Chromobox protein

Overview


Name	Chromobox protein
Smed ID	SMED30004311
Length (bp)	2623

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Chromobox protein (SMED30004311) t-SNE clustered cells

Violin plots show distribution of expression levels for Chromobox protein (SMED30004311) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Chromobox protein (SMED30004311) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Chromobox protein (SMED30004311) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30004311

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30004311	SMESG000019097.1	SmedASXL_025811	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30004311	SMESG000019097.1	SmedASXL_025811	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
nervous system	SMED30004311	SMESG000065471.1 SMESG000047257.1	dd_Smed_v4_8167_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30004311	SMESG000065471.1 SMESG000047257.1	dd_Smed_v4_8167_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Chromobox protein vs. Ensembl Human
Match: ASB15 (ankyrin repeat and SOCS box containing 15 [Source:HGNC Symbol;Acc:HGNC:19767])

HSP 1 Score: 58.9214 bits (141), Expect = 6.411e-9
Identity = 36/93 (38.71%), Postives = 51/93 (54.84%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTNFY 1745
            TPL LAV    V  VR LL  G  P+ T N   ETPL++A   G    V  L+ ++   D   +K  +A++ A + GR D+V++LLK G N +
Sbjct:  113 TPLTLAVKAGLVENVRTLLEKGVWPN-TKNDKGETPLLIAVKKGSYDMVSTLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVALLLKHGGNVH 204

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BLAST of Chromobox protein vs. Ensembl Human
Match: ANKRD50 (ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:HGNC:29223])

HSP 1 Score: 60.8474 bits (146), Expect = 1.067e-8
Identity = 44/116 (37.93%), Postives = 62/116 (53.45%), Query Frame = 3

Query: 1467 LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTD-YRIKSRTALYFAIENGRVDVVSMLLKFGTNF-YRIADNLSGSSLINDMFMGNRL 1808
            +TPL +A  +  V++V LLL  GA  D TDN +  TPL+ A+S+G+   V  LL + A  D    + RT L  A   G V+VV  LL  G +  +R  D+   + L    F G+RL
Sbjct:  570 MTPLLVAAYEGHVDVVDLLLEGGADVDHTDN-NGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHR--DDAGWTPLHMAAFEGHRL 682

HSP 2 Score: 54.6842 bits (130), Expect = 8.392e-7
Identity = 32/94 (34.04%), Postives = 54/94 (57.45%), Query Frame = 3

Query: 1461 ECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLKFGTN 1739
            E  + LQ A  +  V +V+LL+ +GA  D T N  A T L +A+  G+I  V+ LL++ A  ++  +  RTA+  A +NG   ++ +L K+G +
Sbjct:  832 EKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGA-TALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGAS 924

[Close]

BLAST of Chromobox protein vs. Ensembl Human
Match: ANKRD50 (ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:HGNC:29223])

HSP 1 Score: 60.8474 bits (146), Expect = 1.109e-8
Identity = 44/116 (37.93%), Postives = 62/116 (53.45%), Query Frame = 3

Query: 1467 LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTD-YRIKSRTALYFAIENGRVDVVSMLLKFGTNF-YRIADNLSGSSLINDMFMGNRL 1808
            +TPL +A  +  V++V LLL  GA  D TDN +  TPL+ A+S+G+   V  LL + A  D    + RT L  A   G V+VV  LL  G +  +R  D+   + L    F G+RL
Sbjct:  749 MTPLLVAAYEGHVDVVDLLLEGGADVDHTDN-NGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHR--DDAGWTPLHMAAFEGHRL 861

HSP 2 Score: 54.6842 bits (130), Expect = 8.756e-7
Identity = 31/91 (34.07%), Postives = 53/91 (58.24%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLKFGTN 1739
            + LQ A  +  V +V+LL+ +GA  D T N  A T L +A+  G+I  V+ LL++ A  ++  +  RTA+  A +NG   ++ +L K+G +
Sbjct: 1014 SALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGA-TALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGAS 1103

[Close]

BLAST of Chromobox protein vs. Ensembl Human
Match: ANK2 (ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493])

HSP 1 Score: 60.4622 bits (145), Expect = 1.499e-8
Identity = 35/95 (36.84%), Postives = 52/95 (54.74%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLK 1727
            +  T   LTP+ +A     +NIV LLL+ GA PD T N   ET L +A+  G +  V+ LL   A  D R +  +T L+ A   G+ ++V +LL+
Sbjct:  396 QAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT-NIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQ 489

HSP 2 Score: 56.9954 bits (136), Expect = 1.650e-7
Identity = 33/90 (36.67%), Postives = 52/90 (57.78%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDY-RIKSRTALYFAIENGRVDVVSMLLKFGT 1736
            TPL +A  KNR+ ++ LL++YGA       +   TP+ +A+ +G+++ V  LL   A  D   I+  TAL+ A   G+V+VV  LL+ G 
Sbjct:  371 TPLHIACKKNRIKVMELLVKYGASIQAITESGL-TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 459

HSP 3 Score: 52.7582 bits (125), Expect = 3.172e-6
Identity = 40/120 (33.33%), Postives = 59/120 (49.17%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYV 1826
            TPL +A     VN+  LLL  GA  DFT   +  TPL +AS  G  + VK LLD     D + +   T L+ A  +G   VV +LL+ G     +A   +G S ++    G+ +  V ++
Sbjct:  206 TPLHIAAHYGNVNVATLLLNRGAAVDFTAR-NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL--LARTKNGLSPLHMAAQGDHVECVKHL 322

HSP 4 Score: 51.9878 bits (123), Expect = 6.741e-6
Identity = 34/91 (37.36%), Postives = 46/91 (50.55%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTN 1739
            TPL +A  KN++ I   LL YGA  +        TPL LAS  G+   V  LLD  A      KS  T+L+ A +  +V+V  +L K G +
Sbjct:  569 TPLHIAAKKNQMQIASTLLNYGAETNIVTKQGV-TPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGAD 658

[Close]

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLK 1727
            +  T   LTP+ +A     +NIV LLL+ GA PD T N   ET L +A+  G +  V+ LL   A  D R +  +T L+ A   G+ ++V +LL+
Sbjct:  396 QAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT-NIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQ 489

HSP 2 Score: 56.9954 bits (136), Expect = 1.650e-7
Identity = 33/90 (36.67%), Postives = 52/90 (57.78%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDY-RIKSRTALYFAIENGRVDVVSMLLKFGT 1736
            TPL +A  KNR+ ++ LL++YGA       +   TP+ +A+ +G+++ V  LL   A  D   I+  TAL+ A   G+V+VV  LL+ G 
Sbjct:  371 TPLHIACKKNRIKVMELLVKYGASIQAITESGL-TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 459

HSP 3 Score: 52.7582 bits (125), Expect = 3.172e-6
Identity = 40/120 (33.33%), Postives = 59/120 (49.17%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYV 1826
            TPL +A     VN+  LLL  GA  DFT   +  TPL +AS  G  + VK LLD     D + +   T L+ A  +G   VV +LL+ G     +A   +G S ++    G+ +  V ++
Sbjct:  206 TPLHIAAHYGNVNVATLLLNRGAAVDFTAR-NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL--LARTKNGLSPLHMAAQGDHVECVKHL 322

HSP 4 Score: 51.9878 bits (123), Expect = 6.741e-6
Identity = 34/91 (37.36%), Postives = 46/91 (50.55%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTN 1739
            TPL +A  KN++ I   LL YGA  +        TPL LAS  G+   V  LLD  A      KS  T+L+ A +  +V+V  +L K G +
Sbjct:  569 TPLHIAAKKNQMQIASTLLNYGAETNIVTKQGV-TPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGAD 658

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BLAST of Chromobox protein vs. Ensembl Celegans
Match: trp-4 (TRP (Transient receptor potential) channel family [Source:UniProtKB/TrEMBL;Acc:Q9GRV5])

HSP 1 Score: 56.6102 bits (135), Expect = 8.328e-8
Identity = 39/104 (37.50%), Postives = 55/104 (52.88%), Query Frame = 3

Query: 1443 NEKFTPEC-LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSA----FTDYRIKSRTALYFAIENGRVDVVSMLLKFGTN 1739
            N++F+ E   TPL LA      ++VR+LL  G   D T  T    PL LA+  G+I  V  LL  S       D+R   RT L+ A +NG  ++VS+L+  G+N
Sbjct: 1197 NKEFSTEYGFTPLHLAAQSGHDSLVRMLLNQGVQVDATSTTMNVIPLHLAAQQGHIAVVGMLLSRSTQQQHAKDWR--GRTPLHLAAQNGHYEMVSLLIAQGSN 1298

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BLAST of Chromobox protein vs. Ensembl Celegans
Match: hpl-2 (Chromo-domain protein; HP1 Like (Heterochromatin protein) [Source:UniProtKB/TrEMBL;Acc:G5EFS9])

HSP 1 Score: 51.2174 bits (121), Expect = 3.826e-7
Identity = 23/57 (40.35%), Postives = 39/57 (68.42%), Query Frame = 3

Query:  360 DNFYIVEKIVGHKMCN-GKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDFKNKIS 527
            DN ++VEK++  +    G+  F +QWQG+ ES+ SWEP ENL  V +++++F+ + S
Sbjct:   16 DNVFMVEKVLDKRTGKAGRDEFLIQWQGFPESDSSWEPRENLQCV-EMLDEFEREFS 71

[Close]

BLAST of Chromobox protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 54.6842 bits (130), Expect = 3.835e-7
Identity = 40/124 (32.26%), Postives = 61/124 (49.19%), Query Frame = 3

Query: 1467 LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLL 1835
             TPL +A  KNR+ +V LLL+Y A  + T  +   TPL +A+ +G I+ V  LL   A  D   ++  T L+ A    + DVV +L++ G        +     L   + + +RL N   V LL
Sbjct:  393 FTPLHIACKKNRIKVVELLLKYRAAIEATTES-GLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKV-----DAQARELQTPLHIASRLGNTDIVILL 510

HSP 2 Score: 53.5286 bits (127), Expect = 8.795e-7
Identity = 36/99 (36.36%), Postives = 50/99 (50.51%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKS-RTALYFAIENGRVDVVSMLLKFGTN 1739
            E  T   LTPL +A     +NIV  LL+ GA PD  +    ETPL LA+       V+ L+   A  D + +  +T L+ A   G  D+V +LL+ G N
Sbjct:  419 EATTESGLTPLHVAAFMGAINIVIYLLQQGANPD-VETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN 516

HSP 3 Score: 52.7582 bits (125), Expect = 1.462e-6
Identity = 34/93 (36.56%), Postives = 49/93 (52.69%), Query Frame = 3

Query: 1455 TPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKF 1730
            T   L PL +A   + V+  R LL + AP D     D  TPL +A+  G++   K LLD SA  + R +   T L+ A +  R+ VV +LLK+
Sbjct:  323 TKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDV-TVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKY 414

[Close]

Query: 1467 LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLL 1835
             TPL +A  KNR+ +V LLL+Y A  + T  +   TPL +A+ +G I+ V  LL   A  D   ++  T L+ A    + DVV +L++ G        +     L   + + +RL N   V LL
Sbjct:  393 FTPLHIACKKNRIKVVELLLKYRAAIEATTES-GLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKV-----DAQARELQTPLHIASRLGNTDIVILL 510

HSP 2 Score: 53.5286 bits (127), Expect = 8.795e-7
Identity = 36/99 (36.36%), Postives = 50/99 (50.51%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKS-RTALYFAIENGRVDVVSMLLKFGTN 1739
            E  T   LTPL +A     +NIV  LL+ GA PD  +    ETPL LA+       V+ L+   A  D + +  +T L+ A   G  D+V +LL+ G N
Sbjct:  419 EATTESGLTPLHVAAFMGAINIVIYLLQQGANPD-VETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN 516

HSP 3 Score: 52.7582 bits (125), Expect = 1.462e-6
Identity = 34/93 (36.56%), Postives = 49/93 (52.69%), Query Frame = 3

Query: 1455 TPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKF 1730
            T   L PL +A   + V+  R LL + AP D     D  TPL +A+  G++   K LLD SA  + R +   T L+ A +  R+ VV +LLK+
Sbjct:  323 TKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDV-TVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKY 414

[Close]

BLAST of Chromobox protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 54.6842 bits (130), Expect = 3.908e-7
Identity = 40/124 (32.26%), Postives = 61/124 (49.19%), Query Frame = 3

Query: 1467 LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLL 1835
             TPL +A  KNR+ +V LLL+Y A  + T  +   TPL +A+ +G I+ V  LL   A  D   ++  T L+ A    + DVV +L++ G        +     L   + + +RL N   V LL
Sbjct:  393 FTPLHIACKKNRIKVVELLLKYRAAIEATTES-GLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKV-----DAQARELQTPLHIASRLGNTDIVILL 510

HSP 2 Score: 53.5286 bits (127), Expect = 9.037e-7
Identity = 36/99 (36.36%), Postives = 50/99 (50.51%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKS-RTALYFAIENGRVDVVSMLLKFGTN 1739
            E  T   LTPL +A     +NIV  LL+ GA PD  +    ETPL LA+       V+ L+   A  D + +  +T L+ A   G  D+V +LL+ G N
Sbjct:  419 EATTESGLTPLHVAAFMGAINIVIYLLQQGANPD-VETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN 516

HSP 3 Score: 52.7582 bits (125), Expect = 1.477e-6
Identity = 34/93 (36.56%), Postives = 49/93 (52.69%), Query Frame = 3

Query: 1455 TPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKF 1730
            T   L PL +A   + V+  R LL + AP D     D  TPL +A+  G++   K LLD SA  + R +   T L+ A +  R+ VV +LLK+
Sbjct:  323 TKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDV-TVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKY 414

[Close]

BLAST of Chromobox protein vs. Ensembl Fly
Match: rhi (gene:FBgn0004400 transcript:FBtr0086897)

HSP 1 Score: 57.3806 bits (137), Expect = 3.836e-8
Identity = 20/52 (38.46%), Postives = 35/52 (67.31%), Query Frame = 3

Query:  369 YIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDFKNKI 524
            Y+VEKI+G +  NG+    V+W G+    ++WEP EN+ N + L+ DF++++
Sbjct:   24 YVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESEV 75

[Close]

BLAST of Chromobox protein vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0344224)

HSP 1 Score: 56.9954 bits (136), Expect = 9.100e-8
Identity = 39/124 (31.45%), Postives = 64/124 (51.61%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAE-TPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLL 1835
            TPL +A  KNR+ +V LLLR+GA    +  T++  TPL +A+ +G ++ V  LL + A  D   ++  T L+ A    + D++ +LL+ G        +         + + +RL NV  V LL
Sbjct:  372 TPLHIACKKNRLKVVELLLRHGA--SISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQV-----DARAREQQTPLHIASRLGNVDIVMLL 488

[Close]

BLAST of Chromobox protein vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303125)

HSP 1 Score: 56.9954 bits (136), Expect = 1.001e-7
Identity = 39/124 (31.45%), Postives = 64/124 (51.61%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAE-TPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLL 1835
            TPL +A  KNR+ +V LLLR+GA    +  T++  TPL +A+ +G ++ V  LL + A  D   ++  T L+ A    + D++ +LL+ G        +         + + +RL NV  V LL
Sbjct:  372 TPLHIACKKNRLKVVELLLRHGA--SISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQV-----DARAREQQTPLHIASRLGNVDIVMLL 488

[Close]

BLAST of Chromobox protein vs. Ensembl Fly
Match: CG3104 (gene:FBgn0031473 transcript:FBtr0335132)

HSP 1 Score: 55.0694 bits (131), Expect = 1.262e-7
Identity = 30/92 (32.61%), Postives = 52/92 (56.52%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTNF 1742
            TPL  A     +++V++L++ GA  D T + D  TPL +A   G++  V+ LLD  A  +  +K R T ++ + +NG   V+S+L++ G   
Sbjct:   78 TPLFFAAQGGHLDVVKILIKAGASVD-TPSADGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDRATPVFISAQNGHRTVLSLLIQAGAEI 168

HSP 2 Score: 50.8322 bits (120), Expect = 2.619e-6
Identity = 34/100 (34.00%), Postives = 53/100 (53.00%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTD-YRIKSRTALYFAIENGRVDVVSMLLKFGTNF 1742
            +K TP  +     A+  + V ++R+L       D  D  D  TPLILA++ G+ + V  LLD  A  +  R+   T L+FA + G +DVV +L+K G + 
Sbjct:    4 KKETPSDVQLHMAAMRGDEVALLRVLDSGKVHVDCKDE-DGTTPLILAAAGGHTYCVMELLDQGADPNSRRLTGTTPLFFAAQGGHLDVVKILIKAGASV 102

[Close]

BLAST of Chromobox protein vs. Ensembl Fly
Match: CG3104 (gene:FBgn0031473 transcript:FBtr0077686)

HSP 1 Score: 55.0694 bits (131), Expect = 1.262e-7
Identity = 30/92 (32.61%), Postives = 52/92 (56.52%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTNF 1742
            TPL  A     +++V++L++ GA  D T + D  TPL +A   G++  V+ LLD  A  +  +K R T ++ + +NG   V+S+L++ G   
Sbjct:   78 TPLFFAAQGGHLDVVKILIKAGASVD-TPSADGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDRATPVFISAQNGHRTVLSLLIQAGAEI 168

HSP 2 Score: 50.8322 bits (120), Expect = 2.619e-6
Identity = 34/100 (34.00%), Postives = 53/100 (53.00%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTD-YRIKSRTALYFAIENGRVDVVSMLLKFGTNF 1742
            +K TP  +     A+  + V ++R+L       D  D  D  TPLILA++ G+ + V  LLD  A  +  R+   T L+FA + G +DVV +L+K G + 
Sbjct:    4 KKETPSDVQLHMAAMRGDEVALLRVLDSGKVHVDCKDE-DGTTPLILAAAGGHTYCVMELLDQGADPNSRRLTGTTPLFFAAQGGHLDVVKILIKAGASV 102

[Close]

BLAST of Chromobox protein vs. Ensembl Zebrafish
Match: ANKRD50 (ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:HGNC:29223])

HSP 1 Score: 64.6994 bits (156), Expect = 5.206e-10
Identity = 38/92 (41.30%), Postives = 52/92 (56.52%), Query Frame = 3

Query: 1461 ECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTD-YRIKSRTALYFAIENGRVDVVSMLLKFG 1733
            +C+TPL +A  +  V++V LLL  GA  D TDN +  TPL+ A+S+G+   V  LL + A  D    + RT L  A   G V+VV  LL  G
Sbjct:  457 DCMTPLLVAAYEGHVDVVDLLLEGGADVDHTDN-NGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRG 547

[Close]

BLAST of Chromobox protein vs. Ensembl Zebrafish
Match: kidins220b (kinase D-interacting substrate 220b [Source:NCBI gene;Acc:335881])

HSP 1 Score: 60.8474 bits (146), Expect = 8.757e-9
Identity = 36/91 (39.56%), Postives = 56/91 (61.54%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTN 1739
            TPL LA  +  + IV+ L+R GA  +  D+ D  + LI A+  G++  VK LL+ SA+ ++R +   TAL +A   GRV+V ++LL+ G N
Sbjct:   48 TPLMLASEQGSLEIVQELIRRGANVNL-DDVDCWSALISAAKEGHVEVVKELLENSAYIEHRDMGGWTALTWASYKGRVEVATVLLENGAN 137

[Close]

BLAST of Chromobox protein vs. Ensembl Zebrafish
Match: ankk1 (ankyrin repeat and kinase domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071015-4])

HSP 1 Score: 60.077 bits (144), Expect = 9.177e-9
Identity = 50/143 (34.97%), Postives = 70/143 (48.95%), Query Frame = 3

Query: 1389 DKYHLLHNALQNG------------VRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSL 1778
            D++  LH A+Q G             R D  EK   +  TPL LA      NIVR+LLR     D  ++    T L +AS  G+I+ VK LL+  A  D +  ++ TAL+ A E G   VV +L+  G +  ++ D  S SSL
Sbjct:  413 DQWTALHFAVQAGDDRATRFLLDNKARADAKEK---DGWTPLHLAAQNGHENIVRILLRRLDSVDVQEHQSCRTALHVASIYGHINIVKLLLNKGADIDKQDNNQSTALHLAAEEGHFRVVRLLVNSGADVNKV-DEQSYSSL 551

[Close]

BLAST of Chromobox protein vs. Ensembl Zebrafish
Match: asb2b (ankyrin repeat and SOCS box containing 2b [Source:ZFIN;Acc:ZDB-GENE-040426-20])

HSP 1 Score: 59.6918 bits (143), Expect = 1.127e-8
Identity = 45/137 (32.85%), Postives = 67/137 (48.91%), Query Frame = 3

Query: 1335 SDLISIDNFEDLKCSILMDKYHLLHNALQNG-VRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTN 1739
            ++++  D++  L  +    + H L   L+ G V  D   K T +  T L LAV   ++  VR+LL  GA PD   N   ETPL  A     +  V+ LL   A  D R ++ R+AL+ A E G V +   LL+ G +
Sbjct:   49 TEVLDGDDWTPLHEAAYRGQNHCLQALLREGQVCVD---KRTLQEETALMLAVQARQLECVRILLEAGADPDIC-NKSKETPLYRACEQECVQMVEVLLQRGAVVDQRCVRGRSALHAAAERGCVQICVCLLRAGAS 181

[Close]

BLAST of Chromobox protein vs. Ensembl Zebrafish
Match: asb2b (ankyrin repeat and SOCS box containing 2b [Source:ZFIN;Acc:ZDB-GENE-040426-20])

HSP 1 Score: 58.9214 bits (141), Expect = 1.969e-8
Identity = 45/138 (32.61%), Postives = 67/138 (48.55%), Query Frame = 3

Query: 1332 DSDLISIDNFEDLKCSILMDKYHLLHNALQNG-VRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTN 1739
             ++++  D++  L  +    + H L   L+ G V  D   K T +  T L LAV   ++  VR+LL  GA PD   N   ETPL  A     +  V+ LL   A  D R ++ R+AL+ A E G V +   LL+ G +
Sbjct:   48 GTEVLDGDDWTPLHEAAYRGQNHCLQALLREGQVCVD---KRTLQEETALMLAVQARQLECVRILLEAGADPDIC-NKSKETPLYRACEQECVQMVEVLLQRGAVVDQRCVRGRSALHAAAERGCVQICVCLLRAGAS 181

[Close]

BLAST of Chromobox protein vs. Ensembl Xenopus
Match: gart (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:Xenbase;Acc:XB-GENE-993017])

HSP 1 Score: 62.003 bits (149), Expect = 4.789e-9
Identity = 46/132 (34.85%), Postives = 67/132 (50.76%), Query Frame = 3

Query: 1416 LQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTD-YRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRL 1808
            ++ G   D  +K   + +TPL +A  +  V++V LLL  GA  D TDN +  TPL+ A+S+G+   V  LL + A  D    + RT L  A   G V+VV  LL  G +     D+   + L    F G+RL
Sbjct:  723 IEQGAEVDHCDK---DGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDN-NGRTPLLAAASMGHAAVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENH-RDDAGWTPLHMAAFEGHRL 849

[Close]

BLAST of Chromobox protein vs. Ensembl Xenopus
Match: ANK2 (ankyrin 2, neuronal [Source:NCBI gene;Acc:100494806])

HSP 1 Score: 60.8474 bits (146), Expect = 1.074e-8
Identity = 35/95 (36.84%), Postives = 52/95 (54.74%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLK 1727
            +  T   LTP+ +A     +NIV LLL+ GA PD T N   ET L +A+  G +  V+ LL   A  D R +  +T L+ A   G+ ++V +LL+
Sbjct:  404 QAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT-NIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQ 497

HSP 2 Score: 57.7658 bits (138), Expect = 9.278e-8
Identity = 33/89 (37.08%), Postives = 52/89 (58.43%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDY-RIKSRTALYFAIENGRVDVVSMLLKFG 1733
            TPL +A  KNR+ ++ LL++YGA       +   TP+ +A+ +G+++ V  LL   A  D   I+  TAL+ A   G+V+VV  LL+ G
Sbjct:  379 TPLHIACKKNRIKVMELLVKYGASIQAITESGL-TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 466

HSP 3 Score: 55.0694 bits (131), Expect = 6.995e-7
Identity = 46/143 (32.17%), Postives = 65/143 (45.45%), Query Frame = 3

Query: 1416 LQNGVRFDWNEKF-----TPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYV 1826
            LQN    D   K      T    TPL +A     VN+  LLL  GA  DFT   +  TPL +AS  G  + VK LLD     D + +   T L+ A  +G   VV +LL+ G     +A   +G S ++    G+ +  V ++
Sbjct:  191 LQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTAR-NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL--LARTKNGLSPLHMAAQGDHVECVKHL 330

[Close]

BLAST of Chromobox protein vs. Ensembl Xenopus
Match: ANK2 (ankyrin 2, neuronal [Source:NCBI gene;Acc:100494806])

HSP 1 Score: 60.8474 bits (146), Expect = 1.106e-8
Identity = 35/95 (36.84%), Postives = 52/95 (54.74%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLK 1727
            +  T   LTP+ +A     +NIV LLL+ GA PD T N   ET L +A+  G +  V+ LL   A  D R +  +T L+ A   G+ ++V +LL+
Sbjct:  404 QAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT-NIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQ 497

HSP 2 Score: 58.151 bits (139), Expect = 8.922e-8
Identity = 33/89 (37.08%), Postives = 52/89 (58.43%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDY-RIKSRTALYFAIENGRVDVVSMLLKFG 1733
            TPL +A  KNR+ ++ LL++YGA       +   TP+ +A+ +G+++ V  LL   A  D   I+  TAL+ A   G+V+VV  LL+ G
Sbjct:  379 TPLHIACKKNRIKVMELLVKYGASIQAITESGL-TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 466

HSP 3 Score: 55.0694 bits (131), Expect = 6.609e-7
Identity = 46/143 (32.17%), Postives = 65/143 (45.45%), Query Frame = 3

Query: 1416 LQNGVRFDWNEKF-----TPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYV 1826
            LQN    D   K      T    TPL +A     VN+  LLL  GA  DFT   +  TPL +AS  G  + VK LLD     D + +   T L+ A  +G   VV +LL+ G     +A   +G S ++    G+ +  V ++
Sbjct:  191 LQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTAR-NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL--LARTKNGLSPLHMAAQGDHVECVKHL 330

[Close]

BLAST of Chromobox protein vs. Ensembl Xenopus
Match: ANK2 (ankyrin 2, neuronal [Source:NCBI gene;Acc:100494806])

HSP 1 Score: 60.8474 bits (146), Expect = 1.116e-8
Identity = 35/95 (36.84%), Postives = 52/95 (54.74%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLK 1727
            +  T   LTP+ +A     +NIV LLL+ GA PD T N   ET L +A+  G +  V+ LL   A  D R +  +T L+ A   G+ ++V +LL+
Sbjct:  441 QAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT-NIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQ 534

HSP 2 Score: 58.151 bits (139), Expect = 8.851e-8
Identity = 33/89 (37.08%), Postives = 52/89 (58.43%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDY-RIKSRTALYFAIENGRVDVVSMLLKFG 1733
            TPL +A  KNR+ ++ LL++YGA       +   TP+ +A+ +G+++ V  LL   A  D   I+  TAL+ A   G+V+VV  LL+ G
Sbjct:  416 TPLHIACKKNRIKVMELLVKYGASIQAITESGL-TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 503

HSP 3 Score: 55.0694 bits (131), Expect = 6.725e-7
Identity = 46/143 (32.17%), Postives = 65/143 (45.45%), Query Frame = 3

Query: 1416 LQNGVRFDWNEKF-----TPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYV 1826
            LQN    D   K      T    TPL +A     VN+  LLL  GA  DFT   +  TPL +AS  G  + VK LLD     D + +   T L+ A  +G   VV +LL+ G     +A   +G S ++    G+ +  V ++
Sbjct:  228 LQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTAR-NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL--LARTKNGLSPLHMAAQGDHVECVKHL 367

[Close]

BLAST of Chromobox protein vs. Ensembl Xenopus
Match: ANK2 (ankyrin 2, neuronal [Source:NCBI gene;Acc:100494806])

HSP 1 Score: 60.8474 bits (146), Expect = 1.145e-8
Identity = 35/95 (36.84%), Postives = 52/95 (54.74%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLK 1727
            +  T   LTP+ +A     +NIV LLL+ GA PD T N   ET L +A+  G +  V+ LL   A  D R +  +T L+ A   G+ ++V +LL+
Sbjct:  425 QAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT-NIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQ 518

HSP 2 Score: 58.151 bits (139), Expect = 8.925e-8
Identity = 33/89 (37.08%), Postives = 52/89 (58.43%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDY-RIKSRTALYFAIENGRVDVVSMLLKFG 1733
            TPL +A  KNR+ ++ LL++YGA       +   TP+ +A+ +G+++ V  LL   A  D   I+  TAL+ A   G+V+VV  LL+ G
Sbjct:  400 TPLHIACKKNRIKVMELLVKYGASIQAITESGL-TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 487

HSP 3 Score: 55.0694 bits (131), Expect = 6.611e-7
Identity = 46/143 (32.17%), Postives = 65/143 (45.45%), Query Frame = 3

Query: 1416 LQNGVRFDWNEKF-----TPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYV 1826
            LQN    D   K      T    TPL +A     VN+  LLL  GA  DFT   +  TPL +AS  G  + VK LLD     D + +   T L+ A  +G   VV +LL+ G     +A   +G S ++    G+ +  V ++
Sbjct:  212 LQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTAR-NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL--LARTKNGLSPLHMAAQGDHVECVKHL 351

[Close]

BLAST of Chromobox protein vs. Ensembl Mouse
Match: Ankrd50 (ankyrin repeat domain 50 [Source:MGI Symbol;Acc:MGI:2139777])

HSP 1 Score: 60.8474 bits (146), Expect = 7.252e-9
Identity = 43/115 (37.39%), Postives = 60/115 (52.17%), Query Frame = 3

Query: 1467 LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTD-YRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRL 1808
            +TPL +A  +  V++V LLL  GA  D TDN +  TPL+ A+S+G+   V  LL + A  D    + RT L  A   G V+VV  LL  G +     D+   + L    F G+RL
Sbjct:  712 MTPLLVAAYEGHVDVVDLLLEGGADVDHTDN-NGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDESH-RDDAGWTPLHMAAFEGHRL 824

HSP 2 Score: 53.9138 bits (128), Expect = 1.083e-6
Identity = 31/94 (32.98%), Postives = 54/94 (57.45%), Query Frame = 3

Query: 1461 ECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLKFGTN 1739
            E  + LQ A  +  V +V+LL+ +GA  D T N  A T L +A+  G++  V+ LL++ A  ++  +  RTA+  A +NG   ++ +L K+G +
Sbjct:  974 EKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGA-TALCIAAQEGHVDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGAS 1066

[Close]

BLAST of Chromobox protein vs. Ensembl Mouse
Match: Kidins220 (kinase D-interacting substrate 220 [Source:MGI Symbol;Acc:MGI:1924730])

HSP 1 Score: 60.4622 bits (145), Expect = 1.100e-8
Identity = 40/95 (42.11%), Postives = 53/95 (55.79%), Query Frame = 3

Query: 1461 EC-LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTN 1739
            EC  TPL +A  +  V IV+ L++ GA  +  D  D  T LI AS  G+IH V+ LL   A  ++R +   TAL +A   GR DVV +LL  G N
Sbjct:   36 ECGQTPLMIAAEQGNVEIVKELIKNGANCNLED-LDNWTALISASKEGHIHIVEELLKCGANLEHRDMGGWTALMWACYKGRTDVVELLLSHGAN 129

[Close]

BLAST of Chromobox protein vs. Ensembl Mouse
Match: Kidins220 (kinase D-interacting substrate 220 [Source:MGI Symbol;Acc:MGI:1924730])

HSP 1 Score: 60.4622 bits (145), Expect = 1.141e-8
Identity = 40/95 (42.11%), Postives = 53/95 (55.79%), Query Frame = 3

Query: 1461 EC-LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTN 1739
            EC  TPL +A  +  V IV+ L++ GA  +  D  D  T LI AS  G+IH V+ LL   A  ++R +   TAL +A   GR DVV +LL  G N
Sbjct:   36 ECGQTPLMIAAEQGNVEIVKELIKNGANCNLED-LDNWTALISASKEGHIHIVEELLKCGANLEHRDMGGWTALMWACYKGRTDVVELLLSHGAN 129

[Close]

BLAST of Chromobox protein vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 60.077 bits (144), Expect = 1.368e-8
Identity = 35/95 (36.84%), Postives = 52/95 (54.74%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLK 1727
            +  T   LTP+ +A     +NIV LLL+ GA PD T N   ET L +A+  G +  V+ LL   A  D R +  +T L+ A   G+ ++V +LL+
Sbjct:  404 QAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT-NIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQ 497

HSP 2 Score: 55.8398 bits (133), Expect = 2.681e-7
Identity = 33/90 (36.67%), Postives = 52/90 (57.78%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDY-RIKSRTALYFAIENGRVDVVSMLLKFGT 1736
            TPL +A  KNR+ ++ LL++YGA       +   TP+ +A+ +G+++ V  LL   A  D   I+  TAL+ A   G+V+VV  LL+ G 
Sbjct:  379 TPLHIACKKNRIKVMELLVKYGASIQAITESGL-TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 467

[Close]

BLAST of Chromobox protein vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 59.6918 bits (143), Expect = 1.732e-8
Identity = 35/95 (36.84%), Postives = 52/95 (54.74%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLK 1727
            +  T   LTP+ +A     +NIV LLL+ GA PD T N   ET L +A+  G +  V+ LL   A  D R +  +T L+ A   G+ ++V +LL+
Sbjct:  421 QAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT-NIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQ 514

HSP 2 Score: 55.8398 bits (133), Expect = 2.881e-7
Identity = 33/90 (36.67%), Postives = 52/90 (57.78%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDY-RIKSRTALYFAIENGRVDVVSMLLKFGT 1736
            TPL +A  KNR+ ++ LL++YGA       +   TP+ +A+ +G+++ V  LL   A  D   I+  TAL+ A   G+V+VV  LL+ G 
Sbjct:  396 TPLHIACKKNRIKVMELLVKYGASIQAITESGL-TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 484

[Close]

BLAST of Chromobox protein vs. UniProt/SwissProt
Match: sp|Q9EQG6|KDIS_RAT (Kinase D-interacting substrate of 220 kDa OS=Rattus norvegicus OX=10116 GN=Kidins220 PE=1 SV=2)

HSP 1 Score: 63.1586 bits (152), Expect = 1.233e-8
Identity = 42/95 (44.21%), Postives = 53/95 (55.79%), Query Frame = 3

Query: 1461 EC-LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTN 1739
            EC  TPL LA  +  V IV+ LL+ GA  +  D  D  T LI AS  G+IH V+ LL   A  ++R +   TAL +A   GR DVV +LL  G N
Sbjct:   36 ECGQTPLMLAAEQGNVEIVKELLKNGANCNLED-LDNWTALISASKEGHIHIVEELLKSGASLEHRDMGGWTALMWACYKGRTDVVELLLSHGAN 129

[Close]

BLAST of Chromobox protein vs. UniProt/SwissProt
Match: sp|Q9ULJ7|ANR50_HUMAN (Ankyrin repeat domain-containing protein 50 OS=Homo sapiens OX=9606 GN=ANKRD50 PE=1 SV=4)

HSP 1 Score: 60.8474 bits (146), Expect = 5.323e-8
Identity = 44/116 (37.93%), Postives = 62/116 (53.45%), Query Frame = 3

Query: 1467 LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTD-YRIKSRTALYFAIENGRVDVVSMLLKFGTNF-YRIADNLSGSSLINDMFMGNRL 1808
            +TPL +A  +  V++V LLL  GA  D TDN +  TPL+ A+S+G+   V  LL + A  D    + RT L  A   G V+VV  LL  G +  +R  D+   + L    F G+RL
Sbjct:  749 MTPLLVAAYEGHVDVVDLLLEGGADVDHTDN-NGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHR--DDAGWTPLHMAAFEGHRL 861

HSP 2 Score: 54.6842 bits (130), Expect = 4.205e-6
Identity = 31/91 (34.07%), Postives = 53/91 (58.24%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLKFGTN 1739
            + LQ A  +  V +V+LL+ +GA  D T N  A T L +A+  G+I  V+ LL++ A  ++  +  RTA+  A +NG   ++ +L K+G +
Sbjct: 1014 SALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGA-TALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGAS 1103

[Close]

BLAST of Chromobox protein vs. UniProt/SwissProt
Match: sp|Q7T163|KDISB_DANRE (Kinase D-interacting substrate of 220 kDa B OS=Danio rerio OX=7955 GN=kidins220b PE=1 SV=3)

HSP 1 Score: 60.4622 bits (145), Expect = 6.667e-8
Identity = 36/91 (39.56%), Postives = 56/91 (61.54%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTN 1739
            TPL LA  +  + IV+ L+R GA  +  D+ D  + LI A+  G++  VK LL+ SA+ ++R +   TAL +A   GRV+V ++LL+ G N
Sbjct:   48 TPLMLASEQGSLEIVQELIRRGANVNL-DDVDCWSALISAAKEGHVEVVKELLENSAYIEHRDMGGWTALTWASYKGRVEVATVLLENGAN 137

[Close]

BLAST of Chromobox protein vs. UniProt/SwissProt
Match: sp|Q96NW4|ANR27_HUMAN (Ankyrin repeat domain-containing protein 27 OS=Homo sapiens OX=9606 GN=ANKRD27 PE=1 SV=2)

HSP 1 Score: 59.3066 bits (142), Expect = 1.369e-7
Identity = 41/140 (29.29%), Postives = 69/140 (49.29%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLLALLRTYHMSFINSLNRT 1886
            +PL +A    R +++ LLL++GA      N D   PL LA   G+   VK LLD +A  + + +   T L +A   G  ++V++LL+ G +    A N  G++ +++      +   V+V  L LL    +  +N   RT
Sbjct:  746 SPLHVAALHGRADLIPLLLKHGANAG-ARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASIN--ASNNKGNTALHEAV----IEKHVFVVELLLLHGASVQVLNKRQRT 878

[Close]

BLAST of Chromobox protein vs. UniProt/SwissProt
Match: sp|Q8NFD2|ANKK1_HUMAN (Ankyrin repeat and protein kinase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKK1 PE=1 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 1.592e-7
Identity = 38/108 (35.19%), Postives = 57/108 (52.78%), Query Frame = 3

Query: 1416 LQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKS-RTALYFAIENGRVDVVSMLLKFGT 1736
            L +G   D  E+   E  TPL LA   N  N+ RLL+   A P+  +  + +TPL +A+  G++  VK L    A  D + ++ RT L+ A+E G+V  +  LLK G 
Sbjct:  448 LDHGACVDAQER---EGWTPLHLAAQNNFENVARLLVSRQADPNLHE-AEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGA 551

[Close]

BLAST of Chromobox protein vs. TrEMBL
Match: G4V7S3 (Chromobox protein-related (Chromobox 1) (Heterochromatin 1) OS=Schistosoma mansoni OX=6183 GN=Smp_144550 PE=4 SV=1)

HSP 1 Score: 123.635 bits (309), Expect = 5.548e-25
Identity = 72/177 (40.68%), Postives = 96/177 (54.24%), Query Frame = 3

Query:  348 DSRTDNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDF----KNKI------------------------------------------SDDKFEEXXXXXXXXXXXXXXGCYEYVPSNKVVATKTKYFDDIRDGKIDLTKNDLYSRVKTRKRLHLEEGSD 740
            D+ + N YIVE I+  ++  G+ Y+KV+W+G+    DSWEPE+NLTNVLD+I +F    K+KI                                          S+++    S    +  +SR  G YEYVP +++VA+KTKYFDDIRDGKIDL  NDLYSRVKTRKR   E  S+
Sbjct:   43 DTNSVNVYIVESILNERIIKGQKYYKVRWEGFPPEADSWEPEKNLTNVLDIISEFHNGSKSKISKNLDIHKDCQTVFENSPASVPTPPATPCSVLQNSHNSLRGSSEERQLNKSVKRKHFTKSRTGGRYEYVPKHQLVASKTKYFDDIRDGKIDLCSNDLYSRVKTRKRCAAESASN 219

HSP 2 Score: 62.7734 bits (151), Expect = 3.845e-6
Identity = 51/177 (28.81%), Postives = 92/177 (51.98%), Query Frame = 3

Query: 1797 GNRLSNVVYVDLL-ALLRTYHMSFINSLNRTITRYFTKHFIKQICIIFPHQWVSVLEKEFHIDF-----LLDSSIM-TNIDTPILLLVHG-IQADCDFDFWLDNNCCCV-ESVYVNDAR-QSSLSASSFVTTLWPLNASS-----NKLTVNFTDQHLLSPEEKQ---IRIAIVAVSI 2273
            GN L +V  +  L  L+  +H     S+   +  + T+  + Q+ ++ P QW+SV +    + F     L +S +  + +  PIL+LVHG I     +D W+D++  CV E V ++    Q +LS   FVTT++PL  +S     +++++NF  + + S    +   + I IVAV++
Sbjct:  721 GNALPSVDSLRRLHELIVAHHARLSMSVTNLVRTWLTRADLVQVGLVSPCQWISVRQCSASVKFSWPNELSNSKLQPSRVVAPILILVHGRIAPPACYDVWMDDDGPCVIERVCLDQTYIQRALSRMPFVTTVYPLGWNSLKPQEHEVSINFKPESISSIHSTRPTCVAIMIVAVAL 897

[Close]

BLAST of Chromobox protein vs. TrEMBL
Match: A0A2H1C1H2 (Chromo' (CHRromatin Organization MOdifier) domain protein OS=Fasciola hepatica OX=6192 GN=D915_11793 PE=4 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 1.352e-24
Identity = 68/166 (40.96%), Postives = 93/166 (56.02%), Query Frame = 3

Query:  357 TDNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVL-------------------DLIEDFKNKISDDKF---------------------EEXXXXXXX-----XXXXXXXGCYEYVPSNKVVATKTKYFDDIRDGKIDLTKNDLYSRVKTRKRL 719
            +D+ Y+VE I+G ++  G+ ++KV+WQG+    DSWEPEENL+NVL                   DL +DF +  ++                        EE    S         +SR+SG YEYVP +++VA+KTKYFDDIRDGKIDL+ NDLYSRVKTR+R+
Sbjct:   52 SDSVYLVENILGERIVKGQKFYKVRWQGFPPEADSWEPEENLSNVLEAINLYHRRQTEELTNTGTDLTKDFPSVCANSPASVPTPPSTPGCSQTKRLRGGSEERHSHSLGIKRKHGPKSRSSGRYEYVPKHELVASKTKYFDDIRDGKIDLSSNDLYSRVKTRRRM 217

[Close]

BLAST of Chromobox protein vs. TrEMBL
Match: A0A0R3WEK2 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS9255 PE=4 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 1.422e-23
Identity = 64/144 (44.44%), Postives = 81/144 (56.25%), Query Frame = 3

Query:  360 DNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDFKNKI-----------------------SDDKFEEXXXXXXXXXXXXXXGCYEYVPSNKVVATKTKYFDDIRDGKIDLTKNDLYSRVKTRKRLH 722
            D  Y+V+ I+  +    + Y+KV+W G+  SEDSWEPE NLT V +LI +F  K                        S    ++    S   M    +G +EYV  +++VATKTKYFDDIRDGKIDLT NDLYSRVKTRKR H
Sbjct:   15 DETYLVDSIIDERYIKNQKYYKVRWHGFPPSEDSWEPEANLTGVRELIREFHLKKKSSSTSRQHSSAKKRPELSSEAHSSKSVQDPPSPSKRRMTKSRTGHFEYVLQSELVATKTKYFDDIRDGKIDLTSNDLYSRVKTRKRCH 158

[Close]

BLAST of Chromobox protein vs. TrEMBL
Match: Q5DBZ5 (SJCHGC05321 protein OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 1.895e-23
Identity = 67/173 (38.73%), Postives = 94/173 (54.34%), Query Frame = 3

Query:  348 DSRTDNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDF----------------------------------------KNKI---SDDKFEEXXXXXXXXXXXXXXGCYEYVPSNKVVATKTKYFDDIRDGKIDLTKNDLYSRVKTRKRLHLEEGS 737
            ++ +   YIVE I   K+  G+ Y+KV+W+G+    DSWEPE NLT+VL++I +F                                         N++   S+++  ++S    +  +SR SG YEYVP +++VA+KTKYFDDIRDGKIDL  NDLYSRVKTR+R   E  S
Sbjct:   45 NAESGEVYIVESIRDEKIIKGQKYYKVRWRGFPPEADSWEPERNLTSVLNIISEFHSSKSKISKSLDMQKNYKAANSPASVPTPPATPNLLLQNLPNRLRGSSEERQLDNSAKRKHCAKSRTSGRYEYVPKHQLVASKTKYFDDIRDGKIDLCSNDLYSRVKTRRRCAAESAS 217

[Close]

BLAST of Chromobox protein vs. TrEMBL
Match: A0A5K3FU77 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 116.316 bits (290), Expect = 3.652e-23
Identity = 61/142 (42.96%), Postives = 83/142 (58.45%), Query Frame = 3

Query:  360 DNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDFKNKI-----------------------SDDKFEEXXXXXXXXXXXXXXGCYEYVPSNKVVATKTKYFDDIRDGKIDLTKNDLYSRVKTRKR 716
            D  YIVE I+G ++   + ++KV+W+G+  +EDSWEPE NL++V  LI+ F+ K                        S+    +S  +    M     G +EYVP N++VA KTKYFDDIR+GKIDL  NDLYSRVKTR+R
Sbjct:   15 DGVYIVESIIGERVVKKQRFYKVRWEGFSPNEDSWEPESNLSSVRALIKKFQLKQQSISTLRQRSSKKGHSQSVIEQNSNKPNRKSLHLHKRRMTKSRVGHFEYVPQNELVAAKTKYFDDIRNGKIDLISNDLYSRVKTRRR 156

[Close]

BLAST of Chromobox protein vs. Ensembl Cavefish
Match: ANKRD50 (ankyrin repeat domain 50 [Source:NCBI gene;Acc:103026486])

HSP 1 Score: 63.929 bits (154), Expect = 8.199e-10
Identity = 38/92 (41.30%), Postives = 52/92 (56.52%), Query Frame = 3

Query: 1461 ECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTD-YRIKSRTALYFAIENGRVDVVSMLLKFG 1733
            +C+TPL +A  +  V++V LLL  GA  D TDN +  TPL+ A+S+G+   V  LL + A  D    + RT L  A   G V+VV  LL  G
Sbjct:  741 DCMTPLLVAAYEGHVDVVDLLLEGGADVDHTDN-NGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRG 831

[Close]

BLAST of Chromobox protein vs. Ensembl Cavefish
Match: kidins220b (kinase D interacting substrate 220 [Source:NCBI gene;Acc:103040274])

HSP 1 Score: 62.7734 bits (151), Expect = 1.685e-9
Identity = 36/91 (39.56%), Postives = 55/91 (60.44%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTN 1739
            TPL LA  +  + I++ L+R GA  +  D+ D  + LI A+  G++  VK LLD SA+ ++R +   TAL +A   GRV+V  +LL+ G N
Sbjct:   48 TPLMLAAEQGSLEIIQELIRRGANVNL-DDVDCWSALISAAKEGHVEVVKELLDSSAYIEHRDMGGWTALMWAAYKGRVEVTKVLLENGAN 137

[Close]

BLAST of Chromobox protein vs. Ensembl Cavefish
Match: kidins220b (kinase D interacting substrate 220 [Source:NCBI gene;Acc:103040274])

HSP 1 Score: 62.7734 bits (151), Expect = 1.716e-9
Identity = 36/91 (39.56%), Postives = 55/91 (60.44%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTN 1739
            TPL LA  +  + I++ L+R GA  +  D+ D  + LI A+  G++  VK LLD SA+ ++R +   TAL +A   GRV+V  +LL+ G N
Sbjct:   48 TPLMLAAEQGSLEIIQELIRRGANVNL-DDVDCWSALISAAKEGHVEVVKELLDSSAYIEHRDMGGWTALMWAAYKGRVEVTKVLLENGAN 137

[Close]

BLAST of Chromobox protein vs. Ensembl Cavefish
Match: kidins220b (kinase D interacting substrate 220 [Source:NCBI gene;Acc:103040274])

HSP 1 Score: 62.7734 bits (151), Expect = 1.729e-9
Identity = 36/91 (39.56%), Postives = 55/91 (60.44%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTN 1739
            TPL LA  +  + I++ L+R GA  +  D+ D  + LI A+  G++  VK LLD SA+ ++R +   TAL +A   GRV+V  +LL+ G N
Sbjct:   40 TPLMLAAEQGSLEIIQELIRRGANVNL-DDVDCWSALISAAKEGHVEVVKELLDSSAYIEHRDMGGWTALMWAAYKGRVEVTKVLLENGAN 129

[Close]

BLAST of Chromobox protein vs. Ensembl Cavefish
Match: psmd10 (proteasome 26S subunit, non-ATPase 10 [Source:NCBI gene;Acc:103037594])

HSP 1 Score: 58.9214 bits (141), Expect = 2.072e-9
Identity = 35/93 (37.63%), Postives = 53/93 (56.99%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTNFY 1745
            TPL  A +KN+  I  LLL  GA P+ TD  ++ TPL  AS+ G    ++ LL  SA T+ +  +  TAL+ A +  RV+   +L++ G + Y
Sbjct:   75 TPLHYAASKNQYEIALLLLENGADPNATDKLES-TPLHRASAKGNYRLIQLLLKQSASTNIQDSEGNTALHLACDEERVEAAKLLVEHGASIY 166

[Close]

BLAST of Chromobox protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.9954 bits (136), Expect = 1.556e-8
Identity = 34/96 (35.42%), Postives = 54/96 (56.25%), Query Frame = 3

Query: 1455 TPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKS-RTALYFAIENGRVDVVSMLLKFGTN 1739
            T   LTP+ +A     +N+V+LLL+ GA  + T N   ETPL +AS  G +  VK LL   A    + +  +T L+ A   G+ ++V +LL+ G++
Sbjct:  400 TESGLTPIHVASFMGHLNVVQLLLQNGASSNAT-NVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSD 494

HSP 2 Score: 55.0694 bits (131), Expect = 6.412e-8
Identity = 31/90 (34.44%), Postives = 54/90 (60.00%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDY-RIKSRTALYFAIENGRVDVVSMLLKFGT 1736
            TPL +A  KNR+ ++ LLL++GA    T  +   TP+ +AS +G+++ V+ LL   A ++   ++  T L+ A   G+++VV  LL+ G 
Sbjct:  372 TPLHIACKKNRIKVMELLLKHGASIHTTTESGL-TPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGA 460

HSP 3 Score: 48.9062 bits (115), Expect = 5.440e-6
Identity = 33/87 (37.93%), Postives = 46/87 (52.87%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLK 1727
            TPL +A     +N+  LLL  GA  DFT   +  TPL +A+  G  + VK LLD  A  D + +   T L+ A  +G   V+ MLL+
Sbjct:  207 TPLHIAAHYGNMNVATLLLNLGAAVDFTAR-NGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLE 292

[Close]

BLAST of Chromobox protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000093.1 (pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000093.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.9954 bits (136), Expect = 1.634e-8
Identity = 34/96 (35.42%), Postives = 54/96 (56.25%), Query Frame = 3

Query: 1455 TPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKS-RTALYFAIENGRVDVVSMLLKFGTN 1739
            T   LTP+ +A     +N+V+LLL+ GA  + T N   ETPL +AS  G +  VK LL   A    + +  +T L+ A   G+ ++V +LL+ G++
Sbjct:  407 TESGLTPIHVASFMGHLNVVQLLLQNGASSNAT-NVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSD 501

HSP 2 Score: 54.6842 bits (130), Expect = 7.839e-8
Identity = 31/90 (34.44%), Postives = 54/90 (60.00%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDY-RIKSRTALYFAIENGRVDVVSMLLKFGT 1736
            TPL +A  KNR+ ++ LLL++GA    T  +   TP+ +AS +G+++ V+ LL   A ++   ++  T L+ A   G+++VV  LL+ G 
Sbjct:  379 TPLHIACKKNRIKVMELLLKHGASIHTTTESGL-TPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGA 467

HSP 3 Score: 49.2914 bits (116), Expect = 4.291e-6
Identity = 34/92 (36.96%), Postives = 47/92 (51.09%), Query Frame = 3

Query: 1455 TPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLK 1727
            T    TPL +A     +N+  LLL  GA  DFT   +  TPL +A+  G  + VK LLD  A  D + +   T L+ A  +G   V+ MLL+
Sbjct:  209 TESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTAR-NGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLE 299

[Close]

BLAST of Chromobox protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002048.1 (pep scaffold:Pmarinus_7.0:GL477431:30859:73495:1 gene:ENSPMAG00000001850.1 transcript:ENSPMAT00000002048.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.225 bits (134), Expect = 3.114e-8
Identity = 38/112 (33.93%), Postives = 58/112 (51.79%), Query Frame = 3

Query: 1416 LQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR---TALYFAIENGRVDVVSMLLKFGTNF 1742
            L NG   +   + T +  TPL LA +  R  +V LL+  GA  +  + +D  TPL LA+S GY++ +K LL+  A  + R  S+   + L  A  NG    V +LL  G++ 
Sbjct:  986 LDNGADIEAQSERTKD--TPLSLACSGGRQEVVELLIARGANKEHRNVSD-YTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDI 1094

HSP 2 Score: 52.7582 bits (125), Expect = 3.647e-7
Identity = 36/113 (31.86%), Postives = 55/113 (48.67%), Query Frame = 3

Query: 1467 LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSA-FTDYRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGN 1802
            +TPL  A +   V+IVRLLL +GA  +   +T   T L  A + GY+  V+ LL+  A   D+     T L  A   G V+V  +LL+ G      ++    S+L    + G+
Sbjct:  168 ITPLMAAASGGFVDIVRLLLAHGADVNAQSST-GNTALTYACAGGYVDVVRVLLEAGANLEDHNESGHTPLMEAASGGHVEVARLLLERGAGINTHSNEFKESALTLACYKGH 279

HSP 3 Score: 51.6026 bits (122), Expect = 8.665e-7
Identity = 47/172 (27.33%), Postives = 75/172 (43.60%), Query Frame = 3

Query: 1329 IDSDLISIDNFEDLKCSILMDKYH--LLHNALQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLKFGTNF-YRIADNLSGSSLINDMFMGNRLSNVVYVDL 1832
            +D D I  ++  D   ++     H  L+   +  G   +  +K   +  TPL LA T   VN+V LLL  GA  +       +TPL LA S G    V+ L+   A  ++R +   T L  A   G V+++ +LL  G     R    L  S L+     G+  +  + +D+
Sbjct:  922 VDIDCIHTESNHDTALTLACAGGHEDLVTVLIARGANIEHRDK---KGFTPLILAATAGHVNVVELLLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLIARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDM 1090

HSP 4 Score: 49.6766 bits (117), Expect = 3.145e-6
Identity = 33/98 (33.67%), Postives = 50/98 (51.02%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRI-KSRTALYFAIENGRVDVVSMLLKFGTNFYRIADN 1760
            TPL  A +   V + RLLL  GA  +   N   E+ L LA   G++  V+ LL+  A  +++  +  TAL  A  +G V+V  +LL+ G      AD+
Sbjct:  235 TPLMEAASGGHVEVARLLLERGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLESGAQVNMPADS 332

[Close]

BLAST of Chromobox protein vs. Ensembl Sea Lamprey
Match: anks1b (ankyrin repeat and sterile alpha motif domain containing 1B [Source:NCBI gene;Acc:565408])

HSP 1 Score: 54.6842 bits (130), Expect = 8.844e-8
Identity = 45/126 (35.71%), Postives = 65/126 (51.59%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLLALLR 1847
            TPL LA    R+++V LL R   P     NT   TPL LA+  G+   V+ LL+     + + +  +AL+ A   GRVDVV +LL+ G N   I D  S ++L  D+   +R    + +   ALLR
Sbjct:  161 TPLDLAALYGRLDVVTLLTR-SHPNLLACNTKQHTPLHLAARNGHTGTVQVLLEAGMDVNIQSEKGSALHEAALFGRVDVVRLLLEAGINV-NIRDKQSKTAL--DILGEHRSQKALQIS--ALLR 280

[Close]

BLAST of Chromobox protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007449.1 (pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007449.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.299 bits (129), Expect = 1.162e-7
Identity = 36/128 (28.12%), Postives = 66/128 (51.56%), Query Frame = 3

Query: 1347 SIDNFEDLKCSILMDKYHLLHNALQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLK 1727
            +++ F  L  +   ++  ++   L+ G      E  T   LTP+ ++     +NIV +LL+ GA P+ T N   ET L +A+  G    V++LL   A  D + +  +T L+ A   G++++V +LL+
Sbjct:   12 ALNGFTPLHIACKKNRIRVMELLLKYGASI---EAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNAT-NVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQ 135

HSP 2 Score: 53.1434 bits (126), Expect = 2.456e-7
Identity = 37/121 (30.58%), Postives = 64/121 (52.89%), Query Frame = 3

Query: 1377 SILMDKYHLLHNALQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLKFGT 1736
            S+L+ +Y  +++A ++G             L+PL LA  +++VN+  +L+++GA  + T      TPLI+A   G I  V  LL + A  + + K   T L+ A + G   +V++LLK G 
Sbjct:  296 SLLLARYADVNHATKSG-------------LSPLHLAAQEDKVNVAEILVKHGAHVNATTKL-GYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGA 402

HSP 3 Score: 51.9878 bits (123), Expect = 6.048e-7
Identity = 30/90 (33.33%), Postives = 51/90 (56.67%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDY-RIKSRTALYFAIENGRVDVVSMLLKFGT 1736
            TPL +A  KNR+ ++ LLL+YGA  +    +   TP+ +++ +G ++ V  LL   A  +   ++  TAL+ A   G+ +VV  LL+ G 
Sbjct:   17 TPLHIACKKNRIRVMELLLKYGASIEAVTESGL-TPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGA 105

HSP 4 Score: 49.2914 bits (116), Expect = 4.165e-6
Identity = 34/105 (32.38%), Postives = 57/105 (54.29%), Query Frame = 3

Query: 1416 LQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLK 1727
            L+NG + D   +   E  TPL +A    ++ IV+LLL++ A PD    ++  TPL +A+  G+      LL++ A      K   T L+ A + G+++V S+LL+
Sbjct:  101 LRNGAQVDAKAR---EEQTPLHIAARLGKLEIVQLLLQHMASPD-AATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQ 201

[Close]

BLAST of Chromobox protein vs. Ensembl Nematostella
Match: EDO34862 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN63])

HSP 1 Score: 46.2098 bits (108), Expect = 2.939e-6
Identity = 30/92 (32.61%), Postives = 44/92 (47.83%), Query Frame = 3

Query: 1467 LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKS-RTALYFAIENGRVDVVSMLLKFGTN 1739
            +TPL LA  K    ++  LLR GA  +  D     +PL  A   G  H ++ LL   A  + R  S  TA++ A      +VVS+L  +G +
Sbjct:    6 MTPLHLATLKGNRELITELLRMGADLNVEDGNSGRSPLHHAVESGRYHVIEFLLSRGALVNQRTFSGNTAMHTAAGRQMDEVVSLLASYGAD 97

[Close]

BLAST of Chromobox protein vs. Ensembl Nematostella
Match: EDO38725 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC11])

HSP 1 Score: 48.1358 bits (113), Expect = 4.148e-6
Identity = 31/87 (35.63%), Postives = 43/87 (49.43%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYR-IKSRTALYFAIENGRVDVVSMLLK 1727
            TPL +A  K  + + RLL+  GA  D   N   ETPL +A+ +G   A+K LL      D R    RT    A+  GR +   +LL+
Sbjct:   38 TPLHVACKKGSMEVGRLLVEKGAALD-KKNDKGETPLHMAACIGSFDALKFLLSKGVAIDERDFSHRTPFLSAVAAGRTENAMLLLE 123

[Close]

BLAST of Chromobox protein vs. Ensembl Nematostella
Match: EDO27150 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TA22])

HSP 1 Score: 43.8986 bits (102), Expect = 6.316e-6
Identity = 19/60 (31.67%), Postives = 38/60 (63.33%), Query Frame = 3

Query:  354 RTDNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLD--LIEDFKNKIS 527
            R    Y  E I+  ++ +GK ++ ++W+GY +  ++WEPEE   NVLD  L++ ++ +++
Sbjct:    6 RAAGIYAAETILKERVRDGKVWYFIKWKGYSQRYNTWEPEE---NVLDPRLLKAYQERLA 62

[Close]

BLAST of Chromobox protein vs. Ensembl Nematostella
Match: EDO39112 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB40])

HSP 1 Score: 48.9062 bits (115), Expect = 8.027e-6
Identity = 36/93 (38.71%), Postives = 48/93 (51.61%), Query Frame = 3

Query: 1467 LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTNF 1742
            LT L +A    R    RLLL  GA  D+ D+ +  TPL   +S+G    VK LL+Y A  + R K+R T L  A   GR++V   LL  G + 
Sbjct:  107 LTALHIAAAAARTEACRLLLEKGAEVDYRDD-ERLTPLFYVASVGCPLTVKVLLEYDADLEARDKNRKTPLISAAYFGRLEVFRTLLDSGADI 198

[Close]

BLAST of Chromobox protein vs. Ensembl Medaka
Match: ank1b (ankyrin-1 [Source:NCBI gene;Acc:101157380])

HSP 1 Score: 59.6918 bits (143), Expect = 1.428e-8
Identity = 46/141 (32.62%), Postives = 69/141 (48.94%), Query Frame = 3

Query: 1416 LQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSA-FTDYRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLL 1835
            LQN  + D   K   +  TPL  A       +V+LLL + A PD +  T   TPL +A+  G+IH ++ LLD  A       K  T L+ A + G+VDV  +LL+ G N      N +G + +  + +    +N+  V LL
Sbjct:  455 LQNAAQVDARAK---DDQTPLHCAARMGHKELVKLLLDHKANPD-SATTAGHTPLHIAAREGHIHTIRILLDAGAQQVKMTKKGFTPLHVASKYGKVDVAELLLERGAN-----PNAAGKNGLTPLHVAVHHNNLDVVKLL 586

HSP 2 Score: 56.6102 bits (135), Expect = 1.178e-7
Identity = 37/99 (37.37%), Postives = 52/99 (52.53%), Query Frame = 3

Query: 1446 EKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLKFGTN 1739
            E  T   LTPL +A     +NIV+ LL+ GA P+ + N   ETPL +AS  G+    + LL  +A  D R K  +T L+ A   G  ++V +LL    N
Sbjct:  396 EAVTESGLTPLHVAAFMGHLNIVKNLLQRGASPNAS-NVKVETPLHMASRAGHCEVAQFLLQNAAQVDARAKDDQTPLHCAARMGHKELVKLLLDHKAN 493

HSP 3 Score: 53.5286 bits (127), Expect = 1.170e-6
Identity = 44/147 (29.93%), Postives = 70/147 (47.62%), Query Frame = 3

Query: 1467 LTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIK-SRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLLAL-----LRTYHMSFINSLNRTI 1889
            LTPL L   +  V I   L++ GA   +  +    TPL +A   G I  VK LL   A  + + +   T L+ A + G  D+V++LLK G     I  N  G+S    + +  RL  +  +D+L L     + T+ MSF  +++  +
Sbjct:  667 LTPLHLVAQEGHVGIADTLVKQGAS-VYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNAKTRMGYTPLHQAAQQGHTDIVTLLLKHGALPNEITSN--GTS---PLGIAKRLGYISVIDVLKLVTEESVSTHRMSFPETVDEIL 807

HSP 4 Score: 51.2174 bits (121), Expect = 5.749e-6
Identity = 45/160 (28.12%), Postives = 75/160 (46.88%), Query Frame = 3

Query: 1263 LHVYSKN--IRQGTVCTFNMPKVQIDSDLISIDNFEDLKCSILMDKYHLLHNALQNGVRFDWNEKFTPE-CLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKF 1730
            LH+ ++N   R   V   N P    + D++S   F  L  +   +   +    L  G     N  FTP+  +TPL +A  +  V +VRLLL  GA  D     D  TPL  A+  G++  ++ LL++ A    + K+  + ++ A +   +D V  LL++
Sbjct:  175 LHIAARNDDTRTAAVLLQNDP----NPDVLSKTGFTPLHIAAHYENMSVAQLLLNRGA----NVNFTPKNGITPLHIASRRGNVMMVRLLLDRGAQID-AQTKDELTPLHCAARNGHVRIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQY 325

[Close]

BLAST of Chromobox protein vs. Ensembl Medaka
Match: ENSORLT00000041917.1 (pep primary_assembly:ASM223467v1:19:16436475:16453404:1 gene:ENSORLG00000026670.1 transcript:ENSORLT00000041917.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 57.3806 bits (137), Expect = 1.540e-8
Identity = 38/100 (38.00%), Postives = 54/100 (54.00%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSG 1769
            TPL ++    + +IV+LLL  GA PD T N+   TPL LA+  G+     ALLD  A     +   T L+ A + G VD+V++LL  G+   R   +L G
Sbjct:   83 TPLHISSRLGKQDIVQLLLTNGADPDATTNS-GYTPLHLAAREGHKDIAAALLDQGA----NLSGITPLHLAAQEGSVDIVTLLLARGSPINRPLCHLVG 177

[Close]

BLAST of Chromobox protein vs. Ensembl Medaka
Match: ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A [Source:NCBI gene;Acc:101163740])

HSP 1 Score: 56.9954 bits (136), Expect = 9.905e-8
Identity = 40/98 (40.82%), Postives = 52/98 (53.06%), Query Frame = 3

Query: 1443 NEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTD-NTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTALYFAIENGRVDVVSMLLKFG 1733
            N KF     TPL LA    R+ +V+LLLR  A P+    NT   TPL LAS  G++  V+ LLD     +Y  +  +AL+ A   G+ DVV  LL  G
Sbjct:  191 NNKFE----TPLDLAALYGRLEVVKLLLR--AHPNLLHCNTKKHTPLHLASRNGHLSVVEVLLDAGMDINYETEKGSALHEAGLFGKADVVQKLLNAG 282

[Close]

BLAST of Chromobox protein vs. Ensembl Medaka
Match: ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A [Source:NCBI gene;Acc:101163740])

HSP 1 Score: 56.6102 bits (135), Expect = 1.048e-7
Identity = 40/98 (40.82%), Postives = 52/98 (53.06%), Query Frame = 3

Query: 1443 NEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTD-NTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTALYFAIENGRVDVVSMLLKFG 1733
            N KF     TPL LA    R+ +V+LLLR  A P+    NT   TPL LAS  G++  V+ LLD     +Y  +  +AL+ A   G+ DVV  LL  G
Sbjct:  191 NNKFE----TPLDLAALYGRLEVVKLLLR--AHPNLLHCNTKKHTPLHLASRNGHLSVVEVLLDAGMDINYETEKGSALHEAGLFGKADVVQKLLNAG 282

[Close]

BLAST of Chromobox protein vs. Ensembl Medaka
Match: ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A [Source:NCBI gene;Acc:101163740])

HSP 1 Score: 56.6102 bits (135), Expect = 1.107e-7
Identity = 40/98 (40.82%), Postives = 52/98 (53.06%), Query Frame = 3

Query: 1443 NEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTD-NTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTALYFAIENGRVDVVSMLLKFG 1733
            N KF     TPL LA    R+ +V+LLLR  A P+    NT   TPL LAS  G++  V+ LLD     +Y  +  +AL+ A   G+ DVV  LL  G
Sbjct:  191 NNKFE----TPLDLAALYGRLEVVKLLLR--AHPNLLHCNTKKHTPLHLASRNGHLSVVEVLLDAGMDINYETEKGSALHEAGLFGKADVVQKLLNAG 282

[Close]

BLAST of Chromobox protein vs. Planmine SMEST
Match: SMESG000047257.1 (SMESG000047257.1)

HSP 1 Score: 1303.12 bits (3371), Expect = 0.000e+0
Identity = 700/701 (99.86%), Postives = 700/701 (99.86%), Query Frame = 3

Query:  177 MSARKQGKNNKRHFHEQVDSFDDKKKNINLSHCEVEXXXXXXXXXXXXXXXXXXXXQDSRTDNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDFKNKISDDKFEEXXXXXXXXXXXXXXGCYEYVPSNKVVATKTKYFDDIRDGKIDLTKNDLYSRVKTRKRLHLEEGSDKPXXXXXXXXXXXXXXXXXXXXXXXXXXXDVPISFEKNKFYQSNLFEMTAEFMKTGSFKKSQNTIASKSSSNDDISLFNYSISPNTNQSDDFPVQISPAHVINIESSKQSVYTQTISTDFEVQESIIQKEETESKLINPTLSVKPHVQKIIDKIDQSFEKPSFQKRFVTNDTDLLHVYSKNIRQGTVCTFNMPKVQIDSDLISIDNFEDLKCSILMDKYHLLHNALQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLLALLRTYHMSFINSLNRTITRYFTKHFIKQICIIFPHQWVSVLEKEFHIDFLLDSSIMTNIDTPILLLVHGIQADCDFDFWLDNNCCCVESVYVNDARQSSLSASSFVTTLWPLNASSNKLTVNFTDQHLLSPEEKQIRIAIVAVSIDC 2279
            MSARKQGKNNKRHFHEQVDSFDDKKKNINLSHCEVESRSSSCCSKRSNKKSNNKKSQDSRTDNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDFKNKISDDKFEESSRISNNIMRSRNSGCYEYVPSNKVVATKTKYFDDIRDGKIDLTKNDLYSRVKTRKRLHLEEGSDKPIESTENETDNITIEETTEVVETAIKTEDVPISFEKNKFYQSNLFEMTAEFMKTGSFKKSQNTIASKSSSNDDISLFNYSISPNTNQSDDFPVQISPAHVINIESSKQSVYTQTISTDFEVQESIIQKEETESKLINPTLSVKPHVQKIIDKIDQSFEKPS QKRFVTNDTDLLHVYSKNIRQGTVCTFNMPKVQIDSDLISIDNFEDLKCSILMDKYHLLHNALQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLLALLRTYHMSFINSLNRTITRYFTKHFIKQICIIFPHQWVSVLEKEFHIDFLLDSSIMTNIDTPILLLVHGIQADCDFDFWLDNNCCCVESVYVNDARQSSLSASSFVTTLWPLNASSNKLTVNFTDQHLLSPEEKQIRIAIVAVSIDC
Sbjct:    1 MSARKQGKNNKRHFHEQVDSFDDKKKNINLSHCEVESRSSSCCSKRSNKKSNNKKSQDSRTDNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDFKNKISDDKFEESSRISNNIMRSRNSGCYEYVPSNKVVATKTKYFDDIRDGKIDLTKNDLYSRVKTRKRLHLEEGSDKPIESTENETDNITIEETTEVVETAIKTEDVPISFEKNKFYQSNLFEMTAEFMKTGSFKKSQNTIASKSSSNDDISLFNYSISPNTNQSDDFPVQISPAHVINIESSKQSVYTQTISTDFEVQESIIQKEETESKLINPTLSVKPHVQKIIDKIDQSFEKPSLQKRFVTNDTDLLHVYSKNIRQGTVCTFNMPKVQIDSDLISIDNFEDLKCSILMDKYHLLHNALQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLLALLRTYHMSFINSLNRTITRYFTKHFIKQICIIFPHQWVSVLEKEFHIDFLLDSSIMTNIDTPILLLVHGIQADCDFDFWLDNNCCCVESVYVNDARQSSLSASSFVTTLWPLNASSNKLTVNFTDQHLLSPEEKQIRIAIVAVSIDC 701

[Close]

BLAST of Chromobox protein vs. Planmine SMEST
Match: SMESG000065471.1 (SMESG000065471.1)

HSP 1 Score: 1302.35 bits (3369), Expect = 0.000e+0
Identity = 700/701 (99.86%), Postives = 700/701 (99.86%), Query Frame = 3

Query:  177 MSARKQGKNNKRHFHEQVDSFDDKKKNINLSHCEVEXXXXXXXXXXXXXXXXXXXXQDSRTDNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDFKNKISDDKFEEXXXXXXXXXXXXXXGCYEYVPSNKVVATKTKYFDDIRDGKIDLTKNDLYSRVKTRKRLHLEEGSDKPXXXXXXXXXXXXXXXXXXXXXXXXXXXDVPISFEKNKFYQSNLFEMTAEFMKTGSFKKSQNTIASKSSSNDDISLFNYSISPNTNQSDDFPVQISPAHVINIESSKQSVYTQTISTDFEVQESIIQKEETESKLINPTLSVKPHVQKIIDKIDQSFEKPSFQKRFVTNDTDLLHVYSKNIRQGTVCTFNMPKVQIDSDLISIDNFEDLKCSILMDKYHLLHNALQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLLALLRTYHMSFINSLNRTITRYFTKHFIKQICIIFPHQWVSVLEKEFHIDFLLDSSIMTNIDTPILLLVHGIQADCDFDFWLDNNCCCVESVYVNDARQSSLSASSFVTTLWPLNASSNKLTVNFTDQHLLSPEEKQIRIAIVAVSIDC 2279
            MSARKQGKNNKRHFHEQVDSFDDKKKNINLSHCEVESRSSSCCSKRSNKKSNNKKSQDSRTDNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDFKNKISDDKFEESSRISNNIMRSRNSGCYEYVPSNKVVATKTKYFDDIRDGKIDLTKNDLYSRVKTRKRLHLEEGSDKPIESTENETDNITIEETTEVVETAIKTEDVPISFEKNK YQSNLFEMTAEFMKTGSFKKSQNTIASKSSSNDDISLFNYSISPNTNQSDDFPVQISPAHVINIESSKQSVYTQTISTDFEVQESIIQKEETESKLINPTLSVKPHVQKIIDKIDQSFEKPSFQKRFVTNDTDLLHVYSKNIRQGTVCTFNMPKVQIDSDLISIDNFEDLKCSILMDKYHLLHNALQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLLALLRTYHMSFINSLNRTITRYFTKHFIKQICIIFPHQWVSVLEKEFHIDFLLDSSIMTNIDTPILLLVHGIQADCDFDFWLDNNCCCVESVYVNDARQSSLSASSFVTTLWPLNASSNKLTVNFTDQHLLSPEEKQIRIAIVAVSIDC
Sbjct:    1 MSARKQGKNNKRHFHEQVDSFDDKKKNINLSHCEVESRSSSCCSKRSNKKSNNKKSQDSRTDNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEENLTNVLDLIEDFKNKISDDKFEESSRISNNIMRSRNSGCYEYVPSNKVVATKTKYFDDIRDGKIDLTKNDLYSRVKTRKRLHLEEGSDKPIESTENETDNITIEETTEVVETAIKTEDVPISFEKNKCYQSNLFEMTAEFMKTGSFKKSQNTIASKSSSNDDISLFNYSISPNTNQSDDFPVQISPAHVINIESSKQSVYTQTISTDFEVQESIIQKEETESKLINPTLSVKPHVQKIIDKIDQSFEKPSFQKRFVTNDTDLLHVYSKNIRQGTVCTFNMPKVQIDSDLISIDNFEDLKCSILMDKYHLLHNALQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTALYFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYVDLLALLRTYHMSFINSLNRTITRYFTKHFIKQICIIFPHQWVSVLEKEFHIDFLLDSSIMTNIDTPILLLVHGIQADCDFDFWLDNNCCCVESVYVNDARQSSLSASSFVTTLWPLNASSNKLTVNFTDQHLLSPEEKQIRIAIVAVSIDC 701

[Close]

BLAST of Chromobox protein vs. Planmine SMEST
Match: SMESG000013006.1 (SMESG000013006.1)

HSP 1 Score: 65.0846 bits (157), Expect = 2.336e-10
Identity = 36/104 (34.62%), Postives = 60/104 (57.69%), Query Frame = 3

Query: 1431 RFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKS-RTALYFAIENGRVDVVSMLLKFGTN 1739
            + D NE   P+  TPL  A+  N  +IV LLL+ GA P+   +    TPL+ A+++GY + V+ LL+Y A  D +  +  TAL++A  +G  +   ++L + +N
Sbjct:   37 KCDVNE-IGPDGETPLTCAINANNYDIVELLLKSGADPNLRPDKVESTPLMDAANVGYKNIVQILLEYGANPDIKSSTNNTALHYAACSGHSECCKLILDYSSN 139

HSP 2 Score: 56.6102 bits (135), Expect = 9.752e-8
Identity = 36/92 (39.13%), Postives = 50/92 (54.35%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTNF 1742
            T L +A  K     V+LLL++GA  D + N   +TPL LA + GYI  V+ L+DY A  +     R T L  A + G + VV  L+K+ T F
Sbjct: 1414 TVLIIAADKGHTEFVKLLLKHGAIVD-SKNKKGDTPLWLACNGGYIDVVRLLIDYKADANSSDNRRMTCLMTAFKKGHIKVVKELVKYVTQF 1504

[Close]

BLAST of Chromobox protein vs. Planmine SMEST
Match: SMESG000013006.1 (SMESG000013006.1)

HSP 1 Score: 65.0846 bits (157), Expect = 2.500e-10
Identity = 36/104 (34.62%), Postives = 60/104 (57.69%), Query Frame = 3

Query: 1431 RFDWNEKFTPECLTPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKS-RTALYFAIENGRVDVVSMLLKFGTN 1739
            + D NE   P+  TPL  A+  N  +IV LLL+ GA P+   +    TPL+ A+++GY + V+ LL+Y A  D +  +  TAL++A  +G  +   ++L + +N
Sbjct:   37 KCDVNE-IGPDGETPLTCAINANNYDIVELLLKSGADPNLRPDKVESTPLMDAANVGYKNIVQILLEYGANPDIKSSTNNTALHYAACSGHSECCKLILDYSSN 139

HSP 2 Score: 56.6102 bits (135), Expect = 1.026e-7
Identity = 36/92 (39.13%), Postives = 50/92 (54.35%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSR-TALYFAIENGRVDVVSMLLKFGTNF 1742
            T L +A  K     V+LLL++GA  D + N   +TPL LA + GYI  V+ L+DY A  +     R T L  A + G + VV  L+K+ T F
Sbjct: 1412 TVLIIAADKGHTEFVKLLLKHGAIVD-SKNKKGDTPLWLACNGGYIDVVRLLIDYKADANSSDNRRMTCLMTAFKKGHIKVVKELVKYVTQF 1502

[Close]

BLAST of Chromobox protein vs. Planmine SMEST
Match: SMESG000000606.1 (SMESG000000606.1)

HSP 1 Score: 57.7658 bits (138), Expect = 4.705e-8
Identity = 34/90 (37.78%), Postives = 50/90 (55.56%), Query Frame = 3

Query: 1470 TPLQLAVTKNRVNIVRLLLRYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSA-FTDYRIKSRTALYFAIENGRVDVVSMLLKFGT 1736
            TPL +A  K+++ IV LLL+YGA  + T  T   TPL +++ +G   AV  LL   A      ++  TAL+ A  N + + V +LLK G 
Sbjct:  373 TPLHIACKKHKIKIVELLLKYGALIEATTET-GLTPLHVSAFIGSKEAVNMLLQKGANIEQGTMRGETALHLATRNNQTETVKLLLKAGA 461

The following BLAST results are available for this feature:

BLAST of Chromobox protein vs. Ensembl Human
BLAST of Chromobox protein vs. Ensembl Celegans
BLAST of Chromobox protein vs. Ensembl Fly
BLAST of Chromobox protein vs. Ensembl Zebrafish
BLAST of Chromobox protein vs. Ensembl Xenopus
BLAST of Chromobox protein vs. Ensembl Mouse
BLAST of Chromobox protein vs. UniProt/SwissProt
BLAST of Chromobox protein vs. TrEMBL
BLAST of Chromobox protein vs. Ensembl Cavefish
BLAST of Chromobox protein vs. Ensembl Sea Lamprey
BLAST of Chromobox protein vs. Ensembl Yeast
BLAST of Chromobox protein vs. Ensembl Nematostella
BLAST of Chromobox protein vs. Ensembl Medaka
BLAST of Chromobox protein vs. Planmine SMEST

BLAST of Chromobox protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ASB15	6.411e-9	38.71	ankyrin repeat and SOCS box containing 15 [Source:...	[more]
ANKRD50	1.067e-8	37.93	ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:H...	[more]
ANKRD50	1.109e-8	37.93	ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:H...	[more]
ANK2	1.499e-8	36.84	ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]	[more]
ANK2	1.499e-8	36.84	ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]	[more]

BLAST of Chromobox protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trp-4	8.328e-8	37.50	TRP (Transient receptor potential) channel family ...	[more]
hpl-2	3.826e-7	40.35	Chromo-domain protein; HP1 Like (Heterochromatin p...	[more]
unc-44	3.835e-7	32.26	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]
unc-44	3.835e-7	32.26	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]
unc-44	3.908e-7	32.26	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]

BLAST of Chromobox protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rhi	3.836e-8	38.46	gene:FBgn0004400 transcript:FBtr0086897	[more]
Ank2	9.100e-8	31.45	gene:FBgn0261788 transcript:FBtr0344224	[more]
Ank2	1.001e-7	31.45	gene:FBgn0261788 transcript:FBtr0303125	[more]
CG3104	1.262e-7	32.61	gene:FBgn0031473 transcript:FBtr0335132	[more]
CG3104	1.262e-7	32.61	gene:FBgn0031473 transcript:FBtr0077686	[more]

BLAST of Chromobox protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ANKRD50	5.206e-10	41.30	ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:H...	[more]
kidins220b	8.757e-9	39.56	kinase D-interacting substrate 220b [Source:NCBI g...	[more]
ankk1	9.177e-9	34.97	ankyrin repeat and kinase domain containing 1 [Sou...	[more]
asb2b	1.127e-8	32.85	ankyrin repeat and SOCS box containing 2b [Source:...	[more]
asb2b	1.969e-8	32.61	ankyrin repeat and SOCS box containing 2b [Source:...	[more]

BLAST of Chromobox protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gart	4.789e-9	34.85	phosphoribosylglycinamide formyltransferase, phosp...	[more]
ANK2	1.074e-8	36.84	ankyrin 2, neuronal [Source:NCBI gene;Acc:10049480...	[more]
ANK2	1.106e-8	36.84	ankyrin 2, neuronal [Source:NCBI gene;Acc:10049480...	[more]
ANK2	1.116e-8	36.84	ankyrin 2, neuronal [Source:NCBI gene;Acc:10049480...	[more]
ANK2	1.145e-8	36.84	ankyrin 2, neuronal [Source:NCBI gene;Acc:10049480...	[more]

BLAST of Chromobox protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ankrd50	7.252e-9	37.39	ankyrin repeat domain 50 [Source:MGI Symbol;Acc:MG...	[more]
Kidins220	1.100e-8	42.11	kinase D-interacting substrate 220 [Source:MGI Sym...	[more]
Kidins220	1.141e-8	42.11	kinase D-interacting substrate 220 [Source:MGI Sym...	[more]
Ank2	1.368e-8	36.84	ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]	[more]
Ank2	1.732e-8	36.84	ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]	[more]

BLAST of Chromobox protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9EQG6\|KDIS_RAT	1.233e-8	44.21	Kinase D-interacting substrate of 220 kDa OS=Rattu...	[more]
sp\|Q9ULJ7\|ANR50_HUMAN	5.323e-8	37.93	Ankyrin repeat domain-containing protein 50 OS=Hom...	[more]
sp\|Q7T163\|KDISB_DANRE	6.667e-8	39.56	Kinase D-interacting substrate of 220 kDa B OS=Dan...	[more]
sp\|Q96NW4\|ANR27_HUMAN	1.369e-7	29.29	Ankyrin repeat domain-containing protein 27 OS=Hom...	[more]
sp\|Q8NFD2\|ANKK1_HUMAN	1.592e-7	35.19	Ankyrin repeat and protein kinase domain-containin...	[more]

BLAST of Chromobox protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
G4V7S3	5.548e-25	40.68	Chromobox protein-related (Chromobox 1) (Heterochr...	[more]
A0A2H1C1H2	1.352e-24	40.96	Chromo' (CHRromatin Organization MOdifier) domain ...	[more]
A0A0R3WEK2	1.422e-23	44.44	Uncharacterized protein OS=Taenia asiatica OX=6051...	[more]
Q5DBZ5	1.895e-23	38.73	SJCHGC05321 protein OS=Schistosoma japonicum OX=61...	[more]
A0A5K3FU77	3.652e-23	42.96	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]

BLAST of Chromobox protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ANKRD50	8.199e-10	41.30	ankyrin repeat domain 50 [Source:NCBI gene;Acc:103...	[more]
kidins220b	1.685e-9	39.56	kinase D interacting substrate 220 [Source:NCBI ge...	[more]
kidins220b	1.716e-9	39.56	kinase D interacting substrate 220 [Source:NCBI ge...	[more]
kidins220b	1.729e-9	39.56	kinase D interacting substrate 220 [Source:NCBI ge...	[more]
psmd10	2.072e-9	37.63	proteasome 26S subunit, non-ATPase 10 [Source:NCBI...	[more]

BLAST of Chromobox protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000000095.1	1.556e-8	35.42	pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 g...	[more]
ENSPMAT00000000093.1	1.634e-8	35.42	pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 g...	[more]
ENSPMAT00000002048.1	3.114e-8	33.93	pep scaffold:Pmarinus_7.0:GL477431:30859:73495:1 g...	[more]
anks1b	8.844e-8	35.71	ankyrin repeat and sterile alpha motif domain cont...	[more]
ENSPMAT00000007449.1	1.162e-7	28.13	pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1...	[more]

BLAST of Chromobox protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Chromobox protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO34862	2.939e-6	32.61	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38725	4.148e-6	35.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27150	6.316e-6	31.67	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39112	8.027e-6	38.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Chromobox protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ank1b	1.428e-8	32.62	ankyrin-1 [Source:NCBI gene;Acc:101157380]	[more]
ENSORLT00000041917.1	1.540e-8	38.00	pep primary_assembly:ASM223467v1:19:16436475:16453...	[more]
ANKS1A	9.905e-8	40.82	ankyrin repeat and sterile alpha motif domain cont...	[more]
ANKS1A	1.048e-7	40.82	ankyrin repeat and sterile alpha motif domain cont...	[more]
ANKS1A	1.107e-7	40.82	ankyrin repeat and sterile alpha motif domain cont...	[more]

BLAST of Chromobox protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000047257.1	0.000e+0	99.86	SMESG000047257.1	[more]
SMESG000065471.1	0.000e+0	99.86	SMESG000065471.1	[more]
SMESG000013006.1	2.336e-10	34.62	SMESG000013006.1	[more]
SMESG000013006.1	2.500e-10	34.62	SMESG000013006.1	[more]
SMESG000000606.1	4.705e-8	37.78	SMESG000000606.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30004311 ID=SMED30004311|Name=Chromobox protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2623bp
TATTTATACTTTTGTTATTAAAAATTTAAATTTAATATTTTCTGATAATT
TTAAAAATGAATTATTGATAAATTAATTGATATTTTAATAATTTAAAATT
TAAATAAATCATGTTTTATAGTAAATCAAATTAGTTGAAGCCGTAATACA
GCTGTTAATCTATACTTATACGCACAATGTCTGCTAGAAAGCAAGGCAAA
AACAACAAAAGGCACTTTCATGAACAAGTGGATAGCTTTGATGACAAAAA
AAAGAATATAAATTTGTCGCATTGTGAAGTCGAAAGCCGAAGTAGTAGTT
GTTGTAGTAAAAGGTCTAATAAAAAATCAAATAATAAAAAGAGTCAAGAT
AGTCGAACTGATAATTTTTATATAGTTGAAAAAATAGTTGGTCATAAAAT
GTGTAACGGAAAGTCATATTTTAAAGTTCAGTGGCAGGGTTATGATGAAT
CAGAAGATAGTTGGGAACCCGAAGAAAATCTTACAAATGTTCTTGATTTA
ATTGAAGACTTTAAAAACAAAATATCTGATGATAAATTTGAAGAAAGTAG
TAGAATATCAAATAATATTATGCGATCGCGTAATTCTGGGTGTTATGAAT
ATGTTCCATCTAATAAAGTTGTAGCAACGAAAACCAAATATTTTGATGAC
ATTAGAGATGGGAAAATTGATTTAACTAAAAATGATCTTTATTCCCGAGT
GAAAACACGAAAAAGATTACATTTGGAAGAAGGTTCTGATAAGCCTATTG
AAAGTACAGAAAATGAGACAGACAATATAACTATTGAGGAAACAACGGAG
GTTGTTGAAACAGCTATAAAGACTGAAGATGTTCCAATTTCATTCGAAAA
AAATAAATTTTATCAATCAAATCTTTTTGAAATGACAGCGGAATTTATGA
AAACTGGTAGCTTCAAAAAATCACAAAATACAATAGCATCAAAATCATCA
TCGAATGATGATATCAGTTTATTTAATTACAGCATTTCACCTAATACTAA
TCAATCTGATGATTTTCCTGTCCAAATATCACCAGCACATGTCATTAATA
TTGAATCTTCAAAGCAGTCAGTGTACACTCAGACTATTTCTACAGATTTT
GAAGTTCAAGAATCTATTATTCAAAAAGAGGAAACGGAATCGAAATTGAT
AAATCCTACTCTCTCAGTGAAACCCCATGTTCAGAAAATAATAGATAAAA
TTGACCAATCATTTGAAAAGCCTTCATTTCAAAAAAGATTTGTGACCAAT
GACACTGATTTGCTTCATGTGTATTCTAAAAATATTAGACAAGGAACCGT
TTGTACTTTCAATATGCCAAAGGTTCAAATTGATTCCGACTTGATCAGTA
TTGACAATTTTGAGGACCTCAAATGTTCAATATTAATGGATAAGTATCAT
TTATTGCATAATGCTCTTCAAAATGGAGTCAGATTTGATTGGAATGAGAA
GTTCACACCCGAATGTTTAACTCCATTACAATTAGCTGTAACAAAAAACA
GAGTTAATATTGTTCGTTTGCTTCTCCGATATGGTGCTCCACCAGATTTC
ACTGACAACACAGACGCAGAAACGCCTCTAATATTGGCCTCGAGTTTAGG
TTACATTCACGCGGTGAAAGCGCTACTAGATTACAGTGCATTCACCGATT
ATAGAATCAAATCTCGGACCGCCCTTTATTTCGCCATTGAAAATGGTCGG
GTCGATGTTGTCAGCATGTTGCTCAAATTTGGCACGAATTTCTACAGAAT
TGCCGATAATCTTTCTGGGTCATCACTAATCAATGACATGTTTATGGGAA
ACCGATTATCTAATGTTGTTTATGTTGATTTGCTAGCATTATTGCGAACT
TACCACATGTCATTCATCAATTCTCTTAATCGTACAATTACTCGGTACTT
CACAAAACATTTTATTAAACAGATTTGCATAATATTTCCCCATCAATGGG
TCAGTGTGCTCGAGAAAGAATTCCACATTGATTTTCTCCTCGACAGTTCT
ATCATGACGAATATTGACACGCCAATTCTTTTGTTGGTACATGGCATTCA
AGCGGACTGTGATTTTGATTTCTGGTTGGATAACAACTGTTGTTGTGTTG
AGTCTGTGTATGTCAATGATGCTCGCCAGTCCAGTCTCAGTGCTTCGTCA
TTTGTCACGACGCTTTGGCCCCTCAATGCTTCTAGTAACAAATTGACAGT
CAATTTCACAGACCAGCATTTATTGTCACCGGAGGAAAAACAGATCCGGA
TCGCAATTGTTGCCGTGAGTATTGACTGCACCCGTTCGACAAGCACTGCC
ACCAGCAGCAACAACAGCAGCAACAACAACAACAGCAACAACAGTCACAA
GCTGGTAGACAATTTCATGATTTACAAAGACAATTTCAAAGACCAATGAA
AAATCAACAACAAAATTGGTCAAATCAATCATCTCAAGGACAGCAAGGGC
AACTTAATCATTCGTCAAATCAATAGTTATGTTTTCTGTAGAATAATATA
ATTAATTGTCTGTACACAATATTTCACATATTAATAAATCATTTAGTTCT
TCTTTGTTCAATAGTTACAGTTAATTTTTATTGTAGAAAAGTGAACATTT
TATTCATTATTGATTACAAGGGC

protein sequence of SMED30004311-orf-1

>SMED30004311-orf-1 ID=SMED30004311-orf-1|Name=SMED30004311-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=741bp
MSARKQGKNNKRHFHEQVDSFDDKKKNINLSHCEVESRSSSCCSKRSNKK
SNNKKSQDSRTDNFYIVEKIVGHKMCNGKSYFKVQWQGYDESEDSWEPEE
NLTNVLDLIEDFKNKISDDKFEESSRISNNIMRSRNSGCYEYVPSNKVVA
TKTKYFDDIRDGKIDLTKNDLYSRVKTRKRLHLEEGSDKPIESTENETDN
ITIEETTEVVETAIKTEDVPISFEKNKFYQSNLFEMTAEFMKTGSFKKSQ
NTIASKSSSNDDISLFNYSISPNTNQSDDFPVQISPAHVINIESSKQSVY
TQTISTDFEVQESIIQKEETESKLINPTLSVKPHVQKIIDKIDQSFEKPS
FQKRFVTNDTDLLHVYSKNIRQGTVCTFNMPKVQIDSDLISIDNFEDLKC
SILMDKYHLLHNALQNGVRFDWNEKFTPECLTPLQLAVTKNRVNIVRLLL
RYGAPPDFTDNTDAETPLILASSLGYIHAVKALLDYSAFTDYRIKSRTAL
YFAIENGRVDVVSMLLKFGTNFYRIADNLSGSSLINDMFMGNRLSNVVYV
DLLALLRTYHMSFINSLNRTITRYFTKHFIKQICIIFPHQWVSVLEKEFH
IDFLLDSSIMTNIDTPILLLVHGIQADCDFDFWLDNNCCCVESVYVNDAR
QSSLSASSFVTTLWPLNASSNKLTVNFTDQHLLSPEEKQIRIAIVAVSID
CTRSTSTATSSNNSSNNNNSNNSHKLVDNFMIYKDNFKDQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005768	endosome

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036770	Ankyrin_rpt-contain_sf
IPR002110	Ankyrin_rpt
IPR000953	Chromo/chromo_shadow_dom
IPR023780	Chromo_domain
IPR020683	Ankyrin_rpt-contain_dom
IPR016197	Chromo-like_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

Vocabulary: **biological process**
Term	Definition
GO:0006810	transport
GO:0006886	intracellular protein transport
GO:0015031	protein transport
GO:1990126	retrograde transport, endosome to plasma membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000953	Chromo/chromo shadow domain	SMART	SM00298	chromo_7	coord: 64..117 e-value: 2.4E-14 score: 63.7
IPR000953	Chromo/chromo shadow domain	PROSITE	PS50013	CHROMO_2	coord: 65..124 score: 16.178
IPR002110	Ankyrin repeat	SMART	SM00248	ANK_2a	coord: 463..492 e-value: 4.1 score: 16.4 coord: 429..460 e-value: 0.0085 score: 25.3 coord: 495..524 e-value: 0.0095 score: 25.1
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 495..521 score: 9.458
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 429..461 score: 11.22
IPR036770	Ankyrin repeat-containing domain superfamily	GENE3D	G3DSA:1.25.40.20		coord: 407..573 e-value: 3.6E-20 score: 74.5
IPR036770	Ankyrin repeat-containing domain superfamily	SUPERFAMILY	SSF48403	Ankyrin repeat	coord: 382..523
IPR023780	Chromo domain	PFAM	PF00385	Chromo	coord: 65..115 e-value: 4.7E-14 score: 52.0
None	No IPR available	GENE3D	G3DSA:2.40.50.40		coord: 36..120 e-value: 3.3E-19 score: 70.5
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..23
None	No IPR available	PANTHER	PTHR24178	FAMILY NOT NAMED	coord: 432..521
None	No IPR available	PANTHER	PTHR24178:SF9	ANKYRIN REPEAT AND SOCS BOX PROTEIN 3	coord: 432..521
None	No IPR available	CDD	cd00024	CD_CSD	coord: 65..113 e-value: 6.94656E-20 score: 81.3692
IPR020683	Ankyrin repeat-containing domain	PFAM	PF12796	Ank_2	coord: 434..520 e-value: 1.7E-12 score: 47.7
IPR020683	Ankyrin repeat-containing domain	PROSITE	PS50297	ANK_REP_REGION	coord: 429..521 score: 18.749
IPR016197	Chromo-like domain superfamily	SUPERFAMILY	SSF54160	Chromo domain-like	coord: 59..118

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Chromobox protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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