Endoplasmic reticulum chaperone BiP
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30004217 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA5 (heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238]) HSP 1 Score: 211.846 bits (538), Expect = 3.138e-59 Identity = 172/613 (28.06%), Postives = 302/613 (49.27%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+++ +K PF+ K + I T EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + S G D +E + TRAK++EL + K + L++ +LK+SDI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ +E M ND E E+D++L+ R E+E AY ++ I ++ S D + ++++V E IEW + A+I D + KK E ++PI+ +
Sbjct: 29 TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGG-QTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSE-DKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLY 635
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA6 (heat shock protein family A (Hsp70) member 6 [Source:HGNC Symbol;Acc:HGNC:5239]) HSP 1 Score: 176.407 bits (446), Expect = 1.288e-46 Identity = 154/612 (25.16%), Postives = 284/612 (46.41%), Query Frame = 1
Query: 97 ETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYSSS---SVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPIL 1890
E +GI G Y + + + E++ N G T V F + ++ L+G AK ++ V D+ + L GR F + MK +PFR + K + + D T Y EEI + + + +K +AE++L V +TVP F++SQ + K +AGL +++ + +A +Y ++ + NVL+ D+ + ++ V+S D EV T ++ G F L ++ + +++ L K L R + + L++S +S+ GVD ITRA+++EL S+ + + L++ +L ++ I +VL+G S IPK+QK +++FF EL DEA A G + L K +++ ++L D+ + +E G + +I+R +P K+++ FT D+Q + I V EG++ + + N LG+ E P RG+ + +++NG + VTATD T ++ I R++ + E + E +D + +E + ++G LQ S ++ D + +++ E++ W AE + E+ K+ E +PI
Sbjct: 6 ELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTER-LVGDAAKSQAALNPHNTVFDA-KRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFY--PEEISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDF--YTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGS-LQEESLRDKIPEE-DRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRPIF 609
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]) HSP 1 Score: 171.014 bits (432), Expect = 9.492e-45 Identity = 155/618 (25.08%), Postives = 291/618 (47.09%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF K ++ K + Y EE+ + + T +K AE++L V + +TVP F++SQ + K +AGL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + K + R + + L++S +S+ G+D ITRA+++EL ++ T+ +EK L ++ +L +S I IVL+G S IPK+QK +++FF EL DEA A G + L K + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R++ + E + E +D + + +E A+ ++ + ++ ++ KIL + NEII W K AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPTNTVFDA-KRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYP--EEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDF--YTSITRARFEELNADLFRGTLDPVEKAL----RDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATV-EDEKLQGKINDEDKQKIL-DKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]) HSP 1 Score: 171.014 bits (432), Expect = 9.492e-45 Identity = 155/618 (25.08%), Postives = 291/618 (47.09%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF K ++ K + Y EE+ + + T +K AE++L V + +TVP F++SQ + K +AGL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + K + R + + L++S +S+ G+D ITRA+++EL ++ T+ +EK L ++ +L +S I IVL+G S IPK+QK +++FF EL DEA A G + L K + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R++ + E + E +D + + +E A+ ++ + ++ ++ KIL + NEII W K AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPTNTVFDA-KRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYP--EEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDF--YTSITRARFEELNADLFRGTLDPVEKAL----RDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATV-EDEKLQGKINDEDKQKIL-DKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]) HSP 1 Score: 171.014 bits (432), Expect = 9.492e-45 Identity = 155/618 (25.08%), Postives = 291/618 (47.09%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF K ++ K + Y EE+ + + T +K AE++L V + +TVP F++SQ + K +AGL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + K + R + + L++S +S+ G+D ITRA+++EL ++ T+ +EK L ++ +L +S I IVL+G S IPK+QK +++FF EL DEA A G + L K + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R++ + E + E +D + + +E A+ ++ + ++ ++ KIL + NEII W K AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPTNTVFDA-KRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYP--EEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDF--YTSITRARFEELNADLFRGTLDPVEKAL----RDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATV-EDEKLQGKINDEDKQKIL-DKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Match: hsp-3 (Heat shock 70 kDa protein C [Source:UniProtKB/Swiss-Prot;Acc:P27420]) HSP 1 Score: 207.223 bits (526), Expect = 5.993e-58 Identity = 168/614 (27.36%), Postives = 308/614 (50.16%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGF--DEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
TIIGI G Y + + E+I N G T V F D+ D+ LIG AK + + D+ + L GR +++ +K +PF+ K+ +K+ +++ T EE+ + +K AES+L +V + +TVP F+++Q + K +AGL +V+ + +A +Y +++ + + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + +Y + LY+K + + K+K+ + L+REV+ + L+T + T+ S+ G D +E + TRAK++EL + K + L++ +LK+ D+ +IVL+G S IPK+Q+ I+ FF E DEA A G G ++ +VL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + ++ NG + VTA D T + ++ I R++ ++ M ND E E D++++ + R E+E AY ++ I ++ D K ++E+V E I W + A +L+ KK E+ ++PI+ +
Sbjct: 34 TIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDR-LIGDAAKNQLTINPENTIFDA-KRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDN--KQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKAKRALSTQHQTKVEIESLFDGEDFSETL--TRAKFEELNMDLFRATLKPVQKVLEDSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDED-DKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLY 640
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Match: hsp-3 (Heat shock 70 kDa protein C [Source:UniProtKB/Swiss-Prot;Acc:P27420]) HSP 1 Score: 207.223 bits (526), Expect = 5.993e-58 Identity = 168/614 (27.36%), Postives = 308/614 (50.16%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGF--DEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
TIIGI G Y + + E+I N G T V F D+ D+ LIG AK + + D+ + L GR +++ +K +PF+ K+ +K+ +++ T EE+ + +K AES+L +V + +TVP F+++Q + K +AGL +V+ + +A +Y +++ + + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + +Y + LY+K + + K+K+ + L+REV+ + L+T + T+ S+ G D +E + TRAK++EL + K + L++ +LK+ D+ +IVL+G S IPK+Q+ I+ FF E DEA A G G ++ +VL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + ++ NG + VTA D T + ++ I R++ ++ M ND E E D++++ + R E+E AY ++ I ++ D K ++E+V E I W + A +L+ KK E+ ++PI+ +
Sbjct: 34 TIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDR-LIGDAAKNQLTINPENTIFDA-KRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDN--KQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKAKRALSTQHQTKVEIESLFDGEDFSETL--TRAKFEELNMDLFRATLKPVQKVLEDSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDED-DKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLY 640
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Match: hsp-3 (Heat shock 70 kDa protein C [Source:UniProtKB/Swiss-Prot;Acc:P27420]) HSP 1 Score: 207.223 bits (526), Expect = 5.993e-58 Identity = 168/614 (27.36%), Postives = 308/614 (50.16%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGF--DEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
TIIGI G Y + + E+I N G T V F D+ D+ LIG AK + + D+ + L GR +++ +K +PF+ K+ +K+ +++ T EE+ + +K AES+L +V + +TVP F+++Q + K +AGL +V+ + +A +Y +++ + + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + +Y + LY+K + + K+K+ + L+REV+ + L+T + T+ S+ G D +E + TRAK++EL + K + L++ +LK+ D+ +IVL+G S IPK+Q+ I+ FF E DEA A G G ++ +VL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + ++ NG + VTA D T + ++ I R++ ++ M ND E E D++++ + R E+E AY ++ I ++ D K ++E+V E I W + A +L+ KK E+ ++PI+ +
Sbjct: 34 TIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDR-LIGDAAKNQLTINPENTIFDA-KRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDN--KQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKAKRALSTQHQTKVEIESLFDGEDFSETL--TRAKFEELNMDLFRATLKPVQKVLEDSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDED-DKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLY 640
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Match: hsp-3 (Heat shock 70 kDa protein C [Source:UniProtKB/Swiss-Prot;Acc:P27420]) HSP 1 Score: 207.223 bits (526), Expect = 5.993e-58 Identity = 168/614 (27.36%), Postives = 308/614 (50.16%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGF--DEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
TIIGI G Y + + E+I N G T V F D+ D+ LIG AK + + D+ + L GR +++ +K +PF+ K+ +K+ +++ T EE+ + +K AES+L +V + +TVP F+++Q + K +AGL +V+ + +A +Y +++ + + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + +Y + LY+K + + K+K+ + L+REV+ + L+T + T+ S+ G D +E + TRAK++EL + K + L++ +LK+ D+ +IVL+G S IPK+Q+ I+ FF E DEA A G G ++ +VL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + ++ NG + VTA D T + ++ I R++ ++ M ND E E D++++ + R E+E AY ++ I ++ D K ++E+V E I W + A +L+ KK E+ ++PI+ +
Sbjct: 34 TIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDR-LIGDAAKNQLTINPENTIFDA-KRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDN--KQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKAKRALSTQHQTKVEIESLFDGEDFSETL--TRAKFEELNMDLFRATLKPVQKVLEDSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDED-DKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLY 640
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Match: hsp-3 (Heat shock 70 kDa protein C [Source:UniProtKB/Swiss-Prot;Acc:P27420]) HSP 1 Score: 207.223 bits (526), Expect = 5.993e-58 Identity = 168/614 (27.36%), Postives = 308/614 (50.16%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGF--DEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
TIIGI G Y + + E+I N G T V F D+ D+ LIG AK + + D+ + L GR +++ +K +PF+ K+ +K+ +++ T EE+ + +K AES+L +V + +TVP F+++Q + K +AGL +V+ + +A +Y +++ + + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + +Y + LY+K + + K+K+ + L+REV+ + L+T + T+ S+ G D +E + TRAK++EL + K + L++ +LK+ D+ +IVL+G S IPK+Q+ I+ FF E DEA A G G ++ +VL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + ++ NG + VTA D T + ++ I R++ ++ M ND E E D++++ + R E+E AY ++ I ++ D K ++E+V E I W + A +L+ KK E+ ++PI+ +
Sbjct: 34 TIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDR-LIGDAAKNQLTINPENTIFDA-KRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDN--KQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKAKRALSTQHQTKVEIESLFDGEDFSETL--TRAKFEELNMDLFRATLKPVQKVLEDSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDED-DKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLY 640
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073610) HSP 1 Score: 185.652 bits (470), Expect = 4.570e-50 Identity = 159/614 (25.90%), Postives = 303/614 (49.35%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKF-SRALEDYLLCLYQKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
T+IGI G Y + + E+I N G T V F + LIG AK ++ V D+ + L GR + + +K +PF+ KN + T+ EEI + +K +AE++L KV +TVP F+++Q + K +AGL++++ + +A +Y +++ E + NVLV D+ + ++ +++ D EV+ T+ ++ G F R ++ ++ +K + K+ + + L+REV+ + L+ S+ S G D +E + TRAK++EL + K + L++ ++ + D+ +IVL+G S IPK+Q+ +++FF E DEA A G + G+ G+ D + +VL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + +++NG + V+A D T ++++VI R+ ++ + M D E ++D++L+ + R E+E AY ++ I ++ S + L+ +++E I+W + A+ + + KK EA ++P++ +
Sbjct: 30 TVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA-KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVD--TSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETL--TRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQD-TDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKL-SDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQ 636
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0345166) HSP 1 Score: 185.652 bits (470), Expect = 4.570e-50 Identity = 159/614 (25.90%), Postives = 303/614 (49.35%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKF-SRALEDYLLCLYQKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
T+IGI G Y + + E+I N G T V F + LIG AK ++ V D+ + L GR + + +K +PF+ KN + T+ EEI + +K +AE++L KV +TVP F+++Q + K +AGL++++ + +A +Y +++ E + NVLV D+ + ++ +++ D EV+ T+ ++ G F R ++ ++ +K + K+ + + L+REV+ + L+ S+ S G D +E + TRAK++EL + K + L++ ++ + D+ +IVL+G S IPK+Q+ +++FF E DEA A G + G+ G+ D + +VL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + +++NG + V+A D T ++++VI R+ ++ + M D E ++D++L+ + R E+E AY ++ I ++ S + L+ +++E I+W + A+ + + KK EA ++P++ +
Sbjct: 30 TVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA-KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVD--TSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETL--TRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQD-TDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKL-SDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQ 636
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073609) HSP 1 Score: 185.652 bits (470), Expect = 4.570e-50 Identity = 159/614 (25.90%), Postives = 303/614 (49.35%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKF-SRALEDYLLCLYQKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
T+IGI G Y + + E+I N G T V F + LIG AK ++ V D+ + L GR + + +K +PF+ KN + T+ EEI + +K +AE++L KV +TVP F+++Q + K +AGL++++ + +A +Y +++ E + NVLV D+ + ++ +++ D EV+ T+ ++ G F R ++ ++ +K + K+ + + L+REV+ + L+ S+ S G D +E + TRAK++EL + K + L++ ++ + D+ +IVL+G S IPK+Q+ +++FF E DEA A G + G+ G+ D + +VL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + +++NG + V+A D T ++++VI R+ ++ + M D E ++D++L+ + R E+E AY ++ I ++ S + L+ +++E I+W + A+ + + KK EA ++P++ +
Sbjct: 30 TVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA-KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVD--TSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETL--TRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQD-TDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKL-SDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQ 636
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073611) HSP 1 Score: 185.652 bits (470), Expect = 4.570e-50 Identity = 159/614 (25.90%), Postives = 303/614 (49.35%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKF-SRALEDYLLCLYQKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
T+IGI G Y + + E+I N G T V F + LIG AK ++ V D+ + L GR + + +K +PF+ KN + T+ EEI + +K +AE++L KV +TVP F+++Q + K +AGL++++ + +A +Y +++ E + NVLV D+ + ++ +++ D EV+ T+ ++ G F R ++ ++ +K + K+ + + L+REV+ + L+ S+ S G D +E + TRAK++EL + K + L++ ++ + D+ +IVL+G S IPK+Q+ +++FF E DEA A G + G+ G+ D + +VL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + +++NG + V+A D T ++++VI R+ ++ + M D E ++D++L+ + R E+E AY ++ I ++ S + L+ +++E I+W + A+ + + KK EA ++P++ +
Sbjct: 30 TVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA-KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVD--TSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETL--TRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQD-TDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKL-SDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQ 636
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073608) HSP 1 Score: 185.652 bits (470), Expect = 4.570e-50 Identity = 159/614 (25.90%), Postives = 303/614 (49.35%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKF-SRALEDYLLCLYQKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
T+IGI G Y + + E+I N G T V F + LIG AK ++ V D+ + L GR + + +K +PF+ KN + T+ EEI + +K +AE++L KV +TVP F+++Q + K +AGL++++ + +A +Y +++ E + NVLV D+ + ++ +++ D EV+ T+ ++ G F R ++ ++ +K + K+ + + L+REV+ + L+ S+ S G D +E + TRAK++EL + K + L++ ++ + D+ +IVL+G S IPK+Q+ +++FF E DEA A G + G+ G+ D + +VL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + +++NG + V+A D T ++++VI R+ ++ + M D E ++D++L+ + R E+E AY ++ I ++ S + L+ +++E I+W + A+ + + KK EA ++P++ +
Sbjct: 30 TVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA-KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVD--TSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETL--TRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQD-TDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKL-SDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQ 636
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hspa5 (heat shock protein 5 [Source:NCBI gene;Acc:378848]) HSP 1 Score: 204.912 bits (520), Expect = 5.854e-57 Identity = 168/617 (27.23%), Postives = 308/617 (49.92%), Query Frame = 1
Query: 88 ETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTF-DEIVS--MKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
E+ T+IGI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+ D V +K +PF+ K + I + M ++ EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ + + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L+ + S G D +E + TRAK++EL + K + L++ +LK+ DI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G+++ + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ ++ M N+ E ++D++L+ R E+E AY ++ I ++ S D + ++++V E IEW + A++ + + KK E ++PI+ +
Sbjct: 23 ESVGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTTEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWGDSSVQQDIKYFPFKVIEKKNKPHIQLDIGSGQMKTFAP-EEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKRDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSAQHQARIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLEDSDLKKPDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEEETGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMVNEAERFADEDKKLKERIDSRNELESYAYSLKNQIGDKEKLGGKLSSE-DKEAIEKAVEEKIEWLEAHQDADLEEFQAKKKELEEVVQPIVSKLY 633
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hsc70 (heat shock cognate 70 [Source:ZFIN;Acc:ZDB-GENE-040426-1221]) HSP 1 Score: 168.703 bits (426), Expect = 3.797e-44 Identity = 149/615 (24.23%), Postives = 290/615 (47.15%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKD--DQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERI---NVKENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + S V D+ + L GR FD+ V MK +PF+ K ++ K T + EE+ + + T +K +E++L V + +TVP F++SQ + K +AGL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + K + R + + L++S +S+ G D ITRA+++EL ++ + + L++ ++ ++ I IVL+G S IPK+QK +++FF +L DEA A G D + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R+ +++ D++ E + + E + +E +A+ ++ + + +Q SP D K + + NE+I W K AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPSNTVFDA-KRLIGRRFDDPVVQSDMKHWPFKVISDGSKPKMEVEYKGEIKTFFP--EEVSSMVLTKMKEISEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKFKKDITGNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGADF--YTSITRARFEELNADLFRGTLEPVEKALRDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILTGDTSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNILGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEADQYRAEDEVQRE-KVTAKNTLESLAFNMKSTVEDDK--LQDKISPEDKKTITDKCNEVISWLDKNQTAEKDEYEHQQKELEKVCNPIITKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hsc70 (heat shock cognate 70 [Source:ZFIN;Acc:ZDB-GENE-040426-1221]) HSP 1 Score: 168.703 bits (426), Expect = 3.797e-44 Identity = 149/615 (24.23%), Postives = 290/615 (47.15%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKD--DQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERI---NVKENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + S V D+ + L GR FD+ V MK +PF+ K ++ K T + EE+ + + T +K +E++L V + +TVP F++SQ + K +AGL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + K + R + + L++S +S+ G D ITRA+++EL ++ + + L++ ++ ++ I IVL+G S IPK+QK +++FF +L DEA A G D + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R+ +++ D++ E + + E + +E +A+ ++ + + +Q SP D K + + NE+I W K AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPSNTVFDA-KRLIGRRFDDPVVQSDMKHWPFKVISDGSKPKMEVEYKGEIKTFFP--EEVSSMVLTKMKEISEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKFKKDITGNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGADF--YTSITRARFEELNADLFRGTLEPVEKALRDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILTGDTSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNILGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEADQYRAEDEVQRE-KVTAKNTLESLAFNMKSTVEDDK--LQDKISPEDKKTITDKCNEVISWLDKNQTAEKDEYEHQQKELEKVCNPIITKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hspa8 (heat shock protein 8 [Source:NCBI gene;Acc:573376]) HSP 1 Score: 163.31 bits (412), Expect = 3.009e-42 Identity = 152/618 (24.60%), Postives = 292/618 (47.25%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF N K ++ K + Y EEI + + T +K AE++L V + +TVP F++SQ + K ++GL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + + K + R + + L++S +S+ G+D ITRA+++EL ++ T+ +EK L ++ ++ ++ I IVL+G S IPK+QK ++++F EL DEA A G + L K + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R++ + E + E +D + +E A+ ++ + ++ ++ KIL + NE+I W K AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPTNTVFDA-KRLIGRRFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYP--EEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKHKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDF--YTSITRARFEELNADLFRGTLDPVEKAL----RDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDYFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSAKNGLESYAFNMKSTV-EDEKLKGKISDEDKQKIL-DKCNEVIGWLDKNQTAEREEFEHQQKELEKVCNPIITKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hspa8 (heat shock protein 8 [Source:NCBI gene;Acc:573376]) HSP 1 Score: 163.31 bits (412), Expect = 3.009e-42 Identity = 152/618 (24.60%), Postives = 292/618 (47.25%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF N K ++ K + Y EEI + + T +K AE++L V + +TVP F++SQ + K ++GL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + + K + R + + L++S +S+ G+D ITRA+++EL ++ T+ +EK L ++ ++ ++ I IVL+G S IPK+QK ++++F EL DEA A G + L K + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R++ + E + E +D + +E A+ ++ + ++ ++ KIL + NE+I W K AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPTNTVFDA-KRLIGRRFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYP--EEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKHKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDF--YTSITRARFEELNADLFRGTLDPVEKAL----RDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDYFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSAKNGLESYAFNMKSTV-EDEKLKGKISDEDKQKIL-DKCNEVIGWLDKNQTAEREEFEHQQKELEKVCNPIITKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527]) HSP 1 Score: 207.223 bits (526), Expect = 1.583e-57 Identity = 170/625 (27.20%), Postives = 305/625 (48.80%), Query Frame = 1
Query: 52 VTIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPIL 1890
++FA + E T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+++ +K PF+ + + I D EEI + +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + + S G D +E + TRAK++EL + K + L + +LK+SDI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ +E M D E E+D++L+ R E+E AY ++ I ++ S D + ++++V E IEW + ++I + + KK E ++PI+
Sbjct: 15 ASVFAADDDDKREDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDI--GDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQSRIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLDDADLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSE-DKETIEKAVEEKIEWLESHQDSDIEEFKAKKKELEEIVQPIV 632
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527]) HSP 1 Score: 207.223 bits (526), Expect = 1.641e-57 Identity = 174/639 (27.23%), Postives = 312/639 (48.83%), Query Frame = 1
Query: 25 YLNLLKFSFV-----TIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPIL 1890
++N L F+ V ++FA + E T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+++ +K PF+ + + I D EEI + +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + + S G D +E + TRAK++EL + K + L + +LK+SDI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ +E M D E E+D++L+ R E+E AY ++ I ++ S D + ++++V E IEW + ++I + + KK E ++PI+
Sbjct: 3 HMNFL-FALVLLVSASVFAADDDDKREDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDI--GDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQSRIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLDDADLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSE-DKETIEKAVEEKIEWLESHQDSDIEEFKAKKKELEEIVQPIV 633
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527]) HSP 1 Score: 206.838 bits (525), Expect = 1.840e-57 Identity = 170/625 (27.20%), Postives = 305/625 (48.80%), Query Frame = 1
Query: 52 VTIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPIL 1890
++FA + E T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+++ +K PF+ + + I D EEI + +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + + S G D +E + TRAK++EL + K + L + +LK+SDI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ +E M D E E+D++L+ R E+E AY ++ I ++ S D + ++++V E IEW + ++I + + KK E ++PI+
Sbjct: 15 ASVFAADDDDKREDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDI--GDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQSRIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLDDADLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSE-DKETIEKAVEEKIEWLESHQDSDIEEFKAKKKELEEIVQPIV 632
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527]) HSP 1 Score: 206.453 bits (524), Expect = 2.612e-57 Identity = 170/625 (27.20%), Postives = 305/625 (48.80%), Query Frame = 1
Query: 52 VTIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPIL 1890
++FA + E T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+++ +K PF+ + + I D EEI + +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + + S G D +E + TRAK++EL + K + L + +LK+SDI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ +E M D E E+D++L+ R E+E AY ++ I ++ S D + ++++V E IEW + ++I + + KK E ++PI+
Sbjct: 15 ASVFAADDDDKREDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDI--GDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQSRIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLDDADLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSE-DKETIEKAVEEKIEWLESHQDSDIEEFKAKKKELEEIVQPIV 632
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527]) HSP 1 Score: 188.734 bits (478), Expect = 2.688e-51 Identity = 157/569 (27.59%), Postives = 277/569 (48.68%), Query Frame = 1
Query: 52 VTIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHI 1722
++FA + E T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+++ +K PF+ + + I D EEI + +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + + S G D +E + TRAK++EL + K + L + +LK+SDI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ +E M D E E+D++L+ R E+E AY ++ I
Sbjct: 15 ASVFAADDDDKREDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDI--GDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQSRIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLDDADLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQI 577
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa5 (heat shock protein 5 [Source:MGI Symbol;Acc:MGI:95835]) HSP 1 Score: 211.846 bits (538), Expect = 2.083e-59 Identity = 172/613 (28.06%), Postives = 302/613 (49.27%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+++ +K PF+ K + I T EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + S G D +E + TRAK++EL + K + L++ +LK+SDI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ +E M ND E E+D++L+ R E+E AY ++ I ++ S D + ++++V E IEW + A+I D + KK E ++PI+ +
Sbjct: 30 TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGG-QTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSE-DKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLY 636
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa5 (heat shock protein 5 [Source:MGI Symbol;Acc:MGI:95835]) HSP 1 Score: 211.846 bits (538), Expect = 2.083e-59 Identity = 172/613 (28.06%), Postives = 302/613 (49.27%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+++ +K PF+ K + I T EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + S G D +E + TRAK++EL + K + L++ +LK+SDI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ +E M ND E E+D++L+ R E+E AY ++ I ++ S D + ++++V E IEW + A+I D + KK E ++PI+ +
Sbjct: 30 TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGG-QTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSE-DKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLY 636
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa8 (heat shock protein 8 [Source:MGI Symbol;Acc:MGI:105384]) HSP 1 Score: 171.014 bits (432), Expect = 6.392e-45 Identity = 155/618 (25.08%), Postives = 291/618 (47.09%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF K ++ K + Y EE+ + + T +K AE++L V + +TVP F++SQ + K +AGL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + K + R + + L++S +S+ G+D ITRA+++EL ++ T+ +EK L ++ +L +S I IVL+G S IPK+QK +++FF EL DEA A G + L K + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R++ + E + E +D + + +E A+ ++ + ++ ++ KIL + NEII W K AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPTNTVFDA-KRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYP--EEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDF--YTSITRARFEELNADLFRGTLDPVEKAL----RDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATV-EDEKLQGKINDEDKQKIL-DKCNEIISWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa2 (heat shock protein 2 [Source:MGI Symbol;Acc:MGI:96243]) HSP 1 Score: 164.851 bits (416), Expect = 7.791e-43 Identity = 154/620 (24.84%), Postives = 288/620 (46.45%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE---TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFG-KDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERIN-------VKENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
IGI G Y + + E+I N G T V F + ++ LIG AK + + I + L GR F++ MK +PFR + K ++ K +M ++ EEI + + T +K AE++L KV S +TVP F++SQ + K + GL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + +L +++ + + K + R + + L++S +S+ GVD ITRA+++EL ++ + + L++ +L + I +IVL+G S IPK+QK +++FF EL DEA A G + + G K + + ++L D+ + IE G + +I+R +P K+++ FT D+Q +++ V EG++ + + N LG+ + P RG+ + +++NG + VTA D T + ++ I R++ V+E E +DR +A K +E Y I+ +++ ++ KIL + E+I W + AE + E+ +K E PI+ +
Sbjct: 8 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYK-GEMKTFFP-EEISSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDF--YTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDR---VAAK--NAVESYTYNIK-QTVEDEKLRGKISEQDKNKIL-DKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQ 615
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa2 (heat shock protein 2 [Source:MGI Symbol;Acc:MGI:96243]) HSP 1 Score: 164.851 bits (416), Expect = 7.791e-43 Identity = 154/620 (24.84%), Postives = 288/620 (46.45%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE---TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFG-KDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERIN-------VKENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
IGI G Y + + E+I N G T V F + ++ LIG AK + + I + L GR F++ MK +PFR + K ++ K +M ++ EEI + + T +K AE++L KV S +TVP F++SQ + K + GL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + +L +++ + + K + R + + L++S +S+ GVD ITRA+++EL ++ + + L++ +L + I +IVL+G S IPK+QK +++FF EL DEA A G + + G K + + ++L D+ + IE G + +I+R +P K+++ FT D+Q +++ V EG++ + + N LG+ + P RG+ + +++NG + VTA D T + ++ I R++ V+E E +DR +A K +E Y I+ +++ ++ KIL + E+I W + AE + E+ +K E PI+ +
Sbjct: 8 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYK-GEMKTFFP-EEISSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDF--YTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDR---VAAK--NAVESYTYNIK-QTVEDEKLRGKISEQDKNKIL-DKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQ 615
BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|P06761|BIP_RAT (Endoplasmic reticulum chaperone BiP OS=Rattus norvegicus OX=10116 GN=Hspa5 PE=1 SV=1) HSP 1 Score: 214.927 bits (546), Expect = 1.078e-59 Identity = 173/613 (28.22%), Postives = 303/613 (49.43%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+++ +K PF+ K + I T EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + S G D +E + TRAK++EL + K + L++ +LK+SDI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ +E M ND E E+D++L+ R E+E AY ++ I ++ SP D + ++++V E IEW + A+I D + KK E ++PI+ +
Sbjct: 29 TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGG-QTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKL-SPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLY 635
BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q24895|BIP_ECHMU (Endoplasmic reticulum chaperone BiP OS=Echinococcus multilocularis OX=6211 GN=GRP78 PE=2 SV=1) HSP 1 Score: 213.772 bits (543), Expect = 3.003e-59 Identity = 167/641 (26.05%), Postives = 323/641 (50.39%), Query Frame = 1
Query: 16 MAVYLNLLKFSFVTIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKM-TETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
++ Y+ +T+ S G E T+IGI G Y + + E+I N G T V F + LIG AK +S+ + + L GR +D+ +K+YPF+ KN +++ + + EE+ + + +K AE++L ++V +TVP F+++Q + K +AGL +++ + +A +Y +++ + + N+LV D+ + ++ +++ D EV+ T ++ G F + L DY + LY+K + K+ + + L+REV+ + L+T + T +++ G D +E P+TRA+++EL ++ K ++ +++ LK+ DI IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G +D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N FLG+ + P RGL + ++ NG + V+A D T + +VI K R+ + E + + E +++D++++ ++R ++E +AY I+ + ++ S ++K ++++ +E I+W AE +D + K E+ ++PI+ +
Sbjct: 3 LSTYVGTFLLCILTLSHCKS--GKEEYGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSGDGERLIGDAAKNQLTSNPKNTLFDAKRLIGRDYDDKDVQGDIKRYPFKVINKNNKPYMKVQVGSEE--KGFAPEEVSAMVLSKMKEIAEAYLGTEVTHAVVTVPAYFNDAQRQATKDAGAIAGLTVLRIINEPTAAAIAYGLDKKDTEKNILVFDLGGGTFDVSLLTIDNGVFEVVATSGDTHLGGEDFDQRLIDYFVKLYKKKEGKDITKDDRAVQKLRREVEKAKRTLSTEHSTMIEIDNLFEGKDFSE--PLTRARFEELNNDLFRSTLKPVMKVMEDSGLKKEDIDDIVLVGGSTRIPKIQQLVKEFFNVKEPSRGINPDEAVAYGAAVQAGVISGVEDTGDIVLL-DVCPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPTVTIQVFEGERPMTKDNHFLGKFDLTGIPPAPRGLPQIEVTFEIDVNGILRVSAEDKGTGKKSNIVINKETNRLTPEEIERMIQDAEKFSDQDKQVKERVEVRNDLESLAYSIKNQVKDKEKMGGKL-SDDEIKTIEDAADEAIKWMENNPQAETSDYKKQKANLESVVQPIVSKLYE 635
BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q90593|BIP_CHICK (Endoplasmic reticulum chaperone BiP OS=Gallus gallus OX=9031 GN=HSPA5 PE=1 SV=1) HSP 1 Score: 213.386 bits (542), Expect = 4.145e-59 Identity = 171/613 (27.90%), Postives = 303/613 (49.43%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+++ +K PF+ K + + T EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + S G D +E + TRAK++EL + K + L++ +LK+SDI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ +E M ND E E+D++L+ R E+E AY ++ I ++ S D + ++++V E IEW + A+I D ++ KK E ++PI+ +
Sbjct: 27 TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWNDPSVQQDIKYLPFKVVEKKAKPHIQVDVGGG-QTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDARNELESYAYSLKNQIGDKEKLGGKLSSE-DKETIEKAVEEKIEWLESHQDADIEDFKSKKKELEEVVQPIVSKLY 633
BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q24798|BIP_ECHGR (Endoplasmic reticulum chaperone BiP OS=Echinococcus granulosus OX=6210 GN=GRP78 PE=2 SV=1) HSP 1 Score: 213.386 bits (542), Expect = 4.600e-59 Identity = 168/641 (26.21%), Postives = 322/641 (50.23%), Query Frame = 1
Query: 16 MAVYLNLLKFSFVTIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTF---DEIVSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKM-TETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
++ Y+ + +T+ S G E T+IGI G Y + + E+I N G T V F + LIG AK +S+ + + L GR + D +K+YPF+ KN +++ + + EE+ + + +K AE++L ++V +TVP F+++Q + K +AGL +++ + +A +Y + + + + N+LV D+ + ++ +++ D EV+ T ++ G F + L DY + LY+K + K+ + + L+REV+ + L+T + T +++ G D +E P+TRA+++EL ++ K ++ +++ LK+ DI IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G +D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N FLG+ + P RGL + ++ NG + V+A D T + +VI K RI + E + + E +++D++++ ++R ++E +AY I+ + ++ S ++K ++++ +E I+W AE +D + K E+ ++PI+ +
Sbjct: 3 LSTYVGIFLLCILTLSRCKS--GKEEYGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSGDGERLIGDAAKNQLTSNPKNTLFDAKRLIGRDYHDKDVQGDIKRYPFKVINKNNKPYMKVQVGSEE--KGFAPEEVSAMVLSKMKEIAEAYLGTEVTHAVVTVPAYFNDAQRQATKDAGAIAGLTVLRIINEPTAAAIAYGLEKKDTEKNILVFDLGGGTFDVSLLTIDNGVFEVVATSGDTHLGGEDFDQRLIDYFVKLYKKKEGKDITKDDRAVQKLRREVEKAKRTLSTEHSTMIEIDNLFEGKDFSE--PLTRARFEELNNDLFRSTLKPVMKVMEDSGLKKEDIDDIVLVGGSTRIPKIQQLVKEFFNGKEPIRGINPDEAVAYGAAVQAGVISGVEDTGDIVLL-DVCPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPTVTIQVFEGERPMTKDNHFLGKFDLTGIPPAPRGLPQIEVTFEIDVNGILRVSAEDKGTGKKSNIVINKETNRITPEEIERMIQDAEKFSDQDKQVKERVEVRNDLESLAYSIKNQVKDKEKMGGKL-SDDEIKTIEDAADEAIKWMENNPQAETSDYKKQKANLESVVQPIVSKLYE 635
BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q0VCX2|BIP_BOVIN (Endoplasmic reticulum chaperone BiP OS=Bos taurus OX=9913 GN=HSPA5 PE=2 SV=1) HSP 1 Score: 212.231 bits (539), Expect = 1.358e-58 Identity = 171/613 (27.90%), Postives = 302/613 (49.27%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+++ +K PF+ K + + T EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + S G D +E + TRAK++EL + K + L++ +LK+SDI +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ +E M ND E E+D++L+ R E+E AY ++ I ++ S D + ++++V E IEW + A+I D + KK E ++PI+ +
Sbjct: 30 TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDVGGG-QTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSE-DKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLY 636
BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A0R3TVW3 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS11970 PE=3 SV=1) HSP 1 Score: 224.557 bits (571), Expect = 1.328e-60 Identity = 174/645 (26.98%), Postives = 326/645 (50.54%), Query Frame = 1
Query: 16 MAVYLNLLKFSFVTIFAIVSNVGCETSET----IIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKM-TETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
M V+ N+L VT +I++ CE+ +T +IGI G Y + + E+I N G T V F + LIG AK +S+ + + L GRTFD+ MK+YPF+ K ++ D EE+ + +K AE++L + V +TVP F+++Q + K +AGL I++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + L DY LY+K + +K+ + + L+REV+ + L+T + T +S G D +E + TRA+++EL ++ K + + +K+ +LK+ DI IVL+G S IPK+Q+ ++ FF EL DEA A G + G+ G +D + V+L D+ + IE G + +I R ++P KKS+ F+ D Q + I V EG++ + + N FLG+ + P RG+ + ++ NG + V+A D T ++++VI K R++ + E + + E +++D++++ + R E E +AY ++ + ++ D+ ++++ + I+W + AE ++ + KK+ ++ ++PI+ +
Sbjct: 1 MGVWTNVL----VTFLSILALSRCESGKTDYGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTNTGERLIGDAAKNQLTSNPRNTLFDAKRLIGRTFDDKDVQEDMKRYPFKVIKKGDKPYMEVQ--VGDEVKAFAPEEVSAMVLGKMKEVAEAYLGTPVTHAVVTVPAYFNDAQRQATKDAGAIAGLTILRIINEPTAAAIAYGLDKKESEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRLIDYFAKLYKKKEGKDIMKDVRAVQKLRREVEKAKRTLSTEHSTVIEIDSFIDGKDFSETL--TRARFEELNNDLFRSTIKPVENVMKDSDLKKEDIHDIVLVGGSTRIPKVQELVKEFFNGKELSRGINPDEAVAYGAAVQAGVISGVEDTGDIVLL-DVCPLTLGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADDQPTVTIQVYEGERPLTKDNHFLGKFDLTGIPPAPRGIPQIEVTFEIDVNGLLQVSAEDKGTGKREKIVINKETNRLSPEEIEKMIQDAEKFSDQDKQVKERVEARNEFESLAYSVKNQVKDKKKLGDKLTEE-DINTIEKAAEDAIKWMEDHPQAETSEYKEEKKKLDSIVQPIISKLYQ 635
BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A183TPZ0 (Glucose-regulated protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS18537 PE=3 SV=1) HSP 1 Score: 221.09 bits (562), Expect = 2.036e-59 Identity = 171/612 (27.94%), Postives = 307/612 (50.16%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
T++GI G Y + + E+I N G T V F ++ LIG AK +S+ + + L GR F + +K+YPF+ KN+ + + +M ++ EEI + ++K AE++L +KV +TVP F+++Q S K ++GL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T ++ G F + DY L LY+K T + K+ + + L+REV+ + L+T + + G D +E + TRA ++EL S E K + + + +LK+SDI +IVL+G S IPK+Q+ +++FF E DEA A G G + +VL D+ + IE G + +I R ++P KK++ F+ D+Q + I V EG++L+ + N FLG+ + P RG+ + V+ NG + VTA D T + +VI K R+N +E M ND E +E+D ++ + R E+E +A+ ++ + ++ S D + ++++ E I+W K AE + ++ KK+ E ++PI+ +
Sbjct: 31 TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSTENERLIGDAAKNQLTSNPENTLFDAKRLIGREFSDPEVQADIKRYPFKVIEKNRKPYLEVNV-GGEMKAFAP-EEISAMVLGHMKQIAEAYLGTKVTHAVITVPAYFNDAQRQSTKDAGVISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLMTIDNGVFEVLATSGDTHLGGEDFDHRVIDYFLKLYKKKTGKDASKDTRAVQKLRREVEKAKRTLSTEHSVTVEVDDFFEGNDFSETL--TRALFEELNSALFRETIKPVQKVMDDSDLKKSDIDEIVLVGGSTRIPKIQQLVKDFFDGKEPSRGINPDEAVAYGAAVQAGIIGGAENTGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKAQVFSTAADNQPTVTIQVYEGERLMTKDNHFLGKFDLTGIPPAPRGVPQIEVTFEVDVNGILRVTAEDKGTGKKSNIVINKETNRLNAEEIERMINDAEKFSEQDNRVKERVEARNELEGLAFSLKTQLNDKEKLAGKL-SDSDKESVEKAAQEAIDWLEKNPQAEAQECKDQKKKLEEVVQPIMSKLYQ 637
BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A0R3U5K9 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS2014 PE=3 SV=1) HSP 1 Score: 219.55 bits (558), Expect = 6.372e-59 Identity = 170/636 (26.73%), Postives = 322/636 (50.63%), Query Frame = 1
Query: 43 FSFVTIFAIVSNV----GCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKM-TETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
F F +F +V + G E T+IGI G Y + + E+I N G T V F LIG AK +S+ + + L GR FD+ +K+YPF+ KN ++ N + EE+ + +K AE++L +KV +TVP F+++Q + K ++AGL +++ + +A +Y +++ +++ N+LV+D+ + ++ +++ D EV+ T ++ G F + L +Y + LY+K + ++ + + L+REV+ + L+T + T +S G D +E +TRA+++EL ++ K + + + LK+ DI IVL+G S IPK+Q+ ++ +F E DEA A G + G+ G +D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N FLG+ + P RG+ + ++ NG + V+A D T + ++VI K R++ +E M +D E +++D++++ + R E+E AY ++ + S ++ ++KI++ + +E I+W AE+++ + KK+ E ++PI++ +
Sbjct: 5 FVFTVLFCVVVSCKEESGKEDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTSDGDRLIGDAAKNQLTSNPRNTLFDAKRLIGRDFDDKDVQSDIKRYPFKVINKNNKPYMQAEVGDNQKKDFAP-EEVSAMVLGKMKEIAEAYLGTKVTHAVVTVPAYFNDAQRQATKDAGSIAGLTVLRIINEPTAAAIAYGLDKKDDEKNILVVDLGGGTFDVSLLTIDNGVFEVVATSGDTHLGGEDFDQRLIEYFIKLYKKKEGKDISQDHRAVQKLRREVEKAKRTLSTEHSTVIEIDSFFEGKDFSET--LTRARFEELNNDLFRSTLKPVEKVMSDSGLKKEDIDDIVLVGGSTRIPKIQQLVKEYFNGKEPSRGINPDEAVAYGAAVQAGVISGVEDTGDIVLL-DVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVSAEDKGTGKKNKIVINKETNRLSPEEIERMIHDAEKFSDQDKQVKERVEARNELESFAYSVKNQVKDKESVGGKLGDE-EVKIIEGAADEAIQWMENNPQAEVSEYKEQKKKIEEVVQPIIRKLYE 635
BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A5K3FET8 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 219.935 bits (559), Expect = 9.236e-59 Identity = 170/636 (26.73%), Postives = 322/636 (50.63%), Query Frame = 1
Query: 43 FSFVTIFAIVSNV----GCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKM-TETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
F F +F +V + G E T+IGI G Y + + E+I N G T V F LIG AK +S+ + + L GR FD+ +K+YPF+ KN ++ N + EE+ + +K AE++L +KV +TVP F+++Q + K ++AGL +++ + +A +Y +++ +++ N+LV+D+ + ++ +++ D EV+ T ++ G F + L +Y + LY+K + ++ + + L+REV+ + L+T + T +S G D +E +TRA+++EL ++ K + + + LK+ DI IVL+G S IPK+Q+ ++ +F E DEA A G + G+ G +D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N FLG+ + P RG+ + ++ NG + V+A D T + ++VI K R++ +E M +D E +++D++++ + R E+E AY ++ + S ++ ++KI++ + +E I+W AE+++ + KK+ E ++PI++ +
Sbjct: 36 FVFTVLFCVVVSCKEESGKEDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTSDGDRLIGDAAKNQLTSNPRNTLFDAKRLIGRDFDDKDVQSDIKRYPFKVINKNNKPYMQAEVGDNQKKDFAP-EEVSAMVLGKMKEIAEAYLGTKVTHAVVTVPAYFNDAQRQATKDAGSIAGLTVLRIINEPTAAAIAYGLDKKDDEKNILVVDLGGGTFDVSLLTIDNGVFEVVATSGDTHLGGEDFDQRLIEYFIKLYKKKEGKDISQDHRAVQKLRREVEKAKRTLSTEHSTVIEIDSFFEGKDFSET--LTRARFEELNNDLFRSTLKPVEKVMSDSGLKKEDIDDIVLVGGSTRIPKIQQLVKEYFNGKEPSRGINPDEAVAYGAAVQAGVISGVEDTGDIVLL-DVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVSAEDKGTGKKNKIVINKETNRLSPEEIERMIHDAEKFSDQDKQVKERVEARNELESFAYSVKNQVKDKESVGGKLGDE-EVKIIEGAADEAIQWMENNPQAEVSEYKEQKKKIEEVVQPIIRKLYE 666
BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A0R3W319 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS4273 PE=3 SV=1) HSP 1 Score: 217.238 bits (552), Expect = 5.502e-58 Identity = 168/637 (26.37%), Postives = 326/637 (51.18%), Query Frame = 1
Query: 46 SFVTIF--AIVSNVGCETSE----TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKM-TETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
++V+IF I++ C++ + T+IGI G Y + + E+I N G T V F + LIG AK +S+ + + L GR +D+ +K+YPF+ KN +++ T + EE+ + + +K AE++L + V +TVP F+++Q + K +AGL +++ + +A +Y +++ + + N+LV D+ + ++ +++ D EV+ T ++ G F + L DY + LY+K + K+ + + L+REV+ + L+T + T +++ G D +E P+TRA+++EL ++ K ++ +++ LK+ DI IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G +D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N FLG+ + P RGL + ++ NG + V+A D T + +VI K R++ + E + + E +++D++++ ++R ++E +AY I+ + ++ S ++K ++ + +E I+W AE +D + K + E+ ++PI+ +
Sbjct: 5 AYVSIFLLCILTLSHCKSGKEDYGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSGDGERLIGDAAKNQLTSNPKNTLFDAKRLIGRDYDDKDVQSDIKRYPFKVINKNNKPYMQVQVGTEE--KGFAPEEVSAMVLSKMKEIAEAYLGTAVTHAVVTVPAYFNDAQRQATKDAGAIAGLTVLRIINEPTAAAIAYGLDKKDTEKNILVFDLGGGTFDVSLLTIDNGVFEVVATSGDTHLGGEDFDQRLIDYFVKLYKKKEGKDITKDDRAVQKLRREVEKAKRTLSTEHSTMIEIDNLFEGKDFSE--PLTRARFEELNNDLFRSTLKPVMKVMEDSGLKKEDIDDIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVISGVEDTGDIVLL-DVCPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPPAPRGLPQIEVTFEIDVNGILRVSAEDKGTGKKSNIVINKETNRLSPEEIERMIQDAEKFSDQDKQVKERVEVRNDLESLAYSIKNQVKDKEKMGGKL-SEDEIKTIENAADEAIKWMENNPQAETSDYKEQKAKLESVVQPIVSKLYE 635
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: hspa5 (heat shock protein family A (Hsp70) member 5 [Source:NCBI gene;Acc:103030781]) HSP 1 Score: 205.682 bits (522), Expect = 2.786e-57 Identity = 170/641 (26.52%), Postives = 315/641 (49.14%), Query Frame = 1
Query: 43 FSFVTIFAIVSNVGC---------ETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
+ +F +V VGC E T++GI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GRT+ + +K +PF+ K + I + ++ EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ + + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L++ + S G D +E + TRAK++EL + K + L++ +LK+S+I +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G++D + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ ++ M ND E ++D++L+ R E+E AY ++ + ++ S D + ++++V E IEW + A++ + + KK E ++PI+ +
Sbjct: 1 MKILCLFMLV--VGCVYADDDDKKENVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRTWGDSSVQQDVKYFPFKVLEKKSKPHIQVDIGAGQLKTFAP-EEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSEINEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEEDTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMVNDAERFADEDKKLKERIDSRNELESYAYSLKNQVGDKEKLGGKL-SDEDKEAIEKAVEEKIEWLESHQDADLEEFQAKKKELEEVVQPIISKLY 633
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: hsc70 (heat shock cognate 71 kDa protein-like [Source:NCBI gene;Acc:103045816]) HSP 1 Score: 167.933 bits (424), Expect = 7.024e-44 Identity = 153/619 (24.72%), Postives = 296/619 (47.82%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERI---NVKENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF+ K ++ K T Y EE+ + + T +K +E++L V + +TVP F++SQ + K +AGL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + K + R + + L++S +S+ GVD ITRA+++EL S+ T+ +EK L ++ +L ++ I IVL+G S IPK+QK +++FF +L DEA A G + L K + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R+ +++ D++ E + + E + +E +A+ ++ + ++ ++ S D K + + NE+I W + AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPNNTVFDA-KRLIGRRFDDAVVQSDMKHWPFKVVSDGGKPKMEVEYKGEIKTFYP--EEVSSMVLTKMKEISEAYLGKPVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKFKKDITGNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDF--YTSITRARFEELNSDLFRGTLDPVEKAL----RDAKLDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNILGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEADQYRAEDEAQREKVTS-KNTLESLAFNMKSTV-EDEKLKDKI-SAEDKKTIVDKCNEVIAWLDRNQTAEKEEYEHQQKELEKVCNPIITKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: hspa8b (heat shock cognate 70 kDa protein-like [Source:NCBI gene;Acc:103047344]) HSP 1 Score: 165.236 bits (417), Expect = 5.390e-43 Identity = 155/618 (25.08%), Postives = 292/618 (47.25%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF + K ++ K T EEI + + +K AE++L V + +TVP F++SQ + K ++GL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + + K + R + + L++S +S+ GVD ITRA+++EL ++ T+ +EK+L ++ +L +S I IVL+G S IPK+QK +++FF EL DEA A G + L K + + ++L D+ + IE G + ++I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R++ +E M D E +D + +E A+ ++ + ++ ++ KIL + NE+I W K AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPTNTVFDA-KRLIGRRFDDAVVQSDMKHWPFTVINDSTRPKVQVEYKGE--TKAFYPEEISSMVLVKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFISEFKRKYKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDF--YTSITRARFEELNADLFRGTLDPVEKSL----RDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILAGDKSENVQDLLLLDVTPLSLGIETAGGVMTILIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEEIERMVQDAEKYKAEDDVQRDKVAAKNGLESYAFNMKSTV-EDEKLKGKISDEDKQKIL-DKCNEVISWLDKNQTAEKDEFEHQQKELEKVCNPIITKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: hspa8 (heat shock cognate 71 kDa protein [Source:NCBI gene;Acc:103043364]) HSP 1 Score: 163.31 bits (412), Expect = 2.860e-42 Identity = 150/617 (24.31%), Postives = 289/617 (46.84%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + + I + L GR FD+ V MK +PF + K + K + Y EEI + + +K AE++L V + +TVP F++SQ + K ++GL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + + K + R + + L++S +S+ GVD ITRA+++EL ++ T+ +EK+L ++ ++ ++ I IVL+G S IPK+QK +++FF EL DEA A G + L K + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R++ + E + E +D + +E A+ ++ + ++ ++ KI+ + NE+I W K AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPTNTIFDAKRLIGRRFDDGVVQSDMKHWPFTVINDSTRPKVQVDYKGEAKSFYP--EEISSMVLVKMKEIAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKHKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDF--YTSITRARFEELNADLFRGTLDPVEKSL----RDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAADKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSSKNSLESYAFNMKSTV-EDEKLKGKISDEDKQKIM-DKCNEVISWLDKNQTAERDEFEHQQKELEKVCNPIITKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: ENSAMXT00000037064.1 (heat shock 70 kDa protein [Source:NCBI gene;Acc:111193176]) HSP 1 Score: 162.155 bits (409), Expect = 5.447e-42 Identity = 154/612 (25.16%), Postives = 288/612 (47.06%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEE-DINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSIGVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGK-DDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE---NSMPNDEHMNEKDRELE-IAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPI---DLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPIL 1890
IGI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF+ K ++ K T EEI + + +K AE++L KV + +TVP F++SQ + K +AGL +++ + +A +Y +++ ++ + +VL+ D+ + ++ +++ + EV T ++ G F L ++ + +++ + + K L R + + L++S +S+ V ITRA+++E+ S+ + + L++ ++ +S I +IVL+G S IPK+QK +++FF +L DEA A G + + G + ++L D+ + IE G + +I+R +P K+++ F+ D+Q ++I V EG++ + + N LG+ + P RG+ + +++NG + V+A D T Q ++ I R++ +E D++ E D + E IA K +E A+ ++ NS + +K I D K + E N+ I W A+ + E+ K E PI+
Sbjct: 9 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPNNTVFDA-KRLIGRKFDDPVVQSDMKHWPFQVVSDGGKPKVQVEYKGEQKT--FNPEEISSMVLVKMKEIAEAYLGQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKKGERHVLIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRALRRLRTACERAKRTLSSSSQASIEIDSLHEGVDFYTSITRARFEEMCSDLFRGTLEPVEKALRDAKMDKSQIHEIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDTSGNVQDLLLLDVAPLSLGIETAGGVMATLIKRNTTIPTKQTQTFSTYADNQPGVLIQVFEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKQNKITITNDKGRLSKEEIERMVQEADQYKAEDDLQREKIAAK--NSLESFAFNMK-----NSVEDENLKGKISEDDKKKVIEKCNQAISWLENNQLADKEEFEHQLKELEKVCNPII 609
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa5 (heat shock protein 5 [Source:NCBI gene;Acc:378848]) HSP 1 Score: 198.364 bits (503), Expect = 2.961e-55 Identity = 164/617 (26.58%), Postives = 305/617 (49.43%), Query Frame = 1
Query: 88 ETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTF-DEIVS--MKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
E T+IGI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GR++ D V +K +PF K +++ + ++ EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L+T + S G D +E + TRAK++EL + K + +++ +LK++DI +IVL+G S IPK+Q+ ++ F E DEA A G + G+ G+D+ + V+L D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + ++ NG + V+A D T + ++ I R+ +E M +D E + D+ ++ + R E+E AY ++ I ++ S D + ++++V + I W + A+ D + KK E ++PI+ +
Sbjct: 30 ENMGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRSWTDPTVQHDIKFWPFTVLEKKGKPHIQVEVIAGESKTFAP-EEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDHGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDHRAVQKLRREVEKAKRTLSTQHQARIDIESFYDGDDFSETL--TRAKFEELNMDLFRSTMKPVQKVMEDSDLKKTDIDEIVLVGGSTRIPKIQQLVKELFNGKEPSRGINPDEAVAYGAAVQAGVLSGEDNTGDLVLL-DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTAADNQPTVTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVSAEDKGTGNKNKITITNDQNRLTPEEIERMVSDAERFADDDKRVKERVEARNELESYAYSLKNQIGDKEKLGGKL-SDEDRETVEKAVEDKIAWLEGHQEADTDDFKAQKKELEEVVQPIVSKLY 640
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa9 (heat shock protein 9 [Source:ZFIN;Acc:ZDB-GENE-030828-12]) HSP 1 Score: 136.732 bits (343), Expect = 5.419e-34 Identity = 127/547 (23.22%), Postives = 258/547 (47.17%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYSS--SSVMVIDSLEYLAGRTFDEI-VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXREV-KYLQAHLTTSYLTEFRWNSIGVDVAEV----IPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKS--FERINVKENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEI 1710
+IGI G +++ + + ++++ N+ G T +V F + L+G AK + + + + L GR FD+ V +KI N M S +I ++ +K +AE+F+ + V + +TVP F++SQ + K ++GL +++ + +A +Y +++ ++ + + V D+ + ++ ++ + EV T+ + G F AL Y++ +++ + L L RE + + L++S T+ + +D + + +TR++++ ++ + I + L++ E+ +SDI ++L+G +PK+Q+ ++ F ++ N DEA AIG G D + V+L D+ + IE G + +I R +P KKS+ F+ D Q ++ I V +G++ +A N LGQ P RG+ + +++NG + V+A D T ++++VI+ S + + EN + N E E+DR + + + E I ++I
Sbjct: 54 AVIGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRFDDSDVQKDMNNLSYKIVRASNGDAWVEAHGKMYSP---SQIGAFVLLKMKETAENFMGTSVKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKADDKV-IAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDNALLKYIVKEFKRESGVDLTKDSMALQRVREAAEKAKCELSSSLQTDINLPYLTMDSSGPKHLNMKLTRSQFENIVGDLIRKTIAPCQKALQDGEVAKSDIGDVILVGGMTRMPKVQQTVQEVFGRAPSKAVN-PDEAVAIGAAIQGGVLAGD--VTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVFQGEREMAGDNKNLGQFTLVGVPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDEI-ENMVKNAEKYAEEDRRRKDRVEAVNQAEGIVHDI 592
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa14 (heat shock protein 14 [Source:NCBI gene;Acc:565232]) HSP 1 Score: 95.1301 bits (235), Expect = 6.208e-21 Identity = 115/506 (22.73%), Postives = 218/506 (43.08%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKV--LIGKEAKYSSSSVMVIDSLEYLAGRTFDEIVSMKQYPFRFXXXXXXXXXXXXXXTNDMT--SYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE--TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXREVKYLQAH-LTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG-IGKIGLQFGKDD--------QINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTF----LGQI---EFRRPPTGLRGL-TLFNIEIAVESNGYIFVTATD 1545
+G+H G +++ +++I N G+ T +V F + +K+ L K+ + +++ V+ L R D++V ++Y N+ T ++T E+ T I +K +A + + +T P +F+ Q+ ++ A AG +++ + +A+ ++ I + + VLV + + + V+G+ G +F+ AL +YL +QK L+ + + H L+T ++ +S+ G+D ITRA++D L S + + + L +I L SD ++VL G S IPKLQ+ ++ F EL DE A+G + G+ G+D I L DIL K+ E V+ G LP ++ F + ++++V EG VA+ ++F L Q+ + ++ GLR + T+F + + +G + +T TD
Sbjct: 4 VGVHLGSTCACVAIYKDGRADVIANDAGDRVTPAMVAFRDSEKIVGLAAKQGRIRNATTTVVGVKRILGHRFEDDVV--QKYISSSSCPVIEKDGCPVFSINNGTVKKHITRHEVATLILQKMKETALFAVGADAKDAVITTPLNFTTQQVDELRQAAESAGFNVLRILSEPAAALLAFGIGQESSHSKCKVLVYKLGGTCAYATAIEVNSGLYRVLGSVSDDTVGGEEFTEALAEYLATEFQKFHRQDLRGNSRAMMKLHTNAEMAKHVLSTMAISNCFVDSLHDGLDFE--CNITRARFDSLCSVLFQQSLQPIHDLLAQINLTTSDFQKVVLCGGSARIPKLQQLLQEQFVGSELMCSIPVDEVIALGAAAEAGILLGRDAVRFEPEALSIECASL-DILVKEQD-EAGQDCYTVVFPVGTPLPARRQHTFQAP-GTLPSVLVDVYEG---VAKGSSFEGVHLAQLVLKDLQQQDNGLRDISTVFTM----KRDGSLLITCTD 495
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa13 (heat shock protein 70 family, member 13 [Source:ZFIN;Acc:ZDB-GENE-070410-58]) HSP 1 Score: 47.3654 bits (111), Expect = 8.461e-6 Identity = 34/128 (26.56%), Postives = 64/128 (50.00%), Query Frame = 1
Query: 421 LTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNY-GSRKFSRALEDYL 801
+T E + + L+ AE L V L VP +F E Q S A +AGL +++ + +A +Y ++E E +VLV+D+ +T++ +++ Q G +N+ G + F++ L ++L
Sbjct: 145 VTPEWVGAQMLDQLRLLAEERLGLPVRYAVLAVPAEFDERQRNSTIKAATMAGLEVLRVVNEPTAAALAYGLHEEESVSSVLVVDLGGGTTDVSLLT-KQGGMFFTRAMAGNNHLGGQDFTQRLVEHL 271
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA3 (ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm; SSA3 has a paralog, SSA4, that arose from the whole genome duplication [Source:SGD;Acc:S000000171]) HSP 1 Score: 167.162 bits (422), Expect = 1.399e-44 Identity = 152/609 (24.96%), Postives = 291/609 (47.78%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYSSS---SVMVIDSLEYLAGRTFDE---IVSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINET-EEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIG--LQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPNDEHMNEKDRELEIA-YKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPIL 1890
+GI G Y ++ + E+I N G T V F + ++ LIG AK ++ V D+ + L GR FD+ K +PF+ ++ ++ K T T EEI + + + +K +AE++L + V +TVP F++SQ + K +AG+ +++ + +A +Y +++ + NVL+ D+ + ++ ++S D+ EV T ++ G F L ++L +++ T+ + N + L R + + L++S T +S+ G+D +TRA+++EL ++ + + LK+ +L +S I +IVL+G S IPK+QK + +FF E DEA A G L + + ++L D+ + IE G + +I R +P KKS+ F+ D+Q ++I V EG++ + N LG+ E P RG+ ++ +++NG + V+A + T ++ I R++ + + M ++ D E E + + ++E A+ ++ + + +SF ++V D K L+ + E I+W A + ++ +K E PI+
Sbjct: 5 VGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQAAINPHNTVFDA-KRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGE--TKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDF--YTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLK-NTINEASFKEKVGED-DAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIM 605
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA4 (Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the HSP70 family; cytoplasmic protein that concentrates in nuclei upon starvation; SSA4 has a paralog, SSA3, that arose from the whole genome duplication [Source:SGD;Acc:S000000905]) HSP 1 Score: 165.622 bits (418), Expect = 4.914e-44 Identity = 153/609 (25.12%), Postives = 286/609 (46.96%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYSSS---SVMVIDSLEYLAGRTFDE---IVSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIG--LQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPIL 1890
+GI G Y ++ + E+I N G T V F + ++ LIG AK ++ V D+ + L GR FD+ K YPF+ K ++ K T T EEI + I T +K +AE+FL ++V +TVP F++SQ + K +AGL +++ + +A +Y +++ ++++ NVL+ D+ + ++ ++S D+ EV T ++ G F L ++L +++ + L + L R + + L++S T +S+ G+D ITRA+++EL ++ + + L + +L +S I +IVL+G S IPK+QK + +FF E DEA A G L + ++L D+ + IE G + +I R +P KKS+ F+ D+Q ++I V EG++ + N LG+ E P RG+ + +++NG + V+A + T ++ I R++ + + + E +D + + + ++E A+ ++ + +N +F ++V D + L+ + + I W A + + +K E PI+
Sbjct: 5 VGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQAAMNPHNTVFDA-KRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGE--TKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDF--YTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSEN-NFKEKVGEE-DARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIM 605
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: KAR2 (ATPase involved in protein import into the ER; also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p [Source:SGD;Acc:S000003571]) HSP 1 Score: 160.999 bits (406), Expect = 2.504e-42 Identity = 149/606 (24.59%), Postives = 292/606 (48.18%), Query Frame = 1
Query: 85 CETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTE-TXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE--NSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEA 1872
E T+IGI G Y +++ +E++ N G T V F + D+ LIG AK +++ I ++ L G +++ +K PF K+ + +K T EEI I +K AE +L +KV +TVP F+++Q + K +AGL +++ + +A +Y +++++++ ++V D+ + ++ ++S + EV T ++ G F + L+ ++K N K + LKRE + + L++ T +S G+D++E + TRAK++EL + + K + L++ L++ D+ IVL+G S IPK+Q+ + ++F + DEA A G ++ + +VL D+ + IE G + +I+R +P KKS+ F+ D+Q ++I V EG++ +++ N LG+ E P RG+ + A+++NG + V+ATD T + + I R+ +E + E +D ++ + R ++E+ A+ ++ + N ++++ D + L ++ N+++EW IA E+ ++FE+
Sbjct: 46 VENYGTVIGIDLGTTYSCVAVMKNGKTEILANEQGNRITPSYVAFTD-DERLIGDAAKNQVAANPQNTIFDIKRLIGLKYNDRSVQKDIKHLPFNVVNKDGKPAVEVSVKGE--KKVFTPEEISGMILGKMKQIAEDYLGTKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIVNEPTAAAIAYGLDKSDKEHQIIVYDLGGGTFDVSLLSIENGVFEVQATSGDTHLGGEDFDYKIVRQLIKAFKKKHGIDVSDNNKALAKLKREAEKAKRALSSQMSTRIEIDSFVDGIDLSETL--TRAKFEELNLDLFKKTLKPVEKVLQDSGLEKKDVDDIVLVGGSTRIPKVQQLLESYFDGKKASKGINPDEAVAYGAAVQAGVLSGEEGVEDIVLLDVNALTLGIETTGGVMTPLIKRNTAIPTKKSQIFSTAVDNQPTVMIKVYEGERAMSKDNNLLGKFELTGIPPAPRGVPQIEVTFALDANGILKVSATDKGTGKSESITITNDKGRLTQEEIDRMVEEAEKFASEDASIKAKVESRNKLENYAHSLKNQV--NGDLGEKLEEE-DKETLLDAANDVLEWLDDNFETAIA--EDFDEKFES 641
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA2 (HSP70 family ATP-binding protein; involved in protein folding, vacuolar import of proteins; required for ubiquitin-dependent degradation of short-lived proteins; associated with chaperonin-containing T-complex; 98% identical to paralog Ssa1p with distinct functional specificity in propagation of yeast [URE3] prions and vacuolar-mediated degradation of gluconeogenesis enzymes; binds tRNA, has role in tRNA nuclear import during starvation [Source:SGD;Acc:S000003947]) HSP 1 Score: 155.606 bits (392), Expect = 1.113e-40 Identity = 148/616 (24.03%), Postives = 285/616 (46.27%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYSSS---SVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDD--QINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKEN-----SMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y ++ + ++I N G T VGF + ++ LIG AK ++ + V D+ + L GR F++ MK +PF+ + + ++ K T T E+I + + +K +AES+L +KV +TVP F++SQ + K +AGL +++ + +A +Y +++ ++ +VL+ D+ + ++ ++S + EV T ++ G F L ++ + +++ + L + L R + + L++S T +S+ G+D ITRA+++EL ++ + L++ +L +S + +IVL+G S IPK+QK + ++F E DEA A G D+ + ++L D+ + IE G + +I R +P KKS+ F+ D+Q ++I V EG++ + N LG+ E P RG+ + V+SNG + V+A + T ++ I R++ KE+ + ++ IA K ++E IAY ++ I + +++ D + + E I W + A + ++ K + PI+ +
Sbjct: 5 VGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTER-LIGDAAKNQAAMNPANTVFDA-KRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGE--TKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDF--YTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLS-KEDIEKMVAEAEKFKEEDEKESQRIASK--NQLESIAYSLKNTISEAGDKLEQA----DKDAVTKKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQ 607
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA1 (ATPase involved in protein folding and NLS-directed nuclear transport; member of HSP70 family; required for ubiquitin-dependent degradation of short-lived proteins; forms chaperone complex with Ydj1p; localized to nucleus, cytoplasm, cell wall; 98% identical to paralog Ssa2p with different functional specificity in propagation of yeast [URE3] prions, vacuolar-mediated degradations of gluconeogenesis enzymes; general targeting factor of Hsp104p to prion fibrils [Source:SGD;Acc:S000000004]) HSP 1 Score: 154.836 bits (390), Expect = 2.132e-40 Identity = 148/616 (24.03%), Postives = 284/616 (46.10%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYSSS---SVMVIDSLEYLAGRTFDEI---VSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDD--QINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKEN-----SMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y ++ + ++I N G T V F + ++ LIG AK ++ S V D+ + L GR F++ MK +PF+ + + ++ K T T E+I + + +K +AES+L +KV +TVP F++SQ + K +AGL +++ + +A +Y +++ ++ +VL+ D+ + ++ ++S + EV T ++ G F L ++ + +++ + L + L R + + L++S T +S+ G+D ITRA+++EL ++ + L++ +L +S + +IVL+G S IPK+QK + ++F E DEA A G D+ + ++L D+ + IE G + +I R +P KKS+ F+ D+Q ++I V EG++ + N LG+ E P RG+ + V+SNG + V+A + T ++ I R++ KE+ + ++ IA K ++E IAY ++ I + +++ D + + E I W + A + ++ K + PI+ +
Sbjct: 5 VGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTER-LIGDAAKNQAAMNPSNTVFDA-KRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGE--TKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDF--YTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLS-KEDIEKMVAEAEKFKEEDEKESQRIASK--NQLESIAYSLKNTISEAGDKLEQA----DKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQ 607
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO33296 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSL5]) HSP 1 Score: 202.986 bits (515), Expect = 1.295e-56 Identity = 166/608 (27.30%), Postives = 301/608 (49.51%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSR-ALEDYLLCLYQKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPIL 1890
T+IGI G Y + + E+I N G T V F E + LIG AK ++ V D+ + L GR++D+ +K +PF+ KNK +K D EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + +E ++ +K + K+ + + L+REV+ + L+T + S G D +E++ TRA+++EL ++ K + L++ +LK+S+I +IVL+G S IPK+Q+ +++FF E DEA A G G ++ VVL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG+ + P RG+ + ++ NG + V+A D T ++++ I R+ ++ M ND E ++D++ + + R E+E AY ++ + ++ S D K + E+V + I W K A + D + KK E ++PI+
Sbjct: 34 TVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTEEGERLIGDGAKNQLTTNPENTVFDA-KRLIGRSWDDTSVQNDLKFFPFKVVDKNKKPHVQVK--VKDEIKTFAAEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGAIAGLTVMRIINEPTAAAIAYGMDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQNVMEHFIKLYKKKKGKNIRKDNRAVQKLRREVEKAKRALSTQHQARVEIESFFEGEDFSEML--TRARFEELNAKLFKSTLKPVQKVLEDADLKKSEIHEIVLVGGSTRIPKVQQLVKDFFEGKEPSRGINPDEAVAYGAAVQAGVLGGEEDTGEVVLLDVNPLTLGIETVGGVMTKLISRNTVIPTKKSQVFSTAADNQNTVTIQVFEGERPMTKDNHPLGKFDLNGIPPAPRGVPQIEVTFEIDVNGILRVSAEDKGTGNKEKITITNDQNRLTPEDIERMVNDAEKFADEDKKTKEKVEARNELESYAYSLKNQVGDKEKLGGKL-SEDDKKTITEAVEKAISWMDKNQDASVEDFKKEKKELEDVVQPIV 635
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO44530 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV88]) HSP 1 Score: 167.162 bits (422), Expect = 3.648e-44 Identity = 149/590 (25.25%), Postives = 273/590 (46.27%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINET-EEDINVLVIDIAEDSTNLVVVSCDQNGQ-EVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYA 1830
IGI G Y + + E+I N G T VGF + ++ L+G AK + + D+ + L GR +D+ MK +PF+ N K ++ K T EEI + + +K +AE++L KV S +TVP F++SQ + K +AGL +++ + +A +Y ++++ + NVL+ D+ + ++ +++ D EV T ++ G F L ++ + +++ + + + R + + L++S +S+ G+D I+RA++++L S+ + L + + +SDI ++VL+G S +PK+QK + +F L DEA A G + L K D++ V+L D+ + IE G + +IER +P K ++ FT D+Q + I V EG++ + + N LG+ + P RG+ + +++NG + V+A D T + I R++ +E + M ND E +D R +E A+ ++ I + S ++ S D +K V E++ W K S A
Sbjct: 7 IGIDLGTTYSCVGVFQNGKVEIIANDQGNRTTPSYVGFTDTER-LVGDAAKNQVALNPENTIFDA-KRLIGRRYDDATVQSDMKLWPFKIISDNNKPKIQVEYKGERKT--FAAEEISSMVLGKMKETAEAYLGQKVTSAVITVPAYFNDSQRQATKDAGTIAGLNVLRVINEPTAAALAYGLDKSLSGEKNVLIFDLGGGTFDVSILTIDDGSLFEVKSTAGDTHLGGEDFDNRLVNHFVAEFKRKYKKDMSKNSRAMRRLRTACERAKRTLSSSTEASIEVDSLFEGIDF--YTKISRARFEDLCSDLFLSCLDPVNKALSDAKFSKSDIHEVVLVGGSTRVPKIQKMLEEYFSGKSLNKSINPDEAVAYGAAVQAAILSGDKSDEVKDVLLVDVAPLSLGIETAGEVMTKLIERNARIPTKATQTFTTYSDNQPAVTIRVFEGERPLTKHNNLLGKFDLSGIPPAPRGVPQIEVTFDIDANGILNVSAKDKSTGKTGSITITNDKGRLSKEEIDRMINDAEKYKSEDEAQREKIAARNRLESYAFGVKSAISEPS--LEGKLSQSDKDTVKNKVEEVLNWLEKNSLA 588
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO37280 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG65]) HSP 1 Score: 163.31 bits (412), Expect = 9.971e-43 Identity = 160/625 (25.60%), Postives = 293/625 (46.88%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLY-QKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKE--IELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVI--------RKSFERINVKENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPI---DLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + V D+ + L GR FD+ V M +PF + + K ++ K + S+ EEI + + T +K +AE++L +KV +TVP F++SQ + K +AGL +++ + +A +Y +++ + NVL+ D+ + ++ V++ + EV T ++ G F + D+ + + QK + NK+ + L+ + + L++S +S+ G+D ITRA+++EL + + + + +++ I + I IVL+G S IPK+QK ++ F EL DEA A G + L KDD + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + N LG+ E P RG+ + +++NG + V+A D T + ++ I ++ ER+ V E S +E ++DR + + +E AY ++ + + +VK I D K + + E+++W AE + E +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFSDTER-LIGDAAKNQVAMNPENTVFDA-KRLIGRKFDDPVVARDMTHWPFHVIREGERPKIQVEFK-GEKKSFFP-EEISSMVLTKMKETAEAYLGAKVTDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGVERNVLIYDLGGGTFDVSVLTIEDGIFEVKSTAGDTHLGGEDFDNKMVDHFVKQFKQKYKKDITPNKRAMRRLRTACERAKRTLSSSTQASIEIDSLFEGIDF--YTSITRARFEELNQDLFKKTTEPVEQAIRDSKIPGGKESIHDIVLVGGSTRIPKIQKMLQELFGGKELNKSINPDEAVAYGAAVQAAILHGDKDDTVKDLLLLDVAPLSMGIETAGGVMSVLIKRNSTIPTKQTQTFTTYSDNQPGVLIQVFEGERSMTAHNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERM-VNEASKYKEEDEKQRDR-----IQTKNSLESYAYSMKSTVEDD-----KVKDKISEEDKKAILDKCTEVLKWLDTNQTAEKDEFEYHQKELEKVCNPIITKLYQ 614
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO30323 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T144]) HSP 1 Score: 150.599 bits (379), Expect = 1.774e-38 Identity = 150/623 (24.08%), Postives = 286/623 (45.91%), Query Frame = 1
Query: 91 TSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLY-QKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDE----LISETIFELEKTLISFLKEIELK-RSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
T IGI G Y + + E+I N G T V F + ++ L+G AK + + I + L GR FD+ MK + F + K ++ K T + EEI + + +K +AE++L KV +TVP F++SQ + K ++GL +++ + +A +Y +++ ++ NVL+ D+ + ++ V+S + EV TH ++ G F + D+ + + QK + NK+ + L+ + + L++S +S+ G+D ITRA+++E L +T+ +EK + K+ +L+ + I +IV++G S IPK+Q ++NFF EL DEA A G + L K + ++L D+ + +E G + I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ ++ V+SNG + V+A D T + ++ I R++ + E + E D + + + +E A+ ++ +++ ++ K++ ++W AE +++ +K E PI+ +
Sbjct: 2 TKAPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDEER-LVGDAAKNQVAMNPTNTIFDAKRLIGRRFDDPGVKDDMKHWSFEVVNEAGRPKVKVEYKGETKTFFA--EEISSMVLNKMKETAEAYLGCKVTDAVVTVPAYFNDSQRQATKDAGVISGLNVLRIINEPTAAAIAYGLDKKVGQERNVLIFDLGGGTFDVSVLSIEDGIFEVKSTHGDTHLGGEDFDNNMVDFFVKQFKQKYKKDITPNKRALRRLRTACERAKRTLSSSTQASIEIDSLYDGIDF--YTSITRARFEEMNAHLFKKTLEPVEKAI----KDSKLESKEKIDEIVMVGGSTRIPKIQSLLQNFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEATQDLLLLDVAPLTLGLETAGGVMTAAIKRNTTIPTKQTQTFTTYSDNQTSVLIQVYEGERSLTKDNNLLGKFELSGIPPAPRGVPQIDVTFDVDSNGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVKEAEKFKAADEAVRERIQSKNSLESYAFSMK-STMEDEKVKDKLSEDEREKVISR-CKATLDWLEHNQSAEKEEIDAHQKELEGVCNPIITKLYQ 613
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO47723 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLN7]) HSP 1 Score: 137.502 bits (345), Expect = 4.306e-34 Identity = 118/506 (23.32%), Postives = 241/506 (47.63%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYSS--SSVMVIDSLEYLAGRTFD--EIVS-MKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXREV-KYLQAHLTTSYLTEFRWNSIGVDVAEV----IPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKS 1587
+ GI G +++ D ++ ++I N+ G T +V F + L+G A+ + + + + + GR FD EI +K ++ + + + + ++ ++ +K +AES+L + V + +TVP F++SQ + K +AGL +++ + +A +Y +++TE+ I + V D+ + ++ ++ + EV T+ + G F L +L+ ++K + L L RE + + L++S T+ I VD + + ++R+K++ L+++ I L++ E+ + +I ++L+G +PK+Q+ +++ F ++ N DEA AIG G D + V+L D+ + IE G + +I R +P KKS+ F+ D Q ++ I V +G++ +A N LGQ + P RG+ + +++NG + V+A D T ++++VI+ S
Sbjct: 13 AVCGIDLGTTNSCVAVMDGKTPKVIENAEGSRTTPSVVAFTPEGERLVGAPARRQAITNPQNTLYATKRYIGRRFDAPEIKKDLKNVSYKIVRASNGDAWFEVAG-----KVYSPSQVGAFVLMKMKETAESYLGTNVNNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTEDKI-IAVYDLGGGTFDISILEIQKGVFEVKATNGDTYLGGEDFDNTLLKFLIAEFKKESGVDLSKDSMALQRLREAAEKAKIELSSSVQTDINLPYITVDASGPKHLNMKLSRSKFESLVADLINRTVGPCKKCLQDAEINKGEIGDVLLVGGMTRMPKVQQTVQDIFGRVPSKAVN-PDEAVAIGAAIQGGVLAGD--VKDVLLLDVTPLSLGIETLGGVFTKLITRNTTIPTKKSQVFSTAADGQTQVEIKVFQGEREMAIDNKLLGQFQLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDKGTGREQQIVIQSS 509
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hspa5 (heat shock protein family A (Hsp70) member 5 [Source:NCBI gene;Acc:101157378]) HSP 1 Score: 207.994 bits (528), Expect = 4.496e-58 Identity = 170/609 (27.91%), Postives = 301/609 (49.43%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPIL 1890
T+IGI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GR++ + +K +PF+ K I I M ++ EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ + + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L+ + S G D +E + TRAK++EL + K + L++ +LK+S+I +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G++D VVL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ ++ M ND E ++D+ L+ R E+E AY ++ I ++ S D + ++++V E IEW + AE D + KK E ++PI+
Sbjct: 27 TVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRSWGDSSVQQDIKYFPFKVIEKKSKPHIQIDIGGGQMKTFAP-EEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSAQHQARIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSEIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEED-TGDVVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMVNDAERFADEDKRLKERIDARNELESYAYSLKNQIGDKEKLGGKL-SDDDKETIEKAVEEKIEWMESHQDAETEDFQAKKKELEEVVQPII 629
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hspa5 (heat shock protein family A (Hsp70) member 5 [Source:NCBI gene;Acc:101157378]) HSP 1 Score: 207.994 bits (528), Expect = 4.496e-58 Identity = 170/609 (27.91%), Postives = 301/609 (49.43%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK---YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMT-ETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIG-KIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPIL 1890
T+IGI G Y + + E+I N G T V F + LIG AK S+ V D+ + L GR++ + +K +PF+ K I I M ++ EEI + T +K +AE++L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ + + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + ++ + LY+K T + K+ + + L+REV+ + L+ + S G D +E + TRAK++EL + K + L++ +LK+S+I +IVL+G S IPK+Q+ ++ FF E DEA A G + G+ G++D VVL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N LG + P RG+ + ++ NG + VTA D T + ++ I R+ ++ M ND E ++D+ L+ R E+E AY ++ I ++ S D + ++++V E IEW + AE D + KK E ++PI+
Sbjct: 27 TVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTVFDA-KRLIGRSWGDSSVQQDIKYFPFKVIEKKSKPHIQIDIGGGQMKTFAP-EEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSAQHQARIEIESFFEGEDFSETL--TRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSEIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEED-TGDVVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMVNDAERFADEDKRLKERIDARNELESYAYSLKNQIGDKEKLGGKL-SDDDKETIEKAVEEKIEWMESHQDAETEDFQAKKKELEEVVQPII 629
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hsp70-3 (heat shock protein 70 [Source:NCBI gene;Acc:100125493]) HSP 1 Score: 170.244 bits (430), Expect = 1.116e-44 Identity = 155/618 (25.08%), Postives = 293/618 (47.41%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF+ + K ++ K T Y EEI + + T +K +E++L V + +TVP F++SQ + K +AGL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + ++ N K + R + + L++S +S+ G D ITRA+++EL ++ TI +EK L ++ ++ +S I +VL+G S IPK+QK +++ F +L DEA A G + L K + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R++ + E + E +D + +E +A+ ++ + + +Q S D K + + NEII W K AE + E+ +K E PI+ +
Sbjct: 7 VGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPANTVFDA-KRLIGRKFDDAVVQSDMKHWPFKVVNDSSKPKVEVEYKGEIKTFYP--EEISSMVLTKMKEISEAYLGKSVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFITEFKRKFKKEITNNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGTDF--YTSITRARFEELNADLFRGTIEPVEKAL----RDAKMDKSQIHDVVLVGGSTRIPKIQKLLQDLFNGRDLNKSINPDEAVAYGAAVQAAILAGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNILGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEQFKAEDESQRDKITAKNSLESLAFNMKSTV--DDEKLQDKISSEDKKTIVDKCNEIIAWLDKNQMAEKDEYEHQQKELEKVCNPIISKLYQ 612
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hsp70-3 (heat shock protein 70 [Source:NCBI gene;Acc:100125493]) HSP 1 Score: 170.244 bits (430), Expect = 1.118e-44 Identity = 155/618 (25.08%), Postives = 293/618 (47.41%), Query Frame = 1
Query: 106 IGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+GI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF+ + K ++ K T Y EEI + + T +K +E++L V + +TVP F++SQ + K +AGL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + ++ N K + R + + L++S +S+ G D ITRA+++EL ++ TI +EK L ++ ++ +S I +VL+G S IPK+QK +++ F +L DEA A G + L K + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R++ + E + E +D + +E +A+ ++ + + +Q S D K + + NEII W K AE + E+ +K E PI+ +
Sbjct: 24 LGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPANTVFDA-KRLIGRKFDDAVVQSDMKHWPFKVVNDSSKPKVEVEYKGEIKTFYP--EEISSMVLTKMKEISEAYLGKSVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFITEFKRKFKKEITNNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGTDF--YTSITRARFEELNADLFRGTIEPVEKAL----RDAKMDKSQIHDVVLVGGSTRIPKIQKLLQDLFNGRDLNKSINPDEAVAYGAAVQAAILAGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNILGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEQFKAEDESQRDKITAKNSLESLAFNMKSTV--DDEKLQDKISSEDKKTIVDKCNEIIAWLDKNQMAEKDEYEHQQKELEKVCNPIISKLYQ 629
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hsc70 (heat shock protein 70 cognate [Source:NCBI gene;Acc:100049425]) HSP 1 Score: 166.392 bits (420), Expect = 3.762e-43 Identity = 157/646 (24.30%), Postives = 298/646 (46.13%), Query Frame = 1
Query: 16 MAVYLNLLKFSFVTIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYS---SSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINE-TEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXR-EVKYLQAHLTTSYLTEFRWNSIGVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIG--IGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
+A L L+F G + +GI G Y + + E+I N G T V F + ++ LIG AK + + V D+ + L GR FD+ V MK +PF N K ++ K + Y EEI + + T +K AE++L V + +TVP F++SQ + K ++GL +++ + +A +Y +++ + NVL+ D+ + ++ +++ + EV T ++ G F + ++ + +++ + + + K + R + + L++S +S+ V ITRA+++EL ++ T+ +EK+L ++ ++ + I IVL+G S IPK+QK +++FF EL DEA A G + L K + + ++L D+ + IE G + V+I+R +P K+++ FT D+Q ++I V EG++ + + N LG+ E P RG+ + +++NG + V+A D T + ++ I R++ + E + E +D + +E A+ ++ + ++ ++ KIL + NE+I W K AE + E+ +K E PI+ +
Sbjct: 27 VAFALRCLRFPNTHFRPPTICFGSMSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER-LIGDAAKNQVAMNPTNTVFDA-KRLIGRRFDDHVVQSDMKHWPFNVINDNTRPKVQVEYKGETKSFYP--EEISSMVLTKMKEIAEAYLGKTVNNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKYKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLDPVEKSL----RDAKMDKGQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSAKNGLESYAFNMKSTV-EDEKLAGKISDEDKQKIL-DKCNEVISWLDKNQTAERDEYEHQQKELEKVCNPIITKLYQ 662
BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000060655.1 (SMESG000060655.1) HSP 1 Score: 1207.97 bits (3124), Expect = 0.000e+0 Identity = 629/631 (99.68%), Postives = 630/631 (99.84%), Query Frame = 1
Query: 16 MAVYLNLLKFSFVTIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYSSSSVMVIDSLEYLAGRTFDEIVSMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLYQKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSIGVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFHF 1908
MAVYLNLLKFSFVTIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYSSSSVMVIDSLEYLAGRTFDEIVSMKQYPFRFKIKNKYNKPYIKIKTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLL LYQKMTETKLKNKKNILHLKREVKYLQAHLTTSYLTEFRWNSIGVDVAEV+PITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFHF
Sbjct: 1 MAVYLNLLKFSFVTIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAKYSSSSVMVIDSLEYLAGRTFDEIVSMKQYPFRFKIKNKYNKPYIKIKTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLSLYQKMTETKLKNKKNILHLKREVKYLQAHLTTSYLTEFRWNSIGVDVAEVVPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFHF 631
BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000068215.1 (SMESG000068215.1) HSP 1 Score: 197.208 bits (500), Expect = 2.672e-54 Identity = 164/588 (27.89%), Postives = 294/588 (50.00%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLY-QKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKEN--SMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYA 1830
T+IGI G Y + + E+I N G T V F + + LIG AK +S+ I ++ GR FD+ +K YPF + NK NKP++++K + EEI + +K AES+L +V +TVP F+++Q + K ++GL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + DY + LY +K + K+ + + L+REV+ + L+ S+ S G D +E + TRA+++EL + K + L++ +LK+ D+++IVL+G S IPK+Q+ ++ F E DEA A G G ++ +VL D+ + IE G++ +I R ++P KKS+ F+ D+Q + I V EG++ + + N FLG+ + P RG+ + ++ NG + V+A D T + ++VI K R++ EN M ND E E D++L+ + + E+E AY ++ + + ++ S + KI+ ++ E I W K A
Sbjct: 36 TVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPF--LVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDYFIKLYRKKHGKDVRKDNRAVQKLRREVEKAKRSLSNSHSARIDIESFYDGDDFSETL--TRARFEELNMDLFKNTMKPVEKVLQDSDLKKEDVSEIVLVGGSTRIPKIQQLVKELFDGKEPSRGINPDEAVAFGAAVQAGVIGGAEETGDLVLLDVCPLTLGIETVGAVMTKLIPRNTVIPTKKSQIFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIVINKDQNRLS-PENIEKMINDAEKFAESDKKLKDKVEAKNELEGYAYSLKTQVNDKTKLGGKL-SADEQKIILDAAQETISWLEKNPQA 617
BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000068215.1 (SMESG000068215.1) HSP 1 Score: 197.208 bits (500), Expect = 2.766e-54 Identity = 164/588 (27.89%), Postives = 294/588 (50.00%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYLLCLY-QKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKEN--SMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYA 1830
T+IGI G Y + + E+I N G T V F + + LIG AK +S+ I ++ GR FD+ +K YPF + NK NKP++++K + EEI + +K AES+L +V +TVP F+++Q + K ++GL +++ + +A +Y +++ E + N+LV D+ + ++ +++ D EV+ T+ ++ G F + + DY + LY +K + K+ + + L+REV+ + L+ S+ S G D +E + TRA+++EL + K + L++ +LK+ D+++IVL+G S IPK+Q+ ++ F E DEA A G G ++ +VL D+ + IE G++ +I R ++P KKS+ F+ D+Q + I V EG++ + + N FLG+ + P RG+ + ++ NG + V+A D T + ++VI K R++ EN M ND E E D++L+ + + E+E AY ++ + + ++ S + KI+ ++ E I W K A
Sbjct: 37 TVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPF--LVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDYFIKLYRKKHGKDVRKDNRAVQKLRREVEKAKRSLSNSHSARIDIESFYDGDDFSETL--TRARFEELNMDLFKNTMKPVEKVLQDSDLKKEDVSEIVLVGGSTRIPKIQQLVKELFDGKEPSRGINPDEAVAFGAAVQAGVIGGAEETGDLVLLDVCPLTLGIETVGAVMTKLIPRNTVIPTKKSQIFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIVINKDQNRLS-PENIEKMINDAEKFAESDKKLKDKVEAKNELEGYAYSLKTQVNDKTKLGGKL-SADEQKIILDAAQETISWLEKNPQA 618
BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000062699.1 (SMESG000062699.1) HSP 1 Score: 194.126 bits (492), Expect = 3.482e-53 Identity = 157/612 (25.65%), Postives = 302/612 (49.35%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEIV---SMKQYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINETEEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKF-SRALEDYLLCLYQKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISETIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVK--ENSMPNDEHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAFH 1905
T+IGI G Y + + E+I N G T V F + LIG AK +++ + ++ + GR F++ MK +PF+ KN +++ N++ S+ EEI + +K AE++L KV +TVP F+++Q + +AGL +++ + +A +Y +++ + N+LV D+ + ++ +++ D EVI T+ ++ G F R + ++ +K + +K+ + L+REV+ + L+ ++ S+ G D +E + TRA+++EL + K + L++ E+K+ DI +IVL+G S IPK+Q+ ++ FF E DEA A G G ++ +VL D+ + IE G + +I R ++P KKS+ F+ D+Q + I V EG++ + + N FLG+ + P RG+ + ++ NG + V+A D T + +++I+K R+N + E + + E ++D++++ + + ++E AY ++ + ++ SP D + + ++V+E I W K AE + + KK+ E + PI+ +
Sbjct: 34 TVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVG-NEVKSFAP-EEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIKLYKKKKGKDITDDKRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETL--TRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEAVAFGAAVQAGVIGGVEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKL-SPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 640
BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000061528.1 (SMESG000061528.1) HSP 1 Score: 174.866 bits (442), Expect = 2.568e-46 Identity = 164/619 (26.49%), Postives = 294/619 (47.50%), Query Frame = 1
Query: 100 TIIGIHFGRKYVRMSLCDRESSELIPNSIGELKTQILVGFDEHDKVLIGKEAK--YSSSSVMVIDSLEYLAGRTFDEIVSMK---QYPFRFXXXXXXXXXXXXXXTNDMTSYLTIEEILTYIFTYLKTSAESFLNSKVFSIALTVPDDFSESQLLSIKAGANLAGLRIVKSSRDAISAIYSYEINET----EEDINVLVIDIAEDSTNLVVVSCDQNGQEVIGTHVISNYGSRKFSRALEDYL-LCLYQKMTETXXXXXXXXXXXXREVKYLQAHLTTSYLTEFRWNSI--GVDVAEVIPITRAKYDELISE----TIFELEKTLISFLKEIELKRSDIAQIVLLGSSFSIPKLQKEIRNFFYNHELRSENGFDEAPAIGIGKIGLQFGKDDQINYVVLPDILYKDISIEVYGSMSEVIIERGLILPNKKSKNFTLNFDSQIEIIINVLEGDKLVARRNTFLGQIEFRRPPTGLRGLTLFNIEIAVESNGYIFVTATDLETKIQKRLVIRKSFERINVKE-NSMPND-EHMNEKDRELEIAYKIREEIEDIAYEIRGHILQNSSFIQRVKSPIDLKILKESVNEIIEWFAKYSYAEIADLENVKKRFEANIKPILQNAF 1902
T+IGI G Y + + E+IPN G T + F + + LIG AK +++ V I ++ L GR + + K YPF+ + + IK + + EEI + +KT AE +L KV +TVP F+++Q + K +AGL +++ + +A +Y +++ ++ +LV D+ + ++ +++ DQ EV+ T+ ++ G F + + DY L +K + K+ + I L+REV+ + L++ T S+ G D +E + TRAK++EL ++ T+ +EK L++ LK++DIA+IVL+G S IPK+Q+ +R FF E DEA A G D ++L D+ + +E+ G + +I R +P K FT D+Q + V EG++ + + N FLGQ + P RG+ + +++NG + V+A D T ++ +VI R+ ++ + M D E E+D ++ + R E+E Y ++ + + ++ S DLK ++V ++I+W A D K E+ + PI+ +
Sbjct: 36 TVIGIDLGTTYSCVGIFKEGRVEIIPNDQGNRITPSYIAFTQDGERLIGDSAKNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFKVINVDNKPHISVNIKGEEKS--FQPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDAQRQATKNAGIIAGLIVLRIINEPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLLTIDQGVFEVVATNGDTHLGGEDFDQRVIDYFSLLYKKKKNKDLKKDIRAIQKLRREVEKAKRALSSVLTTRIEIESLIDGEDFSETL--TRAKFEELNADLFKSTLIPVEK----VLQDANLKKNDIAEIVLVGGSTRIPKVQELVRGFFNGKEPNKGINPDEAVAYGAAVQAGVLSGDSTTGDLLLLDVCPLTLGMELEGGVMAKLINRNTPIPTIKKDVFTTVVDNQNTVTTAVYEGERQLVKDNHFLGQFDLTGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMIKDAEKFKEEDESIKQRIEARSELEQYVYSMKNQLNDKTKLGGKISSD-DLKKSNDAVLKVIDWLDLNKSATKEDYIKQKSDIESILNPIVSKLY 645 The following BLAST results are available for this feature:
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30004217 ID=SMED30004217|Name=Endoplasmic reticulum chaperone BiP|organism=Schmidtea mediterranea sexual|type=transcript|length=1956bpback to top protein sequence of SMED30004217-orf-1 >SMED30004217-orf-1 ID=SMED30004217-orf-1|Name=SMED30004217-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=632bp MAVYLNLLKFSFVTIFAIVSNVGCETSETIIGIHFGRKYVRMSLCDRESSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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