RRM domain-containing protein

Overview
NameRRM domain-containing protein
Smed IDSMED30003989
Length (bp)1268
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of RRM domain-containing protein (SMED30003989) t-SNE clustered cells

Violin plots show distribution of expression levels for RRM domain-containing protein (SMED30003989) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RRM domain-containing protein (SMED30003989) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RRM domain-containing protein (SMED30003989) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30003989

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30003989h1SMcG0012918 SmedASXL_019196SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30003989h1SMcG0012918 SmedASXL_019196SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30003989h1SMcG0012918 Contig48371newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30003989h1SMcG0012918 Contig48371uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30003989h1SMcG0012918 dd_Smed_v4_3781_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30003989h1SMcG0012918 dd_Smed_v4_3781_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003989h1SMcG0012918 dd_Smed_v4_3781_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003989h1SMcG0012918 dd_Smed_v4_3781_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of RRM domain-containing protein vs. Ensembl Human
Match: TRA2B (transformer 2 beta homolog [Source:HGNC Symbol;Acc:HGNC:10781])

HSP 1 Score: 82.8037 bits (203), Expect = 6.486e-18
Identity = 36/89 (40.45%), Postives = 59/89 (66.29%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPAS 630
            N +P  C+G+FGLS  T E  L + F KYG I +V ++ D+  R S G+AF+ ++ ++ A +A + A+G E+DG  IR+D+S+ K+P +
Sbjct:   13 NPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRPHT 101          
BLAST of RRM domain-containing protein vs. Ensembl Human
Match: TRA2B (transformer 2 beta homolog [Source:HGNC Symbol;Acc:HGNC:10781])

HSP 1 Score: 83.5741 bits (205), Expect = 2.476e-17
Identity = 36/87 (41.38%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P  C+G+FGLS  T E  L + F KYG I +V ++ D+  R S G+AF+ ++ ++ A +A + A+G E+DG  IR+D+S+ K+P
Sbjct:  113 NPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRP 199          
BLAST of RRM domain-containing protein vs. Ensembl Human
Match: TRA2A (transformer 2 alpha homolog [Source:HGNC Symbol;Acc:HGNC:16645])

HSP 1 Score: 79.7221 bits (195), Expect = 7.054e-17
Identity = 35/86 (40.70%), Postives = 57/86 (66.28%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ + +AM+ A+G E+DG  IR+DYS+ K+
Sbjct:   13 NPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKR 98          
BLAST of RRM domain-containing protein vs. Ensembl Human
Match: TRA2A (transformer 2 alpha homolog [Source:HGNC Symbol;Acc:HGNC:16645])

HSP 1 Score: 79.7221 bits (195), Expect = 7.212e-17
Identity = 35/86 (40.70%), Postives = 57/86 (66.28%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ + +AM+ A+G E+DG  IR+DYS+ K+
Sbjct:   13 NPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKR 98          
BLAST of RRM domain-containing protein vs. Ensembl Human
Match: TRA2A (transformer 2 alpha homolog [Source:HGNC Symbol;Acc:HGNC:16645])

HSP 1 Score: 79.7221 bits (195), Expect = 7.212e-17
Identity = 35/86 (40.70%), Postives = 57/86 (66.28%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ + +AM+ A+G E+DG  IR+DYS+ K+
Sbjct:   13 NPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKR 98          
BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: rsp-8 (SR Protein (Splicing factor) [Source:UniProtKB/TrEMBL;Acc:G3MU77])

HSP 1 Score: 71.2478 bits (173), Expect = 1.492e-13
Identity = 34/87 (39.08%), Postives = 53/87 (60.92%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            EN +P  C+G+F LS  T E+ L D F ++G+I+   L+ DR    S G+ FI +  IE A  A  +   T++DG+ IR+D+S+ K+
Sbjct:   70 ENPQPSKCLGVFNLSSYTTEKDLRDVFGEFGEINKCDLVYDRPSGNSRGFGFIYFNLIEDATAARDKLCNTDLDGHKIRVDFSLTKR 156          
BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: rsp-8 (SR Protein (Splicing factor) [Source:UniProtKB/TrEMBL;Acc:G3MU77])

HSP 1 Score: 71.2478 bits (173), Expect = 1.492e-13
Identity = 34/87 (39.08%), Postives = 53/87 (60.92%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            EN +P  C+G+F LS  T E+ L D F ++G+I+   L+ DR    S G+ FI +  IE A  A  +   T++DG+ IR+D+S+ K+
Sbjct:   70 ENPQPSKCLGVFNLSSYTTEKDLRDVFGEFGEINKCDLVYDRPSGNSRGFGFIYFNLIEDATAARDKLCNTDLDGHKIRVDFSLTKR 156          
BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: rbm-3.1 (RNA Binding Motif protein homolog [Source:UniProtKB/TrEMBL;Acc:O45712])

HSP 1 Score: 48.1358 bits (113), Expect = 3.117e-7
Identity = 23/67 (34.33%), Postives = 42/67 (62.69%), Query Frame = 1
Query:  409 KTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYS 609
            +T EE L + F   G+I+NVR++ DR      G+AFI++ E   A +A+++ +G E +G  +R++ +
Sbjct:   15 QTTEEELGNFFSSIGQINNVRIVCDRETGRPRGFAFIEFAEEGSAQRAVEQMNGAEFNGRPLRVNLA 81          
BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: rnp-4 (RNA-binding protein 8A [Source:UniProtKB/TrEMBL;Acc:Q21832])

HSP 1 Score: 49.2914 bits (116), Expect = 4.442e-7
Identity = 26/87 (29.89%), Postives = 52/87 (59.77%), Query Frame = 1
Query:  382 CIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSV--GKKPASTR 636
             + +  + ++  E+ + DKF +YGKI N+ L +DR      GYA ++Y+  + A +A+ +++ T++ G N+++D+    GKK +  R
Sbjct:   56 IVFVTNIHEEATEDDVHDKFSEYGKIKNIHLNLDRRTGFLKGYALVEYETQKEANEAIDQSNDTDLLGQNVKVDWCFVKGKKTSGKR 142          
BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: rnp-4 (RNA-binding protein 8A [Source:UniProtKB/TrEMBL;Acc:Q21832])

HSP 1 Score: 49.2914 bits (116), Expect = 4.442e-7
Identity = 26/87 (29.89%), Postives = 52/87 (59.77%), Query Frame = 1
Query:  382 CIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSV--GKKPASTR 636
             + +  + ++  E+ + DKF +YGKI N+ L +DR      GYA ++Y+  + A +A+ +++ T++ G N+++D+    GKK +  R
Sbjct:   56 IVFVTNIHEEATEDDVHDKFSEYGKIKNIHLNLDRRTGFLKGYALVEYETQKEANEAIDQSNDTDLLGQNVKVDWCFVKGKKTSGKR 142          
BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089616)

HSP 1 Score: 74.7146 bits (182), Expect = 1.861e-15
Identity = 41/140 (29.29%), Postives = 71/140 (50.71%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSV------------------GKKPAS------TRFFKDTASTPYNRYDSK--YRNNGY 702
            E+ +   CIG+FGL+  T +  + + F KYG I+ +++++D   + S G+ FI ++++  A  A     G E+DG  IR+D+S+                  GK P S       R + D +++PY+ Y  +  YRN+ Y
Sbjct:    6 EHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAHTPTPGVYLGRQPRGKAPRSFSPRRGRRVYHDRSASPYDNYRDRYDYRNDRY 145          
BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089615)

HSP 1 Score: 74.7146 bits (182), Expect = 4.208e-15
Identity = 41/140 (29.29%), Postives = 71/140 (50.71%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSV------------------GKKPAS------TRFFKDTASTPYNRYDSK--YRNNGY 702
            E+ +   CIG+FGL+  T +  + + F KYG I+ +++++D   + S G+ FI ++++  A  A     G E+DG  IR+D+S+                  GK P S       R + D +++PY+ Y  +  YRN+ Y
Sbjct:   53 EHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAHTPTPGVYLGRQPRGKAPRSFSPRRGRRVYHDRSASPYDNYRDRYDYRNDRY 192          
BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089619)

HSP 1 Score: 74.7146 bits (182), Expect = 4.208e-15
Identity = 41/140 (29.29%), Postives = 71/140 (50.71%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSV------------------GKKPAS------TRFFKDTASTPYNRYDSK--YRNNGY 702
            E+ +   CIG+FGL+  T +  + + F KYG I+ +++++D   + S G+ FI ++++  A  A     G E+DG  IR+D+S+                  GK P S       R + D +++PY+ Y  +  YRN+ Y
Sbjct:   53 EHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAHTPTPGVYLGRQPRGKAPRSFSPRRGRRVYHDRSASPYDNYRDRYDYRNDRY 192          
BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089620)

HSP 1 Score: 74.7146 bits (182), Expect = 6.943e-15
Identity = 41/140 (29.29%), Postives = 71/140 (50.71%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSV------------------GKKPAS------TRFFKDTASTPYNRYDSK--YRNNGY 702
            E+ +   CIG+FGL+  T +  + + F KYG I+ +++++D   + S G+ FI ++++  A  A     G E+DG  IR+D+S+                  GK P S       R + D +++PY+ Y  +  YRN+ Y
Sbjct:   91 EHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAHTPTPGVYLGRQPRGKAPRSFSPRRGRRVYHDRSASPYDNYRDRYDYRNDRY 230          
BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089621)

HSP 1 Score: 74.7146 bits (182), Expect = 6.943e-15
Identity = 41/140 (29.29%), Postives = 71/140 (50.71%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSV------------------GKKPAS------TRFFKDTASTPYNRYDSK--YRNNGY 702
            E+ +   CIG+FGL+  T +  + + F KYG I+ +++++D   + S G+ FI ++++  A  A     G E+DG  IR+D+S+                  GK P S       R + D +++PY+ Y  +  YRN+ Y
Sbjct:   91 EHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAHTPTPGVYLGRQPRGKAPRSFSPRRGRRVYHDRSASPYDNYRDRYDYRNDRY 230          
BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 83.5741 bits (205), Expect = 2.645e-18
Identity = 37/87 (42.53%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ A +AM+ A+G E+DG  IR+DYS+ K+P
Sbjct:  101 NPDPNTCLGVFGLSLYTTERDLREVFSRYGSLAGVNVVYDQRTGRSRGFAFVYFEHIDDAKEAMERANGMELDGRRIRVDYSITKRP 187          
BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 83.5741 bits (205), Expect = 2.645e-18
Identity = 37/87 (42.53%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ A +AM+ A+G E+DG  IR+DYS+ K+P
Sbjct:  101 NPDPNTCLGVFGLSLYTTERDLREVFSRYGSLAGVNVVYDQRTGRSRGFAFVYFEHIDDAKEAMERANGMELDGRRIRVDYSITKRP 187          
BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 84.3445 bits (207), Expect = 8.473e-18
Identity = 37/87 (42.53%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ A +AM+ A+G E+DG  IR+DYS+ K+P
Sbjct:  130 NPDPNTCLGVFGLSLYTTERDLREVFSRYGSLAGVNVVYDQRTGRSRGFAFVYFEHIDDAKEAMERANGMELDGRRIRVDYSITKRP 216          
BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 83.9593 bits (206), Expect = 1.176e-17
Identity = 37/87 (42.53%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ A +AM+ A+G E+DG  IR+DYS+ K+P
Sbjct:  130 NPDPNTCLGVFGLSLYTTERDLREVFSRYGSLAGVNVVYDQRTGRSRGFAFVYFEHIDDAKEAMERANGMELDGRRIRVDYSITKRP 216          
BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: tra2b (transformer 2 beta homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1094])

HSP 1 Score: 80.4925 bits (197), Expect = 1.225e-16
Identity = 36/87 (41.38%), Postives = 57/87 (65.52%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P  C+G+FGLS  T E  L + F KYG + +V ++ D+  R S G+AF+ ++  E + +A + A+G E+DG  IR+DYS+ K+P
Sbjct:  118 NPDPNCCLGVFGLSLYTTERDLREVFSKYGPLSDVCIVYDQQSRRSRGFAFVYFENREDSKEAKERANGMELDGRRIRVDYSITKRP 204          
BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: rit1 (Ras-like without CAAX 1 [Source:Xenbase;Acc:XB-GENE-5777077])

HSP 1 Score: 82.8037 bits (203), Expect = 6.103e-17
Identity = 35/87 (40.23%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P  C+G+FGLS  T E  L + F KYG I +V ++ D+  R S G++F+ ++ ++ A +A + A+G E+DG  IR+D+S+ K+P
Sbjct:  148 NPDPNCCLGVFGLSLYTTERDLREVFSKYGPISDVSIVYDQQSRRSRGFSFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRP 234          
BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: plekhg5 (pleckstrin homology and RhoGEF domain containing G5 [Source:Xenbase;Acc:XB-GENE-6039487])

HSP 1 Score: 81.2629 bits (199), Expect = 1.344e-16
Identity = 36/86 (41.86%), Postives = 56/86 (65.12%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            N +P  CIG+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ IE + +AM+ A+G E+DG  IR+DYS+ K+
Sbjct:  109 NPDPNICIGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIEDSREAMEHANGMELDGRRIRVDYSITKR 194          
BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: cirbp (cold inducible RNA binding protein [Source:NCBI gene;Acc:549982])

HSP 1 Score: 54.299 bits (129), Expect = 4.017e-8
Identity = 26/71 (36.62%), Postives = 42/71 (59.15%), Query Frame = 1
Query:  391 IFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLD 603
            + GL+ +T EE+L   F KYG++  V ++ DR  + S G+ F+ ++  E A  AM   +G  +DG  IR+D
Sbjct:   10 VGGLNFETTEESLEQVFSKYGQVAEVVVVKDRESKRSRGFGFVTFENPEDAKDAMMAMNGKSVDGRQIRVD 80          
BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: cirbp (cold inducible RNA binding protein [Source:NCBI gene;Acc:549982])

HSP 1 Score: 53.9138 bits (128), Expect = 4.712e-8
Identity = 26/71 (36.62%), Postives = 42/71 (59.15%), Query Frame = 1
Query:  391 IFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLD 603
            + GL+ +T EE+L   F KYG++  V ++ DR  + S G+ F+ ++  E A  AM   +G  +DG  IR+D
Sbjct:   22 VGGLNFETTEESLEQVFSKYGQVAEVVVVKDRESKRSRGFGFVTFENPEDAKDAMMAMNGKSVDGRQIRVD 92          
BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: adat1 (adenosine deaminase, tRNA-specific 1 [Source:Xenbase;Acc:XB-GENE-1002540])

HSP 1 Score: 55.4546 bits (132), Expect = 5.166e-8
Identity = 30/82 (36.59%), Postives = 47/82 (57.32%), Query Frame = 1
Query:  367 AEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSV 612
             +P   + +  LS++T EE L + F +YG I  +RL+ D     S GYAFI+YK+    MKA ++A+   ID   I +D+ +
Sbjct:   47 GDPHLTLYVARLSQQTTEEKLKEVFSRYGDIKRIRLVRDFITGFSKGYAFIEYKQENAIMKAHRDANKLVIDQREIFVDFEL 128          
BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Tra2b (transformer 2 beta [Source:MGI Symbol;Acc:MGI:106016])

HSP 1 Score: 82.8037 bits (203), Expect = 4.453e-18
Identity = 36/89 (40.45%), Postives = 59/89 (66.29%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPAS 630
            N +P  C+G+FGLS  T E  L + F KYG I +V ++ D+  R S G+AF+ ++ ++ A +A + A+G E+DG  IR+D+S+ K+P +
Sbjct:   13 NPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRPHT 101          
BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Tra2b (transformer 2 beta [Source:MGI Symbol;Acc:MGI:106016])

HSP 1 Score: 83.5741 bits (205), Expect = 1.700e-17
Identity = 36/87 (41.38%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P  C+G+FGLS  T E  L + F KYG I +V ++ D+  R S G+AF+ ++ ++ A +A + A+G E+DG  IR+D+S+ K+P
Sbjct:  113 NPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRP 199          
BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Tra2a (transformer 2 alpha [Source:MGI Symbol;Acc:MGI:1933972])

HSP 1 Score: 80.4925 bits (197), Expect = 1.709e-16
Identity = 35/86 (40.70%), Postives = 57/86 (66.28%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ + +AM+ A+G E+DG  IR+DYS+ K+
Sbjct:  112 NPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKR 197          
BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Tra2a (transformer 2 alpha [Source:MGI Symbol;Acc:MGI:1933972])

HSP 1 Score: 80.4925 bits (197), Expect = 1.756e-16
Identity = 35/86 (40.70%), Postives = 57/86 (66.28%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ + +AM+ A+G E+DG  IR+DYS+ K+
Sbjct:  112 NPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKR 197          
BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Snrnp35 (small nuclear ribonucleoprotein 35 (U11/U12) [Source:MGI Symbol;Acc:MGI:1923417])

HSP 1 Score: 60.4622 bits (145), Expect = 5.813e-10
Identity = 34/86 (39.53%), Postives = 49/86 (56.98%), Query Frame = 1
Query:  355 KNENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSV 612
            K    +P   + +  L+ +TKEE L + F +YG I  +RL+ D     S GYAFI+YKE    MKA ++A G  ID + I +DY +
Sbjct:   43 KGVTGDPLLTLFVARLNLQTKEEKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKEERALMKAYRDADGLVIDQHEIFVDYEL 128          
BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|P62997|TRA2B_RAT (Transformer-2 protein homolog beta OS=Rattus norvegicus OX=10116 GN=Tra2b PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.189e-16
Identity = 36/87 (41.38%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P  C+G+FGLS  T E  L + F KYG I +V ++ D+  R S G+AF+ ++ ++ A +A + A+G E+DG  IR+D+S+ K+P
Sbjct:  113 NPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRP 199          
BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|P62996|TRA2B_MOUSE (Transformer-2 protein homolog beta OS=Mus musculus OX=10090 GN=Tra2b PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.189e-16
Identity = 36/87 (41.38%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P  C+G+FGLS  T E  L + F KYG I +V ++ D+  R S G+AF+ ++ ++ A +A + A+G E+DG  IR+D+S+ K+P
Sbjct:  113 NPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRP 199          
BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|P62995|TRA2B_HUMAN (Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.189e-16
Identity = 36/87 (41.38%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P  C+G+FGLS  T E  L + F KYG I +V ++ D+  R S G+AF+ ++ ++ A +A + A+G E+DG  IR+D+S+ K+P
Sbjct:  113 NPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRP 199          
BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3ZBT6|TRA2B_BOVIN (Transformer-2 protein homolog beta OS=Bos taurus OX=9913 GN=TRA2B PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.189e-16
Identity = 36/87 (41.38%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P  C+G+FGLS  T E  L + F KYG I +V ++ D+  R S G+AF+ ++ ++ A +A + A+G E+DG  IR+D+S+ K+P
Sbjct:  113 NPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRP 199          
BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6PFR5|TRA2A_MOUSE (Transformer-2 protein homolog alpha OS=Mus musculus OX=10090 GN=Tra2a PE=1 SV=1)

HSP 1 Score: 80.4925 bits (197), Expect = 1.212e-15
Identity = 35/86 (40.70%), Postives = 57/86 (66.28%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ + +AM+ A+G E+DG  IR+DYS+ K+
Sbjct:  112 NPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKR 197          
BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A1S6KMI2 (RRM domain-containing protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 8.160e-21
Identity = 43/83 (51.81%), Postives = 64/83 (77.11%), Query Frame = 1
Query:  373 PCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            P   +GIFGLS+KT E+ LW  F+KYGKI++++L+M+R   ES GY+FI+Y++I+ A++A+KE  G  +DG  IR+DYS GK+
Sbjct:  153 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKR 235          
BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A0K0G166 (Transformer-2 sex-determining protein (inferred by orthology to a D. melanogaster protein) OS=Strongyloides venezuelensis OX=75913 PE=4 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 8.726e-18
Identity = 45/88 (51.14%), Postives = 59/88 (67.05%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            E AEP  CIG+FG+S +TK+E L   F K+G I+ V ++ D     S GY FI +K+IE A+KA  E +G EIDG N+R+DYSV K P
Sbjct:   91 EPAEPSRCIGVFGMSTRTKDEDLESVFSKFGAIEKVTIVKDSPTGCSRGYGFIYFKDIEDAIKAKNEMNGQEIDGRNVRVDYSVTKGP 178          
BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A0N5BMA3 (RRM domain-containing protein OS=Strongyloides papillosus OX=174720 PE=4 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 8.726e-18
Identity = 45/88 (51.14%), Postives = 59/88 (67.05%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            E AEP  CIG+FG+S +TK+E L   F K+G I+ V ++ D     S GY FI +K+IE A+KA  E +G EIDG N+R+DYSV K P
Sbjct:   91 EPAEPSRCIGVFGMSTRTKDEDLESVFSKFGAIEKVTIVKDSPTGCSRGYGFIYFKDIEDAIKAKNEMNGQEIDGRNVRVDYSVTKGP 178          
BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A4S2L5X9 (RRM domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_010251 PE=4 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 1.164e-17
Identity = 41/90 (45.56%), Postives = 57/90 (63.33%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPAS 630
            ENA+P  C+G+FGLS  T+E  L+D F +YG ID+V+L+ D     S G+ F+ +  +  A  A  EAHG E+DG  IR D+SV  +P S
Sbjct:   69 ENAKPSRCLGVFGLSLHTQERDLYDIFSRYGPIDDVQLVYDNYTGRSRGFGFVYFNHLSDAKVAKSEAHGMEVDGRPIRCDFSVTDRPHS 158          
BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A074ZLA8 (RRM domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_06215 PE=4 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 1.360e-17
Identity = 41/90 (45.56%), Postives = 57/90 (63.33%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPAS 630
            ENA+P  C+G+FGLS  T+E  L+D F +YG ID+V+L+ D     S G+ F+ +  +  A  A  EAHG E+DG  IR D+SV  +P S
Sbjct:   68 ENAKPSRCLGVFGLSLHTQERDLYDIFSRYGPIDDVQLVYDNYTGRSRGFGFVYFNHLSDAKVAKSEAHGMEVDGRPIRCDFSVTDRPHS 157          
BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 83.1889 bits (204), Expect = 6.096e-18
Identity = 36/87 (41.38%), Postives = 58/87 (66.67%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ + +AM+ A+G E+DG  IR+DYS+ K+P
Sbjct:  130 NPDPNTCLGVFGLSLYTTERDLREVFSRYGPLAGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRP 216          
BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 83.1889 bits (204), Expect = 8.423e-18
Identity = 36/89 (40.45%), Postives = 59/89 (66.29%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPAS 630
            N +P TC+G+FGLS  T E  L + F +YG +  V ++ D+    S G+AF+ ++ I+ + +AM+ A+G E+DG  IR+DYS+ K+P +
Sbjct:  102 NPDPNTCLGVFGLSLYTTERDLREVFSRYGPLAGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRPHT 190          
BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000034164.1 (pep primary_assembly:Astyanax_mexicanus-2.0:12:6544829:6548035:1 gene:ENSAMXG00000039469.1 transcript:ENSAMXT00000034164.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 80.4925 bits (197), Expect = 1.714e-17
Identity = 35/89 (39.33%), Postives = 58/89 (65.17%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPAS 630
            N +P  C+G+FGLS  T E  L + F KYG + +V ++ D+  R S G+AF+ ++  E + +A + A+G E+DG  IR+DYS+ ++P +
Sbjct:   13 NPDPNCCLGVFGLSLYTTERDLREVFSKYGPLSSVSIVYDQQSRRSRGFAFVYFENREDSREAKERANGMELDGRRIRVDYSITQRPHT 101          
BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: tra2b (transformer-2 protein homolog alpha-like [Source:NCBI gene;Acc:103029311])

HSP 1 Score: 80.1073 bits (196), Expect = 1.733e-16
Identity = 35/89 (39.33%), Postives = 58/89 (65.17%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPAS 630
            N +P  C+G+FGLS  T E  L + F KYG + +V ++ D+  R S G+AF+ ++  E + +A + A+G E+DG  IR+D+S+ K+P +
Sbjct:  113 NPDPTCCLGVFGLSLYTTERDLREVFSKYGPLADVCIVYDQQSRRSRGFAFVYFENREDSQEAKERANGMELDGRRIRVDFSITKRPHT 201          
BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: cirbpb (cold inducible RNA binding protein b [Source:ZFIN;Acc:ZDB-GENE-030131-5841])

HSP 1 Score: 55.0694 bits (131), Expect = 2.005e-8
Identity = 30/71 (42.25%), Postives = 40/71 (56.34%), Query Frame = 1
Query:  391 IFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLD 603
            I GLS  T E++L D F KYG I  V +I DR    S G+ F+ ++  + A  AM   +G  IDG  IR+D
Sbjct:   48 IGGLSYDTTEQSLEDAFSKYGTIAKVDVIRDRETDRSRGFGFVTFENPDDAKDAMVAMNGKSIDGRMIRVD 118          
BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: tra2b (transformer 2 beta homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1094])

HSP 1 Score: 75.485 bits (184), Expect = 1.377e-15
Identity = 33/86 (38.37%), Postives = 55/86 (63.95%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            N EP TC+G+FGLS  T E  L + F +YG + +V ++ D+      G+AF+  + +E + +A +  +G E+DG NIR+D+S+ K+
Sbjct:  101 NPEPNTCLGVFGLSLYTTEHDLREVFGRYGPVADVNVVYDQQSGRPRGFAFVYMQNMEDSKEAKERVNGMELDGRNIRVDFSITKR 186          
BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 74.7146 bits (182), Expect = 2.060e-15
Identity = 33/86 (38.37%), Postives = 55/86 (63.95%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            N +P  C+G+FGLS  T E+ L + F +YG + +V ++ D+    S G+AF+ +   E A +A + A+G E+DG  IR+D+S+ K+
Sbjct:  107 NPDPSCCLGVFGLSLHTGEKDLKEVFSRYGPVQSVNVVYDQQSGRSRGFAFVYFDNSEDAKEAKERANGMELDGRYIRVDFSITKR 192          
BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: srsf2b (serine and arginine rich splicing factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-2420])

HSP 1 Score: 55.8398 bits (133), Expect = 2.290e-9
Identity = 30/96 (31.25%), Postives = 48/96 (50.00%), Query Frame = 1
Query:  367 AEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPASTRFFKDTA 654
            + P   + +  L+ +T  E L   FEKYG + +V +  DR  RES G+AF+ + +   A  AM    G  +DG  +R+  +   +PA   F +  A
Sbjct:    4 SRPSRALQVDNLTYRTSPEMLRRSFEKYGDVGDVYIPRDRFTRESRGFAFVRFYDKRDAEDAMDAMDGKMLDGRELRVQVARYSRPADPYFQRRAA 99          
BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002832.1 (pep scaffold:Pmarinus_7.0:GL476732:699988:701739:-1 gene:ENSPMAG00000002585.1 transcript:ENSPMAT00000002832.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.9878 bits (123), Expect = 9.731e-9
Identity = 25/78 (32.05%), Postives = 47/78 (60.26%), Query Frame = 1
Query:  391 IFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            + G+ ++ +E+ + DKF ++G+I NV L +DR      GYA ++Y+  + A  AM+  +G +I G  I +D++  + P
Sbjct:   14 VTGVHEEAQEDDMHDKFGEFGEIKNVHLNLDRRTGFLKGYALVEYETFKEAQAAMEGLNGADILGQKIAVDWAFVRGP 91          
BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: ncl (nucleolin [Source:ZFIN;Acc:ZDB-GENE-030131-6986])

HSP 1 Score: 53.9138 bits (128), Expect = 4.183e-8
Identity = 27/81 (33.33%), Postives = 45/81 (55.56%), Query Frame = 1
Query:  367 AEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYS 609
            +E  + + + GL + T E+TL D FE        R++ DR   +S GYA++D+   + A  A+    G EIDG+ I +D++
Sbjct:  541 SEASSTLFVRGLGEDTSEDTLMDSFEG---ATAARIVTDRDSGQSKGYAYVDFSSADEAKSALNAMKGVEIDGSQIYVDFA 618          

HSP 2 Score: 52.7582 bits (125), Expect = 1.009e-7
Identity = 35/104 (33.65%), Postives = 54/104 (51.92%), Query Frame = 1
Query:  346 NRMKNENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSV-----GKKPASTRFF 642
            N+ K +  E  T + +  LS +  E++L   FE     + VR++MDR   +  G AF+D+  I+ A  AMK   G E++G  IRL++S      G   AS+  F
Sbjct:  449 NKAKPQGPESNTLM-VRNLSFQADEDSLRSVFEN---AEAVRVLMDRETGKPRGMAFVDFASIDDAKAAMKAHSGAEVEGRAIRLEFSTPRGTPGPSEASSTLF 548          
BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: NSR1 (Nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis; binds to single stranded telomeric DNA and mRNA; methylated by Hmt1p; interaction with Top1p and nucleolar localization are negatively regulated by polyphosphorylation [Source:SGD;Acc:S000003391])

HSP 1 Score: 62.7734 bits (151), Expect = 3.133e-11
Identity = 40/109 (36.70%), Postives = 55/109 (50.46%), Query Frame = 1
Query:  349 RMKNENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPAS----TRFFKDTASTP 663
            + KNE  E    I +  LS    +E L  +FE  G +   R+I +RG   S GY ++D++   +A KA++E  G EIDG  I  D S   KPA      + F DT S P
Sbjct:  158 KQKNEETEEPATIFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTS-KPAGNNDRAKKFGDTPSEP 265          
BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: RIE1 (Putative RNA binding protein; localizes to stress granules induced by glucose deprivation; interacts with Rbg1p in a two-hybrid assay; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003482])

HSP 1 Score: 45.8246 bits (107), Expect = 9.272e-6
Identity = 27/79 (34.18%), Postives = 43/79 (54.43%), Query Frame = 1
Query:  385 IGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            I + G++K      L   F KYG I +++LI D+ K E  GY FI Y     A   +KE +G  ++G+ + ++Y V +K
Sbjct:  197 IFVGGIAKSLSIGELSFLFSKYGPILSMKLIYDKTKGEPNGYGFISYPLGSQASLCIKELNGRTVNGSTLFINYHVERK 275          
BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO44802 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUS7])

HSP 1 Score: 74.7146 bits (182), Expect = 8.727e-16
Identity = 34/87 (39.08%), Postives = 52/87 (59.77%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            +N  P  C+G+FGLS  T E  L   FEKYG ++ ++++ D     S G+ F+ Y++ + A  A +   G E+DG  IR+DYSV K+
Sbjct:   89 DNPSPSRCLGVFGLSLYTTERDLRPVFEKYGPVEAIQIVYDHQTGRSRGFGFVYYEDTKDAEVAKERTTGIELDGRRIRVDYSVTKR 175          
BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO42298 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1T6])

HSP 1 Score: 58.151 bits (139), Expect = 1.103e-9
Identity = 33/81 (40.74%), Postives = 48/81 (59.26%), Query Frame = 1
Query:  376 CTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGK 618
            CT   I  LSK+T+ ETL + F KYG+++N RL+ D     S GYAF+++KE   A  A +E     IDG  I +++  G+
Sbjct:   54 CTLF-IGRLSKETRAETLVEAFSKYGEVENCRLVRDFVTGFSRGYAFVEFKERWDAKTAYREISKCCIDGQEILVEFEAGR 133          
BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO38445 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCR4])

HSP 1 Score: 57.3806 bits (137), Expect = 6.427e-9
Identity = 28/79 (35.44%), Postives = 44/79 (55.70%), Query Frame = 1
Query:  373 PCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYS 609
            P + + +  LS  T  ++L   FE      N ++I DR   ES G+ F+DY ++E A K + E  G E+DG  +RLD++
Sbjct:  475 PNSSLIVRNLSYDTTTDSLGAAFEG---CSNAKVIFDRESGESRGFGFVDYDDVETAKKVLSEMAGAEVDGRQVRLDFA 550          
BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO36522 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF0])

HSP 1 Score: 48.521 bits (114), Expect = 8.335e-7
Identity = 28/92 (30.43%), Postives = 50/92 (54.35%), Query Frame = 1
Query:  346 NRMKNENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFI---DYKEIEFAMKAMKEAHGTEIDGNNIRLDYSV 612
            NR +N N +P   + + GL+++T  ETL + FE YG++ +V +I D   ++S G+ ++   DYK     +K   E     IDG  + +  ++
Sbjct:    3 NRQENTNNDPRAKLFVGGLNRETTNETLREYFEAYGELTDVVVICDSATKKSRGFGYVTFADYKVTRNVLKDKVENGAHRIDGKEVEVKRAI 94          
BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO30149 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1M0])

HSP 1 Score: 45.8246 bits (107), Expect = 1.077e-6
Identity = 21/79 (26.58%), Postives = 46/79 (58.23%), Query Frame = 1
Query:  391 IFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPA 627
            +  + ++ +E+ + + F  YG+I N+ + +DR      GYA ++Y+  + A  A++  +G E+ G NI +D++  + P+
Sbjct:    9 VTNIHEEAQEDDIHELFSDYGEIKNLHVNLDRRTGFIKGYALVEYETFKEAQSALEALNGAEMLGQNISVDWAFIRGPS 87          
BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: tra2b (transformer 2 beta homolog [Source:NCBI gene;Acc:100049285])

HSP 1 Score: 82.8037 bits (203), Expect = 2.001e-17
Identity = 36/87 (41.38%), Postives = 57/87 (65.52%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P  C+G+FGLS  T E  L D F KYG + +V ++ D+  R S G+AF+ ++    A +A ++A+G E+DG  IR+D+S+ K+P
Sbjct:  117 NPDPNACLGVFGLSLYTTERDLKDVFSKYGPLADVSIVYDQQSRRSRGFAFVYFENTPDAKEAKEKANGMELDGRRIRVDFSITKRP 203          
BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: tra2b (transformer 2 beta homolog [Source:NCBI gene;Acc:100049285])

HSP 1 Score: 82.0333 bits (201), Expect = 4.702e-17
Identity = 36/87 (41.38%), Postives = 57/87 (65.52%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P  C+G+FGLS  T E  L D F KYG + +V ++ D+  R S G+AF+ ++    A +A ++A+G E+DG  IR+D+S+ K+P
Sbjct:  126 NPDPNACLGVFGLSLYTTERDLKDVFSKYGPLADVSIVYDQQSRRSRGFAFVYFENTPDAKEAKEKANGMELDGRRIRVDFSITKRP 212          
BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: tra2b (transformer 2 beta homolog [Source:NCBI gene;Acc:100049285])

HSP 1 Score: 82.0333 bits (201), Expect = 4.721e-17
Identity = 36/87 (41.38%), Postives = 57/87 (65.52%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKP 624
            N +P  C+G+FGLS  T E  L D F KYG + +V ++ D+  R S G+AF+ ++    A +A ++A+G E+DG  IR+D+S+ K+P
Sbjct:  112 NPDPNACLGVFGLSLYTTERDLKDVFSKYGPLADVSIVYDQQSRRSRGFAFVYFENTPDAKEAKEKANGMELDGRRIRVDFSITKRP 198          
BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: tra2a (transformer-2 protein homolog alpha [Source:NCBI gene;Acc:101157868])

HSP 1 Score: 80.8777 bits (198), Expect = 7.234e-17
Identity = 33/90 (36.67%), Postives = 58/90 (64.44%), Query Frame = 1
Query:  361 ENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPAS 630
            EN +P TC+G+FGL+  T E  L + F +YG++  + ++ D+    S G+AFI ++ +  A +A++  +G  +DG  IR+DYS+ K+P +
Sbjct:  103 ENPDPSTCLGVFGLNLSTTERDLREVFSRYGRLTGINMVHDQRTGRSRGFAFIYFERLCDAREAIEHTNGMNMDGRQIRVDYSITKRPHT 192          
BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: tra2a (transformer 2a [Source:NCBI gene;Acc:100049284])

HSP 1 Score: 78.5666 bits (192), Expect = 4.951e-16
Identity = 34/86 (39.53%), Postives = 56/86 (65.12%), Query Frame = 1
Query:  364 NAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            N +P  C+G+FGLS  T E  L + F KYG +  V ++ D+  R S G+AF+ ++  E + +A ++A+G E+DG  IR+D+S+ K+
Sbjct:  110 NPDPSCCLGVFGLSLYTTERDLREVFSKYGPLSEVNIVYDQQSRRSRGFAFVYFENSEDSKEAKEQANGMELDGRRIRVDFSITKR 195          
BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000045560.1 (SMESG000045560.1)

HSP 1 Score: 305.834 bits (782), Expect = 3.796e-102
Identity = 271/271 (100.00%), Postives = 271/271 (100.00%), Query Frame = 1
Query:   58 MSDSPSEVTNKRSLRRRDSSSPVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFNRMKNENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPASTRFFKDTASTPYNRYDSKYRNNGYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHKDSIKRKSRSKNSYG 870
            MSDSPSEVTNKRSLRRRDSSSPVLSHKNKSLSKSRSLGKRHSRSSSRTSSVKSRSHSDRGNKRRYSSPRSKRRYSRSRSYKNERRSRKSPPRYSKFNRMKNENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPASTRFFKDTASTPYNRYDSKYRNNGYRDQRRRSRSKSSSRGSYRRRRDSVTRRSRSRRSRSGSYRRHKDSIKRKSRSKNSYG
Sbjct:    1 MSDSPSEVTNKRSLRRRDSSSPVLSHKNKSLSKSRSLGKRHSRSSSRTSSVKSRSHSDRGNKRRYSSPRSKRRYSRSRSYKNERRSRKSPPRYSKFNRMKNENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPASTRFFKDTASTPYNRYDSKYRNNGYRDQRRRSRSKSSSRGSYRRRRDSVTRRSRSRRSRSGSYRRHKDSIKRKSRSKNSYG 271          
BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000052833.1 (SMESG000052833.1)

HSP 1 Score: 117.087 bits (292), Expect = 5.328e-30
Identity = 60/122 (49.18%), Postives = 80/122 (65.57%), Query Frame = 1
Query:  349 RMKNENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPASTRFFKDTASTP----YNRYDSKYRNNGY 702
            R  NEN EPC+CIG+FGLSK+T E  L + FEK+G+I  V LIMD+ + ESLGY FI+Y++++ A +A+KE +G  IDG +IR+DYS+ KK          A TP    Y    S  RNNG+
Sbjct:   64 RTNNENPEPCSCIGVFGLSKRTDERELRETFEKFGRIKTVTLIMDKYQHESLGYGFINYEDLDSATRAIKEGNGMNIDGKDIRVDYSITKK----------AHTPTPGTYKGKTSNRRNNGF 175          
BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000052829.1 (SMESG000052829.1)

HSP 1 Score: 111.694 bits (278), Expect = 4.739e-28
Identity = 47/84 (55.95%), Postives = 68/84 (80.95%), Query Frame = 1
Query:  370 EPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            EPC CIG+FGL+K+T+E+ LW+ FEK+G+I +V+LIMD+  +ESLGY FI+Y+++  A +A+KEA G  +DG  IR+DYS+ KK
Sbjct:   74 EPCKCIGVFGLNKRTEEKILWETFEKFGRIASVKLIMDKYHQESLGYGFINYEDLGSATRAVKEASGMNLDGKVIRVDYSITKK 157          
BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000052838.1 (SMESG000052838.1)

HSP 1 Score: 107.071 bits (266), Expect = 2.720e-25
Identity = 47/88 (53.41%), Postives = 64/88 (72.73%), Query Frame = 1
Query:  358 NENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            N   +P TCIGIFGLSKKT E TLW  F  +GKI +V LI+D+  +ESLG+AFI+Y+E++ A  A+KE +G  +D   +R+DYS+ KK
Sbjct:   53 NTTPDPSTCIGIFGLSKKTSERTLWKTFGNFGKIKSVSLIVDKFTKESLGFAFINYEELDSATNAIKETNGMTLDSKVVRVDYSITKK 140          
BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000063924.1 (SMESG000063924.1)

HSP 1 Score: 102.064 bits (253), Expect = 2.269e-24
Identity = 43/83 (51.81%), Postives = 64/83 (77.11%), Query Frame = 1
Query:  373 PCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 621
            P   +GIFGLS+KT E+ LW  F+KYGKI++++L+M+R   ES GY+FI+Y++I+ A++A+KE  G  +DG  IR+DYS GK+
Sbjct:  153 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKR 235          
The following BLAST results are available for this feature:
BLAST of RRM domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TRA2B6.486e-1840.45transformer 2 beta homolog [Source:HGNC Symbol;Acc... [more]
TRA2B2.476e-1741.38transformer 2 beta homolog [Source:HGNC Symbol;Acc... [more]
TRA2A7.054e-1740.70transformer 2 alpha homolog [Source:HGNC Symbol;Ac... [more]
TRA2A7.212e-1740.70transformer 2 alpha homolog [Source:HGNC Symbol;Ac... [more]
TRA2A7.212e-1740.70transformer 2 alpha homolog [Source:HGNC Symbol;Ac... [more]
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BLAST of RRM domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rsp-81.492e-1339.08SR Protein (Splicing factor) [Source:UniProtKB/Tr... [more]
rsp-81.492e-1339.08SR Protein (Splicing factor) [Source:UniProtKB/Tr... [more]
rbm-3.13.117e-734.33RNA Binding Motif protein homolog [Source:UniProt... [more]
rnp-44.442e-729.89RNA-binding protein 8A [Source:UniProtKB/TrEMBL;A... [more]
rnp-44.442e-729.89RNA-binding protein 8A [Source:UniProtKB/TrEMBL;A... [more]
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BLAST of RRM domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tra21.861e-1529.29gene:FBgn0003742 transcript:FBtr0089616[more]
tra24.208e-1529.29gene:FBgn0003742 transcript:FBtr0089615[more]
tra24.208e-1529.29gene:FBgn0003742 transcript:FBtr0089619[more]
tra26.943e-1529.29gene:FBgn0003742 transcript:FBtr0089620[more]
tra26.943e-1529.29gene:FBgn0003742 transcript:FBtr0089621[more]
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BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tra2a2.645e-1842.53transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G... [more]
tra2a2.645e-1842.53transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G... [more]
tra2a8.473e-1842.53transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G... [more]
tra2a1.176e-1742.53transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G... [more]
tra2b1.225e-1641.38transformer 2 beta homolog [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rit16.103e-1740.23Ras-like without CAAX 1 [Source:Xenbase;Acc:XB-GEN... [more]
plekhg51.344e-1641.86pleckstrin homology and RhoGEF domain containing G... [more]
cirbp4.017e-836.62cold inducible RNA binding protein [Source:NCBI ge... [more]
cirbp4.712e-836.62cold inducible RNA binding protein [Source:NCBI ge... [more]
adat15.166e-836.59adenosine deaminase, tRNA-specific 1 [Source:Xenba... [more]
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BLAST of RRM domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tra2b4.453e-1840.45transformer 2 beta [Source:MGI Symbol;Acc:MGI:1060... [more]
Tra2b1.700e-1741.38transformer 2 beta [Source:MGI Symbol;Acc:MGI:1060... [more]
Tra2a1.709e-1640.70transformer 2 alpha [Source:MGI Symbol;Acc:MGI:193... [more]
Tra2a1.756e-1640.70transformer 2 alpha [Source:MGI Symbol;Acc:MGI:193... [more]
Snrnp355.813e-1039.53small nuclear ribonucleoprotein 35 (U11/U12) [Sour... [more]
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BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P62997|TRA2B_RAT1.189e-1641.38Transformer-2 protein homolog beta OS=Rattus norve... [more]
sp|P62996|TRA2B_MOUSE1.189e-1641.38Transformer-2 protein homolog beta OS=Mus musculus... [more]
sp|P62995|TRA2B_HUMAN1.189e-1641.38Transformer-2 protein homolog beta OS=Homo sapiens... [more]
sp|Q3ZBT6|TRA2B_BOVIN1.189e-1641.38Transformer-2 protein homolog beta OS=Bos taurus O... [more]
sp|Q6PFR5|TRA2A_MOUSE1.212e-1540.70Transformer-2 protein homolog alpha OS=Mus musculu... [more]
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BLAST of RRM domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S6KMI28.160e-2151.81RRM domain-containing protein OS=Schmidtea mediter... [more]
A0A0K0G1668.726e-1851.14Transformer-2 sex-determining protein (inferred by... [more]
A0A0N5BMA38.726e-1851.14RRM domain-containing protein OS=Strongyloides pap... [more]
A0A4S2L5X91.164e-1745.56RRM domain-containing protein OS=Opisthorchis feli... [more]
A0A074ZLA81.360e-1745.56RRM domain-containing protein OS=Opisthorchis vive... [more]
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BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tra2a6.096e-1841.38transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G... [more]
tra2a8.423e-1840.45transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G... [more]
ENSAMXT00000034164.11.714e-1739.33pep primary_assembly:Astyanax_mexicanus-2.0:12:654... [more]
tra2b1.733e-1639.33transformer-2 protein homolog alpha-like [Source:N... [more]
cirbpb2.005e-842.25cold inducible RNA binding protein b [Source:ZFIN;... [more]
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BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tra2b1.377e-1538.37transformer 2 beta homolog [Source:ZFIN;Acc:ZDB-GE... [more]
tra2a2.060e-1538.37transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G... [more]
srsf2b2.290e-931.25serine and arginine rich splicing factor 2b [Sourc... [more]
ENSPMAT00000002832.19.731e-932.05pep scaffold:Pmarinus_7.0:GL476732:699988:701739:-... [more]
ncl4.183e-833.33nucleolin [Source:ZFIN;Acc:ZDB-GENE-030131-6986][more]
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BLAST of RRM domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
NSR13.133e-1136.70Nucleolar protein that binds nuclear localization ... [more]
RIE19.272e-634.18Putative RNA binding protein; localizes to stress ... [more]
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BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO448028.727e-1639.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO422981.103e-940.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO384456.427e-935.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO365228.335e-730.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO301491.077e-626.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of RRM domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tra2b2.001e-1741.38transformer 2 beta homolog [Source:NCBI gene;Acc:1... [more]
tra2b4.702e-1741.38transformer 2 beta homolog [Source:NCBI gene;Acc:1... [more]
tra2b4.721e-1741.38transformer 2 beta homolog [Source:NCBI gene;Acc:1... [more]
tra2a7.234e-1736.67transformer-2 protein homolog alpha [Source:NCBI g... [more]
tra2a4.951e-1639.53transformer 2a [Source:NCBI gene;Acc:100049284][more]
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BLAST of RRM domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000045560.13.796e-102100.00SMESG000045560.1[more]
SMESG000052833.15.328e-3049.18SMESG000052833.1[more]
SMESG000052829.14.739e-2855.95SMESG000052829.1[more]
SMESG000052838.12.720e-2553.41SMESG000052838.1[more]
SMESG000063924.12.269e-2451.81SMESG000063924.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003989 ID=SMED30003989|Name=RRM domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1268bp
GTTCAATTCATATTGTTTAAATATTATACATTAGTAAAATAATTGAAATT
TTTAAAAATGTCTGATAGTCCTTCAGAAGTTACAAATAAAAGAAGTTTGC
GTCGAAGAGATTCTTCTTCGCCTGTTTTGTCTCATAAAAATAAATCACTA
TCAAAATCCAGAAGTTTAGGAAAACGCCATTCACGTAGTTCTTCACGAAC
GTCGTCAGTCAAATCACGGTCACACTCTGATAGAGGTAATAAAAGAAGGT
ATTCATCACCTAGGTCAAAGCGCCGATATTCTAGGAGCAGGTCATATAAA
AACGAACGCCGATCAAGGAAATCGCCTCCGCGATATAGCAAATTTAATCG
AATGAAAAATGAAAATGCAGAGCCATGCACTTGTATCGGAATTTTTGGTT
TATCTAAAAAAACAAAAGAAGAAACTTTATGGGATAAATTTGAAAAGTAT
GGAAAAATTGATAATGTTCGATTGATAATGGATCGTGGTAAACGTGAATC
ACTAGGTTATGCTTTTATCGACTATAAAGAAATTGAGTTTGCTATGAAAG
CTATGAAGGAAGCTCATGGCACCGAAATTGATGGTAATAATATTCGCCTT
GATTACAGTGTTGGTAAAAAGCCGGCTAGTACTCGTTTTTTTAAAGACAC
TGCTTCTACTCCATACAATAGGTATGATTCAAAGTATCGTAACAATGGAT
ATCGCGATCAAAGGCGACGATCTCGTTCGAAGTCAAGCAGTAGAGGATCG
TATAGGAGGCGCCGTGATTCAGTTACAAGGCGATCTCGATCCAGACGTTC
ACGTAGTGGATCATATAGAAGGCATAAAGATTCGATTAAGCGAAAGTCAA
GATCGAAAAATTCTTATGGTTCTAGAAGAAGAAAGACATCTAGAAGACGA
TCAAATTCGCGACGATCTACTCATTCTTCCCGATGATCGAGTTTGCTTCA
AAATAAAATATTCAATAATTGTAATTATATTAAATAATTTGTTAATATTT
TTGATTTATTTGATATTTTTATGATACCAATGAATAATGTTAAAAAATGA
CGTTATTTGTCTTAAATGTGATTATCTAAATATTCACTCTATCAATGTTT
GTAAGAATGAGTAATATTGGCTTTTGTTCTGTTAATGGTTGAATTACAGT
TGATATGCATCAGACAGGTTCTGTTTAATTAATCGTATTTATTGAATTTT
ATTTTTGTAATTAAATGCGGGAAAATGCTGTTGTGAAATATTAATAAATT
TTAACATTTGAAAAAAAA
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protein sequence of SMED30003989-orf-1

>SMED30003989-orf-1 ID=SMED30003989-orf-1|Name=SMED30003989-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=153bp
MAPKLMVIIFALITVLVKSRLVLVFLKTLLLLHTIGMIQSIVTMDIAIKG
DDLVRSQAVEDRIGGAVIQLQGDLDPDVHVVDHIEGIKIRLSESQDRKIL
MVLEEERHLEDDQIRDDLLILPDDRVCFKIKYSIIVIILNNLLIFLIYLI
FL*
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protein sequence of SMED30003989-orf-2

>SMED30003989-orf-2 ID=SMED30003989-orf-2|Name=SMED30003989-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=293bp
MSDSPSEVTNKRSLRRRDSSSPVLSHKNKSLSKSRSLGKRHSRSSSRTSS
VKSRSHSDRGNKRRYSSPRSKRRYSRSRSYKNERRSRKSPPRYSKFNRMK
NENAEPCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLG
YAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKKPASTRFFKDTAS
TPYNRYDSKYRNNGYRDQRRRSRSKSSSRGSYRRRRDSVTRRSRSRRSRS
GSYRRHKDSIKRKSRSKNSYGSRRRKTSRRRSNSRRSTHSSR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR035979RBD_domain_sf
IPR000504RRM_dom
IPR012677Nucleotide-bd_a/b_plait_sf
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0000166nucleotide binding
GO:0003723RNA binding
Vocabulary: biological process
TermDefinition
GO:0000398mRNA splicing, via spliceosome
GO:0006397mRNA processing
GO:0008380RNA splicing
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0045335phagocytic vesicle
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000504RNA recognition motif domainSMARTSM00360rrm1_1coord: 109..182
e-value: 1.2E-18
score: 77.9
IPR000504RNA recognition motif domainPFAMPF00076RRM_1coord: 112..180
e-value: 1.7E-14
score: 53.4
IPR000504RNA recognition motif domainPROSITEPS50102RRMcoord: 108..186
score: 15.221
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 3..194
e-value: 2.3E-25
score: 91.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 205..292
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 222..292
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 32..47
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 65..83
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..99
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 9..23
NoneNo IPR availablePANTHERPTHR15481RIBONUCLEIC ACID BINDING PROTEIN S1coord: 11..285
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 47..184