SMED30004285

Overview
NameSMED30004285
Smed IDSMED30004285
Length (bp)1029
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30004285 (SMED30004285) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30004285 (SMED30004285) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30004285 (SMED30004285) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30004285 (SMED30004285) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30004285

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30004285h1SMcG0019876 dd_Smed_v4_15802_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30004285h1SMcG0019876 dd_Smed_v4_15802_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30004285 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.010211:291..3050 +5123
Homology
BLAST of SMED30004285 vs. TrEMBL
Match: S5WMZ9 (Sh3bp2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 93.5893 bits (231), Expect = 5.898e-18
Identity = 85/314 (27.07%), Postives = 151/314 (48.09%), Query Frame = 1
Query:  133 PAEMLLNENKDICFIGNF-YQKISRFWIKQWLKRLVIISKGTIYTYPNSKSKLP---TMMAHLNISCSIEIVKKFTLFVCVLKS-DSSNPLSSIKFGAKSRSKLDELVRAVEESMKFNEQEIHLVGVSQRNSNSTSGYLSIP---------LPEISKSLTSSTMLKNEFCSDNN--VIYINEKNT---PKNDNRCSFTIYYDYSELCDP--------QLNLENIIFKGTSDEASKELFRSFHLGAFLIRLREDVKILTVQCPECIIKYVLEVDPESNRVNIKGESVTFDNIMDLLAYYHKFCLPRQNCKLTTPY 993
            PA+ LL +  +I F G     K S+  + +W+K  VI+ +G IY Y N  S+ P    +++  N    ++  KK  L+V +L+  D++N  S + F A S  ++  ++   +E M  ++ ++    V+  N      Y  I          LP I K +  +  L       NN  ++  + +N+   P   N  + T+  D  +   P        ++ + + IF GT +EA+  L +   +G +LIR++ D ++L+VQ    I+KY L  +P + RV+I+G    F N+ DL+ +Y+   +P   C+L  PY
Sbjct:    5 PAQSLLRK-PNITFSGILETSKTSKMSLHKWVKCYVIVFEGNIYIYENCLSESPKSTNVLSKFNEFHVLKNRKKSPLWVFILQPIDNAN--SQLSFAAPSEQEMLYVIGKFKEGMMHSQSQLSAPNVNFTNPEIYPPYPIINNANLNFQSNLPPIPKGIHPNERLMENCIETNNEKILKFDNRNSVCAPPYPNINALTL--DRRDDLPPIPSESHSEEICMRDFIFNGTREEAAAVLSKVQQIGGYLIRVQGDRQVLSVQTERGIVKYKLYKNPLTERVSIQGFGNEFYNLTDLVKHYYTNNIPNYTCRLKCPY 313          
BLAST of SMED30004285 vs. Planmine SMEST
Match: SMESG000072376.1 (SMESG000072376.1)

HSP 1 Score: 611.683 bits (1576), Expect = 0.000e+0
Identity = 299/299 (100.00%), Postives = 299/299 (100.00%), Query Frame = 1
Query:  115 MSLKVVPAEMLLNENKDICFIGNFYQKISRFWIKQWLKRLVIISKGTIYTYPNSKSKLPTMMAHLNISCSIEIVKKFTLFVCVLKSDSSNPLSSIKFGAKSRSKLDELVRAVEESMKFNEQEIHLVGVSQRNSNSTSGYLSIPLPEISKSLTSSTMLKNEFCSDNNVIYINEKNTPKNDNRCSFTIYYDYSELCDPQLNLENIIFKGTSDEASKELFRSFHLGAFLIRLREDVKILTVQCPECIIKYVLEVDPESNRVNIKGESVTFDNIMDLLAYYHKFCLPRQNCKLTTPYKLCCID 1011
            MSLKVVPAEMLLNENKDICFIGNFYQKISRFWIKQWLKRLVIISKGTIYTYPNSKSKLPTMMAHLNISCSIEIVKKFTLFVCVLKSDSSNPLSSIKFGAKSRSKLDELVRAVEESMKFNEQEIHLVGVSQRNSNSTSGYLSIPLPEISKSLTSSTMLKNEFCSDNNVIYINEKNTPKNDNRCSFTIYYDYSELCDPQLNLENIIFKGTSDEASKELFRSFHLGAFLIRLREDVKILTVQCPECIIKYVLEVDPESNRVNIKGESVTFDNIMDLLAYYHKFCLPRQNCKLTTPYKLCCID
Sbjct:    1 MSLKVVPAEMLLNENKDICFIGNFYQKISRFWIKQWLKRLVIISKGTIYTYPNSKSKLPTMMAHLNISCSIEIVKKFTLFVCVLKSDSSNPLSSIKFGAKSRSKLDELVRAVEESMKFNEQEIHLVGVSQRNSNSTSGYLSIPLPEISKSLTSSTMLKNEFCSDNNVIYINEKNTPKNDNRCSFTIYYDYSELCDPQLNLENIIFKGTSDEASKELFRSFHLGAFLIRLREDVKILTVQCPECIIKYVLEVDPESNRVNIKGESVTFDNIMDLLAYYHKFCLPRQNCKLTTPYKLCCID 299          
BLAST of SMED30004285 vs. Planmine SMEST
Match: SMESG000072391.1 (SMESG000072391.1)

HSP 1 Score: 129.028 bits (323), Expect = 1.251e-34
Identity = 97/325 (29.85%), Postives = 154/325 (47.38%), Query Frame = 1
Query:  115 MSLKVVPAEMLLNENKDICFIGNFYQKISRFWIKQWLKRLVIISKGTIYTYPNSKSKLPTMMAHLNISCSIEIV----KKFTLFVCVLKSDSSNPLSSIKFGAKSRSKLDELVRAVEESMK------FNEQEIHLVGVSQRNSNSTSGY----------LSIP----------LPEISKSLTSSTMLKNEFCSDNNVIYINEKNTPKNDNRCSFTIYYDYSELCDPQLNLENIIFKGTSDEASKELFRSFHLGAFLIRLREDVKILTVQCPECIIKYVLEVDPESNRVNIKGESVTFDNIMDLLAYYHKFCLPRQNCKLTTPYKL 999
            M+LK V A+ L   ++   F G+ + K+S    K W+K   I+ KG+ Y Y N  +K P M+  L  S  +EI      ++ L   V  + + N +  +KFG  S+  L  L+++  ES+       F   E +   +S    NS + +            +P          +P+   S TSS           N IY++  +   N                   +NL+++IFKGTS EA +EL ++   GA+L+R   + K LTVQ  + ++KYVL  +  +N V I+ + + F+++ DLLAYYHK  +P + CKL  PYKL
Sbjct:    1 MTLKSVDAQTLRATDEK-RFAGDLFHKVSHLGSKTWVKVYTILFKGSFYVYSNVDAKQPKMVVILTASSKVEITSNRKNRYMLSFTVFSNSNDNSIRQLKFGTYSQEILSTLMKSFNESINRGANNYFTSNEPNDFKMSLNRVNSNTHFENNVNEELFIYDMPERPVIGFKNGMPDFDLSETSSQ----------NSIYLSIDSETYN-------------------INLDDVIFKGTSYEAYQELEKNVCYGAYLVREENNAKRLTVQTRDEVLKYVLITNTNNNFVQIQNQEMKFNSLQDLLAYYHKNDIPGRKCKLVIPYKL 295          
BLAST of SMED30004285 vs. Planmine SMEST
Match: SMESG000072396.1 (SMESG000072396.1)

HSP 1 Score: 125.946 bits (315), Expect = 1.891e-33
Identity = 93/303 (30.69%), Postives = 155/303 (51.16%), Query Frame = 1
Query:  130 VPAEMLLNENKDICFIGNFYQKISRFWIKQWLKRLVIISKGTIYTYPNSKSKLPTMMAHLNISCSIEIVKK-----FTLFVCVLKSDSSNPLSSIKFGAKSRSKLD------ELVRAVEESMKFNEQEIHLVGVSQRNSNSTSGYLSIP-LPEISKSLTSSTMLKNEFCSDNNVIYINEKNTPKNDNRCSFTIYYDYSELCD-PQLNLENIIFKGTSDEASKELFRSFHLGAFLIRLREDVKILTVQCPECIIKYVLEVDPESNRVNIKGESVTFDNIMDLLAYYHKFCLPRQNCKLTTPYKL 999
            +PA++LL ++  + F G   +KI+    K W+K  V+IS G IY Y +S S  P ++  L     I+I+K      F +F      DS   +  +KF A S  +++      +L   + ++ +  +    +   S +N+   S Y ++    EI  +L  S  +      D+ +  IN  N        + T + + S   D    N+E +IF GT +EA  EL +  +LG++L+R     +ILTV+C   I+KY L  DP+++R++I G+  +F+N+  LL+YYH+  LP QNCKL  P+K 
Sbjct:   10 LPAQILL-QDSSVTFSGYLERKITMLSFKHWIKCYVVISNGNIYIYSSSTSPKPVLVCILGAFHQIQIIKNRIQPPFWVFTLKPLIDS---VPELKFAAASEREMNFWISEFKLGIILSKNTQLKDDSERISSQSCKNNMEGSIYSTVSERNEIVDTLLHSDKINIYEEPDDLIFQINPVNPTAPPLYPTLTQFDNLSLKSDTSDENVEYVIFYGTREEAFSELLKRPYLGSYLVRQDNGRQILTVKCESNIVKYCLLSDPKTDRIHIAGQKESFENVYHLLSYYHEHYLPNQNCKLLIPFKF 308          
BLAST of SMED30004285 vs. Planmine SMEST
Match: SMESG000072368.1 (SMESG000072368.1)

HSP 1 Score: 115.931 bits (289), Expect = 1.065e-29
Identity = 95/310 (30.65%), Postives = 152/310 (49.03%), Query Frame = 1
Query:  172 FIGNFYQKISRFWIKQWLKRLVIISKGTIYTYPNSKSKLPTMMAHLNISCSIEIV---KKFTLFVCVLKSDS-SNPLSSIKFGAKSRSKLDELVRAVEESMKFNEQE-----------IHLVGVSQRNSNSTSGYLSIPL----PEISKSLTSSTMLKN------------EFCSDNNVIYINEKNTPKNDNRC---SFTIYYDYSELCDPQLNLENIIFKGTSDEASKELFRSFHLGAFLIRLREDVKILTVQCPECIIKYVLEVDPESNRVNIKGESVTFDNIMDLLAYYHKFCLPRQNCKLTTPYKL 999
            + G  +Q+I     K+W+K  + + KG+IY Y + K+  P M+A L    +IEI+   KK  L V  +  +S  N +  + FG  +  +++ +V+  E ++  ++Q            I       RNS     +  +P     P+   +  SS    N            E CS + + +I+E NTP  DN       +IY D     D  +NL++II +GTS EA +EL  +   GA+L+R  +  KILTVQC   ++KY L     +N + IK  ++ F+++ +LL YY K  +P + CKL  PYKL
Sbjct:    4 YSGYLFQQILNSGKKKWIKVFIKLHKGSIYIYSDDKAIKPKMVAILAGYSTIEILTGRKKHPLHVISICPNSPRNSVVPLVFGTTTEPEMEFIVKLFESNISKSKQNFFFNKSTGENIISNNKTGSRNSFEKESHSELPQHNYNPDYYSNYNSSDESSNYDVAEETFKENSEGCSFDEIYFISE-NTPLQDNETVDNDLSIYVD-----DCPINLDHIILEGTSIEAYQELKNNICHGAYLVRQDKGRKILTVQCANEVLKYELITHQNNNCIQIKNNNIVFNSLQNLLNYYQKNDIPGRQCKLVIPYKL 307          
BLAST of SMED30004285 vs. Planmine SMEST
Match: SMESG000006092.1 (SMESG000006092.1)

HSP 1 Score: 102.064 bits (253), Expect = 1.708e-24
Identity = 87/310 (28.06%), Postives = 147/310 (47.42%), Query Frame = 1
Query:  133 PAEMLLNENKDICFIGNFYQKISRFWIKQWLKRLVIISKGTIYTYPNSKSKLPTMMAHLNISCSIEIVK---KFTLFVCVLKSDSSNPLSSIKFGAKSRSKLDELVRAVEESMKFNEQEIHLVGVSQRNS---------NSTSGYLSIPLPEISKSLTSSTMLKNEFCSDNN--VIYINEKNT---PKNDNRCSFTIYYDY------SELCDPQLNLENIIFKGTSDEASKELFRSFHLGAFLIRLREDVKILTVQCPECIIKYVLEVDPESNRVNIKGESVTFDNIMDLLAYYHKFCLPRQNCKLTTPY 993
            PA+ LL +  +I F G    KIS+     W++  VI+ +G IY Y N  S+ P     L+      ++K   K  L+V +L+    N  S + F A S  ++  ++   +E M  ++  +    V+  N          NS +      LP I K +  +  L       NN  V+ I+ +N+   P   N  + T+          SE    ++ + + IF GT +EA+  L +   +G +LIR++ D ++L+VQ    I+KYVL+ +P + RV+I+G    F N+ DL+ +Y+   +P   C+L  PY
Sbjct:    8 PAQSLLRK-PNITFSGILENKISKMSFHIWVRCYVIVFEGNIYIYENCFSESPKSTNVLSKFKEFHVLKNRKKSPLWVFILQP-IDNETSQLSFAAPSEQEMLYVIGKFKEGMMHSQSHLSAPNVNFTNPGIYPPYPIINSATLNFQSNLPPIPKGIHPNERLMENCIETNNKKVLTIDNRNSVCAPLYPNINALTLERRNDLPPIPSESHSEEICMRDFIFNGTREEAAAVLSKVQQIGGYLIRVQGDRQVLSVQTERGIVKYVLDKNPLTERVSIQGSGNEFYNLTDLVKHYYTNNIPNYTCRLKCPY 315          
The following BLAST results are available for this feature:
BLAST of SMED30004285 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 1
Match NameE-valueIdentityDescription
S5WMZ95.898e-1827.07Sh3bp2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=... [more]
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BLAST of SMED30004285 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30004285 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000072376.10.000e+0100.00SMESG000072376.1[more]
SMESG000072391.11.251e-3429.85SMESG000072391.1[more]
SMESG000072396.11.891e-3330.69SMESG000072396.1[more]
SMESG000072368.11.065e-2930.65SMESG000072368.1[more]
SMESG000006092.11.708e-2428.06SMESG000006092.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004285 ID=SMED30004285|Name=SMED30004285|organism=Schmidtea mediterranea sexual|type=transcript|length=1029bp
AACATTATAAACAAAAATAAATACACTCATATTTAATATCAAACCTTAAT
TGAAATCATTTCAATTGTTAATCATTGAAAAATTACTGGTAATCAAAAGG
TTTAATTGAATTGAATGAGTTTAAAAGTGGTACCCGCCGAAATGCTTCTG
AATGAGAATAAAGATATTTGTTTTATTGGAAATTTCTATCAAAAGATTTC
TCGATTTTGGATCAAACAATGGCTGAAACGCTTAGTTATTATATCAAAAG
GAACTATCTACACATATCCTAATAGTAAGTCTAAACTTCCTACTATGATG
GCGCATCTCAACATATCTTGTTCAATTGAAATTGTAAAGAAATTTACATT
ATTCGTTTGTGTCTTGAAGTCGGATTCAAGTAACCCTTTGTCTTCAATAA
AATTCGGAGCCAAATCAAGGTCAAAGTTAGACGAATTAGTGAGAGCGGTG
GAAGAAAGTATGAAATTCAATGAACAGGAGATCCACCTGGTAGGTGTCTC
TCAAAGAAATTCAAATTCAACAAGCGGCTATCTTTCGATACCTCTTCCTG
AAATATCAAAGTCATTAACTTCATCAACCATGTTGAAGAACGAATTCTGT
TCTGACAATAATGTAATTTATATTAATGAAAAGAATACACCAAAGAATGA
TAATCGATGCTCTTTCACTATTTATTATGATTATAGTGAATTGTGTGACC
CACAACTGAATTTGGAAAACATTATTTTTAAGGGAACCAGTGATGAAGCA
AGTAAGGAACTTTTCAGGTCATTTCATCTGGGAGCATTCTTGATTCGTTT
AAGGGAAGATGTGAAGATATTAACTGTTCAGTGCCCAGAATGTATAATAA
AATATGTTTTAGAAGTCGATCCAGAAAGCAATAGAGTCAATATTAAAGGA
GAAAGTGTAACTTTTGACAATATCATGGATTTATTAGCATATTATCACAA
ATTCTGTCTTCCTAGGCAAAATTGCAAATTAACAACACCTTATAAATTGT
GCTGTATTGATTAATAATATAAACAGAAC
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protein sequence of SMED30004285-orf-1

>SMED30004285-orf-1 ID=SMED30004285-orf-1|Name=SMED30004285-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=300bp
MSLKVVPAEMLLNENKDICFIGNFYQKISRFWIKQWLKRLVIISKGTIYT
YPNSKSKLPTMMAHLNISCSIEIVKKFTLFVCVLKSDSSNPLSSIKFGAK
SRSKLDELVRAVEESMKFNEQEIHLVGVSQRNSNSTSGYLSIPLPEISKS
LTSSTMLKNEFCSDNNVIYINEKNTPKNDNRCSFTIYYDYSELCDPQLNL
ENIIFKGTSDEASKELFRSFHLGAFLIRLREDVKILTVQCPECIIKYVLE
VDPESNRVNIKGESVTFDNIMDLLAYYHKFCLPRQNCKLTTPYKLCCID*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
Vocabulary: INTERPRO
TermDefinition
IPR036860SH2_dom_sf
IPR035848SH3BP2
IPR000980SH2
IPR011993PH-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
Vocabulary: molecular function
TermDefinition
GO:0005070SH3/SH2 adaptor activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR036860SH2 domain superfamilyGENE3DG3DSA:3.30.505.10coord: 195..296
e-value: 2.1E-6
score: 29.2
IPR036860SH2 domain superfamilySUPERFAMILYSSF55550SH2 domaincoord: 205..293
IPR035848SH3 domain-binding protein 2PANTHERPTHR15126SH3-BINDINGcoord: 201..294
NoneNo IPR availableCDDcd00173SH2coord: 208..277
e-value: 5.18979E-5
score: 38.9759
NoneNo IPR availableSUPERFAMILYSSF50729PH domain-likecoord: 27..111