transient receptor potential cation channel subfamily M member 3

Overview
Nametransient receptor potential cation channel subfamily M member 3
Smed IDSMED30003947
Length (bp)2632
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of transient receptor potential cation channel subfamily M member 3 (SMED30003947) t-SNE clustered cells

Violin plots show distribution of expression levels for transient receptor potential cation channel subfamily M member 3 (SMED30003947) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of transient receptor potential cation channel subfamily M member 3 (SMED30003947) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for transient receptor potential cation channel subfamily M member 3 (SMED30003947) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30003947

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 16

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30003947h1SMcG0022039 dd_Smed_v4_18934_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003947h1SMcG0022039 dd_Smed_v4_18934_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30003947h1SMcG0022039 dd_Smed_v4_18934_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30003947h1SMcG0022039 dd_Smed_v4_18934_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30003947h1SMcG0022039 dd_Smed_v4_18934_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003947h1SMcG0022039 dd_Smed_v4_18934_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30003947h1SMcG0022039 dd_Smed_v4_18934_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30003947h1SMcG0022039 dd_Smed_v4_10485_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30003947h1SMcG0022039 dd_Smed_v4_10485_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30003947h1SMcG0022039 Contig55242newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30003947h1SMcG0022039 Contig55242uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30003947h1SMcG0022039 dd_Smed_v6_18934_0_6dd_Smed_v6PMID:30399335
Ross et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30003947h1SMcG0022039 SMED30003947smed_20140614PMID:26457503
Tu et al., 2015
whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30003947h1SMcG0022039 SMED30003947smed_20140614PMID:26457503
Tu et al., 2015
whole organism asexual adult colorimetric in situ hybridization evidence
reproductive organSMED30003947h1SMcG0022039 Contig9876newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30003947h1SMcG0022039 Contig9876uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Human
Match: TRPM2 (transient receptor potential cation channel subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:12339])

HSP 1 Score: 77.7962 bits (190), Expect = 7.602e-14
Identity = 90/374 (24.06%), Postives = 164/374 (43.85%), Query Frame = 2
Query: 1364 IEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDK-ELPNNRGXXXXXXXXXXXXXXXRIFF--------------------SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQI-ANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELK 2419
            I +L IWA++    E+A ++W    D I  AL  +  LK++    K +    S+E++   +++YE  A  +    Y K   RA +L+ R    WG  +CLQ+++     +F S    + +    WW +  + N         +         I F                    +P   + L  +SYF F+  F YV  V  +P+           E  ++L++F L+ EE++Q+  + +   L  +   ++   WN  D+  I LF   + CR      Y    R + ++   LF LR +  F I +  G KII++K+M+ ++F FL L  ++++++G   Q+I   N +    L      + Y  ++G++ 
Sbjct:  602 IRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELS---KEEEDTDSSEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVP-------SWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLY--PGRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIP 963          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Human
Match: TRPM2 (transient receptor potential cation channel subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:12339])

HSP 1 Score: 77.411 bits (189), Expect = 9.419e-14
Identity = 90/375 (24.00%), Postives = 164/375 (43.73%), Query Frame = 2
Query: 1364 IEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNRGXXXXXXXXXXXXXXXRIFFS----------------------PTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQI-ANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELK 2419
            I +L IWA++    E+A ++W    D I  AL  +  LK++    K +    S+E++   +++YE  A  +    Y K   RA +L+ R    WG  +CLQ+++     +F S    + +    WW  +L  + G  +      +         S                      P   + L  +SYF F+  F YV  V  +P+           E  ++L++F L+ EE++Q+  + +   L  +   ++   WN  D+  I LF   + CR      Y    R + ++   LF LR +  F I +  G KII++K+M+ ++F FL L  ++++++G   Q+I   N +    L      + Y  ++G++ 
Sbjct:  622 IRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELS---KEEEDTDSSEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWG-QLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVP-------SWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLY--PGRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIP 983          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Human
Match: TRPM2 (transient receptor potential cation channel subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:12339])

HSP 1 Score: 77.411 bits (189), Expect = 1.079e-13
Identity = 90/374 (24.06%), Postives = 164/374 (43.85%), Query Frame = 2
Query: 1364 IEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDK-ELPNNRGXXXXXXXXXXXXXXXRIFF--------------------SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQI-ANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELK 2419
            I +L IWA++    E+A ++W    D I  AL  +  LK++    K +    S+E++   +++YE  A  +    Y K   RA +L+ R    WG  +CLQ+++     +F S    + +    WW +  + N         +         I F                    +P   + L  +SYF F+  F YV  V  +P+           E  ++L++F L+ EE++Q+  + +   L  +   ++   WN  D+  I LF   + CR      Y    R + ++   LF LR +  F I +  G KII++K+M+ ++F FL L  ++++++G   Q+I   N +    L      + Y  ++G++ 
Sbjct:  622 IRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELS---KEEEDTDSSEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVP-------SWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLY--PGRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIP 983          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Human
Match: TRPM2 (transient receptor potential cation channel subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:12339])

HSP 1 Score: 77.411 bits (189), Expect = 1.079e-13
Identity = 90/374 (24.06%), Postives = 164/374 (43.85%), Query Frame = 2
Query: 1364 IEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDK-ELPNNRGXXXXXXXXXXXXXXXRIFF--------------------SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQI-ANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELK 2419
            I +L IWA++    E+A ++W    D I  AL  +  LK++    K +    S+E++   +++YE  A  +    Y K   RA +L+ R    WG  +CLQ+++     +F S    + +    WW +  + N         +         I F                    +P   + L  +SYF F+  F YV  V  +P+           E  ++L++F L+ EE++Q+  + +   L  +   ++   WN  D+  I LF   + CR      Y    R + ++   LF LR +  F I +  G KII++K+M+ ++F FL L  ++++++G   Q+I   N +    L      + Y  ++G++ 
Sbjct:  622 IRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELS---KEEEDTDSSEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVP-------SWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLY--PGRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIP 983          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Human
Match: TRPM5 (transient receptor potential cation channel subfamily M member 5 [Source:HGNC Symbol;Acc:HGNC:14323])

HSP 1 Score: 69.707 bits (169), Expect = 2.450e-11
Identity = 55/204 (26.96%), Postives = 106/204 (51.96%), Query Frame = 2
Query: 1826 SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQ-IANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFE 2434
            +P + +    + YF F+  F YV  V  +P      +   G E+ ++ +VF L++EEI+Q     E   L  +F  +    WN  D++ I LF + + CR  +    F   R + A+   +F LR +  F I ++ G KII++++M+ ++F FL    ++++AYG   Q++ +P+      +   +   PY Q++G++ +D+ +
Sbjct:  724 APVTVFLGNVVMYFAFLFLFTYVLLVDFRPPP----QGPSGPEVTLYFWVFTLVLEEIRQGFFTDEDTHLVKKFTLYVGDNWNKCDMVAIFLFIVGVTCR--MLPSAFEAGRTVLAMDFMVFTLRLIHIFAIHKQLGPKIIVVERMMKDVFFFLFFLSVWLVAYGVTTQALLHPHDGRLEWIFRRVLYRPYLQIFGQIPLDEID 921          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971])

HSP 1 Score: 72.4034 bits (176), Expect = 1.341e-12
Identity = 55/207 (26.57%), Postives = 95/207 (45.89%), Query Frame = 2
Query: 1820 FFS-PTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFES 2437
            F+S P S +W + IS+ +FI  F Y   V   P   V        E  +  YV    +E++++I   + K  Y + + +    WN   IL I  + +    R      Y    R + A    L+ ++ L +  +  K G  + M  KM+  +   + +  + +L++G   QSI  P+  W   L+ +IFL PYF +YGE+  D+ ++
Sbjct: 1201 FYSAPISTFWSWTISFILFITFFTYTLLVKTPPRPTV-------IEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCFGSVAY---GRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDT 1397          

HSP 2 Score: 53.9138 bits (128), Expect = 5.447e-7
Identity = 29/131 (22.14%), Postives = 67/131 (51.15%), Query Frame = 2
Query: 1328 GTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCS-AEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACE 1717
            G+    + +Y Y  EL IWA+L+   ++A  +W+   + +  AL      K +  +     L+    E++ K ++++ +L+ ++++  Y     + ++L+   L+ W N++CL ++V  + K F +   C+
Sbjct:  841 GSQTEPDFRYPY-SELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQ 970          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971])

HSP 1 Score: 72.4034 bits (176), Expect = 1.346e-12
Identity = 55/207 (26.57%), Postives = 95/207 (45.89%), Query Frame = 2
Query: 1820 FFS-PTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFES 2437
            F+S P S +W + IS+ +FI  F Y   V   P   V        E  +  YV    +E++++I   + K  Y + + +    WN   IL I  + +    R      Y    R + A    L+ ++ L +  +  K G  + M  KM+  +   + +  + +L++G   QSI  P+  W   L+ +IFL PYF +YGE+  D+ ++
Sbjct: 1241 FYSAPISTFWSWTISFILFITFFTYTLLVKTPPRPTV-------IEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCFGSVAY---GRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDT 1437          

HSP 2 Score: 54.299 bits (129), Expect = 5.369e-7
Identity = 29/131 (22.14%), Postives = 67/131 (51.15%), Query Frame = 2
Query: 1328 GTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCS-AEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACE 1717
            G+    + +Y Y  EL IWA+L+   ++A  +W+   + +  AL      K +  +     L+    E++ K ++++ +L+ ++++  Y     + ++L+   L+ W N++CL ++V  + K F +   C+
Sbjct:  881 GSQTEPDFRYPY-SELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQ 1010          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971])

HSP 1 Score: 72.4034 bits (176), Expect = 1.473e-12
Identity = 55/207 (26.57%), Postives = 95/207 (45.89%), Query Frame = 2
Query: 1820 FFS-PTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFES 2437
            F+S P S +W + IS+ +FI  F Y   V   P   V        E  +  YV    +E++++I   + K  Y + + +    WN   IL I  + +    R      Y    R + A    L+ ++ L +  +  K G  + M  KM+  +   + +  + +L++G   QSI  P+  W   L+ +IFL PYF +YGE+  D+ ++
Sbjct: 1302 FYSAPISTFWSWTISFILFITFFTYTLLVKTPPRPTV-------IEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCFGSVAY---GRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDT 1498          

HSP 2 Score: 53.9138 bits (128), Expect = 5.621e-7
Identity = 29/131 (22.14%), Postives = 67/131 (51.15%), Query Frame = 2
Query: 1328 GTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCS-AEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACE 1717
            G+    + +Y Y  EL IWA+L+   ++A  +W+   + +  AL      K +  +     L+    E++ K ++++ +L+ ++++  Y     + ++L+   L+ W N++CL ++V  + K F +   C+
Sbjct:  942 GSQTEPDFRYPY-SELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQ 1071          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971])

HSP 1 Score: 68.9366 bits (167), Expect = 1.337e-11
Identity = 54/208 (25.96%), Postives = 96/208 (46.15%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXS--MICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFES 2437
            + +P S +W + IS+ +FI  F Y   V   P   V        E  +  YV    +E++++I   + K  Y + + +    WN   IL I  + +   M C  S+        R + A    L+ ++ L +  +  K G  + M  KM+  +   + +  + +L++G   QSI  P+  W   L+ +IFL PYF +YGE+  D+ ++
Sbjct:  897 YSAPISTFWSWTISFILFITFFTYTLLVKTPPRPTV-------IEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCFGSV-----AYGRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDT 1092          

HSP 2 Score: 50.8322 bits (120), Expect = 5.706e-6
Identity = 29/131 (22.14%), Postives = 67/131 (51.15%), Query Frame = 2
Query: 1328 GTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCS-AEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACE 1717
            G+    + +Y Y  EL IWA+L+   ++A  +W+   + +  AL      K +  +     L+    E++ K ++++ +L+ ++++  Y     + ++L+   L+ W N++CL ++V  + K F +   C+
Sbjct:  536 GSQTEPDFRYPY-SELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQ 665          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Celegans
Match: gtl-2 (Gon-Two Like (TRP subfamily) [Source:UniProtKB/TrEMBL;Acc:Q20766])

HSP 1 Score: 55.8398 bits (133), Expect = 1.469e-7
Identity = 54/206 (26.21%), Postives = 91/206 (44.17%), Query Frame = 2
Query: 1814 RIFFS-PTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSR---FQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRK-WDISLLVDIFLYPYFQMYGEL 2416
            R F+S P +K+W + I++ IF+        +LL   SL   K E       F+Y   L VE I+++   EG  +  +   F   W   W    +L   + +   +     H       R L + +  LF ++  ++  +    G  I M  KM+  +     L  + ++A+G   Q++  PN K W   L+ +IF  PYF +YGE+
Sbjct:  890 RAFYSSPITKFWSWCIAFLIFLTT---QTCILLLETSLKPSKYEW----ITFIYTVTLSVEHIRKLMTSEGSRINEKVKVFYAKWYNIWTSAALLFFLVGYGFRLVPMYRHS----WGRVLLSFSNVLFYMKIFEYLSVHPLLGPYIQMAAKMVWSMCYICVLLLVPLMAFGVNRQALTEPNVKDWHWLLVRNIFYKPYFMLYGEV 1084          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339077)

HSP 1 Score: 60.077 bits (144), Expect = 9.742e-9
Identity = 51/199 (25.63%), Postives = 98/199 (49.25%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGEL 2416
            + +P +K+W   I+Y  F++ F +  +VL+K   + + +     E +   Y+  L  E++++I + E   +  +F       WN  D   I LF + +  RF   E+   I R +  V    + LR L    + +  G  + M+ KM+  +  F+ L  + ++++G   Q+I  PN++   SL+ ++   PYF +YGE+
Sbjct:  921 YTAPITKFWADSIAYMFFLIMFSF--TVLVKMEQMPRWQ-----EWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF--RENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEV 1110          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339074)

HSP 1 Score: 59.6918 bits (143), Expect = 1.197e-8
Identity = 51/199 (25.63%), Postives = 98/199 (49.25%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGEL 2416
            + +P +K+W   I+Y  F++ F +  +VL+K   + + +     E +   Y+  L  E++++I + E   +  +F       WN  D   I LF + +  RF   E+   I R +  V    + LR L    + +  G  + M+ KM+  +  F+ L  + ++++G   Q+I  PN++   SL+ ++   PYF +YGE+
Sbjct:  837 YTAPITKFWADSIAYMFFLIMFSF--TVLVKMEQMPRWQ-----EWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF--RENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEV 1026          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339080)

HSP 1 Score: 59.6918 bits (143), Expect = 1.199e-8
Identity = 51/199 (25.63%), Postives = 98/199 (49.25%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGEL 2416
            + +P +K+W   I+Y  F++ F +  +VL+K   + + +     E +   Y+  L  E++++I + E   +  +F       WN  D   I LF + +  RF   E+   I R +  V    + LR L    + +  G  + M+ KM+  +  F+ L  + ++++G   Q+I  PN++   SL+ ++   PYF +YGE+
Sbjct:  866 YTAPITKFWADSIAYMFFLIMFSF--TVLVKMEQMPRWQ-----EWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF--RENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEV 1055          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339076)

HSP 1 Score: 59.6918 bits (143), Expect = 1.226e-8
Identity = 51/199 (25.63%), Postives = 98/199 (49.25%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGEL 2416
            + +P +K+W   I+Y  F++ F +  +VL+K   + + +     E +   Y+  L  E++++I + E   +  +F       WN  D   I LF + +  RF   E+   I R +  V    + LR L    + +  G  + M+ KM+  +  F+ L  + ++++G   Q+I  PN++   SL+ ++   PYF +YGE+
Sbjct:  819 YTAPITKFWADSIAYMFFLIMFSF--TVLVKMEQMPRWQ-----EWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF--RENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEV 1008          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339079)

HSP 1 Score: 59.6918 bits (143), Expect = 1.248e-8
Identity = 51/199 (25.63%), Postives = 98/199 (49.25%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGEL 2416
            + +P +K+W   I+Y  F++ F +  +VL+K   + + +     E +   Y+  L  E++++I + E   +  +F       WN  D   I LF + +  RF   E+   I R +  V    + LR L    + +  G  + M+ KM+  +  F+ L  + ++++G   Q+I  PN++   SL+ ++   PYF +YGE+
Sbjct:  826 YTAPITKFWADSIAYMFFLIMFSF--TVLVKMEQMPRWQ-----EWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF--RENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEV 1015          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Zebrafish
Match: trpm6 (transient receptor potential cation channel, subfamily M, member 6 [Source:ZFIN;Acc:ZDB-GENE-111212-1])

HSP 1 Score: 78.9518 bits (193), Expect = 2.241e-14
Identity = 87/410 (21.22%), Postives = 172/410 (41.95%), Query Frame = 2
Query: 1370 ELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNL-DCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGN-----------------KSCLQISVNE--------------------------DLKEFCSKSACEHYARLA-----WWD----------KELPNN--RGXXXXXXXXXXXXXXXRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGEL 2416
            +LF+WA+L    E+A +LW+     +  A+      + +  + K  N+ D  AE++ K S ++  LA  +++ A+ ++   A++L+   +  W N                  +C Q+ + +                           L EF S++   H  +L       WD          K +P +  RG                 + +P  K+W + +++  F++ F Y   V L     ++       E  V  Y+  + VE+ +++   E +    + +  +   WNI D L I LF + +  R+  H++  + S  + ++    + +R L  F + Q  G  + MI KM+  +F  + +  L ++++GT  +SI +PN     +LL D+   PY+ ++GE+
Sbjct:  599 DLFVWAVLKHRQEMALLLWQHGEQAMARAVVACKLYRTLAMEAKESNMGDTMAEELKKNSLEFGQLAVDVLDQAFRENERMAMKLLTWEMKDWSNFTCLQMAVSSGLRPFVAHNCTQMLLTDLWMGRLNLSKNSWFKIIGSILMPVAIQLLEFKSQAEMSHVPQLQEALQFGWDTVPSEQEGAEKAVPGDEERGSSCLYPWTRKVYD---FYTAPVVKFWFHTMAFLGFLMMFAYTCLVRLNETPNIQ-------ECLVMTYILAMAVEKAREVLVLEPRKFTKKLKVWFSEYWNINDFLGILLFLVGVSLRW--HQETRLASHIVYSLDFVFWSVRLLDLFAVNQHAGPYLTMITKMMSNMFYIVIIMALVLVSFGTSRKSILSPNEDPSWTLLRDVVFQPYWMIFGEV 996          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736])

HSP 1 Score: 68.1662 bits (165), Expect = 4.134e-11
Identity = 56/210 (26.67%), Postives = 112/210 (53.33%), Query Frame = 2
Query: 1814 RIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQ-IANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLY-PYFQMYGELKIDKFES 2437
            R + +P + +    I YF F++ F YV  +  +P           AEI ++ +VF L++EEI+Q     E  ++  + + +    WN  D++ I LF + + CR ++    +   R + A+   +F LR +  F I ++ G KII++++M+ ++F FL    ++++AYG   Q++ +PN    I  +    LY PY  ++G++ +++ ++
Sbjct:  760 RFWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRPPPPYGPS---AAEIILYFWVFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSCRMAM--STYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDP-RIDWVFRRALYRPYLHIFGQIPLEEIDA 963          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736])

HSP 1 Score: 68.1662 bits (165), Expect = 4.255e-11
Identity = 56/210 (26.67%), Postives = 112/210 (53.33%), Query Frame = 2
Query: 1814 RIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQ-IANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLY-PYFQMYGELKIDKFES 2437
            R + +P + +    I YF F++ F YV  +  +P           AEI ++ +VF L++EEI+Q     E  ++  + + +    WN  D++ I LF + + CR ++    +   R + A+   +F LR +  F I ++ G KII++++M+ ++F FL    ++++AYG   Q++ +PN    I  +    LY PY  ++G++ +++ ++
Sbjct:  706 RFWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRPPPPYGPS---AAEIILYFWVFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSCRMAM--STYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDP-RIDWVFRRALYRPYLHIFGQIPLEEIDA 909          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736])

HSP 1 Score: 68.1662 bits (165), Expect = 4.560e-11
Identity = 56/210 (26.67%), Postives = 112/210 (53.33%), Query Frame = 2
Query: 1814 RIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQ-IANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLY-PYFQMYGELKIDKFES 2437
            R + +P + +    I YF F++ F YV  +  +P           AEI ++ +VF L++EEI+Q     E  ++  + + +    WN  D++ I LF + + CR ++    +   R + A+   +F LR +  F I ++ G KII++++M+ ++F FL    ++++AYG   Q++ +PN    I  +    LY PY  ++G++ +++ ++
Sbjct:  711 RFWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRPPPPYGPS---AAEIILYFWVFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSCRMAM--STYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDP-RIDWVFRRALYRPYLHIFGQIPLEEIDA 914          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Zebrafish
Match: trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:ZFIN;Acc:ZDB-GENE-060531-95])

HSP 1 Score: 64.3142 bits (155), Expect = 6.965e-10
Identity = 57/220 (25.91%), Postives = 111/220 (50.45%), Query Frame = 2
Query: 1826 SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKL-ELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVIS--RCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFESEFYATIHKELSLI 2476
            +P  K+W + ++Y  +++ F Y        I LVK+ L     E  V  Y+F   +E++++I   E   L  + +   +  WNI D++ I +F + M+ R    +D  ++S  R +  V +  + +R L  F + +  G  ++MI KM++++  F+ +  + ++++G   Q+I NPN      L  +IF  PY+ +YGE+  D+ +      I  E  ++
Sbjct:  728 APIVKFWFHTLAYVGYLMLFNY--------IVLVKMDLWPSPQEWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQEYWNITDLMAILIFSIGMVLRL---QDPPLMSYGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPNEDPSWMLARNIFFMPYWMIYGEVFADQIDPPCGQNITTEEGVV 936          

HSP 2 Score: 50.8322 bits (120), Expect = 9.580e-6
Identity = 27/128 (21.09%), Postives = 65/128 (50.78%), Query Frame = 2
Query: 1367 EELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDY-KNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDK 1747
             EL +WA+L    ++A   W+   + +  AL      K + ++  +N  +D  ++++ + S+++  LA ++++ +Y +    A++L+   L  W N +CLQ++V    ++F + +  +      W  +
Sbjct:  485 HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNQNSREFGQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGR 612          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Xenopus
Match: shc2 (SHC (Src homology 2 domain containing) transforming protein 2 [Source:Xenbase;Acc:XB-GENE-6073771])

HSP 1 Score: 93.5893 bits (231), Expect = 8.162e-19
Identity = 89/396 (22.47%), Postives = 177/396 (44.70%), Query Frame = 2
Query: 1370 ELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKE---SKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNN---------------------------RGXXXXXXXXXXXXXX-----XRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFESEFYAT 2452
            +LFIWA+L    E+A   W+  S+ + +AL     LK++        ++  AE+       + K+E LA  +    Y  S  RA +L+ R    WG  +CLQ++   D + F ++   +      WW +   N                             G  + + I+  +        K+ + +P + ++   + YF F+  F YV   LL    +        +E  ++ ++F ++ EEI+Q        +  + +++ +  WN  DI+ + LF + +ICR  +  + F   R +      +F LR +  F + ++ G KII+++KM+ ++F FL    ++++AYG   + + +P       +   +F  PY Q++G++  ++F++   A+
Sbjct:  547 DLFIWAILQNRDEMATYFWEMGSEAVTSALAAMKILKEL------SRMESEAEESLAMRDLAAKFEQLAIGVFNECYRNSENRAFKLLVRRSVIWGGATCLQLAYEADARNFFAQDGVQSMLTENWWGQMAQNTPVWAMVLTFFCPPLIYTDLITFNSVEQNGAPEAEIIKEKQRPRWMQRWKQFWSAPVTAFFGNVVMYFAFLFLFSYV---LLLEFKMPPPDGPANSEFILYFWIFTMVCEEIRQSFFVGTMPVAQKVKQYLQDSWNHVDIIALCLFIIGLICR--MFNESFEAGRTILCFDFMVFTLRLIHIFAVNKQLGPKIIIVRKMMKDVFFFLFFLGVWLIAYGVTTEGLLHPTDMRLSWIFRRVFYRPYLQIFGQIPQEEFDASKIAS 931          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Xenopus
Match: shc2 (SHC (Src homology 2 domain containing) transforming protein 2 [Source:Xenbase;Acc:XB-GENE-6073771])

HSP 1 Score: 87.0409 bits (214), Expect = 8.787e-17
Identity = 88/407 (21.62%), Postives = 176/407 (43.24%), Query Frame = 2
Query: 1370 ELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKE---SKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKEL--------------------------PNNRGXXXXXXXXXXXXXXX------------RIFFSPTSKYWLYWISYF----IFIVQFIYVNS-VLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFESEFYAT 2452
            +LFIWA+L    E+A   W+  S+ + +AL     LK++        ++  AE+       + K+E LA  +    Y  S  RA +L+ R    WG  +CLQ++   D + F ++   +      WW +                            PNN       +I+ +                 R+      ++W   ++ F    +    F+++ S VLL    +        +E  ++ ++F ++ EEI+Q        +  + +++ +  WN  DI+ + LF + +ICR  +  + F   R +      +F LR +  F + ++ G KII+++KM+ ++F FL    ++++AYG   + + +P       +   +F  PY Q++G++  ++F++   A+
Sbjct:  547 DLFIWAILQNRDEMATYFWEMGSEAVTSALAAMKILKELSR------MESEAEESLAMRDLAAKFEQLAIGVFNECYRNSENRAFKLLVRRSVIWGGATCLQLAYEADARNFFAQDGVQSMLTENWWGQMAQNTPVWAMVLTFFCPPLIYTDLITFKPNNYMISSHLSIDPTPHTVTINSNLLGREGCCRLLPERWKQFWSAPVTAFFGNVVMYFAFLFLFSYVLLLEFKMPPPDGPANSEFILYFWIFTMVCEEIRQSFFVGTMPVAQKVKQYLQDSWNHVDIIALCLFIIGLICR--MFNESFEAGRTILCFDFMVFTLRLIHIFAVNKQLGPKIIIVRKMMKDVFFFLFFLGVWLIAYGVTTEGLLHPTDMRLSWIFRRVFYRPYLQIFGQIPQEEFDASKIAS 945          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Xenopus
Match: ccdc125 (coiled-coil domain containing 125 [Source:Xenbase;Acc:XB-GENE-940158])

HSP 1 Score: 86.6557 bits (213), Expect = 1.145e-16
Identity = 185/816 (22.67%), Postives = 326/816 (39.95%), Query Frame = 2
Query:  194 WEFAPPKVVISIHGENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENR-QDNILDKTILLGIKRHVFEENCELDIN--DIYNGYLLY-----QTETNSYYLENIQTKF-------------ESFLKKT----------------ENINTVHIIYDGDFDIFKPVFTTLHDKIPVVLXXXXXXXXXXXXXXXLSEYNDAELNDILRTHSNSKELKTISNEIFEFKNSIILYDIKDEK---INLNRKILEA--LISNTKNTQASDEGFCRRLGN------SSKMQES--------IIYEWECFELSCIFDENSLNENSYLEKTITNDDKNKIEVMLFTVLKNNKAKALEWLMKIINTTDDYVDESFLTRLYHDSVTGNVSCVKELR-KRYDNLSG------LKSQTNSFCCKRKQQSAGIPENESFVGTSEANNKKYIY-------IEELFIWALLSGYTEVAFVLW---KFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNRGXXXXXXXXXXXXXXXRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIAN--KEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRF-SIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPN-RKWDISLLVDIFLYPYFQMYG 2410
            W+   P ++IS+ G  +  +     ++  + LI I +    WI T G  NG+ + + E V +N    +   K   +GI       N +  I   D    Y+ +     + E   YYL+N  T F             E+ L+ +                  I  V  ++ G  +  K +   +  KIP V++E S             +  D  +  ++ T   S     I  ++  F    +    +DE    I   ++I+E+  L++  K  +A DE     +        S++ Q+         ++ EW   EL+     N L  N +  KT   +D       +FT L  ++ + +  L++     D ++    L +L+ +  + +     E+  K Y+ L        L++  N +            E   F  T+    +K I+        + LFIWA+L    E++ V+W   K C+     A K   +L KV  D K      +A++  + + +YE  A  +    Y      A  L+      WG  +CL ++V  + ++F ++   +++    W+  +                  K+   F SP   +    I Y  F+  F YV  +  +PI         G EI V+L VF LL  EI+Q+    +  +  YSR       CWNI D + I  F + ++ R  + +     + R +  +   +F LR +Q F I Q  G KIIM+++M +++F FL LF ++I+A+G   Q I   N  +W+  +   +   PY  M+G
Sbjct:  100 WQLKTPNLIISVTGGARNFSLKPRIRKIIRRLIYIAQSKGAWIFTGGTHNGLTKYIGEVVRDNTISQSSEGKVAAIGIAAWGMISNRDSLIRSPDDEGKYIAHYVMDEKKEDGLYYLDNNHTHFILVDNGSYKHPTIEAELRASLEGCISELTAPDSDYSGKIPIVCFVHSGGKETLKAINRAIKSKIPCVVVEGS------------GQIADV-IASLVETEGTSVPSTIIKEKMLHFLKYTVSRLTEDELEAWIQWIKEIMESPNLLTVIKIDEAGDETVSDAISAALYKAYSTREQDKGNWNAQLKLLLEWNQLELA----NNELFANGHHWKTADLEDA------MFTALVKDRPEFVRLLLENGLDLDKFLSSEVLRQLFSEHFSTHAFKSLEMADKSYNPLLTFVWRMILRNFRNGY------------EKLVFFRTNRIGTEKNIFSLIKRHPTQVLFIWAILQNKRELSTVIWEQTKACTLAALGASKLLKHLAKVNKDIK------TAQESEEMAHEYETRAVDLFTECYSNDKKLAGMLLVHSCEAWGKSNCLDMAVAANDQQFIAQPGVQNFLSKQWYGIDW------------HYRLWKYCDFFTSPFVVFSWTVIFYIGFLFLFAYVLLMDFQPIPT-------GLEIVVYLLVFILLCIEIRQVLEYVEMNRAEYSR------DCWNIMDCMAILYFIVGVLFRLQNSNLSALYVGRVILCLDYIIFTLRLIQIFTISQNLGPKIIMLQRMFVDVFFFLFLFAVWIVAFGVANQGILRLNEHRWEW-IFRSVIYQPYLAMFG 848          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Xenopus
Match: ccdc125 (coiled-coil domain containing 125 [Source:Xenbase;Acc:XB-GENE-940158])

HSP 1 Score: 78.9518 bits (193), Expect = 2.444e-14
Identity = 97/353 (27.48%), Postives = 160/353 (45.33%), Query Frame = 2
Query: 1373 LFIWALLSGYTEVAFVLW---KFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNRGXXXXXXXXXXXXXXXRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIAN--KEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRF-SIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPN-RKWDISLLVDIFLYPYFQMYG 2410
            LFIWA+L    E++ V+W   K C+     A K   +L KV  D K      +A++  + + +YE  A  +    Y      A  L+      WG  +CL ++V  + ++F ++   +++    W+  +                  K+   F SP   +    I Y  F+  F YV  +  +PI         G EI V+L VF LL  EI+Q+    +  +  YSR       CWNI D + I  F + ++ R  + +     + R +  +   +F LR +Q F I Q  G KIIM+++M +++F FL LF ++I+A+G   Q I   N  +W+  +   +   PY  M+G
Sbjct:  522 LFIWAILQNKRELSTVIWEQTKACTLAALGASKLLKHLAKVNKDIK------TAQESEEMAHEYETRAVDLFTECYSNDKKLAGMLLVHSCEAWGKSNCLDMAVAANDQQFIAQPGVQNFLSKQWYGIDW------------HYRLWKYCDFFTSPFVVFSWTVIFYIGFLFLFAYVLLMDFQPIPT-------GLEIVVYLLVFILLCIEIRQVLEYVEMNRAEYSR------DCWNIMDCMAILYFIVGVLFRLQNSNLSALYVGRVILCLDYIIFTLRLIQIFTISQNLGPKIIMLQRMFVDVFFFLFLFAVWIVAFGVANQGILRLNEHRWEW-IFRSVIYQPYLAMFG 842          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Xenopus
Match: ccdc125 (coiled-coil domain containing 125 [Source:Xenbase;Acc:XB-GENE-940158])

HSP 1 Score: 72.7886 bits (177), Expect = 2.360e-12
Identity = 100/371 (26.95%), Postives = 166/371 (44.74%), Query Frame = 2
Query: 1373 LFIWALLSGYTEVAFVLW---KFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNR------GXXXXXXXXXXXXXXXRIFFSPTSKYWLY------------W--ISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRF-SIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPN-RKWDISLLVDIFLYPYFQMYG 2410
            LFIWA+L    E++ V+W   K C+     A K   +L KV  D K      +A++  + + +YE  A  +    Y      A  L+      WG  +CL ++V  + ++F ++   +++    W+     + +             I      F++I     S+ W Y            W  I Y  F+  F YV  +  +PI         G EI V+L VF LL  EI+Q+       + SR  ++ R CWNI D + I  F + ++ R  + +     + R +  +   +F LR +Q F I Q  G KIIM+++M +++F FL LF ++I+A+G   Q I   N  +W+  +   +   PY  M+G
Sbjct:  552 LFIWAILQNKRELSTVIWEQTKACTLAALGASKLLKHLAKVNKDIK------TAQESEEMAHEYETRAVDLFTECYSNDKKLAGMLLVHSCEAWGKSNCLDMAVAANDQQFIAQPGVQNFLSKQWYGAISRDTKTWKILLSLFIFPLISCGFITFRKISNRKRSRLWKYCDFFTSPFVVFSWTVIFYIGFLFLFAYVLLMDFQPIPT-------GLEIVVYLLVFILLCIEIRQM-------IISR-AEYSRDCWNIMDCMAILYFIVGVLFRLQNSNLSALYVGRVILCLDYIIFTLRLIQIFTISQNLGPKIIMLQRMFVDVFFFLFLFAVWIVAFGVANQGILRLNEHRWEW-IFRSVIYQPYLAMFG 900          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Mouse
Match: Trpm2 (transient receptor potential cation channel, subfamily M, member 2 [Source:MGI Symbol;Acc:MGI:1351901])

HSP 1 Score: 77.411 bits (189), Expect = 6.983e-14
Identity = 86/373 (23.06%), Postives = 167/373 (44.77%), Query Frame = 2
Query: 1364 IEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNR-------------------GXXXXXXXXXXXXXXXRIFF-SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQI-ANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELK 2419
            + +L IWA++  + E+A ++W    D    AL  +  LK++    K +    S+E++   + ++E  A  +    Y K   RA +L+ R    WG  +CLQ+++     +F S    + +    WW +   +N                      ++++     +    R FF +P   + +  +SYF F+  F YV  V  +P            E  ++L++F L+ EE +Q+  + +G  L      ++   WN  D+  I LF + + CR      Y    R + ++   +F LR +  F I +  G KII++K+M+ ++F FL L  ++++++G   Q+I   N      +   +  + Y  ++G++ 
Sbjct:  620 VRDLLIWAVIQNHRELAGIIWAQSQDCTAAALACSKILKELS---KEEEDTDSSEEMLALADEFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLFTGFISFREKRLQALCRPARVRAFFNAPVVIFHMNILSYFAFLCLFAYVLMVDFQPSP-------SWCEYLIYLWLFSLVCEETRQLFYDPDGCGLMKMASLYFSDFWNKLDVGAILLFIVGLTCRLIPATLY--PGRIILSLDFIMFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNESRVDWIFRGVVYHSYLTIFGQIP 980          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101])

HSP 1 Score: 75.0998 bits (183), Expect = 3.459e-13
Identity = 129/611 (21.11%), Postives = 237/611 (38.79%), Query Frame = 2
Query:  101 GICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHG--ENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCE---------------------LDINDIYNGYLLYQTETNSYYLENIQTKFESFLKKT---ENINT--------VHIIYDGDFDIFKPVFTTLHDKIPVVLXXXXXXXXXXXXXXXLSEYND--AELNDILR-------------THSNSKELKTISNEIFEFKNSIILYDIKDE-KINLNRKILEALISNTKNTQASDEGFCRRLGNSSKMQESIIY----EWECFEL-SCIFDENSLNENSYLEKTITNDDKNKIEVMLFTV--LKNNKAKALEWLMKIINTTDDYVDESFLTRLYHDSVTGNVSCVKELRKR----YDNLSGLKSQTNSFCCKRKQQSAGIPENESFVGTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDY-KNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDK 1747
            G  NK  Y  V  D + +    L   ++ K W+   PK++IS+HG  +N +L   K  + F + LI     T  WI T G   GV   V +A++++   +   K   +GI      EN E                       +N +++ ++L    T   Y    + K    L+K    + INT        V +I +G  ++   V   L D  PV ++       +   +    +Y++    +N+ LR             T + ++ L  I  E  + K  I ++ +  E   +++  IL AL+    N  A D+       N   +  S I+    +W    L   + D   L+   +++  I N        +   V  +K  +     W+    N   DY        L  + + G        RKR    Y NL G K         RK       E +  +   E N+  + +  EL +WA+L    ++A   W+   + +  AL      K + ++  +N  +D  ++++   S+ +  LA ++++ +Y +    A++L+   L  W N +CLQ++V    ++F + +  +      W  +
Sbjct:  148 GHSNKAMYVRVSFDTKPD----LLLHLMTKEWQLELPKLLISVHGGLQNFELQP-KLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKS-RGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA-NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPF-HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGR 748          

HSP 2 Score: 65.0846 bits (157), Expect = 4.653e-10
Identity = 54/205 (26.34%), Postives = 105/205 (51.22%), Query Frame = 2
Query: 1826 SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKL-KLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFES 2437
            +P  K+W Y ++Y  +++ F Y        I LVK+ +     E  V  Y+F L +E++++I   E   L  + +   +  WN+ D++ I LF + MI R    + +    R +  V +  + +R L  F + +  G  ++MI KM++++  F+ +  + ++++G   Q+I  PN +    L  +IF  PY+ +YGE+  D+ + 
Sbjct:  852 APIVKFWFYTLAYIGYLMLFNY--------IVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQ-DQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDP 1047          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Mouse
Match: Trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:MGI Symbol;Acc:MGI:1861718])

HSP 1 Score: 71.633 bits (174), Expect = 3.843e-12
Identity = 58/216 (26.85%), Postives = 111/216 (51.39%), Query Frame = 2
Query: 1826 SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQ-IANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKF-ESEFYATIHKEL 2467
            +P + +    + YF F+  F YV  V  +P      +   G+E+ ++ +VF L++EEI+Q     E   L  +F  +    WN  D++ I LF + + CR       F   R + A+   +F LR +  F I ++ G KII++++M+ ++F FL    ++++AYG   Q++ +P+      +   +   PY Q++G++ +D+  E+    ++H  L
Sbjct:  729 APVTVFLGNVVMYFAFLFLFTYVLLVDFRPPP----QGPSGSEVTLYFWVFTLVLEEIRQGFFTDEDTHLVKKFTLYVEDNWNKCDMVAIFLFIVGVTCRMV--PSVFEAGRTVLAIDFMVFTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLVAYGVTTQALLHPHDGRLEWIFRRVLYRPYLQIFGQIPLDEIDEARVNCSLHPLL 938          

HSP 2 Score: 52.373 bits (124), Expect = 3.170e-6
Identity = 32/124 (25.81%), Postives = 54/124 (43.55%), Query Frame = 2
Query: 1370 ELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWW 1741
            +LF+WA+L    E+A   W    + +  AL     +K++ +  K    +    +  +E+K YE LA  +    Y  S  RA  L+ R    W   +CL ++   D K F +    + +    WW
Sbjct:  519 DLFLWAVLQNRYEMATYFWAMGREGVAAALAACKIIKEMSHLEK----EAEVARTMREAK-YEQLALDLFSECYGNSEDRAFALLVRRNHSWSRTTCLHLATEADAKAFFAHDGVQAFLTKIWW 637          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Mouse
Match: Trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:MGI Symbol;Acc:MGI:1861718])

HSP 1 Score: 71.633 bits (174), Expect = 3.923e-12
Identity = 58/216 (26.85%), Postives = 111/216 (51.39%), Query Frame = 2
Query: 1826 SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQ-IANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKF-ESEFYATIHKEL 2467
            +P + +    + YF F+  F YV  V  +P      +   G+E+ ++ +VF L++EEI+Q     E   L  +F  +    WN  D++ I LF + + CR       F   R + A+   +F LR +  F I ++ G KII++++M+ ++F FL    ++++AYG   Q++ +P+      +   +   PY Q++G++ +D+  E+    ++H  L
Sbjct:  729 APVTVFLGNVVMYFAFLFLFTYVLLVDFRPPP----QGPSGSEVTLYFWVFTLVLEEIRQGFFTDEDTHLVKKFTLYVEDNWNKCDMVAIFLFIVGVTCRMV--PSVFEAGRTVLAIDFMVFTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLVAYGVTTQALLHPHDGRLEWIFRRVLYRPYLQIFGQIPLDEIDEARVNCSLHPLL 938          

HSP 2 Score: 52.373 bits (124), Expect = 3.038e-6
Identity = 32/124 (25.81%), Postives = 54/124 (43.55%), Query Frame = 2
Query: 1370 ELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWW 1741
            +LF+WA+L    E+A   W    + +  AL     +K++ +  K    +    +  +E+K YE LA  +    Y  S  RA  L+ R    W   +CL ++   D K F +    + +    WW
Sbjct:  519 DLFLWAVLQNRYEMATYFWAMGREGVAAALAACKIIKEMSHLEK----EAEVARTMREAK-YEQLALDLFSECYGNSEDRAFALLVRRNHSWSRTTCLHLATEADAKAFFAHDGVQAFLTKIWW 637          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101])

HSP 1 Score: 68.1662 bits (165), Expect = 4.674e-11
Identity = 130/619 (21.00%), Postives = 244/619 (39.42%), Query Frame = 2
Query:  101 GICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHG--ENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCE---------------------LDINDIYNGYLLYQTETNSYYLENIQTKFESFLKKT---ENINT--------VHIIYDGDFDIFKPVFTTLHDKIPVVLXXXXXXXXXXXXXXXLSEYND--AELNDILR-------------THSNSKELKTISNEIFEFKNSIILYDIKDE-KINLNRKILEALISNTKNTQASDEGFCRRLGNSSKMQESIIY----EWECFEL-SCIFDENSLNENSYLEKTITNDDK-------NKIEVMLFTVLKNNKAKALEWLMKII---NTTDDYVDESFLTRLYHDSVTGNVSCVKELRKR----YDNLSGLKSQTNSFCCKRKQQSAGIPENESFVGTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDY-KNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDK 1747
            G  NK  Y  V  D + +    L   ++ K W+   PK++IS+HG  +N +L   K  + F + LI     T  WI T G   GV   V +A++++   +   K   +GI      EN E                       +N +++ ++L    T   Y    + K    L+K    + INT        V +I +G  ++   V   L D  PV ++       +   +    +Y++    +N+ LR             T + ++ L  I  E  + K  I ++ +  E   +++  IL AL+    N  A D+       N   +  S I+    +W    L   + D   L+   +++  I N          +++E +  T  ++  +  L  L++ +   N   DY        L  + + G        RKR    Y NL G K         RK       E +  +   E N+  + +  EL +WA+L    ++A   W+   + +  AL      K + ++  +N  +D  ++++   S+ +  LA ++++ +Y +    A++L+   L  W N +CLQ++V    ++F + +  +      W  +
Sbjct:  148 GHSNKAMYVRVSFDTKPD----LLLHLMTKEWQLELPKLLISVHGGLQNFELQP-KLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKS-RGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA-NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNT--RHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPF-HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGR 754          

HSP 2 Score: 65.0846 bits (157), Expect = 4.314e-10
Identity = 54/205 (26.34%), Postives = 105/205 (51.22%), Query Frame = 2
Query: 1826 SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKL-KLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFES 2437
            +P  K+W Y ++Y  +++ F Y        I LVK+ +     E  V  Y+F L +E++++I   E   L  + +   +  WN+ D++ I LF + MI R    + +    R +  V +  + +R L  F + +  G  ++MI KM++++  F+ +  + ++++G   Q+I  PN +    L  +IF  PY+ +YGE+  D+ + 
Sbjct:  858 APIVKFWFYTLAYIGYLMLFNY--------IVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQ-DQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDP 1053          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. UniProt/SwissProt
Match: sp|A7T1N0|TMP2L_NEMVE (Transient receptor potential cation channel subfamily M member-like 2 OS=Nematostella vectensis OX=45351 GN=TRPM2 PE=1 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 6.893e-19
Identity = 70/218 (32.11%), Postives = 115/218 (52.75%), Query Frame = 2
Query: 1820 FFS-PTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELG---AEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNP-------NRKWDISLLVDIFLYPYFQMYGELKIDKFESE 2440
            F+S P SK+    + Y  FI  F+Y   VL         K   G    EI ++ +VF +L+EEI+Q+A K  K +  +   ++   WN  DI  + +F +++I RF  +   F  SR + ++ +  FI+RSLQ F + +  G K++MI+KM+ +L  F+ +  +F +AYG    ++  P       N  W    +  +  YPY+QMYGEL +D+ + E
Sbjct:  833 FYSAPFSKFVGNVVGYLAFI--FLYAYVVLFNFPRFDPAKTLGGIHPTEIVLYFWVFTILIEEIRQLAAKPPKYIKDKVSVYFSDTWNFVDIFSLTVFIIAIILRFFTNSRIFTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTW--VTITSVVQYPYWQMYGELFLDEIQGE 1046          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. UniProt/SwissProt
Match: sp|E9PTA2|TRPM2_RAT (Transient receptor potential cation channel subfamily M member 2 OS=Rattus norvegicus OX=10116 GN=Trpm2 PE=1 SV=3)

HSP 1 Score: 80.1073 bits (196), Expect = 7.276e-14
Identity = 87/373 (23.32%), Postives = 167/373 (44.77%), Query Frame = 2
Query: 1364 IEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNR-------------------GXXXXXXXXXXXXXXXRIFF-SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQI-ANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELK 2419
            + +L IWA++  + E+A ++W    D    AL  +  LK++    K +    S+E++   + ++E  A  +    Y K   RA +L+ R    WG  +CLQ+++     +F S    + +    WW +   +N                      ++++     +    R FF +P   ++L  +SYF F+  F YV  V  +P            E  ++L++F L+ EE +Q+  + +G  L      ++   WN  D+  I LF   + CR      Y    R + ++   +F LR +  F I +  G KII++K+M+ ++F FL L  ++++++G   Q+I   N      +   +  + Y  ++G++ 
Sbjct:  621 VRDLLIWAIIQNHRELAGIIWAQSQDCTAAALACSKILKELS---KEEEDTDSSEEMLALADEFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLFTGFISFREKRLQALCRLARVRAFFNAPVVIFYLNILSYFAFLCLFAYVLMVDFQPSP-------SWCEYLIYLWLFSLVCEETRQLFYDPDGCGLMKMASLYFSDFWNKLDVGAILLFIAGLTCRLIPATLY--PGRIILSLDFIMFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNESRVDWIFRGVIYHSYLTIFGQIP 981          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. UniProt/SwissProt
Match: sp|Q91YD4|TRPM2_MOUSE (Transient receptor potential cation channel subfamily M member 2 OS=Mus musculus OX=10090 GN=Trpm2 PE=1 SV=2)

HSP 1 Score: 77.411 bits (189), Expect = 4.885e-13
Identity = 86/373 (23.06%), Postives = 167/373 (44.77%), Query Frame = 2
Query: 1364 IEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNR-------------------GXXXXXXXXXXXXXXXRIFF-SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQI-ANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELK 2419
            + +L IWA++  + E+A ++W    D    AL  +  LK++    K +    S+E++   + ++E  A  +    Y K   RA +L+ R    WG  +CLQ+++     +F S    + +    WW +   +N                      ++++     +    R FF +P   + +  +SYF F+  F YV  V  +P            E  ++L++F L+ EE +Q+  + +G  L      ++   WN  D+  I LF + + CR      Y    R + ++   +F LR +  F I +  G KII++K+M+ ++F FL L  ++++++G   Q+I   N      +   +  + Y  ++G++ 
Sbjct:  620 VRDLLIWAVIQNHRELAGIIWAQSQDCTAAALACSKILKELS---KEEEDTDSSEEMLALADEFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLFTGFISFREKRLQALCRPARVRAFFNAPVVIFHMNILSYFAFLCLFAYVLMVDFQPSP-------SWCEYLIYLWLFSLVCEETRQLFYDPDGCGLMKMASLYFSDFWNKLDVGAILLFIVGLTCRLIPATLY--PGRIILSLDFIMFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNESRVDWIFRGVVYHSYLTIFGQIP 980          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. UniProt/SwissProt
Match: sp|O94759|TRPM2_HUMAN (Transient receptor potential cation channel subfamily M member 2 OS=Homo sapiens OX=9606 GN=TRPM2 PE=1 SV=2)

HSP 1 Score: 77.411 bits (189), Expect = 5.181e-13
Identity = 90/374 (24.06%), Postives = 164/374 (43.85%), Query Frame = 2
Query: 1364 IEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDK-ELPNNRGXXXXXXXXXXXXXXXRIFF--------------------SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQI-ANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELK 2419
            I +L IWA++    E+A ++W    D I  AL  +  LK++    K +    S+E++   +++YE  A  +    Y K   RA +L+ R    WG  +CLQ+++     +F S    + +    WW +  + N         +         I F                    +P   + L  +SYF F+  F YV  V  +P+           E  ++L++F L+ EE++Q+  + +   L  +   ++   WN  D+  I LF   + CR      Y    R + ++   LF LR +  F I +  G KII++K+M+ ++F FL L  ++++++G   Q+I   N +    L      + Y  ++G++ 
Sbjct:  622 IRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELS---KEEEDTDSSEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVP-------SWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLY--PGRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIP 983          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. UniProt/SwissProt
Match: sp|Q93971|TRPG_CAEEL (Transient receptor potential channel OS=Caenorhabditis elegans OX=6239 GN=gon-2 PE=1 SV=4)

HSP 1 Score: 72.4034 bits (176), Expect = 1.873e-11
Identity = 55/207 (26.57%), Postives = 95/207 (45.89%), Query Frame = 2
Query: 1820 FFS-PTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFES 2437
            F+S P S +W + IS+ +FI  F Y   V   P   V        E  +  YV    +E++++I   + K  Y + + +    WN   IL I  + +    R      Y    R + A    L+ ++ L +  +  K G  + M  KM+  +   + +  + +L++G   QSI  P+  W   L+ +IFL PYF +YGE+  D+ ++
Sbjct: 1302 FYSAPISTFWSWTISFILFITFFTYTLLVKTPPRPTV-------IEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCFGSVAY---GRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDT 1498          

HSP 2 Score: 53.9138 bits (128), Expect = 7.150e-6
Identity = 29/131 (22.14%), Postives = 67/131 (51.15%), Query Frame = 2
Query: 1328 GTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCS-AEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACE 1717
            G+    + +Y Y  EL IWA+L+   ++A  +W+   + +  AL      K +  +     L+    E++ K ++++ +L+ ++++  Y     + ++L+   L+ W N++CL ++V  + K F +   C+
Sbjct:  942 GSQTEPDFRYPY-SELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQ 1071          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. TrEMBL
Match: T2MHH2 (Transient receptor potential cation channel subfamily M member 2 (Fragment) OS=Hydra vulgaris OX=6087 GN=TRPM2 PE=2 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 1.351e-23
Identity = 130/475 (27.37%), Postives = 221/475 (46.53%), Query Frame = 2
Query: 1073 LFTVLKNNKAKALEWLMKIINTTDDYVDESFLTRLYHDSVTGNVSCVKELRKRY-----------------DNLSGLKSQTNSFCCKRKQQSAGIPENESFVGTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKV-ENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNRGXXXXXXXXXXXXXXXRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLEL-GAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHE----DYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDK 2428
            +FT L +NK   +E   +       Y+  + L  LY+    G  + ++ L K+Y                 +NL G     + F   R + S   P  +S    S +N        +LF WA+L    E+A+++WK   D I TAL  +  LK + E    NK L    E I + +  YE LA  ++E     +   A  L+ + +  +G  SCL I+V+ + ++F + S+C+    L  +D E P                K    + +P  K+ +  ISY  F+  F +V         L+  ++E+  +E  +  + F LL EEI Q+   E  T Y +   +    WN F+IL +  F L  I R+  ++    +Y +I+R + A  + +FI+R L+ + + +  G K++MI+KML +L  FL +F +F++ +G   Q + +PN +      V IF +PY+ +YG+L  D+
Sbjct:  171 MFTALSDNKPDFVELFFEEGLNLKFYLKMNELLNLYNGVPNG--TALRHLMKKYMGDATEIYDMIVIGSVIENLMG-----DHF---RSRYSTDYPYCQSNYEKSTSNKDLPSPYLDLFTWAVLLNRKELAYLIWKRTRDSIATALMASKLLKSLAEKVQDNKELSDMVEDIIQHAVFYENLAVGVLEECRKDNEEEAQTLLVKEIPEFGFLSCLDIAVSANNQDFIAHSSCQTLLILHDFDDE-PE---AFSAHEKHGFFLKMIHFYNAPFVKFIVNLISYASFLALFAFV--------ILLHFRIEIHNSEYVLQFWAFTLLCEEIHQLIIGESDTFYGKMTIYCSNPWNTFEILALNGFLLGTIYRYLANKYLNFNYLIIARIIYAFDIMIFIIRMLKIYSVNRNMGPKLVMIRKMLRDLSYFLMIFAVFLIGFGVAQQVLLHPNSQ-PYKAFVGIFNHPYWYIYGQLNFDE 622          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. TrEMBL
Match: A0A2R2MLZ3 (transient receptor potential cation channel subfamily M member 3 OS=Lingula unguis OX=7574 GN=LOC106160094 PE=4 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 2.590e-22
Identity = 100/370 (27.03%), Postives = 183/370 (49.46%), Query Frame = 2
Query: 1367 EELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNR-------------GXXXXXXXXXXXXXXXRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGA-EIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRI-CWNXXXXXXXXXXXXSMICRF-SIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDK 2428
            +ELF+WA+     E+A  LW+   D + TAL G++   K+  +   +N +   +   K    +E+LA  ++E  Y+    +A++LI+R    WG ++CL+++   + K F S   C++     W  + L ++                + +K      EK  + F SP  K+ ++ + Y  F+V + Y        + L  L+ E+   EI +  ++  ++VEE++++     +++  +    W    WN  DI++  +     I R      D   +   +N V   LF LR L+ + +    G K++MIK M++EL IF+C+  + I+ YG  +Q++  P R+    +L DIF YPY+Q+YGEL +D+
Sbjct:  654 KELFLWAVFFNRQELALYLWESGDDAVVTALVGSMLYGKLAENTDTRNNELK-DAYLKNKDTFEILAENVLEECYNADEEKALQLIDRHYTDWGQQNCLEVAAAANCKAFLSTECCQNQLNQMWKGQVLSSSLKIYFALVFPPIFFSVRWKKKGLKIHEKIMQFFKSPMVKFSIHLLWYVFFLVAYSY--------LILFHLREEISTLEILLIGWISTMIVEELREMTYSTSESVGGKLIDWWNFSVWNRIDIILCVVALGGFIFRMIPGMLDQIKLFYAMNCV---LFYLRFLRLYSVSSVLGPKLVMIKLMVIELSIFVCILIIAIMGYGVTYQALTFPAREPYWGILKDIFYYPYWQIYGELFLDE 1011          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. TrEMBL
Match: A0A3Q3E8Y3 (Transient receptor potential cation channel subfamily M member 4 OS=Labrus bergylta OX=56723 GN=TRPM4 PE=4 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 6.729e-21
Identity = 97/388 (25.00%), Postives = 178/388 (45.88%), Query Frame = 2
Query: 1373 LFIWALLSGYTEVAFVLWKFCSDLIGTALKGA---INLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWD--------------------------KELPNNRGXXXXXXXXXXXXXXXRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSI---KNPNRKWDISLLVDIFLYPYFQMYGELKIDKFESE 2440
            LFIWA+L   +E+A   W+   + + +AL G      L ++E + +NK    S +++   ++++E LA  +    Y  S  R+  L+ R    WG  +CLQ++   D + F S    +      WW                           K  P+N              ++++ +F+P + +    + YF+F+  F YV  V  KP      K     E  ++ +VF L+ EEI+Q+   +   L +    + +  WN FD   I LF L++ CR  +  + +   R + A+   +F LR +  F I ++ G KII++ KM+ ++F FL    ++++AYG   Q++    +P   W   +   +F  PY  ++G++ ID+ +++
Sbjct:  543 LFIWAVLQNRSEMAIYFWEMAGESVLSALSGCKILRELSRLEIETENK---VSMKEL---AQRFEDLAQDVFGECYQNSESRSFTLLIRTSPVWGGATCLQMATAADARLFFSHDGVQSLLSQIWWGDMERSTEVWKLVLTFFLPPLLYTKLIKPSPSN------SKRPFILSRWRQFWFAPVTSFLGNVLMYFLFLCLFAYVLLVDFKP---PPPKGPSTLEFVLYFWVFTLVCEEIRQVRRSDAANLKNIHHNYIQDVWNKFDFTAISLFMLALCCR--MFPESYEFGRAVMAIDFLVFTLRLIHIFAIHKQLGPKIIIVGKMMKDVFFFLFFLAVWLMAYGVANQALLYPYDPRPNW---IFRRVFYRPYLHIFGQIPIDEMDAD 910          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. TrEMBL
Match: A0A553PIB4 (Uncharacterized protein OS=Tigriopus californicus OX=6832 GN=TCAL_07930 PE=4 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 2.205e-20
Identity = 198/859 (23.05%), Postives = 346/859 (40.28%), Query Frame = 2
Query:  209 PKVVISIHGENKQLN-SNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENR-----QDNILDKTILLGIKRHVFEENCELDINDIYN--GYLLYQT----------------------ETNSYY-----LENIQTKFESFLKKTE----NINTVHIIYDGDFDIFKPVFTTLHDKIPVVLXXXXXXXX-------------XXXXXXXLSEYNDAELNDILRTH---------SNSKELKTISN---EIFEFKNSIILYDIKDEKINLNRKILEALISNTKNTQASDEGFCRRLGNSSKMQESIIYEWECFELSCIFDENSLNENSYLEKTITNDDKNKIEVMLFTVLKNNKAKALEWLMKIINTTDDYVDESFLT-----RLYHDSVTGNVSCVKELRKRYDNLSG------------------LKSQTNSFCCKRKQQSAGIPENESFVGTSEANNKKY--IYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESK-KYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEH---------YARLAW-------------WDKELPNNRGXXXXXXXXXXXXXXXRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELG-AEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRK--WDI--SLLVDIFLYPYFQMYGELKIDKFE 2434
            P + +S+ G  K      +  + FK+ LI   K T   I+T G   G  +LV +A+ E +      D +     L+G+    + ++ +L IND  N   Y+ Y +                      +  S Y       N  TKFE+ ++  E     I  V ++ +G  D  + V   L + I  V+IE S  A                +    + E + A L  +L T          +  +++K I N   E     + I ++DI+ E   L+ KIL AL+ +                ++  + + + +       + I+D   L E   L K   N   +  E+ML   L   +   +E L+      + +V  +FLT     RLY++S        +EL  +  NL G                  LK   +S       Q    P+NE      + + K +   Y+E LF+WA+ +    +    WK C   +  A+       K+ N Y+  N D    KI  + K +++  A  ++E AY+  P +   L+ +   RWG ++ +Q+     L+ F +   C+          + +L W             W   +    G   +    +  +K    + +P  KY    IS+   I  + YV        +L   + +   AE+ ++ +V  L+V+E +++  +  K L  +   H    WN FD +I  +  ++++ +  +    F +SR + AV  S F +R  + +   +  G K+++  +M+ E+  F+ L  +FILAYG   Q+I +P R+  W+    LL  I   PY+QMYGEL +D  E
Sbjct:  347 PHLALSLIGGAKNFRMEGRKKETFKKGLISAAKSTNALILTGGTNTGTMKLVGDAIREGQFMVQNGDKLSRGLKLMGLCSFGYIKDRDLLINDNPNEFNYVRYNSNQEIKKGDNVPLNGDHTHFIMVDDGSRYRFFSGYTNFITKFETMIRDPEPQGLGIPIVTLLLEGGKDAIRIVKDRLKEGIACVVIEGSGRAADIISYAYRNAVKNPKTNTYTMKEGHIAHLMKMLETAYGTYIKPKAARDEQMKDIMNWTIECISHSDIITIFDIRRE-TQLDTKILSALLKS----------------DNMSLHQQLFF-------AMIWDRIDLAEEKILVKDTLNTMDSLHEIML-QALVLERTNFIELLV-----MNGFVMRTFLTVERLRRLYNESTLR----WRELHFQMKNLVGIPCNEIYLRNIHKLLVTLLKDHDHSL-----YQLDRPPKNEKKHRRVDVSTKTFEEPYVE-LFLWAIFTNKQSLIDFCWKRCGQPMLMAIVAGAIYSKMGNFYRRYNKDI---KILTDRKAQFQKRANMLMEIAYEADPNKGYSLLEKRNKRWGGRNFMQLGYIGHLRTFIANPTCQSVVNSNWIRGFLKLPWFSCLICLILPFLTWTPIVTFMGGLGDDGGKLTWFQKLYVFYRAPVVKYTGTCISFLALITLYSYV--------ALYGYRNDFQMAELILYTWVAILIVDECREVVMEPSKKLSGKLSDHMDSVWNKFDFIIYSIMVINIVLK--LFPATFEVSRVIFAVNCSFFYIRVFRIYHASRSLGPKLVIFHRMIPEIITFMFLLIVFILAYGVANQAIIDPYRQFQWNSFWKLLFQIVFLPYWQMYGELSLDSIE 1152          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. TrEMBL
Match: A0A1L3INW2 (Transient receptor potential cation channel subfamily M member 3 OS=Homarus americanus OX=6706 PE=2 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 4.739e-20
Identity = 136/586 (23.21%), Postives = 247/586 (42.15%), Query Frame = 2
Query:  803 NSIILYDIKDEKINLNRKILEALISNTKNTQASDEGFCRRLGNSSKMQESIIYEWECFELSCIFDENSLNENSYLEKTITNDDKNKIEVMLFTVLKNNKAKALEWLMKIINTTDDYVDESFLTRLYHDSVTGNVSCVKEL-RKRYDNLSGLKSQTNSFCCKRKQQSAGIPENESFVGTSEANNKKYIYIE----ELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAW-----------------------WDK-----ELPNNRGXXXXXXXXXXXXXXXRIFF-SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELG-AEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDI-------SLLVDIFLYPYFQMYGELKIDKFE 2434
            N I ++DI   + ++++ IL AL++    T   D+                        L+ ++D   + E         N     +E ++ T L   K + ++          DY+    L  LY+++   N   ++ L R   +N   L    N      ++    I  +++    S+  +  Y+  E    EL +WA+ S    +A  LW+ C+  +  A+  +   + +      KN D   E+  K    +E+ A  ++   Y +  I A+ L+ R  A+WGN  CL+++V  +   F S  A +    L W                       W +     +L +N GE               +F+ SP SK+  +  ++ IF++ + YV         L   K E+   E F+F+++   +++EI +I +++  TL  +        WN FDI+   L FL++  R  +H   F   R   AV  ++F  R  + + +    G K+++  +M+ E+ +FL L  +FIL YG   Q++ +P+R           S++ D+ L PY+QMYGEL +D+ E
Sbjct:   52 NMITIFDINSNE-DMDKYILYALLTGEDVTSMQDQ----------------------LSLALLWDRPDIAECEIFPAQ-KNWPSGALEDLMTTALLEEKVEFVKLFTMNGLVMADYLTVKKLRHLYNEACIPNSHLMRLLQRASQNNYHYLFHVHNVLQAMMRRHHDDIYTSDTPQAQSDNPSINYLTFEDPYMELLLWAIFSRRAWLANYLWQRCNSPLCAAIAASCLYQSLWRSLGAKNTDI-LEEYNKNKNTFELFAVNLLGVCYQQDVINALGLVERRNAKWGNSDCLELAVMANDLIFISTPAAQASVELNWRRGMSRAPFFAVIIANVFPLLIFWPRFFRFQKLGDNGGELTIPQKMV-------VFYKSPISKFCAHSTAFVIFLIVYAYV--------VLFDFKYEMSITEKFLFVWICIYVIDEISEIISEQSLTLRGKISDWAGSVWNRFDIVAFFLAFLALGLR--LHRQTFKWGRIAYAVNTNVFYCRLFRMYHVNYHLGPKLVIFYRMISEVLVFLALLVIFILGYGIASQALLHPSRDAGSLNSTSVSSIMEDVLLTPYWQMYGELLLDEAE 595          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Cavefish
Match: trpm5 (transient receptor potential cation channel subfamily M member 5 [Source:NCBI gene;Acc:103047602])

HSP 1 Score: 68.1662 bits (165), Expect = 3.165e-11
Identity = 54/209 (25.84%), Postives = 111/209 (53.11%), Query Frame = 2
Query: 1814 RIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQ-IANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFES 2437
            R + +P + +    + YF F+V F YV  +  +P       +   AEI ++ +VF L++EEI+Q     E   +  + + +    WN  D++ I LF + + CR  + E+ +   R + A+   +F LR +  F I ++ G KII++++M+ ++F FL    ++++AYG   Q++ +PN      +   +   PY  ++G++ +++ ++
Sbjct:  761 RFWSAPVTVFLGNVLMYFAFLVLFTYVLLLDFRPPPPDGPSI---AEIILYFWVFTLVLEEIRQSFFTDEDMNILKKCKLYVEDNWNKCDMVAISLFVVGVSCR--MMENTYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLIAYGVATQALLHPNDPRLDWVFRRVLYRPYLHIFGQIPLEEIDA 964          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571])

HSP 1 Score: 64.6994 bits (156), Expect = 4.846e-10
Identity = 51/200 (25.50%), Postives = 101/200 (50.50%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKL-ELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGEL 2416
            + +P  K+W   + Y +F++ + YV         LVKL +     E  V LY+F   +E+I+++   EG  +  + +  +   +N  D + I +F +    RF    + F+  R +  + +  + +R L    + Q+ G  ++MI KM+  +F  + +  + ++ YG   ++I  PN + + SL++D+   PY+ MYGE+
Sbjct:  819 YHAPIVKFWTNTLFYLVFLMLYSYV--------VLVKLPIFPSPQEWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFSDYFNRSDFIAIVMFAVGFGLRFG-SGNVFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYGEV 1009          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571])

HSP 1 Score: 64.3142 bits (155), Expect = 5.318e-10
Identity = 51/200 (25.50%), Postives = 101/200 (50.50%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKL-ELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGEL 2416
            + +P  K+W   + Y +F++ + YV         LVKL +     E  V LY+F   +E+I+++   EG  +  + +  +   +N  D + I +F +    RF    + F+  R +  + +  + +R L    + Q+ G  ++MI KM+  +F  + +  + ++ YG   ++I  PN + + SL++D+   PY+ MYGE+
Sbjct:  862 YHAPIVKFWTNTLFYLVFLMLYSYV--------VLVKLPIFPSPQEWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFSDYFNRSDFIAIVMFAVGFGLRFG-SGNVFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYGEV 1052          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571])

HSP 1 Score: 64.3142 bits (155), Expect = 5.771e-10
Identity = 51/200 (25.50%), Postives = 101/200 (50.50%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKL-ELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGEL 2416
            + +P  K+W   + Y +F++ + YV         LVKL +     E  V LY+F   +E+I+++   EG  +  + +  +   +N  D + I +F +    RF    + F+  R +  + +  + +R L    + Q+ G  ++MI KM+  +F  + +  + ++ YG   ++I  PN + + SL++D+   PY+ MYGE+
Sbjct:  845 YHAPIVKFWTNTLFYLVFLMLYSYV--------VLVKLPIFPSPQEWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFSDYFNRSDFIAIVMFAVGFGLRFG-SGNVFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYGEV 1035          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571])

HSP 1 Score: 64.3142 bits (155), Expect = 5.785e-10
Identity = 51/200 (25.50%), Postives = 101/200 (50.50%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKL-ELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGEL 2416
            + +P  K+W   + Y +F++ + YV         LVKL +     E  V LY+F   +E+I+++   EG  +  + +  +   +N  D + I +F +    RF    + F+  R +  + +  + +R L    + Q+ G  ++MI KM+  +F  + +  + ++ YG   ++I  PN + + SL++D+   PY+ MYGE+
Sbjct:  855 YHAPIVKFWTNTLFYLVFLMLYSYV--------VLVKLPIFPSPQEWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFSDYFNRSDFIAIVMFAVGFGLRFG-SGNVFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYGEV 1045          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Sea Lamprey
Match: trpm2 (transient receptor potential cation channel, subfamily M, member 2 [Source:NCBI gene;Acc:799412])

HSP 1 Score: 95.5153 bits (236), Expect = 2.813e-20
Identity = 99/388 (25.52%), Postives = 172/388 (44.33%), Query Frame = 2
Query: 1367 EELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKV--ENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNRGXXXXXXXXXXXXXXXRI--------------------FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQI-ANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRF---SIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFESEFYAT 2452
             +LFIWA+L    E+A   W    D +  AL  +  LK +  E D  ++  D     +  ++  YE LA  +++  Y    +RA +L+ R L  WG  +CL ++ + + K F S S  +      WW     + +  +    I      + RI                    + +P + +W   +SYFIF+  F YV       I +         E  ++ +V  L++EE++Q+  + E    +    ++ +  WN  DIL + LF + +ICR    SI+E  F   R +  V   +F LR +  F + +  G KII++K+M+ ++F FL L  ++++AYG   Q I   N +    +   +   PY  ++G+       + F  T
Sbjct:  551 RDLFIWAVLLNRRELANFFWSQGKDCMAAALMASKLLKAMVQEEDDSDRTSD-----MLAQADNYEQLAIGLLDECYKDDELRAQKLLIRQLHSWGGATCLSMAYHANNKSFFSHSGVQALLTQIWWGGMSVDLKTWRVILCIIFPLLIYTRIITFRWVLYAHTCTPTRWRNFWTAPITVFWANVVSYFIFLWLFAYV-------IIMDFQYTPDWPEYVLYAWVLSLILEELRQVFTDPEKAGQWKAAVRYIKDIWNRIDILALLLFTIGVICRLIPNSINESTFQAGRSVLCVDYMVFCLRLMHIFTVNKTLGPKIIIVKRMVKDIFFFLFLLGVWVVAYGVATQGILILNEQRLDWIFRGVVYQPYLLIFGQFPTRVDSTTFDTT 926          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Sea Lamprey
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2])

HSP 1 Score: 49.6766 bits (117), Expect = 2.822e-6
Identity = 53/201 (26.37%), Postives = 100/201 (49.75%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSI--KNPNRKWDISLLVDIFLYPYFQMYGEL 2416
            + +P  K+W   ++Y  F++ F YV  V L+ +  V+       E FV LY+F   +E +++I   E      + +      WNI D L I LFF+++  R   H    + ++ + ++ +  + +R L  F + Q  G  I+MI KM+ +  + + +  + +L++G   Q+I  K  +  W   L  +I   PY+ ++GE+
Sbjct:  730 YHAPIVKFWFNTLAYIGFLMLFTYVVLVKLQQLPSVQ-------EWFVILYLFMSAIERVREIFMSEPGKFGQKIKVWLDGYWNINDSLGILLFFVAVALRSQSH--LLIEAKIVYSLDVIFWYVRLLDVFAVNQNVGPYIMMIGKMMWQQCMLMIIMAIVLLSFGVARQAILFKEADPSW--YLARNIVFQPYWMIFGEV 919          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Nematostella
Match: EDO30135 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1N0])

HSP 1 Score: 93.2041 bits (230), Expect = 3.176e-19
Identity = 68/217 (31.34%), Postives = 114/217 (52.53%), Query Frame = 2
Query: 1820 FFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELG---AEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNP-------NRKWDISLLVDIFLYPYFQMYGELKIDKFESE 2440
            + +P SK+    + Y  FI  F+Y   VL         K   G    EI ++ +VF +L+EEI+Q+A K  K +  +   ++   WN  DI  + +F +++I RF  +   F  SR + ++ +  FI+RSLQ F + +  G K++MI+KM+ +L  F+ +  +F +AYG    ++  P       N  W    +  +  YPY+QMYGEL +D+ + E
Sbjct:  834 YSAPFSKFVGNVVGYLAFI--FLYAYVVLFNFPRFDPAKTLGGIHPTEIVLYFWVFTILIEEIRQLAAKPPKYIKDKVSVYFSDTWNFVDIFSLTVFIIAIILRFFTNSRIFTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTW--VTITSVVQYPYWQMYGELFLDEIQGE 1046          

HSP 2 Score: 49.6766 bits (117), Expect = 6.073e-6
Identity = 33/101 (32.67%), Postives = 48/101 (47.52%), Query Frame = 2
Query:   86 DLFKLGICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHGENKQ-LNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENR 385
            D    G   + PY  +  D +   +  L    +LKRW    P +VIS+ G  K  +   +  + F++ LI   K T  WIIT G   GV + V EAV+E +
Sbjct:   99 DFEGYGGQKRAPYLRMSHDTDANLVITL----MLKRWNLEIPNLVISVTGGAKSFVLKPRLREMFRRGLIKAAKTTGAWIITGGTNTGVMKHVGEAVKEQQ 195          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Nematostella
Match: EDO47658 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLT7])

HSP 1 Score: 66.6254 bits (161), Expect = 3.979e-11
Identity = 62/209 (29.67%), Postives = 111/209 (53.11%), Query Frame = 2
Query: 1826 SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTL----YSRFQK-HWRI-CWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFE 2434
            +P +K+W   I Y +F+V F +V  + L P+  ++  + +G       +VF L  EE++Q+     + +    +S F+   W    WN+ D   + LFFL++  R  ++     I   + ++ + L+I+R L  F + +  G  ++MI +M +++  FL +  +F+LAYG   Q+I  P+ K    L+  IF  PYFQ+YGEL I+  +
Sbjct:  765 APITKFWSNLIVYLLFLVVFSHVILIELPPVPSIEEWVLIG-------FVFSLCAEEVRQV-----RVINVWNFSFFESSDWASNVWNLCDGFAMVLFFLAVGLR--LNPGTLRIGHLVYSLDIMLWIIRLLDIFSVSKDLGPYVVMIGRMTIDMMYFLVIMVVFLLAYGVAQQAILFPHEKPSWELITKIFFRPYFQVYGELFIEDVD 959          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Medaka
Match: hrc (transient receptor potential cation channel subfamily M member 4 [Source:NCBI gene;Acc:101158642])

HSP 1 Score: 75.0998 bits (183), Expect = 2.830e-13
Identity = 59/213 (27.70%), Postives = 113/213 (53.05%), Query Frame = 2
Query: 1814 RIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSI-----KNPNRKWDISLLVDIFLYPYFQMYGELKIDKFES 2437
            + +F+P + +    + YF+F+V F YV  V  KP       +   +E  ++ +VF ++ EEI++ A    +    R + + +  WN  DI+ I LF + +ICR  ++E  +   R +  V   +F LR +  F I ++ G KII++ KM+ ++F FL    ++++AYG   Q++      NP+R     +   +F  PY  ++G++ +++ +S
Sbjct:  831 QFWFAPVTSFLGNVLMYFLFLVLFAYVLLVDFKPQPPWGPAV---SEYVLYFWVFTIVCEEIRETAFLGTRNWRQRLRSYIQDVWNKIDIVAITLFIVGLICR--MYERSYEFGREVLCVDYMVFTLRLIHIFAIHKQLGPKIIIVGKMMKDVFFFLFFLGVWLIAYGVANQALIYSYDSNPDR-----IFRRVFYRPYLHIFGQIPVEEIDS 1033          

HSP 2 Score: 57.3806 bits (137), Expect = 6.761e-8
Identity = 38/144 (26.39%), Postives = 65/144 (45.14%), Query Frame = 2
Query: 1322 FVGTSEANNKKYIYI-EELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLK---KVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWW 1741
             VG S+   ++ +Y    LFIWA+L    E+A   W+   + +  AL G   L+   K+E + + K        + + ++ +E LA+ I  + Y     RA  L+ +    WG  +CLQ+ +  D + F S    +      WW
Sbjct:  589 LVGESKYREERCVYPWASLFIWAILQRRNEMATFFWEMAGESVLCALSGCKMLREMSKLETETEGK------LSLKEMAQSFENLAHDIFSSCYHSDENRAFTLLIKKSPVWGGTTCLQMGMGGDTRLFFSHDGVQSLLSQIWW 726          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Medaka
Match: ENSORLT00000029710.1 (transient receptor potential cation channel subfamily M member 4 [Source:NCBI gene;Acc:101156498])

HSP 1 Score: 71.2478 bits (173), Expect = 4.488e-12
Identity = 59/212 (27.83%), Postives = 108/212 (50.94%), Query Frame = 2
Query: 1814 RIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSI---KNPNRKWDISLLVDIFLYPYFQMYGELKIDKFESE 2440
            + +F+P + +    + YF+F+  F YV   LL              EI ++ +VF L+ EEI+Q    +G  L  + + + +  WN  D+  I LF L + CR      YF   R + AV   +F LR +  F + ++ G KII++ KM+ ++F F+    +++LAYG   Q++    +P   W   +   +F  PY  ++G++ I++ +++
Sbjct:  828 QFWFAPVTSFLGNVLMYFLFLGLFAYV---LLVDFKPPPPDGPSPLEIVLYFWVFTLVCEEIRQSFFVDGLFLLQKMKNYIQDVWNKCDLTAIILFILGVCCRMFPASYYF--GRGVMAVDFLVFTLRLIHIFAVHKQLGPKIIIVGKMVKDVFFFMFFLAVWLLAYGVANQALLYSYDPRSTW---IFRRVFYRPYMHIFGQIPINEMDAD 1031          

HSP 2 Score: 57.7658 bits (138), Expect = 4.852e-8
Identity = 35/126 (27.78%), Postives = 61/126 (48.41%), Query Frame = 2
Query: 1373 LFIWALLSGYTEVAFVLWKFCSDLIGTALKGA---INLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWW 1741
            LFIWA+L    ++A   W+   + + +AL G      L K+E++ ++K       ++ K ++K+E LA+ +    Y  S   A  L+ R    WG  +CLQ++   D + F S+   +      WW
Sbjct:  612 LFIWAVLQNRPKMAVFFWEMAGESVMSALAGCKILRELSKLEDETESK------LEMKKLAQKFEDLAHDVFGNCYQNSETLAFTLLIRKSPVWGKATCLQMATAADARLFFSQDGVQFLLSQIWW 731          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Medaka
Match: ENSORLT00000021513.2 (transient receptor potential cation channel subfamily M member 4 [Source:NCBI gene;Acc:101156498])

HSP 1 Score: 71.2478 bits (173), Expect = 4.517e-12
Identity = 59/212 (27.83%), Postives = 108/212 (50.94%), Query Frame = 2
Query: 1814 RIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSI---KNPNRKWDISLLVDIFLYPYFQMYGELKIDKFESE 2440
            + +F+P + +    + YF+F+  F YV   LL              EI ++ +VF L+ EEI+Q    +G  L  + + + +  WN  D+  I LF L + CR      YF   R + AV   +F LR +  F + ++ G KII++ KM+ ++F F+    +++LAYG   Q++    +P   W   +   +F  PY  ++G++ I++ +++
Sbjct:  894 QFWFAPVTSFLGNVLMYFLFLGLFAYV---LLVDFKPPPPDGPSPLEIVLYFWVFTLVCEEIRQSFFVDGLFLLQKMKNYIQDVWNKCDLTAIILFILGVCCRMFPASYYF--GRGVMAVDFLVFTLRLIHIFAVHKQLGPKIIIVGKMVKDVFFFMFFLAVWLLAYGVANQALLYSYDPRSTW---IFRRVFYRPYMHIFGQIPINEMDAD 1097          

HSP 2 Score: 57.7658 bits (138), Expect = 4.991e-8
Identity = 35/126 (27.78%), Postives = 61/126 (48.41%), Query Frame = 2
Query: 1373 LFIWALLSGYTEVAFVLWKFCSDLIGTALKGA---INLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWW 1741
            LFIWA+L    ++A   W+   + + +AL G      L K+E++ ++K       ++ K ++K+E LA+ +    Y  S   A  L+ R    WG  +CLQ++   D + F S+   +      WW
Sbjct:  678 LFIWAVLQNRPKMAVFFWEMAGESVMSALAGCKILRELSKLEDETESK------LEMKKLAQKFEDLAHDVFGNCYQNSETLAFTLLIRKSPVWGKATCLQMATAADARLFFSQDGVQFLLSQIWW 797          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Medaka
Match: ENSORLT00000000453.2 (pep primary_assembly:ASM223467v1:3:5283852:5304338:1 gene:ENSORLG00000000365.2 transcript:ENSORLT00000000453.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 67.781 bits (164), Expect = 3.522e-11
Identity = 56/205 (27.32%), Postives = 104/205 (50.73%), Query Frame = 2
Query: 1826 SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKL-KLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFES 2437
            +P +K+W   ISY ++++ + Y        I LVK+ +L    E  V  Y+  L +E+++QI   E   L  +F       WNI D++ I  F L ++ R    E Y    R +  V +  + +R L  F + +  G  ++MI KM++++  F+ +  + ++++G   Q+I +P+ +    L  +IF  PY+ +YGE+  D  + 
Sbjct:  355 APFTKFWFNTISYLVYLMLYNY--------IILVKMERLPCLQEWIVISYIITLGLEKVRQILMSEPGKLRQKFIVWLEDYWNITDLVAISAFLLGLLLRVQ-REPYMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPDEEPTWRLARNIFYMPYWMIYGEVFADSIDP 550          

HSP 2 Score: 54.6842 bits (130), Expect = 4.779e-7
Identity = 44/186 (23.66%), Postives = 83/186 (44.62%), Query Frame = 2
Query: 1214 KELRKRYDNLSGLKSQ----------TNSFCCKRKQQSAGIPENESFVGTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNL-DCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAW 1738
            K  R  Y+NL GLK              S+  K+K++   I      V   E    +Y +  EL +WA+L    ++A  LW+   + +  AL      K + ++     L D   + +   SK++ +LAY++++ +Y      A++L+   L  W N +CL+++V    ++F + +  +      W
Sbjct:   90 KSFRTLYNNLYGLKRPKALKLLGMEVRRSYKNKKKEEELDID-----VDDPEVCRFQYPF-HELMVWAVLMKRQKMALFLWQRGEEAMAKALVACKLYKAMAHESSQSELVDDIYQDLENNSKEFGLLAYELLDQSYKHDEQVAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMW 269          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Medaka
Match: trpm3 (transient receptor potential cation channel subfamily M member 3 [Source:NCBI gene;Acc:100533512])

HSP 1 Score: 64.6994 bits (156), Expect = 4.346e-10
Identity = 52/205 (25.37%), Postives = 103/205 (50.24%), Query Frame = 2
Query: 1826 SPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKL-ELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFES 2437
            +P  K+W + ++Y  +++ F Y        I LVK+ L     E  V  Y+F   +E++++I   E   L  + +   +  WNI D++ I +F + M+ R      +    R +  + +  + +R L  F + +  G  ++MI KM++++  F+ +  + ++++G   Q+I NPN      L  +IF  PY+ +YGE+  D+ + 
Sbjct:  840 APIVKFWFHTLAYVGYLMLFNY--------IVLVKMDLWPSPQEWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQEYWNITDLMAILIFSVGMVLRLQ-EPPFMSYGRVIYCINIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPNEDPSWMLARNIFFMPYWMIYGEVFADQIDP 1035          

HSP 2 Score: 52.373 bits (124), Expect = 2.827e-6
Identity = 39/182 (21.43%), Postives = 83/182 (45.60%), Query Frame = 2
Query: 1214 KELRKRYDNLSGLKSQTNSFCCKRKQQSAGIPENESF---VGTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDY-KNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDK 1747
            K  R  Y NL G K   +    +R +Q       E     +   E N+  + +  EL +WA+L    ++A   W+   + +  AL      K + ++  +N  +D  ++++   S+++  LA ++++ +Y +    A++L+   L  W N +CLQ++V    ++F + +  +      W  +
Sbjct:  558 KRFRTLYHNLFGPKR--DDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPF-HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFAQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGR 736          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Planmine SMEST
Match: SMESG000004900.1 (SMESG000004900.1)

HSP 1 Score: 836.254 bits (2159), Expect = 0.000e+0
Identity = 454/455 (99.78%), Postives = 455/455 (100.00%), Query Frame = 2
Query: 1070 MLFTVLKNNKAKALEWLMKIINTTDDYVDESFLTRLYHDSVTGNVSCVKELRKRYDNLSGLKSQTNSFCCKRKQQSAGIPENESFVGTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNRGXXXXXXXXXXXXXXXRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFE 2434
            MLFTVLKNNKAKALEWLMKIINTTDDYVDESFLTRLYHDSVTGNVSCVKELRKRYDNLSGLKSQTNSFCCKRKQQSAGIPENESFVGTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNRG+KKEKAIESSKEKFKRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNIFDILIIPLFFLSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMELFIFLCLFFLFILAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFE
Sbjct:    1 MLFTVLKNNKAKALEWLMKIINTTDDYVDESFLTRLYHDSVTGNVSCVKELRKRYDNLSGLKSQTNSFCCKRKQQSAGIPENESFVGTSEANNKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDKELPNNRGKKKEKAIESSKEKFKRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNIFDILIIPLFFLSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMELFIFLCLFFLFILAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKFE 455          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Planmine SMEST
Match: SMESG000005077.1 (SMESG000005077.1)

HSP 1 Score: 545.428 bits (1404), Expect = 0.000e+0
Identity = 287/287 (100.00%), Postives = 287/287 (100.00%), Query Frame = 2
Query:   17 MAINNDVKMNFMETNYGYYNKNKDLFKLGICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHGENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCELDINDIYNGYLLYQTETNSYYLENIQTKFESFLKKTENINTVHIIYDGDFDIFKPVFTTLHDKIPVVLXXXXXXXXXXXXXXXLSEYNDAELNDILRTHSNSKELKTISNEIFEFKNSIILYDIKDEKINLNRKILEALIS 877
            MAINNDVKMNFMETNYGYYNKNKDLFKLGICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHGENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCELDINDIYNGYLLYQTETNSYYLENIQTKFESFLKKTENINTVHIIYDGDFDIFKPVFTTLHDKIPVVLIENSKIANSISKIIELSEYNDAELNDILRTHSNSKELKTISNEIFEFKNSIILYDIKDEKINLNRKILEALIS
Sbjct:    1 MAINNDVKMNFMETNYGYYNKNKDLFKLGICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHGENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCELDINDIYNGYLLYQTETNSYYLENIQTKFESFLKKTENINTVHIIYDGDFDIFKPVFTTLHDKIPVVLIENSKIANSISKIIELSEYNDAELNDILRTHSNSKELKTISNEIFEFKNSIILYDIKDEKINLNRKILEALIS 287          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Planmine SMEST
Match: SMESG000005077.1 (SMESG000005077.1)

HSP 1 Score: 529.635 bits (1363), Expect = 0.000e+0
Identity = 279/279 (100.00%), Postives = 279/279 (100.00%), Query Frame = 2
Query:   41 MNFMETNYGYYNKNKDLFKLGICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHGENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCELDINDIYNGYLLYQTETNSYYLENIQTKFESFLKKTENINTVHIIYDGDFDIFKPVFTTLHDKIPVVLXXXXXXXXXXXXXXXLSEYNDAELNDILRTHSNSKELKTISNEIFEFKNSIILYDIKDEKINLNRKILEALIS 877
            MNFMETNYGYYNKNKDLFKLGICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHGENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCELDINDIYNGYLLYQTETNSYYLENIQTKFESFLKKTENINTVHIIYDGDFDIFKPVFTTLHDKIPVVLIENSKIANSISKIIELSEYNDAELNDILRTHSNSKELKTISNEIFEFKNSIILYDIKDEKINLNRKILEALIS
Sbjct:    1 MNFMETNYGYYNKNKDLFKLGICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHGENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCELDINDIYNGYLLYQTETNSYYLENIQTKFESFLKKTENINTVHIIYDGDFDIFKPVFTTLHDKIPVVLIENSKIANSISKIIELSEYNDAELNDILRTHSNSKELKTISNEIFEFKNSIILYDIKDEKINLNRKILEALIS 279          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Planmine SMEST
Match: SMESG000005077.1 (SMESG000005077.1)

HSP 1 Score: 523.087 bits (1346), Expect = 0.000e+0
Identity = 276/276 (100.00%), Postives = 276/276 (100.00%), Query Frame = 2
Query:   50 METNYGYYNKNKDLFKLGICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHGENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCELDINDIYNGYLLYQTETNSYYLENIQTKFESFLKKTENINTVHIIYDGDFDIFKPVFTTLHDKIPVVLXXXXXXXXXXXXXXXLSEYNDAELNDILRTHSNSKELKTISNEIFEFKNSIILYDIKDEKINLNRKILEALIS 877
            METNYGYYNKNKDLFKLGICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHGENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCELDINDIYNGYLLYQTETNSYYLENIQTKFESFLKKTENINTVHIIYDGDFDIFKPVFTTLHDKIPVVLIENSKIANSISKIIELSEYNDAELNDILRTHSNSKELKTISNEIFEFKNSIILYDIKDEKINLNRKILEALIS
Sbjct:    1 METNYGYYNKNKDLFKLGICNKIPYAIVPDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHGENKQLNSNKDHKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCELDINDIYNGYLLYQTETNSYYLENIQTKFESFLKKTENINTVHIIYDGDFDIFKPVFTTLHDKIPVVLIENSKIANSISKIIELSEYNDAELNDILRTHSNSKELKTISNEIFEFKNSIILYDIKDEKINLNRKILEALIS 276          
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Planmine SMEST
Match: SMESG000017090.1 (SMESG000017090.1)

HSP 1 Score: 256.914 bits (655), Expect = 3.632e-72
Identity = 240/862 (27.84%), Postives = 414/862 (48.03%), Query Frame = 2
Query:  134 PDDIEEERLKCLYNEVLLKRWEFAPPKVVISIHGENKQLNSNKD-HKRFKQMLIDILKLTTMWIITSGNKNGVHELVSEAVEENRQDNILDKTILLGI--------KRHVFEENCELDINDIYNGYL------------LYQTETNSYYLENIQTKFESFLKKTENINTVHIIYDGD------------FDIFKPVFTTLHDKIPVVLXXXXXXXXXXXXXXXLSEYNDAELNDILRTHSNSKELKTISNEIFEFKNSIILYDIKDEKINLNRKILEALISNTKNTQASDEGFCRRLGNSSKMQESIIYEWECFELSCIFDENSLNENSYLE----KTITNDDKNKIEVMLFTVLKNNKAKALEWLMKIINTTDDYVDESFLTRLYHDSVTGNVSCVKELRKRYDNLSGLKSQTN---------------------SFCCKRKQQSAGIPENE-----------SFVGTSEAN-------------------NKKYIYIEELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLDCSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQISVNEDLKEFCSKSACEHYARLAWWDK--------ELPNNRGXXXXXXXXXXXXXXXRIFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVFLYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNXXXXXXXXXXXXSMICRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLMEXXXXXXXXXXXXXAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGELKIDKF 2431
            PD + ++++       LLK      PKV+ISI+G  + ++ +K+  K  KQ   + L     W+I +G   G+H+L+SE V+E+R DN   +  L+G          + V + + + +IN + N  L            LY        L     K+ S LK      T  I++ GD              I+  V      +  V+    +KI ++ +  + + EY      D+ R       L+    E++++++ I++YDIK +   L+++I EA+ S   N                 +++ +IY       S  F E  + +    +    K + N  K  +   L ++LKNNK   LE  ++   + D +++E+ L  LY +S+ G + C K L +++  +  + S  N                     S   + + ++    E+E            F   SE+                    N+ YI  ++LFIWALLS Y EVAF++W+  +D I TAL G+I LK +   + +  L   +EK  KES  Y  +A  ++   ++K+P +A  ++ RP+ RW   SCLQI+VN ++KEFC+ +AC  + + AW  K        +L +N  E K+ ++   +++ KR   +P SK++   ++Y +F++ F+ VN   L  I   K K+E   EI+V+ Y    +VEEI QIAN+E  ++ S+ + H    WN +D+++I L                 I RCL A+TLS+F +RS+QFF I +  G K +MIK+M++++  FL +F +FI+A+G+L Q++++PN     S++ DI   PYF ++G+L ++ +
Sbjct:   51 PDKVPDDKILDKIFGSLLK------PKVIISINGGIEDIDFDKEVEKHLKQTFKEFLIADNQWVIGTGLNCGIHKLISETVQESRFDNEDKQINLIGFYNFSEIESNQSVVKTDKKREINHLSNLKLDPHYNCLIFHEFLYDKPKKELELRKNFEKYCSELKAF----TFQILWGGDELSLDWAINSLMTQIYVVVMKGSGKRADVICSMLNKIDSADNIEMAIQEYCGNLEGDLDR-------LRNQLGELWKYRDKILIYDIKSKTEGLDKQIFEAIKSCLNNN----------------LEKILIY-------SMSFKEQMIKQTGVFKDEKFKNLENKQKRNV---LKSILKNNKPILLELFLENEMSIDMFLEEADLIELYEESINGRIGCSKLLNEKFQEIKRIYSAKNRKKSNDVNNQDCLDQPDANKQSTFNRERIKTPNTDESEKKTEKRNFVRFQFGNKSESKDYHSSKSSHLLMQNIIYEINRNYIESQKLFIWALLSEYFEVAFIIWREGNDHISTALTGSILLKDISKYFID--LSQLSEKYLKESNSYRTMAIHMMAKIFNKNPTKANSILLRPIDRWEKMSCLQIAVNGNVKEFCNLNACHSFTKRAWIGKFEAKTKSRDLFSNNKENKKSSVLQFRKRIKRYLRAPISKFFTNLVAYVLFLLFFMDVNLFRLNEIGKYKRKIEYWTEIYVYAYFLIFIVEEINQIANQEQNSIKSKLKTHLHGIWNFYDLILIILV---------------SIIRCLYAITLSMFWIRSMQFFIISRALGPKFVMIKRMIIDVIFFLFIFLIFIIAFGSLVQALQHPNSHLTYSIINDILFQPYFHVFGDLMLESY 852          
The following BLAST results are available for this feature:
BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TRPM27.602e-1424.06transient receptor potential cation channel subfam... [more]
TRPM29.419e-1424.00transient receptor potential cation channel subfam... [more]
TRPM21.079e-1324.06transient receptor potential cation channel subfam... [more]
TRPM21.079e-1324.06transient receptor potential cation channel subfam... [more]
TRPM52.450e-1126.96transient receptor potential cation channel subfam... [more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gon-21.341e-1226.57Transient receptor potential channel [Source:UniP... [more]
gon-21.346e-1226.57Transient receptor potential channel [Source:UniP... [more]
gon-21.473e-1226.57Transient receptor potential channel [Source:UniP... [more]
gon-21.337e-1125.96Transient receptor potential channel [Source:UniP... [more]
gtl-21.469e-726.21Gon-Two Like (TRP subfamily) [Source:UniProtKB/Tr... [more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Trpm9.742e-925.63gene:FBgn0265194 transcript:FBtr0339077[more]
Trpm1.197e-825.63gene:FBgn0265194 transcript:FBtr0339074[more]
Trpm1.199e-825.63gene:FBgn0265194 transcript:FBtr0339080[more]
Trpm1.226e-825.63gene:FBgn0265194 transcript:FBtr0339076[more]
Trpm1.248e-825.63gene:FBgn0265194 transcript:FBtr0339079[more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trpm62.241e-1421.22transient receptor potential cation channel, subfa... [more]
trpm54.134e-1126.67transient receptor potential cation channel, subfa... [more]
trpm54.255e-1126.67transient receptor potential cation channel, subfa... [more]
trpm54.560e-1126.67transient receptor potential cation channel, subfa... [more]
trpm36.965e-1025.91transient receptor potential cation channel, subfa... [more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shc28.162e-1922.47SHC (Src homology 2 domain containing) transformin... [more]
shc28.787e-1721.62SHC (Src homology 2 domain containing) transformin... [more]
ccdc1251.145e-1622.67coiled-coil domain containing 125 [Source:Xenbase;... [more]
ccdc1252.444e-1427.48coiled-coil domain containing 125 [Source:Xenbase;... [more]
ccdc1252.360e-1226.95coiled-coil domain containing 125 [Source:Xenbase;... [more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Trpm26.983e-1423.06transient receptor potential cation channel, subfa... [more]
Trpm33.459e-1321.11transient receptor potential cation channel, subfa... [more]
Trpm53.843e-1226.85transient receptor potential cation channel, subfa... [more]
Trpm53.923e-1226.85transient receptor potential cation channel, subfa... [more]
Trpm34.674e-1121.00transient receptor potential cation channel, subfa... [more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A7T1N0|TMP2L_NEMVE6.893e-1932.11Transient receptor potential cation channel subfam... [more]
sp|E9PTA2|TRPM2_RAT7.276e-1423.32Transient receptor potential cation channel subfam... [more]
sp|Q91YD4|TRPM2_MOUSE4.885e-1323.06Transient receptor potential cation channel subfam... [more]
sp|O94759|TRPM2_HUMAN5.181e-1324.06Transient receptor potential cation channel subfam... [more]
sp|Q93971|TRPG_CAEEL1.873e-1126.57Transient receptor potential channel OS=Caenorhabd... [more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T2MHH21.351e-2327.37Transient receptor potential cation channel subfam... [more]
A0A2R2MLZ32.590e-2227.03transient receptor potential cation channel subfam... [more]
A0A3Q3E8Y36.729e-2125.00Transient receptor potential cation channel subfam... [more]
A0A553PIB42.205e-2023.05Uncharacterized protein OS=Tigriopus californicus ... [more]
A0A1L3INW24.739e-2023.21Transient receptor potential cation channel subfam... [more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trpm53.165e-1125.84transient receptor potential cation channel subfam... [more]
trpm74.846e-1025.50transient receptor potential cation channel subfam... [more]
trpm75.318e-1025.50transient receptor potential cation channel subfam... [more]
trpm75.771e-1025.50transient receptor potential cation channel subfam... [more]
trpm75.785e-1025.50transient receptor potential cation channel subfam... [more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
trpm22.813e-2025.52transient receptor potential cation channel, subfa... [more]
trpm72.822e-626.37transient receptor potential cation channel, subfa... [more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO301353.176e-1931.34Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO476583.979e-1129.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hrc2.830e-1327.70transient receptor potential cation channel subfam... [more]
ENSORLT00000029710.14.488e-1227.83transient receptor potential cation channel subfam... [more]
ENSORLT00000021513.24.517e-1227.83transient receptor potential cation channel subfam... [more]
ENSORLT00000000453.23.522e-1127.32pep primary_assembly:ASM223467v1:3:5283852:5304338... [more]
trpm34.346e-1025.37transient receptor potential cation channel subfam... [more]
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BLAST of transient receptor potential cation channel subfamily M member 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000004900.10.000e+099.78SMESG000004900.1[more]
SMESG000005077.10.000e+0100.00SMESG000005077.1[more]
SMESG000005077.10.000e+0100.00SMESG000005077.1[more]
SMESG000005077.10.000e+0100.00SMESG000005077.1[more]
SMESG000017090.13.632e-7227.84SMESG000017090.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003947 ID=SMED30003947|Name=transient receptor potential cation channel subfamily M member 3|organism=Schmidtea mediterranea sexual|type=transcript|length=2632bp
GATTCACAAATTTTAAATGGCGATAAATAATGACGTCAAAATGAATTTCA
TGGAAACCAACTACGGATATTACAACAAAAATAAAGACCTATTTAAATTA
GGAATTTGTAATAAAATTCCGTATGCTATAGTTCCAGATGATATAGAGGA
GGAACGCCTGAAATGCCTCTACAATGAAGTATTACTAAAGAGATGGGAAT
TTGCCCCACCAAAGGTCGTCATTTCGATACATGGTGAAAACAAACAGTTG
AATTCAAACAAAGATCACAAAAGATTTAAACAAATGCTAATTGATATTTT
AAAACTGACAACAATGTGGATCATTACTTCGGGAAATAAAAATGGTGTTC
ATGAATTGGTTAGTGAAGCTGTTGAAGAGAATCGGCAAGATAATATTCTC
GACAAAACCATATTACTTGGAATAAAGCGTCATGTTTTCGAAGAAAATTG
TGAACTTGATATAAATGATATTTACAATGGCTATCTTCTTTACCAAACTG
AAACCAACTCTTATTATTTGGAAAATATTCAAACAAAATTTGAAAGTTTT
TTAAAAAAAACTGAAAATATTAATACTGTTCATATTATCTACGATGGAGA
CTTTGATATATTTAAACCAGTTTTCACCACACTTCATGACAAAATTCCAG
TTGTTCTAATAGAAAACAGTAAAATAGCCAATTCAATCAGCAAGATCATT
GAATTATCAGAATATAATGACGCGGAACTAAACGACATATTGAGGACGCA
TTCAAATTCTAAGGAACTGAAAACTATTAGTAATGAAATTTTTGAATTTA
AAAATTCAATAATATTATATGATATTAAAGATGAAAAAATCAATTTAAAT
AGAAAGATTTTAGAAGCACTCATATCAAATACAAAAAATACGCAGGCATC
AGATGAAGGTTTTTGTAGAAGATTGGGAAACTCTTCTAAAATGCAAGAAT
CTATTATTTATGAATGGGAATGTTTTGAATTATCTTGCATTTTCGATGAA
AATAGTTTAAATGAAAATTCATATCTAGAAAAAACTATAACTAACGATGA
TAAAAATAAAATAGAAGTCATGCTATTTACTGTTCTGAAAAATAATAAAG
CAAAGGCTCTGGAATGGCTTATGAAAATAATAAATACTACTGATGATTAC
GTTGATGAAAGTTTTCTTACACGATTATATCACGATTCAGTAACCGGCAA
TGTCAGTTGCGTGAAGGAGCTTCGGAAAAGATATGATAATTTGTCTGGCC
TAAAGTCGCAAACTAATAGTTTTTGTTGTAAACGAAAGCAGCAAAGTGCA
GGAATACCTGAAAATGAATCATTTGTGGGAACTAGTGAAGCAAATAATAA
AAAATACATATACATAGAAGAGTTATTCATTTGGGCACTACTATCCGGCT
ATACAGAAGTAGCGTTTGTATTGTGGAAATTTTGCAGTGATTTAATTGGA
ACGGCTTTAAAAGGAGCTATTAATTTAAAAAAAGTCGAAAACGATTACAA
AAATAAAAACTTGGATTGTTCAGCAGAAAAAATTTTCAAAGAATCAAAAA
AGTATGAGATGTTGGCATATAAAATCATTGAAACCGCTTATGACAAAAGT
CCAATCAGAGCTATTGAGTTAATTAATCGGCCCCTAGCCAGATGGGGTAA
TAAGAGCTGCCTTCAAATATCAGTTAATGAAGACCTCAAAGAATTTTGTA
GCAAGAGTGCTTGTGAGCATTATGCACGTTTGGCTTGGTGGGATAAAGAA
CTTCCAAATAATCGAGGGGAAAAAAAAGAAAAAGCAATTGAAAGCTCGAA
AGAAAAGTTTAAGCGAATTTTTTTTTCACCGACTTCAAAATATTGGCTGT
ATTGGATTTCTTACTTTATTTTCATCGTACAATTCATTTATGTCAATTCA
GTACTTTTGAAACCGATTTCTCTAGTAAAATTAAAATTGGAGTTGGGCGC
TGAAATTTTTGTTTTTTTATATGTATTCGGACTTCTAGTCGAAGAAATAA
AGCAGATTGCAAATAAAGAAGGCAAAACTTTGTATTCAAGATTCCAAAAG
CATTGGAGAATATGTTGGAATATATTTGATATTCTAATCATTCCATTATT
CTTTCTGTCTATGATATGCAGATTTTCTATTCACGAAGATTATTTTGTCA
TAAGCCGTTGTTTAAATGCAGTTACGTTGAGTTTATTCATATTGAGATCT
TTGCAGTTTTTCGAAATTTTTCAAAAATTTGGTACGAAAATAATAATGAT
TAAAAAAATGTTGATGGAATTATTCATTTTCTTATGTTTATTTTTTCTTT
TTATTTTGGCTTATGGAACACTATTTCAGTCGATAAAAAATCCTAACAGA
AAATGGGATATCTCTTTGCTAGTAGACATTTTCCTCTATCCTTATTTTCA
GATGTACGGAGAGTTGAAAATTGATAAATTTGAAAGTGAGTTTTATGCAA
CCATACATAAAGAATTGTCTCTAATTGCGTCAAACGTCTTAAATAACTTA
AAAGATCTAACATAAACCCCATTCATTGGTTTATGAGAATTTTGTATGAG
AAGAGGTCAGGGATGCCAGATTTTCTAAAAATCATATCGAGAAATTCCCG
ACGAAATCGGGAGTTCTGGCAAGCCTGTCGGG
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protein sequence of SMED30003947-orf-1

>SMED30003947-orf-1 ID=SMED30003947-orf-1|Name=SMED30003947-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=833bp
MAINNDVKMNFMETNYGYYNKNKDLFKLGICNKIPYAIVPDDIEEERLKC
LYNEVLLKRWEFAPPKVVISIHGENKQLNSNKDHKRFKQMLIDILKLTTM
WIITSGNKNGVHELVSEAVEENRQDNILDKTILLGIKRHVFEENCELDIN
DIYNGYLLYQTETNSYYLENIQTKFESFLKKTENINTVHIIYDGDFDIFK
PVFTTLHDKIPVVLIENSKIANSISKIIELSEYNDAELNDILRTHSNSKE
LKTISNEIFEFKNSIILYDIKDEKINLNRKILEALISNTKNTQASDEGFC
RRLGNSSKMQESIIYEWECFELSCIFDENSLNENSYLEKTITNDDKNKIE
VMLFTVLKNNKAKALEWLMKIINTTDDYVDESFLTRLYHDSVTGNVSCVK
ELRKRYDNLSGLKSQTNSFCCKRKQQSAGIPENESFVGTSEANNKKYIYI
EELFIWALLSGYTEVAFVLWKFCSDLIGTALKGAINLKKVENDYKNKNLD
CSAEKIFKESKKYEMLAYKIIETAYDKSPIRAIELINRPLARWGNKSCLQ
ISVNEDLKEFCSKSACEHYARLAWWDKELPNNRGEKKEKAIESSKEKFKR
IFFSPTSKYWLYWISYFIFIVQFIYVNSVLLKPISLVKLKLELGAEIFVF
LYVFGLLVEEIKQIANKEGKTLYSRFQKHWRICWNIFDILIIPLFFLSMI
CRFSIHEDYFVISRCLNAVTLSLFILRSLQFFEIFQKFGTKIIMIKKMLM
ELFIFLCLFFLFILAYGTLFQSIKNPNRKWDISLLVDIFLYPYFQMYGEL
KIDKFESEFYATIHKELSLIASNVLNNLKDLT*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0002142parenchyma
Vocabulary: molecular function
TermDefinition
GO:0005216ion channel activity
Vocabulary: biological process
TermDefinition
GO:0006811ion transport
GO:0034220ion transmembrane transport
GO:0055085transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePANTHERPTHR13800TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6coord: 88..455
NoneNo IPR availableTMHMMTMhelixcoord: 258..280
NoneNo IPR availableTMHMMTMhelixcoord: 290..307
NoneNo IPR availableTMHMMTMhelixcoord: 397..419
NoneNo IPR availableTMHMMTMhelixcoord: 328..350