DNA polymerase

Overview


Name	DNA polymerase
Smed ID	SMED30004136
Length (bp)	4341

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of DNA polymerase (SMED30004136) t-SNE clustered cells

Violin plots show distribution of expression levels for DNA polymerase (SMED30004136) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DNA polymerase (SMED30004136) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DNA polymerase (SMED30004136) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30004136

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 57

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30004136	h1SMcG0008134	Contig7504	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30004136	h1SMcG0008134	Contig7504	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
X1 cell	SMED30004136	h1SMcG0008134	SmedASXL_018375	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
Smed sexual biotype	SMED30004136	h1SMcG0008134	Contig19631	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30004136	h1SMcG0008134	Contig19631	newmark_ests	PMID:29674431 Fincher et al., 2018
nervous system	SMED30004136	h1SMcG0008134	dd_Smed_v4_9168_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30004136	h1SMcG0008134	dd_Smed_v4_9168_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30004136	h1SMcG0008134	dd_Smed_v4_9168_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30004136	h1SMcG0008134	dd_Smed_v4_9168_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30004136	h1SMcG0008134	dd_Smed_v4_9168_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30004136	h1SMcG0008134	Contig17348	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30004136	h1SMcG0008134	Contig17348	newmark_ests	PMID:29674431 Fincher et al., 2018
oocyte	SMED30004136	h1SMcG0008134	Contig55194	newmark_ests	PMID:28434803 Rouhana et al., 2017
oocyte	SMED30004136	h1SMcG0008134	Contig55194	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30004136	h1SMcG0008134	Contig55194	newmark_ests	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30004136	h1SMcG0008134	Contig55194	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
zeta neoblast	SMED30004136	h1SMcG0008134	dd_Smed_v4_9168_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
neoblast	SMED30004136	h1SMcG0008134	SMED_05156_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0008134	SMED_05156_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007547	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007547	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007546	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007546	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007548	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007548	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007544	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007544	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0008134	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0008134	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007549	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007549	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007545	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007545	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007537	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0007537	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022749	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022749	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022747	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022747	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022744	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022744	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022742	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022742	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022926	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022926	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022698	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022698	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022746	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022746	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022929	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022929	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022743	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022743	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022699	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022699	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022930	SMED_04360_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30004136	h1SMcG0022930	SMED_04360_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of DNA polymerase vs. Ensembl Human
Match: POLA1 (DNA polymerase alpha 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9173])

HSP 1 Score: 803.127 bits (2073), Expect = 0.000e+0
Identity = 559/1515 (36.90%), Postives = 822/1515 (54.26%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEGDSE--YMESGKEIFDESDEEDIKIGPKRKKSMK--NANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNRE--EIKAP--FLSKKKEEF-----KFDIHQPKVISSSKIKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVVSAGFATDTKLEEHKPLWETEEIEDESSNDK---------------YDPFE-----------NIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQA-------------QMTEVYSEV-KSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQL-----EIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP------GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY--HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELE----KPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMT---TGQFACPRCESGIMKPLLSSSLLNRQLGYYRF----------LLTGKENLSYKQK----ELLQMCSKY---VERVLERSDYMNVDFKSLMA 4282
            R RR++ SKK  + + L +LKKAK  G   K E+E    +Y+ V+EE Y KL + RQ D++I  D    Y+E G+EIFD+  E+D     ++ K  K  N + +N KK  +       ++ KS+F        + K ++ +    L   L   N E  +I  P   + KKK         F +H    + S KI     ++ P  T   P+   + +   +    E     ST E  E+         +  +D DFDEP E   V     A     +E +P    EE++ E+ + K               +D  +            +D S L L+           YW DAY D+   PGVVFLFGK   ES +  V+ C+ V  +ER +Y LP++                M +VY E  + I  K+ I   ++KPV K YAF+  DVP++++YL V+Y ++ P+LP DL G+TFS +FG NTS LE+F+++ ++KGPCWL     +  +   S CK+         + + K+ SPP   +++ ++KT+ N K++ NEI+A+   +H+   LD+A P   FQ++F +++ PKD + PY   + +  +   N K  V + A ER+L+   L K+H +DPDIIVGH + G++L +LLQR        W K GRLKRS  +PK+ G S   + ER AT GR++CDVE+SA+ELI+C+SY   +L+Q++L    K     +P+ ++  +++ S+ +  L++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNE+LLLHAF E  YIVPDK        +L     EID    +  K  ++K  YAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT+ R          +A  +  D   + + + P      GILP EIRKLVE R  VKQL+   +L+ + +LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT+ GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L  V    S G  + KQELKGLDIVRRDWC L+ + G  ++  IL ++ S + +  +I   L  I +++ N  + + +F I KALT++P++Y + +  PHV VAL INS GG  ++ +A DTV Y+IC DG++ TA+QRAY+P+++      ++  L+ID  YYLA Q+HPVV R+ EPID IDA  +A  LGLDP+++  HH ++  E D          +  ++ DC+     C  C  +   D   +      +P L    N++   S     V ++ KL   I R I  YY     C+           C    R L +    TG   CP C    ++P  S   L  QL +YR+          L T  E    K++    ++LQ   K     E+ L RS Y  V+   L A
Sbjct:   20 RARREKKSKK-GRQEALERLKKAKA-GEKYKYEVEDFTGVYEEVDEEQYSKLVQARQDDDWIVDDDGIGYVEDGREIFDDDLEDDALDADEKGKDGKARNKDKRNVKKLAV----TKPNNIKSMFIACAGKKTADKAVDLSKDGLLGDILQDLNTETPQITPPPVMILKKKRSIGASPNPFSVHTATAVPSGKIASPVSRKEPPLT---PVPLKRAEFAGDDVQVE-----STEEEQES-------GAMEFEDGDFDEPMEVEEVDLEPMAAKAWDKESEP---AEEVKQEADSGKGTVSYLGSFLPDVSCWDIDQEGDSSFSVQEVQVDSSHLPLVKGADEEQVFHFYWLDAYEDQYNQPGVVFLFGKVWIESAETHVSCCVMVKNIERTLYFLPREMKIDLNTGKETGTPISMKDVYEEFDEKIATKYKIMKFKSKPVEKNYAFEIPDVPEKSEYLEVKYSAEMPQLPQDLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKSPQLLNQPVSWCKVEAMALKPDLVNVIKDVSPPPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAAPKPPFQSHFCVVSKPKDCIFPYAFKEVIEKK---NVK--VEVAATERTLLGFFLAKVHKIDPDIIVGHNIYGFELEVLLQRINVCKAPHWSKIGRLKRS-NMPKLGGRSG--FGERNATCGRMICDVEISAKELIRCKSYHLSELVQQIL----KTERVVIPMENIQNMYSESSQLLYLLEHTWKDAKFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKK-GRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRV-------ASEAQKVTEDGEQEQIPELPDPSLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKEMVQ--------KMN----LEVIYGDTDSIMINTNSTNL---EEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAAL--VVEPTSDGNYVTKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQ-SRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKKSLPHVHVALWINSQGG--RKVKAGDTVSYVICQDGSNLTASQRAYAPEQL-----QKQDNLTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDPTQFRVHHYHKDEENDALLGGPAQLTDEEKYRDCERFKCPCPTCGTENIYDNVFDGSGTDMEPSLYRCSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICE--------EPTCRNRTRHLPLQFSRTGPL-CPACMKATLQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTPKVLQDYRKLKNTAEQFLSRSGYSEVNLSKLFA 1456

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Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEGDSE--YMESGKEIFDESDEEDIKIGPKRKKSMK--NANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNRE--EIKAP--FLSKKKEEF-----KFDIHQPKVISSSKIKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVVSAGFATDTKLEEHKPLWETEEIEDESSNDK---------------YDPFE-----------NIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQA-------------QMTEVYSEV-KSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQL-----EIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP------GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY--HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELE----KPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMT---TGQFACPRCESGIMKPLLSSSLLNRQLGYYRF----------LLTGKENLSYKQK----ELLQMCSKY---VERVLERSDYMNVDFKSLMA 4282
            R RR++ SKK  + + L +LKKAK  G   K E+E    +Y+ V+EE Y KL + RQ D++I  D    Y+E G+EIFD+  E+D     ++ K  K  N + +N KK  +       ++ KS+F        + K ++ +    L   L   N E  +I  P   + KKK         F +H    + S KI     ++ P  T   P+   + +   +    E     ST E  E+         +  +D DFDEP E   V     A     +E +P    EE++ E+ + K               +D  +            +D S L L+           YW DAY D+   PGVVFLFGK   ES +  V+ C+ V  +ER +Y LP++                M +VY E  + I  K+ I   ++KPV K YAF+  DVP++++YL V+Y ++ P+LP DL G+TFS +FG NTS LE+F+++ ++KGPCWL     +  +   S CK+         + + K+ SPP   +++ ++KT+ N K++ NEI+A+   +H+   LD+A P   FQ++F +++ PKD + PY   + +  +   N K  V + A ER+L+   L K+H +DPDIIVGH + G++L +LLQR        W K GRLKRS  +PK+ G S   + ER AT GR++CDVE+SA+ELI+C+SY   +L+Q++L    K     +P+ ++  +++ S+ +  L++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNE+LLLHAF E  YIVPDK        +L     EID    +  K  ++K  YAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT+ R          +A  +  D   + + + P      GILP EIRKLVE R  VKQL+   +L+ + +LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT+ GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L  V    S G  + KQELKGLDIVRRDWC L+ + G  ++  IL ++ S + +  +I   L  I +++ N  + + +F I KALT++P++Y + +  PHV VAL INS GG  ++ +A DTV Y+IC DG++ TA+QRAY+P+++      ++  L+ID  YYLA Q+HPVV R+ EPID IDA  +A  LGLDP+++  HH ++  E D          +  ++ DC+     C  C  +   D   +      +P L    N++   S     V ++ KL   I R I  YY     C+           C    R L +    TG   CP C    ++P  S   L  QL +YR+          L T  E    K++    ++LQ   K     E+ L RS Y  V+   L A
Sbjct:   26 RARREKKSKK-GRQEALERLKKAKA-GEKYKYEVEDFTGVYEEVDEEQYSKLVQARQDDDWIVDDDGIGYVEDGREIFDDDLEDDALDADEKGKDGKARNKDKRNVKKLAV----TKPNNIKSMFIACAGKKTADKAVDLSKDGLLGDILQDLNTETPQITPPPVMILKKKRSIGASPNPFSVHTATAVPSGKIASPVSRKEPPLT---PVPLKRAEFAGDDVQVE-----STEEEQES-------GAMEFEDGDFDEPMEVEEVDLEPMAAKAWDKESEP---AEEVKQEADSGKGTVSYLGSFLPDVSCWDIDQEGDSSFSVQEVQVDSSHLPLVKGADEEQVFHFYWLDAYEDQYNQPGVVFLFGKVWIESAETHVSCCVMVKNIERTLYFLPREMKIDLNTGKETGTPISMKDVYEEFDEKIATKYKIMKFKSKPVEKNYAFEIPDVPEKSEYLEVKYSAEMPQLPQDLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKSPQLLNQPVSWCKVEAMALKPDLVNVIKDVSPPPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAAPKPPFQSHFCVVSKPKDCIFPYAFKEVIEKK---NVK--VEVAATERTLLGFFLAKVHKIDPDIIVGHNIYGFELEVLLQRINVCKAPHWSKIGRLKRS-NMPKLGGRSG--FGERNATCGRMICDVEISAKELIRCKSYHLSELVQQIL----KTERVVIPMENIQNMYSESSQLLYLLEHTWKDAKFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKK-GRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRV-------ASEAQKVTEDGEQEQIPELPDPSLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKEMVQ--------KMN----LEVIYGDTDSIMINTNSTNL---EEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAAL--VVEPTSDGNYVTKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQ-SRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKKSLPHVHVALWINSQGG--RKVKAGDTVSYVICQDGSNLTASQRAYAPEQL-----QKQDNLTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDPTQFRVHHYHKDEENDALLGGPAQLTDEEKYRDCERFKCPCPTCGTENIYDNVFDGSGTDMEPSLYRCSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICE--------EPTCRNRTRHLPLQFSRTGPL-CPACMKATLQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTPKVLQDYRKLKNTAEQFLSRSGYSEVNLSKLFA 1462

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BLAST of DNA polymerase vs. Ensembl Human
Match: POLA1 (DNA polymerase alpha 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9173])

HSP 1 Score: 799.275 bits (2063), Expect = 0.000e+0
Identity = 559/1515 (36.90%), Postives = 821/1515 (54.19%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEGDSE--YMESGKEIFDESDEEDIKIGPKRKKSMK--NANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNRE--EIKAP--FLSKKKEEF-----KFDIHQPKVISSSKIKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVVSAGFATDTKLEEHKPLWETEEIEDESSNDK---------------YDPFE-----------NIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQA-------------QMTEVYSEV-KSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQL-----EIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP------GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY--HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELE----KPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMT---TGQFACPRCESGIMKPLLSSSLLNRQLGYYRF----------LLTGKENLSYKQK----ELLQMCSKY---VERVLERSDYMNVDFKSLMA 4282
            R RR++ SKK  + + L +LKKAK  G   K E+E    +Y+ V+EE Y KL + RQ D++I  D    Y+E G+EIFD+  E+D     ++ K  K  N + +N KK  +       ++ KS+F        + K ++ +    L   L   N E  +I  P   + KKK         F +H    + S KI     ++ P  T   P+   + +   +    E     ST E  E+         +  +D DFDEP E   V     A     +E +P    EE++ E+ + K               +D  +            +D S L L+           YW DAY D+   PGVVFLFGK   ES +  V+ C+ V  +ER +Y LP++                M +VY E  + I  K+ I   ++KPV K YAF+  DVP++++YL V+Y ++ P+LP DL G+TFS +FG NTS LE+F+++ ++KGPCWL        +   S CK+         + + K+ SPP   +++ ++KT+ N K++ NEI+A+   +H+   LD+A P   FQ++F +++ PKD + PY   + +  +   N K  V + A ER+L+   L K+H +DPDIIVGH + G++L +LLQR        W K GRLKRS  +PK+ G S   + ER AT GR++CDVE+SA+ELI+C+SY   +L+Q++L    K     +P+ ++  +++ S+ +  L++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNE+LLLHAF E  YIVPDK        +L     EID    +  K  ++K  YAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT+ R          +A  +  D   + + + P      GILP EIRKLVE R  VKQL+   +L+ + +LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT+ GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L  V    S G  + KQELKGLDIVRRDWC L+ + G  ++  IL ++ S + +  +I   L  I +++ N  + + +F I KALT++P++Y + +  PHV VAL INS GG  ++ +A DTV Y+IC DG++ TA+QRAY+P+++      ++  L+ID  YYLA Q+HPVV R+ EPID IDA  +A  LGLDP+++  HH ++  E D          +  ++ DC+     C  C  +   D   +      +P L    N++   S     V ++ KL   I R I  YY     C+           C    R L +    TG   CP C    ++P  S   L  QL +YR+          L T  E    K++    ++LQ   K     E+ L RS Y  V+   L A
Sbjct:   20 RARREKKSKK-GRQEALERLKKAKA-GEKYKYEVEDFTGVYEEVDEEQYSKLVQARQDDDWIVDDDGIGYVEDGREIFDDDLEDDALDADEKGKDGKARNKDKRNVKKLAV----TKPNNIKSMFIACAGKKTADKAVDLSKDGLLGDILQDLNTETPQITPPPVMILKKKRSIGASPNPFSVHTATAVPSGKIASPVSRKEPPLT---PVPLKRAEFAGDDVQVE-----STEEEQES-------GAMEFEDGDFDEPMEVEEVDLEPMAAKAWDKESEP---AEEVKQEADSGKGTVSYLGSFLPDVSCWDIDQEGDSSFSVQEVQVDSSHLPLVKGADEEQVFHFYWLDAYEDQYNQPGVVFLFGKVWIESAETHVSCCVMVKNIERTLYFLPREMKIDLNTGKETGTPISMKDVYEEFDEKIATKYKIMKFKSKPVEKNYAFEIPDVPEKSEYLEVKYSAEMPQLPQDLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKS-PPLNQPVSWCKVEAMALKPDLVNVIKDVSPPPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAAPKPPFQSHFCVVSKPKDCIFPYAFKEVIEKK---NVK--VEVAATERTLLGFFLAKVHKIDPDIIVGHNIYGFELEVLLQRINVCKAPHWSKIGRLKRS-NMPKLGGRSG--FGERNATCGRMICDVEISAKELIRCKSYHLSELVQQIL----KTERVVIPMENIQNMYSESSQLLYLLEHTWKDAKFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKK-GRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRV-------ASEAQKVTEDGEQEQIPELPDPSLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKEMVQ--------KMN----LEVIYGDTDSIMINTNSTNL---EEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAAL--VVEPTSDGNYVTKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQ-SRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKKSLPHVHVALWINSQGG--RKVKAGDTVSYVICQDGSNLTASQRAYAPEQL-----QKQDNLTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDPTQFRVHHYHKDEENDALLGGPAQLTDEEKYRDCERFKCPCPTCGTENIYDNVFDGSGTDMEPSLYRCSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICE--------EPTCRNRTRHLPLQFSRTGPL-CPACMKATLQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTPKVLQDYRKLKNTAEQFLSRSGYSEVNLSKLFA 1455

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BLAST of DNA polymerase vs. Ensembl Human
Match: POLD1 (DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175])

HSP 1 Score: 187.578 bits (475), Expect = 1.964e-47
Identity = 187/659 (28.38%), Postives = 312/659 (47.34%), Query Frame = 2

Query: 1721 NERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGR-------LKRSIALPKITGHSNTSWIERMATAGRLLCDV-EVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDR---CKYLSVGDTDQAMHILM--DLSHKSVAKPPGILPIEIRKLVEARNAVK-QLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKG-IQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAG-GSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
             E  L+      +  +DPD+I G+ +  + L  L+ R Q L + T+   GR       ++ S    K TG  +T  +   +  GR+  D+ +V  RE  K RSY    +    L E+ +    S+ + DL    + +   ++L    L ++ + + L+  L VL  A+E+  + G  +   LS G+  +    LL     +  ++P                   +GG+       Y G  V+EP KG Y+  I  +DF+SLYPSI++ +N+C+TT+ R    + L + + DQ +      +    SV K  G+LP  +  L+ AR   K +L    +  + ++L  D RQ ALK++ANS+YG  G    +    +++  VT  GR+++  TK+++E   +K + +   + +  ++YGDTDSVM   G+ +V +    M +G+   + V+  +   I+L  + V    LL++KK+YA L   SR  +  ++    + KGL+ VRRD C L       ++T  L   L   D   ++ +    ISD + N +I + + +ITK LTR   +Y+  Q   HV++A R+     GS       D V Y+I +      A  ++  P  VL      E  L ID  YYL  QL   + R+ EPI
Sbjct:  373 KEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSNIRDSSFQSKQTGRRDTKVV---SMVGRVQMDMLQVLLREY-KLRSYTLNAVSFHFLGEQKEDVQHSI-ITDLQNGNDQTR--RRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMP---------------VVKSEGGE------DYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGTAQKLGLTE-DQFIRTPTGDEFVKTSVRK--GLLPQILENLLSARKRAKAELAKETDPLRRQVL--DGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVE---SKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAE---AMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRM----DCKGLEAVRRDNCPLVAN----LVTASLRRLLIDRDPEGAVAHAQDVISDLLCN-RIDISQLVITKELTRAASDYAGKQA--HVELAERMRKRDPGSAPSL--GDRVPYVIISAAKGVAAYMKSEDPLFVL------EHSLPIDTQYYLEQQLAKPLLRIFEPI 973

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Query: 1721 NERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGR-------LKRSIALPKITGHSNTSWIERMATAGRLLCDV-EVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDR---CKYLSVGDTDQAMHILM--DLSHKSVAKPPGILPIEIRKLVEARNAVK-QLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKG-IQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAG-GSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
             E  L+      +  +DPD+I G+ +  + L  L+ R Q L + T+   GR       ++ S    K TG  +T  +   +  GR+  D+ +V  RE  K RSY    +    L E+ +    S+ + DL    + +   ++L    L ++ + + L+  L VL  A+E+  + G  +   LS G+  +    LL     +  ++P                   +GG+       Y G  V+EP KG Y+  I  +DF+SLYPSI++ +N+C+TT+ R    + L + + DQ +      +    SV K  G+LP  +  L+ AR   K +L    +  + ++L  D RQ ALK++ANS+YG  G    +    +++  VT  GR+++  TK+++E   +K + +   + +  ++YGDTDSVM   G+ +V +    M +G+   + V+  +   I+L  + V    LL++KK+YA L   SR  +  ++    + KGL+ VRRD C L       ++T  L   L   D   ++ +    ISD + N +I + + +ITK LTR   +Y+  Q   HV++A R+     GS       D V Y+I +      A  ++  P  VL      E  L ID  YYL  QL   + R+ EPI
Sbjct:  373 KEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSNIRDSSFQSKQTGRRDTKVV---SMVGRVQMDMLQVLLREY-KLRSYTLNAVSFHFLGEQKEDVQHSI-ITDLQNGNDQTR--RRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMP---------------VVKSEGGE------DYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGTAQKLGLTE-DQFIRTPTGDEFVKTSVRK--GLLPQILENLLSARKRAKAELAKETDPLRRQVL--DGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVE---SKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAE---AMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRM----DCKGLEAVRRDNCPLVAN----LVTASLRRLLIDRDPEGAVAHAQDVISDLLCN-RIDISQLVITKELTRAASDYAGKQA--HVELAERMRKRDPGSAPSL--GDRVPYVIISAAKGVAAYMKSEDPLFVL------EHSLPIDTQYYLEQQLAKPLLRIFEPI 973

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BLAST of DNA polymerase vs. Ensembl Celegans
Match: pola-1 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:C7IVS4])

HSP 1 Score: 555.444 bits (1430), Expect = 1.019e-172
Identity = 402/1167 (34.45%), Postives = 617/1167 (52.87%), Query Frame = 2

Query:  941 IYWFDAYHD-KKIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPK-------DQAQMTEVYSEVKSILA-KHGIESLRTKPVTKKY----AFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXS-----PPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQN--NFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEML-PEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNP-NLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQHNEADNTYSKQESTDEANRFIDCKPLPIYC--RKCQH----KTSIDFKMELEKPWL----CGNCNVELLYSHADAV---NVNKKLKEIIDRIIHIYYSCIS-TCQCGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLL---TGKENLSYKQKEL--------------LQMCSKYVERVLERSDYMNVDFKSLMA 4282
            +YW DAY D  K  G V+LFGK +  S   +    I V  + R++Y +P+       +++ + E++ E+  +L  K      + K V K+     +F +     ++  + V Y ++  +LPSDL G TFS  F  + + LE  +++ +  GP W+          + S CK  FE+   K   I+  +S     P   +L+LN+ T +N++ + NEI  I    + +   D A PS   ++     ++T P    +PYD+ ++L +E  + +  SV   ANE++L++  L  ++  +PD+IVGH L    + +L+ R + L +  W +  RLKRSI + KI GHS +   E   TAGR++ D +++A EL+K RS++  +L Q++L  E+ + + + +P      L+  S  +  LI+ + ++ L+++ ++  L  LPL ++I+ I G +  RT+ GG++ERNEYLLLHAF +   I PDK      +   +  + +++G +    K  Y+GGLVLEPKKGLYE  ILL+DFNSLYPSII EYNIC+TT++  K     D+D+       LS        G+LP EIRKLVE R  VK L+ +  N +K+K  Q DIRQ ALK+TANSMYGCLGF  SRF A  LAALVT  GREIL+++K ++E             +   ++YGDTDS+M+NT   N        K+G  IK+ VN+ ++ ++L++DGV +R+LLL KKKYA+L +    K   K     ELKGLDIVRRDW +L+ E G  ++  IL+  L+ +++  SI + L+ I   + +  + L  F I+K LTRNPE Y++ + Q H  VA R+N +G      R  D VEY+IC DGT   ATQRAY   E+      E   L ID  YYLA Q+HPVV RL+EPI+  DA  +AE+LGLD + Y  A     +     +  +  + N  + C+ + + C    C H    + + D   +   P L    C  C          AV    V++++ E + R     + C   TC+     + M   C E             C RC +G+++   +S  L  Q  ++R +L        LS  QK+               + +  +  E+ LE++ Y  VD   + A
Sbjct:  328 MYWIDAYEDVHKANGTVYLFGKVK-TSGNAWETCSIVVKNICRKVYFMPRTKNLSTGEESSLAELHKEIGDVLRNKFNTHEFKCKMVEKELIRDESFGY-GCGTKSPLMEVLYPAEKGKLPSDLKGDTFSNTFNTSVTPLERLLIEKKFMGPGWIELYNYSDPKAKTSNCKYEFEVDMEKMRNIKYLESSDAPPPTIKLLALNVVTTLNDRKD-NEICMISMLFNPKC--DLAHPSGDSKDLKPKCLVTKPPGGSLPYDIQKRLETEKLSKFVKSV---ANEKALLTLFLAMINEDEPDMIVGHDL-SATIALLVSRLEKLKLPNWSRISRLKRSINIGKI-GHSKSGQWE--LTAGRMMLDSKLAAMELVKSRSFDLTELSQQILGAERREIYANEIP-----QLYVDSKDLISLINWSWNDLLLSLRIVVRLNALPLYIQISQIVGGIASRTMMGGRAERNEYLLLHAFEKADLIAPDK---YNSSESKKKKEESQEGDEKKSGKAQYSGGLVLEPKKGLYETLILLLDFNSLYPSIIQEYNICYTTLEYSK-----DSDE------QLSVPQSTDIEGVLPREIRKLVECRRDVKSLMKSERNEAKKK--QMDIRQMALKLTANSMYGCLGFQYSRFYAKPLAALVTAKGREILMHSKDLVE------------KMGYSVVYGDTDSIMINT---NSVDLVAAKKLGNEIKKAVNKCHRLLELDLDGVFKRMLLLKKKKYAALTINPDTKVEAK-----ELKGLDIVRRDWSQLAKETGTAVVDKILDASLTRDEMVSSIDDLLREIRAKLDSGTVPLEMFQISKQLTRNPEQYADVKAQCHAAVAQRLNKSGKF--NLRHNDIVEYVICEDGTDNPATQRAYHRTEM-----AENSALKIDLLYYLAQQIHPVVSRLVEPIEETDAVRIAENLGLDSTNYRRAAAAQASQRAAEEDCAWHQENYDL-CEGIHVICPLDGCGHSNVIRETFDCVTDASSPRLLFSGCAQCQGSWDLQEHQAVIGNQVDRQMSEFVARHHLAAFKCDEPTCEFKTRVQTM-KWCRE----------GLECIRCSTGVLRREYTSKQLFDQQMFFRTILDVDAAVRKLSDAQKKAAKVRVEYNGCKIDSMMLADRINEKYLEKNAYNRVDLSYIFA 1422

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BLAST of DNA polymerase vs. Ensembl Celegans
Match: pola-1 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:C7IVS4])

HSP 1 Score: 553.903 bits (1426), Expect = 7.866e-172
Identity = 403/1156 (34.86%), Postives = 613/1156 (53.03%), Query Frame = 2

Query:  941 IYWFDAYHD-KKIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPK-------DQAQMTEVYSEVKSILA-KHGIESLRTKPVTKKY----AFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXS-----PPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQN--NFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEML-PEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNP-NLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQHNEADNTYSKQESTDEANRFIDCKPLPIYC--RKCQH----KTSIDFKMELEKPWL----CGNCNVELLYSHADAV---NVNKKLKEIIDRIIHIYYSCIS-TCQCGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLL---TGKENLSYKQKE--LLQMCSKYVERVLERSDYMNVDFKSLMAK 4285
            +YW DAY D  K  G V+LFGK +  S   +    I V  + R++Y +P+       +++ + E++ E+  +L  K      + K V K+     +F +     ++  + V Y ++  +LPSDL G TFS  F  + + LE  +++ +  GP W+          + S CK  FE+   K   I+  +S     P   +L+LN+ T +N++ + NEI  I    + +   D A PS   ++     ++T P    +PYD+ ++L +E  + +  SV   ANE++L++  L  ++  +PD+IVGH L    + +L+ R + L +  W +  RLKRSI + KI GHS +   E   TAGR++ D +++A EL+K RS++  +L Q++L  E+ + + + +P      L+  S  +  LI+ + ++ L+++ ++  L  LPL ++I+ I G +  RT+ GG++ERNEYLLLHAF +   I PDK      +   +  + +++G +    K  Y+GGLVLEPKKGLYE  ILL+DFNSLYPSII EYNIC+TT++  K     D+D+       LS        G+LP EIRKLVE R  VK L+ +  N +K+K  Q DIRQ ALK+TANSMYGCLGF  SRF A  LAALVT  GREIL+++K ++E             +   ++YGDTDS+M+NT   N        K+G  IK+ VN+ ++ ++L++DGV +R+LLL KKKYA+L +    K   K     ELKGLDIVRRDW +L+ E G  ++  IL+  L+ +++  SI + L+ I   + +  + L  F I+K LTRNPE Y++ + Q H  VA R+N +G      R  D VEY+IC DGT   ATQRAY   E+      E   L ID  YYLA Q+HPVV RL+EPI+  DA  +AE+LGLD + Y  A     +     +  +  + N  + C+ + + C    C H    + + D   +   P L    C  C          AV    V++++ E + R     + C   TC+     + M   C E             C RC +G+++   +S  L  Q  ++R +L        LS  QK   L     K  E+ LE   +     K+  AK
Sbjct:  328 MYWIDAYEDVHKANGTVYLFGKVK-TSGNAWETCSIVVKNICRKVYFMPRTKNLSTGEESSLAELHKEIGDVLRNKFNTHEFKCKMVEKELIRDESFGY-GCGTKSPLMEVLYPAEKGKLPSDLKGDTFSNTFNTSVTPLERLLIEKKFMGPGWIELYNYSDPKAKTSNCKYEFEVDMEKMRNIKYLESSDAPPPTIKLLALNVVTTLNDRKD-NEICMISMLFNPKC--DLAHPSGDSKDLKPKCLVTKPPGGSLPYDIQKRLETEKLSKFVKSV---ANEKALLTLFLAMINEDEPDMIVGHDL-SATIALLVSRLEKLKLPNWSRISRLKRSINIGKI-GHSKSGQWE--LTAGRMMLDSKLAAMELVKSRSFDLTELSQQILGAERREIYANEIP-----QLYVDSKDLISLINWSWNDLLLSLRIVVRLNALPLYIQISQIVGGIASRTMMGGRAERNEYLLLHAFEKADLIAPDK---YNSSESKKKKEESQEGDEKKSGKAQYSGGLVLEPKKGLYETLILLLDFNSLYPSIIQEYNICYTTLEYSK-----DSDE------QLSVPQSTDIEGVLPREIRKLVECRRDVKSLMKSERNEAKKK--QMDIRQMALKLTANSMYGCLGFQYSRFYAKPLAALVTAKGREILMHSKDLVE------------KMGYSVVYGDTDSIMINT---NSVDLVAAKKLGNEIKKAVNKCHRLLELDLDGVFKRMLLLKKKKYAALTINPDTKVEAK-----ELKGLDIVRRDWSQLAKETGTAVVDKILDASLTRDEMVSSIDDLLREIRAKLDSGTVPLEMFQISKQLTRNPEQYADVKAQCHAAVAQRLNKSGKF--NLRHNDIVEYVICEDGTDNPATQRAYHRTEM-----AENSALKIDLLYYLAQQIHPVVSRLVEPIEETDAVRIAENLGLDSTNYRRAAAAQASQRAAEEDCAWHQENYDL-CEGIHVICPLDGCGHSNVIRETFDCVTDASSPRLLFSGCAQCQGSWDLQEHQAVIGNQVDRQMSEFVARHHLAAFKCDEPTCEFKTRVQTM-KWCRE----------GLECIRCSTGVLRREYTSKQLFDQQMFFRTILDVDAAVRKLSDAQKSSCLRNFIGKKWEKSLENGKFRRNSAKNQAAK 1411

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BLAST of DNA polymerase vs. Ensembl Celegans
Match: F10C2.4 (DNA polymerase delta catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P90829])

HSP 1 Score: 184.111 bits (466), Expect = 9.301e-47
Identity = 178/651 (27.34%), Postives = 307/651 (47.16%), Query Frame = 2

Query: 1721 NERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATA----GRLLCDV-EVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYK-GIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRIN--SAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
            NE+ L+      +  +DPDII G+ ++ + L  +L R + L++      GR K   ++ +    S+     R+  +    GR++ DV +V  R+  K RSY    +  + L E+ K  V    + DL          ++L    L ++ + + L+ +L  +   +E+  + G  +   L+ G+  +   ++L    +  + +P           +E +  + +G         Y G  V++P +G Y   I  +DF SLYPSI++ +N+C+TT+   K     + +  +         + +K  G+LP  +  ++ AR   K  + N    + K + ++ RQ ALKI+ANS+YG  G +  +    +++  VT  GR+++  TK  +E    K +          +IYGDTDSVMV  G+  V Q    M+IG    +EV++ +   I+L  + V    LL+NKK+YA L     D        K + KGL+ VRRD C L      ++L + LE+ L   D   ++    ++ISD + N KI +   II+K LT++ + Y   Q   HV++A R+    AG +    R  D V Y+      +  A +RA  P  VL ++      + +D  +YL +QL   + R+ EPI
Sbjct:  343 NEKVLLEKWAEFVREVDPDIITGYNILNFDLPYILDRAKVLSLPQVSHLGRQKEKGSVVRDAAISSKQMGSRVNKSIDIHGRIIFDVLQVVLRDY-KLRSYTLNSVSYQFLSEQ-KEDVEHNIIPDLQR--GDEQTRRRLAQYCLKDAYLPLRLLDKLMSIINYIEMARVTGVPMNFLLTKGQQIKILSMMLRRCKQNNFFLP----------VIEANSGDGEG---------YEGATVIDPIRGFYNEPIATLDFASLYPSIMIAHNLCYTTL--LKSPQGVENEDYIRTPSGQYFATKSKRRGLLPEILEDILAARKRAKNDMKNEK-DEFKRMVYNGRQLALKISANSVYGFTGATVGKLPCLEISQSVTAFGRKMIDMTKLEVERIYKKGALDGKCPADAKVIYGDTDSVMVKFGVETVAQ---AMEIGLDAAKEVSKIFTPPIKLEFEKVYSPYLLINKKRYAGLYFTKPDVHD-----KMDCKGLETVRRDNCPLV----AKVLGVCLEKLLIERDQQSALDFAKRTISDLLCN-KIDISLLIISKELTKSGDKYQAKQA--HVELAARMKKRDAGSAP---RLGDRVPYVFVAAAKNVPAYERAEDPTFVLQNN------IPLDTKHYLTNQLAKPLARIFEPI 943

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BLAST of DNA polymerase vs. Ensembl Celegans
Match: rev-3 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AX87])

HSP 1 Score: 102.449 bits (254), Expect = 1.663e-21
Identity = 130/542 (23.99%), Postives = 223/542 (41.14%), Query Frame = 2

Query: 1769 DPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATA-----GRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLI-----DLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTI----------------------DRCKYLSVGDTDQAMHILMDLSHKSVAKPP------------GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQH--DIRQKALKITANSMYGCLGFSQS-RFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEV-NRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEE 3250
            D D+++G+  I    G   +R + L         R+    AL  I  + +   ++          GRLL  V    R  +  R+Y+    +  +L +K       +P+ D   L     G +  I        L  S +NI L+ E+       E+  + G       + G   R E +LL   +   ++ P     L +N     +Q                  L+LEP+  +Y + ++++DF SLYPS+++ YN C++TI                         KY    D      I+  +++K V   P            G++P+ +R+++ AR  VK  +     +K K L+   D RQ ALK+ AN  YG    + S R    +LA  +   GRE L  + ++++ G              ++IYGDTDS+ V     +V   +   +IG+ I ++V N     + L ++ V +  +L  KK+YA   +   +   G L    + KG++ VRRD C +  EV ++ L +I  +
Sbjct:  598 DVDVMIGYETIRLSWGFFFRRIKLLG-------SRISMDRAL--IDAYEDHIEVDDQEITVAPPKGRLLVSVWKVVRSDLALRNYDLGSAVANVLRKK-------IPMLDNAALMRRIKGERSAIRNDVHLHLLKLSSLNISLLTEMNWFLKNAEMARVYGIQFHEVWTRGSQLRVESMLLRLAHRMNFVAP-SITHLQRNMMGSPEQLQ----------------LILEPQSKVYFDPVIVLDFQSLYPSMVIAYNYCYSTILGKIGNLVQMNDESRNREEIVLGAIKYHPSKD-----DIVKLVAYKEVCASPLASMFVKKSKREGVMPLLLREILAARIMVKSAMKR---TKNKKLKRILDARQLALKLVANVSYGYTAANWSGRMPCAELADAILGKGRETLERSIEMVQRGDYG---------GAEVIYGDTDSMFVLVRGASV---EEAFEIGRRIVDDVTNSNPDPVVLKLEKVYKGCVLETKKRYAGW-MYEHENDEGSL----DAKGIETVRRDTCPIVAEVLEKSLGLIFSQ 1081

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BLAST of DNA polymerase vs. Ensembl Celegans
Match: rev-3 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AX87])

HSP 1 Score: 100.523 bits (249), Expect = 5.404e-21
Identity = 130/542 (23.99%), Postives = 223/542 (41.14%), Query Frame = 2

Query: 1769 DPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATA-----GRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLI-----DLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTI----------------------DRCKYLSVGDTDQAMHILMDLSHKSVAKPP------------GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQH--DIRQKALKITANSMYGCLGFSQS-RFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEV-NRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEE 3250
            D D+++G+  I    G   +R + L         R+    AL  I  + +   ++          GRLL  V    R  +  R+Y+    +  +L +K       +P+ D   L     G +  I        L  S +NI L+ E+       E+  + G       + G   R E +LL   +   ++ P     L +N     +Q                  L+LEP+  +Y + ++++DF SLYPS+++ YN C++TI                         KY    D      I+  +++K V   P            G++P+ +R+++ AR  VK  +     +K K L+   D RQ ALK+ AN  YG    + S R    +LA  +   GRE L  + ++++ G              ++IYGDTDS+ V     +V   +   +IG+ I ++V N     + L ++ V +  +L  KK+YA   +   +   G L    + KG++ VRRD C +  EV ++ L +I  +
Sbjct:  314 DVDVMIGYETIRLSWGFFFRRIKLLG-------SRISMDRAL--IDAYEDHIEVDDQEITVAPPKGRLLVSVWKVVRSDLALRNYDLGSAVANVLRKK-------IPMLDNAALMRRIKGERSAIRNDVHLHLLKLSSLNISLLTEMNWFLKNAEMARVYGIQFHEVWTRGSQLRVESMLLRLAHRMNFVAP-SITHLQRNMMGSPEQLQ----------------LILEPQSKVYFDPVIVLDFQSLYPSMVIAYNYCYSTILGKIGNLVQMNDESRNREEIVLGAIKYHPSKD-----DIVKLVAYKEVCASPLASMFVKKSKREGVMPLLLREILAARIMVKSAMKR---TKNKKLKRILDARQLALKLVANVSYGYTAANWSGRMPCAELADAILGKGRETLERSIEMVQRGDYG---------GAEVIYGDTDSMFVLVRGASV---EEAFEIGRRIVDDVTNSNPDPVVLKLEKVYKGCVLETKKRYAGW-MYEHENDEGSL----DAKGIETVRRDTCPIVAEVLEKSLGLIFSQ 797

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BLAST of DNA polymerase vs. Ensembl Fly
Match: DNApol-alpha180 (gene:FBgn0259113 transcript:FBtr0084115)

HSP 1 Score: 676.781 bits (1745), Expect = 0.000e+0
Identity = 443/1177 (37.64%), Postives = 653/1177 (55.48%), Query Frame = 2

Query:  932 LKLIYWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLP-------------KDQAQMTEVYSEVKSILAKH-GIESLRTKPVTKKYAFQFI--DVPDETDYLMVQYDSK--FPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPPFSILSL-----NIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEAN-ERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQ--SNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQHNEADNTYSKQ-----ESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELEKPWLCGNCNVELLYSHADA----------VNVNKKLKEIIDRIIHIYYSCISTC---QCGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLLT-GKENLSYKQ------KELLQMCSKYVERVLERSDYMNVDFKSLMAKFSRQIKI 4306
            L+  YW +AY D  K+PG VFLFG+T D  +     VC+RV  + R +Y+LP             K +  + ++Y E  S +A    +E  R++ VTK +A   I  +VP   DYL V YD K   P L +D    + + IFGA T+ LE F+LD ++KGPCWL  +G + S    S C     +   K +++ ++K  P     L     N++T MN K++ NEI  I    HN  ++DR  P   F  +   LT P     P DLN ++A      YK++ + + + ER+L+S  L +   +D D+IV    +  QL ++  +  AL I  W + GRL+ S +  K         +E     GR++CDV+ SA E I+ RSY+ + L +++L  K ++    V   DL  ++     I +LI LT+ ++   + LM EL ++PLAL+IT ICGN + RTL GG+SERNE+LLLHAF+EK YIVPDK     ++   + D   S       +K+K  YAGGLVLEP +GLYE ++LLMDFNSLYPSII EYNICFTT+ +       D D+ +  L D   +     PGILP+++++LVE+R  VK+L+  P+LS E  +Q+ IRQ ALK+TANSMYGCLGF+ SRF A  LAALVT  GREIL NT+++++        K+N     D++YGDTDS+M+NT   N+  YD V KIG  IK+ VN+ YK ++L+IDGV   +LLL KKKYA++  +S+D S G L  +QE KGLDIVRRDW +L++ VGK +L  +L E+   E L  ++H  L+ I   +    + L  F+ITK LTR P+ Y+N    PHVQVALR+N      ++Y+  D V+Y+IC DGT+  A QRAY   E+ +S   E++KL +D NYYL HQ+HPVV R++E ++  DAS +AE LG+DP+K+    Q  + +NT   +     ++T +  R   C+P    C  C+ +          +P    N ++ +L   A +           +V  +L+  + + +  +Y     C    C +         N     L   + +  C +C SG +    +   L  QL Y RF+   GK+ L  K       ++  Q+  + V++ L+ S Y+ +    L A+   Q+ +
Sbjct:  362 LRFWYW-EAYEDPVKMPGEVFLFGRTADGKS-----VCLRVQNINRVLYLLPRQFLLDPISKEPTKQKVTVADIYKEFDSEVANQLKLEFFRSRKVTKSFAHHAIGIEVPQSCDYLEVHYDGKKPLPNLSADKKYNSIAHIFGATTNALERFLLDRKIKGPCWLQVTGFKVSPTPMSWCNTEVTLTEPKNVELVQDKGKPAPPPPLTLLSLNVRTSMNPKTSRNEICMISMLTHNRFHIDRPAPQPAFNRHMCALTRPAVVSWPLDLNFEMA-----KYKSTTVHKHDSERALLSWFLAQYQKIDADLIVTFDSMDCQLNVITDQIVALKIPQWSRMGRLRLSQSFGK-------RLLEHFV--GRMVCDVKRSAEECIRARSYDLQTLCKQVLKLK-ESERMEVNADDLLEMYEKGESITKLISLTMQDNSYLLRLMCELNIMPLALQITNICGNTMTRTLQGGRSERNEFLLLHAFHEKNYIVPDKKPVSKRSGAGDTDATLSGADATMQTKKKAAYAGGLVLEPMRGLYEKYVLLMDFNSLYPSIIQEYNICFTTVQQ-----PVDADE-LPTLPDSKTE-----PGILPLQLKRLVESRKEVKKLMAAPDLSPELQMQYHIRQMALKLTANSMYGCLGFAHSRFFAQHLAALVTHKGREILTNTQQLVQ--------KMN----YDVVYGDTDSLMINT---NITDYDQVYKIGHNIKQSVNKLYKQLELDIDGVFGCLLLLKKKKYAAIK-LSKD-SKGNLRREQEHKGLDIVRRDWSQLAVMVGKAVLDEVLSEKPLEEKLD-AVHAQLEKIKTQIAEGVVPLPLFVITKQLTRTPQEYANSASLPHVQVALRMNRERN--RRYKKGDMVDYVICLDGTTNAAMQRAYHLDELKTS---EDKKLQLDTNYYLGHQIHPVVTRMVEVLEGTDASRIAECLGMDPTKFRQNAQRTQRENTEQSEGESLLKTTLQLYRL--CEPFRFQCVTCKTE---QLMASAYRPG-PSNSHIAVLQQCAKSECQTAPIQYLASVRNQLQLSMRQYVQRFYKNWLVCDHPDCNF---------NTRTHSLRKKSHRPLCQKCRSGSLLRQYTERDLYNQLCYLRFMFDLGKQTLQQKPTLTPELEQAYQLLYETVDQQLQSSSYVIISLSKLFARSLAQMSL 1468

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BLAST of DNA polymerase vs. Ensembl Fly
Match: DNApol-delta (gene:FBgn0263600 transcript:FBtr0075522)

HSP 1 Score: 182.57 bits (462), Expect = 4.079e-46
Identity = 181/672 (26.93%), Postives = 295/672 (43.90%), Query Frame = 2

Query: 1700 NSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLK--RSIALPKITGHSNTSWIERMAT--AGRLLCDVEVSARELIKCRSYE----QRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP------------GILPIEIRKLVEARNAVKQLLN-NPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRY-KGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
            + VL    E  ++      +  +DPDI+ G+ +  +    LL R   L +  +   GR+K  RS+   ++         E       GR+  D+        K RSY         +QE   +   + ++ +  GD  T        ++L    L ++ + + L+ +L  +   +E+  + G  +   L+ G+  +    LL     K +I+P   +            S+EQ          Y G  V+EPK+G Y + I  +DF SLYPSI++ +N+C+TT      L +G T + +    +L    V + P            G+LP  +  L+ AR   K  L    +  K K+L  D RQ ALKI+ANS+YG  G    +    +++  VT +GR ++  TK  +E    + +   N  V   +IYGDTDSVMVN G+  +   +  M++G+   E V+ ++   I+L  + V    LL+NKK+YA L     D        K + KG++ VRRD   L   +    L  +L E      +A     Y+K +  D+   +I +   +ITK L +   +Y+  Q    +   ++    G + K     D V Y+IC    +  A Q+A  P  VL +S      + ID  YYL  QL   + R+ EPI
Sbjct:  350 SQVLCHDKETQMLDKWSAFVREVDPDILTGYNINNFDFPYLLNRAAHLKVRNFEYLGRIKNIRSVIKEQMLQSKQMGRRENQYVNFEGRVPFDLLFVLLRDYKLRSYTLNAVSYHFLQEQKEDVHHSIITDLQNGDEQTR-------RRLAMYCLKDAYLPLRLLEKLMAIVNYMEMARVTGVPLESLLTRGQQIKVLSQLLRKAKTKGFIMPSYTS----------QGSDEQ----------YEGATVIEPKRGYYADPISTLDFASLYPSIMMAHNLCYTT------LVLGGTREKLRQQENLQDDQVERTPANNYFVKSEVRRGLLPEILESLLAARKRAKNDLKVETDPFKRKVL--DGRQLALKISANSVYGFTGAQVGKLPCLEISGSVTAYGRTMIEMTKNEVESHYTQANGYENNAV---VIYGDTDSVMVNFGVKTL---ERSMELGREAAELVSSKFVHPIKLEFEKVYYPYLLINKKRYAGLYFTRPDTYD-----KMDCKGIETVRRDNSPLVANLMNSCLQKLLIERDPDGAVA-----YVKQVIADLLCNRIDISHLVITKELAKT--DYAAKQAHVELAAKMKKRDPGTAPK---LGDRVPYVICAAAKNTPAYQKAEDPLYVLENS------VPIDATYYLEQQLSKPLLRIFEPI 959

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BLAST of DNA polymerase vs. Ensembl Fly
Match: DNApol-zeta (gene:FBgn0002891 transcript:FBtr0088831)

HSP 1 Score: 95.9005 bits (237), Expect = 2.257e-19
Identity = 89/334 (26.65%), Postives = 155/334 (46.41%), Query Frame = 2

Query: 2393 RKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTT-IDRCKYLSVGD-----------TDQAMHILMDLSHKSVAKPP------------GILPIEIRKLVEARNAVKQ--LLNNPNLSKEKLLQHDIRQKALKITANSMYG--CLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNR-RYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSIS 3307
            R P Y   L++EP+   Y + ++++DF SLYPS+I+ YN CF+T + R ++L               + Q +  L  L H  V   P            GILP  + ++++ R  VKQ   L+  + + +++L    RQ  LK+ AN  YG     FS  R  + ++   V   GRE L    K++E+         N    + ++YGDTDS+ V     N  +     +IG+ I + V     + ++L ++ V +  +L  KK+Y      + D+         E KG++ VRRD C    ++ +++L ++ E +   +  A+    + K +S
Sbjct: 1582 RAPEYLA-LIMEPQSRFYADPLIVLDFQSLYPSMIIAYNYCFSTCLGRVEHLGGSSPFEFGASQLRVSRQMLQKL--LEHDLVTVSPCGVVFVKREVREGILPRMLTEILDTRQMVKQSMKLHKDSSALQRILHS--RQLGLKLMANVTYGYTAANFS-GRMPSVEVGDSVVSKGRETLERAIKLVEN---------NEEWKVRVVYGDTDSMFVLVPGRNRAE---AFRIGEEIAKAVTEMNPQPVKLKLEKVYQPCMLQTKKRYVGYMYETADQEQPVY----EAKGIETVRRDGCPAVAKMLEKVLRILFETQDVSKIKAYVCRQFTKLLS 1893

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BLAST of DNA polymerase vs. Ensembl Zebrafish
Match: pola1 (polymerase (DNA directed), alpha 1 [Source:ZFIN;Acc:ZDB-GENE-030114-9])

HSP 1 Score: 848.195 bits (2190), Expect = 0.000e+0
Identity = 564/1517 (37.18%), Postives = 828/1517 (54.58%), Query Frame = 2

Query:   41 DTYG----RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQ--LDNFIEGDSEYMESGKEIFDESDEEDIKIGPKRKKSMKNANL-KNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSK------------IKPNEPKEMPQKTVQEPIKFVKKQIVFN-----KGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPF----------------ETNPVVSAGFATDT----------------KLEEHKPLWETEEIEDESSNDKYDPFENIDKSSLKLIYWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ------------AQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXS-PPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQG-GKFSK--RKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQH--NEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELEKPWL------CGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL----------LTGKENLSYKQKELLQMCSKY------VERVLERSDYMNVDFKSLMAKF 4288
            DT G    R RR++  +K+ +   L +LK+AK+ G  +K E+E    IYD V+EE Y K+  +RQ       +  + Y+E G+EIFDE  ++D  +GPK K++ K  +  KN KK+ +       +S KS+F                   +   +LS   ++++    L     E    +  P +I+  K            +KP  PKE+P+  V +P   V +    +       S E +K+ +  +  +   +   E+ I  D++DFDEP                 ET P+V     T+                 K+EE KP+    E++ +SS  +    E  D   +   YW DA+ D+   PGVVFLFGK   ES +  V+ C+ V  +ER +Y+LP++               M +VY E   I  K  I   ++KPVTK YAF+  D+P +++YL V+Y ++ P LPSDL G TFS +FG NTS LE F+L+ +++GPCWL  +  + S+   S CK+    +    I + K+ S PP  ++S+++KTV N K++ NEIV+I   +H+   LD+APP   FQ +F +++ P D V PYD    +  + G      V I   ER+L+   L K+H +DPD++VGH + G+ L +LLQR     +  W K GRL+R+  +PK+ G S   + E+ AT GRL+CD+E+SA+ELI+C+SY   +L+ ++L    KA    VP  ++   ++ S  +  L++LT  ++ + + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF+E+ +IVPDK         L  D+  + G GK +K  +K  YAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT++R    +   T++    + +L  +S+    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++             + L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L V    +  GK   KQELKGLDIVRRDWC L+ E G  ++  IL ++ + + +  +I  +L  I + + N  I L  F I K+LT+ P++Y + +  PHV VAL INS GG  K+ +A DTV Y+IC DG++  A+QRAY+ +++      ++  L++D  YYL+ Q+HPVV R+ EPI+ IDA  +A  LGLDPS +    Q   +EAD+         +  R+ DC+     C  C  +   D   E     L      C  C+V    S  D  V +  KL+  I R I  YYS    C+           C    R+L +   +    CP C    +KP  S   L  QL +YR++          LTG + L +K KE  +    Y       + +L  S Y  V+   L   F
Sbjct:   20 DTCGIAASRSRREKK-EKVGRKSALEQLKRAKK-GEKVKYEVEEFTSIYDEVDEEQYSKIVRERQDDDWIIDDDGTGYVEDGREIFDEELDDD-ALGPKSKQAAKGGDSKKNVKKSSVS----KPNSIKSMF----------MNSNVKKPAEKHVDLS---QDDLLGDILQDLHSEKSVVLTPPPIITLKKKKTLGSPMNPFSVKPQMPKELPEVHVSKPRPVVTRVPPADPSPRSAASVEPSKA-TAAQIKKPKIEEPEEEAIEFDEMDFDEPMEAENLEEEPVKEKAEPETKPIVKVEPKTEPQDKMLISGLVGGMGWEKMEEGKPIETPVEVQVDSS--QLPLVEGPDGDMVFRFYWLDAFEDQYNQPGVVFLFGKVWIESAEAHVSCCVAVKNIERTMYLLPREHKVNLATGEKGVAVGMMDVYKEFNEISEKFKIMKFKSKPVTKNYAFEIPDIPSQSEYLEVKYSAEIPSLPSDLKGTTFSHVFGTNTSSLEHFLLNRKIRGPCWLDVTTPQLSNQPISWCKVEAVAQKSDLISVVKDLSPPPLVVMSISLKTVQNPKTHQNEIVSIAALVHHTFPLDKAPPRPPFQTHFCVVSKPNDCVFPYDFKDAVRKKNGI-----VEIAGTERALLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLRRA-NMPKLGGRS--GFAEKSATCGRLVCDIEISAKELIRCKSYNLTELVSQIL----KAERPVVPPENIRNFYSDSTHLLYLLELTWMDAKLILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFHERDFIVPDKQFFKKAQQDLGEDEEGDSGKGKSNKTRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVERGATNTRKKTEEDEDEIPELPDQSLEM--GILPKEIRKLVERRRQVKQLMKEPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKEMVQ------------RMNLEVIYGDTDSIMINTNSTNL---EEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALMV--EPQGDGKYTTKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQ-NRDTIIENIQKHLIEIGEKVANGNIPLNMFEIHKSLTKEPQDYPDKKSLPHVHVALWINSQGG--KKVKAGDTVSYVICQDGSNLAASQRAYTLEQL-----QKQPGLNLDTQYYLSQQVHPVVGRICEPIEGIDAVLIATWLGLDPSHFRAQQQQREDEADDFLGAPAQLTDEERYRDCERFTFTCPDCGTENIYDNVFEGTGSTLQLSLKSC--CHVPCGGSPMDHQVQIGNKLQLDIRRHIRRYYSGWLLCE--------DQACRNRIRRLPIAFSRSGPICPACLRSTLKPEYSEKALYNQLSFYRYIFDWEYAINKVLTGDDKLKFKSKEWKEEMEVYKKLKGVTDNILATSGYSEVNLAKLFQAF 1464

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BLAST of DNA polymerase vs. Ensembl Zebrafish
Match: pola1 (polymerase (DNA directed), alpha 1 [Source:ZFIN;Acc:ZDB-GENE-030114-9])

HSP 1 Score: 838.18 bits (2164), Expect = 0.000e+0
Identity = 560/1500 (37.33%), Postives = 824/1500 (54.93%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEG--DSEYMESGKEIFDESDEEDIKIGPKRKKSMKNANLK-NPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSKIK----PNEP----KEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFE----------------TNPVVSAGFATDT----------------KLEEHKPLWETEEIEDESSNDKYDPFENIDKSSLKLIYWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ------------AQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQG-GKFSK--RKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQH--NEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELEKPWL------CGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL----------LTGKENLSYKQKELLQMCSKY------VERVLERSDYMNVDFKSLMAKF 4288
            R RR++  +K+ +   L +LK+AK+ G  +K E+E    IYD V+EE Y K+  +RQ D++I     + Y+E G+EIFDE  ++D  +GPK K++ K  + K N KK+ +       +S KS+F                   +   +LS   ++++    L     E    +  P +I+  K K    P  P     +MP+  +  P      +   +  S E +K+ +  +  +   +   E+ I  D++DFDEP E                T P+V     T+                 K+EE KP+    E++ +SS  +    E  D   +   YW DA+ D+   PGVVFLFGK   ES +  V+ C+ V  +ER +Y+LP++               M +VY E   I  K  I   ++KPVTK YAF+  D+P +++YL V+Y ++ P LPSDL G TFS +FG NTS LE F+L+ +++GPCWL  +  + S+   S CK+    +    I + K+ SPP   ++S+++KTV N K++ NEIV+I   +H+   LD+APP   FQ +F +++ P D V PYD    +  + G      V I   ER+L+   L K+H +DPD++VGH + G+ L +LLQR     +  W K GRL+R+  +PK+ G S   + E+ AT GRL+CD+E+SA+ELI+C+SY   +L+ ++L    KA    VP  ++   ++ S  +  L++LT  ++ + + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF+E+ +IVPDK         L  D+  + G GK +K  +K  YAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT++R    +   T++    + +L  +S+    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++             + L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L V    +  GK   KQELKGLDIVRRDWC L+ E G  ++  IL ++ + + +  +I  +L  I + + N  I L  F I K+LT+ P++Y + +  PHV VAL INS GG  K+ +A DTV Y+IC DG++  A+QRAY+ +++      ++  L++D  YYL+ Q+HPVV R+ EPI+ IDA  +A  LGLDPS +    Q   +EAD+         +  R+ DC+     C  C  +   D   E     L      C  C+V    S  D  V +  KL+  I R I  YYS    C+           C    R+L +   +    CP C    +KP  S   L  QL +YR++          LTG + L +K KE  +    Y       + +L  S Y  V+   L   F
Sbjct:   28 RSRREKK-EKVGRKSALEQLKRAKK-GEKVKYEVEEFTSIYDEVDEEQYSKIVRERQDDDWIIDDDGTGYVEDGREIFDEELDDD-ALGPKSKQAAKGGDSKKNVKKSSVS----KPNSIKSMF----------MNSNVKKPAEKHVDLS---QDDLLGDILQDLHSEKSVVLTPPPIITLKKKKTLGSPMNPFSVKPQMPKVKIPIPPADPSPR---SAASVEPSKA-TAAQIKKPKIEEPEEEAIEFDEMDFDEPMEAENLEEEPVKEKAEPETKPIVKVEPKTEPQDKMLISGLVGGMGWEKMEEGKPIETPVEVQVDSS--QLPLVEGPDGDMVFRFYWLDAFEDQYNQPGVVFLFGKVWIESAEAHVSCCVAVKNIERTMYLLPREHKVNLATGEKGVAVGMMDVYKEFNEISEKFKIMKFKSKPVTKNYAFEIPDIPSQSEYLEVKYSAEIPSLPSDLKGTTFSHVFGTNTSSLEHFLLNRKIRGPCWLDVTTPQLSNQPISWCKVEAVAQKSDLISVVKDLSPPPLVVMSISLKTVQNPKTHQNEIVSIAALVHHTFPLDKAPPRPPFQTHFCVVSKPNDCVFPYDFKDAVRKKNGI-----VEIAGTERALLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLRRA-NMPKLGGRSG--FAEKSATCGRLVCDIEISAKELIRCKSYNLTELVSQIL----KAERPVVPPENIRNFYSDSTHLLYLLELTWMDAKLILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFHERDFIVPDKQFFKKAQQDLGEDEEGDSGKGKSNKTRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVERGATNTRKKTEEDEDEIPELPDQSLEM--GILPKEIRKLVERRRQVKQLMKEPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKEMVQ------------RMNLEVIYGDTDSIMINTNSTNL---EEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALMV--EPQGDGKYTTKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQ-NRDTIIENIQKHLIEIGEKVANGNIPLNMFEIHKSLTKEPQDYPDKKSLPHVHVALWINSQGG--KKVKAGDTVSYVICQDGSNLAASQRAYTLEQL-----QKQPGLNLDTQYYLSQQVHPVVGRICEPIEGIDAVLIATWLGLDPSHFRAQQQQREDEADDFLGAPAQLTDEERYRDCERFTFTCPDCGTENIYDNVFEGTGSTLQLSLKSC--CHVPCGGSPMDHQVQIGNKLQLDIRRHIRRYYSGWLLCE--------DQACRNRIRRLPIAFSRSGPICPACLRSTLKPEYSEKALYNQLSFYRYIFDWEYAINKVLTGDDKLKFKSKEWKEEMEVYKKLKGVTDNILATSGYSEVNLAKLFQAF 1452

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BLAST of DNA polymerase vs. Ensembl Zebrafish
Match: pola1 (polymerase (DNA directed), alpha 1 [Source:ZFIN;Acc:ZDB-GENE-030114-9])

HSP 1 Score: 300.056 bits (767), Expect = 1.819e-86
Identity = 181/505 (35.84%), Postives = 273/505 (54.06%), Query Frame = 2

Query:  761 LDDIDFDEPFE----------------TNPVVSAGFATDT----------------KLEEHKPLWETEEIEDESSNDKYDPFENIDKSSLKLIYWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ------------AQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXS-PPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEML--------PEKFKAFVSSVPVGDLCTLFNSSAG 2113
             D++DFDEP E                T P+V     T+                 K+EE KP+    E++ +SS  +    E  D   +   YW DA+ D+   PGVVFLFGK   ES +  V+ C+ V  +ER +Y+LP++               M +VY E   I  K  I   ++KPVTK YAF+  D+P +++YL V+Y ++ P LPSDL G TFS +FG NTS LE F+L+ +++GPCWL  +  + S+   S CK+    +    I + K+ S PP  ++S+++KTV N K++ NEIV+I   +H+   LD+APP   FQ +F       +   P   N ++AS  G++ K   L    ER+L+   L K+H +DPD++VGH + G+ L +LLQR     +  W K GRL+R+  +PK+ G S   + E+ AT GRL+CD+E+SA+ELI+C+SY   +L+ ++L        PE  + F   +P   + + F SS G
Sbjct:  238 FDEMDFDEPMEAENLEEEPVKEKAEPETKPIVKVEPKTEPQDKMLISGLVGGMGWEKMEEGKPIETPVEVQVDSS--QLPLVEGPDGDMVFRFYWLDAFEDQYNQPGVVFLFGKVWIESAEAHVSCCVAVKNIERTMYLLPREHKVNLATGEKGVAVGMMDVYKEFNEISEKFKIMKFKSKPVTKNYAFEIPDIPSQSEYLEVKYSAEIPSLPSDLKGTTFSHVFGTNTSSLEHFLLNRKIRGPCWLDVTTPQLSNQPISWCKVEAVAQKSDLISVVKDLSPPPLVVMSISLKTVQNPKTHQNEIVSIAALVHHTFPLDKAPPRPPFQTHFC------ESDTPIKNNFQIASA-GSSLKIRTLF--YERALLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLRRA-NMPKLGGRSG--FAEKSATCGRLVCDIEISAKELIRCKSYNLTELVSQILKAERPVVPPENIRNFYRLIP--HIYSTFWSSPG 726

HSP 2 Score: 56.9954 bits (136), Expect = 1.832e-7
Identity = 48/136 (35.29%), Postives = 76/136 (55.88%), Query Frame = 2

Query:   29 MSEDDTYG----RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQ--LDNFIEGDSEYMESGKEIFDESDEEDIKIGPKRKKSMKNANL-KNPKKACLDFKSIHSDSQKSLF 412
            +   DT G    R RR++  +K+ +   L +LK+AK+ G  +K E+E    IYD V+EE Y K+  +RQ       +  + Y+E G+EIFDE  ++D  +GPK K++ K  +  KN KK+ +       +S KS+F
Sbjct:    2 LDASDTCGIAASRSRREKK-EKVGRKSALEQLKRAKK-GEKVKYEVEEFTSIYDEVDEEQYSKIVRERQDDDWIIDDDGTGYVEDGREIFDEELDDD-ALGPKSKQAAKGGDSKKNVKKSSVS----KPNSIKSMF 130

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BLAST of DNA polymerase vs. Ensembl Zebrafish
Match: pold1 (polymerase (DNA directed), delta 1, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-060429-1])

HSP 1 Score: 184.882 bits (468), Expect = 1.014e-46
Identity = 187/665 (28.12%), Postives = 306/665 (46.02%), Query Frame = 2

Query: 1700 NSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGR-------LKRSIALPKITGHSNTSWIERMATAGRLLCDV-EVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTI---DRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVK-QLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRY-KGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVA--LRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
            + +L    E+ ++      +  +DPDII G+ +  + L  LL R   L +N +   GR       LK S    K  G      I      GR+  D+ +V  R+  K RSY    +    L E+ +    S+ + DL     +    ++L    L ++ + + L+ +L  +   +E+  + G  +   LS G+  +    LL    ++  ++P                   +GG+       Y G  V+EP+KG Y   I  +DF+SLYPSI++ +N+C+TT+    + + L +G  D       DL  KS  +  G+LP  +  L+ AR   K +L    +  K+++L  D RQ ALKI+ANS+YG  G    +    +++  VT  GR+++  TK+++E   ++ +          +IYGDTDSVMV  G+  V +    M  G+   E V+  +   I+L  + V    LL+NKK+YA L   S  +   K+    + KG++ VRRD C L       ++   L+  L   D   ++ +  + ISD + N +I + + +ITK LTR  + Y+  Q   HV++A  +R   AG +       D V Y+I        A  ++  P  VL      E  + ID  YYL  QL   + R+ EPI
Sbjct:  370 SQILCFTQEKLMLQSWAEFMRTVDPDIITGYNIQNFDLPYLLNRAATLKVNMFPYLGRVWGCKSVLKDSSFQSKQMGRRENKTIN---MEGRVQFDLLQVLLRDY-KLRSYTLNAVSFHFLQEQKEDVQHSI-ITDLQN--GNEQTRRRLAVYCLKDAYLPLRLLQKLMCVINYMEMARVTGVPLTYLLSRGQQIKVVSQLLRQAMKQDLVMP---------------VVKTEGGE------DYTGATVIEPEKGYYSVPIATLDFSSLYPSIMMAHNLCYTTLLQKSQIEKLGLGPDDFIKTPTGDLFVKSSVR-KGLLPEILENLLSARKRAKAELKKETDPFKKQVL--DGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEQTKQLVE---SRYTLDNGYQADAKVIYGDTDSVMVKLGVATVQE---AMNQGKEAAEWVSSHFVPPIKLEFEKVYYPYLLINKKRYAGLYFSSSAEHHDKM----DCKGIETVRRDNCPLV----ANLINTCLQNILIDRDPDGAVTHAKEVISDLLCN-RIDISQLVITKELTRTAQEYAGKQA--HVELAERMRKRDAGSAPN---LGDRVPYVIIKAAKGVAAYMKSEDPIYVL------ENNIPIDTQYYLEQQLSKPLLRIFEPI 977

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BLAST of DNA polymerase vs. Ensembl Zebrafish
Match: rev3l (REV3 like, DNA directed polymerase zeta catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-050302-55])

HSP 1 Score: 108.612 bits (270), Expect = 5.444e-23
Identity = 149/678 (21.98%), Postives = 275/678 (40.56%), Query Frame = 2

Query: 1706 VLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRL----KRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYI--VPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTT-IDRCKYLSVGDTDQ----AMHILMDLSHK---SVAKPP------------GILPIEIRKLVEARNAVKQLL----NNPNLSKEKLLQHDIRQKALKITANSMYG--CLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVN-RRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLI 3640
            V    +E+ L   + N +   DPDI+VG+ +  +  G LLQR   L +N   +  R+    +++  +P+   +   +  E +   GR++ ++    +      +Y   ++   +L +++  +        L   F++     +++D  +      + L+ +  ++    E+  + G      L+ G   R E ++L       YI   P       Q +   I                    LV+EP+   Y N ++++DF SLYPSI++ YN C++T +   + L   D  +    ++ +  DL ++    +   P            G+LP  + ++++ R  VKQ +    N+  LS  +LL  D RQ  LK+ AN  +G     FS  R    ++   +    RE L    K++ D                ++YGDTDS+ V        Q     KIG  I E V     K I+L  + V    +L  KK+Y      S D+ +       + KG++ VRRD C    ++ +R L ++ E      D++  +  Y++     +   K S+      K   R   +Y      P +++  R+ +    + + R  + V Y+I          Q    P EVL     ++  L ++  YY+  Q+ P + R+ 
Sbjct: 2208 VTYTCDEKELFEEVSNIIRKYDPDILVGYEVQMHSWGYLLQRASTLGVNLCQQLSRVPGDSQQNHFIPEKDEYGAETMTE-IHITGRIILNIWRIMKTEAALNNYTFENVAFHLLHQRYPLYSHRT----LSDWFDTHLHRWKVMDHYVSRVCGTVQLLQQQDIIGRTSELARVFGIQFYHVLTRGSQYRVESMMLRVAKPMNYIPVTPSTQQRAQQRAAQCIP-------------------LVMEPESRFYSNSVIVLDFQSLYPSIVIAYNYCYSTCLGHIENLGTYDEFKFGCASLRVPPDLLYQLRNDITVSPNGVAFVKSSVRRGVLPRMLEEILKTRIMVKQSMKAYRNDKALS--RLL--DARQLGLKLIANVTFGYTSANFS-GRMPCVEVGDSIVHKARETLERAIKMVND---------TKKWGARVVYGDTDSMFVLLKGATKEQ---AFKIGNEIAEAVTATNPKPIKLKFEKVYLPCILQTKKRYVGYMYESVDQENPVF----DAKGIETVRRDGCPGVSKILERSLKLLFES----RDIS-QVKQYVQRQCVKVVEGKASMQDLTFAKEY-RGSGSYRPGACVPALELTRRMMAFDRRL-EPRVGERVPYVIVYGSPGVPLIQLVRRPLEVL-----QDPSLRLNATYYITKQILPPLARIF 2828

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BLAST of DNA polymerase vs. Ensembl Xenopus
Match: POLA1 (polymerase (DNA directed), alpha 1, catalytic subunit [Source:NCBI gene;Acc:100379926])

HSP 1 Score: 823.543 bits (2126), Expect = 0.000e+0
Identity = 553/1533 (36.07%), Postives = 830/1533 (54.14%), Query Frame = 2

Query:   29 MSEDDTYGRPR-RQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEG--DSEYMESGKEIFDESDEEDI--------KIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSKIKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKS---PSTIENNETPE-----------QHKIEDC--IVLDDIDFDEPFETNPVVSAGFATDT----------------KLEEHKPLWETEEIEDESSNDKYDPFEN------IDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ-------------AQMTEVYSEV-KSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKA-------AALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPED-LAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY---HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSID-----FKMELEKPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL----------LTGKENLSYKQKELLQMCSKY------VERVLERSDYMNVDFKSLMAKFS 4291
            MSE  ++   R R+  ++K  + + L +LK+AK  G  +K E+E +  IY+ V+EE Y K+   RQ D++I     + Y+E G+EIFD+  E++         K  PK K ++K +++  P      F  + S  +++    +  S          +L      ++ P       P ++ KK++       P       + P  PK +P   V++P    K   + +   S  + S   P  I+N    +           Q K ED   +  DD DFDEP E + + S    + T                K+EE    + T    +ES  D+ D  E+      +D S L L+           YW DAY D+   PGVV+LFGK   E+ + +V+ C+ V  +ER +Y+LP++                M  VY E  +S+  K+ I   ++K V K YAF+  DVP  ++YL V+Y +  P+LP DL G+TFS +FG NTS LE+F+L  ++KGP WL     + SS   S CK+   +     + + K+ +PP   +LSL++KTV N K++ NEIVA+   +H++   D+APP   FQ +F +L+ P D + PYD  + +  +  AN    + I   ER+L+   L K+H +DPDIIVGH + G+ L +LLQR  +  +  W K GRL+RS+ +PK+ G S   + ER A  GR++CD E+SA+ELI+C+SY   +L+ ++L    K     +P  ++   ++ SA +  +++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF E  +IVPDK          +  +  ++ DQ+  + G+   +K  YAGGLVLEPK G Y+ FILL+DFNSLYPSII EYNICFTT+ R    S    DQ    + +L H  +    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDG+ + +LLL KKKYA+L V       GK + KQELKGLDIVRRDWC+L+ E G  +++ IL ++  P D +  +I   L  I +++ N  + + ++ I KALT++P++Y + +  PHV VA+ INS GG  ++ +A DT+ Y+IC DG++ +A+QRAY+P+++      ++  LSID  YYL+ Q+HPVV R+ EPID ID++ +A  LGLDPS++    H  Q  E D          +  ++ DC+    +C KC  +   D       +++E P L      E   S  D  + V  KL   I R I  YYS    C+           C    R++ ++  +    C  C    ++       L  QL +YRF+          ++ +E    K+K   +  + Y      V++VL +S Y  V+   L    S
Sbjct:    1 MSESGSFAASRSRREKTEKSGRKEALERLKRAKA-GEKVKYEVEEISSIYEEVDEEQYSKIVRDRQDDDWIVDDDGTGYVEDGREIFDDDLEDNALADSGKRAKGAPKDKSNVKKSSVSKPNNIKSMF--MASAVKRTTDKTVDLSKDDLLGDLLQDLKSQALPITPP-------PVITLKKKKLAGSPLNP-----FSVPPAAPKVLP---VKKPPALAKLGHLSSAAPSNNSASSFVPREIKNEPNSDLISSAPLNVKTQVKEEDTSMVEFDDGDFDEPMEEDNLESPSVVSSTIKKEEPKIKCVKEDSVKMEESS--FMTSAALNESCWDQIDEVESMTTEVQVDSSRLPLVTGADGSQVFKFYWLDAYEDQYSQPGVVYLFGKVWIETAEAYVSCCVSVKNIERTVYLLPRENRVQLSTGKDTGVPVSMMNVYQEFNESVAEKYKIMKFKSKKVEKDYAFEIPDVPASSEYLEVRYSADSPQLPQDLKGETFSHVFGTNTSSLELFLLSRKIKGPSWLEIKSPQLSSQPMSWCKVEAVVMRPDQVNVVKDLAPPPVVVLSLSMKTVQNAKTHQNEIVAMAALVHHKFPFDKAPPQPPFQTHFCVLSKPNDCIFPYDFKEAVKRK-NAN----IEIALTERTLLGFFLAKIHKIDPDIIVGHDIYGFDLEVLLQRISSCKVPFWSKIGRLRRSV-MPKLGGRSG--FAERNAACGRIICDTEISAKELIRCKSYHLSELVHQIL----KTERVLMPPENIRNAYSDSAHLLYMLENTWTDAKFILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFTENNFIVPDKPVFKKIQQTTVEDDDNMDTDQNKNKKGR---KKAAYAGGLVLEPKVGFYDKFILLLDFNSLYPSIIQEYNICFTTVQREAPTSQKGEDQEE--IPELPHSDLEM--GILPREIRKLVERRRHVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTHQGREILLHTKEMVQ--------KMN----LEVIYGDTDSIMINTNCNNL---EEVFKLGNRVKSEVNKSYKLLEIDIDGIFKSLLLLKKKKYAALTV--EPTGDGKYVTKQELKGLDIVRRDWCELAKEAGNYVISQILSDQ--PRDNIVENIQKKLTEIGENVTNGTVPISQYEINKALTKDPQDYPDKKSLPHVHVAMWINSQGG--RKVKAGDTISYVICQDGSNLSASQRAYAPEQL-----QKQENLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHHQQDEENDALLGGPSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIE-PGLKRCSKPECDASPLDYVIQVQNKLLLDIRRYIKKYYSGWLVCE--------EKTCQNRTRRVPLSFSRNGPICQACTKATLRSEYPEKALYTQLCFYRFIFDWDYALEKVVSEQERGHLKKKHFQESENLYKKLKSTVDQVLSQSGYSEVNLSKLFQTLS 1459

[Close]

BLAST of DNA polymerase vs. Ensembl Xenopus
Match: POLA1 (polymerase (DNA directed), alpha 1, catalytic subunit [Source:NCBI gene;Acc:100379926])

HSP 1 Score: 811.601 bits (2095), Expect = 0.000e+0
Identity = 538/1484 (36.25%), Postives = 814/1484 (54.85%), Query Frame = 2

Query:   50 GRPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEGDSEYMESGKEIFDESDEEDIKIGPKRKKSMKNANLKNPKKACLDFKSIH-SDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSKIKPNEPKEMPQKTVQEPIKFVKKQ----IVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVVSAGFATDTKLEEHKPLWETEEIEDESSNDKYDPFEN------IDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ----------AQMTEVYSEV-KSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAA--ALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDR----CKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPED-LAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY---HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSID-----FKMELEKPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL----------LTGKENLSYKQKELLQMCSKY------VERVLERSDYMNVDFKSLMAKFS 4291
             R RR++ ++K  + + L +LK+AK  G  +K E+E +  IY+ V+EE Y K+   RQ D++I  D   + +GK           K  PK K ++K +++  P     + KS+  + + K     LP                      TP       P ++ KK++       P       + P  PK          ++F  ++    ++FNK S+   +  S +E                DD DFDEP E + + S    + T +++ +P  +T    +ES  D+ D  E+      +D S L L+           YW DAY D+   PGVV+LFGK   E+ + +V+ C+ V  +ER +Y+LP++             M  VY E  +S+  K+ I   ++K V K YAF+  DVP  ++YL V+Y +  P+LP DL G+TFS +FG NTS LE+F+L  ++KGP WL     + SS   S CK+   +     + + K+ +PP   +LSL++KTV N K++ NEIVA+   +H++   D+APP   FQ +F +L+ P D + PYD  + +  +  AN    + I   ER+L+   L K+H +DPDIIVGH + G+ L +LLQR  +  +  W K GRL+RS+ +PK+ G S   + ER A  GR++CD E+SA+ELI+C+SY   +L+ ++L    K     +P  ++   ++ SA +  +++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF E  +IVPDK     + Q +  +   +++   K  ++K  YAGGLVLEPK G Y+ FILL+DFNSLYPSII EYNICFTT+ R     + +S+G+  + +    +L H  +    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDG+ + +LLL KKKYA+L V       GK + KQELKGLDIVRRDWC+L+ E G  +++ IL ++  P D +  +I   L  I +++ N  + + ++ I KALT++P++Y + +  PHV VA+ INS GG  ++ +A DT+ Y+IC DG++ +A+QRAY+P+++      ++  LSID  YYL+ Q+HPVV R+ EPID ID++ +A  LGLDPS++    H  Q  E D          +  ++ DC+    +C KC  +   D       +++E P L      E   S  D  + V  KL   I R I  YYS    C+           C    R++ ++  +    C  C    ++       L  QL +YRF+          ++ +E    K+K   +  + Y      V++VL +S Y  V+   L    S
Sbjct:   15 SRSRREK-TEKSGRKEALERLKRAKA-GEKVKYEVEEISSIYEEVDEEQYSKIVRDRQDDDWIVDDVLLL-TGKRA---------KGAPKDKSNVKKSSVSKPN----NIKSMFMASAVKRTTDALPI---------------------TP------PPVITLKKKKLAGSPLNP-----FSVPPAAPK----------VRFCSRKLFGFVIFNK-SALLEEDTSMVE---------------FDDGDFDEPMEEDNLESPSVVSST-IKKEEPKIKTSAALNESCWDQIDEVESMTTEVQVDSSRLPLVTGADGSQVFKFYWLDAYEDQYSQPGVVYLFGKVWIETAEAYVSCCVSVKNIERTVYLLPRENLSTGKDTGVPVSMMNVYQEFNESVAEKYKIMKFKSKKVEKDYAFEIPDVPASSEYLEVRYSADSPQLPQDLKGETFSHVFGTNTSSLELFLLSRKIKGPSWLEIKSPQLSSQPMSWCKVEAVVMRPDQVNVVKDLAPPPVVVLSLSMKTVQNAKTHQNEIVAMAALVHHKFPFDKAPPQPPFQTHFCVLSKPNDCIFPYDFKEAVKRK-NAN----IEIALTERTLLGFFLAKIHKIDPDIIVGHDIYGFDLEVLLQRISSCKVPFWSKIGRLRRSV-MPKLGGRSG--FAERNAACGRIICDTEISAKELIRCKSYHLSELVHQIL----KTERVLMPPENIRNAYSDSAHLLYMLENTWTDAKFILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFTENNFIVPDKPVFKKIQQTTDDDNMDTDQNKNKKGRKKAAYAGGLVLEPKVGFYDKFILLLDFNSLYPSIIQEYNICFTTVQREAPTSQKVSLGEDQEEIP---ELPHSDLEM--GILPREIRKLVERRRHVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTHQGREILLHTKEMVQ--------KMN----LEVIYGDTDSIMINTNCNNL---EEVFKLGNRVKSEVNKSYKLLEIDIDGIFKSLLLLKKKKYAALTV--EPTGDGKYVTKQELKGLDIVRRDWCELAKEAGNYVISQILSDQ--PRDNIVENIQKKLTEIGENVTNGTVPISQYEINKALTKDPQDYPDKKSLPHVHVAMWINSQGG--RKVKAGDTISYVICQDGSNLSASQRAYAPEQL-----QKQENLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHHQQDEENDALLGGPSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIE-PGLKRCSKPECDASPLDYVIQVQNKLLLDIRRYIKKYYSGWLVCE--------EKTCQNRTRRVPLSFSRNGPICQACTKATLRSEYPEKALYTQLCFYRFIFDWDYALEKVVSEQERGHLKKKHFQESENLYKKLKSTVDQVLSQSGYSEVNLSKLFQTLS 1371

[Close]

BLAST of DNA polymerase vs. Ensembl Xenopus
Match: POLA1 (polymerase (DNA directed), alpha 1, catalytic subunit [Source:NCBI gene;Acc:100379926])

HSP 1 Score: 795.423 bits (2053), Expect = 0.000e+0
Identity = 480/1231 (38.99%), Postives = 707/1231 (57.43%), Query Frame = 2

Query:  755 IVLDDIDFDEPFETNPVVSAGFATDT----------------KLEEHKPLW-ETEEIEDESSNDKYDPFENIDKSSLKLIYWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ-------------AQMTEVYSEV-KSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAA--ALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPED-LAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY---HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSID-----FKMELEKPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFLLTGKENLS----YKQKE-LLQMCSKYVERVLERSDYMNVDFKSLMAKFS 4291
            +  DD DFDEP E + + S    + T                K+EE   ++ E+   E +  + +       D S +   YW DAY D+   PGVV+LFGK   E+ + +V+ C+ V  +ER +Y+LP++                M  VY E  +S+  K+ I   ++K V K YAF+  DVP  ++YL V+Y +  P+LP DL G+TFS +FG NTS LE+F+L  ++KGP WL     + SS   S CK+   +     + + K+ +PP   +LSL++KTV N K++ NEIVA+   +H++   D+APP   FQ +F +L+ P D + PYD  + +  +  AN    + I   ER+L+   L K+H +DPDIIVGH + G+ L +LLQR  +  +  W K GRL+RS+ +PK+ G S   + ER A  GR++CD E+SA+ELI+C+SY   +L+ ++L    K     +P  ++   ++ SA +  +++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF E  +IVPDK     + Q +  +   +++   K  ++K  YAGGLVLEPK G Y+ FILL+DFNSLYPSII EYNICFTT+ R    S    DQ    + +L H  +    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDG+ + +LLL KKKYA+L V       GK + KQELKGLDIVRRDWC+L+ E G  +++ IL ++  P D +  +I   L  I +++ N  + + ++ I KALT++P++Y + +  PHV VA+ INS GG  ++ +A DT+ Y+IC DG++ +A+QRAY+P+++      ++  LSID  YYL+ Q+HPVV R+ EPID ID++ +A  LGLDPS++    H  Q  E D          +  ++ DC+    +C KC  +   D       +++E P L      E   S  D  + V  KL   I R I  YYS    C+           C    R++ ++  +    C  C    ++       L  QL +YRF+      L     +++ E L +     V++VL +S Y  V+   L    S
Sbjct:  190 VEFDDGDFDEPMEEDNLESPSVVSSTIKKEEPKIKCVKEDSVKMEESSFMYVESMTTEVQVDSSRLPLVTGADGSQVFKFYWLDAYEDQYSQPGVVYLFGKVWIETAEAYVSCCVSVKNIERTVYLLPRENRVQLSTGKDTGVPVSMMNVYQEFNESVAEKYKIMKFKSKKVEKDYAFEIPDVPASSEYLEVRYSADSPQLPQDLKGETFSHVFGTNTSSLELFLLSRKIKGPSWLEIKSPQLSSQPMSWCKVEAVVMRPDQVNVVKDLAPPPVVVLSLSMKTVQNAKTHQNEIVAMAALVHHKFPFDKAPPQPPFQTHFCVLSKPNDCIFPYDFKEAVKRK-NAN----IEIALTERTLLGFFLAKIHKIDPDIIVGHDIYGFDLEVLLQRISSCKVPFWSKIGRLRRSV-MPKLGGRSG--FAERNAACGRIICDTEISAKELIRCKSYHLSELVHQIL----KTERVLMPPENIRNAYSDSAHLLYMLENTWTDAKFILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFTENNFIVPDKPVFKKIQQTTDDDNMDTDQNKNKKGRKKAAYAGGLVLEPKVGFYDKFILLLDFNSLYPSIIQEYNICFTTVQREAPTSQKGEDQEE--IPELPHSDLEM--GILPREIRKLVERRRHVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTHQGREILLHTKEMVQ--------KMN----LEVIYGDTDSIMINTNCNNL---EEVFKLGNRVKSEVNKSYKLLEIDIDGIFKSLLLLKKKKYAALTV--EPTGDGKYVTKQELKGLDIVRRDWCELAKEAGNYVISQILSDQ--PRDNIVENIQKKLTEIGENVTNGTVPISQYEINKALTKDPQDYPDKKSLPHVHVAMWINSQGG--RKVKAGDTISYVICQDGSNLSASQRAYAPEQL-----QKQENLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHHQQDEENDALLGGPSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIE-PGLKRCSKPECDASPLDYVIQVQNKLLLDIRRYIKKYYSGWLVCE--------EKTCQNRTRRVPLSFSRNGPICQACTKATLRSEYPEKALYTQLCFYRFIFDWDYALEKVKHFQESENLYKKLKSTVDQVLSQSGYSEVNLSKLFQTLS 1369

[Close]

BLAST of DNA polymerase vs. Ensembl Xenopus
Match: POLA1 (polymerase (DNA directed), alpha 1, catalytic subunit [Source:NCBI gene;Acc:100379926])

HSP 1 Score: 792.341 bits (2045), Expect = 0.000e+0
Identity = 486/1254 (38.76%), Postives = 711/1254 (56.70%), Query Frame = 2

Query:  755 IVLDDIDFDEPFETNPVVSAGFATDT----------------KLEEHKPLWETEEIEDESSNDKYDPFEN------IDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ----------AQMTEVYSEV-KSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAA--ALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPED-LAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY---HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSID-----FKMELEKPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFLLTG---------------KENLSYKQKELLQMCSKYVERVLERSDYMNVDFKSLMAKFS 4291
            +  DD DFDEP E + + S    + T                K+EE    + T    +ES  D+ D  E+      +D S L L+           YW DAY D+   PGVV+LFGK   E+ + +V+ C+ V  +ER +Y+LP++             M  VY E  +S+  K+ I   ++K V K YAF+  DVP  ++YL V+Y +  P+LP DL G+TFS +FG NTS LE+F+L  ++KGP WL     + SS   S CK+   +     + + K+ +PP   +LSL++KTV N K++ NEIVA+   +H++   D+APP   FQ +F +L+ P D + PYD  + +  +  AN    + I   ER+L+   L K+H +DPDIIVGH + G+ L +LLQR  +  +  W K GRL+RS+ +PK+ G S   + ER A  GR++CD E+SA+ELI+C+SY   +L+ ++L    K     +P  ++   ++ SA +  +++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF E  +IVPDK     + Q +  +   +++   K  ++K  YAGGLVLEPK G Y+ FILL+DFNSLYPSII EYNICFTT+ R    S    DQ    + +L H  +    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDG+ + +LLL KKKYA+L V       GK + KQELKGLDIVRRDWC+L+ E G  +++ IL ++  P D +  +I   L  I +++ N  + + ++ I KALT++P++Y + +  PHV VA+ INS GG  ++ +A DT+ Y+IC DG++ +A+QRAY+P+++      ++  LSID  YYL+ Q+HPVV R+ EPID ID++ +A  LGLDPS++    H  Q  E D          +  ++ DC+    +C KC  +   D       +++E P L      E   S  D  + V  KL   I R I  YYS    C+           C    R++ ++  +    C  C    ++       L  QL +YRF+                  K   + ++K  L      V++VL +S Y  V+   L    S
Sbjct:  196 VEFDDGDFDEPMEEDNLESPSVVSSTIKKEEPKIKCVKEDSVKMEESS--FMTSAALNESCWDQIDEVESMTTEVQVDSSRLPLVTGADGSQVFKFYWLDAYEDQYSQPGVVYLFGKVWIETAEAYVSCCVSVKNIERTVYLLPRENLSTGKDTGVPVSMMNVYQEFNESVAEKYKIMKFKSKVVEKDYAFEIPDVPASSEYLEVRYSADSPQLPQDLKGETFSHVFGTNTSSLELFLLSRKIKGPSWLEIKSPQLSSQPMSWCKVEAVVMRPDQVNVVKDLAPPPVVVLSLSMKTVQNAKTHQNEIVAMAALVHHKFPFDKAPPQPPFQTHFCVLSKPNDCIFPYDFKEAVKRK-NAN----IEIALTERTLLGFFLAKIHKIDPDIIVGHDIYGFDLEVLLQRISSCKVPFWSKIGRLRRSV-MPKLGGRSG--FAERNAACGRIICDTEISAKELIRCKSYHLSELVHQIL----KTERVLMPPENIRNAYSDSAHLLYMLENTWTDAKFILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFTENNFIVPDKPVFKKIQQTTDDDNMDTDQNKNKKGRKKAAYAGGLVLEPKVGFYDKFILLLDFNSLYPSIIQEYNICFTTVQREAPTSQKGEDQEE--IPELPHSDLEM--GILPREIRKLVERRRHVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTHQGREILLHTKEMVQ--------KMN----LEVIYGDTDSIMINTNCNNL---EEVFKLGNRVKSEVNKSYKLLEIDIDGIFKSLLLLKKKKYAALTV--EPTGDGKYVTKQELKGLDIVRRDWCELAKEAGNYVISQILSDQ--PRDNIVENIQKKLTEIGENVTNGTVPISQYEINKALTKDPQDYPDKKSLPHVHVAMWINSQGG--RKVKAGDTISYVICQDGSNLSASQRAYAPEQL-----QKQENLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHHQQDEENDALLGGPSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIE-PGLKRCSKPECDASPLDYVIQVQNKLLLDIRRYIKKYYSGWLVCE--------EKTCQNRTRRVPLSFSRNGPICQACTKATLRSEYPEKALYTQLCFYRFIFDWDYALEKVVSEQEREKKHFFTKRKKIFLFKLKSTVDQVLSQSGYSEVNLSKLFQTLS 1396

HSP 2 Score: 51.9878 bits (123), Expect = 9.016e-6
Identity = 38/126 (30.16%), Postives = 68/126 (53.97%), Query Frame = 2

Query:   14 IY*FEMSEDDTYGRPR-RQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQ--LDNFIEGDSEYMESGKEIFDESDEED--------IKIGPKRKKSMKNANLKNP 355
            ++  +MSE  ++   R R+  ++K  + + L +LK+AK  G  +K E+E +  IY+ V+EE Y K+   RQ       +  + Y+E G+EIFD+  E++         K  PK K ++K +++  P
Sbjct:   17 VFTLDMSESGSFAASRSRREKTEKSGRKEALERLKRAKA-GEKVKYEVEEISSIYEEVDEEQYSKIVRDRQDDDWIVDDDGTGYVEDGREIFDDDLEDNALADSGKRAKGAPKDKSNVKKSSVSKP 141

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Query:  755 IVLDDIDFDEPFETNPVVSAGFATDT----------------KLEEHKPLWETEEIEDESSNDKYDPFEN------IDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ----------AQMTEVYSEV-KSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAA--ALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPED-LAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY---HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSID-----FKMELEKPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFLLTG---------------KENLSYKQKELLQMCSKYVERVLERSDYMNVDFKSLMAKFS 4291
            +  DD DFDEP E + + S    + T                K+EE    + T    +ES  D+ D  E+      +D S L L+           YW DAY D+   PGVV+LFGK   E+ + +V+ C+ V  +ER +Y+LP++             M  VY E  +S+  K+ I   ++K V K YAF+  DVP  ++YL V+Y +  P+LP DL G+TFS +FG NTS LE+F+L  ++KGP WL     + SS   S CK+   +     + + K+ +PP   +LSL++KTV N K++ NEIVA+   +H++   D+APP   FQ +F +L+ P D + PYD  + +  +  AN    + I   ER+L+   L K+H +DPDIIVGH + G+ L +LLQR  +  +  W K GRL+RS+ +PK+ G S   + ER A  GR++CD E+SA+ELI+C+SY   +L+ ++L    K     +P  ++   ++ SA +  +++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF E  +IVPDK     + Q +  +   +++   K  ++K  YAGGLVLEPK G Y+ FILL+DFNSLYPSII EYNICFTT+ R    S    DQ    + +L H  +    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDG+ + +LLL KKKYA+L V       GK + KQELKGLDIVRRDWC+L+ E G  +++ IL ++  P D +  +I   L  I +++ N  + + ++ I KALT++P++Y + +  PHV VA+ INS GG  ++ +A DT+ Y+IC DG++ +A+QRAY+P+++      ++  LSID  YYL+ Q+HPVV R+ EPID ID++ +A  LGLDPS++    H  Q  E D          +  ++ DC+    +C KC  +   D       +++E P L      E   S  D  + V  KL   I R I  YYS    C+           C    R++ ++  +    C  C    ++       L  QL +YRF+                  K   + ++K  L      V++VL +S Y  V+   L    S
Sbjct:  184 VEFDDGDFDEPMEEDNLESPSVVSSTIKKEEPKIKCVKEDSVKMEESS--FMTSAALNESCWDQIDEVESMTTEVQVDSSRLPLVTGADGSQVFKFYWLDAYEDQYSQPGVVYLFGKVWIETAEAYVSCCVSVKNIERTVYLLPRENLSTGKDTGVPVSMMNVYQEFNESVAEKYKIMKFKSKVVEKDYAFEIPDVPASSEYLEVRYSADSPQLPQDLKGETFSHVFGTNTSSLELFLLSRKIKGPSWLEIKSPQLSSQPMSWCKVEAVVMRPDQVNVVKDLAPPPVVVLSLSMKTVQNAKTHQNEIVAMAALVHHKFPFDKAPPQPPFQTHFCVLSKPNDCIFPYDFKEAVKRK-NAN----IEIALTERTLLGFFLAKIHKIDPDIIVGHDIYGFDLEVLLQRISSCKVPFWSKIGRLRRSV-MPKLGGRSG--FAERNAACGRIICDTEISAKELIRCKSYHLSELVHQIL----KTERVLMPPENIRNAYSDSAHLLYMLENTWTDAKFILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFTENNFIVPDKPVFKKIQQTTDDDNMDTDQNKNKKGRKKAAYAGGLVLEPKVGFYDKFILLLDFNSLYPSIIQEYNICFTTVQREAPTSQKGEDQEE--IPELPHSDLEM--GILPREIRKLVERRRHVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTHQGREILLHTKEMVQ--------KMN----LEVIYGDTDSIMINTNCNNL---EEVFKLGNRVKSEVNKSYKLLEIDIDGIFKSLLLLKKKKYAALTV--EPTGDGKYVTKQELKGLDIVRRDWCELAKEAGNYVISQILSDQ--PRDNIVENIQKKLTEIGENVTNGTVPISQYEINKALTKDPQDYPDKKSLPHVHVAMWINSQGG--RKVKAGDTISYVICQDGSNLSASQRAYAPEQL-----QKQENLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHHQQDEENDALLGGPSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIE-PGLKRCSKPECDASPLDYVIQVQNKLLLDIRRYIKKYYSGWLVCE--------EKTCQNRTRRVPLSFSRNGPICQACTKATLRSEYPEKALYTQLCFYRFIFDWDYALEKVVSEQEREKKHFFTKRKKIFLFKLKSTVDQVLSQSGYSEVNLSKLFQTLS 1384

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BLAST of DNA polymerase vs. Ensembl Mouse
Match: Pola1 (polymerase (DNA directed), alpha 1 [Source:MGI Symbol;Acc:MGI:99660])

HSP 1 Score: 791.956 bits (2044), Expect = 0.000e+0
Identity = 551/1514 (36.39%), Postives = 809/1514 (53.43%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEGDSE--YMESGKEIFDESDE----------EDIKIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFK------FDIHQPKVISSSKIKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVVSAGFATDTKLEEHKPLWETEEIEDE--------------------SSNDKYDPFE-NIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ-------------AQMTEVYSEVKS-ILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQL-----EIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP------GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY--HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELE----KPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLLTGK---ENLSYKQKELL-------------QMCSKYVERVLERSDYMNVDFKSLMAKFS 4291
            R RR++ SKK  + + L +LKKAK  G   K E+E +  +Y+ V+EE Y KL + RQ D++I  D    Y+E G+EIFD+  E           D K   K +K +K  ++  P      F  I S  +K+    +  S          +L+   A+++ P       P L  KK+         F +H PK I S K  P  P  +  + +  PI   + ++               +   E PE  +    +  +D DFDE  +T  V        T  +E +P+   E   D                       +D+  P E  +D S+L L+           YW DAY D    PGVVFLFGK   ES K  V+ C+ V  +ER +Y LP++                M +VY E  S I AK+ I   ++K V K YAF+  DVP++++YL V+Y ++ P+LP +L G+TFS +FG NTS LE+F+++ ++KGPCWL     +  +   S CK          + + K+ SPP   ++S ++KT+ N +++ +EI+A+   +H+   LD+APP   FQ +F +++ PKD + P D  + ++ +   N K  V I A ER+LI   L K+H +DPDI+VGH +  ++L +LLQR     +  W K GRL+RS  +PK+   S + + ER AT GR++CDVE+SA+ELI C+SY   +L+Q++L  K +  V  +P  ++  +++ S+ +  L++    ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNE+LLLHAF E  YIVPDK        +L     EID    +  K  ++K TYAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT+ R        T +      D   + + + P      GILP EIRKLVE R  VKQL+   +L+ + +LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT+ GREIL++TK +++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++ID V + +LLL KKKYA+L  V    S G  I KQELKGLDIVRRDWC L+ + G  ++  IL ++ S + +  +I   L  I +++ N  + + +F I KALT++P++Y + +  PHV VAL INS GG  ++ +A DTV Y+IC DG++ TATQRAY+P+++          L+ID  YYLA Q+HPVV R+ EPID IDA  +A  LGLD +++  H  ++  E D          +  ++ DC+     C  C  +   D   E      +P L    NV+   S     V ++ KL   I R I  YY     C+    C  +  +       L  +     CP C   +++P  S   L  QL +YR++       E L+  +K+ L             +      E+ L  S Y  V+   L A ++
Sbjct:   26 RARREKKSKK-GRQEALERLKKAKA-GEKYKYEVEDLTSVYEEVDEEQYSKLVQARQDDDWIVDDDGIGYVEDGREIFDDDLEDDALDTCGKGSDGKAHRKDRKDVKKPSVTKPNNIKAMF--IASAGKKTTDKAVDLSKDDLLGDILQDLNTETAQITPP-------PVLIPKKKRSTGALLNPFSVHTPKAIPSGK--PASPV-LRNEPLLTPIPLKRAELA------------GELAQPECPEDEQELGVMEFEDGDFDESMDTEKVDEKPVTAKTWDQETEPVERVEHEADPERGTTSYLENFLPDVSCWDIDQDDESIPQEVQVDSSNLPLVKGADDEQVFQFYWLDAYEDPYNQPGVVFLFGKVWIESVKTHVSCCVMVKNIERTLYFLPREMKFDLNTGKETAIPVTMKDVYEEFDSKISAKYKIMKFKSKIVEKNYAFEIPDVPEKSEYLEVRYSAEVPQLPQNLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKNPQLLNQPISWCKFEVMALKPDLVNVIKDVSPPPLVVMSFSMKTMQNVQNHQHEIIAMAALVHHSFALDKAPPEPPFQTHFCVVSKPKDCIFPCDFKEVISKK---NMK--VEIAATERTLIGFFLAKVHKIDPDILVGHNICSFELEVLLQRINECKVPYWSKIGRLRRS-NMPKLG--SRSGFGERNATCGRMICDVEISAKELIHCKSYHLSELVQQIL--KTERIV--IPTENIRNMYSESSYLLYLLEHIWKDARFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKK-GRKKATYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRV-------TSEVQKATEDEEQEQIPELPDPNLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLVLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKDMVQ--------KMN----LEVIYGDTDSIMINTNSTNL---EEVFKLGNKVKSEVNKLYKLLEIDIDAVFKSLLLLKKKKYAAL--VVEPTSDGNYITKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQ-SRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDRKSLPHVHVALWINSQGG--RKVKAGDTVSYVICQDGSNLTATQRAYAPEQLQKLDN-----LAIDTQYYLAQQIHPVVARICEPIDGIDAVLIALWLGLDSTQFRVHQYHKDEENDALLGGPAQLTDEEKYKDCEKFKCLCPSCGTENIYDNVFEGSGLDMEPSLYRCSNVDCKVSPLTFMVQLSNKLIMDIRRCIKKYYDGWLICEEPTCCSRLRRL------PLHFSRNGPLCPVCMKAVLRPEYSDKSLYTQLCFYRYIFDADCALEKLTEHEKDKLKKQFFPLRVLQDYRKVKNIAEQFLSWSGYSEVNLSKLFANYA 1462

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BLAST of DNA polymerase vs. Ensembl Mouse
Match: Pold1 (polymerase (DNA directed), delta 1, catalytic subunit [Source:MGI Symbol;Acc:MGI:97741])

HSP 1 Score: 176.792 bits (447), Expect = 3.271e-44
Identity = 181/657 (27.55%), Postives = 306/657 (46.58%), Query Frame = 2

Query: 1721 NERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGR-------LKRSIALPKITGHSNTSWIERMATAGRLLCDV-EVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDR---CKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVK-QLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKG-IQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAG-GSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
             E  L+    + +  +DPD+I G+ +  + L  L+ R QAL ++ +   GR       ++ S    +  G  ++  I   +  GR+  D+ +V  RE  K RSY    +    L E+ +    S+ + DL     +    ++L    L ++ + + L+  L VL   +E+  + G  +   L+ G+  +    LL     +  ++P           ++ + S +           Y G  V+EP KG Y+  I  +DF+SLYPSI++ +N+C+TT+ R    + L +   +       D   KS  +  G+LP  +  L+ AR   K +L    +  + ++L  D RQ ALK++ANS+YG  G    +    +++  VT  GR+++  TK+++E   +K + +   +    ++YGDTDSVM   G+ +V +    M +G+     V+  +   I+L  + V    LL++KK+YA L   SR  +  K+    + KGL+ VRRD C L       ++T  L   L   D   ++ +    ISD + N +I + + +ITK LTR   +Y+  Q   HV++A R+     GS       D V Y+I        A  ++  P  VL      E  L ID  YYL  QL   + R+ EPI
Sbjct:  371 REEDLLQAWADFILAMDPDVITGYNIQNFDLPYLISRAQALKVDRFPFLGRVTGLRSNIRDSSFQSRQVGRRDSKVI---SMVGRVQMDMLQVLLREH-KLRSYTLNAVSFHFLGEQKEDVQHSI-ITDLQN--GNEQTRRRLAVYCLKDAFLPLRLLERLMVLVNNVEMARVTGVPLGYLLTRGQQVKVVSQLLRQAMRQGLLMP----------VVKTEGSED-----------YTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGAAQKLGLKPDEFIKTPTGDEFVKSSVR-KGLLPQILENLLSARKRAKAELAQETDPLRRQVL--DGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVE---SKYTVENGYDANAKVVYGDTDSVMCRFGVSSVAE---AMSLGREAANWVSSHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRSDAHDKM----DCKGLEAVRRDNCPLVAN----LVTSSLRRILVDRDPDGAVAHAKDVISDLLCN-RIDISQLVITKELTRAAADYAGKQA--HVELAERMRKRDPGSAPSL--GDRVPYVIIGAAKGVAAYMKSEDPLFVL------EHSLPIDTQYYLEQQLAKPLLRIFEPI 971

[Close]

BLAST of DNA polymerase vs. Ensembl Mouse
Match: Pold1 (polymerase (DNA directed), delta 1, catalytic subunit [Source:MGI Symbol;Acc:MGI:97741])

HSP 1 Score: 155.606 bits (392), Expect = 8.981e-38
Identity = 158/582 (27.15%), Postives = 277/582 (47.59%), Query Frame = 2

Query: 1721 NERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGR-------LKRSIALPKITGHSNTSWIERMATAGRLLCDV-EVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDR---CKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVK-QLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKG-IQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALR 3427
             E  L+    + +  +DPD+I G+ +  + L  L+ R QAL ++ +   GR       ++ S    +  G  ++  I   +  GR+  D+ +V  RE  K RSY    +    L E+ +    S+ + DL     +    ++L    L ++ + + L+  L VL   +E+  + G  +   L+ G+  +    LL     +  ++P           ++ + S +           Y G  V+EP KG Y+  I  +DF+SLYPSI++ +N+C+TT+ R    + L +   +       D   KS  +  G+LP  +  L+ AR   K +L    +  + ++L  D RQ ALK++ANS+YG  G    +    +++  VT  GR+++  TK+++E   +K + +   +    ++YGDTDSVM   G+ +V +    M +G+     V+  +   I+L  + V    LL++KK+YA L   SR  +  K+    + KGL+ VRRD C L       ++T  L   L   D   ++ +    ISD + N +I + + +ITK LTR   +Y+  Q   HV++A R
Sbjct:  371 REEDLLQAWADFILAMDPDVITGYNIQNFDLPYLISRAQALKVDRFPFLGRVTGLRSNIRDSSFQSRQVGRRDSKVI---SMVGRVQMDMLQVLLREH-KLRSYTLNAVSFHFLGEQKEDVQHSI-ITDLQN--GNEQTRRRLAVYCLKDAFLPLRLLERLMVLVNNVEMARVTGVPLGYLLTRGQQVKVVSQLLRQAMRQGLLMP----------VVKTEGSED-----------YTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGAAQKLGLKPDEFIKTPTGDEFVKSSVR-KGLLPQILENLLSARKRAKAELAQETDPLRRQVL--DGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVE---SKYTVENGYDANAKVVYGDTDSVMCRFGVSSVAE---AMSLGREAANWVSSHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRSDAHDKM----DCKGLEAVRRDNCPLVAN----LVTSSLRRILVDRDPDGAVAHAKDVISDLLCN-RIDISQLVITKELTRAAADYAGKQA--HVELAER 904

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BLAST of DNA polymerase vs. Ensembl Mouse
Match: Rev3l (REV3 like, DNA directed polymerase zeta catalytic subunit [Source:MGI Symbol;Acc:MGI:1337131])

HSP 1 Score: 124.79 bits (312), Expect = 6.714e-28
Identity = 150/673 (22.29%), Postives = 272/673 (40.42%), Query Frame = 2

Query: 1706 VLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMAT---AGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIK--QLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTT-------IDRCKYLSVGDTDQAM--HILMDLSHKSVAKP-----------PGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYG--CLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVN-RRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLI 3640
            V   A+E++L   + N +   DPDI++G+ +  +  G LLQR  AL+++      R+       +     +    + M+     GR+  ++    R  +   +Y   ++   +L ++F  F   V    L   F++   +   +++D  +     N+ ++ +L ++    E+  + G      L+ G   R E ++L       YI      ++ Q SQ+   Q                  L++EP+   Y N +L++DF SLYPSI++ YN CF+T       + +      G T   +   +L  + H     P            G+LP  + ++++ R  VKQ + +    +      + RQ  LK+ AN  +G     FS  R    ++   +    RE L    K++ D                ++YGDTDS+ V        Q     KIGQ I E V     + ++L  + V    +L  KK+Y      + D+         + KG++ VRRD C    ++ +R L ++ E      D++  I  Y++     +   K S+  FI  K   R   +Y      P +++  ++  A     + R  + V Y+I          Q    P EVL     ++  L ++  YY+  Q+ P + R+ 
Sbjct: 2368 VTYAADEKALFQEITNIIKRYDPDILLGYEIQMHSWGYLLQRAAALSVDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRV----LSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYI--PVTPSIQQRSQMRAPQ---------------CVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQIRHDVTVSPNGVAFVKPSVRKGVLPRMLEEILKTRLMVKQSMKSYKQDRALSRMLNARQLGLKLIANVTFGYTAANFS-GRMPCIEVGDSIVHKARETLERAIKLVND---------TKKWGARVVYGDTDSMFVLLKGATKEQ---SFKIGQEIAEAVTATNPRPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKEPVF----DAKGIETVRRDSCPAVSKILERSLKLLFET----RDISL-IKQYVQRQCMKLVEGKASIQDFIFAKEY-RGSFSYRPGACVPALELTRKM-LAYDRRSEPRVGERVPYVIIYGTPGLPLIQLIRRPAEVL-----QDPTLRLNATYYITKQILPPLARIF 2990

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Query: 1706 VLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMAT---AGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIK--QLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTT-------IDRCKYLSVGDTDQAM--HILMDLSHKSVAKP-----------PGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYG--CLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVN-RRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLI 3640
            V   A+E++L   + N +   DPDI++G+ +  +  G LLQR  AL+++      R+       +     +    + M+     GR+  ++    R  +   +Y   ++   +L ++F  F   V    L   F++   +   +++D  +     N+ ++ +L ++    E+  + G      L+ G   R E ++L       YI      ++ Q SQ+   Q                  L++EP+   Y N +L++DF SLYPSI++ YN CF+T       + +      G T   +   +L  + H     P            G+LP  + ++++ R  VKQ + +    +      + RQ  LK+ AN  +G     FS  R    ++   +    RE L    K++ D                ++YGDTDS+ V        Q     KIGQ I E V     + ++L  + V    +L  KK+Y      + D+         + KG++ VRRD C    ++ +R L ++ E      D++  I  Y++     +   K S+  FI  K   R   +Y      P +++  ++  A     + R  + V Y+I          Q    P EVL     ++  L ++  YY+  Q+ P + R+ 
Sbjct: 2368 VTYAADEKALFQEITNIIKRYDPDILLGYEIQMHSWGYLLQRAAALSVDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRV----LSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYI--PVTPSIQQRSQMRAPQ---------------CVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQIRHDVTVSPNGVAFVKPSVRKGVLPRMLEEILKTRLMVKQSMKSYKQDRALSRMLNARQLGLKLIANVTFGYTAANFS-GRMPCIEVGDSIVHKARETLERAIKLVND---------TKKWGARVVYGDTDSMFVLLKGATKEQ---SFKIGQEIAEAVTATNPRPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKEPVF----DAKGIETVRRDSCPAVSKILERSLKLLFET----RDISL-IKQYVQRQCMKLVEGKASIQDFIFAKEY-RGSFSYRPGACVPALELTRKM-LAYDRRSEPRVGERVPYVIIYGTPGLPLIQLIRRPAEVL-----QDPTLRLNATYYITKQILPPLARIF 2990

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BLAST of DNA polymerase vs. UniProt/SwissProt
Match: sp|Q9DE46|DPOLA_XENLA (DNA polymerase alpha catalytic subunit OS=Xenopus laevis OX=8355 GN=pola1 PE=1 SV=1)

HSP 1 Score: 824.313 bits (2128), Expect = 0.000e+0
Identity = 558/1522 (36.66%), Postives = 825/1522 (54.20%), Query Frame = 2

Query:   29 MSEDDTYGRPR-RQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEG--DSEYMESGKEIFDESDEEDI--------KIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEE--------FKFDIHQPKVISSSK------IKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDC--IVLDDIDFDEPFETN----PVVSAGFATDTK---------LEEHKPLWETEEIEDESSNDKYDPFE------NIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ-------------AQMTEVYSEVKSILA-KHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALP-QNSQLEI--DQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPED-LAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY---HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSID-----FKMELEKPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL---------LTGKENLSYKQKELLQ-------MCSKYVERVLERSDYMNVDFKSLM 4279
            MS+  ++   R R+  ++K  + + L +LK+AK  G  +K E+E V  IY+ V+E  Y KL   RQ D++I     + Y+E G+EIFD+  E++         K  PK K ++K +++  P      F  + S  +K+    +  S          +L      ++ P       P ++ KK++        F      PKV+ +S        KP  P    + +V   IK   K  + +         P  +E      Q K ED   +  DD DFDEP E +    PV S+   T  +         ++E K  + T    +ES  D+ D  E       +D S L L+           YW DAY D+   PGVV+LFGK   ES   +V+ C+ V  +ER +Y+LP++                M  VY E    +A K+ I   ++K V K YAF+  DVP  ++YL V+Y +  P+LP DL G+TFS +FG NTS LE+F+L  ++KGP WL     + SS   S CK+   +     + + K+ +PP   +LSL++KTV N K++ NEIVAI   +H+   LD+APP   FQ +F +L+   D + PYD N+ +  +  AN    + I   ER+L+   L K+H +DPD+IVGH + G+ L +LLQR  +  +  W K GRL+RS+ +PK+ G S   + ER A  GR++CD+E+SA+ELI+C+SY   +L+ ++L    KA    +P  ++   +N S  +  +++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF E  +IVPDK      Q + +E   D   +Q    S++K  YAGGLVLEPK G Y+ FILL+DFNSLYPSII EYNICFTT+ R    +    DQ    + +L H  +    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K E+N+ YK ++++IDG+ + +LLL KKKYA+L V       GK + KQELKGLDIVRRDWC+L+ + G  +++ IL ++  P D +  +I   L  I +++ N  + + ++ I KALT++P++Y + +  PHV VAL INS GG  ++ +A DT+ Y+IC DG++ +A+QRAY+ +++      ++  LSID  YYL+ Q+HPVV R+ EPID ID++ +A  LGLDPS++    H  Q  E D          +  ++ DC+    +C KC  +   D       +++E P L      E   S  D  + V+ KL   I R I  YYS    C+           C    R+L ++  +    C  C    ++       L  QL +YRF+         +  ++   + +K+L Q            V++VL RS Y  V+   L 
Sbjct:    1 MSDSGSFAASRSRREKTEKSGRKEALERLKRAKA-GEKVKYEVEQVSSIYEEVDEAEYSKLVRDRQDDDWIVDDDGTGYVEDGREIFDDDLEDNALADSGKGAKGAPKDKTNVKKSSVSKPNNIKSMF--MASAVKKTTDKAVDLSKDDLLGDLLQDLKSQAVPITPP-------PVITLKKKKLAGSPLNPFSVPPTAPKVLPTSVKRLPAVTKPGHPAAQSKASVPRQIKKEPKAELISSAVG-----PLKVE-----AQVKEEDSGMVEFDDGDFDEPMEEDVEITPVDSSTIKTQAQSIKCVKEENIKEEKSSFITSATLNESCWDQIDEAEPMTTEIQVDSSHLPLVTGADGSQVFRFYWLDAYEDQYSQPGVVYLFGKVWIESADAYVSCCVSVKNIERTVYLLPRENRVQLSTGKDTGAPVSMMHVYQEFNEAVAEKYKIMKFKSKKVDKDYAFEIPDVPASSEYLEVRYSADSPQLPQDLKGETFSHVFGTNTSSLELFLLSRKIKGPSWLEIKSPQLSSQPMSWCKVEAVVTRPDQVSVVKDLAPPPVVVLSLSMKTVQNAKTHQNEIVAIAALVHHTFPLDKAPPQPPFQTHFCVLSKLNDCIFPYDYNEAVKQK-NAN----IEIALTERTLLGFFLAKIHKIDPDVIVGHDIYGFDLEVLLQRINSCKVPFWSKIGRLRRSV-MPKLGGRSG--FAERNAACGRIICDIEISAKELIRCKSYHLSELVHQIL----KAERVVIPPENIRNAYNDSVHLLYMLENTWIDAKFILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFTENNFIVPDKPVFKKMQQTTVEDNDDMGTDQNKNKSRKKAAYAGGLVLEPKVGFYDKFILLLDFNSLYPSIIQEYNICFTTVHREAPSTQKGEDQDE--IPELPHSDLEM--GILPREIRKLVERRRHVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTHQGREILLHTKEMVQ--------KMN----LEVIYGDTDSIMINTNCNNL---EEVFKLGNRVKSEINKSYKLLEIDIDGIFKSLLLLKKKKYAALTV--EPTGDGKYVTKQELKGLDIVRRDWCELAKQAGNYVISQILSDQ--PRDSIVENIQKKLTEIGENVTNGTVPITQYEINKALTKDPQDYPDKKSLPHVHVALWINSQGG--RKVKAGDTISYVICQDGSNLSASQRAYAQEQL-----QKQENLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHYQQDEENDALLGGPSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIE-PGLKRCSKPECDASPLDYVIQVHNKLLLDIRRYIKKYYSGWLVCE--------EKTCQNRTRRLPLSFSRNGPICQACSKATLRSEYPEKALYTQLCFYRFIFDWDYALEKVVSEQERGHLKKKLFQESENQYKKLKSTVDQVLSRSGYSEVNLSKLF 1451

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BLAST of DNA polymerase vs. UniProt/SwissProt
Match: sp|P09884|DPOLA_HUMAN (DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2)

HSP 1 Score: 803.127 bits (2073), Expect = 0.000e+0
Identity = 559/1515 (36.90%), Postives = 822/1515 (54.26%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEGDSE--YMESGKEIFDESDEEDIKIGPKRKKSMK--NANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNRE--EIKAP--FLSKKKEEF-----KFDIHQPKVISSSKIKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVVSAGFATDTKLEEHKPLWETEEIEDESSNDK---------------YDPFE-----------NIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQA-------------QMTEVYSEV-KSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQL-----EIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP------GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY--HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELE----KPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMT---TGQFACPRCESGIMKPLLSSSLLNRQLGYYRF----------LLTGKENLSYKQK----ELLQMCSKY---VERVLERSDYMNVDFKSLMA 4282
            R RR++ SKK  + + L +LKKAK  G   K E+E    +Y+ V+EE Y KL + RQ D++I  D    Y+E G+EIFD+  E+D     ++ K  K  N + +N KK  +       ++ KS+F        + K ++ +    L   L   N E  +I  P   + KKK         F +H    + S KI     ++ P  T   P+   + +   +    E     ST E  E+         +  +D DFDEP E   V     A     +E +P    EE++ E+ + K               +D  +            +D S L L+           YW DAY D+   PGVVFLFGK   ES +  V+ C+ V  +ER +Y LP++                M +VY E  + I  K+ I   ++KPV K YAF+  DVP++++YL V+Y ++ P+LP DL G+TFS +FG NTS LE+F+++ ++KGPCWL     +  +   S CK+         + + K+ SPP   +++ ++KT+ N K++ NEI+A+   +H+   LD+A P   FQ++F +++ PKD + PY   + +  +   N K  V + A ER+L+   L K+H +DPDIIVGH + G++L +LLQR        W K GRLKRS  +PK+ G S   + ER AT GR++CDVE+SA+ELI+C+SY   +L+Q++L    K     +P+ ++  +++ S+ +  L++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNE+LLLHAF E  YIVPDK        +L     EID    +  K  ++K  YAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT+ R          +A  +  D   + + + P      GILP EIRKLVE R  VKQL+   +L+ + +LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT+ GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L  V    S G  + KQELKGLDIVRRDWC L+ + G  ++  IL ++ S + +  +I   L  I +++ N  + + +F I KALT++P++Y + +  PHV VAL INS GG  ++ +A DTV Y+IC DG++ TA+QRAY+P+++      ++  L+ID  YYLA Q+HPVV R+ EPID IDA  +A  LGLDP+++  HH ++  E D          +  ++ DC+     C  C  +   D   +      +P L    N++   S     V ++ KL   I R I  YY     C+           C    R L +    TG   CP C    ++P  S   L  QL +YR+          L T  E    K++    ++LQ   K     E+ L RS Y  V+   L A
Sbjct:   20 RARREKKSKK-GRQEALERLKKAKA-GEKYKYEVEDFTGVYEEVDEEQYSKLVQARQDDDWIVDDDGIGYVEDGREIFDDDLEDDALDADEKGKDGKARNKDKRNVKKLAV----TKPNNIKSMFIACAGKKTADKAVDLSKDGLLGDILQDLNTETPQITPPPVMILKKKRSIGASPNPFSVHTATAVPSGKIASPVSRKEPPLT---PVPLKRAEFAGDDVQVE-----STEEEQES-------GAMEFEDGDFDEPMEVEEVDLEPMAAKAWDKESEP---AEEVKQEADSGKGTVSYLGSFLPDVSCWDIDQEGDSSFSVQEVQVDSSHLPLVKGADEEQVFHFYWLDAYEDQYNQPGVVFLFGKVWIESAETHVSCCVMVKNIERTLYFLPREMKIDLNTGKETGTPISMKDVYEEFDEKIATKYKIMKFKSKPVEKNYAFEIPDVPEKSEYLEVKYSAEMPQLPQDLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKSPQLLNQPVSWCKVEAMALKPDLVNVIKDVSPPPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAAPKPPFQSHFCVVSKPKDCIFPYAFKEVIEKK---NVK--VEVAATERTLLGFFLAKVHKIDPDIIVGHNIYGFELEVLLQRINVCKAPHWSKIGRLKRS-NMPKLGGRSG--FGERNATCGRMICDVEISAKELIRCKSYHLSELVQQIL----KTERVVIPMENIQNMYSESSQLLYLLEHTWKDAKFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKK-GRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRV-------ASEAQKVTEDGEQEQIPELPDPSLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKEMVQ--------KMN----LEVIYGDTDSIMINTNSTNL---EEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAAL--VVEPTSDGNYVTKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQ-SRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKKSLPHVHVALWINSQGG--RKVKAGDTVSYVICQDGSNLTASQRAYAPEQL-----QKQDNLTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDPTQFRVHHYHKDEENDALLGGPAQLTDEEKYRDCERFKCPCPTCGTENIYDNVFDGSGTDMEPSLYRCSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICE--------EPTCRNRTRHLPLQFSRTGPL-CPACMKATLQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTPKVLQDYRKLKNTAEQFLSRSGYSEVNLSKLFA 1456

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BLAST of DNA polymerase vs. UniProt/SwissProt
Match: sp|P33609|DPOLA_MOUSE (DNA polymerase alpha catalytic subunit OS=Mus musculus OX=10090 GN=Pola1 PE=1 SV=2)

HSP 1 Score: 791.956 bits (2044), Expect = 0.000e+0
Identity = 551/1514 (36.39%), Postives = 809/1514 (53.43%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEGDSE--YMESGKEIFDESDE----------EDIKIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFK------FDIHQPKVISSSKIKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVVSAGFATDTKLEEHKPLWETEEIEDE--------------------SSNDKYDPFE-NIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ-------------AQMTEVYSEVKS-ILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQL-----EIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP------GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY--HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELE----KPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLLTGK---ENLSYKQKELL-------------QMCSKYVERVLERSDYMNVDFKSLMAKFS 4291
            R RR++ SKK  + + L +LKKAK  G   K E+E +  +Y+ V+EE Y KL + RQ D++I  D    Y+E G+EIFD+  E           D K   K +K +K  ++  P      F  I S  +K+    +  S          +L+   A+++ P       P L  KK+         F +H PK I S K  P  P  +  + +  PI   + ++               +   E PE  +    +  +D DFDE  +T  V        T  +E +P+   E   D                       +D+  P E  +D S+L L+           YW DAY D    PGVVFLFGK   ES K  V+ C+ V  +ER +Y LP++                M +VY E  S I AK+ I   ++K V K YAF+  DVP++++YL V+Y ++ P+LP +L G+TFS +FG NTS LE+F+++ ++KGPCWL     +  +   S CK          + + K+ SPP   ++S ++KT+ N +++ +EI+A+   +H+   LD+APP   FQ +F +++ PKD + P D  + ++ +   N K  V I A ER+LI   L K+H +DPDI+VGH +  ++L +LLQR     +  W K GRL+RS  +PK+   S + + ER AT GR++CDVE+SA+ELI C+SY   +L+Q++L  K +  V  +P  ++  +++ S+ +  L++    ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNE+LLLHAF E  YIVPDK        +L     EID    +  K  ++K TYAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT+ R        T +      D   + + + P      GILP EIRKLVE R  VKQL+   +L+ + +LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT+ GREIL++TK +++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++ID V + +LLL KKKYA+L  V    S G  I KQELKGLDIVRRDWC L+ + G  ++  IL ++ S + +  +I   L  I +++ N  + + +F I KALT++P++Y + +  PHV VAL INS GG  ++ +A DTV Y+IC DG++ TATQRAY+P+++          L+ID  YYLA Q+HPVV R+ EPID IDA  +A  LGLD +++  H  ++  E D          +  ++ DC+     C  C  +   D   E      +P L    NV+   S     V ++ KL   I R I  YY     C+    C  +  +       L  +     CP C   +++P  S   L  QL +YR++       E L+  +K+ L             +      E+ L  S Y  V+   L A ++
Sbjct:   26 RARREKKSKK-GRQEALERLKKAKA-GEKYKYEVEDLTSVYEEVDEEQYSKLVQARQDDDWIVDDDGIGYVEDGREIFDDDLEDDALDTCGKGSDGKAHRKDRKDVKKPSVTKPNNIKAMF--IASAGKKTTDKAVDLSKDDLLGDILQDLNTETAQITPP-------PVLIPKKKRSTGALLNPFSVHTPKAIPSGK--PASPV-LRNEPLLTPIPLKRAELA------------GELAQPECPEDEQELGVMEFEDGDFDESMDTEKVDEKPVTAKTWDQETEPVERVEHEADPERGTTSYLENFLPDVSCWDIDQDDESIPQEVQVDSSNLPLVKGADDEQVFQFYWLDAYEDPYNQPGVVFLFGKVWIESVKTHVSCCVMVKNIERTLYFLPREMKFDLNTGKETAIPVTMKDVYEEFDSKISAKYKIMKFKSKIVEKNYAFEIPDVPEKSEYLEVRYSAEVPQLPQNLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKNPQLLNQPISWCKFEVMALKPDLVNVIKDVSPPPLVVMSFSMKTMQNVQNHQHEIIAMAALVHHSFALDKAPPEPPFQTHFCVVSKPKDCIFPCDFKEVISKK---NMK--VEIAATERTLIGFFLAKVHKIDPDILVGHNICSFELEVLLQRINECKVPYWSKIGRLRRS-NMPKLG--SRSGFGERNATCGRMICDVEISAKELIHCKSYHLSELVQQIL--KTERIV--IPTENIRNMYSESSYLLYLLEHIWKDARFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKK-GRKKATYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRV-------TSEVQKATEDEEQEQIPELPDPNLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLVLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKDMVQ--------KMN----LEVIYGDTDSIMINTNSTNL---EEVFKLGNKVKSEVNKLYKLLEIDIDAVFKSLLLLKKKKYAAL--VVEPTSDGNYITKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQ-SRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDRKSLPHVHVALWINSQGG--RKVKAGDTVSYVICQDGSNLTATQRAYAPEQLQKLDN-----LAIDTQYYLAQQIHPVVARICEPIDGIDAVLIALWLGLDSTQFRVHQYHKDEENDALLGGPAQLTDEEKYKDCEKFKCLCPSCGTENIYDNVFEGSGLDMEPSLYRCSNVDCKVSPLTFMVQLSNKLIMDIRRCIKKYYDGWLICEEPTCCSRLRRL------PLHFSRNGPLCPVCMKAVLRPEYSDKSLYTQLCFYRYIFDADCALEKLTEHEKDKLKKQFFPLRVLQDYRKVKNIAEQFLSWSGYSEVNLSKLFANYA 1462

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BLAST of DNA polymerase vs. UniProt/SwissProt
Match: sp|O89042|DPOLA_RAT (DNA polymerase alpha catalytic subunit (Fragment) OS=Rattus norvegicus OX=10116 GN=Pola1 PE=1 SV=1)

HSP 1 Score: 783.482 bits (2022), Expect = 0.000e+0
Identity = 548/1493 (36.70%), Postives = 814/1493 (54.52%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEGDSE--YMESGKEIFDE----------SDEEDIKIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFK------FDIHQPKVISSSKI-KPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPV-----VSAGF-------------------ATDTKLEEHKPLWETEEIEDESSNDKYDPFENIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQA-------------QMTEVYSEVKS-ILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDK-----AAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDT-DQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY--HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSID--FK---MELEKPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFLLTGK---ENLSYKQKELLQMCSKYVERVLERSDYMNV 4261
            R RR++ SKK  + + L +LKKAK  G   K E+E +  +Y+ V+EE Y KL + RQ D++I  D    Y+E G+EIFD+           +  D K   K +K +K  ++  P      F  I S  +K+       +  +    +++ L D+L +L+T   +    P L  KK+         F +H    + S KI  P   KE P   V  P+K              + +    +   E PE  +    I  +D DFDEP +T  V     V+A                      T + L+   P     +I+ +  N        +D + L L+           YW DAY D    PGVVFLFGK   ES K  V+ C+ V  +ER +Y LP++                M +VY E  S I AK+ I   ++K V K YAF+  DVP++++YL V+Y ++ P+LP +L G+TFS +FG NTS LE+F+++ ++KGPCWL     +  +   S CK          + + K+ SPP   ++S ++KT+ N +++ +EI+A+   +H+   LD+APP   FQ +F +++ PKD + P    + +  +        V + A ER+L+   L K+H LDPDI+VGH + G++L +LLQR     +  W K GRL+RS  +PK+   S + + ER AT GR++CDVE+S +ELI C+SY   +L+Q++L  K +  V  +P  ++  +++  + +  L++    ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNE+LLLHAF E  YIVPDK         P +   EID    +  K  ++K  YAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT+ R    ++  T D+    + +L   ++    GILP EIRKLVE R  VKQL+   +L+ + +LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT+ GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L  V    S G  I KQELKGLDIVRRDWC L+ + G  ++  IL ++ S + +  +I   L  I +++ N  + + +F I KALT++P++Y + +  PHV VAL INS GG  ++ +A DTV Y+IC DG++  ATQRAY+P+++      ++  L+ID  YYLA Q+HPVV R+ EPID IDA  +A  LGLD +++  H  ++  E D          +  ++ DC+     C  C  +   D  F+   M++E P L    N++   S A   V ++ KL   I R I  YY     C+           C    R+L +   +    CP C   +++P  S   L  QL +YR++       E L   +K+ L+    +  RVL+  DY  V
Sbjct:   26 RARREKKSKK-GRQEALERLKKAKA-GEKYKYEVEDLTSVYEEVDEEQYSKLVQARQDDDWIVDDDGIGYVEDGREIFDDDLEDDALDTCGEGSDGKAHRKDRKDVKKPSVTKPNNIKAMF--IASAGKKT-------TDKTVDLSKDDLLGDILQDLNTETPQIAPPPVLIPKKKRSTGASPNPFSVHTATAVPSGKIASPVSRKEPPLTPV--PLK--------------RAEFAGDLAQPECPEDEQESGVIEFEDGDFDEPMDTEEVDEEEPVTAKIWDQESEPVEGVKHEADPETGTTSFLDSFLPDVSCWDIDQKDENSFLLQEVQVDSNHLPLVKGADDEQVFQFYWLDAYEDPYNQPGVVFLFGKVWVESAKTHVSCCVMVKNIERTLYFLPREMKIDLNTGKETATPITMKDVYEEFDSKISAKYKIMKFKSKIVEKNYAFEIPDVPEKSEYLEVRYSAEVPQLPQNLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKNPQLLNQPISWCKFEAMALKPDLVNVIKDVSPPPLVVMSFSMKTMQNVQNHQHEIIAMAALVHHNFPLDKAPPKPPFQTHFCVVSKPKDCIFPCAFKEVIKKK-----NMEVEVAATERTLLGFFLAKVHKLDPDILVGHNICGFELEVLLQRINECKVPFWSKIGRLRRS-NMPKLG--SRSGFGERNATCGRMICDVEISVKELIHCKSYHLSELVQQIL--KTERIV--IPTENIRNMYSEPSHLLYLLEHIWKDARFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKPGDEDEEIDGDTNKYKK-GRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVASETLKATEDEEQEQIPELPDPNLDM--GILPREIRKLVERRKQVKQLMKQQDLNPDLVLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKEMVQ--------KMN----LEVIYGDTDSIMINTNSTNL---EEVFKLGNKVKNEVNKLYKLLEIDIDGVFKSLLLLKKKKYAAL--VVEPTSDGNYITKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQ-SRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKKSLPHVHVALWINSQGG--RKVKAGDTVSYVICQDGSNLPATQRAYAPEQL-----QKQDNLAIDTQYYLAQQIHPVVARICEPIDGIDAVLIALWLGLDSTQFRVHQYHKDEENDALLGGPAQLTDEEKYKDCEKFKCLCPSCGTENIYDNVFEGSGMDME-PSLNRCSNIDCKASPATFMVQLSNKLIMDIRRCIKKYYDGWLICE--------EPTCRNRIRRLPLHFSRNGPLCPACMKAVLRPEYSDKSLYTQLCFYRYIFDADCALEKLPEHEKDKLKK-QFFTPRVLQ--DYRKV 1439

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BLAST of DNA polymerase vs. UniProt/SwissProt
Match: sp|P26019|DPOLA_DROME (DNA polymerase alpha catalytic subunit OS=Drosophila melanogaster OX=7227 GN=DNApol-alpha180 PE=1 SV=2)

HSP 1 Score: 676.781 bits (1745), Expect = 0.000e+0
Identity = 443/1177 (37.64%), Postives = 653/1177 (55.48%), Query Frame = 2

Query:  932 LKLIYWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLP-------------KDQAQMTEVYSEVKSILAKH-GIESLRTKPVTKKYAFQFI--DVPDETDYLMVQYDSK--FPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPPFSILSL-----NIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEAN-ERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQ--SNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQHNEADNTYSKQ-----ESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELEKPWLCGNCNVELLYSHADA----------VNVNKKLKEIIDRIIHIYYSCISTC---QCGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLLT-GKENLSYKQ------KELLQMCSKYVERVLERSDYMNVDFKSLMAKFSRQIKI 4306
            L+  YW +AY D  K+PG VFLFG+T D  +     VC+RV  + R +Y+LP             K +  + ++Y E  S +A    +E  R++ VTK +A   I  +VP   DYL V YD K   P L +D    + + IFGA T+ LE F+LD ++KGPCWL  +G + S    S C     +   K +++ ++K  P     L     N++T MN K++ NEI  I    HN  ++DR  P   F  +   LT P     P DLN ++A      YK++ + + + ER+L+S  L +   +D D+IV    +  QL ++  +  AL I  W + GRL+ S +  K         +E     GR++CDV+ SA E I+ RSY+ + L +++L  K ++    V   DL  ++     I +LI LT+ ++   + LM EL ++PLAL+IT ICGN + RTL GG+SERNE+LLLHAF+EK YIVPDK     ++   + D   S       +K+K  YAGGLVLEP +GLYE ++LLMDFNSLYPSII EYNICFTT+ +       D D+ +  L D   +     PGILP+++++LVE+R  VK+L+  P+LS E  +Q+ IRQ ALK+TANSMYGCLGF+ SRF A  LAALVT  GREIL NT+++++        K+N     D++YGDTDS+M+NT   N+  YD V KIG  IK+ VN+ YK ++L+IDGV   +LLL KKKYA++  +S+D S G L  +QE KGLDIVRRDW +L++ VGK +L  +L E+   E L  ++H  L+ I   +    + L  F+ITK LTR P+ Y+N    PHVQVALR+N      ++Y+  D V+Y+IC DGT+  A QRAY   E+ +S   E++KL +D NYYL HQ+HPVV R++E ++  DAS +AE LG+DP+K+    Q  + +NT   +     ++T +  R   C+P    C  C+ +          +P    N ++ +L   A +           +V  +L+  + + +  +Y     C    C +         N     L   + +  C +C SG +    +   L  QL Y RF+   GK+ L  K       ++  Q+  + V++ L+ S Y+ +    L A+   Q+ +
Sbjct:  362 LRFWYW-EAYEDPVKMPGEVFLFGRTADGKS-----VCLRVQNINRVLYLLPRQFLLDPISKEPTKQKVTVADIYKEFDSEVANQLKLEFFRSRKVTKSFAHHAIGIEVPQSCDYLEVHYDGKKPLPNLSADKKYNSIAHIFGATTNALERFLLDRKIKGPCWLQVTGFKVSPTPMSWCNTEVTLTEPKNVELVQDKGKPAPPPPLTLLSLNVRTSMNPKTSRNEICMISMLTHNRFHIDRPAPQPAFNRHMCALTRPAVVSWPLDLNFEMA-----KYKSTTVHKHDSERALLSWFLAQYQKIDADLIVTFDSMDCQLNVITDQIVALKIPQWSRMGRLRLSQSFGK-------RLLEHFV--GRMVCDVKRSAEECIRARSYDLQTLCKQVLKLK-ESERMEVNADDLLEMYEKGESITKLISLTMQDNSYLLRLMCELNIMPLALQITNICGNTMTRTLQGGRSERNEFLLLHAFHEKNYIVPDKKPVSKRSGAGDTDATLSGADATMQTKKKAAYAGGLVLEPMRGLYEKYVLLMDFNSLYPSIIQEYNICFTTVQQ-----PVDADE-LPTLPDSKTE-----PGILPLQLKRLVESRKEVKKLMAAPDLSPELQMQYHIRQMALKLTANSMYGCLGFAHSRFFAQHLAALVTHKGREILTNTQQLVQ--------KMN----YDVVYGDTDSLMINT---NITDYDQVYKIGHNIKQSVNKLYKQLELDIDGVFGCLLLLKKKKYAAIK-LSKD-SKGNLRREQEHKGLDIVRRDWSQLAVMVGKAVLDEVLSEKPLEEKLD-AVHAQLEKIKTQIAEGVVPLPLFVITKQLTRTPQEYANSASLPHVQVALRMNRERN--RRYKKGDMVDYVICLDGTTNAAMQRAYHLDELKTS---EDKKLQLDTNYYLGHQIHPVVTRMVEVLEGTDASRIAECLGMDPTKFRQNAQRTQRENTEQSEGESLLKTTLQLYRL--CEPFRFQCVTCKTE---QLMASAYRPG-PSNSHIAVLQQCAKSECQTAPIQYLASVRNQLQLSMRQYVQRFYKNWLVCDHPDCNF---------NTRTHSLRKKSHRPLCQKCRSGSLLRQYTERDLYNQLCYLRFMFDLGKQTLQQKPTLTPELEQAYQLLYETVDQQLQSSSYVIISLSKLFARSLAQMSL 1468

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BLAST of DNA polymerase vs. TrEMBL
Match: V4BGE0 (DNA polymerase (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_109334 PE=3 SV=1)

HSP 1 Score: 853.588 bits (2204), Expect = 0.000e+0
Identity = 565/1448 (39.02%), Postives = 811/1448 (56.01%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIEVE-DIYDVVNEETYEKLKEKRQLDNFIEGD--SEYMESGKEIFDES-DEE-----DIKIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPK------VISSSKIKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVVSAG-FATDTKLEEHKPL--------WETEEIED-ESSNDKYDPFENIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPK-------------DQAQMTEVYSEVKSILA-KHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLN--FXXXXXXXXXXXXXXSPPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDR-APPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKIT-GHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDK----AAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRK--CQHKTSIDFKMELEKPWL------CGNCNVELLYSHADAVN-VNKKLKEIIDRIIHIYYSCISTCQ---CGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLLTGKENLS 4183
            R RRQ+  +K  +     KLK+AK+ G   K EIE E  +Y++V+E+ Y ++  +RQ D++I  D  + Y+E G+EIFD+  DEE     D  IG K+K    N N+  P           +  + ++ SM   +S+  KK    ++     EL     EE+ +     K    K + ++P         S   +KP   K+ P  ++Q P     K         +K   P  +   + P + K E   V +D    E F+TN         T+ +++++           WE  + E  E   D +     +D S L L+           YW DAY D  K PG V+LFGK   ES +  V+ C+ V  ++RR+Y+LP+              +  M +VY+E    +A KH I   ++  VTK+YAF+ I+VP E++YL V+Y +  P LP+DL G+TFS IFGAN S LE+F++D +LKGP WL     +      S CK+           +  +    PP  I++LN++T+ N K++ NEI+   G IHN+  +D+ AP    FQ +F +L+ P D + P+D   KL+ E G N K  VL   NER+L++ LL K+H +DPD+I+GH + G+ L ++L R  A  I  W K GRLKRS+ +PK++ G    S  E+ A  GR++CD+++SA+ELI+ RSY+  +L+Q +L EK     S +   D+  +++SS  + QLI+LTL +S   + +M+EL ++PLAL+IT ICGN++ RTL GG+SERNEYLLLHAF EK ++VPDK       +  N   E   + +      KRKP YAGGLVLEPKKG Y+ FILL+DFNSLYPSII EYNICFTTI+R       + D+    L +L  K +   PGILP EIRKLVE+R  VKQL+   NLS E+ +Q+DIRQKALK+TANSMYGCLGFS SRF A  LAA+VT  GREIL+ T+ +++             + LD+IYGDTDS+M+NT   N    DTV K+G  +K EVN+ Y+ ++++IDGV + +LLL KKKYA+L+V     S G     QELKGLDIVRRDW  L+ E G  +++ IL  E S E++  +IH  L  + + +RN  IS   F ITK+LT+NPE+Y + +  PHVQVALR+NS GG  K+ R  DT+ YIIC DG++  A+QRAY P+E+      ++  L ID  YYL++Q+HPVV RL +PI+  DA+ +AE LGLDPS Y HA  HN+ ++     + T+E  R+ DC  L   C +  C  +   D      + ++      C N   E      D +  +  +L  +I + I  YY     C+   CG   + +          L+   G   C  C  GI+    S S L  QL +Y++L   ++ +S
Sbjct:    5 RSRRQKK-EKTGRAAAFEKLKRAKERGEKHKYEIEEEKSVYEIVDEDNYSEIVRQRQEDDWIIDDDGAGYVEDGREIFDDDMDEETVSKNDKNIGDKKK----NKNIVRPG----------TKPKANIKSMFAAASMVTKKKPEKDVSLADDELLGDLMEELGSS--QAKPLPVKINKNKPSNKAALNPFSVKPLKPRNIKQEPDHSIQRPQAPAIK--------IKKQHKPEPVRIKKEPVEIKPEP--VDEDSPMIEQFDTNMDDDDDVIQTENQVQQNGGANLEFVSSGWENVQSETVEPVGDIH-----VDSSKLPLVTNEEGEQIMRFYWLDAYEDPWKQPGTVYLFGKVFIESAESHVSCCVTVKNIDRRVYLLPRKNRYNMKTKEETEGEISMVDVYTEFNEQIADKHKIMKFKSMKVTKQYAFEKIEVPVESEYLEVRYAADLPALPTDLCGETFSHIFGANKSSLELFLIDRKLKGPGWLDLKTPQLPPGPVSWCKVEAVVTSPNHVTVLRDSLAPPPLVIMTLNLRTLPNPKTHQNEIIGAAGLIHNDYNMDKPAPKQNQFQQHFCVLSKPNDCIYPFDFKDKLSKE-GKNMKTEVL--PNERALLAFLLAKIHKIDPDLIIGHDIYGFDLDVMLHRINANKIPHWSKIGRLKRSV-MPKLSHGPGQRSHGEKSAMCGRMMCDIQISAKELIRSRSYDLTELVQHILHEK----RSEIDYDDIRNMYSSSKHLLQLIELTLVDSTFILRIMYELNIIPLALQITNICGNIMGRTLMGGRSERNEYLLLHAFTEKNFLVPDKEYKKKPVVHHNEDEEDLDTTKSKKSQGKRKPAYAGGLVLEPKKGFYDKFILLLDFNSLYPSIIQEYNICFTTINRTPVAQTNEEDE--EALPELPDKDLE--PGILPTEIRKLVESRKQVKQLMKVDNLSPEQKMQYDIRQKALKLTANSMYGCLGFSHSRFYAKPLAAMVTGKGREILLQTRDLVQ------------MMNLDVIYGDTDSIMINT---NSTDMDTVFKLGNKVKAEVNKLYRLLEIDIDGVFKSMLLLKKKKYAALSVSK--NSDGTYTTTQELKGLDIVRRDWSDLAKEAGNFVVSQILSGE-SREEIVENIHTKLIEVGEQVRNDGISTELFHITKSLTKNPEDYPDKKSLPHVQVALRLNSKGG--KKLRGGDTIPYIICEDGSNLPASQRAYHPEEL-----AKQETLKIDVKYYLSNQVHPVVSRLCDPIEGTDAAHLAECLGLDPSGYRHAVHHNDEEDALLGDQLTEE-ERYKDCDRLKFICPQPTCNKEIIFDSVFSGSEAYIECSLAKCTNPACE--SRPVDYLGRIKNQLTMVIRQHIKKYYEGWMKCEDTACGARTKKL---------PLMFQRGHPFCSACHRGILHLEYSDSALYTQLSFYQYLFDPEKAMS 1371

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BLAST of DNA polymerase vs. TrEMBL
Match: E7FB68 (DNA polymerase OS=Danio rerio OX=7955 GN=pola1 PE=1 SV=1)

HSP 1 Score: 848.195 bits (2190), Expect = 0.000e+0
Identity = 564/1517 (37.18%), Postives = 828/1517 (54.58%), Query Frame = 2

Query:   41 DTYG----RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQ--LDNFIEGDSEYMESGKEIFDESDEEDIKIGPKRKKSMKNANL-KNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSK------------IKPNEPKEMPQKTVQEPIKFVKKQIVFN-----KGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPF----------------ETNPVVSAGFATDT----------------KLEEHKPLWETEEIEDESSNDKYDPFENIDKSSLKLIYWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ------------AQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXS-PPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQG-GKFSK--RKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQH--NEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELEKPWL------CGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL----------LTGKENLSYKQKELLQMCSKY------VERVLERSDYMNVDFKSLMAKF 4288
            DT G    R RR++  +K+ +   L +LK+AK+ G  +K E+E    IYD V+EE Y K+  +RQ       +  + Y+E G+EIFDE  ++D  +GPK K++ K  +  KN KK+ +       +S KS+F                   +   +LS   ++++    L     E    +  P +I+  K            +KP  PKE+P+  V +P   V +    +       S E +K+ +  +  +   +   E+ I  D++DFDEP                 ET P+V     T+                 K+EE KP+    E++ +SS  +    E  D   +   YW DA+ D+   PGVVFLFGK   ES +  V+ C+ V  +ER +Y+LP++               M +VY E   I  K  I   ++KPVTK YAF+  D+P +++YL V+Y ++ P LPSDL G TFS +FG NTS LE F+L+ +++GPCWL  +  + S+   S CK+    +    I + K+ S PP  ++S+++KTV N K++ NEIV+I   +H+   LD+APP   FQ +F +++ P D V PYD    +  + G      V I   ER+L+   L K+H +DPD++VGH + G+ L +LLQR     +  W K GRL+R+  +PK+ G S   + E+ AT GRL+CD+E+SA+ELI+C+SY   +L+ ++L    KA    VP  ++   ++ S  +  L++LT  ++ + + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF+E+ +IVPDK         L  D+  + G GK +K  +K  YAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT++R    +   T++    + +L  +S+    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++             + L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L V    +  GK   KQELKGLDIVRRDWC L+ E G  ++  IL ++ + + +  +I  +L  I + + N  I L  F I K+LT+ P++Y + +  PHV VAL INS GG  K+ +A DTV Y+IC DG++  A+QRAY+ +++      ++  L++D  YYL+ Q+HPVV R+ EPI+ IDA  +A  LGLDPS +    Q   +EAD+         +  R+ DC+     C  C  +   D   E     L      C  C+V    S  D  V +  KL+  I R I  YYS    C+           C    R+L +   +    CP C    +KP  S   L  QL +YR++          LTG + L +K KE  +    Y       + +L  S Y  V+   L   F
Sbjct:   20 DTCGIAASRSRREKK-EKVGRKSALEQLKRAKK-GEKVKYEVEEFTSIYDEVDEEQYSKIVRERQDDDWIIDDDGTGYVEDGREIFDEELDDD-ALGPKSKQAAKGGDSKKNVKKSSVS----KPNSIKSMF----------MNSNVKKPAEKHVDLS---QDDLLGDILQDLHSEKSVVLTPPPIITLKKKKTLGSPMNPFSVKPQMPKELPEVHVSKPRPVVTRVPPADPSPRSAASVEPSKA-TAAQIKKPKIEEPEEEAIEFDEMDFDEPMEAENLEEEPVKEKAEPETKPIVKVEPKTEPQDKMLISGLVGGMGWEKMEEGKPIETPVEVQVDSS--QLPLVEGPDGDMVFRFYWLDAFEDQYNQPGVVFLFGKVWIESAEAHVSCCVAVKNIERTMYLLPREHKVNLATGEKGVAVGMMDVYKEFNEISEKFKIMKFKSKPVTKNYAFEIPDIPSQSEYLEVKYSAEIPSLPSDLKGTTFSHVFGTNTSSLEHFLLNRKIRGPCWLDVTTPQLSNQPISWCKVEAVAQKSDLISVVKDLSPPPLVVMSISLKTVQNPKTHQNEIVSIAALVHHTFPLDKAPPRPPFQTHFCVVSKPNDCVFPYDFKDAVRKKNGI-----VEIAGTERALLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLRRA-NMPKLGGRS--GFAEKSATCGRLVCDIEISAKELIRCKSYNLTELVSQIL----KAERPVVPPENIRNFYSDSTHLLYLLELTWMDAKLILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFHERDFIVPDKQFFKKAQQDLGEDEEGDSGKGKSNKTRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVERGATNTRKKTEEDEDEIPELPDQSLEM--GILPKEIRKLVERRRQVKQLMKEPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKEMVQ------------RMNLEVIYGDTDSIMINTNSTNL---EEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALMV--EPQGDGKYTTKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQ-NRDTIIENIQKHLIEIGEKVANGNIPLNMFEIHKSLTKEPQDYPDKKSLPHVHVALWINSQGG--KKVKAGDTVSYVICQDGSNLAASQRAYTLEQL-----QKQPGLNLDTQYYLSQQVHPVVGRICEPIEGIDAVLIATWLGLDPSHFRAQQQQREDEADDFLGAPAQLTDEERYRDCERFTFTCPDCGTENIYDNVFEGTGSTLQLSLKSC--CHVPCGGSPMDHQVQIGNKLQLDIRRHIRRYYSGWLLCE--------DQACRNRIRRLPIAFSRSGPICPACLRSTLKPEYSEKALYNQLSFYRYIFDWEYAINKVLTGDDKLKFKSKEWKEEMEVYKKLKGVTDNILATSGYSEVNLAKLFQAF 1464

[Close]

BLAST of DNA polymerase vs. TrEMBL
Match: E9QIM3 (DNA polymerase OS=Danio rerio OX=7955 GN=pola1 PE=1 SV=1)

HSP 1 Score: 838.18 bits (2164), Expect = 0.000e+0
Identity = 560/1500 (37.33%), Postives = 824/1500 (54.93%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEG--DSEYMESGKEIFDESDEEDIKIGPKRKKSMKNANLK-NPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSKIK----PNEP----KEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFE----------------TNPVVSAGFATDT----------------KLEEHKPLWETEEIEDESSNDKYDPFENIDKSSLKLIYWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ------------AQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQG-GKFSK--RKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQH--NEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELEKPWL------CGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL----------LTGKENLSYKQKELLQMCSKY------VERVLERSDYMNVDFKSLMAKF 4288
            R RR++  +K+ +   L +LK+AK+ G  +K E+E    IYD V+EE Y K+  +RQ D++I     + Y+E G+EIFDE  ++D  +GPK K++ K  + K N KK+ +       +S KS+F                   +   +LS   ++++    L     E    +  P +I+  K K    P  P     +MP+  +  P      +   +  S E +K+ +  +  +   +   E+ I  D++DFDEP E                T P+V     T+                 K+EE KP+    E++ +SS  +    E  D   +   YW DA+ D+   PGVVFLFGK   ES +  V+ C+ V  +ER +Y+LP++               M +VY E   I  K  I   ++KPVTK YAF+  D+P +++YL V+Y ++ P LPSDL G TFS +FG NTS LE F+L+ +++GPCWL  +  + S+   S CK+    +    I + K+ SPP   ++S+++KTV N K++ NEIV+I   +H+   LD+APP   FQ +F +++ P D V PYD    +  + G      V I   ER+L+   L K+H +DPD++VGH + G+ L +LLQR     +  W K GRL+R+  +PK+ G S   + E+ AT GRL+CD+E+SA+ELI+C+SY   +L+ ++L    KA    VP  ++   ++ S  +  L++LT  ++ + + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF+E+ +IVPDK         L  D+  + G GK +K  +K  YAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT++R    +   T++    + +L  +S+    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++             + L++IYGDTDS+M+NT   N+   + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L V    +  GK   KQELKGLDIVRRDWC L+ E G  ++  IL ++ + + +  +I  +L  I + + N  I L  F I K+LT+ P++Y + +  PHV VAL INS GG  K+ +A DTV Y+IC DG++  A+QRAY+ +++      ++  L++D  YYL+ Q+HPVV R+ EPI+ IDA  +A  LGLDPS +    Q   +EAD+         +  R+ DC+     C  C  +   D   E     L      C  C+V    S  D  V +  KL+  I R I  YYS    C+           C    R+L +   +    CP C    +KP  S   L  QL +YR++          LTG + L +K KE  +    Y       + +L  S Y  V+   L   F
Sbjct:   28 RSRREKK-EKVGRKSALEQLKRAKK-GEKVKYEVEEFTSIYDEVDEEQYSKIVRERQDDDWIIDDDGTGYVEDGREIFDEELDDD-ALGPKSKQAAKGGDSKKNVKKSSVS----KPNSIKSMF----------MNSNVKKPAEKHVDLS---QDDLLGDILQDLHSEKSVVLTPPPIITLKKKKTLGSPMNPFSVKPQMPKVKIPIPPADPSPR---SAASVEPSKA-TAAQIKKPKIEEPEEEAIEFDEMDFDEPMEAENLEEEPVKEKAEPETKPIVKVEPKTEPQDKMLISGLVGGMGWEKMEEGKPIETPVEVQVDSS--QLPLVEGPDGDMVFRFYWLDAFEDQYNQPGVVFLFGKVWIESAEAHVSCCVAVKNIERTMYLLPREHKVNLATGEKGVAVGMMDVYKEFNEISEKFKIMKFKSKPVTKNYAFEIPDIPSQSEYLEVKYSAEIPSLPSDLKGTTFSHVFGTNTSSLEHFLLNRKIRGPCWLDVTTPQLSNQPISWCKVEAVAQKSDLISVVKDLSPPPLVVMSISLKTVQNPKTHQNEIVSIAALVHHTFPLDKAPPRPPFQTHFCVVSKPNDCVFPYDFKDAVRKKNGI-----VEIAGTERALLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLRRA-NMPKLGGRSG--FAEKSATCGRLVCDIEISAKELIRCKSYNLTELVSQIL----KAERPVVPPENIRNFYSDSTHLLYLLELTWMDAKLILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFHERDFIVPDKQFFKKAQQDLGEDEEGDSGKGKSNKTRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVERGATNTRKKTEEDEDEIPELPDQSLEM--GILPKEIRKLVERRRQVKQLMKEPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKEMVQ------------RMNLEVIYGDTDSIMINTNSTNL---EEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALMV--EPQGDGKYTTKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQ-NRDTIIENIQKHLIEIGEKVANGNIPLNMFEIHKSLTKEPQDYPDKKSLPHVHVALWINSQGG--KKVKAGDTVSYVICQDGSNLAASQRAYTLEQL-----QKQPGLNLDTQYYLSQQVHPVVGRICEPIEGIDAVLIATWLGLDPSHFRAQQQQREDEADDFLGAPAQLTDEERYRDCERFTFTCPDCGTENIYDNVFEGTGSTLQLSLKSC--CHVPCGGSPMDHQVQIGNKLQLDIRRHIRRYYSGWLLCE--------DQACRNRIRRLPIAFSRSGPICPACLRSTLKPEYSEKALYNQLSFYRYIFDWEYAINKVLTGDDKLKFKSKEWKEEMEVYKKLKGVTDNILATSGYSEVNLAKLFQAF 1452

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BLAST of DNA polymerase vs. TrEMBL
Match: B1WBE2 (DNA polymerase OS=Xenopus laevis OX=8355 GN=LOC398200 PE=2 SV=1)

HSP 1 Score: 825.083 bits (2130), Expect = 0.000e+0
Identity = 559/1522 (36.73%), Postives = 825/1522 (54.20%), Query Frame = 2

Query:   29 MSEDDTYGRPR-RQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEG--DSEYMESGKEIFDESDEEDI--------KIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEE--------FKFDIHQPKVISSSK------IKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDC--IVLDDIDFDEPFETN----PVVSAGFATDTK---------LEEHKPLWETEEIEDESSNDKYDPFE------NIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ-------------AQMTEVYSEVKSILA-KHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALP-QNSQLEI--DQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPED-LAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY---HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSID-----FKMELEKPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFLL---------TGKENLSYKQKELLQ-------MCSKYVERVLERSDYMNVDFKSLM 4279
            MS+  ++   R R+  ++K  + + L +LK+AK  G  +K E+E V  IY+ V+E  Y KL   RQ D++I     + Y+E G+EIFD+  E++         K  PK K ++K +++  P      F  + S  +K+    +  S          +L      ++ P       P ++ KK++        F      PKV+ +S        KP  P    + +V   IK   K  + +         P  +E      Q K ED   +  DD DFDEP E +    PV S+   T  +         ++E K  + T    +ES  D+ D  E       +D S L L+           YW DAY D+   PGVV+LFGK   ES   +V+ C+ V  +ER +Y+LP++                M  VY E    +A K+ I   ++K V K YAF+  DVP  ++YL V+Y +  P+LP DL G+TFS +FG NTS LE+F+L  ++KGP WL     + SS   S CK+   +     + + K+ +PP   +LSL++KTV N K++ NEIVAI   +H+   LD+APP   FQ +F +L+   D + PYD N+ +  +  AN    + I   ER+L+   L K+H +DPD+IVGH + G+ L +LLQR  +  +  W K GRL+RS+ +PK+ G S   + ER A  GR++CD+E+SA+ELI+C+SY   +L+ ++L    KA    +P  ++   +N S  +  +++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF E  +IVPDK      Q + +E   D   +Q    S++K  YAGGLVLEPK G Y+ FILL+DFNSLYPSII EYNICFTT+ R    +    DQ    + +L H  +    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K E+N+ YK ++++IDG+ + +LLL KKKYA+L V       GK + KQELKGLDIVRRDWC+L+ + G  +++ IL ++  P D +  +I   L  I +++ N  + + ++ I KALT++P++Y + +  PHV VAL INS GG  ++ +A DT+ Y+IC DG++ +A+QRAY+ +++      ++  LSID  YYL+ Q+HPVV R+ EPID ID++ +A  LGLDPS++    H  Q  E D          +  ++ DC+    +C KC  +   D       +++E P L      E   S  D  + V+ KL   I R I  YYS    C+           C    R+L ++  +    C  C    ++       L  QL +YRF+L           ++   + +K+L Q            V++VL RS Y  V+   L 
Sbjct:    1 MSDSGSFAASRSRREKTEKSGRKEALERLKRAKA-GEKVKYEVEQVSSIYEEVDEAEYSKLVRDRQDDDWIVDDDGTGYVEDGREIFDDDLEDNALADSGKGAKGAPKDKTNVKKSSVSKPNNIKSMF--MASAVKKTTDKAVDLSKDDLLGDLLQDLKSQAVPITPP-------PVITLKKKKLAGSPLNPFSVPPTAPKVLPTSVKRLPAVTKPGHPAAQSKASVPRQIKKEPKAELISSAVG-----PLKVE-----AQVKEEDSGMVEFDDGDFDEPMEEDVEITPVDSSTIKTQAQSIKCVKEENIKEEKSSFITSATLNESCWDQIDEAEPMTTEIQVDSSHLPLVTGADGSQVFRFYWLDAYEDQYSQPGVVYLFGKVWIESADAYVSCCVSVKNIERTVYLLPRENRVQLSTGKDTGVPVSMMHVYQEFNEAVAEKYKIMKFKSKKVDKDYAFEIPDVPASSEYLEVRYSADSPQLPQDLKGETFSHVFGTNTSSLELFLLSRKIKGPSWLEIKSPQLSSQPMSWCKVEAVVTRPDQVSVVKDLAPPPVVVLSLSMKTVQNAKTHQNEIVAIAALVHHTFPLDKAPPQPPFQTHFCVLSKLNDCIFPYDYNEAVKQK-NAN----IEIALTERTLLGFFLAKIHKIDPDVIVGHDIYGFDLEVLLQRINSCKVPFWSKIGRLRRSV-MPKLGGRSG--FAERNAACGRIICDIEISAKELIRCKSYHLSELVHQIL----KAERVVIPPENIRNAYNDSVHLLYMLENTWIDAKFILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFTENNFIVPDKPVFKKMQQTTVEDNDDMGTDQNKNKSRKKAAYAGGLVLEPKVGFYDKFILLLDFNSLYPSIIQEYNICFTTVHREAPSTQKGEDQDE--IPELPHSDLEM--GILPREIRKLVERRRHVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTHQGREILLHTKEMVQ--------KMN----LEVIYGDTDSIMINTNCNNL---EEVFKLGNRVKSEINKSYKLLEIDIDGIFKSLLLLKKKKYAALTV--EPTGDGKYVTKQELKGLDIVRRDWCELAKQAGNYVISQILSDQ--PRDSIVENIQKKLTEIGENVTNGTVPITQYEINKALTKDPQDYPDKKSLPHVHVALWINSQGG--RKVKAGDTISYVICQDGSNLSASQRAYAQEQL-----QKQENLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHYQQDEENDALLGGPSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIE-PGLKRCSKPECDASPLDYVIQVHNKLLLDIRRYIKKYYSGWLVCE--------EKTCQNRTRRLPLSFSRNGPICQACSKATLRSEYPEKALYTQLCFYRFILDWDYALEKVVSEQERGHLKKKLFQESENQYKKLKSTVDQVLSRSGYSEVNLSKLF 1451

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BLAST of DNA polymerase vs. TrEMBL
Match: B7ZRF3 (DNA polymerase OS=Xenopus laevis OX=8355 GN=LOC398200 PE=2 SV=1)

HSP 1 Score: 823.928 bits (2127), Expect = 0.000e+0
Identity = 558/1522 (36.66%), Postives = 825/1522 (54.20%), Query Frame = 2

Query:   29 MSEDDTYGRPR-RQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEG--DSEYMESGKEIFDESDEEDI--------KIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEE--------FKFDIHQPKVISSSK------IKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDC--IVLDDIDFDEPFETN----PVVSAGFATDTK---------LEEHKPLWETEEIEDESSNDKYDPFE------NIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ-------------AQMTEVYSEVKSILA-KHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPP-FSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALP-QNSQLEI--DQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPED-LAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKY---HHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSID-----FKMELEKPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL---------LTGKENLSYKQKELLQ-------MCSKYVERVLERSDYMNVDFKSLM 4279
            MS+  ++   R R+  ++K  + + L +LK+AK  G  +K E+E V  IY+ V+E  Y KL   RQ D++I     + Y+E G+EIFD+  E++         K  PK K ++K +++  P      F  + S  +K+    +  S          +L      ++ P       P ++ KK++        F      PKV+ +S        KP  P    + +V   IK   K  + +         P  +E      Q K ED   +  DD DFDEP E +    PV S+   T  +         ++E K  + T    +ES  D+ D  E       +D S L L+           YW DAY D+   PGVV+LFGK   ES   +V+ C+ V  +ER +Y+LP++                M  VY E    +A K+ I   ++K V K YAF+  DVP  ++YL V+Y +  P+LP DL G+TFS +FG NTS LE+F+L  ++KGP WL     + SS   S CK+   +     + + K+ +PP   +LSL++KTV N K++ NEIVAI   +H+   LD+APP   FQ +F +L+   D + PYD N+ +  +  AN    + I   ER+L+   L K+H +DPD+IVGH + G+ L +LLQR  +  +  W K GRL+RS+ +PK+ G S   + ER A  GR++CD+E+SA+ELI+C+SY   +L+ ++L    KA    +P  ++   +N S  +  +++ T  ++   + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF E  +IVPDK      Q + +E   D   +Q    S++K  YAGGLVLEPK G Y+ FILL+DFNSLYPSII EYNICFTT+ R    +    DQ    + +L H  +    GILP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK++++        K+N    L++IYGDTDS+M+NT   N+   + V K+G  +K E+N+ YK ++++IDG+ + +LLL KKKYA+L V       GK + KQELKGLDIVRRDWC+L+ + G  +++ IL ++  P D +  +I   L  I +++ N  + + ++ I KALT++P++Y + +  PHV VAL INS GG  ++ +A DT+ Y+IC DG++ +A+QRAY+ +++      ++  LSID  YYL+ Q+HPVV R+ EPID ID++ +A  LGLDPS++    H  Q  E D          +  ++ DC+    +C KC  +   D       +++E P L      E   S  D  + V+ KL   I R I  YYS    C+           C    R+L ++  +    C  C    ++       L  QL +YRF+         +  ++   + +K+L Q            V++VL RS Y  V+   L 
Sbjct:    1 MSDSGSFAASRSRREKTEKSGRKEALERLKRAKA-GEKVKYEVEQVSSIYEEVDEAEYSKLVRDRQDDDWIVDDDGTGYVEDGREIFDDDLEDNALADSGKGAKGAPKDKTNVKKSSVSKPNNIKSMF--MASAVKKTTDKAVDLSKDDLLGDLLQDLKSQAVPITPP-------PVITLKKKKLAGSPLNPFSVPPTAPKVLPASVKRLPAVTKPGHPAAQSKASVPRQIKKEPKAELISSAVG-----PLKVE-----AQVKEEDSGMVEFDDGDFDEPMEEDVEITPVDSSTIKTQAQSIKCVKEENIKEEKSSFITSATLNESCWDQIDEAEPMTTEIQVDSSHLPLVTGADGSQVFRFYWLDAYEDQYSQPGVVYLFGKVWIESADAYVSCCVSVKNIERTVYLLPRENRVQLSTGKDTGVPVSMMHVYQEFNEAVAEKYKIMKFKSKKVDKDYAFEIPDVPASSEYLEVRYSADSPQLPQDLKGETFSHVFGTNTSSLELFLLSRKIKGPSWLEIKSPQLSSQPMSWCKVEAVVTRPDQVSVVKDLAPPPVVVLSLSMKTVQNAKTHQNEIVAIAALVHHTFPLDKAPPQPPFQTHFCVLSKLNDCIFPYDYNEAVKQK-NAN----IEIALTERTLLGFFLAKIHKIDPDVIVGHDIYGFDLEVLLQRINSCKVPFWSKIGRLRRSV-MPKLGGRSG--FAERNAACGRIICDIEISAKELIRCKSYHLSELVHQIL----KAERVVIPPENIRNAYNDSVHLLYMLENTWIDAKFILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFTENNFIVPDKPVFKKMQQTTVEDNDDMGTDQNKNKSRKKAAYAGGLVLEPKVGFYDKFILLLDFNSLYPSIIQEYNICFTTVHREAPSTQKGEDQDE--IPELPHSDLEM--GILPREIRKLVERRRHVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTHQGREILLHTKEMVQ--------KMN----LEVIYGDTDSIMINTNCNNL---EEVFKLGNRVKSEINKSYKLLEIDIDGIFKSLLLLKKKKYAALTV--EPTGDGKYVTKQELKGLDIVRRDWCELAKQAGNYVISQILSDQ--PRDSIVENIQKKLTEIGENVTNGTVPITQYEINKALTKDPQDYPDKKSLPHVHVALWINSQGG--RKVKAGDTISYVICQDGSNLSASQRAYAQEQL-----QKQENLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHYQQDEENDALLGGPSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIE-PGLKRCSKPECDASPLDYVIQVHNKLLLDIRRYIKKYYSGWLVCE--------EKTCQNRTRRLPLSFSRNGPICQACSKATLRSEYPEKALYTQLCFYRFIFDWDYALEKVVSEQERGHLKKKLFQESENQYKKLKSTVDQVLSRSGYSEVNLSKLF 1451

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BLAST of DNA polymerase vs. Ensembl Cavefish
Match: ENSAMXT00000007988.2 (pep primary_assembly:Astyanax_mexicanus-2.0:3:18939687:19010256:1 gene:ENSAMXG00000007751.2 transcript:ENSAMXT00000007988.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 740.339 bits (1910), Expect = 0.000e+0
Identity = 513/1427 (35.95%), Postives = 755/1427 (52.91%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEG--DSEYMESGKEIFDESDEEDIK---IGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSKIK----PNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVVSAGFATDTKLEEHKPLWETEE---------IEDESSNDKYDPFENIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ-------------AQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLN-FXXXXXXXXXXXXXXSPPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAA-ALPQNSQLEIDQSNEQGGKFSKRK---PTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPS---KYHHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKME----LEKPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLL 4162
            R RR++  +K+ +   L +LK+AK+ G  +K E+E +  +Y+ V+EE Y K+   RQ D++I     + Y+E G+EIFDE  E+++     G K  K+ K   +  P            +S KS+F                   +   +LS   ++++    L     E K  +  P VI+  K K    P  P  +  +T   P     KQ  F + SS    SP             + D +  D++DFDEP +             + E  +P+ + E            +E   D+      +D S L L+           YW DA+ D+   PGVV+LFGK   ES K  V+ C+ V  +ER +Y LP++                M +VY E  S+  K  I   ++K V K YAF+  DVP + +YL V+Y ++ P+LPSDL G TFS +FG NTS LE  +L  +++GPCWL       SS   S CK+    +K      ++    PP  ++S+++KTV N K++ NEIV++   IH +  LD+APP   +Q +F +++ P D + PYD N+ +  +     K  V I A ER+L+   L K+H +DPD+IVGH ++G+ L +LLQR     +  W K GRL+R+  +PK+ G     + E+ A  GRL+CDVEVSA+ELI+C+SY   +L  ++L    K   + V   ++  +++ S  +  L++LT  ++ + + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF+EK YIVPDK     PQ    E D+  + G   S +      YAGGLVL+PK G Y+ FILL+DFNSLYPSII E+NICFTT+ R    S   T+   + + +L    +    G+LP EIRKLVE R  VKQL+  P+L+ +  LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GRE+ +N                     LD+IYGDTDS+M+N+   N+   + VMK+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L V    +  G+   KQE KGLDIVRRDWC L+ E G  +L  IL ++ + + +  +I  +L  + + + +  I +  F I K    +P++Y + +  PHV VAL INS  G  ++ +A DT+ Y+IC DG++  A+QRAY+P+++      +++ LS+D  YYL+ Q+HPVV R+ EPI+ ID   +A  LGLDP          +  E+D          +  R+ DC+    +C  C  +   D   E    + +P L   C++    S  D  + ++ KL   I R I  YYS    C+                               +   +KP  S   L  QL +YR++ 
Sbjct:   26 RSRREKR-EKVGRKSALEQLKRAKK-GEKIKYEVEDISSVYEEVDEEQYSKMVRDRQDDDWIIDDDGTGYVEDGREIFDEELEDNVAEKGGGSKENKNAKKLAVSKP------------NSIKSMF----------MNSNVKRPAEKDVDLS---KDDLLGDILQDLHSE-KPVLTPPPVITLKKKKALGSPMNPFSVKSQT---PKVIFVKQFCFLRSSS---FSPP------------VGDSLDFDEMDFDEPMDLGAEEQKKVTVKVEAEP-EPIVKVESGMVGGSCWEKMEEEEADEAPVEVQVDSSQLPLVEGPDGEMVFRFYWLDAFEDQYNQPGVVYLFGKVWIESAKAHVSCCVAVKNIERTMYFLPRENKVNLQTGEVTDVPVGMMDVYQEFNSLSEKFKIMKFKSKKVEKNYAFEIPDVPTQCEYLEVRYSAEMPQLPSDLKGTTFSHVFGTNTSSLEHLLLSRKIRGPCWLDIKTPTLSSQPMSWCKVEAIALKSDLISVVKDLTPPPLVVMSISLKTVQNPKTHHNEIVSLAALIHYKFPLDKAPPRVPYQTHFCVVSKPNDCIYPYDFNEAVRKK-----KGIVEIAATERTLLGFFLAKMHKIDPDVIVGHDILGFDLEVLLQRITVCKVPFWSKIGRLRRA-NMPKLGGRGG--FAEKSAACGRLVCDVEVSAKELIRCKSYHLTELAAQIL----KTERAVVAPENIRNMYSDSPHLLYLLELTWMDAKLILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFHEKNYIVPDKQFFKKPQQDPGE-DEDVDVGKNKSGKVKKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQREATGSRKKTEDDFNEVPELPDPDLEM--GVLPKEIRKLVERRRQVKQLMKQPDLNSDLYLQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREVCMN---------------------LDVIYGDTDSIMINSNSTNL---EEVMKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALMV--EQQGDGRYTTKQEFKGLDIVRRDWCDLAKECGNYVLGQILSDQ-NRDTILENIQQHLIEVGEKVASGSIPVNMFEIHK----DPQDYPDKKSLPHVHVALWINSQSG--RKVKAGDTISYVICQDGSNLAASQRAYAPEQL-----QKQQGLSLDNQYYLSQQVHPVVGRICEPIEGIDGVLIATWLGLDPGQFRAQQRQQREEESDGLLGVPAQLTDEERYRDCERFSFFCPDCGTENIYDSVFEGTGSVLEPSLKRCCHIPCGGSPMDHHIKISNKLLLDIRRHIRKYYSGWLVCE-------------------------------DQSTLKPEYSEKALYNQLSFYRYIF 1321

[Close]

BLAST of DNA polymerase vs. Ensembl Cavefish
Match: pold1 (DNA polymerase delta 1, catalytic subunit [Source:NCBI gene;Acc:103023852])

HSP 1 Score: 187.963 bits (476), Expect = 9.743e-48
Identity = 184/662 (27.79%), Postives = 310/662 (46.83%), Query Frame = 2

Query: 1700 NSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIER----MATAGRLLCDV-EVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTI---DRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVK-QLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRY-KGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVA--LRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
            + +L    E+ L+      +  +DPDII G+ +  + L  LL R  AL +N +   GR++   ++ K +   +     R    +   GR+  D+ +V  R+  K RSY    +    L E+ +    S+ + DL     +    ++L    L ++ + + L+ +L  +   +E+  + G  +   LS G+  +    LL    ++  ++P                   +GG+       Y G  V+EP+KG Y   I  +DF+SLYPSI++ +N+C+TT+    +   L +   D       DL  KS  +  G+LP  +  L+ AR   K +L    +  K+++L  D RQ ALKI+ANS+YG  G    +    +++  VT  GR+++  TK+++E   +K +          ++YGDTDSVMV  G+  V +    M +G+   E V+  +   I+L  + V    LL+NKK+YA L   S  +   K+    + KG++ VRRD C L       ++   L++ L   D   ++ +  + ISD + N +I + + +ITK LTR  + Y+  Q   HV++A  +R   AG +       D V Y+I        A  ++  P  VL      E  + ID  YYL  QL   + R+ EPI
Sbjct:  370 SQILCFTQEKQLLQSWAEFVRTVDPDIITGYNIQNFDLPYLLNRAAALKVNLFPYLGRVRGIKSILKDSSFQSKQMGRRENKTVNMEGRVQFDLLQVLLRDY-KLRSYTLNAVSFHFLQEQKEDVQHSI-ITDLQN--GNEQTRRRLAVYCLKDAYLPLRLLQKLMCVINYMEMARVTGVPLTYLLSRGQQIKVVSQLLRQAMKQDLVMP---------------VVKTEGGE------DYTGATVIEPEKGYYSIPIATLDFSSLYPSIMMAHNLCYTTLLQKGQADKLGLSAEDFIRTPTGDLFVKSSVR-KGLLPEILENLLSARKRAKAELKKETDPFKKQVL--DGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEQTKQLVE---SKYTIANGYKADAKVVYGDTDSVMVKLGVDTVQE---AMTVGREAAEWVSSHFVPPIKLEFEKVYHPYLLINKKRYAGLYFSSSAEHHDKM----DCKGIETVRRDNCPLVAN----LINTCLQKILIDRDPDGAVAHAKEVISDLLCN-RIDISQLVITKELTRTAQEYAGRQA--HVELAERMRKRDAGSAPN---LGDRVPYVIIKAAKGVAAYMKSEDPIYVL------ENNIPIDTQYYLEQQLSKPLMRIFEPI 977

[Close]

BLAST of DNA polymerase vs. Ensembl Cavefish
Match: pold1 (DNA polymerase delta 1, catalytic subunit [Source:NCBI gene;Acc:103023852])

HSP 1 Score: 187.578 bits (475), Expect = 1.266e-47
Identity = 184/662 (27.79%), Postives = 310/662 (46.83%), Query Frame = 2

Query: 1700 NSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIER----MATAGRLLCDV-EVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTI---DRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVK-QLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRY-KGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVA--LRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
            + +L    E+ L+      +  +DPDII G+ +  + L  LL R  AL +N +   GR++   ++ K +   +     R    +   GR+  D+ +V  R+  K RSY    +    L E+ +    S+ + DL     +    ++L    L ++ + + L+ +L  +   +E+  + G  +   LS G+  +    LL    ++  ++P                   +GG+       Y G  V+EP+KG Y   I  +DF+SLYPSI++ +N+C+TT+    +   L +   D       DL  KS  +  G+LP  +  L+ AR   K +L    +  K+++L  D RQ ALKI+ANS+YG  G    +    +++  VT  GR+++  TK+++E   +K +          ++YGDTDSVMV  G+  V +    M +G+   E V+  +   I+L  + V    LL+NKK+YA L   S  +   K+    + KG++ VRRD C L       ++   L++ L   D   ++ +  + ISD + N +I + + +ITK LTR  + Y+  Q   HV++A  +R   AG +       D V Y+I        A  ++  P  VL      E  + ID  YYL  QL   + R+ EPI
Sbjct:  387 SQILCFTQEKQLLQSWAEFVRTVDPDIITGYNIQNFDLPYLLNRAAALKVNLFPYLGRVRGIKSILKDSSFQSKQMGRRENKTVNMEGRVQFDLLQVLLRDY-KLRSYTLNAVSFHFLQEQKEDVQHSI-ITDLQN--GNEQTRRRLAVYCLKDAYLPLRLLQKLMCVINYMEMARVTGVPLTYLLSRGQQIKVVSQLLRQAMKQDLVMP---------------VVKTEGGE------DYTGATVIEPEKGYYSIPIATLDFSSLYPSIMMAHNLCYTTLLQKGQADKLGLSAEDFIRTPTGDLFVKSSVR-KGLLPEILENLLSARKRAKAELKKETDPFKKQVL--DGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEQTKQLVE---SKYTIANGYKADAKVVYGDTDSVMVKLGVDTVQE---AMTVGREAAEWVSSHFVPPIKLEFEKVYHPYLLINKKRYAGLYFSSSAEHHDKM----DCKGIETVRRDNCPLVAN----LINTCLQKILIDRDPDGAVAHAKEVISDLLCN-RIDISQLVITKELTRTAQEYAGRQA--HVELAERMRKRDAGSAPN---LGDRVPYVIIKAAKGVAAYMKSEDPIYVL------ENNIPIDTQYYLEQQLSKPLMRIFEPI 994

[Close]

BLAST of DNA polymerase vs. Ensembl Cavefish
Match: pold1 (DNA polymerase delta 1, catalytic subunit [Source:NCBI gene;Acc:103023852])

HSP 1 Score: 141.739 bits (356), Expect = 1.633e-33
Identity = 126/402 (31.34%), Postives = 199/402 (49.50%), Query Frame = 2

Query: 2465 MDFNSLYPSIILEYNICFTTI---DRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVK-QLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRY-KGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVA--LRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
            +DF+SLYPSI++ +N+C+TT+    +   L +   D       DL  KS  +  G+LP  +  L+ AR   K +L    +  K+++L  D RQ ALKI+ANS+YG  G    +    +++  VT  GR+++  TK+++E   +K +          ++YGDTDSVMV  G+  V +    M +G+   E V+  +   I+L  + V    LL+NKK+YA L   S  +   K+    + KG++ VRRD C L       ++   L++ L   D   ++ +  + ISD + N +I + + +ITK LTR  + Y+  Q   HV++A  +R   AG +       D V Y+I            AY   EV S    E   +     YYL  QL   + R+ EPI
Sbjct:  582 LDFSSLYPSIMMAHNLCYTTLLQKGQADKLGLSAEDFIRTPTGDLFVKSSVRK-GLLPEILENLLSARKRAKAELKKETDPFKKQVL--DGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEQTKQLVE---SKYTIANGYKADAKVVYGDTDSVMVKLGVDTVQE---AMTVGREAAEWVSSHFVPPIKLEFEKVYHPYLLINKKRYAGLYFSSSAEHHDKM----DCKGIETVRRDNCPLVAN----LINTCLQKILIDRDPDGAVAHAKEVISDLLCN-RIDISQLVITKELTRTAQEYAGRQA--HVELAERMRKRDAGSAPN---LGDRVPYVIIKAAKGVA----AYMKSEVGSVFLYESDPIY----YYLEQQLSKPLMRIFEPI 952

[Close]

BLAST of DNA polymerase vs. Ensembl Cavefish
Match: rev3l (REV3 like, DNA directed polymerase zeta catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-050302-55])

HSP 1 Score: 110.538 bits (275), Expect = 1.076e-23
Identity = 151/680 (22.21%), Postives = 268/680 (39.41%), Query Frame = 2

Query: 1718 ANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMAT---AGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNIC----LMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYI--VPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRC--KYLSVGDTDQ------AMHILMDLSHK-----------------SVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQH--DIRQKALKITANSMYG--CLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVN-RRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLI 3640
            A E+ L   + N +   DPDI+VG+ +     G LLQR  AL ++   +  R+       + T   +    + M+     GR+  ++    +      +Y   ++   +L ++F  +        L   F+    + +     +D  +  +C    L+ +  ++    E   + G      L+ G   R E ++L       YI   P       Q +   I                    LV+EP+   Y N ++++DF SLYPSI++ YN CF+T   C     S+G +D+      ++ +  DL ++                 SV K  G+LP  + ++++ R  VK ++   +   +K L    D RQ  LK+ AN  +G     FS  R  + ++   +    RE L    K++ +                ++YGDTDS+ V        Q     KIG  I E V     K I+L  + V    +L  KK+Y      + D+         + KG++ VRRD C    ++ +R + ++ E      D++  +  Y++     +   K S+      K   R   +Y      P +++  R+ S    + + R  + V Y+I          Q    P EVL     ++  L ++  YY+  Q+ P V R+ 
Sbjct: 2119 AEEKELFEEVCNIMRRYDPDILVGYEVQMRSWGYLLQRASALGVDLCQQLSRVPGDAKENRFTADKDEYGADTMSEIHIVGRITINLWRIMKTEAALNNYSFENVAFHLLHQRFPLYSPRT----LSDWFDHKTHLYRW--KVVDHYVSRVCGVVQLLRQQDIVGRTSEFARVFGIQFYHVLTRGSQYRVESMMLRVAKPMNYIPVTPSTQQRAQQRAPQCI-------------------PLVMEPESRFYSNSVVVLDFQSLYPSIVIAYNYCFST---CLGHVESLGTSDEFRFGCTSLRVPPDLLYQLRNDITVSPNGIAFVKASVRK--GVLPRMLEEILQTRFMVKGVMK--SYRDDKALHRLLDARQLGLKLIANVTFGYTSANFS-GRMPSVEVGDSIVHKARETLERAIKLVNE---------TKKWGARVVYGDTDSMFVLLKGATKEQ---AFKIGHEIAEAVTATNPKPIKLKFEKVYLPCVLQTKKRYVGYMYETVDQKDPVF----DAKGIETVRRDGCPAVAKILERSVKLLFET----RDISL-VKQYVQRQCVKVLEAKASMQDLTFAKEY-RGSGSYRPGACIPALELTRRMMSYDRRL-EPRVGERVPYVIVYGTPGVPLIQLVRRPLEVL-----QDPSLRLNATYYITKQILPPVARIF 2737

[Close]

BLAST of DNA polymerase vs. Ensembl Sea Lamprey
Match: pold1 (polymerase (DNA directed), delta 1, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-060429-1])

HSP 1 Score: 167.933 bits (424), Expect = 3.165e-42
Identity = 178/651 (27.34%), Postives = 302/651 (46.39%), Query Frame = 2

Query: 1766 LDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIER----MATAGRLLCDV-EVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP------------GILPIEIRKLVEARN---AVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAAL-VTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRY-KGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAG-GSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
            +DPDII G+ +  + L  LL R   L ++T+   GR+    ++ K +   +     R    +   GR+  D+ +V  R+  K RSY    +    L E+ +    S+ + DL     +    ++L    L ++++ + L+ +L  +   +E+  + G  +   L+ G+  +    LL    ++  ++P      P+ ++                   YAG  V+EP KG Y   I  +DF+SLYPSI++ +N+C+TT+     L  G  +      + LS +   K P            G+LP  +  L+ AR    A ++L N  +  K+K+L  D RQ ALKI+ANS+YG  G    +    +++   VT  GR+++  TK ++E   ++ + +        +IYGDTDSVMV   +  V +    M++G+     V+  +   I+L  + V    LL+NKK+YA L   S  ++  K+    + KG++ VRRD   L       ++   L++ L   D   ++ +   +ISD + N +I + + +ITK LTR  + Y+  Q   HV++A R+     GS       D V Y+I        A  ++  P  VL      E  + ID  YYL  QL   + R+ EPI
Sbjct:  400 VDPDIITGYNIQNFDLPYLLNRASTLRVSTFSFLGRITSMRSVIKESSFQSKQMGRRDNKVINLEGRVTFDLLQVLLRDY-KLRSYTLNAVSFHFLQEQKEDVQHSI-ITDLQN--GNEQTRRRLAVYCLKDAMLPLRLLEKLMCVINYMEMARVTGVPLSYLLTRGQQIKVVSQLLRQAMKQDLLLP---VVKPEGNE------------------DYAGATVIEPIKGYYTVPIATLDFSSLYPSIMMAHNLCYTTL-----LQKGVVEN-----LGLSAEDFIKTPSGDHFVKSSVRKGLLPEILENLLSARKKRRAKEELKNETDPFKQKVL--DGRQLALKISANSVYGFTGAQVGKLPCLEISQQSVTGFGRQMIETTKNLVE---SRYTTENGQKADAKVIYGDTDSVMVKFSVKTVAEG---MEMGREAAAWVSSHFIPPIKLEFEKVYYPYLLINKKRYAGLYFSSSSETHDKM----DCKGIETVRRDNSPLV----ANLINTCLQKILIDRDPDGAVDHAKDTISDLLCN-RIDISQLVITKELTRTADEYAGKQA--HVELAERMRKRDPGSAPNL--GDRVPYVIVKATKGVAAYMKSEDPIYVL------ENNIPIDTQYYLEQQLAKPLLRIFEPI 988

[Close]

BLAST of DNA polymerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006446.1 (pep scaffold:Pmarinus_7.0:GL477096:156518:193524:1 gene:ENSPMAG00000005826.1 transcript:ENSPMAT00000006446.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.4774 bits (171), Expect = 6.870e-13
Identity = 69/281 (24.56%), Postives = 119/281 (42.35%), Query Frame = 2

Query: 1718 ANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSW--IERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGI--KQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTT-IDRCKYL 2545
            + E  L   L   +H  DPDI++G+ +     G LLQR  AL  +      R+K      ++    N        +   GR++ ++    R  +    Y   ++   +L E++  F        L   F++  G    +++D  +   + NI L+++L  +    E+  + G      LS G   R E ++L       YI     A  P   Q    ++ E               LV+EP+   Y + +L++DF SLYPSII+ YN C++T + R ++L
Sbjct:   88 SKEDQLFHELEQIVHRFDPDILLGYEVQMLSWGYLLQRAAALKRDFKSTISRMKVEPTETQVGVGKNEEDDDFPDIHIGGRVVLNLWSQMRSEVTLNIYSFENVAYHVLHERYPLFNFRT----LSDWFDNKTGPFRWKMVDYYVCRVVGNIKLLNQLDFIGRTSELARLFGIQFHEVLSRGSQFRVESMMLRVAKPLNYI-----AVSPSVQQRAHMRAAE------------CLPLVMEPESRFYSSPVLVLDFQSLYPSIIIAYNYCYSTCLGRVEHL 347

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BLAST of DNA polymerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009864.1 (pep scaffold:Pmarinus_7.0:GL480102:12343:24944:1 gene:ENSPMAG00000008922.1 transcript:ENSPMAT00000009864.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.9214 bits (141), Expect = 6.065e-9
Identity = 79/349 (22.64%), Postives = 152/349 (43.55%), Query Frame = 2

Query: 2618 GILPIEIRKLVEARNAVKQLLNN--PNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKG-IQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDM 3655
            G+LP  + ++++ R  VK  + +   + +  +LL    RQ  LK+ AN  +G   ++ + F + ++  +    G  I+   ++ +E    +++          ++YGDTDS+ V     +  Q     + G+ I   V       I+L  + V    +L  KK+Y      S ++         + KG++ VRRD C    +V +R + ++ +E    +D++  +  Y++     +   + S+   I  K   R    Y      P + VA R+  A     + RA + V Y+I +        Q    P+E+L     +E  L I+  YY++ Q+ P + RL+  I +
Sbjct:   10 GVLPRMLEEILQTRIMVKHCMKDYRGDGALTRLLH--ARQLGLKLIANVTFG---YTAAHF-SGRMPCVEEQVGDSIVHKARETLERAIKQVNETKEWGA--RVVYGDTDSMFVLLEGASKEQ---AFRTGKEIAAAVTAANPSPIKLKFEKVYLPCVLQTKKRYVGYMYESLEQKDPVY----DAKGIETVRRDGCPAVAKVLERSIKLLFDE----KDIS-RVKQYVQRQCMKILEGRASMQDLIFAKEY-RGRSGYKPGACVPALHVARRMF-ACDRRSEPRAGERVPYVIVHGAPGLPLIQLVRRPQELL-----QEPSLLINAPYYVSKQILPPLDRLLSLIGV 331

[Close]

BLAST of DNA polymerase vs. Ensembl Yeast
Match: POL1 (Catalytic subunit of the DNA polymerase I alpha-primase complex; required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis [Source:SGD;Acc:S000005046])

HSP 1 Score: 478.789 bits (1231), Expect = 5.648e-145
Identity = 375/1186 (31.62%), Postives = 595/1186 (50.17%), Query Frame = 2

Query:  785 PFETNPVVSAGFATDTKLEEHKPLWETEEIEDESSNDKYDPFENIDKSSLKLIYWFDAYHDKKIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQAQMTEVYSEVKSILA-KHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPE-----LPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSS-NQFSTCKLNFXXXXXXXXXXXXXXS-PPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGR-LKRSIALPKITGHSNTSWIERMAT---AGRLLCDV--EVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLM-----HELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGK--FSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP-----GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICN--------DGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHH---ANQHNEADNTYSKQEST-DEANRFIDCKPLPIYCRKCQHK------TSIDFKMELEKPWLCGNCNVELLYSHADAVNVNKKLKEIIDRIIHIYYSCISTCQ---CGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLLTGKENLSYKQKEL 4201
            PF T P    G      L   K L    ++   + N K +   + +  + ++ +W D     ++   + LFGK + +     V+  ++++GL R ++ LP++    T+++ E+  +L  K+G++++R KP   KY+F+  D+P E+DYL V    + P+     +PSDLS  TF  +FG N++  E F++  R+ GPCWL   G + +S    S C +   +   + I     K+ P    LSL+I+T+MN K N  EIV+I    +  I LD   P  +  ++   L  P            LA+         V +  NE++++SC    L   DPD+I+GH L    L +L  R   LNI T+   GR L+R+   P+  G  N++      +   +GRL+CD+  E+      KC+S++  ++ Q    ++ K               NS       + + L E++ N C++     + +Q+L L  ++T + GN   +TL G ++ RNEY+LLH F+   +IVPDK       S+ +  + NE+      + +K  Y GGLV EP+KGL++N++L+MDFNSLYPSII E+NICFTT+DR K     D D+   +           PP     G+LP  +  LV+ R  VK+++        K +Q DIRQ+ALK+TANSMYGCLG+  SRF A  LA LVT  GREIL+NT+++ E            ++ L ++YGDTDSVM++TG  N   Y   +KIG   K  VN RY+ ++++ID V +++LL  KKKYA+L V      +G  +L  E+KGLD+ RR++C LS +V   +L  IL ++  PE+    +++YL+ I   +    I + K+ I   L+++P+ Y   +  P VQVALR+  AG  +K   A   + ++I          D  + +  +RA++  EV+  S      L  D  YYL  Q+   V RL+E ID  +   ++E LGLD  KY      N + E  N     E+T  +  RF D   L + C  C  +       S ++         C +C  E L++    + +  +++  I   I +YY+    C    CG + R  V++      K  +  G   C    +G+M+   S   L  QL Y+  L   ++N   K++EL
Sbjct:  306 PFVTAPGTPIGIKG---LTPSKSLQSNTDVATLAVNVKKEDVVDPETDTFQM-FWLDYC---EVNNTLILFGKVKLKD-DNCVSAMVQINGLCRELFFLPREGKTPTDIHEEIIPLLMDKYGLDNIRAKPQKMKYSFELPDIPSESDYLKVLLPYQTPKSSRDTIPSDLSSDTFYHVFGGNSNIFESFVIQNRIMGPCWLDIKGADFNSIRNASHCAVEVSVDKPQNITPTTTKTMPNLRCLSLSIQTLMNPKENKQEIVSITLSAYRNISLDSPIPENIKPDDLCTLVRPPQST---SFPLGLAALAKQKLPGRVRLFNNEKAMLSCFCAMLKVEDPDVIIGHRLQNVYLDVLAHRMHDLNIPTFSSIGRRLRRT--WPEKFGRGNSNMNHFFISDICSGRLICDIANEMGQSLTPKCQSWDLSEMYQVTCEKEHKPLDIDYQNPQYQNDVNS-------MTMALQENITN-CMISAEVSYRIQLLTLTKQLTNLAGNAWAQTLGGTRAGRNEYILLHEFSRNGFIVPDKEG---NRSRAQKQRQNEENADAPVNSKKAKYQGGLVFEPEKGLHKNYVLVMDFNSLYPSIIQEFNICFTTVDRNK----EDIDELPSV-----------PPSEVDQGVLPRLLANLVDRRREVKKVMKT-ETDPHKRVQCDIRQQALKLTANSMYGCLGYVNSRFYAKPLAMLVTNKGREILMNTRQLAE------------SMNLLVVYGDTDSVMIDTGCDN---YADAIKIGLGFKRLVNERYRLLEIDIDNVFKKLLLHAKKKYAALTVNLDKNGNGTTVL--EVKGLDMKRREFCPLSRDVSIHVLNTILSDK-DPEEALQEVYDYLEDIRIKVETNNIRIDKYKINMKLSKDPKAYPGGKNMPAVQVALRMRKAGRVVK---AGSVITFVITKQDEIDNAADTPALSVAERAHALNEVMIKSNN----LIPDPQYYLEKQIFAPVERLLERIDSFNVVRLSEALGLDSKKYFRREGGNNNGEDINNLQPLETTITDVERFKDTVTLELSCPSCDKRFPFGGIVSSNYYRVSYNGLQCKHC--EQLFT---PLQLTSQIEHSIRAHISLYYAGWLQCDDSTCGIVTR-QVSVFG----KRCLNDG---C----TGVMRYKYSDKQLYNQLLYFDSLFDCEKN---KKQEL 1406

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BLAST of DNA polymerase vs. Ensembl Yeast
Match: POL3 (Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER) [Source:SGD;Acc:S000002260])

HSP 1 Score: 197.208 bits (500), Expect = 1.545e-51
Identity = 195/661 (29.50%), Postives = 305/661 (46.14%), Query Frame = 2

Query: 1706 VLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIER----MATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVG------DTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARN-AVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDG-CAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYK-GIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
            +   A E  ++S   N +  +DPD+I+G+    + +  LL R +AL +N +  FGRLK      K +  S+ ++  R    +   GRL  D+    +   K RSY    +    L E+ K  V    + DL      S   ++L    L ++ + + LM +L  L    E+  + G      L+ G+  +    L     E   ++P+        SQ   DQ              Y G  V+EP +G Y+  I  +DFNSLYPSI++ +N+C+TT+  C   +V       D D  +    D    +  +  GILPI + +L+ AR  A K L +  +  K  +L    RQ ALKI+ANS+YG  G +  +     +++ VT +GR +++ TK  +++  C K   K +  V    +YGDTDSVMV  G  ++ +    M +G    + V+  +K  I L  +      LL+NKK+YA L   + DK       K + KGL  VRRD C L   V  ++L  IL E      LAF     ++   +D+ + ++ + K II+K L     NY+NP  QPH  +A R+    G        D V+Y+I   G ++    RA  P  VL      E  + +D  YYL +QL   +  ++ PI
Sbjct:  373 IFSHATEEEMLSNWRNFIIKVDPDVIIGYNTTNFDIPYLLNRAKALKVNDFPYFGRLKTVKQEIKESVFSSKAYGTRETKNVNIDGRLQLDLLQFIQREYKLRSYTLNAVSAHFLGEQ-KEDVHYSIISDLQN--GDSETRRRLAVYCLKDAYLPLRLMEKLMALVNYTEMARVTGVPFSYLLARGQQIKVVSQLFRKCLEIDTVIPN------MQSQASDDQ--------------YEGATVIEPIRGYYDVPIATLDFNSLYPSIMMAHNLCYTTL--CNKATVERLNLKIDEDYVITPNGDY-FVTTKRRRGILPIILDELISARKRAKKDLRDEKDPFKRDVLNG--RQLALKISANSVYGFTGATVGKLPCLAISSSVTAYGRTMILKTKTAVQEKYCIKNGYKHDAVV----VYGDTDSVMVKFGTTDLKE---AMDLGTEAAKYVSTLFKHPINLEFEKAYFPYLLINKKRYAGLFWTNPDKFD-----KLDQKGLASVRRDSCSLVSIVMNKVLKKILIERNVDGALAF-----VRETINDILHNRVDISKLIISKTLA---PNYTNP--QPHAVLAERMKRREGVGPN--VGDRVDYVII--GGNDKLYNRAEDPLFVL------ENNIQVDSRYYLTNQLQNPIISIVAPI 973

[Close]

BLAST of DNA polymerase vs. Ensembl Yeast
Match: REV3 (Catalytic subunit of DNA polymerase zeta; involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair; forms a complex with Rev7p, Pol31p and Pol32p [Source:SGD;Acc:S000006088])

HSP 1 Score: 122.479 bits (306), Expect = 2.330e-28
Identity = 158/677 (23.34%), Postives = 288/677 (42.54%), Query Frame = 2

Query: 1706 VLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALN-INTWYKFGRLKRSIA--LPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIV--PDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTT-IDRCKYLSVGDTDQAM-------HILMDLSHKSVAKPPGIL--PIEIRK---------LVEARNAVKQLLN---NPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQS-RFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRY-KGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
            V+   +E  +   L + +  LDPDI+ G  +  +  G +++RCQ ++  +   +  R+K  I   L    G++++S I  M T GR + ++  + R  +    Y        +L ++   F S   + ++     S+  +K +++  L  + +NI L+ +   +   +E   + G         G   + E  L+     + +I+  P K                       K+K      LV+EP+   Y++ ++++DF SLYPSI++ YN C++T I R + +++ + +  +       +IL  L +     P G++     +RK         +++ R  +K+ +N   + N + ++LL +  +Q ALK+ AN  YG    S S R   + LA  +   GRE L     IIE          +      ++YGDTDS+ V        +      IG  + E V +   K I L  + V    +L++KK+Y   +     +S  + +   + KG++ VRRD     I   ++I+   +      +DL+  I  YL++    ++  K+S   F   K +               V V  RIN    +  QY  K+ + Y++      +   +R  SP+E L     E   L +D  YY+   L P + RL   I
Sbjct:  739 VMFYESEFEMFEALTDLVLLLDPDILSGFEIHNFSWGYIIERCQKIHQFDIVRELARVKCQIKTKLSDTWGYAHSSGI--MIT-GRHMINIWRALRSDVNLTQYTIESAAFNILHKRLPHF-SFESLTNMWNAKKSTTELKTVLNYWLSRAQINIQLLRKQDYIARNIEQARLIGIDFHSVYYRGSQFKVESFLIRICKSESFILLSPGKKDV-------------------RKQKALECVPLVMEPESAFYKSPLIVLDFQSLYPSIMIGYNYCYSTMIGRVREINLTENNLGVSKFSLPRNILALLKNDVTIAPNGVVYAKTSVRKSTLSKMLTDILDVRVMIKKTMNEIGDDNTTLKRLLNN--KQLALKLLANVTYGYTSASFSGRMPCSDLADSIVQTGRETLEKAIDIIEK---------DETWNAKVVYGDTDSLFVYLPGKTAIE---AFSIGHAMAERVTQNNPKPIFLKFEKVYHPSILISKKRYVGFSY----ESPSQTLPIFDAKGIETVRRD----GIPAQQKIIEKCIRLLFQTKDLS-KIKKYLQNEFFKIQIGKVSAQDFCFAKEVKLGAYKSEKTAPAGAVVVKRRINEDHRAEPQY--KERIPYLVVKGKQGQLLRERCVSPEEFL-----EGENLELDSEYYINKILIPPLDRLFNLI 1362

[Close]

BLAST of DNA polymerase vs. Ensembl Nematostella
Match: EDO39342 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A7SAB6])

HSP 1 Score: 595.89 bits (1535), Expect = 0.000e+0
Identity = 414/1174 (35.26%), Postives = 612/1174 (52.13%), Query Frame = 2

Query:  941 IYWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQ------------AQMTEVYSEV-KSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKN-SVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKIT------GHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNK--KKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTS---ETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHA--NQHNEADNTYSKQESTDEANRFIDCKPLPIYCRK--CQHKTSIDFKMELEK------PWLCGNC-NVELLYSHADAVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARK--LLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYY-------RFLLTGKEN-------LSYKQ-----KELLQMCSKYVERVLERSDYMNVDFKSLMAKF 4288
             YWFDAY D+ K PGVV+LFGK + ES  K+V+ C+ +  ++R I++LP+++                +VY E  + I +K+ I     + V K YAF   D+P  ++YL V+Y   + +                                  WLS          F  C L F +             P   I +L++KT+MN++++  E++A+   +H E+ +D+A P   FQ  F +L       M   L+      W    ++  + + A+ER+L++ ++ K+H +DPD++VGH + G+ L ILL R  A  I  W + GRLKRSI +PK+       GH+    ++   T GRLLCDV++S+RELI+ +SY+  +L + +L    +         D+  ++N+S  +  L++LT  +SL+ + +M+EL VLPLA +IT I GN++ RTL GG+S+RNE+LLLHAF+EK YI PDK+    Q  + E D  +    K  +RKP YAGGLVLEPKKG Y+ FILL+DFNSLYPSII EYNICFTTIDR    S  D +  +  L D+      + PGILP EIRKLVE R  VK ++   +   +K LQ+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL+ TK +++             + LD+IYGDTDS+M+NT   N      V K+G  ++         + L +   +R + LL+    +YA++ +   +   G +   +E+KGLDIVRRDWC L+ + G  +L+ IL  + S E +  ++H++L +I +D++  K+ L K++I K LT+ P +Y + +  PHV VAL + S     ++    DT+ Y+IC+        T     +     L  + T    L + + Y +++        + +PID  D++ +AE LGLDPS Y HA     +EAD     Q    +  RF DC  L + C++  C  +T+I+   EL K      P L   C   E LYS A  +N    L  II + I  YY+    C+           C+   R+  L+   G   CP C    M P+ S + L  QL +Y       R L T K+N        SY +     K         ++R++E + Y  VD   L   F
Sbjct:  188 FYWFDAYEDRIKQPGVVYLFGKVKIESAGKYVSCCVTIKNIDRNIFILPREKRIGADGSESENSVGFKDVYEEFNEKIASKNKIMKFVCRKVEKSYAFDIEDIPTSSEYLEVRYSVVWSQ---------------------------------TWLSL-------QWFPNC-LWFSM------------EPDQVIHNLSMKTLMNSRTHTQEVLAVSALVHQEVAVDKAAPKDKFQYRFCVLVSS----MMMHLHIFFTDFWHCIPQHLKIDVMASERALLAFVVAKIHKIDPDVLVGHDIFGFDLDILLHRISACKIPQWSRIGRLKRSI-MPKVRLSLGRGGHN----VDPTVTCGRLLCDVKISSRELIRSKSYDLSELSRVVLQTPRQELDQD----DIGNMYNTSQELLHLLELTTVDSLLTLRIMYELNVLPLAHQITTIAGNVLSRTLLGGRSKRNEFLLLHAFHEKGYICPDKSYGKKQVVR-EDDDDHVTTTKKGRRKPAYAGGLVLEPKKGFYDKFILLLDFNSLYPSIIQEYNICFTTIDR---KSAKDEEDDIVDLPDMD-----QDPGILPTEIRKLVERRRQVKGMMKTVSRDSDKYLQYDIRQKALKLTANSMYGCLGFSHSRFYAKPLAALVTSKGREILMKTKDLVQ------------QMHLDVIYGDTDSIMINT---NSTDLQEVKKVGNKVRHP---HATYLVLPVSYTLRFVNLLHILFSRYAAIMI--SENEDGTMNEVKEMKGLDIVRRDWCDLAKDAGNYVLSQILSAQ-SREAIVDNVHDFLITIGEDVKGGKVDLQKYVINKQLTKAPHDYPDKKSLPHVHVALWLMSKS---RKVGVGDTIPYVICDVSMHLPLVTCGALVHYLLRYLWRTCTLSLTLPVTHVYTISY--------ISDPIDGTDSARIAECLGLDPSGYRHAATRHDDEADALLGGQAQMTDEERFKDCVRLVLKCKQPGCDQQTTIE---ELCKDASARTPLLSALCPGCEKLYSPATVIN---HLTVIIRKHIKEYYAGWQRCEDPS--------CDHRTRQVPLMHHRGTPTCPNCHRAHMLPVYSDTALYNQLLFYGRLFDADRALKTLKDNGGKDFLLKSYLKENKIVKSFYTDVHTALQRIIEANAYSEVDLAKLFKTF 1240

HSP 2 Score: 54.299 bits (129), Expect = 4.116e-7
Identity = 30/76 (39.47%), Postives = 48/76 (63.16%), Query Frame = 2

Query:  140 LKQEIEVEDIYDVVNEETYEKLKEKRQLDNFI---EGDSEYMESGKEIFDES-DEEDIKIGPKRKKSMKNANLKNP 355
            + Q   V+D+Y VV+EE Y  +  +RQ ++++   +G   Y+E G+EIFD+  DEE+++ GPK K   K  N+K P
Sbjct:    5 IAQVGSVKDVYRVVDEEEYSDIVRQRQEEDWVVDDDGAGGYVEDGREIFDDDLDEEEVQKGPKHKP--KKQNVKKP 78

[Close]

BLAST of DNA polymerase vs. Ensembl Nematostella
Match: EDO49294 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A7RH52])

HSP 1 Score: 200.29 bits (508), Expect = 4.878e-52
Identity = 208/755 (27.55%), Postives = 333/755 (44.11%), Query Frame = 2

Query: 1706 VLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIER----MATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMD--LSHKSVAKPPGILPIEIRKLVEARNAVK-QLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRY-KGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQHNEADNTYSKQES-TDEANRFIDCKPL-----PIYCRKCQHKTSIDFKMELE----------KPWL-CGNCNVEL 3895
            VL    E  L       +   DPDII G+ ++ + L  LL R  AL++N +   GR+    +    T   + ++ +R    +  +GR+  D+        K RSY    +    L E+ K  V    + DL    + +   ++L    + ++++ + L+ +L  +   +E+  + G  +   LS G+  +    LL   ++   ++P   A           ++ E+          YAG  V+EP KG Y   I  +DF+SLYPSI++ +N+C+T++     +     DQ +          KSV K  G+LP  +  L+ AR   K  L    +  K+K+L  D RQ ALKI+ANS+YG  G    +    +++  VT  GR ++  TK+++E   AK +          +IYGDTDSVMV  G+  V +    M++G    E V+  + K I+L  + V    LL++KK+YA L     DK       K + KG++ VRRD C L   +    L  +L E  +P+        Y K +  D+   +I + + +ITK LT+  E Y+  Q    +   +R   AG + K     D V Y+I        A ++A  P  VL      E  + ID  YYL +QL   + R+ EPI  +  S  +  L     K  H        +T  K    T + +  I CK L        C+ C+ + S  F+ E+E          + W  C NC   L
Sbjct:  358 VLSFDKEADLFKAWSEFVQECDPDIITGYNIVNFDLPYLLNRATALHVNNFSLLGRIVADKSTVTSTTFQSKAYGKRENKVINISGRVQFDLLHVLLRDYKLRSYTLNAVSFHFLQEQ-KEDVQHNIISDLQNGNDQTR--RRLAIYCMKDAILPLRLLEKLMCVINYMEMARVTGVPMGYLLSRGQQIKVMSQLLRKTHQTDLVIPAHKA-----------EAGEE----------YAGATVIEPNKGYYNIPIATLDFSSLYPSIMMAHNLCYTSLLHPSQVKETPPDQYIKTPSGNFFVKKSVRK--GLLPEILEHLLTARKKAKADLKKETDPFKKKVL--DGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTAFGRMMIERTKELVE---AKYTVANGYKTDAKVIYGDTDSVMVRFGVETVAE---SMELGNEAAEYVSEHFVKPIKLEFEKVYFPYLLISKKRYAGLYFTKPDKHD-----KMDCKGIETVRRDNCPLVANLINACLKKLLIER-NPQGAV----EYTKQVISDLLCNRIDISQLVITKELTKTGEEYAGKQAHSELAERMRKRDAGSAPK---LGDRVPYVIIAGAKGAKAYEKAEDPIYVL------ENNVPIDTGYYLENQLSKPLLRIFEPI--LGESKASSAL----LKGEHTRTKTIVTSTVGKLSMFTKKRSTCIGCKALLDDDGSAVCKHCKSRESELFQKEIEHLRVLEERFARLWTQCQNCTGSL 1053

[Close]

BLAST of DNA polymerase vs. Ensembl Nematostella
Match: EDO27819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T875])

HSP 1 Score: 155.221 bits (391), Expect = 4.124e-42
Identity = 97/261 (37.16%), Postives = 153/261 (58.62%), Query Frame = 2

Query: 3011 IKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLG--LDPSKYHH-ANQHN-EADNTYSKQESTDEANRF 3781
            +K EVN+ Y+ ++++IDG+ + +LLL KKKYA++ +   +   G +   +E+KGLDIVRRDWC L+ + G  +L+ IL  + S E +  ++H++L +I +D++  K+ L K++I K LT+ P +Y + +  PHV VAL + S     ++    DT+ Y+IC+                +L   R  +  L ID  YYLA+Q+HPVV RL +PID  D++ +AE LG  L PS Y H A +H+ EAD    +     +  RF
Sbjct:    1 MKSEVNKLYRLLEIDIDGIFKSMLLLKKKKYAAIMI--SENEDGTMNEVKEMKGLDIVRRDWCDLAKDAGNYVLSQILSAQ-SREAIVDNVHDFLITIGEDVKGGKVDLQKYVINKQLTKAPHDYPDKKSLPHVHVALWLMSKS---RKVGVGDTIPYVICDVSMHLPLVTCGALVHYLLHEFRKSD-SLKIDTKYYLANQVHPVVARLCDPIDGTDSARIAECLGGILHPSGYRHAATRHDEEADALLGRHAQMTDEERF 254

[Close]

BLAST of DNA polymerase vs. Ensembl Nematostella
Match: EDO42056 (DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A7S2J9])

HSP 1 Score: 107.457 bits (267), Expect = 4.362e-24
Identity = 124/528 (23.48%), Postives = 211/528 (39.96%), Query Frame = 2

Query: 1724 ERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMAT----AGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQL--IDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTT-IDRCKYLSVGDTDQAMHILMDLSHKSVAKPP--------------------------GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQS-RFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMV-NTGIGNVYQYDTVMKIGQLIKEEVN-RRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWC 3199
            E+ L   LL      DPD+++G+ +     G L+QR    +++   K  R+  S +   +    +  W    A+    AGR++ +V    R  +    Y   ++   +L E+   F    P   L   ++    + +   +   +     N+ L+ +L  +    E+  + G L    +S G   R E ++L       YI     AA P      + Q N      S R P     LVLEP+   Y + +L++DF SLYPS+++ YN C++T + R   ++ G               S+++PP                          G+LP  +  ++  R  VK  +     +K      D RQ  LK+ AN  YG    + S R    ++A  +    RE L     ++ +  +K   +        ++YGDTDS+ V   G+      D   +IG  I E V  +  K ++L  + V    +L  KK+Y      + D+         + KG++ VRRD C
Sbjct:    6 EKDLFPALLGLFREWDPDVLIGYEVQMLSWGYLIQRALVFDLDLASKLARVSGSSSSSNMDSEKD-QWGAAHASEIKIAGRIVLNVWRLMRHEVTLNVYSFENVAFHVLHERIPLF----PYRSLSDWWDHKTDMHRWRTVQHYVTRCCGNVRLLEQLDFIGRTSELARLFGILFYSVISRGSQFRVESMMLRIAKPMNYI-----AASPS-----VQQRN------SMRAPEVIP-LVLEPESRFYHHPVLVLDFQSLYPSMMIAYNYCYSTCLGRVSSIAEGSH-------FKFGALSLSEPPSLLKQLERDIHISPNGVAFVKSNVRRGVLPRMLEDILNTRIMVKNSMKKWKDNKSTYRMLDARQLGLKLIANVTYGYTSANFSGRMPCVEIADSIVRKARETLERAIDLV-NTTSKWGAR--------VVYGDTDSLFVLLKGVSK----DEAFRIGHEITETVTAQNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETADQKEAVF----DAKGIETVRRDTC 487

[Close]

BLAST of DNA polymerase vs. Ensembl Medaka
Match: pola1 (DNA polymerase alpha 1, catalytic subunit [Source:NCBI gene;Acc:101165771])

HSP 1 Score: 809.29 bits (2089), Expect = 0.000e+0
Identity = 554/1524 (36.35%), Postives = 812/1524 (53.28%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEGD--SEYMESGKEIFDESDEEDI--------KIGPKRKKSMK---------------NANLKNPKKACLDFK--SIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSKIKPNEPKEMPQ-----KTVQEPIKFVKKQIV----FNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVV-----SAGFATDTKLEEHK------PL-------WETEEIEDESSNDKYDPFENIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKD-------------QAQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLN-FXXXXXXXXXXXXXXSPPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQ---GGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP---GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQHN---EADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELE----KPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL----------LTGKENLSYK----QKELLQMCSKYVERVLERSDYMNVDFKSLMAKFS 4291
            R RR++  +K+ +   L +LKKAK  G  +K ++E    +Y+ V+EE Y KL ++RQ D++I  D  + Y+E G+EIFD+  ++D+          G + KK++K               N+N+K P +  +D     +  D  + L S  P                  A L+ P       P ++ KK   K  +  P  ++   I+   PKE P      KTV+ P   ++          K S +  K     E N         D + LD++DFDEP ET P +     +    +  K+E  K      PL       W  EE   E+         ++D S L L+           YW DA+ D    PGVV+LFGK   +S K  V+ C+ V  +ER IY+LP++                M +VY E   +  K  +   ++K V K YAF+  DVP++ +YL +QY ++FP LP DL G TFS IFG NTS LE F+L  ++KGPCWL     +      S CK+    ++G     ++    PP +++S+++KTV N K++ NEIV++   +H   ++D+APP   +QN F +++ P D + PYD  + L  + G      V I + ER+L+   L K+H +DPD++VGH + G+ L +LLQR     +  W K GRL+R+  +PK+ G     + E+ AT GRL+CDVE+SA+ELI+C+SY   +L  ++L    K    +VP  ++  L++ S  +  L++LT  ++ + + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF++K YIVPDK +   + +QLE+    E    G    K+K  Y+GGLVL+PK G Y+ F+LL+DFNSLYPSII E+NICFTT+ R       ++ +            +  P    GILP EIRKLVE R  VKQL+   +++ +  +Q+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK +++        K+N    L++IYGDTDS+M+NT   N    + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L  V      G+  +KQELKGLDIVRRDWC L+ E G  ++  IL ++ S + +  +I  +L  + + + N  I L  + I KALT++P++Y + +  PHV VAL INS GG  ++ +A DT+ Y+IC DG++  A+QRAY+ +++      ++  LS+D  YYLA Q+HPVV R+ EPI+ ID   +A  LGLDPS +    QH    EAD          +  R+ DC+     C  C      D   E      +P L   C++       D  V+++ KL   I R I  YYS    C+           C    R+L +   +    CP C    ++P  S   L  QL +YRF+          LT +E L       QKE+ +   +  E+ L  S Y  V+   L   FS
Sbjct:   29 RSRREKR-EKVGRKSALEQLKKAKM-GEKIKYKVEEFSHVYEEVDEEQYSKLVQERQEDDWIIDDDGTGYVEDGREIFDDDLDDDVVEKRGKGGAKGAESKKTVKKAAVTKPNTIKSLFMNSNVKKPAEKDIDLSKDDLLGDILQDLHSEKP------------------AVLAPP-------PVITLKK---KKSLGSP--MNPFSIRHQMPKESPMTGLKAKTVRPPPAELRPPACPSPPLEKSSEKVEKPKEEEEEN---------DSLALDEVDFDEPMETEPEIKEETEAEAAPSVPKVEPKKEPLSPAPLPSRVGGHWGQEE---ETGASDVPAEVHVDSSQLPLVEGEDGEPAFRFYWLDAFEDPYNQPGVVYLFGKVWIQSAKSHVSCCVTVKNIERTIYLLPREYKTNPKTGEVSGEPVGMMDVYQEFSELSEKFKVMKFKSKKVEKNYAFEIPDVPNQCEYLQIQYSAEFPALPPDLKGATFSHIFGTNTSSLEHFLLSRKIKGPCWLDIKTPQMMHQPVSWCKVEVLALRGDTISLVKDLPPPPLTVMSISLKTVQNPKTHHNEIVSLAALLHYGFHMDKAPPQTPYQNYFCVISKPADCIFPYDFKEALRKKNG-----KVEIASTERTLLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLRRA-NMPKLGGRG--LFAEKNATCGRLVCDVEISAKELIRCKSYHLTELAAQVL----KVERVTVPQEEVKNLYSDSPHLLYLLELTWTDAKLILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFHDKNYIVPDKPSF--KKAQLEMGDGEEDVDAGKGKRKKKAAYSGGLVLDPKVGFYDQFVLLLDFNSLYPSIIQEFNICFTTVQR----EAQNSRRKREEDESEEIPEIPDPGLEMGILPKEIRKLVERRKQVKQLMKQQDINPDLYMQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKDMVQ--------KMN----LEVIYGDTDSIMINT---NSKSLEEVFKLGNKVKAEVNKLYKLLEIDIDGVFKSLLLLKKKKYAAL--VVEHHGDGRYSVKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQ-SRDIIVENIQKHLVEVGERVANGDIPLNLYEIHKALTKDPQDYPDKKSLPHVHVALWINSQGG--RRVKAGDTISYLICKDGSTLAASQRAYALEQL-----QKQEGLSVDTQYYLAQQIHPVVSRICEPIEGIDGVLIATWLGLDPSHFRSHQQHQREEEADGMLGAPVQLTDEERYRDCERFTFTCPSCGTDNIYDNVFEGAGNKVEPGLMRCCHIPCQSRPIDHPVHISNKLLLDIRRHIKKYYSGWLVCE--------DQACQNRTRRLPIAFSRHGPICPACSRATLRPEYSEKALYNQLCFYRFIFDWEHAFSKVLTQEERLLVNQMKMQKEVYRKLKEVPEKALAASGYSEVNLAKLFQAFS 1457

[Close]

BLAST of DNA polymerase vs. Ensembl Medaka
Match: pola1 (DNA polymerase alpha 1, catalytic subunit [Source:NCBI gene;Acc:101165771])

HSP 1 Score: 808.52 bits (2087), Expect = 0.000e+0
Identity = 554/1524 (36.35%), Postives = 812/1524 (53.28%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEGD--SEYMESGKEIFDESDEEDI--------KIGPKRKKSMK---------------NANLKNPKKACLDFK--SIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSKIKPNEPKEMPQ-----KTVQEPIKFVKKQIV----FNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVV-----SAGFATDTKLEEHK------PL-------WETEEIEDESSNDKYDPFENIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKD-------------QAQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLN-FXXXXXXXXXXXXXXSPPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQ---GGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP---GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQHN---EADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELE----KPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL----------LTGKENLSYK----QKELLQMCSKYVERVLERSDYMNVDFKSLMAKFS 4291
            R RR++  +K+ +   L +LKKAK  G  +K ++E    +Y+ V+EE Y KL ++RQ D++I  D  + Y+E G+EIFD+  ++D+          G + KK++K               N+N+K P +  +D     +  D  + L S  P                  A L+ P       P ++ KK   K  +  P  ++   I+   PKE P      KTV+ P   ++          K S +  K     E N         D + LD++DFDEP ET P +     +    +  K+E  K      PL       W  EE   E+         ++D S L L+           YW DA+ D    PGVV+LFGK   +S K  V+ C+ V  +ER IY+LP++                M +VY E   +  K  +   ++K V K YAF+  DVP++ +YL +QY ++FP LP DL G TFS IFG NTS LE F+L  ++KGPCWL     +      S CK+    ++G     ++    PP +++S+++KTV N K++ NEIV++   +H   ++D+APP   +QN F +++ P D + PYD  + L  + G      V I + ER+L+   L K+H +DPD++VGH + G+ L +LLQR     +  W K GRL+R+  +PK+ G     + E+ AT GRL+CDVE+SA+ELI+C+SY   +L  ++L    K    +VP  ++  L++ S  +  L++LT  ++ + + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF++K YIVPDK +   + +QLE+    E    G    K+K  Y+GGLVL+PK G Y+ F+LL+DFNSLYPSII E+NICFTT+ R       ++ +            +  P    GILP EIRKLVE R  VKQL+   +++ +  +Q+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK +++        K+N    L++IYGDTDS+M+NT   N    + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L  V      G+  +KQELKGLDIVRRDWC L+ E G  ++  IL ++ S + +  +I  +L  + + + N  I L  + I KALT++P++Y + +  PHV VAL INS GG  ++ +A DT+ Y+IC DG++  A+QRAY+ +++      ++  LS+D  YYLA Q+HPVV R+ EPI+ ID   +A  LGLDPS +    QH    EAD          +  R+ DC+     C  C      D   E      +P L   C++       D  V+++ KL   I R I  YYS    C+           C    R+L +   +    CP C    ++P  S   L  QL +YRF+          LT +E L       QKE+ +   +  E+ L  S Y  V+   L   FS
Sbjct:   25 RSRREKR-EKVGRKSALEQLKKAKM-GEKIKYKVEEFSHVYEEVDEEQYSKLVQERQEDDWIIDDDGTGYVEDGREIFDDDLDDDVVEKRGKGGAKGAESKKTVKKAAVTKPNTIKSLFMNSNVKKPAEKDIDLSKDDLLGDILQDLHSEKP------------------AVLAPP-------PVITLKK---KKSLGSP--MNPFSIRHQMPKESPMTGLKAKTVRPPPAELRPPACPSPPLEKSSEKVEKPKEEEEEN---------DSLALDEVDFDEPMETEPEIKEETEAEAAPSVPKVEPKKEPLSPAPLPSRVGGHWGQEE---ETGASDVPAEVHVDSSQLPLVEGEDGEPAFRFYWLDAFEDPYNQPGVVYLFGKVWIQSAKSHVSCCVTVKNIERTIYLLPREYKTNPKTGEVSGEPVGMMDVYQEFSELSEKFKVMKFKSKKVEKNYAFEIPDVPNQCEYLQIQYSAEFPALPPDLKGATFSHIFGTNTSSLEHFLLSRKIKGPCWLDIKTPQMMHQPVSWCKVEVLALRGDTISLVKDLPPPPLTVMSISLKTVQNPKTHHNEIVSLAALLHYGFHMDKAPPQTPYQNYFCVISKPADCIFPYDFKEALRKKNG-----KVEIASTERTLLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLRRA-NMPKLGGRG--LFAEKNATCGRLVCDVEISAKELIRCKSYHLTELAAQVL----KVERVTVPQEEVKNLYSDSPHLLYLLELTWTDAKLILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFHDKNYIVPDKPSF--KKAQLEMGDGEEDVDAGKGKRKKKAAYSGGLVLDPKVGFYDQFVLLLDFNSLYPSIIQEFNICFTTVQR----EAQNSRRKREEDESEEIPEIPDPGLEMGILPKEIRKLVERRKQVKQLMKQQDINPDLYMQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKDMVQ--------KMN----LEVIYGDTDSIMINT---NSKSLEEVFKLGNKVKAEVNKLYKLLEIDIDGVFKSLLLLKKKKYAAL--VVEHHGDGRYSVKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQ-SRDIIVENIQKHLVEVGERVANGDIPLNLYEIHKALTKDPQDYPDKKSLPHVHVALWINSQGG--RRVKAGDTISYLICKDGSTLAASQRAYALEQL-----QKQEGLSVDTQYYLAQQIHPVVSRICEPIEGIDGVLIATWLGLDPSHFRSHQQHQREEEADGMLGAPVQLTDEERYRDCERFTFTCPSCGTDNIYDNVFEGAGNKVEPGLMRCCHIPCQSRPIDHPVHISNKLLLDIRRHIKKYYSGWLVCE--------DQACQNRTRRLPIAFSRHGPICPACSRATLRPEYSEKALYNQLCFYRFIFDWEHAFSKVLTQEERLLVNQMKMQKEVYRKLKEVPEKALAASGYSEVNLAKLFQAFS 1453

[Close]

BLAST of DNA polymerase vs. Ensembl Medaka
Match: pola1 (DNA polymerase alpha 1, catalytic subunit [Source:NCBI gene;Acc:101165771])

HSP 1 Score: 793.882 bits (2049), Expect = 0.000e+0
Identity = 548/1524 (35.96%), Postives = 801/1524 (52.56%), Query Frame = 2

Query:   53 RPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIE-VEDIYDVVNEETYEKLKEKRQLDNFIEGD--SEYMESGKEIFDESDEEDI--------KIGPKRKKSMK---------------NANLKNPKKACLDFK--SIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSKIKPNEPKEMPQ-----KTVQEPIKFVKKQIV----FNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVV-----SAGFATDTKLEEHK------PL-------WETEEIEDESSNDKYDPFENIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKD-------------QAQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLN-FXXXXXXXXXXXXXXSPPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQ---GGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP---GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQHN---EADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELE----KPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL----------LTGKENLSYK----QKELLQMCSKYVERVLERSDYMNVDFKSLMAKFS 4291
            R RR++  +K+ +   L +LKKAK  G  +K ++E    +Y+ V+EE Y KL ++RQ D++I  D  + Y+E G+EIFD+  ++D+          G + KK++K               N+N+K P +  +D     +  D  + L S  P                  A L+ P       P ++ KK   K  +  P  ++   I+   PKE P      KTV+ P   ++          K S +  K     E N         D + LD++DFDEP ET P +     +    +  K+E  K      PL       W  EE   E+         ++D S L L+           YW DA+ D    PGVV+LFGK   +S K  V+ C+ V  +ER IY+LP++                M +VY E   +  K  +   ++K V K YAF+  DVP++ +YL +QY ++FP LP DL G TFS IFG NTS LE F+L  ++KGPCWL     +      S CK+    ++G     ++    PP +++S+++KTV N K++ NEIV++   +H   ++D+APP   +QN F +++ P D + PYD  + L  + G      V I + ER+L+   L K+H +DPD++VGH + G+ L +LLQR     +  W K GRL+R+  +PK+ G     + E+ AT GRL+CDVE+SA+ELI+C+SY   +L  ++L    K    +VP  ++  L++ S  +  L++LT  ++ + + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF++K YIVPDK +   + +QLE+    E    G    K+K  Y+GGLVL+PK G Y+ F+LL+DFNSLYPSII E+NICFTT+ R       ++ +            +  P    GILP EIRKLVE R  VKQL+   +++ +  +Q+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GRE+                        L++IYGDTDS+M+NT   N    + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L  V      G+  +KQELKGLDIVRRDWC L+ E G  ++  IL ++ S + +  +I  +L  + + + N  I L  + I KALT++P++Y + +  PHV VAL INS GG  ++ +A DT+ Y+IC DG++  A+QRAY+ +++      ++  LS+D  YYLA Q+HPVV R+ EPI+ ID   +A  LGLDPS +    QH    EAD          +  R+ DC+     C  C      D   E      +P L   C++       D  V+++ KL   I R I  YYS    C+           C    R+L +   +    CP C    ++P  S   L  QL +YRF+          LT +E L       QKE+ +   +  E+ L  S Y  V+   L   FS
Sbjct:   25 RSRREKR-EKVGRKSALEQLKKAKM-GEKIKYKVEEFSHVYEEVDEEQYSKLVQERQEDDWIIDDDGTGYVEDGREIFDDDLDDDVVEKRGKGGAKGAESKKTVKKAAVTKPNTIKSLFMNSNVKKPAEKDIDLSKDDLLGDILQDLHSEKP------------------AVLAPP-------PVITLKK---KKSLGSP--MNPFSIRHQMPKESPMTGLKAKTVRPPPAELRPPACPSPPLEKSSEKVEKPKEEEEEN---------DSLALDEVDFDEPMETEPEIKEETEAEAAPSVPKVEPKKEPLSPAPLPSRVGGHWGQEE---ETGASDVPAEVHVDSSQLPLVEGEDGEPAFRFYWLDAFEDPYNQPGVVYLFGKVWIQSAKSHVSCCVTVKNIERTIYLLPREYKTNPKTGEVSGEPVGMMDVYQEFSELSEKFKVMKFKSKKVEKNYAFEIPDVPNQCEYLQIQYSAEFPALPPDLKGATFSHIFGTNTSSLEHFLLSRKIKGPCWLDIKTPQMMHQPVSWCKVEVLALRGDTISLVKDLPPPPLTVMSISLKTVQNPKTHHNEIVSLAALLHYGFHMDKAPPQTPYQNYFCVISKPADCIFPYDFKEALRKKNG-----KVEIASTERTLLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLRRA-NMPKLGGRG--LFAEKNATCGRLVCDVEISAKELIRCKSYHLTELAAQVL----KVERVTVPQEEVKNLYSDSPHLLYLLELTWTDAKLILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFHDKNYIVPDKPSF--KKAQLEMGDGEEDVDAGKGKRKKKAAYSGGLVLDPKVGFYDQFVLLLDFNSLYPSIIQEFNICFTTVQR----EAQNSRRKREEDESEEIPEIPDPGLEMGILPKEIRKLVERRKQVKQLMKQQDINPDLYMQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREM-----------------------NLEVIYGDTDSIMINT---NSKSLEEVFKLGNKVKAEVNKLYKLLEIDIDGVFKSLLLLKKKKYAAL--VVEHHGDGRYSVKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQ-SRDIIVENIQKHLVEVGERVANGDIPLNLYEIHKALTKDPQDYPDKKSLPHVHVALWINSQGG--RRVKAGDTISYLICKDGSTLAASQRAYALEQL-----QKQEGLSVDTQYYLAQQIHPVVSRICEPIEGIDGVLIATWLGLDPSHFRSHQQHQREEEADGMLGAPVQLTDEERYRDCERFTFTCPSCGTDNIYDNVFEGAGNKVEPGLMRCCHIPCQSRPIDHPVHISNKLLLDIRRHIKKYYSGWLVCE--------DQACQNRTRRLPIAFSRHGPICPACSRATLRPEYSEKALYNQLCFYRFIFDWEHAFSKVLTQEERLLVNQMKMQKEVYRKLKEVPEKALAASGYSEVNLAKLFQAFS 1442

[Close]

BLAST of DNA polymerase vs. Ensembl Medaka
Match: pola1 (DNA polymerase alpha 1, catalytic subunit [Source:NCBI gene;Acc:101165771])

HSP 1 Score: 772.696 bits (1994), Expect = 0.000e+0
Identity = 481/1245 (38.63%), Postives = 702/1245 (56.39%), Query Frame = 2

Query:  749 DCIVLDDIDFDEPFETNPVV-----SAGFATDTKLEEHK------PLWETEEIEDESSNDKYDPFE-NIDKSSLKLI-----------YWFDAYHDK-KIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQAQ-------MTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLN-FXXXXXXXXXXXXXXSPPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNS-VLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP------GILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPIDMIDASTVAEHLGLDPSKYHHANQHN---EADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELE----KPWLCGNCNVELLYSHAD-AVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFA--CPRCESGIMKPLLSSSLLNRQLGYYRFL----------LTGKEN----LSY-KQKELLQMCSKYVERVLERSDYMNVDFKSLMAKFS 4291
            D + LD++DFDEP ET P +     +    +  K+E  K      PL      ++E +     P E ++D S L L+           YW DA+ D    PGVV+LFGK   +S K  V+ C+ V  +ER IY+LP++          M +VY E   +  K  +   ++K V K YAF+  DVP++ +YL +QY ++FP LP DL G TFS IFG NTS LE F+L  ++KGPCWL     +      S CK+    ++G     ++    PP +++S+++KTV N K++ NEIV++   +H   ++D+APP   +QN F   +   D++               N++N  V I + ER+L+   L K+H +DPD++VGH + G+ L +LLQR     +  W K GRL+R+  +PK+ G     + E+ AT GRL+CDVE+SA+ELI+C+SY   +L  ++L    K    +VP  ++  L++ S  +  L++LT  ++ + + +M EL VLPLAL+IT I GN++ RTL GG+SERNEYLLLHAF++K YIVPDK +   + +QLE+  + ++    +++K  Y+GGLVL+PK G Y+ F+LL+DFNSLYPSII E+NICFTT+ R          +A +       + + + P      GILP EIRKLVE R  VKQL+   +++ +  +Q+DIRQKALK+TANSMYGCLGFS SRF A  LAALVT  GREIL++TK +++        K+N    L++IYGDTDS+M+NT   N    + V K+G  +K EVN+ YK ++++IDGV + +LLL KKKYA+L  V      G+  +KQELKGLDIVRRDWC L+ E G  ++  IL ++ S + +  +I  +L  + + + N  I L  + I KALT++P++Y + +  PHV VAL INS GG  ++ +A DT+ Y+IC DG++  A+QRAY+ +++      ++  LS+D  YYLA Q+HPVV R+ EPI+ ID   +A  LGLDPS +    QH    EAD          +  R+ DC+     C  C      D   E      +P L   C++       D  V+++ KL   I R I  YYS    C+           C    R+L +   +    CP C    ++P  S   L  QL +YRF+          LT +E      SY K K LL     +V++ L  S Y  V+   L   FS
Sbjct:  266 DSLALDEVDFDEPMETEPEIKEETEAEAAPSVPKVEPKKEPLSPAPLVGGHWGQEEETGASDVPAEVHVDSSQLPLVEGEDGEPAFRFYWLDAFEDPYNQPGVVYLFGKVWIQSAKSHVSCCVTVKNIERTIYLLPREYVSATVFPVGMMDVYQEFSELSEKFKVMKFKSKKVEKNYAFEIPDVPNQCEYLQIQYSAEFPALPPDLKGATFSHIFGTNTSSLEHFLLSRKIKGPCWLDIKTPQMMHQPVSWCKVEVLALRGDTISLVKDLPPPPLTVMSISLKTVQNPKTHHNEIVSLAALLHYGFHMDKAPPQTPYQNYFCGESPVLDFLT-------------LNFRNGKVEIASTERTLLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLRRA-NMPKLGGRG--LFAEKNATCGRLVCDVEISAKELIRCKSYHLTELAAQVL----KVERVTVPQEEVKNLYSDSPHLLYLLELTWTDAKLILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFHDKNYIVPDKPSF--KKAQLEMVGTFKK----TRKKAAYSGGLVLDPKVGFYDQFVLLLDFNSLYPSIIQEFNICFTTVQR----------EAQNSRRKREVEEIPEIPDPGLEMGILPKEIRKLVERRKQVKQLMKQQDINPDLYMQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKDMVQ--------KMN----LEVIYGDTDSIMINT---NSKSLEEVFKLGNKVKAEVNKLYKLLEIDIDGVFKSLLLLKKKKYAAL--VVEHHGDGRYSVKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQ-SRDIIVENIQKHLVEVGERVANGDIPLNLYEIHKALTKDPQDYPDKKSLPHVHVALWINSQGG--RRVKAGDTISYLICKDGSTLAASQRAYALEQL-----QKQEGLSVDTQYYLAQQIHPVVSRICEPIEGIDGVLIATWLGLDPSHFRSHQQHQREEEADGMLGAPVQLTDEERYRDCERFTFTCPSCGTDNIYDNVFEGAGNKVEPGLMRCCHIPCQSRPIDHPVHISNKLLLDIRRHIKKYYSGWLVCE--------DQACQNRTRRLPIAFSRHGPICPACSRATLRPEYSEKALYNQLCFYRFIFDWEHAFSKVLTQEERRKPKFSYTKLKPLLS----FVKKALAASGYSEVNLAKLFQAFS 1437

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BLAST of DNA polymerase vs. Ensembl Medaka
Match: pold1 (DNA polymerase delta 1, catalytic subunit [Source:NCBI gene;Acc:101155199])

HSP 1 Score: 183.726 bits (465), Expect = 1.868e-46
Identity = 188/671 (28.02%), Postives = 314/671 (46.80%), Query Frame = 2

Query: 1700 NSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIER----MATAGRLLCDV-EVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPP------------GILPIEIRKLVEARNAVK-QLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYK-GIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCKISLGKFIITKALTRNPENYSNPQGQPHVQVA--LRINSAGGSIKQYRAKDTVEYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVVCRLIEPI 3649
            + +L    E+ L+      L  +DPDII G+ +  +    L+ R  AL +  +   GR++   ++ K +   +     R    +   GR+  D+ +V  R+  K RSY    +    L E+ +    S+ + DL     +    ++L    L ++ + + L+ +L  +   +E+  + G  +   LS G+  +    LL               A+ QN  + + ++  +GG+       Y G  V+EP+KG Y   I  +DF+SLYPSI++ +N+C+TT+     L  G  ++     + LS +   K P            G+LP  +  L+ AR   K +L    +  K+++L  D RQ ALKI+ANS+YG  G    +    +++  VT  GR+++  TK+++E     ISN    +    +IYGDTDSVMV  G+  V +    M+IG+   E V+  +   I+L  + V    LL+NKK+YA L   S   +  K+    + KG++ VRRD C L       ++   L++ L   D   ++ +  + ISD + N +I + + +ITK LTR  + Y+  Q   HV++A  +R   AG +       D V Y+I        A  ++  P  VL      E  + ID  YYL  QL   + R+ EPI
Sbjct:  372 SQILCFTQEKQLLQSWAEFLRTVDPDIITGYNIQNFDFPYLINRAAALKVTYFPYLGRVRNMKSVLKESNFQSKQMGRRENKTINMEGRVQFDLLQVLLRDY-KLRSYTLNAVSFHFLQEQKEDVQHSI-ISDLQN--GNEQTRRRLAVYCLKDAYLPLRLLQKLMCVINYMEMARVTGVPLSYLLSRGQQIKVVSQLLRQ-------------AMKQNLVMPVVKT--EGGE------DYTGATVIEPEKGYYSVPITTLDFSSLYPSIMMAHNLCYTTL-----LQKGSVER-----LQLSSEDFIKTPTGDQFVKSSVRKGLLPEILENLLSARKRAKAELKKETDPFKKQVL--DGRQLALKISANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIERTKQLVESKYT-ISNGYQADAK--VIYGDTDSVMVKLGVATVKE---AMEIGREAAEWVSSHFTPPIKLEFEKVYYPYLLINKKRYAGLYFSSSADTHDKM----DCKGIETVRRDNCPLV----ANLINTCLQKILIDRDPQGAVDHAKEVISDLLCN-RIDISQLVITKELTRTAQEYAGKQA--HVELAERMRKRDAGSAPN---LGDRVPYVIIKAAKGAAAYMKSEDPIYVL------ENTIPIDTQYYLEQQLSKPLLRIFEPI 979

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BLAST of DNA polymerase vs. Planmine SMEST
Match: SMESG000079687.1 (SMESG000079687.1)

HSP 1 Score: 2010.73 bits (5208), Expect = 0.000e+0
Identity = 1017/1063 (95.67%), Postives = 1030/1063 (96.90%), Query Frame = 2

Query:   29 MSEDDTYGRPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIEVEDIYDVVNEETYEKLKEKRQLDNFIEGDSEYMESGKEIFDESDEEDIKIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSKIKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVVSAGFATDTKLEEHKPLWETEEIEDESSNDKYDPFENIDKSSLKLIYWFDAYHDKKIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQAQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEV 3217
            MSE DTYGRPRRQ+NSKKIDKNDLLGKLKKAKQYGRNLKQEIEVEDIYDVVNEETYEKLK KRQLDNFIEGDS+YMESGKEIFDESDEEDIKIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPKSSISKKK ENN LDDLLAELS+PNREEIKAPFLSKKKEEFKF+IHQPKVISSS IKPNEPKE+PQKT QEPIKF            ++ K    ++NNETPEQHKIED IVLDDIDFDEPFETNPV S G ATDTKLEEHKPLWETEEIEDESSNDK DPFENIDKSSLKLIYWFDAYHDKKIPGVVFLFGKTRDEST KFVNVCIRV+GLERRIYVLPKDQAQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQF+DVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFEIKGIKGIKIEKEKSPPFSILSLNIKTVMN  SNVNEIVAIGGFIHNEIYLDRAPP+KMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLD DIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDR KYLS+GDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEV
Sbjct:    1 MSEHDTYGRPRRQKNSKKIDKNDLLGKLKKAKQYGRNLKQEIEVEDIYDVVNEETYEKLKAKRQLDNFIEGDSDYMESGKEIFDESDEEDIKIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPKSSISKKKFENNKLDDLLAELSSPNREEIKAPFLSKKKEEFKFNIHQPKVISSSTIKPNEPKEIPQKTAQEPIKF------------KRIKHRVQLKNNETPEQHKIEDNIVLDDIDFDEPFETNPVESTGLATDTKLEEHKPLWETEEIEDESSNDKCDPFENIDKSSLKLIYWFDAYHDKKIPGVVFLFGKTRDESTNKFVNVCIRVYGLERRIYVLPKDQAQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFVDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFEIKGIKGIKIEKEKSPPFSILSLNIKTVMNKNSNVNEIVAIGGFIHNEIYLDRAPPNKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDLDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRNKYLSIGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEV 1051

[Close]

BLAST of DNA polymerase vs. Planmine SMEST
Match: SMESG000079687.1 (SMESG000079687.1)

HSP 1 Score: 2006.88 bits (5198), Expect = 0.000e+0
Identity = 1017/1061 (95.85%), Postives = 1029/1061 (96.98%), Query Frame = 2

Query:   35 EDDTYGRPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIEVEDIYDVVNEETYEKLKEKRQLDNFIEGDSEYMESGKEIFDESDEEDIKIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPXXXXXXXXXEXXXXXXXXAELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSKIKPNEPKEMPQKTVQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDFDEPFETNPVVSAGFATDTKLEEHKPLWETEEIEDESSNDKYDPFENIDKSSLKLIYWFDAYHDKKIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYVLPKDQAQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFXXXXXXXXXXXXXXSPPFSILSLNIKTVMNNKSNVNEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEV 3217
            E DTYGRPRRQ+NSKKIDKNDLLGKLKKAKQYGRNLKQEIEVEDIYDVVNEETYEKLK KRQLDNFIEGDS+YMESGKEIFDESDEEDIKIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPKSSISKKK ENN LDDLLAELS+PNREEIKAPFLSKKKEEFKF+IHQPKVISSS IKPNEPKE+PQKT QEPIKF  K+I          K    ++NNETPEQHKIED IVLDDIDFDEPFETNPV S G ATDTKLEEHKPLWETEEIEDESSNDK DPFENIDKSSLKLIYWFDAYHDKKIPGVVFLFGKTRDEST KFVNVCIRV+GLERRIYVLPKDQAQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQF+DVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFEIKGIKGIKIEKEKSPPFSILSLNIKTVMN  SNVNEIVAIGGFIHNEIYLDRAPP+KMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLD DIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDR KYLS+GDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEV
Sbjct:  321 ETDTYGRPRRQKNSKKIDKNDLLGKLKKAKQYGRNLKQEIEVEDIYDVVNEETYEKLKAKRQLDNFIEGDSDYMESGKEIFDESDEEDIKIGPKRKKSMKNANLKNPKKACLDFKSIHSDSQKSLFSMLPKSSISKKKFENNKLDDLLAELSSPNREEIKAPFLSKKKEEFKFNIHQPKVISSSTIKPNEPKEIPQKTAQEPIKF--KRI----------KHRVQLKNNETPEQHKIEDNIVLDDIDFDEPFETNPVESTGLATDTKLEEHKPLWETEEIEDESSNDKCDPFENIDKSSLKLIYWFDAYHDKKIPGVVFLFGKTRDESTNKFVNVCIRVYGLERRIYVLPKDQAQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFVDVPDETDYLMVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSGLESSSNQFSTCKLNFEIKGIKGIKIEKEKSPPFSILSLNIKTVMNKNSNVNEIVAIGGFIHNEIYLDRAPPNKMFQNNFIILTHPKDYVMPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDLDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRNKYLSIGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGCAKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVNRRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLDIVRRDWCKLSIEV 1369

[Close]

BLAST of DNA polymerase vs. Planmine SMEST
Match: SMESG000044739.1 (SMESG000044739.1)

HSP 1 Score: 777.319 bits (2006), Expect = 0.000e+0
Identity = 376/385 (97.66%), Postives = 379/385 (98.44%), Query Frame = 2

Query: 1646 MPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQA 2800
            MPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGH+NTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFK FVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQ+LPLALEITAICGNLICRTL GGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQ GKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDR KYLS+GDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARN VKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQ 
Sbjct:    1 MPYDLNQKLASEWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQRCQALNINTWYKFGRLKRSIALPKITGHNNTSWIERMATAGRLLCDVEVSARELIKCRSYEQRDLIQEMLPEKFKDFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQILPLALEITAICGNLICRTLFGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQSGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRNKYLSIGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNVVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQV 385

[Close]

BLAST of DNA polymerase vs. Planmine SMEST
Match: SMESG000044721.1 (SMESG000044721.1)

HSP 1 Score: 493.812 bits (1270), Expect = 5.906e-164
Identity = 239/255 (93.73%), Postives = 245/255 (96.08%), Query Frame = 2

Query: 2033 MLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLLLHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLEPKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHILMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIRQKALKITANSMYGCLGFSQSRFQ 2797
            MLPEKFK FVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQ+LPLALEITAICGNLICRTL GGKSERNEYLLLH+FNEKQYIVPDKAAALPQNSQLEIDQSNEQ GKFSKRKPTYA GLVLEPKKGLYEN ILLMDFNSLYPSIILEYNICFTTIDR  YLSV DTDQAMHIL+DLSHKSVA+PPGILP+EIRKLVEARN VKQLLNNPNLSK+KLLQHDIRQKALKIT NSMYGCLGFSQSRFQ
Sbjct:    1 MLPEKFKDFVSSVPVGDLCTLFNSSAGIKQLIDLTLDESLVNICLMHELQILPLALEITAICGNLICRTLFGGKSERNEYLLLHSFNEKQYIVPDKAAALPQNSQLEIDQSNEQSGKFSKRKPTYASGLVLEPKKGLYENLILLMDFNSLYPSIILEYNICFTTIDRNTYLSVSDTDQAMHILIDLSHKSVAEPPGILPMEIRKLVEARNVVKQLLNNPNLSKKKLLQHDIRQKALKITTNSMYGCLGFSQSRFQ 255

HSP 2 Score: 51.9878 bits (123), Expect = 1.314e-6
Identity = 23/25 (92.00%), Postives = 23/25 (92.00%), Query Frame = 3

Query: 3561 EPKNENYRSIIITIWHINSTQWFAD 3635
            EPKNENY SIIITIWHINSTQ FAD
Sbjct:  256 EPKNENYVSIIITIWHINSTQRFAD 280

[Close]

BLAST of DNA polymerase vs. Planmine SMEST
Match: SMESG000079942.1 (SMESG000079942.1)

HSP 1 Score: 452.595 bits (1163), Expect = 2.408e-149
Identity = 214/219 (97.72%), Postives = 217/219 (99.09%), Query Frame = 2

Query: 3653 MIDASTVAEHLGLDPSKYHHANQHNEADNTYSKQESTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELEKPWLCGNCNVELLYSHADAVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLLTGKENLSYKQKELLQMCSKYVERVLERSDYMNVDFKSLMAKFSRQIKIV 4309
            MIDASTVAEHLGLDPSKYHHANQHNEADNT+SKQ+STDEANRFIDCKPLPIYCRKCQHKTSIDFKMELEKPWLCGNC+ ELLYSHADAVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLLTGKENLSYK KELLQMCSKYVERVLERSDYMNVDFKSLMAKFSRQIKIV
Sbjct:    1 MIDASTVAEHLGLDPSKYHHANQHNEADNTFSKQDSTDEANRFIDCKPLPIYCRKCQHKTSIDFKMELEKPWLCGNCSGELLYSHADAVNVNKKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFACPRCESGIMKPLLSSSLLNRQLGYYRFLLTGKENLSYKHKELLQMCSKYVERVLERSDYMNVDFKSLMAKFSRQIKIV 219

The following BLAST results are available for this feature:

BLAST of DNA polymerase vs. Ensembl Human
BLAST of DNA polymerase vs. Ensembl Celegans
BLAST of DNA polymerase vs. Ensembl Fly
BLAST of DNA polymerase vs. Ensembl Zebrafish
BLAST of DNA polymerase vs. Ensembl Xenopus
BLAST of DNA polymerase vs. Ensembl Mouse
BLAST of DNA polymerase vs. UniProt/SwissProt
BLAST of DNA polymerase vs. TrEMBL
BLAST of DNA polymerase vs. Ensembl Cavefish
BLAST of DNA polymerase vs. Ensembl Sea Lamprey
BLAST of DNA polymerase vs. Ensembl Yeast
BLAST of DNA polymerase vs. Ensembl Nematostella
BLAST of DNA polymerase vs. Ensembl Medaka
BLAST of DNA polymerase vs. Planmine SMEST

BLAST of DNA polymerase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
POLA1	0.000e+0	36.90	DNA polymerase alpha 1, catalytic subunit [Source:...	[more]
POLA1	0.000e+0	36.90	DNA polymerase alpha 1, catalytic subunit [Source:...	[more]
POLA1	0.000e+0	36.90	DNA polymerase alpha 1, catalytic subunit [Source:...	[more]
POLD1	1.964e-47	28.38	DNA polymerase delta 1, catalytic subunit [Source:...	[more]
POLD1	1.964e-47	28.38	DNA polymerase delta 1, catalytic subunit [Source:...	[more]

BLAST of DNA polymerase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pola-1	1.019e-172	34.45	DNA polymerase [Source:UniProtKB/TrEMBL;Acc:C7IVS...	[more]
pola-1	7.866e-172	34.86	DNA polymerase [Source:UniProtKB/TrEMBL;Acc:C7IVS...	[more]
F10C2.4	9.301e-47	27.34	DNA polymerase delta catalytic subunit [Source:Un...	[more]
rev-3	1.663e-21	23.99	DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A0A0K...	[more]
rev-3	5.404e-21	23.99	DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A0A0K...	[more]

BLAST of DNA polymerase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
DNApol-alpha180	0.000e+0	37.64	gene:FBgn0259113 transcript:FBtr0084115	[more]
DNApol-delta	4.079e-46	26.93	gene:FBgn0263600 transcript:FBtr0075522	[more]
DNApol-zeta	2.257e-19	26.65	gene:FBgn0002891 transcript:FBtr0088831	[more]

BLAST of DNA polymerase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pola1	0.000e+0	37.18	polymerase (DNA directed), alpha 1 [Source:ZFIN;Ac...	[more]
pola1	0.000e+0	37.33	polymerase (DNA directed), alpha 1 [Source:ZFIN;Ac...	[more]
pola1	1.819e-86	35.84	polymerase (DNA directed), alpha 1 [Source:ZFIN;Ac...	[more]
pold1	1.014e-46	28.12	polymerase (DNA directed), delta 1, catalytic subu...	[more]
rev3l	5.444e-23	21.98	REV3 like, DNA directed polymerase zeta catalytic ...	[more]

BLAST of DNA polymerase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
POLA1	0.000e+0	36.07	polymerase (DNA directed), alpha 1, catalytic subu...	[more]
POLA1	0.000e+0	36.25	polymerase (DNA directed), alpha 1, catalytic subu...	[more]
POLA1	0.000e+0	38.99	polymerase (DNA directed), alpha 1, catalytic subu...	[more]
POLA1	9.016e-6	38.76	polymerase (DNA directed), alpha 1, catalytic subu...	[more]
POLA1	0.000e+0	38.76	polymerase (DNA directed), alpha 1, catalytic subu...	[more]

BLAST of DNA polymerase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pola1	0.000e+0	36.39	polymerase (DNA directed), alpha 1 [Source:MGI Sym...	[more]
Pold1	3.271e-44	27.55	polymerase (DNA directed), delta 1, catalytic subu...	[more]
Pold1	8.981e-38	27.15	polymerase (DNA directed), delta 1, catalytic subu...	[more]
Rev3l	6.714e-28	22.29	REV3 like, DNA directed polymerase zeta catalytic ...	[more]
Rev3l	6.714e-28	22.29	REV3 like, DNA directed polymerase zeta catalytic ...	[more]

BLAST of DNA polymerase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9DE46\|DPOLA_XENLA	0.000e+0	36.66	DNA polymerase alpha catalytic subunit OS=Xenopus ...	[more]
sp\|P09884\|DPOLA_HUMAN	0.000e+0	36.90	DNA polymerase alpha catalytic subunit OS=Homo sap...	[more]
sp\|P33609\|DPOLA_MOUSE	0.000e+0	36.39	DNA polymerase alpha catalytic subunit OS=Mus musc...	[more]
sp\|O89042\|DPOLA_RAT	0.000e+0	36.70	DNA polymerase alpha catalytic subunit (Fragment) ...	[more]
sp\|P26019\|DPOLA_DROME	0.000e+0	37.64	DNA polymerase alpha catalytic subunit OS=Drosophi...	[more]

BLAST of DNA polymerase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
V4BGE0	0.000e+0	39.02	DNA polymerase (Fragment) OS=Lottia gigantea OX=22...	[more]
E7FB68	0.000e+0	37.18	DNA polymerase OS=Danio rerio OX=7955 GN=pola1 PE=...	[more]
E9QIM3	0.000e+0	37.33	DNA polymerase OS=Danio rerio OX=7955 GN=pola1 PE=...	[more]
B1WBE2	0.000e+0	36.73	DNA polymerase OS=Xenopus laevis OX=8355 GN=LOC398...	[more]
B7ZRF3	0.000e+0	36.66	DNA polymerase OS=Xenopus laevis OX=8355 GN=LOC398...	[more]

BLAST of DNA polymerase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000007988.2	0.000e+0	35.95	pep primary_assembly:Astyanax_mexicanus-2.0:3:1893...	[more]
pold1	9.743e-48	27.79	DNA polymerase delta 1, catalytic subunit [Source:...	[more]
pold1	1.266e-47	27.79	DNA polymerase delta 1, catalytic subunit [Source:...	[more]
pold1	1.633e-33	31.34	DNA polymerase delta 1, catalytic subunit [Source:...	[more]
rev3l	1.076e-23	22.21	REV3 like, DNA directed polymerase zeta catalytic ...	[more]

BLAST of DNA polymerase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
pold1	3.165e-42	27.34	polymerase (DNA directed), delta 1, catalytic subu...	[more]
ENSPMAT00000006446.1	6.870e-13	24.56	pep scaffold:Pmarinus_7.0:GL477096:156518:193524:1...	[more]
ENSPMAT00000009864.1	6.065e-9	22.64	pep scaffold:Pmarinus_7.0:GL480102:12343:24944:1 g...	[more]

BLAST of DNA polymerase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
POL1	5.648e-145	31.62	Catalytic subunit of the DNA polymerase I alpha-pr...	[more]
POL3	1.545e-51	29.50	Catalytic subunit of DNA polymerase delta; require...	[more]
REV3	2.330e-28	23.34	Catalytic subunit of DNA polymerase zeta; involved...	[more]

BLAST of DNA polymerase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO39342	4.116e-7	35.26	DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A7SAB...	[more]
EDO49294	4.878e-52	27.55	DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A7RH5...	[more]
EDO27819	4.124e-42	37.16	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42056	4.362e-24	23.48	DNA polymerase [Source:UniProtKB/TrEMBL;Acc:A7S2J...	[more]

BLAST of DNA polymerase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pola1	0.000e+0	36.35	DNA polymerase alpha 1, catalytic subunit [Source:...	[more]
pola1	0.000e+0	36.35	DNA polymerase alpha 1, catalytic subunit [Source:...	[more]
pola1	0.000e+0	35.96	DNA polymerase alpha 1, catalytic subunit [Source:...	[more]
pola1	0.000e+0	38.63	DNA polymerase alpha 1, catalytic subunit [Source:...	[more]
pold1	1.868e-46	28.02	DNA polymerase delta 1, catalytic subunit [Source:...	[more]

BLAST of DNA polymerase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000079687.1	0.000e+0	95.67	SMESG000079687.1	[more]
SMESG000079687.1	0.000e+0	95.85	SMESG000079687.1	[more]
SMESG000044739.1	0.000e+0	97.66	SMESG000044739.1	[more]
SMESG000044721.1	5.906e-164	93.73	SMESG000044721.1	[more]
SMESG000079942.1	2.408e-149	97.72	SMESG000079942.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30004136 ID=SMED30004136|Name=DNA polymerase|organism=Schmidtea mediterranea sexual|type=transcript|length=4341bp
TTTAATTACAAAGATTTATTAGTTTGAAATGTCTGAAGACGATACTTATG
GAAGACCTAGGCGTCAGAGAAATTCAAAGAAAATTGATAAAAATGATTTG
CTTGGTAAATTAAAGAAGGCTAAGCAATATGGACGAAATCTGAAACAAGA
AATTGAAGTTGAAGATATTTATGATGTGGTTAATGAAGAAACTTATGAAA
AATTAAAAGAGAAGAGACAGTTGGATAATTTTATAGAAGGTGATTCAGAG
TATATGGAAAGTGGTAAAGAAATTTTCGATGAATCAGACGAGGAAGATAT
TAAAATTGGACCGAAACGCAAAAAATCAATGAAAAATGCTAATTTAAAAA
ATCCCAAAAAAGCTTGTTTAGATTTCAAAAGCATTCATAGTGATTCACAA
AAGAGTCTTTTTAGTATGTTACCCAAATCAAGTATTTCAAAAAAGAAAAT
TGAAAACAACAACCTAGATGATCTGCTAGCTGAGTTATCTACACCAAATC
GGGAAGAAATAAAGGCGCCATTTTTGTCAAAAAAGAAAGAAGAATTTAAG
TTTGACATACATCAACCGAAAGTCATAAGTTCATCGAAAATTAAACCAAA
TGAACCGAAAGAGATGCCTCAAAAAACTGTACAAGAGCCAATTAAATTTG
TGAAGAAACAAATAGTTTTTAATAAAGGATCTTCAGAAAAAAATAAATCA
CCGAGTACAATTGAAAATAATGAAACACCAGAACAACATAAAATTGAAGA
TTGTATTGTTCTGGATGATATAGATTTCGATGAGCCATTTGAGACAAATC
CAGTTGTATCAGCTGGATTTGCAACCGACACGAAATTGGAGGAACATAAA
CCTCTATGGGAAACTGAAGAGATAGAAGATGAAAGTTCAAATGATAAATA
TGATCCATTCGAAAATATAGATAAATCCTCATTGAAATTAATTTACTGGT
TCGATGCATATCACGACAAAAAGATTCCAGGAGTTGTATTTCTATTTGGG
AAAACCCGTGATGAATCCACAAAGAAATTTGTCAATGTCTGCATTAGGGT
TCACGGACTGGAAAGGAGGATTTATGTTCTGCCAAAGGACCAAGCCCAAA
TGACAGAGGTGTACAGTGAAGTGAAATCAATATTGGCCAAGCATGGCATT
GAGAGCTTACGCACGAAACCTGTAACTAAGAAATATGCGTTCCAATTTAT
TGACGTTCCCGATGAAACCGACTATTTAATGGTGCAATACGATTCTAAAT
TCCCTGAATTGCCCAGTGATTTAAGCGGGAAAACCTTTTCCCGAATATTT
GGTGCCAACACATCATGCTTAGAAATGTTTATTTTGGATCTGCGGCTAAA
AGGACCTTGTTGGTTAAGTTTCAGTGGATTAGAATCCTCAAGCAATCAAT
TTAGTACTTGTAAATTGAATTTCGAAATTAAAGGAATCAAAGGCATAAAG
ATTGAAAAAGAAAAAAGTCCACCATTTTCTATTCTGTCCTTAAATATAAA
AACTGTAATGAATAACAAGTCTAATGTCAATGAAATCGTTGCAATTGGTG
GATTTATTCACAATGAAATATATTTAGACAGAGCCCCTCCTAGCAAAATG
TTTCAGAATAACTTTATCATATTAACTCATCCAAAAGATTATGTCATGCC
GTATGATCTCAACCAAAAATTGGCATCAGAATGGGGCGCAAATTATAAAA
ATTCCGTACTAATTGAAGCCAATGAAAGGTCTCTCATCAGCTGCTTGCTC
AATAAACTGCATCACCTTGATCCCGATATCATCGTTGGCCATGCACTGAT
TGGCTACCAACTGGGAATTCTCCTCCAGAGATGTCAGGCACTGAATATAA
ACACCTGGTATAAATTCGGGCGCCTGAAGAGAAGCATTGCCCTGCCAAAG
ATCACCGGGCACAGCAACACATCGTGGATCGAAAGGATGGCAACAGCCGG
CCGGCTTCTGTGCGACGTAGAAGTCAGTGCTCGAGAACTGATTAAATGCC
GAAGCTATGAACAGCGTGATCTGATCCAGGAAATGCTGCCGGAGAAATTC
AAGGCCTTCGTAAGCAGTGTGCCTGTCGGTGATTTGTGCACCTTATTCAA
CAGTTCCGCCGGCATCAAACAATTAATCGATCTGACCCTTGACGAGTCGC
TGGTCAATATTTGCCTGATGCACGAACTGCAAGTCCTTCCTCTGGCATTG
GAAATAACAGCGATATGTGGAAATCTGATCTGTCGGACGTTATCTGGCGG
TAAATCCGAGCGCAATGAATATCTGCTGCTTCATGCATTCAATGAAAAGC
AATATATAGTGCCAGATAAAGCCGCCGCGTTGCCACAAAATAGCCAGCTA
GAAATTGACCAATCAAATGAGCAGGGCGGGAAATTCTCCAAGCGCAAGCC
AACTTATGCCGGCGGGCTTGTATTGGAACCGAAAAAGGGATTATATGAGA
ATTTCATTCTACTGATGGATTTCAATTCACTTTATCCGTCGATAATTCTG
GAATATAATATCTGCTTCACGACAATCGATCGCTGCAAATACCTCAGTGT
TGGCGACACTGATCAGGCAATGCATATACTGATGGATTTATCGCACAAAT
CGGTTGCCAAGCCGCCGGGAATATTACCAATAGAAATTCGGAAATTAGTA
GAGGCCAGAAACGCGGTGAAGCAACTTCTCAATAATCCCAATCTTTCGAA
GGAAAAGCTCCTCCAGCATGATATAAGGCAGAAAGCTCTCAAGATTACAG
CCAATAGTATGTATGGATGTTTGGGATTCAGCCAATCACGATTTCAGGCT
ACACAATTAGCAGCATTGGTTACATTTCATGGCAGAGAAATATTGATCAA
TACCAAAAAAATAATCGAAGACGGATGTGCAAAAATTTCCAATAAGATCA
ATTTGAATGTGGCGTTGGATATAATTTACGGTGACACCGATTCAGTGATG
GTGAACACCGGCATTGGGAATGTCTATCAGTATGATACGGTAATGAAAAT
TGGGCAGCTTATCAAGGAGGAAGTCAACCGACGATACAAAGGCATCCAAT
TGAACATTGACGGTGTCATGAGAAGAATATTACTGTTGAACAAAAAGAAA
TATGCGTCGTTAAATGTGGTTTCAAGGGATAAAAGCTCAGGAAAATTGAT
TCTTAAACAAGAACTAAAAGGCTTGGATATAGTTCGAAGAGATTGGTGTA
AACTGTCCATCGAAGTTGGTAAGCGCATATTGACAATGATTTTGGAAGAG
GAATTGTCGCCGGAGGATTTAGCATTTTCCATTCACAATTACCTTAAATC
AATTAGTGATGATATGAGAAACTGTAAAATCTCGTTGGGGAAGTTTATTA
TTACAAAGGCACTGACAAGGAATCCGGAAAATTATTCCAATCCCCAAGGC
CAACCGCATGTGCAAGTTGCATTGAGAATTAACAGTGCCGGCGGGTCTAT
CAAGCAGTACCGAGCAAAGGATACAGTGGAATACATTATTTGCAATGATG
GAACCTCAGAAACCGCAACTCAAAGAGCATATAGCCCAAAGGAAGTATTA
TCTTCAAGCCGAACCGAAGAACGAAAATTATCGATCGATTATAATTACTA
TCTGGCACATCAACTCCACCCAGTGGTTTGCAGATTAATTGAACCTATTG
ATATGATAGATGCATCAACGGTGGCAGAGCATTTAGGCCTTGATCCATCA
AAGTACCACCACGCTAACCAACATAATGAGGCAGATAATACCTATTCTAA
ACAAGAATCCACCGATGAAGCAAACCGATTTATTGATTGCAAACCTCTTC
CTATTTACTGCCGAAAGTGCCAACATAAAACGAGCATCGATTTTAAAATG
GAACTAGAGAAGCCTTGGTTATGTGGCAATTGCAATGTCGAGCTGTTATA
TTCACACGCTGATGCAGTTAATGTCAATAAGAAACTCAAGGAAATCATAG
ATCGAATAATTCACATATATTACTCGTGCATTTCCACGTGTCAATGCGGG
TATATCTGTCGGGGAATGGTCAATATATGCAATGAGGAAGCTAGGAAGTT
ATTAATGACAACCGGTCAATTTGCTTGTCCAAGATGTGAAAGCGGGATTA
TGAAGCCTCTACTCAGTAGTTCTTTACTTAATCGACAACTCGGTTATTAT
CGATTCTTACTTACTGGCAAAGAAAACCTATCGTACAAACAGAAAGAATT
ATTACAAATGTGCAGCAAATATGTGGAGCGAGTCCTGGAACGTTCCGATT
ACATGAATGTGGATTTCAAAAGTTTAATGGCGAAATTCTCACGACAGATT
AAAATTGTTTAATTTCCTATAGATTTTATGTTTTATAAATA

protein sequence of SMED30004136-orf-1

>SMED30004136-orf-1 ID=SMED30004136-orf-1|Name=SMED30004136-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1428bp
MSEDDTYGRPRRQRNSKKIDKNDLLGKLKKAKQYGRNLKQEIEVEDIYDV
VNEETYEKLKEKRQLDNFIEGDSEYMESGKEIFDESDEEDIKIGPKRKKS
MKNANLKNPKKACLDFKSIHSDSQKSLFSMLPKSSISKKKIENNNLDDLL
AELSTPNREEIKAPFLSKKKEEFKFDIHQPKVISSSKIKPNEPKEMPQKT
VQEPIKFVKKQIVFNKGSSEKNKSPSTIENNETPEQHKIEDCIVLDDIDF
DEPFETNPVVSAGFATDTKLEEHKPLWETEEIEDESSNDKYDPFENIDKS
SLKLIYWFDAYHDKKIPGVVFLFGKTRDESTKKFVNVCIRVHGLERRIYV
LPKDQAQMTEVYSEVKSILAKHGIESLRTKPVTKKYAFQFIDVPDETDYL
MVQYDSKFPELPSDLSGKTFSRIFGANTSCLEMFILDLRLKGPCWLSFSG
LESSSNQFSTCKLNFEIKGIKGIKIEKEKSPPFSILSLNIKTVMNNKSNV
NEIVAIGGFIHNEIYLDRAPPSKMFQNNFIILTHPKDYVMPYDLNQKLAS
EWGANYKNSVLIEANERSLISCLLNKLHHLDPDIIVGHALIGYQLGILLQ
RCQALNINTWYKFGRLKRSIALPKITGHSNTSWIERMATAGRLLCDVEVS
ARELIKCRSYEQRDLIQEMLPEKFKAFVSSVPVGDLCTLFNSSAGIKQLI
DLTLDESLVNICLMHELQVLPLALEITAICGNLICRTLSGGKSERNEYLL
LHAFNEKQYIVPDKAAALPQNSQLEIDQSNEQGGKFSKRKPTYAGGLVLE
PKKGLYENFILLMDFNSLYPSIILEYNICFTTIDRCKYLSVGDTDQAMHI
LMDLSHKSVAKPPGILPIEIRKLVEARNAVKQLLNNPNLSKEKLLQHDIR
QKALKITANSMYGCLGFSQSRFQATQLAALVTFHGREILINTKKIIEDGC
AKISNKINLNVALDIIYGDTDSVMVNTGIGNVYQYDTVMKIGQLIKEEVN
RRYKGIQLNIDGVMRRILLLNKKKYASLNVVSRDKSSGKLILKQELKGLD
IVRRDWCKLSIEVGKRILTMILEEELSPEDLAFSIHNYLKSISDDMRNCK
ISLGKFIITKALTRNPENYSNPQGQPHVQVALRINSAGGSIKQYRAKDTV
EYIICNDGTSETATQRAYSPKEVLSSSRTEERKLSIDYNYYLAHQLHPVV
CRLIEPIDMIDASTVAEHLGLDPSKYHHANQHNEADNTYSKQESTDEANR
FIDCKPLPIYCRKCQHKTSIDFKMELEKPWLCGNCNVELLYSHADAVNVN
KKLKEIIDRIIHIYYSCISTCQCGYICRGMVNICNEEARKLLMTTGQFAC
PRCESGIMKPLLSSSLLNRQLGYYRFLLTGKENLSYKQKELLQMCSKYVE
RVLERSDYMNVDFKSLMAKFSRQIKIV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

Vocabulary: **molecular function**
Term	Definition
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding
GO:0004197	cysteine-type endopeptidase activity
GO:0003676	nucleic acid binding
GO:0003887	DNA-directed DNA polymerase activity
GO:0000166	nucleotide binding
GO:0001882	nucleoside binding
GO:0008408	3'-5' exonuclease activity
GO:0003677	DNA binding
GO:0016740	transferase activity
GO:0016779	nucleotidyltransferase activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000014	zeta neoblast
PLANA:0000070	intestinal phagocyte
PLANA:0000074	oocyte
PLANA:0000099	neuron
PLANA:0000231	vitelline gland
PLANA:0000429	neoblast
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR008741	AV_PCPalpha
IPR006172	DNA-dir_DNA_pol_B
IPR015088	Znf_DNA-dir_DNA_pol_B_alpha
IPR024647	DNA_pol_a_cat_su_N
IPR023211	DNA_pol_palm_dom_sf
IPR006133	DNA-dir_DNA_pol_B_exonuc
IPR006134	DNA-dir_DNA_pol_B_multi_dom
IPR012337	RNaseH-like_sf
IPR017964	DNA-dir_DNA_pol_B_CS