylindromatosis (turban tumor syndrome), a [Source:ZFIN;Acc:ZDB-GENE-061108-2])

HSP 1 Score: 75.0998 bits (183), Expect = 3.195e-13
Identity = 80/367 (21.80%), Postives = 168/367 (45.78%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFCQK-----HMCKHPEA-----VKL--PE---FNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y+  +++L  +I+ PLR  GYV    +  L +      L +++  S F S   + E FL+++ +           R     +Q     ++F+D K+++   TS+QLL  S I + + F + PSCLIIQ  +  K    +  + P   ++I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC+K     H+  HP       VKL  P+    ++W +       + L +++     +Y A VK   +++ W      + +   ++G     +S   E+  +L++  +E+      +   + + ++ + +  +Y +  ++ Y
Sbjct:  597 YLDSTLFCLFSFSSVLDTVL--LRPRSKTDVEYYKETQELLRTEIVNPLRIHGYVCATKIMKLRRI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLRLRSAGQKVQDCYFYQIFMDKKDKVMVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLDDTPRECRICGGLALYECRECYEDYDITPGKIKQ----FCEKCNTQVHL--HPRRKIHRYVKLSVPKELHESVWRQGSYPHQQMELFAVLCIETSHYVAFVKYGSADSAWLFFDSMADRDGGQNGFNIPQVSRCPEVGEYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 950

[Close]

BLAST of SMED30004380 vs. Ensembl Zebrafish
Match: cylda (cylindromatosis (turban tumor syndrome), a [Source:ZFIN;Acc:ZDB-GENE-061108-2])

HSP 1 Score: 75.0998 bits (183), Expect = 3.195e-13
Identity = 80/367 (21.80%), Postives = 168/367 (45.78%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFCQK-----HMCKHPEA-----VKL--PE---FNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y+  +++L  +I+ PLR  GYV    +  L +      L +++  S F S   + E FL+++ +           R     +Q     ++F+D K+++   TS+QLL  S I + + F + PSCLIIQ  +  K    +  + P   ++I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC+K     H+  HP       VKL  P+    ++W +       + L +++     +Y A VK   +++ W      + +   ++G     +S   E+  +L++  +E+      +   + + ++ + +  +Y +  ++ Y
Sbjct:  597 YLDSTLFCLFSFSSVLDTVL--LRPRSKTDVEYYKETQELLRTEIVNPLRIHGYVCATKIMKLRRI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLRLRSAGQKVQDCYFYQIFMDKKDKVMVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLDDTPRECRICGGLALYECRECYEDYDITPGKIKQ----FCEKCNTQVHL--HPRRKIHRYVKLSVPKELHESVWRQGSYPHQQMELFAVLCIETSHYVAFVKYGSADSAWLFFDSMADRDGGQNGFNIPQVSRCPEVGEYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 950

[Close]

BLAST of SMED30004380 vs. Ensembl Xenopus
Match: tril (TLR4 interactor with leucine-rich repeats [Source:Xenbase;Acc:XB-GENE-6050227])

HSP 1 Score: 70.0922 bits (170), Expect = 1.656e-11
Identity = 78/368 (21.20%), Postives = 163/368 (44.29%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFC-----QKHMCKHPE-----------AVKLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y   + +L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F+D  E +   T +QLL  S I + + F + PSCLI+Q  +  K    +  + P   + I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC     Q H+  HP+             +LP+++ W    I    ++L +++     +Y A VK    ++ W  +     +   ++G     ++   E+  +L+++ +E+    S +     + ++ + +  +Y +  ++ Y
Sbjct:  539 YLDSTLFCLFSFSSVLDSVL--LRPKEKTDVEYYSETQALLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKIRSAGQKVQDCYFYQIFMDKNENVGVPTIQQLLEWSFINSSLKFAEAPSCLIVQMPRFGKDFKMFNKIFPSLDLNITDLLEDTPRQCRICGGLAMYECRECYDDPDITAGKIKQ----FCKICNTQVHL--HPKRQHHKFNPVSLPKELPDWD-WRHGCIPYQKMDLFAVLCIETSHYVAFVKYGRDDSSWVFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEELHALDSRNIQGCARRLLCDAYMCMYQSPTMSLY 892

[Close]

BLAST of SMED30004380 vs. Ensembl Xenopus
Match: tril (TLR4 interactor with leucine-rich repeats [Source:Xenbase;Acc:XB-GENE-6050227])

HSP 1 Score: 69.707 bits (169), Expect = 1.891e-11
Identity = 78/368 (21.20%), Postives = 163/368 (44.29%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFC-----QKHMCKHPE-----------AVKLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y   + +L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F+D  E +   T +QLL  S I + + F + PSCLI+Q  +  K    +  + P   + I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC     Q H+  HP+             +LP+++ W    I    ++L +++     +Y A VK    ++ W  +     +   ++G     ++   E+  +L+++ +E+    S +     + ++ + +  +Y +  ++ Y
Sbjct:  621 YLDSTLFCLFSFSSVLDSVL--LRPKEKTDVEYYSETQALLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKIRSAGQKVQDCYFYQIFMDKNENVGVPTIQQLLEWSFINSSLKFAEAPSCLIVQMPRFGKDFKMFNKIFPSLDLNITDLLEDTPRQCRICGGLAMYECRECYDDPDITAGKIKQ----FCKICNTQVHL--HPKRQHHKFNPVSLPKELPDWD-WRHGCIPYQKMDLFAVLCIETSHYVAFVKYGRDDSSWVFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEELHALDSRNIQGCARRLLCDAYMCMYQSPTMSLY 974

[Close]

BLAST of SMED30004380 vs. Ensembl Xenopus
Match: tril (TLR4 interactor with leucine-rich repeats [Source:Xenbase;Acc:XB-GENE-6050227])

HSP 1 Score: 69.707 bits (169), Expect = 1.991e-11
Identity = 78/368 (21.20%), Postives = 163/368 (44.29%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFC-----QKHMCKHPE-----------AVKLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y   + +L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F+D  E +   T +QLL  S I + + F + PSCLI+Q  +  K    +  + P   + I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC     Q H+  HP+             +LP+++ W    I    ++L +++     +Y A VK    ++ W  +     +   ++G     ++   E+  +L+++ +E+    S +     + ++ + +  +Y +  ++ Y
Sbjct:  603 YLDSTLFCLFSFSSVLDSVL--LRPKEKTDVEYYSETQALLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKIRSAGQKVQDCYFYQIFMDKNENVGVPTIQQLLEWSFINSSLKFAEAPSCLIVQMPRFGKDFKMFNKIFPSLDLNITDLLEDTPRQCRICGGLAMYECRECYDDPDITAGKIKQ----FCKICNTQVHL--HPKRQHHKFNPVSLPKELPDWD-WRHGCIPYQKMDLFAVLCIETSHYVAFVKYGRDDSSWVFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEELHALDSRNIQGCARRLLCDAYMCMYQSPTMSLY 956

[Close]

BLAST of SMED30004380 vs. Ensembl Xenopus
Match: tril (TLR4 interactor with leucine-rich repeats [Source:Xenbase;Acc:XB-GENE-6050227])

HSP 1 Score: 69.3218 bits (168), Expect = 2.292e-11
Identity = 78/368 (21.20%), Postives = 163/368 (44.29%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFC-----QKHMCKHPE-----------AVKLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y   + +L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F+D  E +   T +QLL  S I + + F + PSCLI+Q  +  K    +  + P   + I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC     Q H+  HP+             +LP+++ W    I    ++L +++     +Y A VK    ++ W  +     +   ++G     ++   E+  +L+++ +E+    S +     + ++ + +  +Y +  ++ Y
Sbjct:  418 YLDSTLFCLFSFSSVLDSVL--LRPKEKTDVEYYSETQALLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKIRSAGQKVQDCYFYQIFMDKNENVGVPTIQQLLEWSFINSSLKFAEAPSCLIVQMPRFGKDFKMFNKIFPSLDLNITDLLEDTPRQCRICGGLAMYECRECYDDPDITAGKIKQ----FCKICNTQVHL--HPKRQHHKFNPVSLPKELPDWD-WRHGCIPYQKMDLFAVLCIETSHYVAFVKYGRDDSSWVFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEELHALDSRNIQGCARRLLCDAYMCMYQSPTMSLY 771

[Close]

BLAST of SMED30004380 vs. Ensembl Xenopus
Match: tril (TLR4 interactor with leucine-rich repeats [Source:Xenbase;Acc:XB-GENE-6050227])

HSP 1 Score: 56.6102 bits (135), Expect = 2.196e-7
Identity = 73/354 (20.62%), Postives = 160/354 (45.20%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFC-----QKHMCKHPE-----------AVKLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y   + +L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +   +++  +L +  D+   L ++T    LNI ++       + PSCLI+Q  +  K    +  + P   + I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC     Q H+  HP+             +LP+++ W    I    ++L +++     +Y A VK    ++ W  +     +   ++G     ++   E+  +L+++ +E+    S +     + ++ + +  +Y +  ++ Y
Sbjct:  620 YLDSTLFCLFSFSSVLDSVL--LRPKEKTDVEYYSETQALLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRNIESKLSV-TDICAGLLWVT----LNIELVC------EAPSCLIVQMPRFGKDFKMFNKIFPSLDLNITDLLEDTPRQCRICGGLAMYECRECYDDPDITAGKIKQ----FCKICNTQVHL--HPKRQHHKFNPVSLPKELPDWD-WRHGCIPYQKMDLFAVLCIETSHYVAFVKYGRDDSSWVFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEELHALDSRNIQGCARRLLCDAYMCMYQSPTMSLY 948

[Close]

BLAST of SMED30004380 vs. Ensembl Mouse
Match: Cyld (CYLD lysine 63 deubiquitinase [Source:MGI Symbol;Acc:MGI:1921506])

HSP 1 Score: 72.4034 bits (176), Expect = 2.009e-12
Identity = 77/364 (21.15%), Postives = 160/364 (43.96%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLI---SQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCK--------HPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++    + N    Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ ++          R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    K  CK        HP  +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  416 YLDSTLFCLFAFSSALDTVLLRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKI--KQFCKTCSTQVHLHPRRLNHSYHPVSLPKDLPDWD-WRHGCIPCQKMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 769

[Close]

BLAST of SMED30004380 vs. Ensembl Mouse
Match: Cyld (CYLD lysine 63 deubiquitinase [Source:MGI Symbol;Acc:MGI:1921506])

HSP 1 Score: 72.4034 bits (176), Expect = 2.454e-12
Identity = 78/366 (21.31%), Postives = 164/366 (44.81%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSG---FFC-----QKHMCKHPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++  + P+ +     Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ ++          R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    FC     Q H+  HP  +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  601 YLDSTLFCLFAFSSALDTVL--LRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKIKQFCKTCSTQVHL--HPRRLNHSYHPVSLPKDLPDWD-WRHGCIPCQKMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 954

[Close]

BLAST of SMED30004380 vs. Ensembl Mouse
Match: Cyld (CYLD lysine 63 deubiquitinase [Source:MGI Symbol;Acc:MGI:1921506])

HSP 1 Score: 72.4034 bits (176), Expect = 2.454e-12
Identity = 78/366 (21.31%), Postives = 164/366 (44.81%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSG---FFC-----QKHMCKHPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++  + P+ +     Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ ++          R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    FC     Q H+  HP  +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  601 YLDSTLFCLFAFSSALDTVL--LRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKIKQFCKTCSTQVHL--HPRRLNHSYHPVSLPKDLPDWD-WRHGCIPCQKMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 954

[Close]

BLAST of SMED30004380 vs. Ensembl Mouse
Match: Cyld (CYLD lysine 63 deubiquitinase [Source:MGI Symbol;Acc:MGI:1921506])

HSP 1 Score: 72.4034 bits (176), Expect = 2.557e-12
Identity = 78/366 (21.31%), Postives = 164/366 (44.81%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSG---FFC-----QKHMCKHPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++  + P+ +     Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ ++          R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    FC     Q H+  HP  +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  598 YLDSTLFCLFAFSSALDTVL--LRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKIKQFCKTCSTQVHL--HPRRLNHSYHPVSLPKDLPDWD-WRHGCIPCQKMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 951

[Close]

BLAST of SMED30004380 vs. Ensembl Mouse
Match: Cyld (CYLD lysine 63 deubiquitinase [Source:MGI Symbol;Acc:MGI:1921506])

HSP 1 Score: 72.4034 bits (176), Expect = 2.557e-12
Identity = 78/366 (21.31%), Postives = 164/366 (44.81%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSG---FFC-----QKHMCKHPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++  + P+ +     Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ ++          R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    FC     Q H+  HP  +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  598 YLDSTLFCLFAFSSALDTVL--LRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKIKQFCKTCSTQVHL--HPRRLNHSYHPVSLPKDLPDWD-WRHGCIPCQKMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 951

[Close]

BLAST of SMED30004380 vs. UniProt/SwissProt
Match: sp|Q1RMU2|CYLD_BOVIN (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Bos taurus OX=9913 GN=CYLD PE=2 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 5.760e-12
Identity = 79/364 (21.70%), Postives = 162/364 (44.51%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLI---SQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSG---FFC-----QKHMCKHPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++    + N    Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    FC     Q H+  HP+ +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ D++    S       + ++ + +  +Y +  ++ Y
Sbjct:  599 YLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLECSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKIKQFCKTCNAQVHL--HPKRLNHKYNPVSLPKDLPDWD-WRHGCIPCQKMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLDDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 952

[Close]

BLAST of SMED30004380 vs. UniProt/SwissProt
Match: sp|Q66H62|CYLD_RAT (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Rattus norvegicus OX=10116 GN=Cyld PE=1 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 1.240e-11
Identity = 78/364 (21.43%), Postives = 162/364 (44.51%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLI---SQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSG---FFC-----QKHMCKHPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++    + N    Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ ++          R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    FC     Q H+  HP  +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  599 YLDSTLFCLFAFSSALDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKIKQFCKTCSTQVHL--HPRRLNHTYHPVSLPKDLPDWD-WRHGCIPCQKMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 952

[Close]

BLAST of SMED30004380 vs. UniProt/SwissProt
Match: sp|Q80TQ2|CYLD_MOUSE (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Mus musculus OX=10090 GN=Cyld PE=1 SV=2)

HSP 1 Score: 72.4034 bits (176), Expect = 1.789e-11
Identity = 78/366 (21.31%), Postives = 164/366 (44.81%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSG---FFC-----QKHMCKHPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++  + P+ +     Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ ++          R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    FC     Q H+  HP  +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  598 YLDSTLFCLFAFSSALDTVL--LRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKIKQFCKTCSTQVHL--HPRRLNHSYHPVSLPKDLPDWD-WRHGCIPCQKMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 951

[Close]

BLAST of SMED30004380 vs. UniProt/SwissProt
Match: sp|Q5RED8|CYLD_PONAB (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Pongo abelii OX=9601 GN=CYLD PE=2 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 3.172e-11
Identity = 78/364 (21.43%), Postives = 162/364 (44.51%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLI---SQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSG---FFC-----QKHMCKHPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++    + N    Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    FC     Q H+  HP+ +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  602 YLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKIKQFCKTCNTQVHL--HPKRLNHKYNPVSLPKDLPDWD-WRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 955

[Close]

BLAST of SMED30004380 vs. UniProt/SwissProt
Match: sp|Q9NQC7|CYLD_HUMAN (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Homo sapiens OX=9606 GN=CYLD PE=1 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 3.282e-11
Identity = 77/364 (21.15%), Postives = 160/364 (43.96%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLI---SQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCK--------HPEAV-----------KLPEFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LFA S  LD ++    + N    Y   +++L  +I+ PLR +GYV    +  L K      L +++  S F S   + E FL+++ +           R     +Q     ++F++  E++   T +QLL  S I + + F + PSCLIIQ  +  K    ++ + P   + I+ L+ +  ++C  C  +A ++C  C      +IS+G    K  CK        HP+ +            LP+++ W    I    + L +++     +Y A VK    ++ W      + +   ++G     ++   E+  +L+++ +++    S       + ++ + +  +Y +  ++ Y
Sbjct:  602 YLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYD--DPDISAGKI--KQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWD-WRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 955

[Close]

BLAST of SMED30004380 vs. TrEMBL
Match: F4WWF9 (Putative ubiquitin carboxyl-terminal hydrolase CYLD OS=Acromyrmex echinatior OX=103372 GN=G5I_10276 PE=4 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 5.700e-15
Identity = 89/384 (23.18%), Postives = 175/384 (45.57%), Query Frame = 3

Query: 1698 VIGKNKIGNSKKSQISTYLQLAISKYQLKI---KTRILENSSKLNFVESVIVALFAKS---DNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVS-------HHMLEDLAKCFGEINLFELDE--ISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFC----------QKHMCKHPEAVKLP-EFNLWNK----SKIFLNLSSIIYKTKLYYGALVK-QKGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFLQ------LNEDEMKQHISYHDMEFL 2723
            +I  +  GN + S I+  ++    K  L+    K R ++      ++++ + ++F  +   DNL F        PQYE +++VL  +I+ PLR+  +V          +LE L+   G  +  +  E  +++ ++   N E FL L S +     +   +LF++  + L+  T +QLL  S + + I  +++PSCLIIQ  +  KS   Y+ + P   ++++ +I +  ++C  C  +A F+C  C     + + S  FC          ++     P+ + +P EF +  +     +++L LS+++     +Y + VK   GSE  W  +     +  E++G     +    +  Y+L       L E +  +H+  H    L
Sbjct:  390 LINNDNFGNMESSVITGIVRPISVKGDLESICGKYRGIQGHHNSCYLDATLFSMFTFTSVFDNLLFRPPNEKDCPQYEEVQRVLREEIVNPLRKNMFVRADRVMKLRTLLEKLSSVSGLTSEEKDPEEFLTSLVAQILNAEPFLKLSSGQD----AYHYQLFVEKDDHLNLPTVQQLLEQSFLTSNIRLKEVPSCLIIQMPRFGKSFKMYQKIQPTLLLDVTDIIEDSPRQCTVCGKLAEFECKECYGQCGVGLESIAFCLQCLEKVHRHERRTNHEPKKLNVPMEFTILQEHCPVPRLYLELSAVVCIETSHYVSFVKCGPGSEAPWCFFDSMADRKGEQNGYNIPEMVPCPDFPYWLSEEGGTYLTELKDDRHLPEHAKRLL 769

[Close]

BLAST of SMED30004380 vs. TrEMBL
Match: A0A158NKM7 (USP domain-containing protein OS=Atta cephalotes OX=12957 GN=105621225 PE=4 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 6.476e-15
Identity = 89/384 (23.18%), Postives = 175/384 (45.57%), Query Frame = 3

Query: 1698 VIGKNKIGNSKKSQISTYLQLAISKYQLKI---KTRILENSSKLNFVESVIVALFAKS---DNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVS-------HHMLEDLAKCFGEINLFELDE--ISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFC----------QKHMCKHPEAVKLP-EFNLWNK----SKIFLNLSSIIYKTKLYYGALVK-QKGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFLQ------LNEDEMKQHISYHDMEFL 2723
            +I  +  GN + S I+  ++    K  L+    K R ++      ++++ + ++F  +   DNL F        PQYE +++VL  +I+ PLR+  +V          +LE L+   G  +  +  E  +++ ++   N E FL L S +     +   +LF++  + L+  T +QLL  S + + I  +++PSCLIIQ  +  KS   Y+ + P   ++++ +I +  ++C  C  +A F+C  C     + + S  FC          ++     P+ + +P EF +  +     +++L LS+++     +Y + VK   GSE  W  +     +  E++G     +    +  Y+L       L E +  +H+  H    L
Sbjct:  389 LINNDNFGNMESSVITGIVRPISVKGDLESICGKYRGIQGHHNSCYLDATLFSMFTFTSVFDNLLFRPPNEKDCPQYEEVQRVLREEIVNPLRKNMFVRADRVMKLRTLLEKLSSVSGLTSEEKDPEEFLTSLVAQILNAEPFLKLSSGQD----AYHYQLFVEKDDHLNLPTVQQLLEQSFLTSNIRLKEVPSCLIIQMPRFGKSFKMYQKIQPTLLLDVTDIIEDSPRQCTVCGKLAEFECKECYGQCGVGLESIAFCLQCLEKVHRHERRTNHEPKKLNVPMEFTILQEHCPVPRLYLELSAVVCIETSHYVSFVKCGPGSEAPWCFFDSMADRKGEQNGYNIPEMVPCPDFPYWLSEEGGTYLTELKDDRHLPEHAKRLL 768

[Close]

BLAST of SMED30004380 vs. TrEMBL
Match: A0A195DG65 (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Trachymyrmex cornetzi OX=471704 GN=ALC57_16025 PE=4 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 6.999e-15
Identity = 89/384 (23.18%), Postives = 175/384 (45.57%), Query Frame = 3

Query: 1698 VIGKNKIGNSKKSQISTYLQLAISKYQLKI---KTRILENSSKLNFVESVIVALFAKS---DNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVS-------HHMLEDLAKCFGEINLFELDE--ISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFC----------QKHMCKHPEAVKLP-EFNLWNK----SKIFLNLSSIIYKTKLYYGALVK-QKGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFLQ------LNEDEMKQHISYHDMEFL 2723
            +I  +  GN + S I+  ++    K  L+    K R ++      ++++ + ++F  +   DNL F        PQYE +++VL  +I+ PLR+  +V          +LE L+   G  +  +  E  +++ ++   N E FL L S +     +   +LF++  + L+  T +QLL  S + + I  +++PSCLIIQ  +  KS   Y+ + P   ++++ +I +  ++C  C  +A F+C  C     + + S  FC          ++     P+ + +P EF +  +     +++L LS+++     +Y + VK   GSE  W  +     +  E++G     +    +  Y+L       L E +  +H+  H    L
Sbjct:  427 LINNDNFGNMESSVITGIVRPISVKGDLESICGKYRGIQGHHNSCYLDATLFSMFTFTSVFDNLLFRPPNEKDCPQYEEVQRVLREEIVNPLRKNMFVRADRVMKLRTLLEKLSSVSGLTSEEKDPEEFLTSLVAQILNAEPFLKLSSGQD----AYHYQLFVEKDDHLNLPTVQQLLEQSFLTSNIRLKEVPSCLIIQMPRFGKSFKMYQKIQPTLLLDVTDIIEDSPRQCTVCGKLAEFECKECYGQCGVGLESIAFCLQCLEKVHCHERRTNHEPKKLNVPMEFTILQEHCPVPRLYLELSAVVCIETSHYVSFVKCGPGSEAPWCFFDSMADRKGEQNGYNIPEMVPCPDFPYWLSEEGGTYLTELKDDRHLPEHAKRLL 806

[Close]

BLAST of SMED30004380 vs. TrEMBL
Match: A0A0L7R5H6 (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Habropoda laboriosa OX=597456 GN=WH47_01028 PE=4 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 8.572e-15
Identity = 87/368 (23.64%), Postives = 166/368 (45.11%), Query Frame = 3

Query: 1674 ASKKNPVEVIGKNKIGNSKKSQISTYLQLAISKYQLKI---KTRILENSSKLNFVESVIVALFAKS---DNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVS-------HHMLEDLAKCFGEINLFELDE---ISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFC----------QKHMCKHPEAVKLP-EFNLWNK----SKIFLNLSSIIYKTKLYYGALVK-QKGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFL 2666
            A   +P   I  +  GN + S I   ++    K  L+    K R ++      ++++ + ++F  +   DNL F        PQYE +++VL  +I+ PLR+  +V          +LE L+   G +   E D    +++ ++   N E FL L S +     +   +LF++  + L+  T +QLL  S + + I  +++PSCLIIQ  +  KS   Y+ + P   ++++ +I +  ++C  C  +A F+C  C       + S  FC          ++     P+ + +P EF +  +     +++L LS+++     +Y   VK   GSE  W  +     +  E++G     +    +  Y+L
Sbjct:  140 AKIDDPTTSISTDNFGNMESSVIVGMVRPISVKGNLESICGKYRGIQGHHNSCYLDATLFSMFTFTSVFDNLLFRPPNEKDCPQYEEVQRVLREEIVNPLRKNMFVRADRVMKLRTLLEKLSSVSG-LTSEEKDPEEFLTSLVAQILNAEPFLKLSSGQD----AYHYQLFVEKDDHLNLPTVQQLLEQSFLTSNIRLKEVPSCLIIQMPRFGKSFKMYQKIQPTLLLDVTDIIEDSPRQCTVCGKLAEFECKECYGQCGAGLESTAFCLQCLETVHQHERRTNHEPKKLVVPMEFAILQEHCPVPRLYLELSAVVCIETSHYVCFVKCGSGSEAPWCFFDSMADRKGEQNGYNIPEMVPCPDFPYWL 502

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BLAST of SMED30004380 vs. TrEMBL
Match: A0A0C9QF68 (CYLD protein OS=Fopius arisanus OX=64838 GN=CYLD PE=4 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 8.870e-15
Identity = 78/326 (23.93%), Postives = 155/326 (47.55%), Query Frame = 3

Query: 1788 KTRILENSSKLNFVESVIVALFAKS---DNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHH-------MLEDLAKCFGEINLFELDE--ISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFC----------QKHMCKHPEAVKLP-EFNLWNK----SKIFLNLSSIIYKTKLYYGALVK-QKGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFL 2666
            K R ++      ++++ + ++FA +   DNL F        PQYE +++VL  +I+ PLR+  +V  +       +LE L+   G  +  +  E  +++ ++   N E FL L S +     +   +LF++  ++L+  T +QLL  S + + I  +++PSCLIIQ  +  KS   Y  + P   ++++ +I +  ++C  C  +A F+C  C     + + S  FC          ++     P+ + +P EF +  +     +++L LS+++     +Y + VK   GSE  W  +     +  E++G     +    +  Y+L
Sbjct:  449 KYRGIQGHHNSCYLDATLFSMFAFTSVFDNLLFRPPSEKDCPQYEEVQRVLREEIVNPLRKNMFVQANRVMKLRTLLEKLSSISGLTSEEKDPEEFLTSLVAQILNAEPFLKLSSGQD----AYHYQLFVEKDDQLNLPTVQQLLEQSFLTSNIRLKEVPSCLIIQMPRFGKSFKMYPKIQPTLLLDVTDIIEDSPRQCTVCGKLAEFECKECYGQCGMGLESIAFCLPCLDQAHRHERRTNHDPKELSVPTEFQILQEHCPVPRLYLELSAVVCIETSHYVSFVKCGSGSEAPWCFFDSMADRKGEQNGYNIPEMVPCPDFPYWL 770

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BLAST of SMED30004380 vs. Ensembl Cavefish
Match: cylda (CYLD lysine 63 deubiquitinase [Source:NCBI gene;Acc:103044817])

HSP 1 Score: 73.9442 bits (180), Expect = 6.250e-13
Identity = 77/367 (20.98%), Postives = 165/367 (44.96%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFCQK-----HMCKHPEA-------VKLP---EFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y   +++L  +I+ PLR  GYV    +  L +      L +++  S F S   + E FL+++ +           R     +Q     ++F+D K+++   TS+QLL  S I + + F + PSCLIIQ  +  K    +  + P   ++I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC+K     H+  HP         + +P   +  +W +       + L +++     +Y A VK   +++ W      + +   ++G     +S   E+  +L++  +E+      +   + + ++ + +  +Y +  ++ Y
Sbjct:  599 YLDSTLFCLFSFSSVLDTVL--LRPKSKTDVEYYLETQELLRTEIVNPLRIHGYVCATKIMKLRRI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKLRSAGQKVQDCYFYQIFMDKKDKVLVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLEDTPRECRICGGLALYECRECYEDADITAGKIKQ----FCEKCNTQVHL--HPRRKTHRYGKLSVPKELQEGVWRQGSFPHQQMELFAVLCIETSHYVAFVKYGAADSAWLFFDSMADRDGGQNGFNIPQVSPCPEVGAYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 952

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Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFCQK-----HMCKHPEA-------VKLP---EFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y   +++L  +I+ PLR  GYV    +  L +      L +++  S F S   + E FL+++ +           R     +Q     ++F+D K+++   TS+QLL  S I + + F + PSCLIIQ  +  K    +  + P   ++I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC+K     H+  HP         + +P   +  +W +       + L +++     +Y A VK   +++ W      + +   ++G     +S   E+  +L++  +E+      +   + + ++ + +  +Y +  ++ Y
Sbjct:  599 YLDSTLFCLFSFSSVLDTVL--LRPKSKTDVEYYLETQELLRTEIVNPLRIHGYVCATKIMKLRRI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKLRSAGQKVQDCYFYQIFMDKKDKVLVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLEDTPRECRICGGLALYECRECYEDADITAGKIKQ----FCEKCNTQVHL--HPRRKTHRYGKLSVPKELQEGVWRQGSFPHQQMELFAVLCIETSHYVAFVKYGAADSAWLFFDSMADRDGGQNGFNIPQVSPCPEVGAYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 952

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BLAST of SMED30004380 vs. Ensembl Cavefish
Match: cylda (CYLD lysine 63 deubiquitinase [Source:NCBI gene;Acc:103044817])

HSP 1 Score: 73.9442 bits (180), Expect = 6.613e-13
Identity = 77/367 (20.98%), Postives = 165/367 (44.96%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFCQK-----HMCKHPEA-------VKLP---EFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y   +++L  +I+ PLR  GYV    +  L +      L +++  S F S   + E FL+++ +           R     +Q     ++F+D K+++   TS+QLL  S I + + F + PSCLIIQ  +  K    +  + P   ++I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC+K     H+  HP         + +P   +  +W +       + L +++     +Y A VK   +++ W      + +   ++G     +S   E+  +L++  +E+      +   + + ++ + +  +Y +  ++ Y
Sbjct:  560 YLDSTLFCLFSFSSVLDTVL--LRPKSKTDVEYYLETQELLRTEIVNPLRIHGYVCATKIMKLRRI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKLRSAGQKVQDCYFYQIFMDKKDKVLVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLEDTPRECRICGGLALYECRECYEDADITAGKIKQ----FCEKCNTQVHL--HPRRKTHRYGKLSVPKELQEGVWRQGSFPHQQMELFAVLCIETSHYVAFVKYGAADSAWLFFDSMADRDGGQNGFNIPQVSPCPEVGAYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 913

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BLAST of SMED30004380 vs. Ensembl Cavefish
Match: cylda (CYLD lysine 63 deubiquitinase [Source:NCBI gene;Acc:103044817])

HSP 1 Score: 73.559 bits (179), Expect = 6.849e-13
Identity = 77/367 (20.98%), Postives = 165/367 (44.96%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHIC-----ITIGALEISSGFFCQK-----HMCKHPEA-------VKLP---EFNLWNKSKIF---LNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            +++S +  LF+ S  LD ++  + P+ +     Y   +++L  +I+ PLR  GYV    +  L +      L +++  S F S   + E FL+++ +           R     +Q     ++F+D K+++   TS+QLL  S I + + F + PSCLIIQ  +  K    +  + P   ++I+ L+ +  ++C  C  +A ++C  C     IT G ++     FC+K     H+  HP         + +P   +  +W +       + L +++     +Y A VK   +++ W      + +   ++G     +S   E+  +L++  +E+      +   + + ++ + +  +Y +  ++ Y
Sbjct:  411 YLDSTLFCLFSFSSVLDTVL--LRPKSKTDVEYYLETQELLRTEIVNPLRIHGYVCATKIMKLRRI-----LEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKLRSAGQKVQDCYFYQIFMDKKDKVLVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLEDTPRECRICGGLALYECRECYEDADITAGKIKQ----FCEKCNTQVHL--HPRRKTHRYGKLSVPKELQEGVWRQGSFPHQQMELFAVLCIETSHYVAFVKYGAADSAWLFFDSMADRDGGQNGFNIPQVSPCPEVGAYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 764

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BLAST of SMED30004380 vs. Ensembl Cavefish
Match: cyldl (cylindromatosis (turban tumor syndrome), like [Source:ZFIN;Acc:ZDB-GENE-131127-190])

HSP 1 Score: 53.5286 bits (127), Expect = 1.077e-6
Identity = 59/234 (25.21%), Postives = 104/234 (44.44%), Query Frame = 3

Query: 1788 KTRILENSSKLNFVESVIVALFAKSDNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE--------------RKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMC 2447
            K R ++      +++S +  LF  S  LD L+ +   Q   + I++ L  +I+ PLR  G+V+   +  L +   E         S   +T    E FL+LI  +              +K   S   ++F+D    L   T +QLL  S   + +  E++PSCLI+   +  K    +  +IP   ++I+ L+ N  ++C+ C  +A  +C  C        ++GF   KH+C
Sbjct:  378 KQRGIQGHCNSCYMDSALF-LFTCSSVLDSLLYKGTNQ-NDKHIQETLRKEIVGPLRT-GFVADRSVMKLRQQLQERGH------SPSYTTDEKPEEFLTLIMQDILSLEPPLKKPLGMKKVETSFFYQIFVDYNNTLVLPTVQQLLEHSFYTSCLRLEEVPSCLILTMPRSGKQFKMFPKIIPSLELDITALLYNP-QQCVLCGQLAHVECTECFGDPVFG-NTGF---KHLC 597

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BLAST of SMED30004380 vs. Ensembl Nematostella
Match: EDO47295 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMM7])

HSP 1 Score: 49.2914 bits (116), Expect = 6.316e-6
Identity = 68/324 (20.99%), Postives = 137/324 (42.28%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLI---SQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCF---GEINLFELDE------ISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHC-DSVAFFQCHICITIGALEISSGFFCQKHMCK----HPE-------AVKLP-EFNLWNK-----SKIFLNLSSIIYKTKLYYGALVK-QKGSENIWSSY-----KVNEKDGMTFANLSYDKEISYFLQLNEDEM 2687
            +++S + ++FA +   D L+    Q +    Y+ ++KVL  +I+ PLR  G+V    +  L +     G  +    +E      ++T +      E  L L S+ R +  S   ++  +  E +   T + L+  S +   +   ++PSCLI+Q  +       Y  + P  +++I+ ++ N  + C+ C +  + F+C  C       I    FC +  CK    HP         + +P E++ + +      +  + L +++     +Y A VK  +G +  W  +     +  E +G     +    E S +L    DE+
Sbjct:  127 YLDSTLYSMFAFTTVFDTLLHRERQSSDLEDYDKVQKVLKEEIVNPLRRNGFVRADRVLRLRRLLDKLGSTSGLTDEEKDPEEFLNTLLHQVLKSESLLQLKSHGRCEE-SNYYQIITEKDEGIKLATVQTLIEQSFMAADLKLAEVPSCLILQMPRFGNKYKMYDIIFPNTTLDITDILDNVPRPCVLCGEQASTFECKECYEEKIFSIGITSFC-RDCCKKVHSHPRRTSHKLTPIIVPREYSQYARRDGPLERYTMELFAVVCIQTSHYVAFVKCGQGPDAPWCFFDSMADRKGESNGYNIPAVRACPEASRWLLAKPDEI 448

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BLAST of SMED30004380 vs. Ensembl Medaka
Match: cyldb (ubiquitin carboxyl-terminal hydrolase CYLD [Source:NCBI gene;Acc:101163809])

HSP 1 Score: 73.559 bits (179), Expect = 5.761e-13
Identity = 78/336 (23.21%), Postives = 147/336 (43.75%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDE--ISTFISTFSNG----EFFLSLISYERKKSMSIQLKLFIDLKERLDYI-TSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALE----------ISSGFFCQKHMCKH-PEAVKLPEFNLWNKSKIFLNLSSIIYKTKLYYGALVKQKGSENIW------SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIY 2759
            ++++ + +LF+ S  +D  I Q   +PQ + +   L   I+  LR  G+V    + +  K  G  + F  DE     FIS         E  L L S       +  L++F++ KE+L +I T +QLL+ S +   + FE +PSCLIIQ  +       + ++IP   ++I+ L+ N  ++C  C  +A F+C  C+    L+           ++        C H P AV +P        +  + L +++     +Y + VK     + W      +    +++ G     +    E+  FL  +E+E  +       E ++ ++ + + L+Y
Sbjct:  362 YLDATLFSLFSSSVVVD-RICQKPAEPQ-QPLNCTLR-TIVNRLRRQGFVPAECVMNFRKQLG-CDTFRTDEKDPEEFISVLFQKVLCIEPLLKLRSEGETSQGANTLQIFLE-KEQLQHIPTVQQLLDTSCMSEDLKFEMVPSCLIIQMPRFGNKYKMFSHIIPSMELDITDLLHNSPRECFICGHLAEFECPQCLPDRKLQPGRIKQYCLTCNTQVHSHPSRCSHFPRAVTVPADADTPVPRHTMQLFAVLCIQTSHYVSFVKYGPEPHSWVFFDSMADRCGDDQSGYNIPEIRACPELGDFLCQSEEEQARSNPLQAPELVRRLLCDSYMLLY 692

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BLAST of SMED30004380 vs. Ensembl Medaka
Match: cylda (CYLD lysine 63 deubiquitinase [Source:NCBI gene;Acc:101156964])

HSP 1 Score: 73.1738 bits (178), Expect = 9.424e-13
Identity = 60/227 (26.43%), Postives = 111/227 (48.90%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSG---FFCQK 2438
            +++S +  LF+ S  LD ++  + PQ +     Y   +++L  +I+ PLR  GYV    +  L +      L +++  S F S   + E FL ++ +           R     +Q     ++F+D K+++   T +QLL  S I + + F + PSCLIIQ  +  K    +  + P   ++I+ L+ +  ++C  C  +AF++C  C   G  +I++G    FC+K
Sbjct:  564 YLDSTLFCLFSFSSVLDTVL--LRPQSKTDVEYYRETQELLRTEIVNPLRIHGYVCATKVMKLRRI-----LEKVEAASGFTSEEKDPEEFLIILFHHILRVDPLLKLRSAGQKVQDCYFYQIFMDKKDKVGVPTIQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLEDTPRECRICGGLAFYECRDCYDDG--DITAGKIKQFCEK 781

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BLAST of SMED30004380 vs. Ensembl Medaka
Match: cylda (CYLD lysine 63 deubiquitinase [Source:NCBI gene;Acc:101156964])

HSP 1 Score: 73.1738 bits (178), Expect = 9.933e-13
Identity = 60/227 (26.43%), Postives = 111/227 (48.90%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQ-----YEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYE----------RKKSMSIQ----LKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSG---FFCQK 2438
            +++S +  LF+ S  LD ++  + PQ +     Y   +++L  +I+ PLR  GYV    +  L +      L +++  S F S   + E FL ++ +           R     +Q     ++F+D K+++   T +QLL  S I + + F + PSCLIIQ  +  K    +  + P   ++I+ L+ +  ++C  C  +AF++C  C   G  +I++G    FC+K
Sbjct:  603 YLDSTLFCLFSFSSVLDTVL--LRPQSKTDVEYYRETQELLRTEIVNPLRIHGYVCATKVMKLRRI-----LEKVEAASGFTSEEKDPEEFLIILFHHILRVDPLLKLRSAGQKVQDCYFYQIFMDKKDKVGVPTIQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLEDTPRECRICGGLAFYECRDCYDDG--DITAGKIKQFCEK 820

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BLAST of SMED30004380 vs. Ensembl Medaka
Match: cyldl (ubiquitin carboxyl-terminal hydrolase CYLD [Source:NCBI gene;Acc:101168449])

HSP 1 Score: 62.003 bits (149), Expect = 2.764e-9
Identity = 68/327 (20.80%), Postives = 139/327 (42.51%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFS----NGEFFLSLI-------------SYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGF--FCQ----------KHMCKHPEAVKLPEFNLWNK-----SKIFLNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEM 2687
            ++++ + +LF+ S  +D ++ +     Q   I+K L   I+ PLR  G+V         +C   + L +L +   +  +F+    + E FL ++             S   K   S   ++F+D    L   T +QLL  S     +   ++PSCLI+Q  +  K    +  +IP   ++I+ L+    ++C+ C ++A  +C  C       + +GF  FC+          K     P A+++P+  +        ++  L L +++     +Y + VK     + W      + +  E DG     +    E++ +L+++  E+
Sbjct:  421 YMDAALFSLFSCSSAMDSMLFKTTTS-QDAPIQKTLLRDIVVPLRSKGFV---------ECQHVMKLRQLLQKHGYSRSFTTEEKDPEEFLIVVMHHILALDPLLKLSAAGKVQESYCYQIFLDQNHCLVLPTVQQLLEHSFHSAGLRLAEVPSCLILQMPRFGKKFKMFDKIIPSLELDITDLLSEGPQQCIMCGNLAVEECADCFKDPTFSL-TGFKIFCKKCSAQVHSHPKRRSHQPTALEIPKGYMGRGIPHTLTRDRLELFAVLCIETSHYVSFVKHGPKSHDWIFFDSMADRQGETDGFNIPEVHACPEVAIYLEMSPAEL 736

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BLAST of SMED30004380 vs. Ensembl Medaka
Match: cyldl (ubiquitin carboxyl-terminal hydrolase CYLD [Source:NCBI gene;Acc:101168449])

HSP 1 Score: 61.6178 bits (148), Expect = 2.967e-9
Identity = 68/327 (20.80%), Postives = 139/327 (42.51%), Query Frame = 3

Query: 1824 FVESVIVALFAKSDNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFS----NGEFFLSLI-------------SYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGF--FCQ----------KHMCKHPEAVKLPEFNLWNK-----SKIFLNLSSIIYKTKLYYGALVKQKGSENIW-----SSYKVNEKDGMTFANLSYDKEISYFLQLNEDEM 2687
            ++++ + +LF+ S  +D ++ +     Q   I+K L   I+ PLR  G+V         +C   + L +L +   +  +F+    + E FL ++             S   K   S   ++F+D    L   T +QLL  S     +   ++PSCLI+Q  +  K    +  +IP   ++I+ L+    ++C+ C ++A  +C  C       + +GF  FC+          K     P A+++P+  +        ++  L L +++     +Y + VK     + W      + +  E DG     +    E++ +L+++  E+
Sbjct:  421 YMDAALFSLFSCSSAMDSMLFKTTTS-QDAPIQKTLLRDIVVPLRSKGFV---------ECQHVMKLRQLLQKHGYSRSFTTEEKDPEEFLIVVMHHILALDPLLKLSAAGKVQESYCYQIFLDQNHCLVLPTVQQLLEHSFHSAGLRLAEVPSCLILQMPRFGKKFKMFDKIIPSLELDITDLLSEGPQQCIMCGNLAVEECADCFKDPTFSL-TGFKIFCKKCSAQVHSHPKRRSHQPTALEIPKGYMGRGIPHTLTRDRLELFAVLCIETSHYVSFVKHGPKSHDWIFFDSMADRQGETDGFNIPEVHACPEVAIYLEMSPAEL 736

[Close]

BLAST of SMED30004380 vs. Planmine SMEST
Match: SMESG000007103.1 (SMESG000007103.1)

HSP 1 Score: 1732.23 bits (4485), Expect = 0.000e+0
Identity = 861/879 (97.95%), Postives = 870/879 (98.98%), Query Frame = 3

Query:  147 MFVVQNKEYEIEENKKQMIIDLMIIIMEHEGDIIKTNAMNNSALSLAYKIKDKKYYNLLLNCFKSIELLSDEFGRNFLRQIVIDKADVLSNTLDKCLIKDCHTEFLLDLGLMALKQKSNDIYKNILDHCKTKDIILKNGETFLTNLVKNKEDISIITDIVTSKYFDINKVNLRNESILMIACEQLNENIVKFLVRSGCDVTYNSYGAVQATINAKLKNPDLQNIDQISNNIMNFLWKPQVTDSQQRSLKSSQIERVVRIPNDIGKFNNQYYQDYYGQPQAYHPHKEQFVLDLLKMLIDSKGNLILENAQKVNFLSKSYDYQDKSYFSQLLKRCPGNLQILSNESGIKLLFKLSSEAKLNALEFILSKIEIAGNSNENLLKLAVRVLKNGGIETYNKIIKMCIDPNAIFDDGETFISSLFKNNVKESIIKFVIESGLFDAKKTNNKAENALMLACSRLMTTVIPILLNQGCEIAYSGYNAVIMTIVGNQTLKSEESKLKMNEILSLFFDHASKKNPVEVIGKNKIGNSKKSQISTYLQLAISKYQLKIKTRILENSSKLNFVESVIVALFAKSDNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCKHPEAVKLPEFNLWNKSKIFLNLSSIIYKTKLYYGALVKQKGSENIWSSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            MFVVQNKEYEIEENKKQMIIDLMIIIMEHEGDIIKTNAMNNSALSLAYKIKDKKYYNLLLNCFKSIELLSDEFGRNFLRQIVIDKADVLSNTLDKCLIKDCHTEFLLDLGLMALKQKSNDIYKNILDHCKTKDIILKNGETFLTNLVKNKEDISIITDIVTSKYFDINKVNLRNESILMIACEQLNENIVKFLVRSGCDVTYNSYGAVQATINAKLKNPDLQNIDQISNNIMNFLWKPQVTDSQQRSLKSSQIERVVRIPNDIGKFN QYYQDYYGQPQAYHPHKEQFVLDLLKMLIDSKGNLILENAQKVNFLSKSYDYQDKSYFSQLL+RCPGNLQILSNESGIKLLFKLSSE KL ALEFILSKIE+AGNSNENLLKLAV+VLKNGGIETYNKIIKMCI+ +AIFDDGETFISSLFKNNVKESIIK VIESGLFDAKKTNNKAENALMLACSRLMTTVIPILLNQGCEIAYSGYNAVIMTIVGNQTLKSEESKLKMNEILSLFFDHASKK PVEVIG+NKI NSKKSQISTYLQLAISKYQLKIKTRILENSSKLNFVESVIVALFAKSDNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKE LDYITSEQLLNIS+IQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLII+KFKKCLHCDSVAFFQCHICITIGALEISSGFFC+KHMCKHPEAVKLPEFNLWNKSKIFLNLSSIIYKTKLYYGALVKQKGSENIWSSYKVNEKDGM FANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY
Sbjct:    1 MFVVQNKEYEIEENKKQMIIDLMIIIMEHEGDIIKTNAMNNSALSLAYKIKDKKYYNLLLNCFKSIELLSDEFGRNFLRQIVIDKADVLSNTLDKCLIKDCHTEFLLDLGLMALKQKSNDIYKNILDHCKTKDIILKNGETFLTNLVKNKEDISIITDIVTSKYFDINKVNLRNESILMIACEQLNENIVKFLVRSGCDVTYNSYGAVQATINAKLKNPDLQNIDQISNNIMNFLWKPQVTDSQQRSLKSSQIERVVRIPNDIGKFNYQYYQDYYGQPQAYHPHKEQFVLDLLKMLIDSKGNLILENAQKVNFLSKSYDYQDKSYFSQLLERCPGNLQILSNESGIKLLFKLSSETKLKALEFILSKIEMAGNSNENLLKLAVQVLKNGGIETYNKIIKMCIEFDAIFDDGETFISSLFKNNVKESIIKSVIESGLFDAKKTNNKAENALMLACSRLMTTVIPILLNQGCEIAYSGYNAVIMTIVGNQTLKSEESKLKMNEILSLFFDHASKKKPVEVIGQNKIDNSKKSQISTYLQLAISKYQLKIKTRILENSSKLNFVESVIVALFAKSDNLDFLISQVNPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKEGLDYITSEQLLNISIIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIIDKFKKCLHCDSVAFFQCHICITIGALEISSGFFCRKHMCKHPEAVKLPEFNLWNKSKIFLNLSSIIYKTKLYYGALVKQKGSENIWSSYKVNEKDGMIFANLSYDKEISYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 879

[Close]

BLAST of SMED30004380 vs. Planmine SMEST
Match: SMESG000007140.1 (SMESG000007140.1)

HSP 1 Score: 187.963 bits (476), Expect = 5.146e-51
Identity = 119/389 (30.59%), Postives = 206/389 (52.96%), Query Frame = 3

Query: 1722 NSKKSQISTYLQLAISKYQLKIKTRILENSSKLNFVESVIVALFAKSDNLDFLISQV----NPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKC-------FGEINLFELD--EISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCKHPEAVKLPEFNLWNKSKIFLNLSSIIYKTKLYYGALVKQ--KGSENIWSSYKVNEKD------------------GMTFANLSYDKEI--SYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            N KKS+ S  +   ++   +    + ++ ++   + +S + ALF KSD LD+LIS +       P  +  R+++AWKI+YPLR+ G+VS H  +++          F E+   E D   +ST +S     E  LS+I +   ++ S+ ++LF+ +  ++ ++TSE++L ISM+QN I+F ++P+CLI+QA +D+K   SY   +PL  IEIS++  N  K C  C+  A FQC  C+    L+I+  F C +H C+HP   KL    + +KSK+F+ L +II   K ++ + VKQ  + +       +  + D                    ++A     K I  S FL  ++++MK+ I  +D   ++ ++K+ +  IY N +  CY
Sbjct:  111 NVKKSETSDQIVCGLNSIVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEHEADPITKEFREIIAWKIVYPLRKNGFVSFHYTQEMRNAIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCQTNSMFMQLFLTVDNKVSFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYEYALPLNEIEISQICSNYLKNCSKCNGEAEFQCKKCLR-NELDITCTFRCSQHKCQHPACTKLRPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDSMSSQSISNSYAIPRVSKAIKESEFLNSSKEKMKESIELYDSGDIKRIIKDSYIFIYHNKSKTCY 498

[Close]

BLAST of SMED30004380 vs. Planmine SMEST
Match: SMESG000007140.1 (SMESG000007140.1)

HSP 1 Score: 183.726 bits (465), Expect = 5.504e-50
Identity = 102/295 (34.58%), Postives = 170/295 (57.63%), Query Frame = 3

Query: 1722 NSKKSQISTYLQLAISKYQLKIKTRILENSSKLNFVESVIVALFAKSDNLDFLISQV----NPQPQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKC-------FGEINLFELD--EISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCKHPEAVKLPEFNLWNKSKIFLNLSSIIYKTKLYYGALVKQ 2567
            N KKS+ S  +   ++   +    + ++ ++   + +S + ALF KSD LD+LIS +       P  +  R+++AWKI+YPLR+ G+VS H  +++          F E+   E D   +ST +S     E  LS+I +   ++ S+ ++LF+ +  ++ ++TSE++L ISM+QN I+F ++P+CLI+QA +D+K   SY   +PL  IEIS++  N  K C  C+  A FQC  C+    L+I+  F C +H C+HP   KL    + +KSK+F+ L +II   K ++ + VKQ
Sbjct:  111 NVKKSETSDQIVCGLNSIVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEHEADPITKEFREIIAWKIVYPLRKNGFVSFHYTQEMRNAIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCQTNSMFMQLFLTVDNKVSFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYEYALPLNEIEISQICSNYLKNCSKCNGEAEFQCKKCLR-NELDITCTFRCSQHKCQHPACTKLRPDTVKSKSKVFMELQAIICIEKCHFVSFVKQ 404

[Close]

BLAST of SMED30004380 vs. Planmine SMEST
Match: SMESG000056847.1 (SMESG000056847.1)

HSP 1 Score: 188.348 bits (477), Expect = 1.024e-48
Identity = 121/389 (31.11%), Postives = 210/389 (53.98%), Query Frame = 3

Query: 1722 NSKKSQISTYLQLAISKYQLKIKTRILENSSKLNFVESVIVALFAKSDNLDFLISQV-NPQ---PQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKC-------FGEINLFELD--EISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCKHPEAVKLPEFNLWNKSKIFLNLSSIIYKTKLYYGALVKQ--KGSENIWSSYKVNEKD------------------GMTFANLSYDKEI--SYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            N KKS+ S  +   ++   +    + ++ ++   + +S + ALF KSD LD+LIS + N Q   P  +  R+++AW+I+YPLR+ G+VS H  +++          F E+   E D   +ST +S     E  LS+I +   K+ S+ ++LF+ + +++ ++TSE++L ISM+QN I+F ++P+CLI+QA +D+K   SY+  +PL  IEIS++  N  K C  C+  A FQC  C+    L+I+  F C +H C+HP   KL    + +KSK+F+ L +II   K ++ + VKQ  + +       +  + D                    ++A     K I  S FL  ++++MK+ I  +D   ++ ++K+ +  IY N +  CY
Sbjct:  685 NVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLG-DELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDSMSSQSISNSYAIPRVSKAIKESEFLNSSKEKMKESIELYDSGDIKRIIKDSYIFIYHNKSKTCY 1072

[Close]

BLAST of SMED30004380 vs. Planmine SMEST
Match: SMESG000056847.1 (SMESG000056847.1)

HSP 1 Score: 188.734 bits (478), Expect = 1.061e-48
Identity = 122/389 (31.36%), Postives = 208/389 (53.47%), Query Frame = 3

Query: 1722 NSKKSQISTYLQLAISKYQLKIKTRILENSSKLNFVESVIVALFAKSDNLDFLISQV-NPQ---PQYEAIRKVLAWKIIYPLREFGYVSHHMLEDLAKC-------FGEINLFELD--EISTFISTFSNGEFFLSLISYERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLIIQAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICITIGALEISSGFFCQKHMCKHPEAVKLPEFNLWNKSKIFLNLSSIIYKTKLYYGALVKQKGSENIWSSYKVNEKD--------------------GMTFANLSYDKEI--SYFLQLNEDEMKQHISYHDMEFLQLVMKNIHFLIYDNNALNCY 2783
            N KKS+ S  +   ++   +    + ++ ++   + +S + ALF KSD LD+LIS + N Q   P  +  R+++AW+I+YPLR+ G+VS H  +++          F E+   E D   +ST +S     E  LS+I +   K+ S+ ++LF+ + +++ ++TSE++L ISM+QN I+F ++P+CLI+QA +D+K   SY+  +PL  IEIS++  N  K C  C+  A FQC  C+    L+I+  F C +H C+HP   KL    + +KSK+F+ L +II   K ++ + VKQ          K+  K                       ++A     K I  S FL  ++++MK+ I  +D   ++ ++K+ +  IY N +  CY
Sbjct:  783 NVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLG-DELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDSMSSQSISNSYAIPRVSKAIKESEFLNSSKEKMKESIELYDSGDIKRIIKDSYIFIYHNKSKTCY 1170

The following BLAST results are available for this feature:

BLAST of SMED30004380 vs. Ensembl Human
BLAST of SMED30004380 vs. Ensembl Celegans
BLAST of SMED30004380 vs. Ensembl Fly
BLAST of SMED30004380 vs. Ensembl Zebrafish
BLAST of SMED30004380 vs. Ensembl Xenopus
BLAST of SMED30004380 vs. Ensembl Mouse
BLAST of SMED30004380 vs. UniProt/SwissProt
BLAST of SMED30004380 vs. TrEMBL
BLAST of SMED30004380 vs. Ensembl Cavefish
BLAST of SMED30004380 vs. Ensembl Sea Lamprey
BLAST of SMED30004380 vs. Ensembl Yeast
BLAST of SMED30004380 vs. Ensembl Nematostella
BLAST of SMED30004380 vs. Ensembl Medaka
BLAST of SMED30004380 vs. Planmine SMEST

BLAST of SMED30004380 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CYLD	5.329e-12	21.15	CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;...	[more]
CYLD	6.833e-12	21.15	CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;...	[more]
CYLD	6.833e-12	21.15	CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;...	[more]
CYLD	7.182e-12	21.15	CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;...	[more]
CYLD	7.182e-12	21.15	CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;...	[more]

BLAST of SMED30004380 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
cyld-1	3.760e-11	24.46	CYLinDromatosis (Human disease gene) homolog [Sou...	[more]
cyld-1	4.003e-11	24.46	CYLinDromatosis (Human disease gene) homolog [Sou...	[more]
cyld-1	4.166e-11	24.46	CYLinDromatosis (Human disease gene) homolog [Sou...	[more]

BLAST of SMED30004380 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
CYLD	1.021e-11	25.35	gene:FBgn0032210 transcript:FBtr0080070	[more]
CYLD	1.021e-11	25.35	gene:FBgn0032210 transcript:FBtr0080071	[more]
CYLD	1.576e-11	22.67	gene:FBgn0032210 transcript:FBtr0080072	[more]

BLAST of SMED30004380 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cyldl	8.618e-14	24.30	cylindromatosis (turban tumor syndrome), like [Sou...	[more]
cyldl	8.618e-14	24.30	cylindromatosis (turban tumor syndrome), like [Sou...	[more]
cylda	3.024e-13	21.80	cylindromatosis (turban tumor syndrome), a [Source...	[more]
cylda	3.195e-13	21.80	cylindromatosis (turban tumor syndrome), a [Source...	[more]
cylda	3.195e-13	21.80	cylindromatosis (turban tumor syndrome), a [Source...	[more]

BLAST of SMED30004380 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tril	1.656e-11	21.20	TLR4 interactor with leucine-rich repeats [Source:...	[more]
tril	1.891e-11	21.20	TLR4 interactor with leucine-rich repeats [Source:...	[more]
tril	1.991e-11	21.20	TLR4 interactor with leucine-rich repeats [Source:...	[more]
tril	2.292e-11	21.20	TLR4 interactor with leucine-rich repeats [Source:...	[more]
tril	2.196e-7	20.62	TLR4 interactor with leucine-rich repeats [Source:...	[more]

BLAST of SMED30004380 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Cyld	2.009e-12	21.15	CYLD lysine 63 deubiquitinase [Source:MGI Symbol;A...	[more]
Cyld	2.454e-12	21.31	CYLD lysine 63 deubiquitinase [Source:MGI Symbol;A...	[more]
Cyld	2.454e-12	21.31	CYLD lysine 63 deubiquitinase [Source:MGI Symbol;A...	[more]
Cyld	2.557e-12	21.31	CYLD lysine 63 deubiquitinase [Source:MGI Symbol;A...	[more]
Cyld	2.557e-12	21.31	CYLD lysine 63 deubiquitinase [Source:MGI Symbol;A...	[more]

BLAST of SMED30004380 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q1RMU2\|CYLD_BOVIN	5.760e-12	21.70	Ubiquitin carboxyl-terminal hydrolase CYLD OS=Bos ...	[more]
sp\|Q66H62\|CYLD_RAT	1.240e-11	21.43	Ubiquitin carboxyl-terminal hydrolase CYLD OS=Ratt...	[more]
sp\|Q80TQ2\|CYLD_MOUSE	1.789e-11	21.31	Ubiquitin carboxyl-terminal hydrolase CYLD OS=Mus ...	[more]
sp\|Q5RED8\|CYLD_PONAB	3.172e-11	21.43	Ubiquitin carboxyl-terminal hydrolase CYLD OS=Pong...	[more]
sp\|Q9NQC7\|CYLD_HUMAN	3.282e-11	21.15	Ubiquitin carboxyl-terminal hydrolase CYLD OS=Homo...	[more]

BLAST of SMED30004380 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
F4WWF9	5.700e-15	23.18	Putative ubiquitin carboxyl-terminal hydrolase CYL...	[more]
A0A158NKM7	6.476e-15	23.18	USP domain-containing protein OS=Atta cephalotes O...	[more]
A0A195DG65	6.999e-15	23.18	Ubiquitin carboxyl-terminal hydrolase CYLD OS=Trac...	[more]
A0A0L7R5H6	8.572e-15	23.64	Ubiquitin carboxyl-terminal hydrolase CYLD OS=Habr...	[more]
A0A0C9QF68	8.870e-15	23.93	CYLD protein OS=Fopius arisanus OX=64838 GN=CYLD P...	[more]

BLAST of SMED30004380 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cylda	6.250e-13	20.98	CYLD lysine 63 deubiquitinase [Source:NCBI gene;Ac...	[more]
cylda	6.250e-13	20.98	CYLD lysine 63 deubiquitinase [Source:NCBI gene;Ac...	[more]
cylda	6.613e-13	20.98	CYLD lysine 63 deubiquitinase [Source:NCBI gene;Ac...	[more]
cylda	6.849e-13	20.98	CYLD lysine 63 deubiquitinase [Source:NCBI gene;Ac...	[more]
cyldl	1.077e-6	25.21	cylindromatosis (turban tumor syndrome), like [Sou...	[more]

BLAST of SMED30004380 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of SMED30004380 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of SMED30004380 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO47295	6.316e-6	20.99	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SMED30004380 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cyldb	5.761e-13	23.21	ubiquitin carboxyl-terminal hydrolase CYLD [Source...	[more]
cylda	9.424e-13	26.43	CYLD lysine 63 deubiquitinase [Source:NCBI gene;Ac...	[more]
cylda	9.933e-13	26.43	CYLD lysine 63 deubiquitinase [Source:NCBI gene;Ac...	[more]
cyldl	2.764e-9	20.80	ubiquitin carboxyl-terminal hydrolase CYLD [Source...	[more]
cyldl	2.967e-9	20.80	ubiquitin carboxyl-terminal hydrolase CYLD [Source...	[more]

BLAST of SMED30004380 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000007103.1	0.000e+0	97.95	SMESG000007103.1	[more]
SMESG000007140.1	5.146e-51	30.59	SMESG000007140.1	[more]
SMESG000007140.1	5.504e-50	34.58	SMESG000007140.1	[more]
SMESG000056847.1	1.024e-48	31.11	SMESG000056847.1	[more]
SMESG000056847.1	1.061e-48	31.36	SMESG000056847.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30004380 ID=SMED30004380|Name=SMED30004380|organism=Schmidtea mediterranea sexual|type=transcript|length=2850bp
TTTTTTTTAAAAATATGTTCAAGGTCATATTTACTTTTTCTTAGAATTTG
ATAATTTATTGTTAATTCGATTATTCATATATACCAATATTGCAGGCTTC
TATTGAGAATTAACAGTTGGAGGAAGACAATTTACGGATAAAAAAAATGT
TTGTTGTTCAAAATAAAGAATATGAAATCGAGGAAAACAAAAAACAAATG
ATCATTGACTTGATGATAATAATTATGGAGCATGAAGGAGACATTATTAA
AACGAATGCCATGAACAATTCAGCTCTTTCATTGGCTTACAAAATAAAAG
ACAAAAAATATTATAACTTGTTGTTAAACTGTTTCAAATCTATTGAATTA
TTGTCCGATGAATTTGGAAGAAATTTCCTGAGACAAATAGTTATAGATAA
AGCTGATGTTCTTTCTAATACTCTTGACAAATGCTTAATCAAGGATTGTC
ACACAGAGTTTCTGTTGGATCTAGGATTAATGGCATTAAAACAAAAGTCC
AACGACATTTACAAAAATATACTTGACCATTGCAAAACCAAAGACATAAT
TTTGAAAAACGGAGAAACATTTCTGACAAATTTAGTAAAGAACAAAGAAG
ACATTTCAATTATTACGGATATTGTGACATCAAAATATTTTGATATAAAT
AAGGTAAATCTACGAAATGAATCCATTTTAATGATTGCTTGTGAGCAATT
AAATGAAAATATTGTGAAGTTTCTTGTGCGATCCGGCTGCGATGTGACAT
ACAATAGCTATGGAGCTGTACAAGCCACGATTAATGCCAAATTGAAAAAT
CCGGATCTTCAAAATATTGATCAGATTTCAAATAACATAATGAATTTTCT
ATGGAAACCACAAGTTACTGATTCGCAACAAAGATCTTTAAAAAGTTCTC
AAATTGAACGAGTTGTAAGAATTCCAAATGACATCGGGAAATTCAACAAC
CAATATTATCAAGATTATTACGGGCAACCTCAAGCTTATCATCCGCATAA
AGAACAGTTCGTATTGGATCTGTTGAAAATGTTAATAGACAGCAAAGGGA
ATTTAATATTGGAAAATGCTCAAAAAGTCAATTTTTTATCAAAATCATAT
GATTATCAAGACAAAAGCTACTTCAGTCAACTGTTGAAAAGATGTCCTGG
AAATTTACAAATCCTTTCTAATGAATCCGGAATTAAATTATTATTTAAAC
TGTCAAGTGAAGCTAAGTTGAACGCTTTGGAATTTATTTTATCAAAAATC
GAAATTGCGGGAAATTCAAATGAGAATCTACTAAAATTGGCAGTTCGAGT
ATTAAAAAATGGCGGTATAGAAACATATAATAAAATAATTAAAATGTGCA
TTGATCCCAATGCAATTTTTGATGATGGTGAAACTTTTATAAGCAGTCTT
TTCAAGAATAATGTAAAAGAATCAATTATTAAATTTGTTATTGAATCGGG
TCTTTTCGATGCTAAAAAGACTAATAATAAAGCGGAAAACGCATTAATGT
TGGCCTGTAGCCGATTGATGACCACTGTGATTCCGATTTTATTGAACCAG
GGATGTGAAATAGCTTATTCTGGTTACAATGCTGTGATTATGACGATTGT
AGGAAATCAAACTTTGAAATCAGAGGAAAGTAAACTAAAAATGAATGAAA
TATTATCCTTATTTTTTGATCATGCGTCTAAAAAGAATCCTGTAGAAGTC
ATTGGAAAAAATAAAATTGGCAATAGTAAAAAGAGCCAGATTAGCACATA
TCTCCAGTTAGCTATTAGTAAATATCAGTTGAAAATAAAAACTCGAATTC
TGGAAAATTCATCAAAATTGAATTTCGTCGAGTCTGTTATTGTTGCTTTG
TTCGCTAAGTCAGACAATCTTGACTTTTTAATAAGCCAGGTAAATCCGCA
ACCACAATATGAAGCTATCAGAAAAGTTTTGGCTTGGAAAATCATTTATC
CTTTGCGCGAATTTGGATATGTTAGCCATCATATGTTAGAGGATTTAGCT
AAATGTTTTGGAGAAATTAATCTGTTCGAATTGGATGAAATATCAACTTT
CATATCGACTTTTTCAAATGGTGAATTTTTTCTCAGTTTGATTTCATATG
AACGGAAAAAATCCATGAGCATTCAATTAAAATTATTCATTGACCTTAAA
GAAAGACTCGATTACATAACGTCGGAGCAGCTATTAAACATTTCAATGAT
TCAAAACAAAATCTTGTTTGAAAAAATTCCTAGTTGTTTAATCATCCAGG
CAGCGAAAGATTCAAAAAGTGCCTTCAGTTATAGAAATCTCATTCCTTTG
AAATCTATTGAAATTTCAAAGCTTATTATCAACAAATTTAAGAAATGTCT
TCATTGCGATTCTGTGGCCTTTTTTCAATGTCATATCTGTATAACCATCG
GTGCTTTGGAGATTTCTTCTGGATTCTTTTGCCAAAAGCATATGTGTAAA
CATCCAGAAGCCGTGAAACTTCCTGAATTTAATTTATGGAACAAATCGAA
AATATTTTTAAATTTGTCATCAATAATCTACAAAACAAAGCTATATTATG
GTGCTCTCGTGAAACAAAAGGGCAGTGAGAATATTTGGTCATCATATAAA
GTGAATGAAAAGGATGGCATGACTTTCGCAAACTTATCGTACGATAAAGA
GATTTCATATTTTCTTCAATTAAACGAAGATGAAATGAAACAACACATAT
CGTATCATGATATGGAGTTCCTCCAATTAGTCATGAAAAATATTCATTTT
CTAATTTACGACAATAACGCTCTCAATTGTTATTGAGGAATCTTCAATTT
AAATTTTTTGATATTTTCATGTCATAATGGTCACATTTATACTTATTGTG

protein sequence of SMED30004380-orf-1

>SMED30004380-orf-1 ID=SMED30004380-orf-1|Name=SMED30004380-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=880bp
MFVVQNKEYEIEENKKQMIIDLMIIIMEHEGDIIKTNAMNNSALSLAYKI
KDKKYYNLLLNCFKSIELLSDEFGRNFLRQIVIDKADVLSNTLDKCLIKD
CHTEFLLDLGLMALKQKSNDIYKNILDHCKTKDIILKNGETFLTNLVKNK
EDISIITDIVTSKYFDINKVNLRNESILMIACEQLNENIVKFLVRSGCDV
TYNSYGAVQATINAKLKNPDLQNIDQISNNIMNFLWKPQVTDSQQRSLKS
SQIERVVRIPNDIGKFNNQYYQDYYGQPQAYHPHKEQFVLDLLKMLIDSK
GNLILENAQKVNFLSKSYDYQDKSYFSQLLKRCPGNLQILSNESGIKLLF
KLSSEAKLNALEFILSKIEIAGNSNENLLKLAVRVLKNGGIETYNKIIKM
CIDPNAIFDDGETFISSLFKNNVKESIIKFVIESGLFDAKKTNNKAENAL
MLACSRLMTTVIPILLNQGCEIAYSGYNAVIMTIVGNQTLKSEESKLKMN
EILSLFFDHASKKNPVEVIGKNKIGNSKKSQISTYLQLAISKYQLKIKTR
ILENSSKLNFVESVIVALFAKSDNLDFLISQVNPQPQYEAIRKVLAWKII
YPLREFGYVSHHMLEDLAKCFGEINLFELDEISTFISTFSNGEFFLSLIS
YERKKSMSIQLKLFIDLKERLDYITSEQLLNISMIQNKILFEKIPSCLII
QAAKDSKSAFSYRNLIPLKSIEISKLIINKFKKCLHCDSVAFFQCHICIT
IGALEISSGFFCQKHMCKHPEAVKLPEFNLWNKSKIFLNLSSIIYKTKLY
YGALVKQKGSENIWSSYKVNEKDGMTFANLSYDKEISYFLQLNEDEMKQH
ISYHDMEFLQLVMKNIHFLIYDNNALNCY*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron

Vocabulary: **INTERPRO**
Term	Definition
IPR002110	Ankyrin_rpt
IPR020683	Ankyrin_rpt-contain_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0016787	hydrolase activity
GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

Vocabulary: **biological process**
Term	Definition
GO:0016579	protein deubiquitination

Main menu

SMED30004380

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Owlery

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