Innexin

Overview


Name	Innexin
Smed ID	SMED30004277
Length (bp)	2403

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Innexin (SMED30004277) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30004277) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30004277) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30004277) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30004277

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
neoblast	SMED30004277	SMESG000055258.1	AY067503	smed_ncbi_20200123	PMID:17670787 Oviedo et al., 2007
parenchyma	SMED30004277	SMESG000055258.1	AY067503	smed_ncbi_20200123	PMID:17670787 Oviedo et al., 2007
pigment cell	SMED30004277	SMESG000055258.1 SMESG000024134.1	SmedASXL_015009	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
epidermis	SMED30004277	SMESG000055258.1 SMESG000055257.1	SmedASXL_015008	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
pigment cell	SMED30004277	SMESG000055258.1 SMESG000055257.1	SmedASXL_015008	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
gut	SMED30004277	SMESG000055258.1 SMESG000055257.1	dd_Smed_v4_3659_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30004277	SMESG000055258.1 SMESG000055257.1	dd_Smed_v4_3659_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30004277	SMESG000055258.1 SMESG000055257.1	dd_Smed_v4_3659_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30004277	SMESG000055258.1 SMESG000055257.1	Contig42024	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30004277	SMESG000055258.1 SMESG000055257.1	Contig42024	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
pigment cell	SMED30004277	SMESG000055258.1 SMESG000055257.1	dd_Smed_v6_3659_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 222.631 bits (566), Expect = 3.856e-65
Identity = 131/374 (35.03%), Postives = 208/374 (55.61%), Query Frame = 2

Query:  314 RLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY-LNFDKEFK---SGSQFQTINYIQWISIVLAVQGILFFIPCMIWR-LLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLN-KKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELL----DLYRSQEKDEYEPLN 1405
            R+ DDF DKLNY ++  +I    I+++  QY   PIQCW P +FT +WE+Y  ++C + +TY L     F       + + I+Y QW+  VLA++ + F+IPC++WR LL  HSG N+Q + Q A +  +   D    +++ IA HM+  L  ++   + +  C +KR  +     Y++ +Y+ IK+LYL NVV Q+ M+  ++GT   FYG     D++ G E   S   P+V +C FE+  L     +T+QCVL +NMF EKIF+ LWFW  ++  ++AVS+  W+         ++FI     L      ++   VKKF+  +L  DG+F M +IS + GDI+A +++  L     D  R  + +  E LN
Sbjct:   16 RVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREVTDVSGMCVQKRWAN-----YVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFI--RKYLRATDLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFNDRVRKIQFNSTESLN 382

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Query:  314 RLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY-LNFDKEFK---SGSQFQTINYIQWISIVLAVQGILFFIPCMIWR-LLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLN-KKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELL----DLYRSQEKDEYEPLN 1405
            R+ DDF DKLNY ++  +I    I+++  QY   PIQCW P +FT +WE+Y  ++C + +TY L     F       + + I+Y QW+  VLA++ + F+IPC++WR LL  HSG N+Q + Q A +  +   D    +++ IA HM+  L  ++   + +  C +KR  +     Y++ +Y+ IK+LYL NVV Q+ M+  ++GT   FYG     D++ G E   S   P+V +C FE+  L     +T+QCVL +NMF EKIF+ LWFW  ++  ++AVS+  W+         ++FI     L      ++   VKKF+  +L  DG+F M +IS + GDI+A +++  L     D  R  + +  E LN
Sbjct:   16 RVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREVTDVSGMCVQKRWAN-----YVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFI--RKYLRATDLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFNDRVRKIQFNSTESLN 382

[Close]

BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 222.631 bits (566), Expect = 1.409e-64
Identity = 126/354 (35.59%), Postives = 201/354 (56.78%), Query Frame = 2

Query:  314 RLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY-LNFDKEFK---SGSQFQTINYIQWISIVLAVQGILFFIPCMIWR-LLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLN-KKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGEL 1357
            R+ DDF DKLNY ++  +I    I+++  QY   PIQCW P +FT +WE+Y  ++C + +TY L     F       + + I+Y QW+  VLA++ + F+IPC++WR LL  HSG N+Q + Q A +  +   D    +++ IA HM+  L  ++   + +  C +KR  +     Y++ +Y+ IK+LYL NVV Q+ M+  ++GT   FYG     D++ G E   S   P+V +C FE+  L     +T+QCVL +NMF EKIF+ LWFW  ++  ++AVS+  W+         ++FI     L      ++   VKKF+  +L  DG+F M +IS + GDI+A +++  L
Sbjct:   16 RVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREVTDVSGMCVQKRWAN-----YVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFI--RKYLRATDLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVAL 362

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BLAST of Innexin vs. Ensembl Celegans
Match: inx-13 (Innexin [Source:UniProtKB/TrEMBL;Acc:O44887])

HSP 1 Score: 210.305 bits (534), Expect = 1.291e-60
Identity = 115/372 (30.91%), Postives = 204/372 (54.84%), Query Frame = 2

Query:  323 DDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQ----TINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKS-CSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLV---NRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLY------RSQEKDEYE 1396
            DD  D+LNY ++ +L+++  + ++  QY  +PIQCW P +FT +WE+Y+ ++C + +TY     ++   S+       I Y QW+  +L +Q ILF++P + WRL+  +SG  L++++  A            ++ K    H+       Y + T +S  +K          YL+ +Y+ +K LYL+ +VFQ  ++  ++GT Y+F+G+    D++ G E   S + P+V +C FE+  L  +  +T+QCVL +NMF EK+++ LWFW VI+G  T ++L++W  KL+    RK  ++   +              ++ KF+   L++DG+FI HLI  N G + + D++ ++ D +      RSQ+K   E
Sbjct:   17 DDSIDRLNYYWTPMLLVIFALTLSAKQYVGQPIQCWIPAQFTGAWEQYSENYCFVQNTYFISPDKYIPDSEIDREGAEIGYYQWVPFILGLQAILFYLPSLFWRLMNFNSGVALKKMLFGAKKADRVDEKARNEAAKSTGAHL-------YESLTLQSRFAKYTSAFTYGGSYLTYLYLFVKFLYLVQIVFQFIILNNFLGTSYTFWGLGILSDILNGREWEESGHFPRVTMCDFEVRVLGNKHRHTVQCVLMINMFNEKVYVFLWFWLVIVGVATFLNLVNWTRKLMFRSARKAHIKSYLQIEDNFSDDNSRNGQILDKFVDYKLKSDGVFITHLIDNNGGSVFSHDVIVDMWDRFLQDEDNRSQKKQPAE 381

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BLAST of Innexin vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393])

HSP 1 Score: 209.534 bits (532), Expect = 2.833e-60
Identity = 114/366 (31.15%), Postives = 212/366 (57.92%), Query Frame = 2

Query:  290 GKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL----NFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRC--CSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLY 1369
              ++S +  + DD  DKLNY ++  +I V  IL++  QY   PIQCW P  FT+  E+Y  ++C + +TY     ++     +  + + I Y QW+  VLA++ +LF++P ++WRLL   SG ++Q ++Q A ++ +   +   ++++ IA ++++ L+ K+   +           C+++S   ++ +YI +KILY +N+V Q+ ++  ++G R  +YG+    D++ G E   S + P+V LC FE+  L     +T+QCVL +NMF EKIF+ LWFW  ++   T  SL  W+   V    ++ F+G+YL  +E  K  +   +++F+F +LR DG+F++ +++T+ G++   ++   L + Y
Sbjct:   10 SAVKSIQFHVDDDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375

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BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860)

HSP 1 Score: 66.6254 bits (161), Expect = 3.317e-11
Identity = 71/299 (23.75%), Postives = 124/299 (41.47%), Query Frame = 2

Query:  320 IDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQC--------------WTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYL-------PKVKLCKF-EITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLL 1150
            ID+   +++YK + I++I   +L+   QY   PI C              W    FT    E      G            +   + +   Y QW+  VL  Q ILF++P  +W+      G  L+ ++   N+  V+  D+ K   K I +  D F+                  + N   + +  + + + L  +NV+ Q+  +  ++   +S YG     D++K  EL   + +       PKV  C F +         +   CVLPLN+  EKI++ LWFW +I+  ++ +SL+
Sbjct:   19 IDNNVFRMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTYCWIYSTFTVP--ERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSW---EGGRLKMLVMDLNSPIVN--DECKNDRKKILV--DYFIG-----------------NLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYG----SDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI 287

[Close]

BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005)

HSP 1 Score: 66.6254 bits (161), Expect = 3.317e-11
Identity = 71/299 (23.75%), Postives = 124/299 (41.47%), Query Frame = 2

Query:  320 IDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQC--------------WTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYL-------PKVKLCKF-EITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLL 1150
            ID+   +++YK + I++I   +L+   QY   PI C              W    FT    E      G            +   + +   Y QW+  VL  Q ILF++P  +W+      G  L+ ++   N+  V+  D+ K   K I +  D F+                  + N   + +  + + + L  +NV+ Q+  +  ++   +S YG     D++K  EL   + +       PKV  C F +         +   CVLPLN+  EKI++ LWFW +I+  ++ +SL+
Sbjct:   19 IDNNVFRMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTYCWIYSTFTVP--ERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSW---EGGRLKMLVMDLNSPIVN--DECKNDRKKILV--DYFIG-----------------NLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYG----SDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI 287

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BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0332314)

HSP 1 Score: 66.6254 bits (161), Expect = 3.317e-11
Identity = 71/299 (23.75%), Postives = 124/299 (41.47%), Query Frame = 2

Query:  320 IDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQC--------------WTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYL-------PKVKLCKF-EITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLL 1150
            ID+   +++YK + I++I   +L+   QY   PI C              W    FT    E      G            +   + +   Y QW+  VL  Q ILF++P  +W+      G  L+ ++   N+  V+  D+ K   K I +  D F+                  + N   + +  + + + L  +NV+ Q+  +  ++   +S YG     D++K  EL   + +       PKV  C F +         +   CVLPLN+  EKI++ LWFW +I+  ++ +SL+
Sbjct:   19 IDNNVFRMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTYCWIYSTFTVP--ERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSW---EGGRLKMLVMDLNSPIVN--DECKNDRKKILV--DYFIG-----------------NLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYG----SDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI 287

[Close]

BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071006)

HSP 1 Score: 66.6254 bits (161), Expect = 3.317e-11
Identity = 71/299 (23.75%), Postives = 124/299 (41.47%), Query Frame = 2

Query:  320 IDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQC--------------WTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYL-------PKVKLCKF-EITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLL 1150
            ID+   +++YK + I++I   +L+   QY   PI C              W    FT    E      G            +   + +   Y QW+  VL  Q ILF++P  +W+      G  L+ ++   N+  V+  D+ K   K I +  D F+                  + N   + +  + + + L  +NV+ Q+  +  ++   +S YG     D++K  EL   + +       PKV  C F +         +   CVLPLN+  EKI++ LWFW +I+  ++ +SL+
Sbjct:   19 IDNNVFRMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTYCWIYSTFTVP--ERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSW---EGGRLKMLVMDLNSPIVN--DECKNDRKKILV--DYFIG-----------------NLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYG----SDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI 287

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BLAST of Innexin vs. Ensembl Fly
Match: Inx3 (gene:FBgn0265274 transcript:FBtr0085350)

HSP 1 Score: 65.4698 bits (158), Expect = 7.835e-11
Identity = 57/250 (22.80%), Postives = 109/250 (43.60%), Query Frame = 2

Query:  425 CWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQ----RIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDA--FYDMVKGNELRSS-DYLPKVKLCKF-EITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLL 1150
            CW    +T   +++ +    ++   L    E+    ++ +  Y QW+  VL  QG++F++P  +W+        N++    R++       VS PD  ++  +     +  F+N                 S N+    S  Y   ++L  +NV+  + M+ +++G  +  YG D   F +M +        +  P++  C F +         +   CVL LN+  EKI+I LWFW +I+  I+ V++L
Sbjct:   75 CWITYTYTIPGQQHRQIGTDVAGPGLG--NEYGQEKRYHS--YYQWVPFVLFFQGLMFYVPHWVWK--------NMEDGKIRMITDGLRGMVSVPDDYRRDRQDRI--LKYFVN-----------------SLNTHNGYSFAYFFCELLNFINVIVNIFMVDKFLGGAFMSYGTDVLKFSNMDQDKRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAVL 293

[Close]

BLAST of Innexin vs. Ensembl Zebrafish
Match: CR749164.1 (pep chromosome:GRCz11:21:30355767:30361679:1 gene:ENSDARG00000116832.1 transcript:ENSDART00000189948.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR749164.1)

HSP 1 Score: 65.4698 bits (158), Expect = 2.892e-10
Identity = 38/108 (35.19%), Postives = 55/108 (50.93%), Query Frame = 1

Query: 2044 PVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            P R ++ PLS  + + ++    E L +G I  S S  S+  + V  KDG+ RPC DYR LN IT+   Y   LV     +L  A  F  +DL  A + + +R+ D  K
Sbjct:  517 PPRGRIFPLSQPETEAMKKYISEELEKGFIRPSTSPASAGFFFVKKKDGSLRPCIDYRGLNEITVKYRYPLPLVPAALEQLRSAQYFTKLDLRSAYNLIRIRQGDEWK 624

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BLAST of Innexin vs. Ensembl Zebrafish
Match: BX546500.1 (pep chromosome:GRCz11:23:12926092:12931693:-1 gene:ENSDARG00000086495.3 transcript:ENSDART00000122176.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX546500.1)

HSP 1 Score: 63.5438 bits (153), Expect = 1.051e-9
Identity = 38/108 (35.19%), Postives = 54/108 (50.00%), Query Frame = 1

Query: 2044 PVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            P + K+  LS  + + +     + L   II  S S   +  + V  KDG+ RPC DYR LN IT+ ++Y   L++  F RL  A  F  +DL  A H V +R  D  K
Sbjct:  498 PPKGKLYSLSVPEREAMEKYISDSLAAKIIRPSSSPAGAGFFFVKKKDGSLRPCIDYRGLNSITVKNTYPLPLMSSAFERLQGANFFTKLDLRNAYHLVRIRPGDEWK 605

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BLAST of Innexin vs. Ensembl Zebrafish
Match: BX511224.1 (pep chromosome:GRCz11:2:18017000:18022765:1 gene:ENSDARG00000113243.1 transcript:ENSDART00000186877.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX511224.1)

HSP 1 Score: 63.5438 bits (153), Expect = 1.074e-9
Identity = 38/108 (35.19%), Postives = 54/108 (50.00%), Query Frame = 1

Query: 2044 PVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            P + K+  LS  + + +     + L   II  S S   +  + V  KDG+ RPC DYR LN IT+ ++Y   L++  F RL  A  F  +DL  A H V +R  D  K
Sbjct:  524 PPKGKLYSLSVPEREAMEKYISDSLAAKIIRPSSSPAGAGFFFVKKKDGSLRPCIDYRGLNSITVKNTYPLPLMSSAFERLQGANFFTKLDLRNAYHLVCIRPGDEWK 631

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BLAST of Innexin vs. Ensembl Zebrafish
Match: CR855320.1 (pep chromosome:GRCz11:1:7956030:7961696:1 gene:ENSDARG00000099359.2 transcript:ENSDART00000159655.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR855320.1)

HSP 1 Score: 63.5438 bits (153), Expect = 1.112e-9
Identity = 38/108 (35.19%), Postives = 54/108 (50.00%), Query Frame = 1

Query: 2044 PVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            P + K+  LS  + + +     + L   II  S S   +  + V  KDG+ RPC DYR LN IT+ ++Y   L++  F RL  A  F  +DL  A H V +R  D  K
Sbjct:  526 PPKGKLYSLSAPEREAMGKYISDSLAAKIIRPSSSPAGAGFFFVKKKDGSLRPCIDYRGLNNITVKNTYPLPLMSSAFERLQGANFFTKLDLRNAYHLVRIRAGDEWK 633

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BLAST of Innexin vs. Ensembl Zebrafish
Match: BX511082.1 (pep chromosome:GRCz11:9:14291932:14297132:1 gene:ENSDARG00000113678.1 transcript:ENSDART00000183119.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX511082.1)

HSP 1 Score: 62.7734 bits (151), Expect = 1.484e-9
Identity = 37/105 (35.24%), Postives = 55/105 (52.38%), Query Frame = 1

Query: 2044 PVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSD 2358
            P + K+  LS  + + +     + L   II  S S   +  + V  KDG+ RPC DYR LN IT+ ++Y   L++  F RL  A+ F  +DL  A H V +R+ D
Sbjct:  524 PPKGKLYSLSVPEREAMEKYISDSLAAKIIRPSSSPAGAGFFFVKKKDGSLRPCIDYRGLNAITVKNTYPLPLMSSAFERLQGASFFTKLDLRNAYHLVRIREGD 628

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BLAST of Innexin vs. Ensembl Xenopus
Match: anxa6 (annexin A6 [Source:Xenbase;Acc:XB-GENE-989741])

HSP 1 Score: 79.337 bits (194), Expect = 1.491e-14
Identity = 42/118 (35.59%), Postives = 66/118 (55.93%), Query Frame = 1

Query: 2014 NHFNETTTSLPVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
             H  +T T LP+R     ++      ++++  E+L  G+I  S S W+SP+ LVP KDG+ R C DYRRLN +T  D+Y    V+++  RL +A    T+DL +   Q+ +  S  +K
Sbjct:  327 EHKVDTGTQLPIRSPAYRVAEAVRPEMKSQIDEMLAFGVITPSHSPWASPVVLVPKKDGSTRFCVDYRRLNDVTTTDAYPMPRVDELLDRLGNAKYLTTLDLSRGYWQIPLAPSAQEK 444

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BLAST of Innexin vs. Ensembl Xenopus
Match: ENSXETT00000023941.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV463742.1:21:4282:-1 gene:ENSXETG00000015734.1 transcript:ENSXETT00000023941.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.2554 bits (186), Expect = 1.516e-13
Identity = 40/108 (37.04%), Postives = 62/108 (57.41%), Query Frame = 1

Query: 2017 HFNETTTSLPVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQV 2340
            H  +T T LP+R     ++      ++++  E+L  G+I  S S W+SP+ LVP KDG+ R C DYRRLN +T  D+Y    V+++  RL +A    T+DL +   Q+
Sbjct: 1061 HKVDTGTQLPIRSPAYRVAEAVRPEMKSQIDEMLAFGVITPSHSPWASPVVLVPKKDGSTRFCVDYRRLNDVTTTDAYPMPRVDELLDRLGNAKYLTTLDLSRGYWQI 1168

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BLAST of Innexin vs. Ensembl Xenopus
Match: vdac1 (voltage-dependent anion channel 1 [Source:Xenbase;Acc:XB-GENE-955063])

HSP 1 Score: 70.4774 bits (171), Expect = 7.033e-12
Identity = 38/110 (34.55%), Postives = 59/110 (53.64%), Query Frame = 1

Query: 2038 SLPVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            ++P R +  PLS  +   ++    E L +G I  S S   +  + V  KDG  RPC DYR LN IT+ + Y   L++++F +L  A IF  +DL  A + + +R+ D  K
Sbjct:  457 TMPPRGRTYPLSPAETAAMKEYISENLQRGFIRPSTSPAGAGFFFVEKKDGGLRPCIDYRGLNKITVKNRYPLPLISELFDQLKGAKIFSKLDLRGAYNLIRIREGDEWK 566

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BLAST of Innexin vs. Ensembl Xenopus
Match: ENSXETT00000003703.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:8:32912342:32914281:1 gene:ENSXETG00000000180.1 transcript:ENSXETT00000003703.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.4774 bits (171), Expect = 7.265e-12
Identity = 37/107 (34.58%), Postives = 58/107 (54.21%), Query Frame = 1

Query: 2038 SLPVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSD 2358
            ++P R +  PLS  +   ++    E L +G I  S S   +  + V  KDG  RPC DYR LN IT+ + Y   L++++F +L  A IF  +DL  A + + +R+ D
Sbjct:  407 TMPPRGRTYPLSPAETAAMKEYISENLQRGFIRPSTSPAGAGFFFVEKKDGGLRPCIDYRGLNKITVKNRYPLPLISELFDQLKGAKIFSKLDLRGAYNLIRIREGD 513

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BLAST of Innexin vs. Ensembl Xenopus
Match: alkbh5 (alkB homolog 5, RNA demethylase [Source:Xenbase;Acc:XB-GENE-987580])

HSP 1 Score: 70.0922 bits (170), Expect = 9.013e-12
Identity = 39/117 (33.33%), Postives = 61/117 (52.14%), Query Frame = 1

Query: 2023 NETTTSLPVRCKVRP--LSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            ++  T   V+  VRP  +   +   V  E   +L   +I  S S WSSP+ LVP  DG+ R C+D+R+LN ++  D+Y    V+++  RL  A    T+DL K   QV + +   +K
Sbjct:  226 HDIITGPGVKVNVRPYRIPEARRQAVAGEIKRMLELDVIEESHSEWSSPIVLVPKPDGSIRFCNDFRKLNEVSKFDAYPMPRVDELIERLGQARYITTLDLTKGYWQVPLTEGAKEK 342

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BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 209.534 bits (532), Expect = 3.604e-59
Identity = 114/366 (31.15%), Postives = 212/366 (57.92%), Query Frame = 2

Query:  290 GKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL----NFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRC--CSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLY 1369
              ++S +  + DD  DKLNY ++  +I V  IL++  QY   PIQCW P  FT+  E+Y  ++C + +TY     ++     +  + + I Y QW+  VLA++ +LF++P ++WRLL   SG ++Q ++Q A ++ +   +   ++++ IA ++++ L+ K+   +           C+++S   ++ +YI +KILY +N+V Q+ ++  ++G R  +YG+    D++ G E   S + P+V LC FE+  L     +T+QCVL +NMF EKIF+ LWFW  ++   T  SL  W+   V    ++ F+G+YL  +E  K  +   +++F+F +LR DG+F++ +++T+ G++   ++   L + Y
Sbjct:   10 SAVKSIQFHVDDDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375

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BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 191.43 bits (485), Expect = 2.573e-51
Identity = 114/360 (31.67%), Postives = 198/360 (55.00%), Query Frame = 2

Query:  314 RLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL-----NFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWR-LLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHM--DKFLNKKYNNETTKSCSKKRCCSQNSRR----YLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXX---XXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIV 1348
            RL DDF DKLNY ++  ++    +L++  QY   PIQCW P  FT + E+Y  ++C + +TY      +  +E  S    Q I Y QW+  +LA++ +LF++PC++WR LL  HSG NLQ ++Q A +  +   +   +++  +A HM  +  L        ++SC        N  R    Y++ +YI IK+LY  NV+ Q  ++   +G+    YG     D++   E   +   P+V LC FE+  L     +T+QCVL +NMF EKIF+ LWFW +  G +T  + + W+  +      + F+ +YL+++        +    ++KF  ++LR DG+F++ +IST+ G++++++++
Sbjct:  136 RLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQ-IGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELI 494

[Close]

BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23027|INX5_CAEEL (Innexin-5 OS=Caenorhabditis elegans OX=6239 GN=inx-5 PE=3 SV=2)

HSP 1 Score: 187.578 bits (475), Expect = 1.376e-50
Identity = 114/394 (28.93%), Postives = 196/394 (49.75%), Query Frame = 2

Query:  323 DDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQT------------INYIQWISIVLAVQGILFFIPCMIWRLLILHSGF---NLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXX---XXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLYRSQE------KDEYEPLNSVDEINLSE 1432
            +D +D+ +Y+++  L+    I++A +QY  +PIQCW P +FT++WE+YA  +C I  TY      F S  +               + Y QWI IVL +Q  LF++P +IWR            L  + +A+     +  D   K+ KF      ++  KK N        K+      S ++L ++Y+++KILYL N+V Q  ++  ++ T+   +G   F D++ G E  ++   P+V +C F I  L     +++QCV+ +NM  EK+++  WFW + +G +T  SL  W    + +     FI  YL+     +  +E    +   F+   L  DG+FI  L+  N GD+  + ++GE+  LYR++E      KD+   L +   ++L E
Sbjct:   19 NDIADRFSYQYTSTLLGFSAIMMAASQYVGRPIQCWVPAQFTRTWEKYAETYCFIKGTYF-LPGAFASEGEMSVTSPDDAVTATPQVGYYQWIPIVLVLQAFLFYLPSIIWRTFNESCELKIKELAAVSEASRKIKSNMSDDQVKATKF-----GRYFFKKLNFRNESPVFKETGSVVASGKFLPALYLLVKILYLANIVLQFWILTYFLETKSWMWGWQTFQDLMAGREWETTGIFPRVTMCDFSIMDLTSVHDHSIQCVIVINMLAEKVYVFFWFWLLFVGLLTVCSLAYWAVIYMLQSVGRNFIYSYLQQTPEFQTEQERGSFVPANFVDKCLTPDGVFISRLVQQNSGDLFTSIMLGEMFSLYRAREAEKAHKKDDDSALPASAPVDLQE 406

[Close]

BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23157|INX11_CAEEL (Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=inx-11 PE=3 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 3.099e-49
Identity = 121/385 (31.43%), Postives = 205/385 (53.25%), Query Frame = 2

Query:  287 IGKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY-------LNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQN---SRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGT-RYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXX------XXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLYRSQEKDE 1390
            +G  +    R  DD+SD+LNY  +  +++   +LI+  Q+  +PI+C  P +F  SWE+YA ++C   DTY       ++  K+ +  +  + ++Y QW+   L +Q   F  P  +W+    HSG  +  +++ A ++     +  +K+I  +  H+   L  + N E  K    K     N   S  ++S +Y+  K+LY LNV  QL ++  ++GT R+ +YG     D+V+G     S Y P+  +C FE+ ++     Y++QCVL +N+F EKIF+LLWFW VI+   + VSL+ W   LV       F+ ++L L  L          E+S V KF+  YL  DG+F++ ++S++ G I A D+V  L + Y  Q+K++
Sbjct:    8 LGMAKYLSPREDDDWSDRLNYLMTPNILLAFSVLISFKQFGGRPIECMFPNKFPGSWEQYAENYCWSQDTYFVEPTQDVSLLKKEERYTPDRQLSYYQWVPFFLLLQAAFFRAPSYLWKYFSNHSGIRIHEVVEKAKDSANVEEEVREKNILILKRHLSSALRFQANMERKKVQVHKTVTFLNFQYSSGFISWIYLFTKVLYFLNVFAQLYLMNYFLGTNRHHWYGFGVVQDIVQGEPWERSGYFPRAAVCDFEVRQVANIQRYSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLVFPCFSKWFVKQHLALSTLQNFNQRNSRREDSDVSKFVTQYLHKDGVFVLRMVSSHAGIIFATDLVQALYEAYDFQDKNK 392

[Close]

BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q27295|EAT5_CAEEL (Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN=eat-5 PE=2 SV=1)

HSP 1 Score: 177.178 bits (448), Expect = 3.950e-47
Identity = 105/374 (28.07%), Postives = 195/374 (52.14%), Query Frame = 2

Query:  308 KLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY---------LNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNE-TTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCIT-------------AVSLLSWLNKLVNRKDKVRFIGXXXXXXXX-XXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGEL 1357
            K RL D  +D+LNY +S ++I+ + + I   QY   P+QCW P +FTK+WE+YA D+C + +TY         L  ++        Q + Y QW   ++A++   F++P + W +L   SG N+ ++++ A     +  ++ KK I  I  H+   L K+ N E TTK    +R       +Y+++VY++ K++Y+ N   Q     +++G    ++G+    D++KG +   S   P++ +C F++  L     Y++QCVL LNMF EKIF+ L+ W +++  +T             +  L+ +L + ++ +D+     +  +  ++  KE    L+ +F       D + ++ +I+ + GDIV  +IVG +
Sbjct:   12 KPRLDDLGTDRLNYYYSTLIIMGMSLTITARQYVGSPLQCWVPAQFTKAWEQYAEDYCFVYNTYWVKPNDKVPLTVEERVS-----QQLIYYQWAPFIMAIEAAFFYLPVIFWSMLSTKSGINIIKLVETAQKAEGAESEERKKQIDIICRHISNNLRKRRNEEETTKMAKIQRIFGMQHGKYITNVYLVTKLIYMTNSFLQFYSTNKFLGQNDPYWGMRILDDILKGTDWEHSGNFPRIAMCDFQVRVLGNLQRYSIQCVLTLNMFNEKIFLFLYIWFLLVFFVTLFDSIFLCYNMFSSHKLVEFLQQFLDNQDQDENDEKKPEERKVYRKEQHSILLSEFCLHKFTPDIIILLKMINNHTGDIVCTEIVGRM 380

[Close]

BLAST of Innexin vs. TrEMBL
Match: Q2L6N1 (Innexin OS=Dugesia japonica OX=6161 GN=inx3 PE=2 SV=1)

HSP 1 Score: 316.62 bits (810), Expect = 1.291e-95
Identity = 179/441 (40.59%), Postives = 268/441 (60.77%), Query Frame = 2

Query:  260 EMDERPSWRI---GKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY---LNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSF-PDQLKKSIKFIAIHMDKFLNKK---YNNETTKSCSKKR--------------CCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLYRSQEKDEYEPLNSVD---EINLSENKLKNVEKIIGLEIPGKSYTNDN 1501
            +MD    WR+   G+I SNKLR  DDF D+LNY+F+ +L+ + I LI + QY  KPIQCW PQEFT+ WEEY  ++C +S+TY   +      K     Q I Y QW  I+L +Q +LF+IPC+IWR +   SGFN++RI+Q A++ + S  P+QL+KSI FIA HMD  L +    Y ++     + KR              C  +    +L+ +YI IK LYL+N++ QL +++++IGT+Y+FYGI   +D+++G+E   S   P+V  C  E  KL +   Y+LQCVLP+NMFLEKI+I LWFW+VI+G  T  SL SW+ ++ +  ++++ I  YL+LM +L ++++   +KF   YLR+DG F++ LI+ N+GD+VA D++ E+  +YR +   E+E L       E  L    L N   +   +  G S  N N
Sbjct:   38 DMDATFFWRLSKLGRIGSNKLRFDDDFVDRLNYQFTGLLLFMFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYTENYCWVSNTYFASIQNRMPSKDTRNEQMIGYYQWAPILLGLQSLLFYIPCLIWRNVSPQSGFNVRRILQVASDANCSLIPEQLQKSISFIARHMDTCLYRHRICYEHKHFMRSNGKRSKFSRCLAKLRCICCLGKLQGNFLTVLYISIKFLYLINIIGQLYLMEKFIGTKYTFYGIRVLWDLMRGHEWHHSGNFPRVTFCDLEAKKLGKNHLYSLQCVLPMNMFLEKIYIFLWFWHVIVGIATLCSLFSWIRRIGSPVNRIKMIRNYLRLMNILHDTDKGPSRKFAESYLRSDGCFLIQLIAINIGDLVAGDLICEMWQIYRHKRIQEFEELKFTSLNVESRLPSLMLNNTSNLNDYDKNGASNNNGN 478

[Close]

BLAST of Innexin vs. TrEMBL
Match: A0A1I8GCN3 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 295.434 bits (755), Expect = 2.136e-88
Identity = 162/411 (39.42%), Postives = 256/411 (62.29%), Query Frame = 2

Query:  263 MDERPSWRI---GKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQF----QTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDK--FLNKKYNNET---TKSCSKK---RCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLYRSQEKDEYEPLNSVDEINLSENKLKNV 1450
            MD    W++   G+I S+KLR  DDF+D+LNY+F+ +++ + I LI + QY  KPIQCW PQEFT+ WEEYA ++C +++TY     E    ++     + I Y QW  IVLAVQ ++F++PC+IWRL + +SGFN+++I+Q A + +V  P+ L K+I+F+A +M+   +  ++Y        K C  K    CC +    +L  +Y  IK+LYLLNV  QL ++++++GT Y+F+G     D+  G +   S   P+V  C  +  KL     YTLQCVLPLNMFLEKI++ LWFW+V++  +T  S ++W  ++   + ++ F+ +YLK+M +LK+++++  +KF+ +YLR DG+FI  LI+ N GDIVA D+  EL  +YR +       L  +D+  L     ++V
Sbjct:    1 MDATFMWKLSKLGRIGSSKLRFDDDFADRLNYQFTGVILFLFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYAENYCWVANTYYASVPEEHLPAEHLRRKRMITYYQWAPIVLAVQALMFYLPCLIWRLFMNYSGFNVRKILQMATDANVVIPEALNKNIRFMARYMEGCIYRQREYRRGVGVRVKHCLAKCSCLCCGKRYGNFLVVLYFFIKVLYLLNVFGQLYIMEKFVGTTYTFFGFQVLRDLFNGIQWYQSSNFPRVTFCDLQAKKLGVNYHYTLQCVLPLNMFLEKIYVFLWFWHVLVSIVTLGSFVNWFFRMAFARRRLIFVRKYLKIMNVLKDTDKTTSRKFVENYLRIDGVFIFRLIAMNCGDIVAGDLACELWSIYRHKR------LQELDDTKLETTDHRHV 405

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BLAST of Innexin vs. TrEMBL
Match: A0A1I8GJJ5 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 294.278 bits (752), Expect = 1.831e-86
Identity = 158/394 (40.10%), Postives = 248/394 (62.94%), Query Frame = 2

Query:  263 MDERPSWRI---GKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY---LNFDK--EFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRC--------CSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLYRSQEKDEYE 1396
            MD    W++   G+I S++ R+ DDF+D+LNY+FS +++ + I LI + QY  KPIQCW PQEFT+ WEEYA ++C +++TY   L  D   E +S S+  TI Y QW  IVLAVQ ++F+IPC+IWRL + +SGFN++R++Q A + +V  P+ L K+++F+A +M+  + ++   +       +RC        C +    +L  +Y  +K+LYLLN   QL ++++++GT ++F+G     D+++G     S   P+V  C  +  K+     YTLQCVLPLNMFLEKI++ LWFW  ++  IT  S +SW  ++   + +  F+ +YLK+M  LK+++    +KF+ +YLR DG+FI+ L+S N GDIVA D+  EL  +YR +   E E
Sbjct:   91 MDATFMWKLSKLGRIGSSRQRVDDDFADRLNYQFSGVILFLFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYAENYCWVANTYYASLEADHLPEEQSRSRL-TITYYQWAPIVLAVQALMFYIPCLIWRLFMNYSGFNVRRLLQMAADANVVIPEALNKNVRFMARYMEGCIYRQREYKRGLGVRVRRCLSACSCICCGKRHGNFLVVLYFFVKLLYLLNAFGQLYLMEKFVGTTHTFFGFRVLLDILQGVHWYRSSNFPRVTFCDLQARKIGVNYRYTLQCVLPLNMFLEKIYVFLWFWVALVSVITMSSFVSWFCRMAFARRRTGFVRKYLKIMNALKDTDRLTSRKFVENYLRVDGVFILRLVSANCGDIVAGDLACELWSIYRHKRLQELE 483

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BLAST of Innexin vs. TrEMBL
Match: A0A267EEW5 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 287.73 bits (735), Expect = 1.841e-85
Identity = 168/429 (39.16%), Postives = 260/429 (60.61%), Query Frame = 2

Query:  263 MDERPSWRI---GKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQF----QTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDK--FLNKKYNNETT---KSCSKKRCCSQNSRRY---LSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLYRSQEKDEYEPLNSVDEINLSENKLKNVEKIIGLEIPGKSYTNDNI 1504
            MD    W++   G+I S+KLR  DDF+D+LNY+F+ +++ + I LI + QY  KPIQCW PQEFT+ WEEYA ++C +++TY    +      Q       I Y QW  IVLAVQ ++F++PC+IWRL + +SGFNL++I+Q A + +V  P+ L K+++F+A +M+   +  ++Y        K C  K  C    +RY   L  +Y  IK+LYLLNV  QL +++++IGT Y+F+G     D+V G +   S   P+V  C  +  K  +   YTLQCVLPLNMFLEKI++ LWFW+V++  +T  S ++W  ++   + ++ FI +YLK+M +LK+++++  +KF+ +YLR DG+FI  LI+ N GDIVA D+  EL  +YR +       L  +D+  L  +         G+     +  +DNI
Sbjct:    1 MDATFMWKLSKLGRIGSSKLRFDDDFADRLNYQFTGVILFLFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYAENYCWVANTYYASVQADHLPPQHIRNELMITYYQWAPIVLAVQALMFYLPCLIWRLFMNYSGFNLRKILQMATDANVVIPEALNKNVRFMARYMEGCIYRQREYRRGVGVRLKHCLSKCSCLCCGKRYGNFLVVLYFFIKVLYLLNVFGQLYIMEKFIGTTYTFFGFRVLLDIVHGIKWYQSSNFPRVTFCDLQAKKEGQNYHYTLQCVLPLNMFLEKIYVFLWFWHVLVSIVTLTSFVNWFFRMAFARRRLNFIRKYLKIMNVLKDTDKTTSRKFVENYLRVDGVFIFRLIAMNCGDIVAGDLACELWSIYRHKR------LQELDDTKLEPDHRHTA--FAGMNATNGNNGDDNI 421

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BLAST of Innexin vs. TrEMBL
Match: A0A183ANF5 (Innexin OS=Echinostoma caproni OX=27848 GN=inx PE=3 SV=1)

HSP 1 Score: 280.411 bits (716), Expect = 8.962e-83
Identity = 140/343 (40.82%), Postives = 217/343 (63.27%), Query Frame = 2

Query:  410 AKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDK---EFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKK-YNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLYRSQEKDEYEPLNSVDEINL 1426
             KPIQCW PQEFT+ WEEYA ++C +S+TY    +         +   I Y QW  IV+A+Q + F++PC+IWRL +  SGFN++RI+Q A +++V  P+   K+++FIA +M+  + +  +   T  S +   CC +    YL  +Y  IK+LYL N+V QL M+++++G  Y+FYG+    D++KG E   S   P+V  C FE  KL +   YTLQCVLPLNMFLEKI+I LWFW+ ++G +T  S + W  ++     +V+FI +YLK+M +L++++++   KF+ +YLR DG+F++ LI+ NVGD++A D+  EL  +YR +   E E    +D   +
Sbjct:   17 GKPIQCWIPQEFTRGWEEYAENYCWVSNTYFAPIQNRLPPAPDREMLLIGYYQWAPIVMAIQAMAFYLPCLIWRLFMAQSGFNVRRILQMACDSNVLLPEHTMKNVRFIARYMEGCIYRHTFRAGTDGSGTGWGCCGKRHGNYLVVLYFFIKVLYLTNIVGQLFMMEKFVGNNYTFYGLRVLIDLIKGREWFHSGNFPRVTFCDFEAKKLGKNHKYTLQCVLPLNMFLEKIYIFLWFWHCMVGLVTLSSFIMWFYRMGFPNRRVKFIRKYLKIMSVLRDTDKAASHKFVENYLRPDGVFLIRLIAINVGDLMAGDLACELWHIYRHKRLHEAEDQKYLDATGM 359

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BLAST of Innexin vs. Ensembl Cavefish
Match: ENSAMXT00000047000.1 (pep primary_assembly:Astyanax_mexicanus-2.0:21:9985706:9990085:1 gene:ENSAMXG00000032330.1 transcript:ENSAMXT00000047000.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.5666 bits (192), Expect = 1.836e-14
Identity = 41/117 (35.04%), Postives = 66/117 (56.41%), Query Frame = 1

Query: 2017 HFNETTTSLPVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            H  + +   P + + RP+  + L+ VR    ELL  GII  S+S +SSP+ +V  K+G  R C DYR+LN+ T+ D+Y+   + + F  LT +  F  +DL    +Q+ V ++D  K
Sbjct:  347 HHIKLSDETPFKHRARPIHPQDLEAVRKHLQELLQAGIIRESESPFSSPIVVVRKKNGDVRLCIDYRKLNLQTVKDAYALPNLEETFSTLTGSKWFSVLDLKSGYYQIEVEETDKPK 463

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BLAST of Innexin vs. Ensembl Cavefish
Match: ENSAMXT00000038088.1 (pep primary_assembly:Astyanax_mexicanus-2.0:23:13869500:13874588:-1 gene:ENSAMXG00000037864.1 transcript:ENSAMXT00000038088.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.6406 bits (187), Expect = 7.309e-14
Identity = 41/117 (35.04%), Postives = 62/117 (52.99%), Query Frame = 1

Query: 2017 HFNETTTSLPVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            H   T  +LP R + RPL       +R    ++L++G+I  S S W++P+ +V  KDG++R C DYR+LN +T  D++    + +    LT A  F T+DL     QV V   D  K
Sbjct:  328 HCIPTGDALPSRERFRPLPPNMYQEMRVLLADMLDKGVISESSSPWAAPVVMVRKKDGSWRFCVDYRKLNAVTHKDAFPLPRIEETLTTLTQAEWFTTLDLASGYWQVGVHPDDQPK 444

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BLAST of Innexin vs. Ensembl Cavefish
Match: ENSAMXT00000048050.1 (pep primary_assembly:Astyanax_mexicanus-2.0:19:20134742:20139355:-1 gene:ENSAMXG00000043312.1 transcript:ENSAMXT00000048050.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.6406 bits (187), Expect = 9.077e-14
Identity = 42/140 (30.00%), Postives = 75/140 (53.57%), Query Frame = 1

Query: 1951 QLNTQKMYILKY-LQIDYFAPYNHFNETTTSLPVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            +LNT      ++ L   + +   H  + +   P + + RP+  + ++ VR    ELL  G+I  S+S +SSP+ +V  K+G  R C DYR+LN+ T+ D+Y+   + + F  LT +  F  +DL    +Q+ + ++D  K
Sbjct:  305 KLNTMPEVFAQHDLDFGHSSKVKHHIKLSDETPFKQRARPIHPQDINAVRLHLEELLEAGVIRESESSFSSPIVVVRKKNGDVRLCVDYRKLNLQTVKDAYALPNLEETFSVLTGSQWFSVLDLKSGYYQIELEEADKHK 444

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BLAST of Innexin vs. Ensembl Cavefish
Match: ENSAMXT00000047338.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:32004976:32009589:-1 gene:ENSAMXG00000038997.1 transcript:ENSAMXT00000047338.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.6406 bits (187), Expect = 9.077e-14
Identity = 42/140 (30.00%), Postives = 75/140 (53.57%), Query Frame = 1

Query: 1951 QLNTQKMYILKY-LQIDYFAPYNHFNETTTSLPVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            +LNT      ++ L   + +   H  + +   P + + RP+  + ++ VR    ELL  G+I  S+S +SSP+ +V  K+G  R C DYR+LN+ T+ D+Y+   + + F  LT +  F  +DL    +Q+ + ++D  K
Sbjct:  305 KLNTMPEVFAQHDLDFGHSSKVKHHIKLSDETPFKQRARPIHPQDINAVRLHLEELLEAGVIRESESSFSSPIVVVRKKNGDVRLCVDYRKLNLQTVKDAYALPNLEETFSVLTGSQWFSVLDLKSGYYQIELEEADKHK 444

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BLAST of Innexin vs. Ensembl Cavefish
Match: ENSAMXT00000048130.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000027.1:9314169:9318317:-1 gene:ENSAMXG00000039110.1 transcript:ENSAMXT00000048130.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.2554 bits (186), Expect = 1.073e-13
Identity = 37/108 (34.26%), Postives = 62/108 (57.41%), Query Frame = 1

Query: 2044 PVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            P + + RP+  +  D V+    ELL  G+I  S+S +SSP+ +V  K+G  R C DYR+LN+ T+ D+Y+   + + F  LT +  F  +DL    +Q+ + ++D  K
Sbjct:  189 PFKQRARPIHPQDFDAVKRHLEELLESGVIRESESSFSSPIVVVRKKNGEVRLCVDYRKLNLQTVKDAYALPHLEETFSVLTGSKWFSVLDLKSGYYQIELEEADKHK 296

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BLAST of Innexin vs. Ensembl Medaka
Match: ENSORLT00000040051.1 (pep primary_assembly:ASM223467v1:1:37354481:37359289:-1 gene:ENSORLG00000026212.1 transcript:ENSORLT00000040051.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.2629 bits (199), Expect = 3.269e-15
Identity = 42/104 (40.38%), Postives = 57/104 (54.81%), Query Frame = 1

Query: 2029 TTTSLPVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQV 2340
            TT  +PVRCK   +S  K   +     ++L  GII  S+S W +P+ LVP  DG+ R C DYRRLN  T  D+Y   L++D+   +  A  F T+DL     QV
Sbjct:  727 TTDEVPVRCKAYRVSPFKRKIITEHIDQMLKDGIIEPSQSAWGAPVVLVPKPDGSMRFCVDYRRLNAKTTADAYPMPLIHDLLESMHGAEFFSTLDLKSGYWQV 830

HSP 2 Score: 20.7866 bits (42), Expect = 3.269e-15
Identity = 7/14 (50.00%), Postives = 13/14 (92.86%), Query Frame = 3

Query: 2361 SKTAVLTFIGLFEY 2402
            +KTAV+T +GL+++
Sbjct:  838 AKTAVITPVGLYQF 851

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BLAST of Innexin vs. Ensembl Medaka
Match: ENSORLT00000033871.1 (pep primary_assembly:ASM223467v1:5:24767545:24770648:1 gene:ENSORLG00000024878.1 transcript:ENSORLT00000033871.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.337 bits (194), Expect = 1.027e-14
Identity = 43/108 (39.81%), Postives = 63/108 (58.33%), Query Frame = 1

Query: 2044 PVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            P + K RP+  + LD VR    EL + G+I  S+S +SSP+ +V  K+G  R C DYR+LNM TI D+Y+   + + F  LT +  F  +DL    +Q+ V + D QK
Sbjct:  186 PFKQKSRPIRPQDLDAVRRHLQELSHAGVIRESESSFSSPIVVVRKKNGDVRLCIDYRKLNMQTIKDAYALPNLEETFSALTGSKWFSVLDLKSGYYQIEVDEVDKQK 293

[Close]

BLAST of Innexin vs. Ensembl Medaka
Match: ENSORLT00000045829.1 (pep primary_assembly:ASM223467v1:10:30089555:30096892:1 gene:ENSORLG00000028614.1 transcript:ENSORLT00000045829.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.411 bits (189), Expect = 1.109e-14
Identity = 43/109 (39.45%), Postives = 58/109 (53.21%), Query Frame = 1

Query: 2014 NHFNETTTSLPVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQV 2340
             H   TT  LPVR +   +S +K   +     ++L  GII  S S W+SP+ LVP K G+ R C DYR LN  T HD+Y   LV++I   +  A  F ++DL     QV
Sbjct:  133 KHHIMTTDELPVRKRAYRVSPQKQAIIDEHLDKMLTNGIIEPSSSAWASPVVLVPKKCGSLRFCVDYRGLNAKTHHDAYPMPLVHEILESMQGAKYFSSLDLQSGYWQV 241

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BLAST of Innexin vs. Ensembl Medaka
Match: ENSORLT00000040080.1 (pep primary_assembly:ASM223467v1:4:6109106:6115792:1 gene:ENSORLG00000022989.1 transcript:ENSORLT00000040080.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.0258 bits (188), Expect = 6.332e-14
Identity = 38/108 (35.19%), Postives = 65/108 (60.19%), Query Frame = 1

Query: 2044 PVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            P + + RP+  + L+ VR    +LL+ G+I  S+S +SSP+ +V  K+G  R C DYR+LN+ T+ DSY+   + + F  L+ +  F  +DL    +Q+ + ++D QK
Sbjct:  370 PFKHRARPIHPQDLEAVRNHLQQLLDAGVIRESESPFSSPIVVVRKKNGDVRLCIDYRKLNLQTVKDSYALPNLEESFSALSGSHWFSVLDLKSGFYQIEMEEADKQK 477

[Close]

BLAST of Innexin vs. Ensembl Medaka
Match: ENSORLT00000036641.1 (pep primary_assembly:ASM223467v1:3:12394909:12399588:1 gene:ENSORLG00000024795.1 transcript:ENSORLT00000036641.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.6406 bits (187), Expect = 8.036e-14
Identity = 38/108 (35.19%), Postives = 65/108 (60.19%), Query Frame = 1

Query: 2044 PVRCKVRPLSNEKLDFVRAEFFELLNQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVNDIFCRLTDATIFYTIDLVKACHQVLVRKSDIQK 2367
            P + + RP+  + L+ VR    +LL+ G+I  S+S +SSP+ +V  K+G  R C DYR+LN+ T+ DSY+   + + F  L+ +  F  +DL    +Q+ + ++D QK
Sbjct:  370 PFKHRARPIHPQDLEAVRNHLQQLLHAGVIRESESPFSSPIVVVRKKNGDVRLCIDYRKLNLQTVKDSYALPNLEESFSALSGSHWFSVLDLKSGFYQIEMEEADKQK 477

[Close]

BLAST of Innexin vs. Planmine SMEST
Match: SMESG000055257.1 (SMESG000055257.1)

HSP 1 Score: 509.605 bits (1311), Expect = 2.332e-177
Identity = 258/259 (99.61%), Postives = 258/259 (99.61%), Query Frame = 2

Query:  263 MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA 1039
            MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFILIIVLIILIAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRI QAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA
Sbjct:    1 MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFILIIVLIILIAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRITQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA 259

[Close]

BLAST of Innexin vs. Planmine SMEST
Match: SMESG000055257.1 (SMESG000055257.1)

HSP 1 Score: 446.432 bits (1147), Expect = 4.999e-153
Identity = 232/259 (89.58%), Postives = 232/259 (89.58%), Query Frame = 2

Query:  263 MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA 1039
            MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFILIIVLIILIAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRI QAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSR                          RYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA
Sbjct:    1 MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFILIIVLIILIAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRITQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSR--------------------------RYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA 233

[Close]

BLAST of Innexin vs. Planmine SMEST
Match: SMESG000055266.1 (SMESG000055266.1)

HSP 1 Score: 441.81 bits (1135), Expect = 2.224e-148
Identity = 246/376 (65.43%), Postives = 276/376 (73.40%), Query Frame = 2

Query:  410 AKPIQCWTPQEFTKSWEEYARDFCGISDTYLN-FDKEFKSGSQFQ--TINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLNKKYNNETTKSCSKKR--------CCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLYRSQEKDEYEPLNSVDEINLSENKLKNVEKIIGLEIPGKSYTNDNI 1504
             KPIQCW PQEFT+ WEEYA  +C ISDTY N  D+     +  Q   I+Y QW SIVLAVQ +LFFIPCMIWRLLIL SGFNLQRIMQ A + +   PD L+KSIKFIAIHMDK L +K    T      KR        CC++NS  YLS VYIIIK+LYLLNVV QL ++QR+IGT YSFYGI   YD+V G E R S + P++  C F+  KL +   YTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKL+NRK K RFI +YLKLMEL+K+SEES  K FIFDYLRTDGLFIMHLIS NVGDIVAAD+V EL +LYRSQ  +E EP  S DE NLS  K  NV K I  EIPGK  TND+I
Sbjct:   43 GKPIQCWIPQEFTRGWEEYAESYCWISDTYFNPVDRRLPKLTDRQDVKISYYQWASIVLAVQALLFFIPCMIWRLLILQSGFNLQRIMQVAKDANAIIPDHLQKSIKFIAIHMDKCLKRKKIYGTGYKAKFKRLLSYVNGGCCARNSGNYLSFVYIIIKVLYLLNVVGQLYLMQRFIGTSYSFYGIQVLYDLVTGIEWRKSGHFPRITFCDFKTKKLGKNHIYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLMNRKHKFRFIRDYLKLMELVKKSEESWRKNFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFKSYDETNLSGYKFINVNKEICAEIPGKIDTNDDI 418

[Close]

BLAST of Innexin vs. Planmine SMEST
Match: SMESG000024134.1 (SMESG000024134.1)

HSP 1 Score: 441.039 bits (1133), Expect = 2.900e-148
Identity = 254/409 (62.10%), Postives = 297/409 (72.62%), Query Frame = 2

Query:  284 RIGKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY-LNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFL-NKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLYRSQEKDEYEPLNSVDEINLSENKLKNVEKIIGLEIPGKSYTNDNI 1504
            ++G+I SN++RL+DDFSD++NY+FS ILIIVLI L  V QYF KPIQCW PQEF+  WEEY+  +C IS TY +N      +  Q   I+Y QW SIVLAVQ +LFFIPCM+WRLLIL SGFNLQRIMQ A + +V  PD L+KSIKFIAIHMDK L +KK      K+  K+  C+      L  VYIIIK+LYLLN++ QL ++QR+IGT YSFYGI   YD++ G     S   P+V  C F   KL +   YT+QCVLP NMFLEKIFI LWFWNVIIGCITAVSL  WLNKL+ RK K RFIG+YLKLM L K SEES  + FIFDYLRTDGLFIMHLIS NVGDIVAAD+V EL +LYRSQ ++E EPL S DE N S  KL NV K I  EIPGK  TND+I
Sbjct:    3 KLGRIGSNRIRLVDDFSDRINYQFSSILIIVLISLTGVWQYFGKPIQCWIPQEFSTGWEEYSESYCWISGTYPVNRRLPELTDKQDVQISYYQWTSIVLAVQALLFFIPCMMWRLLILQSGFNLQRIMQVAVDANVIIPDHLQKSIKFIAIHMDKCLKSKKIYGTGYKAKFKRLFCN------LLFVYIIIKVLYLLNIIGQLYLMQRFIGTSYSFYGIQVLYDLMTGIGWPQSGNFPRVTFCDFTAKKLGKNHIYTIQCVLPFNMFLEKIFIFLWFWNVIIGCITAVSLFCWLNKLMTRKLKFRFIGDYLKLMGLAKNSEESWKENFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRQNECEPLKSYDETNFSGYKLINVNKEICAEIPGKIDTNDDI 405

[Close]

BLAST of Innexin vs. Planmine SMEST
Match: SMESG000060499.1 (SMESG000060499.1)

HSP 1 Score: 316.62 bits (810), Expect = 4.220e-99
Identity = 168/394 (42.64%), Postives = 253/394 (64.21%), Query Frame = 2

Query:  284 RIGKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY---LNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSF-PDQLKKSIKFIAIHMD-------------KFLNKKYNNETTKSCSKKR----CCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISTNVGDIVAADIVGELLDLYRSQEKDEYEPL 1402
            ++G+I SNKLR  DDF D+LNY+F+ +L+ + I LI + QY  KPIQCW PQEFT+ WEEY  ++C +S+TY   +      K   + Q I Y QW  I+L +Q +LF+IPC+IWR +   SGFN++RI+Q A++ + S  P+QL+KSI FIA HMD              F+       T   C  K     C  +    +L+ +YI IKILYL+N++ QL +++++IGT+Y+FYGI   +D+++G+E   S   P+V  C  E  KL +   Y+LQCVLP+NMFLEKI+I LWFW+VI+G  T  SL SW+ ++ +  ++++ I  YL+LM +L ++++   +KF   YLR+DG F++ LI+ N+GD+VA D++ E+  +YR +   E+E L
Sbjct:   49 KLGRIGSNKLRFDDDFVDRLNYQFTGLLLFMFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYTENYCWVSNTYFASIQNRMPSKDARKEQMIGYYQWAPILLGLQSLLFYIPCLIWRNVSPQSGFNVRRILQVASDANCSLIPEQLQKSISFIARHMDTCLYRHRICYEHKHFMRTNGKRSTISRCLAKLRCICCLGKLQGNFLTVLYISIKILYLINIIGQLYLMEKFIGTKYAFYGIRVLWDLMRGHEWHYSGNFPRVTFCDLEAKKLGKNHLYSLQCVLPMNMFLEKIYIFLWFWHVIVGIATLFSLFSWIKRIGSPVNRIKMIRNYLRLMNILHDTDKGPSRKFAESYLRSDGCFLIQLIAINIGDLVAGDLICEMWQIYRHKRIQEFEEL 442

The following BLAST results are available for this feature:

BLAST of Innexin vs. Ensembl Human
BLAST of Innexin vs. Ensembl Celegans
BLAST of Innexin vs. Ensembl Fly
BLAST of Innexin vs. Ensembl Zebrafish
BLAST of Innexin vs. Ensembl Xenopus
BLAST of Innexin vs. Ensembl Mouse
BLAST of Innexin vs. UniProt/SwissProt
BLAST of Innexin vs. TrEMBL
BLAST of Innexin vs. Ensembl Cavefish
BLAST of Innexin vs. Ensembl Sea Lamprey
BLAST of Innexin vs. Ensembl Yeast
BLAST of Innexin vs. Ensembl Nematostella
BLAST of Innexin vs. Ensembl Medaka
BLAST of Innexin vs. Planmine SMEST

BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
inx-1	3.856e-65	35.03	Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394]	[more]
inx-1	3.856e-65	35.03	Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394]	[more]
inx-1	1.409e-64	35.59	Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394]	[more]
inx-13	1.291e-60	30.91	Innexin [Source:UniProtKB/TrEMBL;Acc:O44887]	[more]
unc-9	2.833e-60	31.15	Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O0...	[more]

BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Inx2	3.317e-11	23.75	gene:FBgn0027108 transcript:FBtr0301860	[more]
Inx2	3.317e-11	23.75	gene:FBgn0027108 transcript:FBtr0071005	[more]
Inx2	3.317e-11	23.75	gene:FBgn0027108 transcript:FBtr0332314	[more]
Inx2	3.317e-11	23.75	gene:FBgn0027108 transcript:FBtr0071006	[more]
Inx3	7.835e-11	22.80	gene:FBgn0265274 transcript:FBtr0085350	[more]

BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CR749164.1	2.892e-10	35.19	pep chromosome:GRCz11:21:30355767:30361679:1 gene:...	[more]
BX546500.1	1.051e-9	35.19	pep chromosome:GRCz11:23:12926092:12931693:-1 gene...	[more]
BX511224.1	1.074e-9	35.19	pep chromosome:GRCz11:2:18017000:18022765:1 gene:E...	[more]
CR855320.1	1.112e-9	35.19	pep chromosome:GRCz11:1:7956030:7961696:1 gene:ENS...	[more]
BX511082.1	1.484e-9	35.24	pep chromosome:GRCz11:9:14291932:14297132:1 gene:E...	[more]

BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
anxa6	1.491e-14	35.59	annexin A6 [Source:Xenbase;Acc:XB-GENE-989741]	[more]
ENSXETT00000023941.1	1.516e-13	37.04	pep primary_assembly:Xenopus_tropicalis_v9.1:KV463...	[more]
vdac1	7.033e-12	34.55	voltage-dependent anion channel 1 [Source:Xenbase;...	[more]
ENSXETT00000003703.1	7.265e-12	34.58	pep primary_assembly:Xenopus_tropicalis_v9.1:8:329...	[more]
alkbh5	9.013e-12	33.33	alkB homolog 5, RNA demethylase [Source:Xenbase;Ac...	[more]

BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O01393\|UNC9_CAEEL	3.604e-59	31.15	Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN...	[more]
sp\|Q03412\|UNC7_CAEEL	2.573e-51	31.67	Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN...	[more]
sp\|Q23027\|INX5_CAEEL	1.376e-50	28.93	Innexin-5 OS=Caenorhabditis elegans OX=6239 GN=inx...	[more]
sp\|Q23157\|INX11_CAEEL	3.099e-49	31.43	Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=in...	[more]
sp\|Q27295\|EAT5_CAEEL	3.950e-47	28.07	Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN...	[more]

BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q2L6N1	1.291e-95	40.59	Innexin OS=Dugesia japonica OX=6161 GN=inx3 PE=2 S...	[more]
A0A1I8GCN3	2.136e-88	39.42	Innexin OS=Macrostomum lignano OX=282301 GN=inx PE...	[more]
A0A1I8GJJ5	1.831e-86	40.10	Innexin OS=Macrostomum lignano OX=282301 GN=inx PE...	[more]
A0A267EEW5	1.841e-85	39.16	Innexin OS=Macrostomum lignano OX=282301 GN=inx PE...	[more]
A0A183ANF5	8.962e-83	40.82	Innexin OS=Echinostoma caproni OX=27848 GN=inx PE=...	[more]

BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000047000.1	1.836e-14	35.04	pep primary_assembly:Astyanax_mexicanus-2.0:21:998...	[more]
ENSAMXT00000038088.1	7.309e-14	35.04	pep primary_assembly:Astyanax_mexicanus-2.0:23:138...	[more]
ENSAMXT00000048050.1	9.077e-14	30.00	pep primary_assembly:Astyanax_mexicanus-2.0:19:201...	[more]
ENSAMXT00000047338.1	9.077e-14	30.00	pep primary_assembly:Astyanax_mexicanus-2.0:9:3200...	[more]
ENSAMXT00000048130.1	1.073e-13	34.26	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000040051.1	3.269e-15	40.38	pep primary_assembly:ASM223467v1:1:37354481:373592...	[more]
ENSORLT00000033871.1	1.027e-14	39.81	pep primary_assembly:ASM223467v1:5:24767545:247706...	[more]
ENSORLT00000045829.1	1.109e-14	39.45	pep primary_assembly:ASM223467v1:10:30089555:30096...	[more]
ENSORLT00000040080.1	6.332e-14	35.19	pep primary_assembly:ASM223467v1:4:6109106:6115792...	[more]
ENSORLT00000036641.1	8.036e-14	35.19	pep primary_assembly:ASM223467v1:3:12394909:123995...	[more]

BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000055257.1	2.332e-177	99.61	SMESG000055257.1	[more]
SMESG000055257.1	4.999e-153	89.58	SMESG000055257.1	[more]
SMESG000055266.1	2.224e-148	65.43	SMESG000055266.1	[more]
SMESG000024134.1	2.900e-148	62.10	SMESG000024134.1	[more]
SMESG000060499.1	4.220e-99	42.64	SMESG000060499.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30004277 ID=SMED30004277|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=2403bp
AATCTAATAAAAGTTGTAAATATTTTTCACTTGAAATTTGGAGTTTAAAT
ATTTATCATAATTTTGTACTGTTTTTCATTAAAGTTCTAATCTTGATTTA
TCATGCAAATATAAATTTATTGTGTTAGAAATTTATTATGCATTATCACT
ATTAAAACAGCTATCAAATATTTTCCAGGCCTTACAATTATCGGACAACA
GAATCTCCAATATAAAACTGATATAGAAAACTATTATCACGCAAAGTCGC
AATCTAACAGAAATGGATGAAAGACCTTCTTGGAGAATCGGGAAAATCAG
ATCCAACAAATTAAGACTTATTGATGACTTTTCTGATAAATTAAATTACA
AATTTTCTTTTATATTGATAATTGTTTTAATTATTCTGATAGCTGTGAAC
CAATACTTCGCTAAGCCAATTCAGTGTTGGACTCCTCAAGAATTTACAAA
AAGTTGGGAAGAATATGCACGAGACTTTTGCGGAATATCAGACACCTATC
TCAATTTTGATAAAGAATTTAAATCTGGTAGTCAGTTTCAAACAATAAAT
TATATTCAATGGATATCTATTGTACTGGCAGTTCAAGGAATTTTGTTCTT
CATTCCTTGTATGATATGGCGTTTGTTGATCTTACACTCTGGATTTAATC
TTCAACGAATAATGCAAGCTGCTAATAACACCCATGTCAGTTTTCCTGAT
CAACTAAAAAAAAGCATTAAATTTATTGCAATTCATATGGATAAATTTTT
GAATAAAAAATACAATAATGAAACAACTAAATCGTGCAGTAAAAAAAGGT
GTTGTAGTCAGAATTCAAGAAGGTATCTCTCATCGGTTTATATCATTATT
AAAATACTTTATTTACTTAATGTTGTTTTTCAACTTTGCATGATTCAAAG
ATATATTGGCACACGTTATTCCTTCTATGGGATAGATGCTTTTTATGATA
TGGTAAAAGGAAATGAATTGAGAAGTTCAGATTATCTTCCAAAAGTTAAA
CTTTGCAAATTTGAAATAACTAAATTAAACAGAAGAGCATTCTATACTCT
ACAATGCGTATTGCCGTTGAACATGTTTCTTGAGAAAATATTCATTTTAC
TCTGGTTTTGGAACGTAATAATCGGCTGTATCACCGCTGTCAGTTTGTTG
AGTTGGTTGAACAAATTAGTTAACAGAAAGGACAAAGTCCGATTCATCGG
AGAATATCTTAAATTGATGGAGTTGCTAAAAGAATCCGAAGAATCTTTGG
TAAAAAAGTTCATTTTCGACTACTTACGAACGGATGGATTATTTATAATG
CATTTGATATCTACCAATGTCGGTGATATTGTGGCAGCTGACATAGTTGG
CGAACTGTTGGATTTGTACCGCTCCCAAGAAAAGGACGAATATGAACCTT
TAAACTCAGTAGACGAGATAAATTTAAGTGAAAACAAATTAAAAAATGTT
GAAAAAATAATTGGCTTGGAAATTCCCGGAAAAAGCTACACGAATGATAA
CATTTTTTGATTTGATTCTGTTAATTAATTTTGGGATTTACTATTATGCC
AAATCTTTTTTTTTTAACAATTTTCCTGATTTTTTTGTTTTACTAGTGTT
TTATAAAAAATCTAAAAATTCATTGGGTGTAAATTTTAAATTTTGAATGT
TGTTTTTACCAGGATATTTATTATTGTGCAAATTGAGTGTGATGAAAATT
TTGTTTAAAAAACGAACGACAACTGATGTGGAAAATAATTGAAAAACAAA
AGACGATTGATTTTTAATATTAAATTTGTAATATGGTTGCTCATGTTAAA
TCCGTTTGCATTTAATTATTTTCCAACTTTTTGAATTATTACTCCGGACA
TGTATTTTTTAATGGAATTTGGAGATCACCAAACTGTCGCAGTACACAGT
GATACAGTGTATAGAACCACCTGACTAGCATATATCGCAAAATGCCGTAA
CAGCTAAACACACAAAAAATGTACATCCTAAAATATCTTCAAATCGACTA
TTTTGCACCTTATAACCATTTCAATGAAACTACCACTTCTCTCCCTGTCC
GTTGTAAAGTGCGCCCACTTTCTAATGAAAAACTTGACTTTGTTCGTGCT
GAATTCTTTGAATTATTAAATCAAGGAATCATTCTGAGATCGAAATCACT
TTGGTCTTCACCGCTATATCTCGTTCCAAATAAAGATGGTACTTTCCGAC
CTTGTAGCGATTACCGTCGATTGAATATGATCACAATACACGATTCTTAT
TCCAACTGTTTAGTCAACGACATTTTTTGCAGGCTCACGGACGCAACTAT
ATTTTATACAATAGATCTCGTCAAGGCATGCCACCAAGTACTCGTCAGAA
AATCAGACATTCAAAAACAGCAGTGTTAACCTTTATCGGTCTTTTCGAAT
ATA

protein sequence of SMED30004277-orf-1

>SMED30004277-orf-1 ID=SMED30004277-orf-1|Name=SMED30004277-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=416bp
MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFILIIVLIILIAVNQYFA
KPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQW
ISIVLAVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKK
SIKFIAIHMDKFLNKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILY
LLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKF
EITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLN
KLVNRKDKVRFIGEYLKLMELLKESEESLVKKFIFDYLRTDGLFIMHLIS
TNVGDIVAADIVGELLDLYRSQEKDEYEPLNSVDEINLSENKLKNVEKII
GLEIPGKSYTNDNIF*

protein sequence of SMED30004277-orf-2

>SMED30004277-orf-2 ID=SMED30004277-orf-2|Name=SMED30004277-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=137bp
MYILKYLQIDYFAPYNHFNETTTSLPVRCKVRPLSNEKLDFVRAEFFELL
NQGIILRSKSLWSSPLYLVPNKDGTFRPCSDYRRLNMITIHDSYSNCLVN
DIFCRLTDATIFYTIDLVKACHQVLVRKSDIQKQQC*

Aliases

The feature 'Innexin' has the following synonyms


Synonym
Dj-inx3

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000429	neoblast
PLANA:0002075	pigment cell
PLANA:0002142	parenchyma
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR000990	Innexin

Vocabulary: **cellular component**
Term	Definition
GO:0005921	gap junction
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction

Vocabulary: **biological process**
Term	Definition
GO:0006810	transport
GO:0006811	ion transport

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000990	Innexin	PRINTS	PR01262	INNEXIN	coord: 97..119 score: 43.13 coord: 265..281 score: 63.06 coord: 241..250 score: 40.4 coord: 44..55 score: 38.67 coord: 193..207 score: 48.8
IPR000990	Innexin	PFAM	PF00876	Innexin	coord: 21..367 e-value: 6.3E-96 score: 321.7
IPR000990	Innexin	PANTHER	PTHR11893	INNEXIN	coord: 15..380
IPR000990	Innexin	PROSITE	PS51013	PANNEXIN	coord: 16..375 score: 30.553
None	No IPR available	PANTHER	PTHR11893:SF36	INNEXIN-5	coord: 15..380
None	No IPR available	TMHMM	TMhelix		coord: 277..299
None	No IPR available	TMHMM	TMhelix		coord: 31..50
None	No IPR available	TMHMM	TMhelix		coord: 189..211
None	No IPR available	TMHMM	TMhelix		coord: 101..123

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Innexin

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Owlery

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