Protocadherin-11 X-linked
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30004358 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of Protocadherin-11 X-linked vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 228.024 bits (580), Expect = 2.926e-60 Identity = 199/699 (28.47%), Postives = 315/699 (45.06%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNI---RIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIR--FDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNL--DREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM-KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTN 2499
F + + I EN IG+ +P+P+A D+D+ GV +Y E Q Q+ QEE P L ++ N+DRE + S+ + D G+ + S + V V D NDNAP++ + +Y+ + E G ++++ AND D N + Y E +V ++ ++ N +T + G ++R ++ R + A D N + V + ++D ND+ P I I + + E+ ++ + VQV D D+G N C + L+ D+ Y ++T T D EK+ YT+EI VD GNP +SS + ++DVNDNAP F + ENN G + ++ A D DS +N +VYS+ + F IS GEIQ K DRE+ +SYE V A D G P L + V V + D ND P F Y F + E+ + + D D G+N V +L E N V +G ++ +L DRE+ S+ ++A D G P S + I VLD NDNAP PSN + + ++ + +G+T+ V +D D G+N + +S+ N P+ + G A T+ KE RL++K SD G+ P+ A +++ +L N
Sbjct: 168 FASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY----------ELQAGPEAQELFGLQVAE---DQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSD--QGANAEIEYTFHQAPE---VVRRLLRLDRNTGLIT---VQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTT--TPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENM---PALSPVGMVTVIDGDKGENAQV----------------QLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL-LTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGN-----PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLAN 818 HSP 2 Score: 107.457 bits (267), Expect = 7.723e-23 Identity = 82/305 (26.89%), Postives = 138/305 (45.25%), Query Frame = 1
Query: 1429 VDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISIYGEIQSKIK-------FDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFL-----FPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTIT 2292
V G+P + Q I + D+NDN P F + + + EN IGS A D D+ NG Y + + + F + + + + K DRE+ DSY+ + +D G P S +++V + D ND P FE+ Y ++E+ S + Q+KA D D G N ++Y + +R L+++ + G I+V G +DRE++S+++ V A D G S +++ V D+NDNAP ++ N+S + + V+ D D+G N +T
Sbjct: 144 VQNGSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSEN---SPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV-----------VRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVT 431
BLAST of Protocadherin-11 X-linked vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 226.868 bits (577), Expect = 3.454e-60 Identity = 199/699 (28.47%), Postives = 315/699 (45.06%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNI---RIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIR--FDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNL--DREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM-KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTN 2499
F + + I EN IG+ +P+P+A D+D+ GV +Y E Q Q+ QEE P L ++ N+DRE + S+ + D G+ + S + V V D NDNAP++ + +Y+ + E G ++++ AND D N + Y E +V ++ ++ N +T + G ++R ++ R + A D N + V + ++D ND+ P I I + + E+ ++ + VQV D D+G N C + L+ D+ Y ++T T D EK+ YT+EI VD GNP +SS + ++DVNDNAP F + ENN G + ++ A D DS +N +VYS+ + F IS GEIQ K DRE+ +SYE V A D G P L + V V + D ND P F Y F + E+ + + D D G+N V +L E N V +G ++ +L DRE+ S+ ++A D G P S + I VLD NDNAP PSN + + ++ + +G+T+ V +D D G+N + +S+ N P+ + G A T+ KE RL++K SD G+ P+ A +++ +L N
Sbjct: 168 FASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY----------ELQAGPEAQELFGLQVAE---DQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSD--QGANAEIEYTFHQAPE---VVRRLLRLDRNTGLIT---VQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTT--TPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENM---PALSPVGMVTVIDGDKGENAQV----------------QLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL-LTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGN-----PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLAN 818 HSP 2 Score: 106.686 bits (265), Expect = 1.294e-22 Identity = 88/337 (26.11%), Postives = 148/337 (43.92%), Query Frame = 1
Query: 1375 DTSFDREKIS-----------VYTVEIKCVD---QGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISIYGEIQSKIK-------FDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFL-----FPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTIT 2292
+TS DRE + + E+ D G+P + Q I + D+NDN P F + + + EN IGS A D D+ NG Y + + + F + + + + K DRE+ DSY+ + +D G P S +++V + D ND P FE+ Y ++E+ S + Q+KA D D G N ++Y + +R L+++ + G I+V G +DRE++S+++ V A D G S +++ V D+NDNAP ++ N+S + + V+ D D+G N +T
Sbjct: 112 ETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSEN---SPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV-----------VRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVT 431
BLAST of Protocadherin-11 X-linked vs. Ensembl Human
Match: PCDHGB6 (protocadherin gamma subfamily B, 6 [Source:HGNC Symbol;Acc:HGNC:8713]) HSP 1 Score: 202.216 bits (513), Expect = 5.947e-53 Identity = 196/708 (27.68%), Postives = 322/708 (45.48%), Query Frame = 1
Query: 184 VEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKL--YLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIY-------KIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAISIY-------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-------EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTI-------IIEVL-DLNDNAPVFLFPSNNMNF 2202
+ +S+ E G VVGN+ L + ++ + + +FS++ SGDL+VK+ +DRE IC+ + C ++L ++ + +++ I D+ND+ P F + + I E+ GT L A D D +K Y I N+ +F + + YP L + K +DREE S IL A D G+ ++ + + + V D NDN P +++D Y++++ E G +L++ A D+D+ N ++Y + K +F ++ + NN+ + + + A DG G + V I I D ND+ P I I + ++LEN +++ + +D D G NG C NI D F IY K+ T D + DRE+ Y V I D+G P +SS + ++ + D+NDNAP F + HV ENNP G+++ QV A D D NGHI YSI+ S+ + A+S Y G + ++ FD E+ ++ + ARD+G P L+ ++ ++V + D ND P + FF + E + ++ A D D G N + Y ++ G+ LR G + L + + +LLV D G P LS T T+ + E+L DL+D PV P + F
Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSAEKLHFSVDAESGDLLVKNRIDREQICKERRR-CELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI----------------NSNPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRISLSENLPPGSPVLQVTATDQDE--GVNAEINYYFRSTAQSTK---HMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGGGLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPGMVVALFKTRDLDFGGNGEVRC-----------NIETDIPFKIYSSSNNYYKLVT--DGALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAE--PGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL-----FSLGLRT-------GEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADNLQEILPDLSDR-PVLSDPQAELQF 690 HSP 2 Score: 94.7449 bits (234), Expect = 5.828e-19 Identity = 88/297 (29.63%), Postives = 137/297 (46.13%), Query Frame = 1
Query: 1474 INIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI--------YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI 2340
+ I DVND+AP+F K + E+ G+ + A D D + N Y I NSN F++ + Y E+ + DRE+ S+ ++TA D G+P + + +++ ++D ND PVF +D + RI+ S + L Q+ ATD+D G N + Y S ++ G I + D E++ + V+A D G LST +IIE+LD NDN+P + S + + S G + KT+DLD G NG + N + PFKI
Sbjct: 121 VVIEDVNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI-NSNPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEY-RISLSENLPPGSPVL-QVTATDQDEGVNAEINYYF----------RSTAQSTKHMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPP---GMVVALFKTRDLDFGGNGE-----VRCNIETDIPFKI 394
BLAST of Protocadherin-11 X-linked vs. Ensembl Human
Match: PCDHGB6 (protocadherin gamma subfamily B, 6 [Source:HGNC Symbol;Acc:HGNC:8713]) HSP 1 Score: 202.601 bits (514), Expect = 1.072e-52 Identity = 196/708 (27.68%), Postives = 322/708 (45.48%), Query Frame = 1
Query: 184 VEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKL--YLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIY-------KIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAISIY-------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-------EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTI-------IIEVL-DLNDNAPVFLFPSNNMNF 2202
+ +S+ E G VVGN+ L + ++ + + +FS++ SGDL+VK+ +DRE IC+ + C ++L ++ + +++ I D+ND+ P F + + I E+ GT L A D D +K Y I N+ +F + + YP L + K +DREE S IL A D G+ ++ + + + V D NDN P +++D Y++++ E G +L++ A D+D+ N ++Y + K +F ++ + NN+ + + + A DG G + V I I D ND+ P I I + ++LEN +++ + +D D G NG C NI D F IY K+ T D + DRE+ Y V I D+G P +SS + ++ + D+NDNAP F + HV ENNP G+++ QV A D D NGHI YSI+ S+ + A+S Y G + ++ FD E+ ++ + ARD+G P L+ ++ ++V + D ND P + FF + E + ++ A D D G N + Y ++ G+ LR G + L + + +LLV D G P LS T T+ + E+L DL+D PV P + F
Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSAEKLHFSVDAESGDLLVKNRIDREQICKERRR-CELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI----------------NSNPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRISLSENLPPGSPVLQVTATDQDE--GVNAEINYYFRSTAQSTK---HMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGGGLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPGMVVALFKTRDLDFGGNGEVRC-----------NIETDIPFKIYSSSNNYYKLVT--DGALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAE--PGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL-----FSLGLRT-------GEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADNLQEILPDLSDR-PVLSDPQAELQF 690 HSP 2 Score: 94.7449 bits (234), Expect = 5.867e-19 Identity = 88/295 (29.83%), Postives = 136/295 (46.10%), Query Frame = 1
Query: 1480 IIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI--------YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI 2340
I DVND+AP+F K + E+ G+ + A D D + N Y I NSN F++ + Y E+ + DRE+ S+ ++TA D G+P + + +++ ++D ND PVF +D + RI+ S + L Q+ ATD+D G N + Y S ++ G I + D E++ + V+A D G LST +IIE+LD NDN+P + S + + S G + KT+DLD G NG + N + PFKI
Sbjct: 123 IEDVNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI-NSNPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEY-RISLSENLPPGSPVL-QVTATDQDEGVNAEINYYF----------RSTAQSTKHMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPP---GMVVALFKTRDLDFGGNGE-----VRCNIETDIPFKI 394
BLAST of Protocadherin-11 X-linked vs. Ensembl Human
Match: PCDHGB5 (protocadherin gamma subfamily B, 5 [Source:HGNC Symbol;Acc:HGNC:8712]) HSP 1 Score: 198.749 bits (504), Expect = 6.259e-52 Identity = 194/707 (27.44%), Postives = 320/707 (45.26%), Query Frame = 1
Query: 181 NVEFSVDENCRIGHVVGNVYSKLN----QLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQ--ENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQE-EIYPSLEIIKNIDREEFVSFVFILIATDFGNQ--TGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAISIY-------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-------EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTI-------IIEVL-DLNDNAPVFLFPSNNMNF 2202
+ + + E G VVGN+ + L +LP ++ + + YF+++ SG+L+V S LDRE IC K C+++ + + + + N + TQ +Q E+ GT + L VA+D D ++ Y + ++ +F K KQ+ YP L + K +DRE+ +L A D G+ +G+ + + VTD NDN P + +D Y+V+++E G +L++ A D+D+ N ++Y RT QIF +N +T + + + DG G + + +V+I I+D ND+ P ++ + +LEN ++ +++ D+D G NG C L G++ K I N YK+ T D + DRE+ Y V I D+G P +SS ++I DVNDNAP F + V ENNP G+++ QV A DLD NG + YSI+ S+ + A++ Y G + ++ FD E+ ++E + ARD G P L+ ++ ++V + D ND P + F + E + ++ A D D G N + Y ++ G+ LR G + L + + +LLV D G P LS T T+ + EVL D+ D PV P + F
Sbjct: 32 QIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRK----LRVSSEKPYFTVSAESGELLVSSRLDREEIC-GKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKL-------------SLNPSFSLII----KEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSATDQDE--GINSEITYSFY-RT------GQIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGGGLVAQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVNCQLQ--GEVPFKIISSSKNS--YKLVT--DGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAE--PGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL-----FSLGLRT-------GEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDR-PVPSDPQAELQF 686 HSP 2 Score: 160.229 bits (404), Expect = 1.586e-39 Identity = 136/451 (30.16%), Postives = 211/451 (46.78%), Query Frame = 1
Query: 1120 MNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQV-KDEDKGRNGM--FECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGE-SIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI------QPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLG 2439
+N V++ IED NDH P + N F + Q ++V +D D G N + ++ SLN S L +K + + +E + DRE+ S + + + +D G+P +S + I + D NDN P F + + EN P G+TV QV A D D N I YS + F++ S GEI ++ K D E+T Y VV RD G L V++ IQD ND +P + F + E E ++ + IK D+D G+NG V +L P I +SK N K+ DG LDRE+ + + A D G P LS++ ++I+ + D+NDNAPVF V+V G +I V DLD G+NG +++S++ S+ P + + ++ A ++ R+ L ++A D G
Sbjct: 114 LNFYHVNVEIEDINDHTPKFT-QNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEK----TLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGG--GLVAQCTVEINIQDENDNSP---EVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSK------NSYKLVTDG------TLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVF---HQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLE---PLALASYVSMSAQSGVVFAQRAFDYEQLRTF--ELTLQARDQG 534 HSP 3 Score: 159.844 bits (403), Expect = 2.508e-39 Identity = 154/577 (26.69%), Postives = 262/577 (45.41%), Query Frame = 1
Query: 844 PEWTKDNYKVNIQECQSEGD--ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKL-HLTNNRISGLINRNNIRIYITATDGNGR--MNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHI--------VYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITE--SYGESIKNERLEQIKATDKDLGQNGTVKYRLI--DVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPS----NNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNP 2508
P++T++++++ I E G ILE +A D D N L Y+LS I+ + +G+K L + ++ R+ +TA DG T + I + D ND+PPV + + EN + V D+D+G N S +G++ F N +I T D E+ Y++ ++ D G + + INI D NDN+P + ++EN G+ + ++ D DS NG + + I++S+ N ++ + DRE+T Y +TA D G+P L+ S+ V + I+D+ND PVF + Y + E G SI Q+ A+D DLG NG V Y ++ D++P+ + + A+ G + D E++ + +L +QA D G P+LS ++ + V D NDNAP L+P+ + F V E G + V D D G N +++ ++ +++ F ++ GE+ A + + R RL++ D GQ P + ATL++ + SL + P
Sbjct: 131 PKFTQNSFELQISESAQPGTRFILE-VAEDAD--IGLNSLQKYKLSLNPSFSLIIKE--KQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQI------FSLNSKSGEITT--QKKLDFEETKEYSMVVEGRDGG--GLVAQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSY-----KLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIA-----QVCASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQ---------SGVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLR-TGEVRTARALGDRDAAR---QRLLVAVRDGGQPPLSATATLHLVFADSLQEVLP 669 HSP 4 Score: 87.8113 bits (216), Expect = 7.121e-17 Identity = 91/287 (31.71%), Postives = 133/287 (46.34%), Query Frame = 1
Query: 1504 PRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--FAISI-YGEIQSKIKFDREK------TDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYF-FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGA----ISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEI--GKTICTVKTKDLDQGINGTITHSLINSNK 2316
P +I+ + + E P GS VG + A DL S + S++ F +S GE+ + DRE+ + EF A E LN V V+I+DIND TP F ++ F +I+ES + R A D D+G N KY+L L +IK DG+ +++ LDRE+ S +L++ A D G+P LS TT + I+V D NDN PVF N + VS+ + G T+ V D D+GIN IT+S + +
Sbjct: 27 PALCEQIR-YRIPEEMPKGSVVGNL-ATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVA----ENPLN-FYHVNVEIEDINDHTPKFTQNSFELQISES---AQPGTRFILEVAEDADIGLNSLQKYKL------------SLNPSFSLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVF-----NRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQ 286
BLAST of Protocadherin-11 X-linked vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 160.614 bits (405), Expect = 2.078e-39 Identity = 168/560 (30.00%), Postives = 258/560 (46.07%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNN---------IRIYITATDGNGRMNETS--VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKI----SVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAI-SVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNF-VNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQP-EGEIIIAHTM--KEFSNFRSLPDRLIIKASDLGQNPKN 2454
+P + KD+Y I+E G +L + A D D + +NG + Y L + NG L L N SG+I IR+ + A+D E++ V+I + D ND+ PV + + +LEN ++ TV+ DED G NG S+ S + I + RE+I S T I+ D PA+SS +IN+ID+ND+AP + KM + EN IG VG+V A+D DS NG I YS+ S D G I++ DRE T Y VTARD G P LN S + V ++DIND P F+ K+Y I+E E + ++ +KA D D Q + YR+ + E+ +++ + GAI SV G L R++ +++ + A D G L + + + D+N +AP F N+ F V + IG + T+K +D D+G N I +S+ +S F+I P G+I ++ + ++ + F +I+ ASD P N
Sbjct: 267 SPIFEKDSYFGEIREDAPIGTTVLSVFARDLD--SGENGEIEYSLGEG-------------NGKNL-LAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTL-----------RERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISE---EMPRGSQIITLKAVDNDEDQK--ITYRI-----------EEADREVFSILDIGDQGAILSVSGELKRQD-HKVRVEISATDQG--GLQGRCVVNVFIDDVN-SAPYF----NDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQF-----FRIDPSSGDISVSSDLDREDRATF-----SVIVTASDHASPPLN 765 HSP 2 Score: 128.257 bits (321), Expect = 2.081e-29 Identity = 156/608 (25.66%), Postives = 269/608 (44.24%), Query Frame = 1
Query: 487 TTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQG--IDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQT--GSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNN--IRIYITATDGNGRMNETSVDIAIEDCN------DHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLI---DVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPV---FLFPSNNMNFVNVSVEWEIG 2232
QK+I ++EN+ IG A D+DS G+ Y + + ID+++ + ++ K +DRE + + A D G + S T+ V++ D+NDNAP + K Y V I E G I+ L A D D+ + ++Y++ + DR++ S I I L+ +SG + R + +R+ I+ATD G V++ I+D N DHP + K+ E+ + T++ +D D+G N S++ S + R D + + + DRE + ++V + D +P +++ + + + D+NDN+P+F + + E+ P+G++ QV A+D D NG + Y + S+ + +I ++ G ++ K DRE+ + ARD G P L+ + + + + D+ND P FE+ Y I E+ S + I A D D G N + +R+ D K I +++ +R L + FD + SS QL S+T + I V D+NDN P F+ N F NV + +IG
Sbjct: 481 AAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFIIDEDSGL-------------------------IKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE----DQKITYRIEE--ADREVFS-ILDIGDQGAILS---VSGELKRQDHKVRVEISATDQGGLQGRCVVNVFIDDVNSAPYFNDHPFSV-------KIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSS-----QFFRIDPSSGDISVSS----DLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAEN---SPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSGQL------------SSTVPVRIHVSDVNDNKPALKDFVILMN--RFDNVQMARQIG 1020 HSP 3 Score: 125.561 bits (314), Expect = 1.461e-28 Identity = 133/477 (27.88%), Postives = 216/477 (45.28%), Query Frame = 1
Query: 931 DDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATD-GNGRMN-ETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNE-----RLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
D+ + NG++ Y + + +ED F I+ + + + L++R Y +TA D G +N T++ + ++D ND+ P + E + + T++ D D+ + + D ++ +I D AI + R+ V VEI DQG + ++ I DVN +AP F + + E++PIG V ++A D D +N IVYSI +S+ F I G+I DRE ++ +VTA D+ P LN S ++V + DIND +P F + SY +I + Q+ A D D+G NG V Y L + +S +L L + S G + V LDRE+ + I L + A D G PSLS + I + + D+NDNAP F S ++ S +G T+ T+ +D D+G N I+ + + F
Sbjct: 505 DEDSGPNGIIKYSM-EGSED-------FIIDEDSGLIKTTK---LLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDI--GDQGAILSVSG----ELKRQDHKV-RVEISATDQG--GLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI-DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQF-------TSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNE-------SSSSPSIQLFRLDRTS--GTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENS---PVGSTVGTIVARDADEGDNADISFRIFGGADAKLF 940 HSP 4 Score: 113.62 bits (283), Expect = 5.349e-25 Identity = 105/352 (29.83%), Postives = 169/352 (48.01%), Query Frame = 1
Query: 1498 NAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFV-NVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSIGKK 2526
NA F + + + E+ PI + + V+A S + YS++ D+ + +++ GEI+ DRE D + VTA + +P ++ S V V + D+ D +P+FEKD YF I E ++ + + A D D G+NG ++Y L + GN K NL+ + + G I LDRE +S I+L V A D G P +T + I V+D+NDNAPVF S N+ + N++ I I TVK D D G NG + +S+ +S+ GE+ T++E + ++ P +I+A D Q ++ L I I + + PT I +
Sbjct: 161 NAVHFQQEKYVKELPEDTPIETIIASVKASHASSQP---LYYSMVAPQDSRSQNLFTLDTMSGEIRLAKSMDREVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIRE---DAPIGTTVLSVFARDLDSGENGEIEYSLGE-------GNGK------NLLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENIT----IPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYS-TGEV----TLRERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVI-DINDHAPTLIAAQ 483 HSP 5 Score: 109.383 bits (272), Expect = 1.288e-23 Identity = 164/650 (25.23%), Postives = 280/650 (43.08%), Query Frame = 1
Query: 193 SVDENCRIGHVVGNVYS-KLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQEN-QVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATD-GNGRMN-ETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGK-LNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--FAISIYGE------IQSKIKFDRE-KTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLID---VKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQ 2088
+++EN IG VG VY+ + PN M+ +E F ++ SG + LDRET + + + + + I + + DINDN P F + + I E +P G+ A D D + K Y R + D+E + IG+ + +Q+ R E + ATD G G C V V + DVN AP + + V I E G ++ L A D D N + Y + SQ F I+ + ++ + +R + +TA+D + +N T +++ ++D ND+ P + ++ + E+ V D D G NG+ + LN+S +++ R D ++ + DRE+ +V + I D+G P++S+ + ++ + DVNDNAP F ++ EN+P+GSTVG + A D D +N I + I D F I E I ++ +FD E K + + F + A QL+ ++ V++ + D+ND P + F + + ++ I A D D QN T++Y L + ++ G +K E + + VSF +S N + I +LV+
Sbjct: 487 TLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED---FIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ---KITY--RIEEADREVFSILDIGDQGAILSVSGELKRQDHKV----------RVE-------ISATDQGGLQGRCVVNVFIDDVNS-APYFNDHPFSVKIPEHSPIGYPVITLKAEDHD--RGDNARIVYSIDS--------SQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSS----KLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSG---QLSSTVPVRIHVSDVNDNKPALKD--FVILMNRFDNVQMARQIGFIPAFDPD--QNATLEYFLEENDLIEAEKYTGKILVKQEWKRNMDVSFKTCVSDGANTECSTCRFIHVLVE 1089
BLAST of Protocadherin-11 X-linked vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 151.754 bits (382), Expect = 1.222e-36 Identity = 140/450 (31.11%), Postives = 214/450 (47.56%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKI----SVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAI-SVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNF-VNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQP-EGEIIIAHTM--KEFSNFRSLPDRLIIKASDLGQNPKN 2454
V+I + D ND+ PV + + +LEN ++ TV+ DED G NG S+ S + I + RE+I S T I+ D PA+SS +IN+ID+ND+AP + KM + EN IG VG+V A+D DS NG I YS+ S D G I++ DRE T Y VTARD G P LN S + V ++DIND P F+ K+Y I+E E + ++ +KA D D Q + YR+ + E+ +++ + GAI SV G L R++ +++ + A D G L + + + D+N +AP F N+ F V + IG + T+K +D D+G N I +S+ +S F+I P G+I ++ + ++ + F +I+ ASD P N
Sbjct: 2 VEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTL-----------RERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISE---EMPRGSQIITLKAVDNDEDQK--ITYRI-----------EEADREVFSILDIGDQGAILSVSGELKRQD-HKVRVEISATDQG--GLQGRCVVNVFIDDVN-SAPYF----NDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQF-----FRIDPSSGDISVSSDLDREDRATF-----SVIVTASDHASPPLN 406 HSP 2 Score: 127.872 bits (320), Expect = 2.337e-29 Identity = 156/608 (25.66%), Postives = 269/608 (44.24%), Query Frame = 1
Query: 487 TTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQG--IDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQT--GSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNN--IRIYITATDGNGRMNETSVDIAIEDCN------DHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLI---DVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPV---FLFPSNNMNFVNVSVEWEIG 2232
QK+I ++EN+ IG A D+DS G+ Y + + ID+++ + ++ K +DRE + + A D G + S T+ V++ D+NDNAP + K Y V I E G I+ L A D D+ + ++Y++ + DR++ S I I L+ +SG + R + +R+ I+ATD G V++ I+D N DHP + K+ E+ + T++ +D D+G N S++ S + R D + + + DRE + ++V + D +P +++ + + + D+NDN+P+F + + E+ P+G++ QV A+D D NG + Y + S+ + +I ++ G ++ K DRE+ + ARD G P L+ + + + + D+ND P FE+ Y I E+ S + I A D D G N + +R+ D K I +++ +R L + FD + SS QL S+T + I V D+NDN P F+ N F NV + +IG
Sbjct: 122 AAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFIIDEDSGL-------------------------IKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE----DQKITYRIEE--ADREVFS-ILDIGDQGAILS---VSGELKRQDHKVRVEISATDQGGLQGRCVVNVFIDDVNSAPYFNDHPFSV-------KIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSS-----QFFRIDPSSGDISVSS----DLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAEN---SPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSGQL------------SSTVPVRIHVSDVNDNKPALKDFVILMN--RFDNVQMARQIG 661 HSP 3 Score: 125.176 bits (313), Expect = 1.788e-28 Identity = 133/477 (27.88%), Postives = 216/477 (45.28%), Query Frame = 1
Query: 931 DDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATD-GNGRMN-ETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNE-----RLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
D+ + NG++ Y + + +ED F I+ + + + L++R Y +TA D G +N T++ + ++D ND+ P + E + + T++ D D+ + + D ++ +I D AI + R+ V VEI DQG + ++ I DVN +AP F + + E++PIG V ++A D D +N IVYSI +S+ F I G+I DRE ++ +VTA D+ P LN S ++V + DIND +P F + SY +I + Q+ A D D+G NG V Y L + +S +L L + S G + V LDRE+ + I L + A D G PSLS + I + + D+NDNAP F S ++ S +G T+ T+ +D D+G N I+ + + F
Sbjct: 146 DEDSGPNGIIKYSM-EGSED-------FIIDEDSGLIKTTK---LLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDI--GDQGAILSVSG----ELKRQDHKV-RVEISATDQG--GLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI-DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQF-------TSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNE-------SSSSPSIQLFRLDRTS--GTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENS---PVGSTVGTIVARDADEGDNADISFRIFGGADAKLF 581 HSP 4 Score: 108.612 bits (270), Expect = 1.788e-23 Identity = 166/650 (25.54%), Postives = 281/650 (43.23%), Query Frame = 1
Query: 193 SVDENCRIGHVVGNVYS-KLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQEN-QVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATD-GNGRMN-ETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKL-NLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--FAISIYGE------IQSKIKFDRE-KTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLID---VKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQ 2088
+++EN IG VG VY+ + PN M+ +E F ++ SG + LDRET + + + + + I + + DINDN P F + + I E +P G+ A D D + K Y R + D+E + IG+ + +Q+ R E + ATD G G C V V + DVN AP + + V I E G ++ L A D D N + Y + SQ F I+ + ++ + +R + +TA+D + +N T +++ ++D ND+ P + ++ + E+ V D D G NG+ + LN+S +++ R D ++ + DRE+ +V + I D+G P++S+ + ++ + DVNDNAP F ++ EN+P+GSTVG + A D D +N I + I D F I E I ++ +FD E K + + F + A QL+ ++ V++ + D+ND P KD F + + ++ I A D D QN T++Y L + ++ G +K E + + VSF +S N + I +LV+
Sbjct: 128 TLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED---FIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ---KITY--RIEEADREVFSILDIGDQGAILSVSGELKRQDHKV----------RVE-------ISATDQGGLQGRCVVNVFIDDVNS-APYFNDHPFSVKIPEHSPIGYPVITLKAEDHD--RGDNARIVYSIDS--------SQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSS----KLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSG---QLSSTVPVRIHVSDVNDNKPAL-KD-FVILMNRFDNVQMARQIGFIPAFDPD--QNATLEYFLEENDLIEAEKYTGKILVKQEWKRNMDVSFKTCVSDGANTECSTCRFIHVLVE 730 HSP 5 Score: 65.4698 bits (158), Expect = 2.853e-10 Identity = 54/186 (29.03%), Postives = 86/186 (46.24%), Query Frame = 1
Query: 1771 VVKVKIQDINDCTPVFEKDYFFRITESYGESIKN-----ERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNF-VNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINS 2310
+V++ + D+ND PVF D SY +I + +KATD+D G NG V Y + IG L G +++ +D + S I +++A D P+LS+T + I V+D+ND+AP + + NV++ E+G+ V D D G NG I +S+ S
Sbjct: 1 MVEITVVDVNDNAPVFASD-------SYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIG------------GLTIDYSTGEVTLRERIDAKN-SPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGR----VYAIDEDSGPNGIIKYSMEGS 162
BLAST of Protocadherin-11 X-linked vs. Ensembl Celegans
Match: cdh-4 (Cadherin-4 [Source:UniProtKB/TrEMBL;Acc:A0A1C3NSI5]) HSP 1 Score: 129.413 bits (324), Expect = 8.436e-30 Identity = 170/710 (23.94%), Postives = 302/710 (42.54%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXX--XAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNG---RMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDN--APRFVNKIKMFHVVENNPIGSTVGQVRAM---DLDSSNNGHIVYSILNSND--NFAISIYGEIQSKIKFDREKTDSYEFVVTARDNG-----EPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYG--NLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSIGKKSHSSDNN 2547
F + +++ + E+ PIGT A D+D+ G Y I G E V T+ + + SK ++K ++ E + + A D G S T+ + + ++P++ + +Y + I E + G DI ++ AND D N NG + + L + E ++S KL + +R ++ + G R++ T++ I++ED ND+PP + + ++ E+ ++ + DED G+N + LN S K+ R D + I P+ D K + + I+ D G+P +S+ + ++D+ N A F + K V EN+ IG+ V + A D ++ Y I+ + +F+I G +++ DRE +Y V ARD+ +P+ D + V ++I D ND PV +K Y + E+ ++ ++E A D D + +++ P S + +L + G I+ G LDRE+ S +L V D G P L + +I+ VLD NDN+P F + SV + +C + D D+G N +T+++ + R F I G II + + ++ L ++A+D G + AT + L S G+K S N+
Sbjct: 608 FSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHE--VLTVDEQSGEITVASDLSK---------LMK--EKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGN--NGKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDR-----EDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLN-SEKVPF---RIDHHSGCIFIHA-PEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDGWPHFSIDQKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDP-----QSFFRIDLTS-------GYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTF-----TQAIHHYSVRSKFAGKLCRIFAVDADEGENARLTYNITEGDAR----FSIDNNGNIIASEAIHGDESY-----ALTVQATDHGTPGQQFAATRVV--------LTANSAGQKPRKSKNS 1258 HSP 2 Score: 107.071 bits (266), Expect = 5.560e-23 Identity = 197/777 (25.35%), Postives = 335/777 (43.11%), Query Frame = 1
Query: 190 FSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSY--FSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQ--DTHAXXXXXXXXXXXXX-XXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDR-EKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQ-VRAMDLDSSNNGHIVYSILNSNDN-FAIS-IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVN-VSVEWEIGKTICTVKTKDLDQGINGTITHSL-INSNKREN---FPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYI 2475
FSV E+ +G+V+G V ++ + + + E DS+ FS+ R++G +IVKS LDRE K M + D HAI V ++ P F + I E+ +GT+ + A D+D G + + +NP E L + +DRE+ + I ATD G T++V+DVND+ P++ K+ + +++ S IL + +DD + N + + + E+ +F+I+ N L R + N+ ++ +TA DG + T V I ++ D AN+ + EN K+ T V + G N F+ S ND G + + N R I K++ +++ +++ + + I Q N + + ++ I ++NDN P+ + K+ + EN P Q + + + ++ I + +++ F I I G + D E + V A D + D + V + D ND P FEK Y ++ ES ESI E L +A+ D QN T++Y L KP + L A+ G +++ LD E +S+++L V A D G P L T + I V+D NDNAP F +V V + G+ + TVK D+D G +++ L I S + PF I G+++I+ ++ ++ + L + A D G+ P + A L I
Sbjct: 2615 FSVMEDADVGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRER-----KNQWKMTIRADAAGGVHAITTVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVE----------------------ENPYFDLNENSGWLTVASQLDREKIDHYKLIARATDEGGFNTDLPFTIVVSDVNDSPPQFEKEEFNIDLH-LPSTSPILHF--SIKDDDLSPNNVSQFFIPKGNEE-----GVFWIDSNN-DLLLKRPEIVENKMQYQLKVTAFDGVFETS-TKVKINLKSSKDSDIRCPEANKTVILAENSKKG---TVVLGESSLLGPNVTFKLSDND-GNVFVVNFRN----GIVKVKESDQIDYEKNQQLEFHRLTI----QDNSEVCK-ELITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDADFDEIKFRMVDDFGGLFQIDDINGVVTVVKPLDSEILGFFNLTVVASDG---EFEDKATILVTVIDQNDNAPTFEKSTYSMKVMES--ESIGYE-LAHFRASGGD--QNETIEYYL---KPSDVTSFVNLNAQT---------GILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKF----EKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSI-DYEKIKKY--NLKVIAKDGGRPPLRSEALLEI 3314 HSP 3 Score: 97.8265 bits (242), Expect = 3.643e-20 Identity = 98/383 (25.59%), Postives = 166/383 (43.34%), Query Frame = 1
Query: 1150 EDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTS-FDREKISVYTVEIK--CVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI----SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTP-VFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVK-PIGIPGNSKLKAELRNLIKVSFDGAISVYG---NLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKD 2262
E N H PV S +V E+ ++ +Q DED G NG ++D + + + D+ +I D S +EK+ V V++K +D G P SS++ + I DVN+++P+F + EN G + +V A D D NNG I +S+ N+ + ++ + G ++ DRE D + F + A D G P + + ++D+ND P + RI E + + A D+D+GQN +K+ L K P I +S G I ++ LD + L ++ D G P LST+ + +E++D+ N F + +V EIG + ++ K+
Sbjct: 599 ESENKHSPVFSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLTVDEQSG--EITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPH---GAFVSCMAAFDEDIGQNSKLKFLLNSEKVPFRIDHHS---------------GCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEF-DDVAKEASVYENSEIGTEVIMIEAKE 960 HSP 4 Score: 88.1965 bits (217), Expect = 3.944e-17 Identity = 82/331 (24.77%), Postives = 148/331 (44.71%), Query Frame = 1
Query: 865 YKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNE--TSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYP-----DTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYF 1833
Y +I E EGD + +++ DD +N + Y L D +E SQ F ++ + +T + + + I ATD + T+V++ I + P S ++ V+E+ ++ GR E +++ + D+F + +E +S DRE+ + + + I+ G + ++ +++I DVNDNAP F + F + E+ +G++V AMD D S +G I +S++ N F ++ G + + DREK D Y+ + A D G N + + + D+ND P FEK+ F
Sbjct: 2510 YSTSISESAKEGDTVMMVSATDDD---ENDTIEYSLLDGSE-----SQFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDADVGNVI----------GRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTIRADAAG--GVHAITTVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEENPYFDLNENSGWLTVASQLDREKIDHYKLIARATDEG--GFNTDLPFTIVVSDVNDSPPQFEKEEF 2818 HSP 5 Score: 82.4185 bits (202), Expect = 2.043e-15 Identity = 92/341 (26.98%), Postives = 149/341 (43.70%), Query Frame = 1
Query: 1474 INIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNL-IKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWE-IGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIR 2478
+ +ID NDNAP F V+E+ IG + RA D N I Y + S+ +++ G + D E + + V A+D+G P L V++ + D ND P FEK+ Y ++ E+ S E++ +KA D D G V Y L V S+ + L ++ +G + + ++D E+I L V A D G P L + + I V D ND+AP F ++ N + E E IG + DLD NG I + ++ FK+ + E++ A ++ + L L + A D+ + T++IR
Sbjct: 3101 VTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGD--QNETIEYYLKPSDVTSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKEN---SKSGEKVLTVKALDVDSEHFGAVSYELEIV--------SETTTDTPVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTF----DDCNMTALVQEGEAIGHRLLKFSVSDLDGPKNGAPFTVEIQGDGAKS--FKVNEKLELLTAKKLEYRKKDKYL---LTVIAKDVKGKTTDCPLTIFIR 3419 HSP 6 Score: 82.0333 bits (201), Expect = 2.318e-15 Identity = 71/288 (24.65%), Postives = 127/288 (44.10%), Query Frame = 1
Query: 1087 IYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--------FAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGT 1926
+ + A+DG ++ ++ + + D ND+ P + KV+E++ L + D+ N E L S + N+ D E +S + + D G P + + + I+++D NDNAP+F + + V EN+ G V V+A+D+DS + G + Y + ++ FAI+ G++ D EK Y V A+D G P L ++++ ++D ND P F+ + + GE+I RL + +D D +NG
Sbjct: 3084 LTVVASDGEFE-DKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGDQ--NETIEYYLKPSDVTSFVNLNAQTGILTLA------KPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQE-GEAI-GHRLLKFSVSDLDGPKNGA 3360 HSP 7 Score: 70.0922 bits (170), Expect = 1.010e-11 Identity = 75/300 (25.00%), Postives = 131/300 (43.67%), Query Frame = 1
Query: 1438 GNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY---GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQN-GTVKYRLIDVKPIG---IPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSN 2313
G A S++ ++++ID+ND P FV + E+ G TV V A D D N I YS+L+ +++ S++ G I K + + + + A D+ P + + V+V I + P F Y F + E D D+G G V+ ++ I +PG+ + + L ++ S G I V +LDRE + ++ ++A D + TT+ +++ D+NDNAP F + +S + +G ++ D D +G I SL+ N
Sbjct: 2484 GRRAFSTL---TLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDD--ENDTIEYSLLDGSESQFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVME-----------------DADVGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERS-TGKIIVKSSLDRERKNQWKMTIRA--DAAGGVHAITTVTVDIGDVNDNAPAF---HGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEEN 2755 HSP 8 Score: 57.3806 bits (137), Expect = 9.113e-8 Identity = 87/366 (23.77%), Postives = 154/366 (42.08%), Query Frame = 1
Query: 1141 IAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTV-EIKCVDQGNPAMSSMQKFSINIIDVNDNAP---RFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYF---FRITESYGESIKNERLEQ--IKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLST--TTTIIIEVLDLNDNAPVFLFPSNNMN 2199
+ I D ND+ P F V E+ +L TV D+D+G NG+ S+ + +L I E D E V ++ I+ +D A S + S++I + N+ AP +F K+ + ++ G+ V + L++ ++G + Y + + F + ++ G + + K ++ E Q + + V+ KI N +P+F + + R G S+ ++ L + A D+D G NG V YR++ K + V + GAI + D E++ VQAFD G P + + I++ V+D ND P FPSN+++
Sbjct: 1455 VNINDENDNSPYFVGHTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSG------EVRLAKPLDPELQHVESILRIRAIDSA--ANSLKDEMSLHIRNSNE-APETAKFDRKVYQTTLYDSTRPGTPV-----LVLNALHHGTVSYKLEPNCTFFEVHTLSGAVHLATWLTKLKHRKSVECTAIVESTEGQQDIAKVI-AKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRMLSPKD-------------EQMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPP--RFPSNSLD 1790 HSP 9 Score: 56.9954 bits (136), Expect = 9.586e-8 Identity = 94/378 (24.87%), Postives = 169/378 (44.71%), Query Frame = 1
Query: 1444 PAMSSMQKFSINIIDVNDNAPRFVNKIKM-FHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN-------FAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMV---VKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDG---AISVYG---NLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVF-LFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSL--INSNKRENFPFKIQPEGEIIIAHTMKEF--SNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNP 2508
P + + + +I I + ++ RF++ K+ E PIG + ++ + + I YS+ S + FAI S G ++ K +R + Y F V A +G +N+ + V ++I D ND PVF + + G+ + L ++ ATD+D G+NG + Y+ P+ I N+ E+ L++V G +V+ L +S++ L+ + +G + III+ + N ++PVF FP V V+ + IG + ++ D D G NG I + + I + E Q GEI +A + + L +L + A D G K+++ T+ +R I + N +P
Sbjct: 360 PVIPTNETVTIQIERLAEHLIRFLDNEKLTLKTDEMAPIGRILYRMNVNVENPDDVSLIRYSLEYSKSDLPNATLPFAIGSKNGILRVSAKINRSER-VYNFKVIASLHG---INEKLAEKDVSIEILDSNDHAPVFSAKWMRQTPIVIGKP--GDVLVKVDATDQDEGENGKIVYKFTSELPLEINANT---GEI-TLVEVPKKGNSWPATVWAIDLGLPLSRMSALNLMF--YKNGTKIPAKPKPIIIQESE-NKHSPVFSSFP----EIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLTVDEQ-SGEITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLR-IKDVNNHSP 718 HSP 10 Score: 51.9878 bits (123), Expect = 3.965e-6 Identity = 63/252 (25.00%), Postives = 100/252 (39.68%), Query Frame = 1
Query: 1063 LINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTS-------FDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFV-VTARDNGEPQLNDSMVVKVK 1785
L+ R +R+ I+ TDG + ++V I + P S ++ V E + T++ E G + NL ++ DD KI P + D E ++ V Q N M S FS+NI D NDN+P FV V E++ + + V A D D NG + YSI++ N+ I GE++ D E + + A D+ L D M + ++
Sbjct: 1326 LLKRGELRLNISVTDGQA-WDHSTVIIQVSRQISQRPKFSASHYQTDVSERVAVGTQIYTLKASGESLGTKPLV---------FNLFSV--DDVAMEDKIRVEPSSGNVIVMEPLDYEAARRIRAVVQ-VQQAN--MKSFATFSVNINDENDNSPYFVGHTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSGEVRLAKPLDPELQHVESILRIRAIDSAANSLKDEMSLHIR 1562
BLAST of Protocadherin-11 X-linked vs. Ensembl Celegans
Match: cdh-1 (CaDHerin family [Source:UniProtKB/TrEMBL;Acc:Q5F4W0]) HSP 1 Score: 117.857 bits (294), Expect = 3.271e-26 Identity = 92/289 (31.83%), Postives = 133/289 (46.02%), Query Frame = 1
Query: 1075 NNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYR 1938
+ + + I AT +G N+T V I IED ND+PP S + + E+ K VQ D+DK +NG S+ S + +I D + + + D E Y + +K D G P SS I+++DVNDNAP F V+EN+P + VG+V A D DS NG IVY I N ++ F I G + +K DRE + + A D G P + + ++ + D+ND P I G + + I A D D G NG+V YR
Sbjct: 803 DTVLLNIQATLPSGESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGS--SIEIDQ----FTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLS--ITPIVVPAGSPLSTA-IGTIVAMDPDKGLNGSVLYR 1082 HSP 2 Score: 89.3521 bits (220), Expect = 1.322e-17 Identity = 96/318 (30.19%), Postives = 137/318 (43.08%), Query Frame = 1
Query: 1384 FDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI----LNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDG-----YPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINS 2310
DRE Y + I+ D G PA + SI IID NDNAP F V N IGS + V+A D D N I Y I SN NFAIS G I + T ++ +V A D+G P L+ S VV + + +P D + + + ++N L I A Q K RLI G+S L + + V + + G LDRE S L DG +P L T + D+NDNAP + + + +++S+ G + T+ KD D G NG I +S++++
Sbjct: 191 LDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFAISQSGVITTTASLLPAST--HDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPL--DIIWLVESNSAHLMENSTLGSIVARVSIAQQYRDTKLRLI--------GSSALCPQQTDQAHVYL---LLLCGILDRETASEHHLKFLLEKDGQIIIEHPQLLT-------IGDINDNAPQW-----HSSQIHISLNRTQGGS-RTLTAKDPDLGQNGWIRYSVLDT 480 HSP 3 Score: 83.5741 bits (205), Expect = 8.214e-16 Identity = 126/510 (24.71%), Postives = 214/510 (41.96%), Query Frame = 1
Query: 844 PEWTKDNYKVNIQECQSEGDIL-ELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLI---------NRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKI--ETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTAR-DNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIK-NERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFV-NVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNK 2316
P++ K ++V I E G L +++AN+ N+K + Y L ++ E HLT + +SG + + + + + AT+ N + + + I ++D ND+ P+ V E K + L V D D +G F G+++ + +F+I + E + R + + + + D G + + I +ID + P+F E+ G +G V AM + YSI + + + SI G+I D + D+ + A +GE N + VV + I+D ND P F + S E +K +E ++A+DKD +NG V+Y +I PG+S I++ F G +S LD E + +L V+A D G P S+ T+ I VLD+NDNAP F M + N + +GK + +D D NG I + + N ++
Sbjct: 538 PQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKR--IRYSLQNQDE----------------HLTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMD---SGTF-------GEVSYHILSESSSFSINPVTGEVFAQKPLARGR---FHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSVGAM-------SKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGES--NQTQVV-IFIEDHNDNPPQFSSSL---VEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSH----PGSS---------IEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVA----RDKDSLENGQIVYRITNGSE 986 HSP 4 Score: 82.4185 bits (202), Expect = 1.684e-15 Identity = 71/258 (27.52%), Postives = 120/258 (46.51%), Query Frame = 1
Query: 1474 INIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--FAIS---IYGEIQSKI----KFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIK-NERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAP----VFLFPSNNMNFV 2205
+ + D NDNAP F +++ + E +G++ D D + IL N N F ++ + ++Q+ + + DRE D YE ++ A+D G+P + ++I D ND PVF + R T S +I L ++ATD D+G+N + Y D+K P NS +S G I+ +L S+ ++V A D G PSLS++ + I VL ++P ++L SN+ + +
Sbjct: 110 VEVDDENDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRS---RYTASVSANISIGSHLITVQATDADIGENSRISY---DIKKTSAPSNSNF--------AISQSGVITTTASL--LPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLM 351 HSP 5 Score: 77.7962 bits (190), Expect = 4.605e-14 Identity = 80/368 (21.74%), Postives = 160/368 (43.48%), Query Frame = 1
Query: 1141 IAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKF--SINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARD-NGEPQLNDSMVVKVKIQDINDCTPVFEKDYF---FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNL-DREEISSIQLLVQAFDDGYPSLSTTTTIIIEV--LDLNDNAPVFLFPSNNMNFVNVS 2214
+ + D ND+ PV + + + ++ + + D+D G NG + LN+ + + + ++ + D D + + + ++ D G+PA +++ K S+ + + +AP FV + HV+E+ +G+ + ++RA + N ++YS+ I + GE+ K D E ++ D NG + + +K+ ++ +++ PVF K + I+ GES+ Q++A D+D G +G VKY + D + S +K E G I + L R ++ Q+ V A+ P+ + TT+ +E+ D+ + P L S + S
Sbjct: 2218 VIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNI--VTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKEHQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNGRSAV---VPLKIVVEPVDEFAPVFTKSSYTLQIPISTPAGESVG-----QMQAIDEDGGVHGVVKYSISDRQ-------STVKIE-------EHTGIIRLQKPLVSRRNLTIEQITVVAYSS--PTKQSKTTVYLEIGPFDVQPSLPKLLLHSKPVQIAVAS 2559 HSP 6 Score: 77.7962 bits (190), Expect = 4.804e-14 Identity = 103/428 (24.07%), Postives = 169/428 (39.49%), Query Frame = 1
Query: 1072 RNNIRIYITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPR----FVNKIKMFHVVENNPIGSTVGQVR-AMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGE-----PQLNDSMVVKVKIQDINDCTPVFEKDYF-FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNK 2316
R+ + I A DG ++ + I I D ND+ PV S + V N L TVQ D D G N + + + + NFAI + T+ S + V + D G+P++SS +I ++ ++P ++ + H++EN+ +GS V +V A + I S L +Y + I DRE + +G+ PQL + I DIND P + + + G S + A D DLGQNG ++Y ++D + + I + G I V +D S I+ V+A D G P+LST ++ ++LD P F + V + + IG + V + G + I +SL N ++
Sbjct: 196 RDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPS------NSNFAISQSGVI-TTTASLLPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENSTLGSIVARVSIAQQYRDTKLRLIGSSALCPQQTDQAHVYLLLLCGI-LDRETASEHHLKFLLEKDGQIIIEHPQL-------LTIGDINDNAPQWHSSQIHISLNRTQGGS------RTLTAKDPDLGQNGWIRYSVLDTELVSIDKET---------------GRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQF---EKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQDE 584 HSP 7 Score: 75.0998 bits (183), Expect = 3.672e-13 Identity = 101/435 (23.22%), Postives = 182/435 (41.84%), Query Frame = 1
Query: 1087 IYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFG-KVLENQKQKIILTTVQVKDEDKGRNGMFECSL--NDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDN------AP-RFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI--YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKAT--DKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE 2349
+ I TDG R + +V + + D ND+ P + + ++ E+ + +L + D D G+NG F L + SG L+L + + + ++ + + + ++++ VD G P + + I+ N N AP F+ + + + E P G + +++ + YSI+ N + A S+ G I++ ++ DRE + Y V +G+ Q+ V V++ ++ND P F R+ E N R+ AT KD+ ++Y L+ P + + F G I + LD E + L ++A D S T T + I V D+NDNAP F P + + G+ ++ DLD G +T+SL + + F++ PE
Sbjct: 1697 LIIILTDGGSRNDSCTVRVTVADQNDNKPQLDASTPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSLDL--VPETGDLVLRRLSS----------LQSWKIKLRVVDHGVPGLYVEKNLEIS----NRNPQTEAKAPLEFLKQTYLSTIDEGLPRGQFIAKLQP------ELAGLTYSIVEGNIDSAFSVDSEGVIRTNLELDREILERYSLKVIGTGSGQ-QIGTR--VDVRVNNLNDNVPSFPMSKPRRVPE-------NLRVGSYVATVGAKDVDNLAPLRYFLVSDSSGQTPTHFNID---------QFTGTIHLTAPLDFEVLPEHTLTIKATDG---SFDTFTNLTIFVSDINDNAPTFSKPLYQTTVSPAT--FSPGQPFAKIEAHDLDA--RGALTYSL---GQGSSSIFRVAPE 2080 HSP 8 Score: 72.0182 bits (175), Expect = 2.690e-12 Identity = 60/237 (25.32%), Postives = 114/237 (48.10%), Query Frame = 1
Query: 1240 TVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLI 1944
T+ KD D G+NG S+ D+ +++ + I+ P+T D S ++ D G+PA+S+ + +++D P+F + + E+ PIG+ + +V A + N+ I YS+ N +++ + ++ G + + FD EK SY+ V A N + + S+ + ++++D+ND P+F +Y + E E L + A+D D G G V Y ++
Sbjct: 459 TLTAKDPDLGQNGWIRYSVLDTELVSIDK----ETGRIF----VPNT-IDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQDEHLTVDTMSGTVCIQKTFDFEKQKSYQTTVIAT-NANSETSTSL-ISIRLKDVNDNWPIFYPNEYHLTVREG---PKPEEPLLVVSASDMDSGTFGEVSYHIL 681 HSP 9 Score: 68.9366 bits (167), Expect = 2.351e-11 Identity = 102/423 (24.11%), Postives = 174/423 (41.13%), Query Frame = 1
Query: 1063 LINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLK-NIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENN-PIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDC-TPVFEKDYF-FRITE--SYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSN 2313
++ R ++++ T G+G+ T VD+ + + ND+ P ++ + +V EN + + TV KD D + + SG+ NI D F T P D E + +T+ IK D + + +I + D+NDNAP F + V G ++ A DLD+ G + YS+ + + +K + Y VTA DNG P + S+ V V I + P FEK F F + E G I N E+ + YR+ D E + + G + V G +DRE+ ++ + V+ ++ S + VLD NDN PVF ++ ++++ G+ I + D D G NG +++ +++ N
Sbjct: 1892 ILERYSLKVIGT---GSGQQIGTRVDVRVNNLNDNVPSFPMS-KPRRVPENLRVGSYVATVGAKDVDNLAPLRYFLVSDSSGQTPTHFNI---DQFTGTIHLTAP---LDFEVLPEHTLTIKATDG---SFDTFTNLTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLDA--RGALTYSLGQGSSSIFRVAPESGALFMKVLPPAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSKIGLQIGNLSGEESRE----------FHYRIQD-------------PEASKIFSIDKFGRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVF---TSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGN 2273 HSP 10 Score: 67.781 bits (164), Expect = 5.197e-11 Identity = 90/366 (24.59%), Postives = 146/366 (39.89%), Query Frame = 1
Query: 1504 PRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNF--AISIYGEIQSKIKFDREKTDSYEFV-VTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVS-------FDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSI-----GKKSHSSDNNNFG 2556
P F + F V E+ IG+ +G + +S+ + V F GEI + D EK ++ V V ++GE ++ + V++ D ND P F + + + L + TD D G V +I L+ + N+ K++ + V G LDRE +LL++A D G P+ IE++D NDNAPVF S + +VS IG + TV+ D D G N I++ + ++ N F I G I ++ S +I+ ASD G ++ A + I + S + P I +H +N+ G
Sbjct: 20 PTFCQCLTKFTVPESAQIGTRIGWISGKREESAAPKYFVVFPDEQTSKFLKVDERSGEISTIAHLDYEKRSKFDIVAVKVEESGE-----TIDILVEVDDENDNAPSFADQVVKLEISEFAQLGTSFALPTV--TDGD-GPKFDVHRFVI------------LQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVF---SRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFAISQSGVITTTASLLPASTH-----DVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENSTLG 357 HSP 11 Score: 65.855 bits (159), Expect = 1.954e-10 Identity = 90/419 (21.48%), Postives = 178/419 (42.48%), Query Frame = 1
Query: 1087 IYITATDGNGRMNETSVDIAI----EDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQ----SKIKFDREKTDSYEFVVTARDNGEPQLN--DSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSL 2301
+ +TATD TSV +++ + D P RF +V+EN K +Q+ + + F + D + +I D F + DRE+ + + +++ ++ + K + ++D NDN P F + + ++ G +GQ+ A D DS NG + Y IL+ ND +++ G IQ + + D +++ +V ARD+G P + V +K+ + P F Y + E ++ L++I+A+++ +N + Y L + KL +++ G +++ +LD E I + + D S I++E +D + APVF S + + + G+++ ++ D D G++G + +S+
Sbjct: 2098 VTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRF-EVMENSK-----IGLQIGNLSGEESREFHYRIQDPEASKIFSI---DKFG----RLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLE---DTSVGTVLQKIRASNRLGMRNDGLLYSLKE-------HQGKLGIDVKT-------GELTLKTHLDWESEPIISMYLSVSDGNGRSAVVPLKIVVEPVD--EFAPVFTKSSYTL---QIPISTPAGESVGQMQAIDEDGGVHGVVKYSI 2481
BLAST of Protocadherin-11 X-linked vs. Ensembl Celegans
Match: cdh-3 (Cadherin-3 [Source:UniProtKB/Swiss-Prot;Acc:P34616]) HSP 1 Score: 100.138 bits (248), Expect = 8.258e-21 Identity = 115/415 (27.71%), Postives = 192/415 (46.27%), Query Frame = 1
Query: 1234 LTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDT--SFDREKIS---VYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL--NSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESY--GESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFR-SLPDRLI---IKASDLG 2439
L TV V++ D+ +F+ + DS + ++ + R D+ + K T S D E+ S V+ + D N +S++ K +I I+D+NDN+PRF ++ F+V EN+ +G V A D+D S+ + Y I+ ++N F ++ G+I+S DRE Y +V A D+G+P+ + V V + D +D P F + + + E GE + Q+ A+D D N + +D GIP G + V +LD E+ S ++ V+ D + T++ + V D+NDNAP+F P F++ EIG+ D+D NG I +S+ + FKI+P ++ S FR LP L+ + A+D G
Sbjct: 1952 LDTVSVREHDEQELAVFKAN-GDSIRYSIVS-RCSDHLEMEKSTGILKTKSSLDAEEYSECLVFIIATTYFD--NKPLSTITKATIKIVDINDNSPRFDQQLYRFNVTENSG-PKLIGHVIARDIDRSS--RVFYEIVGGDANHEFMVTESGQIESVRDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSRIFHVEVPEDVRIGEPVI-----QLSASDADEHSNHRFE---LDGGGEGIPFRVDENT-----------GMVFVNDSLDFEKKQSYRIKVKLTDGAW---LIETSLFVNVKDVNDNAPIFEKP--EYLFISEENSAEIGQ----FHASDMDSENNGKIRYSVTSPY------FKIEPSTGVL--------SRFRQQLPQPLMSLKVTATDHG 2317 HSP 2 Score: 90.1225 bits (222), Expect = 8.255e-18 Identity = 98/343 (28.57%), Postives = 154/343 (44.90%), Query Frame = 1
Query: 1474 INIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHI-VYSILNSNDNF-AISIYGEIQS--------KIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAP---VFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIA 2463
I+++DVNDN+P F ++ + E PIG V A D D NG I Y +++S +S +G +QS K DRE D Y +TA D G P+L+ S + + I DIND P ++ R + N +L + ATD D +N + YR++ P + +S D I V N + E + + +V+A D G P LSTT I++ + N++ P + +PS + F+ V E GKT+ + D D + T + N N++ F + I+ T+K N L +A+D GQ+P + I
Sbjct: 105 IDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPP----NFGIRSLTLNWNGLPNTKLFSLNATDLDSNENSLLTYRILPSGPTS------------EMFSIS-DENILVTQN-NTECLQRCEFVVEARDSGVPPLSTTLNIVVNMEYGNEHEPNINIRFYPS-DYPFIIVQPEDVNGKTLAILSITDSDGPLGANSTIWIENGNEQSIFSLISRQSINIL---TVKHVENANQEQYILEFRAND-GQSPADRIT 424 HSP 3 Score: 83.5741 bits (205), Expect = 8.564e-16 Identity = 149/652 (22.85%), Postives = 274/652 (42.02%), Query Frame = 1
Query: 535 TYPL----PVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNN---IRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLN-----DSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILN-SNDNFAIS-IYGEIQSKIKFDREK-TDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASD 2433
+YPL +A+D D + G+ TY I + N F + + + P +DREE ++ A D G + + + + + V D+NDN PE+ +Y + I E G I+ ++A D+D K+ + Y L E ++ F IN +T ++G +NR R ++ TDG + ++ V+I +ED ND+ P+I+ N V + + I+ + V D DK + F + + ++G++ LK+ ++T V ++ + + ++ + + P FV K+ V E++ + + + +N I YSI++ +D+ + G +++K D E+ ++ F++ L+ +KI DIND +P F++ Y F +TE+ G + + +D+ ++ V Y ++ G N + V+ G I +LDRE S L+V+A DDG P TT+I+ VLD +DNAP F + + V V + IG+ + + D D+ N H E PF++ ++ + +F +S R+ +K +D
Sbjct: 1666 SYPLIIGSSIAEDLDEGQNGLVTYSI--------------LSGNTSLFAVNSTTGDILSLIP-------LDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKISENSKIGSKIIRILATDKD----KDAELQYSLESNDE----ITIPFRINVATGWIT---VAGKVNREENEEFRFFVKVTDGE-KSSKVIVEIHVEDFNDNHPMINDRNSDIFVPDPTRSVEIIHVINVHDLDKSDHLKFSLNNSNLNLSENGEITLKS----------PLQT--------------AVPVRVTVSDDAGHVAFMEYLFHP-HSRKHFPVFVEKLDTVSVREHDE--------QELAVFKANGDSIRYSIVSRCSDHLEMEKSTGILKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQLYRFNVTENSGPKLIGHVIA------RDIDRSSRVFYEIV-----GGDANHEFM--------VTESGQIESVRDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRF----SRIFHVEVPEDVRIGEPVIQLSASDADEHSN----HRFELDGGGEGIPFRVDENTGMVFVNDSLDFEKKQSY--RIKVKLTD 2222 HSP 4 Score: 77.411 bits (189), Expect = 6.171e-14 Identity = 78/276 (28.26%), Postives = 125/276 (45.29%), Query Frame = 1
Query: 1141 IAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGM---FEC--SLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTP-----VFEKDYFFRITESYGESIKNERLEQIKATDKD--LGQNGTV 1929
I + D ND+ P+ I + ++ E + D D+G+NG +E SL ++ I D F ++ DRE +Y++ + +DQG P +SS +I I+D+NDN P F I+ + N + + + A DLDS+ N + Y IL S + SI E + + E EFVV ARD+G P L+ ++ + V ++ N+ P + DY F I + E + + L + TD D LG N T+
Sbjct: 105 IDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTG----KLDRETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNF--GIRSLTLNWNGLPNTKLFSLNATDLDSNENSLLTYRILPSGPTSEMFSISDENILVTQNNTECLQRCEFVVEARDSGVPPLSTTLNIVVNMEYGNEHEPNINIRFYPSDYPFIIVQP--EDVNGKTLAILSITDSDGPLGANSTI 372 HSP 5 Score: 73.559 bits (179), Expect = 9.251e-13 Identity = 84/264 (31.82%), Postives = 120/264 (45.45%), Query Frame = 1
Query: 1618 VYSILNSNDNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIK------------ATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQ-PEGEIIIA 2367
V+ I +++ NF IS + G I + D E +Y F +TA + + V + + D ND P F IT G+ + + LE++ A D D GQNG V Y ++ GN+ L A S G I LDREE S +LL++A D G PSLS T+ I+I V D+NDN P F S F+ +S +IG I + D D+ + + +SL SN PF+I G I +A
Sbjct: 1588 VFRIQDNDYNFTISPFDGTIFTNSPLDFENIKTYRFNITAGKS-------TSQVIIHVTDENDEAPRF-------IT---GDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILS-------GNTSLFA------VNSTTGDILSLIPLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSS---YFIKISENSKIGSKIIRILATDKDK--DAELQYSL-ESNDEITIPFRINVATGWITVA 1815 HSP 6 Score: 72.7886 bits (177), Expect = 1.534e-12 Identity = 51/159 (32.08%), Postives = 84/159 (52.83%), Query Frame = 1
Query: 1489 VNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNF-----AISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLG-QNGTVKYRLID 1947
+N ++P + +I HV+EN PIG+ G+++A D DS +G + Y IL +D++ S G ++S FD EK SY F A+D G P + + I+D+ND P F Y+ G+S NE + ++A D D+ +N ++Y L++
Sbjct: 626 LNQHSP--ICQITEIHVLENAPIGTIFGRIQARDEDSGLSGVVSYKILTKSDDYDGIFHLDSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTPSKTTNCPATIFIEDVNDNVPKFGSRYYTATIS--GKS--NETVAIVQANDNDVDVKNQKLQYHLLN 778 HSP 7 Score: 71.633 bits (174), Expect = 4.186e-12 Identity = 90/319 (28.21%), Postives = 141/319 (44.20%), Query Frame = 1
Query: 949 NGLVSYQLS---DR-TEDRKIV-------SQIFYINGNKLHLTNNRISGLINRN------NIRIY---ITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFG-KVLENQKQ---KIILTTVQVKDEDKGRNGMFECS-LNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY-----GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPV 1815
NG + +S DR TE KIV +F I N + T + G I N NI+ Y ITA + V I + D ND P + KVLE +I+ + +D D+G+NG+ S L+ + L N D ++ + DRE+ S++ + I+ D G P++S+ K I++ D+NDN P F + EN+ IGS + +R + D + + YS L SND I G I K +RE+ + + F V D GE + ++V++ ++D ND P+
Sbjct: 1557 NGTFEFNISETADRFTEVGKIVILGAGLEGSVFRIQDNDYNFTISPFDGTIFTNSPLDFENIKTYRFNITAGKSTSQ-----VIIHVTDENDEAPRFITGDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILSGNTSLFAVNSTTGDILSLIPL--------DREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKISENSKIGSKI--IRILATDKDKDAELQYS-LESNDEITIPFRINVATGWITVAGKVNREENEEFRFFVKVTD-GEK--SSKVIVEIHVEDFNDNHPM 1856 HSP 8 Score: 69.3218 bits (168), Expect = 1.800e-11 Identity = 82/296 (27.70%), Postives = 122/296 (41.22%), Query Frame = 1
Query: 1087 IYITAT---DGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIY---KIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHV--VENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRL 1941
++I AT D T I I D ND+ P V EN K+I V +D D+ +E D+ + F + +IE+ D DRE S Y + ++ +D G P + ++D +DNAPRF ++FHV E+ IG V Q+ A D D +N + + + + G + D EK SY V D G + S+ V VK D+ND P+FEK + I+E I Q A+D D NG ++Y +
Sbjct: 2012 VFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQLYRFNVTENSGPKLI-GHVIARDIDRSSRVFYEIVGGDA----------NHEFMVTESGQIESVRD--LDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFS---RIFHVEVPEDVRIGEPVIQLSASDADEHSNHR--FELDGGGEGIPFRVDENTGMVFVNDSLDFEKKQSYRIKVKLTD-GAWLIETSLFVNVK--DVNDNAPIFEKPEYLFISEENSAEIG-----QFHASDMDSENNGKIRYSV 2281 HSP 9 Score: 60.8474 bits (146), Expect = 6.689e-9 Identity = 64/231 (27.71%), Postives = 103/231 (44.59%), Query Frame = 1
Query: 1678 SKIKFDREKTDSYEFVVTARDNGEPQLNDSMVV----------KVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTV-KYRLID-------VKPIGIPGNSKLKAELRNLIKVSFDGAI--SVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINS 2310
SKIKFD + + E V++ + E + M++ + + D+ND +P+F D + E + R++ ATD D G+NGT+ KY L+D + P GI V DG + V G LDRE + + A D G P LS++ + I +LD+NDN P F S +N+ + + ++ DLD N +T+ ++ S
Sbjct: 64 SKIKFDEQ---TLELSVSSPLDRESENAIDMLIITSPPSIIHILIDVLDVNDNSPIFPID--VQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGI---------------VQSDGFLFLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNFGIRSLTLNWNGLP-----NTKLFSLNATDLDSNENSLLTYRILPS 269 HSP 10 Score: 60.4622 bits (145), Expect = 1.028e-8 Identity = 93/378 (24.60%), Postives = 157/378 (41.53%), Query Frame = 1
Query: 712 LEIIKNIDREEFVS-FVFILIATDFGNQTGSCXXXXXXXXXXXX--APEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFY--INGNKLHLTNNRISGLI---------NRNNIRIYITATDGNG--RMNETSVDIAIEDCNDHPPVISIANRFGKVL-----ENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKV 1782
L+ ++D EE+ VFI+ T F N+ S + V+ N +P + + Y+ N+ E I +IA D D S++FY + G+ H SG I ++ + + A D R T+V + + D +D+ P RF ++ E+ + + + D D+ N FE D G + R D+N + + + S D EK Y +++K D +S+ +N+ DVNDNAP F +F EN+ + +GQ A D+DS NNG I YS+ ++ F I + S+ + + VTA D+G P+L +++ +
Sbjct: 1996 LKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQLYRFNVTENSGPKLIGHVIARDIDRS---------------------SRVFYEIVGGDANHEFMVTESGQIESVRDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAP------RFSRIFHVEVPEDVRIGEPVIQLSASDADEHSNHRFEL---DGGGEGIP-FRVDENTGM----VFVNDSLDFEKKQSYRIKVKLTDGAWLIETSL---FVNVKDVNDNAPIFEKPEYLFISEENS---AEIGQFHASDMDSENNGKIRYSV--TSPYFKIEPSTGVLSRFR-QQLPQPLMSLKVTATDHGVPRLQKTVLAHL 2329 HSP 11 Score: 56.6102 bits (135), Expect = 1.299e-7 Identity = 57/204 (27.94%), Postives = 91/204 (44.61%), Query Frame = 1
Query: 1063 LINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDT-----SFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLD-SSNNGHIVYSILNSNDNFAI 1656
L+NRN + I + + ++ N H P+ I VLEN I +Q +DED G +G+ S K+ K+ DD I+ +++ + +FD EK YT E + D G P+ ++ +I I DVNDN P+F + + + + TV V+A D D N + Y +LN +D F +
Sbjct: 608 LVNRNTTQTSI-------------ITLIVKPLNQHSPICQITEI--HVLENAPIGTIFGRIQARDEDSGLSGVV------SYKILTKS---DDYDGIFHLDSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTPSKTTNCPATIFIEDVNDNVPKFGS--RYYTATISGKSNETVAIVQANDNDVDVKNQKLQYHLLNYHDFFQL 785
BLAST of Protocadherin-11 X-linked vs. Ensembl Fly
Match: kug (gene:FBgn0261574 transcript:FBtr0346077) HSP 1 Score: 158.688 bits (400), Expect = 1.349e-38 Identity = 176/597 (29.48%), Postives = 282/597 (47.24%), Query Frame = 1
Query: 712 LEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXX--XXXXXXXXAPEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRM--NETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDN--APRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSN-NGHIVYSILNSNDN--FAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIG-IPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIA 2463
L+II +DRE +V + D GN T S + + + DVNDN P K + E G ++ + A D D + N V+Y LS D F +N L N+ ++N ++ITA DG + +E V + ++D ND+ PV + KV E+ + +L ++ DED G N + SL + + + + R D + + + Y D E V+ + + +D G+P+++S I IIDVN+N AP F + + V EN P G+ V V A D+D+ + N I YSI + FA++ G I S + D E + Y + A+D L++ + V +++++ ND P+ +K Y+ +TE+ S++N + +KA D D+ T+ Y ++ +G +SK +IK + LDRE + L V D+G P LS+T+ I++ VLD+NDN+P F + V V + ++I V D D G NG IT+S I S K +N F+I + G I IA + + F + IKA D G K+ A
Sbjct: 829 LQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDAD--SGINAQVTYALSVECSD-------FTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQ-DEELFRIDKHTGAIRTQGY----LDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEA---SVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSK-----TGVIK-------TTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEF---DQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYS-IKSGKGKN-KFRIDSQRGHIHIAKPLDSDNEF-----EIHIKAEDNGIPKKSQTA 1386 HSP 2 Score: 150.214 bits (378), Expect = 5.467e-36 Identity = 177/621 (28.50%), Postives = 283/621 (45.57%), Query Frame = 1
Query: 661 FFQIKNPKSKQEEIYPSLE--IIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDIL-ELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNI---RIYITATDGNGRMNE--TSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI---SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKAS--DLGQNPKNNIATLYIRYI 2484
FF + K Q +I S E I K +DRE+ + + +IATD G T V + V D+NDN P K Y ++ E S G L E+ A D D + + LS + D F I L +++ ++R ++ DG E + + I + D ND+ P+ S+A V E+ + ++T V D+D G N + SL N + + I ++ S DRE IS++ + +K D G P + S+ ++NI+D+NDN P F + ++EN G+ V +V A +D N I Y I++ N+ S G++ D E + Y + A D G P L+++ V + I DIND +P F ++ +RI + + ++ L+ +KATD+D NG V Y + IG + + +N G ISV LDRE IS L +QA D G P + I I +LD NDNAP+ F S+N + V + +G T K D D+ N T ++ + E F+++ +G + T F++ +L D +I+ D G P + A + ++ I
Sbjct: 3003 FFIVSGDKQAQFQIGKSGELFIAKPLDREQLMFYNLSIIATD-GKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFD----FQSKLRFYLSGKGADD------FSIGKESGIL---KVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGE---NHDYFKISKSTGIIRLHK----SLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQN-LYRINVNEDIFVGSKILD-VKATDEDSDVNGLVTYNIERGDNIG-----QFSIDPKN-------GTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPI--FSSSNYSVV-LQENRLLGYVFLTFKISDADETPN-TTPYTFDIRSGNEGGLFRLEQDGSL---RTASRFNH--NLQDEFVIQVRVFDNGTPPLYSDAWVVVKII 3579 HSP 3 Score: 144.05 bits (362), Expect = 4.066e-34 Identity = 122/422 (28.91%), Postives = 197/422 (46.68%), Query Frame = 1
Query: 1243 VQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDN--APVFLFPSNNMNFV---NVSVEWEIGKTICTVKTKDLDQ-GINGTITHSLINSNKRENFPFKIQPEGEII-IAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIR 2478
++ KD D G NG +++D ++ R D + +I Y DRE+ + Y + I D GNP S+ + I I+DVNDN P + F + E+ IG+ V + A D DS N + Y++ +F + + G ++ DREK D+Y +TA+D G P L+ +V V + D+ND PVF ++Y F++ E + L I+A D+D+G N +++ L K + + L ++ GAI G LD E L+V A D G PSL++ +I+I ++D+N+N AP F +FV V G + V +D+D +N IT+S+ + F + +G I ++ E NF L + A D P +N +YI+
Sbjct: 794 IEAKDRDLGYNGKLVFAISDGDYDSV--FRIDPDRGELQIIGY----LDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLP---RGTVLAVIEAVDEDIGPNAEIQFSL------------KEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEF------DDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLG--IFAVNDQGSITSLSQLDAETKNFY----WLTLCAQDCAIVPLSNCVEVYIQ 1182 HSP 4 Score: 102.834 bits (255), Expect = 1.514e-21 Identity = 93/359 (25.91%), Postives = 157/359 (43.73%), Query Frame = 1
Query: 1129 TSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNG---MFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLE-----QIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPV 2172
+V + I D ND+PP S+ K+LEN + V D G N F S N+ GK + + D + + D E Y + I+ +D G P +S+ +I+I+D+NDN+P F+ + +V E+ +GS + V+A D DS NG + Y+I ++ SI G I DRE Y + A D G+PQ +S+ + + I D ND P+F + +Y ++ RL K +D D N T Y D++ GN L ++ DG++ + + V+ FD+G P L + +++++++ + P+
Sbjct: 3257 ATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGD---------LVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFS-------SSNYSVVLQENRLLGYVFLTFKISDADETPN-TTPYTF-DIRS----GNEG------GLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPI 3587 HSP 5 Score: 102.834 bits (255), Expect = 1.704e-21 Identity = 133/473 (28.12%), Postives = 190/473 (40.17%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL-NSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSF-----DGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSIGKKSHS 2535
V I + D ND+ P V EN ++ I L V D D G NG L +S N++NI FD IY TS DRE S Y ++ D G+P + +I I+D NDNAP F I+ V EN G+ + + +D D + + + F I GE+ DRE+ Y + A D + V++ ++DIND TP K R S ESI ++ L++VK I SKL+ L F G + V LDRE +L+ D + + III V D+NDN P+F S V+V + ++ I V D D G+N I +SL+ N FKI II H + L +KA D G ++IAT+ + + N NP + +S
Sbjct: 2846 VLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYL-ESDTENIQNI-FD--IDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQFQIGKSGELFIAKPLDREQLMFYNLSIIATDG---KFTAKANVEIDVKDINDNTPYCLKP---RYHISTNESI-------------------SIGTTLVEVKAIDFDFQSKLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIF---SMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDY---FKISKSTGIIRLHKSLDRETISLF--NLTVKAEDCGVPKLHSIATVAVNILD--INDNPPEFSMRQYS 3279 HSP 6 Score: 102.064 bits (253), Expect = 2.409e-21 Identity = 147/554 (26.53%), Postives = 232/554 (41.88%), Query Frame = 1
Query: 844 PEWTKDNYKVNIQE-CQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVS--QIFYINGNKLHLTNNRISGLINRNNIRIYITATDGN-GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSL--NDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYG---------ESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTT--IIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICT--VKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASD 2433
P++ KD Y VNI E + E I++L A DRD+ + + Y L T+D ++ +I I+GN + R+ +I I G G+ N + + + D NDH P + KV E+ L V+ D D G N + S+ + G + D F I + + + KI Y +++K VD GNP +SS I + ++ P+F + EN PIG+ V QV A S I ++I++ N N + I G I D E + V + +++ + I D ND P F + +Y + ES +S K+ Q+K D D+G NG V+Y ++D +N K+ S GAI + LD E + V D G P L +TTT + I V+++ND PVF N +NV++ + + V KD D N T+ +++ N E F+I+ II + +N L ++ASD
Sbjct: 1504 PQFAKDVYHVNISENIEEESVIMQLHATDRDE----DKKLFYHLH-ATQDPSSLALFRIDSISGNVI--VTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSV----FEIDPTFGIITLAG----NLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSS-----IFFNIISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNII--IHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVK--DADVGVNGMVEYHIVD-------------DLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVF-----NERELNVTLFLPTFENVFVRQVSAKDAD---NDTLRFDIVDGNTNEC--FQIEKYTGIITTRNFEILNNENDRDYALHVRASD 2010 HSP 7 Score: 102.064 bits (253), Expect = 3.025e-21 Identity = 71/263 (27.00%), Postives = 122/263 (46.39%), Query Frame = 1
Query: 1399 ISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVS-FDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP 2184
++ Y ++ D+G P S SI II+ + N P F + ++E+ P G+ + ++ + N +SI D+F IS GE+ + DRE+ +S+ +V A + P V + ++D ND P F+ ++ E + + L ++ ATD D G NG ++Y L ++N+ + + G I++ +LDRE S V A D+G+P + I+++D NDNAPVF P
Sbjct: 2726 VNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMI-----GNYTFKFSIAADQDHFMISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVIS--LVKVSATDADTGPNGDIRYYL-----------ESDTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLP 2970 HSP 8 Score: 93.2041 bits (230), Expect = 1.446e-18 Identity = 111/410 (27.07%), Postives = 181/410 (44.15%), Query Frame = 1
Query: 1111 NGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITE--SYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
N R TS+DI++ D ND+ P+ + V + + I+ V+ D D NG L K N + + D I+ + + +R Y + + D SS + +ID + P F + V E+ + S + +++ +S ++Y+I + + +F I G I + D EK S++ + A D+ + +V+ V I D+NDC P E D Y I E S+G I +I ATD D G N + Y ++ I NS+L I V+ DG + + LD E+I ++V D G PSLS+ + + I V DLNDNAP F+ PS F VSV G+ + K D D ++ + ++ N+ + +
Sbjct: 2118 NVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELK---KGNGELFKLDRKSGELSIKQHVE-GHNRN----YELTVAAYDGAITPCSSEAPLQVKVID--RSMPVFEKQFYTVSVKEDVEMYSALSV--SIEAESPLGRSLIYTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLS-GVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQIL-----KINATDNDSGANAKLSYY---IESINGQNNSELF-----YIDVT-DGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPS---YFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTY 2497 HSP 9 Score: 87.0409 bits (214), Expect = 1.050e-16 Identity = 109/440 (24.77%), Postives = 183/440 (41.59%), Query Frame = 1
Query: 1093 ITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPD-----TSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIK----ATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSF-----DGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFL-------FPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI 2340
I+ TDG T++ + + D ND+PP + + EN +++ ++ + D D+ + + +L + + A+++I++ D EK + + + + DQG P + K +N+ D ND+ P F KI V E+ IGS + +VRA+D DS +N I YSI+ N I +G I + K Y V A D G P L+ + V + + + P F + +I E E + T + ++ + +I GN I SF G I + GN+D E I L V+ + + S+ III +LD NDN P F+ P + V + K T++ KD D G+NG + + +++ + +NF FKI
Sbjct: 1479 ISVTDGTFTAF-TNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFY----------HLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTN-----------NIAIEIFENLPIGTFVTQVTARSSSSIFFNIIS-------GN----------INESFRINPSTGVIVINGNIDYESIKVFNLTVKGTN--MAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVD-DLAKNF-FKI 1875 HSP 10 Score: 81.2629 bits (199), Expect = 6.432e-15 Identity = 139/609 (22.82%), Postives = 256/609 (42.04%), Query Frame = 1
Query: 646 GNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNT-KNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATD----GNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFD-DNFA-IYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQ-KFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQS-KIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKI--QDINDCTPVF---------EKDYFFRITESYGESIKN-------ERLEQIKATDKDLGQN----------------------GTVKYRLIDVKPIGIPGNSKL-----KAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSL 2301
GN F +K ++K +E Y L +++++ F+ + L+A D G + +V + + + N P +T++ Y+V+I E + +I DP+ KN LV ++ E + F IN + L + +++ + ++A D G+ + + V I+++D ND+ P+ N+ + EN + + KD D G N S+ NL + F+ D+F+ I K + D F+ K + Y + I+ D G P + K SI + D+NDN P+F V ++ P+G+ V A+D D+ + I Y + + N++ ++ S I D +KT ++ +D +++ V + +D+ + + E R+ E+ + KN + T GQN TV + I+ K + N KL + ++ ++ D G + + G LDRE + L + +D G P+ ST+ + I +LD+NDN PV + ++ IG + + D D GIN +T++L
Sbjct: 332 GNPDGTFLLKAAETK-DEYYIELNQFAHLNQQHFI-YNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPIN--MPVIRLKVSDPDLGKNALVYLEIVGGNEGDE-----FRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSI-----ANLNAVPFEIDHFSGIVKTTSLLD--FETMKRN-YELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGD--IISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAW--IEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVI---QKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYAL 916 HSP 11 Score: 80.4925 bits (197), Expect = 1.040e-14 Identity = 114/435 (26.21%), Postives = 182/435 (41.84%), Query Frame = 1
Query: 1243 VQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPA--MSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSND-NFAISIYGEI---QSKIKFDREKTDSYEFVVTARDNGEPQLNDSMV-VKVKIQDINDCTPVFEKDYFFRITESYGESIKNERL--EQIKATDKDLGQNGTVKYRLIDVKPIGI------PGNSKLKAELR------NLIKVS------FDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLND-------NAPVF----LFPS------NNMNFVNVSVEWEI------GKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEI-IIAHTMKEFSN 2391
++V D D G+N + + + + I D Y D EK S YT+ + +DQ N S K I++ D+NDN P F N K+ + ENN GS V ++ A D DS N +I YSI N N F I + I S + F+ K + YE ++ A D G P + + + + ++DIND P FE+ YG+ K+ + E + D + YRL D G G+ + +L+ ++KVS F + + +L E++ ++ F + + E L L + + VF L PS + FVN E I G+T+ ++ KD D G NG + ++ S+ + F+I P+ GE+ II + +E N
Sbjct: 422 LKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGM------LYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMKRN-YELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFER------VNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAI--SDGDYDSVFRIDPDRGELQIIGYLDRERQN 841 HSP 12 Score: 74.3294 bits (181), Expect = 7.099e-13 Identity = 144/552 (26.09%), Postives = 227/552 (41.12%), Query Frame = 1
Query: 310 FSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTT--YPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNG--RMNETSVDIAIEDCNDHPPVISIANRFG-KVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDT-----SFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSS-NNGHIVYSILNSNDN--FAISIYGEIQSKIKFDREKTDSYEFVVTAR--DNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRIT-ESYGESIKNERLEQIKATDKD 1908
FS+ + SG L V S LDRET T KL H + + V +I +N+PI + Y + V +D K + + + G++++ + +G N +F+I SK I + + K++DRE F + A D G TV V + D+NDN PE++ Y I E + G ++ ++ A D N + Y + E K F ++ L N + I A DG N V+I+I D ND+ P + N + V E+ + V+ DED NG+ NI DN + I+ T DRE IS YT+EI+ DQG+P + +INI+D NDNAP F + + EN +G + D D + N + I + N+ F + G +++ +F+ D EFV+ R DNG P L V VKI + + P+ +T S+ + + ++ A+D+D
Sbjct: 3112 FSIGKESGILKVASALDRET-------TPKYKLV----AHVQDGKDFTQECFS-----EIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKI----SKSTGI---IRLHKSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSID--IGVNADIHYFIMSGNEQGK-----FKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTF-LQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVT-----------YNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQD--EFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTP---LEVTINSFEDDFSGAFIGKVHASDQD 3616 HSP 13 Score: 71.633 bits (174), Expect = 4.571e-12 Identity = 82/333 (24.62%), Postives = 141/333 (42.34%), Query Frame = 1
Query: 1384 FDREKISVYTVEIKCVDQGNPAMSS-----MQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTD------------SYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVE--WEIGKTICTVKTKDLDQGINGTITHSLINSNKREN 2325
FDRE +Y + ++ M+S + I+++DVNDN P FVN V ++P G+ + QV+A+DLDS+ NG + Y + N GE+ K DR+ + +YE V A D + ++VK+ I+ PVFEK + Y S+K E +E A + + LI + +E ++ G+I V LD E+ISS + ++A D + + + ++D+ND +P + N+++ G I + D D G N +++ + + N + N
Sbjct: 2093 FDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGN--------GEL---FKLDRKSGELSIKQHVEGHNRNYELTVAAYDGAITPCSSEAPLQVKV--IDRSMPVFEKQF-------YTVSVK-EDVEMYSALSVSIEAESPLGRSLI----------YTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRA-TDSLSGVYAEVVLSVSIMDVND-----CYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNN 2388 HSP 14 Score: 71.2478 bits (173), Expect = 6.967e-12 Identity = 80/307 (26.06%), Postives = 139/307 (45.28%), Query Frame = 1
Query: 1384 FDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILN--SNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEP---QLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNER----LEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQ 2271
DRE + + +E+ D G+P +SS + ++++D+NDN+P F ++ V + + ++ QV A+D DS NG I YSI + + F I S G I D + + +E + A DNG P Q +V V + + P+ + + +E+ + +N++ + QI A D D N + Y + + GN N + D G I + LD E S L + D + + T ++++V+D+NDN P F + ++ VN+S E I + D D+
Sbjct: 1257 LDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSD--NEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVR----KTSENVVDLTENDKPGFLVTQILAVDDD---NDQLWYNISN-------GNDD------NTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAF---TNLLVQVIDINDNPPQF---AKDVYHVNISENIEEESVIMQLHATDRDE 1535 HSP 15 Score: 59.6918 bits (143), Expect = 2.229e-8 Identity = 88/391 (22.51%), Postives = 160/391 (40.92%), Query Frame = 1
Query: 1300 DSGKLNLKNIRFDDNFAIYKIETYPD-TSFDREKISVYTVEIKCV----DQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNG-----EPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTV-KYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREE-ISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASD 2433
D KL + +FA I T + +REK Y + +K D+ + + I ++D ND +P F + E+ P ++ +V A D D NG I YS+L ++ FAI GEI + + +E V A D G + V + ++ +N P F +T + I ++ DKD G NG + + ++D P G LKA K + ++ + +L+++ I ++ LL + D G P ++ I++ + N P+F + + V++ I + +K D D G N + ++ N+ + F+I P+ ++ +T K+ + L + A D
Sbjct: 108 DKEKLFKAEEKLVGDFAFLAIRTRTNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYG----IVRVNDKDTGINGNIGRLEIVDGNP---DGTFLLKAA---ETKDEYYIELNQFAHLNQQHFIYNLTLLAE--DLGTPRRFAYKSVPIQIKPESKNIPIF---TQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDE--FRINPDSGML--YTAKQLDAEKKSSYTLTVSAID 479 HSP 16 Score: 59.3066 bits (142), Expect = 2.943e-8 Identity = 99/421 (23.52%), Postives = 165/421 (39.19%), Query Frame = 1
Query: 1087 IYITATDG-NGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIET-----YPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDG----YPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLI 2304
+ I ATD +G E + ++I D ND P I + EN + + D D G N +++I +N ++ I+ Y T D E+I + + + D G+P++SS I + D+NDNAP FV V G V +A D D S+ + Y I+ N+ SI G I + + S ++ D +K+ + N +P+F++ Y ++ E+ + + +KA+D D G + Y ++ E++ + + G I+ DRE+ +L++ D G + SL +NDN P FL M VS E +TI TVK KD D NG++ ++
Sbjct: 2310 VSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKL--------SYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAY---ARLKISLLPENVYSPLFDQSTYEAQVPENL---LHGHNIITVKASDGDFGTYANLYYEIV-------------SEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKFGFASLKVIVVD------VNDNVPYFLLKEYKMV---VSTTVEANQTILTVKAKDDDIVDNGSVHFQIV 2694
BLAST of Protocadherin-11 X-linked vs. Ensembl Fly
Match: kug (gene:FBgn0261574 transcript:FBtr0332721) HSP 1 Score: 158.688 bits (400), Expect = 1.349e-38 Identity = 176/597 (29.48%), Postives = 282/597 (47.24%), Query Frame = 1
Query: 712 LEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXX--XXXXXXXXAPEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRM--NETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDN--APRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSN-NGHIVYSILNSNDN--FAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIG-IPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIA 2463
L+II +DRE +V + D GN T S + + + DVNDN P K + E G ++ + A D D + N V+Y LS D F +N L N+ ++N ++ITA DG + +E V + ++D ND+ PV + KV E+ + +L ++ DED G N + SL + + + + R D + + + Y D E V+ + + +D G+P+++S I IIDVN+N AP F + + V EN P G+ V V A D+D+ + N I YSI + FA++ G I S + D E + Y + A+D L++ + V +++++ ND P+ +K Y+ +TE+ S++N + +KA D D+ T+ Y ++ +G +SK +IK + LDRE + L V D+G P LS+T+ I++ VLD+NDN+P F + V V + ++I V D D G NG IT+S I S K +N F+I + G I IA + + F + IKA D G K+ A
Sbjct: 829 LQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDAD--SGINAQVTYALSVECSD-------FTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQ-DEELFRIDKHTGAIRTQGY----LDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEA---SVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSK-----TGVIK-------TTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEF---DQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYS-IKSGKGKN-KFRIDSQRGHIHIAKPLDSDNEF-----EIHIKAEDNGIPKKSQTA 1386 HSP 2 Score: 150.214 bits (378), Expect = 5.467e-36 Identity = 177/621 (28.50%), Postives = 283/621 (45.57%), Query Frame = 1
Query: 661 FFQIKNPKSKQEEIYPSLE--IIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDIL-ELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNI---RIYITATDGNGRMNE--TSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI---SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKAS--DLGQNPKNNIATLYIRYI 2484
FF + K Q +I S E I K +DRE+ + + +IATD G T V + V D+NDN P K Y ++ E S G L E+ A D D + + LS + D F I L +++ ++R ++ DG E + + I + D ND+ P+ S+A V E+ + ++T V D+D G N + SL N + + I ++ S DRE IS++ + +K D G P + S+ ++NI+D+NDN P F + ++EN G+ V +V A +D N I Y I++ N+ S G++ D E + Y + A D G P L+++ V + I DIND +P F ++ +RI + + ++ L+ +KATD+D NG V Y + IG + + +N G ISV LDRE IS L +QA D G P + I I +LD NDNAP+ F S+N + V + +G T K D D+ N T ++ + E F+++ +G + T F++ +L D +I+ D G P + A + ++ I
Sbjct: 3003 FFIVSGDKQAQFQIGKSGELFIAKPLDREQLMFYNLSIIATD-GKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFD----FQSKLRFYLSGKGADD------FSIGKESGIL---KVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGE---NHDYFKISKSTGIIRLHK----SLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQN-LYRINVNEDIFVGSKILD-VKATDEDSDVNGLVTYNIERGDNIG-----QFSIDPKN-------GTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPI--FSSSNYSVV-LQENRLLGYVFLTFKISDADETPN-TTPYTFDIRSGNEGGLFRLEQDGSL---RTASRFNH--NLQDEFVIQVRVFDNGTPPLYSDAWVVVKII 3579 HSP 3 Score: 144.05 bits (362), Expect = 4.066e-34 Identity = 122/422 (28.91%), Postives = 197/422 (46.68%), Query Frame = 1
Query: 1243 VQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDN--APVFLFPSNNMNFV---NVSVEWEIGKTICTVKTKDLDQ-GINGTITHSLINSNKRENFPFKIQPEGEII-IAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIR 2478
++ KD D G NG +++D ++ R D + +I Y DRE+ + Y + I D GNP S+ + I I+DVNDN P + F + E+ IG+ V + A D DS N + Y++ +F + + G ++ DREK D+Y +TA+D G P L+ +V V + D+ND PVF ++Y F++ E + L I+A D+D+G N +++ L K + + L ++ GAI G LD E L+V A D G PSL++ +I+I ++D+N+N AP F +FV V G + V +D+D +N IT+S+ + F + +G I ++ E NF L + A D P +N +YI+
Sbjct: 794 IEAKDRDLGYNGKLVFAISDGDYDSV--FRIDPDRGELQIIGY----LDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLP---RGTVLAVIEAVDEDIGPNAEIQFSL------------KEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEF------DDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLG--IFAVNDQGSITSLSQLDAETKNFY----WLTLCAQDCAIVPLSNCVEVYIQ 1182 HSP 4 Score: 102.834 bits (255), Expect = 1.514e-21 Identity = 93/359 (25.91%), Postives = 157/359 (43.73%), Query Frame = 1
Query: 1129 TSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNG---MFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLE-----QIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPV 2172
+V + I D ND+PP S+ K+LEN + V D G N F S N+ GK + + D + + D E Y + I+ +D G P +S+ +I+I+D+NDN+P F+ + +V E+ +GS + V+A D DS NG + Y+I ++ SI G I DRE Y + A D G+PQ +S+ + + I D ND P+F + +Y ++ RL K +D D N T Y D++ GN L ++ DG++ + + V+ FD+G P L + +++++++ + P+
Sbjct: 3257 ATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGD---------LVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFS-------SSNYSVVLQENRLLGYVFLTFKISDADETPN-TTPYTF-DIRS----GNEG------GLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPI 3587 HSP 5 Score: 102.834 bits (255), Expect = 1.704e-21 Identity = 133/473 (28.12%), Postives = 190/473 (40.17%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL-NSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSF-----DGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSIGKKSHS 2535
V I + D ND+ P V EN ++ I L V D D G NG L +S N++NI FD IY TS DRE S Y ++ D G+P + +I I+D NDNAP F I+ V EN G+ + + +D D + + + F I GE+ DRE+ Y + A D + V++ ++DIND TP K R S ESI ++ L++VK I SKL+ L F G + V LDRE +L+ D + + III V D+NDN P+F S V+V + ++ I V D D G+N I +SL+ N FKI II H + L +KA D G ++IAT+ + + N NP + +S
Sbjct: 2846 VLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYL-ESDTENIQNI-FD--IDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQFQIGKSGELFIAKPLDREQLMFYNLSIIATDG---KFTAKANVEIDVKDINDNTPYCLKP---RYHISTNESI-------------------SIGTTLVEVKAIDFDFQSKLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIF---SMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDY---FKISKSTGIIRLHKSLDRETISLF--NLTVKAEDCGVPKLHSIATVAVNILD--INDNPPEFSMRQYS 3279 HSP 6 Score: 102.064 bits (253), Expect = 2.409e-21 Identity = 147/554 (26.53%), Postives = 232/554 (41.88%), Query Frame = 1
Query: 844 PEWTKDNYKVNIQE-CQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVS--QIFYINGNKLHLTNNRISGLINRNNIRIYITATDGN-GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSL--NDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYG---------ESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTT--IIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICT--VKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASD 2433
P++ KD Y VNI E + E I++L A DRD+ + + Y L T+D ++ +I I+GN + R+ +I I G G+ N + + + D NDH P + KV E+ L V+ D D G N + S+ + G + D F I + + + KI Y +++K VD GNP +SS I + ++ P+F + EN PIG+ V QV A S I ++I++ N N + I G I D E + V + +++ + I D ND P F + +Y + ES +S K+ Q+K D D+G NG V+Y ++D +N K+ S GAI + LD E + V D G P L +TTT + I V+++ND PVF N +NV++ + + V KD D N T+ +++ N E F+I+ II + +N L ++ASD
Sbjct: 1504 PQFAKDVYHVNISENIEEESVIMQLHATDRDE----DKKLFYHLH-ATQDPSSLALFRIDSISGNVI--VTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSV----FEIDPTFGIITLAG----NLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSS-----IFFNIISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNII--IHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVK--DADVGVNGMVEYHIVD-------------DLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVF-----NERELNVTLFLPTFENVFVRQVSAKDAD---NDTLRFDIVDGNTNEC--FQIEKYTGIITTRNFEILNNENDRDYALHVRASD 2010 HSP 7 Score: 102.064 bits (253), Expect = 3.025e-21 Identity = 71/263 (27.00%), Postives = 122/263 (46.39%), Query Frame = 1
Query: 1399 ISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVS-FDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP 2184
++ Y ++ D+G P S SI II+ + N P F + ++E+ P G+ + ++ + N +SI D+F IS GE+ + DRE+ +S+ +V A + P V + ++D ND P F+ ++ E + + L ++ ATD D G NG ++Y L ++N+ + + G I++ +LDRE S V A D+G+P + I+++D NDNAPVF P
Sbjct: 2726 VNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMI-----GNYTFKFSIAADQDHFMISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVIS--LVKVSATDADTGPNGDIRYYL-----------ESDTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLP 2970 HSP 8 Score: 93.2041 bits (230), Expect = 1.446e-18 Identity = 111/410 (27.07%), Postives = 181/410 (44.15%), Query Frame = 1
Query: 1111 NGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITE--SYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
N R TS+DI++ D ND+ P+ + V + + I+ V+ D D NG L K N + + D I+ + + +R Y + + D SS + +ID + P F + V E+ + S + +++ +S ++Y+I + + +F I G I + D EK S++ + A D+ + +V+ V I D+NDC P E D Y I E S+G I +I ATD D G N + Y ++ I NS+L I V+ DG + + LD E+I ++V D G PSLS+ + + I V DLNDNAP F+ PS F VSV G+ + K D D ++ + ++ N+ + +
Sbjct: 2118 NVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELK---KGNGELFKLDRKSGELSIKQHVE-GHNRN----YELTVAAYDGAITPCSSEAPLQVKVID--RSMPVFEKQFYTVSVKEDVEMYSALSV--SIEAESPLGRSLIYTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLS-GVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQIL-----KINATDNDSGANAKLSYY---IESINGQNNSELF-----YIDVT-DGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPS---YFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTY 2497 HSP 9 Score: 87.0409 bits (214), Expect = 1.050e-16 Identity = 109/440 (24.77%), Postives = 183/440 (41.59%), Query Frame = 1
Query: 1093 ITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPD-----TSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIK----ATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSF-----DGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFL-------FPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI 2340
I+ TDG T++ + + D ND+PP + + EN +++ ++ + D D+ + + +L + + A+++I++ D EK + + + + DQG P + K +N+ D ND+ P F KI V E+ IGS + +VRA+D DS +N I YSI+ N I +G I + K Y V A D G P L+ + V + + + P F + +I E E + T + ++ + +I GN I SF G I + GN+D E I L V+ + + S+ III +LD NDN P F+ P + V + K T++ KD D G+NG + + +++ + +NF FKI
Sbjct: 1479 ISVTDGTFTAF-TNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFY----------HLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTN-----------NIAIEIFENLPIGTFVTQVTARSSSSIFFNIIS-------GN----------INESFRINPSTGVIVINGNIDYESIKVFNLTVKGTN--MAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVD-DLAKNF-FKI 1875 HSP 10 Score: 81.2629 bits (199), Expect = 6.432e-15 Identity = 139/609 (22.82%), Postives = 256/609 (42.04%), Query Frame = 1
Query: 646 GNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNT-KNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATD----GNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFD-DNFA-IYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQ-KFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQS-KIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKI--QDINDCTPVF---------EKDYFFRITESYGESIKN-------ERLEQIKATDKDLGQN----------------------GTVKYRLIDVKPIGIPGNSKL-----KAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSL 2301
GN F +K ++K +E Y L +++++ F+ + L+A D G + +V + + + N P +T++ Y+V+I E + +I DP+ KN LV ++ E + F IN + L + +++ + ++A D G+ + + V I+++D ND+ P+ N+ + EN + + KD D G N S+ NL + F+ D+F+ I K + D F+ K + Y + I+ D G P + K SI + D+NDN P+F V ++ P+G+ V A+D D+ + I Y + + N++ ++ S I D +KT ++ +D +++ V + +D+ + + E R+ E+ + KN + T GQN TV + I+ K + N KL + ++ ++ D G + + G LDRE + L + +D G P+ ST+ + I +LD+NDN PV + ++ IG + + D D GIN +T++L
Sbjct: 332 GNPDGTFLLKAAETK-DEYYIELNQFAHLNQQHFI-YNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPIN--MPVIRLKVSDPDLGKNALVYLEIVGGNEGDE-----FRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSI-----ANLNAVPFEIDHFSGIVKTTSLLD--FETMKRN-YELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGD--IISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAW--IEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVI---QKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYAL 916 HSP 11 Score: 80.4925 bits (197), Expect = 1.040e-14 Identity = 114/435 (26.21%), Postives = 182/435 (41.84%), Query Frame = 1
Query: 1243 VQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPA--MSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSND-NFAISIYGEI---QSKIKFDREKTDSYEFVVTARDNGEPQLNDSMV-VKVKIQDINDCTPVFEKDYFFRITESYGESIKNERL--EQIKATDKDLGQNGTVKYRLIDVKPIGI------PGNSKLKAELR------NLIKVS------FDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLND-------NAPVF----LFPS------NNMNFVNVSVEWEI------GKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEI-IIAHTMKEFSN 2391
++V D D G+N + + + + I D Y D EK S YT+ + +DQ N S K I++ D+NDN P F N K+ + ENN GS V ++ A D DS N +I YSI N N F I + I S + F+ K + YE ++ A D G P + + + + ++DIND P FE+ YG+ K+ + E + D + YRL D G G+ + +L+ ++KVS F + + +L E++ ++ F + + E L L + + VF L PS + FVN E I G+T+ ++ KD D G NG + ++ S+ + F+I P+ GE+ II + +E N
Sbjct: 422 LKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGM------LYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMKRN-YELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFER------VNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAI--SDGDYDSVFRIDPDRGELQIIGYLDRERQN 841 HSP 12 Score: 74.3294 bits (181), Expect = 7.099e-13 Identity = 144/552 (26.09%), Postives = 227/552 (41.12%), Query Frame = 1
Query: 310 FSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTT--YPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNG--RMNETSVDIAIEDCNDHPPVISIANRFG-KVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDT-----SFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSS-NNGHIVYSILNSNDN--FAISIYGEIQSKIKFDREKTDSYEFVVTAR--DNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRIT-ESYGESIKNERLEQIKATDKD 1908
FS+ + SG L V S LDRET T KL H + + V +I +N+PI + Y + V +D K + + + G++++ + +G N +F+I SK I + + K++DRE F + A D G TV V + D+NDN PE++ Y I E + G ++ ++ A D N + Y + E K F ++ L N + I A DG N V+I+I D ND+ P + N + V E+ + V+ DED NG+ NI DN + I+ T DRE IS YT+EI+ DQG+P + +INI+D NDNAP F + + EN +G + D D + N + I + N+ F + G +++ +F+ D EFV+ R DNG P L V VKI + + P+ +T S+ + + ++ A+D+D
Sbjct: 3112 FSIGKESGILKVASALDRET-------TPKYKLV----AHVQDGKDFTQECFS-----EIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKI----SKSTGI---IRLHKSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSID--IGVNADIHYFIMSGNEQGK-----FKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTF-LQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVT-----------YNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQD--EFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTP---LEVTINSFEDDFSGAFIGKVHASDQD 3616 HSP 13 Score: 71.633 bits (174), Expect = 4.571e-12 Identity = 82/333 (24.62%), Postives = 141/333 (42.34%), Query Frame = 1
Query: 1384 FDREKISVYTVEIKCVDQGNPAMSS-----MQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTD------------SYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVE--WEIGKTICTVKTKDLDQGINGTITHSLINSNKREN 2325
FDRE +Y + ++ M+S + I+++DVNDN P FVN V ++P G+ + QV+A+DLDS+ NG + Y + N GE+ K DR+ + +YE V A D + ++VK+ I+ PVFEK + Y S+K E +E A + + LI + +E ++ G+I V LD E+ISS + ++A D + + + ++D+ND +P + N+++ G I + D D G N +++ + + N + N
Sbjct: 2093 FDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGN--------GEL---FKLDRKSGELSIKQHVEGHNRNYELTVAAYDGAITPCSSEAPLQVKV--IDRSMPVFEKQF-------YTVSVK-EDVEMYSALSVSIEAESPLGRSLI----------YTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRA-TDSLSGVYAEVVLSVSIMDVND-----CYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNN 2388 HSP 14 Score: 71.2478 bits (173), Expect = 6.967e-12 Identity = 80/307 (26.06%), Postives = 139/307 (45.28%), Query Frame = 1
Query: 1384 FDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILN--SNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEP---QLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNER----LEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQ 2271
DRE + + +E+ D G+P +SS + ++++D+NDN+P F ++ V + + ++ QV A+D DS NG I YSI + + F I S G I D + + +E + A DNG P Q +V V + + P+ + + +E+ + +N++ + QI A D D N + Y + + GN N + D G I + LD E S L + D + + T ++++V+D+NDN P F + ++ VN+S E I + D D+
Sbjct: 1257 LDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSD--NEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVR----KTSENVVDLTENDKPGFLVTQILAVDDD---NDQLWYNISN-------GNDD------NTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAF---TNLLVQVIDINDNPPQF---AKDVYHVNISENIEEESVIMQLHATDRDE 1535 HSP 15 Score: 59.6918 bits (143), Expect = 2.229e-8 Identity = 88/391 (22.51%), Postives = 160/391 (40.92%), Query Frame = 1
Query: 1300 DSGKLNLKNIRFDDNFAIYKIETYPD-TSFDREKISVYTVEIKCV----DQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNG-----EPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTV-KYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREE-ISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASD 2433
D KL + +FA I T + +REK Y + +K D+ + + I ++D ND +P F + E+ P ++ +V A D D NG I YS+L ++ FAI GEI + + +E V A D G + V + ++ +N P F +T + I ++ DKD G NG + + ++D P G LKA K + ++ + +L+++ I ++ LL + D G P ++ I++ + N P+F + + V++ I + +K D D G N + ++ N+ + F+I P+ ++ +T K+ + L + A D
Sbjct: 108 DKEKLFKAEEKLVGDFAFLAIRTRTNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYG----IVRVNDKDTGINGNIGRLEIVDGNP---DGTFLLKAA---ETKDEYYIELNQFAHLNQQHFIYNLTLLAE--DLGTPRRFAYKSVPIQIKPESKNIPIF---TQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDE--FRINPDSGML--YTAKQLDAEKKSSYTLTVSAID 479 HSP 16 Score: 59.3066 bits (142), Expect = 2.943e-8 Identity = 99/421 (23.52%), Postives = 165/421 (39.19%), Query Frame = 1
Query: 1087 IYITATDG-NGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIET-----YPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDG----YPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLI 2304
+ I ATD +G E + ++I D ND P I + EN + + D D G N +++I +N ++ I+ Y T D E+I + + + D G+P++SS I + D+NDNAP FV V G V +A D D S+ + Y I+ N+ SI G I + + S ++ D +K+ + N +P+F++ Y ++ E+ + + +KA+D D G + Y ++ E++ + + G I+ DRE+ +L++ D G + SL +NDN P FL M VS E +TI TVK KD D NG++ ++
Sbjct: 2310 VSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKL--------SYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAY---ARLKISLLPENVYSPLFDQSTYEAQVPENL---LHGHNIITVKASDGDFGTYANLYYEIV-------------SEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKFGFASLKVIVVD------VNDNVPYFLLKEYKMV---VSTTVEANQTILTVKAKDDDIVDNGSVHFQIV 2694
BLAST of Protocadherin-11 X-linked vs. Ensembl Fly
Match: kug (gene:FBgn0261574 transcript:FBtr0332722) HSP 1 Score: 158.688 bits (400), Expect = 1.408e-38 Identity = 173/597 (28.98%), Postives = 281/597 (47.07%), Query Frame = 1
Query: 712 LEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXX--APEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRM--NETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDN--APRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSN-NGHIVYSILNSNDN--FAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIG-IPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIA 2463
L+II +DRE +V + D GN T S + + +T ++ N P K + E G ++ + A D D + N V+Y LS D F +N L N+ ++N ++ITA DG + +E V + ++D ND+ PV + KV E+ + +L ++ DED G N + SL + + + + R D + + + Y D E V+ + + +D G+P+++S I IIDVN+N AP F + + V EN P G+ V V A D+D+ + N I YSI + FA++ G I S + D E + Y + A+D L++ + V +++++ ND P+ +K Y+ +TE+ S++N + +KA D D+ T+ Y ++ +G +SK +IK + LDRE + L V D+G P LS+T+ I++ VLD+NDN+P F + V V + ++I V D D G NG IT+S I S K +N F+I + G I IA + + F + IKA D G K+ A
Sbjct: 829 LQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDAD--SGINAQVTYALSVECSD-------FTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQ-DEELFRIDKHTGAIRTQGY----LDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEA---SVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSK-----TGVIK-------TTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEF---DQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYS-IKSGKGKN-KFRIDSQRGHIHIAKPLDSDNEF-----EIHIKAEDNGIPKKSQTA 1386 HSP 2 Score: 149.828 bits (377), Expect = 6.426e-36 Identity = 177/621 (28.50%), Postives = 283/621 (45.57%), Query Frame = 1
Query: 661 FFQIKNPKSKQEEIYPSLE--IIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDIL-ELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNI---RIYITATDGNGRMNE--TSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI---SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKAS--DLGQNPKNNIATLYIRYI 2484
FF + K Q +I S E I K +DRE+ + + +IATD G T V + V D+NDN P K Y ++ E S G L E+ A D D + + LS + D F I L +++ ++R ++ DG E + + I + D ND+ P+ S+A V E+ + ++T V D+D G N + SL N + + I ++ S DRE IS++ + +K D G P + S+ ++NI+D+NDN P F + ++EN G+ V +V A +D N I Y I++ N+ S G++ D E + Y + A D G P L+++ V + I DIND +P F ++ +RI + + ++ L+ +KATD+D NG V Y + IG + + +N G ISV LDRE IS L +QA D G P + I I +LD NDNAP+ F S+N + V + +G T K D D+ N T ++ + E F+++ +G + T F++ +L D +I+ D G P + A + ++ I
Sbjct: 3003 FFIVSGDKQAQFQIGKSGELFIAKPLDREQLMFYNLSIIATD-GKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFD----FQSKLRFYLSGKGADD------FSIGKESGIL---KVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGE---NHDYFKISKSTGIIRLHK----SLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQN-LYRINVNEDIFVGSKILD-VKATDEDSDVNGLVTYNIERGDNIG-----QFSIDPKN-------GTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPI--FSSSNYSVV-LQENRLLGYVFLTFKISDADETPN-TTPYTFDIRSGNEGGLFRLEQDGSL---RTASRFNH--NLQDEFVIQVRVFDNGTPPLYSDAWVVVKII 3579 HSP 3 Score: 144.05 bits (362), Expect = 3.931e-34 Identity = 122/422 (28.91%), Postives = 197/422 (46.68%), Query Frame = 1
Query: 1243 VQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDN--APVFLFPSNNMNFV---NVSVEWEIGKTICTVKTKDLDQ-GINGTITHSLINSNKRENFPFKIQPEGEII-IAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIR 2478
++ KD D G NG +++D ++ R D + +I Y DRE+ + Y + I D GNP S+ + I I+DVNDN P + F + E+ IG+ V + A D DS N + Y++ +F + + G ++ DREK D+Y +TA+D G P L+ +V V + D+ND PVF ++Y F++ E + L I+A D+D+G N +++ L K + + L ++ GAI G LD E L+V A D G PSL++ +I+I ++D+N+N AP F +FV V G + V +D+D +N IT+S+ + F + +G I ++ E NF L + A D P +N +YI+
Sbjct: 794 IEAKDRDLGYNGKLVFAISDGDYDSV--FRIDPDRGELQIIGY----LDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLP---RGTVLAVIEAVDEDIGPNAEIQFSL------------KEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEF------DDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLG--IFAVNDQGSITSLSQLDAETKNFY----WLTLCAQDCAIVPLSNCVEVYIQ 1182 HSP 4 Score: 102.834 bits (255), Expect = 1.540e-21 Identity = 93/359 (25.91%), Postives = 157/359 (43.73%), Query Frame = 1
Query: 1129 TSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNG---MFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLE-----QIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPV 2172
+V + I D ND+PP S+ K+LEN + V D G N F S N+ GK + + D + + D E Y + I+ +D G P +S+ +I+I+D+NDN+P F+ + +V E+ +GS + V+A D DS NG + Y+I ++ SI G I DRE Y + A D G+PQ +S+ + + I D ND P+F + +Y ++ RL K +D D N T Y D++ GN L ++ DG++ + + V+ FD+G P L + +++++++ + P+
Sbjct: 3257 ATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGD---------LVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFS-------SSNYSVVLQENRLLGYVFLTFKISDADETPN-TTPYTF-DIRS----GNEG------GLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPI 3587 HSP 5 Score: 102.449 bits (254), Expect = 1.823e-21 Identity = 133/473 (28.12%), Postives = 190/473 (40.17%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL-NSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSF-----DGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSIGKKSHS 2535
V I + D ND+ P V EN ++ I L V D D G NG L +S N++NI FD IY TS DRE S Y ++ D G+P + +I I+D NDNAP F I+ V EN G+ + + +D D + + + F I GE+ DRE+ Y + A D + V++ ++DIND TP K R S ESI ++ L++VK I SKL+ L F G + V LDRE +L+ D + + III V D+NDN P+F S V+V + ++ I V D D G+N I +SL+ N FKI II H + L +KA D G ++IAT+ + + N NP + +S
Sbjct: 2846 VLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYL-ESDTENIQNI-FD--IDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQFQIGKSGELFIAKPLDREQLMFYNLSIIATDG---KFTAKANVEIDVKDINDNTPYCLKP---RYHISTNESI-------------------SIGTTLVEVKAIDFDFQSKLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIF---SMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDY---FKISKSTGIIRLHKSLDRETISLF--NLTVKAEDCGVPKLHSIATVAVNILD--INDNPPEFSMRQYS 3279 HSP 6 Score: 102.064 bits (253), Expect = 2.534e-21 Identity = 147/554 (26.53%), Postives = 232/554 (41.88%), Query Frame = 1
Query: 844 PEWTKDNYKVNIQE-CQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVS--QIFYINGNKLHLTNNRISGLINRNNIRIYITATDGN-GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSL--NDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYG---------ESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTT--IIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICT--VKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASD 2433
P++ KD Y VNI E + E I++L A DRD+ + + Y L T+D ++ +I I+GN + R+ +I I G G+ N + + + D NDH P + KV E+ L V+ D D G N + S+ + G + D F I + + + KI Y +++K VD GNP +SS I + ++ P+F + EN PIG+ V QV A S I ++I++ N N + I G I D E + V + +++ + I D ND P F + +Y + ES +S K+ Q+K D D+G NG V+Y ++D +N K+ S GAI + LD E + V D G P L +TTT + I V+++ND PVF N +NV++ + + V KD D N T+ +++ N E F+I+ II + +N L ++ASD
Sbjct: 1504 PQFAKDVYHVNISENIEEESVIMQLHATDRDE----DKKLFYHLH-ATQDPSSLALFRIDSISGNVI--VTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSV----FEIDPTFGIITLAG----NLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSS-----IFFNIISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNII--IHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVK--DADVGVNGMVEYHIVD-------------DLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVF-----NERELNVTLFLPTFENVFVRQVSAKDAD---NDTLRFDIVDGNTNEC--FQIEKYTGIITTRNFEILNNENDRDYALHVRASD 2010 HSP 7 Score: 102.064 bits (253), Expect = 2.975e-21 Identity = 71/263 (27.00%), Postives = 122/263 (46.39%), Query Frame = 1
Query: 1399 ISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVS-FDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP 2184
++ Y ++ D+G P S SI II+ + N P F + ++E+ P G+ + ++ + N +SI D+F IS GE+ + DRE+ +S+ +V A + P V + ++D ND P F+ ++ E + + L ++ ATD D G NG ++Y L ++N+ + + G I++ +LDRE S V A D+G+P + I+++D NDNAPVF P
Sbjct: 2726 VNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMI-----GNYTFKFSIAADQDHFMISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVIS--LVKVSATDADTGPNGDIRYYL-----------ESDTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLP 2970 HSP 8 Score: 92.8189 bits (229), Expect = 1.627e-18 Identity = 111/410 (27.07%), Postives = 181/410 (44.15%), Query Frame = 1
Query: 1111 NGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITE--SYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
N R TS+DI++ D ND+ P+ + V + + I+ V+ D D NG L K N + + D I+ + + +R Y + + D SS + +ID + P F + V E+ + S + +++ +S ++Y+I + + +F I G I + D EK S++ + A D+ + +V+ V I D+NDC P E D Y I E S+G I +I ATD D G N + Y ++ I NS+L I V+ DG + + LD E+I ++V D G PSLS+ + + I V DLNDNAP F+ PS F VSV G+ + K D D ++ + ++ N+ + +
Sbjct: 2118 NVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELK---KGNGELFKLDRKSGELSIKQHVE-GHNRN----YELTVAAYDGAITPCSSEAPLQVKVID--RSMPVFEKQFYTVSVKEDVEMYSALSV--SIEAESPLGRSLIYTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLS-GVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQIL-----KINATDNDSGANAKLSYY---IESINGQNNSELF-----YIDVT-DGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPS---YFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTY 2497 HSP 9 Score: 87.0409 bits (214), Expect = 1.086e-16 Identity = 109/440 (24.77%), Postives = 183/440 (41.59%), Query Frame = 1
Query: 1093 ITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPD-----TSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIK----ATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSF-----DGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFL-------FPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI 2340
I+ TDG T++ + + D ND+PP + + EN +++ ++ + D D+ + + +L + + A+++I++ D EK + + + + DQG P + K +N+ D ND+ P F KI V E+ IGS + +VRA+D DS +N I YSI+ N I +G I + K Y V A D G P L+ + V + + + P F + +I E E + T + ++ + +I GN I SF G I + GN+D E I L V+ + + S+ III +LD NDN P F+ P + V + K T++ KD D G+NG + + +++ + +NF FKI
Sbjct: 1479 ISVTDGTFTAF-TNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFY----------HLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTN-----------NIAIEIFENLPIGTFVTQVTARSSSSIFFNIIS-------GN----------INESFRINPSTGVIVINGNIDYESIKVFNLTVKGTN--MAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVD-DLAKNF-FKI 1875 HSP 10 Score: 81.2629 bits (199), Expect = 6.488e-15 Identity = 139/609 (22.82%), Postives = 256/609 (42.04%), Query Frame = 1
Query: 646 GNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNT-KNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATD----GNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFD-DNFA-IYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQ-KFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQS-KIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKI--QDINDCTPVF---------EKDYFFRITESYGESIKN-------ERLEQIKATDKDLGQN----------------------GTVKYRLIDVKPIGIPGNSKL-----KAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSL 2301
GN F +K ++K +E Y L +++++ F+ + L+A D G + +V + + + N P +T++ Y+V+I E + +I DP+ KN LV ++ E + F IN + L + +++ + ++A D G+ + + V I+++D ND+ P+ N+ + EN + + KD D G N S+ NL + F+ D+F+ I K + D F+ K + Y + I+ D G P + K SI + D+NDN P+F V ++ P+G+ V A+D D+ + I Y + + N++ ++ S I D +KT ++ +D +++ V + +D+ + + E R+ E+ + KN + T GQN TV + I+ K + N KL + ++ ++ D G + + G LDRE + L + +D G P+ ST+ + I +LD+NDN PV + ++ IG + + D D GIN +T++L
Sbjct: 332 GNPDGTFLLKAAETK-DEYYIELNQFAHLNQQHFI-YNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPIN--MPVIRLKVSDPDLGKNALVYLEIVGGNEGDE-----FRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSI-----ANLNAVPFEIDHFSGIVKTTSLLD--FETMKRN-YELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGD--IISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAW--IEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVI---QKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYAL 916 HSP 11 Score: 80.1073 bits (196), Expect = 1.161e-14 Identity = 114/435 (26.21%), Postives = 182/435 (41.84%), Query Frame = 1
Query: 1243 VQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPA--MSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSND-NFAISIYGEI---QSKIKFDREKTDSYEFVVTARDNGEPQLNDSMV-VKVKIQDINDCTPVFEKDYFFRITESYGESIKNERL--EQIKATDKDLGQNGTVKYRLIDVKPIGI------PGNSKLKAELR------NLIKVS------FDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLND-------NAPVF----LFPS------NNMNFVNVSVEWEI------GKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEI-IIAHTMKEFSN 2391
++V D D G+N + + + + I D Y D EK S YT+ + +DQ N S K I++ D+NDN P F N K+ + ENN GS V ++ A D DS N +I YSI N N F I + I S + F+ K + YE ++ A D G P + + + + ++DIND P FE+ YG+ K+ + E + D + YRL D G G+ + +L+ ++KVS F + + +L E++ ++ F + + E L L + + VF L PS + FVN E I G+T+ ++ KD D G NG + ++ S+ + F+I P+ GE+ II + +E N
Sbjct: 422 LKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGM------LYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMKRN-YELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFER------VNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAI--SDGDYDSVFRIDPDRGELQIIGYLDRERQN 841 HSP 12 Score: 74.3294 bits (181), Expect = 6.981e-13 Identity = 144/552 (26.09%), Postives = 227/552 (41.12%), Query Frame = 1
Query: 310 FSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTT--YPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNG--RMNETSVDIAIEDCNDHPPVISIANRFG-KVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDT-----SFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSS-NNGHIVYSILNSNDN--FAISIYGEIQSKIKFDREKTDSYEFVVTAR--DNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRIT-ESYGESIKNERLEQIKATDKD 1908
FS+ + SG L V S LDRET T KL H + + V +I +N+PI + Y + V +D K + + + G++++ + +G N +F+I SK I + + K++DRE F + A D G TV V + D+NDN PE++ Y I E + G ++ ++ A D N + Y + E K F ++ L N + I A DG N V+I+I D ND+ P + N + V E+ + V+ DED NG+ NI DN + I+ T DRE IS YT+EI+ DQG+P + +INI+D NDNAP F + + EN +G + D D + N + I + N+ F + G +++ +F+ D EFV+ R DNG P L V VKI + + P+ +T S+ + + ++ A+D+D
Sbjct: 3112 FSIGKESGILKVASALDRET-------TPKYKLV----AHVQDGKDFTQECFS-----EIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKI----SKSTGI---IRLHKSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDI--GVNADIHYFIMSGNEQGK-----FKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTF-LQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVT-----------YNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQD--EFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTP---LEVTINSFEDDFSGAFIGKVHASDQD 3616 HSP 13 Score: 71.633 bits (174), Expect = 4.421e-12 Identity = 82/333 (24.62%), Postives = 141/333 (42.34%), Query Frame = 1
Query: 1384 FDREKISVYTVEIKCVDQGNPAMSS-----MQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTD------------SYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVE--WEIGKTICTVKTKDLDQGINGTITHSLINSNKREN 2325
FDRE +Y + ++ M+S + I+++DVNDN P FVN V ++P G+ + QV+A+DLDS+ NG + Y + N GE+ K DR+ + +YE V A D + ++VK+ I+ PVFEK + Y S+K E +E A + + LI + +E ++ G+I V LD E+ISS + ++A D + + + ++D+ND +P + N+++ G I + D D G N +++ + + N + N
Sbjct: 2093 FDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGN--------GEL---FKLDRKSGELSIKQHVEGHNRNYELTVAAYDGAITPCSSEAPLQVKV--IDRSMPVFEKQF-------YTVSVK-EDVEMYSALSVSIEAESPLGRSLI----------YTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRA-TDSLSGVYAEVVLSVSIMDVND-----CYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNN 2388 HSP 14 Score: 70.8626 bits (172), Expect = 7.517e-12 Identity = 80/307 (26.06%), Postives = 139/307 (45.28%), Query Frame = 1
Query: 1384 FDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILN--SNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEP---QLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNER----LEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQ 2271
DRE + + +E+ D G+P +SS + ++++D+NDN+P F ++ V + + ++ QV A+D DS NG I YSI + + F I S G I D + + +E + A DNG P Q +V V + + P+ + + +E+ + +N++ + QI A D D N + Y + + GN N + D G I + LD E S L + D + + T ++++V+D+NDN P F + ++ VN+S E I + D D+
Sbjct: 1257 LDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSD--NEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVR----KTSENVVDLTENDKPGFLVTQILAVDDD---NDQLWYNISN-------GNDD------NTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAF---TNLLVQVIDINDNPPQF---AKDVYHVNISENIEEESVIMQLHATDRDE 1535 HSP 15 Score: 59.6918 bits (143), Expect = 2.155e-8 Identity = 88/391 (22.51%), Postives = 160/391 (40.92%), Query Frame = 1
Query: 1300 DSGKLNLKNIRFDDNFAIYKIETYPD-TSFDREKISVYTVEIKCV----DQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNG-----EPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTV-KYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREE-ISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASD 2433
D KL + +FA I T + +REK Y + +K D+ + + I ++D ND +P F + E+ P ++ +V A D D NG I YS+L ++ FAI GEI + + +E V A D G + V + ++ +N P F +T + I ++ DKD G NG + + ++D P G LKA K + ++ + +L+++ I ++ LL + D G P ++ I++ + N P+F + + V++ I + +K D D G N + ++ N+ + F+I P+ ++ +T K+ + L + A D
Sbjct: 108 DKEKLFKAEEKLVGDFAFLAIRTRTNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYG----IVRVNDKDTGINGNIGRLEIVDGNP---DGTFLLKAA---ETKDEYYIELNQFAHLNQQHFIYNLTLLAE--DLGTPRRFAYKSVPIQIKPESKNIPIF---TQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDE--FRINPDSGML--YTAKQLDAEKKSSYTLTVSAID 479 HSP 16 Score: 59.3066 bits (142), Expect = 3.070e-8 Identity = 99/421 (23.52%), Postives = 165/421 (39.19%), Query Frame = 1
Query: 1087 IYITATDG-NGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIET-----YPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDG----YPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLI 2304
+ I ATD +G E + ++I D ND P I + EN + + D D G N +++I +N ++ I+ Y T D E+I + + + D G+P++SS I + D+NDNAP FV V G V +A D D S+ + Y I+ N+ SI G I + + S ++ D +K+ + N +P+F++ Y ++ E+ + + +KA+D D G + Y ++ E++ + + G I+ DRE+ +L++ D G + SL +NDN P FL M VS E +TI TVK KD D NG++ ++
Sbjct: 2310 VSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKL--------SYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAY---ARLKISLLPENVYSPLFDQSTYEAQVPENL---LHGHNIITVKASDGDFGTYANLYYEIV-------------SEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKFGFASLKVIVVD------VNDNVPYFLLKEYKMV---VSTTVEANQTILTVKAKDDDIVDNGSVHFQIV 2694
BLAST of Protocadherin-11 X-linked vs. Ensembl Fly
Match: ft (gene:FBgn0001075 transcript:FBtr0077478) HSP 1 Score: 155.221 bits (391), Expect = 1.708e-37 Identity = 202/752 (26.86%), Postives = 332/752 (44.15%), Query Frame = 1
Query: 232 NVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG---NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRM--NETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN-FAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWE-IGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMK-EFSNFRSLPD---RLIIKASDLGQNP 2448
N Y NS +K + D F +N +SGD+ + LDRE E T +M T + +E+ DINDN PVF+ ++EN+P GT P A DKD +G++ + + +G + F I S+ EI +DREE + L+A D + S +T+ V+DVNDN P++ Y V + E S+G+ + A D DD +N +V Y +S R + ++ + KL L S + I I+A D + ++ + + + P +AN + E+ + ++T V KG G ++ +G + ++R D N + + D E +Y + I+ D P++ S+ ++N+ D NDNAP I V+E + V+A D DS +NG+++Y + N D F I+ GEI ++++ DRE+ Y FVV A D G P + + V + + D ND P F + + +TE+ + + ++ ++D DLG N Y + PG K + E ++ G I+V G+LDRE+ L V A D + T I I + D NDNAP F + +F + +G+ I T + K QG N I++SL ++ + F I P GE+ ++ + S + P+ L + A+D G+ P
Sbjct: 2409 NAYDADTPPLNSQVRYFLKEGDSD-LFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKD--------------EGLNAKLRFNLLGEHMHRFHID---SETGEI----STATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDD--GENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKSH--DDLTYTIVISAMDQGEQSLSSKAELTVILRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAI--AGGIMGDSLRVDPNSGLLSVG---QDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGTFEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRLFSLNVTEN---AEIGSFVIRVTSSDLDLGANANASYSFSEN-----PGE-KFRIEPQS-------GNITVAGHLDREQQDEYILKVVASDGAW---RAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDK---QGPNSVISYSL----QQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPP 3103 HSP 2 Score: 147.517 bits (371), Expect = 3.294e-35 Identity = 200/737 (27.14%), Postives = 318/737 (43.15%), Query Frame = 1
Query: 169 VITLNVEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYING----NKLHLTNNRISGLINRNNIRIYITATD-GNGRMN-ETSVDIAIEDCNDHPPVISI-----ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAIS---IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQI-KATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPS-LSTTTTIIIEVLDLNDNAPVFLFP-------SNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSL 2301
+ + +F V E G VG + +K P S + NE F+L+ +G++ LDRE + ++ + + Q T+ I++ I++ D+NDN P F I+ E+ GT L A D D + GV Y +D N F+ NP Y LE N+DRE S+ + A D G+ + G V V + DVNDN P + +Y V++ E G ++ ++A+D D + N ++Y L++ + + I+ N TN + S ++ + + A D G+ R + T V + + D NDH P+IS + V EN ++ V VKD D G NG + +L + + I ++ + DRE+I Y + + +DQG PA ++ I++ DVND+ P F + E P GS V + A D D+ N + Y IL+ N+ S + G I + DRE D+ E ++ARD G +KV I D ND P F + + GE + + + ATD D G NG+V + L P L A G ++ LDRE++S ++ V A D G P+ S T T+ + V D+NDN P F +P +++ + + + E E + + V D D G N I + L
Sbjct: 64 AVDTSADFEVLEGQPRGTTVGFIPTK----PKFS----YRFNEPPREFTLDPVTGEVKTNVVLDREGM----RDHYDLVVLSSQPTYPIEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVD---------NKFRLVTTANPSGDTS--YLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGD--NSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNVKSSA--SQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRV----NGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQR---EQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDA---------LTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQF-YPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRL 756 HSP 3 Score: 144.821 bits (364), Expect = 2.521e-34 Identity = 138/513 (26.90%), Postives = 221/513 (43.08%), Query Frame = 1
Query: 1072 RNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRN-----GMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL--NSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNG------------------------------------EPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPD-RLIIKASDLG-QNPKNNIATLYI 2475
++ + I +DG + E I + D ND+PP+ + EN ++ + + +D D G+N G+ ND LN + + + D E++ Y + ++ D G P++S+ N++D+NDNAP F V EN PI + V V A D+DS NNG I YSI + + F I G I+++ DRE +Y VTARD + +L+ ++ V + I+D+ND PVF I E+ N + +KA D D G+NG + Y + + + + + L L DG + V LDRE SS L + A D G P ST + ++I +LD NDN+PVF +V+ IG + V D+D+G NG I +S++ ++ +F + G + +A + N+ L L ++A D +NP + A L I
Sbjct: 1888 KSKYELRIRVSDGV-QYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNPQT-------GMLTLTA----RLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAIMENVA---INTVVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLN-----PTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVF---DPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNHDFSIS-EDTGVVRVAKNL----NYERLSRYSLTVRAEDCALENPAGDTAELTI 2372 HSP 4 Score: 143.28 bits (360), Expect = 7.653e-34 Identity = 122/420 (29.05%), Postives = 179/420 (42.62%), Query Frame = 1
Query: 1147 IEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY-GEIQSKIKFDREK---------------------TDSYEFV-VTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDG--YPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
I D NDH PV + + E K + D D G NG + + + + F D + + DRE+ Y + + C D G P+ SS+ I++ID NDNAP+F N F + EN P + VG++ A+D D N + +++ + +F I G I++ FDRE +Y + T DNG P+L D + VKV + D+ND P F Y I+E E + + D D G NG V Y L GN + L S G +S+ LDRE L+V A D +P LS+ +I I VLD NDNAP F S+ ++ + S G + + D DQG+N + S+ N+R+ F
Sbjct: 1039 IADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGV-FPDGYLFVR------APLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGT---HITHVFTQDADEGLNGDVYYSLAK-------GNEAGQFNLD-----SATGQLSLGRRLDRESQEIHHLIVVAKDAALKHP-LSSNASITIVVLDENDNAPEFTQSSSEVSVLETS---PTGTELMRFRASDADQGVNSQVVFSISAGNRRDTF 1432 HSP 5 Score: 139.043 bits (349), Expect = 1.563e-32 Identity = 168/634 (26.50%), Postives = 282/634 (44.48%), Query Frame = 1
Query: 730 IDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXX--APEWTKDNYKVNIQE-CQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNK-------LHLTNN--------RISGLINRNNIRIYITATD-GNGRM-NETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSL---NDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQG-NPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN--DNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPS---LSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGK----TICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSIGKKS 2529
+DREE + + D G + S V V++ +++N AP++T + +I E ++ + +L A DRD +N +S+ LS +T+D I ++ +I + + ++ N + G + N + + T +D G R+ ++ V + + D ND+ P A + E + +T V +D D+G NG SL N++G+ NL + + DRE ++ + + D +SS +I ++D NDNAP F V+E +P G+ + + RA D D N +V+SI N D F I SI G + D E SY +TA D G P L+ +++ V + D ND P+F R + G +K + + A D D G NG V Y + +P +P + R+ + G I +DRE I + +L V A D PS LST + + V D+NDNAPVF+ +MN + ++ K + V KD D NG +T+ +++ + FK+Q II +F + + +L +K++D + + +YI T + P S G +S
Sbjct: 1111 LDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRD--IGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSLG---------RRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKE-GIPLKTP-IVTVTADDPDSGLNGKVSYAISKQEP-QLP-------QGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFV----SMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQEL---FKLQRNTGIITFTPGPQFK--QEVRYQLTLKSTDEAVQSERRSSEVYI------TIITPGSGGSES 1708 HSP 6 Score: 137.117 bits (344), Expect = 6.112e-32 Identity = 131/433 (30.25%), Postives = 192/433 (44.34%), Query Frame = 1
Query: 1117 RMNET-SVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNG-----MFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL--NSNDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNG-EPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTM 2376
R++ T V I I+D ND PV AN ++EN ++ V+ D D+GRNG M E D G+ + + ++ + DRE S Y + I D+G P S+ + I I+D NDN+P F K V EN IG+ V QV A D+D NG I YSI+ + N +F+IS G ++ + E+ Y V A D E D+ + + I DIND P F + Y R+ E+ + G TV D P+ LK +L ++ + G I++ LDRE+ S L + A D G P L+ T + +EV D+NDN PVF S + V G + T + D D+G+N + +L+ + F I E GEI A T+
Sbjct: 2146 RLSSTVKVTILIKDVNDEVPVFISANETA-IMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVD----ALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMEN--------------TVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYH---ATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMHR---FHIDSETGEISTATTL 2553 HSP 7 Score: 129.413 bits (324), Expect = 1.244e-29 Identity = 169/645 (26.20%), Postives = 287/645 (44.50%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXX-----APEWTKDNYKVNIQE-CQSEGD---ILELIANDRDDPNTKNGLVSYQLSDRTED----RKIVSQIFYINGNK--------LHLTNNRISGLINRNNIRIYITA-TDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQK--QKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREK-ISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN-FAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVF-LFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
F +T V I+E IP+ T A D DS G +Y I++ QE Q+ G +F N ++ + ++ IDRE +F ++ATD + T + V AP + N + + S+G ++++ A D D ++ NGLV+Y++ ++ ++ I + G + L L + + R + +YIT T G+G +E+SV P + G V EN+ I+ T + + F ++ +G + FD + + + T + DRE Y VE+ + G +S K + ++D ND+ P+F++ +++V E+ IG T+ +RA D D+ G + + +++ +D F + G++ DRE YE + D Q ++ +++ D ND P+FE Y F I E+ + + ++ QI A D DLGQN + Y ++ S ++ +L + G +++ LD EE+ L+VQA D+G PSLSTT T+ VLDLNDNAP+F ++ F NV + E + TV KD+D G NG I +S+ + F
Sbjct: 1489 FPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISK-----QEPQLPQ-GRHFGI----NTETG------VIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDAD--SSSNGLVTYEIVSGPQELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGG-SESSV----------PQFEQRSKLSGSVYENEPIGTSILTVTAHLASAEIE---YFVTNVTATGSRGQVDRLFDIDAKLGILSTAAE--LDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTL--GSVTFLLMDGHDGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSDG--VQYTEAYAT-IQVSDTNDNPPLFEDTVYSFDIPEN---AQRGYQVGQIVARDADLGQNAQLSYGVV----------SDWANDVFSLNPQT--GMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATE----VVTVSAKDIDSGNNGLIEYSITAGDVDSEF 2075 HSP 8 Score: 125.561 bits (314), Expect = 1.946e-28 Identity = 162/595 (27.23%), Postives = 264/595 (44.37%), Query Frame = 1
Query: 754 FVFILIATDFGNQT--GSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKN---GLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY----GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYF-FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTT----IIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLD-QGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM--KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYI 2475
+ ++ATD G C V + + D ++N P++ + Y + + G I+ + AND+ D T L+++ LS IF + + +T + + + + ATD + +ET V I + N P S+ + V EN+ + TV D+D G NGM S+ SG ++ D+ I+ D + I Y + I D G +SS+ +I + DVNDN P F +K ++ EN P+G+ V Q A D DS N I Y+ L S + I G I S + FD E+ Y + A+ N + + + V + +N+ P F + F F ++E+ S R+ ++ATDKD G++G V Y L+ G+S K ++ + G I V +LDRE + + L V A + Y S+ T +II + D ND P F+ + +S +G + TVK D D + N ++S+IN N +++F +Q GEI A + +E S + L+I A D G P+ AT++I
Sbjct: 3090 YALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDYSLMTFNLS----------SIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSI--SGGNERQDFSVDERTGGIVIQQ----QLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAK-NPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSET---SAVGTRVGAVQATDKDSGEDGRVYYLLV--------GSSNDKG-----FRIDTNTGLIYVARHLDRETQNRVVLTVMAKN--YGSIRGNDTDEAQVIISIQDGND-PPEFI---KHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQ-TGEISTASRLDREETSTY-----NLVIGAIDTGLPPQTGSATVHI 3639 HSP 9 Score: 112.464 bits (280), Expect = 1.648e-24 Identity = 118/422 (27.96%), Postives = 189/422 (44.79%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVL---ENQK--QKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIET--YPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY--GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYF-FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRL--------IDVKPIGIPGNSKLKA----ELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAF--DDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
V+IAI D ND+ PV ++ + EN Q+I L+ +V+D D G N SL ++ + F I + Y E S+ VE+ D G+P +SS S+ I DVND+ P F + + E + + + A D+D +NG I Y I+ N ++ G + + DRE+ D Y V+ RD G+P + + V + + D ND P F F F I E+ + + + ++ A D+D+G+N + + L ID + N +K + L+KVS + S R ++ +L++A D+G P L + + V D+NDNAP FL + V +S G I V T+D D+G+NG + +SL N+ F
Sbjct: 928 VNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLS--RVRDRDAGVNSRISYSLTNNP---------NQQFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGVFPDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPEN---APADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTR------NGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYH---VTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQF 1326 HSP 10 Score: 109.768 bits (273), Expect = 1.131e-23 Identity = 115/433 (26.56%), Postives = 181/433 (41.80%), Query Frame = 1
Query: 1069 NRNNIRIYITATDGNG--RMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDT---SFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAP-----RFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSND--NFAISIYGE---IQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGY-PSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKR 2319
+R + ++ I+A DG R V++ I D ND+PP+ ++ + E + TV D D G N L ++ N ++ T S +K V+TV + D G+P ++N++D ND+ P F + K+ V EN G+ V V D DS NG I++ N+ +F + + ++ DRE+ Y V A D G P + + + + D+ND PVFEK + + + + I ATD+D G N V Y ++ GN EL+ G I G LDRE +++L + A D G P + T +I +LD ND AP F S V + + + + D DQG NG++T +L S +R
Sbjct: 232 SRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFAR--DHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPT--GSFVASITATDEDTGVNAQVHYDILS-------GN-----ELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVI-ILDENDEAPQF---SQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVER 644 HSP 11 Score: 98.9821 bits (245), Expect = 2.605e-20 Identity = 158/640 (24.69%), Postives = 269/640 (42.03%), Query Frame = 1
Query: 619 DQENQVKTIGNNFQ-FFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYI---TATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDK-GRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY---GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRIT---ESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNF-VNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSL 2493
D N + + N+F F+I ++ EIY + + DREE + F++ A D G + TG+ +V + + D NDN P++T+ + +N+ E G ++ + ++D D N SY S+ ++ F I ++T ++G ++R YI A+DG R ET + I I+D ND+ P + E Q+ ++ + D DK G N + SL + + + F+ K + + + R ++Y + + D G P + S +INI+D ++N P+F + + ++ G + +V A D + YS++ N + S+ G I YE VV A D G P +D V + + N TP F + + I E G +I + ATD D G NG ++Y + GN E ++ G I + LD + I L + D GY LS+ + I + D+NDN PVF N+ + + +G + D D N I ++ + S +F Q G I A + ++ R L IKA +NP +++ + Y+H L
Sbjct: 2841 DNGNVIYRLQNDFDGTFEI----TESGEIYTRMRL----DREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTR-LFSLNVTENAEIGSFVIRVTSSDLD--LGANANASYSFSENPGEK------FRIEPQSGNIT---VAGHLDREQQDEYILKVVASDGAWRA-ETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPSPMFSIDPATGEVFS-KKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDYSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILT-----VGATDDDTGPNGMLRYSISG-------GN-----ERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVF----NHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSF-DYEERRIY--TLQIKA----KNPDSSMESYANLYVHVL 3430 HSP 12 Score: 97.0561 bits (240), Expect = 9.965e-20 Identity = 125/458 (27.29%), Postives = 193/458 (42.14%), Query Frame = 1
Query: 844 PEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLI--NRNNIRIY---ITATDGNGRMNE-TSVDIAIEDCND-HPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKIS--VYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLD-SSNNGHIVYSILNSN--DNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDY---FFRITESYGESIKNERLEQIKATDKDLGQNG-TVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDN 2163
P + Y I E + G + + A D+D P KN ++ Y DR F+I ++ +N IS + + RIY I A + + M ++ + + N+ +P + F V E + VQ D+D G +G L G N K R D N + + + DRE + V TV K + + I+I D ND P F+ + E P+G+ V V+A+D D + N YSI+N N +F I + GEI + + DRE+T +Y V+ A D G P S V ++++D+ND P F + + E G SI + A+D DL +NG Y+LI K S L + RN G + + DRE ++ +++ D G P + + I VLD NDN
Sbjct: 3332 PVFNHKEYHCYIPENKPVGTFVFQAHAADKDSP--KNAIIHYAFLPSGPDRH-----FFI----MNQSNGTISSAVSFDYEERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPVFHF-DVSETSAVGTRVGAVQATDKDSGEDGRVYYLL--VGSSNDKGFRIDTNTGLIYVARH----LDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMT-----LIASDPDLPRNGGPFTYQLIGGK-----HKSWLSVD-RN------SGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDN 3753 HSP 13 Score: 86.2705 bits (212), Expect = 1.893e-16 Identity = 142/573 (24.78%), Postives = 240/573 (41.88%), Query Frame = 1
Query: 271 RSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQE----NQV-KTIGNNFQF-----------FQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATD-GNGRMNET---SVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDED-KGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLD-SSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDL 1911
R S+ NE+ FS++ +G ++++ LD + I E L + + I + D+NDN PVF + I EN P+GT A DKDS K + +Y G D+ NQ TI + F + KNP S S+E N+ +V +L +F P++ + + ++ E + G + + A D+D + ++G V Y L + D+ F I+ N + R +N + + + A + G+ R N+T V I+I+D ND PP + E +TTV+ D+D + +N F S+ + NLK F + +I T + DRE+ S Y + I +D G P + I + DVNDN P F + ++ EN P G+++ + A D D N G Y ++ +S+ G ++S FDRE T E ++ D+G+P+ ++ + + D ND P + ++ G+ N +L ++ D D+
Sbjct: 3265 RYSISGGNERQD-FSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAI-IHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNPDS-------SMESYANL-------YVHVLGVNEF-------------------YPQFLQPVFHFDVSETSAVGTRVGAVQATDKD--SGEDGRVYYLLVGSSNDKG-----FRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIING---NLKQ-SFKIDVQTGEISTA--SRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKHKSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQND-NPSTTRSLHIAVSLFNGDLPSNVKLADVRPNDIDI 3787 HSP 14 Score: 80.8777 bits (198), Expect = 6.756e-15 Identity = 77/310 (24.84%), Postives = 131/310 (42.26%), Query Frame = 1
Query: 1474 INIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNG-----HIV-------YSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQ---------LLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPV--FLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
I ++DVNDN+P F E+ G+ + A D D NG IV + ++ + + + Y +++ DRE SY+ ++ARD G P + V V I D+ND P+F+ DY + E+ ++ + + A+D DLG N + Y L AE + V+ + G IS ++ + ++++ V A D G P T + + +LD ND+ P+ F F + V G + V KD D G+NG + +++ N+ +F
Sbjct: 144 IKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNET---ALPGTPVVTVMASDNDLGDNSKITYYL---------------AETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHF 435
BLAST of Protocadherin-11 X-linked vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0078045) HSP 1 Score: 153.68 bits (387), Expect = 3.919e-37 Identity = 133/454 (29.30%), Postives = 201/454 (44.27%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAI--EDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKN-IRFDD---NFAIYKIE--TYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVF 2175
APE+ ++++ E G L A+ D + +G V+Y L + +F I+ HL ++ + + +TATDG T++ I + +D ND+PPV V E++ + V D D G N + D+G N+ N I D +F I+ Y DRE Y + + D G PA + + + ++D NDN P+F F + EN GS VG V A DLD N I YS+L N +F + + GEI ++ DRE + Y+ VV ARD G P + + V++ + D+ND P D + E + +++A D+D GQN ++ Y ++ G L ++ S G I LD EE S +L V A D G P T + +EVLDLNDN P F
Sbjct: 928 APEFEASMVRISVPESAELGAPL-YAAHAHDKDSGSSGQVTYSLVKESG-----KGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEI-ADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVK-------GRDSDGHGLFSIDPTS--GVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTF 1365 HSP 2 Score: 151.754 bits (382), Expect = 1.539e-36 Identity = 185/664 (27.86%), Postives = 285/664 (42.92%), Query Frame = 1
Query: 502 INIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQE---CQSEGDILELIANDRDDPNTKN-GLVSYQLSDRTE------DRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDG-NGRMN-ETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDD-NFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--FAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQP-EGEIIIAHTMKEFSNFRSLPDRLIIKASDLG 2439
+++ EN P+G A D D + Y TIG F+ +S EI I +D E S+ F ++ATD G + + + + +TDVNDN P + YKV+++E S+ ++A DP+ N G VSY++ E DR +IF + + L + + L I+ATDG N R N + V ++I D PP+ A V E+ + ++ +V D S+ +I + N I K D E S + I+ G P + + +I + DVNDNAP F + V E+ +G+ + A D DS ++G + YS++ + FAI G + D E + + +VTA D G P L+ ++ + V +QD+ND PVFEKD Y ++ES SI N ++ Q+ A+D D G N + YR++D + + ++ G I + LDRE QL V A D+G P+ T +I+ VLD NDN P F + F + G + V DLD G N I +SL+ N F++ P GEI + R L D L+++A D G
Sbjct: 618 VSVAENEPVGRCILKVSASDPDCGVNAMVNY---------------TIGEGFKHLTEFEVRSASGEIC----IAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRS-TGEIFVVRPDMLSVRTQPMHML--------NISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAK-------PLDHEAKSQVLLNIQAT-LGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSES--RSI-NAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPK--FQKSKYEF-RIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSS----FQVHPVTGEISTREPLDR--ELRELYD-LVVEARDQG 1232 HSP 3 Score: 150.214 bits (378), Expect = 5.454e-36 Identity = 187/691 (27.06%), Postives = 300/691 (43.42%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQT--GSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETS--VDIAIEDCNDHPPVISIA----NRFGKVLENQKQKIILTTVQVKDED-KGRNGMFECSLND-SGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY-----GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKT---ICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLI-IKASDLGQNPKNNIATLYIRYIHSL 2493
F T I EN P L A+D D Y + Y I GN F++ + + + +Y L+I +DRE + ++ A D G G TV + + DVNDN P + + Y + E + G +L++ A+D D +NGLV Y ++ R D++ Q+F I+ + N+ + + + A D + ET+ V I + D ND+ P I++ + K+ E+ + + + V D D K +LN G L DN I P DRE +S YT+ + D+G P + + + + I DVNDN P F + +V+E G++V QV A D D N + YS+ + + A G I ++ D E + V ARD G P L+ + V V I D+ND P+F++ F+ ++ + E + L ++ A+D D G N V Y IG + E+R S G I + G LD E SS + V A D G LSTT I +++ D+NDN PVF +P + S + + I V D D G G +++ ++ N+ F + GEI + + + R+ P ++ I A+D G N A +++ I ++
Sbjct: 174 FPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVS-------------GNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTD--ADENGLVEYAINRRQSDKE---QMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTT---RDNSIYLVIVHLP---LDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQS-FYNVSVAENEPVGRCIL-KVSASDPDCGVNAMVNY------TIGEGFKHLTEFEVR-----SASGEICIAGELDFERRSSYEFPVLATDRG--GLSTTAMIKMQLTDVNDNRPVF-YPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRID-RSTGEIFVVR--PDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAM 821 HSP 4 Score: 118.627 bits (296), Expect = 2.557e-26 Identity = 195/794 (24.56%), Postives = 339/794 (42.70%), Query Frame = 1
Query: 277 SLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPS---LEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXX--XXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGN-KLHLTNNRISGL--INRNNIRIY---ITATDGNG--RMNETSVDIAIEDCNDHPPVISIANR-FGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDT-----SFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQV----RAMDL------DSSNNGHIVYSILNSNDNFAISIY------GEIQSKIKFDREKTDSYEFVVTARD---NGEPQLNDSMVVKVKIQDINDCTPVFEKDYF-FRITES--YGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDG---YPSLSTTTTIIIEVLDLNDNAPVFLFPSNN---MNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDR--LIIKASDLGQNPKNNIATLYIRYIHSLTNLNP 2508
SL+K + K F+++ SG LI+ LD E+ +T + + + + I++++ D+NDN PVF+ + +N+ E+ I A D D+ TY I G+D + + Q F I +P+ + + +DRE + ++ATD G V+V D NDN P++ K Y+ I+E G ++ G+V+ D E+ I + IN + ++H IS ++R +Y + A D R V I + D ND+ P I+ V E Q + V+ D D G+N S+ R D ++ I+ D E+ S+Y + + D GNP +++ + ++D+NDN P F + +F V E+ +G VG + R D+ +S + + Y++ + + + G + DRE + + A D + PQ + ++ VK+++ D+ND P + +D +++E+ G I N ATD D G NG ++YRLI P ++ + + +L ++ S GA+S+ LD E + L+VQA D L T+ T+ + +LD ND+AP F+ P+++ + +S IG+ + + D D G NG +T+ + N F Q G I + ++ + R LII A D GQ P+ ++L + I ++ NP
Sbjct: 969 SLVKESGK-GLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDA-GVDNVTNSISSSDVSQHFGI----------FPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVV--------------GVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKG--------RDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQ-SSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHN-----FTATDADTGTNGDLQYRLIRY----FPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQ-TGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQ-PEPKKSSLNLHLIVQGSHNNP 1716 HSP 5 Score: 115.161 bits (287), Expect = 2.872e-25 Identity = 119/427 (27.87%), Postives = 193/427 (45.20%), Query Frame = 1
Query: 916 IANDRDDPNTKNGLVSYQLS-DRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNP-AMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSND-NFAIS-IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMV-VKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLF 2181
+AND + + G+++ + DR V ++ + N+ + S + + I T + ++ I + D ND+ P + +G + + ++ TV D D+G N S+ NL N +F + + ++ P DRE+ S YT++I+ D+G P + +I + D NDNAPRF V E+ P+G++V Q+ A+D D N +VYS+ N FAI G I + K DRE SY F+V A D G ++ + V V++ + DIND P+FE+ + I + + L +++A D DLG N + Y L NS + A+ R I S GA+S +L E + L V A D G P S+ I + + + PV F
Sbjct: 1762 VANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANR---QSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHTVVASDLDEGPNADLIYSITGG---NLGN-KFSIDSSSGELSARP---LDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFER--YPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSL-------NAENSAVSAKFR--INPS-TGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRF 2166 HSP 6 Score: 99.3673 bits (246), Expect = 1.940e-20 Identity = 143/557 (25.67%), Postives = 218/557 (39.14%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQL----SDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNE-----TSVDIAIEDCNDHPP---------------VISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSL---NDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDV----NDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILN--SNDNFAISIY-GEIQSKIKFDREKTDSYEFVVTARD-NGEPQLNDSMVVK----------------------VKIQDINDCTPVFEKDYFFRITESYGESIKNER----LEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD---GAISVYGNLDREEISSIQLLVQAFDDGYP-SLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNK 2316
APEW +D + + E G I+ D T NG + Y+L E ++ +F ++ L+ + + A D + + E +V + I D NDH P IS A R G+V+ + + DED G NG + N G+ + + I +++ P + D EK + + I D G P +K S+N+ + ++N PRF+ + ++EN P GS V QV A L + N ++ Y I +ND F + G I ++ +FDRE SY V RD N + L+ S V K + + D+ND +P FR YG S+ + + A+D D G N + Y + G GN K S D G +S LDRE+ S L +QA D G P S I I V D NDNAP F +V + +G ++ + D D G+N + +SL N +
Sbjct: 1482 APEWPQDPIDLQVSEATPVGTIIHNFTATDADTGT-NGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAH---------IVAVDEDSGDNGQLTYEITGGNGEGRFRINS----QTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQP---EPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPE------FRPGSCYGLSVPENSEPGVIHTVVASDLDEGPNADLIYSITG----GNLGN-----------KFSIDSSSGELSAR-PLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTG---SVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQ 1996 HSP 7 Score: 98.2117 bits (243), Expect = 3.718e-20 Identity = 105/356 (29.49%), Postives = 153/356 (42.98%), Query Frame = 1
Query: 1432 DQGNPAMSSMQKFSINIIDVNDNAPRF-VNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN--DNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMV-VKVKIQDINDCTPVFEKDYFFRITESYGESIK-NERLEQIKATDKDLGQNGTVKYRLIDVKP--IGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDG-YPSLSTTTTIIIEVLDLNDNAPVF-LFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATL 2469
D N + I + DVNDN+P F V EN+ G + V A DLD N ++YSI N + F+I S GE+ ++ DRE+ Y + A D G+P+ + + ++D ND P F+ + T S E + QI A D DLG N + Y L + I G S G I+ G LDRE +S +V A D G Y S T + I VLD+NDN P+F +P V + G+T+ V+ D D G N I +SL N + F+I P + A + + L L + A D G P++++ +
Sbjct: 1821 DTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPG-VIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSAR-PLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFK---LSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQS---------------GLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPY----IGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLL--HLEVVARDKGNPPQSSLGLI 2150 HSP 8 Score: 94.3597 bits (233), Expect = 6.345e-19 Identity = 74/249 (29.72%), Postives = 116/249 (46.59%), Query Frame = 1
Query: 1444 PAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI----YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFL 2178
P ++S + I + D NDN+P+F K + V E N G+ V QV A D D+ +N + Y I++ N + A I G +++ I DRE D Y+ + A D G PQ+ + ++V+I D+ND P F + ++E+ + + I A D D + YRL + I S + + G + + LD E +L V A D + + T + + V D NDNAPVFL
Sbjct: 2300 PFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVTVSEA---TELGAVITSISANDVD--TYPALTYRLGAESTVDIENMSIFALD-------RYSGKLVLKRRLDYELQQEYELDVIASDAAHEA---RTVLTVRVNDENDNAPVFL 2533 HSP 9 Score: 92.4337 bits (228), Expect = 2.034e-18 Identity = 75/246 (30.49%), Postives = 115/246 (46.75%), Query Frame = 1
Query: 1474 INIIDVNDNAPRFVNKIKMFHVVENNP--IGSTVGQVRAMDLDSSNNGHIVYSIL--NSNDNFAIS--------IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVS-FDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAP 2169
+ + D NDNAP F EN P + T+ R +DL+ N Y+I+ N ND F +S +Y ++Q DRE T Y ++ A D G P L M V + IQD+ND P+F + YF + E+ + + Q+ A+D D +NG V+Y + ++ +++ + ++ GAI + LD E +L+V A D G L TT + I V D+NDN P
Sbjct: 162 VTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQR--YNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPEN---ATVGTSVLQVYASDTDADENGLVEYAI-----------NRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQP 391 HSP 10 Score: 78.5666 bits (192), Expect = 3.332e-14 Identity = 75/276 (27.17%), Postives = 116/276 (42.03%), Query Frame = 1
Query: 1666 GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGA----ISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIR 2478
GEI++K+K DRE SY V P ++ V V ++D ND P F + E+ +K L A D DL T +Y ++ GN + R DG + + G LDRE LL++A D G P L T+ I + D+NDN P+F + + F V +G ++ V D D NG + +++ + F+I P I + +F + L + L++ A D G+ P A + IR
Sbjct: 130 GEIRTKVKLDRETRASYSLVAI------PLSGRNIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLL---PARDLDLEPYNTQRYNIVS-------GN--VNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIF---NQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFET-KELHE-LVVVAKDHGEQPLETTAFVSIR 382 HSP 11 Score: 70.0922 bits (170), Expect = 1.558e-11 Identity = 68/246 (27.64%), Postives = 116/246 (47.15%), Query Frame = 1
Query: 1426 CVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS-NDNFAISIY------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIII 2139
C + S+Q F + + D NDN P+F + + EN P+GS+V + A DLD G + YSI + +D + ++ G + S FD E+ Y+ + A D G + S+ V+V+I+ ++ TP F E+ Y F + + + + Q+ ATD D G +G V Y+L S ++ +K+ DG ++Y +D +IS L++ A + SLS+ + I
Sbjct: 2834 CDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKKA--SVAVRVEIESRDEFTPQFTERTYRFVLPAAVALP-QGYVVGQVTATDSDSGPDGRVVYQLSAPHSHFKVNRSSGAVLIKRKLKLDGDGDGNLY--MDGRDIS---LVISASSGRHNSLSSMAVVEI 3071 HSP 12 Score: 51.2174 bits (121), Expect = 8.114e-6 Identity = 141/606 (23.27%), Postives = 245/606 (40.43%), Query Frame = 1
Query: 730 IDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVI---------SIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISV-----YTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKI-----KFDREKTDSYEF-VVTARDNGEP-----QLNDSMVVKVKIQDINDCTPVFEKD--YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSF-DGAISVYGNLDREE-ISSIQLLVQAFDDGYPS-LSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWE-IGKTICTVKTKDLDQGINGTITHSL--INSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLG 2439
+DRE + +IATD G TG+ T+ V + DVNDN P + +N V + E G ++ I AND D T L ++ T D + +S IF ++ L R + + + A+D T + + + D ND+ PV +I ++ E+ L TV D D N + + + + F+++ + R + +V Y V I D G PA+ S + D +F+ + E P+GS V Q+ LD S +I+ N+ A + +QSK DRE+ D Y+ +V + +G P + + V + I D ND P+F++ Y I+E +L+ I A D++ N V Y + GN + ++ + G + V LD + S +L+++A D + L + +E+ D NDN P F +V+ E E +G ++ DLD+G G + +S+ S++ F++ E ++ + + ++ + L+ ASD+G
Sbjct: 2386 LDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISANDVD---TYPALTYRLGAESTVDIENMS-IFALDRYSGKLVLKRRLDYELQQEYELDVIASDA-AHEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQ---------EGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQS------LAIIAGNEESAFEL---LQSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDA-DQENTPNSEVVYDITS-------GNDE------HMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPL----TEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELL--ASDMG 2947
BLAST of Protocadherin-11 X-linked vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 220.705 bits (561), Expect = 1.472e-58 Identity = 230/790 (29.11%), Postives = 364/790 (46.08%), Query Frame = 1
Query: 256 LPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSF-LDRETI--CENTKETCSMK-------LYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIG-NNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTE--------DRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFD--DNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN---FAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLN 2505
LP++ L K Y ++ +GD+ +DRET+ C N + C ++ L +Q I+ IE+ DINDN P F + +++ EN +G + +P+A DKD+ + GV Y + T G F ++ + + E++ P L ++ ++DRE S+ + A D GN + S + V++ D NDNAP++ K +Y+ + E G +L++ AND D NG + Y L + DR S I Y+ G L I NN++ Y+ A D + + ++T V I + D ND+ P + I ++ + E+ + VQV D+D+G N + C + L+ DN Y ++T T D E++ Y VEI VD GNPA+SS + + D NDN+P F + E N G V +V A D DS N +VYSI+ + F I GE++++ DRE D YEF VTA D G P + V +K+ D ND P F Y F + E+ + + D D G+N V+ + V+P ++ + + G I + DRE+ SS ++A D G P S+ + I VLD NDNAPV PSN+ +F+ +S + V+ +D+D G N + +S+ N + F I P GEI + KE + S RL+IK SD G+ ++ IA ++I ++ N++
Sbjct: 48 LPDTGH--LYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLKDCRNKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTL-------------TAGPEAVALFGLQVAEDRGEKL-PQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSD--LGPNGEIEYTLHQAIDPVPKLLRIDRS--SGIIYVKGP---LDREEI------NNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKRKYFLQTT--TPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPL---SPVGMVTVQDMDEGENAQVQ---LSVEP-----------DVGKFVIQNGTGTILSSISFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSNS-SFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGNPHDL--FYISPSNGEITLT---KELTRKHSGLHRLVIKVSDRGKPSRHAIALVHIYVNETIANVS 783
BLAST of Protocadherin-11 X-linked vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 221.09 bits (562), Expect = 2.551e-58 Identity = 230/790 (29.11%), Postives = 364/790 (46.08%), Query Frame = 1
Query: 256 LPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSF-LDRETI--CENTKETCSMK-------LYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIG-NNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTE--------DRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFD--DNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN---FAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLN 2505
LP++ L K Y ++ +GD+ +DRET+ C N + C ++ L +Q I+ IE+ DINDN P F + +++ EN +G + +P+A DKD+ + GV Y + T G F ++ + + E++ P L ++ ++DRE S+ + A D GN + S + V++ D NDNAP++ K +Y+ + E G +L++ AND D NG + Y L + DR S I Y+ G L I NN++ Y+ A D + + ++T V I + D ND+ P + I ++ + E+ + VQV D+D+G N + C + L+ DN Y ++T T D E++ Y VEI VD GNPA+SS + + D NDN+P F + E N G V +V A D DS N +VYSI+ + F I GE++++ DRE D YEF VTA D G P + V +K+ D ND P F Y F + E+ + + D D G+N V+ + V+P ++ + + G I + DRE+ SS ++A D G P S+ + I VLD NDNAPV PSN+ +F+ +S + V+ +D+D G N + +S+ N + F I P GEI + KE + S RL+IK SD G+ ++ IA ++I ++ N++
Sbjct: 48 LPDTGH--LYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLKDCRNKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTL-------------TAGPEAVALFGLQVAEDRGEKL-PQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSD--LGPNGEIEYTLHQAIDPVPKLLRIDRS--SGIIYVKGP---LDREEI------NNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKRKYFLQTT--TPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENM---PPLSPVGMVTVQDMDEGENAQVQ---LSVEP-----------DVGKFVIQNGTGTILSSISFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSNS-SFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGNPHDL--FYISPSNGEITLT---KELTRKHSGLHRLVIKVSDRGKPSRHAIALVHIYVNETIANVS 783
BLAST of Protocadherin-11 X-linked vs. Ensembl Zebrafish
Match: pcdh17 (protocadherin 17 [Source:ZFIN;Acc:ZDB-GENE-090608-3]) HSP 1 Score: 210.305 bits (534), Expect = 5.856e-55 Identity = 212/707 (29.99%), Postives = 333/707 (47.10%), Query Frame = 1
Query: 124 MLIELDILIIFSIKLVITLNVEFSVDENCRIGHVVGNVYSKLN-QLPNSSRSSLMKA--NEKDSYFSLNRTSGDLIVKSFLDRETIC-ENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNN---IRIYITATD--GNGRMNETSVDIAIEDCNDHPPVIS-IANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFD-----DNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAISIY-------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNER-------LEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEV 2145
M + + + ++ + + N+ +S+ E +I V+GN+ +L + S + N ++ SG L K +DRET+C +N+K SM+++ + D I +EI DINDN P F + Q I+I EN GT +PL A D D+ + G+KTY I R +++ F + +P L + +++DREE I+ ATD G ++G+ + V VTD NDN+P + + +Y V I E G I++L A D D+ NG V+Y S DR + ++F I+ + +I G I+ I I + A D N V + + D ND+ P I +A R G V E ++ V+V D+D GRNG +C + L N+ F DNF Y + T D DRE Y + I D GNP ++S + F++ I+D NDNAPRF + + V ENN G +G V A D D NG + YS+L SN +I+ Y G I + F+ E+T ++F V A+D+G P L + V+V + D+ND PV + ++ I R + ++A D D G++G + Y + D GN + E+ S G + L E ++L+++ D G PSLS +I++
Sbjct: 1 MHLSVFLFLLLWAQALTLKNLNYSIPEE-KIQGVIGNIAKDAELELGEQGKKSNFRVLENSAPHLIDVDPESGLLYTKQRIDRETLCRQNSKCQLSMEVFAN-DKEICMIKVEIQDINDNAPSFPSEQIDIDISENAAPGTRFPLAAAYDPDTKENGLKTYQITR--------------DDYSIFSLDVKSRGDGTKFPELVVQRSLDREERSHHTLIITATDGGEYPKSGTMQINVKVTDSNDNSPVFEQPSYVVEIPENAPLGTVIIDLNATDSDE--GINGQVTYSFSCYVPDR--IKELFSIDPRTGVI---KIQGKIDFEENPIIEIDVQAKDQGPNPIPGHCKVTVKVLDRNDNWPSIGFVAVRQGAVSEAATPGTVIALVRVTDKDSGRNGQLQCRI-------LGNVPFKLEENYDNF--YTVVT--DRPLDREVKDEYNITIVAKDNGNPPLNSTKSFTVKILDENDNAPRFTKMVYLLQVPENNIPGEYLGSVLAHDPDLGQNGTVSYSLLPSNVSEESITTYVNIKPTDGAIYALRSFNYEQTKYFDFKVQAKDSGNPHLESNTTVRVSVLDVNDNIPVI----VLPLLQNDTAEIHVPRNVGVGHIITTVRAVDNDFGESGRLTYEISD-------GNEEHLFEID-----SVTGEVRTAQPLWEEVTPVVELIIKVTDHGKPSLSAMAKLIVKA 657 HSP 2 Score: 169.859 bits (429), Expect = 2.606e-42 Identity = 172/589 (29.20%), Postives = 264/589 (44.82%), Query Frame = 1
Query: 781 FGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTK-NGLVSYQLSDRTEDRKIVSQIFYINGNKL---HLTNNRISGLINRNNIRIYITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGM----FECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPR--FVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS--------NDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP--SNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIR 2478
F N C + V + D+NDNAP + + ++I E + G L A DP+TK NGL +YQ++ +D I S G+ L R R++ + ITATDG + +++ + D ND+ PV + ++ EN ++ + D D+G NG F C + D K + D + KI+ D E+ + ++++ DQG + K ++ ++D NDN P FV ++ V E G+ + VR D DS NG + IL + DNF + + DRE D Y + A+DNG P LN + VKI D ND P F K Y ++ E+ +I E L + A D DLGQNGTV Y L+ P N ++ + DGAI + + E+ VQA D G P L + TT+ + VLD+NDN PV + P N+ ++V +G I TV+ D D G +G +T+ + + N+ F GE+ A + E LIIK +D G+ + +A L ++
Sbjct: 99 FANDKEICMIKVEIQDINDNAPSFPSEQIDIDISENAAPGTRFPLAA--AYDPDTKENGLKTYQIT--RDDYSIFSLDVKSRGDGTKFPELVVQRSLDREERSHHTLIITATDGGEYPKSGTMQINVKVTDSNDNSPVFEQPSYVVEIPENAPLGTVIIDLNATDSDEGINGQVTYSFSCYVPDRIK---ELFSIDPRTGVIKIQG----KIDFEENPIIEIDVQAKDQGPNPIPGHCKVTVKVLDRNDNWPSIGFV-AVRQGAVSEAATPGTVIALVRVTDKDSGRNGQLQCRILGNVPFKLEENYDNFYTVV-----TDRPLDREVKDEYNITIVAKDNGNPPLNSTKSFTVKILDENDNAPRFTKMVYLLQVPEN---NIPGEYLGSVLAHDPDLGQNGTVSYSLL-------PSNVSEESITTYVNIKPTDGAIYALRSFNYEQTKYFDFKVQAKDSGNPHLESNTTVRVSVLDVNDNIPVIVLPLLQNDTAEIHVPRNVGVGHIITTVRAVDNDFGESGRLTYEISDGNEEHLFEID-SVTGEVRTAQPLWEEVTPVV---ELIIKVTDHGKPSLSAMAKLIVK 656
BLAST of Protocadherin-11 X-linked vs. Ensembl Zebrafish
Match: si:ch73-233f7.7 (si:ch73-233f7.7 [Source:ZFIN;Acc:ZDB-GENE-141215-50]) HSP 1 Score: 199.134 bits (505), Expect = 2.761e-52 Identity = 210/695 (30.22%), Postives = 331/695 (47.63%), Query Frame = 1
Query: 142 ILIIFSIKLVITLNV-EFSVDENCRIGHVVGNVYSKLN-QLPNSSRSSL---MKANEKDSYFSLNRTSGDLIVKSFLDRETIC-ENTKETC--SMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQL--SDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATD--GNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL-----NSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESI-----KNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTI 2133
+L+ FS L +V +S+ E G VV N+ S L + SR + + +N+K Y +N+ +G+L V +DRE +C T TC M++ L+ I IEI DINDN P F+ ++I E+ G + L A D D +KTYY++ D E Q G+ F +K P +DREE S IL A D G ++G+ ++ V V D NDNAP++ KD+Y +N+ E G +++L A+D+D+ + + L SY L S++T+ Q F +N N + R+ LIN + RIY I ATD N + V I I D ND+ P ISI + V E+ ++ V V D+D G NG + ++ LK DN+ E DREK+ Y + I D+GNP +S + ++ ++DVNDN P+F V+ENN G+++ + A+D D N ++VY I+ N++ + SI G + + FD E + F + ARD+G P L+ ++ V + I D ND TP+ + + +E E+I K + ++ A D D N + Y+ + + + E+R + S+ + R++ +L+V A D+G P+LS T TI
Sbjct: 15 VLLFFSAILDTASSVTHYSIPEEMEEGSVVANLASDLGLDVATLSRRKMRLDIISNKK--YLDVNKETGELYVLEKMDREYLCLSKTATTCFIKMEVILENPVRIFNIEIEIVDINDNAPQFRRDTIHLDISESTAAGERFSLSNAVDPDIGSNSIKTYYLSESDHFDIEMQTGRDGSKFADLILKKP----------------LDREEQASHNLILTAVDGGVPARSGTASIIVRVLDTNDNAPQFDKDSYTINLTENAPIGSLVVKLNASDKDEGSNSDLLYSYSLYTSEKTQ------QTFSLNPNNGEI---RVKELINYEDFRIYDMEIIATDKGANSLTGKCKVKILITDMNDNHPEISIRSVTSPVKEDVAVNTVIAVVSVSDKDSGENGQVDIHISADLPFALK--ESSDNY----YELLVSEPLDREKLPEYDITITVTDRGNPPLSDNETITLELLDVNDNVPQFPQTFYTIPVMENNAPGASLSSITAVDPDLHENQYLVYFIIEKEIANTSMSMLFSINPENGNLYALKTFDYEIEKDFLFHIEARDSGVPPLSSNVTVHIIIMDQNDNTPLIVSPWRAQGSE-VKETIPRSTDKGTLIAKVIAIDSDSVHNSRITYQFLQNTDATLFSLDQYNGEIRTMRMFSYRDS--------RDQ----RLVVIAKDNGEPALSATVTI 663 HSP 2 Score: 108.997 bits (271), Expect = 1.399e-23 Identity = 135/568 (23.77%), Postives = 237/568 (41.73%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLH-LTNNRISGLINRNNIRIYITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNG--MFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHI--------VYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYF-FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNF---VNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHS 2490
AP++ +D ++I E + G+ L +N D N + +Y LS+ D + +G+K L + + + + +TA DG R S+ + + D ND+ P + + EN ++ + D+D+G N ++ SL S K + + N +++ + E +Y +EI D+G +++ K I I D+NDN P + V E+ + + + V D DS NG + +++ S+DN Y E+ DREK Y+ +T D G P L+D+ + +++ D+ND P F + ++ + E+ + L I A D DL +N + Y +I+ K I + L ++ + G + D E ++A D G P LS+ T+ I ++D NDN P+ + P + + G I V D D N IT+ + + F Q GEI TM+ FS S RL++ A D G+ + T+ + + +
Sbjct: 131 APQFRRDTIHLDISESTAAGERFSL-SNAVDPDIGSNSIKTYYLSE--SDHFDIEMQTGRDGSKFADLILKKPLDREEQASHNLILTAVDGGVPARSGTASIIVRVLDTNDNAPQFDKDSYTINLTENAPIGSLVVKLNASDKDEGSNSDLLYSYSLYTSEKTQ-QTFSLNPNNGEIRVKEL----INYEDFRIYDMEIIATDKGANSLTGKCKVKILITDMNDNHPEISIRSVTSPVKEDVAVNTVIAVVSVSDKDSGENGQVDIHISADLPFALKESSDN-----YYELLVSEPLDREKLPEYDITITVTDRGNPPLSDNETITLELLDVNDNVPQFPQTFYTIPVMEN---NAPGASLSSITAVDPDLHENQYLVYFIIE-KEIA-------NTSMSMLFSINPENGNLYALKTFDYEIEKDFLFHIEARDSGVPPLSSNVTVHIIIMDQNDNTPLIVSPWRAQGSEVKETIPRSTDKGTLIAKVIAIDSDSVHNSRITYQFLQNTDATLFSLD-QYNGEI---RTMRMFSYRDSRDQRLVVIAKDNGEPALSATVTIKLSTVET 670 HSP 3 Score: 103.219 bits (256), Expect = 9.016e-22 Identity = 123/469 (26.23%), Postives = 195/469 (41.58%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGM--FECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI-------------LNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIK-NERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEW--EIGKTICTVKTKDLDQGINGTITHSLIN---SNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLI-IKASDLGQNPKNNIATLYI 2475
++I I D ND+ P + E+ + D D G N + + S +D + ++ R FA ++ DRE+ + + + + VD G PA S + ++D NDNAP+F ++ EN PIGS V ++ A D D +N ++YS LN N+ GEI+ K + E Y+ + A D G L VK+ I D+ND P +T E + N + + +DKD G+NG V + P + +S EL V LDRE++ + + D G P LS TI +E+LD+NDN P F F + V G ++ ++ D D N + + +I +N + F I PE + A +K F ++ D L I+A D G P ++ T++I
Sbjct: 120 IEIEIVDINDNAPQFRRDTIHLDISESTAAGERFSLSNAVDPDIGSNSIKTYYLSESDHFDIEMQTGRDGSKFADLILKK----PLDREEQASHNLILTAVDGGVPARSGTASIIVRVLDTNDNAPQFDKDSYTINLTENAPIGSLVVKLNASDKDEGSNSDLLYSYSLYTSEKTQQTFSLNPNN-------GEIRVKELINYEDFRIYDMEIIATDKGANSLTGKCKVKILITDMNDNHPEIS---IRSVTSPVKEDVAVNTVIAVVSVSDKDSGENGQVDIHISADLPFALKESSDNYYELL------------VSEPLDREKLPEYDITITVTDRGNPPLSDNETITLELLDVNDNVPQF-----PQTFYTIPVMENNAPGASLSSITAVDPDLHENQYLVYFIIEKEIANTSMSMLFSINPENGNLYA--LKTF-DYEIEKDFLFHIEARDSGVPPLSSNVTVHI 554
BLAST of Protocadherin-11 X-linked vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 201.06 bits (510), Expect = 2.947e-52 Identity = 198/700 (28.29%), Postives = 318/700 (45.43%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRI---YITATDGNGRMNETS---VDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN---DNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNL--DREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSN-NMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLN 2505
F + ++I EN +G + +PVA D+DS G+ Y A G + N F ++ + E++ P L ++ N+DRE S+ + D G+ + S + + +TD NDN P++ + +Y+ + E G +L++ AND D NG V+Y L + V ++ I+ N + + G ++R I I Y+ A D NG +++S V I ++D ND+ P I I + + E+ + V+V D D+G N + C + L++ N K T D E+I Y +EI VD GNPA+SS + + D+NDNAP F + E N G V V A D DS N + YSI + F I+ GE++ + DRE+ D Y+F+V A D G P L + V VK+ D ND P F Y F + E+ + + D D G+N V+ + P N K + +G ++ + DRE+ S+ ++A D G P S+ I I VLD NDNAP P+N + F++ E + +V+ +D+D G+N + +++ N F+I EGEI +A KEF+ RL++K D G P+ A ++I ++ N++
Sbjct: 141 FSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADY--ALTTGPEATN----------LFSLQVAQDSDEKL-PQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSD--MGPNGEVTYSLH---QPSSPVMRLLSIDRNTGIIF---VKGSVDREEISILKFYVQAKD-NGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPL---SPVGMVTVNDHDEGENARVQLSV-------EPDNGKFMIQ---------NGTYTILSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPET--HVESVEAEDIDIGLNSELDFNIVGGNPHGL--FRISSEGEITLA---KEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYVNETIGNVS 792 HSP 2 Score: 128.257 bits (321), Expect = 1.677e-29 Identity = 128/467 (27.41%), Postives = 203/467 (43.47%), Query Frame = 1
Query: 1141 IAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKL-NLKNIRFDDNFAIYKIETYPD----TSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFA--ISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERL------EQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQP-EGEIIIAHTM--KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYI 2484
I I D ND+ P S + EN + D D G NG+ + +L + NL F A E P + DRE Y + IK VD G+P S I I D NDN P+F + EN+P+G +V QV+A D D NG + YS+ + +SI G I K DRE+ +F V A+DNG + +V + ++D ND P +T G + +E + ++ +D+D G+N V V +P + +E N K + + LD E I ++ + A D G P+LS+T ++ ++V D+NDNAPVF S + V E + G + V D D G N +T+S+ + E F+I P GE+ + + ++ ++ + ++ A+D G AT+ ++ +
Sbjct: 129 IEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNL----FSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTC----VVAGDVPFQLRSASETGNDRKRKY--FLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVF---SPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGL-FEINPNTGEVRVMSQLDREQLDHY-----QFLVAAADKGVPSLRGTATVVVKVL 576
BLAST of Protocadherin-11 X-linked vs. Ensembl Xenopus
Match: ENSXETT00000027070.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:19099783:19110965:-1 gene:ENSXETG00000013163.1 transcript:ENSXETT00000027070.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 221.861 bits (564), Expect = 4.202e-59 Identity = 233/824 (28.28%), Postives = 391/824 (47.45%), Query Frame = 1
Query: 172 ITLNVEFSVDENCRIGHVVGNVYSKLNQLPN--SSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKL--YLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLIN---RNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS-NDNFAISIY-------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEI-------GKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSIGKKSHSSDNNNFGFRL 2565
+ +++S+ E R+G+V+GN+ + L SSR + + K Y +++ +GDL V +DRE +C ++ C + + ++ H I +EI D+NDN P F + I+I E +GT + L A+D D +++Y ++ +V T G YP L + K +DRE+ S V IL A D G ++TG+ + ++VTD+NDN P + KD Y+V + E G +++L A D D+ N ++Y +D E+ + ++F IN + +I+G ++ N + + A DG G ++ + I + D ND+ P I I + + E+ + ++ V + D D G NG +++S +L I N+ YK+ T D DREK S Y + IK D+G+P +++ + + + DVNDNAP F + ++ ENNP G++ +V A D D + NG +VY IL ++ IS Y G + ++ FD EK EF + A D G PQL ++ +++ + D+ND PVFEK DY I E+ + ++ ATD D+ +NG V Y ++ +P +S + + G + + D E + + V A D G PS S T+ I + D NDNAP L+PS + +V +E G + V D D G N +++ L+ +F Q GEI I ++E R R+++ D G ++ TL + + + P + + ++N F L
Sbjct: 30 VICQLQYSIYEEQRLGYVIGNIANDLGVSAEELSSRKFHIVSRSKKQYLNVHLENGDLYVADRIDREALC-GMQQNCFLNIEAVMESPLHFYTINVEIQDVNDNSPSFSKSIFEISISELAVVGTHFALGSAKDPDLGNNSIQSYKLSANDYFGMLEKVNTDGRK----------------YPELVLEKTLDREKKNSSVLILSAFDGGTPSKTGTSLIRIVVTDINDNYPLFNKDTYRVTVSENVPIGFLVIDLHATDADE--GSNAEITYLFNDIPENAQ---EVFAINPENGSV---QITGKLDYEVATNYEMTVEAKDGGGLVSYCKLLIQVSDVNDNAPDILITSFSDIIPEDSRVGTVIALVNLDDLDSGENGEVVGQISESLPFHL--ISSSGNY--YKLVTSMD--LDREKTSEYNITIKAEDKGSPQLTNSKTIRLILTDVNDNAPVFDKMDYVAYIQENNPSGNSFYRVHATDPDINENGKVVYMILTDIIEDIPISSYVSINTVSGVLYAQRSFDYEKLR--EFYIQAEDKGSPQLTNNKTIRLILTDVNDNAPVFEKMDYVAYIQEN---NPSGSSFFRVHATDSDINENGKVVYMILTDIIEDMPLSSYISIN-------TVSGVLYAQRSFDYESLREFYIQVMAKDSGSPSRSANATVKICITDQNDNAPKILYPSQDSEAASV---FEFIPHFSTKGYLVTKVVAVDADSGHNAWLSYHLLQV-PDPSFLIIGQNTGEIRITRDLQETDALRQ---RIVVMVKDNGYPMLSSTVTLNLVVAENFQQVLPEITNQHIDTESSSNATFYL 803
BLAST of Protocadherin-11 X-linked vs. Ensembl Xenopus
Match: ENSXETT00000027042.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:19134998:19145586:-1 gene:ENSXETG00000013174.1 transcript:ENSXETT00000027042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 213.001 bits (541), Expect = 1.139e-56 Identity = 209/726 (28.79%), Postives = 345/726 (47.52%), Query Frame = 1
Query: 124 MLIELDILIIFSIKLVITLNVEFSVDENCRIGHVVGNVYSKLNQLPN--SSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETC--SMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXX--APEWTKDNYKVNIQE-CQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI--------SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-------EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSI--QLLVQAFDDGYPSLSTTTTIII------EVLDLNDNAPVFLFPSNNMNF 2202
++ ++ I I+ +I +++SV E + G ++GN+ + LN N S R + ++++ + S+N +GDL V+ +DRET+C + C +K ++ I +EINDINDN P F + + E G + L AQD D V++Y ++ + +F + S YP L + K++DRE+ S LI +D G+ +CT +V + + N P +T+D Y VNI E + +L+L A D DD N ++Y S E+ + QIF IN + R +G ++ + Y + A DG G ++ V I + D ND+ P I I++ + E+ + ++ D D G NG C + S +L + I +N+ YKI T + DRE+ + Y +EI D+G+P + S + + I DVNDNAP F + +V ENNP G+++ ++ A DLD + NG I+YSI+++N A+ S G + + FD E+ + F V ARD+G P LN S+ V++ I D ND P E+ F Y S K + ++ A D D G N + Y + V + + E+R IS D +E+ S+ +++V D+G PSL+ T + + +VL +N P+ L ++N+ F
Sbjct: 10 VIWQVHIFILCIFYKMIYGQIQYSVYEELKPGSIIGNIANDLNLSINELSVRKFHIASHDRKQFISVNLDNGDLFVRERIDRETLC-GLEPQCILDLKAMIENPLQIFTIKVEINDINDNEPSFSKKSFEVEVSEFAVPGARFALDYAQDPDLGTNSVQSYGLSANK----------------YFSLGERTSSDGSKYPELVLEKHLDREKQSSLELSLIPSDGGSPKKTCTASVKIVVHDANDNYPVFTQDTYVVNINEDAPNSFLVLQLQAADEDD--GTNAQITYSFSHIPENAR---QIFTINPQTGEI---RKTGHLDYEVTKRYTITVEARDGGGLVSPCKVSIQVIDANDNAPEIQISSYSATIPEDAPTQTVIAIFNTYDMDSGENGKVVCQI--SEELPFQLISLTENY--YKIMT--SSRMDREETAEYNIEITAKDKGSPPLYSNKTIQLTISDVNDNAPVFEKPSYIAYVPENNPPGTSIHRINASDLDLNENGQIMYSIISNNTEDALVSSHVSINSGTGVVYALHSFDYEQIREFSFQVMARDSGSPPLNSSVTVRICIVDRNDNAPKILYPSLDSERTALFEFIPRY--STKGYLVTKVIAVDADTGHNAWLSYHFLQVPEPSMFTIGQHTGEIR----------IS----RDFQEVDSLKQKIVVLVKDNGDPSLTATVALNLVIAENFQVLPELNNQPIKLETTSNITF 688 HSP 2 Score: 64.3142 bits (155), Expect = 1.186e-9 Identity = 62/201 (30.85%), Postives = 90/201 (44.78%), Query Frame = 1
Query: 1768 MVVKVKIQDINDCTPVFEKDYF-FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSL--INSNKRENFPFKIQPE-GEI 2358
+KV+I DIND P F K F ++E ++ R A D DLG N Y G+ N R S + + +LDRE+ SS++L + D G P + T ++ I V D NDN PVF + + VN++ + + ++ D D G N IT+S I N R+ F I P+ GEI
Sbjct: 116 FTIKVEINDINDNEPSFSKKSFEVEVSEF---AVPGARFALDYAQDPDLGTNSVQSY--------GLSANKYFSLGERTSSDGSKYPELVLEKHLDREKQSSLELSLIPSDGGSPKKTCTASVKIVVHDANDNYPVF---TQDTYVVNINEDAPNSFLVLQLQAADEDDGTNAQITYSFSHIPENARQI--FTINPQTGEI 300
BLAST of Protocadherin-11 X-linked vs. Ensembl Xenopus
Match: vat1l (vesicle amine transport 1-like [Source:Xenbase;Acc:XB-GENE-952539]) HSP 1 Score: 202.216 bits (513), Expect = 4.971e-53 Identity = 198/685 (28.91%), Postives = 321/685 (46.86%), Query Frame = 1
Query: 169 VITLNVEFSVDENCRIGHVVGNVYSKL--NQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKL--YLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAISIY-------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTP-------VFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLD 2151
+T + +S+ E + G+ VGN+ L N + R + + + +F +N +G+L V +DRE++CE C ++L ++ + + +EI DINDN P F I EN P GT + L AQD D+ ++TY I+ EN+ FF++ S YP L + K +DRE+ + IL A D G +TG+ + + +TDVNDN P ++K+ Y VN+ E + D L + N D NG + Y S + KI Q F I+ H R G ++ + Y + A DG G + T V I + D ND+ P I + + + E+ ++ + ++D D G NG C + DS L + N+ Y + T + DRE++ Y + IK D+G+ +S+ + + I+DVNDNAP F + ++ ENNP GS++ QV+A D D NN IVYS ++ N + +S Y G + ++ FD E+ + + A+DNG P LN +++VK+ + D ND +P V E F I K E + ++ A D D G N + Y+ + + E+R L +V +E + +++V D+G P S+T + + V D
Sbjct: 29 AVTAQLHYSILEEEKKGYFVGNIAKDLGLNTQDLAKRKFRISSVTAEHFFHVNLENGNLYVADRIDRESVCE-MAPICLLRLKAVVENPLYVFHVEVEIQDINDNSPSFSRKNMNFEILENTPTGTRFVLGNAQDPDTGINTLQTYKIS-------ENE---------FFKLNEKTSTDGRKYPELVLEKPLDREKQSALEIILTALDGGTPIKTGTAIIKISITDVNDNTPMFSKEVYPVNLPE-NAPVDTLVICLNATDADEGVNGHILYSFSHIS---KIAQQTFTIDS---HTGEIRTKGTLDFEITKAYEMIVEAQDGGGLFSHTKVVIQVLDTNDNAPEIILTSVSNSIPEDSLPGTVVALIDIQDMDSGENGNVYCQITDSLPFALTS--SSSNY--YTLVT--TGTLDREEMPEYNITIKATDRGSLPLSTTKTIRLVILDVNDNAPIFEQPSYVVYIPENNPSGSSIFQVQASDPDLDNNAKIVYSTVHKNASDVPVSSYISLNSITGVLYAQRPFDYEQMREFTIQIMAKDNGSPPLNSTVIVKICVTDRNDNSPKILYPSSVVEDSAQFEIVPRSAN--KGELIAKVVAVDADSGHNAWLSYQFLQPSEPSYFSIGRHTGEIRTL-RV-----------FQEKETTKHKVIVLVKDNGNPPRSSTINLNLVVAD 669 HSP 2 Score: 139.428 bits (350), Expect = 5.974e-33 Identity = 123/404 (30.45%), Postives = 186/404 (46.04%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGM--FECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILN----SNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGE-SIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRE 2322
V++ I+D ND+ P S N ++LEN +D D G N + ++ S N+ KLN K + E + DREK S + + +D G P + I+I DVNDN P F ++ ++ EN P+ + V + A D D NGHI+YS + + F I S GEI++K D E T +YE +V A+D G L V +++ D ND P + ++ S E S+ + I D D G+NG V ++ D P + +S + L+ G LDREE+ + ++A D G LSTT TI + +LD+NDNAP+F PS V + G +I V+ D D N I +S ++ N +
Sbjct: 122 VEVEIQDINDNSPSFSRKNMNFEILENTPTGTRFVLGNAQDPDTGINTLQTYKISENEFFKLNEKTSTDGRKYP----ELVLEKPLDREKQSALEIILTALDGGTPIKTGTAIIKISITDVNDNTPMFSKEVYPVNLPENAPVDTLVICLNATDADEGVNGHILYSFSHISKIAQQTFTIDSHTGEIRTKGTLDFEITKAYEMIVEAQDGG--GLFSHTKVVIQVLDTNDNAP---EIILTSVSNSIPEDSLPGTVVALIDIQDMDSGENGNVYCQITDSLPFALTSSS---SNYYTLVTT---------GTLDREEMPEYNITIKATDRGSLPLSTTKTIRLVILDVNDNAPIFEQPS---YVVYIPENNPSGSSIFQVQASDPDLDNNAKIVYSTVHKNASD 501
BLAST of Protocadherin-11 X-linked vs. Ensembl Xenopus
Match: ENSXETT00000027771.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:18279501:18292255:1 gene:ENSXETG00000012600.1 transcript:ENSXETT00000027771.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 202.601 bits (514), Expect = 6.105e-53 Identity = 194/717 (27.06%), Postives = 332/717 (46.30%), Query Frame = 1
Query: 121 RMLIELDILIIFSIKL-VITLNVEFSVDENCRIGHVVGNVYSKLN----QLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPI----------------GTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQE-CQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAISIY-------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGE-----SIKNERLEQIKATDKDLGQNGTVKYRLIDV---KPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLD 2151
RM ++ +FS +++ + +S+ E R V+ N+ + L QL S+R + + + YFS++ +G+L VK +DRET+C TC +L D + + + VF K+ +I +N P+ G + L A+D D V+TY ++ + Q+F + S +P L + + +DRE +L A+D G +TG+ + V+VTD NDN P +T++ YKV+I E +L + A+D D+ N ++Y S RT + + +F IN +T N + + + I + A DG G + + V I I D ND+ P ISI + F + E+ ++ ++V D+D +N +C + S L + D F Y+I T ++ DREK S Y + I D+G+P +SS + ++I+DVNDN P F+ + ++ ENN G+++ ++ A+DLD +N ++YSI N+N ++F +S Y G + ++ FD E+ + + A+DNG P L+ + V ++I D ND P S E S++ + ++ A D D G N + Y I + P I ++ G I L ++ +++V D+G+P+LS T TI + V D
Sbjct: 5 RMRWQVTFSFLFSWFCHLVSGQLHYSIAEELRKDSVIANIANDLGLDIKQL--STRRLRIVSRVSEKYFSVDSENGNLYVKDRIDRETLC-GKDTTC----FLTFDA----------VVANPLNVFTVKIKIEDINDNPPVFFNDIVTLEMIELTLPGKQFVLQTAEDPDIGSNSVQTYKLS----------------DNQYFTLNEKTSSGGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDE--GTNAQITYSFS-RTSVNSLHASMFSINPTSGEITTNNLLNFEAKKDYEISVQAKDGGGFVAHSKVLIEITDENDNAPEISITSLFTPIPEDTTPGTVIALIEVHDQDSEQNAEVDCQILGSAPFQL--VSSSDRF--YRIIT--SSALDREKASWYNITILATDRGSPELSSRKFIRLDILDVNDNPPIFIKSVYNVYLPENNLPGASIYRIHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETGVLYAQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTVIIRIMDQNDNAPKMLYPSIESGDSSQFEMVPFTSVEGSLITKVVAVDADSGHNSWLSYHFIQISESSPFSINQHT---------------GEIRTSRVLQEKDALKHKVIVMIKDNGHPTLSVTATINLVVAD 664 HSP 2 Score: 129.413 bits (324), Expect = 9.246e-30 Identity = 140/539 (25.97%), Postives = 228/539 (42.30%), Query Frame = 1
Query: 910 ELIANDRDDPNT-KNGLVSYQLSDRTEDRKIVSQIFYIN------GNKL-HLTNNRISGLINRNNIRIYITATDGNG--RMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPS----NNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI-QPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATL 2469
+ + +DP+ N + +Y+LSD +Q F +N G+K L R +N + +TA+DG R + + + D ND+ PV + + EN + V D D+G N S + + +L F N +I T +F+ +K Y + ++ D G + K I I D NDNAP + E+ G+ + + D DS N + IL S +S + I + DREK Y + A D G P+L+ +++ I D+ND P+F K Y + E+ ++ + +I A D D+G N V Y + + P +S + G + + D E+ + + A D+G PSLS+ TT+II ++D NDNAP L+PS ++ F V G I V D D G N +++ I + E+ PF I Q GEI + ++E +L ++I+ D G + AT+
Sbjct: 147 QFVLQTAEDPDIGSNSVQTYKLSD--------NQYFTLNEKTSSGGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTNNLLNFEAKKD--YEISVQAKDGG--GFVAHSKVLIEITDENDNAPEISITSLFTPIPEDTTPGTVIALIEVHDQDSEQNAEVDCQILGSAPFQLVSSSDRFYRIITSSALDREKASWYNITILATDRGSPELSSRKFIRLDILDVNDNPPIFIKSVYNVYLPEN---NLPGASIYRIHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIET-------GVLYAQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTVIIRIMDQNDNAPKMLYPSIESGDSSQFEMVPFTSVEGSLITKVVAVDADSGHNSWLSYHFIQIS--ESSPFSINQHTGEIRTSRVLQEKD---ALKHKVIVMIKDNGHPTLSVTATI 658
BLAST of Protocadherin-11 X-linked vs. Ensembl Xenopus
Match: ap4b1 (adaptor related protein complex 4 subunit beta 1 [Source:Xenbase;Acc:XB-GENE-949306]) HSP 1 Score: 201.06 bits (510), Expect = 1.055e-52 Identity = 213/721 (29.54%), Postives = 342/721 (47.43%), Query Frame = 1
Query: 142 ILIIFSIKLVITLNVEFSVDENCRIGHVVGNVYSKLN----QLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETC--SMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYIT--ATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVL-ENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS-------NDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGE--------SIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIII------EVLDLNDNAPVFLFPSNNMNF 2202
+ +F + V++SV E G ++GN+ + LN +L S R + + ++ Y S+N SGDL V +DRET+C T+E C MK + H + +EI DINDN P+F + I E+ G + L AQD D V++Y ++ N+ +G KNP+ L + K +DRE+ S +L A+D G+ +TG+ + ++V D NDN P +++D Y VNI E G +L+L A D DD NG ++Y S E+ IF I+ L+ ++ L R IT A DG ++ V + + D ND+ PVI I N F + E+ + ++ +++ D D G NG C + D L + I DN+ YKI + + DRE+ S Y + I D+G P++ + + + + D+NDN+P F + +V ENN G++V + A+DLD + NG I YSI+++ + + +I S G + + FD EK F V A D+G P L+ ++ V+V I D ND P + +++ G S K + ++ A D D G N + Y L+ V+ I + G I + +L+ + S +L+V D G PSLS T T+ + +VL +N P+ L ++N+ F
Sbjct: 10 VFFLFYLYETFAGQVQYSVYEESEQGFIIGNIANDLNMDIEEL--SDREFQIVSQDQKQYISVNLESGDLFVTERIDRETLC-GTEEECFLDMKALMVNPLHIYTVKVEIEDINDNAPIFSKNYFEVGISESALPGARFALGYAQDPDLGSNSVQSYGLST-------NEYFILGERISSDGSKNPE---------LVLEKPLDREKQNSIELMLTASDGGSPRKTGTALIKIVVYDANDNYPVFSQDTYVVNINENAPNGSLVLQLHATDEDD--GSNGEITYSFSHIPENAL---HIFRIDSQTGELS--KVGELDYEVTKRYTITVEAKDGGDLVSHCKVSVQVVDANDNAPVI-IVNSFSSAISEDSPPETVIALIRIYDGDTGENGEIVCQIPD--ILPFQLISLTDNY--YKIVSL--SRLDREQRSAYNITILAKDKGLPSLCNNKTLQVTLTDINDNSPVFDKTNYIAYVPENNHPGTSVLHITALDLDINENGKITYSIISTAIQGIPVSSHVSINSATGVVYALHAFDYEKIRELHFQVMAEDSGSPSLSSNVSVRVCIIDWNDNYP----KILYPSSDAEGAIYEFIPLPSEKGYLVTKVIAVDADSGHNAWLSYHLLQVQEPSI------------FVIGHHTGEIRLARDLEETDSSRQKLVVMVKDSGEPSLSATVTLNLIVAESFQVLPETNNKPIKLDTTSNITF 681 HSP 2 Score: 77.411 bits (189), Expect = 9.610e-14 Identity = 64/181 (35.36%), Postives = 88/181 (48.62%), Query Frame = 1
Query: 1774 VKVKIQDINDCTPVFEKDYF-FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGA----ISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSL 2301
VKV+I+DIND P+F K+YF I+ES ++ R A D DLG N Y G+ N R +S DG+ + + LDRE+ +SI+L++ A D G P + T I I V D NDN PVF S + VN++ G + + D D G NG IT+S
Sbjct: 112 VKVEIEDINDNAPIFSKNYFEVGISES---ALPGARFALGYAQDPDLGSNSVQSY--------GLSTNEYFILGER----ISSDGSKNPELVLEKPLDREKQNSIELMLTASDGGSPRKTGTALIKIVVYDANDNYPVF---SQDTYVVNINENAPNGSLVLQLHATDEDDGSNGEITYSF 274
BLAST of Protocadherin-11 X-linked vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 233.032 bits (593), Expect = 2.139e-62 Identity = 204/699 (29.18%), Postives = 315/699 (45.06%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNI---RIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIR--FDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNL--DREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM-KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTN 2499
F + + I EN IG+ +P+P+A D+D+ GV +Y E Q Q+ QEE P L ++ N+DRE + S+ + D GN + S + V V D NDNAP++ + Y+ + E G ++++ AND D N + Y E +V ++ ++ N +T + G ++R ++ R + A D + V + ++D ND+ P I I + + E+ ++ + VQV D D+G N C + L+ D+ Y ++T T D EK+ YT+EI VD GNP +SS + ++DVNDNAP F I ENN G V +V A D DS +N +VYS+ + F IS GEI+ K DRE+ DSYE V A D G P L + V V + D ND P F Y F + E+ + + D D G+N V +L E N V +G ++ +L DRE+ S+ ++A D G P S + I VLD NDNAP PSN + + ++ + +G+T+ V +D+D GIN +T+S+ N P+ + G A T+ KE RL++K SD G+ P+ A +++ +L N
Sbjct: 7 FASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASY----------ELQAGPEAQELFGLQVAE---DQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSD--QGANAEIDYTFHQAPE---VVRRLLRLDRNTGLIT---VQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTT--TPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENM---PALSPVGMVTVIDGDKGENARV----------------QLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRL-LTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGN-----PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLAN 657 HSP 2 Score: 101.293 bits (251), Expect = 4.376e-21 Identity = 76/284 (26.76%), Postives = 127/284 (44.72%), Query Frame = 1
Query: 1492 NDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISIYGEIQSKIK-------FDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFL-----FPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTIT 2292
NDN P F + + + EN IGS A D D+ NG Y + + + F + + + + K DRE+ DSY+ + +D G P S +++V + D ND P FE+ Y ++E+ S + Q+KA D D G N + Y + +R L+++ + G I+V G +DRE++S+++ V A D G S +++ V D+NDNAP ++ N+S + + V+ D D+G N +T
Sbjct: 1 NDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSEN---SPIGHSVIQVKANDSDQGANAEIDYTFHQAPEV-----------VRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVT 270
BLAST of Protocadherin-11 X-linked vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 232.261 bits (591), Expect = 3.135e-62 Identity = 204/699 (29.18%), Postives = 315/699 (45.06%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNI---RIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIR--FDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNL--DREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM-KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTN 2499
F + + I EN IG+ +P+P+A D+D+ GV +Y E Q Q+ QEE P L ++ N+DRE + S+ + D GN + S + V V D NDNAP++ + Y+ + E G ++++ AND D N + Y E +V ++ ++ N +T + G ++R ++ R + A D + V + ++D ND+ P I I + + E+ ++ + VQV D D+G N C + L+ D+ Y ++T T D EK+ YT+EI VD GNP +SS + ++DVNDNAP F I ENN G V +V A D DS +N +VYS+ + F IS GEI+ K DRE+ DSYE V A D G P L + V V + D ND P F Y F + E+ + + D D G+N V +L E N V +G ++ +L DRE+ S+ ++A D G P S + I VLD NDNAP PSN + + ++ + +G+T+ V +D+D GIN +T+S+ N P+ + G A T+ KE RL++K SD G+ P+ A +++ +L N
Sbjct: 146 FASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASY----------ELQAGPEAQELFGLQVAE---DQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSD--QGANAEIDYTFHQAPE---VVRRLLRLDRNTGLIT---VQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTT--TPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPAL---SPVGMVTVIDGDKGENARV----------------QLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRL-LTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGN-----PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLAN 796 HSP 2 Score: 106.686 bits (265), Expect = 9.043e-23 Identity = 88/337 (26.11%), Postives = 147/337 (43.62%), Query Frame = 1
Query: 1375 DTSFDREKIS-----------VYTVEIKCVD---QGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISIYGEIQSKIK-------FDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFL-----FPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTIT 2292
+TS DRE + + E+ D G+P + Q I + D+NDN P F + + + EN IGS A D D+ NG Y + + + F + + + + K DRE+ DSY+ + +D G P S +++V + D ND P FE+ Y ++E+ S + Q+KA D D G N + Y + +R L+++ + G I+V G +DRE++S+++ V A D G S +++ V D+NDNAP ++ N+S + + V+ D D+G N +T
Sbjct: 90 ETSIDREGLRECQNQIPGNPCILEFEVSITDLVQNGSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSEN---SPIGHSVIQVKANDSDQGANAEIDYTFHQAPEV-----------VRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVT 409
BLAST of Protocadherin-11 X-linked vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 232.261 bits (591), Expect = 3.135e-62 Identity = 204/699 (29.18%), Postives = 315/699 (45.06%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNI---RIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIR--FDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNL--DREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM-KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTN 2499
F + + I EN IG+ +P+P+A D+D+ GV +Y E Q Q+ QEE P L ++ N+DRE + S+ + D GN + S + V V D NDNAP++ + Y+ + E G ++++ AND D N + Y E +V ++ ++ N +T + G ++R ++ R + A D + V + ++D ND+ P I I + + E+ ++ + VQV D D+G N C + L+ D+ Y ++T T D EK+ YT+EI VD GNP +SS + ++DVNDNAP F I ENN G V +V A D DS +N +VYS+ + F IS GEI+ K DRE+ DSYE V A D G P L + V V + D ND P F Y F + E+ + + D D G+N V +L E N V +G ++ +L DRE+ S+ ++A D G P S + I VLD NDNAP PSN + + ++ + +G+T+ V +D+D GIN +T+S+ N P+ + G A T+ KE RL++K SD G+ P+ A +++ +L N
Sbjct: 146 FASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASY----------ELQAGPEAQELFGLQVAE---DQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSD--QGANAEIDYTFHQAPE---VVRRLLRLDRNTGLIT---VQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTT--TPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPAL---SPVGMVTVIDGDKGENARV----------------QLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRL-LTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGN-----PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLAN 796 HSP 2 Score: 106.686 bits (265), Expect = 9.043e-23 Identity = 88/337 (26.11%), Postives = 147/337 (43.62%), Query Frame = 1
Query: 1375 DTSFDREKIS-----------VYTVEIKCVD---QGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISIYGEIQSKIK-------FDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFL-----FPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTIT 2292
+TS DRE + + E+ D G+P + Q I + D+NDN P F + + + EN IGS A D D+ NG Y + + + F + + + + K DRE+ DSY+ + +D G P S +++V + D ND P FE+ Y ++E+ S + Q+KA D D G N + Y + +R L+++ + G I+V G +DRE++S+++ V A D G S +++ V D+NDNAP ++ N+S + + V+ D D+G N +T
Sbjct: 90 ETSIDREGLRECQNQIPGNPCILEFEVSITDLVQNGSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSEN---SPIGHSVIQVKANDSDQGANAEIDYTFHQAPEV-----------VRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVT 409
BLAST of Protocadherin-11 X-linked vs. Ensembl Mouse
Match: Pcdhga10 (protocadherin gamma subfamily A, 10 [Source:MGI Symbol;Acc:MGI:1935227]) HSP 1 Score: 213.386 bits (542), Expect = 2.065e-56 Identity = 200/681 (29.37%), Postives = 316/681 (46.40%), Query Frame = 1
Query: 184 VEFSVDENCRIGHVVGNVYSKLNQLPN--SSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKET-CSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAISIY-------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITE-SYGESIKNERLE------QIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLD 2151
+ +SV E G VGN+ L P + R + + + FSLN G L+ +DRE +C + S + ++ I IE+ D+NDN P FQ + I EN+ G +PLP A D D +++Y ++ +N F + +K + YP L + + +DREE +L+A+D GN ++G+ +TV V D NDNAP +T Y+VNI E G +L++ A D+D+ NG V+Y + + +Q+ +K H +IS ++ + Y I A DG + V I +ED ND+ P ++I + F V E+ ++ + V D D G+NG CS+ SG L K + DN+ Y++ T + DRE++ Y + + D GNP +S+ F++ + D+NDN P F + ++ ENNP G+++ V A+D DS N IVYS+ + +S Y G + + FD E+ + VTA D+G+P L+ ++ + + + D ND +P E Y T+ S G + E ++ A D+D GQN + YRL LKA L V G + L + L+V D G P LS T T+ + V D
Sbjct: 29 IRYSVPEELEKGSFVGNIAKDLGLEPRQLAERGVRIISRGRSQLFSLNPRGGSLVTAGRIDREELCAQSAPCLVSFNILVEDRVKLFGIEIEVTDVNDNAPKFQAETLDVKINENVAPGMRFPLPEATDPDVGVNSLQSYQLS---------------SNKHFSLVVQSGAKGVK-YPELVLEQALDREEEAIHHLVLVASDGGNPPRSGTVLITVTVFDANDNAPVFTSTEYRVNIPENLPVGTQLLKVTATDKDE--GANGEVTYAFR-----KSLDTQLSKFQLDK-HTGEIKISENLDYEEMSFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPEVTITSLFSPVTEDSPVGTVIALLNVHDLDSGQNGEVACSI--SGNLPFKLEKSIDNY--YRLVT--QRALDREQVPAYNITVTATDGGNPPLSTKADFTLQVADINDNPPTFSHPSYFTYIPENNPRGASIFSVTALDPDSKENAQIVYSLAEDTIEGAPLSSYISINSDTGILYALWSFDYEQFRELQVQVTASDSGKPPLHSNVSLTLFVLDQNDNSP--EILYPTMPTDGSTGVELAPRSAELGYLVTKVVAVDRDSGQNAWLSYRL-------------LKASEPGLFTVGLHTGEVRTARALMERDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 664 HSP 2 Score: 157.532 bits (397), Expect = 1.191e-38 Identity = 150/572 (26.22%), Postives = 245/572 (42.83%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDILELIANDRDDPNTK-NGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGNG--RMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNF----AISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP------SNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNL 2502
AP++ + V I E + G + + DP+ N L SYQLS K S + + + ++R I+ + A+DG R + + + D ND+ PV + + EN L V D+D+G NG + S L + D + KI + D E++S Y +EI+ D G A + K I + DVNDN+P V E++P+G+ + + DLDS NG + SI + N F +I Y + ++ DRE+ +Y VTA D G P L+ +++ DIND P F YF I E+ + + + + A D D +N + Y L + G P L + I ++ D G + + D E+ +Q+ V A D G P L + ++ + VLD NDN+P L+P S + S E+G + V D D G N +++ L+ +++ F + GE+ A + E +L L++ D GQ P + TL + S+ ++
Sbjct: 128 APKFQAETLDVKINENVAPG--MRFPLPEATDPDVGVNSLQSYQLSSN----KHFSLVVQSGAKGVKYPELVLEQALDREEEAIHHLVLVASDGGNPPRSGTVLITVTVFDANDNAPVFTSTEYRVNIPENLPVGTQLLKVTATDKDEGANGEVTYAFRKSLDTQLSKFQLDKHTGEIKISE----NLDYEEMSFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPEVTITSLFSPVTEDSPVGTVIALLNVHDLDSGQNGEVACSI-SGNLPFKLEKSIDNYYRLVTQRALDREQVPAYNITVTATDGGNPPLSTKADFTLQVADINDNPPTFSHPSYFTYIPEN---NPRGASIFSVTALDPDSKENAQIVYSLAEDTIEGAP--------LSSYISINSDTGILYALWSFDYEQFRELQVQVTASDSGKPPLHSNVSLTLFVLDQNDNSPEILYPTMPTDGSTGVELAPRSA--ELGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFTVGLH-TGEVRTARALMERD---ALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPDV 669 HSP 3 Score: 124.02 bits (310), Expect = 3.626e-28 Identity = 126/471 (26.75%), Postives = 207/471 (43.95%), Query Frame = 1
Query: 1117 RMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNL------KNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN----FAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTP-VFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPF----KIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNP-KNNIA-TLYI 2475
R+ ++I + D ND+ P K+ EN + + D D G N + L+ + +L K +++ E + + DRE+ +++ + + D GNP S ++ + D NDNAP F + ++ EN P+G+ + +V A D D NG + Y+ S D F + + GEI+ D E+ YE + A D G L + V+ + ++D+ND +P V F +TE +S + + D D GQNG V + P KL+ + N ++ A LDRE++ + + V A D G P LST ++V D+NDN P F PS F + G +I +V D D N I +SL + E P I + I+ A ++ FR L ++ + ASD G+ P +N++ TL++
Sbjct: 111 RVKLFGIEIEVTDVNDNAPKFQAETLDVKINENVAPGMRFPLPEATDPDVGVNSLQSYQLSSNKHFSLVVQSGAKGVKYP--------ELVLEQALDREEEAIHHLVLVASDGGNPPRSGTVLITVTVFDANDNAPVFTSTEYRVNIPENLPVGTQLLKVTATDKDEGANGEVTYAFRKSLDTQLSKFQLDKHTGEIKISENLDYEEMSFYEIEIQAEDGGA-YLATAKVL-ITVEDVNDNSPEVTITSLFSPVTE---DSPVGTVIALLNVHDLDSGQNGEVACSISGNLPF------KLEKSIDNYYRLVTQRA------LDREQVPAYNITVTATDGGNPPLSTKADFTLQVADINDNPPTFSHPS---YFTYIPENNPRGASIFSVTALDPDSKENAQIVYSLAE-DTIEGAPLSSYISINSDTGILYALWSFDYEQFREL--QVQVTASDSGKPPLHSNVSLTLFV 550
BLAST of Protocadherin-11 X-linked vs. Ensembl Mouse
Match: Pcdhgb5 (protocadherin gamma subfamily B, 5 [Source:MGI Symbol;Acc:MGI:1935196]) HSP 1 Score: 210.305 bits (534), Expect = 2.079e-55 Identity = 190/686 (27.70%), Postives = 317/686 (46.21%), Query Frame = 1
Query: 169 VITLNVEFSVDENCRIGHVVGNVYSKLN----QLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKL--YLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQ--TGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY---------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDIND-----CTPVFEKD--YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLD 2151
++ + + + E G VVGN+ L +LP ++ + + YFS++ SG+L+V S LDRE IC K C+++ + + + +E+ DIND+ P F T + I E+ GT + L VA+D D ++ Y ++ G F + N + + YP L + K +DRE+ + +L A D G+ +G+ + + VTD NDN P + ++ YKV + E G +L + A D+D+ N +SY Q+F +N + + I + A DG G + + +V+I I+D ND+ P I++ + + EN ++ +++ D D G NG C L+D ++ K I N YK+ T D + DRE Y V I D+G P +SS K ++++ DVNDNAP F + ++ ENNP G+++ QV A D D +NGH+ YSI+ S D S++ G + ++ FD E+ S++ + ARD+G P L+ ++ ++V + D ND P E D F + + + ++ A D D G N + Y ++ G+ LR G + L ++ + +LLV D G P LS T T+++ D
Sbjct: 28 ALSEQIRYKIPEEMPTGSVVGNLAKDLGFSVQELPTRK----LRISSEKPYFSVSSESGELLVSSRLDREQIC-GKKLVCALEFEAVAENPLNFYHVSVELEDINDHTPNFTHTFSELQISESAQPGTRFILEVAEDADIALNSLQNYKLSPSPG----------------FSLVNKEKQDGRKYPELVLEKTLDREQQNYYRLVLTALDGGDPPLSGTTELRIQVTDANDNPPVFNQEVYKVRLPENVPPGTTVLRVTATDKDE--GVNSEISYSFHR-------AGQVFGLNSKSGEIITQKTLDFEEIKEYSIVVEARDGGGLVAQCTVEINIQDENDNRPEITVRSLLEMIPENAPPGTLIALIKIHDGDSGENGEVNCRLDD--EVPFKIISSSKNS--YKLVT--DRALDRELTPEYNVTITATDRGKPPLSSSTKVTLHVGDVNDNAPLFHQASYLVYIAENNPPGASIAQVSASDPDLGSNGHVSYSIIAS-DLEPKSLWSYVTVNAQSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRNDNAPRVLYPALEPDGSALFDMVPRAAQ--PGYLVTKVVAVDADSGHNAWLSYHVLQASDPGL-----FSLGLRT-------GEVRTARALGEKDAARQRLLVGVRDGGQPPLSATATLLLVFAD 662 HSP 2 Score: 161.77 bits (408), Expect = 6.055e-40 Identity = 139/498 (27.91%), Postives = 224/498 (44.98%), Query Frame = 1
Query: 1072 RNNIRIYITATDGNGR--MNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHI--------VYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITE--SYGESIKNERLEQIKATDKDLGQNGTVKYRLI--DVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPS----NNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNP 2508
+N R+ +TA DG T + I + D ND+PPV + ++ EN + V D+D+G N S + +G++ F N +I T + D E+I Y++ ++ D G + + INI D NDN P + + + EN P G+ + ++ D DS NG + + I++S+ N ++ + DRE T Y +TA D G+P L+ S V + + D+ND P+F + Y I E G SI Q+ A+D DLG NG V Y +I D++P + + A+ G + D E++ S QL +QA D G P+LS ++ + V D NDNAP L+P+ + F V + G + V D D G N +++ ++ ++ F ++ GE+ A + E R RL++ D GQ P + ATL + + SL P
Sbjct: 205 QNYYRLVLTALDGGDPPLSGTTELRIQVTDANDNPPVFNQEVYKVRLPENVPPGTTVLRVTATDKDEGVNSEISYSFHRAGQV------FGLNSKSGEIIT--QKTLDFEEIKEYSIVVEARDGG--GLVAQCTVEINIQDENDNRPEITVRSLLEMIPENAPPGTLIALIKIHDGDSGENGEVNCRLDDEVPFKIISSSKNSY-----KLVTDRALDRELTPEYNVTITATDRGKPPLSSSTKVTLHVGDVNDNAPLFHQASYLVYIAENNPPGASIA-----QVSASDPDLGSNGHVSYSIIASDLEPKSLWSYVTVNAQ---------SGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRNDNAPRVLYPALEPDGSALFDMVPRAAQPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLR-TGEVRTARALGEKDAAR---QRLLVGVRDGGQPPLSATATLLLVFADSLQEALP 669 HSP 3 Score: 70.8626 bits (172), Expect = 8.193e-12 Identity = 92/325 (28.31%), Postives = 141/325 (43.38%), Query Frame = 1
Query: 1504 PRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY---GEIQSKIKFDREKTDSYEFVVTARDNG--EPQLNDSMVVKVKIQDINDCTPVFEKDYF-FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEI--GKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM-----KEFSNFRSLPDRLIIKASDLG 2439
P +I+ + + E P GS VG + A DL S + S++ S+ GE+ + DRE+ + V E LN V V+++DIND TP F + +I+ES + R A D D+ N Y+L PG S + E ++ K + + LDRE+ + +L++ A D G P LS TT + I+V D NDN PVF N V + + G T+ V D D+G+N I++S + + K GEII T+ KE+S ++++A D G
Sbjct: 27 PALSEQIR-YKIPEEMPTGSVVGNL-AKDLGFSVQELPTRKLRISSEKPYFSVSSESGELLVSSRLDREQICGKKLVCALEFEAVAENPLN-FYHVSVELEDINDHTPNFTHTFSELQISES---AQPGTRFILEVAEDADIALNSLQNYKLSPS-----PGFSLVNKEKQDGRKYP---ELVLEKTLDREQQNYYRLVLTALDGGDPPLSGTTELRIQVTDANDNPPVF-----NQEVYKVRLPENVPPGTTVLRVTATDKDEGVNSEISYSFHRAGQVFGLNSK---SGEIITQKTLDFEEIKEYS--------IVVEARDGG 321
BLAST of Protocadherin-11 X-linked vs. UniProt/SwissProt
Match: sp|Q08174|PCDH1_HUMAN (Protocadherin-1 OS=Homo sapiens OX=9606 GN=PCDH1 PE=1 SV=2) HSP 1 Score: 226.868 bits (577), Expect = 1.659e-59 Identity = 199/699 (28.47%), Postives = 315/699 (45.06%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNI---RIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIR--FDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNL--DREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM-KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTN 2499
F + + I EN IG+ +P+P+A D+D+ GV +Y E Q Q+ QEE P L ++ N+DRE + S+ + D G+ + S + V V D NDNAP++ + +Y+ + E G ++++ AND D N + Y E +V ++ ++ N +T + G ++R ++ R + A D N + V + ++D ND+ P I I + + E+ ++ + VQV D D+G N C + L+ D+ Y ++T T D EK+ YT+EI VD GNP +SS + ++DVNDNAP F + ENN G + ++ A D DS +N +VYS+ + F IS GEIQ K DRE+ +SYE V A D G P L + V V + D ND P F Y F + E+ + + D D G+N V +L E N V +G ++ +L DRE+ S+ ++A D G P S + I VLD NDNAP PSN + + ++ + +G+T+ V +D D G+N + +S+ N P+ + G A T+ KE RL++K SD G+ P+ A +++ +L N
Sbjct: 168 FASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY----------ELQAGPEAQELFGLQVAE---DQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSD--QGANAEIEYTFHQAPE---VVRRLLRLDRNTGLIT---VQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTT--TPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENM---PALSPVGMVTVIDGDKGENAQV----------------QLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL-LTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGN-----PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLAN 818 HSP 2 Score: 106.686 bits (265), Expect = 6.215e-22 Identity = 88/337 (26.11%), Postives = 148/337 (43.92%), Query Frame = 1
Query: 1375 DTSFDREKIS-----------VYTVEIKCVD---QGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISIYGEIQSKIK-------FDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFL-----FPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTIT 2292
+TS DRE + + E+ D G+P + Q I + D+NDN P F + + + EN IGS A D D+ NG Y + + + F + + + + K DRE+ DSY+ + +D G P S +++V + D ND P FE+ Y ++E+ S + Q+KA D D G N ++Y + +R L+++ + G I+V G +DRE++S+++ V A D G S +++ V D+NDNAP ++ N+S + + V+ D D+G N +T
Sbjct: 112 ETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSEN---SPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV-----------VRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVT 431
BLAST of Protocadherin-11 X-linked vs. UniProt/SwissProt
Match: sp|Q5DRB6|PCDG4_PANTR (Protocadherin gamma-A4 OS=Pan troglodytes OX=9598 GN=PCDHGA4 PE=3 SV=1) HSP 1 Score: 203.756 bits (517), Expect = 1.890e-52 Identity = 192/697 (27.55%), Postives = 324/697 (46.48%), Query Frame = 1
Query: 136 LDILIIFSIKLVITL-NVEFSVDENCRIGHVVGNVYSKLNQLPN--SSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCS-MKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNF---AISIYGEIQSKI-------KFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDIND-----CTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLD 2151
L I ++ + + I + +SV E G VVGN+ L P + R + + + F+LN SG L+ +DRE +C+ + + +++ L+ +++ +EI D+NDN P F T Q+ I + EN GT +PLP A D D ++ Y + N+ +F + YP L + + +DREE +L A D G+ ++G+ + +++ D NDNAP +T+ Y V++ E G +L + A D D+ NG V+Y + R +SQ+F +N +T I G ++ + Y + A DG G + V + + D ND+ P +++ + V E ++ V D D G NG+ CS+ D+ L+ N+ Y++ T+ + DRE++S Y + + DQG P +S+ S+ ++D+NDN P F + +V ENNP G+++ + A D DS +N I YS+ + D F +S Y I S FD E+ + +VTA D+G+P L+ ++ + + + D ND P F D + + + + ++ A D+D GQN + YRL+ G+ E+R + LDR+ + L+V D G P LS T T+ + V D
Sbjct: 14 LHICLLLGVLVEIRAEQIRYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPGTRFPLPEAFDPDVGVNSLQGYQL----------------NSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVHENVPVGTLLLTVKATDPDE--GANGDVTYSFR---KVRDKISQLFQLNSLSGDIT---ILGDLDYEDSGFYDIDVEAHDGPGLRARSKVLVTVLDENDNAPEVTVTSLTSSVQETSSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTY--GNY--YRLLTH--RTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYVPENNPRGASILSMTAQDPDSGDNARITYSL--AEDTFQGAPLSSYVSINSNTGILYALRSFDYEQFRDLQLLVTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPTFPTDDSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYRLLKSSEPGLFAVGLHTGEVRTARAL-----------LDRDALKQ-SLVVVVQDHGQPPLSATVTLTVAVAD 666 HSP 2 Score: 140.198 bits (352), Expect = 2.558e-32 Identity = 160/563 (28.42%), Postives = 234/563 (41.56%), Query Frame = 1
Query: 847 EWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVS----QIFYINGNKLHL-TNNRI--SGLINRN-----NIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-----SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGE-SIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVF-------LFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPF----KIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNP 2448
E + + ++ E Q EG ++ IA D GL +L++R +IVS Q+F +N L T RI L +R+ N+ I + T + V++ I D ND+PP R KV EN+ + D D G N + LN +G +L D I E + + DRE+ +V+ + + D G+P S + I ++D NDNAP F V EN P+G+ + V+A D D NG + YS D + S+ G+I D E + Y+ V A D P L V V + D ND P + +T S E S + D D G NG V + D P L+ N + + + LDREE+S + V A D G P LST T I ++V+D+NDN P F P NN G +I ++ +D D G N IT+SL + + P I I+ A ++ FR L +L++ ASD G P
Sbjct: 25 EIRAEQIRYSVFEEQEEGSVVGNIAKDL-------GLAPRELAER--GVRIVSRGRTQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDT-----VKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPGTRFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGAD--GIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVHENVPVGTLLLTVKATDPDEGANGDVTYSFRKVRDKISQLFQLNSLSGDITILGDLDYEDSGFYDIDVEAHDG--PGLRARSKVLVTVLDENDNAP---EVTVTSLTSSVQETSSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPF------TLEKTYGNYYR------LLTHRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYVPENNPR----------GASILSMTAQDPDSGDNARITYSLAE-DTFQGAPLSSYVSINSNTGILYALRSFDYEQFRDL--QLLVTASDSGDPP 541 HSP 3 Score: 134.42 bits (337), Expect = 1.702e-30 Identity = 133/512 (25.98%), Postives = 215/512 (41.99%), Query Frame = 1
Query: 1084 RIYITATDGNG--RMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLND-----SGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI------YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFL---FPSNNMNFVNVSVE-WEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSIGKKSHSSDNNNFGFRL 2565
+ +TA DG R + I + D ND+ PV + V EN +L TV+ D D+G NG S S L ++ D I Y D+ F Y ++++ D P + + K + ++D NDNAP V E + G+ + D DS NG + SI DN ++ Y + + DRE+ Y VTA D G P L+ + +++ DIND P F Y + E+ + + + + A D D G N + Y L + G P +S + S G + + D E+ +QLLV A D G P LS+ ++ + VLD NDN P L FP+++ V ++ + G + V D D G N +++ L+ S++ F + GE+ T + + +L L++ D GQ P + TL + S+ ++ +G S+D ++ G L
Sbjct: 209 HLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVHENVPVGTLLLTVKATDPDEGANGDVTYSFRKVRDKISQLFQLNSLSGD--ITILGDLDYEDSGF-------YDIDVEAHD--GPGLRARSKVLVTVLDENDNAPEVTVTSLTSSVQETSSPGTVIALFNVHDSDSGGNGLVTCSI---PDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYVPEN---NPRGASILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVSIN-------SNTGILYALRSFDYEQFRDLQLLVTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPTFPTDDSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYRLLKSSEPGLFAVGLH-TGEV---RTARALLDRDALKQSLVVVVQDHGQPPLSATVTLTVAVADSIPDVL-ADLGSLKPSADPDDSGLTL 691
BLAST of Protocadherin-11 X-linked vs. UniProt/SwissProt
Match: sp|Q5DRA6|PCDGI_PANTR (Protocadherin gamma-B6 OS=Pan troglodytes OX=9598 GN=PCDHGB6 PE=3 SV=1) HSP 1 Score: 202.986 bits (515), Expect = 3.123e-52 Identity = 194/706 (27.48%), Postives = 320/706 (45.33%), Query Frame = 1
Query: 184 VEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKL--YLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETY-----PDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAISIY-------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-------EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTI-------IIEVL-DLNDNAPVFLFPSNNMNF 2202
+ +S+ E G VVGN+ L + ++ + + +FS++ SGDL+VK+ +DRE IC+ + C ++L ++ + +++ I D+ND+ P F + + I E+ GT L A D D +K Y I N+ +F + + YP L + K +DREE S IL A D G+ ++ + + + V D NDN P +++D Y++++ E G +L++ A D+D+ N ++Y + K +F ++ + NN+ + + + A DG G + V I I D ND+ P I I + ++LEN +++ + +D D G NG C NI D F IY + D + DRE+ Y V I D+G P +SS + ++ + D+NDNAP F + HV ENNP G+++ QV A D D NGHI YSI+ S+ + A+S Y G + ++ FD E+ ++ + ARD+G P L+ ++ ++V + D ND P + FF + E + ++ A D D G N + Y ++ G+ LR G + L + + +LLV D G P LS T T+ + E+L DL+D PV P + F
Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSAEKLHFSVDAESGDLLVKNRIDREQICKERRR-CELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI----------------NSNPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRISLSENLPPGSPVLQVTATDQDE--GVNAEINYYFRSTAQSTK---HMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGGGLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPGMVVALFKTRDLDFGGNGEVRC-----------NIETDIPFKIYSSSNHYYKLVTDGALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAE--PGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL-----FSLGLRT-------GEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADNLQEILPDLSDR-PVLSDPQAELQF 690 HSP 2 Score: 95.1301 bits (235), Expect = 2.257e-18 Identity = 88/297 (29.63%), Postives = 137/297 (46.13%), Query Frame = 1
Query: 1474 INIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI--------YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI 2340
+ I DVND+AP+F K + E+ G+ + A D D + N Y I NSN F++ + Y E+ + DRE+ S+ ++TA D G+P + + +++ ++D ND PVF +D + RI+ S + L Q+ ATD+D G N + Y S ++ G I + D E++ + V+A D G LST +IIE+LD NDN+P + S + + S G + KT+DLD G NG + N + PFKI
Sbjct: 121 VVIEDVNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI-NSNPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEY-RISLSENLPPGSPVL-QVTATDQDEGVNAEINYYF----------RSTAQSTKHMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPP---GMVVALFKTRDLDFGGNGE-----VRCNIETDIPFKI 394
BLAST of Protocadherin-11 X-linked vs. UniProt/SwissProt
Match: sp|Q5DRA9|PCDGE_PANTR (Protocadherin gamma-B2 OS=Pan troglodytes OX=9598 GN=PCDHGB2 PE=3 SV=1) HSP 1 Score: 202.986 bits (515), Expect = 3.793e-52 Identity = 188/679 (27.69%), Postives = 309/679 (45.51%), Query Frame = 1
Query: 169 VITLNVEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXX------XXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-------DNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-------EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTI 2133
+ + + +S+ E VVGN+ L + ++ + + YF++N SGDL+V +DRE IC + C LD DT A + + DINDN P+F+ T+ + I E+ GTT+PL A D D ++ Y++ N+ ++F + ++ YP L + ++DREE +L A D G+ Q+G+ + V VTD NDN P +++D Y+V ++E G +L++ A DRD+ N ++Y + E V F +N +T ++ + I A D S+ + I D ND P + + + F + E+ ++ ++ +D D G NG C + + K LK+ N+ YK+ T D + DRE+I Y + I D G P +SS +++I DVNDNAP F M HV ENNP G+++ Q+ A D D NG + YSI+ S+ ++S G + ++ FD E+ ++E + ARD G P L+ ++ ++V + D+ND P + F + E + ++ A D D G N + Y ++ G+ LR G + L + + +LLV D G P LS T T+
Sbjct: 28 ALPVQIRYSIPEELAKNSVVGNLAKDLGLSVRDLPARKLRVSAEKEYFTVNPESGDLLVSDRIDREQIC-GKQPLC----VLDFDTVAENPLNIFYIAVIVQDINDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHL----------------NDNEYFDLAEKQTPDGRKYPELILQHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRVKVTDANDNPPVFSQDVYRVTLREDVPPGFFVLQVTATDRDE--GVNAEITYSFHNVDEQ---VKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAKDPGDLAAHCSIQVEILDDNDCAPEVIVTSVFTPLPEDSPPGTVIALIKTRDRDSGENGEVYCQVLGNAKFILKS--SSKNY--YKLVT--DGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQISASDPDLGPNGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGSDGSALFDMVPRAAE--PGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL-----FSLGLRT-------GEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATL 660 HSP 2 Score: 173.326 bits (438), Expect = 1.039e-42 Identity = 139/491 (28.31%), Postives = 232/491 (47.25%), Query Frame = 1
Query: 1084 RIYITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI----YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITE--SYGESIKNERLEQIKATDKDLGQNGTVKYRLI--DVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPS----NNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNP 2508
++ +TA DG + T + + + D ND+PPV S + E+ + V D D+G N S ++ + +K+ F+ N +I T D F E S YT+ I+ D G+ +++ + I+D ND AP + + E++P G+ + ++ D DS NG + +L N F + Y ++ + DRE+ Y +TA D G+P L+ S++V + I D+ND PVF++ Y + E G SI QI A+D DLG NG V Y ++ D+KP E+ + + VS G + D E++ + +L +QA D G P+LS ++ + V DLNDNAP L+P+ + F V E G + V D D G N +++ ++ +++ F ++ GE+ A + + R RL++ D GQ P + ATL++ + SL + P
Sbjct: 209 QLVLTAVDGGDPPQSGTTQIRVKVTDANDNPPVFSQDVYRVTLREDVPPGFFVLQVTATDRDEGVNAEITYSFHNVDE-QVKHF-FNLNEKTGEITTKDDLDF--EIASSYTLSIEAKDPGD--LAAHCSIQVEILDDNDCAPEVIVTSVFTPLPEDSPPGTVIALIKTRDRDSGENGEVYCQVLG-NAKFILKSSSKNYYKLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIA-----QISASDPDLGPNGQVSYSIVASDLKP----------REILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGSDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLR-TGEVRTARALGDRDAARQ---RLLVAVRDGGQPPLSATATLHLIFADSLQEVLP 673 HSP 3 Score: 152.91 bits (385), Expect = 2.447e-36 Identity = 129/450 (28.67%), Postives = 201/450 (44.67%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDT----SFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI-----YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTP-VFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSK--LKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSN--KRENFPF-KIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLG 2439
+ + ++D ND+ P+ K+ E+ K D D G N + LND+ +L + D YP+ S DRE+ S++ + + VD G+P S + + + D NDN P F + + E+ P G V QV A D D N I YS N ++ GEI +K D E SY + A+D G+ L ++V+I D NDC P V F + E +S + IK D+D G+NG V +++ GN+K LK+ +N K+ DGA LDREEI L + A D G P LS++ + + + D+NDNAPVF V+V+ G +I + D D G NG +++S++ S+ RE + + + ++ A + R+ L ++A D G
Sbjct: 119 IAVIVQDINDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYFDLAEKQTPDG------RKYPELILQHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRVKVTDANDNPPVFSQDVYRVTLREDVPPGFFVLQVTATDRDEGVNAEITYSFHNVDEQVKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAKDPGD--LAAHCSIQVEILDDNDCAPEVIVTSVFTPLPE---DSPPGTVIALIKTRDRDSGENGEVYCQVL--------GNAKFILKSSSKNYYKLVTDGA------LDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPVF---QQTSYMVHVAENNPPGASIAQISASDPDLGPNGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAF--ELTLQARDQG 538
BLAST of Protocadherin-11 X-linked vs. UniProt/SwissProt
Match: sp|Q9Y5F9|PCDGI_HUMAN (Protocadherin gamma-B6 OS=Homo sapiens OX=9606 GN=PCDHGB6 PE=2 SV=1) HSP 1 Score: 202.601 bits (514), Expect = 5.149e-52 Identity = 196/708 (27.68%), Postives = 322/708 (45.48%), Query Frame = 1
Query: 184 VEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKL--YLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIY-------KIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAISIY-------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-------EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTI-------IIEVL-DLNDNAPVFLFPSNNMNF 2202
+ +S+ E G VVGN+ L + ++ + + +FS++ SGDL+VK+ +DRE IC+ + C ++L ++ + +++ I D+ND+ P F + + I E+ GT L A D D +K Y I N+ +F + + YP L + K +DREE S IL A D G+ ++ + + + V D NDN P +++D Y++++ E G +L++ A D+D+ N ++Y + K +F ++ + NN+ + + + A DG G + V I I D ND+ P I I + ++LEN +++ + +D D G NG C NI D F IY K+ T D + DRE+ Y V I D+G P +SS + ++ + D+NDNAP F + HV ENNP G+++ QV A D D NGHI YSI+ S+ + A+S Y G + ++ FD E+ ++ + ARD+G P L+ ++ ++V + D ND P + FF + E + ++ A D D G N + Y ++ G+ LR G + L + + +LLV D G P LS T T+ + E+L DL+D PV P + F
Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSAEKLHFSVDAESGDLLVKNRIDREQICKERRR-CELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI----------------NSNPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRISLSENLPPGSPVLQVTATDQDE--GVNAEINYYFRSTAQSTK---HMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGGGLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPGMVVALFKTRDLDFGGNGEVRC-----------NIETDIPFKIYSSSNNYYKLVT--DGALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAE--PGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL-----FSLGLRT-------GEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADNLQEILPDLSDR-PVLSDPQAELQF 690 HSP 2 Score: 94.7449 bits (234), Expect = 2.817e-18 Identity = 88/295 (29.83%), Postives = 136/295 (46.10%), Query Frame = 1
Query: 1480 IIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI--------YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI 2340
I DVND+AP+F K + E+ G+ + A D D + N Y I NSN F++ + Y E+ + DRE+ S+ ++TA D G+P + + +++ ++D ND PVF +D + RI+ S + L Q+ ATD+D G N + Y S ++ G I + D E++ + V+A D G LST +IIE+LD NDN+P + S + + S G + KT+DLD G NG + N + PFKI
Sbjct: 123 IEDVNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI-NSNPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEY-RISLSENLPPGSPVL-QVTATDQDEGVNAEINYYF----------RSTAQSTKHMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPP---GMVVALFKTRDLDFGGNGE-----VRCNIETDIPFKI 394
BLAST of Protocadherin-11 X-linked vs. TrEMBL
Match: A0A4E0S0C6 (Uncharacterized protein OS=Fasciola hepatica OX=6192 GN=D915_000360 PE=4 SV=1) HSP 1 Score: 336.65 bits (862), Expect = 1.050e-92 Identity = 255/845 (30.18%), Postives = 398/845 (47.10%), Query Frame = 1
Query: 499 VINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIA-----------------RCQ-GIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFV-SFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWT-----------------------------KDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDR--KIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVL--ENQKQKIILTTVQVKDED--KGRNGMFECSLNDSGKLNLKNI----RFDDN----------------------------FAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIK---------------------MFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN-----------------FAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQ-LNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRL-IDVKPIGIPGNSKLKAEL----RNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYP-SLSTTTTIIIEVLDLNDNAPVFLFP-------------------------------SNNMNF-VNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKREN----------FPFKIQPEGEIIIAHTMKEFSNFRS-----------LPDRLIIKASDLGQNPKNNIATLYIRY 2481
VI + E PIGT LP A D D+ ++GV+ Y R Q G+ E+ Q +P+ + P L I+ +DRE F F LIATD + G V +LV DVND+APEW + +Y ++ EC ++ ++ L A D+DDP G ++++LS+ + DR + + +++ + L+LT+ + GL + N+ I + A+DG GR E + IEDCNDH P+I I N + E+ Q +++ + V+D D N F C LND+ L LK + DD +++Y++ + + SFDRE ++YTV +C+D+G+P++++ + +I+I D+NDNAP+F+ + +F V E+ G +G VRA+DLDS N + Y++L+ ++N F ++ GE+ + DRE YEF+V A D+G+ Q L+ + V++ + D+NDC PVF DY F + ESYG S ++ L + ATD DLG+NG+V YRL + + G+ G SK ++ L+KVS DG I+VYG +DRE+I+ I + V A D+G P +ST TT+ I VLDLNDN P F+ P S++ + +N+S++ IG I + D D G NGT+T LI S F F + P+G +I+ + + EF + PD L+I+ SD G P++ I + I Y
Sbjct: 208 VITVDEECPIGTMIQLPQATDPDTQEHGVQRYEFHPTSTAVRVREHFDVVQFRHQPGLRCEDVTSVQLEMIQSVAPADPR----PVVPCLRTIRRLDRETAGDQFHFNLIATDTNGKRGEIAVQLLVRDVNDHAPEWATKLELFDSSSRSHWISASPSDPAHGTESRQTHYTFSVPECTTQHKLIRLEAQDKDDPQQDGGKITFRLSEHSPDRLPTTLRRRLFVSNDHLYLTDRGLRGLA-QPNLTIVVVASDGAGRNTEAWFHLRIEDCNDHRPMILIQNTDYITIPEESAGQSHLVSLITVRDFDLVTSPNSQFSCFLNDTTYLELKEVVAGPTADDRDLLHSHSHQGDEITSTGGKEDLSSRRGRWSVYRLGSRSEISFDRETSALYTVMFECIDKGSPSLTASRPITIHIEDINDNAPQFITRCAPLPLSQNTKDIKPNRPCTPQFVFTVSEDAERGILIGSVRAVDLDSGENARVEYTLLSLHNNSTVPDSNESEVFRPETLFTVTPMGELHLLGELDRESQSYYEFLVVATDHGKRQRLSSTATVQITVADVNDCAPVFRGDYVFEVVESYGSSTIHQVLGTLNATDADLGRNGSVHYRLAVHPRESGLSGLSKSMSDSAVPGAQLVKVSHDGQITVYGVVDREQITMIMVDVIAEDNGVPLHMSTMTTVTIHVLDLNDNKPRFVQPEFTAGRLPSSFSNQKPERFNTLGLPPSFEALSSDATYKLNLSLDTSIGTLITKFEAFDPDYGPNGTLTFELIYSGGTMQTRSDPGNSSLFTFTLHPDGRLILTNHL-EFDTVYTGSTRLVPRRYRRPDHLLIRVSDQGSTPEHVITGVQIIY 1046
BLAST of Protocadherin-11 X-linked vs. TrEMBL
Match: A0A1I8H4K2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 249.98 bits (637), Expect = 1.255e-64 Identity = 239/818 (29.22%), Postives = 379/818 (46.33%), Query Frame = 1
Query: 142 ILIIFSIKLVITLN----VEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXX------XXXXXFQTTQK--VINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATD--FGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQS-EGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLN--DSGKLNLKNIRFDDNF-AIYKIETYPDTSFDREKIS--VYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL-NSNDNFAISIYG----EIQSKIKFDREKTDSYEFVVTARDNG-EPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNL----IKVSFDGA-ISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMK---EFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIH 2487
I ++ I L ++ + V F E IG+ +GN+ ++ + S + L +E F L+ +G L + LDRE +C N C ++ I D P F+ K I+I E+ + Y LP A+D DS +Y Y +K IG+ +F++ + + + P LE+ K +DRE ++ L+ +D S + + V D NDN P+W + I EC +L+L A D D N ++Y + K V++ FYI+G+KL + I + + I + A D G ET V++ + DCNDH P I++ K+LEN + + +L + V DED+G NG +C + + K L N D + IYK++ SFDRE S V+I C D+G+ ++ I I+D NDNAPR +K+ F + EN+P + VG+V A D D N + +S+ + + NF I G EI S + FDRE+ D Y F VT D+G + Q + V+V I D +D P F+ ++Y FRI E YG ++ + ++KATD D+G N + Y + N + +A L ++ + F+G+ + GN DRE+ I L + A + G + + I + D+NDNAP N+S G + V DLD G NGT+T+ L ++ E F I + G + ++ ++K F+S RL I D G P ++I Y ++H
Sbjct: 9 ISTLWPILLAVSQDSQPTVTFYTKEEIPIGNEIGNLKTRFSYPDGSQFNMLFPDSEIRRLFRLDSRTGALSTIARLDREVLCPNKPLECLRTFNVEVKRGGTGQEEVIVIRLIINDVNDQRPKFEAKHKKFRISIPESDNPPSYYSLPTAEDGDSDRYDHVKY------------DLKMIGDAGMYFKLFLEERGSKRV-PKLELTKALDRETKDNYELQLLVSDEQHPQDQDSADIQIEVLDANDNKPQWRLAKQSITISECDRLHRPLLKLNATDED----LNERITYSIGKAAG--KDVAKSFYISGDKLKQNQSLDYEKIRKKVLYIPLVAEDRGGSTVETYVELRVTDCNDHYPNITVEMIEDKILENDETEKVLARILVVDEDEGNNGTVDCVIGVPNKRKFQLTNRITDGQYKTIYKLKKLAHVSFDREATSGGEVRVDIICTDKGDSPRVGRKEVKIMILDENDNAPRIESKLYTFRIHENSPPNTLVGRVTARDDDIDENARLKFSLHSDGSRNFVIRNQGNNMAEIYSAVSFDREQIDHYRFTVTVADSGLKEQRTSTATVEVTIVDEDDSVPTFQFREYMFRIEEDYGRNLSKRYIGEVKATDADIGANQMIWYEV----------NRQYQASLADVGISGMYFYFNGSHLYGEGNFDREKQEIINLEIFARNRGPAKHKGSARVTITLNDVNDNAPSI---QGLQKVYNLSENSPAGTPVLQVSGTDLDAGENGTLTYIL---DETEANRFTIDGKHGIVTLSGSLKNNQPEDGFQSQTYRLGIGVRDNGNPPLHSIK--YTTFVH 789
BLAST of Protocadherin-11 X-linked vs. TrEMBL
Match: A0A267GLZ2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017053g2 PE=4 SV=1) HSP 1 Score: 249.98 bits (637), Expect = 1.257e-64 Identity = 240/818 (29.34%), Postives = 380/818 (46.45%), Query Frame = 1
Query: 142 ILIIFSIKLVITLN----VEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXX------XXXXXFQTTQK--VINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTG--SCXXXXXXXXXXXXAPEWTKDNYKVNIQECQS-EGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLN--DSGKLNLKNIRFDDNF-AIYKIETYPDTSFDREKISV--YTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL-NSNDNFAISIYG----EIQSKIKFDREKTDSYEFVVTARDNG-EPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNL----IKVSFDGA-ISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMK---EFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIH 2487
I ++ I L ++ + V F E IG+ +GN+ ++ + S + L +E F L+ +G L + LDRE +C N C ++ I D P F+ K I+I E+ + Y LP A+D DS +Y Y +K IG+ F++ + + + P LE+ K +DRE ++ L+ +D +Q S + + V D NDN P+W + I EC +L+L A D D N ++Y + K V++ FYI+G+KL + I + + I + A D G ET V++ + DCNDH P I++ K+LEN + + +L + V DED+G NG +C + + K L N D + IYK++ SFDRE S V+I C D+G+ ++ I I+D NDNAPR +K+ F + EN+P + VG+V A D D N + +S+ + + NF I G EI S + FDRE+ D Y F VT D+G + Q + V+V I D +D P F+ ++Y FRI E YG ++ + ++KATD D+G N + Y + N + +A L ++ + F+G+ + GN DRE+ I L + A + G + + I + D+NDNAP N+S G + V DLD G NGT+T+ L ++ E F I + G + ++ ++K F+S RL I D G P ++I Y ++H
Sbjct: 9 ISTLWPILLAVSQDSQPTVTFYTKEEIPIGNEIGNLKTRFSYPDGSQFNMLFPDSEIRRLFRLDSRTGALSTIARLDREVLCPNKPLECLRTFNVEVKRGGTGQEEVIVIRLIINDVNDQRPKFEAKHKKFRISIPESDNPPSYYSLPTAEDGDSDRYDHVKY------------DLKMIGDAGMHFKLFLEERGSKRV-PKLELTKALDRETKDNYELQLLVSDEQHQQDQDSADIQIEVLDANDNKPQWRLAKQSITISECDRLHRPLLKLNATDED----LNERITYSIGKAAG--KDVAKSFYISGDKLKQNQSLDYEKIRKKVLYIPLVAEDRGGSTVETYVELRVTDCNDHYPNITVEMIEDKILENDETEKVLARILVVDEDEGNNGTVDCVIGVPNKRKFQLTNRITDGQYKTIYKLKKLAHVSFDREATSGGDVRVDIICTDKGDSPRVGRKEVKIMILDENDNAPRIESKLYTFRIHENSPPNTLVGRVTARDDDIDENARLKFSLHGDGSRNFVIRNQGNNMAEIYSAVSFDREQIDHYRFTVTVADSGLKEQRTSTATVEVTIVDEDDSVPTFQFREYMFRIEEDYGRNLSKRYIGEVKATDADIGANQMIWYEV----------NRQYQASLADVGISGMYFYFNGSHLYGEGNFDREKQEIINLEIFARNRGPAKHKGSARVTITLNDVNDNAPSI---QGLQKVYNLSENSPAGTPVLQVSGTDLDAGENGTLTYIL---DETEANRFTIDGKHGIVTLSGSLKNNQPEDGFQSQTYRLGIGVCDNGNPPLHSIK--YTTFVH 789
BLAST of Protocadherin-11 X-linked vs. TrEMBL
Match: A0A267DHT6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017053g3 PE=4 SV=1) HSP 1 Score: 249.98 bits (637), Expect = 1.456e-64 Identity = 240/818 (29.34%), Postives = 378/818 (46.21%), Query Frame = 1
Query: 142 ILIIFSIKLVITLN----VEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXX------XXXXXFQTTQK--VINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATD--FGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQS-EGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLN--DSGKLNLKNIRFDDNF-AIYKIETYPDTSFDREKIS--VYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL-NSNDNFAISIYG----EIQSKIKFDREKTDSYEFVVTARDNG-EPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNL----IKVSFDGA-ISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMK---EFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIH 2487
I ++ I L ++ + V F E IG+ +GN+ ++ + S + L E F L +G L + LDRE +C N C ++ I D P F+ K I+I E+ + Y LP A+D DS +Y Y +K IG+ +F++ + + + P LE+IK +DRE ++ L+ +D S + + V D NDN P+W + I EC +L+L A D D N ++Y + K V++ FYI+G+KL + I + + I + A D G ET V++ + DCNDH P I++ K+LEN + + +L + V DED+G NG +C + + K L N D + IYK++ SFDRE S V+I C D+G+ ++ I I+D NDNAPR +K+ F + EN+P + VG+V A D D N + +S+ + + NF I G EI S + FDRE+ D Y F VT D+G + Q + V+V I D +D P F+ ++Y FRI E YG ++ + ++KATD D+G N + Y + N + +A L ++ + F+G+ + GN DRE+ I L + A + G + + I + D+NDNAP N+S G + V DLD G NGT+T+ L ++ E F I + G + ++ ++K F+S RL I D G P ++I Y ++H
Sbjct: 9 ISTLWPILLAVSQDSQPTVTFYTKEEIPIGNEIGNLKTRFSYPDGSQFNMLFPDPEIRRLFRLESRTGALSTIARLDREVLCPNKPLECLRTFNVEVKRGGTGQEEVIVIRLIINDVNDQRPKFEAKHKKFRISIPESDNPPSYYSLPTAEDGDSDRYDNVKY------------DLKMIGDAGMYFKLFLEERGSKRV-PKLELIKALDRETKDNYELQLLVSDEQHPQDQDSADIQIEVLDANDNKPQWRLAKQSITISECDRLHRPLLKLNATDED----LNERITYSIGKAAG--KDVAKSFYISGDKLKQNQSLDYEKIRKKVLYIPLVAEDRGGSTVETYVELRVTDCNDHYPNITVEMIEDKILENDETEKVLARILVVDEDEGNNGTVDCVIGVPNKRKFQLTNRITDGQYKTIYKLKKLAHVSFDREATSGGEVRVDIICTDKGDSPRVGRKEVKIMILDENDNAPRIESKLYTFRIHENSPPNTLVGRVTARDDDIDENARLKFSLHSDGSRNFVIRNQGNNMAEIYSAVSFDREQIDHYRFTVTVADSGLKEQRTSTATVEVTIVDEDDSVPTFQFREYMFRIEEDYGRNLSKRYIGEVKATDADIGANQMIWYEV----------NRQYQASLADVGISGMYFYFNGSHLYGEGNFDREKQEIINLEIFARNRGPAKHKGSARVTITLNDVNDNAPSI---QGLQKVYNLSENSPAGTPVLQVSGTDLDAGENGTLTYIL---DETEANRFTIDGKHGIVTLSGSLKNNQPEDGFQSQTYRLGIGVRDNGNPPLHSIK--YTTFVH 789
BLAST of Protocadherin-11 X-linked vs. TrEMBL
Match: A0A267GS00 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017053g1 PE=4 SV=1) HSP 1 Score: 249.21 bits (635), Expect = 2.431e-64 Identity = 236/800 (29.50%), Postives = 371/800 (46.38%), Query Frame = 1
Query: 184 VEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXX------XXXXXFQTTQK--VINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATD--FGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQS-EGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLN--DSGKLNLKNIRFDDNF-AIYKIETYPDTSFDREKIS--VYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL-NSNDNFAISIYG----EIQSKIKFDREKTDSYEFVVTARDNG-EPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNL----IKVSFDGA-ISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMK---EFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIH 2487
V F E IG+ +GN+ ++ + S + L +E F L+ +G L + LDRE +C N C ++ I D P F+ K I+I E+ + Y LP A+D DS +Y Y +K IG+ +F++ + + + P LE+ K +DRE ++ L+ +D S + + V D NDN P+W + I EC +L+L A D D N ++Y + K V++ FYI+G+KL + I + + I + A D G ET V++ + DCNDH P I++ K+LEN + + +L + V DED+G NG +C + + K L N D + IYK++ SFDRE S V+I C D+G+ ++ I I+D NDNAPR +K+ F + EN+P + VG+V A D D N + +S+ + + NF I G EI S + FDRE+ D Y F VT D+G + Q + V+V I D +D P F+ ++Y FRI E YG ++ + ++KATD D+G N + Y + N + +A L ++ + F+G+ + GN DRE+ I L + A + G + + I + D+NDNAP N+S G + V DLD G NGT+T+ L ++ E F I + G + ++ ++K F+S RL I D G P ++I Y ++H
Sbjct: 27 VTFYTKEEIPIGNEIGNLKTRFSYPDGSQFNMLFPDSEIRRLFRLDSRTGALSTIARLDREVLCPNKPLECLRTFNVEVKRGGTGQEEVIVIRLIINDVNDQRPKFEAKHKKFRISIPESDNPPSYYSLPTAEDGDSDRYDHVKY------------DLKMIGDAGMYFKLFLEERGSKRV-PKLELTKALDRETKDNYELQLLVSDEQHPEDQDSADIQIEVLDANDNKPQWRLAKQSITISECDRLHRPLLKLNATDED----LNERITYSIGKAAG--KDVAKSFYISGDKLKQNQSLDYEKIRKKVLYIPLVAEDRGGSTVETYVELRVTDCNDHYPNITVEMIEDKILENDETEKVLARILVVDEDEGNNGTVDCVIGVPNKRKFQLTNRITDGQYKTIYKLKKLAHVSFDREATSGGEVRVDIICTDKGDSPRVGRKEVKIMILDENDNAPRIESKLYTFRIHENSPPNTLVGRVTARDDDIDENARLKFSLHSDGSRNFVIRNQGNNMAEIYSAVSFDREQIDHYRFTVTVADSGLKEQRTSTATVEVTIVDEDDSVPTFQFREYMFRIEEDYGRNLSKRYIGEVKATDADIGANQMIWYEV----------NRQYQASLADVGISGMYFYFNGSHLYGEGNFDREKQEIINLEIFARNRGPAKHKGSARVTITLNDVNDNAPSI---QGLQKVYNLSENSPAGTPVLQVSGTDLDAGENGTLTYIL---DETEANRFTIDGKHGIVTLSGSLKNNQPEDGFQSQTYRLGIGVRDNGNPPLHSIK--YTTFVH 789
BLAST of Protocadherin-11 X-linked vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 212.231 bits (539), Expect = 1.357e-55 Identity = 222/785 (28.28%), Postives = 363/785 (46.24%), Query Frame = 1
Query: 256 LPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSF-LDRETI--CENTKETCSMK-------LYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQT--GSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRD-DPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNI---RIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFD--DNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI----SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQP-EGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLN 2505
LP+S L K Y ++ +G++ +DRET+ C + C ++ L +Q I+ IE+ DINDN P F + +++QEN +G T+ +P A D+D+ + GV Y ++ F ++ + E++ P L ++ N+DRE S+ + A D G + S + V++TD NDNAP++ K +Y+ + E G +L++ AND D PN + +Q SD V ++ I + ++ + G ++R I + ++ A D + + + T V I + D ND+ P + I ++ + E+ + VQV D+D+G N + C + L+ DN Y ++T T D E+I Y VEI VD GNPA+SS + + D NDN+P F + E N G V V A+D DS N +VYSI+ + + GE++++ DRE + YEF VTA D G P + V +K+ D ND P F Y F + E+ + + D D G+N V+ + V+P ++ N + + G I + DRE+ SS ++A D G P S+ + I VLD NDNAPV PSN+ +F +S + V+ +D+D G N + +S+ N E F I P +GEI + KE + RL++K SD G+ ++ IA ++I +++N++
Sbjct: 84 LPDSGH--LYKLEVGAPYLRVDGKTGEIFTTEIPIDRETLKDCRIKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGP------------EASALFSLQMANDRGEKL-PQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDP------VPKMLQIERSTGIIS---VKGPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSVDNKKKYFLQTT--TPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENM---PPLSPVGMVTVLDMDKGENAQVQ---LSVEP-----------DVGNFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKPSNS-SFRRLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGNPHEL--FYISPSDGEIKLT---KELTRKHGGLHRLVVKVSDRGKPSRHAIALVHIYVNETISNVS 819
BLAST of Protocadherin-11 X-linked vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 211.075 bits (536), Expect = 1.571e-55 Identity = 222/785 (28.28%), Postives = 363/785 (46.24%), Query Frame = 1
Query: 256 LPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSF-LDRETI--CENTKETCSMK-------LYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQT--GSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRD-DPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNI---RIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFD--DNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI----SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQP-EGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLN 2505
LP+S L K Y ++ +G++ +DRET+ C + C ++ L +Q I+ IE+ DINDN P F + +++QEN +G T+ +P A D+D+ + GV Y ++ F ++ + E++ P L ++ N+DRE S+ + A D G + S + V++TD NDNAP++ K +Y+ + E G +L++ AND D PN + +Q SD V ++ I + ++ + G ++R I + ++ A D + + + T V I + D ND+ P + I ++ + E+ + VQV D+D+G N + C + L+ DN Y ++T T D E+I Y VEI VD GNPA+SS + + D NDN+P F + E N G V V A+D DS N +VYSI+ + + GE++++ DRE + YEF VTA D G P + V +K+ D ND P F Y F + E+ + + D D G+N V+ + V+P ++ N + + G I + DRE+ SS ++A D G P S+ + I VLD NDNAPV PSN+ +F +S + V+ +D+D G N + +S+ N E F I P +GEI + KE + RL++K SD G+ ++ IA ++I +++N++
Sbjct: 48 LPDSGH--LYKLEVGAPYLRVDGKTGEIFTTEIPIDRETLKDCRIKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGP------------EASALFSLQMANDRGEKL-PQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDP------VPKMLQIERSTGIIS---VKGPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSVDNKKKYFLQTT--TPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPL---SPVGMVTVLDMDKGENAQVQ---LSVEP-----------DVGNFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKPSNS-SFRRLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGNPHEL--FYISPSDGEIKLT---KELTRKHGGLHRLVVKVSDRGKPSRHAIALVHIYVNETISNVS 783
BLAST of Protocadherin-11 X-linked vs. Ensembl Cavefish
Match: ENSAMXT00000037569.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:10712701:10726912:1 gene:ENSAMXG00000037804.1 transcript:ENSAMXT00000037569.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 207.608 bits (527), Expect = 8.721e-55 Identity = 197/706 (27.90%), Postives = 321/706 (45.47%), Query Frame = 1
Query: 190 FSVDENCRIGHVVGNVYSKLN---QLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIP----------------IGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNN---IRIYITATD--GNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYK--IETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN--DNFAIS------IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLE----------QIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDN 2163
+SV E + G VVGNV LN Q + ++ + YF +N +G++ V +DRE +C + + CS+ L + + +F T V+++ +N P G YPLP A D D VKTY ++ + +F + ++ I P L + K +DRE+ + IL A D G +++G+ +++ V DVNDN P ++K+ YKV++ E G +++L A D D NG + Y L +++ + IF IN +T + G ++R + ++ A D + R + V I + D ND PPVIS+ + V E+ + + + D D G+NG + +G L+ A YK + DRE + Y+V I D+G P +SS +++I DVNDNAPRF + + +F+V EN+P G+ + V A D D + N IVYS++N D+ +S + G+I SK F+ E+ S++F V A D+G P L+ ++ V V I D ND PV Y S S+ E + +++A D D G N + Y + + K GN NL ++ S G I + ++ + L++ D G PSLS T ++ + V + D+
Sbjct: 35 YSVSEEVKAGTVVGNVAKDLNINVQDLEARMFRIIVSGSNKKYFEVNMKTGEMFVNERIDREELCSES-QACSLHL--------------EAIAQNPLRLFSVTVNVLDVNDNAPSFPYKSYDLNITELAFAGERYPLPKASDADVGVNSVKTYKLSANE----------------YFSLNVQSGGEQNISPQLVLQKALDREKQATVQLILTALDGGRPHRSGTLDLSINVIDVNDNTPAFSKEMYKVSVLENTLPGTPVIKLNATDLD--AGLNGEIVYSLISHGKEKW--ADIFAINSITGEIT---VKGPLDREDTAAFELHAQAQDKGSSPRASHCKVLIEVLDVNDSPPVISVTSLTSTVREDATTGTAVGLITIADNDIGKNGEVSAKVKGTGPFALQ--------ASYKNYYSLVVNGPLDREDMPQYSVTILATDKGTPPLSSSIVLAVDIADVNDNAPRFSDIVTVFYVKENSPSGNIIATVTAQDPDVNENAQIVYSLINRKNMDSSWMSMVDINPVSGDIYSKQSFNYEEVKSFQFKVQATDSGAPPLSSNVTVNVFIVDENDNRPVILPPY------SEAGSLNTENIPYSAEAGYFVGKVRAIDADSGYNALLSYHITEPK-----GN--------NLFRIGSSSGEIRTKRRMSDNDLKTHPLVITVCDHGEPSLSATVSVDVVVAESMDS 675 HSP 2 Score: 137.117 bits (344), Expect = 2.124e-32 Identity = 149/579 (25.73%), Postives = 253/579 (43.70%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYIN---GNKLHLTNNRI-SGLINRN---NIRIYITATDGNGRMNETSVDIAIE--DCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKI--ETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI----YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDY-FFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP---SNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI-QPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPT 2511
AP + +Y +NI E G+ L A+D D N + +Y+LS ++ F +N G + +++ + ++R +++ +TA DG ++D++I D ND+ P S VLEN + + D D G NG SL GK ++ D FAI I E DRE + + + + D+G+ +S K I ++DVND+ P V E+ G+ VG + D D NG + + + FA+ Y + DRE Y + A D G P L+ S+V+ V I D+ND P F F + E+ S + + A D D+ +N + Y LI+ K + + +++ + G I + + EE+ S Q VQA D G P LS+ T+ + ++D NDN PV L P + ++N N+ E G + V+ D D G N +++ + + + N F+I GEI M + ++ ++ P L+I D G+ + ++ + S+ ++ P+
Sbjct: 133 APSFPYKSYDLNITELAFAGERYPLPKASDAD--VGVNSVKTYKLS--------ANEYFSLNVQSGGEQNISPQLVLQKALDREKQATVQLILTALDGGRPHRSGTLDLSINVIDVNDNTPAFSKEMYKVSVLENTLPGTPVIKLNATDLDAGLNGEIVYSLISHGKE-----KWADIFAINSITGEITVKGPLDREDTAAFELHAQAQDKGSSPRASHCKVLIEVLDVNDSPPVISVTSLTSTVREDATTGTAVGLITIADNDIGKNGEVSAKVKGTGP-FALQASYKNYYSLVVNGPLDREDMPQYSVTILATDKGTPPLSSSIVLAVDIADVNDNAPRFSDIVTVFYVKEN---SPSGNIIATVTAQDPDVNENAQIVYSLINRK--------NMDSSWMSMVDINPVSGDIYSKQSFNYEEVKSFQFKVQATDSGAPPLSSNVTVNVFIVDENDNRPVILPPYSEAGSLNTENIPYSAEAGYFVGKVRAIDADSGYNALLSYHI--TEPKGNNLFRIGSSSGEIRTKRRMSD-NDLKTHP--LVITVCDHGEPSLSATVSVDVVVAESMDSVRPS 679 HSP 3 Score: 107.071 bits (266), Expect = 4.598e-23 Identity = 88/311 (28.30%), Postives = 148/311 (47.59%), Query Frame = 1
Query: 1447 AMSSMQKFSI--NIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKI--------KFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQ 2343
A + ++ FS+ N++DVNDNAP F K ++ E G +A D D N Y L++N+ F++++ + I DREK + + ++TA D G P + ++ + + + D+ND TP F K+ Y + E+ ++ + ++ ATD D G NG + Y LI S K + ++ + S G I+V G LDRE+ ++ +L QA D G ++ ++IEVLD+ND+ PV S V + G + + D D G NG ++ + + PF +Q
Sbjct: 113 AQNPLRLFSVTVNVLDVNDNAPSFPYKSYDLNITELAFAGERYPLPKASDADVGVNSVKTYK-LSANEYFSLNVQSGGEQNISPQLVLQKALDREKQATVQLILTALDGGRPHRSGTLDLSINVIDVNDNTPAFSKEMYKVSVLEN---TLPGTPVIKLNATDLDAGLNGEIVYSLI----------SHGKEKWADIFAINSITGEITVKGPLDREDTAAFELHAQAQDKGSSPRASHCKVLIEVLDVNDSPPVISVTSLTS---TVREDATTGTAVGLITIADNDIGKNGEVSAKV-----KGTGPFALQ 401
BLAST of Protocadherin-11 X-linked vs. Ensembl Cavefish
Match: ENSAMXT00000037829.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:10717406:10726912:1 gene:ENSAMXG00000037804.1 transcript:ENSAMXT00000037829.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 207.223 bits (526), Expect = 1.130e-54 Identity = 197/706 (27.90%), Postives = 321/706 (45.47%), Query Frame = 1
Query: 190 FSVDENCRIGHVVGNVYSKLN---QLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIP----------------IGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNN---IRIYITATD--GNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYK--IETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN--DNFAIS------IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLE----------QIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDN 2163
+SV E + G VVGNV LN Q + ++ + YF +N +G++ V +DRE +C + + CS+ L + + +F T V+++ +N P G YPLP A D D VKTY ++ + +F + ++ I P L + K +DRE+ + IL A D G +++G+ +++ V DVNDN P ++K+ YKV++ E G +++L A D D NG + Y L +++ + IF IN +T + G ++R + ++ A D + R + V I + D ND PPVIS+ + V E+ + + + D D G+NG + +G L+ A YK + DRE + Y+V I D+G P +SS +++I DVNDNAPRF + + +F+V EN+P G+ + V A D D + N IVYS++N D+ +S + G+I SK F+ E+ S++F V A D+G P L+ ++ V V I D ND PV Y S S+ E + +++A D D G N + Y + + K GN NL ++ S G I + ++ + L++ D G PSLS T ++ + V + D+
Sbjct: 45 YSVSEEVKAGTVVGNVAKDLNINVQDLEARMFRIIVSGSNKKYFEVNMKTGEMFVNERIDREELCSES-QACSLHL--------------EAIAQNPLRLFSVTVNVLDVNDNAPSFPYKSYDLNITELAFAGERYPLPKASDADVGVNSVKTYKLSANE----------------YFSLNVQSGGEQNISPQLVLQKALDREKQATVQLILTALDGGRPHRSGTLDLSINVIDVNDNTPAFSKEMYKVSVLENTLPGTPVIKLNATDLD--AGLNGEIVYSLISHGKEKW--ADIFAINSITGEIT---VKGPLDREDTAAFELHAQAQDKGSSPRASHCKVLIEVLDVNDSPPVISVTSLTSTVREDATTGTAVGLITIADNDIGKNGEVSAKVKGTGPFALQ--------ASYKNYYSLVVNGPLDREDMPQYSVTILATDKGTPPLSSSIVLAVDIADVNDNAPRFSDIVTVFYVKENSPSGNIIATVTAQDPDVNENAQIVYSLINRKNMDSSWMSMVDINPVSGDIYSKQSFNYEEVKSFQFKVQATDSGAPPLSSNVTVNVFIVDENDNRPVILPPY------SEAGSLNTENIPYSAEAGYFVGKVRAIDADSGYNALLSYHITEPK-----GN--------NLFRIGSSSGEIRTKRRMSDNDLKTHPLVITVCDHGEPSLSATVSVDVVVAESMDS 685 HSP 2 Score: 136.346 bits (342), Expect = 3.473e-32 Identity = 149/579 (25.73%), Postives = 253/579 (43.70%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYIN---GNKLHLTNNRI-SGLINRN---NIRIYITATDGNGRMNETSVDIAIE--DCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKI--ETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI----YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDY-FFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP---SNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI-QPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPT 2511
AP + +Y +NI E G+ L A+D D N + +Y+LS ++ F +N G + +++ + ++R +++ +TA DG ++D++I D ND+ P S VLEN + + D D G NG SL GK ++ D FAI I E DRE + + + + D+G+ +S K I ++DVND+ P V E+ G+ VG + D D NG + + + FA+ Y + DRE Y + A D G P L+ S+V+ V I D+ND P F F + E+ S + + A D D+ +N + Y LI+ K + + +++ + G I + + EE+ S Q VQA D G P LS+ T+ + ++D NDN PV L P + ++N N+ E G + V+ D D G N +++ + + + N F+I GEI M + ++ ++ P L+I D G+ + ++ + S+ ++ P+
Sbjct: 143 APSFPYKSYDLNITELAFAGERYPLPKASDAD--VGVNSVKTYKLS--------ANEYFSLNVQSGGEQNISPQLVLQKALDREKQATVQLILTALDGGRPHRSGTLDLSINVIDVNDNTPAFSKEMYKVSVLENTLPGTPVIKLNATDLDAGLNGEIVYSLISHGKE-----KWADIFAINSITGEITVKGPLDREDTAAFELHAQAQDKGSSPRASHCKVLIEVLDVNDSPPVISVTSLTSTVREDATTGTAVGLITIADNDIGKNGEVSAKVKGTGP-FALQASYKNYYSLVVNGPLDREDMPQYSVTILATDKGTPPLSSSIVLAVDIADVNDNAPRFSDIVTVFYVKEN---SPSGNIIATVTAQDPDVNENAQIVYSLINRK--------NMDSSWMSMVDINPVSGDIYSKQSFNYEEVKSFQFKVQATDSGAPPLSSNVTVNVFIVDENDNRPVILPPYSEAGSLNTENIPYSAEAGYFVGKVRAIDADSGYNALLSYHI--TEPKGNNLFRIGSSSGEIRTKRRMSD-NDLKTHP--LVITVCDHGEPSLSATVSVDVVVAESMDSVRPS 689 HSP 3 Score: 106.686 bits (265), Expect = 6.617e-23 Identity = 88/311 (28.30%), Postives = 148/311 (47.59%), Query Frame = 1
Query: 1447 AMSSMQKFSI--NIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKI--------KFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQ 2343
A + ++ FS+ N++DVNDNAP F K ++ E G +A D D N Y L++N+ F++++ + I DREK + + ++TA D G P + ++ + + + D+ND TP F K+ Y + E+ ++ + ++ ATD D G NG + Y LI S K + ++ + S G I+V G LDRE+ ++ +L QA D G ++ ++IEVLD+ND+ PV S V + G + + D D G NG ++ + + PF +Q
Sbjct: 123 AQNPLRLFSVTVNVLDVNDNAPSFPYKSYDLNITELAFAGERYPLPKASDADVGVNSVKTYK-LSANEYFSLNVQSGGEQNISPQLVLQKALDREKQATVQLILTALDGGRPHRSGTLDLSINVIDVNDNTPAFSKEMYKVSVLEN---TLPGTPVIKLNATDLDAGLNGEIVYSLI----------SHGKEKWADIFAINSITGEITVKGPLDREDTAAFELHAQAQDKGSSPRASHCKVLIEVLDVNDSPPVISVTSLTS---TVREDATTGTAVGLITIADNDIGKNGEVSAKV-----KGTGPFALQ 411
BLAST of Protocadherin-11 X-linked vs. Ensembl Cavefish
Match: ENSAMXT00000054364.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:10715673:10726912:1 gene:ENSAMXG00000037804.1 transcript:ENSAMXT00000054364.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 206.838 bits (525), Expect = 1.357e-54 Identity = 197/706 (27.90%), Postives = 321/706 (45.47%), Query Frame = 1
Query: 190 FSVDENCRIGHVVGNVYSKLN---QLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIP----------------IGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNN---IRIYITATD--GNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYK--IETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN--DNFAIS------IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLE----------QIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDN 2163
+SV E + G VVGNV LN Q + ++ + YF +N +G++ V +DRE +C + + CS+ L + + +F T V+++ +N P G YPLP A D D VKTY ++ + +F + ++ I P L + K +DRE+ + IL A D G +++G+ +++ V DVNDN P ++K+ YKV++ E G +++L A D D NG + Y L +++ + IF IN +T + G ++R + ++ A D + R + V I + D ND PPVIS+ + V E+ + + + D D G+NG + +G L+ A YK + DRE + Y+V I D+G P +SS +++I DVNDNAPRF + + +F+V EN+P G+ + V A D D + N IVYS++N D+ +S + G+I SK F+ E+ S++F V A D+G P L+ ++ V V I D ND PV Y S S+ E + +++A D D G N + Y + + K GN NL ++ S G I + ++ + L++ D G PSLS T ++ + V + D+
Sbjct: 40 YSVSEEVKAGTVVGNVAKDLNINVQDLEARMFRIIVSGSNKKYFEVNMKTGEMFVNERIDREELCSES-QACSLHL--------------EAIAQNPLRLFSVTVNVLDVNDNAPSFPYKSYDLNITELAFAGERYPLPKASDADVGVNSVKTYKLSANE----------------YFSLNVQSGGEQNISPQLVLQKALDREKQATVQLILTALDGGRPHRSGTLDLSINVIDVNDNTPAFSKEMYKVSVLENTLPGTPVIKLNATDLD--AGLNGEIVYSLISHGKEKW--ADIFAINSITGEIT---VKGPLDREDTAAFELHAQAQDKGSSPRASHCKVLIEVLDVNDSPPVISVTSLTSTVREDATTGTAVGLITIADNDIGKNGEVSAKVKGTGPFALQ--------ASYKNYYSLVVNGPLDREDMPQYSVTILATDKGTPPLSSSIVLAVDIADVNDNAPRFSDIVTVFYVKENSPSGNIIATVTAQDPDVNENAQIVYSLINRKNMDSSWMSMVDINPVSGDIYSKQSFNYEEVKSFQFKVQATDSGAPPLSSNVTVNVFIVDENDNRPVILPPY------SEAGSLNTENIPYSAEAGYFVGKVRAIDADSGYNALLSYHITEPK-----GN--------NLFRIGSSSGEIRTKRRMSDNDLKTHPLVITVCDHGEPSLSATVSVDVVVAESMDS 680 HSP 2 Score: 136.346 bits (342), Expect = 4.260e-32 Identity = 149/579 (25.73%), Postives = 253/579 (43.70%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYIN---GNKLHLTNNRI-SGLINRN---NIRIYITATDGNGRMNETSVDIAIE--DCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKI--ETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI----YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDY-FFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP---SNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI-QPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPT 2511
AP + +Y +NI E G+ L A+D D N + +Y+LS ++ F +N G + +++ + ++R +++ +TA DG ++D++I D ND+ P S VLEN + + D D G NG SL GK ++ D FAI I E DRE + + + + D+G+ +S K I ++DVND+ P V E+ G+ VG + D D NG + + + FA+ Y + DRE Y + A D G P L+ S+V+ V I D+ND P F F + E+ S + + A D D+ +N + Y LI+ K + + +++ + G I + + EE+ S Q VQA D G P LS+ T+ + ++D NDN PV L P + ++N N+ E G + V+ D D G N +++ + + + N F+I GEI M + ++ ++ P L+I D G+ + ++ + S+ ++ P+
Sbjct: 138 APSFPYKSYDLNITELAFAGERYPLPKASDAD--VGVNSVKTYKLS--------ANEYFSLNVQSGGEQNISPQLVLQKALDREKQATVQLILTALDGGRPHRSGTLDLSINVIDVNDNTPAFSKEMYKVSVLENTLPGTPVIKLNATDLDAGLNGEIVYSLISHGKE-----KWADIFAINSITGEITVKGPLDREDTAAFELHAQAQDKGSSPRASHCKVLIEVLDVNDSPPVISVTSLTSTVREDATTGTAVGLITIADNDIGKNGEVSAKVKGTGP-FALQASYKNYYSLVVNGPLDREDMPQYSVTILATDKGTPPLSSSIVLAVDIADVNDNAPRFSDIVTVFYVKEN---SPSGNIIATVTAQDPDVNENAQIVYSLINRK--------NMDSSWMSMVDINPVSGDIYSKQSFNYEEVKSFQFKVQATDSGAPPLSSNVTVNVFIVDENDNRPVILPPYSEAGSLNTENIPYSAEAGYFVGKVRAIDADSGYNALLSYHI--TEPKGNNLFRIGSSSGEIRTKRRMSD-NDLKTHP--LVITVCDHGEPSLSATVSVDVVVAESMDSVRPS 684 HSP 3 Score: 106.301 bits (264), Expect = 7.350e-23 Identity = 88/311 (28.30%), Postives = 148/311 (47.59%), Query Frame = 1
Query: 1447 AMSSMQKFSI--NIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKI--------KFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQ 2343
A + ++ FS+ N++DVNDNAP F K ++ E G +A D D N Y L++N+ F++++ + I DREK + + ++TA D G P + ++ + + + D+ND TP F K+ Y + E+ ++ + ++ ATD D G NG + Y LI S K + ++ + S G I+V G LDRE+ ++ +L QA D G ++ ++IEVLD+ND+ PV S V + G + + D D G NG ++ + + PF +Q
Sbjct: 118 AQNPLRLFSVTVNVLDVNDNAPSFPYKSYDLNITELAFAGERYPLPKASDADVGVNSVKTYK-LSANEYFSLNVQSGGEQNISPQLVLQKALDREKQATVQLILTALDGGRPHRSGTLDLSINVIDVNDNTPAFSKEMYKVSVLEN---TLPGTPVIKLNATDLDAGLNGEIVYSLI----------SHGKEKWADIFAINSITGEITVKGPLDREDTAAFELHAQAQDKGSSPRASHCKVLIEVLDVNDSPPVISVTSLTS---TVREDATTGTAVGLITIADNDIGKNGEVSAKV-----KGTGPFALQ 406
BLAST of Protocadherin-11 X-linked vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008517.1 (pep scaffold:Pmarinus_7.0:GL476786:43429:129410:1 gene:ENSPMAG00000007697.1 transcript:ENSPMAT00000008517.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 186.808 bits (473), Expect = 5.783e-48 Identity = 173/613 (28.22%), Postives = 287/613 (46.82%), Query Frame = 1
Query: 727 NIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNG--MFECSLNDSGKLNLKNIRFDDNFAIYK-IETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREK------TDSYEFVVTARDNGEPQ-LNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKN-ERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTS 2514
++DREE + + A D G+ VT+ V D D P + +D+Y + E + G ++ ++ D N V+Y + + D++ I + +G ++ N I+R Y + A G G E SV + + D N+H PV A+ + E++ +V+ D+D G+NG +E + G+ F I+ + Y DRE Y++ + +D G +SS ++ ++DVNDN P F + +FH E +GS VG V+A D D+ +NG + YS NF + S G I S FDRE S+ F V A D G P+ L D V+V +QD+ND P F K + S ES N +L ++ A+D D G NG ++Y + + GN K + + G I++ G+LDREE +S L+V A D G L+ + T+ ++VLD NDN P F + ++ V+ +G+ + T+ D D G +G + ++++ N F + G + +A + +F R RL + A D G+ P+++ AT+ + ++ N NP +
Sbjct: 615 SLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNAN---VTYLIV--SGDQRGSFSIEW-SGGRIFTAN-----AIDREEQAFYQLRVVANSG-GVAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGE----------KFGIFPDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVY---QASVSESASNLTQLLRVTASDVDEGVNGALRYAINE-------GNEGGKFTVD-----ASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRF---TESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAID-RSTGSVFLARRL-DFETQRLY--RLNVSAEDGGRPPRSS-ATILVVHVRDF-NDNPPA 1181 HSP 2 Score: 159.844 bits (403), Expect = 9.472e-40 Identity = 159/599 (26.54%), Postives = 268/599 (44.74%), Query Frame = 1
Query: 712 LEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQE-CQSEGD-----ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDS---GKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGN--PA-MSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILN-----------SNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASD 2433
L + +DREE S++ + A+D G ++V V D NDN+P +++ Y ++ E +G I ++A D D + G V+Y L+ +ED F ++ L R +R + ATDG G + + + D ND+ P + + +V E+ L + D+D+G N E S++ G+ + N D ++ + + DRE+ S Y + ++ D+ PA +SS + S+ + DVNDNAP F + E++P+G+ V V+A+D DS N ++ Y++ FA+ ++ GE++ + DRE SY V A D G P L + + V + D ND P F ++Y I E E E L ++ A D D G NG ++Y + P G + +L L G ++V LDRE +S +L V+A D G P+ S T ++ + + D+ND +P F ++ + + I V +D D G +G +T++ N F + P+G + H ++ LII A+D
Sbjct: 1572 LRASRRLDREERASYLLTVRASD-GTHATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDAD--SGPFGEVTYALAP-SEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGGLAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGN---DGQLSVAR-------ALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSAL-APEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAED--EPPGTEVL-RLSAWDPDEGANGELRYDIASGDPTG---DFRLDPVL---------GTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLSPYTVHARENTQGPPV--LILQVVARDDDLGSSGQVTYAAAGGNDGGA--FSVSPDGHV---HLLRSLDREAQPQHVLIITATD 2133 HSP 3 Score: 147.517 bits (371), Expect = 6.808e-36 Identity = 143/540 (26.48%), Postives = 224/540 (41.48%), Query Frame = 1
Query: 526 IGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNN-------IRIYITATDGNGRMNET-SVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSL-NDSGKLNLKNIRFDDNFAIYKI--ETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN--DNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITE-SYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFD 2097
IGT +A D DS +G TY +A + D + F + +L + + +DRE +V ATD G + + V V D NDNAP D+ + E G L I+ DD N + + +S + + + GN L+ R ++R +R+ A R++ V + + D ND+ P + + R E+ ++ TVQ D D GRN E +L D + FA+ + E DRE Y + + VD+G P ++S ++ + D NDNAPRF + + E+ P G+ V ++ A D D NG + Y I + + +F + + G + DRE+T SYE V ARD G P +D+ V+V + D+NDC+P F+ Y E + G + + Q+ A D DLG +G V Y + VS DG + + +LDRE L++ A D
Sbjct: 1641 IGTV----LAGDADSGPFGEVTYALAPSEDSDWAD------GAFGLHPVTG----------ALNVTRPLDRESRACYVLRARATDGGGLAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGV-NAELEFSISSGDPEGR------FAVGNDGQLSVARA---LDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFT-SPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLSPYTVHARENTQGPPVL---ILQVVARDDDLGSSGQVTY-------------AAAGGNDGGAFSVSPDGHVHLLRSLDREAQPQHVLIITATD 2133 HSP 4 Score: 135.961 bits (341), Expect = 2.566e-32 Identity = 152/564 (26.95%), Postives = 252/564 (44.68%), Query Frame = 1
Query: 730 IDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQS-EGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGR--MNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKI------SVYTVEIKCVDQGNP-AMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFP----FKIQPE-GEIIIA 2367
IDREE +F + + + G G +V+VLV DVN++AP + + +Y+V+I E + + A D+D + KNG V Y++ + K IF + +R + R + ++A D + +V++ + D ND+ P+ + ++ E Q+ ++ VQ D D G NG S + F+ + +I + FDRE + + ++ + D G P + + + DVNDN P+F + V E+ + + +V A D+D NG + Y+I N+ ++ G+I DRE+T SY VV+A D+G L S V V++ D ND P F + ++ + E L + A+D+D G +G V+Y ++ GN+ + G++ + LD E +L V A D G P S+ T +++ V D NDN P FL P + F ++ IG + TV +D D +NG + +S+ FP F I PE GEI A
Sbjct: 719 IDREE-QAFYQLRVVANSGGVAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKD--SGKNGEVKYEIGEGNGGEKF--GIFPDGQLYVRYELDRET----REEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEK------PQVNFELDSETGRIASL--RVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAINEGNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLS--VDALESTRVGELLITLTASDEDTGPSGDVRYAIV-------AGNTHATFAIDRST-----GSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFL-PGD--VFASIMENIPIGTRVITVTARDPDADVNGELHYSIA-----RQFPPGAHFTIDPESGEICTA 1243 HSP 5 Score: 133.65 bits (335), Expect = 1.255e-31 Identity = 135/562 (24.02%), Postives = 240/562 (42.70%), Query Frame = 1
Query: 844 PEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLEN-----QKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIE-----TYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN--DNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGE---PQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRL-IDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYI 2475
P + ++ ++E EG+ I L A D D +N LV+Y + +E F ++ L +R R + + + A+DG + + +A+ D ND+ P S V E+ + + ++ TV D D G G +L S + D F ++ + T P DRE + Y + + D G +++ + +N++D NDNAP N V E+ P G+++ ++ A D D N + +SI + + FA+ G++ DRE+ Y VV D +L+ ++ V + + D+ND P F R + +S + ++A D D G+N V+Y L D + G + N + G + + LDRE S L V A D G P L++T T+ + V D NDNAP FP ++ + G + + D D+G NG + + + + + + F++ P G + +A + R+ L ++A D G +++ A++ +
Sbjct: 1514 PVFAVPEMELEVEENTGEGEVIFTLSATDAD--QGQNALVTYSVLSGSE------GAFVVDAASGVLRASRRLDREERASYLLTVRASDGT-HATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWA----DGAFGLHPVTGALNVTRP---LDRESRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSP---RSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVT----GEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAP--RFPRREYE-AAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGD--FRLDPVLGTLAVA---RPLDRERTASYELAVRARDGGGPARSDTASVRV 2042 HSP 6 Score: 127.872 bits (320), Expect = 6.222e-30 Identity = 114/458 (24.89%), Postives = 203/458 (44.32%), Query Frame = 1
Query: 1129 TSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGA-ISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAH-----TMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYI 2475
TS+ + + D ND PP+ + +EN + + +V D D G NG + + + + F + K+ T S DRE++ Y + ++ D+G+P + S K ++ + D+NDN P F ++EN P G+ V V A D D NG + Y + + F + ++ G + +++ DRE+ Y+ VTA D G + +V + + D D P F + DY F + E+ + + A+ DL N V Y ++ + R + + G I +DREE + QL V A G ++ ++ + V D+N++APVF S V+++ + + +V+ D D G NG + + + N E F I P+G++ + + T +E+S L + A D G P ++ T+ +
Sbjct: 430 TSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREM-FRLDSLTGKVTTL--KSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVNAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVA---PGTLVGSVSASTLDL--NANVTYLIV-------------SGDQRGSFSIEWSGGRIFTANAIDREEQAFYQLRVVANSGG---VAGEASVSVLVHDVNNHAPVFDRASYE---VSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEK--FGIFPDGQLYVRYELDRETREEYS--------LTVSAMDTGVEPLSSSVTVNV 850 HSP 7 Score: 119.398 bits (298), Expect = 2.695e-27 Identity = 107/404 (26.49%), Postives = 175/404 (43.32%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVEN-NPIGST----VGQVRAMDLDSSNNGHIVYSILNSNDN------FAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDG-YPS--LSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSL 2301
V+I++ED ND+PPV ++ +V EN + ++ T+ D D+G+N + S+ + D + + DRE+ + Y + ++ D + ++ + S+ + D NDN+PRF F V E+ P G T +G V A D DS G + Y++ S D+ F + + G + DRE Y A D G L + + V + D ND P + D E ++ L +I ATD D G N +++ + P G V DG +SV LDRE S L+V+ D +P LS+ + + + D+NDNAP F P + + + +G + TV+ D D G N + ++L
Sbjct: 1502 VEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSE---GAFVVDAASGVLRAS----RRLDREERASYLLTVRASDGTH---ATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGG--GLAATARLYVNVLDANDNAPSVQNDSL--AAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEG-------------RFAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSAL----APEDSPVGAVVATVQAVDPDSGRNSYVEYAL 1874 HSP 8 Score: 107.842 bits (268), Expect = 8.713e-24 Identity = 100/360 (27.78%), Postives = 165/360 (45.83%), Query Frame = 1
Query: 1444 PAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI--SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNER--LEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM-KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLN 2505
P MSS + I++ DVNDN P F V EN G + + A D D N + YS+L+ ++ + + G +++ + DRE+ SY V A D D+ + V ++D ND +P F + Y F + E K R + + A D D G G V Y L + +S L V+ GA++V LDRE + L +A D G L+ T + + VLD NDNAP N+ V + G ++ + D D+G+N + S I+S E F + +G++ +A + +E +F + L+++ SD ++P +++ +R LT++N
Sbjct: 1494 PPMSSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFVVDAASGVLRASRRLDREERASYLLTVRASDGT--HATDAR-LSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSE------DSDWADGAFGLHPVT--GALNVTRPLDRESRACYVLRARATDGG--GLAATARLYVNVLDANDNAPSV---QNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFS-ISSGDPEGR-FAVGNDGQLSVARALDRERQSFYN----LVVRVSDRARHPPARLSSA-VRVSLILTDVN 1830 HSP 9 Score: 93.2041 bits (230), Expect = 2.436e-19 Identity = 151/571 (26.44%), Postives = 238/571 (41.68%), Query Frame = 1
Query: 331 GDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFV------SFVFILIATDFGNQ---TGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSE-GDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGNGRMNETSVDIAIE--DCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISV-------------YTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISI-YGEIQSKIKFDREKTDS-YEFVVTARDNGEPQLNDSMVVK---VKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKY 1935
G L V+ LDRET E + +M ++ + ++ + + + D+NDN P+F ++ V + E +G+ A D D+ G TY + Q NF+ S+ I SL + DRE + SF F ++ATD G TV V V DVNDN P++ K Y+ ++ E S +L + A+D D+ NG + Y +++ E K F ++ + +T + G ++R Y ++ATD S +A++ D ND+PP + + LE+ + +L T+ DED G +G D +AI T+ + DR SV Y + + D G P SS +++ D NDN P F+ ++EN PIG+ V V A D D+ NG + YSI +F I GEI + + DRE T +E V A D P +K V + D ND P F + + + ++A+D D +N V+Y
Sbjct: 812 GQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQ------------VNFEL------DSETGRIA-SLRVF---DREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDE--GVNGALRYAINEGNEGGK-----FTVDASTGQIT---LLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLITLTASDEDTGPSG-------------------DVRYAIVAGNTHATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAILVDGL--RAAAGSVVGTLQASDPDEAENAAVRY 1329 HSP 10 Score: 90.8929 bits (224), Expect = 1.391e-18 Identity = 84/300 (28.00%), Postives = 124/300 (41.33%), Query Frame = 1
Query: 1474 INIIDVNDNAPRFVNKIKM-FHVVENNPIGSTVGQVRAMDLDSSNNG--HIVYSILNSNDNFAI--------SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAP----VFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
+ + DVNDNAP F M E+ +G V A+D D NG H Y I++ N+ + + + + DRE SY V A D G P+ + V V +QD ND P FEK +Y S+ + + A +DL G P+ +P + K G +S LD E L ++A D G P LS T +I++LD+NDN P V+L P+ V+ S + TV D NG ++ S++ N+R +F
Sbjct: 11 VVVGDVNDNAPSFPEPGVMEVAFKEDAAVGRQVLLDTAVDRDVGPNGVNHHAYKIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEK-------PAYRASVAED--SPVGAALRDLLHRGR--------GPLAVPFDPKT-------------GMVSTRQPLDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDAD-SPTANGELSVSIVGGNERGHF 279 HSP 11 Score: 81.2629 bits (199), Expect = 1.059e-15 Identity = 99/419 (23.63%), Postives = 161/419 (38.42%), Query Frame = 1
Query: 1129 TSVDIAIEDCNDHPP------VISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFE-----CSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYG--ESIKNERLEQ-IKATDKD-LGQNGTVKYRLID--------VKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYP-SLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSN 2313
T V + + D ND+ P V+ +A F + +Q ++ T V D D G NG+ S N+ G+L F ++ T P DRE Y + ++ D G+P + ++ + D NDN P F V E++P+G+ + DL G + G + ++ D E Y + A D G P L+ +++ D+ND P Y S ES + + TD D NG + ++ + G+PG LK V LDRE I L + A D+G P + S T ++++ V D+ND+AP F + + G + V D D G+N + +S+++ N
Sbjct: 7 TEVRVVVGDVNDNAPSFPEPGVMEVA--FKEDAAVGRQVLLDTAV---DRDVGPNGVNHHAYKIVSGNEEGRLVPPRPVTKRAF-LHLATTGP---LDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAAL-----RDLLHRGRGPLAVPFDPKT--------GMVSTRQPLDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLK----------------VASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGA---PAGSYVKDVTAMDADSGLNAKLRYSIVSGN 384
BLAST of Protocadherin-11 X-linked vs. Ensembl Sea Lamprey
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 175.252 bits (443), Expect = 5.809e-45 Identity = 201/736 (27.31%), Postives = 312/736 (42.39%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVS---QIFYINGNKLHLTNNRISGLINRNN---IRIYITATDGNGRMNET--------------SVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSL-NDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI-LNSNDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYF-FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSIG-------KKSHSSDNNNFGFRLKNDNK 2580
F +++ EN P G +P+ A D DS GV+ Y + + + F++ ++ E P L + K++DREE + L A D G+ +GS + + VTD NDN+P + + V I E G +++L A+DRD N V Y+L T ++F ++ N +T ++GL+NR RI I ATD S I I D +++ N + E + + + V D D G NG C + N LK + + + + + ET D E + Y V+IK D G ++S +I ++D NDNAP F V ENN IG + V A D D N +VY + ++ F + G I + DREK +Y F + A+D G P L + V V + D+ND P F F F + E+ K+ + + D D G+NG V+ S L + R L + + G I DRE+ L VQA D G P S+T ++I V+D+NDN+P+ L P +N + V G + V D D IN + + ++ N N F I P G I + + E + RL+++ SD+G +++ L +++ T N T I + +D FG R + DNK
Sbjct: 153 FAAPVLTVSVPENAPAGKRFPIQPANDPDSEANGVRRYEL-----------LPSDPATVSAFELSVTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRD--AGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVT---VNGLLNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRD------IVAPVNGVIYISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEVPFQLKKLTYPNQYLLETRET-----LDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDKNAEMVYFLGPDAPTMFHMDPETGIISLTEQLDREKKANYSFTILAKDQGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNENVP---KHSTVGMVTVADSDEGENGRVRL-------------SILGTDNRQLFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGGEPVRSSTVKVVIHVMDINDNSPIVLMPPSNTTYKFVVPRTLPGTIVTEVSAVDNDAEINAELRYHIVGGNPH-NL-FHIDPVIGNITLMEPLTETHHGLH---RLVVRVSDIGIAVQHHAVALVHVFVNE-TLENATYIEWLIAGSLQTPLDTDVAGFGRREQEDNK 839 HSP 2 Score: 95.9005 bits (237), Expect = 2.783e-20 Identity = 113/430 (26.28%), Postives = 181/430 (42.09%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGM--FECSLNDSGKLNLKNIRFDDNFAIYKIE-TYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY-----------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDY------FFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEII 2361
V I +ED ND+ P + V EN D D NG+ +E +D ++ + + K+ S DRE+ +Y + ++ VD G+P S IN+ D NDN+P F + EN+P+G+ V Q+ A D D+ +N +VY + S G + +RE++ Y ++ A D G + + V V + D+ND +P E +D I+E+ S N + I +D D+G NG V + N ++ +L+ L + + LD E + + ++A D G SLS T ++ I++LD NDNAPVF P+ ++ +V IGK + TV D D N + + L F + PE II
Sbjct: 139 VRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVIYISEA---SHVNLPVALITVSDPDIGANGAVTCYIY---------NPEVPFQLKKLTYPN-QYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNV---IGKHLITVSATDRDMDKNAEMVYFL---GPDAPTMFHMDPETGII 549
BLAST of Protocadherin-11 X-linked vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010725.1 (pep scaffold:Pmarinus_7.0:GL479425:26296:30457:-1 gene:ENSPMAG00000009713.1 transcript:ENSPMAT00000010725.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 169.088 bits (427), Expect = 5.364e-43 Identity = 207/815 (25.40%), Postives = 339/815 (41.60%), Query Frame = 1
Query: 190 FSVDENCRIGHVVGNVYSKLNQL-----PNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXX-------------XXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGID-QENQVKTIGNNFQFFQIKNPKSKQEEI--YPSLEIIKNIDREEFVSFVFILIATDFGNQ--TGSCXXXXXXXXXXXXAPEWTKDNYK-VNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQI-FYINGNKLHLTNNRISGLINRNNI---RIYITATDGNGRMNETSVDIAIE--DCNDHPPVISIANRFG--------KVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNK------IKMFHVV--ENNPIGSTVGQVRAMDLDSSNNGHIVYSI--LNSNDN----FAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-------DYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLI-DVKP--IGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTI-CTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLG 2439
+ VDE +G+V+G++ N L P + S + + S +N SG+L V LDRE +C + C ++ A + + P F+ ++I E+ +G PLP A D D+ ++ Y I+ G Q + ++ + LE+ + +DRE S+ +L D GN +GS +T++V D NDNAP + + V I E G +++L A D D NG ++Y T+ + +Q +++G L R + ++R + R+ + A DG SV + +E D ND+ PV + G K++EN + + V D D G +G + L L + N + ++T D E+ Y V + D+G P +S + I+++D+NDN P F+N + ++ V EN P G+ V + A D DS NG I +++ L ++ F++++ G++ DREK YE V A D G PQ +V+V + D ND P F Y F + E E+ + + +D D G N V L+ + P IG G++ G + LDRE+ +L V+A D G P+LS + + I V D NDNAPV P+ N + +V G + +V D+D G NG + +I N + F G + +A T+ RL+++ D G
Sbjct: 31 YEVDEEVLVGYVIGDLRQS-NLLCVCFFPPAPHVSPLPLHTP-SLCIVNELSGELSVALRLDREALCMEEPDACRSTGFMHTVQVAAMAKGQGSSNLRLLDVQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPD--AGPNGAIAYSF--HTKLTSLATQAALHVDGTT-GLVTVRNAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLEFPTGAELAS----PNKVQFLLKTT--RLLDYEEAQQYNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEE---ETSVGTYVGTVSTSDLDEGDNARVALNLVREAGPDWIGGAGDTP-------------GGVVRTLVVLDREDRVQYELSVRAVDSGRPALSASCRVSITVSDTNDNAPVITSPNTNDTWKHVRTFSPAGMLVGVSVTANDIDAGDNGRPLYEIIGGNPKGIFLLNAD-SGALSLARTVSSLDEGLH---RLVVRVRDRG 812
BLAST of Protocadherin-11 X-linked vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004042.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 147.902 bits (372), Expect = 5.574e-36 Identity = 131/473 (27.70%), Postives = 202/473 (42.71%), Query Frame = 1
Query: 1012 FYINGNKLHLTNNRISGLI---------NRNNIRIYITATDGN---GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL---NSNDNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTM 2376
+ + G H + N +G I R + + +TA DG G + ++ +A+ D NDH P A + + V +D D G NG SL+ S D + I R+ + T+ ++ D G P S++ ++ D + PRF + F E+ P G+T+ V A S G + Y + N D FA+ GE+ D E YE VV ARD+G P + + ++V + DIND P F F+ E+ + + A DKD G NG V Y +ID GN + N+ +V+ + G I LDRE ++S +L V+A D G P+ T ++I V D NDN+P F + +V + +G + V T D D+G N IT SL++ + PF I P GEI ++ +
Sbjct: 63 YRLRGGDGHFSVNPSTGQIITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSASAGFS---VDPRRGV--IHAARALQGPRDDL---TLTVRVSDGGAPPRSAVTTVTVRFRDAGE-FPRFAPGPRSFSFREDQPPGTTITVVAARS--SRRAGPVSYHLASGGNLGDVFAVDPQSGEVSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVP---ENTPPRTIVVLTAVDKDSGINGQVDYSIID-------GN------IGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRF----TQIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLD----PSLPFSIHPSTGEITVSRRL 500 HSP 2 Score: 123.635 bits (309), Expect = 1.402e-28 Identity = 122/452 (26.99%), Postives = 191/452 (42.26%), Query Frame = 1
Query: 1108 GNGRMNET-SVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQG-NPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS-NDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE---KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQP-EGEIIIAHTMKEFSNFRSLPDRLIIKASDLG 2439
G R+ T +V + +ED ND+ P A V E+ + V D D G N + S +L + F N + +I T S DRE Y +E+ +D G P +SS + + DVND+ PRF+N + + + P G+ V V A D D+ NG + +S+ S + F++ + + + D V D G P + V V+ +D + P F + + FR + G +I + + G V Y L L ++ V G +SV+ LD E +L+V+A D G+P S + ++VLD+NDNAP F ++ F E +TI + D D GING + +S+I+ N F++ P GEI T+ N S L +KA+D G
Sbjct: 2 GEPRLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDAPIGSDVALVNATDADAGLNAII------SYRLRGGDGHFSVNPSTGQIIT--TASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSASAGFSVDPRRGVIHAARALQGPRDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGE-FPRFAPGPRSFSFREDQPPGTTITVVAARSSR-------RAGPVSYHLAS------------GGNLGDVFAVDPQSGEVSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEF----SSSRFWAKVPENTPPRTIVVLTAVDKDSGINGQVDYSIIDGNIGNV--FRVNPNSGEIRSVSTLDR-ENVASY--ELTVKATDRG 416 HSP 3 Score: 123.635 bits (309), Expect = 1.462e-28 Identity = 157/639 (24.57%), Postives = 264/639 (41.31%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXX--XXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGNGRMNETSVD--IAIEDCNDHPPVISIANRFGKVL-----ENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI-YGEIQS--KIKF-DREKTDS------YEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIK-NERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
F + + +E+ P GTT + V + S + G +Y++A + GN F + +P+S + ++ + +D E + ++ A D G S + + V ++ DNAPE++ + + E I+ L A D+D + NG V Y + D + +F +N N + R ++R N+ Y + ATD +V I++ D ND+ P RF ++ E+ + V D D+G N SL D ++ F + + +I +RE S Y V+++ D PA + +I + DVNDNAPRF E + + V +V A D D NG + + + + +NF + GEI S +++ D S Y FVVTA D G P L+ V + I N P F ++ R + +++ R+ + A D D NG + Y ++ GN+ + V G + + +L + S + V+A D G P LS+ T II V + N AP F P ++ G ++ V D D G+NG I +S+ + + F
Sbjct: 232 FAPGPRSFSFREDQPPGTT--ITVVAARSSRRAGPVSYHLA------------SGGNLGDVFAV-DPQSGEVSVH------RALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVVLTAVDKD--SGINGQVDYSIIDGN-----IGNVFRVNPNSGEI---RSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSP------RFTQIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLD------PSLPFSIHPSTGEITV--SRRLNREDRSGYAVKVRASD---PAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLRE---RYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVG-------GNASRR------FDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPE---NHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLF 803 HSP 4 Score: 113.62 bits (283), Expect = 1.633e-25 Identity = 136/563 (24.16%), Postives = 232/563 (41.21%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQL--NDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGIN-GTITHSLINSNKRENFPFKIQPEGEIIIAHTM-----KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYI 2475
AP + ++++ E G L + A D D NG + Y ++ + D + I +G+ L + G ++ ++Y + A DG + + V I++ D ND+PP+++ ++ + + EN + + D D N + SL+D G+ +L + + + + D E Y + ++ + + S + + I VN+ PRFV + F V E+ P+G+ VG V A D D+ +G + Y + + + S+ GEI + DRE+ S V A++ G + D ++V V I D ND PVF Y R++E+ + + + A D D LI GN+ R + G I V LDRE + L V A D G P + TT +++ + D+NDN P L S V+ G T+ ++ D D N G T L+ S+ F + G + A + EF L + +D G P + TL++
Sbjct: 752 APRFAHPPLELSLPENHPAGSSLARVTATDTD--AGVNGAIVYSIA--SGDGSGLFDISRASGDVL------LVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSLDD-GEADL--FVLNQKTGVLTTQGF----LDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEA---ASVGTHVVGVSAHDFDSPPGWRTFSFLIQS------GNAG-----RAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLLTSS-----AKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEF--------HLPVAIADAGSPPLTSTVTLHL 1269 HSP 5 Score: 112.464 bits (280), Expect = 3.527e-25 Identity = 138/538 (25.65%), Postives = 229/538 (42.57%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDIL--ELIANDRDDPNTKNGLVSYQLSDRTEDRKI---VSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETS-----VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVK---------DEDKGRNGMFECSLNDSGKLNLKNIRFD-DNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--FAIS-IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSL--STTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM 2376
AP + + Y + E SEG+ L + A+D DD NG V + + +TE+ ++ +I + + SG N N +TA D GR +S ++I + + N A RF L + + TV+ D D+ NG S+ + RFD D + S + S+++V ++ D+G P +SS I++ + N APRF + + EN+P GS++ +V A D D+ NG IVYSI + + + F IS G++ + D E Y V A D G + V + + D+ND P+ DY+ I E+ + + + A D D N Y L D G + L + G ++ G LD E + +L V+AF+ YP +T + +++ +N+ P F+ NFV VS +G + +V D D GI+GT+ + L ++ + F + GEII++ +
Sbjct: 536 APRFGQTAYYIEFPE-PSEGEALVARVSASDADD--GANGQVFFFMRSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSG-ANLNKYSFVVTAMD-RGRPPLSSDATVTINIVVPNAN--------APRF---LRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNA----SRRFDVDAGGFLHLRA----SLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPEN---APSGTTVLVMDAVDADSPSNAVTMYSLDD-------GEADL------FVLNQKTGVLTTQGFLDYETKQTYELTVRAFN--YPDTFHYSTAQVHVQITGVNEYFPRFV--QREYNFV-VSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVN-EHTGEIIVSSQL 1027 HSP 6 Score: 82.0333 bits (201), Expect = 6.755e-16 Identity = 80/277 (28.88%), Postives = 120/277 (43.32%), Query Frame = 1
Query: 1378 TSFDREKISVYTVEIKCVDQGNPAMSSMQKFSIN-------IIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL----NSNDNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITE--SYGESIKNERLEQIKATDKDLGQN-GTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDN 2163
+ DRE+ + T+ + + G S++ F ++ I D ND P F + + V E +G+ V V A D DS G +S L N+ F+I+ + G I DRE Y V A D GEP + VV V ++D+ND P F ++TE G ++ N ++A D DL N G ++L+ P R +S G + +DRE+ L V D G P L++T T+ + VLD NDN
Sbjct: 1025 SQLDREREASATLRVIAKNAG-----SIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPP-GWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGP-FLLTSSAKVTENQPAGMTVLN-----LEAGDPDLPPNKGPYTFQLLGSDPA-----------WRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDN 1277 HSP 7 Score: 80.4925 bits (197), Expect = 2.298e-15 Identity = 71/249 (28.51%), Postives = 108/249 (43.37%), Query Frame = 1
Query: 1744 GEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDG-YPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSV-EWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPD-RLIIKASDLGQNPKNNIATLYIRY 2481
GEP+L + V V ++D ND P F R I ++ + + ATD D G N + YRL G G+ + +I + +LDRE S L V A D G P LS++ T+++ V D+ND+ P FL N +V + G + V +D D G NG + SL S F + P +I H + R D L ++ SD G P++ + T+ +R+
Sbjct: 2 GEPRLTGTGTVTVLVEDENDNLPRFGAAEL-RAAVPEDAPIGSD-VALVNATDADAGLNAIISYRL-----RGGDGHFSVNPSTGQIITTA---------SLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFL----NAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSASAG---FSVDPRRGVI--HAARALQGPRD--DLTLTVRVSDGGAPPRSAVTTVTVRF 223
BLAST of Protocadherin-11 X-linked vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004043.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004043.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 147.517 bits (371), Expect = 7.423e-36 Identity = 131/473 (27.70%), Postives = 202/473 (42.71%), Query Frame = 1
Query: 1012 FYINGNKLHLTNNRISGLI---------NRNNIRIYITATDGN---GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL---NSNDNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTM 2376
+ + G H + N +G I R + + +TA DG G + ++ +A+ D NDH P A + + V +D D G NG SL+ S D + I R+ + T+ ++ D G P S++ ++ D + PRF + F E+ P G+T+ V A S G + Y + N D FA+ GE+ D E YE VV ARD+G P + + ++V + DIND P F F+ E+ + + A DKD G NG V Y +ID GN + N+ +V+ + G I LDRE ++S +L V+A D G P+ T ++I V D NDN+P F + +V + +G + V T D D+G N IT SL++ + PF I P GEI ++ +
Sbjct: 63 YRLRGGDGHFSVNPSTGQIITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSASAGFS---VDPRRGV--IHAARALQGPRDDL---TLTVRVSDGGAPPRSAVTTVTVRFRDAGE-FPRFAPGPRSFSFREDQPPGTTITVVAARS--SRRAGPVSYHLASGGNLGDVFAVDPQSGEVSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVP---ENTPPRTIVVLTAVDKDSGINGQVDYSIID-------GN------IGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRF----TQIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLD----PSLPFSIHPSTGEITVSRRL 500 HSP 2 Score: 123.25 bits (308), Expect = 1.700e-28 Identity = 122/452 (26.99%), Postives = 191/452 (42.26%), Query Frame = 1
Query: 1108 GNGRMNET-SVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQG-NPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS-NDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE---KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQP-EGEIIIAHTMKEFSNFRSLPDRLIIKASDLG 2439
G R+ T +V + +ED ND+ P A V E+ + V D D G N + S +L + F N + +I T S DRE Y +E+ +D G P +SS + + DVND+ PRF+N + + + P G+ V V A D D+ NG + +S+ S + F++ + + + D V D G P + V V+ +D + P F + + FR + G +I + + G V Y L L ++ V G +SV+ LD E +L+V+A D G+P S + ++VLD+NDNAP F ++ F E +TI + D D GING + +S+I+ N F++ P GEI T+ N S L +KA+D G
Sbjct: 2 GEPRLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDAPIGSDVALVNATDADAGLNAII------SYRLRGGDGHFSVNPSTGQIIT--TASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSASAGFSVDPRRGVIHAARALQGPRDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGE-FPRFAPGPRSFSFREDQPPGTTITVVAARSSR-------RAGPVSYHLAS------------GGNLGDVFAVDPQSGEVSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEF----SSSRFWAKVPENTPPRTIVVLTAVDKDSGINGQVDYSIIDGNIGNV--FRVNPNSGEIRSVSTLDR-ENVASY--ELTVKATDRG 416 HSP 3 Score: 123.25 bits (308), Expect = 1.729e-28 Identity = 157/639 (24.57%), Postives = 264/639 (41.31%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXX--XXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGNGRMNETSVD--IAIEDCNDHPPVISIANRFGKVL-----ENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI-YGEIQS--KIKF-DREKTDS------YEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIK-NERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
F + + +E+ P GTT + V + S + G +Y++A + GN F + +P+S + ++ + +D E + ++ A D G S + + V ++ DNAPE++ + + E I+ L A D+D + NG V Y + D + +F +N N + R ++R N+ Y + ATD +V I++ D ND+ P RF ++ E+ + V D D+G N SL D ++ F + + +I +RE S Y V+++ D PA + +I + DVNDNAPRF E + + V +V A D D NG + + + + +NF + GEI S +++ D S Y FVVTA D G P L+ V + I N P F ++ R + +++ R+ + A D D NG + Y ++ GN+ + V G + + +L + S + V+A D G P LS+ T II V + N AP F P ++ G ++ V D D G+NG I +S+ + + F
Sbjct: 232 FAPGPRSFSFREDQPPGTT--ITVVAARSSRRAGPVSYHLA------------SGGNLGDVFAV-DPQSGEVSVH------RALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVVLTAVDKD--SGINGQVDYSIIDGN-----IGNVFRVNPNSGEI---RSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSP------RFTQIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLD------PSLPFSIHPSTGEITV--SRRLNREDRSGYAVKVRASD---PAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLRE---RYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVG-------GNASRR------FDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPE---NHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLF 803 HSP 4 Score: 113.235 bits (282), Expect = 2.306e-25 Identity = 136/563 (24.16%), Postives = 232/563 (41.21%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQL--NDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGIN-GTITHSLINSNKRENFPFKIQPEGEIIIAHTM-----KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYI 2475
AP + ++++ E G L + A D D NG + Y ++ + D + I +G+ L + G ++ ++Y + A DG + + V I++ D ND+PP+++ ++ + + EN + + D D N + SL+D G+ +L + + + + D E Y + ++ + + S + + I VN+ PRFV + F V E+ P+G+ VG V A D D+ +G + Y + + + S+ GEI + DRE+ S V A++ G + D ++V V I D ND PVF Y R++E+ + + + A D D LI GN+ R + G I V LDRE + L V A D G P + TT +++ + D+NDN P L S V+ G T+ ++ D D N G T L+ S+ F + G + A + EF L + +D G P + TL++
Sbjct: 752 APRFAHPPLELSLPENHPAGSSLARVTATDTD--AGVNGAIVYSIA--SGDGSGLFDISRASGDVL------LVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSLDD-GEADL--FVLNQKTGVLTTQGF----LDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEA---ASVGTHVVGVSAHDFDSPPGWRTFSFLIQS------GNAG-----RAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLLTSS-----AKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEF--------HLPVAIADAGSPPLTSTVTLHL 1269 HSP 5 Score: 112.464 bits (280), Expect = 4.205e-25 Identity = 138/538 (25.65%), Postives = 229/538 (42.57%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDIL--ELIANDRDDPNTKNGLVSYQLSDRTEDRKI---VSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETS-----VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVK---------DEDKGRNGMFECSLNDSGKLNLKNIRFD-DNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--FAIS-IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSL--STTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM 2376
AP + + Y + E SEG+ L + A+D DD NG V + + +TE+ ++ +I + + SG N N +TA D GR +S ++I + + N A RF L + + TV+ D D+ NG S+ + RFD D + S + S+++V ++ D+G P +SS I++ + N APRF + + EN+P GS++ +V A D D+ NG IVYSI + + + F IS G++ + D E Y V A D G + V + + D+ND P+ DY+ I E+ + + + A D D N Y L D G + L + G ++ G LD E + +L V+AF+ YP +T + +++ +N+ P F+ NFV VS +G + +V D D GI+GT+ + L ++ + F + GEII++ +
Sbjct: 536 APRFGQTAYYIEFPE-PSEGEALVARVSASDADD--GANGQVFFFMRSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSG-ANLNKYSFVVTAMD-RGRPPLSSDATVTINIVVPNAN--------APRF---LRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNA----SRRFDVDAGGFLHLRA----SLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPEN---APSGTTVLVMDAVDADSPSNAVTMYSLDD-------GEADL------FVLNQKTGVLTTQGFLDYETKQTYELTVRAFN--YPDTFHYSTAQVHVQITGVNEYFPRFV--QREYNFV-VSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVN-EHTGEIIVSSQL 1027 HSP 6 Score: 82.0333 bits (201), Expect = 7.530e-16 Identity = 80/275 (29.09%), Postives = 118/275 (42.91%), Query Frame = 1
Query: 1378 TSFDREKISVYTVEIKCVDQGNPAMSSMQKFSIN-------IIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL----NSNDNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQN-GTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDN 2163
+ DRE+ + T+ + + G S++ F ++ I D ND P F + + V E +G+ V V A D DS G +S L N+ F+I+ + G I DRE Y V A D GEP + VV V ++D+ND P F ++TE+ + LE A D DL N G ++L+ P R +S G + +DRE+ L V D G P L++T T+ + VLD NDN
Sbjct: 1025 SQLDREREASATLRVIAKNAG-----SIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPP-GWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGP-FLLTSSAKVTENQPAGMTVLNLE---AGDPDLPPNKGPYTFQLLGSDPA-----------WRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDN 1277 HSP 7 Score: 80.1073 bits (196), Expect = 2.787e-15 Identity = 71/249 (28.51%), Postives = 108/249 (43.37%), Query Frame = 1
Query: 1744 GEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDG-YPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSV-EWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPD-RLIIKASDLGQNPKNNIATLYIRY 2481
GEP+L + V V ++D ND P F R I ++ + + ATD D G N + YRL G G+ + +I + +LDRE S L V A D G P LS++ T+++ V D+ND+ P FL N +V + G + V +D D G NG + SL S F + P +I H + R D L ++ SD G P++ + T+ +R+
Sbjct: 2 GEPRLTGTGTVTVLVEDENDNLPRFGAAEL-RAAVPEDAPIGSD-VALVNATDADAGLNAIISYRL-----RGGDGHFSVNPSTGQIITTA---------SLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFL----NAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSASAG---FSVDPRRGVI--HAARALQGPRD--DLTLTVRVSDGGAPPRSAVTTVTVRF 223
BLAST of Protocadherin-11 X-linked vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 182.185 bits (461), Expect = 2.469e-46 Identity = 174/566 (30.74%), Postives = 255/566 (45.05%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGNGRMNETS--VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPD-----TSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVF---LFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIH 2487
+P ++ NY I E G ++ + A D D + G + Y+L V F I+ N + R+S ++R Y + A DG +S V IA++D ND+ P+ F +V E+ + V D D NG +L+D N ++ I T T D EK + Y V + D G P+ SS+ + + DVNDN P+F + V EN G V V A D DS NG I YSIL+ N+N A ++ GEI +++ DRE SY + A D + + V + I D ND P F F I+E +S R+ Q+ ATD+D+G NG V Y +I G GNS + + R+ G +SV LDRE I S L+V+A D G P S T +I + VLD+NDNAP F LF + + + T+ VK +D D+G NG IT SL + +N F I G +++ T ++ + +L + A D G K+ A + I I+
Sbjct: 475 SPVFSPSNYSKQIPESTVIGSTVVTVTATDLD--SGPRGRLEYRLISGN-----VKGAFNIDANSGSI---RVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVF-RVSESSSPGHQIGQVAATDADDSSNGDVRYALSD-------------NTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNISE---DSPTGTRVGQLTATDRDIGPNGAVTYAIIS----GNQGNS-FQLDPRS-------GILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSG------EIREDASVHSTVLQVKVEDKDEGSNGAITLSL-SGEGSDN--FTIDSTG-FVLSKTPLDYETTAAY--QLTVTARDGGSPSKSATAQVKITIIN 989 HSP 2 Score: 172.555 bits (436), Expect = 2.222e-43 Identity = 205/734 (27.93%), Postives = 330/734 (44.96%), Query Frame = 1
Query: 277 SLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQS-EGDILELIANDRDDPNTKNGLVSYQLSDRTEDR-KIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRF--VNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI-LNSNDNFAIS-IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPD-RLIIKASDLG 2439
S++ NE + F+++R +G++ + LDRETI + + L + A + I I D NDN P F T NI E+ P GT A D+D G TY I NQ GN+FQ +P+S L + +DRE S+ ++ A+D G+ Q+ + ++ V V DVNDNAP + K + I+E S +L++ D+D+ + NG ++ LS D I S F ++ L ++ +TA DG + V I I + ND+ P + + E+ + + D D G F+ ++G + + D + + + DRE + YT+ ++ + G+ S +I ++DVNDNAP F + K H EN PIG TV +V A D D N + Y + + F ++ G + +K DRE SY VTA D+G+P + + + I D+ND +P F + Y +TE+ + + ++ A+D D G NG V Y +I GN N ++ S G I+V G +DRE ++S L + A D G P +T + I V D NDN+P+F ++N + IG + V D D+G N + +S++ + + F I ++ T+K+ N ++P L I+ASD G
Sbjct: 723 SILSGNE-NMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTF-TGPSRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISG------NQ----GNSFQL----DPRSGI------LSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGS--NGAITLSLSGEGSDNFTIDSTGFVLSKTPLDYETTAA--------YQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSD-GTPLTFDIVEGNAG----SSFKIDQSSGLISVAKR----LDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLH--ENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTEN---TANGSNILRVLASDPDAGANGRVTYSIIS-------GNHG------NAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIF---ASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIV---RGDTSAFAINAMNGVL---TVKKEINRETVPTYTLTIRASDRG 1388 HSP 3 Score: 159.458 bits (402), Expect = 2.092e-39 Identity = 147/502 (29.28%), Postives = 232/502 (46.22%), Query Frame = 1
Query: 844 PEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNK-LHLTNNRISGLI------NRNNIRIY---ITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILN-SNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGT-VKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVE-WEIGKTICTVKTKDLDQGINGTITHSL 2301
P++ K Y + E + G + + A D D + NG +SY + ++GN+ + +R +G I +R I Y I A DG+ M T+V+I+I D ND+ P + +RF + E+ + + D D G NG ++ + N + + D I + + + DRE I YT+ +K D G+P S ++++DVNDNAPRF + + E+ + STV QV+ D D +NG I S+ +DNF I G + SK D E T +Y+ VTARD G P + + VK+ I ++ND P F ++T + N + ++ ATD D GT + + +++ GN+ ++ G ISV LDRE ++ L+V+A + G S I VLD+NDNAPVF N ++ E IG+T+ V D D+G N +T+ L
Sbjct: 683 PQFAKSLYTCTVGENLAAGVAVCYVTATDAD--SGANGKISYSI---------------LSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSRF-NISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGN--SFQLDPRSGILSVRS----TLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGSDNFTIDSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPA--QVTSIPEDVAINTHVVKLNATDSD----GTPLTFDIVE-------GNAGSSFKIDQ-----SSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVF----NPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYEL 1138 HSP 4 Score: 154.451 bits (389), Expect = 8.255e-38 Identity = 138/514 (26.85%), Postives = 227/514 (44.16%), Query Frame = 1
Query: 1081 IRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNG--MFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI---SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYG--ESIK-NERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKT-ICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYI------------RYIHSLTNLNPTSIG-KKSHSSDNNNFG 2556
+R T + G N + I + D ND+ PV + + + EN + V D D+G N +E S+ D+ K F+ N A + T DRE + Y++ + +D G P+ S++ ++ I D+NDN+P+F V EN GS + +V A D D+ NG + YSI++ N A S G I DRE SY ++A+D+G P + V + + D ND +P+F + SYG E + R+ + ATD+D G N V Y ++ + + + +G ++V ++RE + + L ++A D G P +++ + + V D+NDN PVF N+ +++ E T + TV D D G N + +S+I+ N + FKI +I+ T +F L + A+D K N+ I Y S+ +PTS K +SD ++FG
Sbjct: 1069 VRATETGSQGESVYNNAT--IRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSK-------FEVNPATGLVTT--KRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASN-----ETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIV-------------RGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVF----NSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKR--FKINSTSGVIMTTTPLDFEEKSQY--GLEVTATDSKYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSFG 1545 HSP 5 Score: 145.206 bits (365), Expect = 5.528e-35 Identity = 157/554 (28.34%), Postives = 244/554 (44.04%), Query Frame = 1
Query: 724 KNIDREEFVSFVFILIATDFGNQT--GSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLI---------NRNNIRIYITATDGNGRMNETSVD-IAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI---SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGA---ISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
+ DRE + ++A D N+ G V + V D NDNAPE+ ++Y NI+E + + A DRD + N ++Y L + NK + N +G I +++ + I+A DG + T V I ++D ND+ P +++ V E+ I+ + D D G N SL SG + + D+ + + + +FDRE + Y V ++ D G+P+ S I I+DVNDN P F + V E+ IG+ + V A D D+ NN + YS + N N A ++ G + D E+ SY ++ D G P L D+ + + + DIND PVF Y R+ E+ Q+ ATD+D NG + + +I G+ + DG+ IS+ + D E + L VQA D G P T + I + D+ND++PVF PSN + S IG T+ TV DLD G G + + LI+ N + F
Sbjct: 26 RKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQVAIVTATDRD--SGTNAAITYSL--------------FSGENKFMM--NSKTGEIRTVTPLDHETKDSYTMRISAFDGK---HTTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLV-SGDTSYFTV---DSQGVIRTKG----AFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT------QVSATDRDSSTNGALVFGIIKGNDDGV---------------FTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVF-SPSNYSKQIPEST--VIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAF 526 HSP 6 Score: 140.198 bits (352), Expect = 1.824e-33 Identity = 197/752 (26.20%), Postives = 339/752 (45.08%), Query Frame = 1
Query: 304 SYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEII---KNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGN-----KLHLTNNRIS--GLINRNNIRIY---ITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDN-FAIYKIETYPDT--SFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSND--NFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYI 2484
S F ++++SG + V LDRET T + + ++ I + D+NDN PVF ++ EN+PIG T A D+D + TY ++ +G+ +F E+ P+ ++ + +DRE+ S+ + A D G +Q+ +T+ + D+NDN+P++++ Y + + E + G +IL ++A+D D NG V+Y + I+GN ++ T RI+ G+++R + Y I+A D ++ V I + D ND+ P+ + + E + V D D+G N S+ +R D + FAI + +RE + YT+ I+ D+G+P M+S ++ ++ + DVNDN P F ++ + V EN+ ++V V A D D N + YSI++ ND F I S G I + D E+ Y VTA D+ + V +++ ++ND TP F +++Y + E+ S + + ++ A+D+D G++ Y + +G + K + R+ G IS LDRE +S + V+ D G P LS T + I++LD NDN+P F S + + + S + D D+G N IT++L N F I +I + N +S D L I+A D G P+ + T+ + I
Sbjct: 1040 SSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELS-------------VGDTSKF-----------EVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPD--AGANGRVTYSI---------------ISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSI----------VRGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQNYTASVREN---SPTSTSVVKVSASDRD--SFGSLSYSI-----VGGKDSDKFSIDQRS-------GIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAAT---DADEGTNARITYNL-----SRNDAFMIGASSGVITLAQPLDREN-KSTYD-LAIQARDHGTPPQASSITIRVTVI 1710 HSP 7 Score: 134.035 bits (336), Expect = 1.465e-31 Identity = 141/527 (26.76%), Postives = 233/527 (44.21%), Query Frame = 1
Query: 712 LEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLE----QIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLD 2268
L + K I+RE ++ + A+D G+ T +TV+V DVNDN P + +Y +++E ++ + +A D D N ++ Y + ++++ F IN + ++ + +TATD +T+V I + + ND P + N V EN + V D R+ S + G + D I DRE +S+Y ++++ D GNP +S++ +I I+D NDN+P+F + ++EN+ S ++ A D D N I Y+ L+ ND F I G I DRE +Y+ + ARD+G P S+ ++V + DIND P+ G +N+ E +I A+D D G N + + L L E +++ + + G IS LDRE+ + L + D G PSLS+ +II+V+D +DN P F N V +S G +I V +D+D
Sbjct: 1364 LTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVG-ANAVLRYSIISGNDEKR-----FKINSTSGVIMTTTPLDFEEKSQYGLEVTATDSK-YTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASD----RDSFGSLSYSIVGGKDSDKFSIDQRSGIISTADV----LDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYN-LSRNDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSL------RGSVRENQPKETHVMRILASDADTGLNAELTFSL-------------LSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRFQPTEYN---VTISESLPRGASIVQVTARDID 1852
BLAST of Protocadherin-11 X-linked vs. Ensembl Nematostella
Match: EDO48237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF4]) HSP 1 Score: 180.644 bits (457), Expect = 7.662e-46 Identity = 152/480 (31.67%), Postives = 231/480 (48.12%), Query Frame = 1
Query: 1162 DHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDT--SFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAISIYGEIQSKI----KFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIK-NERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVS-FDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVE-WEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI-QPEGEIIIAHTMKEFSNFRSLPD-RLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSIGKKSHS---SDNNNFG 2556
++PP S V E+ + ++ TV D D G NGM S++ S +N+ F+I +I T DRE + + +K D G P++ +IN++DVNDN P F I + E+ IG V VRA D DS +NG + Y ILNS+ DN A SI GE+ + K DREK +Y V A+D G P + ++ VK+ + D+NDCTP F K + + + E + N+ + ++ATD D G NG V + ++ GN N ++ +G + V LD E I LLV A D G P L TT+ I ++D+NDNAP F+ + +F + E + +G+ V+ D D G NG IT S + + + PF I + G I ++KE + +P IKA D G K A + I + N NP ++ + ++N+ +G
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPS-----QNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSI-GEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVY---SATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVS-------GNDM------NFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFV----SSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFM----QNDLPFSINENTGGI----SIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLD--INDNPPKFSQEEYHTSIAENSRWG 458 HSP 2 Score: 169.088 bits (427), Expect = 2.731e-42 Identity = 145/526 (27.57%), Postives = 247/526 (46.96%), Query Frame = 1
Query: 844 PEWTKDNYKVNIQECQSEGDILELIANDRDDPNT-KNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGL----INRNNIRIYITATDGNGRMNETSVDIAIE--DCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFE-CSLNDSGKLNLKNIRFDDNFAIYKIETYPDT--SFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--FAIS-IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYF-FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLI-DVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM 2376
P++++ ++ E G ++ ++ DP++ NG++ Y +S + + F I+ +T R GL ++R+ R+ A DG E +D+ I D ND+ P+ + E++ + V+ D D G NG + C LN G + F+I ++ DREK+ YT++++ DQGNP S+ I ++DVND P+F K+ + E+ P+ V VRA D D +NG + + I++ ND F+I+ I GE++ K K D E + +VTA+D G+P L + V + + D+ND P F +F I E+Y + +++A DKD G NG + + + + P I N+ G IS+ LDRE++ ++A D G P T I I +LD+NDN P F S +++ G ++ VK D D G + +S+++S+ + F+I P+G I ++ T+
Sbjct: 18 PQFSRLQEDASVSEDAEVGTVVATVS--ASDPDSGSNGMIRYSMSP--SQNLMSATYFSIDQITGVITTKR--GLDREFLDRHFFRV--KAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGD--------NSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYA---VGQEFYRVQAYDKDHGTNGEITFSFMQNDLPFSINENT---------------GGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKF---SQEEYHTSIAENSRWGTSVLQVKAIDPDSGPT-NVVYSIVSSSGHDRC-FRINPQGLITLSCTL 504 HSP 3 Score: 153.295 bits (386), Expect = 2.237e-37 Identity = 212/800 (26.50%), Postives = 344/800 (43.00%), Query Frame = 1
Query: 178 LNVEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDS-------YFSLNRTSGDLIVKSFLDRETI--------CENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDR--DDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTN-NRISGLINRNN---------IRIYITATDGNGRM--NETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN---FAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNER-----LEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD---GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPD-RLIIKASDLGQNP 2448
L + SV E+ +G VV V + P+S + +++ + S YFS+++ +G + K LDRE + E+ E S++ Y+D + D+NDN P+F+ +I E+ IG A D DS G Y I G +N +IG E+ ++ ++K +DRE+ ++ + A D GN ++ + TV + + DVND P+++K Y I+E + + +L+ R D NG V +++ ++GN ++ + NRI+G + + +TA D N+T+VDIA+ D ND+ P ++ + EN VQ D+D G NG S N ++N I+ DREK+ +T IK D+G P + +I ++D+NDN P+F + + EN+ G++V QV+A+D DS ++VYSI++S+ + F I+ G I + Y F V+A D L+ + +V V + D N P F++ SY +K + + + ATD+D G N + Y + + P + S D G I G+LDRE++ + + V A D G P L + + I + D+NDN PVFL PS V + G + V D D G N I +S SN F I II T+K ++P+ L + A+D G P
Sbjct: 23 LQEDASVSEDAEVGTVVATVSA---SDPDSGSNGMIRYSMSPSQNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEP-SLEGYMDLTINV-------LDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDG---DNSAFSIG----------------EVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIRE---DVPVNQLVTTVRATDCDQGSNGEVFFEI---------------VSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQ----NDLPFSINENTGGISIK----EELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPT-NVVYSIVSSSGHDRCFRINPQGLITLSCTLNYNTKHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKR-------RSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVP-----------------EFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYE---AKVREDIRPGGRVIEVSASDADIGKNAQIIYSFA-SNGDGQGTFTIDSTQGII--RTLKPLDR-ETIPEYELTVVATDQGTPP 731 HSP 4 Score: 129.028 bits (323), Expect = 6.341e-30 Identity = 175/638 (27.43%), Postives = 263/638 (41.22%), Query Frame = 1
Query: 307 YFSLNRTSGDLIVKSFLDRETI-----CENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYI-TATDGNGRMNETS-VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN---FAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVF 2175
+FS+NR +G++ VK LD E I ++ LY I + N FQT I EN +G + A DKD G T F F Q P S E + I + +DRE+ F F + A D G + G+ +T+ + D+NDN P+++++ Y +I E G +L++ A D D T +V +S DR F IN L +S +N N +Y+ + + +G ++ T+ V + + D N H P + +V E+ + TV D D G N S+ + D+ + K S DREK+ Y E+ D G P + + I+I DVNDN P F+ V E+ G V +V A D D N I+YS ++ D F I S G I++ DRE YE V A D G P S+ VKV ++D+ D P+FEK Y + E ++ + +KA +DL + Y ++ GNS ++ GAI LD E S +L V+A T TT+++ + D+NDN PV
Sbjct: 281 FFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTM-----IPENYAVGQEFYRVQAYDKDHGTNGEIT---------------------FSFMQNDLPFSINENT-GGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTN--VVYSIVSSSGHDR-----CFRINPQGLI----TLSCTLNYNTKHVYVFSVSASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATL----VPEFSVDETTGVIKTA----GSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPE---DTPPRSPVITVKAKSQDLSPETGMMYSIVR-------GNSPQVFDIN-----PNTGAIQTLMKLDYETQSEYRLTVRA---TLSPFFTETTVMVYLKDINDNTPVL 854 HSP 5 Score: 116.316 bits (290), Expect = 4.628e-26 Identity = 177/707 (25.04%), Postives = 291/707 (41.16%), Query Frame = 1
Query: 271 RSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTI-GNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG-----NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATDGNGRMNETSVDIAIE--DCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYK---IETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNE-----RLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
+ ++ ++ +S FS+ SG + V LDRE + T + + + + + I + D+ND P F I+E++P+ A D D QG + E + + GN+ FF I I + + + +D E F ++ A D G NQT TV + + DVNDNAP++ +++ I E + G + + A D+D + NG +++ F IN N ++ I ++R + + I A D E + I I D ND+PP S + EN + + V+ D D G + ++ SG D F I I +++ + + V++V + +SS +N+ D N +AP F + V E+ +G++V V A D D+ +N I YSI F++ G I++ DREK D+Y F VTA D+G PQL V + I D+ND PVF K SY ++ + R+ ++ A+D D+G+N + Y G + S G I LDRE I +L V A D G P + + + + D+ D+ P+F P + V V + + TVK K D + +S++ N + F
Sbjct: 164 KYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCD--------------QGSNGEVFFEIVSGNDMNFFSIN-------RINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQT---TVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKD--HGTNGEITFSFMQN-------DLPFSINENTGGIS---IKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGH--------DRCFRINPQGLITLSCTLNYNTKHVYVFSVS-----ASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLK-------PSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFAS----NGDGQGTFTID-------STQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKP---LYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSPQVF 800
BLAST of Protocadherin-11 X-linked vs. Ensembl Nematostella
Match: EDO40470 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S751]) HSP 1 Score: 160.614 bits (405), Expect = 1.115e-39 Identity = 141/495 (28.48%), Postives = 211/495 (42.63%), Query Frame = 1
Query: 1075 NNIRIY---ITATDGNG--RMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLN---DSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGY-PSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSL----PDRLIIK--ASDLGQNPKNNIATLYIRYIHSLTNLNPT 2511
N+ R Y + A DG R + +++ + D ND+ PV + VLE + V D D G NG + + D+ K L+N + + + DRE I Y +++ +D G P SS + + DVNDN P F F V EN P+ + +G V A D D +NGH+ Y F + G+I + DRE SY F + A D G D V V ++D+NDC+P F K+ + +T + + + L I D G N + Y ++ + KA N + G +++ LDRE L V A D G SL T T I I VLD+NDN PVF+ N F V + IG + V D DQG NG + + ++N N +G I T S R+L +R +++ A+D+G+ + L Y+ + PT
Sbjct: 873 NSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKFGLRN----------GGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNK-YSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIV----------AGPKAFSLNQVT----GVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFI---NETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNT----------DGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPT 1329 HSP 2 Score: 148.673 bits (374), Expect = 6.260e-36 Identity = 150/540 (27.78%), Postives = 250/540 (46.30%), Query Frame = 1
Query: 724 KNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGR--MNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNF--------AISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRL---IDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWE-IGKTICTVKTKDLDQGINGTITH 2295
+ +D E S+ F + ATD G ++ + TV V +TD+NDN P + +Y V E G I +L A DRD P K + + + D ++F ++G+ L +T ++ ++N + + A DG G+ +N+ V+I + D ND PP+ S A + E+ + ++ V DKG N S++ K N NI ++ Y + D EKI + ++ D+G P + +I +ID+NDN+P+F + + + E+ PIG T V D DS G + +S+L++ A+S+ +K+ SY V A+D G P + + ++++K+ D+ND +PVF Y + E+ + + + ++ ATD D G+NG + Y +D G LRN G I + LDRE+I L V A D G P S++ + + V D+NDN P F ++ E E + + V D D+G NG +T+
Sbjct: 557 RTLDHEVQSSYTFQVAATDGGGRSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSP--KFAITRFIIEQGNAD-----EVFSVDGSGL-ITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSIS---KGNTDNIVLINSTGTL----YLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGTLFNLDSNTGALSL-----TKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLET---TPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKFG----------LRN------GGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHF----QQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTY 1053 HSP 3 Score: 132.109 bits (331), Expect = 6.900e-31 Identity = 190/699 (27.18%), Postives = 305/699 (43.63%), Query Frame = 1
Query: 304 SYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLI-----------NRNNIRIYITATDGNGRMNE-TSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDT--SFDREKISVYTVEIKCVDQGNPAM-SSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI--LNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNG---EPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
S F L R G + +KS LDRE I E + ++ + + + + + ++D+NDN P FQ ++EN P+ T A D D G TY + QV QF KQ + +++ DRE S+VF ++ATD G+ + VTV+V DVND +P+++K+ Y V + E G +L LIA D DD N ++Y + + G K + N+++G++ +R+ + + + GN + T ++I + D ND+ PV F V E ++ V D D+G NG + + N D F I + T + D E + Y + + D G +S Q +I + D NDN P F + + EN PI + V ++A D DS N I Y+I + +F I S G IQ+ DRE+ Y V A D + +L ++ +K+ IQD+ND P F + E + N ++ I A D D GQ G V+YR++ P K +L+ G + + G+LD E++ L + A D G P L++ + V+D+NDN P F + ++ VS G ++ V D D G N +T+S+ + + + F
Sbjct: 958 SKFGL-RNGGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRF--------DTQVA------QFI-----VDKQTGKITTSQVL---DREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATD-DDQQGPNSDITYMI---------------VAGPKA-FSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKV--------RYKIVNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSRNLTYVME---DEPFNFQVTSITALDPDTGQGGNVEYRIVS------PDTGKFSLDLKT-------GVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEF---TRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKF 1589 HSP 4 Score: 123.635 bits (309), Expect = 2.783e-28 Identity = 152/559 (27.19%), Postives = 249/559 (44.54%), Query Frame = 1
Query: 727 NIDREEFVSFVFILIATDFGNQTGS--CXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQ-LSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFA-ISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISV-----YGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKT-ICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIII 2364
++DRE+ V ++ D G+ S C+V V +TD NDN P + + +Y ++ E G +++L+A D D +N L+ Y L+ T F+++ K +TN+R +++ + ATDG GR +V +++ D ND+ PV ++ + EN + + ++ D D + + + + ++ + K+ DRE Y + +K VD G + +I ++DVND P F F + E++ S +G V A+ D N +VYSI N DN I+ G + + + D EK S V A+D G P L V + + DIND +P F R+ E ++ + D D G G V + L + PG L NL S GA+S+ YGN R S L VQA D G P S+T + ++V+D+ND +PVF N ++ +E + I V D+D G NG I+++ +K + F ++ G+I I
Sbjct: 455 DLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPD--IGENSLILYSILTPNTP--------FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSVDGSGLITLAKL-------LDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPE---DTPIGHTFYTVSVFDADSGVLGRVSFSL-----LSNPGT------LFNLD--SNTGALSLTKLIDYGNSAR----SYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVF----GNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAF--DSKVDTSKFGLRNGGKIFI 970 HSP 5 Score: 122.865 bits (307), Expect = 4.360e-28 Identity = 149/525 (28.38%), Postives = 227/525 (43.24%), Query Frame = 1
Query: 985 EDRKIVSQIFYI---NGNKLHLTNNRISGLI------NRNNIRIY---ITATDG----NGRM-NETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSL--NDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS--NDNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAH-----TMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIR 2478
+D + S+I+Y + H N +GLI +R I Y + ATD R+ N ++ I I+D ND+ P ++ V+E++ +T++ D D G+ G E + D+GK +L D + K+ S D E + YT+ I D G+P ++S Q F++ ++DVNDN P F + + V EN P G++V +V A D DS +N + YSI + D F+I + G I + DREK D+Y V A P S V++ + D ND P F +T E+ + + D D G N V Y ++ G + EL K LDRE +S QL VQA D P + I I + D NDN PVF ++ +S G +I + D D G NG I ++L N + I I+ + ++K+ NF + A D GQ+PK I + I+
Sbjct: 1357 DDSGLNSRIWYTIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKF-VSRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGKFSL-----DLKTGVLKLIG----SLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPV---VTLKVPENSPARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTK------------LDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVF---QQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSNDTYGV---YSIDSRTGIVYSAARFETSIKQEYNFFCI-------AKDQGQDPKMAIVPVRIK 1843 HSP 6 Score: 115.161 bits (287), Expect = 9.587e-26 Identity = 102/343 (29.74%), Postives = 156/343 (45.48%), Query Frame = 1
Query: 1387 DREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI----SIYGEIQSKIKFDREKTDSYEFVVTARDNGEP-QLNDSMVVKVKIQDINDCTPVFEKDYF----FRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWE---IGKTICTVKTKDLDQGINGTITHSLINSNKRENF--PFKIQPEGEIIIAHT 2373
DRE++ Y + I D GNPA + SI + D NDN P F N + EN +G+++ QV A D D N I YSI +D AI G I + ++ D E SY VV A D G QL+ S +V++++ D+ND PV Y +++TE+ + ++ ++ +D D G+NG V L G G +K ++ N + I+V +LDRE L D G P +T + I V D+ND AP F + + V WE + + V D D G N + +++ N+ + ++ F I P +I T
Sbjct: 131 DRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTEN---ATIGTQVARVSVSDADSGKNGEVNVTL-----EGGDGYFSMKFDVLN-----DESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKF-----DRHTYETRV-WENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTAT 454 HSP 7 Score: 112.464 bits (280), Expect = 6.117e-25 Identity = 125/493 (25.35%), Postives = 206/493 (41.78%), Query Frame = 1
Query: 844 PEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYING-NKLHLTNNRISGLINRNNIRIYITATDG-NGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDED--KGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIET-----YPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKM-FHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI-----YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQ 2271
P + + Y I E G IL L A+D+D + NG + Y LS+ T ++ I+ + + R I + I G + +M V I IED N+H P + + N ++T V D D K NG L+DS KN + +++ +E+ F + + I D G+P + I I ++ D+ PRF+N+ + EN+ +GS + VRA +S++ + YSI++ N A + + S D E T ++ + A G LN M++ + + D ND +P F + ++ E G + K + ++ ATD D G NG V Y + G+ S G I+ LDRE +S L+++ D G P ST + + V DLNDN P+F + ++ VN+ + G + +V D D+
Sbjct: 1748 PVFQQSLYSSTISELTPPGTSILNLTASDKD--SGSNGNIVYTLSNDTY------GVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDS-----KN-----STSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRAR---ASSDAQVTYSIISGNKGRAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTG-AFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGV------------FTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLF----DPLSEVNIREDTRTGAVVTSVVATDTDK 2202 HSP 8 Score: 111.309 bits (277), Expect = 1.717e-24 Identity = 193/719 (26.84%), Postives = 297/719 (41.31%), Query Frame = 1
Query: 277 SLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELI-ANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIR--IYITATD-GNGRMNETS-VDIAIEDCNDHPP-VISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGST--VGQVRAMDLDSSNNGHIVYSILNSNDN--FAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITES-----------YGESIKNERLE--------------QIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLD-REEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGIN-GTITHSLINSN 2313
S+M N D F++ R++G+L + LDRET + + T I I I D NDN PVFQ + I E P GT+ A DKDS G N V T+ N+ + + + S+ +Y + +I +E + F IA D G + V + + D N++AP++TK Y+V+I S ++ ++ A D D + NG V+Y+L +D K + +F + N + + +G N R +YI A D G+ + V I I + D PP ++ + EN K +TTV+ + + S N + D F I + D E + + + QG +++ IN+ID NDN+P F + + E+ V +V A D+DS NG + YSI N+ F I S GEI + DRE T S++ V+ D+G P + + VKV + D+ND P+F+ I E ++ K RL ++ ATD+D G N +KY PI K + G IS +D R S IQ+ VQA D G P + I + P F PS F V +G ++ TV+ D G+ G I++++ NSN
Sbjct: 1683 SIMSGN-TDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNG---------------NIVYTLSND--TYGVYSIDSRTGIVYSAARFETSIKQE----YNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRL----DDSKNSTSLFVVESNTGSVRTS--AGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSDAQVTYSIISGNKGRAF------YVDPFTGV-ISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSF----PITNSDQIDYKIDADT-------GVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIIIT----REPKFELPS---YFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSN 2348 HSP 9 Score: 105.145 bits (261), Expect = 1.241e-22 Identity = 109/403 (27.05%), Postives = 164/403 (40.69%), Query Frame = 1
Query: 1117 RMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNG--MFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY-GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIK-NERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSN 2313
R E S I + D ND P +V EN ++ V D+D G N ++ + + L D + + T DRE+I + + D+G+P +S +N+ D NDN P F + EN+P GS V Q+ A D D N I+YSIL N F + G + + D E SY F V A D G N V V + D+ND PVF+ + + Y E+ + + + Q+KA D+D + ++ + GN+ + V G I++ LDRE + L V+A D G + I VLD+ND P+F N S + I V D+G N + +S+ N
Sbjct: 369 RTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTAT----DLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCN--ATVHVSLTDLNDNQPVFDPSSY---SVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQ-------GNAD------EVFSVDGSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSV---IGHVHAISRDKGTNAEVVYSISKGN 746 HSP 10 Score: 98.5969 bits (244), Expect = 1.032e-20 Identity = 75/277 (27.08%), Postives = 129/277 (46.57%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSL---NDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRF-VNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--FAISIY-GEIQSKIKFDREKTDSYEFVVT--ARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKY 1935
V I + D ND PV + + E I+ V D+D G NG ++ +D G + D + + + + D E I + V ++ D+G+P M + +I ++D+NDN P F V V+EN P+ S + ++ A D DS N + ++++ F I + G + + I FD E T Y++ +T A D G P L+ ++ + V + D ++ P F + DY F + G + + + Q+ ATD+D G G V +
Sbjct: 2393 VYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAI-----DRKTGVIRTQ----RALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVP---GNAKIGDFVGQVTATDRDSGDQGRVFF 2657 HSP 11 Score: 95.1301 bits (235), Expect = 1.325e-19 Identity = 130/545 (23.85%), Postives = 211/545 (38.72%), Query Frame = 1
Query: 904 ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRN-------------GMFECSLNDSGKLNLKNIRFDDNFAI-------YKIETYPDTSFDREKISV------YTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNN-GHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIK-NERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNP 2448
++++ A D D + NG V+Y + E + +F I+ +T ++ + + I TD + V + + D ND+PP+ + + E+ + ++T+V D DK + S D + I++ +F I YKI+ R I V + ++ +DQG P ++ I I P+F V EN +G++V VR D + G I Y+I NSN G I D E + VV+A D+ P + V + + D+ND PVF + + + E I + + A DKD G NG V + + G+ K + G I LD E I + + V+A D+G P + T ++ I VLDLNDN PVF P N V V + + + D D G N ++ ++I + F I + + ++ N L IKA+D G P
Sbjct: 2088 VVKVTATDVD--SGTNGKVTYSIWTGNE-----AGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEV-NIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKY--SFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIIIT----REPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSNYFRIGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYM---AQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQS-------GDDKGSFAIDRKT-----GVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPND--VQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQG--LFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPP 2599 HSP 12 Score: 85.8853 bits (211), Expect = 9.474e-17 Identity = 105/379 (27.70%), Postives = 163/379 (43.01%), Query Frame = 1
Query: 1378 TSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN--DNFAI--------SIYGEI---QSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITES--YGESIKNERLEQIKATDKDLGQNGTVKYRL-IDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYP-SLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEII-IAHTMKEFSNFRSLPDRLIIKAS--DLGQNPK 2451
T DREK+S Y + I V+ P S + + D+NDN+P FV VV N ++ A+D D +N Y+I++ N + F + +Y ++ S I DRE+ DSY ++A D G P + + + + ++D ND P F Y I E+ G SI Q+ A+DKD+G N ++Y + P I G + N ++ LD E S ++V+A D G LS++ + IEVLD+NDN PV V+ IG + V D D G NG + +L + + F + + II + ++ R D +KA D G P+
Sbjct: 18 TVLDREKVSAYNLTI--VEFSTPPKS--YTVLVYVQDLNDNSPSFVRGTSAKLVVFEND-KDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSIL-----QVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVR------------LDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLD-----RETHDHFFLKAVCIDKGDPPR 369 HSP 13 Score: 69.707 bits (169), Expect = 8.006e-12 Identity = 61/195 (31.28%), Postives = 86/195 (44.10%), Query Frame = 1
Query: 1084 RIYITATD-GNGRMN-ETSVDIAIEDCNDHPPVISIANRFG-KVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDT--SFDREKISVY--TVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN 1647
+ + ATD G+ M+ + SV I + D ND+PPV + +VLEN L + D D G N ++ L F I K + T +FD E +VY ++ IK D GNP +SS +N+ D ++ P F F V N IG VGQV A D DS + G + + N N
Sbjct: 2479 HVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGL--------FLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQGRVFFVFYNPTSN 2665
BLAST of Protocadherin-11 X-linked vs. Ensembl Nematostella
Match: EDO35412 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK9]) HSP 1 Score: 159.844 bits (403), Expect = 1.597e-39 Identity = 160/566 (28.27%), Postives = 253/566 (44.70%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNG--RMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNG--MFECSLNDSGKLNLKNIRFDDNFAIYKIET-----YPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSIL--NSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPD------RLIIKASDLGQNPKNNIATLYI 2475
+P +T + Y NI E G +L+L A D D+ + NG VSY ++ + F ++ +T + +++ I ITA D + T+V + I D ND+ P ++ G + E + V D D G NG +E S +D+ ++N ++++ T + + DRE S+Y+ + D G+P + S K + I D+NDNAP F ++EN P G + QV A D D N I Y I+ N+N NF+I S G I + D E + + +++A+D G + VV V + + D PVF + Y F + E+ K + ++ AT KD +NG++ Y ++ P NL V S G I + G++DREE + L V A LS T+ IEVLD NDNAP F S + V++ W +G+ + DLD G NG + + L ++ EG + I T R L D + + ASD G P+++ T++I
Sbjct: 422 SPAFTSNAYTANISELAQNGSYVLQLNATDPDEGD--NGTVSYSITGGND-----LGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDA-QVN----------GLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMENEPPGKLL-QVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVP---KGTLVGRVYATTKD--KNGSISYAIVSGDP-------------TNLFLVDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQF---STSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTSN-----------AEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHI 936 HSP 2 Score: 158.303 bits (399), Expect = 4.565e-39 Identity = 207/753 (27.49%), Postives = 322/753 (42.76%), Query Frame = 1
Query: 310 FSLNRTSGDLIVKSFLDRETICENTKETCSMKL-YLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEII--KNIDREEFVSFVFILIATDFGNQT--GSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGN--GRMNETSVDIAIEDCNDHPPVISI----------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISI---YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNL 2502
F N +G + + +DRET + S++L L+ I + ++++DINDN P F T + I+E++ + TT P+ A D D+ G Y IA G+N F + +L +I K +DRE + + ATD G G C + + + D ND+AP +T+++Y +I E G IL + A DRD + NG + Y + D + IF ++ + + + +N+ + A+DG + + +V I + D ND+ P + I A R L N IL V D+D N E + + + F Y I+ DRE + Y + + D+G P+ S++ I++ DVNDN+P F + ++ E GS V Q+ A D D +NG + YSI ND + G + + DRE+ S +TA+D+G S V V I D ND P F K ++ T S G SI L Q+ ATD D G NG + Y + S A++ L +++ G + LDRE S V A D G P L ++ + + + D+NDNAPVF +P + + +E E + V D D+G N I++ +I N NF +A E F S LII A D G A + + ++ NL
Sbjct: 42 FGFNSNTGVISTTARIDRETTTQ-----ISLQLRTLNPSNQPISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIAS-------------GDNTATFSLGTTACPTGS---TLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRD--SGSNGDIKYAID---WDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYIL----VTDKDSNTNSQTELKITNGDDEGCFKVEF---LGFYFIQL--QKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSS-YKGTISEGASIGATVL-QVSATDVDSGDNGRITYEI-----------SSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVF-YP---VEYFASIMENEPPGKLLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFS----LIISAKDGGNKYAAKTAVVNVTVLNKADNL 738 HSP 3 Score: 154.836 bits (390), Expect = 6.060e-38 Identity = 125/408 (30.64%), Postives = 184/408 (45.10%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS----NDNFAISI-YGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITESYGESIKNE---RLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMN-FVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
V I + D ND+ P + + E + + + D D+G NG S+ L + F DRE++S T+ I D G+ + ++ IID NDN PRF+ + E IG+TV QV A D+DS +NG I Y I +S N F ++ G + +K + DRE Y F V A+D+G+PQL S+ V++ I DIND PVF +YF I E NE +L Q+ ATD D G N + Y +I GN+ N S G IS +LD E L++ A D G + T + + VL+ DN PVFL+ N + NV +G+ T K K NG+I++++++ + F
Sbjct: 411 VLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQSGLVTTA------KPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIME-------NEPPGKLLQVTATDADEGTNAVISYDIIG-------GNNN-----GNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKDK------NGSISYAIVSGDPTNLF 787 HSP 4 Score: 146.362 bits (368), Expect = 2.512e-35 Identity = 162/597 (27.14%), Postives = 258/597 (43.22%), Query Frame = 1
Query: 712 LEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXX-------APEWTKDNYKVNIQECQSEGDIL-ELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNK--LHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY-GEIQSKIKFDREK----TDSYEFVVTARD--NGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNP 2448
++I ++DREE ++ +IA + G+ VN AP+++ + V+I G ++ A D D KNGLV YQL+ E + +IN + L G + + + A+D +++ I I +HPP ++++ VL +Q V D+D G+NG S+ + L I I K S + Y + ++ D G P+ S+ +I I D ND+ FVN F V EN+ G+ VG + A LD S IVYS+++S +FA+ + G+I ++++ DRE+ T S +++ A N D +V V + D+ND PVF + Y ++E S+ + +IKA D D G N Y L+ + S G + + LDRE SS L+V+A D +L +T I I V D ND PV FP ++ VN++ + IG + + D D G NG I +S+ N N F + G +I+A ++ +F + L I A D G P
Sbjct: 796 IKINGDMDREEKAQYLLAVIA-----RVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLD--AGKNGLVRYQLTSNAEG------LLWINSTSGVIKLARKLTDG--DETQYTVQVLASDSGSPPQHSTMTIHITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQGNEEGLFGIFPGGKLYIRK-------SLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSESHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSE---LSLPGSPVFRIKAMDADEGDNAKFFYSLVS------------GTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPV--FPESDYT-VNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVE-SATGRLIVAKSL-DFETTQLY--ELTITAQDHGLIP 1348 HSP 5 Score: 140.969 bits (354), Expect = 1.102e-33 Identity = 190/737 (25.78%), Postives = 320/737 (43.42%), Query Frame = 1
Query: 190 FSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYI-ARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYI-NGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAI--EDCNDHPPVISIANRFG-KVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAI----YKIETYPDTSFDREKI------SVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN--DNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKV-SFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFV---NVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
F+V EN G +VG VY+ N S S + + + + F ++ T G + + +DRE + + + + + IE+ D NDN P F T+ +++I +G A D D+ K G+ Y + + +G+ N + +++ + + + + ++A+D G+ T+T+ +T ++ P++T +Y ++ Q ++A D+D + KNG + Y + E+ +F I G KL++ + + L + + + + ATDG SV + I +D NDH + + N F V EN ++ T+ D R SL I + +FA+ +I T DRE++ +VY ++ + + + + D+NDNAP F + V E + GS V +++AMD D +N YS+++ D F I S GE+ DRE T SY VV A D L + +++ + D ND PVF E DY ITE +++ + + A+DKD+GQNG +KY + N L A + V S G + V +LD E +L + A D G LS+T + + VLD+NDNAP LFP+ + NV+ + +G+ CT D D G N I S+ + + F
Sbjct: 748 FTVYENVPKGTLVGRVYATTKD-KNGSISYAIVSGDPTNLFLVDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTSNAEGLLWINSTSGV----------------------IKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQD--SGKNGQLFYSIPQGNEE-----GLFGIFPGGKLYIRKSLLQAL--KGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLF-VNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSL----------ISSESHFAVDVRSGQITTR--VRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITE---DALIGSLVINLNASDKDIGQNGLIKYSI---------SNGNLAA----MFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAP--LFPTQPVTLTVRENVNTGFPVGR--CTA--SDRDTGTNAHIAFSMYSQTPSKTF 1417 HSP 6 Score: 128.642 bits (322), Expect = 5.726e-30 Identity = 126/445 (28.31%), Postives = 196/445 (44.04%), Query Frame = 1
Query: 1135 VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAI--YKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAI-----SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNE-RLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPE-GEIIIAHTMKEFSNFRSLPDRLIIKASDLGQ 2442
V + + D ND+ PV S A V E + ++ D D+G N F SL + D F I E + + DRE S Y + +K D N + S K I + D ND P F ++ E+ IGS V + A D D NG I YSI SN N A S G + D E T YE +TA+D+G L+ ++ V V + D+ND P+F +T + E++ + + A+D+D G N + + + P + E+ + + + ++ D S QL+V A D G P LST +I ++V D NDN+P F+ P +++V T+ +D D+ NG +T+S+I+ N N F + P G++ + H + + +L I+ASD GQ
Sbjct: 1145 VIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGM--------DKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSI--SNGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQ---PVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEITTIAAIDLE---TMPAGRD-----SFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPAAAAGSSLNV--------MTITAEDPDRNSNGKVTYSIISGN---NGYFNLHPSTGQLQMIHQIPDNPTIY----QLTIQASDGGQ 1553 HSP 7 Score: 109.768 bits (273), Expect = 4.237e-24 Identity = 132/512 (25.78%), Postives = 217/512 (42.38%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGD-ILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGN--KLHLTNNRISGLINRNNIRIY---ITATDG-NGRMNETS-VDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYG---EIQSKIKFDREKT----DSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEI-GKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
AP +++ Y + + E G + + A D D+ + N Y L T K F+IN + +LHL S ++R Y + ATD N + T+ ++I + D ND PV ++ + E+ ++ + D+D G+NG+ + S+++ NL + FD A ++ S D E +Y + I D G +SS ++N++DVNDNAP F + V EN G VG+ A D D+ N HI +S+ + + S+ EI + D E DS++ VV A D G P+L+ + V++ D ND +P F ++ + + + I A D D NG V Y +I G G L L ++ D I QL +QA D G PS T T + + P F ++ ++ E ++ G ++ TV +NG I + L + + + F
Sbjct: 1156 APVFSRAVYAITVSELSLPGSPVFRIKAMDADEGD--NAKFFYSLVSGTGMDK-----FFINSSTGELHL-----SKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNG---NLAAM-FDVESATGRLIVA--KSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGF-------VSPPAAAAGSSLNVMTITAEDPDRNSNGKVTYSIIS----GNNGYFNLHPSTGQLQM--------IHQIPDNPTI--YQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTF----SSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGGF 1624 HSP 8 Score: 53.9138 bits (128), Expect = 4.101e-7 Identity = 130/531 (24.48%), Postives = 218/531 (41.05%), Query Frame = 1
Query: 277 SLMKANEKDSYFSLNRTSGDLIVKSFLDRET-----ICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFG--NQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGL----INRNNIRIYITATD-GNGRMN-ETSVDIAIEDCNDHPP--VISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSL--NDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY---GEIQSKIKFDREKTD-SYEFVVTARDNGEPQL-NDSMVVKVKIQDIN 1800
SL+ D +F +N ++G+L + LDRET + + + LY +I I + D ND PVF + +NI E+ IG+ A DKD + G+ Y I+ GN F +++ + L + K++D E + + A D G + + VTV V DVNDNAP + + ++E + G + A+DRD N +++ + +T S+ F +N +T L R++ ++ + ATD G+ +++ S+ + + D ND+ P V A G L + T+ +D D+ NG S+ ++G NL + I PD ++Y + I+ D G P+ + S+ P F + V EN G++V V A SS NG+I Y + + + + G +++ DRE S+ VV A D P S V + +QD+N
Sbjct: 1197 SLVSGTGMDKFF-INSSTGELHLSKTLDRETTSSYNLVVKATDASNANLY-----STAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISN-------------GNLAAMFDVESATGR-------LIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRD--TGTNAHIAFSMYSQTP-----SKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPAAAAGSSLN-------VMTITAEDPDRNSNGKVTYSIISGNNGYFNLH----PSTGQLQMIHQIPDNP------TIYQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGGFEVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677
BLAST of Protocadherin-11 X-linked vs. Ensembl Nematostella
Match: EDO25673 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DVT6]) HSP 1 Score: 143.665 bits (361), Expect = 2.320e-37 Identity = 119/372 (31.99%), Postives = 179/372 (48.12%), Query Frame = 1
Query: 1369 YPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILN-SNDNFAIS-IYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMV-VKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLI---DVKPIGIPGNSKL-KAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYP-SLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKI-QPEGEIIIAHTM--KEFSNFRSLPDRLIIKASDLGQNP 2448
Y +FDRE Y++ + D GNP+ SS + + D NDN+P+F +F + E+ +G+++G V A D D N + YSI++ F+++ + GEI + DRE + Y VTA DNG ND+ V V + + D+ND P FE Y I+ES + K + +KA DKD G NG VKY LI D I GN + AE+ LDRE+ S+ L V+A D L T ++I V D+ND P F S +VS +G + TV D D+G NG + +SL PF + +G + ++ +M ++ +N+ + + A+DLG P
Sbjct: 6 YTTGTFDRETKDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSIVSPEKATFSMNPVTGEITVGQRLDREGVEHYLLNVTATDNGRLNTNDASVDVYINVLDVNDNAPQFEAAVYHGEISES---ADKLTPIVTVKAIDKDSGSNGIVKYSLISGNDGDAFTILGNGTIVNAEV-----------------LDREKKSTYNLEVRAVDQATSGGLEGVTRVVINVTDVNDQPPEFTSAS----VAHVSENSRVGDVVLTVIAVDADEGSNGDVVYSL---GLDIGAPFSLGSKDGVLRVSGSMDREKKANY-----SIRVTATDLGTPP 345 HSP 2 Score: 110.538 bits (275), Expect = 3.872e-26 Identity = 114/364 (31.32%), Postives = 176/364 (48.35%), Query Frame = 1
Query: 733 DREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLI------NRNNIRIY---ITATDGNGRMN--ETSVDIAIE--DCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSL---NDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQG-NPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI-LNSNDNFAI-SIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLN 1761
DRE + + A+D GN ++ +C V V V D NDN+P++ +Y +I E + G + G VS +D E+ ++ I ++ K + N ++G I +R + Y +TATD NGR+N + SVD+ I D ND+ P A G++ E+ + + TV+ D+D G NG+ + SL ND + N I E DREK S Y +E++ VDQ + + + + IN+ DVND P F + + HV EN+ +G V V A+D D +NG +VYS+ L+ F++ S G ++ DREK +Y VTA D G P L+
Sbjct: 12 DRETKDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAVGASI--------------GTVSASDADIGENARLTYSI--VSPEKATFSMNPVTGEITVGQRLDREGVEHYLLNVTATD-NGRLNTNDASVDVYINVLDVNDNAPQFEAAVYHGEISESADKLTPIVTVKAIDKDSGSNGIVKYSLISGNDGDAFTILG-----NGTIVNAEV-----LDREKKSTYNLEVRAVDQATSGGLEGVTRVVINVTDVNDQPPEFTSA-SVAHVSENSRVGDVVLTVIAVDADEGSNGDVVYSLGLDIGAPFSLGSKDGVLRVSGSMDREKKANYSIRVTATDLGTPPLS 347 HSP 3 Score: 98.9821 bits (245), Expect = 3.863e-22 Identity = 102/357 (28.57%), Postives = 162/357 (45.38%), Query Frame = 1
Query: 1072 RNNIRIYITATD-GNGRMNETSVD-IAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQG--NPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYG--EIQSKIKFDREKTDSYEFVVTARDNG-EPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRL-IDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLS 2118
+++ I +TA+D GN + T V + + D ND+ P + + E+ + TV D D G N S+ ++ + F N +I DRE + Y + + D G N +S+ + IN++DVNDNAP+F + + E+ + + V+A+D DS +NG + YS+++ ND A +I G I + DREK +Y V A D L V + + D+ND P F ++E+ S + + + A D D G NG V Y L +D IG P + K DG + V G++DRE+ ++ + V A D G P LS
Sbjct: 16 KDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSI-----VSPEKATFSMNPVTGEITV--GQRLDREGVEHYLLNVTATDNGRLNTNDASVDVY-INVLDVNDNAPQFEAAVYHGEISESADKLTPIVTVKAIDKDSGSNGIVKYSLISGNDGDAFTILGNGTIVNAEVLDREKKSTYNLEVRAVDQATSGGLEGVTRVVINVTDVNDQPPEFTSASVAHVSEN---SRVGDVVLTVIAVDADEGSNGDVVYSLGLD---IGAPFSLGSK-----------DGVLRVSGSMDREKKANYSIRVTATDLGTPPLS 347 HSP 4 Score: 87.4261 bits (215), Expect = 2.820e-18 Identity = 82/261 (31.42%), Postives = 124/261 (47.51%), Query Frame = 1
Query: 1666 GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEK-DYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLS-TTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTM-KEFSNFRSLPDRLIIKASDLG 2439
G I + FDRE D Y VTA D+G P + + VV V + D ND +P F Y F I E ++ + + A+D D+G+N + Y ++ S KA ++ V+ G I+V LDRE + L V A D+G + + + + I VLD+NDNAP F + +S + I TVK D D G NG + +SLI+ N + F I G I+ A + +E + +L R + +A+ G
Sbjct: 3 GRIYTTGTFDRETKDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAE---DAAVGASIGTVSASDADIGENARLTYSIV----------SPEKATF-SMNPVT--GEITVGQRLDREGVEHYLLNVTATDNGRLNTNDASVDVYINVLDVNDNAPQF---EAAVYHGEISESADKLTPIVTVKAIDKDSGSNGIVKYSLISGNDGD--AFTILGNGTIVNAEVLDREKKSTYNLEVRAVDQATSGG 242
BLAST of Protocadherin-11 X-linked vs. Ensembl Medaka
Match: PCDH17 (protocadherin-17 [Source:NCBI gene;Acc:101168002]) HSP 1 Score: 211.846 bits (538), Expect = 1.336e-55 Identity = 212/718 (29.53%), Postives = 330/718 (45.96%), Query Frame = 1
Query: 124 MLIELDILIIFSIKLVITLNVEFSVDENCRIGHVVGNV-----YSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICE-NTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDIL-ELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNN---IRIYITATD--GNGRMNETSVDIAIEDCNDHPPVIS-IANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRF-----DDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY---------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNER-------LEQIKATDKDLGQNGTVKY--------RLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEV 2145
M + + I + +K + N+ +SV E G V+GN+ Y + + S+ L N ++ SG + K +DRET+C N K SM+++ + D I I+I DINDN P F + I+I EN GT +PL +A D DS + G+KTY + R +++ F + IYP L + + +DRE+ +L A D G ++GS + V VTD NDN+P + K +Y + I E G IL +L A D+D+ NG V Y + +R + +F I+ N + ++ G I+ I + A D N + + ++D ND+ PVI+ ++ R G + E ++ V+V D+D GRNG +C + L N+ F +DNF Y + T D DRE Y V I D G P++++ + F++ I+D NDNAPRF + + V ENN G +G + A D D NG + YSIL S+ +S+Y G I + F+ E+T S+EF V A+D G P + + V+V I D+ND PV + ++ I R + +KA D D G +G + Y L ++ P+G G + L E ++L+V+ D G P LS +II+V
Sbjct: 1 MRLSVPIFFLLWVKALSLKNLNYSVPEEQGPGTVIGNIAKDAGYGTIERGKKSNFRVL--ENSAPHLVDVDPESGLIFTKQRIDRETLCRRNPKCQLSMEVFAN-DKEICMIKIDIQDINDNSPSFPSDHVNIDISENAAAGTRFPLTIAHDLDSGENGIKTYQVTR--------------DDYNTFSLDLKVRGDGTIYPELVVQRPLDREDQSHHTLLLTAIDGGEYPRSGSMQINVRVTDSNDNSPVFEKSSYVIEIPENLPPGKILIDLNATDQDE--GSNGQVVYSFTGYASER--IQDLFSIDPNTGVI---KVQGEIDFEENPIIEFDVQAKDLGPNPIPGHCKITVKVQDKNDNSPVITFVSVRQGAISEAAPPDSVIALVRVTDKDSGRNGQLQCRV-------LGNVPFRLQENNDNF--YTLLT--DRPLDRETRDEYNVTIVARDNGIPSLNNTRSFTVKILDENDNAPRFTKSLYVLQVPENNIPGEYLGSILAHDPDVGRNGTVTYSILPSHIG-DVSVYTYVSVNPTNGAIYASRSFNYEQTKSFEFKVQAKDGGSPHMESTSTVRVNILDVNDNLPVI----ILPLLQNDTAEIPVPRNVGIGYIVATVKAVDHDHGDSGHLTYEITEGNDDHLFEIDPVG--------------------GEVRTAHALWEEIAPVVELVVRVTDHGKPPLSAVAKLIIKV 658 HSP 2 Score: 176.407 bits (446), Expect = 2.151e-44 Identity = 161/588 (27.38%), Postives = 275/588 (46.77%), Query Frame = 1
Query: 841 APEWTKDNYKVNIQECQSEGDILEL-IANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKL---HLTNNRISGLINRNNIRIYITATDGN--GRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNI-RFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAP--RFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS--------NDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVS-FDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP--SNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQP-EGEIIIAHTM-KEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRY-IHSLTNLNPTSIGKKSH 2532
+P + D+ ++I E + G L IA+D D + +NG+ +YQ++ +D S + G+ L R ++++ + +TA DG R +++ + D ND+ PV ++ ++ EN IL + D+D+G NG S ++++ D N + K++ D E+ + +++ D G + K ++ + D NDN+P FV+ ++ + E P S + VR D DS NG + +L + NDNF + + DRE D Y + ARDNG P LN++ VKI D ND P F K Y ++ E+ +I E L I A D D+G+NGTV Y ++ IG + + V+ +GAI + + E+ S + VQA D G P + +T+T+ + +LD+NDN PV + P N+ + V IG + TVK D D G +G +T+ + N ++ F+I P GE+ AH + +E + L+++ +D G+ P + +A L I+ + ++ G+K H
Sbjct: 120 SPSFPSDHVNIDISENAAAGTRFPLTIAHDLD--SGENGIKTYQVT--RDDYNTFSLDLKVRGDGTIYPELVVQRPLDREDQSHHTLLLTAIDGGEYPRSGSMQINVRVTDSNDNSPVFEKSSYVIEIPENLPPGKILIDLNATDQDEGSNGQVVYSFTGYASERIQDLFSIDPNTGVIKVQG----EIDFEENPIIEFDVQAKDLGPNPIPGHCKITVKVQDKNDNSPVITFVS-VRQGAISEAAPPDSVIALVRVTDKDSGRNGQLQCRVLGNVPFRLQENNDNFYT-----LLTDRPLDRETRDEYNVTIVARDNGIPSLNNTRSFTVKILDENDNAPRFTKSLYVLQVPEN---NIPGEYLGSILAHDPDVGRNGTVTYSILPSH-IG-------DVSVYTYVSVNPTNGAIYASRSFNYEQTKSFEFKVQAKDGGSPHMESTSTVRVNILDVNDNLPVIILPLLQNDTAEIPVPRNVGIGYIVATVKAVDHDHGDSGHLTYEITEGN--DDHLFEIDPVGGEVRTAHALWEEIAPVV----ELVVRVTDHGKPPLSAVAKLIIKVNTETAVGGGSSASGEKQH 676
BLAST of Protocadherin-11 X-linked vs. Ensembl Medaka
Match: pcdh1b (protocadherin-1 [Source:NCBI gene;Acc:101174755]) HSP 1 Score: 210.305 bits (534), Expect = 2.909e-55 Identity = 200/696 (28.74%), Postives = 320/696 (45.98%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINR---NNIRIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTN 2499
F + ++I EN GT + +PVA D+DS GV Y A G D Q F ++ + E+I P + +I N+DRE+ S+ + D G + S + + VTD NDNAP++ K+ Y+ + E G +L++ AND D NG + Y L ++ V ++ I+ + + + GL++R N ++ Y+ A D N + ++ V I+I+D ND+ P I I N + E+ + VQV D D+G N + C + L+ N K T D E+I Y +EI VD GNPA+SS + + D+NDN P F + + E+N G V V A D DS N +VYSI+ S+ A S++ GEI+ + + DRE + YEF V A D G P + +V + ++D ND P F Y F + E+ + + +D D G+N V + P N K I + G I + DRE+ S+ ++A D G P S+ + I VLD NDNAP P+N+ ++ ++ + VK +D+D G+N + +++ N F GEI +A + F+ RL+++ SD G+ P++ A +++ Y++ TN
Sbjct: 151 FSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEY--ALSAGPDAN----------QLFGLQVAEDVDEKI-PQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDAD--TGANGDIDYSLHQASD---TVQRLLRIDRSTGII---YVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESS---AASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPL---NPVGVVTVSDADKGENSQVTLFV-------EPDNGK-------FIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANS-SYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGNPHGLFQIS-HNSGEIKLA---QGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHV-YVNETTN 799 HSP 2 Score: 130.954 bits (328), Expect = 2.532e-30 Identity = 117/410 (28.54%), Postives = 188/410 (45.85%), Query Frame = 1
Query: 1141 IAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLN---DSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY-----GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNER-----LEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
I + D ND+ P S + EN + + D D G NG+ E +L+ D+ +L + D + I ++ + DREK Y + I+ VD G P +S I + D NDNAP+F + EN+P G +V QVRA D D+ NG I YS+ ++D + G I K DRE+ + +F V ARD G + V + I+D ND P E + I +++ +I + + ++ +D+D G+N V V +P + +E N K + + LD E I ++ + A D G P+LS+T ++ ++V D+NDN P F S + VN + + + G + V D D G+N + +S+I S+ F
Sbjct: 139 IEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIVI--GNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASDTVQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTC----VVAGDVPFQLRPASESANDRKRKY--FLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSF---SPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASLF 537 HSP 3 Score: 119.398 bits (298), Expect = 8.032e-27 Identity = 97/334 (29.04%), Postives = 155/334 (46.41%), Query Frame = 1
Query: 1474 INIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISIYGEIQSKIK-------FDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNM----NFV-NVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIK 2424
I ++D+NDN P+F + I + EN G+ A+D DS +NG Y++ ++N F + + ++ KI DREK DSY+ + D G+P S ++++ + D ND P FEK+ Y + E+ S + Q++A D D G NG + Y L + ++ L+++ G I V G +DREE + ++ V A D G S S+ + I + D NDNAP + NFV N+S + IG + V+ D D+G N +T + + PF+++P E K F +L D IK
Sbjct: 139 IEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPEN---SPPGHSVLQVRANDADTGANGDIDYSL-----------HQASDTVQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAG-----DVPFQLRPASESANDRKRKYFLQTTTLLDYERIK 453
BLAST of Protocadherin-11 X-linked vs. Ensembl Medaka
Match: ENSORLT00000041785.1 (protocadherin gamma-C5 [Source:NCBI gene;Acc:101169865]) HSP 1 Score: 210.305 bits (534), Expect = 3.511e-55 Identity = 210/697 (30.13%), Postives = 331/697 (47.49%), Query Frame = 1
Query: 154 FSIKLVITLNVEFSVDENCRIGHVVGNVYSKLN-QLPNSSRSSLMKANEK-DSYFSLNRTSGDLIVKSFLDRETICENTKETC--SMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDI-LELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIY---ITATD-GNGRM-NETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN-DNFAISIY-------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLE----------QIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVS-FDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLD 2151
F + I +S+ E + G VVGN+ L L S +L A+E + YFS++ G+L+V +DRE +C + +C ++++ +D+ ++ +EI DINDN PVF +++K + I E+ GT +PL A D D V++Y +++ +++ +K+ ++ P L + K +DRE+ + + A D GN ++G + + V D NDN P + K+ YKV + E + I L+L A D DD NG V Y +T D V +F IN + + R+ G ++ Y ++ATD G +M SV I + D ND+ P I + ++ V EN ++ + +D D G NG + S LK F DN+A+ + DRE S Y+VEI D G+P +S+ + S+ I DVNDN P F + ++ EN GS + V A DLDSS N I YSIL+S + ++S Y G I S FD EK +E V A+D G P L+ + V V I D ND P + + + G S+ ++R+ ++ A D D G N + YRL + A +L VS + G + + ++ SS +L+++ DDG P S T T+ I + D
Sbjct: 39 FLLWSTIDAQTRYSIPEEVKHGSVVGNLAKDLGLTLTEISERALRVASESGEQYFSVDAGRGELLVNDRIDREALCRQSA-SCVLTLQVVIDKPLQLFKVEVEIIDINDNSPVFPSSEKNLQIAESTAAGTRFPLDTALDLDVGVNSVRSYTLSK--------------DDYFSLNVKDMAGGRKN--PELVLSKTLDREKMPTHQLTITAVDGGNPNKSGISQINIYVLDNNDNFPVFEKNVYKVTLSENSEKSSIVLKLAAKDSDD--GVNGEVEYSFGPQTPD--AVLSVFGINKDSGEI---RLIGNLDFETTSSYEIDVSATDKGTPKMEGHCSVHIEVLDVNDNAPYIFLTSQPNSVPENAPSGTVVALISARDLDSGDNGKVTLQVPKSSPFKLK-ASFSDNYALIT-----SRALDRETFSEYSVEITATDLGSPPLSNKKMISVTITDVNDNPPVFTQRSYNVYLKENGVPGSILFSVSASDLDSSENAKISYSILDSKVQDVSVSSYVYMNSENGSIYSMHSFDYEKLKVFEIHVQAKDQGSPSLSSNATVHVFILDQNDNAPAV----IYPSSAALG-SLSHQRMPRSAKAGHLVTKVTAVDADSGHNAWISYRLAE-------------ATDASLFTVSLYTGEVRTKRAVSEQDDSSQRLILEIKDDGEPLQSATVTVSILLED 687 HSP 2 Score: 152.14 bits (383), Expect = 6.239e-37 Identity = 138/484 (28.51%), Postives = 222/484 (45.87%), Query Frame = 1
Query: 1084 RIYITATDGNGRMNETSV---DIAIEDCNDHPPVISIANRFGKVL-ENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYK--IETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSN---------DNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVF-EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSN----NMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYI 2475
++ ITA DG G N++ + +I + D ND+ PV N + L EN ++ I+ + KD D G NG E S + ++ F I K E + D E S Y +++ D+G P M I ++DVNDNAP + V EN P G+ V + A DLDS +NG + + S+ DN+A+ I S+ DRE Y +TA D G P L++ ++ V I D+ND PVF ++ Y + E+ + L + A+D D +N + Y ++D K + +S + N G+I + D E++ ++ VQA D G PSLS+ T+ + +LD NDNAP ++PS+ +++ + + G + V D D G N I++ L + F + GE+ T + S RLI++ D G+ ++ T+ I
Sbjct: 227 QLTITAVDG-GNPNKSGISQINIYVLDNNDNFPVFE-KNVYKVTLSENSEKSSIVLKLAAKDSDDGVNGEVEYSFGPQTPDAVLSV-----FGINKDSGEIRLIGNLDFETTSSYEIDVSATDKGTPKMEGHCSVHIEVLDVNDNAPYIFLTSQPNSVPENAPSGTVVALISARDLDSGDNGKVTLQVPKSSPFKLKASFSDNYAL-----ITSR-ALDRETFSEYSVEITATDLGSPPLSNKKMISVTITDVNDNPPVFTQRSYNVYLKEN---GVPGSILFSVSASDLDSSENAKISYSILDSKVQDVSVSSYVYMNSEN-------GSIYSMHSFDYEKLKVFEIHVQAKDQGSPSLSSNATVHVFILDQNDNAPAVIYPSSAALGSLSHQRMPRSAKAGHLVTKVTAVDADSGHNAWISYRLAEATDASLFTVSLY-TGEV---RTKRAVSEQDDSSQRLILEIKDDGEPLQSATVTVSI 683 HSP 3 Score: 61.2326 bits (147), Expect = 5.845e-9 Identity = 56/179 (31.28%), Postives = 84/179 (46.93%), Query Frame = 1
Query: 1774 VKVKIQDINDCTPVF---EKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSL 2301
V+V+I DIND +PVF EK+ +I ES + R A D D+G N Y L + ++++ + + + LDRE++ + QL + A D G P+ S + I I VLD NDN PVF N+ V +S E + + KD D G+NG + +S
Sbjct: 137 VEVEIIDINDNSPVFPSSEKN--LQIAES---TAAGTRFPLDTALDLDVGVNSVRSYTLSK--------DDYFSLNVKDMAGGRKNPELVLSKTLDREKMPTHQLTITAVDGGNPNKSGISQINIYVLDNNDNFPVF---EKNVYKVTLSENSEKSSIVLKLAAKDSDDGVNGEVEYSF 299
BLAST of Protocadherin-11 X-linked vs. Ensembl Medaka
Match: pcdh1b (protocadherin-1 [Source:NCBI gene;Acc:101174755]) HSP 1 Score: 209.92 bits (533), Expect = 8.219e-55 Identity = 200/696 (28.74%), Postives = 320/696 (45.98%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINR---NNIRIYITATD--GNGRMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTN 2499
F + ++I EN GT + +PVA D+DS GV Y A G D Q F ++ + E+I P + +I N+DRE+ S+ + D G + S + + VTD NDNAP++ K+ Y+ + E G +L++ AND D NG + Y L ++ V ++ I+ + + + GL++R N ++ Y+ A D N + ++ V I+I+D ND+ P I I N + E+ + VQV D D+G N + C + L+ N K T D E+I Y +EI VD GNPA+SS + + D+NDN P F + + E+N G V V A D DS N +VYSI+ S+ A S++ GEI+ + + DRE + YEF V A D G P + +V + ++D ND P F Y F + E+ + + +D D G+N V + P N K I + G I + DRE+ S+ ++A D G P S+ + I VLD NDNAP P+N+ ++ ++ + VK +D+D G+N + +++ N F GEI +A + F+ RL+++ SD G+ P++ A +++ Y++ TN
Sbjct: 151 FSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEY--ALSAGPDAN----------QLFGLQVAEDVDEKI-PQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDAD--TGANGDIDYSLHQASD---TVQRLLRIDRSTGII---YVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESS---AASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPL---NPVGVVTVSDADKGENSQVTLFV-------EPDNGK-------FIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANS-SYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGNPHGLFQISHN-SGEIKLA---QGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHV-YVNETTN 799 HSP 2 Score: 130.568 bits (327), Expect = 3.343e-30 Identity = 117/410 (28.54%), Postives = 188/410 (45.85%), Query Frame = 1
Query: 1141 IAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLN---DSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY-----GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNER-----LEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENF 2328
I + D ND+ P S + EN + + D D G NG+ E +L+ D+ +L + D + I ++ + DREK Y + I+ VD G P +S I + D NDNAP+F + EN+P G +V QVRA D D+ NG I YS+ ++D + G I K DRE+ + +F V ARD G + V + I+D ND P E + I +++ +I + + ++ +D+D G+N V V +P + +E N K + + LD E I ++ + A D G P+LS+T ++ ++V D+NDN P F S + VN + + + G + V D D G+N + +S+I S+ F
Sbjct: 139 IEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIVI--GNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASDTVQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTC----VVAGDVPFQLRPASESANDRKRKY--FLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSF---SPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASLF 537 HSP 3 Score: 120.168 bits (300), Expect = 6.017e-27 Identity = 97/334 (29.04%), Postives = 155/334 (46.41%), Query Frame = 1
Query: 1474 INIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI---LNSNDNFAISIYGEIQSKIK-------FDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKD-YFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFD-GAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNM----NFV-NVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIK 2424
I ++D+NDN P+F + I + EN G+ A+D DS +NG Y++ ++N F + + ++ KI DREK DSY+ + D G+P S ++++ + D ND P FEK+ Y + E+ S + Q++A D D G NG + Y L + ++ L+++ G I V G +DREE + ++ V A D G S S+ + I + D NDNAP + NFV N+S + IG + V+ D D+G N +T + + PF+++P E K F +L D IK
Sbjct: 139 IEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPEN---SPPGHSVLQVRANDADTGANGDIDYSL-----------HQASDTVQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAG-----DVPFQLRPASESANDRKRKYFLQTTTLLDYERIK 453
BLAST of Protocadherin-11 X-linked vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 206.068 bits (523), Expect = 5.759e-54 Identity = 200/706 (28.33%), Postives = 318/706 (45.04%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGN--QTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEG-DILELIANDRDDPNTKNGLVSYQLSDRTE--------DRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNG--RMNETSVDIAIEDCNDHPPVISI--------ANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIR--FDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY------GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFE-KDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQP-EGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLN 2505
F + I++ EN +G + +P+A D+DS + GV Y A G D F ++ + ++ P L ++ N+DRE S+ + A D GN + + V+VTD NDN+P++ +Y+ + E G +L++ A+D D NG + Y L + DR + I Y+ G L I N++ Y+ A D + ++T V I + D ND+ P + I + + E+ + VQV D+D+G N + C + L+ DN Y ++T T D E++ Y VEI VD GNPA+SS + + DVNDN+P F I E N G T+ V A D DS N + Y+I+ D++ ++ GE++++ DRE + YEF VTA D G P + V +K+ D ND P F Y F + E+ + + D D G+N V + V+P G + + G I + DRE+ SS ++A D G P S+ + I VLD NDN PV PSN+ +F +S + V+ +DLD G N + S+ N + F+I P GEI +A KE + RL+++ SD G+ P++ A ++I +++N++
Sbjct: 132 FPLSVLTISVPENTIMGALFSIPLATDRDSERNGVADY--ALTAGPDAAT----------LFGLQVADDRGGKL-PQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSD--MGPNGEIEYSLHQAVDPVPKLLRIDR--TTGIIYVKGP---LDREEI------NSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYFLQTT--TPLDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIV--GDSYIKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPL---SPVGMVTVLDMDKGENAHVH---LSVEPDG-----------GKFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKPSNS-SFRQLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGNPYQL--FRISPSSGEITLA---KEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYVNETISNVS 784 HSP 2 Score: 140.198 bits (352), Expect = 3.412e-33 Identity = 128/468 (27.35%), Postives = 206/468 (44.02%), Query Frame = 1
Query: 1141 IAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLN---DSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIY-----GEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERL------EQIKATDKDLGQNGTVKYRLIDVKPIGI-PGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHT-----MKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYI 2484
I ++D ND+ P ++ V EN + + D D RNG+ + +L D+ L + D + ++ + DRE Y + IK VD GNP S + + D NDN+P+F + V EN+P+G +V QV+A D D NG I YS+ + D + G I K DRE+ +S F V ARD G + V +++ D ND P E +T S G + +E + ++ +DKD G+N V + P + P + R + LD E + ++ + A D G P+LS+T ++ ++V D+NDN+PVF S + V+ + E + G+TI V D D G N + ++++ + + F+I P + A T KE FR + A+D G AT+ I+ +
Sbjct: 120 IEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVL--GNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGIIYVKGPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYF-------LQTTTPLDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVF---SPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYIKGL-FEIDPNTGEVKARTPLDREHKERYEFR-------VTAADKGSPVHKGTATVVIKVL 567 HSP 3 Score: 71.2478 bits (173), Expect = 4.740e-12 Identity = 83/278 (29.86%), Postives = 120/278 (43.17%), Query Frame = 1
Query: 1528 MFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEI-QSKIKFDRE-----------KTDSYEFVVTARD---NGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIK-ATDKDLGQNGTVKYRLI---DVKPI-GIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSL 2301
++ V E P + +G + A D ++GH+ + + G+I ++I DRE K EF V+ D N P+L + ++++QDIND TP F +T S E+ L I ATD+D +NG Y L D + G+ +L LI V GNLDRE S L ++A D G P + + + V D NDN+P F PS VS +G ++ VK D D G NG I +SL
Sbjct: 25 LYRVQEEQPPNTLIGSL-AADHGLPDSGHLYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLRDCRSLVKGKPCYLEFEVSVTDLLQNPSPRLIEG---RIEVQDINDNTPQFP---LSVLTISVPENTIMGALFSIPLATDRDSERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLI---------VLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYE---AEVSENSPVGHSVLQVKADDSDMGPNGEIEYSL 283
BLAST of Protocadherin-11 X-linked vs. Planmine SMEST
Match: SMESG000066775.1 (SMESG000066775.1) HSP 1 Score: 2056.57 bits (5327), Expect = 0.000e+0 Identity = 1059/1065 (99.44%), Postives = 1061/1065 (99.62%), Query Frame = 1
Query: 124 MLIELDILIIFSIKLVITLNVEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNLNPTSIGKKSHSSDNNNFGFRLKNDNKNPISTKNFNPNLSDSMMVLYSLAAXXXXXXXXXXXXXXXXYWSKHYSVNDRYSKKIYKAGNVQLDLDTNLKEMKNVTKSIRSNRDCETSGNEDASAVCFIGDDGSSYTHLMMLSNSKYTPMLHNPGSPGSLRQIVNNKNFHQSSVENNLINYSENLINPSSYMPPISCPSKARMKGFSTSISYNSDKEGENYSTLKDKINVDFNALNIDRNVHTISIASHNNPQENPDFCQKPRDFNSPYVTSSFV 3318
M IELDILIIFSIKLVITLNVEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAIQIVIEINDINDNVPVFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIA DFGNQTGSCTVTVLVTDVNDNAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAIS+YGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQ EGEIIIAH+MKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTN NPTSIGKKSHSSDNNNFGFRLKNDNKNPISTKNFNPNLSDSMMVLYSLAAILFFIFLIVLFVLVFIYWSKHYSVNDRYSKKIYKAGNVQLDLDTNLKEMKNVTKSIRSNRDCETSGNEDASAVCFIGDDGSSYTHLMMLSNSKYTPMLHNPGSPGSLRQIVNNKNFHQSSVENNLINYSENLINPSSYMPPISCPSKARMKGFSTSISYNSDKEGENYSTLKDKINVDFNALNIDRNVHTISIASHNNPQENPDFCQKPRDFNSPYVTSSFV
Sbjct: 1 MFIELDILIIFSIKLVITLNVEFSVDENCRIGHVVGNVYSKLNQLPNSSRSSLMKANEKDSYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAIQIVIEINDINDNVPVFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIAADFGNQTGSCTVTVLVTDVNDNAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISIYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQSEGEIIIAHSMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIHSLTNSNPTSIGKKSHSSDNNNFGFRLKNDNKNPISTKNFNPNLSDSMMVLYSLAAILFFIFLIVLFVLVFIYWSKHYSVNDRYSKKIYKAGNVQLDLDTNLKEMKNVTKSIRSNRDCETSGNEDASAVCFIGDDGSSYTHLMMLSNSKYTPMLHNPGSPGSLRQIVNNKNFHQSSVENNLINYSENLINPSSYMPPISCPSKARMKGFSTSISYNSDKEGENYSTLKDKINVDFNALNIDRNVHTISIASHNNPQENPDFCQKPRDFNSPYVTSSFV 1065
BLAST of Protocadherin-11 X-linked vs. Planmine SMEST
Match: SMESG000007877.1 (SMESG000007877.1) HSP 1 Score: 543.117 bits (1398), Expect = 1.784e-174 Identity = 372/953 (39.03%), Postives = 565/953 (59.29%), Query Frame = 1
Query: 175 TLNVEFSVDENCRIGHVVGNV--YSKLNQLP-NSSRSSLMKANEKD--SYFSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLDQDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIA--RCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSG-----KLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--FAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRE-NFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYI-HSLTNLN---PTSIGKKSHSSDNNNFGFRLKNDNKNPISTKNFNPNLSDSMMVLYSLAAXXXXXXXXXXXXXXXXYWSKHYSVNDRYSKKIYKAGNVQLDLDTNLKEMKNVTKSIRSNRDCE------TSGNED-----ASAVCFIGDDGSSYTHLMMLSNSKYTPM 2943
T ++ + EN G + N+ Y +++LP NSS + + +NE D +YF L SG L ++ +DRET+C++ + C + + + ++++++IND NDN+P F K ++IQEN IG+ LP A D DS + Y+I + I + NQ + ++F I + +I P L++IK IDREE F ILIA D G Q GSCT+TV + DVNDN+P+W N ++EC +G ++EL A DRDD +T NG + Y++SD + +++++++FYI G+ L L++ + + + I +ITA DG GR N T+V I IEDCNDH P I+I + EN + ++LT+V V D+DKG N F C LND+ K ++ N +Y I+ PDT FDRE +S Y+V I+C+D G P + + F++ IID NDNAP+F + F + ENN IG+ +G VRA D DS+ NG + Y ILN+++N F I+I G+I++K KFDRE D Y + A+DNGEP LND+ V ++I D+NDC PVF++ YF++ITE G + + L ++ A DKDLG+NGTV Y ++ N + L NL+K++ +G +++YG +DRE++ SIQ + A+D+G P LS +I++VLD+NDN P F +P N MNF+N+S + ++GK + + +D D+G NGTIT+S+I+ E N P+++Q +G +I+ ++E R LPDRLII+ASD G PK + T+ IRYI ++LT N P I KKS+ D N F ++ ++ ST D+M +LY L ILF +F+IVL VLV+ Y+S +S + QLDL T+ KE+ N N +C+ S +ED ++ D ++YTHLM ++ +KYTP+
Sbjct: 6 TFYIKLKISENKGSGEDLINLKNYIIIHKLPINSSGTYNIISNEPDINNYFILQSHSGILKQRNNIDRETMCKHA-DVCQKIILISINGQVLEVMVDINDENDNIPQFSMRHKTLSIQENSDIGSELSLPTADDLDSEPNSIIRYFIKDIHSRDIRRMNQFQA----SRYFTIFIKTMNRMKI-PYLKLIKEIDREEIDRFELILIAEDSGKQQGSCTITVSIIDVNDNSPQWPTVNISKTVKECDRQGPLVELQAFDRDDSSTPNGQIKYKISDNSPKKELINRLFYIAGSSLFLSSQGLQLMDLKTYITFFITAVDGGGRENSTAVTIEIEDCNDHAPNIAIYKSTASIRENDRTPLVLTSVMVNDDDKGINSQFNCDLNDTTYFTMVKEDVYNQSNGRQLFMYNIKKIPDTFFDRESLSFYSVLIRCIDLGRPPLVGEKLFTVTIIDENDNAPKFGSDDIRFTLTENNNIGAPIGYVRAYDPDSNENGRVSYQILNNDENYYFTITILGKIEAKWKFDREIKDQYSLTIMAKDNGEPSLNDTCTVHIRILDVNDCVPVFKQQYFYQITEGNGLATIHAILGKVTADDKDLGENGTVYYA---IRQKYDHSNRQNNIGL-NLLKINLEGILNIYGVVDREQMVSIQAEIIAYDNGKPQLSAVANVIVDVLDVNDNKPKFKYPINKMNFINISTDSQVGKVLANFEAEDPDKGENGTITYSIISHKHMEQNLPYQLQNDGRLILTKYLREREGIR-LPDRLIIRASDNGIPPKAELVTVNIRYIPNNLTPRNNALPPGINKKSN--DKNRFSGGNVDNYRDSDST--------DNMTLLYILVGILFVVFIIVLLVLVYTYFSGRFS------------RSRQLDL-THEKELNNYCTDGTGNYECDLLNANAASCHEDFNKMAMGSISSPATDKNNYTHLMRMNEAKYTPI 924
BLAST of Protocadherin-11 X-linked vs. Planmine SMEST
Match: SMESG000007877.1 (SMESG000007877.1) HSP 1 Score: 526.939 bits (1356), Expect = 3.742e-169 Identity = 339/846 (40.07%), Postives = 503/846 (59.46%), Query Frame = 1
Query: 481 FQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIA--RCQGIDQENQVKTIGNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSG-----KLNLKNIRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNSNDN--FAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFPSNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRE-NFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYI-HSLTNLN---PTSIGKKSHSSDNNNFGFRLKNDNKNPISTKNFNPNLSDSMMVLYSLAAXXXXXXXXXXXXXXXXYWSKHYSVNDRYSKKIYKAGNVQLDLDTNLKEMKNVTKSIRSNRDCE------TSGNED-----ASAVCFIGDDGSSYTHLMMLSNSKYTPM 2943
F K ++IQEN IG+ LP A D DS + Y+I + I + NQ + ++F I + +I P L++IK IDREE F ILIA D G Q GSCT+TV + DVNDN+P+W N ++EC +G ++EL A DRDD +T NG + Y++SD + +++++++FYI G+ L L++ + + + I +ITA DG GR N T+V I IEDCNDH P I+I + EN + ++LT+V V D+DKG N F C LND+ K ++ N +Y I+ PDT FDRE +S Y+V I+C+D G P + + F++ IID NDNAP+F + F + ENN IG+ +G VRA D DS+ NG + Y ILN+++N F I+I G+I++K KFDRE D Y + A+DNGEP LND+ V ++I D+NDC PVF++ YF++ITE G + + L ++ A DKDLG+NGTV Y ++ N + L NL+K++ +G +++YG +DRE++ SIQ + A+D+G P LS +I++VLD+NDN P F +P N MNF+N+S + ++GK + + +D D+G NGTIT+S+I+ E N P+++Q +G +I+ ++E R LPDRLII+ASD G PK + T+ IRYI ++LT N P I KKS+ D N F ++ ++ ST D+M +LY L ILF +F+IVL VLV+ Y+S +S + QLDL T+ KE+ N N +C+ S +ED ++ D ++YTHLM ++ +KYTP+
Sbjct: 37 FSMRHKTLSIQENSDIGSELSLPTADDLDSEPNSIIRYFIKDIHSRDIRRMNQFQA----SRYFTIFIKTMNRMKI-PYLKLIKEIDREEIDRFELILIAEDSGKQQGSCTITVSIIDVNDNSPQWPTVNISKTVKECDRQGPLVELQAFDRDDSSTPNGQIKYKISDNSPKKELINRLFYIAGSSLFLSSQGLQLMDLKTYITFFITAVDGGGRENSTAVTIEIEDCNDHAPNIAIYKSTASIRENDRTPLVLTSVMVNDDDKGINSQFNCDLNDTTYFTMVKEDVYNQSNGRQLFMYNIKKIPDTFFDRESLSFYSVLIRCIDLGRPPLVGEKLFTVTIIDENDNAPKFGSDDIRFTLTENNNIGAPIGYVRAYDPDSNENGRVSYQILNNDENYYFTITILGKIEAKWKFDREIKDQYSLTIMAKDNGEPSLNDTCTVHIRILDVNDCVPVFKQQYFYQITEGNGLATIHAILGKVTADDKDLGENGTVYYA---IRQKYDHSNRQNNIGL-NLLKINLEGILNIYGVVDREQMVSIQAEIIAYDNGKPQLSAVANVIVDVLDVNDNKPKFKYPINKMNFINISTDSQVGKVLANFEAEDPDKGENGTITYSIISHKHMEQNLPYQLQNDGRLILTKYLREREGIR-LPDRLIIRASDNGIPPKAELVTVNIRYIPNNLTPRNNALPPGINKKSN--DKNRFSGGNVDNYRDSDST--------DNMTLLYILVGILFVVFIIVLLVLVYTYFSGRFS------------RSRQLDL-THEKELNNYCTDGTGNYECDLLNANAASCHEDFNKMAMGSISSPATDKNNYTHLMRMNEAKYTPI 849 HSP 2 Score: 71.633 bits (174), Expect = 3.220e-12 Identity = 76/256 (29.69%), Postives = 118/256 (46.09%), Query Frame = 1
Query: 1474 INIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSI--LNSND-----NFAISIYGEI------QSKIKF-------DREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQ--NGTVKYRLIDVKPIGIPGNSKLKAELRN-LIKVSFDGAISVYGNLDREEISS-IQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAP 2169
++I D NDN P+F + K + EN+ IGS + A DLDS N I Y I ++S D F S Y I + KI + DRE+ D +E ++ A D+G+ Q S + V I D+ND +P + I+++ E + L +++A D+D NG +KY++ D P K EL N L ++ L ++ + I + A D G +T + IE+ D ND+AP
Sbjct: 25 VDINDENDNIPQFSMRHKTLSIQENSDIGSELSLPTADDLDSEPNSIIRYFIKDIHSRDIRRMNQFQASRYFTIFIKTMNRMKIPYLKLIKEIDREEIDRFELILIAEDSGKQQ--GSCTITVSIIDVNDNSPQWPT---VNISKTVKECDRQGPLVELQAFDRDDSSTPNGQIKYKISDNSP---------KKELINRLFYIAGSSLFLSSQGLQLMDLKTYITFFITAVDGG--GRENSTAVTIEIEDCNDHAP 264
BLAST of Protocadherin-11 X-linked vs. Planmine SMEST
Match: SMESG000059440.1 (SMESG000059440.1) HSP 1 Score: 441.81 bits (1135), Expect = 1.052e-136 Identity = 297/800 (37.12%), Postives = 444/800 (55.50%), Query Frame = 1
Query: 154 FSIKLVITLNVEFSVDENCRIGHVVGNVYSKLNQLPNSS-----RSSLMKANEKDSY----FSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLD----QDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTI--GNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFD-----DNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS---NDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP-SNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRY 2481
FS+KL + SV+EN + +GN+ + S+ +S +++ + ++Y S+++ GD+ V S +DRE IC+ + C +L+ D ++ IEI DINDN P FQ +K I I EN+ + + LPVA+D+DS KYGVK YY+ EN + I GNN I P L +I ++DRE SF F L A+D G G C + V +TDVNDN P+W Y+ I EC +E +L+L A D+DDP T G + +++S+ +++ +++ +IFYI + L+L + N I + A DG GR NET++++ I+DCNDH PVI + + K+ EN+K KI++T + V DED+G N F CSLND+ ++L ++ I+++ + P FDREK S Y+VE+ C D G P MSS + +I I D NDN P F + K F + E+ IG +G V A D DSS N I YSI+ + F I+ G+I DRE D YEF V A+DNGEP LNDS +++ + D+ND P Y F+I ES+ K+ + ++ A+D+D+GQNGT ++R V+ P + I+V +G I +GN+DRE++ I +LV D+G P + TTT+ IEVLD+NDN P F +P N N++N++ + G + VK D D G+NG+I ++L N N ++ F IQ +G+II+ K+ PDRL+++A D G + TLYIRY
Sbjct: 19 FSVKLYL------SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISK-CLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVKKYYLKSISSSIYENYFELIDHGNN---------------INPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSF-KENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFR---VRSRSTPID----------IQVYNEGKIIYFGNIDREKVDKIDVLVDVIDNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDL-FSIQSDGQIILK---KKLDTKIKNPDRLVVEARDQGTPSLSATTTLYIRY 778
BLAST of Protocadherin-11 X-linked vs. Planmine SMEST
Match: SMESG000059440.1 (SMESG000059440.1) HSP 1 Score: 441.81 bits (1135), Expect = 2.079e-136 Identity = 297/800 (37.12%), Postives = 444/800 (55.50%), Query Frame = 1
Query: 154 FSIKLVITLNVEFSVDENCRIGHVVGNVYSKLNQLPNSS-----RSSLMKANEKDSY----FSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLD----QDTHAXXXXXXXXXXXXXXXXFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTI--GNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIATDFGNQTGSCXXXXXXXXXXXXAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKNIRFD-----DNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS---NDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISVYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP-SNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQPEGEIIIAHTMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRY 2481
FS+KL + SV+EN + +GN+ + S+ +S +++ + ++Y S+++ GD+ V S +DRE IC+ + C +L+ D ++ IEI DINDN P FQ +K I I EN+ + + LPVA+D+DS KYGVK YY+ EN + I GNN I P L +I ++DRE SF F L A+D G G C + V +TDVNDN P+W Y+ I EC +E +L+L A D+DDP T G + +++S+ +++ +++ +IFYI + L+L + N I + A DG GR NET++++ I+DCNDH PVI + + K+ EN+K KI++T + V DED+G N F CSLND+ ++L ++ I+++ + P FDREK S Y+VE+ C D G P MSS + +I I D NDN P F + K F + E+ IG +G V A D DSS N I YSI+ + F I+ G+I DRE D YEF V A+DNGEP LNDS +++ + D+ND P Y F+I ES+ K+ + ++ A+D+D+GQNGT ++R V+ P + I+V +G I +GN+DRE++ I +LV D+G P + TTT+ IEVLD+NDN P F +P N N++N++ + G + VK D D G+NG+I ++L N N ++ F IQ +G+II+ K+ PDRL+++A D G + TLYIRY
Sbjct: 16 FSVKLYL------SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISK-CLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVKKYYLKSISSSIYENYFELIDHGNN---------------INPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSF-KENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFR---VRSRSTPID----------IQVYNEGKIIYFGNIDREKVDKIDVLVDVIDNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDL-FSIQSDGQIILK---KKLDTKIKNPDRLVVEARDQGTPSLSATTTLYIRY 775 The following BLAST results are available for this feature:
BLAST of Protocadherin-11 X-linked vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin-11 X-linked vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin-11 X-linked vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30004358 ID=SMED30004358|Name=Protocadherin-11 X-linked|organism=Schmidtea mediterranea sexual|type=transcript|length=3447bpback to top protein sequence of SMED30004358-orf-1 >SMED30004358-orf-1 ID=SMED30004358-orf-1|Name=SMED30004358-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1066bp MLIELDILIIFSIKLVITLNVEFSVDENCRIGHVVGNVYSKLNQLPNSSRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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