Cyclin-dependent kinase 16

Overview
NameCyclin-dependent kinase 16
Smed IDSMED30004031
Length (bp)2069
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cyclin-dependent kinase 16 (SMED30004031) t-SNE clustered cells

Violin plots show distribution of expression levels for Cyclin-dependent kinase 16 (SMED30004031) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cyclin-dependent kinase 16 (SMED30004031) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cyclin-dependent kinase 16 (SMED30004031) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30004031

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30004031h1SMcG0022320 Contig8734uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30004031h1SMcG0022320 Contig8734newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30004031h1SMcG0022320 Contig40843newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Human
Match: CDK17 (cyclin dependent kinase 17 [Source:HGNC Symbol;Acc:HGNC:8750])

HSP 1 Score: 504.597 bits (1298), Expect = 1.872e-172
Identity = 251/371 (67.65%), Postives = 302/371 (81.40%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATV+KGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMSM+NV++FLYQILRGLAYCHRR++LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG PS+ TWPGISSN+EF +  F     PQ L N  PRL   G+ L+T  L+Y+ KKR+SAE+AM+H YF RS  P   +  L ++ S+F +  + L  DPG
Sbjct:  137 SMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNF-PKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF-RSLGP--RIHALPESVSIFSLKEIQLQKDPG 502          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Human
Match: CDK17 (cyclin dependent kinase 17 [Source:HGNC Symbol;Acc:HGNC:8750])

HSP 1 Score: 502.286 bits (1292), Expect = 2.402e-172
Identity = 251/371 (67.65%), Postives = 302/371 (81.40%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATV+KGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMSM+NV++FLYQILRGLAYCHRR++LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG PS+ TWPGISSN+EF +  F     PQ L N  PRL   G+ L+T  L+Y+ KKR+SAE+AM+H YF RS  P   +  L ++ S+F +  + L  DPG
Sbjct:   84 SMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNF-PKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF-RSLGP--RIHALPESVSIFSLKEIQLQKDPG 449          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Human
Match: CDK17 (cyclin dependent kinase 17 [Source:HGNC Symbol;Acc:HGNC:8750])

HSP 1 Score: 504.212 bits (1297), Expect = 3.399e-172
Identity = 251/371 (67.65%), Postives = 302/371 (81.40%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATV+KGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMSM+NV++FLYQILRGLAYCHRR++LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG PS+ TWPGISSN+EF +  F     PQ L N  PRL   G+ L+T  L+Y+ KKR+SAE+AM+H YF RS  P   +  L ++ S+F +  + L  DPG
Sbjct:  137 SMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNF-PKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF-RSLGP--RIHALPESVSIFSLKEIQLQKDPG 502          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Human
Match: CDK16 (cyclin dependent kinase 16 [Source:HGNC Symbol;Acc:HGNC:8749])

HSP 1 Score: 499.975 bits (1286), Expect = 8.718e-172
Identity = 240/366 (65.57%), Postives = 300/366 (81.97%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR---KSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHL 1889
            S  D +KRLSLPA+I LP   L +    S + + P++++ RR SL+EIGFGKLE+Y KLDKLG+GTYATV+KG+S+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT KSLTLVFEYL KDLKQY++DC NI++M+NV++FL+Q+LRGLAYCHR+++LHRDLKPQNLLIN  RG+LKLADFGLARAKSIP KTYSNEVVTLWYRPPD+LLGST+YSTQIDMWGVGCI +EMA GRP+FPGSTV+E+L  IF+ LG P+E TWPGI SN+EF +  +    + ++L +  PRL   G  LLT LL+++G+ RISAEDAM+H +F+      E + +L DT S+F +  + L
Sbjct:   62 STEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINE-RGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRA-EALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLG---ERIHKLPDTTSIFALKEIQL 422          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Human
Match: CDK16 (cyclin dependent kinase 16 [Source:HGNC Symbol;Acc:HGNC:8749])

HSP 1 Score: 500.36 bits (1287), Expect = 3.479e-171
Identity = 240/366 (65.57%), Postives = 300/366 (81.97%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR---KSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHL 1889
            S  D +KRLSLPA+I LP   L +    S + + P++++ RR SL+EIGFGKLE+Y KLDKLG+GTYATV+KG+S+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT KSLTLVFEYL KDLKQY++DC NI++M+NV++FL+Q+LRGLAYCHR+++LHRDLKPQNLLIN  RG+LKLADFGLARAKSIP KTYSNEVVTLWYRPPD+LLGST+YSTQIDMWGVGCI +EMA GRP+FPGSTV+E+L  IF+ LG P+E TWPGI SN+EF +  +    + ++L +  PRL   G  LLT LL+++G+ RISAEDAM+H +F+      E + +L DT S+F +  + L
Sbjct:  110 STEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINE-RGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRA-EALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLG---ERIHKLPDTTSIFALKEIQL 470          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Celegans
Match: pct-1 (Cyclin-dependent kinase 17 [Source:UniProtKB/Swiss-Prot;Acc:Q8I7M8])

HSP 1 Score: 460.685 bits (1184), Expect = 5.813e-155
Identity = 231/368 (62.77%), Postives = 278/368 (75.54%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHL---LNRKSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEF---TSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHL 1889
            SE +  KRLSLPA++ LP  +   LNR   L +P+T+K+RR SL+EIGFGKLE+Y KLDKLG+GTYATVF+GRS LT   VALKEIRLE EEGAPCTAIREVSLLRNL HANVVTLHDIIHT + LTLVFEY+ +DLKQYM+ C N M MNN+++FLYQ+LRGLAYCH+RR+LHRDLKPQNLLI   +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST+YST IDMWGVGCILFEM AGR +FPG T  E+L LIF+TLG P     P I     F    +R +N    P  L   +PR+   G  LL   L+Y+GK R+SA +A++H +    ++ V+    L+D  SV +  G+H+
Sbjct:  184 SEEEIQKRLSLPADLRLPVAVVDKLNRTPTLDQPLTRKNRRASLSEIGFGKLETYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLIT-AKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYN----PDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL--RTIAVKC-CHLRDEQSVLEADGIHI 543          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Celegans
Match: pct-1 (Cyclin-dependent kinase 17 [Source:UniProtKB/Swiss-Prot;Acc:Q8I7M8])

HSP 1 Score: 462.996 bits (1190), Expect = 1.463e-154
Identity = 231/368 (62.77%), Postives = 278/368 (75.54%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHL---LNRKSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEF---TSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHL 1889
            SE +  KRLSLPA++ LP  +   LNR   L +P+T+K+RR SL+EIGFGKLE+Y KLDKLG+GTYATVF+GRS LT   VALKEIRLE EEGAPCTAIREVSLLRNL HANVVTLHDIIHT + LTLVFEY+ +DLKQYM+ C N M MNN+++FLYQ+LRGLAYCH+RR+LHRDLKPQNLLI   +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST+YST IDMWGVGCILFEM AGR +FPG T  E+L LIF+TLG P     P I     F    +R +N    P  L   +PR+   G  LL   L+Y+GK R+SA +A++H +    ++ V+    L+D  SV +  G+H+
Sbjct:  274 SEEEIQKRLSLPADLRLPVAVVDKLNRTPTLDQPLTRKNRRASLSEIGFGKLETYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLIT-AKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYN----PDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL--RTIAVKC-CHLRDEQSVLEADGIHI 633          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Celegans
Match: pct-1 (Cyclin-dependent kinase 17 [Source:UniProtKB/Swiss-Prot;Acc:Q8I7M8])

HSP 1 Score: 462.996 bits (1190), Expect = 1.463e-154
Identity = 231/368 (62.77%), Postives = 278/368 (75.54%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHL---LNRKSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEF---TSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHL 1889
            SE +  KRLSLPA++ LP  +   LNR   L +P+T+K+RR SL+EIGFGKLE+Y KLDKLG+GTYATVF+GRS LT   VALKEIRLE EEGAPCTAIREVSLLRNL HANVVTLHDIIHT + LTLVFEY+ +DLKQYM+ C N M MNN+++FLYQ+LRGLAYCH+RR+LHRDLKPQNLLI   +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST+YST IDMWGVGCILFEM AGR +FPG T  E+L LIF+TLG P     P I     F    +R +N    P  L   +PR+   G  LL   L+Y+GK R+SA +A++H +    ++ V+    L+D  SV +  G+H+
Sbjct:  274 SEEEIQKRLSLPADLRLPVAVVDKLNRTPTLDQPLTRKNRRASLSEIGFGKLETYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLIT-AKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYN----PDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL--RTIAVKC-CHLRDEQSVLEADGIHI 633          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Celegans
Match: pct-1 (Cyclin-dependent kinase 17 [Source:UniProtKB/Swiss-Prot;Acc:Q8I7M8])

HSP 1 Score: 462.996 bits (1190), Expect = 1.463e-154
Identity = 231/368 (62.77%), Postives = 278/368 (75.54%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHL---LNRKSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEF---TSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHL 1889
            SE +  KRLSLPA++ LP  +   LNR   L +P+T+K+RR SL+EIGFGKLE+Y KLDKLG+GTYATVF+GRS LT   VALKEIRLE EEGAPCTAIREVSLLRNL HANVVTLHDIIHT + LTLVFEY+ +DLKQYM+ C N M MNN+++FLYQ+LRGLAYCH+RR+LHRDLKPQNLLI   +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST+YST IDMWGVGCILFEM AGR +FPG T  E+L LIF+TLG P     P I     F    +R +N    P  L   +PR+   G  LL   L+Y+GK R+SA +A++H +    ++ V+    L+D  SV +  G+H+
Sbjct:  274 SEEEIQKRLSLPADLRLPVAVVDKLNRTPTLDQPLTRKNRRASLSEIGFGKLETYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLIT-AKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYN----PDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL--RTIAVKC-CHLRDEQSVLEADGIHI 633          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Celegans
Match: cdk-5 (Cyclin-dependent-like kinase 5 [Source:UniProtKB/Swiss-Prot;Acc:G5ECH7])

HSP 1 Score: 287.345 bits (734), Expect = 1.123e-91
Identity = 140/291 (48.11%), Postives = 194/291 (66.67%), Query Frame = 3
Query:  954 SYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHE-EGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMA-AGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSS 1820
            +Y K++K+G+GTY TVFK R++ +  +VALK +RL+ + EG P +A+RE+ +LR L H NVV L+D++H+   LTLVFEY  +DLK++ +     M     +  + Q+LRGL++CH   +LHRDLKPQNLLIN   G LKLADFGLARA  +P++ +S EVVTLWYRPPDVL G+  Y+T IDMW  GCI  E++ AGRP+FPG+ VD++L+ IFK LG PSE  WP I+   ++  + +       +   +VP L   G  LL  LL      RI A+ A++H YF  +S
Sbjct:    3 NYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVRLYDVVHSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLKPQNLLIN-TNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDY--KPYPIYHPTLTWSQIVPNLNSRGRDLLQKLLVCNPAGRIDADAALRHAYFADTS 290          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Fly
Match: Eip63E (gene:FBgn0005640 transcript:FBtr0110922)

HSP 1 Score: 360.533 bits (924), Expect = 6.719e-117
Identity = 186/338 (55.03%), Postives = 236/338 (69.82%), Query Frame = 3
Query:  912 RRYSLAEIG----FGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPG--STVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQ--FTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDP 1901
            RR   +  G    FGK E+Y KL+ LG+G+YATV+KG S+LT   VALKEIRL+ EEGAP TAIRE SLL+ L H+N+VTLHDI+HT ++LT VFEY++ DL QYME     +   NV++FL+Q+LRGL+YCH+RR+LHRD+KPQNLLI+   G+LKLADFGLARAKS+P  TYS+EVVTLWYRPPDVLLGST YST +DMWGVGCI  EM  G P FPG   T D +L  IFK LG P+E TWPG++    +   +      P+ L +  PRL     G ++  G L+   ++R+ A+DA+QH YF  + LP + L  L D  S+F V GV L  +P
Sbjct:  165 RRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDC-GELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYD-QLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYR-PRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYF--AQLP-KKLYELPDETSIFTVEGVQLYTEP 496          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Fly
Match: Eip63E (gene:FBgn0005640 transcript:FBtr0073134)

HSP 1 Score: 360.533 bits (924), Expect = 8.226e-117
Identity = 186/338 (55.03%), Postives = 236/338 (69.82%), Query Frame = 3
Query:  912 RRYSLAEIG----FGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPG--STVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQ--FTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDP 1901
            RR   +  G    FGK E+Y KL+ LG+G+YATV+KG S+LT   VALKEIRL+ EEGAP TAIRE SLL+ L H+N+VTLHDI+HT ++LT VFEY++ DL QYME     +   NV++FL+Q+LRGL+YCH+RR+LHRD+KPQNLLI+   G+LKLADFGLARAKS+P  TYS+EVVTLWYRPPDVLLGST YST +DMWGVGCI  EM  G P FPG   T D +L  IFK LG P+E TWPG++    +   +      P+ L +  PRL     G ++  G L+   ++R+ A+DA+QH YF  + LP + L  L D  S+F V GV L  +P
Sbjct:  173 RRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDC-GELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYD-QLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYR-PRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYF--AQLP-KKLYELPDETSIFTVEGVQLYTEP 504          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Fly
Match: Eip63E (gene:FBgn0005640 transcript:FBtr0073133)

HSP 1 Score: 360.533 bits (924), Expect = 8.226e-117
Identity = 186/338 (55.03%), Postives = 236/338 (69.82%), Query Frame = 3
Query:  912 RRYSLAEIG----FGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPG--STVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQ--FTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDP 1901
            RR   +  G    FGK E+Y KL+ LG+G+YATV+KG S+LT   VALKEIRL+ EEGAP TAIRE SLL+ L H+N+VTLHDI+HT ++LT VFEY++ DL QYME     +   NV++FL+Q+LRGL+YCH+RR+LHRD+KPQNLLI+   G+LKLADFGLARAKS+P  TYS+EVVTLWYRPPDVLLGST YST +DMWGVGCI  EM  G P FPG   T D +L  IFK LG P+E TWPG++    +   +      P+ L +  PRL     G ++  G L+   ++R+ A+DA+QH YF  + LP + L  L D  S+F V GV L  +P
Sbjct:  173 RRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDC-GELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYD-QLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYR-PRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYF--AQLP-KKLYELPDETSIFTVEGVQLYTEP 504          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Fly
Match: Eip63E (gene:FBgn0005640 transcript:FBtr0073135)

HSP 1 Score: 360.533 bits (924), Expect = 8.226e-117
Identity = 186/338 (55.03%), Postives = 236/338 (69.82%), Query Frame = 3
Query:  912 RRYSLAEIG----FGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPG--STVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQ--FTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDP 1901
            RR   +  G    FGK E+Y KL+ LG+G+YATV+KG S+LT   VALKEIRL+ EEGAP TAIRE SLL+ L H+N+VTLHDI+HT ++LT VFEY++ DL QYME     +   NV++FL+Q+LRGL+YCH+RR+LHRD+KPQNLLI+   G+LKLADFGLARAKS+P  TYS+EVVTLWYRPPDVLLGST YST +DMWGVGCI  EM  G P FPG   T D +L  IFK LG P+E TWPG++    +   +      P+ L +  PRL     G ++  G L+   ++R+ A+DA+QH YF  + LP + L  L D  S+F V GV L  +P
Sbjct:  173 RRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDC-GELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYD-QLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYR-PRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYF--AQLP-KKLYELPDETSIFTVEGVQLYTEP 504          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Fly
Match: Eip63E (gene:FBgn0005640 transcript:FBtr0110924)

HSP 1 Score: 360.533 bits (924), Expect = 8.226e-117
Identity = 186/338 (55.03%), Postives = 236/338 (69.82%), Query Frame = 3
Query:  912 RRYSLAEIG----FGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPG--STVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQ--FTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDP 1901
            RR   +  G    FGK E+Y KL+ LG+G+YATV+KG S+LT   VALKEIRL+ EEGAP TAIRE SLL+ L H+N+VTLHDI+HT ++LT VFEY++ DL QYME     +   NV++FL+Q+LRGL+YCH+RR+LHRD+KPQNLLI+   G+LKLADFGLARAKS+P  TYS+EVVTLWYRPPDVLLGST YST +DMWGVGCI  EM  G P FPG   T D +L  IFK LG P+E TWPG++    +   +      P+ L +  PRL     G ++  G L+   ++R+ A+DA+QH YF  + LP + L  L D  S+F V GV L  +P
Sbjct:  173 RRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDC-GELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYD-QLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYR-PRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYF--AQLP-KKLYELPDETSIFTVEGVQLYTEP 504          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Zebrafish
Match: cdk16 (cyclin-dependent kinase 16 [Source:ZFIN;Acc:ZDB-GENE-030131-2939])

HSP 1 Score: 502.671 bits (1293), Expect = 1.333e-172
Identity = 249/375 (66.40%), Postives = 300/375 (80.00%), Query Frame = 3
Query:  792 GIDSSESDASKRLSLPANINLPPHLLNR---KSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            G   S  D +KRLSLPA+I LP   L +    S L + P++++ RR SL+EIGFGKLE+Y KLDKLG+GTYATV+KGRS+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT KSLTLVFEYL KDLKQY++DC N + M+NV++FL+Q+LRGL YCHRR++LHRDLKPQNLLIN  RG+LKLADFGLARAKSIP KTYSNEVVTLWYRPPD+LLGST+YSTQIDMWGVGCI +EM+ GRP+FPGSTV+EEL  IFK LG P+E TWPGI+SN+EF S  +    +   L N  PRL   GV LL+ LL+++GKKRI+AE+AM+H YF       E L  L DT S+F +  + L  +PG
Sbjct:   79 GRKISTEDINKRLSLPADIRLPDGYLEKFSLNSPLFDKPLSRRLRRVSLSEIGFGKLETYVKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTQKSLTLVFEYLDKDLKQYLDDCGNSIHMHNVKLFLFQLLRGLNYCHRRKVLHRDLKPQNLLIND-RGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMSTGRPLFPGSTVEEELHFIFKLLGTPTEETWPGITSNEEFISYNYPRYRA-DCLHNHTPRLDNDGVELLSKLLQFEGKKRIAAEEAMRHPYF---HCLGERLLTLPDTTSIFALQEIQLEKEPG 448          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Zebrafish
Match: cdk16 (cyclin-dependent kinase 16 [Source:ZFIN;Acc:ZDB-GENE-030131-2939])

HSP 1 Score: 503.827 bits (1296), Expect = 2.440e-172
Identity = 248/371 (66.85%), Postives = 299/371 (80.59%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR---KSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I LP   L +    S L + P++++ RR SL+EIGFGKLE+Y KLDKLG+GTYATV+KGRS+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT KSLTLVFEYL KDLKQY++DC N + M+NV++FL+Q+LRGL YCHRR++LHRDLKPQNLLIN  RG+LKLADFGLARAKSIP KTYSNEVVTLWYRPPD+LLGST+YSTQIDMWGVGCI +EM+ GRP+FPGSTV+EEL  IFK LG P+E TWPGI+SN+EF S  +    +   L N  PRL   GV LL+ LL+++GKKRI+AE+AM+H YF       E L  L DT S+F +  + L  +PG
Sbjct:  138 STEDINKRLSLPADIRLPDGYLEKFSLNSPLFDKPLSRRLRRVSLSEIGFGKLETYVKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTQKSLTLVFEYLDKDLKQYLDDCGNSIHMHNVKLFLFQLLRGLNYCHRRKVLHRDLKPQNLLIND-RGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMSTGRPLFPGSTVEEELHFIFKLLGTPTEETWPGITSNEEFISYNYPRYRA-DCLHNHTPRLDNDGVELLSKLLQFEGKKRIAAEEAMRHPYF---HCLGERLLTLPDTTSIFALQEIQLEKEPG 503          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Zebrafish
Match: CDK18 (si:dkey-166c18.1 [Source:ZFIN;Acc:ZDB-GENE-141215-51])

HSP 1 Score: 501.516 bits (1290), Expect = 2.809e-172
Identity = 248/377 (65.78%), Postives = 301/377 (79.84%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNRKSQL-----LEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTV 1919
            S  D +KR+SLP +I LPP  L +K Q+      +P+++  RR SL++IGFGKLE+Y KL KLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL+NL HAN+VTLHDIIHT + LTLVFEYL  DLKQY+++C N+MSM+NV+IF++Q+LRGL+YCH+R+ILHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCIL+EMA GRPMFPGSTV EEL LIF+ +G P+E +WPGI++N+EF S  F    + Q+L N VPRL   G+ LLT LL Y  K+RISAE +++H YF   +L    LS + DT SVF +  + L  DPG   +V
Sbjct:   80 SMEDVTKRMSLPMDIRLPPEFL-KKLQMESPPPCKPLSRMSRRASLSDIGFGKLETYVKLGKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTDRCLTLVFEYLDSDLKQYLDNCGNLMSMHNVKIFMFQLLRGLSYCHKRKILHRDLKPQNLLIND-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGRPMFPGSTVKEELHLIFRLMGTPTEESWPGITANEEFKSYLFPQYRA-QALINHVPRLDTEGIDLLTALLLYDTKRRISAELSLRHSYF--QTLGENILS-IPDTSSVFSLREIQLQKDPGHRSSV 450          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Zebrafish
Match: CDK18 (si:dkey-166c18.1 [Source:ZFIN;Acc:ZDB-GENE-141215-51])

HSP 1 Score: 501.516 bits (1290), Expect = 2.809e-172
Identity = 248/377 (65.78%), Postives = 301/377 (79.84%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNRKSQL-----LEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTV 1919
            S  D +KR+SLP +I LPP  L +K Q+      +P+++  RR SL++IGFGKLE+Y KL KLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL+NL HAN+VTLHDIIHT + LTLVFEYL  DLKQY+++C N+MSM+NV+IF++Q+LRGL+YCH+R+ILHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCIL+EMA GRPMFPGSTV EEL LIF+ +G P+E +WPGI++N+EF S  F    + Q+L N VPRL   G+ LLT LL Y  K+RISAE +++H YF   +L    LS + DT SVF +  + L  DPG   +V
Sbjct:   80 SMEDVTKRMSLPMDIRLPPEFL-KKLQMESPPPCKPLSRMSRRASLSDIGFGKLETYVKLGKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTDRCLTLVFEYLDSDLKQYLDNCGNLMSMHNVKIFMFQLLRGLSYCHKRKILHRDLKPQNLLIND-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGRPMFPGSTVKEELHLIFRLMGTPTEESWPGITANEEFKSYLFPQYRA-QALINHVPRLDTEGIDLLTALLLYDTKRRISAELSLRHSYF--QTLGENILS-IPDTSSVFSLREIQLQKDPGHRSSV 450          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Zebrafish
Match: cdk17 (cyclin-dependent kinase 17 [Source:ZFIN;Acc:ZDB-GENE-041210-15])

HSP 1 Score: 498.049 bits (1281), Expect = 4.703e-170
Identity = 256/399 (64.16%), Postives = 306/399 (76.69%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLXXXXXXXNQKKRPQSVIY 1988
            S  D +KRLSLPA+I +P   L +         +P++++ RR SL+EIGFGKLE+Y KLDKLG+GTYATVFKGRS+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMSM+NV+IFL+QILRGLAYCHRR++LHRDLKPQNLLIN  RG+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI +EMAAGRP+FPGSTV++EL LIF+ LG P+E  WPGISS +EF S  F     PQ   N  PRL   G+ LL   L Y+ KKRISA+++M+H YF    + +  L    ++ S+F +  V L  DPG        R SS     N K R QS+++
Sbjct:  140 SMEDLNKRLSLPADIRIPDGYLEKLQLSSPPFDQPLSRRSRRASLSEIGFGKLETYIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKIFLFQILRGLAYCHRRKVLHRDLKPQNLLINE-RGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFYEMAAGRPLFPGSTVEDELHLIFRLLGTPTEDNWPGISSIEEFKSYNF-PKYKPQPFINHAPRLDTEGIELLLSFLRYESKKRISADESMKHSYFKSLGMRIHTLP---ESISIFTLKEVQLQRDPG-------YRNSSYPETGNSKNRRQSMLF 526          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Xenopus
Match: ambn (ameloblastin [Source:Xenbase;Acc:XB-GENE-853786])

HSP 1 Score: 506.908 bits (1304), Expect = 3.821e-174
Identity = 266/440 (60.45%), Postives = 318/440 (72.27%), Query Frame = 3
Query:  621 EEEAKDRFVVIEKGKCYVDGELVQG--------LSPSQLAQVRRRHRRPXXXXXXXXXXXXXXERGIDSSESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            E  +KD  +V E  K   DGE  Q          SP+ +    R HRR                     S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMS++NV+IFLYQILRGLAYCH+R++LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG P+E TWPGISSN EF +  F     PQ + N  PRL   G+ LLT  L+Y+ KKRISAEDAM+H YF      + +L    +  S+F +  + L  DPG
Sbjct:   33 ENSSKDNDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRR--------------------ISMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYVKLEKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSIHNVKIFLYQILRGLAYCHKRKVLHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPAEETWPGISSNDEFRNYNF-PKYKPQPVINHAPRLDSEGIELLTRFLQYESKKRISAEDAMKHAYFRSLGTKIHSLP---ENISIFSLKDIQLQKDPG 447          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Xenopus
Match: ambn (ameloblastin [Source:Xenbase;Acc:XB-GENE-853786])

HSP 1 Score: 504.982 bits (1299), Expect = 5.310e-173
Identity = 250/371 (67.39%), Postives = 298/371 (80.32%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMS++NV+IFLYQILRGLAYCH+R++LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG P+E TWPGISSN EF +  F     PQ + N  PRL   G+ LLT  L+Y+ KKRISAEDAM+H YF      + +L    +  S+F +  + L  DPG
Sbjct:  114 SMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYVKLEKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSIHNVKIFLYQILRGLAYCHKRKVLHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPAEETWPGISSNDEFRNYNF-PKYKPQPVINHAPRLDSEGIELLTRFLQYESKKRISAEDAMKHAYFRSLGTKIHSLP---ENISIFSLKDIQLQKDPG 479          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Xenopus
Match: ambn (ameloblastin [Source:Xenbase;Acc:XB-GENE-853786])

HSP 1 Score: 504.982 bits (1299), Expect = 1.391e-172
Identity = 250/371 (67.39%), Postives = 298/371 (80.32%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMS++NV+IFLYQILRGLAYCH+R++LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG P+E TWPGISSN EF +  F     PQ + N  PRL   G+ LLT  L+Y+ KKRISAEDAM+H YF      + +L    +  S+F +  + L  DPG
Sbjct:  114 SMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYVKLEKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSIHNVKIFLYQILRGLAYCHKRKVLHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPAEETWPGISSNDEFRNYNF-PKYKPQPVINHAPRLDSEGIELLTRFLQYESKKRISAEDAMKHAYFRSLGTKIHSLP---ENISIFSLKDIQLQKDPG 479          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Xenopus
Match: ambn (ameloblastin [Source:Xenbase;Acc:XB-GENE-853786])

HSP 1 Score: 502.286 bits (1292), Expect = 3.470e-172
Identity = 250/371 (67.39%), Postives = 298/371 (80.32%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMS++NV+IFLYQILRGLAYCH+R++LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG P+E TWPGISSN EF +  F     PQ + N  PRL   G+ LLT  L+Y+ KKRISAEDAM+H YF      + +L    +  S+F +  + L  DPG
Sbjct:   44 SMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYVKLEKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSIHNVKIFLYQILRGLAYCHKRKVLHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPAEETWPGISSNDEFRNYNF-PKYKPQPVINHAPRLDSEGIELLTRFLQYESKKRISAEDAMKHAYFRSLGTKIHSLP---ENISIFSLKDIQLQKDPG 409          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Xenopus
Match: ambn (ameloblastin [Source:Xenbase;Acc:XB-GENE-853786])

HSP 1 Score: 495.352 bits (1274), Expect = 2.727e-171
Identity = 242/337 (71.81%), Postives = 285/337 (84.57%), Query Frame = 3
Query:  810 SDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYF 1808
            +D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMS++NV+IFLYQILRGLAYCH+R++LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG P+E TWPGISSN EF +  F     PQ + N  PRL   G+ LLT  L+Y+ KKRISAEDAM+H YF
Sbjct:   16 NDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYVKLEKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSIHNVKIFLYQILRGLAYCHKRKVLHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPAEETWPGISSNDEFRNYNF-PKYKPQPVINHAPRLDSEGIELLTRFLQYESKKRISAEDAMKHAYF 350          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Mouse
Match: Cdk17 (cyclin-dependent kinase 17 [Source:MGI Symbol;Acc:MGI:97517])

HSP 1 Score: 501.516 bits (1290), Expect = 5.557e-172
Identity = 250/371 (67.39%), Postives = 300/371 (80.86%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATV+KGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMSM+NV++FLYQILRGLAYCHRR++LHRDLKPQNLLIN  RG+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG PS+ TWPG+SSN EF +  F     PQ L N  PRL   G+ L+T  L+Y+ KKR+ AE+AM+H YF RS  P   +  L ++ S+F +  + L  DPG
Sbjct:  104 SMEDLNKRLSLPADIRIPDGYLEKLQISSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINE-RGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKNYNF-PKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVPAEEAMKHVYF-RSLGP--RIHALPESVSIFSLKEIQLQKDPG 469          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Mouse
Match: Cdk17 (cyclin-dependent kinase 17 [Source:MGI Symbol;Acc:MGI:97517])

HSP 1 Score: 502.286 bits (1292), Expect = 1.113e-171
Identity = 250/371 (67.39%), Postives = 300/371 (80.86%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATV+KGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMSM+NV++FLYQILRGLAYCHRR++LHRDLKPQNLLIN  RG+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG PS+ TWPG+SSN EF +  F     PQ L N  PRL   G+ L+T  L+Y+ KKR+ AE+AM+H YF RS  P   +  L ++ S+F +  + L  DPG
Sbjct:  137 SMEDLNKRLSLPADIRIPDGYLEKLQISSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINE-RGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKNYNF-PKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVPAEEAMKHVYF-RSLGP--RIHALPESVSIFSLKEIQLQKDPG 502          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Mouse
Match: Cdk16 (cyclin-dependent kinase 16 [Source:MGI Symbol;Acc:MGI:97516])

HSP 1 Score: 495.352 bits (1274), Expect = 8.052e-170
Identity = 239/366 (65.30%), Postives = 299/366 (81.69%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR---KSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHL 1889
            S  D +KRLSLPA+I LP   L +    S + + P++++ RR SL+EIGFGKLE+Y KLDKLG+GTYATV+KG+S+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT KSLTLVFEYL KDLKQY++DC N+++M+NV++FL+Q+LRGLAYCHR+++LHRDLKPQNLLIN  RG+LKLADFGLARAKSIP KTYSNEVVTLWYRPPD+LLGST+YSTQIDMWGVGCI +EMA GRP+FPGSTV+E+L  IF+ LG P+E TWPGI SN+EF +  +    + ++L +  PRL   G  LLT LL+++G+ RISAEDA +H +F+      E + +L DT S+F +  V L
Sbjct:   75 STEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINE-RGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFRTYNYPKYRA-EALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDARKHPFFLSLG---ERIHKLPDTTSIFALKEVQL 435          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Mouse
Match: Cdk16 (cyclin-dependent kinase 16 [Source:MGI Symbol;Acc:MGI:97516])

HSP 1 Score: 496.123 bits (1276), Expect = 9.864e-170
Identity = 239/366 (65.30%), Postives = 299/366 (81.69%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR---KSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHL 1889
            S  D +KRLSLPA+I LP   L +    S + + P++++ RR SL+EIGFGKLE+Y KLDKLG+GTYATV+KG+S+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT KSLTLVFEYL KDLKQY++DC N+++M+NV++FL+Q+LRGLAYCHR+++LHRDLKPQNLLIN  RG+LKLADFGLARAKSIP KTYSNEVVTLWYRPPD+LLGST+YSTQIDMWGVGCI +EMA GRP+FPGSTV+E+L  IF+ LG P+E TWPGI SN+EF +  +    + ++L +  PRL   G  LLT LL+++G+ RISAEDA +H +F+      E + +L DT S+F +  V L
Sbjct:  110 STEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINE-RGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFRTYNYPKYRA-EALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDARKHPFFLSLG---ERIHKLPDTTSIFALKEVQL 470          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Mouse
Match: Cdk18 (cyclin-dependent kinase 18 [Source:MGI Symbol;Acc:MGI:97518])

HSP 1 Score: 481.871 bits (1239), Expect = 1.046e-164
Identity = 240/371 (64.69%), Postives = 291/371 (78.44%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLP +I LP   L +       L +P+T+  RR SL++IGFGKLE+Y KLDKLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHD+IHT +SLTLVFEYL  DLKQY++ C N+M+M+NV+IF++Q+LRGLAYCH R+ILHRDLKPQNLLIN  RG+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCIL+EMA G+P+FPGSTV EEL LIF+ LG P+E +WPG++S  EF +  F     PQ L +  PRL   G++LL+ LL Y+ K R+SAE A+ H YF       + + +L DT S+F +  + L  DPG
Sbjct:   66 SMEDLNKRLSLPMDIRLPQEFLQKLQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINE-RGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGKPLFPGSTVKEELHLIFRLLGTPTEESWPGVTSISEFRAYNF-PRYLPQPLLSHAPRLDTEGINLLSSLLLYESKSRMSAEAALNHPYFQSLG---DRVHQLHDTASIFSLKEIQLQKDPG 431          
BLAST of Cyclin-dependent kinase 16 vs. UniProt/SwissProt
Match: sp|Q00537|CDK17_HUMAN (Cyclin-dependent kinase 17 OS=Homo sapiens OX=9606 GN=CDK17 PE=1 SV=2)

HSP 1 Score: 504.597 bits (1298), Expect = 8.990e-172
Identity = 251/371 (67.65%), Postives = 302/371 (81.40%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATV+KGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMSM+NV++FLYQILRGLAYCHRR++LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG PS+ TWPGISSN+EF +  F     PQ L N  PRL   G+ L+T  L+Y+ KKR+SAE+AM+H YF RS  P   +  L ++ S+F +  + L  DPG
Sbjct:  137 SMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNF-PKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF-RSLGP--RIHALPESVSIFSLKEIQLQKDPG 502          
BLAST of Cyclin-dependent kinase 16 vs. UniProt/SwissProt
Match: sp|Q8K0D0|CDK17_MOUSE (Cyclin-dependent kinase 17 OS=Mus musculus OX=10090 GN=Cdk17 PE=1 SV=2)

HSP 1 Score: 502.286 bits (1292), Expect = 7.782e-171
Identity = 250/371 (67.39%), Postives = 300/371 (80.86%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATV+KGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMSM+NV++FLYQILRGLAYCHRR++LHRDLKPQNLLIN  RG+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG PS+ TWPG+SSN EF +  F     PQ L N  PRL   G+ L+T  L+Y+ KKR+ AE+AM+H YF RS  P   +  L ++ S+F +  + L  DPG
Sbjct:  137 SMEDLNKRLSLPADIRIPDGYLEKLQISSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINE-RGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKNYNF-PKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVPAEEAMKHVYF-RSLGP--RIHALPESVSIFSLKEIQLQKDPG 502          
BLAST of Cyclin-dependent kinase 16 vs. UniProt/SwissProt
Match: sp|Q00536|CDK16_HUMAN (Cyclin-dependent kinase 16 OS=Homo sapiens OX=9606 GN=CDK16 PE=1 SV=1)

HSP 1 Score: 500.36 bits (1287), Expect = 1.671e-170
Identity = 240/366 (65.57%), Postives = 300/366 (81.97%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR---KSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHL 1889
            S  D +KRLSLPA+I LP   L +    S + + P++++ RR SL+EIGFGKLE+Y KLDKLG+GTYATV+KG+S+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT KSLTLVFEYL KDLKQY++DC NI++M+NV++FL+Q+LRGLAYCHR+++LHRDLKPQNLLIN  RG+LKLADFGLARAKSIP KTYSNEVVTLWYRPPD+LLGST+YSTQIDMWGVGCI +EMA GRP+FPGSTV+E+L  IF+ LG P+E TWPGI SN+EF +  +    + ++L +  PRL   G  LLT LL+++G+ RISAEDAM+H +F+      E + +L DT S+F +  + L
Sbjct:  110 STEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINE-RGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRA-EALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLG---ERIHKLPDTTSIFALKEIQL 470          
BLAST of Cyclin-dependent kinase 16 vs. UniProt/SwissProt
Match: sp|O35831|CDK17_RAT (Cyclin-dependent kinase 17 OS=Rattus norvegicus OX=10116 GN=Cdk17 PE=1 SV=1)

HSP 1 Score: 498.819 bits (1283), Expect = 1.970e-169
Identity = 249/371 (67.12%), Postives = 299/371 (80.59%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLPA+I +P   L +         +PM+++ RR SL+EIGFGK+E+Y KL+KLG+GTYATV+KGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC +IMSM+NV++FLYQILRGLAYCHRR++LHRDLKPQNLLIN  RG+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI FEMA+GRP+FPGSTV++EL LIF+ LG PS+ TWPG+SSN EF +  F     PQ L N  PRL   G+ L+T  L+Y+ KKR  AE+AM+H YF RS  P   +  L ++ S+F +  + L  DPG
Sbjct:  137 SMEDLNKRLSLPADIRIPDGYLEKLQISSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGSIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINE-RGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKNYNF-PKYKPQPLINHAPRLDSEGIELITKFLQYESKKRAPAEEAMKHVYF-RSLGP--RIHALPESVSIFSLKEIQLQKDPG 502          
BLAST of Cyclin-dependent kinase 16 vs. UniProt/SwissProt
Match: sp|O35832|CDK18_RAT (Cyclin-dependent kinase 18 OS=Rattus norvegicus OX=10116 GN=Cdk18 PE=1 SV=1)

HSP 1 Score: 494.967 bits (1273), Expect = 4.791e-169
Identity = 243/371 (65.50%), Postives = 292/371 (78.71%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            S  D +KRLSLP +I LP   L +       L +P+T+  RR SL++IGFGKLE+Y KLDKLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHD+IHT +SLTLVFEYL  DLKQY++ C N+M+M+NV+IF++Q+LRGLAYCHRR+ILHRDLKPQNLLIN  RG+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCIL+EMA G+P+FPGSTV EEL LIF+ LG P+E +WPG++S  EF +  F     PQ L +  PRL   G++LLT LL Y+ K R+SAE A+ H YF       E + +L DT S+F +  + L  DPG
Sbjct:   66 SMEDLNKRLSLPMDIRLPQEFLQKLQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCHRRKILHRDLKPQNLLINE-RGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGKPLFPGSTVKEELHLIFRLLGTPTEESWPGVTSISEFRAYNF-PRYLPQPLLSHAPRLDTEGINLLTSLLLYESKSRMSAEAALSHPYFQSLG---ERVHQLDDTASIFSLKEIQLQKDPG 431          
BLAST of Cyclin-dependent kinase 16 vs. TrEMBL
Match: L7LSQ2 (Putative cyclin-dependent kinase 16 OS=Rhipicephalus pulchellus OX=72859 PE=2 SV=1)

HSP 1 Score: 522.316 bits (1344), Expect = 2.555e-177
Identity = 252/365 (69.04%), Postives = 306/365 (83.84%), Query Frame = 3
Query:  801 SSESDASKRLSLPANINLPPHLLNRKSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLS 1892
            +S+SD SKRLSLPA++ LP   LN+++Q+L+ P+++  RR SL+EIGFGK+E+YTKLDKLG+GTYA VFKG+SRLT++LVALKEIRLEHEEGAPCTAIREVSLL++L H N+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC N +SMN V+ FL+Q+LRGLAYCH RRILHRDLKPQNLLIN  RG+LKLADFGLARAKS+PIKT+SNEVVTLWYRPPDVLLGST+YST IDMWGVGCI +EMA+GRP+FPGSTV++EL LIF+TLG P+EATWPGI S  EF + +F    +P+SL + VPR+   GV+LL   L+++ K RISA+DAM+H YF      V    +L DT S+F +PGV LS
Sbjct:   85 TSQSDISKRLSLPADLRLPESFLNKQAQVLDGPLSRSIRRQSLSEIGFGKMETYTKLDKLGEGTYAMVFKGKSRLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHNNIVTLHDIVHTEKSLTLVFEYLEKDLKQYMDDCGNFLSMNTVKCFLFQLLRGLAYCHGRRILHRDLKPQNLLINE-RGELKLADFGLARAKSVPIKTFSNEVVTLWYRPPDVLLGSTDYSTSIDMWGVGCIFYEMASGRPLFPGSTVEDELHLIFRTLGTPTEATWPGIESRSEFLAYRF-PRYTPESLGSKVPRIGAPGVALLLEFLKFEPKMRISAKDAMRHSYFDSLGPNVH---KLPDTASIFTIPGVQLS 444          
BLAST of Cyclin-dependent kinase 16 vs. TrEMBL
Match: V4A697 (Protein kinase domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_178051 PE=3 SV=1)

HSP 1 Score: 522.702 bits (1345), Expect = 3.450e-177
Identity = 254/367 (69.21%), Postives = 297/367 (80.93%), Query Frame = 3
Query:  813 DASKRLSLPANINLPPHLLNRKSQLLEP---MTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            +  KRLSLPA+I LP + L R+S  L P   +T++ RR SL+EIGFGKLESYTKLDKLG+GTYATVFKG+SRLT++LVALKEIRLEHEEGAPCTAIREVSLLR+L HAN+VTLHDIIHT KSLTLVFEYL KDLKQYM+DC NIMSM NV+IFLYQ+LRGLAYCH+RR+LHRDLKPQNLLIN  RG+LKLADFGLARAKSIP KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCI +EMA GRP+FPGSTV++EL LIFK LG P+E  +PGISSN+E+ S  F+  + P+ L N+ PRL   G+ LL+  L+Y  + R+SA   M H +F         + R+ DT S+F +PG+ L  DPG
Sbjct:   89 EVMKRLSLPADIRLPENFLARQSLSLSPDGQLTRQSRRKSLSEIGFGKLESYTKLDKLGEGTYATVFKGKSRLTDNLVALKEIRLEHEEGAPCTAIREVSLLRDLKHANIVTLHDIIHTEKSLTLVFEYLEKDLKQYMDDCGNIMSMTNVKIFLYQLLRGLAYCHKRRVLHRDLKPQNLLINE-RGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIFYEMACGRPLFPGSTVEDELLLIFKALGTPTEQEFPGISSNEEYVSYNFSRYK-PEPLINIAPRLDHDGLDLLSKFLKYAARNRMSAASGMTHSFFNSFG---STIHRIPDTVSIFTIPGISLHRDPG 450          
BLAST of Cyclin-dependent kinase 16 vs. TrEMBL
Match: L7M149 (Putative cyclin-dependent kinase 16 OS=Rhipicephalus pulchellus OX=72859 PE=2 SV=1)

HSP 1 Score: 522.702 bits (1345), Expect = 4.855e-177
Identity = 252/365 (69.04%), Postives = 306/365 (83.84%), Query Frame = 3
Query:  801 SSESDASKRLSLPANINLPPHLLNRKSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLS 1892
            +S+SD SKRLSLPA++ LP   LN+++Q+L+ P+++  RR SL+EIGFGK+E+YTKLDKLG+GTYA VFKG+SRLT++LVALKEIRLEHEEGAPCTAIREVSLL++L H N+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC N +SMN V+ FL+Q+LRGLAYCH RRILHRDLKPQNLLIN  RG+LKLADFGLARAKS+PIKT+SNEVVTLWYRPPDVLLGST+YST IDMWGVGCI +EMA+GRP+FPGSTV++EL LIF+TLG P+EATWPGI S  EF + +F    +P+SL + VPR+   GV+LL   L+++ K RISA+DAM+H YF      V    +L DT S+F +PGV LS
Sbjct:  113 TSQSDISKRLSLPADLRLPESFLNKQAQVLDGPLSRSIRRQSLSEIGFGKMETYTKLDKLGEGTYAMVFKGKSRLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHNNIVTLHDIVHTEKSLTLVFEYLEKDLKQYMDDCGNFLSMNTVKCFLFQLLRGLAYCHGRRILHRDLKPQNLLINE-RGELKLADFGLARAKSVPIKTFSNEVVTLWYRPPDVLLGSTDYSTSIDMWGVGCIFYEMASGRPLFPGSTVEDELHLIFRTLGTPTEATWPGIESRSEFLAYRF-PRYTPESLGSKVPRIGAPGVALLLEFLKFEPKMRISAKDAMRHSYFDSLGPNVH---KLPDTASIFTIPGVQLS 472          
BLAST of Cyclin-dependent kinase 16 vs. TrEMBL
Match: A0A224YVZ0 (Cyclin dependent kinase 16 OS=Rhipicephalus zambeziensis OX=60191 PE=3 SV=1)

HSP 1 Score: 521.546 bits (1342), Expect = 5.068e-177
Identity = 252/365 (69.04%), Postives = 305/365 (83.56%), Query Frame = 3
Query:  801 SSESDASKRLSLPANINLPPHLLNRKSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLS 1892
            +S+SD SKRLSLPA++ LP   LN++ Q+L+ P+++  RR SL+EIGFGK+E+YTKLDKLG+GTYA VFKG+SRLT++LVALKEIRLEHEEGAPCTAIREVSLL++L H N+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC N +SMN V+ FL+Q+LRGLAYCH RRILHRDLKPQNLLIN  RG+LKLADFGLARAKS+PIKT+SNEVVTLWYRPPDVLLGST+YST IDMWGVGCI +EMA+GRP+FPGSTV++EL LIF+TLG P+EATWPGI S  EF + +F    +P+SL + VPR+   GV+LL   L+++ K RISA+DAM+H YF      V    +L DT S+F +PGV LS
Sbjct:   85 TSQSDISKRLSLPADLRLPESFLNKQQQVLDGPLSRSIRRQSLSEIGFGKMETYTKLDKLGEGTYAMVFKGKSRLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHNNIVTLHDIVHTEKSLTLVFEYLEKDLKQYMDDCGNFLSMNTVKCFLFQLLRGLAYCHGRRILHRDLKPQNLLINE-RGELKLADFGLARAKSVPIKTFSNEVVTLWYRPPDVLLGSTDYSTSIDMWGVGCIFYEMASGRPLFPGSTVEDELHLIFRTLGTPTEATWPGIESRSEFLAYRF-PRYTPESLGSKVPRIGAPGVALLLEFLKFEPKMRISAKDAMRHSYFDSLGPNVH---KLPDTASIFTIPGVQLS 444          
BLAST of Cyclin-dependent kinase 16 vs. TrEMBL
Match: A0A131YDM8 (Cyclin dependent kinase 16 OS=Rhipicephalus appendiculatus OX=34631 PE=3 SV=1)

HSP 1 Score: 521.546 bits (1342), Expect = 5.068e-177
Identity = 252/365 (69.04%), Postives = 305/365 (83.56%), Query Frame = 3
Query:  801 SSESDASKRLSLPANINLPPHLLNRKSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLS 1892
            +S+SD SKRLSLPA++ LP   LN++ Q+L+ P+++  RR SL+EIGFGK+E+YTKLDKLG+GTYA VFKG+SRLT++LVALKEIRLEHEEGAPCTAIREVSLL++L H N+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC N +SMN V+ FL+Q+LRGLAYCH RRILHRDLKPQNLLIN  RG+LKLADFGLARAKS+PIKT+SNEVVTLWYRPPDVLLGST+YST IDMWGVGCI +EMA+GRP+FPGSTV++EL LIF+TLG P+EATWPGI S  EF + +F    +P+SL + VPR+   GV+LL   L+++ K RISA+DAM+H YF      V    +L DT S+F +PGV LS
Sbjct:   85 TSQSDISKRLSLPADLRLPESFLNKQQQVLDGPLSRSIRRQSLSEIGFGKMETYTKLDKLGEGTYAMVFKGKSRLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHNNIVTLHDIVHTEKSLTLVFEYLEKDLKQYMDDCGNFLSMNTVKCFLFQLLRGLAYCHGRRILHRDLKPQNLLINE-RGELKLADFGLARAKSVPIKTFSNEVVTLWYRPPDVLLGSTDYSTSIDMWGVGCIFYEMASGRPLFPGSTVEDELHLIFRTLGTPTEATWPGIESRSEFLAYRF-PRYTPESLGSKVPRIGAPGVALLLEFLKFEPKMRISAKDAMRHSYFDSLGPNVH---KLPDTASIFTIPGVQLS 444          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Cavefish
Match: si:dkey-166c18.1 (cyclin dependent kinase 18 [Source:NCBI gene;Acc:103023181])

HSP 1 Score: 504.212 bits (1297), Expect = 2.419e-173
Identity = 246/376 (65.43%), Postives = 298/376 (79.26%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTV 1919
            S  D SKR+SLP +I LPP  L +      +  +P+++  RR SL++IGFGKLE+Y KL KLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL+NL HAN+VTLHDIIHT + LTLVFEYL  DLKQY+++C N+MS++NV+IF++Q+LRGL+YCH+R+ILHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCIL+EMA GRPMFPGSTV EEL L+F+ +G PSE TWPGI++N+EF S  F   ++ Q+L N VPRL   G+ LL+ LL Y  KKR SAE +++H YF+      E +  L DT SVF +  V L  DPG   +V
Sbjct:   82 SMEDVSKRMSLPMDIRLPPEFLKKLQMESPEPCKPLSRMSRRASLSDIGFGKLETYVKLGKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTDRCLTLVFEYLDSDLKQYLDNCGNLMSIHNVKIFMFQLLRGLSYCHKRKILHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGRPMFPGSTVKEELHLVFRLMGSPSEETWPGITANEEFKSYMFPQYKA-QALINHVPRLDTEGIDLLSALLLYDTKKRSSAEASLRHAYFLSLG---ENIHSLPDTSSVFSLKEVQLQKDPGHRSSV 452          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Cavefish
Match: si:dkey-166c18.1 (cyclin dependent kinase 18 [Source:NCBI gene;Acc:103023181])

HSP 1 Score: 504.212 bits (1297), Expect = 2.419e-173
Identity = 246/376 (65.43%), Postives = 298/376 (79.26%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTV 1919
            S  D SKR+SLP +I LPP  L +      +  +P+++  RR SL++IGFGKLE+Y KL KLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL+NL HAN+VTLHDIIHT + LTLVFEYL  DLKQY+++C N+MS++NV+IF++Q+LRGL+YCH+R+ILHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCIL+EMA GRPMFPGSTV EEL L+F+ +G PSE TWPGI++N+EF S  F   ++ Q+L N VPRL   G+ LL+ LL Y  KKR SAE +++H YF+      E +  L DT SVF +  V L  DPG   +V
Sbjct:   82 SMEDVSKRMSLPMDIRLPPEFLKKLQMESPEPCKPLSRMSRRASLSDIGFGKLETYVKLGKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTDRCLTLVFEYLDSDLKQYLDNCGNLMSIHNVKIFMFQLLRGLSYCHKRKILHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGRPMFPGSTVKEELHLVFRLMGSPSEETWPGITANEEFKSYMFPQYKA-QALINHVPRLDTEGIDLLSALLLYDTKKRSSAEASLRHAYFLSLG---ENIHSLPDTSSVFSLKEVQLQKDPGHRSSV 452          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Cavefish
Match: cdk17 (cyclin dependent kinase 17 [Source:NCBI gene;Acc:103026120])

HSP 1 Score: 503.056 bits (1294), Expect = 7.400e-173
Identity = 269/441 (61.00%), Postives = 318/441 (72.11%), Query Frame = 3
Query:  621 EEEAKDRFVVIEKGKCYVDGELVQG--------LSPSQLAQVRRRHRRPXXXXXXXXXXXXXXERGIDSSESDASKRLSLPANINLPPHLLNRKSQLL-----EPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            E  +KD  +V E  K   DGE  Q          SP+ +    R HRR                     S  D +KRLSLPA+I +P   L  K QL      +P++++ RR SL+EIGFGKLE+Y KLDKLG+GTYATVFKGRS+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMSM+NV+IFL+QILRGLAYCHRR++LHRDLKPQNLLIN  RG+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGS+ YSTQIDMWGVGCI +EMAAGRP+FPGSTV++EL LIF+ LG P+E  WPGISS +EF S  F     PQ   N  PRL   G+ LL   L+Y+ KKRISA+D+M+H YF    + V  L    ++ S+F +  V L  DPG
Sbjct:   33 ENSSKDSDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRTRTHRR--------------------ISMEDLNKRLSLPADIRIPDGYLE-KLQLSSPPFDQPLSRRSRRASLSEIGFGKLETYIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKIFLFQILRGLAYCHRRKVLHRDLKPQNLLINE-RGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFYEMAAGRPLFPGSTVEDELHLIFRLLGTPTEENWPGISSIEEFKSYNF-PKYKPQPFINHAPRLDTEGIELLLSFLKYESKKRISADDSMKHSYFKSLGMRVHTLP---ESISIFTLKEVQLQRDPG 447          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Cavefish
Match: cdk16 (cyclin-dependent kinase 16 [Source:ZFIN;Acc:ZDB-GENE-030131-2939])

HSP 1 Score: 500.36 bits (1287), Expect = 8.913e-172
Identity = 250/377 (66.31%), Postives = 301/377 (79.84%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR---KSQLLE-PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVA 1922
            S  D +KRLSLPA+I LP   L +    S L + P++++ RR SL+EIGFGKLE+Y KLDKLG+GTYATV+KGRS+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT KSLTLVFEYL KDLKQY++DC N + M+NV++FL+Q+LRGL YCHRR++LHRDLKPQNLLIN  RG+LKLADFGLARAKSIP KTYSNEVVTLWYRPPD+LLGST+YSTQIDMWGVGCI +EMA GRP+FPGSTV+EEL  IFK LG P+E TWPGI+SN+EF S  +    +   L N  PRL   GV LL+ LL+++GKKRISAE+AM+H YF       E +  L DT S+F +  + L  +  S RT +
Sbjct:   94 STEDINKRLSLPADIRLPDGYLEKFSLNSPLFDKPLSRRLRRVSLSEIGFGKLETYVKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTQKSLTLVFEYLDKDLKQYLDDCGNCIHMHNVKLFLFQLLRGLNYCHRRKVLHRDLKPQNLLIND-RGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEELHFIFKLLGTPTEETWPGITSNEEFISYNYPRYRA-DCLHNHTPRLDNDGVDLLSKLLQFEGKKRISAEEAMRHSYF---HCLGERVLTLPDTTSIFALQNIQLEKET-SMRTAS 464          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Cavefish
Match: ENSAMXT00000030743.1 (cyclin-dependent kinase 17-like [Source:NCBI gene;Acc:103047068])

HSP 1 Score: 500.36 bits (1287), Expect = 1.730e-171
Identity = 243/379 (64.12%), Postives = 302/379 (79.68%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNRKSQ----LLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHT 1928
            S  D +KRLSLP +I LP   L + +       +P++++ RR SL+EIGFGKLE+Y KLDKLG+GTYATVFKGRS+LT+SLVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT K LTLVFEYL KDLKQYM+DC NIMS++NV+IFL+Q+LRGLAYCHRR++LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCI +EM  GRP+FPGSTV++EL LIF+ LG P+E +WPG+S+++EF +  F    + + L N  PR+   G  L+  LL+++ K+R+SAE+A++H YF      V+ L+   DT S+F V  + L  DPG  R+VA++
Sbjct:   86 SNEDINKRLSLPVDIRLPEGYLEKFAMNSPPFDKPLSRRLRRASLSEIGFGKLETYIKLDKLGEGTYATVFKGRSKLTDSLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTDKCLTLVFEYLEKDLKQYMDDCGNIMSVHNVKIFLFQLLRGLAYCHRRKVLHRDLKPQNLLIND-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIFYEMITGRPLFPGSTVEDELHLIFRILGTPTEESWPGVSTSEEFRTYNFPRYRT-EPLVNHAPRIDSDGHDLINQLLQFEAKRRVSAEEALRHPYFRSLGEQVQGLA---DTASIFSVKEIQLQKDPGK-RSVAYS 458          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008013.1 (pep scaffold:Pmarinus_7.0:GL478839:10839:40406:1 gene:ENSPMAG00000007231.1 transcript:ENSPMAT00000008013.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 495.738 bits (1275), Expect = 2.139e-170
Identity = 239/339 (70.50%), Postives = 280/339 (82.60%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNR----KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYF 1808
            S+ D +KRLSLPA+I LP   L +          P++++ RR SL+EIGFGKLE+YTKLDKLG+GTYATV+KGRS+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDI+HT KSLTLVFEYL KDLKQYM+DC NIMSM+NV+IFL Q+LRGLAYCH+RR+LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YSTQIDMWGVGCI FEMAAGRP+FPGSTV++EL LIF+ LG P E  WPGISSN+E+ S  F    S + +    PRL   G+ LL+  L Y+ K RISAEDA++  YF
Sbjct:  143 SQEDLNKRLSLPADIRLPEGYLEKFQLNGRSFDAPLSRRLRRASLSEIGFGKLETYTKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLEKDLKQYMDDCGNIMSMHNVKIFLLQLLRGLAYCHKRRVLHRDLKPQNLLIND-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTQIDMWGVGCIFFEMAAGRPLFPGSTVEDELHLIFRMLGSPREDMWPGISSNEEYKSYNFPKYRS-EPMITHAPRLDVDGLDLLSKFLLYEAKARISAEDALKRPYF 479          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741])

HSP 1 Score: 288.886 bits (738), Expect = 1.013e-92
Identity = 143/289 (49.48%), Postives = 202/289 (69.90%), Query Frame = 3
Query:  948 LESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHE-EGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCA-NIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYF 1808
            ++++ K++K+G+GTY  V+K R++LT   VALK+IRL+ E EG P TAIRE+SLLR L+H N+V L  IIH+ K L LVFE L +DLK++M++   + + +  V+ +LYQ+L+G+A+CH  RILHRDLKPQNLLIN   G +KLADFGLARA  +P +TY++EVVTLWYR P++LLG  +YST +D+W +GCI  EM   R +FPG +  ++L  IF+TLG P E  WPG+S   ++ S       + Q L  +VP L F G  LL  +L+Y   +R++A  A+ H +F
Sbjct:    1 MDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLIN-AEGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYKST--FPRWANQELTKVVPTLNFEGRDLLALMLQYDPNQRVTANMALSHCFF 286          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Sea Lamprey
Match: CDK17 (cyclin dependent kinase 17 [Source:HGNC Symbol;Acc:HGNC:8750])

HSP 1 Score: 283.493 bits (724), Expect = 1.583e-91
Identity = 139/225 (61.78%), Postives = 171/225 (76.00%), Query Frame = 3
Query: 1251 VQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAH 1925
            VQ+FLYQ+LRGLAYCH+RR+LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCI FEMAAGRP+FPGSTV++EL LIF+ LG PSE TWP I +++E+ + +F   ++ + L N  PRL   G+ LL+ LL+Y+ ++R+SAE+ M+H YF       E L +L D  S+F +  V L  D G   T  H
Sbjct:    9 VQLFLYQLLRGLAYCHKRRVLHRDLKPQNLLIND-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIFFEMAAGRPLFPGSTVEDELLLIFRMLGTPSEDTWPAILAHEEYKAYKFPKYKA-EPLINHAPRLDADGLDLLSKLLQYEARRRVSAEEGMRHPYFKSLG---ERLHKLPDVVSIFALKEVQLQRDLGHRTTPYH 228          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741])

HSP 1 Score: 280.026 bits (715), Expect = 2.404e-89
Identity = 137/289 (47.40%), Postives = 200/289 (69.20%), Query Frame = 3
Query:  948 LESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHE-EGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANI-MSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYF 1808
            ++ + K++K+G+GTY  V+K R ++T   VALK+IRL+ E EG P TAIRE++LLR L+H N+V L D+IH+   L LVFE+L +DLK+YM++   + +S+  V+ +++Q+L+G+A+CH +R LHRDLKPQNLLIN   G +KLADFGLARA  +P++TY++EVVTLWYR P++LLG   YST +D+W +GCI  EM   R +FPG +  ++L  IF+TLG P E  W GI+   ++  +        Q L  +VP L   G  LL  +L+Y   +R+SA+ A+ H +F
Sbjct:    1 MDLFQKVEKIGEGTYGVVYKARHKMTGDTVALKKIRLDTETEGVPSTAIREIALLRELNHPNIVRLLDVIHSETKLYLVFEFLDQDLKKYMDNAPPLGISLPLVKSYMHQLLQGIAFCHAQRTLHRDLKPQNLLIN-ADGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKYYSTAVDVWSLGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDETVWQGITQLPDY--KPSFPRWCAQDLTKVVPLLDAAGHDLLMQMLQYDPTRRVSAKAALNHHFF 286          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005451.1 (pep scaffold:Pmarinus_7.0:GL478132:187045:200874:-1 gene:ENSPMAG00000004949.1 transcript:ENSPMAT00000005451.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 271.552 bits (693), Expect = 6.537e-86
Identity = 154/304 (50.66%), Postives = 201/304 (66.12%), Query Frame = 3
Query:  939 FGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPG-STVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQF--NASESPQSLFNLVPRLQFTGV-----SLLTGLLEYQGKKRISAEDAMQHDYFVRSSLP 1826
            FG    Y +L K+GQG+YATVFKG SR+T   VALK + +  EEGAP   IREVSLL+ L HAN+V LHDI++T  +LTLVFEYL  DL QYME     ++ +NV++FL Q+LRGLAY H R ILHRD+KP NLL+  V G+LKLADFG+ARA+S+P ++YS+EV TLWYRPPDVLLGST YS+ +DMW VGCI  EM  G  +FPG   V ++L+ +++ LG P+E  WP ++S   +   +F    S  P+    L    +  G       L   LL+    +R+ A  A++H YF  S LP
Sbjct:    6 FGGEALYVRLQKIGQGSYATVFKGISRVTWQFVALKVVYIHEEEGAPFNTIREVSLLKTLKHANIVLLHDIVYTQHALTLVFEYLETDLHQYMERHPGGLNAHNVKLFLLQLLRGLAYTHSRGILHRDVKPHNLLLG-VSGELKLADFGMARAQSVPSRSYSSEVATLWYRPPDVLLGSTRYSSGLDMWAVGCIFVEMLQGMVIFPGVPGVWDQLERVWQVLGTPNEEEWPEVTSLPLYKPGEFCLETSIVPKKPRQLGRVWRMLGCDPHAEDLARSLLQCCPSRRLPAHAALRHSYF--SDLP 306          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952])

HSP 1 Score: 293.508 bits (750), Expect = 1.133e-94
Identity = 145/296 (48.99%), Postives = 199/296 (67.23%), Query Frame = 3
Query:  957 YTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYME-----DCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPR------LQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFV 1811
            + +L+KLG GTYATV+KG ++ T   VALKE++L+ EEG P TAIRE+SL++ L H N+V L+D+IHT   LTLVFE++  DLK+YM+     +    + +N V+ F +Q+L+GLA+CH  +ILHRDLKPQNLLIN  RG LKL DFGLARA  IP+ T+S+EVVTLWYR PDVL+GS  YST ID+W  GCIL EM  G+P+FPG+  +E+L+LIF  +G P+E+ WP ++   ++     N  + P      V +      L    +  L GLL+     R+SA+ A+ H +F 
Sbjct:    7 FKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINK-RGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNP---NIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFA 298          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Yeast
Match: CDC28 (Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364])

HSP 1 Score: 263.077 bits (671), Expect = 5.166e-83
Identity = 142/299 (47.49%), Postives = 189/299 (63.21%), Query Frame = 3
Query:  942 GKLESYTKLDKLGQGTYATVFKG---RSRLTESLVALKEIRLEHE-EGAPCTAIREVSLLRNLHHANVVTLHDIIHT-VKSLTLVFEYLHKDLKQYMEDCA--NIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRS 1817
            G+L +Y +L+K+G+GTY  V+K    R    + +VALK+IRLE E EG P TAIRE+SLL+ L   N+V L+DI+H+    L LVFE+L  DLK+YME       +  + V+ F+ Q+ +G+AYCH  RILHRDLKPQNLLIN   G+LKL DFGLARA  +P++ Y++E+VTLWYR P+VLLG   YST +D W +GCI  EM   +P+F G +  +++  IF+ LG P+EA WP I    +F           + L  +VP L   G+ LL  LL Y    RISA  A  H YF  S
Sbjct:    3 GELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINK-DGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPS--FPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQES 298          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Yeast
Match: CTK1 (Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622])

HSP 1 Score: 213.001 bits (541), Expect = 1.377e-61
Identity = 120/300 (40.00%), Postives = 178/300 (59.33%), Query Frame = 3
Query:  957 YTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHE-EGAPCTAIREVSLLRNLHHANVVTLHDI-IHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEF--------TSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLP 1826
            Y ++ ++G+GTY  V+K ++  TE LVALK++RL+ E EG P T+IRE+ LL++  H NV T+ +I + + K++ ++FEY   DL   + +    +S +  +    Q+L G+ Y H  +ILHRD+K  N+LI+  +G+LK+ DFGLAR K      Y+N V+TLWYRPP++LLG+TNY T++DMWG GC+L E+     +F GS   E+++ IFK +G P+  +WP +     F        T    N SE  +S+      LQ     L   LL Y   KR SA +A+Q DYF     P
Sbjct:  183 YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDN-QGNLKITDFGLAR-KMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEKFKSVLPSSKCLQ-----LAINLLCYDQTKRFSATEALQSDYFKEEPKP 475          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Yeast
Match: KIN28 (Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266])

HSP 1 Score: 204.527 bits (519), Expect = 6.946e-61
Identity = 106/285 (37.19%), Postives = 164/285 (57.54%), Query Frame = 3
Query:  957 YTKLDKLGQGTYATVFKGRSRLTESLVALKEIRL-EHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYF 1808
            YTK  K+G+GTYA V+ G    T   +A+KEI+  E ++G   +AIREV  L+ + H NV+ L DI     +L LV E+L  DL+  ++D + + +  +++ ++   LRG+ +CHR  ILHRDLKP NLL +P  G +K+ADFGLARA   P +  ++ VVT WYR P++L G+ +Y++ ID+W VG I  E+    P  PG    +++++ F+ LG P++  WP +SS   +   Q     S   L           +  + G+L    +KR +A   ++ DYF
Sbjct:    7 YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSP-DGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYF 290          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Yeast
Match: KSS1 (Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272])

HSP 1 Score: 165.622 bits (418), Expect = 7.198e-46
Identity = 107/314 (34.08%), Postives = 168/314 (53.50%), Query Frame = 3
Query:  933 IGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLH-HANVVTLHDIIHTV-----KSLTLVFEYLHKDLKQYMED---CANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLAR-------AKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSN--KEFTS----RQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYF 1808
            I F     Y  +D +G+G Y TV     + +   VA+K+I+   ++      IRE+ LLR  H H N++++ D +  V      ++ LV E +  DL++ + +     + +S ++VQ F YQILR L   H  +++HRD+KP NLL+N    DLK+ DFGLAR       ++   +   +  V T WYR P+++L    Y+T +D+W  GCIL EM +G+P+FPG     +L LI + LG PS   +  I S   KE+ +    R     E+  S  +L P +    + LL  +L++   KRISA +A++H Y 
Sbjct:    5 ITFDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNS-NCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDM----IDLLDKMLQFNPDKRISAAEALRHPYL 313          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Nematostella
Match: EDO48117 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK70])

HSP 1 Score: 471.085 bits (1211), Expect = 4.753e-163
Identity = 228/327 (69.72%), Postives = 271/327 (82.87%), Query Frame = 3
Query:  927 AEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESP-QSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            +E+G+GK+E+YTKLDKLG+GTYATVFKG+S+LT+++VALKEIRLEHEEGAPCTAIREVSLL+ L HAN+VTLHD +HT KSLTLVFEYL KDLKQYM+DC  IMSMNNV+IFL+Q+LRGL YCH+R++LHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YSTQIDMWGVGCI FEMA GRP+FPGSTV++EL LIFK LG PSE  WPGIS+N+ F + +F   + P ++L    PRL  +G+ LL   LEY  K R+SA DAM+HDYF   SL    L+ L D DS+F +  + L+ DPG
Sbjct:    1 SELGYGKMETYTKLDKLGEGTYATVFKGKSKLTDNIVALKEIRLEHEEGAPCTAIREVSLLKGLKHANIVTLHDTVHTQKSLTLVFEYLEKDLKQYMDDCGGIMSMNNVRIFLFQLLRGLDYCHKRKVLHRDLKPQNLLIND-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTAYSTQIDMWGVGCIFFEMATGRPLFPGSTVEDELLLIFKVLGTPSEEVWPGISANEAFIAGKF--PDYPRENLIIHAPRLDNSGLELLEKFLEYTVKDRVSAHDAMRHDYFY--SLGTRCLN-LGDLDSLFSLEEIRLTKDPG 321          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Nematostella
Match: EDO43819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXQ4])

HSP 1 Score: 329.331 bits (843), Expect = 4.338e-106
Identity = 173/351 (49.29%), Postives = 235/351 (66.95%), Query Frame = 3
Query:  864 LLNRKSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPG--STVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRL-QFTGVS-LLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPG 1904
            +L    +L +   K+D         +G+LESY KL+ LG+G+YATVFKG     + +VALK+IRL+ EEGAP TAIRE SLL+ L H N+V LHDIIHT  +L  VFE+L  DL  Y+E  +  +  +N Q+F +Q+LRGLAY H R+ILHRD+KPQNLLI+  RG+LKLADFGLARAKS+P +TYS+EVVTLWYRPPDVLLGS NY+T +D+WG GCI  EM  G  +FPG    +D +L  I++ LG P++ TWPG+S   E+    F  +  P+ +   +PRL    G   L+  +++   K RISA +AM+  YF  S+LP E  + ++D D+++ V GV +  +P 
Sbjct:   93 ILGDSRRLSDEFVKEDLPIPPLSPSYGRLESYQKLEPLGEGSYATVFKGLCTANKKIVALKQIRLQEEEGAPFTAIREASLLKQLKHGNIVKLHDIIHTKDTLMFVFEFLDTDLNCYLEKYSRGICPHNTQLFCFQLLRGLAYIHDRKILHRDIKPQNLLISE-RGELKLADFGLARAKSVPSQTYSHEVVTLWYRPPDVLLGSKNYTTSLDIWGAGCIFVEMLTGIALFPGLNGHID-QLNKIWQVLGTPTDETWPGVSKLPEYDPDIF-INFRPRRIGQCIPRLVPIEGAEQLVIRMIQLDPKNRISAREAMRSTYF--SNLPKEIYT-IRDEDTIYSVSGVEIQKEPA 437          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Nematostella
Match: EDO49420 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGF7])

HSP 1 Score: 318.931 bits (816), Expect = 3.875e-104
Identity = 153/290 (52.76%), Postives = 208/290 (71.72%), Query Frame = 3
Query:  948 LESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHE-EGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMA-AGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFV 1811
            ++ Y KL+K+G+GTY TVFKG+++ T  ++ALK +RL+ + EG P +A+RE+ LL+ L H N+V L+D++H+ K LTLVFE+  +DLK+Y + C   +  + V+ F++Q+LRGLA+CH   +LHRDLKPQNLLIN   G+LKLADFGLARA  IP++ +S EVVTLWYRPPDVL+G+  YST IDMW  GCI  EMA  GRP+FPG+ VD++L+ IFK LG P+E +WP +S   ++  ++F       SL  +VP+L  TG  LL  LL      RISAEDAM+H YF 
Sbjct:    1 MQKYDKLEKIGEGTYGTVFKGKNKETREILALKRVRLDDDDEGVPSSALREICLLKELKHNNIVRLYDVLHSEKKLTLVFEFCDQDLKKYFDSCQGEVDASVVKSFMFQLLRGLAFCHSHNVLHRDLKPQNLLINK-DGELKLADFGLARAFGIPVRCFSAEVVTLWYRPPDVLMGAKLYSTSIDMWSAGCIFAEMANGGRPLFPGNDVDDQLRRIFKILGTPTEESWPNVSKLPDY--KEFPPQGPSVSLGMVVPKLSSTGRDLLQKLLVSNPAHRISAEDAMKHAYFA 287          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Nematostella
Match: EDO41403 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4F0])

HSP 1 Score: 294.278 bits (752), Expect = 1.212e-94
Identity = 144/291 (49.48%), Postives = 209/291 (71.82%), Query Frame = 3
Query:  948 LESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHE-EGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDC--ANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESP-QSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYF 1808
            +E++ K++K+G+GTY  V+K R + T  +VALK+IRL+ E EG P TAIRE+SLL+ L+H NVV+L D++H  KSL LVFE+L +DLK+YM DC   + +S + ++ ++YQ+L G+AYCH  R+LHRDLKPQNLLI+   G +KLADFGLARA  +P+++Y++EVVTLWYR P++LLGS  Y+T +D+W +GCI  EM   R +FPG +  ++L  IF+TLG P +  WPG+S   E    + +  + P QS+ +++P L  T + LL  +L YQ   RISA+ A+ H++F
Sbjct:    1 MENFEKVEKIGEGTYGVVYKARDKTTGRMVALKKIRLDTESEGVPSTAIREISLLKELNHPNVVSLLDVVHNQKSLYLVFEFLSQDLKKYM-DCLPPSGISTSLIKSYVYQLLSGVAYCHSHRVLHRDLKPQNLLIDK-NGAIKLADFGLARAFGVPVRSYTHEVVTLWYRAPEILLGSRYYATPVDVWSIGCIFAEMKTRRALFPGDSEIDQLFRIFRTLGTPDDKVWPGVS---ELPDYKTSFPKWPVQSIRHVLPTLDNTAIDLLQKMLTYQPNARISAKAALSHEFF 286          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Nematostella
Match: EDO43671 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXS1])

HSP 1 Score: 265.388 bits (677), Expect = 2.098e-83
Identity = 138/309 (44.66%), Postives = 198/309 (64.08%), Query Frame = 3
Query:  948 LESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHE-EGAPCTAIREVSLLRNL-HHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRS-SLPVEALSRLKDTDSV 1865
            ++ ++K++K+G+GTY  V+K ++  T    ALK+IRLE E EG P TA+RE+SLL+ L HH NVV L  I+H    L LVFEYL  DLK++++    ++    V+ +LYQI   + +CH RRILHRDLKPQNLLI+  +G +KLADFGL RA  IP++ Y++EVVTLWYR P+VLLG   YS  ID+W +G I  EM   RP+F G +  ++L  IF+ LG P+E TW G++S  ++  +      +   L   VP+L   G+ LL  +L Y    RISA+ +++H YF+      + +L +  + DSV
Sbjct:    1 MDDFSKIEKIGEGTYGVVYKAKNLKTGGFAALKKIRLEVEDEGIPSTAVREISLLKELRHHPNVVELQHILHQEPKLYLVFEYLTCDLKKHLDTTRGMLDKTLVKSYLYQITNAIYFCHARRILHRDLKPQNLLIDS-KGLIKLADFGLGRAFGIPVRAYTHEVVTLWYRAPEVLLGGQRYSCPIDVWSIGTIFAEMVTKRPLFHGDSEIDQLFRIFRILGTPTEETWKGVTSLPDY--KPTFPKWAGDGLKKAVPQLDSDGLDLLKKMLIYDPALRISAKTSLKHPYFLNDPKFDINSLPKTPEVDSV 306          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Medaka
Match: ENSORLT00000011316.2 (cyclin-dependent kinase 17 [Source:NCBI gene;Acc:101161555])

HSP 1 Score: 509.99 bits (1312), Expect = 1.508e-175
Identity = 255/399 (63.91%), Postives = 309/399 (77.44%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNRKSQ----LLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLXXXXXXXNQKKRPQSVIY 1988
            S  D +KRLSLPA+I LP   L + +       +PM+++ RR SL+EIGFGKLE+Y KLDKLG+GTYATVFKGRS+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT K LTLVFEYL KDLKQYM+DC NIMS+NNV+IFLYQ+LRGLAYCHRR++LHRDLKPQNLLI+  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCI +EM  GRP+FPGSTV++EL LIF+ LG P+E TWPG+ +++EF +  F    + + L N  PR+   G  LL+ LL++  KKR+SAEDA++H YF   SL  E +  L DT S+F V G+ L  DPG  R+  H         +  K R QSV++
Sbjct:   86 SNEDINKRLSLPADIRLPEGYLEKFAMNSPPFDKPMSRRLRRASLSEIGFGKLETYIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTDKCLTLVFEYLEKDLKQYMDDCGNIMSVNNVKIFLYQLLRGLAYCHRRKVLHRDLKPQNLLISE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIFYEMITGRPLFPGSTVEDELHLIFRVLGTPTEKTWPGMPTSEEFKTYNFPLYRA-EPLVNHAPRIDSDGHDLLSKLLQFDAKKRVSAEDALKHSYF--RSLG-EQVQTLPDTASIFSVKGIQLQKDPGK-RSSVHPE------STQGKSRRQSVLF 472          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Medaka
Match: ENSORLT00000011319.2 (cyclin-dependent kinase 17 [Source:NCBI gene;Acc:101161555])

HSP 1 Score: 508.834 bits (1309), Expect = 6.986e-175
Identity = 255/399 (63.91%), Postives = 309/399 (77.44%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNRKSQ----LLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLXXXXXXXNQKKRPQSVIY 1988
            S  D +KRLSLPA+I LP   L + +       +PM+++ RR SL+EIGFGKLE+Y KLDKLG+GTYATVFKGRS+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT K LTLVFEYL KDLKQYM+DC NIMS+NNV+IFLYQ+LRGLAYCHRR++LHRDLKPQNLLI+  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCI +EM  GRP+FPGSTV++EL LIF+ LG P+E TWPG+ +++EF +  F    + + L N  PR+   G  LL+ LL++  KKR+SAEDA++H YF   SL  E +  L DT S+F V G+ L  DPG  R+  H         +  K R QSV++
Sbjct:  104 SNEDINKRLSLPADIRLPEGYLEKFAMNSPPFDKPMSRRLRRASLSEIGFGKLETYIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTDKCLTLVFEYLEKDLKQYMDDCGNIMSVNNVKIFLYQLLRGLAYCHRRKVLHRDLKPQNLLISE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIFYEMITGRPLFPGSTVEDELHLIFRVLGTPTEKTWPGMPTSEEFKTYNFPLYRA-EPLVNHAPRIDSDGHDLLSKLLQFDAKKRVSAEDALKHSYF--RSLG-EQVQTLPDTASIFSVKGIQLQKDPGK-RSSVHPE------STQGKSRRQSVLF 490          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Medaka
Match: ENSORLT00000011315.2 (cyclin-dependent kinase 17 [Source:NCBI gene;Acc:101161555])

HSP 1 Score: 508.449 bits (1308), Expect = 1.860e-174
Identity = 249/376 (66.22%), Postives = 300/376 (79.79%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNRKSQ----LLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTV 1919
            S  D +KRLSLPA+I LP   L + +       +PM+++ RR SL+EIGFGKLE+Y KLDKLG+GTYATVFKGRS+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT K LTLVFEYL KDLKQYM+DC NIMS+NNV+IFLYQ+LRGLAYCHRR++LHRDLKPQNLLI+  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCI +EM  GRP+FPGSTV++EL LIF+ LG P+E TWPG+ +++EF +  F    + + L N  PR+   G  LL+ LL++  KKR+SAEDA++H YF   SL  E +  L DT S+F V G+ L  DPG   +V
Sbjct:   96 SNEDINKRLSLPADIRLPEGYLEKFAMNSPPFDKPMSRRLRRASLSEIGFGKLETYIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTDKCLTLVFEYLEKDLKQYMDDCGNIMSVNNVKIFLYQLLRGLAYCHRRKVLHRDLKPQNLLISE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIFYEMITGRPLFPGSTVEDELHLIFRVLGTPTEKTWPGMPTSEEFKTYNFPLYRA-EPLVNHAPRIDSDGHDLLSKLLQFDAKKRVSAEDALKHSYF--RSLG-EQVQTLPDTASIFSVKGIQLQKDPGKRSSV 466          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Medaka
Match: ENSORLT00000036083.1 (cyclin-dependent kinase 17 [Source:NCBI gene;Acc:101161555])

HSP 1 Score: 508.449 bits (1308), Expect = 1.860e-174
Identity = 249/376 (66.22%), Postives = 300/376 (79.79%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNRKSQ----LLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTV 1919
            S  D +KRLSLPA+I LP   L + +       +PM+++ RR SL+EIGFGKLE+Y KLDKLG+GTYATVFKGRS+LT++LVALKEIRLEHEEGAPCTAIREVSLL++L HAN+VTLHDIIHT K LTLVFEYL KDLKQYM+DC NIMS+NNV+IFLYQ+LRGLAYCHRR++LHRDLKPQNLLI+  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YST IDMWGVGCI +EM  GRP+FPGSTV++EL LIF+ LG P+E TWPG+ +++EF +  F    + + L N  PR+   G  LL+ LL++  KKR+SAEDA++H YF   SL  E +  L DT S+F V G+ L  DPG   +V
Sbjct:   96 SNEDINKRLSLPADIRLPEGYLEKFAMNSPPFDKPMSRRLRRASLSEIGFGKLETYIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTDKCLTLVFEYLEKDLKQYMDDCGNIMSVNNVKIFLYQLLRGLAYCHRRKVLHRDLKPQNLLISE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIFYEMITGRPLFPGSTVEDELHLIFRVLGTPTEKTWPGMPTSEEFKTYNFPLYRA-EPLVNHAPRIDSDGHDLLSKLLQFDAKKRVSAEDALKHSYF--RSLG-EQVQTLPDTASIFSVKGIQLQKDPGKRSSV 466          
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Medaka
Match: si:dkey-166c18.1 (cyclin dependent kinase 18 [Source:NCBI gene;Acc:101174585])

HSP 1 Score: 502.671 bits (1293), Expect = 1.575e-172
Identity = 247/378 (65.34%), Postives = 295/378 (78.04%), Query Frame = 3
Query:  804 SESDASKRLSLPANINLPPHLLNRKSQLLE------PMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTV 1919
            S  D SKR+SLP +I LPP  L +  Q  E      P+T+  RR SL++IGFGKLE+Y KL KLG+GTYATVFKGRS+LTE+LVALKEIRLEHEEGAPCTAIREVSLL+NL HAN+VTLHDIIHT + LTLVFEYL +DLK Y+++C ++MSM+NV+IF++Q+LRGLAYCH+R+ILHRDLKPQNLLIN  +G+LKLADFGLARAKS+P KTYSNEVVTLWYRPPDVLLGST YS  IDMWGVGCIL+EMA GRPMFPG+TV EEL LIF+ +G P+E TWPGI SN+EF S  F     PQ L N VPRL   G+ LL+ LL Y  + RIS+EDA++H YF+      + +  L DT SVF +  + L  DPG   +V
Sbjct:   98 SMEDVSKRMSLPMDIRLPPEFLKKLQQESENSAPCKPLTRMSRRASLSDIGFGKLETYVKLGKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTDRCLTLVFEYLDRDLKHYLDNCGSLMSMHNVKIFMFQLLRGLAYCHKRKILHRDLKPQNLLIND-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSMHIDMWGVGCILYEMATGRPMFPGATVKEELHLIFRLMGTPTEETWPGIGSNEEFRSYLF-PQYKPQGLINHVPRLDTEGIDLLSALLLYDIRSRISSEDALRHPYFLSLG---DNIHNLADTASVFSLRELQLQKDPGHRSSV 470          
BLAST of Cyclin-dependent kinase 16 vs. Planmine SMEST
Match: SMESG000023149.1 (SMESG000023149.1)

HSP 1 Score: 1152.5 bits (2980), Expect = 0.000e+0
Identity = 638/638 (100.00%), Postives = 638/638 (100.00%), Query Frame = 3
Query:   75 MKDLKKRFSFSGKKNLNDKIESQIENLXXXXXXXXXXXXXXXXXXXXXXXYDSNPSQRNNSHMYGECNGSFNSNINSTSCAIYNQYHNPPVTSNNNHFHIAXXXXXXXXXXXXXXXXXXXNQCNGMSSYNENGCHXXXXXXXXXLLNHCRSNTDLVSQLTGPPNSSYNRSQSCSVSMAIGDHEEEAKDRFVVIEKGKCYVDGELVQGLSPSQLAQVRRRHRRPXXXXXXXXXXXXXXERGIDSSESDASKRLSLPANINLPPHLLNRKSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLXXXXXXXNQKKRPQSVIY 1988
            MKDLKKRFSFSGKKNLNDKIESQIENLSIDSKNSNESNSNNYNNFQNGVSYDSNPSQRNNSHMYGECNGSFNSNINSTSCAIYNQYHNPPVTSNNNHFHIAVSHVPSSFGSSTTSSEIISNQCNGMSSYNENGCHSVSSSSASSLLNHCRSNTDLVSQLTGPPNSSYNRSQSCSVSMAIGDHEEEAKDRFVVIEKGKCYVDGELVQGLSPSQLAQVRRRHRRPGNSGVMSVSGGNGVERGIDSSESDASKRLSLPANINLPPHLLNRKSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLSSSSSHSNQKKRPQSVIY
Sbjct:    1 MKDLKKRFSFSGKKNLNDKIESQIENLSIDSKNSNESNSNNYNNFQNGVSYDSNPSQRNNSHMYGECNGSFNSNINSTSCAIYNQYHNPPVTSNNNHFHIAVSHVPSSFGSSTTSSEIISNQCNGMSSYNENGCHSVSSSSASSLLNHCRSNTDLVSQLTGPPNSSYNRSQSCSVSMAIGDHEEEAKDRFVVIEKGKCYVDGELVQGLSPSQLAQVRRRHRRPGNSGVMSVSGGNGVERGIDSSESDASKRLSLPANINLPPHLLNRKSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLSSSSSHSNQKKRPQSVIY 638          
BLAST of Cyclin-dependent kinase 16 vs. Planmine SMEST
Match: SMESG000023149.1 (SMESG000023149.1)

HSP 1 Score: 1112.83 bits (2877), Expect = 0.000e+0
Identity = 623/639 (97.50%), Postives = 623/639 (97.50%), Query Frame = 3
Query:   72 MMKDLKKRFSFSGKKNLNDKIESQIENLXXXXXXXXXXXXXXXXXXXXXXXYDSNPSQRNNSHMYGECNGSFNSNINSTSCAIYNQYHNPPVTSNNNHFHIAXXXXXXXXXXXXXXXXXXXNQCNGMSSYNENGCHXXXXXXXXXLLNHCRSNTDLVSQLTGPPNSSYNRSQSCSVSMAIGDHEEEAKDRFVVIEKGKCYVDGELVQGLSPSQLAQVRRRHRRPXXXXXXXXXXXXXXERGIDSSESDASKRLSLPANINLPPHLLNRKSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLXXXXXXXNQKKRPQSVIY 1988
            MMKDLKKRFSFSGKKNLNDKIESQIENLSIDSKNSNESNSNNYNNFQNGVSYDSNPSQRNNSHMYGECNGSFNSNINSTSCAIYNQYHNPPVTSNNNHFHIAVSHVPSSFGSSTTSSEIISNQCNGMSSYNENGCHSVSSSSASSLLNHCRSNTDLVSQLTGPPNSSYNRSQSCSVSMAIGDHEEEAKDRFVVIEKGKCYVDGELVQGLSPSQLAQVRRRHRRPGNSGVMSVSGGNGVERGIDSSESDASKR                KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLSSSSSHSNQKKRPQSVIY
Sbjct:    1 MMKDLKKRFSFSGKKNLNDKIESQIENLSIDSKNSNESNSNNYNNFQNGVSYDSNPSQRNNSHMYGECNGSFNSNINSTSCAIYNQYHNPPVTSNNNHFHIAVSHVPSSFGSSTTSSEIISNQCNGMSSYNENGCHSVSSSSASSLLNHCRSNTDLVSQLTGPPNSSYNRSQSCSVSMAIGDHEEEAKDRFVVIEKGKCYVDGELVQGLSPSQLAQVRRRHRRPGNSGVMSVSGGNGVERGIDSSESDASKR----------------KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLSSSSSHSNQKKRPQSVIY 623          
BLAST of Cyclin-dependent kinase 16 vs. Planmine SMEST
Match: SMESG000023149.1 (SMESG000023149.1)

HSP 1 Score: 1109.36 bits (2868), Expect = 0.000e+0
Identity = 622/638 (97.49%), Postives = 622/638 (97.49%), Query Frame = 3
Query:   75 MKDLKKRFSFSGKKNLNDKIESQIENLXXXXXXXXXXXXXXXXXXXXXXXYDSNPSQRNNSHMYGECNGSFNSNINSTSCAIYNQYHNPPVTSNNNHFHIAXXXXXXXXXXXXXXXXXXXNQCNGMSSYNENGCHXXXXXXXXXLLNHCRSNTDLVSQLTGPPNSSYNRSQSCSVSMAIGDHEEEAKDRFVVIEKGKCYVDGELVQGLSPSQLAQVRRRHRRPXXXXXXXXXXXXXXERGIDSSESDASKRLSLPANINLPPHLLNRKSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLXXXXXXXNQKKRPQSVIY 1988
            MKDLKKRFSFSGKKNLNDKIESQIENLSIDSKNSNESNSNNYNNFQNGVSYDSNPSQRNNSHMYGECNGSFNSNINSTSCAIYNQYHNPPVTSNNNHFHIAVSHVPSSFGSSTTSSEIISNQCNGMSSYNENGCHSVSSSSASSLLNHCRSNTDLVSQLTGPPNSSYNRSQSCSVSMAIGDHEEEAKDRFVVIEKGKCYVDGELVQGLSPSQLAQVRRRHRRPGNSGVMSVSGGNGVERGIDSSESDASKR                KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLSSSSSHSNQKKRPQSVIY
Sbjct:    1 MKDLKKRFSFSGKKNLNDKIESQIENLSIDSKNSNESNSNNYNNFQNGVSYDSNPSQRNNSHMYGECNGSFNSNINSTSCAIYNQYHNPPVTSNNNHFHIAVSHVPSSFGSSTTSSEIISNQCNGMSSYNENGCHSVSSSSASSLLNHCRSNTDLVSQLTGPPNSSYNRSQSCSVSMAIGDHEEEAKDRFVVIEKGKCYVDGELVQGLSPSQLAQVRRRHRRPGNSGVMSVSGGNGVERGIDSSESDASKR----------------KSQLLEPMTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQFTGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHLSVDPGSTRTVAHTRLSSSSSHSNQKKRPQSVIY 622          
BLAST of Cyclin-dependent kinase 16 vs. Planmine SMEST
Match: SMESG000048066.1 (SMESG000048066.1)

HSP 1 Score: 343.199 bits (879), Expect = 6.323e-108
Identity = 177/324 (54.63%), Postives = 223/324 (68.83%), Query Frame = 3
Query:  939 FGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPG-STVDEELQLIFKTLGVPSEATWPGISS---NKEFTSRQFNASESPQSLFNLVPRLQFT---GVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFDVPGVHL 1889
            FGK +SY KLD LG+G+YATVFKG S LT   VALKEIR+  EEG P TAIRE SLL+NL HAN+V LHDI+H  ++LT VFEY+H DL +Y+E   + +  +N+++FL+Q+LRGL +CH RRILHRDLKPQNLLI+ + G+LKLADFGLARAKS+P +TYSNEVVTLWYRPPDVLLGST+Y+  +DMWGVGCI  EM  G  +FPG    D++L+ IFK +G P+E  WPG+S+    + F   + N     + L   V RL FT     SL    L+ + + R+    AM H YF   S   + L  L    SVF VPGV +
Sbjct:  313 FGKSDSYQKLDMLGEGSYATVFKGYSNLTNQTVALKEIRINSEEGVPFTAIREASLLKNLRHANIVILHDIVHAKETLTFVFEYVHSDLSKYIERHPHGIKPHNIKLFLFQLLRGLGFCHERRILHRDLKPQNLLISEI-GELKLADFGLARAKSVPSRTYSNEVVTLWYRPPDVLLGSTDYNAALDMWGVGCIFVEMIGGSAIFPGLKDTDDQLEKIFKVMGSPNEKVWPGVSTLPNYQLFIMNRGNVCYKGRPLHRHVQRL-FTIPHAESLALAFLQIRPELRVLTRAAMSHPYFDDLS---KQLLYLPHNMSVFSVPGVRM 631          
BLAST of Cyclin-dependent kinase 16 vs. Planmine SMEST
Match: SMESG000050786.1 (SMESG000050786.1)

HSP 1 Score: 330.487 bits (846), Expect = 1.833e-106
Identity = 152/236 (64.41%), Postives = 192/236 (81.36%), Query Frame = 3
Query:  897 MTKKDRRYSLAEIGFGKLESYTKLDKLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLHHANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTYSNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVDEELQLIFKTLG 1604
            M+++ +R+SL+E GFGKLESY K + LG+GTY+TV+KG+S LT+  VALKE++LE  EGAPCTAIRE+SLLRNL H N+VTLHDII+    LTLVFEYL K+LKQYME+  N++ +  V+ F++Q+L GL +CH+R+ILHRDLKPQNLLIN  + +LKLADFGLARA+SIP K YSNEVVTLWYRPPD+LLG T+YS  ID+WG GCI  EM  G+ +FPG T D +L +IF+ LG
Sbjct:  189 MSRRQKRHSLSEFGFGKLESYNKYEILGKGTYSTVYKGQSLLTKDYVALKEVKLEEAEGAPCTAIREISLLRNLRHPNIVTLHDIIYQKNYLTLVFEYLEKNLKQYMEERNNLLELFIVKSFMFQLLSGLDFCHQRKILHRDLKPQNLLINE-KNELKLADFGLARAQSIPTKAYSNEVVTLWYRPPDLLLGKTDYSGHIDIWGAGCIFVEMLNGKALFPGHTDDHQLNIIFEKLG 423          
The following BLAST results are available for this feature:
BLAST of Cyclin-dependent kinase 16 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CDK171.872e-17267.65cyclin dependent kinase 17 [Source:HGNC Symbol;Acc... [more]
CDK172.402e-17267.65cyclin dependent kinase 17 [Source:HGNC Symbol;Acc... [more]
CDK173.399e-17267.65cyclin dependent kinase 17 [Source:HGNC Symbol;Acc... [more]
CDK168.718e-17265.57cyclin dependent kinase 16 [Source:HGNC Symbol;Acc... [more]
CDK163.479e-17165.57cyclin dependent kinase 16 [Source:HGNC Symbol;Acc... [more]
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BLAST of Cyclin-dependent kinase 16 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pct-15.813e-15562.77Cyclin-dependent kinase 17 [Source:UniProtKB/Swis... [more]
pct-11.463e-15462.77Cyclin-dependent kinase 17 [Source:UniProtKB/Swis... [more]
pct-11.463e-15462.77Cyclin-dependent kinase 17 [Source:UniProtKB/Swis... [more]
pct-11.463e-15462.77Cyclin-dependent kinase 17 [Source:UniProtKB/Swis... [more]
cdk-51.123e-9148.11Cyclin-dependent-like kinase 5 [Source:UniProtKB/... [more]
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BLAST of Cyclin-dependent kinase 16 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Eip63E6.719e-11755.03gene:FBgn0005640 transcript:FBtr0110922[more]
Eip63E8.226e-11755.03gene:FBgn0005640 transcript:FBtr0073134[more]
Eip63E8.226e-11755.03gene:FBgn0005640 transcript:FBtr0073133[more]
Eip63E8.226e-11755.03gene:FBgn0005640 transcript:FBtr0073135[more]
Eip63E8.226e-11755.03gene:FBgn0005640 transcript:FBtr0110924[more]
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BLAST of Cyclin-dependent kinase 16 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdk161.333e-17266.40cyclin-dependent kinase 16 [Source:ZFIN;Acc:ZDB-GE... [more]
cdk162.440e-17266.85cyclin-dependent kinase 16 [Source:ZFIN;Acc:ZDB-GE... [more]
CDK182.809e-17265.78si:dkey-166c18.1 [Source:ZFIN;Acc:ZDB-GENE-141215-... [more]
CDK182.809e-17265.78si:dkey-166c18.1 [Source:ZFIN;Acc:ZDB-GENE-141215-... [more]
cdk174.703e-17064.16cyclin-dependent kinase 17 [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of Cyclin-dependent kinase 16 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ambn3.821e-17460.45ameloblastin [Source:Xenbase;Acc:XB-GENE-853786][more]
ambn5.310e-17367.39ameloblastin [Source:Xenbase;Acc:XB-GENE-853786][more]
ambn1.391e-17267.39ameloblastin [Source:Xenbase;Acc:XB-GENE-853786][more]
ambn3.470e-17267.39ameloblastin [Source:Xenbase;Acc:XB-GENE-853786][more]
ambn2.727e-17171.81ameloblastin [Source:Xenbase;Acc:XB-GENE-853786][more]
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BLAST of Cyclin-dependent kinase 16 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cdk175.557e-17267.39cyclin-dependent kinase 17 [Source:MGI Symbol;Acc:... [more]
Cdk171.113e-17167.39cyclin-dependent kinase 17 [Source:MGI Symbol;Acc:... [more]
Cdk168.052e-17065.30cyclin-dependent kinase 16 [Source:MGI Symbol;Acc:... [more]
Cdk169.864e-17065.30cyclin-dependent kinase 16 [Source:MGI Symbol;Acc:... [more]
Cdk181.046e-16464.69cyclin-dependent kinase 18 [Source:MGI Symbol;Acc:... [more]
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BLAST of Cyclin-dependent kinase 16 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q00537|CDK17_HUMAN8.990e-17267.65Cyclin-dependent kinase 17 OS=Homo sapiens OX=9606... [more]
sp|Q8K0D0|CDK17_MOUSE7.782e-17167.39Cyclin-dependent kinase 17 OS=Mus musculus OX=1009... [more]
sp|Q00536|CDK16_HUMAN1.671e-17065.57Cyclin-dependent kinase 16 OS=Homo sapiens OX=9606... [more]
sp|O35831|CDK17_RAT1.970e-16967.12Cyclin-dependent kinase 17 OS=Rattus norvegicus OX... [more]
sp|O35832|CDK18_RAT4.791e-16965.50Cyclin-dependent kinase 18 OS=Rattus norvegicus OX... [more]
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BLAST of Cyclin-dependent kinase 16 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
L7LSQ22.555e-17769.04Putative cyclin-dependent kinase 16 OS=Rhipicephal... [more]
V4A6973.450e-17769.21Protein kinase domain-containing protein OS=Lottia... [more]
L7M1494.855e-17769.04Putative cyclin-dependent kinase 16 OS=Rhipicephal... [more]
A0A224YVZ05.068e-17769.04Cyclin dependent kinase 16 OS=Rhipicephalus zambez... [more]
A0A131YDM85.068e-17769.04Cyclin dependent kinase 16 OS=Rhipicephalus append... [more]
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BLAST of Cyclin-dependent kinase 16 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-166c18.12.419e-17365.43cyclin dependent kinase 18 [Source:NCBI gene;Acc:1... [more]
si:dkey-166c18.12.419e-17365.43cyclin dependent kinase 18 [Source:NCBI gene;Acc:1... [more]
cdk177.400e-17361.00cyclin dependent kinase 17 [Source:NCBI gene;Acc:1... [more]
cdk168.913e-17266.31cyclin-dependent kinase 16 [Source:ZFIN;Acc:ZDB-GE... [more]
ENSAMXT00000030743.11.730e-17164.12cyclin-dependent kinase 17-like [Source:NCBI gene;... [more]
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BLAST of Cyclin-dependent kinase 16 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000008013.12.139e-17070.50pep scaffold:Pmarinus_7.0:GL478839:10839:40406:1 g... [more]
cdk21.013e-9249.48cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
CDK171.583e-9161.78cyclin dependent kinase 17 [Source:HGNC Symbol;Acc... [more]
cdk22.404e-8947.40cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
ENSPMAT00000005451.16.537e-8650.66pep scaffold:Pmarinus_7.0:GL478132:187045:200874:-... [more]
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BLAST of Cyclin-dependent kinase 16 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
PHO851.133e-9448.99Cyclin-dependent kinase; has ten cyclin partners; ... [more]
CDC285.166e-8347.49Cyclin-dependent kinase (CDK) catalytic subunit; m... [more]
CTK11.377e-6140.00Catalytic (alpha) subunit of C-terminal domain kin... [more]
KIN286.946e-6137.19Serine/threonine protein kinase, subunit of transc... [more]
KSS17.198e-4634.08Mitogen-activated protein kinase (MAPK); involved ... [more]
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BLAST of Cyclin-dependent kinase 16 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO481174.753e-16369.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO438194.338e-10649.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO494203.875e-10452.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO414031.212e-9449.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO436712.098e-8344.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cyclin-dependent kinase 16 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000011316.21.508e-17563.91cyclin-dependent kinase 17 [Source:NCBI gene;Acc:1... [more]
ENSORLT00000011319.26.986e-17563.91cyclin-dependent kinase 17 [Source:NCBI gene;Acc:1... [more]
ENSORLT00000011315.21.860e-17466.22cyclin-dependent kinase 17 [Source:NCBI gene;Acc:1... [more]
ENSORLT00000036083.11.860e-17466.22cyclin-dependent kinase 17 [Source:NCBI gene;Acc:1... [more]
si:dkey-166c18.11.575e-17265.34cyclin dependent kinase 18 [Source:NCBI gene;Acc:1... [more]
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BLAST of Cyclin-dependent kinase 16 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000023149.10.000e+0100.00SMESG000023149.1[more]
SMESG000023149.10.000e+097.50SMESG000023149.1[more]
SMESG000023149.10.000e+097.49SMESG000023149.1[more]
SMESG000048066.16.323e-10854.63SMESG000048066.1[more]
SMESG000050786.11.833e-10664.41SMESG000050786.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30004031 ID=SMED30004031|Name=Cyclin-dependent kinase 16|organism=Schmidtea mediterranea sexual|type=transcript|length=2069bp
GTAAATTTAATATTATGATTTCTTATTCAACATAAGTTATATTCCAAAAC
GACTATTATTATCAGTTAAAAATGATGAAGGATCTAAAGAAACGATTTTC
ATTCTCAGGCAAGAAAAATCTGAATGATAAAATAGAATCACAAATTGAAA
ATCTATCAATCGATTCAAAAAATTCCAATGAGTCAAATTCTAATAATTAT
AATAACTTTCAGAATGGTGTATCATACGATTCAAATCCTTCACAGAGAAA
TAATTCACACATGTATGGAGAATGCAACGGGTCGTTCAACTCAAATATAA
ATAGTACTTCATGCGCAATATATAATCAGTACCACAATCCTCCAGTCACA
TCAAACAACAATCATTTCCATATAGCAGTTAGCCATGTTCCATCGTCGTT
CGGTTCATCAACTACGTCTTCGGAAATTATATCAAATCAGTGCAATGGAA
TGTCTTCATATAATGAAAACGGGTGTCATTCTGTTTCGTCTTCGTCTGCA
TCATCTCTTTTAAATCATTGTCGTTCCAATACAGATCTCGTTTCTCAATT
AACCGGTCCGCCAAATTCCTCATATAATCGCAGTCAATCCTGTTCAGTTT
CCATGGCCATAGGTGATCACGAAGAGGAAGCCAAGGACAGATTTGTTGTC
ATAGAAAAAGGCAAATGTTATGTCGATGGAGAATTGGTTCAAGGATTATC
TCCTTCTCAATTGGCACAAGTTAGGCGTAGACACCGCCGGCCTGGAAATT
CGGGTGTAATGTCAGTCAGTGGCGGCAATGGCGTTGAACGTGGAATAGAC
TCATCGGAATCCGACGCTAGTAAAAGGTTATCATTACCAGCTAATATCAA
TTTGCCTCCTCATTTACTCAATAGGAAAAGCCAATTACTAGAGCCAATGA
CAAAAAAAGATCGAAGATATTCATTGGCAGAAATCGGTTTTGGAAAATTG
GAATCCTACACAAAACTTGACAAATTGGGACAGGGAACTTATGCTACAGT
TTTCAAAGGTAGAAGCCGACTGACTGAATCGTTAGTTGCTTTAAAAGAAA
TAAGATTAGAGCATGAAGAAGGAGCTCCGTGTACAGCAATAAGAGAAGTG
TCTTTACTTAGAAATCTTCACCATGCAAATGTAGTTACTTTACACGATAT
TATTCACACTGTTAAATCATTAACGTTGGTATTTGAATATTTGCACAAAG
ATCTCAAGCAATACATGGAAGATTGTGCCAATATAATGAGCATGAATAAC
GTTCAAATATTTCTTTATCAAATTCTTCGTGGCCTGGCGTATTGTCATCG
TCGGAGAATACTTCATCGTGACCTCAAACCTCAGAACTTATTAATTAATC
CAGTGAGAGGGGACTTGAAGTTAGCAGATTTCGGTCTGGCTAGAGCAAAA
TCTATTCCAATCAAAACCTATTCCAATGAAGTGGTAACCTTATGGTATCG
GCCACCTGATGTGCTGCTCGGTTCTACCAATTATTCCACTCAAATCGATA
TGTGGGGTGTCGGTTGTATTTTATTTGAAATGGCTGCTGGTCGTCCTATG
TTTCCAGGATCAACAGTAGATGAAGAATTGCAACTTATTTTTAAAACCTT
AGGTGTACCTTCTGAAGCTACTTGGCCTGGTATTTCTTCCAATAAGGAAT
TTACTTCTCGTCAGTTCAATGCTAGTGAATCTCCACAGTCATTATTTAAT
CTAGTTCCGCGTCTCCAATTTACTGGTGTTTCTCTTTTAACCGGTTTACT
TGAATATCAAGGCAAAAAACGCATTTCAGCAGAAGACGCTATGCAACACG
ATTATTTTGTGCGTAGTTCACTGCCTGTCGAGGCATTGTCAAGGTTAAAG
GATACGGATAGCGTGTTTGATGTGCCTGGAGTTCATCTCAGCGTTGATCC
CGGTTCAACTAGAACTGTTGCTCATACTCGTCTCAGTAGCAGTTCCTCTC
ACTCAAACCAGAAAAAACGACCACAGAGTGTAATATACTGATCTGCCGAT
CAAATCCTATCAAAATTTGCATTAATCTTCGCTCTTTCTGTGCTGTTATT
GAAAGCAAATCATATATAA
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protein sequence of SMED30004031-orf-1

>SMED30004031-orf-1 ID=SMED30004031-orf-1|Name=SMED30004031-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=640bp
MMKDLKKRFSFSGKKNLNDKIESQIENLSIDSKNSNESNSNNYNNFQNGV
SYDSNPSQRNNSHMYGECNGSFNSNINSTSCAIYNQYHNPPVTSNNNHFH
IAVSHVPSSFGSSTTSSEIISNQCNGMSSYNENGCHSVSSSSASSLLNHC
RSNTDLVSQLTGPPNSSYNRSQSCSVSMAIGDHEEEAKDRFVVIEKGKCY
VDGELVQGLSPSQLAQVRRRHRRPGNSGVMSVSGGNGVERGIDSSESDAS
KRLSLPANINLPPHLLNRKSQLLEPMTKKDRRYSLAEIGFGKLESYTKLD
KLGQGTYATVFKGRSRLTESLVALKEIRLEHEEGAPCTAIREVSLLRNLH
HANVVTLHDIIHTVKSLTLVFEYLHKDLKQYMEDCANIMSMNNVQIFLYQ
ILRGLAYCHRRRILHRDLKPQNLLINPVRGDLKLADFGLARAKSIPIKTY
SNEVVTLWYRPPDVLLGSTNYSTQIDMWGVGCILFEMAAGRPMFPGSTVD
EELQLIFKTLGVPSEATWPGISSNKEFTSRQFNASESPQSLFNLVPRLQF
TGVSLLTGLLEYQGKKRISAEDAMQHDYFVRSSLPVEALSRLKDTDSVFD
VPGVHLSVDPGSTRTVAHTRLSSSSSHSNQKKRPQSVIY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR008271Ser/Thr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0005515protein binding
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 296..579
e-value: 3.0E-88
score: 309.1
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 296..579
e-value: 4.7E-67
score: 226.1
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 296..579
score: 43.029
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 376..599
e-value: 1.3E-65
score: 223.1
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 293..375
e-value: 2.2E-32
score: 112.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 619..639
NoneNo IPR availablePANTHERPTHR24056:SF128CYCLIN-DEPENDENT KINASE 17coord: 249..615
NoneNo IPR availablePANTHERPTHR24056CELL DIVISION PROTEIN KINASEcoord: 249..615
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 413..425
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 302..325
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 289..581