NIPSNAP domain-containing protein

Overview


Name	NIPSNAP domain-containing protein
Smed ID	SMED30004082
Length (bp)	950

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of NIPSNAP domain-containing protein (SMED30004082) t-SNE clustered cells

Violin plots show distribution of expression levels for NIPSNAP domain-containing protein (SMED30004082) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of NIPSNAP domain-containing protein (SMED30004082) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for NIPSNAP domain-containing protein (SMED30004082) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30004082

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30004082	h1SMcG0020245	Contig44461	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30004082	h1SMcG0020245	Contig44461	newmark_ests	PMID:29674431 Fincher et al., 2018
gut	SMED30004082	h1SMcG0020245	dd_Smed_v4_2078_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30004082	h1SMcG0020245	dd_Smed_v4_2078_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30004082	h1SMcG0020245	dd_Smed_v4_2078_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30004082	h1SMcG0020245	dd_Smed_v4_2078_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30004082	h1SMcG0020245	Contig47137	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30004082	h1SMcG0020245	Contig47137	newmark_ests	PMID:29674431 Fincher et al., 2018
head region	SMED30004082	h1SMcG0020245	OX_Smed_1.0.23423	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of NIPSNAP domain-containing protein vs. Ensembl Human
Match: NIPSNAP1 (nipsnap homolog 1 [Source:HGNC Symbol;Acc:HGNC:7827])

HSP 1 Score: 233.417 bits (594), Expect = 5.179e-75
Identity = 118/256 (46.09%), Postives = 165/256 (64.45%), Query Frame = 2

Query:   77 RCFSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTK-----QSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            R +S  N+  WF +LFV K+D   ++ S LL+K  +S LY+   HNVKP    EYL  Y    E +  K          L+G+W T  GEQD A HLWRF   +P L       +++ ++ EFR+ R++ML  R+NQ+L  FS+W E QPR   + I+ELR+Y LKPGTMIEWGN+WAR I+ R+++ E + G F+ +G++++VHH+WAYKDL+ R++ RN AWR  GWDE V +TVPL+RHM S I+   K SP+
Sbjct:   33 RFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKP----EYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPN-IYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPL 283

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BLAST of NIPSNAP domain-containing protein vs. Ensembl Human
Match: NIPSNAP2 (nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:4179])

HSP 1 Score: 223.787 bits (569), Expect = 3.385e-71
Identity = 114/245 (46.53%), Postives = 158/245 (64.49%), Query Frame = 2

Query:   98 DNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMI-KTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            ++ W  +LFVRK+D   ++ S+LLAK  +S LY+   HNVKP  +  Y          I + K     L+G+W T  GEQD A HLWR++  +P L +     R + +F EFRK R++ML  RKNQ+L  FS+W E  PR S  +I+ELRSY L+PGTMIEWGN+WAR IR R+  +E + G F+ +G ++MVHH+WAY+DL+ R+ +RN AW   GW+E V +TVPLI+ M S I+   K SP+
Sbjct:   42 EDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPR-SGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPL 285

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BLAST of NIPSNAP domain-containing protein vs. Ensembl Human
Match: NIPSNAP2 (nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:4179])

HSP 1 Score: 172.17 bits (435), Expect = 1.206e-51
Identity = 97/243 (39.92%), Postives = 139/243 (57.20%), Query Frame = 2

Query:   98 DNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKDFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            ++ W  +LFVRK+D   ++ S+LLAK  +S LY+                   R+ ++  T      L+  W   +G +  A                   R+  +F EFRK R++ML  RKNQ+L  FS+W E  PR S  +I+ELRSY L+PGTMIEWGN+WAR IR R+  +E + G F+ +G ++MVHH+WAY+DL+ R+ +RN AW   GW+E V +TVPLI+ M S I+   K SP+
Sbjct:   42 EDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKLQFKRC-----------CQRFTKINTT------LVLWWG--LGTRGMAS------------------RTKLEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPR-SGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPL 246

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BLAST of NIPSNAP domain-containing protein vs. Ensembl Human
Match: NIPSNAP1 (nipsnap homolog 1 [Source:HGNC Symbol;Acc:HGNC:7827])

HSP 1 Score: 137.887 bits (346), Expect = 9.940e-39
Identity = 77/175 (44.00%), Postives = 105/175 (60.00%), Query Frame = 2

Query:   83 FSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTK-----QSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHW 583
            +S  N+  WF +LFV K+D   ++ S LL+K  +S LY+   HNVKP    EYL  Y    E +  K          L+G+W T  GEQD A HLWRF   +P L       +++ ++ EFR+ R++ML  R+NQ+L  FS+W E QPR   + I+ELR+Y LKPGTMIEWGN+W
Sbjct:   52 YSKDNEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKP----EYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPN-IYELRTYKLKPGTMIEWGNNW 221

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Human
Match: NIPSNAP2 (nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:4179])

HSP 1 Score: 105.531 bits (262), Expect = 1.194e-27
Identity = 54/104 (51.92%), Postives = 70/104 (67.31%), Query Frame = 2

Query:  275 KQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHW 583
            K     L+G+W T  GEQD A HLWR++  +P L +     R + +F EFRK R++ML  RKNQ+L  FS+W E  PR S  +I+ELRSY L+PGTMIEWGN+W
Sbjct:   12 KHYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPR-SGPNIYELRSYQLRPGTMIEWGNYW 114

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BLAST of NIPSNAP domain-containing protein vs. Ensembl Celegans
Match: K02D10.1 (Putative NipSnap protein K02D10.1 [Source:UniProtKB/Swiss-Prot;Acc:P34492])

HSP 1 Score: 175.252 bits (443), Expect = 9.997e-53
Identity = 87/226 (38.50%), Postives = 129/226 (57.08%), Query Frame = 2

Query:  149 ESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGE-QDTAYHLWRF-KDFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            +S S LL+ S  +YEF  HN +P     YL  + +Y   +  K    EL+GSWT   G  +D A HLWR  K +  +D    L+  D+          ++   RKN I+  FSYW E + R   + +++LRSY L+PGTMI+W + WA+GI+ R++ ++ + G F  VG +++V+H+WAY  +  R   R+  W  PGWD  V +TVPLI+ M S IL  TK+S +
Sbjct:   64 QSHSSLLSNSELMYEFMTHNYRPGEQDAYLDAFGKYKNEMNQKNPSIELVGSWTCAYGRTRDQAIHLWRHNKGYEDVDSSISLHGKDSGIRAADNDVAKLCGRRKNLIVKSFSYWREPEQR-PPNHVYDLRSYVLQPGTMIDWASAWAKGIQYRREANQDVGGFFAQVGQLYVVYHIWAYPSMSGRNDTRHATWAKPGWDATVANTVPLIKKMQSKILTPTKYSQL 288

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Query:  149 ESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGE-QDTAYHLWRF-KDFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            +S S LL+ S  +YEF  HN +P     YL  + +Y   +  K    EL+GSWT   G  +D A HLWR  K +  +D    L+  D+          ++   RKN I+  FSYW E + R   + +++LRSY L+PGTMI+W + WA+GI+ R++ ++ + G F  VG +++V+H+WAY  +  R   R+  W  PGWD  V +TVPLI+ M S IL  TK+S +
Sbjct:   64 QSHSSLLSNSELMYEFMTHNYRPGEQDAYLDAFGKYKNEMNQKNPSIELVGSWTCAYGRTRDQAIHLWRHNKGYEDVDSSISLHGKDSGIRAADNDVAKLCGRRKNLIVKSFSYWREPEQR-PPNHVYDLRSYVLQPGTMIDWASAWAKGIQYRREANQDVGGFFAQVGQLYVVYHIWAYPSMSGRNDTRHATWAKPGWDATVANTVPLIKKMQSKILTPTKYSQL 288

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Celegans
Match: K02D10.1 (Putative NipSnap protein K02D10.1 [Source:UniProtKB/Swiss-Prot;Acc:P34492])

HSP 1 Score: 175.252 bits (443), Expect = 1.831e-50
Identity = 87/224 (38.84%), Postives = 128/224 (57.14%), Query Frame = 2

Query:  149 ESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGE-QDTAYHLWRF-KDFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFS 814
            +S S LL+ S  +YEF  HN +P     YL  + +Y   +  K    EL+GSWT   G  +D A HLWR  K +  +D    L+  D+          ++   RKN I+  FSYW E + R  +  +++LRSY L+PGTMI+W + WA+GI+ R++ ++ + G F  VG +++V+H+WAY  +  R   R+  W  PGWD  V +TVPLI+ M S IL  TK+S
Sbjct:  301 QSHSSLLSNSELMYEFMTHNYRPGEQDAYLDAFGKYKNEMNQKNPSIELVGSWTCAYGRTRDQAIHLWRHNKGYEDVDSSISLHGKDSGIRAADNDVAKLCGRRKNLIVKSFSYWREPEQRPPN-HVYDLRSYVLQPGTMIDWASAWAKGIQYRREANQDVGGFFAQVGQLYVVYHIWAYPSMSGRNDTRHATWAKPGWDATVANTVPLIKKMQSKILTPTKYS 523

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Fly
Match: Nipsnap (gene:FBgn0030724 transcript:FBtr0074259)

HSP 1 Score: 224.942 bits (572), Expect = 3.517e-72
Identity = 113/269 (42.01%), Postives = 162/269 (60.22%), Query Frame = 2

Query:   32 LR*MFKFIRLRNHFNRCFSTG---NDNK-WFGNLFVRKLDSVHESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQS--GAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSP 817
            LR +    +  N+  R  ST    ND++ WF  L VRK++   ES S +L+    +Y  H HNV+P  M  YL +Y     +I  K++    EL+ SWT ++G+ D   HLW++   F  +D+      +D ++    + R++ L  R  Q L  FSYWP+I  R +  +I+E+RSY L PGTMIEWGN+WAR I  RK ++E  AG F+ +G ++ VHH+W YK L+ RK+ R  AWR+PGWDECV +TVPLIR M+  +L  T+FSP
Sbjct:    4 LRNLLAVGKSNNNAVRSLSTTPSRNDSESWFSKLLVRKIEPTKESHSRMLSDKEIIYALHTHNVRPDSMGSYLNNYKTTVALINEKKANLSCELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDPEYLSLMQERSKFLRSRHLQYLLAFSYWPQIASR-TGKNIYEMRSYRLTPGTMIEWGNNWARAINYRKHNNEAFAGFFSQIGRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTVPLIREMHCRVLAPTEFSP 271

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Fly
Match: Nipsnap (gene:FBgn0030724 transcript:FBtr0343595)

HSP 1 Score: 224.942 bits (572), Expect = 3.517e-72
Identity = 113/269 (42.01%), Postives = 162/269 (60.22%), Query Frame = 2

Query:   32 LR*MFKFIRLRNHFNRCFSTG---NDNK-WFGNLFVRKLDSVHESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQS--GAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSP 817
            LR +    +  N+  R  ST    ND++ WF  L VRK++   ES S +L+    +Y  H HNV+P  M  YL +Y     +I  K++    EL+ SWT ++G+ D   HLW++   F  +D+      +D ++    + R++ L  R  Q L  FSYWP+I  R +  +I+E+RSY L PGTMIEWGN+WAR I  RK ++E  AG F+ +G ++ VHH+W YK L+ RK+ R  AWR+PGWDECV +TVPLIR M+  +L  T+FSP
Sbjct:    4 LRNLLAVGKSNNNAVRSLSTTPSRNDSESWFSKLLVRKIEPTKESHSRMLSDKEIIYALHTHNVRPDSMGSYLNNYKTTVALINEKKANLSCELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDPEYLSLMQERSKFLRSRHLQYLLAFSYWPQIASR-TGKNIYEMRSYRLTPGTMIEWGNNWARAINYRKHNNEAFAGFFSQIGRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTVPLIREMHCRVLAPTEFSP 271

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Fly
Match: Nipsnap (gene:FBgn0030724 transcript:FBtr0074257)

HSP 1 Score: 224.942 bits (572), Expect = 3.517e-72
Identity = 113/269 (42.01%), Postives = 162/269 (60.22%), Query Frame = 2

Query:   32 LR*MFKFIRLRNHFNRCFSTG---NDNK-WFGNLFVRKLDSVHESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQS--GAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSP 817
            LR +    +  N+  R  ST    ND++ WF  L VRK++   ES S +L+    +Y  H HNV+P  M  YL +Y     +I  K++    EL+ SWT ++G+ D   HLW++   F  +D+      +D ++    + R++ L  R  Q L  FSYWP+I  R +  +I+E+RSY L PGTMIEWGN+WAR I  RK ++E  AG F+ +G ++ VHH+W YK L+ RK+ R  AWR+PGWDECV +TVPLIR M+  +L  T+FSP
Sbjct:    4 LRNLLAVGKSNNNAVRSLSTTPSRNDSESWFSKLLVRKIEPTKESHSRMLSDKEIIYALHTHNVRPDSMGSYLNNYKTTVALINEKKANLSCELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDPEYLSLMQERSKFLRSRHLQYLLAFSYWPQIASR-TGKNIYEMRSYRLTPGTMIEWGNNWARAINYRKHNNEAFAGFFSQIGRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTVPLIREMHCRVLAPTEFSP 271

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Fly
Match: Nipsnap (gene:FBgn0030724 transcript:FBtr0074258)

HSP 1 Score: 224.942 bits (572), Expect = 3.517e-72
Identity = 113/269 (42.01%), Postives = 162/269 (60.22%), Query Frame = 2

Query:   32 LR*MFKFIRLRNHFNRCFSTG---NDNK-WFGNLFVRKLDSVHESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQS--GAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSP 817
            LR +    +  N+  R  ST    ND++ WF  L VRK++   ES S +L+    +Y  H HNV+P  M  YL +Y     +I  K++    EL+ SWT ++G+ D   HLW++   F  +D+      +D ++    + R++ L  R  Q L  FSYWP+I  R +  +I+E+RSY L PGTMIEWGN+WAR I  RK ++E  AG F+ +G ++ VHH+W YK L+ RK+ R  AWR+PGWDECV +TVPLIR M+  +L  T+FSP
Sbjct:    4 LRNLLAVGKSNNNAVRSLSTTPSRNDSESWFSKLLVRKIEPTKESHSRMLSDKEIIYALHTHNVRPDSMGSYLNNYKTTVALINEKKANLSCELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDPEYLSLMQERSKFLRSRHLQYLLAFSYWPQIASR-TGKNIYEMRSYRLTPGTMIEWGNNWARAINYRKHNNEAFAGFFSQIGRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTVPLIREMHCRVLAPTEFSP 271

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Zebrafish
Match: nipsnap1 (nipsnap homolog 1 (C. elegans) [Source:NCBI gene;Acc:30231])

HSP 1 Score: 225.328 bits (573), Expect = 3.531e-72
Identity = 114/253 (45.06%), Postives = 162/253 (64.03%), Query Frame = 2

Query:   77 RCFSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEY--LADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            R F+  +D  W  ++F  K+D+  ++ S+LL+K  +S LY+   HNVKP YM EY  L+D  +  E+        E++GSW T  GEQD A HLWR+   +P L +  R    +  +  FRK R++ML  R+NQ+L  FS+W E  PR S  +I+ELRSY L PGTMIEWGNHWAR I+ R++++E + G FT +GD+++VHH+WAYKDL+ R++ R  AW   GWD  V +T+PLI+ M S I+     SP+
Sbjct:   28 RGFANKSDEGWLSSMFAHKVDARKDAHSNLLSKKETSNLYKIQFHNVKPEYMEEYNKLSDEVQ-KELHHDTDYPCEVVGSWNTWYGEQDQAVHLWRYSGGYPALTECLRKLNLNTAYLAFRKERSKMLLSRRNQLLLEFSFWNEPVPR-SGSNIYELRSYQLLPGTMIEWGNHWARAIKYRQENNEAVGGFFTQIGDLYVVHHLWAYKDLQSREETRKAAWEKEGWDVSVHYTMPLIQKMESRIMIPMVHSPL 278

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Zebrafish
Match: nipsnap2 (pep chromosome:GRCz11:15:404891:413541:1 gene:ENSDARG00000007264.11 transcript:ENSDART00000155682.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:nipsnap2)

HSP 1 Score: 164.851 bits (416), Expect = 1.302e-48
Identity = 92/219 (42.01%), Postives = 129/219 (58.90%), Query Frame = 2

Query:  191 EFHIHNVKPAYMSEYLADYARYNEMIKT-----KQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYF---RKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            +  IHNVKP    E L  Y +  E + T     K    EL+G+W T  GEQD A HLWR++  +P L +     +++   + +      ML+    R+N +    SY   I  R  +  +F L S+ LKPGTMIEWGN+WAR I  R+ + E + G F+ +GD++MVHH+WAYKDL+ R+  RN AW++ GWDE V +TVPLI+HM S I+   K SP+
Sbjct:   72 QLQIHNVKP----ECLEAYNKLCEDVLTNIHTDKAYPCELVGTWNTWYGEQDQAVHLWRYRGGYPALTEVMSKLKNNKVIQHYYN--PNMLFLLSDRQNMLKHESSYITYIITR-DETELFILISFQLKPGTMIEWGNYWARAIGYRQHNREAVGGFFSQIGDLYMVHHLWAYKDLQSREDTRNAAWQHEGWDEVVYYTVPLIQHMESRIMIPLKNSPL 283

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BLAST of NIPSNAP domain-containing protein vs. Ensembl Zebrafish
Match: nipsnap3a (nipsnap homolog 3A (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-1037])

HSP 1 Score: 72.4034 bits (176), Expect = 3.147e-14
Identity = 47/216 (21.76%), Postives = 96/216 (44.44%), Query Frame = 2

Query:  182 TLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKDFPILDKHYRLYRSDADF-EEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHW--ARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            T YEF  + ++P   + +L      NE I+ + + +EL+G WT E G  +  +H+W++  +            D  + E++  +   ML  + N++ +    W +IQ    +  +FEL ++ +K G    WG  +  A G      ++  +    +  G ++ VH +W Y+  + R  +R+ +  +      V  +   +    + ++    FSPI
Sbjct:   60 TFYEFRTYYIQPHLNAAFLK---LTNEKIQLRTAHSELIGYWTVEYGGLNQVFHIWKYDSYAQRASVRAALAQDPSWNEQYISKAMPMLSSQDNEVTY-LVPWSKIQKPPKEGGVFELATFQMKSGGPAVWGKAFQAAVGTHTGSGYAHSVGVFHSEFGQLNQVHVLWWYESADQRAAVRHTSHEDARVVAAVRESALYLVAQKNKLMFPCSFSPI 271

HSP 2 Score: 52.373 bits (124), Expect = 2.086e-7
Identity = 31/132 (23.48%), Postives = 58/132 (43.94%), Query Frame = 2

Query:  428 RRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDE-CVLHTVPLIRHMNSNILRATKFSPI 820
            R  E     KN++  P + W    P+Q   + +E R+Y ++P     +       I++R  HSE I       G ++ V H+W Y     R  +R    ++P W+E  +   +P++   ++ +     +S I
Sbjct:   30 RHAERCLTVKNRLTQPSAAWITTGPQQQHGTFYEFRTYYIQPHLNAAFLKLTNEKIQLRTAHSELIGYWTVEYGGLNQVFHIWKYDSYAQRASVRAALAQDPSWNEQYISKAMPMLSSQDNEVTYLVPWSKI 161

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BLAST of NIPSNAP domain-containing protein vs. Ensembl Xenopus
Match: nipsnap2 (nipsnap homolog 2 [Source:NCBI gene;Acc:733910])

HSP 1 Score: 234.187 bits (596), Expect = 1.864e-75
Identity = 121/254 (47.64%), Postives = 160/254 (62.99%), Query Frame = 2

Query:   83 FSTGNDNKWFGNLFVRKLDSVHESQSDLLAKS--STLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAE-----LMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            +S   ++ W  +LFVRK+D   ++ S+LLAK   S LY+   HNVKP    E L  Y +  E +  K    E     L+G+W T  GEQD A HLW+++  +P L +     R + +F EFRK R  ML  RKNQ+L  FS+W E  PR   + I+ELRSY L+PGTMIEWGNHWAR IR R+   E +AG F+ +G ++MVHH+WAYKDL+ R  +RN AW+  GWDECV +TVPLI+ M S I+   K SP+
Sbjct:   28 YSKAREDSWLRSLFVRKVDPRKDAHSNLLAKKEISNLYKIQFHNVKP----ECLESYNKLCEEVLPKIHADEDYPCTLVGTWNTWYGEQDQAVHLWKYEGGYPALTEVMSKLRKNKEFTEFRKARGNMLLSRKNQLLLEFSFWNEPVPRNGPN-IYELRSYQLRPGTMIEWGNHWARAIRYRQDGDEAVAGFFSQIGHLYMVHHLWAYKDLQTRDDIRNSAWQKDGWDECVYYTVPLIQEMESRIMIPLKSSPL 276

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Xenopus
Match: nipsnap2 (nipsnap homolog 2 [Source:NCBI gene;Acc:733910])

HSP 1 Score: 232.646 bits (592), Expect = 9.221e-75
Identity = 120/251 (47.81%), Postives = 158/251 (62.95%), Query Frame = 2

Query:   92 GNDNKWFGNLFVRKLDSVHESQSDLLAKS--STLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAE-----LMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
              ++ W  +LFVRK+D   ++ S+LLAK   S LY+   HNVKP    E L  Y +  E +  K    E     L+G+W T  GEQD A HLW+++  +P L +     R + +F EFRK R  ML  RKNQ+L  FS+W E  PR   + I+ELRSY L+PGTMIEWGNHWAR IR R+   E +AG F+ +G ++MVHH+WAYKDL+ R  +RN AW+  GWDECV +TVPLI+ M S I+   K SP+
Sbjct:   36 AREDSWLRSLFVRKVDPRKDAHSNLLAKKEISNLYKIQFHNVKP----ECLESYNKLCEEVLPKIHADEDYPCTLVGTWNTWYGEQDQAVHLWKYEGGYPALTEVMSKLRKNKEFTEFRKARGNMLLSRKNQLLLEFSFWNEPVPRNGPN-IYELRSYQLRPGTMIEWGNHWARAIRYRQDGDEAVAGFFSQIGHLYMVHHLWAYKDLQTRDDIRNSAWQKDGWDECVYYTVPLIQEMESRIMIPLKSSPL 281

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Xenopus
Match: mgat2 (mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [Source:Xenbase;Acc:XB-GENE-978789])

HSP 1 Score: 222.631 bits (566), Expect = 5.104e-71
Identity = 116/258 (44.96%), Postives = 166/258 (64.34%), Query Frame = 2

Query:   80 CFSTGNDNK---WFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTK-----QSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            CF  G+D++   W  +LFVRK+D   ++ S LL+K  +S LY+   HNVKP    E L +Y R  E +  K         +L+G+W T  GEQD A HLWRF   +P L       R++ ++  FR+ R++ML  R+NQ+L  FS+W E  PR+  + I+ELR+Y LKPGTMIEWGN+WAR I+ R+++ E + G F+ +G++++VHH+WAYKDLE R++ R  AW   GWDE V +TVPL+R+M S I+   K SP+
Sbjct:   20 CFRYGSDSRDSSWLRSLFVRKVDPRKDAHSTLLSKKETSGLYKMQFHNVKP----ECLEEYNRLTEEVLPKLHHDPDYHCDLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLRNNKEYLAFREERSKMLLSRRNQLLLEFSFWNEPAPRKGPN-IYELRTYRLKPGTMIEWGNNWARAIKHRQENQEAVGGFFSQIGELYVVHHLWAYKDLESREETRKAAWTKRGWDENVYYTVPLVRNMESRIMIPLKISPL 272

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Xenopus
Match: mgat2 (mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [Source:Xenbase;Acc:XB-GENE-978789])

HSP 1 Score: 221.861 bits (564), Expect = 3.332e-70
Identity = 114/253 (45.06%), Postives = 162/253 (64.03%), Query Frame = 2

Query:   86 STGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTK-----QSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            S   D+ W  +LFVRK+D   ++ S LL+K  +S LY+   HNVKP    E L +Y R  E +  K         +L+G+W T  GEQD A HLWRF   +P L       R++ ++  FR+ R++ML  R+NQ+L  FS+W E  PR+  + I+ELR+Y LKPGTMIEWGN+WAR I+ R+++ E + G F+ +G++++VHH+WAYKDLE R++ R  AW   GWDE V +TVPL+R+M S I+   K SP+
Sbjct:   65 SDSRDSSWLRSLFVRKVDPRKDAHSTLLSKKETSGLYKMQFHNVKP----ECLEEYNRLTEEVLPKLHHDPDYHCDLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLRNNKEYLAFREERSKMLLSRRNQLLLEFSFWNEPAPRKGPN-IYELRTYRLKPGTMIEWGNNWARAIKHRQENQEAVGGFFSQIGELYVVHHLWAYKDLESREETRKAAWTKRGWDENVYYTVPLVRNMESRIMIPLKISPL 312

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Xenopus
Match: mgat2 (mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [Source:Xenbase;Acc:XB-GENE-978789])

HSP 1 Score: 220.32 bits (560), Expect = 3.377e-70
Identity = 115/256 (44.92%), Postives = 163/256 (63.67%), Query Frame = 2

Query:   77 RCFSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTK-----QSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            R  S   D+ W  +LFVRK+D   ++ S LL+K  +S LY+   HNVKP    E L +Y R  E +  K         +L+G+W T  GEQD A HLWRF   +P L       R++ ++  FR+ R++ML  R+NQ+L  FS+W E  PR+  + I+ELR+Y LKPGTMIEWGN+WAR I+ R+++ E + G F+ +G++++VHH+WAYKDLE R++ R  AW   GWDE V +TVPL+R+M S I+   K SP+
Sbjct:   19 RYGSDSRDSSWLRSLFVRKVDPRKDAHSTLLSKKETSGLYKMQFHNVKP----ECLEEYNRLTEEVLPKLHHDPDYHCDLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLRNNKEYLAFREERSKMLLSRRNQLLLEFSFWNEPAPRKGPN-IYELRTYRLKPGTMIEWGNNWARAIKHRQENQEAVGGFFSQIGELYVVHHLWAYKDLESREETRKAAWTKRGWDENVYYTVPLVRNMESRIMIPLKISPL 269

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Mouse
Match: Nipsnap1 (nipsnap homolog 1 [Source:MGI Symbol;Acc:MGI:1278344])

HSP 1 Score: 229.565 bits (584), Expect = 1.105e-73
Identity = 117/256 (45.70%), Postives = 165/256 (64.45%), Query Frame = 2

Query:   77 RCFSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTK-----QSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            R +S  ++  WF +LFV K+D   ++ S LL+K  +S LY+   HNVKP    E L  Y    E +  K          L+G+W T  GEQD A HLWRF   +P L       +++ ++ EFRK R++ML  R+NQ+L  FS+W E QPR +  +I+ELR+Y LKPGTMIEWGN+WAR I+ R+++ E + G F+ +G++++VHH+WAYKDL+ R++ RN AWR  GWDE V +TVPL+RHM S I+   K SP+
Sbjct:   33 RFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKP----ECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPR-AGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPL 283

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Mouse
Match: Nipsnap2 (nipsnap homolog 2 [Source:MGI Symbol;Acc:MGI:1278343])

HSP 1 Score: 223.402 bits (568), Expect = 2.173e-71
Identity = 113/245 (46.12%), Postives = 158/245 (64.49%), Query Frame = 2

Query:   98 DNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMI-KTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            ++ W  +LFVRK+D   ++ S+LLAK  +S+LY+   HNVKP  +  Y          I + KQ    L+G+W T  GEQD A HLWR++  +P L +     + + +F  FRK R++ML  RKNQ+L  FS+W E  PR   + I+ELRSY L+PGTMIEWGN+WAR IR R+  +E + G F+ +G ++MVHH+WAYKDL+ R+ +RN AW   GW+E V +TVPLI+ M S I+   K SP+
Sbjct:   37 EDSWLKSLFVRKVDPRKDAHSNLLAKKETSSLYKLQFHNVKPECLDAYNKICQEVLPKIHEGKQYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLKENQEFVNFRKARSDMLLSRKNQLLLEFSFWNEPVPRPGPN-IYELRSYQLRPGTMIEWGNYWARAIRFRQDSNEAVGGFFSQIGQLYMVHHLWAYKDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPL 280

[Close]

Query:   98 DNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMI-KTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            ++ W  +LFVRK+D   ++ S+LLAK  +S+LY+   HNVKP  +  Y          I + KQ    L+G+W T  GEQD A HLWR++  +P L +     + + +F  FRK R++ML  RKNQ+L  FS+W E  PR   + I+ELRSY L+PGTMIEWGN+WAR IR R+  +E + G F+ +G ++MVHH+WAYKDL+ R+ +RN AW   GW+E V +TVPLI+ M S I+   K SP+
Sbjct:   37 EDSWLKSLFVRKVDPRKDAHSNLLAKKETSSLYKLQFHNVKPECLDAYNKICQEVLPKIHEGKQYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLKENQEFVNFRKARSDMLLSRKNQLLLEFSFWNEPVPRPGPN-IYELRSYQLRPGTMIEWGNYWARAIRFRQDSNEAVGGFFSQIGQLYMVHHLWAYKDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPL 280

[Close]

Query:   98 DNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMI-KTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            ++ W  +LFVRK+D   ++ S+LLAK  +S+LY+   HNVKP  +  Y          I + KQ    L+G+W T  GEQD A HLWR++  +P L +     + + +F  FRK R++ML  RKNQ+L  FS+W E  PR   + I+ELRSY L+PGTMIEWGN+WAR IR R+  +E + G F+ +G ++MVHH+WAYKDL+ R+ +RN AW   GW+E V +TVPLI+ M S I+   K SP+
Sbjct:   37 EDSWLKSLFVRKVDPRKDAHSNLLAKKETSSLYKLQFHNVKPECLDAYNKICQEVLPKIHEGKQYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLKENQEFVNFRKARSDMLLSRKNQLLLEFSFWNEPVPRPGPN-IYELRSYQLRPGTMIEWGNYWARAIRFRQDSNEAVGGFFSQIGQLYMVHHLWAYKDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPL 280

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Mouse
Match: Nipsnap1 (nipsnap homolog 1 [Source:MGI Symbol;Acc:MGI:1278344])

HSP 1 Score: 71.633 bits (174), Expect = 5.186e-15
Identity = 46/127 (36.22%), Postives = 67/127 (52.76%), Query Frame = 2

Query:   83 FSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTK-----QSGAELMGSWTTEIGEQDTAYHLWRFK-DFPILDKHYRLYRSDADFEEFRKRRNE 439
            +S  ++  WF +LFV K+D   ++ S LL+K  +S LY+   HNVKP    E L  Y    E +  K          L+G+W T  GEQD A HLWRF   +P L       +++ ++ EFRK R++
Sbjct:   14 YSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKP----ECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRKERSK 136

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BLAST of NIPSNAP domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9BPW8|NIPS1_HUMAN (Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1)

HSP 1 Score: 233.417 bits (594), Expect = 2.487e-74
Identity = 118/256 (46.09%), Postives = 165/256 (64.45%), Query Frame = 2

Query:   77 RCFSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTK-----QSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            R +S  N+  WF +LFV K+D   ++ S LL+K  +S LY+   HNVKP    EYL  Y    E +  K          L+G+W T  GEQD A HLWRF   +P L       +++ ++ EFR+ R++ML  R+NQ+L  FS+W E QPR   + I+ELR+Y LKPGTMIEWGN+WAR I+ R+++ E + G F+ +G++++VHH+WAYKDL+ R++ RN AWR  GWDE V +TVPL+RHM S I+   K SP+
Sbjct:   33 RFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKP----EYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPN-IYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPL 283

[Close]

BLAST of NIPSNAP domain-containing protein vs. UniProt/SwissProt
Match: sp|O55125|NIPS1_MOUSE (Protein NipSnap homolog 1 OS=Mus musculus OX=10090 GN=Nipsnap1 PE=1 SV=1)

HSP 1 Score: 229.565 bits (584), Expect = 7.730e-73
Identity = 117/256 (45.70%), Postives = 165/256 (64.45%), Query Frame = 2

Query:   77 RCFSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTK-----QSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            R +S  ++  WF +LFV K+D   ++ S LL+K  +S LY+   HNVKP    E L  Y    E +  K          L+G+W T  GEQD A HLWRF   +P L       +++ ++ EFRK R++ML  R+NQ+L  FS+W E QPR +  +I+ELR+Y LKPGTMIEWGN+WAR I+ R+++ E + G F+ +G++++VHH+WAYKDL+ R++ RN AWR  GWDE V +TVPL+RHM S I+   K SP+
Sbjct:   33 RFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKP----ECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPR-AGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPL 283

[Close]

BLAST of NIPSNAP domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9VXK0|NIPSN_DROME (Protein NipSnap OS=Drosophila melanogaster OX=7227 GN=Nipsnap PE=2 SV=2)

HSP 1 Score: 224.942 bits (572), Expect = 3.526e-71
Identity = 113/269 (42.01%), Postives = 162/269 (60.22%), Query Frame = 2

Query:   32 LR*MFKFIRLRNHFNRCFSTG---NDNK-WFGNLFVRKLDSVHESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQS--GAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSP 817
            LR +    +  N+  R  ST    ND++ WF  L VRK++   ES S +L+    +Y  H HNV+P  M  YL +Y     +I  K++    EL+ SWT ++G+ D   HLW++   F  +D+      +D ++    + R++ L  R  Q L  FSYWP+I  R +  +I+E+RSY L PGTMIEWGN+WAR I  RK ++E  AG F+ +G ++ VHH+W YK L+ RK+ R  AWR+PGWDECV +TVPLIR M+  +L  T+FSP
Sbjct:    4 LRNLLAVGKSNNNAVRSLSTTPSRNDSESWFSKLLVRKIEPTKESHSRMLSDKEIIYALHTHNVRPDSMGSYLNNYKTTVALINEKKANLSCELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDPEYLSLMQERSKFLRSRHLQYLLAFSYWPQIASR-TGKNIYEMRSYRLTPGTMIEWGNNWARAINYRKHNNEAFAGFFSQIGRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTVPLIREMHCRVLAPTEFSP 271

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BLAST of NIPSNAP domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9PU58|NIPS2_DANRE (Protein NipSnap homolog 2 OS=Danio rerio OX=7955 GN=nipsnap2 PE=2 SV=2)

HSP 1 Score: 225.328 bits (573), Expect = 3.977e-71
Identity = 116/249 (46.59%), Postives = 161/249 (64.66%), Query Frame = 2

Query:   98 DNKWFGNLFVRKLDSVHESQSDLLAKS--STLYEFHIHNVKPAYMSEYLADYARYNEMIKT-----KQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            ++ WF +LFVRK+D   ++ S LLAK   + LY+   HNVKP    E L  Y +  E + T     K    EL+G+W T  GEQD A HLWR++  +P L +     +++ +F E+R  R +ML  R+NQ+L  FS+W E  PR   + I+ELRSY L+PGTMIEWGN+WAR I  R+ + E + G F+ +GD++MVHH+WAYKDL+ R+  RN AW++ GWDE V +TVPLI+HM S I+   K SP+
Sbjct:   42 EDSWFKSLFVRKVDPRKDAHSHLLAKKEDNNLYKIQFHNVKP----ECLEAYNKLCEDVLTNIHTDKAYPCELVGTWNTWYGEQDQAVHLWRYRGGYPALTEVMSKLKNNKEFLEYRSERGKMLLSRRNQLLLEFSFWNEPVPRDGPN-IYELRSYQLRPGTMIEWGNYWARAIGYRQHNREAVGGFFSQIGDLYMVHHLWAYKDLQSREDTRNAAWQHEGWDEVVYYTVPLIQHMESRIMIPLKNSPL 285

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BLAST of NIPSNAP domain-containing protein vs. UniProt/SwissProt
Match: sp|O75323|NIPS2_HUMAN (Protein NipSnap homolog 2 OS=Homo sapiens OX=9606 GN=NIPSNAP2 PE=1 SV=1)

HSP 1 Score: 223.787 bits (569), Expect = 1.625e-70
Identity = 114/245 (46.53%), Postives = 158/245 (64.49%), Query Frame = 2

Query:   98 DNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMI-KTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            ++ W  +LFVRK+D   ++ S+LLAK  +S LY+   HNVKP  +  Y          I + K     L+G+W T  GEQD A HLWR++  +P L +     R + +F EFRK R++ML  RKNQ+L  FS+W E  PR S  +I+ELRSY L+PGTMIEWGN+WAR IR R+  +E + G F+ +G ++MVHH+WAY+DL+ R+ +RN AW   GW+E V +TVPLI+ M S I+   K SP+
Sbjct:   42 EDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPR-SGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPL 285

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BLAST of NIPSNAP domain-containing protein vs. TrEMBL
Match: A0A4S2LSE9 (NIPSNAP domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006414 PE=4 SV=1)

HSP 1 Score: 280.411 bits (716), Expect = 2.189e-90
Identity = 132/254 (51.97%), Postives = 178/254 (70.08%), Query Frame = 2

Query:   62 RNHFNRCFSTGND--NKWFGNLFVRKLDSVHESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFS 814
            ++ F R  ST +D  + W  ++  R  DS  ESQS LL+ + T++E   H VKP +M EYL +   +  ++    S +EL+GSWT EIG QDTAYHLWR+   +P L +H  +YRS  +  E R RRN ML+ RKN+I   FS+WP+  PR  +++I+ELRSY LKPGTMIEWGNHWARG+R+R +  EP+AGLF+H+G++H VHH+WAY  LE R+K R++ W++P W +CV+HTVPLIR M SNILR T FS
Sbjct:   26 KSCFRRWASTKHDRGDSWLASMLGRS-DS-KESQSGLLSNTVTIFELQTHVVKPQFMCEYLKEMEHFVNVLSKTDSNSELLGSWTCEIGFQDTAYHLWRYSSGYPGLSQHTEIYRSHKELTESRHRRNVMLHTRKNEICLTFSFWPDPTPRPDENNIYELRSYALKPGTMIEWGNHWARGLRLRSKQREPVAGLFSHIGELHQVHHLWAYNSLEARQKSRDDTWQDPDWSKCVMHTVPLIRRMTSNILRPTPFS 277

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BLAST of NIPSNAP domain-containing protein vs. TrEMBL
Match: A0A074YZ70 (NIPSNAP domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_11374 PE=4 SV=1)

HSP 1 Score: 280.411 bits (716), Expect = 2.362e-90
Identity = 131/254 (51.57%), Postives = 178/254 (70.08%), Query Frame = 2

Query:   62 RNHFNRCFSTGND--NKWFGNLFVRKLDSVHESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFK-DFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFS 814
            ++ F R  ST +D  + W  ++  R  DS  ESQS LL+ + T++E   H VKP +M EYL +   +  ++    S +EL+GSWT EIG QDTAYHLW++   +P L +H  +YRS  +  E R RRN ML+ RKN+I   FS+WP+  PR  +++I+ELRSY LKPGTMIEWGNHWARG+R+R +  EP+AGLF+H+G++H VHH+WAY  LE R+K R++ W++P W +CV+HTVPLIR M SNILR T FS
Sbjct:   26 KSFFKRWASTKHDRGDSWLASMLSRS-DS-KESQSGLLSNTVTIFELQTHVVKPQFMCEYLKEMEHFVNVLSKTDSNSELLGSWTCEIGFQDTAYHLWKYSAGYPGLSQHTEIYRSHKELTESRHRRNVMLHTRKNEICLTFSFWPDPTPRPDENNIYELRSYALKPGTMIEWGNHWARGLRLRSKQREPVAGLFSHIGELHQVHHLWAYSSLEARQKSRDDTWQDPDWSKCVMHTVPLIRRMTSNILRPTPFS 277

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BLAST of NIPSNAP domain-containing protein vs. TrEMBL
Match: R7TLM6 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_179650 PE=4 SV=1)

HSP 1 Score: 274.248 bits (700), Expect = 3.530e-88
Identity = 126/240 (52.50%), Postives = 169/240 (70.42%), Query Frame = 2

Query:  107 WFGNLF-VRKLDSVHESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            WF  L  +RK+D   ES S LLA   T+YE  IH+VKP +M +YL +Y  +   +  K++GA+L GSWT EIG+QD A HLW++   +P+L++  R  R++ +F +FR  RN+ML  R+NQIL  FS+W + Q R   + I+ELRSY LKPGTMIEWGN+WARGI+ R++ +E +AG F+ +GD++ VHH+WAY+ LE RK  R  AWR PGWD CV HTVPLIRHM + IL  T FSP+
Sbjct:   31 WFQRLLPIRKIDPGTESHSSLLADKDTVYELQIHSVKPEFMEKYLGEYETFVNRVHNKETGAQLAGSWTVEIGDQDEAIHLWKYSGGYPVLNRSKRTLRTEKEFVDFRISRNKMLRSRRNQILLAFSFWGDPQVRDGSN-IYELRSYVLKPGTMIEWGNNWARGIKTRREKNEAVAGFFSQIGDLYNVHHLWAYESLESRKDTRTSAWRRPGWDACVAHTVPLIRHMTARILVPTPFSPL 269

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BLAST of NIPSNAP domain-containing protein vs. TrEMBL
Match: A0A1S3H692 (protein NipSnap-like isoform X1 OS=Lingula unguis OX=7574 GN=LOC106152561 PE=4 SV=1)

HSP 1 Score: 273.863 bits (699), Expect = 1.050e-87
Identity = 130/264 (49.24%), Postives = 181/264 (68.56%), Query Frame = 2

Query:   68 HFNRCFST--------GNDNK---WFGNLFVRKLDSVHESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSD-DSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
              +RC ST        G D K    F +LFVRK+++ H +QS LL++   +Y+   H+VKP  M  YL  +  + +++K+K +GA L+GSWT EIG+QD A H+W+++  +P+L+    +YR+D DF +FR +RN+ML  R+NQI+  FS+WPE  P Q D  +I+E+R+YTLKPGTMIEWGN W RGI+ R   +E IAG F+H+GD+H VHH W+YK L+ RK++R  AW NPGWDE V +TVPLIR + S IL  T FSP+
Sbjct:   29 QLSRCLSTTFPAFQADGEDGKKQGLFSSLFVRKIEATHVTQSKLLSEPGDVYQIQFHSVKPECMEAYLKQFGTFVDLMKSKDTGASLVGSWTVEIGDQDEAIHVWKYEGGYPVLNDATYIYRTDKDFIDFRLQRNKMLRARRNQIVLRFSFWPE--PVQKDPGNIYEMRTYTLKPGTMIEWGNIWQRGIKHRMSGNEAIAGYFSHIGDLHQVHHFWSYKSLQERKEIRESAWVNPGWDETVAYTVPLIRTLQSRILVPTPFSPL 290

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BLAST of NIPSNAP domain-containing protein vs. TrEMBL
Match: A0A1S3JJF0 (protein NipSnap-like OS=Lingula unguis OX=7574 GN=LOC106173808 PE=4 SV=1)

HSP 1 Score: 273.863 bits (699), Expect = 1.134e-87
Identity = 130/264 (49.24%), Postives = 181/264 (68.56%), Query Frame = 2

Query:   68 HFNRCFST--------GNDNK---WFGNLFVRKLDSVHESQSDLLAKSSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSD-DSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
              +RC ST        G D K    F +LFVRK+++ H +QS LL++   +Y+   H+VKP  M  YL  +  + +++K+K +GA L+GSWT EIG+QD A H+W+++  +P+L+    +YR+D DF +FR +RN+ML  R+NQI+  FS+WPE  P Q D  +I+E+R+YTLKPGTMIEWGN W RGI+ R   +E IAG F+H+GD+H VHH W+YK L+ RK++R  AW NPGWDE V +TVPLIR + S IL  T FSP+
Sbjct:   29 QLSRCLSTTFPAFQADGEDGKKQGLFSSLFVRKIEATHVTQSKLLSEPGDVYQIQFHSVKPECMEAYLKQFGTFVDLMKSKDTGASLVGSWTVEIGDQDEAIHVWKYEGGYPVLNDATYIYRTDKDFIDFRLQRNKMLRARRNQIVLRFSFWPE--PVQKDPGNIYEMRTYTLKPGTMIEWGNIWQRGIKHRMSGNEAIAGYFSHIGDLHQVHHFWSYKSLQERKEIRESAWVNPGWDETVAYTVPLIRTLQSRILVPTPFSPL 290

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000034199.1 (protein NipSnap homolog 2 [Source:NCBI gene;Acc:103034276])

HSP 1 Score: 234.572 bits (597), Expect = 9.833e-76
Identity = 118/249 (47.39%), Postives = 165/249 (66.27%), Query Frame = 2

Query:   98 DNKWFGNLFVRKLDSVHESQSDLLAKS--STLYEFHIHNVKPAYMSEYLADYARYNEMI-----KTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            ++ WF +LFVRK+D   ++ S LLAK   + LY+   HNVKP    E L DY +  E +        Q   EL+G+W T  GEQD A HLWR++  +P L +     R + +F E+R+ R +ML  R+NQ+L  FS+W E  PR S  +I+ELRSY L+PGTMIEWGN+WAR I +R+Q++E + G F+ +G ++MVHH+WAYKDL+ R++ RN AW++ GWDE V +TVPLI+HM S I+   K SP+
Sbjct:   42 EDSWFKSLFVRKVDPRKDAHSHLLAKKEDNNLYKIQFHNVKP----ECLDDYNKLCEAVLPNIHSDPQYPCELVGTWNTWYGEQDQAVHLWRYRGGYPALTEVMNKLRKNKEFMEYREERGKMLLSRRNQLLLEFSFWNEPVPR-SGPNIYELRSYQLRPGTMIEWGNYWARAIELRQQNNEAVGGFFSQIGSLYMVHHLWAYKDLQSREETRNAAWQHEGWDEAVYYTVPLIQHMESRIMIPMKTSPL 285

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Cavefish
Match: nipsnap2 (nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:4179])

HSP 1 Score: 225.328 bits (573), Expect = 3.907e-72
Identity = 116/249 (46.59%), Postives = 158/249 (63.45%), Query Frame = 2

Query:   98 DNKWFGNLFVRKLDSVHESQSDLLAKS--STLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSG-----AELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            +  WF +LFVRK+D   ++ S LLAK   S LY+   HNVKP    E L  Y +  E +            EL+G+W T  GEQD A HLWR++  +P L +     R++ +F E+RK R +ML  R+NQ+L  FS+W E  PR   + I+ELRSY L+PGTMIEWGN+WAR IR R+ + E + G F+ +G ++MVHH+WAYKDL+ R+  RN AW + GW+E V +TVPLI+HM S I+   K SP+
Sbjct:   44 EESWFKSLFVRKVDPRKDAHSHLLAKKEESNLYKIQFHNVKP----ECLDSYNKLCEGVLPSIHADTYYPCELVGTWNTWYGEQDQAVHLWRYRGGYPALTEVMNKLRNNKEFMEYRKERGKMLLSRRNQLLLEFSFWNEPVPRPGPN-IYELRSYQLRPGTMIEWGNYWARAIRYRQHNREAVGGFFSQIGSLYMVHHLWAYKDLQSREATRNAAWHHEGWNEAVYYTVPLIQHMESRIMIPMKSSPL 287

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Cavefish
Match: nipsnap1 (protein NipSnap homolog 1-like [Source:NCBI gene;Acc:103038637])

HSP 1 Score: 219.164 bits (557), Expect = 7.675e-70
Identity = 110/254 (43.31%), Postives = 164/254 (64.57%), Query Frame = 2

Query:   71 FNRCFSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYAR-YNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRF-KDFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
             +R  +  +D  W  ++F  K D+  ++ S+LL+K  +S LY+   HNVKP  +  Y +  A  + E+ +      E++GSW T  GEQD A HLWR+   +P L +     R +  + E+RK R++ML  RK Q+L  FS+W +  PR +  +I+ELR+Y L+PGTMIEWGNHWAR I+ R++++E + G FT +G++++VHH+WAYKDL+ R++ RN AW   GWD  V +TVPLI++M S IL  TK SP+
Sbjct:   25 LSRGLANESDGGWLRSMFAHKADARKDAHSNLLSKKDTSGLYKIQFHNVKPDCLEAYNSLSAEVHKELHRAADYPCEVVGSWNTWYGEQDQAVHLWRYYGGYPALTECLDKLRLNKAYLEYRKERSKMLISRKTQLLMEFSFWNDPVPR-AGPNIYELRTYRLQPGTMIEWGNHWARAIKYRQENNEAVGGFFTQIGELYVVHHLWAYKDLQSREETRNSAWLKEGWDVSVHYTVPLIQNMESRILIPTKSSPL 277

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Cavefish
Match: nipsnap1 (protein NipSnap homolog 1-like [Source:NCBI gene;Acc:103038637])

HSP 1 Score: 217.238 bits (552), Expect = 3.101e-69
Identity = 109/250 (43.60%), Postives = 162/250 (64.80%), Query Frame = 2

Query:   83 FSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYAR-YNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRF-KDFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
             +  +D  W  ++F  K D+  ++ S+LL+K  +S LY+   HNVKP  +  Y +  A  + E+ +      E++GSW T  GEQD A HLWR+   +P L +     R +  + E+RK R++ML  RK Q+L  FS+W +  PR +  +I+ELR+Y L+PGTMIEWGNHWAR I+ R++++E + G FT +G++++VHH+WAYKDL+ R++ RN AW   GWD  V +TVPLI++M S IL  TK SP+
Sbjct:   23 LANESDGGWLRSMFAHKADARKDAHSNLLSKKDTSGLYKIQFHNVKPDCLEAYNSLSAEVHKELHRAADYPCEVVGSWNTWYGEQDQAVHLWRYYGGYPALTECLDKLRLNKAYLEYRKERSKMLISRKTQLLMEFSFWNDPVPR-AGPNIYELRTYRLQPGTMIEWGNHWARAIKYRQENNEAVGGFFTQIGELYVVHHLWAYKDLQSREETRNSAWLKEGWDVSVHYTVPLIQNMESRILIPTKSSPL 271

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Cavefish
Match: nipsnap1 (protein NipSnap homolog 1-like [Source:NCBI gene;Acc:103038637])

HSP 1 Score: 196.438 bits (498), Expect = 3.333e-61
Identity = 98/234 (41.88%), Postives = 149/234 (63.68%), Query Frame = 2

Query:   71 FNRCFSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYAR-YNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRF-KDFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHT 760
             +R  +  +D  W  ++F  K D+  ++ S+LL+K  +S LY+   HNVKP  +  Y +  A  + E+ +      E++GSW T  GEQD A HLWR+   +P L +     R +  + E+RK R++ML  RK Q+L  FS+W +  PR +  +I+ELR+Y L+PGTMIEWGNHWAR I+ R++++E + G FT +G++++VHH+WAYKDL+ R++ RN AW   GWD  V +T
Sbjct:   25 LSRGLANESDGGWLRSMFAHKADARKDAHSNLLSKKDTSGLYKIQFHNVKPDCLEAYNSLSAEVHKELHRAADYPCEVVGSWNTWYGEQDQAVHLWRYYGGYPALTECLDKLRLNKAYLEYRKERSKMLISRKTQLLMEFSFWNDPVPR-AGPNIYELRTYRLQPGTMIEWGNHWARAIKYRQENNEAVGGFFTQIGELYVVHHLWAYKDLQSREETRNSAWLKEGWDVSVHYT 257

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Sea Lamprey
Match: nipsnap2 (nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:4179])

HSP 1 Score: 235.728 bits (600), Expect = 3.629e-77
Identity = 117/259 (45.17%), Postives = 168/259 (64.86%), Query Frame = 2

Query:   71 FNRCFSTGN----DNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEY--LADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            F R  S  +    ++ W  +L V K+D   ++ S+LLAK  SS+L++   HNVKP  +  Y  L + A    +    +   E++GSW T  G+QD A HLWR+K  +P L +   + R +  F EFR+ R++ML  RKNQ+L  FS+W E  PR    SI+ELR+Y+LKPGTMIEWGN+WAR IR R+++SE + G F+ +G+++ VHH+WAY+DL+ R + R  AW+ PGW+ECV +TVPLIR M S ++   KFSP+
Sbjct:    9 FTRALSVASVCHKEDSWLRSLLVHKVDPRKDAHSNLLAKKESSSLFKLQFHNVKPECLDAYNQLTEEALSAFIESGSEYPCEIVGSWNTWYGDQDQAVHLWRYKGGYPALTEAMNMLRQNKKFMEFRRERSKMLISRKNQLLLEFSFWNEPVPR-PGPSIYELRTYSLKPGTMIEWGNNWARAIRYRQENSEAVGGFFSQIGELYNVHHLWAYRDLQSRDETRAAAWQKPGWEECVYYTVPLIRWMESRVMIPLKFSPL 266

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Sea Lamprey
Match: nipsnap3a (nipsnap homolog 3A (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-1037])

HSP 1 Score: 54.299 bits (129), Expect = 6.500e-9
Identity = 42/215 (19.53%), Postives = 91/215 (42.33%), Query Frame = 2

Query:  185 LYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKDFPILDKHYRLYRSDADFEE-FRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQ--HSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            +YE   +   P     +L      NE I  + + + L+G W+ E G      H+W+++D+            D +++E +  +   ML   ++++ +    W ++   +    ++EL ++ +KPG    WG  +   I   +   ++  I    +  G ++ V  +W +   + R   R+ A  +      V  +V  +   ++ +L  T FSP+
Sbjct:   24 MYELRTYTAHPHAFPAFLK---LTNECIHLRTAHSPLIGYWSVEHGPLVQLVHIWQYEDYAQRTAVRAALAKDPEWQETYIAKALPMLCSLESEVTY-LVPWNKLGEPKKQGGVYELVTFDMKPGGPALWGKAFRAAITTHQHVGYASLIGVWHSEFGKLNRVQVLWNFNSADSRAAGRHLAHEDARVVAAVRESVSYVVAQSNKLLLPTPFSPL 234

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Nematostella
Match: EDO40732 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6D8])

HSP 1 Score: 110.923 bits (276), Expect = 6.325e-29
Identity = 64/216 (29.63%), Postives = 110/216 (50.93%), Query Frame = 2

Query:  176 SSTLYEFHIHNVKPAYMSEYLADYARYN-EMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKDFPILDKHYRLYRSDADFE-EFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSP 817
            S  +YE   + +KP    +   DY R   + I  + + ++L G W TE+G  + A H+W + +F    +  +    D  ++ ++  +   ML  ++N I+     W E+Q  QS   I+ELR+YTLK G   +W + W +G+  R ++S P+    + +G ++ V H+W Y   + R ++R EA++   W E V      ++ M S IL  T FSP
Sbjct:   29 SEKIYELRTYAIKP----KDFIDYMRLTYDHIGLRTNHSKLCGFWATELGGLNQAVHIWEYDNFAHRTEVRKALSQDEKWQSQYMAKMMPMLQRQENLIMKAVP-WYEMQKFQSRGGIYELRAYTLKTGKSEQWAHRWLQGLPARCKYSAPVGVWMSEIGTLNQVIHLWQYDSADERVRIRQEAFKEEEWAETVRDCGEFVKKMTSKILIPTNFSP 239

HSP 2 Score: 46.595 bits (109), Expect = 3.895e-6
Identity = 25/102 (24.51%), Postives = 52/102 (50.98%), Query Frame = 2

Query:  503 RQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGW-DECVLHTVPLIRHMNSNILRAT 805
            R + + I+ELR+Y +KP   I++       I +R  HS+      T +G ++   H+W Y +  HR ++R    ++  W  + +   +P+++   + I++A 
Sbjct:   26 RINSEKIYELRTYAIKPKDFIDYMRLTYDHIGLRTNHSKLCGFWATELGGLNQAVHIWEYDNFAHRTEVRKALSQDEKWQSQYMAKMMPMLQRQENLIMKAV 127

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Medaka
Match: nipsnap1 (nipsnap homolog 1 [Source:NCBI gene;Acc:101164564])

HSP 1 Score: 230.335 bits (586), Expect = 2.777e-74
Identity = 112/252 (44.44%), Postives = 169/252 (67.06%), Query Frame = 2

Query:   77 RCFSTGNDNKWFGNLFVRKLDSVHESQSDLLAK--SSTLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQS-GAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            R FS  +D  W  +LFV+K+D+  ++ S+LL+K  +S+LY+   H+VKP  +  Y +  A   + +   Q    E++GSW T  GEQD A HLWR++  +P L +  +  R++ ++ EFR+ R++ML  R+NQ+L  FS+W E  PR+  + I+ELR+Y LKPGTMIEWGN WAR I+ R+ ++E + G F+ +GD+++VHH+WAY+ L+ R++ RN AWR  GWD  V +TVPLIR M S I+  T+ SP+
Sbjct:   21 RRFSESSDKGWLRSLFVQKVDARKDAHSNLLSKKETSSLYKIQFHDVKPECLDAYNSLEAEVQKKLHQDQDFPCEVVGSWNTWYGEQDQAVHLWRYRGGYPALTECLQKLRANKEYLEFRRERSKMLISRRNQLLLEFSFWNEPLPRRGPN-IYELRTYKLKPGTMIEWGNRWARAIKYRQSNNEAVGGFFSQIGDLYVVHHLWAYESLQSREETRNSAWRKEGWDVNVYYTVPLIRSMESRIMIPTESSPL 271

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Medaka
Match: nipsnap2 (nipsnap homolog 2 [Source:NCBI gene;Acc:101168476])

HSP 1 Score: 229.18 bits (583), Expect = 7.970e-74
Identity = 118/260 (45.38%), Postives = 167/260 (64.23%), Query Frame = 2

Query:   77 RCFSTGN----DNKWFGNLFVRKLDSVHESQSDLLAKS--STLYEFHIHNVKPAYMSEYLADYARYNEMI-----KTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            RCF+  +    ++ WF +LFVRK+D   ++ ++LL K+  S LY+   HNVKP    E L  Y +  E +       K    EL+G+W T  GEQD A HLWR++  +P L +     R + +F  +RK R +ML  R+NQ+L  FS+W E  PR+  + I+ELRSY L+PGTMIEWGN+WARGIR R+++ E + G F+ +GD++MVHH+WAY+DL+ R++ RN AW   GW E V +TVPLI+HM S I+   K SP+
Sbjct:   15 RCFTASSHACSEDSWFKSLFVRKVDPRKDAHANLLTKNEESNLYKIQFHNVKP----ECLDAYNKLCEDVLPTIHADKYYPCELVGTWNTWYGEQDQAVHLWRYRGGYPALTEVMNKLRQNKEFTAYRKERGKMLLSRRNQLLLEFSFWNEPVPREGPN-IYELRSYQLRPGTMIEWGNYWARGIRHRQRNKEAVGGFFSQIGDLYMVHHLWAYEDLQSREETRNGAWHQEGWHEAVYYTVPLIQHMESRIMIPLKASPL 269

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Medaka
Match: nipsnap2 (nipsnap homolog 2 [Source:NCBI gene;Acc:101168476])

HSP 1 Score: 226.098 bits (575), Expect = 2.072e-72
Identity = 115/250 (46.00%), Postives = 163/250 (65.20%), Query Frame = 2

Query:   95 NDNKWFGNLFVRKLDSVHESQSDLLAKS--STLYEFHIHNVKPAYMSEYLADYARYNEMI-----KTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            +++ WF +LFVRK+D   ++ ++LL K+  S LY+   HNVKP    E L  Y +  E +       K    EL+G+W T  GEQD A HLWR++  +P L +     R + +F  +RK R +ML  R+NQ+L  FS+W E  PR+  + I+ELRSY L+PGTMIEWGN+WARGIR R+++ E + G F+ +GD++MVHH+WAY+DL+ R++ RN AW   GW E V +TVPLI+HM S I+   K SP+
Sbjct:   43 SEDSWFKSLFVRKVDPRKDAHANLLTKNEESNLYKIQFHNVKP----ECLDAYNKLCEDVLPTIHADKYYPCELVGTWNTWYGEQDQAVHLWRYRGGYPALTEVMNKLRQNKEFTAYRKERGKMLLSRRNQLLLEFSFWNEPVPREGPN-IYELRSYQLRPGTMIEWGNYWARGIRHRQRNKEAVGGFFSQIGDLYMVHHLWAYEDLQSREETRNGAWHQEGWHEAVYYTVPLIQHMESRIMIPLKASPL 287

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000003512.2 (protein NipSnap homolog 2 [Source:NCBI gene;Acc:101159691])

HSP 1 Score: 221.09 bits (562), Expect = 1.312e-70
Identity = 110/256 (42.97%), Postives = 160/256 (62.50%), Query Frame = 2

Query:   68 HFNRCFSTGNDNKWFGNLFVRKLDSVHESQSDLLAKS--STLYEFHIHNVKPAYMSEY--LADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKD-FPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            H N   +       F +LF+RK+D   ++ S++L+K     LY+   HNVKP  +  Y  L + A    +    +  +EL+G+W T  GEQD A HLWR++  +P L +     + + +F E+RK R +ML  R+NQ+L  FS+W E  PR   + I+ELRSY L+PGTMIEWGN+WAR I +R+++ E + G F+ +G ++ VHH+WAYKDL+ R + RN AW+  GWDE V +TVPLI+HM S I+   K SP+
Sbjct:   21 HINGAVTITRSLSGFKSLFIRKVDPRKDAHSNVLSKKEEQNLYKIQFHNVKPECLDAYNELCE-AVLPSIHANPEYPSELVGTWNTWYGEQDQAVHLWRYRGGYPALTEVMNKLKQNKEFMEYRKERGKMLLSRRNQLLLEFSFWNEPVPRPGPN-IYELRSYQLRPGTMIEWGNYWARAIEIRQKNQEAVGGFFSQIGSLYTVHHLWAYKDLQSRDETRNAAWQQEGWDEVVYYTVPLIQHMESRIMIPMKSSPL 274

[Close]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Medaka
Match: nipsnap3a (protein NipSnap homolog 3A [Source:NCBI gene;Acc:101171648])

HSP 1 Score: 71.633 bits (174), Expect = 3.209e-14
Identity = 47/216 (21.76%), Postives = 99/216 (45.83%), Query Frame = 2

Query:  182 TLYEFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKDFPILDKHYRLYRSDAD-FEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQ--HSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPI 820
            T YEF  +++ P   + +L      NE I  + + +EL+G WT E G  +  +H+W++  +            D     ++  +   ML  + N++ +    W  +  +   + ++EL SY ++PG    WG+ +   I  R    + + +    +  G ++ VH +W Y+  +HR ++R++A  +      V ++V  +    + ++    FSP+
Sbjct:   30 TFYEFRTYSIHPHQNAAFLK---LTNEKIHLRTAHSELIGYWTVEYGGLNQVFHIWKYDSYSQRAAVRAALAQDPTWISDYISKALPMLTSQDNEVTY-LVPWSRLH-KPPKEGVYELASYQMRPGGPAVWGSAFQAAICARDAPGYGKLLGAFHSEFGALNQVHALWWYESADHRAEVRHKAHNDARVVAAVRNSVTHLDTQRNRLMHPCLFSPM 240

[Close]

BLAST of NIPSNAP domain-containing protein vs. Planmine SMEST
Match: SMESG000043687.1 (SMESG000043687.1)

HSP 1 Score: 423.705 bits (1088), Expect = 1.149e-151
Identity = 200/200 (100.00%), Postives = 200/200 (100.00%), Query Frame = 2

Query:  224 MSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKDFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPIY 823
            MSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKDFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPIY
Sbjct:    1 MSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAYHLWRFKDFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWPEIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATKFSPIY 200

The following BLAST results are available for this feature:

BLAST of NIPSNAP domain-containing protein vs. Ensembl Human
BLAST of NIPSNAP domain-containing protein vs. Ensembl Celegans
BLAST of NIPSNAP domain-containing protein vs. Ensembl Fly
BLAST of NIPSNAP domain-containing protein vs. Ensembl Zebrafish
BLAST of NIPSNAP domain-containing protein vs. Ensembl Xenopus
BLAST of NIPSNAP domain-containing protein vs. Ensembl Mouse
BLAST of NIPSNAP domain-containing protein vs. UniProt/SwissProt
BLAST of NIPSNAP domain-containing protein vs. TrEMBL
BLAST of NIPSNAP domain-containing protein vs. Ensembl Cavefish
BLAST of NIPSNAP domain-containing protein vs. Ensembl Sea Lamprey
BLAST of NIPSNAP domain-containing protein vs. Ensembl Yeast
BLAST of NIPSNAP domain-containing protein vs. Ensembl Nematostella
BLAST of NIPSNAP domain-containing protein vs. Ensembl Medaka
BLAST of NIPSNAP domain-containing protein vs. Planmine SMEST

BLAST of NIPSNAP domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NIPSNAP1	5.179e-75	46.09	nipsnap homolog 1 [Source:HGNC Symbol;Acc:HGNC:782...	[more]
NIPSNAP2	3.385e-71	46.53	nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:417...	[more]
NIPSNAP2	1.206e-51	39.92	nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:417...	[more]
NIPSNAP1	9.940e-39	44.00	nipsnap homolog 1 [Source:HGNC Symbol;Acc:HGNC:782...	[more]
NIPSNAP2	1.194e-27	51.92	nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:417...	[more]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
K02D10.1	9.997e-53	38.50	Putative NipSnap protein K02D10.1 [Source:UniProt...	[more]
K02D10.1	9.997e-53	38.50	Putative NipSnap protein K02D10.1 [Source:UniProt...	[more]
K02D10.1	1.831e-50	38.84	Putative NipSnap protein K02D10.1 [Source:UniProt...	[more]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Nipsnap	3.517e-72	42.01	gene:FBgn0030724 transcript:FBtr0074259	[more]
Nipsnap	3.517e-72	42.01	gene:FBgn0030724 transcript:FBtr0343595	[more]
Nipsnap	3.517e-72	42.01	gene:FBgn0030724 transcript:FBtr0074257	[more]
Nipsnap	3.517e-72	42.01	gene:FBgn0030724 transcript:FBtr0074258	[more]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
nipsnap1	3.531e-72	45.06	nipsnap homolog 1 (C. elegans) [Source:NCBI gene;A...	[more]
nipsnap2	1.302e-48	42.01	pep chromosome:GRCz11:15:404891:413541:1 gene:ENSD...	[more]
nipsnap3a	3.147e-14	21.76	nipsnap homolog 3A (C. elegans) [Source:ZFIN;Acc:Z...	[more]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nipsnap2	1.864e-75	47.64	nipsnap homolog 2 [Source:NCBI gene;Acc:733910]	[more]
nipsnap2	9.221e-75	47.81	nipsnap homolog 2 [Source:NCBI gene;Acc:733910]	[more]
mgat2	5.104e-71	44.96	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acet...	[more]
mgat2	3.332e-70	45.06	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acet...	[more]
mgat2	3.377e-70	44.92	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acet...	[more]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Nipsnap1	1.105e-73	45.70	nipsnap homolog 1 [Source:MGI Symbol;Acc:MGI:12783...	[more]
Nipsnap2	2.173e-71	46.12	nipsnap homolog 2 [Source:MGI Symbol;Acc:MGI:12783...	[more]
Nipsnap2	2.173e-71	46.12	nipsnap homolog 2 [Source:MGI Symbol;Acc:MGI:12783...	[more]
Nipsnap2	2.173e-71	46.12	nipsnap homolog 2 [Source:MGI Symbol;Acc:MGI:12783...	[more]
Nipsnap1	5.186e-15	36.22	nipsnap homolog 1 [Source:MGI Symbol;Acc:MGI:12783...	[more]

BLAST of NIPSNAP domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9BPW8\|NIPS1_HUMAN	2.487e-74	46.09	Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 ...	[more]
sp\|O55125\|NIPS1_MOUSE	7.730e-73	45.70	Protein NipSnap homolog 1 OS=Mus musculus OX=10090...	[more]
sp\|Q9VXK0\|NIPSN_DROME	3.526e-71	42.01	Protein NipSnap OS=Drosophila melanogaster OX=7227...	[more]
sp\|Q9PU58\|NIPS2_DANRE	3.977e-71	46.59	Protein NipSnap homolog 2 OS=Danio rerio OX=7955 G...	[more]
sp\|O75323\|NIPS2_HUMAN	1.625e-70	46.53	Protein NipSnap homolog 2 OS=Homo sapiens OX=9606 ...	[more]

BLAST of NIPSNAP domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4S2LSE9	2.189e-90	51.97	NIPSNAP domain-containing protein OS=Opisthorchis ...	[more]
A0A074YZ70	2.362e-90	51.57	NIPSNAP domain-containing protein OS=Opisthorchis ...	[more]
R7TLM6	3.530e-88	52.50	Uncharacterized protein OS=Capitella teleta OX=283...	[more]
A0A1S3H692	1.050e-87	49.24	protein NipSnap-like isoform X1 OS=Lingula unguis ...	[more]
A0A1S3JJF0	1.134e-87	49.24	protein NipSnap-like OS=Lingula unguis OX=7574 GN=...	[more]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000034199.1	9.833e-76	47.39	protein NipSnap homolog 2 [Source:NCBI gene;Acc:10...	[more]
nipsnap2	3.907e-72	46.59	nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:417...	[more]
nipsnap1	7.675e-70	43.31	protein NipSnap homolog 1-like [Source:NCBI gene;A...	[more]
nipsnap1	3.101e-69	43.60	protein NipSnap homolog 1-like [Source:NCBI gene;A...	[more]
nipsnap1	3.333e-61	41.88	protein NipSnap homolog 1-like [Source:NCBI gene;A...	[more]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
nipsnap2	3.629e-77	45.17	nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:417...	[more]
nipsnap3a	6.500e-9	19.53	nipsnap homolog 3A (C. elegans) [Source:ZFIN;Acc:Z...	[more]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of NIPSNAP domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO40732	6.325e-29	29.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of NIPSNAP domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nipsnap1	2.777e-74	44.44	nipsnap homolog 1 [Source:NCBI gene;Acc:101164564]	[more]
nipsnap2	7.970e-74	45.38	nipsnap homolog 2 [Source:NCBI gene;Acc:101168476]	[more]
nipsnap2	2.072e-72	46.00	nipsnap homolog 2 [Source:NCBI gene;Acc:101168476]	[more]
ENSORLT00000003512.2	1.312e-70	42.97	protein NipSnap homolog 2 [Source:NCBI gene;Acc:10...	[more]
nipsnap3a	3.209e-14	21.76	protein NipSnap homolog 3A [Source:NCBI gene;Acc:1...	[more]

BLAST of NIPSNAP domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000043687.1	1.149e-151	100.00	SMESG000043687.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30004082 ID=SMED30004082|Name=NIPSNAP domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=950bp
AATATTAACAGAAAAAAATAATTTATAAATTTTACGTTAAATGTTCAAAT
TTATAAGATTACGCAATCATTTTAATCGTTGTTTTTCAACTGGAAACGAT
AATAAATGGTTTGGAAATCTTTTTGTTCGTAAACTAGATTCCGTTCATGA
ATCTCAATCGGATCTCTTAGCTAAAAGTAGTACACTATATGAATTTCATA
TTCATAACGTAAAACCGGCTTATATGAGTGAATATTTAGCAGATTATGCA
CGTTACAATGAAATGATTAAAACGAAACAAAGTGGCGCCGAATTAATGGG
CAGTTGGACAACTGAAATTGGAGAACAGGATACTGCTTATCATTTGTGGC
GTTTTAAAGATTTCCCTATTTTGGATAAGCATTATAGACTCTATAGATCT
GATGCGGATTTTGAAGAATTTCGTAAACGAAGAAATGAAATGCTTTATTT
CCGTAAGAATCAGATTCTATTCCCATTCAGTTATTGGCCGGAAATTCAAC
CCAGACAATCAGATGATTCGATATTTGAATTACGCTCTTACACTCTTAAG
CCGGGTACAATGATCGAATGGGGTAATCATTGGGCACGAGGAATTAGAGT
ACGTAAACAGCATTCTGAACCGATTGCTGGCTTGTTTACTCATGTCGGGG
ATATCCACATGGTTCATCATATGTGGGCTTACAAAGATCTGGAACATCGA
AAGAAAATGAGAAACGAAGCTTGGAGAAATCCTGGATGGGATGAATGTGT
TCTTCATACGGTCCCTTTGATTCGTCATATGAATAGCAACATCCTGAGAG
CGACAAAATTCAGCCCAATCTATTAAGGAATCGCAAATGGAAATTTAAAG
TCCAACTTTTAAAAATAAAATTAGATAAAATATTTAATGAATTTTTTTGC
TAAGTTTTCTCATTTTAAGTAGAATCGTATTGATTGTGATCATTTCTTAA

protein sequence of SMED30004082-orf-1

>SMED30004082-orf-1 ID=SMED30004082-orf-1|Name=SMED30004082-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=262bp
MFKFIRLRNHFNRCFSTGNDNKWFGNLFVRKLDSVHESQSDLLAKSSTLY
EFHIHNVKPAYMSEYLADYARYNEMIKTKQSGAELMGSWTTEIGEQDTAY
HLWRFKDFPILDKHYRLYRSDADFEEFRKRRNEMLYFRKNQILFPFSYWP
EIQPRQSDDSIFELRSYTLKPGTMIEWGNHWARGIRVRKQHSEPIAGLFT
HVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSN
ILRATKFSPIY*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0097060	synaptic membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000418	head
PLANA:0000429	neoblast

Vocabulary: **INTERPRO**
Term	Definition
IPR012577	NIPSNAP
IPR011008	Dimeric_a/b-barrel

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0042165	neurotransmitter binding

Vocabulary: **biological process**
Term	Definition
GO:0019233	sensory perception of pain

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR012577	NIPSNAP	PFAM	PF07978	NIPSNAP	coord: 50..148 e-value: 2.8E-10 score: 40.3 coord: 162..259 e-value: 3.6E-28 score: 97.8
None	No IPR available	GENE3D	G3DSA:3.30.70.100		coord: 158..261 e-value: 1.3E-35 score: 123.9 coord: 43..157 e-value: 5.2E-21 score: 76.7
None	No IPR available	PANTHER	PTHR21017:SF17	PROTEIN NIPSNAP	coord: 24..260
None	No IPR available	PANTHER	PTHR21017	NIPSNAP-RELATED	coord: 24..260
IPR011008	Dimeric alpha-beta barrel	SUPERFAMILY	SSF54909	Dimeric alpha+beta barrel	coord: 156..260
IPR011008	Dimeric alpha-beta barrel	SUPERFAMILY	SSF54909	Dimeric alpha+beta barrel	coord: 44..150

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NIPSNAP domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Owlery

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