Rho GTPase-activating protein 21

Overview


Name	Rho GTPase-activating protein 21
Smed ID	SMED30004269
Length (bp)	3335

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Rho GTPase-activating protein 21 (SMED30004269) t-SNE clustered cells

Violin plots show distribution of expression levels for Rho GTPase-activating protein 21 (SMED30004269) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Rho GTPase-activating protein 21 (SMED30004269) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Rho GTPase-activating protein 21 (SMED30004269) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30004269

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30004269	SMESG000041589.1	dd_Smed_v4_3818_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30004269	SMESG000041589.1	dd_Smed_v4_3818_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30004269	SMESG000041589.1	dd_Smed_v4_3818_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30004269	SMESG000041589.1	dd_Smed_v4_3818_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30004269	SMESG000041589.1	dd_Smed_v4_3818_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30004269	SMESG000041589.1	dd_Smed_v4_3818_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Human
Match: ARHGAP23 (Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:HGNC:29293])

HSP 1 Score: 103.219 bits (256), Expect = 1.624e-21
Identity = 59/231 (25.54%), Postives = 104/231 (45.02%), Query Frame = 3

Query: 1962 FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDP-KSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRV 2651
            F   + E      N ++P+I+  C +IVE  GL   GIYR+ GN  V+ +L   LN+ P +I+     W +++ I  +LK F RKL + L   D  +    + +  D  +  ++L K + D+  H                           ++TL++L+ HL  +  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H DW F D     +R 
Sbjct:  903 FGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHY--------------------------YETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFSDEEDKGERT 1107

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Query: 1962 FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDP-KSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRV 2651
            F   + E      N ++P+I+  C +IVE  GL   GIYR+ GN  V+ +L   LN+ P +I+     W +++ I  +LK F RKL + L   D  +    + +  D  +  ++L K + D+  H                           ++TL++L+ HL  +  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H DW F D     +R 
Sbjct:  903 FGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHY--------------------------YETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFSDEEDKGERT 1107

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Human
Match: ARHGAP21 (Rho GTPase activating protein 21 [Source:HGNC Symbol;Acc:HGNC:23725])

HSP 1 Score: 102.449 bits (254), Expect = 1.683e-21
Identity = 67/226 (29.65%), Postives = 104/226 (46.02%), Query Frame = 3

Query: 1950 TGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            TGT F   + + P    N  IP+I+ +C K+VE  GL   GIYR+ GN   I ++   LNK  ++ID    +W +++ I  +LK F RKL + L   D     A   +A   +DP    KTL  +                      IHD  +  ++TL++L  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++ H DW F +
Sbjct:  591 TGT-FGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTND---KYADFIEANRKEDPLDRLKTLKRL----------------------IHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDWFFTE 790

HSP 2 Score: 21.9422 bits (45), Expect = 1.683e-21
Identity = 13/29 (44.83%), Postives = 15/29 (51.72%), Query Frame = 2

Query: 1865 HWYKGRF*RIQKTTGKWNITTGTGFFRLD 1951
            HW KG    ++KT  K    TGT   RLD
Sbjct:  571 HWRKGIPSIMRKTFEKKPTATGTFGVRLD 599

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Human
Match: ARHGAP23 (Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:HGNC:29293])

HSP 1 Score: 102.834 bits (255), Expect = 1.955e-21
Identity = 59/231 (25.54%), Postives = 104/231 (45.02%), Query Frame = 3

Query: 1962 FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDP-KSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRV 2651
            F   + E      N ++P+I+  C +IVE  GL   GIYR+ GN  V+ +L   LN+ P +I+     W +++ I  +LK F RKL + L   D  +    + +  D  +  ++L K + D+  H                           ++TL++L+ HL  +  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H DW F D     +R 
Sbjct:  903 FGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHY--------------------------YETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFSDEEDKGERT 1107

[Close]

Query: 1962 FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDP-KSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRV 2651
            F   + E      N ++P+I+  C +IVE  GL   GIYR+ GN  V+ +L   LN+ P +I+     W +++ I  +LK F RKL + L   D  +    + +  D  +  ++L K + D+  H                           ++TL++L+ HL  +  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H DW F D     +R 
Sbjct:  903 FGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHY--------------------------YETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFSDEEDKGERT 1107

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Celegans
Match: tag-325 (WW domain-containing protein tag-325 [Source:UniProtKB/Swiss-Prot;Acc:P46941])

HSP 1 Score: 71.2478 bits (173), Expect = 7.648e-13
Identity = 68/265 (25.66%), Postives = 115/265 (43.40%), Query Frame = 3

Query: 1731 SKSSTENISNNPPTELSPSPSKNILKQALEKIRPEKKPNKSYEVFTGTKADFEEFKKQLESGILPPELDSSDLTGTNFNRYI-HEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVV 2522
            S+S+ E +S +  T+  P PSK  +   +EK+R           F  T+   E  K   E GI  PE     + G+  +    HE      N  +P  I + T+++E+ GL  +GIYR+SGN   ++ +    +++  +   +L    ++H + G LKLF R+L   L P  L                          + + S+ Q  +      K    +    +   +TL+ LL+HL++V S+   N M +H L+I F P +
Sbjct:   40 SQSAIETVSTSVSTD-EPRPSKETI---IEKLR----------RFFRTRPTVESLK---EKGIYKPE----PVFGSTLSAICQHE------NSLVPKFIRVITEVIESKGLETDGIYRVSGNLSAVQKIRCQADQDNYK---ALVSEEDIHVLTGALKLFFRELTDPLFPISLH-------------------------KEYTSAMQMPNATTRFKKFEELLSRLPNENRETLKMLLRHLNRVASHSSQNRMQQHNLAIVFGPTL 249

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Celegans
Match: pac-1 (GTPase-activating protein pac-1 [Source:UniProtKB/Swiss-Prot;Acc:P34288])

HSP 1 Score: 71.2478 bits (173), Expect = 3.037e-12
Identity = 65/268 (24.25%), Postives = 111/268 (41.42%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHL-NKNPSEIDSSLAE-----WNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRVRNTELMN--NAFEYATKYIAKKYDISIRNDVSGEIASKNFDVNNLVWK 2789
            +PMI+  C  ++E  G+   GIYRI GN   +  L   L N+    +D S  E     W +V+ +  +LK+FLRKL + L+   L          +D +   +    L  +R  L                          + TL++L+ HLS++  +   N M+   L++ F P ++     N+  +        K +E ++ +  W+F + +T  D V      +  N  E         Y + +   VS   AS N D++NL+ K
Sbjct:  123 VPMIVQACVCVIETYGMDTVGIYRIPGNTAAVNALKESLSNRGFDSVDLSKVESLDPRWRDVNVVSSLLKMFLRKLPEPLLTDKLYPFF------IDANRISTHHNRLHKLRNLLRKLPRP-------------------HYDTLRFLIVHLSEITKHSDVNKMECRNLALMFGPSIVRPSDDNMATMVTHMSDQCKIIETLIHYNLWMFDESSTTEDAVPEQHPADGQNPLEPG------GYGVGVPTGVSA--ASFN-DMHNLIRK 356

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Celegans
Match: pac-1 (GTPase-activating protein pac-1 [Source:UniProtKB/Swiss-Prot;Acc:P34288])

HSP 1 Score: 70.8626 bits (172), Expect = 5.135e-12
Identity = 53/220 (24.09%), Postives = 93/220 (42.27%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHL-NKNPSEIDSSLAE-----WNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRV 2651
            +PMI+  C  ++E  G+   GIYRI GN   +  L   L N+    +D S  E     W +V+ +  +LK+FLRKL + L+   L          +D +   +    L  +R  L                          + TL++L+ HLS++  +   N M+   L++ F P ++     N+  +        K +E ++ +  W+F + +T  D V
Sbjct: 1075 VPMIVQACVCVIETYGMDTVGIYRIPGNTAAVNALKESLSNRGFDSVDLSKVESLDPRWRDVNVVSSLLKMFLRKLPEPLLTDKLYPFF------IDANRISTHHNRLHKLRNLLRKLPRP-------------------HYDTLRFLIVHLSEITKHSDVNKMECRNLALMFGPSIVRPSDDNMATMVTHMSDQCKIIETLIHYNLWMFDESSTTEDAV 1269

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Celegans
Match: pac-1 (GTPase-activating protein pac-1 [Source:UniProtKB/Swiss-Prot;Acc:P34288])

HSP 1 Score: 70.8626 bits (172), Expect = 5.239e-12
Identity = 53/220 (24.09%), Postives = 93/220 (42.27%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHL-NKNPSEIDSSLAE-----WNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRV 2651
            +PMI+  C  ++E  G+   GIYRI GN   +  L   L N+    +D S  E     W +V+ +  +LK+FLRKL + L+   L          +D +   +    L  +R  L                          + TL++L+ HLS++  +   N M+   L++ F P ++     N+  +        K +E ++ +  W+F + +T  D V
Sbjct:  600 VPMIVQACVCVIETYGMDTVGIYRIPGNTAAVNALKESLSNRGFDSVDLSKVESLDPRWRDVNVVSSLLKMFLRKLPEPLLTDKLYPFF------IDANRISTHHNRLHKLRNLLRKLPRP-------------------HYDTLRFLIVHLSEITKHSDVNKMECRNLALMFGPSIVRPSDDNMATMVTHMSDQCKIIETLIHYNLWMFDESSTTEDAV 794

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Celegans
Match: chin-1 (CHImaeriN (Rac-GTPase-activating protein) homolog [Source:UniProtKB/TrEMBL;Acc:Q965N4])

HSP 1 Score: 69.707 bits (169), Expect = 5.324e-12
Identity = 57/187 (30.48%), Postives = 83/187 (44.39%), Query Frame = 3

Query: 1992 MMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSS----LAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNS---SCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMES 2531
            M H   +P I+ LC   VE+ GL  EGIYR+SG+         H+ K   + DS+    LA   ++H +CG+LKL+ R L Q LIP                    S+ K L      L +YQ +   S  + E ++   + +  D    TL  +L HL KV  +   N M    L+  F+P +  S
Sbjct:  241 MAHGADLPPIVPLCIGEVESRGLDVEGIYRVSGSY-------DHMEKLKQQFDSNQYVDLATVCDIHTVCGLLKLYFRLLPQQLIPF-------------------SVHKQL------LVAYQETNQRSTHERERQIRKVMMELSDANIITLGAVLAHLKKVADHSAKNKMTVENLATIFSPTLFCS 395

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Fly
Match: RhoGAP5A (gene:FBgn0029778 transcript:FBtr0070785)

HSP 1 Score: 77.7962 bits (190), Expect = 2.262e-14
Identity = 58/185 (31.35%), Postives = 85/185 (45.95%), Query Frame = 3

Query: 2007 KIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAY-SCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQ--KNLTD 2552
            +IP ++  C + VE  G+ QEGIYR+SG    I  L   L++   + D S   + NV+ I G LKL+LR     L+P  L    AY S  A      ++  + LM          + SC                     LQY+L+HL +V S+   N M+EH L+  F P ++ + Q   NLT+
Sbjct:  317 QIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDREGEKTDMSETAYGNVNVIAGTLKLYLR-----LLPVPLITFQAYPSFMAAGRTGKQAEQRQLMAEAVRRLPPAHHSC---------------------LQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATPQHMTNLTE 475

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Fly
Match: RhoGAP19D (gene:FBgn0031118 transcript:FBtr0301537)

HSP 1 Score: 78.9518 bits (193), Expect = 2.292e-14
Identity = 53/209 (25.36%), Postives = 96/209 (45.93%), Query Frame = 3

Query: 2001 NPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAE--WNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            N  +P ++ +CT IVE  GL   GIYRI GN+  I  L   +N    + +S  ++  W +V+ +  +LKLF+R L   L+PA      +Y    ++ D    L + ++ +R  + S                        ++T+++L++HL +V      N M+   L+I F P ++ +    L     D +   + +EL++   D+ F
Sbjct: 1209 NAYVPHLVEVCTNIVETKGLGVVGIYRIPGNKAAISELSELVNTKDFQFESCASDDRWEDVNVVSSLLKLFIRSLPDALMPA------SYYINFIEADKKFGLERIVL-LREIVESLPRHP-------------------YETMKHLIRHLCRVSGNCDVNRMEPKNLAIIFGPSIIRTPNDTLETAVKDMKHQCRIVELLVTQYDYFF 1391

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Fly
Match: RhoGAP19D (gene:FBgn0031118 transcript:FBtr0345015)

HSP 1 Score: 78.9518 bits (193), Expect = 2.297e-14
Identity = 53/209 (25.36%), Postives = 96/209 (45.93%), Query Frame = 3

Query: 2001 NPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAE--WNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            N  +P ++ +CT IVE  GL   GIYRI GN+  I  L   +N    + +S  ++  W +V+ +  +LKLF+R L   L+PA      +Y    ++ D    L + ++ +R  + S                        ++T+++L++HL +V      N M+   L+I F P ++ +    L     D +   + +EL++   D+ F
Sbjct: 1235 NAYVPHLVEVCTNIVETKGLGVVGIYRIPGNKAAISELSELVNTKDFQFESCASDDRWEDVNVVSSLLKLFIRSLPDALMPA------SYYINFIEADKKFGLERIVL-LREIVESLPRHP-------------------YETMKHLIRHLCRVSGNCDVNRMEPKNLAIIFGPSIIRTPNDTLETAVKDMKHQCRIVELLVTQYDYFF 1417

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Fly
Match: RhoGAP19D (gene:FBgn0031118 transcript:FBtr0304906)

HSP 1 Score: 78.9518 bits (193), Expect = 2.297e-14
Identity = 53/209 (25.36%), Postives = 96/209 (45.93%), Query Frame = 3

Query: 2001 NPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAE--WNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            N  +P ++ +CT IVE  GL   GIYRI GN+  I  L   +N    + +S  ++  W +V+ +  +LKLF+R L   L+PA      +Y    ++ D    L + ++ +R  + S                        ++T+++L++HL +V      N M+   L+I F P ++ +    L     D +   + +EL++   D+ F
Sbjct: 1235 NAYVPHLVEVCTNIVETKGLGVVGIYRIPGNKAAISELSELVNTKDFQFESCASDDRWEDVNVVSSLLKLFIRSLPDALMPA------SYYINFIEADKKFGLERIVL-LREIVESLPRHP-------------------YETMKHLIRHLCRVSGNCDVNRMEPKNLAIIFGPSIIRTPNDTLETAVKDMKHQCRIVELLVTQYDYFF 1417

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Fly
Match: RhoGAP19D (gene:FBgn0031118 transcript:FBtr0340405)

HSP 1 Score: 78.9518 bits (193), Expect = 2.473e-14
Identity = 53/209 (25.36%), Postives = 96/209 (45.93%), Query Frame = 3

Query: 2001 NPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAE--WNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            N  +P ++ +CT IVE  GL   GIYRI GN+  I  L   +N    + +S  ++  W +V+ +  +LKLF+R L   L+PA      +Y    ++ D    L + ++ +R  + S                        ++T+++L++HL +V      N M+   L+I F P ++ +    L     D +   + +EL++   D+ F
Sbjct: 1235 NAYVPHLVEVCTNIVETKGLGVVGIYRIPGNKAAISELSELVNTKDFQFESCASDDRWEDVNVVSSLLKLFIRSLPDALMPA------SYYINFIEADKKFGLERIVL-LREIVESLPRHP-------------------YETMKHLIRHLCRVSGNCDVNRMEPKNLAIIFGPSIIRTPNDTLETAVKDMKHQCRIVELLVTQYDYFF 1417

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Zebrafish
Match: arhgap21a (Rho GTPase activating protein 21a [Source:ZFIN;Acc:ZDB-GENE-090918-5])

HSP 1 Score: 90.8929 bits (224), Expect = 6.307e-18
Identity = 78/307 (25.41%), Postives = 129/307 (42.02%), Query Frame = 3

Query: 1761 NPP---TELSPSPSKNIL--KQALEKIRPEKK------PNKSYEV------FTGTKADFEEFKKQLESGILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHL-NKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            +PP   TE SP  S+  L  +Q L   + E K      PNK ++        T    D   ++K +  G++    +     G  F   + + P   +N  +P+I+ +C  +VE  GL   GIYR+ GN   I  +   L NK  ++ID    +W +++ I  +LK F RKL + L     +   A        +DP    K L  +                      +H+  D  ++TL++L  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++ H DW F +
Sbjct:  344 SPPSSKTEPSPKASRQSLSIRQTLLGGKGENKATSPHSPNKEHDRKAMHKDETSPPKDKGTWRKGI-PGLMRKPFEKKPSPGVTFGVRLDDCPPAQNNRFVPLIVEVCCNLVEERGLEYTGIYRVPGNNAAISIMQEELNNKGMADIDIQDDKWKDLNVISSLLKSFFRKLPEPLF---TNERYADFIDGNRIEDPVERLKVLKRL----------------------LHELPDHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHYDWFFTE 624

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Zebrafish
Match: arhgap21a (Rho GTPase activating protein 21a [Source:ZFIN;Acc:ZDB-GENE-090918-5])

HSP 1 Score: 90.5077 bits (223), Expect = 1.090e-17
Identity = 78/307 (25.41%), Postives = 129/307 (42.02%), Query Frame = 3

Query: 1761 NPP---TELSPSPSKNIL--KQALEKIRPEKK------PNKSYEV------FTGTKADFEEFKKQLESGILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHL-NKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            +PP   TE SP  S+  L  +Q L   + E K      PNK ++        T    D   ++K +  G++    +     G  F   + + P   +N  +P+I+ +C  +VE  GL   GIYR+ GN   I  +   L NK  ++ID    +W +++ I  +LK F RKL + L     +   A        +DP    K L  +                      +H+  D  ++TL++L  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++ H DW F +
Sbjct: 1061 SPPSSKTEPSPKASRQSLSIRQTLLGGKGENKATSPHSPNKEHDRKAMHKDETSPPKDKGTWRKGI-PGLMRKPFEKKPSPGVTFGVRLDDCPPAQNNRFVPLIVEVCCNLVEERGLEYTGIYRVPGNNAAISIMQEELNNKGMADIDIQDDKWKDLNVISSLLKSFFRKLPEPLF---TNERYADFIDGNRIEDPVERLKVLKRL----------------------LHELPDHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHYDWFFTE 1341

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Zebrafish
Match: arhgap23a (Rho GTPase activating protein 23a [Source:ZFIN;Acc:ZDB-GENE-121019-1])

HSP 1 Score: 87.0409 bits (214), Expect = 1.151e-16
Identity = 54/206 (26.21%), Postives = 94/206 (45.63%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            IP I+ +C  +VE++GL   GIYR+ GN  V+ +L   LNK   +I+ +  +W +++ +  +LK F RKL + L   D  +    + +  +  D     K L                         I D  D  + TL++L+ HL  V  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H  W F +
Sbjct:  936 IPQIVEICCGLVEDMGLEYTGIYRVPGNNAVVSSLQEQLNKG-VDINITEEKWQDLNVVSSLLKSFFRKLPEPLFTDDKYNDFIDANRMENASDRLRTMKKL-------------------------IRDLPDHYFHTLKFLVGHLKTVADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHYTWFFCE 1115

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Zebrafish
Match: arhgap21b (Rho GTPase activating protein 21b [Source:ZFIN;Acc:ZDB-GENE-030131-4944])

HSP 1 Score: 86.6557 bits (213), Expect = 1.562e-16
Identity = 62/234 (26.50%), Postives = 101/234 (43.16%), Query Frame = 3

Query: 1935 DSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLN-KNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYS--CKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            D     G  F   +   P    N  +P+I+ +C K+VE+ GL   GIYR+ GN   I ++   L+ K  ++ID    +W +++ I  +LK F RKL + L   +      YS    A   +DP    K L  +                      IH+  D  ++TL++L  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++   DW F +
Sbjct: 1018 DKRPAAGVTFGVRLDNCPPAQTNKFVPLIVEVCCKLVEDRGLEYTGIYRVPGNNAAISSMQEELDTKGMTDIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNE-----KYSNFIDANRMEDPVERLKALKRL----------------------IHELPDHHYETLKFLSGHLKTVSENCEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQQYDWFFTE 1224

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Zebrafish
Match: arhgap21b (Rho GTPase activating protein 21b [Source:ZFIN;Acc:ZDB-GENE-030131-4944])

HSP 1 Score: 86.6557 bits (213), Expect = 1.577e-16
Identity = 62/234 (26.50%), Postives = 101/234 (43.16%), Query Frame = 3

Query: 1935 DSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLN-KNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYS--CKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            D     G  F   +   P    N  +P+I+ +C K+VE+ GL   GIYR+ GN   I ++   L+ K  ++ID    +W +++ I  +LK F RKL + L   +      YS    A   +DP    K L  +                      IH+  D  ++TL++L  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++   DW F +
Sbjct: 1023 DKRPAAGVTFGVRLDNCPPAQTNKFVPLIVEVCCKLVEDRGLEYTGIYRVPGNNAAISSMQEELDTKGMTDIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNE-----KYSNFIDANRMEDPVERLKALKRL----------------------IHELPDHHYETLKFLSGHLKTVSENCEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQQYDWFFTE 1229

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Xenopus
Match: arhgap21 (Rho GTPase activating protein 21 [Source:NCBI gene;Acc:100037846])

HSP 1 Score: 104.76 bits (260), Expect = 5.750e-22
Identity = 80/293 (27.30%), Postives = 126/293 (43.00%), Query Frame = 3

Query: 1770 TELSPSPSKNIL--KQALEKIRPEKK------PNKSYEVFTGTKADFEEFK-KQLESGILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            +E SP PS+  L  +Q     +PE K      P +  E    +K D    K K     I+    +    TG  F   + + P   +N  +P+I+ +C K+VE+ GL   GIYR+ GN   I ++   LNK  ++ID    +W +++ I  +LK F RKL   L   +  +      +A   +DP    KTL  +                      I D  D  ++TL+YL  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++   DW F
Sbjct: 1016 SEQSPKPSRQTLSIRQPFRATKPEGKLQSPHSPKQESERRLFSKDDISPPKDKGSWRRIMKKPFEKKPTTGGTFGVRLDDCPPAHNNKYVPLIVDVCCKLVEDRGLETTGIYRVPGNNAAISSMQEELNKGSTDIDIQDDKWRDLNVISSLLKSFFRKLPDPLFTNEKYNDF---IEANRTEDPVERLKTLKRL----------------------ILDLPDHHYETLKYLSAHLKAVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQQHDWFF 1283

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Xenopus
Match: arhgap21 (Rho GTPase activating protein 21 [Source:NCBI gene;Acc:100037846])

HSP 1 Score: 102.449 bits (254), Expect = 3.333e-21
Identity = 76/294 (25.85%), Postives = 125/294 (42.52%), Query Frame = 3

Query: 1782 PSPSKNIL--KQALEKIRPEKKPNKSYEVFTGTKADFEEFKKQLESGILPPE------------LDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            P PS+  L  +Q     +PE K            +  +E +++L + I PP+             +    TG  F   + + P   +N  +P+I+ +C K+VE+ GL   GIYR+ GN   I ++   LNK  ++ID    +W +++ I  +LK F RKL   L   +  +      +A   +DP    KTL  +                      I D  D  ++TL+YL  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++   DW F
Sbjct:  795 PKPSRQTLSIRQPFRATKPEGK-------LQSPHSPKQESERRLFNDISPPKDKGSWRRIMKKPFEKKPTTGGTFGVRLDDCPPAHNNKYVPLIVDVCCKLVEDRGLETTGIYRVPGNNAAISSMQEELNKGSTDIDIQDDKWRDLNVISSLLKSFFRKLPDPLFTNEKYNDF---IEANRTEDPVERLKTLKRL----------------------ILDLPDHHYETLKYLSAHLKAVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQQHDWFF 1056

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Xenopus
Match: arhgap21 (Rho GTPase activating protein 21 [Source:NCBI gene;Acc:100037846])

HSP 1 Score: 102.064 bits (253), Expect = 3.915e-21
Identity = 78/289 (26.99%), Postives = 123/289 (42.56%), Query Frame = 3

Query: 1782 PSPSKNIL--KQALEKIRPEKK------PNKSYEVFTGTKADFEEFK-KQLESGILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            P PS+  L  +Q     +PE K      P +  E    +K D    K K     I+    +    TG  F   + + P   +N  +P+I+ +C K+VE+ GL   GIYR+ GN   I ++   LNK  ++ID    +W +++ I  +LK F RKL   L   +  +      +A   +DP    KTL  +                      I D  D  ++TL+YL  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++   DW F
Sbjct: 1040 PKPSRQTLSIRQPFRATKPEGKLQSPHSPKQESERRLFSKDDISPPKDKGSWRRIMKKPFEKKPTTGGTFGVRLDDCPPAHNNKYVPLIVDVCCKLVEDRGLETTGIYRVPGNNAAISSMQEELNKGSTDIDIQDDKWRDLNVISSLLKSFFRKLPDPLFTNEKYNDF---IEANRTEDPVERLKTLKRL----------------------ILDLPDHHYETLKYLSAHLKAVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQQHDWFF 1303

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Xenopus
Match: arhgap21 (Rho GTPase activating protein 21 [Source:NCBI gene;Acc:100037846])

HSP 1 Score: 102.064 bits (253), Expect = 3.931e-21
Identity = 78/289 (26.99%), Postives = 123/289 (42.56%), Query Frame = 3

Query: 1782 PSPSKNIL--KQALEKIRPEKK------PNKSYEVFTGTKADFEEFK-KQLESGILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            P PS+  L  +Q     +PE K      P +  E    +K D    K K     I+    +    TG  F   + + P   +N  +P+I+ +C K+VE+ GL   GIYR+ GN   I ++   LNK  ++ID    +W +++ I  +LK F RKL   L   +  +      +A   +DP    KTL  +                      I D  D  ++TL+YL  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++   DW F
Sbjct: 1066 PKPSRQTLSIRQPFRATKPEGKLQSPHSPKQESERRLFSKDDISPPKDKGSWRRIMKKPFEKKPTTGGTFGVRLDDCPPAHNNKYVPLIVDVCCKLVEDRGLETTGIYRVPGNNAAISSMQEELNKGSTDIDIQDDKWRDLNVISSLLKSFFRKLPDPLFTNEKYNDF---IEANRTEDPVERLKTLKRL----------------------ILDLPDHHYETLKYLSAHLKAVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQQHDWFF 1329

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Xenopus
Match: arhgap21 (Rho GTPase activating protein 21 [Source:NCBI gene;Acc:100037846])

HSP 1 Score: 102.064 bits (253), Expect = 3.935e-21
Identity = 78/289 (26.99%), Postives = 123/289 (42.56%), Query Frame = 3

Query: 1782 PSPSKNIL--KQALEKIRPEKK------PNKSYEVFTGTKADFEEFK-KQLESGILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            P PS+  L  +Q     +PE K      P +  E    +K D    K K     I+    +    TG  F   + + P   +N  +P+I+ +C K+VE+ GL   GIYR+ GN   I ++   LNK  ++ID    +W +++ I  +LK F RKL   L   +  +      +A   +DP    KTL  +                      I D  D  ++TL+YL  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++   DW F
Sbjct: 1018 PKPSRQTLSIRQPFRATKPEGKLQSPHSPKQESERRLFSKDDISPPKDKGSWRRIMKKPFEKKPTTGGTFGVRLDDCPPAHNNKYVPLIVDVCCKLVEDRGLETTGIYRVPGNNAAISSMQEELNKGSTDIDIQDDKWRDLNVISSLLKSFFRKLPDPLFTNEKYNDF---IEANRTEDPVERLKTLKRL----------------------ILDLPDHHYETLKYLSAHLKAVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQQHDWFF 1281

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Mouse
Match: Arhgap23 (Rho GTPase activating protein 23 [Source:MGI Symbol;Acc:MGI:3697726])

HSP 1 Score: 104.76 bits (260), Expect = 1.674e-22
Identity = 61/231 (26.41%), Postives = 105/231 (45.45%), Query Frame = 3

Query: 1962 FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDP-KSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRV 2651
            F   + E      N ++P+I+  C +IVE  GL   GIYR+ GN  V+ +L   LN+ PS+I+     W +++ I  +LK F RKL + L   D  +    + +  D  +  K+L K + D+  H                           ++TL++L+ HL  +  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H DW F D     +R 
Sbjct:  393 FGIRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDINLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDLPGHY--------------------------YETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFSDDEDKGERT 597

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Mouse
Match: Arhgap23 (Rho GTPase activating protein 23 [Source:MGI Symbol;Acc:MGI:3697726])

HSP 1 Score: 104.76 bits (260), Expect = 3.701e-22
Identity = 60/223 (26.91%), Postives = 103/223 (46.19%), Query Frame = 3

Query: 1962 FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDP-KSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            F   + E      N ++P+I+  C +IVE  GL   GIYR+ GN  V+ +L   LN+ PS+I+     W +++ I  +LK F RKL + L   D  +    + +  D  +  K+L K + D+  H                           ++TL++L+ HL  +  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H DW F D
Sbjct:  693 FGIRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDINLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDLPGHY--------------------------YETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFSD 889

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Mouse
Match: Arhgap23 (Rho GTPase activating protein 23 [Source:MGI Symbol;Acc:MGI:3697726])

HSP 1 Score: 104.375 bits (259), Expect = 5.322e-22
Identity = 60/223 (26.91%), Postives = 103/223 (46.19%), Query Frame = 3

Query: 1962 FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDP-KSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            F   + E      N ++P+I+  C +IVE  GL   GIYR+ GN  V+ +L   LN+ PS+I+     W +++ I  +LK F RKL + L   D  +    + +  D  +  K+L K + D+  H                           ++TL++L+ HL  +  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H DW F D
Sbjct:  904 FGIRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDINLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDLPGHY--------------------------YETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFSD 1100

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Mouse
Match: Arhgap21 (Rho GTPase activating protein 21 [Source:MGI Symbol;Acc:MGI:1918685])

HSP 1 Score: 100.908 bits (250), Expect = 6.457e-21
Identity = 66/226 (29.20%), Postives = 104/226 (46.02%), Query Frame = 3

Query: 1950 TGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            TGT F   + + P    N  IP+I+ +C K+VE  GL   GIYR+ GN   I ++   LNK  ++ID    +W +++ I  +LK F RKL + L   D     A   +A   +DP    +TL  +                      IHD  +  ++TL++L  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++ H DW F +
Sbjct: 1146 TGT-FGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTND---KYADFIEANRKEDPLDRLRTLKRL----------------------IHDLPEHHFETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDWFFTE 1345

[Close]

Query: 1950 TGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            TGT F   + + P    N  IP+I+ +C K+VE  GL   GIYR+ GN   I ++   LNK  ++ID    +W +++ I  +LK F RKL + L   D     A   +A   +DP    +TL  +                      IHD  +  ++TL++L  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++ H DW F +
Sbjct: 1146 TGT-FGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTND---KYADFIEANRKEDPLDRLRTLKRL----------------------IHDLPEHHFETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDWFFTE 1345

[Close]

BLAST of Rho GTPase-activating protein 21 vs. UniProt/SwissProt
Match: sp|Q69ZH9|RHG23_MOUSE (Rho GTPase-activating protein 23 OS=Mus musculus OX=10090 GN=Arhgap23 PE=1 SV=2)

HSP 1 Score: 104.375 bits (259), Expect = 3.813e-21
Identity = 60/223 (26.91%), Postives = 103/223 (46.19%), Query Frame = 3

Query: 1962 FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDP-KSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            F   + E      N ++P+I+  C +IVE  GL   GIYR+ GN  V+ +L   LN+ PS+I+     W +++ I  +LK F RKL + L   D  +    + +  D  +  K+L K + D+  H                           ++TL++L+ HL  +  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H DW F D
Sbjct:  899 FGIRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDINLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDLPGHY--------------------------YETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFSD 1095

[Close]

BLAST of Rho GTPase-activating protein 21 vs. UniProt/SwissProt
Match: sp|Q9P227|RHG23_HUMAN (Rho GTPase-activating protein 23 OS=Homo sapiens OX=9606 GN=ARHGAP23 PE=1 SV=2)

HSP 1 Score: 103.219 bits (256), Expect = 7.798e-21
Identity = 59/231 (25.54%), Postives = 104/231 (45.02%), Query Frame = 3

Query: 1962 FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDP-KSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRV 2651
            F   + E      N ++P+I+  C +IVE  GL   GIYR+ GN  V+ +L   LN+ P +I+     W +++ I  +LK F RKL + L   D  +    + +  D  +  ++L K + D+  H                           ++TL++L+ HL  +  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H DW F D     +R 
Sbjct:  903 FGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHY--------------------------YETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFSDEEDKGERT 1107

[Close]

BLAST of Rho GTPase-activating protein 21 vs. UniProt/SwissProt
Match: sp|Q5T5U3|RHG21_HUMAN (Rho GTPase-activating protein 21 OS=Homo sapiens OX=9606 GN=ARHGAP21 PE=1 SV=2)

HSP 1 Score: 102.449 bits (254), Expect = 1.528e-20
Identity = 67/226 (29.65%), Postives = 104/226 (46.02%), Query Frame = 3

Query: 1950 TGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            TGT F   + + P    N  IP+I+ +C K+VE  GL   GIYR+ GN   I ++   LNK  ++ID    +W +++ I  +LK F RKL + L   D     A   +A   +DP    KTL  +                      IHD  +  ++TL++L  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++ H DW F +
Sbjct: 1142 TGT-FGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTND---KYADFIEANRKEDPLDRLKTLKRL----------------------IHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDWFFTE 1341

[Close]

BLAST of Rho GTPase-activating protein 21 vs. UniProt/SwissProt
Match: sp|A2RUV4|RHG21_XENTR (Rho GTPase-activating protein 21 OS=Xenopus tropicalis OX=8364 GN=arhgap21 PE=2 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 2.048e-20
Identity = 78/289 (26.99%), Postives = 123/289 (42.56%), Query Frame = 3

Query: 1782 PSPSKNIL--KQALEKIRPEKK------PNKSYEVFTGTKADFEEFK-KQLESGILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            P PS+  L  +Q     +PE K      P +  E    +K D    K K     I+    +    TG  F   + + P   +N  +P+I+ +C K+VE+ GL   GIYR+ GN   I ++   LNK  ++ID    +W +++ I  +LK F RKL   L   +  +      +A   +DP    KTL  +                      I D  D  ++TL+YL  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++   DW F
Sbjct: 1069 PKPSRQTLSIRQPFRATKPEGKLQSPHSPKQESERRLFSKDDISPPKDKGSWRRIMKKPFEKKPTTGGTFGVRLDDCPPAHNNKYVPLIVDVCCKLVEDRGLETTGIYRVPGNNAAISSMQEELNKGSTDIDIQDDKWRDLNVISSLLKSFFRKLPDPLFTNEKYNDF---IEANRTEDPVERLKTLKRL----------------------ILDLPDHHYETLKYLSAHLKAVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQQHDWFF 1332

[Close]

BLAST of Rho GTPase-activating protein 21 vs. UniProt/SwissProt
Match: sp|Q6DFV3|RHG21_MOUSE (Rho GTPase-activating protein 21 OS=Mus musculus OX=10090 GN=Arhgap21 PE=1 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 4.825e-20
Identity = 66/226 (29.20%), Postives = 104/226 (46.02%), Query Frame = 3

Query: 1950 TGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            TGT F   + + P    N  IP+I+ +C K+VE  GL   GIYR+ GN   I ++   LNK  ++ID    +W +++ I  +LK F RKL + L   D     A   +A   +DP    +TL  +                      IHD  +  ++TL++L  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++ H DW F +
Sbjct: 1135 TGT-FGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTND---KYADFIEANRKEDPLDRLRTLKRL----------------------IHDLPEHHFETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDWFFTE 1334

[Close]

BLAST of Rho GTPase-activating protein 21 vs. TrEMBL
Match: A0A4Z2CWS5 (Rho GTPase-activating protein OS=Schistosoma japonicum OX=6182 GN=EWB00_006863 PE=4 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 1.464e-21
Identity = 61/216 (28.24%), Postives = 112/216 (51.85%), Query Frame = 3

Query: 1974 IHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            +H+ PR   +P +P ++ LC  +VE  GL+  GIYR+SG++     + + L+++ S ID +  +WN++HA+CG+LK FLR L  +L P  +      +C+           K L+ I+  LS  +   C           H +      TL+YL+ HL++V +    N M  + L++ F P +++  +     + +D++  IK +E ++ +  W+F
Sbjct: 1149 LHKCPRSTLSPFVPFVVELCVTLVERFGLNCIGIYRLSGSKVAHDFITSELSRDISAIDVTSDKWNDLHAVCGVLKTFLRNLPDSLFPKVMYQDFLAACRL------PQREKRLLSIQRLLSIMECYPC-----------HPEYRAHRATLRYLVTHLARVSAREGVNKMTAYNLALVFAPNLVQPCEDTPELLMSDSKYKIKLVETVIKYHAWIF 1347

[Close]

BLAST of Rho GTPase-activating protein 21 vs. TrEMBL
Match: A0A444TE12 (Rho GTPase-activating protein 21 (Fragment) OS=Armadillidium vulgare OX=13347 GN=Avbf_02030 PE=4 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 2.664e-21
Identity = 64/204 (31.37%), Postives = 104/204 (50.98%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            +P+++ LC  +VE  GLH +GIYRI GN+  +  L   +N+ P  ID S A W++V+ I  +LK F ++L   LIP+DL      + K    +DP+   + L++IR  L                    D  D  ++TL++L  HL+ VVS    N MD   L+I F P ++ +   N+  +  D     + +E+++ H +W F
Sbjct:   22 VPLLVSLCVGVVEARGLHIQGIYRIPGNRAAVTHLIETVNRGPHAIDLSDARWSDVNVISSLLKQFFQRLPDPLIPSDLYPQFIEASK---IEDPQ---QRLVEIRNLL-------------------QDLPDHHYETLKFLCLHLNHVVSNSNDNKMDVRNLAIVFGPTLVRAADDNMAKMVTDMSHQCRIVEMLISHANWFF 200

[Close]

BLAST of Rho GTPase-activating protein 21 vs. TrEMBL
Match: A0A0P4WHZ2 (Uncharacterized protein OS=Scylla olivacea OX=85551 PE=4 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 4.447e-21
Identity = 68/243 (27.98%), Postives = 114/243 (46.91%), Query Frame = 3

Query: 1893 FKKQLESGILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            F K+++SG   P    +   G      + + P+ + N  +P+++ LC  +VE+ GL  +GIYRI GN+  +  L   +NK+   ID   A W +V+ I  +LK F +KL   L  ++L     +  +A   +DPK     L  +                      IH+  D  ++TL++LL HL+ +V+   FN MD   L+I F P ++ S   N+  +  D     + +E ++ H  W F
Sbjct:  141 FMKKVQSGS--PAATPTLPEGATIGVCLEDCPQSLENEFVPLLVALCVGVVESRGLQTQGIYRIPGNKASVTYLTEMINKDAKSIDYDDARWCDVNVISSMLKQFFQKLPDPLFTSEL---YPHFIEASKVEDPKQRMLELKKL----------------------IHELPDHHYETLRFLLVHLNNIVTNSDFNKMDVRNLAIVFGPTLVRSGDDNMVTMVTDMSHQCRIVETLISHSAWFF 356

[Close]

BLAST of Rho GTPase-activating protein 21 vs. TrEMBL
Match: A0A5B7CMR4 (Rho GTPase-activating protein 21 OS=Portunus trituberculatus OX=210409 GN=arhgap21 PE=4 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 4.451e-21
Identity = 68/243 (27.98%), Postives = 113/243 (46.50%), Query Frame = 3

Query: 1893 FKKQLESGILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            F K+++SG   P    +   G      + + P+ + N  +P+++ LC  +VE+ GL  +GIYRI GN+  +  L   +NK+   ID   A W +V+ I  +LK F +KL   L   +L     +  +A   +DPK     L  +                      IH+  D  ++TL++LL HL+ +V+   FN MD   L+I F P ++ S   N+  +  D     + +E ++ H  W F
Sbjct:  115 FMKKVQSGS--PAATPTLPEGATIGVCLEDCPQSLENEFVPLLVALCVGVVESRGLQTQGIYRIPGNKASVTYLTEMINKDAKSIDYDDARWCDVNVISSMLKQFFQKLPDPLFTCEL---YPHFIEASKVEDPKQRMLELKKL----------------------IHELPDHHYETLRFLLAHLNNIVTNSDFNKMDVRNLAIVFGPTLVRSGDDNMVTMVTDMSHQCRIVETLISHSAWFF 330

[Close]

BLAST of Rho GTPase-activating protein 21 vs. TrEMBL
Match: A0A0P4W9T6 (Uncharacterized protein OS=Scylla olivacea OX=85551 PE=4 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 4.491e-21
Identity = 68/243 (27.98%), Postives = 114/243 (46.91%), Query Frame = 3

Query: 1893 FKKQLESGILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            F K+++SG   P    +   G      + + P+ + N  +P+++ LC  +VE+ GL  +GIYRI GN+  +  L   +NK+   ID   A W +V+ I  +LK F +KL   L  ++L     +  +A   +DPK     L  +                      IH+  D  ++TL++LL HL+ +V+   FN MD   L+I F P ++ S   N+  +  D     + +E ++ H  W F
Sbjct:  141 FMKKVQSG--SPAATPTLPEGATIGVCLEDCPQSLENEFVPLLVALCVGVVESRGLQTQGIYRIPGNKASVTYLTEMINKDAKSIDYDDARWCDVNVISSMLKQFFQKLPDPLFTSEL---YPHFIEASKVEDPKQRMLELKKL----------------------IHELPDHHYETLRFLLVHLNNIVTNSDFNKMDVRNLAIVFGPTLVRSGDDNMVTMVTDMSHQCRIVETLISHSAWFF 356

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Cavefish
Match: arhgap21a (Rho GTPase activating protein 21a [Source:ZFIN;Acc:ZDB-GENE-090918-5])

HSP 1 Score: 97.0561 bits (240), Expect = 8.712e-20
Identity = 85/311 (27.33%), Postives = 130/311 (41.80%), Query Frame = 3

Query: 1749 NISNNPP---TELSPSPSKNIL--KQALEKIRPEKK------PNKSYEVFTGTKADFEEFKKQLESGILPPEL-----DSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYS--CKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            N   +PP   TE SP  S+  L  +  L   + E K      PNK Y+  T  K +    K +   GI  P L     +     G  F   + + P    N  +P+I+ +C K+VE  GL   GIYR+ GN   I ++   LNK   +ID    +W +++ I  +LK F RKL + L   +      YS    A   +DP    K L  +                      +H+  D  ++TL++L  HL  V      N M+   L+I F P ++ +   N+T +        K +E ++ H DW F +
Sbjct: 1015 NTMMSPPSSKTEQSPKASRQSLSIRHTLLGGKGESKSQSPHSPNKEYDRKTIHKDESSPPKDKRRKGI--PGLMRKPFEKKASPGVTFGVRLDDCPPAHTNRFVPLIVEVCCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGVGDIDVEEDKWKDLNVISSLLKSFFRKLPEPLFTNE-----KYSDFIDANRTEDPVERLKVLKRL----------------------LHELPDHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSDDNMTHMVTHMPDQYKIVETLIQHYDWFFTE 1296

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Cavefish
Match: arhgap23a (rho GTPase-activating protein 23-like [Source:NCBI gene;Acc:103042622])

HSP 1 Score: 94.7449 bits (234), Expect = 4.251e-19
Identity = 56/206 (27.18%), Postives = 98/206 (47.57%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            IP+I+ +C  +VE +GL   GIYR+ GN  V+ +L   L+K  S+I+++   W +++ +  +LK F RKL + L   D  +    + +  +  D     KTL  +                      IHD  D  + TL++L+ HL  V  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H  W F +
Sbjct: 1016 IPLIVEICCGLVEEMGLEYTGIYRVPGNNAVVSSLQEQLDKG-SDINTAEERWQDLNVVSSLLKSFFRKLPEPLFTDDKYNDFIEANRMENASD---RLKTLKKL----------------------IHDLPDHYFHTLKFLVGHLKTVADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHYTWFFSE 1195

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Cavefish
Match: arhgap23a (rho GTPase-activating protein 23-like [Source:NCBI gene;Acc:103042622])

HSP 1 Score: 94.3597 bits (233), Expect = 4.708e-19
Identity = 56/206 (27.18%), Postives = 98/206 (47.57%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            IP+I+ +C  +VE +GL   GIYR+ GN  V+ +L   L+K  S+I+++   W +++ +  +LK F RKL + L   D  +    + +  +  D     KTL  +                      IHD  D  + TL++L+ HL  V  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H  W F +
Sbjct: 1068 IPLIVEICCGLVEEMGLEYTGIYRVPGNNAVVSSLQEQLDKG-SDINTAEERWQDLNVVSSLLKSFFRKLPEPLFTDDKYNDFIEANRMENASD---RLKTLKKL----------------------IHDLPDHYFHTLKFLVGHLKTVADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHYTWFFSE 1247

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Cavefish
Match: arhgap23a (rho GTPase-activating protein 23-like [Source:NCBI gene;Acc:103042622])

HSP 1 Score: 94.3597 bits (233), Expect = 5.224e-19
Identity = 56/206 (27.18%), Postives = 98/206 (47.57%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            IP+I+ +C  +VE +GL   GIYR+ GN  V+ +L   L+K  S+I+++   W +++ +  +LK F RKL + L   D  +    + +  +  D     KTL  +                      IHD  D  + TL++L+ HL  V  +   N M+   L++ F P ++ + + N+TD+        K +E ++ H  W F +
Sbjct: 1083 IPLIVEICCGLVEEMGLEYTGIYRVPGNNAVVSSLQEQLDKG-SDINTAEERWQDLNVVSSLLKSFFRKLPEPLFTDDKYNDFIEANRMENASD---RLKTLKKL----------------------IHDLPDHYFHTLKFLVGHLKTVADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHYTWFFSE 1262

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Cavefish
Match: arhgap23b (Rho GTPase activating protein 23b [Source:ZFIN;Acc:ZDB-GENE-081031-78])

HSP 1 Score: 87.0409 bits (214), Expect = 4.157e-17
Identity = 55/220 (25.00%), Postives = 102/220 (46.36%), Query Frame = 3

Query: 1962 FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDP-KSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWL 2618
            F   + + P   +N  +P+I+ +C  +VE +GL   GIYR+ GN  ++ TL   LNK   +I+++   W +++ I  +LK F RKL + L   D  +    + +  D  D  K++ K + D+  H                           + TL++L+ HL  V      N M+   L++ F P ++ + + N+TD+        K +E +++H  ++
Sbjct:  305 FGVRLEDCPPGANNKFVPLIVEICCGLVEQMGLEYTGIYRVPGNNAMVSTLQDQLNKG-MDINTAEERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIDANRLEDAGDRLKTMRKLIRDLPDHY--------------------------YHTLKFLIGHLKNVADNSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLILHVSFI 497

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Sea Lamprey
Match: arhgap21b (Rho GTPase activating protein 21b [Source:ZFIN;Acc:ZDB-GENE-030131-4944])

HSP 1 Score: 90.1225 bits (222), Expect = 2.149e-18
Identity = 72/296 (24.32%), Postives = 128/296 (43.24%), Query Frame = 3

Query: 1788 PSKNILKQALEKI---------RPEKKPNKSYEVFTGTKADFEE------FKKQLESGILPPELDSSDLTGTN-FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            PS  +L+Q L K          R  + P +  +   G+K D         ++K ++S +  P    S+      F   + + P  +HN  +P+I+ +C  +VE  GL   GIYR+ GN   + +L   LN+  +EID++  +W +++ I  +LK F RKL + L   +         K  +  D   +   +  ++                 +   IH+  +  + TL++L  HL  +      N M+   L+I F P ++ + + N TD+        K +E ++ H DW F D
Sbjct:  932 PSPRMLRQTLGKSTLLGPKSEQRVPRSPKQDSDRKAGSKEDLSPPKDKALWRKGIQSIMKNPFSGRSNTDAVAMFGVRLEDCPPGLHNKFLPLIVEVCCGLVEERGLESTGIYRVPGNNAAVCSLQEELNRGVTEIDTNDDKWRDLNVISSLLKSFFRKLPEPLFTDE---------KYYEFIDANRMENGVERLK----------------ALKKLIHELPEHHFHTLKFLSMHLKTIAENSPKNKMEPRNLAIVFGPTLVRTSEDN-TDMVTHMPDQYKIVETLIQHYDWFFTD 1201

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Sea Lamprey
Match: chn2 (chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5])

HSP 1 Score: 74.3294 bits (181), Expect = 5.226e-15
Identity = 58/213 (27.23%), Postives = 98/213 (46.01%), Query Frame = 3

Query: 1998 HNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKT-LMDIRYHLSSYQNSSCRKGEDKVNSDIHDQL----DCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            HN K PM++ +C K +E  GL  EG+YR+SG    I  +    +++  + D S   +++++ I G LKL+ R L   LI  D     AY         PK +  + LMD                 D+    IH+ L       +++L+YL+ HL +V  Y + N M    L+I F P +M   ++++     D       +E ++ +++ LF
Sbjct:   41 HNRKRPMVVDMCIKEIEMRGLRSEGLYRVSGFSEHIEDVKMAFDRDGEKADISANSYDDINIITGALKLYFRDLPIPLITYD-----AY---------PKFIEASKLMD----------------ADERLEGIHEALRLLPPAHYESLRYLMAHLKRVTLYSKENLMSAENLAIVFGPTLMRPPEQDVLATLNDIRYQRLVIETLINNEEILF 223

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009729.1 (pep scaffold:Pmarinus_7.0:GL479885:30406:34857:-1 gene:ENSPMAG00000008792.1 transcript:ENSPMAT00000009729.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.929 bits (154), Expect = 5.622e-12
Identity = 46/189 (24.34%), Postives = 79/189 (41.80%), Query Frame = 3

Query: 2055 GLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            GL  +GIYR+SGN   ++ L   +++       + + W ++H + G LKLF R+L ++LIP                       K   D    + +   ++C+     +   I+       +T+++L  HL +V  +R  N M    L+I F P ++ S   +      D     + LE IL     LF
Sbjct:    1 GLQVDGIYRLSGNLASVQKLRYAIDREDKLDLGTDSPWADIHVVSGALKLFFRELPESLIP----------------------QKNFGDF---VKALGMNNCQARTYAIGELINSLAGPHLETMKFLFGHLKRVAKHRDANRMSVENLAIVFGPTLLRSEMNSPQSAMNDMPHQAQVLEFILGQFSTLF 164

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Sea Lamprey
Match: chn2 (chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5])

HSP 1 Score: 62.3882 bits (150), Expect = 1.516e-10
Identity = 54/212 (25.47%), Postives = 90/212 (42.45%), Query Frame = 3

Query: 1998 HNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYS--CKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHL--SKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            H  ++PM++ +C   +E  GL  EG+YR+SG   ++  + T  +K   + D S   + +V+ I G LKL+ R+L     P  L    AY    +A    DP   ++ L  +R  L +   +                    + TL  L+ HL   +V    + N M    LSI F P +M   ++++             +EL++ H   LF
Sbjct:  121 HRGRLPMVVEMCIGEIEARGLKSEGLYRVSGVSDLVEEVRTAFDKEGEKADISAKAYEDVNVITGALKLYFREL-----PTPLVTYQAYPHFVEAAKVSDP---AERLEQLRRALQTLPPA-------------------HYDTLHCLMAHLHRRRVSQQEKHNLMSSENLSIVFGPTLMRPHEQDVLATLNGMRHQRLLVELLIRHVQELF 305

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004676.1 (pep scaffold:Pmarinus_7.0:GL476377:189826:224778:-1 gene:ENSPMAG00000004196.1 transcript:ENSPMAT00000004676.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.5438 bits (153), Expect = 1.674e-10
Identity = 47/175 (26.86%), Postives = 78/175 (44.57%), Query Frame = 3

Query: 2001 NPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVM 2525
            N  +P  + L  + V+  GL  +GIYR+SGN   I+ L   L  +  ++    + W ++H I G LK+F R+L + L P              +  DP   +  L D R  L+  +    +    K N D          T++ L +HL KV++    N M   +++I F P ++
Sbjct:  432 NTTVPKFVQLSIETVDKRGLCIDGIYRVSGNLATIQKL-RFLVDHEEKVSLDESHWEDIHVITGALKMFFRELPEPLFP-------------FNQFDPFISAIKLQDSREKLTKIKEQVQKL--PKPNKD----------TMRALFEHLKKVIACGDANRMTTQSVAIVFGPTLL 580

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Yeast
Match: RGD1 (GTPase-activating protein (RhoGAP) for Rho3p and Rho4p; possibly involved in control of actin cytoskeleton organization [Source:SGD;Acc:S000000464])

HSP 1 Score: 67.0106 bits (162), Expect = 9.522e-12
Identity = 50/208 (24.04%), Postives = 93/208 (44.71%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEW----NNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            +P I+  C  +++  GL QEGIYR S N   +  L   ++K+P+ I   L       ++++ +  +LK F   L  +++P  LS  +   C  +  +DP +    +  + Y+L                       D ++ TL+ L+ HL +V+++   N M+  AL I + P +  +   +  D+       I A+E++L   D  F
Sbjct:  485 VPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKV-C--LQIEDPTTRKNFMHGLIYNLP----------------------DAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTIAPANPDDANDV----NFQIMAMEVLLEVSDQAF 663

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Yeast
Match: RGA1 (GTPase-activating protein for polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; RGA1 has a paralog, RGA2, that arose from the whole genome duplication [Source:SGD;Acc:S000005653])

HSP 1 Score: 59.6918 bits (143), Expect = 2.521e-9
Identity = 83/320 (25.94%), Postives = 141/320 (44.06%), Query Frame = 3

Query: 1680 RFVLDLKMTTSNSFRSPSKSSTENISNNPPTELSPSPSKNILKQALEKIRPE-KKPNKSYEVF---------TGTKADFEEFKKQLESGILPPELDSSDLTGTNFNRYIHEVPRMMH-NPKIPMIIYLCTKIVEN--IGLHQEGIYRISGNQRVIRTLCTHLN----KNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLS-SYQNSSCRKGEDKVNSDIHDQLDCR-WQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVME--SWQKNLTDIKADNEIM 2576
            +F    K  T  S +  S ++T +I  + P  LS +PS       LE   P  + PN+  +V           G   D EE+            LD S+L G++       V R  + N +IPMI+ +C   +E+    +  EGIYR SG+Q VI  +    +    +  +E  + L E  +++ + G+LK +LRKL   +    +   L    K+      K + + L  +   LS   +NS           +I + L    ++ L+ L +H+ KV  Y  +N M  + L++ F P ++   S +K++ D+K  N I+
Sbjct:  702 KFFSSAKPQTEQSIQGVSTNNTNSIVKSAPVLLS-APSSGSNSGRLEISPPVLQNPNEFSDVRLVPIENDANMGQSKDGEEY------------LDGSNLYGSSL------VARCNYENNEIPMILSVCIDFIESDEENMRSEGIYRKSGSQLVIEEIEKQFSAWKVQQNTETPNILTE-QDLNVVTGVLKRYLRKLPNPIFTFQIYEPLMRLVKS------KKMMENLPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLRVLSEHIEKVTRYSHWNRMTLYNLALVFAPGLIRDFSGEKDIIDMKERNYIV 995

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Yeast
Match: BEM2 (Rho GTPase activating protein (RhoGAP); involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence; potential GAP for Rho4p [Source:SGD;Acc:S000000957])

HSP 1 Score: 54.6842 bits (130), Expect = 9.682e-8
Identity = 47/173 (27.17%), Postives = 77/173 (44.51%), Query Frame = 3

Query: 2001 NPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAE---WNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICF 2510
            N  IP I+    + +E  GL + G+YRI G+   I  L    ++  +  +S   E   W  V+AI G  K++LR+L  +L     SH +                 T + I+Y   +  N   ++    +N  +     C +QTL+ ++ HL+KV  +   N MD   L+I F
Sbjct: 1977 NTLIPTIVVKLLEEIELRGLDEVGLYRIPGSIGSINALKNAFDEEGATDNSFTLEDDRWFEVNAIAGCFKMYLRELPDSL----FSHAMVNDF-------------TDLAIKYKAHAMVNEEYKR---MMNELLQKLPTCYYQTLKRIVFHLNKVHQHVVNNKMDASNLAIVF 2129

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BLAST of Rho GTPase-activating protein 21 vs. Ensembl Yeast
Match: BEM3 (Rho GTPase activating protein (RhoGAP); involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly [Source:SGD;Acc:S000006036])

HSP 1 Score: 53.1434 bits (126), Expect = 2.640e-7
Identity = 29/87 (33.33%), Postives = 47/87 (54.02%), Query Frame = 3

Query: 2010 IPMIIYLCTK-IVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWN----------------NVHAICGILKLFLRKL 2219
            +P ++Y C + + +N G+ +EGI+R+SG+  VI+TL    +K   E D  L  +N                 V+ + G+LKL+LRKL
Sbjct:  926 LPSVVYRCLEYLYKNRGIQEEGIFRLSGSSTVIKTLQERFDK---EYDVDLCRYNESIEAKDDEASPSLYIGVNTVSGLLKLYLRKL 1009

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Yeast
Match: SAC7 (GTPase activating protein (GAP) for Rho1p; regulator of a Tor2p-mediated, Rho1p GTPase switch that controls organization of the actin cytoskeleton; negative regulator of the RHO1-PKC1-MAPK cell integrity (CWI) and membrane fluidity homeostasis signaling pathways; potential Cdc28p substrate; SAC7 has a paralog, BAG7, that arose from the whole genome duplication [Source:SGD;Acc:S000002797])

HSP 1 Score: 50.8322 bits (120), Expect = 9.845e-7
Identity = 23/82 (28.05%), Postives = 45/82 (54.88%), Query Frame = 3

Query: 2007 KIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWN--NVHAICGILKLFLRKLKQNLIPADL 2246
            +IP+++  C   ++  GL   GI+RI+GN + ++ L  ++  +P +  +   +W    VH +  +L+ +L  L + LIP  L
Sbjct:  149 RIPIVVAKCGAYLKANGLETSGIFRIAGNGKRVKAL-QYIFSSPPDYGTKFNDWETYTVHDVASLLRRYLNNLAEPLIPLSL 229

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Nematostella
Match: EDO42176 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S254])

HSP 1 Score: 76.6406 bits (187), Expect = 1.915e-14
Identity = 61/218 (27.98%), Postives = 99/218 (45.41%), Query Frame = 3

Query: 1995 MHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLC-------THLNKNPSEIDS-SLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCD-DPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            +HN K P ++ +C   VE  GL  EG+YR+SG    I  L        TH   N S+ +S +L+ +++++ I G+ KL+ R+L   LI  +       + K  D     + LSK L ++                              ++T+++L+ HL +V   R  N M E  LSI F P +M + + +  D   D +    A+EL++ HQ  LF
Sbjct:  263 LHNTKRPFVVDICINEVEKRGLDSEGLYRVSGFADDIEALKNSFDKGNTHTTVNYSDGESVNLSTYDDINTITGVCKLYFRQLPLPLITFETYSKFIAAAKTQDKHLRIEELSKALGELP--------------------------QAHYETMKFLMGHLHRVSQRRSKNMMTEENLSIVFGPTLMRAPEGDSLDSLVDMKFQRLAVELLISHQHVLF 454

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Nematostella
Match: EDO38242 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDK1])

HSP 1 Score: 71.2478 bits (173), Expect = 4.477e-14
Identity = 50/177 (28.25%), Postives = 79/177 (44.63%), Query Frame = 3

Query: 1995 MHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQL-DCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVV 2522
            +    +P+++  C   +E  GL   G+YRISGN R  + L    ++N   +D S     +++ I GILK +LR+L + LI   ++  L  + K    D      K +M                      S++   L D    TL ++L HL  V+  + FN MD   LS+C  PV+
Sbjct:   36 LEQSSVPLLVRKCVLEIEKRGLESVGLYRISGNARRKKELRGFFDENSEAVDISEENCPDINVITGILKDYLRELPEPLITEKMTEGLRKAAKNEIQDKKVDEQKQVM----------------------SELLSGLPDPNRHTLVFILNHLRHVMEKKEFNKMDARNLSVCLAPVM 190

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Nematostella
Match: EDO44981 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUA5])

HSP 1 Score: 67.781 bits (164), Expect = 2.412e-11
Identity = 54/193 (27.98%), Postives = 88/193 (45.60%), Query Frame = 3

Query: 1953 GTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMES 2531
            G  F R + E+        +P+ +  C   VE  G+  EGIYR SG    IRT+    ++   + D S  E N VHA+ G LK FL+ L + LIP +L + +  +   +D D+  ++ + L+     L             KVN          +  L+YL+ HL++V  Y + N M+   L+    P ++ +
Sbjct: 1520 GAYFGRSLQEL--CDQGKLVPLFVEKCIDFVEAEGMQIEGIYRKSGKIEDIRTIQNSFDEK-RDADFSALEMN-VHAVTGALKKFLKLLPEPLIPNNLQNNILDATVIMDADERLAVLRGLV---MQLP------------KVN----------FAVLKYLMCHLNRVTEYSKENLMESRNLATVIFPTILRT 1683

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Nematostella
Match: EDO49792 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFW5])

HSP 1 Score: 63.1586 bits (152), Expect = 5.276e-11
Identity = 27/88 (30.68%), Postives = 52/88 (59.09%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCK 2273
            +P+++ +C + ++  GL +EG++R+ GN + I TL    N+  S     L++  ++H +  +LKL+LR+L + +IP D   V   + K
Sbjct:  132 VPIVVDVCIEYIKKYGLEEEGLFRLPGNAKHISTLKAQFNRGES---PELSDEKDIHTVASLLKLYLRELSEPVIPYDFFEVFLTAAK 216

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Nematostella
Match: EDO47842 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKY9])

HSP 1 Score: 61.6178 bits (148), Expect = 1.374e-9
Identity = 48/187 (25.67%), Postives = 81/187 (43.32%), Query Frame = 3

Query: 1962 FNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLS--KTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNP 2516
            F   + EV +      IP ++      +   GL  EGI+R+SGN +V+ +L    ++   + D+ L E  +V A+ G+LKLFLR+L +  +P  L+       +    D+P  L   + L+D   +L+                         ++ L++L   L +V      N M   AL+I F P
Sbjct:  103 FGVPLEEVTKSRDGSPIPWVLAKIVHYLSQCGLKHEGIFRVSGNHKVVESLKATFDR---DGDADLEEC-DVMAVAGLLKLFLRELPEPPVPQALTTDFIKVHEVYGDDNPDCLDELRALLDKLPYLN-------------------------YELLKFLCHFLVEVSMNEENNKMSTMALAIVFGP 260

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Medaka
Match: ENSORLT00000035543.1 (rho GTPase-activating protein 23 [Source:NCBI gene;Acc:101173450])

HSP 1 Score: 100.138 bits (248), Expect = 9.150e-21
Identity = 61/209 (29.19%), Postives = 99/209 (47.37%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSD---IHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            +P+I+ +C ++VE IGL   GIYR+ GN  ++  L  HLNK    I+ +   W +++ I  +LK F RKL + L   D         K  D  D   +  T                   ED++ +    IHD  D    TL++L+ HL +V  +   N M+   L++ F P ++ + + N+TD+        K +E +++H DW F D
Sbjct:  779 VPLIVEMCCEVVETIGLEYTGIYRVPGNNAMVSNLQEHLNKG-LNINITEERWQDLNVISSLLKSFFRKLPEPLFTDD---------KYGDFIDANRIKNT-------------------EDRLKTMKKLIHDLPDYYHHTLKFLVGHLKRVADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIVHHDWFFSD 958

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Medaka
Match: ENSORLT00000032335.1 (rho GTPase-activating protein 23 [Source:NCBI gene;Acc:101173450])

HSP 1 Score: 99.3673 bits (246), Expect = 1.401e-20
Identity = 61/209 (29.19%), Postives = 99/209 (47.37%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSD---IHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            +P+I+ +C ++VE IGL   GIYR+ GN  ++  L  HLNK    I+ +   W +++ I  +LK F RKL + L   D         K  D  D   +  T                   ED++ +    IHD  D    TL++L+ HL +V  +   N M+   L++ F P ++ + + N+TD+        K +E +++H DW F D
Sbjct:  880 VPLIVEMCCEVVETIGLEYTGIYRVPGNNAMVSNLQEHLNKG-LNINITEERWQDLNVISSLLKSFFRKLPEPLFTDD---------KYGDFIDANRIKNT-------------------EDRLKTMKKLIHDLPDYYHHTLKFLVGHLKRVADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIVHHDWFFSD 1059

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Medaka
Match: ENSORLT00000036475.1 (rho GTPase-activating protein 23 [Source:NCBI gene;Acc:101173450])

HSP 1 Score: 99.3673 bits (246), Expect = 1.409e-20
Identity = 61/209 (29.19%), Postives = 99/209 (47.37%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSD---IHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            +P+I+ +C ++VE IGL   GIYR+ GN  ++  L  HLNK    I+ +   W +++ I  +LK F RKL + L   D         K  D  D   +  T                   ED++ +    IHD  D    TL++L+ HL +V  +   N M+   L++ F P ++ + + N+TD+        K +E +++H DW F D
Sbjct:  884 VPLIVEMCCEVVETIGLEYTGIYRVPGNNAMVSNLQEHLNKG-LNINITEERWQDLNVISSLLKSFFRKLPEPLFTDD---------KYGDFIDANRIKNT-------------------EDRLKTMKKLIHDLPDYYHHTLKFLVGHLKRVADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIVHHDWFFSD 1063

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Medaka
Match: ENSORLT00000045586.1 (rho GTPase-activating protein 23 [Source:NCBI gene;Acc:101173450])

HSP 1 Score: 99.3673 bits (246), Expect = 1.421e-20
Identity = 61/209 (29.19%), Postives = 99/209 (47.37%), Query Frame = 3

Query: 2010 IPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSD---IHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            +P+I+ +C ++VE IGL   GIYR+ GN  ++  L  HLNK    I+ +   W +++ I  +LK F RKL + L   D         K  D  D   +  T                   ED++ +    IHD  D    TL++L+ HL +V  +   N M+   L++ F P ++ + + N+TD+        K +E +++H DW F D
Sbjct:  897 VPLIVEMCCEVVETIGLEYTGIYRVPGNNAMVSNLQEHLNKG-LNINITEERWQDLNVISSLLKSFFRKLPEPLFTDD---------KYGDFIDANRIKNT-------------------EDRLKTMKKLIHDLPDYYHHTLKFLVGHLKRVADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIVHHDWFFSD 1076

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Medaka
Match: arhgap21a (Rho GTPase activating protein 21 [Source:NCBI gene;Acc:101172113])

HSP 1 Score: 90.8929 bits (224), Expect = 6.238e-18
Identity = 62/239 (25.94%), Postives = 104/239 (43.51%), Query Frame = 3

Query: 1914 GILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHL-NKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVD 2627
            G++    +     G  F   + + P    N  +P+I+ +C K+VE  GL   GIYR+ GN   I  +   L NK  S+ID    +W +++ I  +LK F RKL + L     +   A   +A   +DP    K L  +                      +H+  D  ++TL++L  HL  V      N M+   L+I F P ++ + + N+T +        K +E ++ + DW F +
Sbjct: 1109 GLMRKPFEKKSSAGFTFGVRLDDCPPAQTNKFVPLIVEVCCKLVEERGLEYTGIYRVPGNNSAISNMQEELNNKGVSDIDVQEDKWKDLNVISSLLKSFFRKLPEPLF---TNRRYADFIEANRIEDPVERLKVLKRL----------------------LHELPDHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTTEDNMTHMVTHMPDQYKIVETLIQNYDWFFTE 1322

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Planmine SMEST
Match: SMESG000041589.1 (SMESG000041589.1)

HSP 1 Score: 2007.65 bits (5200), Expect = 0.000e+0
Identity = 1023/1027 (99.61%), Postives = 1024/1027 (99.71%), Query Frame = 3

Query:  117 MASLKSYVIEIQKNEYRYGFDFKDEGCPYKKYAIISKVSRDVSEKHGLREGDKVIALNGEIVAGKDYVSLRNKMRKSLNNCVKLEILINRDSCGFTPEPVFQTQKDSPWEISKRILVPVGSIREKIGFFQNDGKRKIXXXXXXXXXXXXXCGCILESFNNLPEKFKRIPEXXXXXXXXXXXXXXXXDNCLKSDSNTEIYKPISQEPFFDDSIIAKCGVIEVATTSKVDRVLSHRSNEHIKNSSLISSEPVLESNPEPFESNTLLSSAVPKIEISNFHNSPSFSMSAISSKLMPVLPENISRSSTNLFEDVSIGWQGSLKSHDEFLSMTDIVTDQTKETSPSKKLIKQPSVLERIPIKLRIIQFKEKVRSKSWKDYILESTDNGARFRKRLKSLRHDKTNDFVIKSVDVKGFAAESPHKKVKTGAGIDLTSTDFSTTKYDLITNDNNVHLKFYFNPSIFQDAQSSSQAHATYNEIIGVFRPDFSKGLHINNNHCLSEPITAIHVSRSHENFSALKDLKSTDDRFVLDLKMTTSNSFRSPSKSSTENISNNPPTELSPSPSKNILKQALEKIRPEKKPNKSYEVFTGTKADFEEFKKQLESGILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRVRNTELMNNAFEYATKYIAKKYDISIRNDVSGEIASKNFDVNNLVWKIVTQATMEFGEKRRLQRRHSSHVPDQKSILPLENIENREIKRLNRNNSKVTDALDLFTSFKSVDKVPSIDENKRIKITYVSSTNSLNENDETNPPEGHVALREYNVQKRKLANCXXXXXXXXXXXXVLNHSDAFIK 3197
            MASLKSYVIEIQKNEYRYGFDFKDEGCPYKKYAIISKVSRDVSEKHGLREGDKVIALNGEIVAGKDYVSLRNKMRKSLNNCVKLEILINRDSCGFTPEPVFQTQKDSPWEISKRILVPVGSIREKIGFFQNDGKRKIVNRNNVRRSRSSSCGCILESFNNLPEKFKRIPEQMNSSSLSSMINLLQNDNCLKSDSNTEIYKPISQEPFFDDSIIAKCGVIEVA TSKVDRVLSHRSNEHIKNSSLISSEPVLESNPEPFESNTLLSSAVPKIEISNFHNSPSFSMSAISSKLMPVLPENISRSSTNLFEDVSIGWQGSLKSHDEFLSMTDIVT QTKETSPSKKLIKQPSVLERIPIKLRIIQFKEKVRSKSWKDYILESTDNGARFRKRLKSLRHDKTNDFVIKSVDVKGFAAESPHKKVK GAGIDLTSTDFSTTKYDLITNDNNVHLKFYFNPSIFQDAQSSSQAHATYNEIIGVFRPDFSKGLHINNNHCLSEPITAIHVSRSHENFSALKDLKSTDDRFVLDLKMTTSNSFRSPSKSSTENISNNPPTELSPSPSKNILKQALEKIRPEKKPNKSYEVFTGTKADFEEFKKQLESGILPPELDSSDLTGTNFNRYIHEVPRMM+NPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRVRNTELMNNAFEYATKYIAKKYDISIRNDVSGEIASKNFDVNNLVWKIVTQATMEFGEKRRLQRRHSSHVPDQKSILPLENIENREIKRLNRNNSKVTDALDLFTSFKSVDKVPSIDENKRIKITYVSSTNSLNENDETNPPEGHVALREYNVQKRKLANCDIFSRFDDDSDDVLNHSDAFIK
Sbjct:    1 MASLKSYVIEIQKNEYRYGFDFKDEGCPYKKYAIISKVSRDVSEKHGLREGDKVIALNGEIVAGKDYVSLRNKMRKSLNNCVKLEILINRDSCGFTPEPVFQTQKDSPWEISKRILVPVGSIREKIGFFQNDGKRKIVNRNNVRRSRSSSCGCILESFNNLPEKFKRIPEQMNSSSLSSMINLLQNDNCLKSDSNTEIYKPISQEPFFDDSIIAKCGVIEVAATSKVDRVLSHRSNEHIKNSSLISSEPVLESNPEPFESNTLLSSAVPKIEISNFHNSPSFSMSAISSKLMPVLPENISRSSTNLFEDVSIGWQGSLKSHDEFLSMTDIVTGQTKETSPSKKLIKQPSVLERIPIKLRIIQFKEKVRSKSWKDYILESTDNGARFRKRLKSLRHDKTNDFVIKSVDVKGFAAESPHKKVKNGAGIDLTSTDFSTTKYDLITNDNNVHLKFYFNPSIFQDAQSSSQAHATYNEIIGVFRPDFSKGLHINNNHCLSEPITAIHVSRSHENFSALKDLKSTDDRFVLDLKMTTSNSFRSPSKSSTENISNNPPTELSPSPSKNILKQALEKIRPEKKPNKSYEVFTGTKADFEEFKKQLESGILPPELDSSDLTGTNFNRYIHEVPRMMYNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRVRNTELMNNAFEYATKYIAKKYDISIRNDVSGEIASKNFDVNNLVWKIVTQATMEFGEKRRLQRRHSSHVPDQKSILPLENIENREIKRLNRNNSKVTDALDLFTSFKSVDKVPSIDENKRIKITYVSSTNSLNENDETNPPEGHVALREYNVQKRKLANCDIFSRFDDDSDDVLNHSDAFIK 1027

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Planmine SMEST
Match: SMESG000066536.1 (SMESG000066536.1)

HSP 1 Score: 122.479 bits (306), Expect = 6.906e-28
Identity = 69/218 (31.65%), Postives = 115/218 (52.75%), Query Frame = 3

Query: 1974 IHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRW--QTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            +H+  R + +  IP+ + LC  I+EN G++  G+YR+SGN+  +  +C  L K  SEID    +WN++HAI G+LK F R L   L P DL   +  +C+  + D      + L+ I+  LS             +     D  + R+  +TL+YL++HLS+V S +  N M+   L++ F P +M+  Q+    +  D +  I+ +E ++ H  WLF
Sbjct:  782 LHKWQRSITSYLIPLTVELCISIIENYGMNHVGLYRVSGNKIALDYICAELRKPVSEIDVQTDKWNDLHAISGVLKSFFRNLSDGLFPKDLYSDIIGACRMHEGD----RERRLLSIQRFLS-------------IMDIAQDHPEYRYHRETLRYLMEHLSRVASRQATNKMNAKNLAVIFAPTLMKPPQETNEILVNDYKYKIQLIEALIKHHKWLF 982

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Planmine SMEST
Match: SMESG000066536.1 (SMESG000066536.1)

HSP 1 Score: 122.479 bits (306), Expect = 7.150e-28
Identity = 69/218 (31.65%), Postives = 115/218 (52.75%), Query Frame = 3

Query: 1974 IHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRW--QTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            +H+  R + +  IP+ + LC  I+EN G++  G+YR+SGN+  +  +C  L K  SEID    +WN++HAI G+LK F R L   L P DL   +  +C+  + D      + L+ I+  LS             +     D  + R+  +TL+YL++HLS+V S +  N M+   L++ F P +M+  Q+    +  D +  I+ +E ++ H  WLF
Sbjct:  783 LHKWQRSITSYLIPLTVELCISIIENYGMNHVGLYRVSGNKIALDYICAELRKPVSEIDVQTDKWNDLHAISGVLKSFFRNLSDGLFPKDLYSDIIGACRMHEGD----RERRLLSIQRFLS-------------IMDIAQDHPEYRYHRETLRYLMEHLSRVASRQATNKMNAKNLAVIFAPTLMKPPQETNEILVNDYKYKIQLIEALIKHHKWLF 983

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Planmine SMEST
Match: SMESG000066536.1 (SMESG000066536.1)

HSP 1 Score: 122.479 bits (306), Expect = 7.668e-28
Identity = 69/218 (31.65%), Postives = 115/218 (52.75%), Query Frame = 3

Query: 1974 IHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRW--QTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            +H+  R + +  IP+ + LC  I+EN G++  G+YR+SGN+  +  +C  L K  SEID    +WN++HAI G+LK F R L   L P DL   +  +C+  + D      + L+ I+  LS             +     D  + R+  +TL+YL++HLS+V S +  N M+   L++ F P +M+  Q+    +  D +  I+ +E ++ H  WLF
Sbjct:  799 LHKWQRSITSYLIPLTVELCISIIENYGMNHVGLYRVSGNKIALDYICAELRKPVSEIDVQTDKWNDLHAISGVLKSFFRNLSDGLFPKDLYSDIIGACRMHEGD----RERRLLSIQRFLS-------------IMDIAQDHPEYRYHRETLRYLMEHLSRVASRQATNKMNAKNLAVIFAPTLMKPPQETNEILVNDYKYKIQLIEALIKHHKWLF 999

[Close]

BLAST of Rho GTPase-activating protein 21 vs. Planmine SMEST
Match: SMESG000066536.1 (SMESG000066536.1)

HSP 1 Score: 122.479 bits (306), Expect = 8.356e-28
Identity = 69/218 (31.65%), Postives = 115/218 (52.75%), Query Frame = 3

Query: 1974 IHEVPRMMHNPKIPMIIYLCTKIVENIGLHQEGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRKLKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRKGEDKVNSDIHDQLDCRW--QTLQYLLKHLSKVVSYRRFNNMDEHALSICFNPVVMESWQKNLTDIKADNEIMIKALELILIHQDWLF 2621
            +H+  R + +  IP+ + LC  I+EN G++  G+YR+SGN+  +  +C  L K  SEID    +WN++HAI G+LK F R L   L P DL   +  +C+  + D      + L+ I+  LS             +     D  + R+  +TL+YL++HLS+V S +  N M+   L++ F P +M+  Q+    +  D +  I+ +E ++ H  WLF
Sbjct:  799 LHKWQRSITSYLIPLTVELCISIIENYGMNHVGLYRVSGNKIALDYICAELRKPVSEIDVQTDKWNDLHAISGVLKSFFRNLSDGLFPKDLYSDIIGACRMHEGD----RERRLLSIQRFLS-------------IMDIAQDHPEYRYHRETLRYLMEHLSRVASRQATNKMNAKNLAVIFAPTLMKPPQETNEILVNDYKYKIQLIEALIKHHKWLF 999

The following BLAST results are available for this feature:

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Human
BLAST of Rho GTPase-activating protein 21 vs. Ensembl Celegans
BLAST of Rho GTPase-activating protein 21 vs. Ensembl Fly
BLAST of Rho GTPase-activating protein 21 vs. Ensembl Zebrafish
BLAST of Rho GTPase-activating protein 21 vs. Ensembl Xenopus
BLAST of Rho GTPase-activating protein 21 vs. Ensembl Mouse
BLAST of Rho GTPase-activating protein 21 vs. UniProt/SwissProt
BLAST of Rho GTPase-activating protein 21 vs. TrEMBL
BLAST of Rho GTPase-activating protein 21 vs. Ensembl Cavefish
BLAST of Rho GTPase-activating protein 21 vs. Ensembl Sea Lamprey
BLAST of Rho GTPase-activating protein 21 vs. Ensembl Yeast
BLAST of Rho GTPase-activating protein 21 vs. Ensembl Nematostella
BLAST of Rho GTPase-activating protein 21 vs. Ensembl Medaka
BLAST of Rho GTPase-activating protein 21 vs. Planmine SMEST

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ARHGAP23	1.624e-21	25.54	Rho GTPase activating protein 23 [Source:HGNC Symb...	[more]
ARHGAP23	1.624e-21	25.54	Rho GTPase activating protein 23 [Source:HGNC Symb...	[more]
ARHGAP21	1.683e-21	29.65	Rho GTPase activating protein 21 [Source:HGNC Symb...	[more]
ARHGAP23	1.955e-21	25.54	Rho GTPase activating protein 23 [Source:HGNC Symb...	[more]
ARHGAP23	1.955e-21	25.54	Rho GTPase activating protein 23 [Source:HGNC Symb...	[more]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tag-325	7.648e-13	25.66	WW domain-containing protein tag-325 [Source:UniP...	[more]
pac-1	3.037e-12	24.25	GTPase-activating protein pac-1 [Source:UniProtKB...	[more]
pac-1	5.135e-12	24.09	GTPase-activating protein pac-1 [Source:UniProtKB...	[more]
pac-1	5.239e-12	24.09	GTPase-activating protein pac-1 [Source:UniProtKB...	[more]
chin-1	5.324e-12	30.48	CHImaeriN (Rac-GTPase-activating protein) homolog ...	[more]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RhoGAP5A	2.262e-14	31.35	gene:FBgn0029778 transcript:FBtr0070785	[more]
RhoGAP19D	2.292e-14	25.36	gene:FBgn0031118 transcript:FBtr0301537	[more]
RhoGAP19D	2.297e-14	25.36	gene:FBgn0031118 transcript:FBtr0345015	[more]
RhoGAP19D	2.297e-14	25.36	gene:FBgn0031118 transcript:FBtr0304906	[more]
RhoGAP19D	2.473e-14	25.36	gene:FBgn0031118 transcript:FBtr0340405	[more]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
arhgap21a	6.307e-18	25.41	Rho GTPase activating protein 21a [Source:ZFIN;Acc...	[more]
arhgap21a	1.090e-17	25.41	Rho GTPase activating protein 21a [Source:ZFIN;Acc...	[more]
arhgap23a	1.151e-16	26.21	Rho GTPase activating protein 23a [Source:ZFIN;Acc...	[more]
arhgap21b	1.562e-16	26.50	Rho GTPase activating protein 21b [Source:ZFIN;Acc...	[more]
arhgap21b	1.577e-16	26.50	Rho GTPase activating protein 21b [Source:ZFIN;Acc...	[more]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
arhgap21	5.750e-22	27.30	Rho GTPase activating protein 21 [Source:NCBI gene...	[more]
arhgap21	3.333e-21	25.85	Rho GTPase activating protein 21 [Source:NCBI gene...	[more]
arhgap21	3.915e-21	26.99	Rho GTPase activating protein 21 [Source:NCBI gene...	[more]
arhgap21	3.931e-21	26.99	Rho GTPase activating protein 21 [Source:NCBI gene...	[more]
arhgap21	3.935e-21	26.99	Rho GTPase activating protein 21 [Source:NCBI gene...	[more]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Arhgap23	1.674e-22	26.41	Rho GTPase activating protein 23 [Source:MGI Symbo...	[more]
Arhgap23	3.701e-22	26.91	Rho GTPase activating protein 23 [Source:MGI Symbo...	[more]
Arhgap23	5.322e-22	26.91	Rho GTPase activating protein 23 [Source:MGI Symbo...	[more]
Arhgap21	6.457e-21	29.20	Rho GTPase activating protein 21 [Source:MGI Symbo...	[more]
Arhgap21	6.457e-21	29.20	Rho GTPase activating protein 21 [Source:MGI Symbo...	[more]

BLAST of Rho GTPase-activating protein 21 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q69ZH9\|RHG23_MOUSE	3.813e-21	26.91	Rho GTPase-activating protein 23 OS=Mus musculus O...	[more]
sp\|Q9P227\|RHG23_HUMAN	7.798e-21	25.54	Rho GTPase-activating protein 23 OS=Homo sapiens O...	[more]
sp\|Q5T5U3\|RHG21_HUMAN	1.528e-20	29.65	Rho GTPase-activating protein 21 OS=Homo sapiens O...	[more]
sp\|A2RUV4\|RHG21_XENTR	2.048e-20	26.99	Rho GTPase-activating protein 21 OS=Xenopus tropic...	[more]
sp\|Q6DFV3\|RHG21_MOUSE	4.825e-20	29.20	Rho GTPase-activating protein 21 OS=Mus musculus O...	[more]

BLAST of Rho GTPase-activating protein 21 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4Z2CWS5	1.464e-21	28.24	Rho GTPase-activating protein OS=Schistosoma japon...	[more]
A0A444TE12	2.664e-21	31.37	Rho GTPase-activating protein 21 (Fragment) OS=Arm...	[more]
A0A0P4WHZ2	4.447e-21	27.98	Uncharacterized protein OS=Scylla olivacea OX=8555...	[more]
A0A5B7CMR4	4.451e-21	27.98	Rho GTPase-activating protein 21 OS=Portunus tritu...	[more]
A0A0P4W9T6	4.491e-21	27.98	Uncharacterized protein OS=Scylla olivacea OX=8555...	[more]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
arhgap21a	8.712e-20	27.33	Rho GTPase activating protein 21a [Source:ZFIN;Acc...	[more]
arhgap23a	4.251e-19	27.18	rho GTPase-activating protein 23-like [Source:NCBI...	[more]
arhgap23a	4.708e-19	27.18	rho GTPase-activating protein 23-like [Source:NCBI...	[more]
arhgap23a	5.224e-19	27.18	rho GTPase-activating protein 23-like [Source:NCBI...	[more]
arhgap23b	4.157e-17	25.00	Rho GTPase activating protein 23b [Source:ZFIN;Acc...	[more]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
arhgap21b	2.149e-18	24.32	Rho GTPase activating protein 21b [Source:ZFIN;Acc...	[more]
chn2	5.226e-15	27.23	chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5]	[more]
ENSPMAT00000009729.1	5.622e-12	24.34	pep scaffold:Pmarinus_7.0:GL479885:30406:34857:-1 ...	[more]
chn2	1.516e-10	25.47	chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5]	[more]
ENSPMAT00000004676.1	1.674e-10	26.86	pep scaffold:Pmarinus_7.0:GL476377:189826:224778:-...	[more]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
RGD1	9.522e-12	24.04	GTPase-activating protein (RhoGAP) for Rho3p and R...	[more]
RGA1	2.521e-9	25.94	GTPase-activating protein for polarity-establishme...	[more]
BEM2	9.682e-8	27.17	Rho GTPase activating protein (RhoGAP); involved i...	[more]
BEM3	2.640e-7	33.33	Rho GTPase activating protein (RhoGAP); involved i...	[more]
SAC7	9.845e-7	28.05	GTPase activating protein (GAP) for Rho1p; regulat...	[more]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO42176	1.915e-14	27.98	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38242	4.477e-14	28.25	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44981	2.412e-11	27.98	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49792	5.276e-11	30.68	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47842	1.374e-9	25.67	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Rho GTPase-activating protein 21 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000035543.1	9.150e-21	29.19	rho GTPase-activating protein 23 [Source:NCBI gene...	[more]
ENSORLT00000032335.1	1.401e-20	29.19	rho GTPase-activating protein 23 [Source:NCBI gene...	[more]
ENSORLT00000036475.1	1.409e-20	29.19	rho GTPase-activating protein 23 [Source:NCBI gene...	[more]
ENSORLT00000045586.1	1.421e-20	29.19	rho GTPase-activating protein 23 [Source:NCBI gene...	[more]
arhgap21a	6.238e-18	25.94	Rho GTPase activating protein 21 [Source:NCBI gene...	[more]

BLAST of Rho GTPase-activating protein 21 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000041589.1	0.000e+0	99.61	SMESG000041589.1	[more]
SMESG000066536.1	6.906e-28	31.65	SMESG000066536.1	[more]
SMESG000066536.1	7.150e-28	31.65	SMESG000066536.1	[more]
SMESG000066536.1	7.668e-28	31.65	SMESG000066536.1	[more]
SMESG000066536.1	8.356e-28	31.65	SMESG000066536.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30004269 ID=SMED30004269|Name=Rho GTPase-activating protein 21|organism=Schmidtea mediterranea sexual|type=transcript|length=3335bp
TTTGTAATTGCTTATTTTGTTCTTTATGATAGATAATGTTGTTAACTACA
ATTTATAATGGCTAATAAAATGTGAATAGCGTAATATAGTAAATTTTCGA
ACCAATACTCACAAAAATGGCATCTTTGAAATCTTACGTAATTGAAATTC
AAAAAAATGAATATAGATATGGTTTTGATTTTAAAGATGAAGGTTGCCCT
TATAAAAAATATGCAATCATTTCAAAAGTAAGCAGAGATGTTTCTGAAAA
GCACGGACTCAGAGAAGGTGATAAAGTTATTGCTTTGAATGGTGAAATTG
TAGCAGGAAAAGATTATGTTTCCTTGCGTAATAAAATGCGAAAGTCTTTG
AATAATTGTGTGAAATTGGAAATACTCATTAATCGTGATTCTTGTGGTTT
TACTCCGGAACCGGTCTTCCAAACTCAGAAAGATTCACCGTGGGAGATCT
CAAAAAGGATTTTAGTCCCTGTTGGTAGTATTCGAGAGAAAATTGGATTC
TTTCAAAATGATGGCAAGAGAAAAATTGTCAATCGAAACAATGTCCGACG
ATCTCGTTCGAGCAGCTGTGGATGTATACTTGAAAGTTTCAATAATCTCC
CAGAGAAATTCAAAAGAATTCCAGAACAAATGAACTCGTCTTCATTGTCT
TCAATGATTAATTTATTGCAAAATGACAACTGTTTAAAATCTGATTCGAA
TACTGAAATTTACAAGCCCATTTCTCAAGAACCGTTCTTTGATGATTCGA
TCATAGCAAAGTGCGGTGTAATTGAAGTTGCTACTACTAGCAAAGTTGAT
CGAGTTCTCAGTCATCGATCAAATGAACATATCAAAAATTCGTCACTCAT
TTCTTCAGAACCAGTTCTAGAAAGCAATCCAGAACCTTTCGAAAGTAATA
CTCTTTTGAGTTCGGCGGTACCGAAAATCGAGATTTCAAATTTTCATAAC
AGTCCTAGTTTTTCCATGTCTGCTATTTCCTCGAAATTGATGCCGGTGCT
TCCGGAGAACATTTCTCGCAGTTCAACTAATCTTTTCGAAGATGTCTCAA
TTGGTTGGCAAGGCAGCTTAAAATCCCATGACGAATTTTTGTCCATGACT
GATATCGTCACAGACCAAACAAAAGAAACTTCGCCTAGCAAAAAGTTAAT
CAAACAGCCATCTGTTTTGGAAAGGATTCCGATCAAACTAAGAATTATTC
AATTCAAGGAAAAGGTTCGTTCTAAAAGTTGGAAAGATTATATTTTGGAG
AGTACTGATAATGGTGCTCGGTTTCGAAAACGTTTAAAAAGCCTTCGTCA
TGATAAAACCAACGATTTTGTAATTAAATCTGTTGACGTTAAAGGATTTG
CAGCGGAAAGTCCGCATAAGAAAGTTAAAACTGGTGCCGGAATTGATTTA
ACATCAACCGACTTTAGTACTACCAAATATGATTTGATTACCAACGACAA
TAATGTTCATTTGAAATTTTATTTTAATCCCAGTATCTTTCAAGATGCAC
AGTCTTCCTCACAGGCTCATGCCACTTATAATGAGATTATCGGCGTTTTC
AGGCCAGATTTTAGTAAAGGTTTGCATATAAATAATAATCATTGTCTTTC
TGAACCGATTACAGCTATACATGTATCTCGCAGCCATGAAAACTTTTCTG
CACTCAAAGACTTAAAATCCACTGATGATCGTTTTGTGCTTGATTTGAAA
ATGACGACTTCCAATTCATTTAGATCCCCTTCAAAATCATCAACAGAAAA
TATATCAAATAATCCTCCAACCGAATTAAGTCCTTCTCCCTCAAAAAATA
TTCTCAAGCAGGCACTTGAGAAAATCCGACCCGAAAAAAAACCGAATAAA
TCCTACGAAGTATTCACTGGTACAAAGGCAGATTTTGAAGAATTCAAAAA
ACAACTGGAAAGTGGAATATTACCACCGGAACTGGATTCTTCAGACTTGA
CCGGAACCAATTTTAATAGATATATTCATGAAGTTCCTCGAATGATGCAT
AATCCGAAAATACCGATGATAATTTACCTTTGTACAAAAATTGTGGAAAA
TATTGGTCTGCACCAGGAAGGGATTTATCGGATATCTGGAAATCAAAGAG
TAATTCGCACTCTATGCACCCATTTAAACAAAAATCCCAGTGAAATCGAC
TCGAGTCTTGCAGAATGGAATAATGTACACGCAATCTGTGGGATTCTGAA
GTTATTCCTGCGAAAATTGAAACAAAACCTGATACCGGCGGATCTTAGTC
ATGTTTTGGCATATTCTTGCAAAGCTGTTGATTGTGATGACCCAAAATCT
TTATCGAAAACTCTAATGGATATCAGATATCATTTATCATCTTACCAAAA
TTCCTCTTGTCGTAAAGGTGAAGACAAAGTAAACAGCGATATTCACGACC
AACTAGACTGCCGATGGCAAACTCTTCAGTATTTATTAAAGCACTTATCG
AAGGTCGTATCATATCGACGGTTTAACAACATGGATGAACATGCGTTATC
TATTTGTTTTAATCCAGTCGTAATGGAATCTTGGCAGAAAAACCTCACGG
ATATCAAGGCAGATAATGAAATTATGATTAAAGCATTAGAACTGATTCTT
ATTCATCAAGACTGGCTTTTTGTCGACTGGAACACTCACAGTGACAGAGT
TAGGAATACCGAATTGATGAATAACGCATTTGAGTACGCTACGAAATACA
TTGCCAAGAAGTATGACATTTCGATCCGGAACGATGTTTCCGGGGAAATC
GCTTCCAAAAACTTTGATGTGAATAATTTGGTTTGGAAAATTGTCACGCA
AGCTACTATGGAATTTGGTGAAAAGAGAAGACTGCAGAGGAGGCATTCAT
CTCACGTGCCTGATCAGAAATCTATTCTTCCACTTGAAAATATTGAAAAC
CGAGAAATAAAAAGATTGAACCGAAACAATTCCAAAGTTACTGATGCTTT
GGATCTATTCACGTCATTCAAATCCGTTGACAAAGTGCCTAGTATTGATG
AAAATAAACGCATCAAAATTACCTACGTTTCTTCCACAAATTCCTTGAAT
GAAAACGATGAAACTAACCCCCCTGAAGGTCACGTGGCTTTGCGGGAGTA
CAATGTTCAGAAACGGAAACTTGCTAATTGTGATATTTTTTCTAGATTTG
ATGATGATTCTGATGATGTTTTAAATCATTCAGACGCTTTTATTAAATAG
CTTCAAGGGGTATATTTGATTTGTATAGAATCGCTGCTATTACACAATTT
TGAAACTGATTTTTCAATTGAATTACTTTTTATCATTCAAAATTGAATTG
TTAAGCATATTTTTTCATAATACATATTCGATTTG

protein sequence of SMED30004269-orf-1

>SMED30004269-orf-1 ID=SMED30004269-orf-1|Name=SMED30004269-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1028bp
MASLKSYVIEIQKNEYRYGFDFKDEGCPYKKYAIISKVSRDVSEKHGLRE
GDKVIALNGEIVAGKDYVSLRNKMRKSLNNCVKLEILINRDSCGFTPEPV
FQTQKDSPWEISKRILVPVGSIREKIGFFQNDGKRKIVNRNNVRRSRSSS
CGCILESFNNLPEKFKRIPEQMNSSSLSSMINLLQNDNCLKSDSNTEIYK
PISQEPFFDDSIIAKCGVIEVATTSKVDRVLSHRSNEHIKNSSLISSEPV
LESNPEPFESNTLLSSAVPKIEISNFHNSPSFSMSAISSKLMPVLPENIS
RSSTNLFEDVSIGWQGSLKSHDEFLSMTDIVTDQTKETSPSKKLIKQPSV
LERIPIKLRIIQFKEKVRSKSWKDYILESTDNGARFRKRLKSLRHDKTND
FVIKSVDVKGFAAESPHKKVKTGAGIDLTSTDFSTTKYDLITNDNNVHLK
FYFNPSIFQDAQSSSQAHATYNEIIGVFRPDFSKGLHINNNHCLSEPITA
IHVSRSHENFSALKDLKSTDDRFVLDLKMTTSNSFRSPSKSSTENISNNP
PTELSPSPSKNILKQALEKIRPEKKPNKSYEVFTGTKADFEEFKKQLESG
ILPPELDSSDLTGTNFNRYIHEVPRMMHNPKIPMIIYLCTKIVENIGLHQ
EGIYRISGNQRVIRTLCTHLNKNPSEIDSSLAEWNNVHAICGILKLFLRK
LKQNLIPADLSHVLAYSCKAVDCDDPKSLSKTLMDIRYHLSSYQNSSCRK
GEDKVNSDIHDQLDCRWQTLQYLLKHLSKVVSYRRFNNMDEHALSICFNP
VVMESWQKNLTDIKADNEIMIKALELILIHQDWLFVDWNTHSDRVRNTEL
MNNAFEYATKYIAKKYDISIRNDVSGEIASKNFDVNNLVWKIVTQATMEF
GEKRRLQRRHSSHVPDQKSILPLENIENREIKRLNRNNSKVTDALDLFTS
FKSVDKVPSIDENKRIKITYVSSTNSLNENDETNPPEGHVALREYNVQKR
KLANCDIFSRFDDDSDDVLNHSDAFIK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0005096	GTPase activator activity
GO:0005515	protein binding

Vocabulary: **biological process**
Term	Definition
GO:0043547	positive regulation of GTPase activity
GO:0007165	signal transduction

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036034	PDZ_sf
IPR001478	PDZ
IPR000198	RhoGAP_dom
IPR008936	Rho_GTPase_activation_prot

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001478	PDZ domain	SMART	SM00228	pdz_new	coord: 16..92 e-value: 8.4E-5 score: 31.9
IPR000198	Rho GTPase-activating protein domain	SMART	SM00324	RhoGAP_3	coord: 630..828 e-value: 1.9E-28 score: 110.5
IPR000198	Rho GTPase-activating protein domain	PFAM	PF00620	RhoGAP	coord: 633..806 e-value: 1.6E-30 score: 105.9
IPR000198	Rho GTPase-activating protein domain	PROSITE	PS50238	RHOGAP	coord: 614..835 score: 29.328
IPR036034	PDZ superfamily	GENE3D	G3DSA:2.30.42.10		coord: 2..91 e-value: 1.0E-6 score: 30.6
IPR036034	PDZ superfamily	SUPERFAMILY	SSF50156	PDZ domain-like	coord: 6..87
IPR008936	Rho GTPase activation protein	GENE3D	G3DSA:1.10.555.10		coord: 616..844 e-value: 7.6E-38 score: 131.8
IPR008936	Rho GTPase activation protein	SUPERFAMILY	SSF48350	GTPase activation domain, GAP	coord: 628..835
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 534..559
None	No IPR available	PANTHER	PTHR23176	RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN	coord: 629..837
None	No IPR available	CDD	cd00992	PDZ_signaling	coord: 7..87 e-value: 1.52698E-6 score: 44.8651