cAMP-dependent protein kinase catalytic subunit alpha
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30004363 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 457.218 bits (1175), Expect = 8.186e-160 Identity = 225/352 (63.92%), Postives = 285/352 (80.97%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK E V E+ +++ FL++W++P+++ DQF R+KTLGTG+FG V LVK K+TG +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L + FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 457.218 bits (1175), Expect = 8.186e-160 Identity = 225/352 (63.92%), Postives = 285/352 (80.97%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK E V E+ +++ FL++W++P+++ DQF R+KTLGTG+FG V LVK K+TG +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L + FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]) HSP 1 Score: 449.899 bits (1156), Expect = 6.885e-157 Identity = 221/352 (62.78%), Postives = 280/352 (79.55%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK E V E+ +++ FL++W+NP+++ + F R KTLGTG+FG V LVK K T + +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGV+DIK HKWF DWI ++ ++V P +PK + DTSNFD YEEE +S EK EF +F
Sbjct: 1 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWF-ATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 446.432 bits (1147), Expect = 1.044e-155 Identity = 220/343 (64.14%), Postives = 279/343 (81.34%), Query Frame = 2
Query: 140 TDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
++ +V E+ +++ FL++W++P+++ DQF R+KTLGTG+FG V LVK K+TG +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L + FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 2 ASNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 446.432 bits (1147), Expect = 1.044e-155 Identity = 220/343 (64.14%), Postives = 279/343 (81.34%), Query Frame = 2
Query: 140 TDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
++ +V E+ +++ FL++W++P+++ DQF R+KTLGTG+FG V LVK K+TG +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L + FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 2 ASNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 452.595 bits (1163), Expect = 5.379e-158 Identity = 222/347 (63.98%), Postives = 279/347 (80.40%), Query Frame = 2
Query: 128 SSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
S+ + +AE + E+ +R+ F +RW+NP+++ D F R+KTLGTG+FG V LVK K +G +AMK+LDK+KVVKLKQVEHT+NEK+IL A+DFPFL+ + + FKDNS LY+V+++I GGEMF+H+R+ GRFSE +RFY AQ+VLAFEYLH+LD+IYRDLKPEN+LI + GY++ITDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK+KF +FS ELKD+L+ LLQ DLT+RYGNL+NGV DIKNHKWF G DWI ++ +++ P LPK + D SNFD YEEE IS EK EF +F
Sbjct: 36 SNGRLAAAETIKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF-GSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 381
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 451.44 bits (1160), Expect = 8.620e-158 Identity = 222/347 (63.98%), Postives = 278/347 (80.12%), Query Frame = 2
Query: 128 SSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
SSK ++ + E+ +R+ F +RW+NP+++ D F R+KTLGTG+FG V LVK K +G +AMK+LDK+KVVKLKQVEHT+NEK+IL A+DFPFL+ + + FKDNS LY+V+++I GGEMF+H+R+ GRFSE +RFY AQ+VLAFEYLH+LD+IYRDLKPEN+LI + GY++ITDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK+KF +FS ELKD+L+ LLQ DLT+RYGNL+NGV DIKNHKWF G DWI ++ +++ P LPK + D SNFD YEEE IS EK EF +F
Sbjct: 14 SSKDNKNSASLKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF-GSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 359
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 450.284 bits (1157), Expect = 3.315e-157 Identity = 224/351 (63.82%), Postives = 278/351 (79.20%), Query Frame = 2
Query: 122 SHSSKKTDSA--EEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
+H SK E V E+ +R+ F +RW+NP+++ D F R+KTLGTG+FG V LVK K +G +AMK+LDK+KVVKLKQVEHT+NEK+IL A+DFPFL+ + + FKDNS LY+V+++I GGEMF+H+R+ GRFSE +RFY AQ+VLAFEYLH+LD+IYRDLKPEN+LI + GY++ITDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK+KF +FS ELKD+L+ LLQ DLT+RYGNL+NGV DIKNHKWF G DWI ++ +++ P LPK + D SNFD YEEE IS EK EF +F
Sbjct: 21 NHKSKYISGGYLETVKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF-GSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 370
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 449.129 bits (1154), Expect = 4.367e-157 Identity = 223/349 (63.90%), Postives = 277/349 (79.37%), Query Frame = 2
Query: 122 SHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
S SS K + E+ +R+ F +RW+NP+++ D F R+KTLGTG+FG V LVK K +G +AMK+LDK+KVVKLKQVEHT+NEK+IL A+DFPFL+ + + FKDNS LY+V+++I GGEMF+H+R+ GRFSE +RFY AQ+VLAFEYLH+LD+IYRDLKPEN+LI + GY++ITDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK+KF +FS ELKD+L+ LLQ DLT+RYGNL+NGV DIKNHKWF G DWI ++ +++ P LPK + D SNFD YEEE IS EK EF +F
Sbjct: 2 SSSSNKKVQVKFFKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF-GSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 349
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 449.514 bits (1155), Expect = 1.292e-156 Identity = 221/342 (64.62%), Postives = 275/342 (80.41%), Query Frame = 2
Query: 143 DSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
D E+ E+ +R+ F +RW+NP+++ D F R+KTLGTG+FG V LVK K +G +AMK+LDK+KVVKLKQVEHT+NEK+IL A+DFPFL+ + + FKDNS LY+V+++I GGEMF+H+R+ GRFSE +RFY AQ+VLAFEYLH+LD+IYRDLKPEN+LI + GY++ITDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK+KF +FS ELKD+L+ LLQ DLT+RYGNL+NGV DIKNHKWF G DWI ++ +++ P LPK + D SNFD YEEE IS EK EF +F
Sbjct: 48 DPVEDFKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF-GSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 388
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0335495) HSP 1 Score: 446.047 bits (1146), Expect = 1.151e-155 Identity = 218/350 (62.29%), Postives = 278/350 (79.43%), Query Frame = 2
Query: 119 SSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
++ S+KK D+AE V E+ + +++ F ++W + + D F R+KTLGTG+FG V +V+ K T +AMK+LDK+KVVKLKQVEHT+NEK+IL A+ FPFL++L YHFKDNS LY+V++Y+ GGEMF+H+RK GRFSE +RFY AQ+VLAFEYLH LD+IYRDLKPEN+LI + GY+++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ +YEM +GYPPF ADQPIQIYEKIV GK++F +F +LKD+LR LLQ DLT+RYGNL+ GVNDIKN KWF DWI +F +++ P +P+ K DTSNFD YEEE IS+ EK EF +F
Sbjct: 5 ATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWF-ASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079852) HSP 1 Score: 446.047 bits (1146), Expect = 1.151e-155 Identity = 218/350 (62.29%), Postives = 278/350 (79.43%), Query Frame = 2
Query: 119 SSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
++ S+KK D+AE V E+ + +++ F ++W + + D F R+KTLGTG+FG V +V+ K T +AMK+LDK+KVVKLKQVEHT+NEK+IL A+ FPFL++L YHFKDNS LY+V++Y+ GGEMF+H+RK GRFSE +RFY AQ+VLAFEYLH LD+IYRDLKPEN+LI + GY+++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ +YEM +GYPPF ADQPIQIYEKIV GK++F +F +LKD+LR LLQ DLT+RYGNL+ GVNDIKN KWF DWI +F +++ P +P+ K DTSNFD YEEE IS+ EK EF +F
Sbjct: 5 ATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWF-ASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079851) HSP 1 Score: 446.047 bits (1146), Expect = 1.151e-155 Identity = 218/350 (62.29%), Postives = 278/350 (79.43%), Query Frame = 2
Query: 119 SSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
++ S+KK D+AE V E+ + +++ F ++W + + D F R+KTLGTG+FG V +V+ K T +AMK+LDK+KVVKLKQVEHT+NEK+IL A+ FPFL++L YHFKDNS LY+V++Y+ GGEMF+H+RK GRFSE +RFY AQ+VLAFEYLH LD+IYRDLKPEN+LI + GY+++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ +YEM +GYPPF ADQPIQIYEKIV GK++F +F +LKD+LR LLQ DLT+RYGNL+ GVNDIKN KWF DWI +F +++ P +P+ K DTSNFD YEEE IS+ EK EF +F
Sbjct: 5 ATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWF-ASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075529) HSP 1 Score: 311.997 bits (798), Expect = 4.090e-101 Identity = 139/285 (48.77%), Postives = 207/285 (72.63%), Query Frame = 2
Query: 314 KVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQF-PISNIEKHPAEFLD 1165
K AMK+L +V++LKQ+EH NE+ IL + PF+I+L + KD+S LY++ DY+ GGE+FT++R G+F+ + FY A++V A EYLH+L I+YRDLKPEN+LI +G+++ITDFGFAK+++ RTWTLCGTPEY+APEII KG+NK+VDWWALG+ IYEM GYPPF +QP IYEKI+ GK+++ ++ KD+++ LL D T+R GN++NG +D+K H+WF +W +++ +++ PPILP + DT NFD Y E+ + P +++ ++ +
Sbjct: 215 KYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFK-HLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKPAKAVDQRDLQYFN 498
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075528) HSP 1 Score: 312.383 bits (799), Expect = 2.513e-100 Identity = 139/285 (48.77%), Postives = 207/285 (72.63%), Query Frame = 2
Query: 314 KVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQF-PISNIEKHPAEFLD 1165
K AMK+L +V++LKQ+EH NE+ IL + PF+I+L + KD+S LY++ DY+ GGE+FT++R G+F+ + FY A++V A EYLH+L I+YRDLKPEN+LI +G+++ITDFGFAK+++ RTWTLCGTPEY+APEII KG+NK+VDWWALG+ IYEM GYPPF +QP IYEKI+ GK+++ ++ KD+++ LL D T+R GN++NG +D+K H+WF +W +++ +++ PPILP + DT NFD Y E+ + P +++ ++ +
Sbjct: 298 KYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFK-HLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKPAKAVDQRDLQYFN 581
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Zebrafish
Match: prkacbb (protein kinase, cAMP-dependent, catalytic, beta b [Source:ZFIN;Acc:ZDB-GENE-050904-4]) HSP 1 Score: 453.366 bits (1165), Expect = 2.039e-158 Identity = 225/352 (63.92%), Postives = 280/352 (79.55%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK + E V E+ +++ FL +W++P +S D F R KTLGTG+FG V LVK K + + +AMK+LDK+KVVKLKQVEHT+NEK+IL AV FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI +GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNLRNGVNDIKNHKWF DWI ++ ++V P +PK + DTSNFD YEEE +S EK EF +F
Sbjct: 1 MGNAATAKKGNELESVKEFLAKAKEDFLRKWESPQQSTTCLDDFDRQKTLGTGSFGRVLLVKHKASDQYYAMKVLDKQKVVKLKQVEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKNHKWF-ATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSVTEKCAKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Zebrafish
Match: prkacaa (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a [Source:ZFIN;Acc:ZDB-GENE-050114-6]) HSP 1 Score: 450.669 bits (1158), Expect = 1.875e-157 Identity = 223/353 (63.17%), Postives = 285/353 (80.74%), Query Frame = 2
Query: 113 MGSSHSSK-KTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++K K + E V E+ +++ FL++W+NP+++ S D F R+KTLGTG+FG V LVK K++G+ FAMK+LDK+KVVKLKQ+EHT+NEK+IL AV FPFL+ L + FKDN+ LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIK HKWF DWI ++ ++V P +PK K DTSNFD Y+EE+ +S EK EF +F
Sbjct: 1 MGNAPTAKNKGNEMESVKEFLAKAKEDFLKKWENPAQNTASLDHFERLKTLGTGSFGRVMLVKHKESGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKGHKWF-ATTDWIAIYQKKVEAPFIPKCKGPGDTSNFDDYDEEEIRVSITEKCGKEFAEF 352
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Zebrafish
Match: prkacab (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-040801-208]) HSP 1 Score: 447.588 bits (1150), Expect = 3.335e-156 Identity = 217/352 (61.65%), Postives = 282/352 (80.11%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++K+ + E V E+ +++ FL +W+NP+++ + F R+KTLGTG+FG V LV+ ++TG+ +AMK+L+K+KVVKLKQ+EHT+NEK+IL AV FPFL+ L Y FKDN+ LY+VM Y+ GGEMF+H+R+ GRFSE ARFY +Q+VL FEYLH LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ +YEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+RYGNL+NGVNDIK HKWF+ DWI ++ ++V P +PK + DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNTPAAKRGNEMESVKEFLAFAKEDFLRKWENPAQNTACLEDFDRLKTLGTGSFGRVMLVRHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNTNLYMVMQYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLMYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFS-TTDWIAIYQRRVEAPFVPKCRGPGDTSNFDDYEEEEIRVSFTEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351]) HSP 1 Score: 427.557 bits (1098), Expect = 1.030e-147 Identity = 216/337 (64.09%), Postives = 266/337 (78.93%), Query Frame = 2
Query: 158 VSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
+ E +++ FL +W+ KS D F ++KTLGTG+FG V LVK K + + FAMK+LDK KVVKLKQ+EHT+NEKKIL AV FPFL+ L FKDNS LY+VM YI GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK+++ +FS +LKD+LR LLQ DLT+R+GNL+NGV+DIKNH+WF DWI ++ ++V PI+PK + DTSNFD+Y+EE +S E+ EFLDF
Sbjct: 60 MKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWF-ASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEEVIRVSVSEQCSKEFLDF 395
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351]) HSP 1 Score: 427.557 bits (1098), Expect = 1.030e-147 Identity = 216/337 (64.09%), Postives = 266/337 (78.93%), Query Frame = 2
Query: 158 VSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
+ E +++ FL +W+ KS D F ++KTLGTG+FG V LVK K + + FAMK+LDK KVVKLKQ+EHT+NEKKIL AV FPFL+ L FKDNS LY+VM YI GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK+++ +FS +LKD+LR LLQ DLT+R+GNL+NGV+DIKNH+WF DWI ++ ++V PI+PK + DTSNFD+Y+EE +S E+ EFLDF
Sbjct: 60 MKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWF-ASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEEVIRVSVSEQCSKEFLDF 395
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 455.677 bits (1171), Expect = 3.613e-159 Identity = 223/352 (63.35%), Postives = 282/352 (80.11%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK E V E+ +++ FL++W+NP+++ +QF R+KTLGTG+FG V LV+ K+ G FAMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY +Q+VL FEYLH LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGV DIK HKWF+ DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF DF
Sbjct: 1 MGNAATAKKGGEIESVKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFS-TTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Xenopus
Match: prkacb (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:100038053]) HSP 1 Score: 455.292 bits (1170), Expect = 3.858e-159 Identity = 225/352 (63.92%), Postives = 280/352 (79.55%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK + E V E+ +++ FL +W+ P ++ S D F R+KTLGTG+FG V LVK K + +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+RYGNL+NGVNDIKNHKWF DWI ++ ++V P +PK + DTSNFD YEEE +S EK EF DF
Sbjct: 1 MGNAATAKKGNEIESVKEFLAKAKEDFLRKWETPPQNTASLDDFERIKTLGTGSFGRVMLVKHKGAEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSLTEKCAKEFADF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 445.662 bits (1145), Expect = 3.553e-155 Identity = 218/347 (62.82%), Postives = 276/347 (79.54%), Query Frame = 2
Query: 128 SSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
+S + + E+ +++ FL++W+NP+++ +QF R+KTLGTG+FG V LV+ K+ G FAMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY +Q+VL FEYLH LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGV DIK HKWF+ DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF DF
Sbjct: 12 TSSNAGLCKNMKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFS-TTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 357
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 443.736 bits (1140), Expect = 9.523e-155 Identity = 218/337 (64.69%), Postives = 273/337 (81.01%), Query Frame = 2
Query: 158 VSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
V E+ +++ FL++W+NP+++ +QF R+KTLGTG+FG V LV+ K+ G FAMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY +Q+VL FEYLH LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGV DIK HKWF+ DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF DF
Sbjct: 2 VKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFS-TTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 337
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 442.965 bits (1138), Expect = 1.957e-154 Identity = 217/337 (64.39%), Postives = 273/337 (81.01%), Query Frame = 2
Query: 158 VSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
+ E+ +++ FL++W+NP+++ +QF R+KTLGTG+FG V LV+ K+ G FAMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY +Q+VL FEYLH LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGV DIK HKWF+ DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF DF
Sbjct: 2 MKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFS-TTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 337
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592]) HSP 1 Score: 459.529 bits (1181), Expect = 7.377e-161 Identity = 225/352 (63.92%), Postives = 284/352 (80.68%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK E V E+ +++ FL++W+ PS++ DQF R+KTLGTG+FG V LVK K++G +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L + FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592]) HSP 1 Score: 449.899 bits (1156), Expect = 2.895e-157 Identity = 221/343 (64.43%), Postives = 278/343 (81.05%), Query Frame = 2
Query: 140 TDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
S+ +V E+ +++ FL++W+ PS++ DQF R+KTLGTG+FG V LVK K++G +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L + FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 2 ASSSNDVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 447.973 bits (1151), Expect = 2.403e-156 Identity = 222/352 (63.07%), Postives = 277/352 (78.69%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ +KK E V E+ +++ FL +W+NP S + F R KTLGTG+FG V LVK K T + +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGV+DIK HKWF DWI ++ ++V P +PK + DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNTAIAKKGSEVESVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWF-ATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 437.187 bits (1123), Expect = 2.988e-152 Identity = 217/337 (64.39%), Postives = 269/337 (79.82%), Query Frame = 2
Query: 158 VSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
V E+ +++ FL +W+NP S + F R KTLGTG+FG V LVK K T + +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGV+DIK HKWF DWI ++ ++V P +PK + DTSNFD YEEE+ +S EK EF +F
Sbjct: 3 VKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWF-ATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 338
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 437.958 bits (1125), Expect = 9.598e-152 Identity = 216/339 (63.72%), Postives = 270/339 (79.65%), Query Frame = 2
Query: 152 EEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
+ + E+ +++ FL +W+NP S + F R KTLGTG+FG V LVK K T + +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGV+DIK HKWF DWI ++ ++V P +PK + DTSNFD YEEE+ +S EK EF +F
Sbjct: 61 KSMKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWF-ATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 398
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. UniProt/SwissProt
Match: sp|P36887|KAPCA_PIG (cAMP-dependent protein kinase catalytic subunit alpha OS=Sus scrofa OX=9823 GN=PRKACA PE=1 SV=4) HSP 1 Score: 461.84 bits (1187), Expect = 6.483e-161 Identity = 228/352 (64.77%), Postives = 285/352 (80.97%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK E V E+ +++ FL++W+NP+++ DQF R+KTLGTG+FG V LVK K+TG FAMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. UniProt/SwissProt
Match: sp|P05132|KAPCA_MOUSE (cAMP-dependent protein kinase catalytic subunit alpha OS=Mus musculus OX=10090 GN=Prkaca PE=1 SV=3) HSP 1 Score: 459.529 bits (1181), Expect = 5.160e-160 Identity = 225/352 (63.92%), Postives = 284/352 (80.68%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK E V E+ +++ FL++W+ PS++ DQF R+KTLGTG+FG V LVK K++G +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L + FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. UniProt/SwissProt
Match: sp|P25321|KAPCA_CRIGR (cAMP-dependent protein kinase catalytic subunit alpha OS=Cricetulus griseus OX=10029 GN=PRKACA PE=1 SV=2) HSP 1 Score: 457.218 bits (1175), Expect = 3.642e-159 Identity = 225/352 (63.92%), Postives = 284/352 (80.68%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK E V E+ +++ FL++W++PS++ D F R+KTLGTG+FG V LVK K+TG +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L + FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. UniProt/SwissProt
Match: sp|P17612|KAPCA_HUMAN (cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens OX=9606 GN=PRKACA PE=1 SV=2) HSP 1 Score: 457.218 bits (1175), Expect = 3.931e-159 Identity = 225/352 (63.92%), Postives = 285/352 (80.97%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK E V E+ +++ FL++W++P+++ DQF R+KTLGTG+FG V LVK K+TG +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L + FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. UniProt/SwissProt
Match: sp|Q9MZD9|KAPCA_SHEEP (cAMP-dependent protein kinase catalytic subunit alpha OS=Ovis aries OX=9940 GN=PRKACA PE=1 SV=3) HSP 1 Score: 456.833 bits (1174), Expect = 5.514e-159 Identity = 225/352 (63.92%), Postives = 284/352 (80.68%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK E V E+ +++ FL++W+NP+++ DQF R+KTLGTG+FG V LVK +TG +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV+FPFL+ L + FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. TrEMBL
Match: H3ADK9 (Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a OS=Latimeria chalumnae OX=7897 GN=LOC102362951 PE=3 SV=1) HSP 1 Score: 466.077 bits (1198), Expect = 3.309e-160 Identity = 228/352 (64.77%), Postives = 285/352 (80.97%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK E V E+ +++ FL RW+NP+++ S DQF R+KTLGTG+FG V LVK+KD G+ +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV FPFL+TL Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIK HKWF+ DWI ++ ++V P +PK DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNTATAKKGGEQESVKEFLAKAKEDFLRRWENPAQNTASLDQFERIKTLGTGSFGRVMLVKQKDAGQHYAMKILDKQKVVKLKQIEHTLNEKRILQAVTFPFLVTLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDRRGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFS-TTDWIAIYQRKVEAPFIPKFTGPGDTSNFDDYEEEEIRVSLTEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. TrEMBL
Match: A0A2R5LNS5 (Hipothetical protein OS=Ornithodoros turicata OX=34597 PE=3 SV=1) HSP 1 Score: 466.077 bits (1198), Expect = 4.443e-160 Identity = 228/352 (64.77%), Postives = 287/352 (81.53%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK D AE V ++ + ++K+F ++W++PS + + D F R+KTLGTG+FG V LV+ K FAMK+LDK+KVVKLKQVEHT+NEK+IL AVDFPFL+ L +HFKDNS LY+V++Y+ GGEMF+H+RK GRFSE ARFYGAQ+VLAF+YLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ +YEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ + + P +PK K DTSNFD+YEEE IS+ EK EF DF
Sbjct: 1 MGNAATTKKGDPAENVEKFLEEAKKSFEQKWNSPSSNTATLDDFDRMKTLGTGSFGRVMLVQHKQNKDYFAMKILDKQKVVKLKQVEHTLNEKRILQAVDFPFLVRLAFHFKDNSNLYMVLEYVLGGEMFSHLRKSGRFSEPHARFYGAQIVLAFQYLHSLDLIYRDLKPENLLIDNTGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYKKDIEAPFIPKCKGPGDTSNFDEYEEEPLRISSTEKCAKEFADF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. TrEMBL
Match: A0A131YC20 (Protein kinase A OS=Rhipicephalus appendiculatus OX=34631 PE=3 SV=1) HSP 1 Score: 464.537 bits (1194), Expect = 1.429e-159 Identity = 228/352 (64.77%), Postives = 286/352 (81.25%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK D AE V + + +RK+F ++W NPS + S D F R+KTLGTG+FG V LV+ K +AMK+LDK+KVVKLKQVEHT+NEK+IL AV+FPFL+ L YHFKDNS LY+V++Y+ GGEMF+H+RK GRFSE ARFYGAQ+VLAF+YLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ +YEM +GYPPF ADQPIQIYEKIV GK++F +F+ +LKD+LR LLQ DLT+R+GNL+NGVNDIKNH+WF DWI ++ ++V P +PK K DTSNFD+YEEE IS+ EK EF +F
Sbjct: 1 MGNAATTKKGDPAENVERFLEEARKSFEQKWSNPSSNTASLDDFDRIKTLGTGSFGRVMLVQHKQHKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAVEFPFLVKLAYHFKDNSNLYMVLEYVLGGEMFSHLRKSGRFSEPHARFYGAQIVLAFQYLHSLDLIYRDLKPENLLIDHTGYIKVTDFGFAKRVRGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHRWF-ATTDWIAIYKKEVEAPFVPKCKGPGDTSNFDEYEEEALRISSTEKCAREFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. TrEMBL
Match: A0A224Z516 (Protein kinase A OS=Rhipicephalus zambeziensis OX=60191 PE=3 SV=1) HSP 1 Score: 464.537 bits (1194), Expect = 1.778e-159 Identity = 228/352 (64.77%), Postives = 286/352 (81.25%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK D AE V + + +RK+F ++W NPS + S D F R+KTLGTG+FG V LV+ K +AMK+LDK+KVVKLKQVEHT+NEK+IL AV+FPFL+ L YHFKDNS LY+V++Y+ GGEMF+H+RK GRFSE ARFYGAQ+VLAF+YLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ +YEM +GYPPF ADQPIQIYEKIV GK++F +F+ +LKD+LR LLQ DLT+R+GNL+NGVNDIKNH+WF DWI ++ ++V P +PK K DTSNFD+YEEE IS+ EK EF +F
Sbjct: 1 MGNAATTKKGDPAENVERFLEEARKSFEQKWTNPSSNTASLDDFDRIKTLGTGSFGRVMLVQHKQHKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAVEFPFLVKLAYHFKDNSNLYMVLEYVLGGEMFSHLRKSGRFSEPHARFYGAQIVLAFQYLHSLDLIYRDLKPENLLIDHTGYIKVTDFGFAKRVRGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHRWF-ATTDWIAIYKKEVEAPFVPKCKGPGDTSNFDEYEEEALRISSTEKCAREFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. TrEMBL
Match: A0A4D5RAW4 (Hipothetical protein (Fragment) OS=Ixodes scapularis OX=6945 PE=3 SV=1) HSP 1 Score: 464.151 bits (1193), Expect = 2.414e-159 Identity = 227/352 (64.49%), Postives = 287/352 (81.53%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK D AE V + + +++ F ++W++P+ + + D F RVKTLGTG+FG V LV+ K+ +AMK+LDK+KVVKLKQVEHT+NEK+IL AVDFPFL+ L YHFKDNS LY+V++Y+ GGEMF+H+RK GRFSE ARFYGAQ+VLAF+YLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ +YEM +GYPPF ADQPIQIYEKIV GK++F +F+ +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V P +PK K DTSNFD+YEEE IS+ EK EF DF
Sbjct: 1 MGNAATTKKGDPAENVERFLEDAKRVFEQKWNSPATNTATLDDFDRVKTLGTGSFGRVMLVQHKEKKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAVDFPFLVRLAYHFKDNSNLYMVLEYVLGGEMFSHLRKSGRFSEPHARFYGAQIVLAFQYLHSLDLIYRDLKPENLLIDHTGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYKKEVEAPFIPKCKGPGDTSNFDEYEEEALRISSTEKCAKEFADF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Cavefish
Match: ENSAMXT00000050353.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308]) HSP 1 Score: 459.144 bits (1180), Expect = 7.051e-161 Identity = 227/352 (64.49%), Postives = 285/352 (80.97%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK + E V E+ +++ FL +W+ P +S D F R+KTLGTG+FG V LVK K T + +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE+ ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI +GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V PI+PK + DTSNFD YEEE+ IS+ EK EFL+F
Sbjct: 1 MGNAAAAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEEEIRISDTEKCAKEFLEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Cavefish
Match: prkacbb (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:103034112]) HSP 1 Score: 454.907 bits (1169), Expect = 3.149e-159 Identity = 226/352 (64.20%), Postives = 281/352 (79.83%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK + E V E+ +++ FL +W+ P +S + D F R+KTLGTG+FG V LVK K T + FAMK+LDK+KVVKLKQ+EHT+NEK+IL AV FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI +GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+RYGNL+NGVNDIKNHKWF DWI ++ ++V P +PK + DTSNFD YEEE +S EK EF +F
Sbjct: 1 MGNAAAAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTTLDDFERLKTLGTGSFGRVMLVKHKGTEQFFAMKVLDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWF-ATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSVTEKCAKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Cavefish
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103024963]) HSP 1 Score: 454.907 bits (1169), Expect = 4.285e-159 Identity = 226/353 (64.02%), Postives = 286/353 (81.02%), Query Frame = 2
Query: 113 MGSSHSSK-KTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++K K + E V E+ +++ FL++W+NP+++ S DQF R+KTLGTG+FG V LVK K+TG+ FAMK+LDK+KVVKLKQ+EHT+NEK+IL AV FPFL+ L + FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGV+DIK HKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAPTAKNKGNEMESVKEFLAKAKEDFLKKWENPAQNTASLDQFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKGHKWF-ATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFTEKCGKEFAEF 352
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Cavefish
Match: ENSAMXT00000050990.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308]) HSP 1 Score: 452.981 bits (1164), Expect = 3.120e-158 Identity = 224/348 (64.37%), Postives = 281/348 (80.75%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAE 1156
MG++ ++KK + E V E+ +++ FL +W+ P +S D F R+KTLGTG+FG V LVK K T + +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE+ ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI +GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF DWI ++ ++V PI+PK + DTSNFD YEEE+ IS+ EK E
Sbjct: 1 MGNAAAAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEEEIRISDTEKLRGE 347
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Cavefish
Match: prkacab (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103023241]) HSP 1 Score: 446.432 bits (1147), Expect = 7.304e-156 Identity = 217/352 (61.65%), Postives = 281/352 (79.83%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++K+ + E V E+ +R+ FL +W+ P+++ S DQF +KTLGTG+FG V LV+ ++ G+ +AMK+L+K+KVVKLKQ+EHT+NEK+IL AV FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY +Q+VL FEYLH LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ +YEM +GYPPF ADQPI IYEKIV GK++F +FS +LK++LR LLQ DLT+RYGNL+NGVNDIK HKWF+ DWI ++ ++V P +PK + DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNTPAAKRGNEMESVREFLALAREDFLRKWETPAQNTASLDQFDLLKTLGTGSFGRVMLVRHRENGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEYSFKDNSNLYMVMEYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIHIYEKIVSGKVRFPSHFSSDLKELLRNLLQVDLTKRYGNLKNGVNDIKGHKWFS-TTDWIAIYQRRVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCGKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 416.772 bits (1070), Expect = 9.423e-146 Identity = 192/289 (66.44%), Postives = 236/289 (81.66%), Query Frame = 2
Query: 302 KDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
+ G+ ++K + KVVKLKQVEHT+NEK+IL A+ FPFL+ L Y FKDNS LY+V++Y+ GGEMF+H+R+ GRFSE +RFY AQ+VLAFEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF+ DWI ++ ++V P +PK K D SNFD YEEE+ IS+ EK EF DF
Sbjct: 1 EQVGQHVSLKATKRTKVVKLKQVEHTLNEKRILQAISFPFLVRLEYSFKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFS-TTDWIAIYQRKVEAPFIPKCKGPGDASNFDDYEEEEIRISSTEKCAKEFADF 288
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002200.1 (pep scaffold:Pmarinus_7.0:GL479132:31244:36905:-1 gene:ENSPMAG00000001993.1 transcript:ENSPMAT00000002200.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 228.794 bits (582), Expect = 1.609e-71 Identity = 112/276 (40.58%), Postives = 170/276 (61.59%), Query Frame = 2
Query: 302 KDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQ-GR-TWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLG--KMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEE 1117
KD+ FA+K L K+ VV+ +Q EH +EK+IL PF++ F+D +++++M+ GGE+++ +R G F E ARF A VV A YLH I+YRDLKPEN+L+ GYI++ DFGFAK++ GR WT CGTPEY+ PE+I+ +G+++ D WALG+ +YE+ +G PPF P++ Y I+ G ++ F +DI+R L + + + R GN ++GV D++ HKWF G DW L Q+ P+ ++ D NFD + E+
Sbjct: 54 KDSDVTFALKCLKKKFVVESRQQEHVYSEKRILQECSCPFIVRFYRTFRDQKFVFLLMEACLGGELWSVLRDSGGFQEVSARFCVACVVEALAYLHARGILYRDLKPENLLLDARGYIKMADFGFAKKLACGRKAWTFCGTPEYVCPEMIVNRGHDRGADCWALGVLVYELLAGVPPFSGTDPMKTYNAILWGMERVHFPNEVGKRAEDIIRRLCRQNPSERLGNQKHGVGDVRKHKWFQGF-DWESLRSNQLASPLKREVSGPTDFKNFDWFPED 328
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008480.1 (pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1 gene:ENSPMAG00000007654.1 transcript:ENSPMAT00000008480.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 214.157 bits (544), Expect = 2.586e-64 Identity = 112/293 (38.23%), Postives = 172/293 (58.70%), Query Frame = 2
Query: 299 EKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHN-LDIIYRDLKPENVLIGTNGYIRITDFGFAKR--IQGRTW-TLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLD 1165
EK TG+ +AMK+L KE +V +V HT+ E ++L PFL L Y F+ + L VM+Y+ GGE+F H+ + FSE+ RFYGA++V A +YLH +++YRDLK EN+++ +G+I+I DFG K G T T CGTPEYLAPE++ Y ++VDWW LG+ +YEM G PF +++E I++ ++F + S + + +L LL+ D +R G + +I H +F G W +++ +++ PP P++ S DT FD E+F I P + D
Sbjct: 169 EKATGQYYAMKILKKEVIVAKDEVAHTLTENRVLQTTKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGII-WQDVYDRKMTPPFKPQVASETDTRYFD----EEFTAQTITITPPDRFD 456
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004852.1 (pep scaffold:Pmarinus_7.0:GL488704:3417:7135:1 gene:ENSPMAG00000004407.1 transcript:ENSPMAT00000004852.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 197.593 bits (501), Expect = 1.200e-61 Identity = 103/168 (61.31%), Postives = 137/168 (81.55%), Query Frame = 2
Query: 158 VSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRI 661
V E+ +++ FL++W+NP ++ D F R+KTLGTG+FG V LVK K T + FAMK+LDK+KVVKLKQVEHT+NEK+IL A+ FPFL++L Y +KDNS LY+V++Y+ GGEMF+H+R+ GRFSE +RFY AQ+VLAFEYLH+LD+IYRDLKPEN+LI GYI++
Sbjct: 16 VKEFLAKAKEDFLKKWENPQQNTSCLDDFERMKTLGTGSFGRVMLVKHKATDRYFAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVSLEYSYKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQV 183
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006766.1 (pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 gene:ENSPMAG00000006086.1 transcript:ENSPMAT00000006766.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 205.297 bits (521), Expect = 1.514e-61 Identity = 106/272 (38.97%), Postives = 162/272 (59.56%), Query Frame = 2
Query: 299 EKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKIL-DAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKR---IQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFD 1102
K G +A+K++ K +++ K+ +H + E+ +L V PFL+ L+Y F+ LY VMDY+ GGE+F H+++ G F E+ A+FY A++ A YLH+L+I+YRDLKPEN+L+ G+I +TDFG K T T CGTPEYLAPE++ Y+++VDWW LG +YEM G PPF + Q+YE I+ ++ + +L LL D +R G + + +IKNH +F+ +W +L +++P P P + D NFD
Sbjct: 111 HKSDGIFYAVKVMKKSIILQKKEEKHIMAERNVLVKNVRHPFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILHQPLQLRPCTTNAAISVLEGLLHKDPHQRLGATSD-ILEIKNHVFFS-TINWNDLDAKRIPSPYNPGVSGPCDLHNFD 380
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]) HSP 1 Score: 298.901 bits (764), Expect = 1.798e-98 Identity = 144/272 (52.94%), Postives = 196/272 (72.06%), Query Frame = 2
Query: 311 GKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKS-IDDTSNFDKYEEEQF 1123
G+ +A+K+L K++VVK+KQVEHT +E+++L V+ PFLI + F+D +++VMDYI GGE+F+ +RK RF A+FY A+V+LA EYLH +IIYRDLKPEN+L+ NG+I+ITDFGFAK +Q TWTLCGTP+Y+APE+I K YNKSVDWW+LG+ IYEM +GY PF P++ YEKI+ GK+ + YF ++ D+L L+ DLTRR GNL++G DIK H WF+ + W L + + P P + S I DTS FD+Y EEQ
Sbjct: 93 GRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFS-EVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQL 363
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 286.574 bits (732), Expect = 2.415e-93 Identity = 135/272 (49.63%), Postives = 191/272 (70.22%), Query Frame = 2
Query: 311 GKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKM-KSIDDTSNFDKYEEEQF 1123
G+ +A+K L K +VKLKQVEHT +E+++L V PF+I + F+D+ +++VMDYI GGE+F+ +RK RF A+FY A+V LA EYLH+ DIIYRDLKPEN+L+ NG+I+ITDFGFAK + T+TLCGTP+Y+APE++ K YNKSVDWW+ G+ IYEM +GY PF ++ YE I+ ++KF +F + +D+L+ L+ DL+ R GNL+NG D+KNH WFN + W +L + + P P + + DTS FD+Y EE+F
Sbjct: 111 GRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFN-EVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEEF 381
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 285.804 bits (730), Expect = 3.416e-93 Identity = 136/273 (49.82%), Postives = 192/273 (70.33%), Query Frame = 2
Query: 302 KDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKM-KSIDDTSNFDKYEEE 1117
+ G+ +AMK+L KE VV+LKQVEHT +E+ +L V PF+I + F+D ++++MDYI GGE+F+ +RK RF A+FY A+V LA EYLH+ DIIYRDLKPEN+L+ NG+I+ITDFGFAK + T+TLCGTP+Y+APE++ K YNKS+DWW+ GI IYEM +GY PF ++ YEKI+ +++F +F+ ++KD+L L+ DL++R GNL+NG D+KNH WF + W +L + + P P + + DTS FDKY EE
Sbjct: 107 RHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFK-EVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEE 378
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]) HSP 1 Score: 241.121 bits (614), Expect = 5.917e-73 Identity = 120/283 (42.40%), Postives = 179/283 (63.25%), Query Frame = 2
Query: 299 EKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAK---RIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNI 1138
+KDT KV+A+K + K +V +V HT+ E+ +L VD PF++ L + F+ LY V+ +I GGE+F H++K GRF + ARFY A+++ A + LH LD++YRDLKPEN+L+ G+I + DFG K + +T T CGTPEYLAPE++L GY K+VDWW LG+ +YEM +G PP+ + ++Y+KI+ + F F + KD+L LL D TRR G NG ++I+NH +F+ + W L + PP P + + DTSNFD+ + PI ++
Sbjct: 366 KKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLG--YNGADEIRNHPFFS-QLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSV 645
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]) HSP 1 Score: 238.424 bits (607), Expect = 6.464e-72 Identity = 122/283 (43.11%), Postives = 179/283 (63.25%), Query Frame = 2
Query: 299 EKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAK---RIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNI 1138
+KDT K++A+K L K +V +V HT+ E+ +L VD PF++ L + F+ LY+V+ +I GGE+F H++ GRFS +RFY A+++ A + LH LD+IYRDLKPEN+L+ G+I + DFG K + +T T CGTPEYLAPEI+L +GY K+VDWW LGI +YEM +G PP+ + +Y+KI+ + F F KD+L LL D +RR G NG ++I+NH +F W +L + PP P +KS DT+NFD+ ++ PI ++
Sbjct: 363 KKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLG--VNGTDEIRNHPFFK-DISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSV 642
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Nematostella
Match: EDO35228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM62]) HSP 1 Score: 298.901 bits (764), Expect = 1.049e-98 Identity = 142/294 (48.30%), Postives = 206/294 (70.07%), Query Frame = 2
Query: 299 EKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYF-SVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQF---PISNIEKHPAEFLDF 1168
++ G+ +A+K+++ +V++LKQVEH NEK IL +++ PF++ L + D ++LY++++Y GGE+FT++R GRF+ F+G+++V A +YLH I+YRDLKPEN+L+ +G++++TDFGFAK + +TWTLCGTPEYLAPEII KG+NK+VDWWALGI IYEM GYPPF D P IYEKI+ GK+++ ++ + KD+++ LL D TRR G+++NG D+KNHKWF DW + +++ PPI PK+ DT NFD Y EE + P N KH F DF
Sbjct: 37 DRRGGEFYALKIMNISEVIRLKQVEHVQNEKNILMSIEHPFIVNLLWTQHDQTFLYMLLEYACGGELFTYLRTAGRFNNGTGLFFGSEIVSAMDYLHGHSIVYRDLKPENILLDRDGHVKLTDFGFAKEVHDKTWTLCGTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEKILSGKVEWPKHMDNTSAKDLIKKLLVHDRTRRLGSMKNGSEDVKNHKWFK-VIDWNLVLQRKLKPPINPKISHPGDTRNFDDYPEEDWRGAPPLN-AKHLEPFKDF 328
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Nematostella
Match: EDO41166 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S521]) HSP 1 Score: 230.72 bits (587), Expect = 4.539e-71 Identity = 111/278 (39.93%), Postives = 166/278 (59.71%), Query Frame = 2
Query: 314 KVFAMKMLDKEKVVK-LKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRI---QGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISN 1135
K+FAMK+L K +++ K HT E+ IL+ V PF++ L Y F+ LY++++Y+ GGE+F + + G F E+ A FY +++ +A E+LH I+YRDLKPEN+L+ NG++++TDFG K T T CGT EY+APEI+ G+ K+VDWW+LG +Y+M +G PPF AD + +KI+ GK+ Y + E KD +R LL+ R G + N IK H +F C W +L ++V PP P + +D S FD Q P+ +
Sbjct: 92 KIFAMKVLKKAAIIRSQKDTAHTKAERNILECVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFLEDTACFYLSEISMALEHLHKQGIVYRDLKPENILLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMYDMLTGTPPFCADNRKKTIDKILKGKLIIPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHIC-WEDLLAKKVEPPFRPSISGEEDVSQFDSKFTRQTPVDS 368
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Nematostella
Match: EDO38407 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCZ7]) HSP 1 Score: 231.491 bits (589), Expect = 4.683e-69 Identity = 115/266 (43.23%), Postives = 174/266 (65.41%), Query Frame = 2
Query: 314 KVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQ-GR-TWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLG--KMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNF 1099
+ FA+K L K +V+ +Q +H ++EKKI+ + PF++ L+ FKD YLY++++ GGE++T +R G F ++ RFY V+ AF+YLH+ I+YRDLKPEN+L+ +GY ++ DFGFAK+I GR TWT CGTPEY+APEIIL KG++ S D+W+LGI +YE+ +G PPF P++ Y I+ G + F + + +++ L + + R G + G+ DI HKWF+G +W L +++ PI PK+KS D SNF
Sbjct: 376 RTFALKTLKKHHIVETRQQDHIMSEKKIMMESNSPFIVRLHKTFKDKKYLYMLLEVCLGGELWTILRDRGSFDDSTTRFYVGCVIEAFQYLHSKGIVYRDLKPENLLLDGHGYCKLVDFGFAKKIGFGRKTWTFCGTPEYVAPEIILNKGHDLSADYWSLGILMYELLTGSPPFSGTDPMKTYNIILKGIDMIDFPRKITRNAHALIKKLCRDNPVERLGYQKGGLKDIMKHKWFDG-FNWDGLRSRKLNSPIAPKIKSPVDASNF 640
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2]) HSP 1 Score: 218.779 bits (556), Expect = 1.110e-66 Identity = 127/335 (37.91%), Postives = 190/335 (56.72%), Query Frame = 2
Query: 110 AMGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKIL-DAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKR---IQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFD 1102
++ + +++ D E+ K L +NP + P F+ +K +G G+FG VFL K K K +A+K+L+K + K + +H + E+ +L V PFL+ L+Y F+ LY V+DY+ GGE+F H+++ F E+ ARFY A++ A YLH L IIYRDLKPEN+L+ + G+I +TDFG K G T T CGTPEYLAPE++ + Y+KSVDWW LG +YEM G PPF + ++Y+ I+ ++ S + IL LLQ D T+R G+ DI+ H +F +W +L + + PP P + D +FD
Sbjct: 33 SLDNPKNAQANDEDEQPGSDDADVEKIDLGESNNP---KAKPSDFLFLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVTHPFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDFGLCKEGIDRSGTTSTFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRS-INWQQLVARGIEPPYNPNVSGQLDLKHFD 363
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Nematostella
Match: EDO39163 (Ribosomal protein S6 kinase [Source:UniProtKB/TrEMBL;Acc:A7SAZ2]) HSP 1 Score: 213.386 bits (542), Expect = 9.456e-62 Identity = 106/278 (38.13%), Postives = 174/278 (62.59%), Query Frame = 2
Query: 311 GKVFAMKMLDKEKVV-KLKQVEHTVNEKKILDAVD-FPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQG-----RTWTLCGTPEYLAPEIIL--CKGYNKSVDWWALGIFIYEMTSGYPPFVAD----QPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDK 1105
G++FAMK+L K +V K K EHT E+++L+AV PFL+TL++ F+ + L+++MDY+ GGE+FTH+ + +F+E+ R Y ++V+A ++LH L IIYRD+K EN+L+ +G++ +TDFG +K R ++ CGT EY+APE++ +G++K+VDWW+LG+ +YE+ +G PF D +I ++I+ S E D+L LLQ D +R G G +++K H +F DW +L +++P P P+++ D SNF +
Sbjct: 42 GRLFAMKVLKKATIVQKAKTAEHTRTERQVLEAVRRCPFLVTLHWAFQTEAKLHLIMDYVNGGELFTHLYQREKFTEDEVRLYIGEIVVALDHLHQLGIIYRDIKLENILLDKDGHVVLTDFGLSKEFAAPNSGERAYSFCGTIEYMAPEVVKGGSRGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQSEISKRILHNNPPMPHDLSAEAIDLLHKLLQKDPKKRLGA--KGAHELKAHPFFKA-FDWADLAEKRIPAPFKPRIRDELDVSNFSE 316 HSP 2 Score: 122.865 bits (307), Expect = 6.701e-30 Identity = 90/309 (29.13%), Postives = 155/309 (50.16%), Query Frame = 2
Query: 308 TGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTN---GYIRITDFGFA--KRIQGRTWTLCGTPEYLAPEI----ILCKGYNKSVDWWALGIFIYEMTSGYPPFVA------DQPIQIYEKIVLGKMKFN----QYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQ-VPPPILPKMK-------SIDDTSN-FDKYEEEQFPISNIEKHP 1150
+G+ +A+K++ + + +HT + + P ++TL ++D + Y+VM+ + GGE+ IRK F+E+ A ++V A E++H +++RDLKPEN+L N I+I DFGFA K + T C T Y APE+ + GY++S D W+LG+ +Y M SG PF + + ++I G ++F+ Q S + KD+++ LL D ++R V ++ H W + L H V P IL + K +++ T N F+K + + F + ++E P
Sbjct: 418 SGQEYAVKIISR-------RCDHTREVQSLKMCHGHPNIVTLYDVYQDEFHTYLVMELLAGGELLERIRKKKMFTESAASVIMRKIVSAVEFMHQRGVVHRDLKPENLLFVDNSEDAEIKIVDFGFACVKPEAQQLQTPCFTLSYAAPEVLDQTVSNSGYDESCDLWSLGVILYTMLSGQVPFQSSGSWYKSSTGFVMQRITQGDVRFDGQQWQSISPQAKDLIQGLLTVDPSQRL-----TVQEVLRHDWLRVETS---LPHTPLVTPGILERGKKRTYVESALNVTYNAFNKAQRQGFTLMDVENAP 711
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Medaka
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101163742]) HSP 1 Score: 457.988 bits (1177), Expect = 1.955e-160 Identity = 225/352 (63.92%), Postives = 283/352 (80.40%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK + E V E+ +++ FL++W+NP++ + D F R+KTLGTG+FG V LVK K+TG+ FAMK+LDK+KVVKLKQ+EHT+NEK+IL AV FPFL+ L + FKD S LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNLRNGVNDIK HKWF DWI ++ ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNTPTAKKGNEVESVKEFLAKAKEDFLKKWENPAQQTAALDHFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEHSFKDTSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKGHKWF-ATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Medaka
Match: ENSORLT00000040218.1 (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101160964]) HSP 1 Score: 454.907 bits (1169), Expect = 3.686e-159 Identity = 222/352 (63.07%), Postives = 284/352 (80.68%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ +++K + E V E+ +++ FL++W+NPS++ + +QF R+KTLGTG+FG V LVK ++TG+ +AMK+L+K+KVVKLKQ+EHT+NEK+IL AV FPFL+ L + FKDN+ LY+VM+Y+ GGEMF+H+RK GRFSE ARFY Q+VL FEYLH LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ +YEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+RYGNL+NGVNDIK HKWF DWI +F ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAPTARKGNEMESVKEFLAKAKEDFLKKWENPSQNTANLEQFERLKTLGTGSFGRVMLVKHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEFSFKDNTNLYMVMEYVPGGEMFSHLRKIGRFSEPHARFYATQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWF-AATDWIAIFQKKVEAPFVPKFKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Medaka
Match: ENSORLT00000007944.2 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:101160305]) HSP 1 Score: 453.366 bits (1165), Expect = 1.540e-158 Identity = 224/352 (63.64%), Postives = 281/352 (79.83%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK + E V E+ +++ FL +W+ P + S D F R KTLGTG+FG V LVK K T + +AMK+LDK+KVVKLKQ+EHT+NEK+IL AV FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE+ ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI +GYI++TDFGFAK+++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+R+GNL+NGVNDIKNHKWF+ DWI ++ +++ P LPK + DTSNFD YEEE +S EK EF DF
Sbjct: 1 MGNTATAKKGNEQESVKEFLAKAKEDFLRKWECPPQCTTSLDDFERFKTLGTGSFGRVMLVKHKATNQFYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLVYAFKDNSNLYMVMEYVPGGEMFSHLRRTGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKKVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFS-TTDWIAIYERKIEAPFLPKCRGPGDTSNFDDYEEEDIHVSQTEKCGKEFADF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Medaka
Match: ENSORLT00000033457.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876]) HSP 1 Score: 449.899 bits (1156), Expect = 3.649e-157 Identity = 223/352 (63.35%), Postives = 280/352 (79.55%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ ++KK + E V E+ +++ FL +W+ P +S + F R+KTLGTG+FG V LVK K + + FAMK+LDK+KVVKLKQ+EHT+NEK+IL AV FPFL+ L Y FKDNS LY+VM+Y+ GGEMF+H+R+ GRFSE ARFY AQ+VL FEYLH+LD+IYRDLKPEN+LI +GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+RYGNL+NGVNDIK HKWF DWI ++ ++V P +PK + DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAATAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWF-ATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Medaka
Match: ENSORLT00000018528.2 (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101160964]) HSP 1 Score: 447.588 bits (1150), Expect = 3.932e-156 Identity = 222/360 (61.67%), Postives = 284/360 (78.89%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSR--------GSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG++ +++K + E V E+ +++ FL++W+NPS+ + + +QF R+KTLGTG+FG V LVK ++TG+ +AMK+L+K+KVVKLKQ+EHT+NEK+IL AV FPFL+ L + FKDN+ LY+VM+Y+ GGEMF+H+RK GRFSE ARFY Q+VL FEYLH LD+IYRDLKPEN+LI GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ +YEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+RYGNL+NGVNDIK HKWF DWI +F ++V P +PK K DTSNFD YEEE+ +S EK EF +F
Sbjct: 1 MGNAPTARKGNEMESVKEFLAKAKEDFLKKWENPSQGQDFFQFANTANLEQFERLKTLGTGSFGRVMLVKHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEFSFKDNTNLYMVMEYVPGGEMFSHLRKIGRFSEPHARFYATQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWF-AATDWIAIFQKKVEAPFVPKFKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 359
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Planmine SMEST
Match: SMESG000063155.1 (SMESG000063155.1) HSP 1 Score: 694.886 bits (1792), Expect = 0.000e+0 Identity = 352/352 (100.00%), Postives = 352/352 (100.00%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRVKTLGTGTFGTVFLVKEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF
Sbjct: 1 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRVKTLGTGTFGTVFLVKEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 352
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Planmine SMEST
Match: SMESG000000892.1 (SMESG000000892.1) HSP 1 Score: 447.588 bits (1150), Expect = 1.960e-156 Identity = 226/352 (64.20%), Postives = 281/352 (79.83%), Query Frame = 2
Query: 113 MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
MG + S K+ + EV E+ +++R+ F ++WD P + + +F RVKTLGTGTFGTV LV + T +AMK+L+K+K+VK+KQVEHT+NEK+IL AV+FPFL+ L+Y FKDNSYLY+V++Y+ GGEMF+H+RK GR+SE A FY +QVV+ FEYLH LDI+YRDLKPEN+LI NGYI+ITDFGFAKRI+GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALGI IYEM GYPPF+ADQPI IYEKIV+GK KF Y S + KD++R LLQ+DLT+RYGNL+NGV DIKNHKWF G DWI ++ +++ PP P++KSI DTS FD Y+EE IS EK EFLDF
Sbjct: 1 MGINTSKKENNC--EVEEFLENARQEFFDKWDLPVHNNATLAEFTRVKTLGTGTFGTVILVYKPQTDTYYAMKVLNKQKIVKMKQVEHTLNEKRILQAVNFPFLVNLHYSFKDNSYLYLVLEYVVGGEMFSHLRKSGRYSECQANFYASQVVMTFEYLHYLDIVYRDLKPENILINKNGYIKITDFGFAKRIKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGILIYEMIVGYPPFIADQPIHIYEKIVIGKFKFPNYVSPDAKDLIRCLLQSDLTKRYGNLKNGVADIKNHKWFYGNSDWINIYKEKILPPFKPELKSIGDTSYFDDYDEEPLKISKREKCAKEFLDF 350
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Planmine SMEST
Match: SMESG000000892.1 (SMESG000000892.1) HSP 1 Score: 446.817 bits (1148), Expect = 3.374e-156 Identity = 225/348 (64.66%), Postives = 281/348 (80.75%), Query Frame = 2
Query: 125 HSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
++SKK ++ EE E+ +++R+ F ++WD P + + +F RVKTLGTGTFGTV LV + T +AMK+L+K+K+VK+KQVEHT+NEK+IL AV+FPFL+ L+Y FKDNSYLY+V++Y+ GGEMF+H+RK GR+SE A FY +QVV+ FEYLH LDI+YRDLKPEN+LI NGYI+ITDFGFAKRI+GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALGI IYEM GYPPF+ADQPI IYEKIV+GK KF Y S + KD++R LLQ+DLT+RYGNL+NGV DIKNHKWF G DWI ++ +++ PP P++KSI DTS FD Y+EE IS EK EFLDF
Sbjct: 4 NTSKKENNCEE--EFLENARQEFFDKWDLPVHNNATLAEFTRVKTLGTGTFGTVILVYKPQTDTYYAMKVLNKQKIVKMKQVEHTLNEKRILQAVNFPFLVNLHYSFKDNSYLYLVLEYVVGGEMFSHLRKSGRYSECQANFYASQVVMTFEYLHYLDIVYRDLKPENILINKNGYIKITDFGFAKRIKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGILIYEMIVGYPPFIADQPIHIYEKIVIGKFKFPNYVSPDAKDLIRCLLQSDLTKRYGNLKNGVADIKNHKWFYGNSDWINIYKEKILPPFKPELKSIGDTSYFDDYDEEPLKISKREKCAKEFLDF 349
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 434.106 bits (1115), Expect = 8.180e-149 Identity = 213/339 (62.83%), Postives = 271/339 (79.94%), Query Frame = 2
Query: 152 EEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
+ V + + +++ F+E+WD PS++ F R++TLGTG+FG V LV+ K T + A+K+LDK+KVVKLKQVEHT+NEK+IL A+ F FL+ L+YHFKDNS LY+V++++ GGEMF+H+R+ GRFSE +RFY AQ+VLAFEYLH LD+IYRDLKPEN+LI + GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+RYGNL+N V DIK HKWF CDWI +F +++ P +P +K D+SNFD YEEE I+N EK EF DF
Sbjct: 170 DSVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLN-CDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 507
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 432.18 bits (1110), Expect = 4.443e-147 Identity = 212/337 (62.91%), Postives = 270/337 (80.12%), Query Frame = 2
Query: 158 VSEYSKSSRKAFLERWDNPSKSRGSPDQFIRXXXXXXXXXXXXXXXXEKDTGKVFAMKMLDKEKVVKLKQVEHTVNEKKILDAVDFPFLITLNYHFKDNSYLYIVMDYIGGGEMFTHIRKYGRFSENFARFYGAQVVLAFEYLHNLDIIYRDLKPENVLIGTNGYIRITDFGFAKRIQGRTWTLCGTPEYLAPEIILCKGYNKSVDWWALGIFIYEMTSGYPPFVADQPIQIYEKIVLGKMKFNQYFSVELKDILRYLLQTDLTRRYGNLRNGVNDIKNHKWFNGKCDWIELFHQQVPPPILPKMKSIDDTSNFDKYEEEQFPISNIEKHPAEFLDF 1168
+ + + +++ F+E+WD PS++ F R++TLGTG+FG V LV+ K T + A+K+LDK+KVVKLKQVEHT+NEK+IL A+ F FL+ L+YHFKDNS LY+V++++ GGEMF+H+R+ GRFSE +RFY AQ+VLAFEYLH LD+IYRDLKPEN+LI + GYI++TDFGFAKR++GRTWTLCGTPEYLAPEIIL KGYNK+VDWWALG+ IYEM +GYPPF ADQPIQIYEKIV GK++F +FS +LKD+LR LLQ DLT+RYGNL+N V DIK HKWF CDWI +F +++ P +P +K D+SNFD YEEE I+N EK EF DF
Sbjct: 247 MKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWF-LNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 582 The following BLAST results are available for this feature:
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit alpha vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30004363 ID=SMED30004363|Name=cAMP-dependent protein kinase catalytic subunit alpha|organism=Schmidtea mediterranea sexual|type=transcript|length=1386bpback to top protein sequence of SMED30004363-orf-1 >SMED30004363-orf-1 ID=SMED30004363-orf-1|Name=SMED30004363-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=353bp MGSSHSSKKTDSAEEVSEYSKSSRKAFLERWDNPSKSRGSPDQFIRVKTLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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