AAA domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30003935 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of AAA domain-containing protein vs. Ensembl Human
Match: NWD2 (NACHT and WD repeat domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29229]) HSP 1 Score: 146.362 bits (368), Expect = 2.557e-34 Identity = 215/995 (21.61%), Postives = 411/995 (41.31%), Query Frame = 1
Query: 40 TSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCV--------EPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSP-VIFNREIIDIKNFI----------VISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKF---GCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHD----SECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSF-----QQQSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVLVPEFTQTEF--------NIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWY----KRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDV-IKDGYLLV--DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW--------------------------VDQTISF----HFDLKNPEMSY--NCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGKEIVLLEESINNSALVIENDL----DSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
T+LP + +P + F+ ++ ED ER+ L ++PKL+E C + +G+E ++ID+ G++ + Q+ + L C + LLG+KYGN+ P + F+++L+ K +E LE++Y D N V + EM+ + A+ P ++ ++ W++ + +F+ K+ G + + + E F + K + V + R+I +I+ F+ + + + + A EKLI + +V + +L+ + Y I G+ + ++ ID +A I + N D L YD I +A F C +IV+ + N P+I+YG P +GK+++ A + L D S+ I RF+ + ++ ++ L + E + N + + + P+ I + F + + +II E+ SE + +P LP+ +++++S+ + ++ E E + ++ QL + +T Q + +++N L T + V+ + + + S +++ +L ++ + + K+ G+ L+S L YI + GL++ E+ +VL LD VM+E+ N S + ++ P +K+ LS L++ +K+ LLV + + + L ++ L++ H ILA YF G W +++ F FD + P+ + C P ++ F N+RK +L+ HL D+L+ +I +F +LY K + ++L D +LA N +E L + + N+ I+N + SL+ EL +LLP VS P LR L+ CDK PK+ + VP++ S + SP
Sbjct: 28 TALP--SHLVPAGRSVRVFISANPEDTGAERQALRENVYPKLREFCRENYGLEFQVIDLYWGVEEDEWDSPELQKTRMKLLENCLKTSAGPCFVGLLGEKYGNIRIPGEVEASEFEMILDAAIEAK----LETKLLEEWYCRDENSVPAAYYLRPKSEMLRSNRNAMQPSTNAEN-------EKTWQEISDEIKKIFKAAVKLLHEKGKMKHSQAKRYLFSAIEDEFDFALGKQTPAFLKKCVCYIRKIANIERFVKIPEMGKYMDITGTEPRIIRDPEAQEKLIKLRDEFIPTIVASSNLRVYTSVTHCDMKLGYSQEIENHYI-----EGLGKQFYEDMIDIIQATI-------------QQNFDTETDTL--YDEILQHSSLCKTYASFYEYKCESLNIVHNYILPSKAGHIN-PLIIYGGPCTGKTLLLAEVAKKAYGWLHEDTGPESDPVVIVRFLGTT-DMSSDLRTLLLSVC---------EQLAVNYRCLVQSYPKKIHDLCDLFINLLNESSLQRPLVIIFDALEQLSE-NDDARKLWWLPAHLPRFVRIVLSTLPNKHGILQKLRCLIHEEDNYIELIPRDRKMCSQVLKHQLLRVKRKVTSGQ-QIYVNNALSKC----TLPMFVNLTFREVRHWRSHKDVDESSLSVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMSELKENTRPS-----NPLRVPYLYIARLKEGLSGYLIERHVKNVTLLVWANRHLQLIAQKLYLQDDNDLREMHTILADYFLGVWSGGRRKAFCLEDPYLNGCLDLENRSLLEEEKHFMEQASFDRQAPDQPWVFQCNPLEPDIF-------FVNHRKMSELLYHLTRCGKTDDLLYGIIMNFSWLYTMIKIGQFDKVLSDIELAYNYSQEKEL--KFLANTLRSIKNKVTAFPGSLSAELQQRLLPVVSSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSP 958
BLAST of AAA domain-containing protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 90.5077 bits (223), Expect = 2.429e-17 Identity = 89/376 (23.67%), Postives = 169/376 (44.95%), Query Frame = 1
Query: 1876 IPCQTLGEFYALNL-NRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDD--KNSHLKDFHQILAGYFNGAWVDQT---ISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIE---NDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAP-----KHNAFVPIYPSNKLPGSPLASTIN-CPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEV 2952
+P T E L R + G+ L++H L YI S GL++ E+ +VL+LD +V+ +VY + + + +++FP LW+ ++++L L DG+ L+ +A VE + + S H +LA +F+G W T I+ K + P Q ++ + N RK ++L HL+ +EL + V+ ++ + + + +LLDDF L E+ L+ E++ +E + L EL+ +L + + +P L + + C + H VP+ + PG PL +T++ C + I ++ + ++LL+ D +D+ + + +GEV
Sbjct: 553 VPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYRDWTPP---SKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLITLPLVGKPLNLDRKVAP--QPLWFS---HTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCAPHLDSPEVGLVREALQLCRPAVELRGMERSLLYTELLARLHFFATSHPAL--VGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAM-----AWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTGHTGEV 913 HSP 2 Score: 67.3958 bits (163), Expect = 2.577e-10 Identity = 82/398 (20.60%), Postives = 161/398 (40.45%), Query Frame = 1
Query: 148 RIFPKLQEQCF-DEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYN-CPIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILW-RDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKC-YDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDT--NVPIILYGPPNSGKSIVFARTIFEFQSSLPHDS 1317
R P L+ Q F G+ +++D++ G+ + T ++ E +++ C K + P F L+G +YG P IP++I + E L++H + + +Y+ D N P +L Q + C+ E S+L + Q ++ G + E + E ++ S D + +F REI D+ I+ +D +++L AD ++ D Q++L + +++ R+ W RD H Y+ + + V R ++ LD + L Y I + Q ++ + CG ++++ + L DD+ + P++L+GPP GK+ + + + L H +
Sbjct: 8 RALPTLKCQTFCQRHGLMFEVVDLRWGIRNIEATDHLTTELCLEEVDR---CWKTSIGPAFVALIGDQYG----PCLIPSRIDEKEWEVLRDHLTARPSDLELVARYFQRDENAFPPTYVL------------QAPGTGEACEPEEATLTSVLRSGAQEARRL----GLITQEQWQHYHRSVIEWEIERSLLSSEDREQGATVFLREIQDLHKHIL------EDCALRMVDRL--------ADGCLDADAQNLLSSLKSHITDMHPGVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRE--LDTAGQELAWLYQEIRHHLWQSSEVIQTFCGRQELLARLGQQLRHDDSKQHTPLVLFGPPGIGKTALMCKLAEQMPRLLGHKT 366
BLAST of AAA domain-containing protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 90.5077 bits (223), Expect = 2.629e-17 Identity = 89/376 (23.67%), Postives = 168/376 (44.68%), Query Frame = 1
Query: 1876 IPCQTLGEFYALNL-NRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDD--KNSHLKDFHQILAGYFNGAWVDQT---ISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIE---NDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAP-----KHNAFVPIYPSNKLPGSPLASTI-NCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEV 2952
+P T E L R + G+ L++H L YI S GL++ E+ +VL+LD +V+ +VY + + + +++FP LW+ ++++L L DG+ L+ +A VE + + S H +LA +F+G W T I+ K + P Q ++ + N RK ++L HL+ +EL + V+ ++ + + + +LLDDF L E+ L+ E++ +E + L EL+ +L + + +P L + + C + H VP+ + PG PL +T+ C + I ++ + ++LL+ D +D+ + + +GEV
Sbjct: 553 VPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYRDWTPP---SKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLITLPLVGKPLNLDRKVAP--QPLWFS---HTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCAPHLDSPEVGLVREALQLCRPAVELRGMERSLLYTELLARLHFFATSHPAL--VGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAM-----AWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTGHTGEV 913 HSP 2 Score: 67.3958 bits (163), Expect = 2.883e-10 Identity = 82/398 (20.60%), Postives = 161/398 (40.45%), Query Frame = 1
Query: 148 RIFPKLQEQCF-DEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYN-CPIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILW-RDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKC-YDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDT--NVPIILYGPPNSGKSIVFARTIFEFQSSLPHDS 1317
R P L+ Q F G+ +++D++ G+ + T ++ E +++ C K + P F L+G +YG P IP++I + E L++H + + +Y+ D N P +L Q + C+ E S+L + Q ++ G + E + E ++ S D + +F REI D+ I+ +D +++L AD ++ D Q++L + +++ R+ W RD H Y+ + + V R ++ LD + L Y I + Q ++ + CG ++++ + L DD+ + P++L+GPP GK+ + + + L H +
Sbjct: 8 RALPTLKCQTFCQRHGLMFEVVDLRWGIRNIEATDHLTTELCLEEVDR---CWKTSIGPAFVALIGDQYG----PCLIPSRIDEKEWEVLRDHLTARPSDLELVARYFQRDENAFPPTYVL------------QAPGTGEACEPEEATLTSVLRSGAQEARRL----GLITQEQWQHYHRSVIEWEIERSLLSSEDREQGATVFLREIQDLHKHIL------EDCALRMVDRL--------ADGCLDADAQNLLSSLKSHITDMHPGVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRE--LDTAGQELAWLYQEIRHHLWQSSEVIQTFCGRQELLARLGQQLRHDDSKQHTPLVLFGPPGIGKTALMCKLAEQMPRLLGHKT 366
BLAST of AAA domain-containing protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 90.5077 bits (223), Expect = 2.629e-17 Identity = 89/376 (23.67%), Postives = 168/376 (44.68%), Query Frame = 1
Query: 1876 IPCQTLGEFYALNL-NRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDD--KNSHLKDFHQILAGYFNGAWVDQT---ISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIE---NDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAP-----KHNAFVPIYPSNKLPGSPLASTI-NCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEV 2952
+P T E L R + G+ L++H L YI S GL++ E+ +VL+LD +V+ +VY + + + +++FP LW+ ++++L L DG+ L+ +A VE + + S H +LA +F+G W T I+ K + P Q ++ + N RK ++L HL+ +EL + V+ ++ + + + +LLDDF L E+ L+ E++ +E + L EL+ +L + + +P L + + C + H VP+ + PG PL +T+ C + I ++ + ++LL+ D +D+ + + +GEV
Sbjct: 553 VPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYRDWTPP---SKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLITLPLVGKPLNLDRKVAP--QPLWFS---HTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCAPHLDSPEVGLVREALQLCRPAVELRGMERSLLYTELLARLHFFATSHPAL--VGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAM-----AWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTGHTGEV 913 HSP 2 Score: 67.3958 bits (163), Expect = 2.883e-10 Identity = 82/398 (20.60%), Postives = 161/398 (40.45%), Query Frame = 1
Query: 148 RIFPKLQEQCF-DEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYN-CPIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILW-RDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKC-YDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDT--NVPIILYGPPNSGKSIVFARTIFEFQSSLPHDS 1317
R P L+ Q F G+ +++D++ G+ + T ++ E +++ C K + P F L+G +YG P IP++I + E L++H + + +Y+ D N P +L Q + C+ E S+L + Q ++ G + E + E ++ S D + +F REI D+ I+ +D +++L AD ++ D Q++L + +++ R+ W RD H Y+ + + V R ++ LD + L Y I + Q ++ + CG ++++ + L DD+ + P++L+GPP GK+ + + + L H +
Sbjct: 8 RALPTLKCQTFCQRHGLMFEVVDLRWGIRNIEATDHLTTELCLEEVDR---CWKTSIGPAFVALIGDQYG----PCLIPSRIDEKEWEVLRDHLTARPSDLELVARYFQRDENAFPPTYVL------------QAPGTGEACEPEEATLTSVLRSGAQEARRL----GLITQEQWQHYHRSVIEWEIERSLLSSEDREQGATVFLREIQDLHKHIL------EDCALRMVDRL--------ADGCLDADAQNLLSSLKSHITDMHPGVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRE--LDTAGQELAWLYQEIRHHLWQSSEVIQTFCGRQELLARLGQQLRHDDSKQHTPLVLFGPPGIGKTALMCKLAEQMPRLLGHKT 366
BLAST of AAA domain-containing protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 90.5077 bits (223), Expect = 2.629e-17 Identity = 89/376 (23.67%), Postives = 168/376 (44.68%), Query Frame = 1
Query: 1876 IPCQTLGEFYALNL-NRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDD--KNSHLKDFHQILAGYFNGAWVDQT---ISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIE---NDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAP-----KHNAFVPIYPSNKLPGSPLASTI-NCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEV 2952
+P T E L R + G+ L++H L YI S GL++ E+ +VL+LD +V+ +VY + + + +++FP LW+ ++++L L DG+ L+ +A VE + + S H +LA +F+G W T I+ K + P Q ++ + N RK ++L HL+ +EL + V+ ++ + + + +LLDDF L E+ L+ E++ +E + L EL+ +L + + +P L + + C + H VP+ + PG PL +T+ C + I ++ + ++LL+ D +D+ + + +GEV
Sbjct: 553 VPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYRDWTPP---SKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLITLPLVGKPLNLDRKVAP--QPLWFS---HTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCAPHLDSPEVGLVREALQLCRPAVELRGMERSLLYTELLARLHFFATSHPAL--VGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAM-----AWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTGHTGEV 913 HSP 2 Score: 67.3958 bits (163), Expect = 2.883e-10 Identity = 82/398 (20.60%), Postives = 161/398 (40.45%), Query Frame = 1
Query: 148 RIFPKLQEQCF-DEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYN-CPIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILW-RDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKC-YDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDT--NVPIILYGPPNSGKSIVFARTIFEFQSSLPHDS 1317
R P L+ Q F G+ +++D++ G+ + T ++ E +++ C K + P F L+G +YG P IP++I + E L++H + + +Y+ D N P +L Q + C+ E S+L + Q ++ G + E + E ++ S D + +F REI D+ I+ +D +++L AD ++ D Q++L + +++ R+ W RD H Y+ + + V R ++ LD + L Y I + Q ++ + CG ++++ + L DD+ + P++L+GPP GK+ + + + L H +
Sbjct: 8 RALPTLKCQTFCQRHGLMFEVVDLRWGIRNIEATDHLTTELCLEEVDR---CWKTSIGPAFVALIGDQYG----PCLIPSRIDEKEWEVLRDHLTARPSDLELVARYFQRDENAFPPTYVL------------QAPGTGEACEPEEATLTSVLRSGAQEARRL----GLITQEQWQHYHRSVIEWEIERSLLSSEDREQGATVFLREIQDLHKHIL------EDCALRMVDRL--------ADGCLDADAQNLLSSLKSHITDMHPGVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRE--LDTAGQELAWLYQEIRHHLWQSSEVIQTFCGRQELLARLGQQLRHDDSKQHTPLVLFGPPGIGKTALMCKLAEQMPRLLGHKT 366
BLAST of AAA domain-containing protein vs. Ensembl Celegans
Match: T05C3.2 (pep chromosome:WBcel235:V:5493747:5503010:1 gene:WBGene00020254.1 transcript:T05C3.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T05C3.2) HSP 1 Score: 200.29 bits (508), Expect = 3.226e-51 Identity = 218/944 (23.09%), Postives = 403/944 (42.69%), Query Frame = 1
Query: 124 IERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGL-DSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIY--------PDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFR--ILWRDDTGVSEAHHQIYIDQF----EAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSN---CTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSN-----KKFIIILHDFEKCSEV-GSQSLVTDLIPKFLPKNLKLIVSSTDS-----------FDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNS----MEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLA----TTVSVESLIDDKNSHLKDFHQILAGYFNGAWVDQTISFHFD---------LKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNG------GKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSPL 2781
+ER L I+PKL+E C + +G++ +++D++ G+ D + + E N + N +FL QKYG P IP++I LE LK + + + L+ +Y+ D N V P +L I +I P L +QD ++W + ++ + L + ++ C G LD E + F++ E I K + + + R I N I +S K K +D+ ++ +N + Q +L + A + R + W G+ +H YI QF IT+ V + + A+ + + I +++ + + C + ++ ++ +PIIL G GK+ + A+ + + + E + RF+ ++ IA + S+ QI++ ++ LKNS P ++ + F++ +N K +II + S + G+ L+ P LP +KL S T + ++ Y ++VP + ++ L++ G+ L+E Q N + T + V Y + S E I +L E + +R + GK L+SH L YI + G++D EV ++++LD KV+++++ H + + P LW I+ +L L + DG ++++ V++E + N HL+ H +A YF G W + + +N ++ PK +++ K GN YN RK +L HL+ DEL+ +FD+++L+ K + + L+ D++ A +++ L +++ SA ++ + LA EL+ +LLP V+ + L+ CDK P+HN+FVP + PG PL
Sbjct: 114 VERNALMEEIYPKLKEYCRETYGLDFQVVDMRWGVRDESTDDHMTTKLCLSEIANCQRLSVGANFVVFLC-QKYG--YRP--IPSEILSTELEMLKRTLREEHEDISLLDNWYIEDSNSVPPMFVLQQISSILVNFNNKRIPKLQEQD-------AKQWWECEAKMQQLLRKGARSCYEKGFLDREAMHNYFMSVTEREVVHGILKVKNPNEHCLCYIRHI----NNIALSQMK-------TASKFVDIAHNH-----VNSEAQKLLANLRDERVPAKLAMQNIRRSTVEWVGRDGIDVQYHAEYIRQFCTDFYKSITSMVDNAMEKHARFRDQLFTEVLTHLTTGITVSNMFFGRNEQLDCAKQYVL---------GNSTLPIILQGENGCGKTSLMAKIATKIREWYDNSCEPVVLLRFLGTSPDSSNIAPLLTSVCDQIAS------NYDESLKNSS------PTELSKLFQHFKKITNLATREKPLVIIFDSLDLLSRIDGAHELL--WFPPSLPPFVKLFASLTPGGSLIYSKMQRLIEDKRQY---LMVPSLGKDLGFQVVREWLSDKGRTLSERQ-----WNTVSKALDKCTLPLFVKLIYATVARWKSYSRPQETILFSSLQESINVLFHRTESQHGKLLVSHALSYISAARSGISDSEVEDLISLDDKVLDDIFQYHLPP------VRRIPPLLWSRIRSDLPGYLSERAADGVIVLNWYHQQFRQVAIERYFKNVN-HLETCHSAMAEYFLGVWGGVPKPYQYTEMQKQRFGVTENEGLADRKVPKQPNVFSSKDGNHRYNTRKLNELPYHLLRSGRVDELLTLCLFDYEFLHAKVSSFPLQSLIADYEDAIQNVRDVEISRQLSLAVDALRLSASILSRNPSMLAFELLGRLLPLVATNKYVSKLLIKCDKEGPQHNSFVPAHHCFHAPGGPL 991
BLAST of AAA domain-containing protein vs. Ensembl Celegans
Match: qui-1 (QUInine non-avoider [Source:UniProtKB/TrEMBL;Acc:N1NTL8]) HSP 1 Score: 53.9138 bits (128), Expect = 1.391e-6 Identity = 95/435 (21.84%), Postives = 175/435 (40.23%), Query Frame = 1
Query: 1423 FETILKNSKEIENNIPRDI------EGILLSFQ---QQSNKKFIIILHDFEKC------SEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLN--VLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLID---DKNSHLKDFHQILAGYFNGAWVDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNG--GKEIVLLEESINNSALV-IENDLDSLAGELIMQL 2658
+ TI N I N P+++ GIL S + Q+++K I + D S++G ++ + P NL L ++S++ + + V V ++ E +Q K LT EQ + + DGIL A + ++N + G + R K FGK + + + +I SS GLT E+ + ++ D++V+ E+ ++ SL+ I+ + L IL VI D ++ +A + + L + + ++ H L+ F +D S ++ S K N N+R+ R L H + N D L + + F+Y+ T+ +S LL ++ ++ ++ E + ALV + D + LA E+I +L
Sbjct: 151 WRTICLNICSISNIDPKEVLEHFKLGGILKSLEELVQKADKPVCIFIDDVHLLKFGHLLSQIGRRT-------ETAPDNLSLFMTSSNVAPVNAVFAVTQTVNVDVISENEVVGMVQKMAEKVDKKLTNEQISA-IRPLMAAKDGILIAKS-----FTHEILFNGNSSMKGGMDGR-----MTRIEKEFGKLAVGNAVKFIAASSHGLTRLEIHDAISADREVLEEMNMSIVYSLLTLDGII-----------EALGPILRKVIIDDRQIIGIAHSGLISWLRNRYLTSSQDIRSAHLQLSDLFADLLIDNEQSPRHEIAYQSFSQGI----------KRDNGSPNFRRLRLLWYHCLHSGNLDRLKELSLCHFEYVDYVTRYFGISHLLSLYEECATQILHHDLQVISEQVLVPALVTMARDSEQLAAEVIGRL 546
BLAST of AAA domain-containing protein vs. Ensembl Celegans
Match: qui-1 (QUInine non-avoider [Source:UniProtKB/TrEMBL;Acc:N1NTL8]) HSP 1 Score: 53.5286 bits (127), Expect = 1.993e-6 Identity = 95/435 (21.84%), Postives = 175/435 (40.23%), Query Frame = 1
Query: 1423 FETILKNSKEIENNIPRDI------EGILLSFQ---QQSNKKFIIILHDFEKC------SEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLN--VLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLID---DKNSHLKDFHQILAGYFNGAWVDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNG--GKEIVLLEESINNSALV-IENDLDSLAGELIMQL 2658
+ TI N I N P+++ GIL S + Q+++K I + D S++G ++ + P NL L ++S++ + + V V ++ E +Q K LT EQ + + DGIL A + ++N + G + R K FGK + + + +I SS GLT E+ + ++ D++V+ E+ ++ SL+ I+ + L IL VI D ++ +A + + L + + ++ H L+ F +D S ++ S K N N+R+ R L H + N D L + + F+Y+ T+ +S LL ++ ++ ++ E + ALV + D + LA E+I +L
Sbjct: 416 WRTICLNICSISNIDPKEVLEHFKLGGILKSLEELVQKADKPVCIFIDDVHLLKFGHLLSQIGRRT-------ETAPDNLSLFMTSSNVAPVNAVFAVTQTVNVDVISENEVVGMVQKMAEKVDKKLTNEQISA-IRPLMAAKDGILIAKS-----FTHEILFNGNSSMKGGMDGR-----MTRIEKEFGKLAVGNAVKFIAASSHGLTRLEIHDAISADREVLEEMNMSIVYSLLTLDGII-----------EALGPILRKVIIDDRQIIGIAHSGLISWLRNRYLTSSQDIRSAHLQLSDLFADLLIDNEQSPRHEIAYQSFSQGI----------KRDNGSPNFRRLRLLWYHCLHSGNLDRLKELSLCHFEYVDYVTRYFGISHLLSLYEECATQILHHDLQVISEQVLVPALVTMARDSEQLAAEVIGRL 811
BLAST of AAA domain-containing protein vs. Ensembl Fly
Match: CG10185 (gene:FBgn0038397 transcript:FBtr0083235) HSP 1 Score: 149.058 bits (375), Expect = 1.838e-35 Identity = 219/945 (23.17%), Postives = 399/945 (42.22%), Query Frame = 1
Query: 124 IERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGL-DSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAI--------YPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDII-----CNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTS---NCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQ-----QSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVS-STDSFDTRKPYFLNVLVPEFTQTEFNIFIQTQLN-----NTGKLLTEEQNERFLSNYLK--FTDGILTAS--VIVDYFYNQNFIYNS----MEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDDKNSHLKD------FHQILAGYFNGAW---VDQTISF------HFDLKNPEMSYNC-CPKSQKMYAKKSG-NVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLA------RNGGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSPL 2781
+ER L + +P++++ C ++ G+E +++D++ G+ D + + E N + N +FL GQKYG P I + L+ E L + V+ L+ +Y D N V P +L I +I P L +D Q W T + + L + + ++ + E V F++ E I ++K + + R I N I + N KK I + +D +++A L+ DL+ V +I + K+ + W G+ H+ Y++ F + VV+ V +K D SA +I+ CN ++I + C E I ML D++ P++L+G GK+ + ++++ + + RF+ + + + +SI QIS + FE NIP D+ + F+Q + I L ++ + + V+ IP LP + K+I+S + + + + +VL + E N T L N K+ + R L+NY + I S + V + + + S E T+ + L R K+ G+ L+ H L YI S GL++ E+ ++++LD KV+++VY H + P LW I+ +L L + DG V++ + K + K+ FH ++A Y+ G W V + F F L + E S + P +++ K G + YN RKF +L H V + +L ++V+F++D+L+ K + + +L DF+ A + +E++L+ +++ ++ + LA +L+ +LLP + PN++ L+ CD+ PK A +P+ PG PL
Sbjct: 38 MERNTLMAKCYPRIKDYCREKHGLEFQVVDMRWGVRDEATDDHMTTELCMREIKNCQRLSMGPNFIVFL-GQKYGYRPIPTYIVSSELALICEELTS----MGVDRAILDLWYKKDSNAVPPISVLQPISSILINFNNKRVPKLQAED-------QAVWWDTLNKMQKLLRKAAASLGASNKMSKEDVHNYFMSVTEREVINGILNVKNTKNHCLSYVRYI----NNINLQNLKKASLFVDIINRSLD---TESAKLL--SDLRDVRLPA-----KIEAVNAQKYTVEWIGREGLDIETHEEYLNHFISHFYKNVVKLVDRAMRK--EDSSAQGQIVTEILQHLHACNNSVKIFYGREESC--ERIKRYMLG-----DSDKPLVLFGDGGCGKTSLLSKSVSLVATEWFAHVRPINVIRFLGTTPDSSALTATLISICQQISYNYML--PFE-----------NIPDDLVPLTAHFKQLLTYASPTQPLTIYLDSVDQLTGTQDSNKVS-WIPTRLPPHCKIIISCANEPANPTVSHEYHVLC-KMIDVEENFIEVTALGEDLAMNVIKMWMKTAC-RDLNNYQWRLVANAISKCSLPIFVKLVFAEICRWRSYTRPQETHLANTVMDSIMLLFERVEKQHGRILVFHALAYITASKSGLSESELEDLISLDDKVLDDVYQYHLPP------TRRIPPLLWTRIRNDLPNYLSEREADG---VNVMNWYHRQFRDTAKERYFKNMNMAIYFHSMIADYYLGIWGGGVPKPFKFTEIQRHRFGLADKEGSADRKVPIQPLVFSSKDGLSKRYNLRKFGELPFHFVRSRRFKDLFEHVLFNYDWLHAKLSSCPLQAVLADFEDASSNTDDKEAKRELMLVSDALRLGGAILAIYPNMLAPQLVGRLLPEIGGNPNIKMLLRACDRSGPKDCALIPVNHCLHTPGGPL 922
BLAST of AAA domain-containing protein vs. Ensembl Zebrafish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 151.754 bits (382), Expect = 4.259e-36 Identity = 228/965 (23.63%), Postives = 408/965 (42.28%), Query Frame = 1
Query: 70 PERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKY-NCPIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQD------RNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVN----EFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERA---KKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIV--YAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCT-IAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVS-STDSFDTRKPYFL---NVLVPEF-TQTEFNIFIQTQLNNTGKLLTEEQNERFL------SNYLKFTDGILTASVIVDYF-YNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVD-----LATTVSVESLIDDKNSHLKDFHQILAGYFNGAWVDQTISFHFDLKNPEMS--YNCCPK--SQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIENDLD---------SLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAF-----VPIYPSNKLPGSPLASTIN 2796
P ++ F+ S+ D + ER + + +LQ C G+ +++D K G+ + TA+ I + + C + + P F L+G +YG+ L P IP F+LLL L + L Q++ D N + P IL+ I YP ++D R++ +I W T+S L + ++ + +G + K F + E E F T R + S V+F RE+ + K D +K+ + L+DVT D E L + ++ N+ +P L + S H+ Y+ + +T+++ E ++ A ++D S+LK +I +A L K A F G +DI+ ++ + ++D ++ P++++GPP GK+ + + E ++ + + + + + + + LQ+ + + + I + R +L +Q + ++IL E+ E + D IPK +P N++++ S S + D K N+ E T+ + I ++ + LT EQ + L N L + TA + Y + + S EE+ Q + +L +N GK L+SH L +I S GL++ E+ +VL+LD V+ E+Y L ++++FP W ++ +LS L + + G LL+ A V L D + D H ILA YF+G W + + P +S N K Q ++ + N RK +L HL +DEL ++V+ D+L KT VS ++ D L + EI LL+E+ L+++ LD L E+ +L +YP++ + + C + ++ VP + PG PL ST+
Sbjct: 25 PTSRMVRVFISSTHSDMKNERNAFWEKTYSELQTHC-QSLGLVFEVVDFKCGMR---DITASDHLITELCIKEIETCQRISDGPTFIALIGNQYGHRLVPRLIPEAEFELLLSKLSKDPESL----KLLNQWFYKDSNSIPPTYILLPITVHYPHYNERDSENAQLRDNDVI---SWNLTESRLLQVLRSAALQAERDGDFTADSKHKFFKSVLEYEMEHGFLRTQRDA-----SAVLFFRELPRLS---------KRDCKKNFAKFLLDVTADGLLDTQARELLTDLKQRICNTGR-----LQPLCMELSKGAMDPSRKEHKEYLGKLCEQVTSQLKELISRNALQTSGTSVDPVWSWLK-QEIFHHAKLSEEKCAVFK-GRDDILGKISITLWESNDVSHGPLLVHGPPGVGKTALLCKLAKEMRAVVDNRGVVLLRLLGTSLLSSDVDSVLRGVCLQVCGALGLQSPYSHIAYT----HEGLVRFFHSMLEDVSKQGDT-LLLILDSLEQLLETNKLHKL-DWIPKIIPPNVQIVFSTSNECLDKCKSLVSAEENIFKLELLTKDQGRDVIDAYMSAAERKLTAEQQDAILRYFEQSGNPLHLKLMLDTAKLWSSYTPMSSVHLDKSAEEVMTQFV---ESLEVNH-----GKKLVSHALSFILLSRYGLSEAELQDVLSLDNDVLAEIY---KCWLPPSHTLMRFPRFHWSRLRHDLSAHLTERWEAGVLLLGFTHRQFAELVRRRYLSRDVKA---DMHTILAEYFSGQWSKGQLR---PILLPSLSAFLNADRKVSPQPLWFSEE---LANLRKIHELPYHLAHAGKWDELRQSVLGSLDWLCCKTLQCGVSCVIQDLTLCTDLTDCPEIQLLKETF----LLLKPSLDFSDGRVDPSLLVTEIFARLQGLADHYPSM--IGQLCSQCMDWFESYSDPLLVPKCSFFEAPGGPLKSTLR 925
BLAST of AAA domain-containing protein vs. Ensembl Zebrafish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-161213-1]) HSP 1 Score: 90.1225 bits (222), Expect = 2.238e-17 Identity = 91/367 (24.80%), Postives = 157/367 (42.78%), Query Frame = 1
Query: 1813 TASVIVDYFYNQNFIYNSMEEIP----CQTLGE-----FYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATT---VSVESLIDDKNSHLKDFHQILAGYFNGAWVD-QTISFHFD-----------LKNPE-----MSYNCCPKSQKMYAKKSGN--------------VFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
T + V+ Y + + S +++ C T+ E FY++ + G + L YI + GLT+ E+ ++L+LD V+ ++ + S +L +S ++ +K+EL LV+ L+ A + + L + H +LA YF GAW + FH D +NP ++ + Y +++ F N+RK +L HL D+L+ VI +F +LY K + + L D LA + KE+ L ++ + L + + SL+ EL +LLP V+ P LR L+ CDK PK+ + VP++ S + SP
Sbjct: 610 TLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVE-----NKLGSRFVFRALGYITMARAGLTELELEDILSLDNSVLGDIMV--SSNL---KSPLRISYDFIARLKEELEGYLVERQVHNVTLMVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFHCDNNHFASLNISQHRNPHNQQSLHGHDKASADKHSYDRQTPEQPWVFQCNLLEPDIFFVNHRKMTELTYHLTRSGRTDDLMYGVIMNFSWLYTMIKIGQFDKALSDIDLAYSYTQEKELKFLATTLRSIKLKVTKNPASLSAELQQRLLPVVTSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSP 966 HSP 2 Score: 71.2478 bits (173), Expect = 1.357e-11 Identity = 39/144 (27.08%), Postives = 74/144 (51.39%), Query Frame = 1
Query: 67 LPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNF----LEQYYVLDVNCVEP 486
+P + F+C++ +D E ER L ++PKL++ C + +GIE +++D+ G+D + Q++ + L + C + L+G+KYG++ P + + F+++L+ AVE LE++Y D N V P
Sbjct: 35 VPTGRSVRVFICANPDDTEAERNALKEHVYPKLRDFCRENYGIEFQVVDLYWGIDPEEWDSPELQRLRMKLLEECLKTSAGPCFVGLIGEKYGSIRVPGEVESAEFEMILDA--------AVEAGLDTRILEEWYCRDENSVPP 170
BLAST of AAA domain-containing protein vs. Ensembl Zebrafish
Match: CU570791.3 (NACHT and WD repeat domain-containing protein 2-like [Source:NCBI gene;Acc:108179119]) HSP 1 Score: 63.5438 bits (153), Expect = 3.164e-9 Identity = 47/204 (23.04%), Postives = 90/204 (44.12%), Query Frame = 1
Query: 85 INFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIF---LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFE 687
+ ++CS+ ED +ER ++ ++FP+L+E C +G++ ++I D Y T E L C + F L+G++YG+ P ++ F+L+L+ +R + + LE+ Y D N + P +++ Q N ++ W K + + ++ C+ GTL +E K F + E
Sbjct: 4 VQVYLCSNPEDSVVERTLIRQKVFPRLREYCRSTYGLDFRVI------DPYEATKPKNWPTQQERLRILEDCWNNSLHSFFVGLVGEQYGDACLPEQVEASEFQLILQVC----QRMGFKTDVLEKCYRRDENTIPPSFCMLEPSRRCKQTSVQQENPTE--EKNWCKVFPEVRRILHDVVNQCIQEGTLALEKAQKYFQSSLE 195 HSP 2 Score: 60.4622 bits (145), Expect = 2.515e-8 Identity = 119/522 (22.80%), Postives = 219/522 (41.95%), Query Frame = 1
Query: 1195 DYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPH-DSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDS----FDTRKPYFLN-VLVPEFTQTE---FNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLG-EFY---ALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFP----------LSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDDKNSHLKDFHQILAGYFNGAWVDQTISFHFDLK-----------------NPEMSYNCCPKSQKMYAKKSGNVFY--NYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNG----GKEIVLLEESINNSALVIEND 2622
YL +T P IL G P SGK+++ A + L + D E + F+ N ++ ++ + I R + T + + +++ N R LL+ + S +II+ ++ + Q +T L PK L N+KL++S + + K Y+ + L E Q + N + T L + + +T Q + +++ LK T + V+ Y Q ++S EI +TL E + L + ++ GK+L+S L Y+ + G+T E+ +VL+ D +V+ E ++ E + + ++ P L +L+ + L + + + LV V + L ++ LK H +L+ YF+G+W + T HF + + ++ C SQ Y + N RK L HL+ +EL +I +YL A+ EL L + +E+ LL + +SA ++ N+
Sbjct: 336 SYLEGKNTLFPFILNGGPYSGKTVLLAHCASQVSVWLKNLDPE--ILVFFIDVNSSLRQL-------LKYICERADSSNTNINSIFQLKENFKR-----LLTVRSTSKNPLVIIIDGLDQLPKTDGQPDLTCL-PKALAPNVKLLISVSANRHALLAALKQYYPDSALFCELQQVDTKSCNQLLTTLLQGSNRKITSGQ-QVYVNEALKKC----TVPLYVELLYRQAVCWHSEFEITEETLDLEVHNSIVLIFDHMERKHGKSLVSKALSYLTLARYGMTTAELTDVLSCDDEVV-ESFLPQGEGV---PATLRVPEVSVETLLSDLKGFLVQRNILGTQTLSWVNRHFPLV-----VCKQYLCSEETC-LK-IHHVLSDYFSGSWANGT-KKHFIINKDTQIQSSSDVPRNIYIDRQVPSQPCIFSQPFYISTAMRTPTRPNLRKLHTLSFHLLKSGRIEELGSQMISQ-EYLQVMLHAMLADELF--LWLEKTSQLIFPRELQLLHAILKSSACLLRNN 822
BLAST of AAA domain-containing protein vs. Ensembl Xenopus
Match: hsp90ab1 (heat shock protein 90kDa alpha family class B member 1 [Source:Xenbase;Acc:XB-GENE-495311]) HSP 1 Score: 138.272 bits (347), Expect = 7.188e-32 Identity = 210/979 (21.45%), Postives = 390/979 (39.84%), Query Frame = 1
Query: 67 LPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYK-QDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSP-VIFNREIIDIKNFI----------VISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKI--NLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFA----RTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQS--NKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDS-----------FDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQ---NERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWY----KRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDV-IKDGYLLV--DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW--------------------------VDQTISFH----FDLKNPE--MSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGG--KEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
+P + F+ S++ E ER L ++PKL+E C + +G+E ++ID+ G+ + Q+ L + C + LLG+KYG + P + + F+++L+ K +E LE++Y D N V P L + + + D + ++ W+ + ++F K+ G L V + + E F + K + V + R+I +I+ + VI + K + A+EKL + +V + +L+ + Y + G+ + ++ ID +A + +I +L L ++ Y+ C A +NK+ + C I P+I+YG P +GK+++ A + Q + DS+ I RF+ S T L+ LQ L N + K+I N + + L+ +S ++ +IIL E+ S+ + +P LP+ +++I+S+ + Y L+P + I L K+ + +Q NE F T + V+ + + + S +++ TL N+ + + + G +S L YI ++ GL++ E+ ++L LD VM+EV N + ++ P + +K++L+ LV+ +++ LLV + + + L++ H +A YF G W +D+ ++ FD + PE ++ C P ++ F N+RK +L+ HL +EL+ + +F +LY K + L D +A N KE+ L ++ + I + SL+ EL LLP VS P R L+ CDK PK+ + VP++ S + SP
Sbjct: 35 IPTGRSVRVFIMSTYHT-EAERNELREHVYPKLREFCRENYGMEFQVIDLYWGIPEEDWDSPDLQKTRMRLLEECLKTSAGPCFVGLLGEKYGTIRIPGEVESSEFEMILDAAIEAK----LETRTLEEWYCRDENAVPPAYYLRPKSEMLKNHHNPGDSTTGSANEKTWRTVAEEIKHIFSTSVKLLQEKGKLKNNQVKRYLSSALEDEFDFALGKQTAAFLKKCVCYIRKISNIERHVKIPEMARYTDVIKVENKYIRDPEALEKLAKLRDEFIPTIVASSNLRVYTSVTHCDMKLGYSQEVENHYV-----DGLGKQFYEDMIDIIQATVQQNFETETDPLYDEILQHLSLCKTYASFYEYRCEALNLVNKYLR-PCRSGHI--------------YPLIIYGGPCTGKTLLLAEVAKKACSWLQEEMGPDSDPVVIVRFLGS--TDMSSALNCLLQSICEQLAVNYRCLLQSRPKKILN-----LHELFLNLLNESSFHRPLVIILDGVEQLSDSDDARKLW-WLPVHLPRTVRIIISTLPNKHGILQKLRCLIHNEDSYI--ELIPRDKKMCSQILKHQLLRVKRKVTSGQQIYVNEAF---------SKCTLPMFVNLTFREVRNWRSHKDVDGSTLCVTVHRNIEQLFWSLENKCGPRFVSRALGYITMATTGLSEVELEDILALDNTVMSEVLSNMKPYI-----PLRIPYIMIAQLKEDLTGYLVERQVRNVTLLVWANRHLQLVAQKFYLQNADDLQEMHSNMAEYFLGVWAGGIKKPFYNEPQYFENCIRKETRSILDENKHYNEQTSFDRQPPEQPWAFQCNPLEPDIF-------FVNHRKMTELLHHLTRSGMMEELMTGITMNFSWLYTMIKIGQFERALSDIAVAYNYSQQKELKFLASTLQSIKHKILKNPGSLSAELQQILLPVVSSLPKFRNLLVQCDKDGPKYCSIVPLHSSMDVTYSP 957
BLAST of AAA domain-containing protein vs. Ensembl Xenopus
Match: ppp1r3c.1 (protein phosphatase 1, regulatory (inhibitor) subunit 3C, gene 1 [Source:Xenbase;Acc:XB-GENE-969181]) HSP 1 Score: 101.293 bits (251), Expect = 1.286e-20 Identity = 125/571 (21.89%), Postives = 248/571 (43.43%), Query Frame = 1
Query: 1165 GYEDIVYAMLDYLTDDDTNV--PIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTS--NCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCSEV-GSQSLVTDLIPKFLPKNLKLIVSS-----------TDSFDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDD--KNSHLKDFHQILAGYFNGAWVDQT-ISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYP-NLRFLIENCDKVAP-----KHNAFVPIYPSNKLPGSPLASTIN 2796
G +D++ ++ Y+ + + V P+I++G SGK+ + + FE + S + TS + I ++ SI Q+ I L + + N I N R +L + ++ + ++ ++ S G+ L +PK P N+ ++VS+ DS + Y + V + + + I+ + + G+ LT +Q E L ++ K +L + D + E + + E +L + GK L+SH L YI S GL++ E+ ++L+LD +V+ ++Y + +++FP W ++ +L LV+ DG ++ L +E D N+ + H LA YF G W T L N ++ + SQ ++ + N RK +L HL+ DEL ++ + D++ +K + + ++ DF+++ +EI+LL +++ S L + ++ D + + ++L + ++ + R + E C + H F+P + PG PL +T+
Sbjct: 306 GRQDLLQKIMSYIQERHSQVYPPLIIHGVSGSGKTALMCKA-FEMLKQTNNGSSLMVLRLLGTSPQSSEIHDVLKSICYQL-CIALELQPPSSQITN---IYNETVRFFHQLLTTVSERKVENLVLFFDSLDQLSPSEGAHRL--HWLPKECPANVCIVVSTLPEEGGILKTLKDSVTDPECY---IEVKPLSAEQGSQMIEMLMASAGRRLTNDQQEIVLGSFRKCGQPLLL-KLAFDEAKRWSSYTPITELMIATSTKEAVSLLYQCLEQLHGKLLVSHALGYIVASRSGLSEAELKDILSLDDEVLADIYQYWAPP---SNDLIRFPTLPWTRLRNDLEGYLVERQADGSTVLGLYHRQFIEVARDTYLTNTEKSNRHGTLADYFMGKWSMGTKRPILLPLINKSLNADRKVASQPLWFSDN---MPNRRKMSELPYHLLNAGCIDELQGEILGNMDWISSKIVSCGIQSVIKDFEMSVKLISSREIMLLRDTL--STLCLPSNTDPVI--VFTEMLARMHFFQLSYRLIDELCQQCTGWLHQYPHPTFIPTCGFFQPPGGPLQTTVT 855
BLAST of AAA domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000003639.1 (uncharacterized LOC101730828 [Source:NCBI gene;Acc:101730828]) HSP 1 Score: 63.5438 bits (153), Expect = 3.655e-9 Identity = 131/551 (23.77%), Postives = 227/551 (41.20%), Query Frame = 1
Query: 1165 GYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFV--TSNCTIAEIFL-SIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGI------LLSFQQQSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIV-----SSTDSFDTRKPYFL--NV-LVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFI-YNSMEEIPCQ-TLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEV--YINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLA----TTVSVESLIDDKNSHLKDFHQILAGYFNGAWVDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGK---EIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDK-VAPKH 2730
G E + + D +T + + ++++G SGKS + A+ + D +TRF+ T + L S+ QI+ I I + D++G+ LL F + + ++ + ++ S V SL IP+ LP+++ IV S+ SF T + + NV +P E I+ + + LT Q + L V+ Y + + Y+S + Q L + Y+ L R K G+ ++ YI S G+T +E++++L+LD VM EV Y N + S+ FP +LW+ ++ ++ LV+ D +++ A V + + K L H A Y+ ++ S H +PE P M+ +N RK + HL+ + + LI +F+++YL +K A V L +D + A N + ++ LL E++ S V+ D LA +L +L IE DK VAP H
Sbjct: 2 GRESFLQELQDCITSANKQL-VVVHGESGSGKSSIIAKIATLASQWIGRD--IRVVTRFIGRTGESRNPRMLLYSLCFQIAEIY--------------NITMDFSEDLKGLINEFSTLLEFANKC-RPLMVAVDGIDELS-VHEDSL--SWIPRVLPRHVYFIVCASTESACSSFRTLQKLTMQQNVHQIPPLDSEEIRNMIEVWMERDNRRLTGRQKKVLFDACAACP---LPLYVVSSYMESCLWTSYSSESDSYLQPNLHKLYSAVLGRLEKSHGEQVMKMVASYISLSKNGVTLEELLDLLSLDLGVMQEVKQYQNITVSV--------FPEALWIKLQNDIGTHLVEQRTDNTYVINWAHALFRVVCINRYLKSKELQL-SVHSAFANYYL-----ESKSRH---NHPEKVSLMMPL---MWTGTHRKPVFNLRKILGISHHLIHSNQFPRLITECLFNYEYLLHKVWATSVVGLQEDIKAAINPERPAPDLNLLSEALQLSTKVLLRDPTQLASQLKGRL-----------HQIEMLDKPVAPGH 497
BLAST of AAA domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000022477.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV460486.1:142089:157740:1 gene:ENSXETG00000010819.1 transcript:ENSXETT00000022477.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 55.0694 bits (131), Expect = 1.505e-6 Identity = 114/549 (20.77%), Postives = 213/549 (38.80%), Query Frame = 1
Query: 1195 DYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTS---NCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDG----------ILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYK----RFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDDKNSH---LKDFHQILAGYFNGAWV------------------------DQTISFHF-DLKNPEMS--YNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIENDLDSLAGELIMQ--LLPYVSYYPNL 2688
DY+ + P++++G GK+++ A + S L + + RF+ ++ + + Q+S I R + L + E+ ++ I LS +Q I+I+ D + + D +P +PK K+IVS NV+ + F+ ++ + + L Y K T G T+ + V + + S +++ QTLGE R + ++G+ ++S L YI S G+ E++++L D V+ + + L ++I + P + I +L L D + G LV + + ++ S +++ H + +F+G W + T + H+ D + P YN P Q+ +GNV RK +L HL ++L V F Y +A ++ LL+ + A G +E+ L + + + +++ DSL E+I Q +LP V YP L
Sbjct: 346 DYIVHGKSPKPMVVFGRSGCGKTVLLASCAKKVHSWL-ETCDPILVVRFICPFREPLHLSRLLGGLCYQLSDIYQR--VIPSHLDDVAELRQCF---VDLISLSSKQ---APLILIIDDVDH--------VPIDWLPSPIPKFTKIIVSVKHQ--------QNVISDQVKSQNKGQFLFLEIKPQRRECNDNLKHCLLGCYRKITSGQQMYVNRSLETNTSPLQVHLLFKLVAEWKSHQDVDNQTLGEDTYEAAERLFHKLEIKYGREIVSRTLSYITLSQSGIGVTELVDLLTADDLVLEKFH-----ELFGTENIPRIPDWIVTGILLDLQGCLADRMSAGCKLVYWNNRMYQQVIMTRYLSSPETVQELHTAMYYFFSGRWTCGKFISKAVQKFKSLLPNRRLANNNHTPNRHYLDYQPPSQPWFYNVLPVCQRAV---TGNV----RKALELPFHLKECGKLEKLYNEVFMAFPYYKVLVQAGQLHLLLNSIEDAAGIMGKQELYFLYDMLKEVSCLLKEKPDSL--EMIFQSKMLPLVLTYPPL 855
BLAST of AAA domain-containing protein vs. Ensembl Mouse
Match: Nwd2 (NACHT and WD repeat domain containing 2 [Source:MGI Symbol;Acc:MGI:1920464]) HSP 1 Score: 155.221 bits (391), Expect = 4.271e-37 Identity = 229/1000 (22.90%), Postives = 416/1000 (41.60%), Query Frame = 1
Query: 40 TSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQE--WKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSP-VIFNREIIDIKNFIVISNQKK------DDKR----KSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKF---GCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHD----SECHFITRFV-TSNCTI--AEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPR---DIEGILLSFQQQSN--KKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDG----------ILTASVIVDYFYNQNFIYNSMEEIP----CQTLGE-----FYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDV-IKDGYLLV--DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW--------------------------VDQTISF----HFDLKNPEMSY--NCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGG--KEIVLLE---ESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
T+LP + +P + F+ ++ ED ER+ L ++PKL+E C + +G+E ++ID+ G++ + Q++ + L + C + LLG+KYGN+ P + F+++L+ K +E LE +Y D N V P + + P K +QE W++ + +F+ K+ G + + + E F + K + V + R+I +I+ F+ I K D R A EKLI + +V + +L+ + Y I G+ + ++ ID +A + + N D L YD I +A F C +I++ + N P+++YG P +GK+++ A + L D S+ I RF+ T++ +I + LS+ Q++ N + + + P+ D+ + ++ +S+ + +IIL E+ SE ++ +P LP+ +++I+S+ + K L L + + I + + K+ ++ + L K T G T + V+ + + + S +++ C T+ E F++L K+ G+ L+S L YI + GL++ E+ +VL LD VMNE+ N S + ++ P +K+ L+ L++ +K+ LLV + + + L ++S+L++ H ILA YF G W +++ F FD + P+ + C P ++ F N+RK +L+ HL D+L+ +I +F +LY K + ++L D +LA N KE+ L SI N + SL+ EL +LLP VS P LR L+ CDK PK+ + VP++ S + SP
Sbjct: 28 TALP--SHLVPAGRSVRVFISANPEDTGAERQALRETVYPKLREFCRENYGLEFQVIDLYWGIEEDEWDSPELQKMRMKLLEECLKTSAGPCFVGLLGEKYGNIRIPGEVEASEFEMILDAAVEAK----LETKLLEDWYCRDENSV-PAAYYLRPRLEVPRSNKNSTQPSASSEQERPWQEISDEIKTIFKAAVKLLHEQGKMKQSQAKRYLFSAIEDEFDFALGKQTPAFLKKCVCYIRKIANIERFVKIPEMGKYMDITGTDPRIVRDPEAQEKLIKLRDEFIPTIVASSNLRVYTSVTHCDMKLGYSQEIENHYI-----EGLGKQFYEDMIDIIQATV-------------QQNFDTETDTL--YDEILQHSSLCKTYASFYEYKCESLNILHKYILPSKTGHIN-PLVVYGGPCTGKTLLLAEVAKKAYGWLHEDTGPDSDPVVIVRFLGTTDMSIDLRTLLLSVCEQLAV-------------NYRCLVQSFPKKIHDLRDLFINLLNESSLQRPLVIILDALEQLSE-ADEARKLWWLPAHLPRFVRIILSTLPN----KHGILQKLRCLIHEEDNYIEL---IPRDRKMCSQVLKHQLLRVKRKVTSGQQIYVNNAFSKCTLPMFVNLTFREVRHWRSHKDVDESSLCVTVHESIEQLFWSLE-----KKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMNELNENTRPS-----NPLRVPYLYIARLKEGLNGYLIERHVKNVTLLVWANRHLQLIAQKLYLQEDSNLREMHTILADYFLGVWSGGRRKAFCLEDPYLNGCLDLENRSLLEEEKHFMEQASFDRQAPDQPWVFQCNPLEPDIF-------FVNHRKMSELLYHLTRCGKTDDLLYGIIMNFSWLYTMIKIGQFDKVLADIELAYNYSQEKELKFLASTLRSIRNKVIAFPG---SLSAELQQRLLPVVSSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSP 958
BLAST of AAA domain-containing protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268]) HSP 1 Score: 87.8113 bits (216), Expect = 1.307e-16 Identity = 85/357 (23.81%), Postives = 165/357 (46.22%), Query Frame = 1
Query: 1939 GKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLV-----DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW---VDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLA--RNGGKEIVLLEESINNSALVIE-NDLDS--LAGELIMQLLPYVSYYPNLRFLIENCDKV-----APKHNAFVPIYPSNKLPGSPLASTI-NCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEV 2952
G L++H L YI S GL++ E+ +VL+LD +V+ VY + + + +++FP LW+ ++++L LV DG +L+ L+ + V L + + H +LA +F+GAW + + I+ K + P Q ++ + N RK +L HL+ +EL + V+ + ++ + + + LLDDF + E+ L+ E+I +E L+ L EL+ +LL + + +P + + + C + A + VP+ + PG PL +T+ C + I ++ S+ ++LL+ D +D+ + + + + EV
Sbjct: 616 GALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYRDWTPP---SKELLRFPPLLWVRLRRDLGHCLVRRPVDGCMLLAIAHRQLSQVIQVRYLSGPERA---KRHGVLAEFFSGAWSQGIKKLITLPLVGKPLNLDRKVAP--QPLWFS---STVANLRKLTELPFHLLHAGRLEELKQEVLGNMSWISCRGISGGIEVLLDDFDMCAPHMNSPEVDLVREAIQLCGPAVELRGLEKSVLYTELLARLLFFAASHPAM--IGQLCQQAQSWFRACPYPMLVPLAGFLQPPGGPLRATLTGCHKGITAI-----AWSLEEKLLVVGTQDGAMVVWDVEEQQVVHVLMGHTAEV 954 HSP 2 Score: 74.7146 bits (182), Expect = 1.295e-12 Identity = 85/417 (20.38%), Postives = 162/417 (38.85%), Query Frame = 1
Query: 85 INFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYN-CPIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILW-RDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDD--TNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDS 1317
+ F+ S+ D + ER+ L +P++Q C G+ +++D++ G+ + T ++ E L + C K + P F LLG +YG P RI K ++ L L + + + +++ D N + P +L Q S+++ E S+L Q ++ G + E + E + S +F R++ D+ I+ DD +++L+D NA QS+L + + + W RD H Y+ Q A+ V E+ +++ L Y I + Q + K CG+++++ + L D+ T+ P++L+GPP GK+ + + + L H +
Sbjct: 31 VVIFISSTISDMDTEREALQCTAYPEVQSFC-QRHGLAFEVVDLRWGIPNTQATDYLTTELCLEELER---CQKTSIGPAFVALLGDQYGPCPVPRRIEEKEWEALRAQLTSRPRDL----ELVTRHFQRDDNTIPPTYVL------------QPSGSLVVPGPEEATLTSVLRGGAQEAWRL----GLISQEQWMCYHRSVIEWEIELGLLSSARGDQGATVFLRDVQDLNKHIL------DDCSLKMVDRLVDGCLDTNA--------QSLLSGLKGRILDAQPGALKSHHLSWSRDLVNPKNKAHARYLKQLSEQFVARTNHQVLEQLRELELA-RQELGWLYQEIRHHLWQSTESTKVFCGHQELLAQLRQQLRQDESRTHTPLVLFGPPGIGKTSLMCKLAQQVPELLGHKT 408
BLAST of AAA domain-containing protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268]) HSP 1 Score: 87.8113 bits (216), Expect = 1.341e-16 Identity = 83/341 (24.34%), Postives = 159/341 (46.63%), Query Frame = 1
Query: 1939 GKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLV-----DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW---VDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLA--RNGGKEIVLLEESINNSALVIE-NDLDS--LAGELIMQLLPYVSYYPNLRFLIENCDKV-----APKHNAFVPIYPSNKLPGSPLASTI-NCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDL 2904
G L++H L YI S GL++ E+ +VL+LD +V+ VY + + + +++FP LW+ ++++L LV DG +L+ L+ + V L + + H +LA +F+GAW + + I+ K + P Q ++ + N RK +L HL+ +EL + V+ + ++ + + + LLDDF + E+ L+ E+I +E L+ L EL+ +LL + + +P + + + C + A + VP+ + PG PL +T+ C + I ++ S+ ++LL+ D +D+
Sbjct: 575 GALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYRDWTPP---SKELLRFPPLLWVRLRRDLGHCLVRRPVDGCMLLAIAHRQLSQVIQVRYLSGPERA---KRHGVLAEFFSGAWSQGIKKLITLPLVGKPLNLDRKVAP--QPLWFS---STVANLRKLTELPFHLLHAGRLEELKQEVLGNMSWISCRGISGGIEVLLDDFDMCAPHMNSPEVDLVREAIQLCGPAVELRGLEKSVLYTELLARLLFFAASHPAM--IGQLCQQAQSWFRACPYPMLVPLAGFLQPPGGPLRATLTGCHKGITAI-----AWSLEEKLLVVGTQDGAMVVWDV 897 HSP 2 Score: 67.3958 bits (163), Expect = 1.969e-10 Identity = 82/406 (20.20%), Postives = 156/406 (38.42%), Query Frame = 1
Query: 118 FEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYN-CPIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILW-RDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDD--TNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDS 1317
+ ER+ L +P++Q C G+ +++D++ G+ + T ++ E L + C K + P F LLG +YG P RI K ++ L L + + + +++ D N + P +L Q S+++ E S+L Q ++ G + E + E + S +F R++ D+ I+ DD +++L+D NA QS+L + + + W RD H Y+ Q A+ V E+ +++ L Y I + Q + K CG+++++ + L D+ T+ P++L+GPP GK+ + + + L H +
Sbjct: 1 MDTEREALQCTAYPEVQSFC-QRHGLAFEVVDLRWGIPNTQATDYLTTELCLEELER---CQKTSIGPAFVALLGDQYGPCPVPRRIEEKEWEALRAQLTSRPRDL----ELVTRHFQRDDNTIPPTYVL------------QPSGSLVVPGPEEATLTSVLRGGAQEAWRL----GLISQEQWMCYHRSVIEWEIELGLLSSARGDQGATVFLRDVQDLNKHIL------DDCSLKMVDRLVDGCLDTNA--------QSLLSGLKGRILDAQPGALKSHHLSWSRDLVNPKNKAHARYLKQLSEQFVARTNHQVLEQLRELELA-RQELGWLYQEIRHHLWQSTESTKVFCGHQELLAQLRQQLRQDESRTHTPLVLFGPPGIGKTSLMCKLAQQVPELLGHKT 367
BLAST of AAA domain-containing protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268]) HSP 1 Score: 87.8113 bits (216), Expect = 1.398e-16 Identity = 85/357 (23.81%), Postives = 165/357 (46.22%), Query Frame = 1
Query: 1939 GKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLV-----DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW---VDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLA--RNGGKEIVLLEESINNSALVIE-NDLDS--LAGELIMQLLPYVSYYPNLRFLIENCDKV-----APKHNAFVPIYPSNKLPGSPLASTI-NCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEV 2952
G L++H L YI S GL++ E+ +VL+LD +V+ VY + + + +++FP LW+ ++++L LV DG +L+ L+ + V L + + H +LA +F+GAW + + I+ K + P Q ++ + N RK +L HL+ +EL + V+ + ++ + + + LLDDF + E+ L+ E+I +E L+ L EL+ +LL + + +P + + + C + A + VP+ + PG PL +T+ C + I ++ S+ ++LL+ D +D+ + + + + EV
Sbjct: 575 GALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYRDWTPP---SKELLRFPPLLWVRLRRDLGHCLVRRPVDGCMLLAIAHRQLSQVIQVRYLSGPERA---KRHGVLAEFFSGAWSQGIKKLITLPLVGKPLNLDRKVAP--QPLWFS---STVANLRKLTELPFHLLHAGRLEELKQEVLGNMSWISCRGISGGIEVLLDDFDMCAPHMNSPEVDLVREAIQLCGPAVELRGLEKSVLYTELLARLLFFAASHPAM--IGQLCQQAQSWFRACPYPMLVPLAGFLQPPGGPLRATLTGCHKGITAI-----AWSLEEKLLVVGTQDGAMVVWDVEEQQVVHVLMGHTAEV 913 HSP 2 Score: 67.3958 bits (163), Expect = 2.184e-10 Identity = 82/406 (20.20%), Postives = 156/406 (38.42%), Query Frame = 1
Query: 118 FEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYN-CPIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILW-RDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDD--TNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDS 1317
+ ER+ L +P++Q C G+ +++D++ G+ + T ++ E L + C K + P F LLG +YG P RI K ++ L L + + + +++ D N + P +L Q S+++ E S+L Q ++ G + E + E + S +F R++ D+ I+ DD +++L+D NA QS+L + + + W RD H Y+ Q A+ V E+ +++ L Y I + Q + K CG+++++ + L D+ T+ P++L+GPP GK+ + + + L H +
Sbjct: 1 MDTEREALQCTAYPEVQSFC-QRHGLAFEVVDLRWGIPNTQATDYLTTELCLEELER---CQKTSIGPAFVALLGDQYGPCPVPRRIEEKEWEALRAQLTSRPRDL----ELVTRHFQRDDNTIPPTYVL------------QPSGSLVVPGPEEATLTSVLRGGAQEAWRL----GLISQEQWMCYHRSVIEWEIELGLLSSARGDQGATVFLRDVQDLNKHIL------DDCSLKMVDRLVDGCLDTNA--------QSLLSGLKGRILDAQPGALKSHHLSWSRDLVNPKNKAHARYLKQLSEQFVARTNHQVLEQLRELELA-RQELGWLYQEIRHHLWQSTESTKVFCGHQELLAQLRQQLRQDESRTHTPLVLFGPPGIGKTSLMCKLAQQVPELLGHKT 367
BLAST of AAA domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6P5U7|NWD2_MOUSE (NACHT and WD repeat domain-containing protein 2 OS=Mus musculus OX=10090 GN=Nwd2 PE=1 SV=2) HSP 1 Score: 155.221 bits (391), Expect = 2.988e-36 Identity = 229/1000 (22.90%), Postives = 416/1000 (41.60%), Query Frame = 1
Query: 40 TSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQE--WKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSP-VIFNREIIDIKNFIVISNQKK------DDKR----KSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKF---GCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHD----SECHFITRFV-TSNCTI--AEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPR---DIEGILLSFQQQSN--KKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDG----------ILTASVIVDYFYNQNFIYNSMEEIP----CQTLGE-----FYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDV-IKDGYLLV--DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW--------------------------VDQTISF----HFDLKNPEMSY--NCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGG--KEIVLLE---ESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
T+LP + +P + F+ ++ ED ER+ L ++PKL+E C + +G+E ++ID+ G++ + Q++ + L + C + LLG+KYGN+ P + F+++L+ K +E LE +Y D N V P + + P K +QE W++ + +F+ K+ G + + + E F + K + V + R+I +I+ F+ I K D R A EKLI + +V + +L+ + Y I G+ + ++ ID +A + + N D L YD I +A F C +I++ + N P+++YG P +GK+++ A + L D S+ I RF+ T++ +I + LS+ Q++ N + + + P+ D+ + ++ +S+ + +IIL E+ SE ++ +P LP+ +++I+S+ + K L L + + I + + K+ ++ + L K T G T + V+ + + + S +++ C T+ E F++L K+ G+ L+S L YI + GL++ E+ +VL LD VMNE+ N S + ++ P +K+ L+ L++ +K+ LLV + + + L ++S+L++ H ILA YF G W +++ F FD + P+ + C P ++ F N+RK +L+ HL D+L+ +I +F +LY K + ++L D +LA N KE+ L SI N + SL+ EL +LLP VS P LR L+ CDK PK+ + VP++ S + SP
Sbjct: 28 TALP--SHLVPAGRSVRVFISANPEDTGAERQALRETVYPKLREFCRENYGLEFQVIDLYWGIEEDEWDSPELQKMRMKLLEECLKTSAGPCFVGLLGEKYGNIRIPGEVEASEFEMILDAAVEAK----LETKLLEDWYCRDENSV-PAAYYLRPRLEVPRSNKNSTQPSASSEQERPWQEISDEIKTIFKAAVKLLHEQGKMKQSQAKRYLFSAIEDEFDFALGKQTPAFLKKCVCYIRKIANIERFVKIPEMGKYMDITGTDPRIVRDPEAQEKLIKLRDEFIPTIVASSNLRVYTSVTHCDMKLGYSQEIENHYI-----EGLGKQFYEDMIDIIQATV-------------QQNFDTETDTL--YDEILQHSSLCKTYASFYEYKCESLNILHKYILPSKTGHIN-PLVVYGGPCTGKTLLLAEVAKKAYGWLHEDTGPDSDPVVIVRFLGTTDMSIDLRTLLLSVCEQLAV-------------NYRCLVQSFPKKIHDLRDLFINLLNESSLQRPLVIILDALEQLSE-ADEARKLWWLPAHLPRFVRIILSTLPN----KHGILQKLRCLIHEEDNYIEL---IPRDRKMCSQVLKHQLLRVKRKVTSGQQIYVNNAFSKCTLPMFVNLTFREVRHWRSHKDVDESSLCVTVHESIEQLFWSLE-----KKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMNELNENTRPS-----NPLRVPYLYIARLKEGLNGYLIERHVKNVTLLVWANRHLQLIAQKLYLQEDSNLREMHTILADYFLGVWSGGRRKAFCLEDPYLNGCLDLENRSLLEEEKHFMEQASFDRQAPDQPWVFQCNPLEPDIF-------FVNHRKMSELLYHLTRCGKTDDLLYGIIMNFSWLYTMIKIGQFDKVLADIELAYNYSQEKELKFLASTLRSIRNKVIAFPG---SLSAELQQRLLPVVSSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSP 958
BLAST of AAA domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9ULI1|NWD2_HUMAN (NACHT and WD repeat domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NWD2 PE=2 SV=3) HSP 1 Score: 146.362 bits (368), Expect = 1.228e-33 Identity = 215/995 (21.61%), Postives = 411/995 (41.31%), Query Frame = 1
Query: 40 TSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCV--------EPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSP-VIFNREIIDIKNFI----------VISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKF---GCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHD----SECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSF-----QQQSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVLVPEFTQTEF--------NIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWY----KRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDV-IKDGYLLV--DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW--------------------------VDQTISF----HFDLKNPEMSY--NCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGKEIVLLEESINNSALVIENDL----DSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
T+LP + +P + F+ ++ ED ER+ L ++PKL+E C + +G+E ++ID+ G++ + Q+ + L C + LLG+KYGN+ P + F+++L+ K +E LE++Y D N V + EM+ + A+ P ++ ++ W++ + +F+ K+ G + + + E F + K + V + R+I +I+ F+ + + + + A EKLI + +V + +L+ + Y I G+ + ++ ID +A I + N D L YD I +A F C +IV+ + N P+I+YG P +GK+++ A + L D S+ I RF+ + ++ ++ L + E + N + + + P+ I + F + + +II E+ SE + +P LP+ +++++S+ + ++ E E + ++ QL + +T Q + +++N L T + V+ + + + S +++ +L ++ + + K+ G+ L+S L YI + GL++ E+ +VL LD VM+E+ N S + ++ P +K+ LS L++ +K+ LLV + + + L ++ L++ H ILA YF G W +++ F FD + P+ + C P ++ F N+RK +L+ HL D+L+ +I +F +LY K + ++L D +LA N +E L + + N+ I+N + SL+ EL +LLP VS P LR L+ CDK PK+ + VP++ S + SP
Sbjct: 28 TALP--SHLVPAGRSVRVFISANPEDTGAERQALRENVYPKLREFCRENYGLEFQVIDLYWGVEEDEWDSPELQKTRMKLLENCLKTSAGPCFVGLLGEKYGNIRIPGEVEASEFEMILDAAIEAK----LETKLLEEWYCRDENSVPAAYYLRPKSEMLRSNRNAMQPSTNAEN-------EKTWQEISDEIKKIFKAAVKLLHEKGKMKHSQAKRYLFSAIEDEFDFALGKQTPAFLKKCVCYIRKIANIERFVKIPEMGKYMDITGTEPRIIRDPEAQEKLIKLRDEFIPTIVASSNLRVYTSVTHCDMKLGYSQEIENHYI-----EGLGKQFYEDMIDIIQATI-------------QQNFDTETDTL--YDEILQHSSLCKTYASFYEYKCESLNIVHNYILPSKAGHIN-PLIIYGGPCTGKTLLLAEVAKKAYGWLHEDTGPESDPVVIVRFLGTT-DMSSDLRTLLLSVC---------EQLAVNYRCLVQSYPKKIHDLCDLFINLLNESSLQRPLVIIFDALEQLSE-NDDARKLWWLPAHLPRFVRIVLSTLPNKHGILQKLRCLIHEEDNYIELIPRDRKMCSQVLKHQLLRVKRKVTSGQ-QIYVNNALSKC----TLPMFVNLTFREVRHWRSHKDVDESSLSVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMSELKENTRPS-----NPLRVPYLYIARLKEGLSGYLIERHVKNVTLLVWANRHLQLIAQKLYLQDDNDLREMHTILADYFLGVWSGGRRKAFCLEDPYLNGCLDLENRSLLEEEKHFMEQASFDRQAPDQPWVFQCNPLEPDIF-------FVNHRKMSELLYHLTRCGKTDDLLYGIIMNFSWLYTMIKIGQFDKVLSDIELAYNYSQEKEL--KFLANTLRSIKNKVTAFPGSLSAELQQRLLPVVSSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSP 958
BLAST of AAA domain-containing protein vs. UniProt/SwissProt
Match: sp|Q149M9|NWD1_HUMAN (NACHT domain- and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=NWD1 PE=1 SV=3) HSP 1 Score: 90.5077 bits (223), Expect = 1.394e-16 Identity = 89/376 (23.67%), Postives = 169/376 (44.95%), Query Frame = 1
Query: 1876 IPCQTLGEFYALNL-NRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDD--KNSHLKDFHQILAGYFNGAWVDQT---ISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIE---NDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAP-----KHNAFVPIYPSNKLPGSPLASTIN-CPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEV 2952
+P T E L R + G+ L++H L YI S GL++ E+ +VL+LD +V+ +VY + + + +++FP LW+ ++++L L DG+ L+ +A VE + + S H +LA +F+G W T I+ K + P Q ++ + N RK ++L HL+ +EL + V+ ++ + + + +LLDDF L E+ L+ E++ +E + L EL+ +L + + +P L + + C + H VP+ + PG PL +T++ C + I ++ + ++LL+ D +D+ + + +GEV
Sbjct: 553 VPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYRDWTPP---SKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLITLPLVGKPLNLDRKVAP--QPLWFS---HTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCAPHLDSPEVGLVREALQLCRPAVELRGMERSLLYTELLARLHFFATSHPAL--VGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAM-----AWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTGHTGEV 913 HSP 2 Score: 67.3958 bits (163), Expect = 1.576e-9 Identity = 82/398 (20.60%), Postives = 161/398 (40.45%), Query Frame = 1
Query: 148 RIFPKLQEQCF-DEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYN-CPIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILW-RDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKC-YDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDT--NVPIILYGPPNSGKSIVFARTIFEFQSSLPHDS 1317
R P L+ Q F G+ +++D++ G+ + T ++ E +++ C K + P F L+G +YG P IP++I + E L++H + + +Y+ D N P +L Q + C+ E S+L + Q ++ G + E + E ++ S D + +F REI D+ I+ +D +++L AD ++ D Q++L + +++ R+ W RD H Y+ + + V R ++ LD + L Y I + Q ++ + CG ++++ + L DD+ + P++L+GPP GK+ + + + L H +
Sbjct: 8 RALPTLKCQTFCQRHGLMFEVVDLRWGIRNIEATDHLTTELCLEEVDR---CWKTSIGPAFVALIGDQYG----PCLIPSRIDEKEWEVLRDHLTARPSDLELVARYFQRDENAFPPTYVL------------QAPGTGEACEPEEATLTSVLRSGAQEARRL----GLITQEQWQHYHRSVIEWEIERSLLSSEDREQGATVFLREIQDLHKHIL------EDCALRMVDRL--------ADGCLDADAQNLLSSLKSHITDMHPGVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRE--LDTAGQELAWLYQEIRHHLWQSSEVIQTFCGRQELLARLGQQLRHDDSKQHTPLVLFGPPGIGKTALMCKLAEQMPRLLGHKT 366
BLAST of AAA domain-containing protein vs. UniProt/SwissProt
Match: sp|A6H603|NWD1_MOUSE (NACHT domain- and WD repeat-containing protein 1 OS=Mus musculus OX=10090 GN=Nwd1 PE=2 SV=2) HSP 1 Score: 87.8113 bits (216), Expect = 9.377e-16 Identity = 83/341 (24.34%), Postives = 159/341 (46.63%), Query Frame = 1
Query: 1939 GKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLV-----DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW---VDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLA--RNGGKEIVLLEESINNSALVIE-NDLDS--LAGELIMQLLPYVSYYPNLRFLIENCDKV-----APKHNAFVPIYPSNKLPGSPLASTI-NCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDL 2904
G L++H L YI S GL++ E+ +VL+LD +V+ VY + + + +++FP LW+ ++++L LV DG +L+ L+ + V L + + H +LA +F+GAW + + I+ K + P Q ++ + N RK +L HL+ +EL + V+ + ++ + + + LLDDF + E+ L+ E+I +E L+ L EL+ +LL + + +P + + + C + A + VP+ + PG PL +T+ C + I ++ S+ ++LL+ D +D+
Sbjct: 575 GALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYRDWTPP---SKELLRFPPLLWVRLRRDLGHCLVRRPVDGCMLLAIAHRQLSQVIQVRYLSGPERA---KRHGVLAEFFSGAWSQGIKKLITLPLVGKPLNLDRKVAP--QPLWFS---STVANLRKLTELPFHLLHAGRLEELKQEVLGNMSWISCRGISGGIEVLLDDFDMCAPHMNSPEVDLVREAIQLCGPAVELRGLEKSVLYTELLARLLFFAASHPAM--IGQLCQQAQSWFRACPYPMLVPLAGFLQPPGGPLRATLTGCHKGITAI-----AWSLEEKLLVVGTQDGAMVVWDV 897 HSP 2 Score: 67.3958 bits (163), Expect = 1.377e-9 Identity = 82/406 (20.20%), Postives = 156/406 (38.42%), Query Frame = 1
Query: 118 FEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYN-CPIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILW-RDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDD--TNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDS 1317
+ ER+ L +P++Q C G+ +++D++ G+ + T ++ E L + C K + P F LLG +YG P RI K ++ L L + + + +++ D N + P +L Q S+++ E S+L Q ++ G + E + E + S +F R++ D+ I+ DD +++L+D NA QS+L + + + W RD H Y+ Q A+ V E+ +++ L Y I + Q + K CG+++++ + L D+ T+ P++L+GPP GK+ + + + L H +
Sbjct: 1 MDTEREALQCTAYPEVQSFC-QRHGLAFEVVDLRWGIPNTQATDYLTTELCLEELER---CQKTSIGPAFVALLGDQYGPCPVPRRIEEKEWEALRAQLTSRPRDL----ELVTRHFQRDDNTIPPTYVL------------QPSGSLVVPGPEEATLTSVLRGGAQEAWRL----GLISQEQWMCYHRSVIEWEIELGLLSSARGDQGATVFLRDVQDLNKHIL------DDCSLKMVDRLVDGCLDTNA--------QSLLSGLKGRILDAQPGALKSHHLSWSRDLVNPKNKAHARYLKQLSEQFVARTNHQVLEQLRELELA-RQELGWLYQEIRHHLWQSTESTKVFCGHQELLAQLRQQLRQDESRTHTPLVLFGPPGIGKTSLMCKLAQQVPELLGHKT 367
BLAST of AAA domain-containing protein vs. TrEMBL
Match: A0A267EA39 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033440g1 PE=4 SV=1) HSP 1 Score: 628.246 bits (1619), Expect = 0.000e+0 Identity = 429/1479 (29.01%), Postives = 723/1479 (48.88%), Query Frame = 1
Query: 31 LIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEP----EMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNAD-LVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQF-EAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTD--DDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQ---FETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKC-----SEVGSQSLVTDLIPKFLPKNLKLIVSSTDS-----FDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLL-----VDLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW--VDQTISFHFDLKNPEMSYNCCPKSQKMYA-------------KKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSPLASTINCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEVYYGPNRDIILVLETEYRQIIKVHQRETGDLLGQIIPMNWVVLRPFEERNEYRITNIDMNQTKMALIITNEVSYLFVLNLETLEPILAFNPGLRLEMLKLTPDESTVFTHHVERLVSLNVEKNQLNSAVELQGIPLQMLFANEQSKKAFIVCDQQKSVVVLDLESAGVVRKCYKISFENCLDENDYVLEVSCSEIGNPFLLIMSCHSVILYDWNKEKVLNHITRPSQLPVYFKLPNRLDNQPASLKFNAAKLILSDRVIICALFRDVIVCTVSDNKIIKTLHAPVGGIVSEIHI--ADDYIIGKVEQSQNSAEVMIWKTDPKCLFFKIENNQDKLTRCVKKIQIG--GSVAIASCVESDEMGVIEISTGTLVDLYSHSSVVINCCLSSCGKWALVTV--KNSHNANILWSLETRKIIFEFGSSTNTEFIVPMKSKSGFYCITNHSKSIDAPNFIVTQILCDLGVE 4326
L LP ++ I F + S+F DFE ER++L N +P+L E + +G++ + +DIKLGL+ Y +F++ K + P+ LLGQK+G L P R+P++ F+L+ TL+ H+ + + L+ +Y D N P E +L+ PD+ +D + EWK T +L+NLF+ ICL GT+D + +I E +A S + S ++F PV+F R+IID+KN++ N+ K D DV + D +I++ L +L Q N Y + + +F +LWR G+ + H+ Y+ F EAFI A V R + + ++ +D + A F E + A+++Y D N +L G N+GK A+ E Q L I R V ++++ S+F QI + NS E PR+++ ++ ++++ E+ + QSLV P+ P N+KL++++ D P+ + + T + F + L + LT EQ R+ L + + AS++ D + + L + +R +FG+ +SH Y+ S GGLTD EV ++L+LD V++E+ + + + +FP S+WLL+KQE+ +++ + DGY + D+ + V+ L D K H +A YF G W V + +S + + P + MY+ + G+ FYN RKFRQL RHL D EL V+F +D+LY K+ AL + E L DFQL + E+ L+EE+I + ++ ++L++LA EL L+ Y Y N++ L+ D +HN FVP Y KLPGS L ST+ CP ++S+ + S L +KLK+D Y YDL G + SSGE++ + ++++ R +KVH G +G I+P+NW+ PFEE++ +RIT + + + +A I+ + +S + + +L T +PI F P R + +TPDE +FT++ E+++ + S V+L +P +++F + S +AFI+C+ ++ VV+L +++ G + +KI FEN L +D + ++ S+ LL+ + +V++Y++ ++ ++ HI RP ++P FK+PN + F+ A DRV+I ++FRDV+V V + + LHAP GI++ + + ++G +E S+ E+ +W F D LT ++ ++ A+A C SDEMGV+++ TG L DLYSH VV++C +SSCG +A+ +V +N + NI+WSL R+I+ EFG+ ++P + S Y + + P I L D V
Sbjct: 8 LCSGRLPLSSLPTVSPRSITFCIISAFSDFEKEREVLRNEAYPRLYEYFRNTYGLQFRGVDIKLGLEKVNYDELDYWDLFHDIKRKFAFASHDSVPVILLGQKFGLPLLPRRLPSRAFELIRATLRAHRNPLTAQYHILDSWYRRDENAECPDGDTEHVLLPASRQLPDIVGEDPEAKASALAEWKFTARLLANLFKIGVGICLREGTMDDQTAFEILTFELDAGISHLLSHSDLTQFRPVVFERDIIDLKNYL---NEPKADL-------YTDVELDEENDRFLIDKSLADLL-QELNDRLTTYASVDRQFSVLWRFPDGIDKRLHEEYLGDFCEAFIEAAKT-AVESRLAGKQMHADSEVVRVFDDAWTSLEHCRLLAPFSLRQEATIEAVVEYCVDFSARQNYTYLLLGGQNTGKMPAIAQAFIEIQQRLCESPVGVLIPRVVMFERRLSDLTASLFNQIRTCCRLDTGGVVATGAGANSAEQTAPPPRNLQELVDRLSGAG--PVVLLIAGAERLVDDAGDRLPPQSLVP--APRGPPSNVKLVLTALDEAGGSVLSLAGPHLRVLHIGPQTADAYREFARHYLAERSRRLTAEQ-WRWAEQRLAGLESMFHASLLCDRLARLASGDDPADLPASSGLADLLDAEFDRLEAKFGRIAVSHAFAYVSLSGGGLTDIEVKDLLSLDDAVLDEMLVP------IEDGVRQFPSSVWLLMKQEVRLLIHEASFDGYFVNYWANGDVESAVAARYLSSDDLR--KSLHFTMADYFLGTWHGVSKPVSTVSSADDVSSADRLMPTQKLMYSIEGETGGSVTSGGGQQGS-FYNERKFRQLPRHLFLSDRVPELNNLVLFSYDWLYYKSAALGLEETLRDFQLVPSN-TEVSLVEETIRKAFDILGDNLNNLAAELSGSLVLYSHEYKNIKNLVRQADVRGCQHNIFVPCYSYAKLPGSALQSTVECPSNLQSM----HLSSETATLYVKLKDDVSLYKYDLERGTMLGEARTSSGELHLSADERYAVMVDDRKRSHLKVHLCSDGSFVGHILPLNWIDTMPFEEKSMFRITKVRVARRLVACIVASRMSSVIIADLATCQPIHVFKPDRRAALCDITPDERFIFTNNGEQVLVFEIGNGVQTSVVDLLAVPKRLMFTRDGS-RAFIMCEGEQKVVILYMDAKGAIEMSFKIMFENSLG-DDRLQDMRVSQ-AEQLLLVRAEKNVLVYEFGRDAIVAHIRRPPEIPAEFKMPN---ANYERINFSEADFAFGDRVVITSIFRDVLVWEVEQGRPLVMLHAPT-GILTRLLVDQTRSLVVGFIEHSR---EIHLWSLQGA---FTDGTAVDSLTAPIRAVRSARRRPRAVACCDNSDEMGVVDLDTGYLTDLYSHEGVVVDCAISSCGDYAVASVVQRNPNTTNIVWSLSERRILAEFGNVPG--HLLPCRHSSDVYIVDQAEVAFKQPFGITRLALGDGAVR 1440
BLAST of AAA domain-containing protein vs. TrEMBL
Match: A0A267FKI0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033440g3 PE=4 SV=1) HSP 1 Score: 626.706 bits (1615), Expect = 0.000e+0 Identity = 427/1479 (28.87%), Postives = 724/1479 (48.95%), Query Frame = 1
Query: 31 LIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEP----EMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNAD-LVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQF-EAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTD--DDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQ---FETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKC-----SEVGSQSLVTDLIPKFLPKNLKLIVSSTDS-----FDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLL-----VDLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW--VDQTISFHFDLKNPEMSYNCCPKSQKMYA-------------KKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSPLASTINCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEVYYGPNRDIILVLETEYRQIIKVHQRETGDLLGQIIPMNWVVLRPFEERNEYRITNIDMNQTKMALIITNEVSYLFVLNLETLEPILAFNPGLRLEMLKLTPDESTVFTHHVERLVSLNVEKNQLNSAVELQGIPLQMLFANEQSKKAFIVCDQQKSVVVLDLESAGVVRKCYKISFENCLDENDYVLEVSCSEIGNPFLLIMSCHSVILYDWNKEKVLNHITRPSQLPVYFKLPNRLDNQPASLKFNAAKLILSDRVIICALFRDVIVCTVSDNKIIKTLHAPVGGIVSEIHI--ADDYIIGKVEQSQNSAEVMIWKTDPKCLFFKIENNQDKLTRCVKKIQIG--GSVAIASCVESDEMGVIEISTGTLVDLYSHSSVVINCCLSSCGKWALVTV--KNSHNANILWSLETRKIIFEFGSSTNTEFIVPMKSKSGFYCITNHSKSIDAPNFIVTQILCDLGVE 4326
L LP ++ I F + S+F DFE ER++L N +P+L E + +G++ + +DIKLGL+ Y +F++ K + P+ LLGQK+G L P R+P++ F+L+ TL+ H+ + + L+ +Y D N P E +L+ PD+ +D + EWK T +L+NLF+ ICL GT+D + +I E +A S + S ++F P++F R+IID+KN++ N+ K D DV + D +I++ L +L Q N Y + + +F +LWR G+ + H+ Y+ F EAFI A V R + + ++ +D + A F E + A+++Y D N +L G N+GK A+ E Q L I R V ++++ S+F QI + NS E PR+++ ++ ++++ E+ + QSLV P+ P N+KL++++ D P+ + + T + F + L + LT EQ R+ L + + AS++ D + + L + +R +FG+ +SH Y+ S GGLTD EV ++L+LD V++E+ + + + +FP S+WLL+KQE+ +++ + DGY + D+ + V+ L D K H +A YF G W V + +S + + P + MY+ + G+ FYN RKFRQL RHL D EL V+F +D+LY K+ AL + E L DFQL + E+ L+EE+I + ++ ++L++LA EL L+ Y Y N++ L+ D +HN FVP Y KLPGS L ST+ CP ++S+ + S L +KLK+D Y YDL G + SSGE++ + ++++ R +KVH G +G I+P+NW+ PFEE++ +RIT + +++ +A I+ + +S + + +L T +PI F P R + +TPDE +FT++ E+++ + S V+L +P +++F + S +AFI+C+ ++ VV+L +++ G + +KI F+N L +D + ++ S+ LL+ + +V++Y++ ++ ++ HI RP ++P FK+PN + F+ A DRV+I ++FRDV+V V + + LHAP GI++ + + ++G +E S+ E+ +W F D LT ++ ++ A+A C SDEMGV+++ TG L DLYSH VV++C +SSCG +A+ +V +N + NI+WSL R+I+ EFG+ ++P + S Y + + P I L D V
Sbjct: 8 LCSGRLPLSSLPTVSPRSITFCIISAFSDFEKEREVLRNEAYPRLYEYFRNTYGLQFRGVDIKLGLEKVNYDELDYWDLFHDIKRKFAFASHDSVPVILLGQKFGLPLLPRRLPSRAFELIRATLRAHRNPLTAQYHILDSWYRRDENAECPDGDTEHVLLPASRQLPDIVGEDPEAKASALAEWKFTARLLANLFKIGVGICLREGTMDDQTAFEILTFELDAGISHLLSHSDLTQFRPIVFERDIIDLKNYL---NEPKADL-------YTDVELDEENDRFLIDKSLADLL-QELNDRLTTYASVDRQFSVLWRFPDGIDKRLHEEYLGDFCEAFIEAAKT-AVESRLAGKQMHADSEVVRVFDDAWTSLEHCRLLAPFSLRQEATIEAVVEYCVDFSARQNYTYLLLGGQNTGKMPAIAQAFIEIQQRLCESPVGVLIPRVVMFERRLSDLTASLFNQIRTCCRLDTGGVVATGAGANSAEQTAPPPRNLQELVDRLSGAG--PVVLLIAGAERLVDDAGDRLPPQSLVP--APRGPPSNVKLVLTALDEAGGSVLSLAGPHLRVLHIGPQTADAYREFARHYLAERSRRLTAEQ-WRWAEQRLAGLESMFHASLLCDRLARLASGDDPADLPASSGLADLLDAEFDRLEAKFGRIAVSHAFAYVSLSGGGLTDIEVKDLLSLDDAVLDEMLVP------IEDGVRQFPSSVWLLMKQEVRLLIHEASFDGYFVNYWANGDVESAVAARYLSSDDLR--KSLHFTMADYFLGTWHGVSKPVSTVSSADDVSSADRLMPTQKLMYSIEGETGGSVTSGGGQQGS-FYNERKFRQLPRHLFLSDRVPELNNLVLFSYDWLYYKSAALGLEETLRDFQLVPSN-TEVSLVEETIRKAFDILGDNLNNLAAELSGSLVLYSHEYKNIKNLVRQADVRGCQHNIFVPCYSYAKLPGSALQSTVECPSNLQSM----HLSSETATLYVKLKDDVSLYKYDLERGTMLGEARTSSGELHLSADERYAVMVDDRKRSHLKVHLCSDGSFVGHILPLNWIDTMPFEEKSMFRITKVRVSRRLVACIVASRMSSVIIADLATCQPIHVFKPDRRAALCDITPDERFIFTNNGEQVLVFEIGNGVQTSVVDLLAVPKRLMFTRDGS-RAFIMCEGEQKVVILYMDAKGAIEMSFKIMFDNSLG-DDRLQDMRVSQ-AEQLLLVRAEKNVLVYEFGRDAIVAHIRRPPEIPAEFKMPN---ANYERINFSEADFAFGDRVVITSIFRDVLVWEVEQGRPLVMLHAPT-GILTRLLVDQTRSLVVGFIEHSR---EIHLWSLQGA---FTDGTAVDSLTAPIRAVRSARRRPRAVACCDNSDEMGVVDLDTGYLTDLYSHEGVVVDCAISSCGDYAVASVVQRNPNTTNIVWSLSERRILAEFGNVPG--HLLPCRHSSDVYIVDQAEVAFKQPFGITRLALGDGAVR 1440
BLAST of AAA domain-containing protein vs. TrEMBL
Match: A0A267G6I1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033440g2 PE=4 SV=1) HSP 1 Score: 621.698 bits (1602), Expect = 0.000e+0 Identity = 427/1479 (28.87%), Postives = 720/1479 (48.68%), Query Frame = 1
Query: 31 LIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEP----EMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNAD-LVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQF-EAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTD--DDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQ---FETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKC-----SEVGSQSLVTDLIPKFLPKNLKLIVSSTDS-----FDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLL-----VDLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW--VDQTISFHFDLKNPEMSYNCCPKSQKMYA-------------KKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSPLASTINCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEVYYGPNRDIILVLETEYRQIIKVHQRETGDLLGQIIPMNWVVLRPFEERNEYRITNIDMNQTKMALIITNEVSYLFVLNLETLEPILAFNPGLRLEMLKLTPDESTVFTHHVERLVSLNVEKNQLNSAVELQGIPLQMLFANEQSKKAFIVCDQQKSVVVLDLESAGVVRKCYKISFENCLDENDYVLEVSCSEIGNPFLLIMSCHSVILYDWNKEKVLNHITRPSQLPVYFKLPNRLDNQPASLKFNAAKLILSDRVIICALFRDVIVCTVSDNKIIKTLHAPVGGIVSEIHI--ADDYIIGKVEQSQNSAEVMIWKTDPKCLFFKIENNQDKLTRCVKKIQIG--GSVAIASCVESDEMGVIEISTGTLVDLYSHSSVVINCCLSSCGKWALVTV--KNSHNANILWSLETRKIIFEFGSSTNTEFIVPMKSKSGFYCITNHSKSIDAPNFIVTQILCDLGVE 4326
L LP ++ I F + S+F DFE ER++L N +P+L E + +G++ + +DIKLGL+ Y +F++ K + P+ LLGQK+G L P R+P++ F L+ TL+ H+ + L+ +Y D N P E +L+ PD+ +D + EWK T +L+NLF+ ICL GT+D + +I E +A S + S ++F P++F R+IID+KN++ N+ K D DV + D +I++ L +L Q N Y + + +F +LWR G+ + H+ Y+ F EAFI A V R + + ++ +D + A F E + A+++Y D N +L G N+GK A+ E Q L I R V ++++ S+F QI + NS E PR+++ ++ ++++ E+ + QSLV P+ P N+KL++++ D P+ + + + + F + L + LT EQ R+ L + + AS++ D + + L + +R +FG+ +SH Y+ S GGLTD EV ++L+LD V++E+ + + + +FP S+WLL+KQE+ +++ + DGY + D+ + V+ L D K H +A YF G W V + +S + + P + MY+ + G+ FYN RKFRQL RHL D EL V+F +D+LY K+ AL + E L DFQL + E+ L+EE+I + ++ +L++LA EL L+ Y Y N++ L+ D +HN FVP Y KLPGS L ST+ CP ++S+ + S L +KLK+D Y YDL G + SSGE++ + ++++ R +KVH G +G I+P+NW+ PFEE++ +RIT + + + +A I+ + +S + + +L T +PI F P R + +TPDE +FT++ E+++ + S V+L +P +++F + S +AFI+C+ ++ VV+L +++ G + +KI FEN L +D + ++ S+ LL+ + +V++Y++ ++ ++ HI RP ++P FK+PN + F+ A DRV+I ++FRDV+V V + + LHAP GI++ + + ++G +E S+ E+ +W F D LT ++ ++ A+A C SDEMGV+++ TG L DLYSH VV++C +SSCG +A+ +V +N + NI+WSL R+I+ EFG+ ++P + S Y + + P I L D V
Sbjct: 8 LCSGRLPLSSLPTVSPRSITFCIISAFSDFEKEREVLRNEAYPRLYEYFRNTYGLQFRGVDIKLGLEKVNYDELDYWDLFHDIKRKFAFASHDSVPVILLGQKFGLPLLPRRLPSRAFDLIRATLRAHRNPLTAQYYILDSWYRRDDNAECPDGDTEHVLLPASRQLPDIVGEDPEAKASALAEWKFTARLLANLFKIGVGICLREGTMDDQTAFEILTFELDAGISHLLSHSDLTQFRPIVFERDIIDLKNYL---NEPKADL-------YTDVELDEENDRYLIDKSLADLL-QELNDRLTTYASVDRQFSVLWRFPDGIDKRLHEEYLGDFCEAFIEAAKT-AVESRLAGKQMHADSEVVRVFDDAWTSLEHCRLLAPFSLRQEATIEAVVEYCVDFSARQNYTYLLLGGQNTGKMPAIAQAFIEIQQRLCESPVGVLIPRVVMFERRLSDLTASLFNQIRTCCRLDTGGVVATGAGANSTEQTAPPPRNLQELVDRLSGAG--PLVLLIAGAERLVDDAGDRLPPQSLVP--APRGPPSNVKLVLTALDEAGGSVLSLAGPHLRVLHIGPQSADAYREFARHYLAERSRRLTAEQ-WRWAEQRLAGLESMFHASLLCDRLARLASGDDPADLPANSGLADLLDAEFDRLEAKFGRIAVSHAFAYVSLSGGGLTDIEVKDLLSLDDAVLDEMLVP------IEDGVRQFPSSVWLLMKQEVRLLIHEASFDGYFVNYWANGDVESAVAARYLSSDDLR--KSLHFTMADYFLGTWHGVSKPVSTVSSADDVSSADRLMPTQKLMYSIEGETGGSVTSGGGQQGS-FYNERKFRQLPRHLYLSDRVPELNNLVLFSYDWLYYKSAALGLEETLRDFQLVPSN-TEVSLVEETIRKAFDILGENLNNLAAELSGSLVLYSHEYKNIKNLVRQADVRGCQHNIFVPCYSYAKLPGSALQSTVECPSNLQSM----HLSSETATLYVKLKDDVSLYKYDLERGTMLGEARTSSGELHLSADERYAVMVDNRKRSHLKVHLCSDGSFVGHILPLNWIDTMPFEEKSMFRITKVRVARRLVACIVASRMSSVIIADLATCQPIHVFKPDRRAALCDITPDERFIFTNNGEQVLVFEIGNGVQTSVVDLLAVPKRLMFTRDGS-RAFIMCEGEQKVVILYMDAKGAIEMSFKIMFENSLG-DDRLQDMRVSQ-AEQLLLVRAEKNVLVYEFGRDAIVAHIRRPPEIPAEFKMPN---ANYERINFSEADFAFGDRVVITSIFRDVLVWEVEQGRPLVMLHAPT-GILTRLLVDQTRSLVVGFIEHSR---EIHLWSLQGA---FTDGTAVDSLTAPIRAVRSARRRPRAVACCDNSDEMGVVDLDTGYLTDLYSHEGVVVDCAISSCGDYAVASVVQRNPNTTNIVWSLSERRILSEFGNVPG--HLLPCRHSSDVYIVDQAEVAFKQPFGITRLALSDGAVR 1440
BLAST of AAA domain-containing protein vs. TrEMBL
Match: A0A1I8JLX6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 597.43 bits (1539), Expect = 5.433e-179 Identity = 455/1703 (26.72%), Postives = 788/1703 (46.27%), Query Frame = 1
Query: 31 LIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEP----EMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNAD-LVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQF-EAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTD--DDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKC-----SEVGSQSLVTDLIPKFLPKNLKLIVSSTDS-----FDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLL-----VDLATTVSVESLIDDKNSHLKDFHQILAGYFNGAW--VDQTISFHFDLKNPEMSYNCCPKSQKMYA------------KKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSPLASTINCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEVYYGPNRDIILVLETEYRQIIKVHQRETGDLLGQIIPMNWVVLRPFEERNEYRITNIDMNQTKMALIITNEVSYLFVLNLETLEPILAFNPGLRLEMLKLTPDESTVFTHHVERLVSLNVEKNQLNSAVELQGIPLQMLFANEQSKKAFIVCDQQKSVVVLDLESAGVVRKCYKISFENCLDENDYVLEVSCSEIGNPFLLIMSCHSVILYDWNKEKVLNHITRPSQLPVYFKLPNRLDNQPASLKFNAAKLILSDRVIICALFRDVIVCTVSDNKIIKTLHAPVGGIVSEIHI--ADDYIIGKVEQSQNSAEVMIWKTDPKCLFFKIENNQDKLTRCVKKIQIG--GSVAIASCVESDEMGVIEISTGTLVDLYSHSSVVINCCLSSCGKWALVTV--KNSHNANILWSLETRKIIFEFGSSTNTEFIVPMKSKSGFYCITNHSKSIDAPNFIVTQILCDLGVEISYTIKVLEISCLGFLTEPPCILNDDKELAFLSSN-------YRTEN-----GVGTGTNSLILWSRETHTNQNGMSKIITVKE--------------FSEQINRSVEDILSITTTKSMEDVLFIFFKTHDHEIDILHFNCHTGLVIQFMELFDVLPKQMDHKELFLSNNGCYVFYQKTSAIVNLSSGEFIGNISSDANNEYAFQCFVLKDTILILSQKTKLLAYRLPE 4932
L LP ++ I F + S+F DFE ER++L N +P+L E + +G++ + +DIKLGL+ Y +F++ K + P+ LLGQ + F L+ TL+ H+ + L+ +Y D N P E +L+ PD+ +D + EWK T +L+NLF+ ICL GT+D + +I E +A S + S ++F P++F R+IID+KN++ N+ K D DV + D +I++ L +L Q N Y + + +F +LWR G+ + H+ Y+ F EAFI A V R + + ++ +D + A F E + A+++Y D N +L G N+GK A+ E Q L C + +I L ++ NS E PR+++ ++ ++++ E+ + QSLV P+ P N+KL++++ D P+ + + + + F + L + LT EQ R+ L + + AS++ D + + L + +R +FG+ +SH Y+ S GGLTD EV ++L+LD V++E+ + + + +FP S+WLL+KQE+ +++ + DGY + D+ + V+ L D K H +A YF G W V + +S + + P + MY+ FYN RKFRQL RHL D EL V+F +D+LY K+ AL + E L DFQL + E+ L+EE+I + ++ +L++LA EL L+ Y Y N++ L+ D +HN FVP Y KLPGS L ST+ CP ++S+ + S L +KLK+D Y YDL G + SSGE++ + ++++ R +KVH G +G I+P+NW+ PFEE++ +RIT + + + +A I+ + +S + + +L T +PI F P R + +TPDE +FT++ E+++ + S V+L +P +++F + S +AFI+C+ ++ VV+L +++ G + +KI FEN L +D + ++ S+ LL+ + +V++Y++ ++ ++ HI RP ++P FK+PN + F+ A DRV+I ++FRDV+V V + + LHAP GI++ + + ++G +E S+ E+ +W F D LT ++ ++ A+A C SDEMGV+++ TG L DLYSH VV++C +SSCG +A+ +V +N + NI+WSL R+I+ EFG+ ++P + S Y + + P F +T++ G E + + L P + +D+ + L++ Y E GTG LI S + + +I+ V+ + +++ + S + + V+ I +++ L C ++LP D L S +G Y + + ++++G + A + F+CF L D++++ S+ ++ AYR+PE
Sbjct: 8 LCSGRLPLSSLPTVSPRSITFCIISAFSDFEKEREVLRNEAYPRLYEYFRNTYGLQFRGVDIKLGLEKVNYDELDYWDLFHDIKRKFAFASHDSVPVILLGQ------------NRAFDLIRATLRAHRNPLTAQYYILDSWYRRDDNAECPDGDTEHVLLPASRQLPDIVGEDPEAKASALAEWKFTARLLANLFKIGVGICLREGTMDDQTAFEILTFELDAGISHLLSHSDLTQFRPIVFERDIIDLKNYL---NEPKADL-------YTDVELDEENDRYLIDKSLADLL-QELNDRLTTYASVDRQFSVLWRFPDGIDKRLHEEYLGDFCEAFIEAAKT-AVESRLAGKQMHADSEVVRVFDDAWTSLEHCRLLAPFSLRQEATIEAVVEYCVDFSARQNYTYLLLGGQNTGKMPAIAQAFIEIQQRL-----CE--------SPLFNQIRTCCRLDTGGVVATGAG-----ANSTEQTAPPPRNLQELVDRLS--GAGPLVLLIAGAERLVDDAGDRLPPQSLVP--APRGPPSNVKLVLTALDEAGGSVLSLAGPHLRVLHIGPQSADAYREFARHYLAERSRRLTAEQ-WRWAEQRLAGLESMFHASLLCDRLARLASGDDPADLPANSGLADLLDAEFDRLEAKFGRIAVSHAFAYVSLSGGGLTDIEVKDLLSLDDAVLDEMLVP------IEDGVRQFPSSVWLLMKQEVRLLIHEASFDGYFVNYWANGDVESAVAARYLSSDDLR--KSLHFTMADYFLGTWHGVSKPVSTVSSADDVSSADRLMPTQKLMYSIEGETGGSVTSGGGQQGSFYNERKFRQLPRHLYLSDRVPELNNLVLFSYDWLYYKSAALGLEETLRDFQLVPSN-TEVSLVEETIRKAFDILGENLNNLAAELSGSLVLYSHEYKNIKNLVRQADVRGCQHNIFVPCYSYAKLPGSALQSTVECPSNLQSM----HLSSETATLYVKLKDDVSLYKYDLERGTMLGEARTSSGELHLSADERYAVMVDNRKRSHLKVHLCSDGSFVGHILPLNWIDTMPFEEKSMFRITKVRVARRLVACIVASRMSSVIIADLATCQPIHVFKPDRRAALCDITPDERFIFTNNGEQVLVFEIGNGVQTSVVDLLAVPKRLMFTRDGS-RAFIMCEGEQKVVILYMDAKGAIEMSFKIMFENSLG-DDRLQDMRVSQ-AEQLLLVRAEKNVLVYEFGRDAIVAHIRRPPEIPAEFKMPN---ANYERINFSEADFAFGDRVVITSIFRDVLVWEVEQGRPLVMLHAPT-GILTRLLVDQTRSLVVGFIEHSR---EIHLWSLQGA---FTDGTAVDSLTAPIRAVRSARRRPRAVACCDNSDEMGVVDLDTGYLTDLYSHEGVVVDCAISSCGDYAVASVVQRNPNTTNIVWSLSERRILSEFGNVPG--HLLPCRHSSDVYIVDQAEVAFKQP-FGITRLALACG----------ESASIPHLLGRPFLTGNDRLIVCLTARDLDCARAYYIEPCLFTWNTGTGQTRLIGPSMLSAFGL--VRRILAVQPCLAGSDEGGSDVVVVYTEEEEALDSVRSPDQRRFTQSVMII-------DVETLTLRCLAP---------NLLPAGTDPDRLSFSRSGEYCV-DADNYLYSVAAGL---PLRRAAPAGFQFRCFALADSLMLFSRGRRVRAYRVPE 1602
BLAST of AAA domain-containing protein vs. TrEMBL
Match: A0A1S3JCC0 (NACHT and WD repeat domain-containing protein 2 OS=Lingula unguis OX=7574 GN=LOC106171981 PE=4 SV=1) HSP 1 Score: 452.21 bits (1162), Expect = 1.142e-127 Identity = 435/1794 (24.25%), Postives = 808/1794 (45.04%), Query Frame = 1
Query: 67 LPER--NVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNC-PIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSII-ICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYS-QNADLVINEDLQSVLRQYYNSCNEIYEASE--PKFRILWRDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSF-----QQQSNKKFIIILHDFEKCS-EVGSQSLVTDLIPKFLPKNLKLIVSST-------DSFDT---RKP-YFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDDKNSHLKD------FHQILAGYFNGAWVDQTISFHFD--------LKNPEMSYNCCPKSQKM-YAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSPLASTINCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEVYYGPNRDIILVLETEYRQIIKVHQRETGDLLGQIIPMNWVVLRPFEERNEYRITNIDMNQTKMALIITNEVSYLFVLNLETLEPILAFNPGLRLEMLKLTPDESTVFTHHVERLVSLNVEKNQLNSAVELQGIPLQMLFANEQSKKAFIVCDQQKSVVVLDLESAGVVRKCYKISFENCLDENDYVLEVSCSEIGNPFLLIMSCHSVILYDWNKEKVLNHITRPSQLPVYFKLPNRLDNQPASLKFNAAKLILSDRVIICALFRDVIVCTVSDNKIIKTLHAPVGGIVSEIHIADDY--IIGKVEQSQNSAEVMIWKTDPKCLFFKIENNQDKLTRCVKKIQI--GGSVAIASCVESDEMGVIEISTGTLVDLYSHSSVVINCCLSSCGKWALVTVKNSHNA--NILWSLETRKIIFEFGSSTNTEFIVPMKSKSGFYCITNHSKSIDAPNFI---------VTQILCDLGVEISYTIKVLEISCLGFLTEPPCILNDDKELAFLSSNYRTENGVGTGTNSLILWSRETHTNQNGMSKIITVKEFSEQINRS---VEDILSITTTKSMEDVLFIFFKTHDHE-------------IDILHFNCHTGLVIQFMELFDVLPKQMDHKELFLSNNGCYVFYQKTSAIVNLSSGEFIGNISSDANNEYAFQCFVLKDTILILSQKTKLLAYRLPEICKIGQIELKDEVSCVSKCLDDFTIMVGCVDGSVLSYSLIDIFSPYSFLSQIKVVRNFLPTTRSP---TIELESIRSLNKTELSQEFDNLIAIKRPISEP 5223
LPE V+ +V + D ER L +++PKL+E C ++ GIE++++D++ G+ + ++F + L + C + + P F L+GQ+YG+ P IP +++L +L+ ++ R + L+ +Y D N + P +L I ++ D + + + Q++W T++ L L Q +++C G++D K F+ EFE I + + + +F REI D+KN++ N K +D+ ++ + L I+ D Q L N + + KF ILWR + V H+ YI+ F V+ + ++A + A + +D + L + + G E+I+ + Y+T + P++L+G GK+ VFA+ E +P +C I R++ N A+I I+ + L E E++IP D + +L F ++ ++ E + E + LV +P+ L N+K+++S+ D T + P YF+ V P + + ++ L G+ ++++Q R + + L + V+ ++ T+ + + ++ GKTL+SH L Y+ S+ GL+D E+ ++L+LD +++E+Y + + + P +W+ ++ +L L DG ++ VE+ K +L D + +A YF+ +W + F+F L + S + SQ + + G YN RK+ Q+ R L +EL K F++ +LYNK+KAL + ++ F L N G E L++ ++ VI +++++A EL +LL Y + +PN+R LI+ CD +H+A VP +P +++PG PL T+ P ++ Q S ++ LL K ++ +DL+ G Y+ S+G+++ P+ +I++L+ +K+H+ +TG +GQ+IP+N E +Y++ + ++ + +I T E SYL + ++ + I N + + +TPD VFT+ E L+S ++ + ++ L+ P ++F E + F+ ++ + VL + G V YKIS L + D + ++ S +LL+ ++++Y EKVL+ RPS PV FKLP R L F AK D+ ++ +FR++ + V ++ L +P+ GI++ + + D I+ +E NS + +W D K + D+LT ++++ + +V+ C SDE+GVI++STG L DL +H S + +++ G++A V+V+ N +W +E RKII EFG + VP+ + S + AP +I V ++ CDL L F+ P + +D+ L L+++ E + ++ +S E V +S RS V+ +L + +S + + + E I L + +G VI + F P +D + + N + S I ++++G + + Q F L +I + ++ R+ + +I + ++ ++CV C D TI+VGC DG+V +Y LID K + +P+ + P I+ + RS +K E S A + PI P
Sbjct: 18 LPESPPRVVRIYVSCTPTDMIQERNALMQQVYPKLREYCKEKHGIELQMVDLRWGVLPGIRDDHNQAELFLQELER---CQRVSAGPSFVALIGQRYGDRPLPATIPEHEYEVLRNSLRRNRSRETRDAGMLDHWYFKDTNAIPPVYVLQPISSVISDFNEMNDPEVRKAAQEQWLHTENSLRKLLQKGAELCHKEGSMDGYSKHKYFMGEFENELRHGIENAPRPRDTAFVFMREIEDLKNYVTHKN----------TPKFMDIRWNWKEEKLEIDSDSQRFLYDLKNGKVPAWMGKQNIDKFSILWRFEKVVHPDLHKAYINDFCDKFHDTVIR-LVDKAAFSYTPIPAPPI--FDTVLPHWLITQRKCRDFFGREEIMDRIYAYVTGH-SKQPLVLHGQSGCGKTCVFAKAQEEVPQWVP---DCTTIVRYLGINAESADIRQVIYGVCHQLALLEG----------EDEHHIPTDYKALLKYFFDLLEHYPEDRHLVLFFDSLETLNPEHNAHYLV--WLPEKLNPNVKIVLSTLPEKHDILDRLRTEVIKNPNYFIEV--PPLSVDNCVLLMEYYLQRVGRQISDDQ-LRVVRRAFECCSLPLFVRLTVEEVTRWRSYTKPALKMIVNTIQQAIGVIFDQLEAIHGKTLVSHSLTYLTASATGLSDGEMEDLLSLDDMILDEIY------RTWHPQVRRIPPLVWVRLRADLEPFLFQREVDGVVVSFWNHREFVEAA---KQRYLADEEMCKRIYSEMANYFSCSWHGRPKPFNFSPAVAKSMGLSSTASSADRLVLSQPLTFVGSDGTTRYNKRKYDQMPRTLYLSGRLNELNKMAFFNYLWLYNKSKALSIQHIIATFAL--NPGTESNLVKGALQACQPVILKNMNNMAAELTGRLLTYYASHPNIRHLIQQCDVEGLQHSALVPAFPYHQVPGGPLQHTLESPTPLQ---FFQLLGSDSRYLLAKERSSQNILVFDLATGEWKYDIQASAGDMHLTPDGSMIVLLDHVTEMSVKIHRSDTGKYVGQLIPLNHTT---GETSEKYKLGRMSLSNEFLCIIATFEKSYLCIASVNECKFIEVVNLNGKASVCTITPDSRFVFTNSAETLMSYDLFTLEHVCSLPLEHRPNHVVFTRE-GHRGFVSNLEENVITVLHAKE-GYVDLTYKISLTELL-KGDQISDLVVSH-NEKYLLVRGNSNLVIYGVKNEKVLSCFGRPSDTPVQFKLPQR---SLTDLNFTQAKFSQDDQYVLATIFRNIYIIDVLSGNLVTKLQSPM-GIITSLLLPDKRKQIVTHIE---NSDVIHVWNLDDA---IKHVDTLDRLTGRIQEVLVTKDNTVSFVRCHNSDEVGVIDMSTGQLCDLLTHESPLTGLSITTDGRYAFVSVQPKRPGITNKIWHMEERKIIHEFGEVGG--YSVPLHNVSTIISVCQKEIDFKAPYYISLFKFEEDRVVEVQCDL--------------TLNFVLSKPFVTKEDRYLIVLTADEYNEYKAEYNSPAICAFSLEND---------FAVASYSPADLRSCVNVKRMLDVRPHESNPYAVIVLYSCAAEEDEYSGVSSGYTSGIGFLILDVCSGAVIHVCDTF--FPPDVDLSRILI-NQDVTLCMDAQSHIYDITTGFWKCQLVPTGT---CPQRFALNGKAVIYYEDQEVYVIRVEDGKEIARCDVHMPITCVEVCHDQRTIVVGCSDGAVSAYVLID-----ERYDNAKEIVKTIPSRQLPLSTDIDGRTSRSWDKVESS-------APQTPIRLP 1702
BLAST of AAA domain-containing protein vs. Ensembl Cavefish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 149.058 bits (375), Expect = 1.722e-35 Identity = 213/958 (22.23%), Postives = 399/958 (41.65%), Query Frame = 1
Query: 79 NVINFFVCSS-FEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGL-DSYLETTAAYQQIFYEYLNKHGICDKYNC-PIFL--LGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGN-FLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIV--YAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCSEV-GSQSLVTDLIPKFLPKNLKLIVS----------STDSFDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPC-QTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQEL------------SVILVDVIKDGYLLVDLATTVSVESLIDDKNSHLKDFHQILAGYFNGAWV---DQTISFH-------FDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEES---INNSALVIENDLDS--LAGELIMQLLPYVSYYPNL-RFLIENCDK--VAPKHNAFVPIYPSNKLPGSPLASTIN 2796
N+I C S D ER ++I+P++Q+ C G+ +++D + G+ DS + + E +C K + P FL +G +YG+ P I F+LLL L + EG+ L Q+++ D N V P+ +L I + W T++ L L + +G + E N+ + +KS D+ S VIF R++ +K K +++K + K +DVT D E L + + +++C A +P F + + H+ Y++ F I +++ +G R +L+ +++ +A+L + A F CG + ++ ++ + + + + P+++ GPP SGK+ V R E ++ L + +T + ++ S+ + + + + + R + +L +Q + ++IL + G L +PK +P N+ L+VS S + + YF V T E + + ++ G+ LT EQ + L ++ K T L +++D Q Y ++ +I ++ E +L L+ + GK + H L YI S GL++ E+ ++L+LD V+ EVY N L + ++++FP LW L +Q+L +V ++++K+ YL V+L + H +L+ YF G W + I H D K P +Q ++ + N+RK +L HL+ ++EL + ++ + ++LY KT + V+ ++ DF + EI L+ E + + I+ ++DS L E+ + YP+L L C + VP + PG L +T+N
Sbjct: 2 NIILCVTCKSHLSDLTSERNAFWDKIYPEIQDFC-QSLGLVFEVVDFRWGVSDSVINDHMTVELCLQEI----QLCQKLSVGPSFLALVGSQYGHRPIPRFISENEFELLLSKLSRKDQ----EGSMLLRQWFIKDSNSVPPKYVLQPINVV-----------------SWNLTEARLLQLLCTAALEAEKDGEMSAEQ------NDRVGDGTGFPQKSQDNP-SAVIFVRDLPPLK---------KSEQQKHTL-KFLDVTADGLLDKEAQELLTKLKERIHSAC-----ADDPGFHHIELSKGAIDRKEHKEYLENFCKQIVSQL-KGKISRQTAPPAVPGWLWLQ-QELLHHANLSKKQCAVF-CGRDGLLGKICLVMWESLNMQHGPLVVSGPPGSGKTAVLCRLAQEMRAVLGPQA---VVTLRLLGTSPLSSDVDSVLKSVCVQVCGAFNLAPPCTQTANSHDMLVRFFQSMLHKVSEQGDT-LLLILDSLDHLPHANGGHKL--RWLPKEIPPNIHLVVSTLADWSPCLESLKALNNDDKYFFQV--EPLTLEEGQLITKAYMDKAGRRLTSEQVDAVLQSFQK-TGSPLHLKLLLD-MAKQWTSYTTLSDIRLGSSVQEVISLFLDSLEGKHGKLFVRHALGYITLSRFGLSEAELQDILSLDNDVLAEVYQNR---LPPNHTLLRFPPLLWALFRQDLGDHLVERWENGIAVQFIEIVKERYLSVELRVKM----------------HTVLSEYFLGQWSQGQQKPILLHPLMTQLNADRKVP---------AQPLWFAEG---IPNFRKLHELPFHLLHAGKWEELRQLLLGNLEWLYCKTLSCGVASVIQDFTFCTDVMDCPEIRLIRECFLLLKPTIDFIDGNIDSSLLCTEITARFQALAHAYPDLIGCLYSQCQDWFASCADPVLVPRCSFMEAPGGALKNTLN 867
BLAST of AAA domain-containing protein vs. Ensembl Cavefish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 108.227 bits (269), Expect = 5.705e-23 Identity = 129/561 (22.99%), Postives = 236/561 (42.07%), Query Frame = 1
Query: 1225 PIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCSEV-GSQSLVTDLIPKFLPKNLKLIVS----------STDSFDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPC-QTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDDKNSHLK-----DFHQILAGYFNGAWV---DQTISFH-------FDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEES---INNSALVIENDLDS--LAGELIMQLLPYVSYYPNL-RFLIENCDK--VAPKHNAFVPIYPSNKLPGSPLASTIN 2796
P+++ GPP SGK+ V R E ++ L + +T + ++ S+ + + + + + R + +L +Q + ++IL + G L +PK +P N+ L+VS S + + YF V T E + + ++ G+ LT EQ + L ++ K T L +++D Q Y ++ +I ++ E +L L+ + GK + H L YI S GL++ E+ ++L+LD V+ EVY N L + ++++FP LW L +Q+L LV+ ++G + + +E + K +L H +L+ YF G W + I H D K P +Q ++ + N+RK +L HL+ ++EL + ++ ++LY KT + V+ ++ DF + EI L+ E + + I+ ++DS L E+ + YP+L L C + VP + PG L +T+N
Sbjct: 11 PLVVSGPPGSGKTAVLCRLAQEMRAVLGPQA---VVTLRLLGTSPLSSDVDSVLKSVCVQVCGAFNLAPPCTQTANSHDMLVRFFQSMLHKVSEQGDT-LLLILDSLDHLPHANGGHKL--RWLPKEIPPNIHLVVSTLADWSPCLESLKALNNDDKYFFQV--EPLTLEEGQLITKAYMDKAGRRLTSEQVDAVLQSFQK-TGSPLHLKLLLD-MAKQWTSYTTLSDIRLGSSVQEVISLFLDSLEGKHGKLFVRHALGYITLSRFGLSEAELQDILSLDNDVLAEVYQNR---LPPNHTLLRFPPLLWALFRQDLGDHLVERWENGIAVCGFSLRQFIEIV---KERYLSVELRVKMHTVLSEYFLGQWSQGQQKPILLHPLMTQLNADRKVP---------AQPLWFAEG---IPNFRKLHELPFHLLHAGKWEELRQLLLGSLEWLYCKTLSCGVASVIQDFTFCTDVMDCPEIRLIRECFLLLKPTIDFIDGNIDSSLLCTEITARFQALAHAYPDLIGCLYSQCQDWFASCADPVLVPRCSFMEAPGGALKNTLN 543
BLAST of AAA domain-containing protein vs. Ensembl Cavefish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:103039682]) HSP 1 Score: 87.4261 bits (215), Expect = 1.334e-16 Identity = 81/325 (24.92%), Postives = 142/325 (43.69%), Query Frame = 1
Query: 1933 RFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDV-IKDGYLLV--DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAWV---------------------------DQTISFH---------FDLKNPEMSY--NCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
+ G + L Y+ + GLT+ E+ ++L+LD V+ ++ + S +L +S ++ L +K+EL LV+ +++ L+V + + + L + H +LA YF GAW Q++ H +D + PE + C Q ++ F N+RK +L+ HL D+L+ VI +F +LY K + + L D A KE+ L ++ + + + + SL+ EL +LLP V+ P LR L+ CDK PK+ + VP++ S + SP
Sbjct: 731 KLGSRFVFRALGYVTMARAGLTEVELEDILSLDNSVLGDIMV--SSNL---KSPLRISYDLIAQLKEELEGYLVERQVRNVTLMVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFHCDNNHFASLNISQHRNPHHQQSLHGHDKASADKHSYDRQTPEQPWVFQCNLLDQDIF-------FVNHRKMTELLFHLTRSGRTDDLMYGVIMNFSWLYTMIKIGQFDKALTDIDTAYTYTQEKELKFLASTLRSIKIKVNKNPASLSAELQQRLLPVVTSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSP 1043 HSP 2 Score: 71.2478 bits (173), Expect = 9.721e-12 Identity = 41/155 (26.45%), Postives = 76/155 (49.03%), Query Frame = 1
Query: 46 LPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNF----LEQYYVLDVNCVEPEMIL 498
L +P + F+C++ +D E ER L ++PKL++ C + +GIE +++D+ G+D + Q++ + L + C + L+G+KYG++ P + + F+++L+ AVE LE++Y D N V P L
Sbjct: 105 LALPPQHVPTGRSVRVFICANPDDTEAERNALKEHVYPKLRDFCRENYGIEFQVVDLYWGVDPEEWDSPELQRLRMKLLEECLKTSAGPCFVGLVGEKYGSIRVPGEVESAEFEMILDA--------AVEAGLDTRILEEWYCRDENSVPPAYYL 251
BLAST of AAA domain-containing protein vs. Ensembl Cavefish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:103039682]) HSP 1 Score: 87.4261 bits (215), Expect = 1.446e-16 Identity = 81/325 (24.92%), Postives = 142/325 (43.69%), Query Frame = 1
Query: 1933 RFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDV-IKDGYLLV--DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAWV---------------------------DQTISFH---------FDLKNPEMSY--NCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
+ G + L Y+ + GLT+ E+ ++L+LD V+ ++ + S +L +S ++ L +K+EL LV+ +++ L+V + + + L + H +LA YF GAW Q++ H +D + PE + C Q ++ F N+RK +L+ HL D+L+ VI +F +LY K + + L D A KE+ L ++ + + + + SL+ EL +LLP V+ P LR L+ CDK PK+ + VP++ S + SP
Sbjct: 651 KLGSRFVFRALGYVTMARAGLTEVELEDILSLDNSVLGDIMV--SSNL---KSPLRISYDLIAQLKEELEGYLVERQVRNVTLMVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFHCDNNHFASLNISQHRNPHHQQSLHGHDKASADKHSYDRQTPEQPWVFQCNLLDQDIF-------FVNHRKMTELLFHLTRSGRTDDLMYGVIMNFSWLYTMIKIGQFDKALTDIDTAYTYTQEKELKFLASTLRSIKIKVNKNPASLSAELQQRLLPVVTSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSP 963
BLAST of AAA domain-containing protein vs. Ensembl Cavefish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:103039682]) HSP 1 Score: 87.0409 bits (214), Expect = 1.521e-16 Identity = 81/325 (24.92%), Postives = 142/325 (43.69%), Query Frame = 1
Query: 1933 RFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDV-IKDGYLLV--DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAWV---------------------------DQTISFH---------FDLKNPEMSY--NCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARN--GGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
+ G + L Y+ + GLT+ E+ ++L+LD V+ ++ + S +L +S ++ L +K+EL LV+ +++ L+V + + + L + H +LA YF GAW Q++ H +D + PE + C Q ++ F N+RK +L+ HL D+L+ VI +F +LY K + + L D A KE+ L ++ + + + + SL+ EL +LLP V+ P LR L+ CDK PK+ + VP++ S + SP
Sbjct: 644 KLGSRFVFRALGYVTMARAGLTEVELEDILSLDNSVLGDIMV--SSNL---KSPLRISYDLIAQLKEELEGYLVERQVRNVTLMVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFHCDNNHFASLNISQHRNPHHQQSLHGHDKASADKHSYDRQTPEQPWVFQCNLLDQDIF-------FVNHRKMTELLFHLTRSGRTDDLMYGVIMNFSWLYTMIKIGQFDKALTDIDTAYTYTQEKELKFLASTLRSIKIKVNKNPASLSAELQQRLLPVVTSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSP 956 HSP 2 Score: 71.2478 bits (173), Expect = 1.093e-11 Identity = 40/151 (26.49%), Postives = 75/151 (49.67%), Query Frame = 1
Query: 46 LPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNF----LEQYYVLDVNCVEP 486
L +P + F+C++ +D E ER L ++PKL++ C + +GIE +++D+ G+D + Q++ + L + C + L+G+KYG++ P + + F+++L+ AVE LE++Y D N V P
Sbjct: 28 LALPPQHVPTGRSVRVFICANPDDTEAERNALKEHVYPKLRDFCRENYGIEFQVVDLYWGVDPEEWDSPELQRLRMKLLEECLKTSAGPCFVGLVGEKYGSIRVPGEVESAEFEMILDA--------AVEAGLDTRILEEWYCRDENSVPP 170
BLAST of AAA domain-containing protein vs. Ensembl Nematostella
Match: EDO31117 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYV4]) HSP 1 Score: 156.377 bits (394), Expect = 3.991e-38 Identity = 205/946 (21.67%), Postives = 405/946 (42.81%), Query Frame = 1
Query: 73 ERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQ---IFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYP---DLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRD-DTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVL--------VPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLG----EFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDDKNSHLK-----DFHQILAGYFNGA-WV-DQTISFHFDLKNPEMSYNCCPKSQK-------MYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGK--EIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKL---PGSPLASTIN 2796
E N++ F S+F D ER +L ++P L++ C + +E +++D++ G+ E TA ++ E N + N FL G KYG P +I + F+ L++ + + E + L ++++ + N + E +L + A P D+ ++ + ++EW K + + + + G L E V K + + E I D + + + REI DI I KD+K I D+ + D E L + RQ +++ + ++ + W S+ H Y++ F + DL+ + + L+ + F G ++I+ DYL D+ P+++YG SGK+ + A F + L ++ C F RF+ ++ + L+I + I + E++ ++ E + R +L + + + +++L ++ S + L+ + +PK L ++K+++S + P L VP ++ + + L++ + LT EQ ++ + K + + + + + S ++ +LG E R ++ GK L S L Y+ + GLT+ E+ ++L+LD V+++VY + + +V+ P LW ++ ++ LV+ DG +V E+ + +LK D H ++A +F G W H L + + P + + M++K+ +N RK +L HLV ++ L + V+F+F+++ K KA ++ +L D+ A +I L+++++ S+ I++DL+SLA +LI +LL + +P + L+E + N V I P N PG PL + ++
Sbjct: 20 ESNIVRIFTSSTFTDTFEERNLLMRDVYPSLRKYC-QQHSLEFQVVDMRWGVRD--EATADHKTSDLCIQEIKNCQRLTQGPNYVCFL-GNKYGYRPVPYKINAEEFESLVDIAREVENVKKEEVDLLLEWFLKNENALPAEYVLQPVTAKLPYYNDMREEVHDKYSQQREEWWKISVTFQRVLRISAHVAGRRGKLTEEQVHKYYKSVTEHEIEHGILNCADPEAQTLCYIREIEDINLNI------KDEK----IPLYTDIADGGH-DAEAQEHLFRLKRQRV--LDKLKAENVVQYSVPWNSRGINASDRRHHEYLENF---------------CNRFESDLTR--------LIDRSLECSAFR----GRQEILSRARDYLCRYDSARPLVVYGASGSGKTSIMAVIAFRVKEWLGDNAVCIF--RFLGTSPGTSNTLLTI-KSVCEQIHQVFGLESLKEDVAEDYTELVRHFHELLSTLSVSAERPLVLVLDSVDQLSPSYNAHLM-NWLPKSLSDHIKIVISVLPGYYEILPTLQRSLTDTNCYIEVPTLSRDTGHEILDAWLDSKHRTLTPEQRVLVMAAFDK-----CPQPLFLKLIFAEASEWASYTDVSGVSLGANVPEAIGFLFERLERKHGKMLFSRALQYVTAARSGLTENELEDILSLDDDVIDDVYQYWDPPV---EGVVRLPNLLWARVRSDIDEFLVERQADGKTVVAWYHRQFWEAC---ERMYLKDGVKVDAHALMAEFFLGEFWTWGGGRKKHIVLTRRQKAL---PDADRQVSAQPLMFSKE----IFNLRKLSELPYHLVHSKQFNALSQEVLFNFEWIMAKVKAQSLNSVLADYDTALQAKPDLDIRLVQDTLILSSSNIKHDLNSLAPQLIGRLLAFKGKFPRIASLLEQAYRWIYARNIPV-IAPMNACLISPGGPLITNLH 898
BLAST of AAA domain-containing protein vs. Ensembl Nematostella
Match: EDO37261 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG70]) HSP 1 Score: 80.1073 bits (196), Expect = 4.423e-15 Identity = 143/711 (20.11%), Postives = 287/711 (40.37%), Query Frame = 1
Query: 148 RIFPKLQEQCFDEFGIEIKLIDIKLGL-----DSYLETTAAYQQIFYEYLNKHGICDKYNCP---IFLLGQKYGNV-LPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEP-KFRILW-RDDTGVSEAHHQIYID----QFEAFITAKVVEGVAER-AKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTS---NCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCS-EVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTR-----KPYFLN----VLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFY-----ALN--LNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDG 2172
+++PKL+E C + G E +++D++ G+ D + T ++I C K + I LL +KYG L P+ +P+ +++ H + + L+++Y LD NC+ IL + +++ F + +RK +S R+ +KN IV + K ++ + K +D T D S+L+Q +S +I + ++I W + + H+ Y++ F+ + K+ + ++E + +I + ++ + + C + L + G + ++ ++ DYL + P++L+G GK+ + A + H C + RF+ + + TI + SI QI + LK+ E+ +L S + + +++L ++ S E G++ L D +PK LP + K+IVS+ R K F N + VP ++ + + L +G+ L Q + +S + + + + +++ ++S + P QT Y A+N L R + G+ L+ H L Y+ + GLT+ E+ ++L+ D +V+++V+ + I + P LW+ I+ +L LVD +G
Sbjct: 24 KVYPKLKEFC-KQKGYEFQVVDMRWGVRDVATDLHETTDLCIREI--------RACQKISAGPNFITLLSEKYGYCPLVPV-MPSDELQMI------HANCNSTGKDLLDKWYRLDTNCIPASYILQPVST----------------------------------------------------WIHGFFTEGDKKVRKQAQDDWS-----RDCTALKNAIVTAIHKAHSD-QATVHKYMDTTIGDEI-----TDRMSMLQQLKSSMKQILGINNMLVYKIKWTKKGIDPTNDEHRQYLNTFCRDFQRVLETKITQSISENTSSEIESPIYEEVVQ-HMMFCQSKLDMFH------GRQAVLNSIGDYLREG-LGQPLVLHGCSGCGKTSIMAMAA-KCARDWIHPEAC-VVLRFLGTTPKSSTIRRLMKSICEQIKCVYRLTTSIPQGLKDMVEL-------FPSLLAS--ATAKRPLLVLLDSLDQLSPEDGARLL--DWLPKHLPGHCKMIVSTLPGAQYRCFPKLKAMFKNDKLFISVPSLPHSDVSDILSMWLQQSGRTLQPAQRDLVMSAFSQ-----CPLPLFLKISFDEACRWHSYTD-PGQT--RLYGSVRDAINGLLERIEAKHGRILVQHALGYLTAARSGLTETELDDILSSDDEVLDDVF------QYWTPPIRRLPPLLWVRIRADLDSYLVDRGSEG 620
BLAST of AAA domain-containing protein vs. Ensembl Nematostella
Match: EDO40517 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6Z9]) HSP 1 Score: 66.2402 bits (160), Expect = 8.329e-11 Identity = 100/461 (21.69%), Postives = 190/461 (41.21%), Query Frame = 1
Query: 877 EDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAH--HQIYID----QFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQ-----SNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDS-----FDTRKPYFLN----VLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTL-----GEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLV 2184
++LQS +R + N I+ + I W + E + H Y+ +F + K+ + + +RA D F + +L+ F G EDI+ + Y++ P++LYG GK+ + A T S + E + RF+ + + I L + SA + F T K +P+D + +L FQ + SN+ ++IL ++ + + +P+ LPK++ ++VS+ + K L+ V V + + L+N + LT+ Q + L+ + + + + Y+ + S + L G AL R +R G L+ H L YI + GL++ E+ ++L+ D++V++EV+ + + + P LW I+ EL+ +V+ DG +V
Sbjct: 215 KNLQSEIRSTLDKSN-IFS-----YDIKWTSEGVTPEGNLTHGQYLGKLCTEFYDVMKKKITDAITKRAAGEVRDKEHLFQEVAQHATFCNLKCENFH----GREDILEKIRTYISGSGQK-PLVLYGDSGCGKTSLVAMTAKLVPSWTEY--EPVVVLRFLGTTPDSSNIRLVLR---SACLQLCKAFGTSTKV-------VPQDYQDLLREFQDRLKMAKSNRPIVVILDSADQLTTTDDAHQMV-WLPRKLPKHVYVLVSTLKDPKYACYPALKKLLLDSNCFVEVSSLPSEVACNILTSWLSNDNRRLTDSQRKIVLNAFNR-----CPLPLYLRLAYDHAVTWKSYTPLEKSVLEKNVQGMIKAL-FKRLERRHGTVLVRHALAYITAAKHGLSEPELEDILSCDEEVLDEVF------QYWTPPVRRIPPLLWARIRAELNSYVVECGTDGARVV 639
BLAST of AAA domain-containing protein vs. Ensembl Nematostella
Match: EDO34994 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMT6]) HSP 1 Score: 62.7734 bits (151), Expect = 1.198e-9 Identity = 84/378 (22.22%), Postives = 166/378 (43.92%), Query Frame = 1
Query: 1132 LQINKFAKFGC----GYEDIVYA------MLDY-LTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFV--TSNCTIAEIFL-SIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCS-EVGSQSLVTDLIPKFLPKNLKLIVSST-----DSFDTRKPYFLN---VLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRF----GKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLV 2184
LQ F + C G ED++ + M Y + D N P+++YG GK+ V + + L D+ C + R++ T + ++ + + S+ QI A+ ++ F I + KE++ + R + + + +I+L ++ S E G++ L +P LP ++ L+VS+ + F K + VLVP+ Q + + + L + L+ +Q + + L+ + + V +++ + S + L +N ++R G L+S L Y+ + GLT+ E+ ++L+ D V+++VY + + + P LW+ I+Q+L LV DG +V
Sbjct: 279 LQHLSFCQSKCEQFYGREDVLLSCRLILNMRSYDVLDVCRNRPLVIYGESGCGKTSVVSMVAMRSREWLRGDT-C-VVVRYIGTTPDSSLVRLLVRSVCQQICAVYEKDPSF--IRNDIKELKEDFIRCLRMATV------ERPLLIVLDSLDQLSAEDGARQL--SWLPMTLPDHVHLVVSTIPEVKYECFPVLKAFLPPESFVLVPKLPQKDAAEILVSYLRMEHRTLSTDQQD-IVQQALQEC----SLPIFVRVAFDEAIRWKSYSPLDETVLQHTVRGAINSLFERVERQHGHVLVSRALGYVTAAKSGLTETELEDLLSCDDFVLDDVY------QYWTPPVRRIPPLLWVRIRQDLESYLVTRGADGAQVV 633 HSP 2 Score: 53.1434 bits (126), Expect = 8.878e-7 Identity = 45/146 (30.82%), Postives = 68/146 (46.58%), Query Frame = 1
Query: 79 NVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNC-PIFL--LGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDI 507
V+ F S+F D E ER L + PKL+ C E G E +++D++ G+ E +A L + C + + P F+ LGQKYG P RIP F + L+N R + +E+++ D N V P +L I
Sbjct: 2 KVVRIFTSSTFTDTEAERNALMLKTIPKLKLFC-QEKGYEFQVVDMRWGVR---EQSADDHTTVDLCLKELKACQQLSTGPNFVTFLGQKYGFRPFPPRIPGDEFLQIAAALENEHDR-----SLIEKWFKCDFNGVPPAYMLQPI 138
BLAST of AAA domain-containing protein vs. Ensembl Nematostella
Match: EDO47108 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNA9]) HSP 1 Score: 62.3882 bits (150), Expect = 1.425e-9 Identity = 99/432 (22.92%), Postives = 183/432 (42.36%), Query Frame = 1
Query: 946 KFRILWRD---DTGVSEAHHQIYIDQ----FEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNC-TIAEIFLSIFLQISAI-ILRNNQFETILKNSKEIENNIPRDIEGILLSFQQ-----QSNKKFIIILHDFEKCS-EVGSQSLVTDLIPKFLPKNLKLIVSS--TDSFDTRKPYFLNVL-------VPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKD 2169
+F + W + D SE H Q YI++ F +T + V+ERA+ D A + + C + K F G E+ + ++ L + + +LYG GK+ + A+ C + ++ + F+ I S I L + + + + S E +N+P D++ + F + + K +++L ++ S + G + L D +PK LP N+ L++S+ D ++ P +L VP E + + L + K LT+ Q + L + + + + +++ +P G AL +R + G+ L+SH L YI S GLT+ E+ ++L+LD V+N+VY + I + P LW+ I+ ++S L+D D
Sbjct: 215 QFDVKWAENGIDPSESEEHAQ-YIEELCTSFYETLTGMIGTAVSERAEVEVKDPLAEEVFSHLTFC-----LKKCEAFH-GREEFLDSVKQALLSNGQRI-TVLYGESGCGKTSIMAKI-------------CALVKEWLRKEAVAVVPRFVGISPDSSGIRTLLRSVCQQLCRVSGENADNVPEDMKSLREYFPECLKSAATCKTIVLMLDSLDQLSPDDGGRQL--DWLPKSLPDNIYLVMSTLPGDEYECL-PNLQAILPDACLKEVPSLPLAEADSILTNLLQASRKCLTDSQKQAVLEAFQQCQLPLYLMLAFGEACRWKSYTPEDQITLPPSVKGIINAL-FDRVERVHGRILVSHALGYITASKNGLTEPELEDLLSLDDDVLNDVY------QYWTPPIRRLPPLLWIRIRADISDFLIDRGAD 615 HSP 2 Score: 51.9878 bits (123), Expect = 2.282e-6 Identity = 40/151 (26.49%), Postives = 72/151 (47.68%), Query Frame = 1
Query: 79 NVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGL-----DSYLETTAAYQQIFYEYLNKHGICDKYNC-PIFL--LGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDI 507
++ F S+F D +ER L RI+P++++ C + G E +++D++ G+ D +L + +++ C + + P F+ LGQKYG P +IP F+ LL + N + + L ++ D N V E +L I
Sbjct: 1 KIVRIFTSSTFTDTSVERNTLMERIYPRIKQFC-QQHGYEFQVVDMRWGVRDESTDDHLTSELCMREL--------RACQELSTGPNFITFLGQKYGYRPFPPKIPATEFENLLSAVNNVEDQ-----QLLRHWFRRDDNIVPAEYLLQPI 137
BLAST of AAA domain-containing protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765]) HSP 1 Score: 98.2117 bits (243), Expect = 6.358e-20 Identity = 131/582 (22.51%), Postives = 250/582 (42.96%), Query Frame = 1
Query: 1225 PIILYGPPNSGKSIVFARTIFE----FQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEG---ILLSFQQQS--NKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVLVPEFTQTEFNI-FIQTQLNNTGKLLTEEQNERFLSNYLKFTDG----------ILTASVIVDYFYNQNFIYNSMEEIP----CQTLGE-----FYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDV-IKDGYLLV--DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAWVDQTISF------HFDLKNPEMSYNCCPKSQKMYAKKSGN------------------------VFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGG--KEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
P++++G P +GK+++ + + Q + +++ I RF+ S+ LS L+ L + E I N + + + +P I+ +L++ +S ++ +I+L E+ S+ ++ +P LP+ ++++VS+ + K L L + + IQ ++L ++ L K T G T + V+ Y + + S +++ C T+ E FY++ + G+ + L YI + GLT+ E+ ++L+LD V+ +V + Y ++ ++ L +++EL L++ +++ LLV + + + L + H +LA YF GAW HF N +S++ P Q+ + K S + F N+RK +LV HL D+L+ VI +F +LY K + + L D LA + KE+ L ++ + + + SL+ EL +LLP V+ P LR L+ CDK PK+ + +P++ S + SP
Sbjct: 413 PMVVFGGPCTGKTLLLSEVAKQAYTWLQKEMGPETDPVVIVRFIGSS------QLSTDLRT----LLQSICEQIAINYRCLIHFLPNKIQEMRELLINLLGESSFHRPLVIVLDSLEQLSD-ADEARKLWWLPIQLPRTVRIVVSTLPN----KHGILQKLRHLIHDDGYYVELIQRDRKACSQMLKQQ----LLGVKRKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVE-----NKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDVIV-----ATYLKNPLRISYDLVAKLREELEGYLIERQVRNIALLVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFTYDNNHFTSLN--ISHHKNPHHQQSHEKASSDKYSYDRQTPEQPWVFQCNLLEPDIFFVNHRKMTELVYHLTRSGRTDDLMFGVIMNFSWLYTMIKIGQFEKALTDIDLAYSCSQEKELKFLATTLRGVKVKVLKNPASLSAELQQRLLPVVASLPKLRHLLLECDKDGPKYCSIMPLHSSMDVTYSP 963 HSP 2 Score: 70.8626 bits (172), Expect = 1.484e-11 Identity = 37/144 (25.69%), Postives = 74/144 (51.39%), Query Frame = 1
Query: 67 LPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMIL 498
+P + F+C++ +D E ER L ++PKL++ C + +GIE +++D+ G+D Q++ + L + C + L+G+KYG++ P + + F+++L+ ++ + LE++Y D N V P L
Sbjct: 35 VPSGRSVRVFICANPDDTEAERNALKEHVYPKLRDFCRENYGIEFQVVDLYWGVDPEEWDNPELQRLRMKLLEECLKTSAGPCFVGLVGEKYGSIRVPGEVESAEFEMILDA----AVEAGLDTHILEEWYCRDENSVPPAYYL 174
BLAST of AAA domain-containing protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765]) HSP 1 Score: 98.2117 bits (243), Expect = 6.358e-20 Identity = 131/582 (22.51%), Postives = 250/582 (42.96%), Query Frame = 1
Query: 1225 PIILYGPPNSGKSIVFARTIFE----FQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEG---ILLSFQQQS--NKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVLVPEFTQTEFNI-FIQTQLNNTGKLLTEEQNERFLSNYLKFTDG----------ILTASVIVDYFYNQNFIYNSMEEIP----CQTLGE-----FYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDV-IKDGYLLV--DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAWVDQTISF------HFDLKNPEMSYNCCPKSQKMYAKKSGN------------------------VFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGG--KEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
P++++G P +GK+++ + + Q + +++ I RF+ S+ LS L+ L + E I N + + + +P I+ +L++ +S ++ +I+L E+ S+ ++ +P LP+ ++++VS+ + K L L + + IQ ++L ++ L K T G T + V+ Y + + S +++ C T+ E FY++ + G+ + L YI + GLT+ E+ ++L+LD V+ +V + Y ++ ++ L +++EL L++ +++ LLV + + + L + H +LA YF GAW HF N +S++ P Q+ + K S + F N+RK +LV HL D+L+ VI +F +LY K + + L D LA + KE+ L ++ + + + SL+ EL +LLP V+ P LR L+ CDK PK+ + +P++ S + SP
Sbjct: 413 PMVVFGGPCTGKTLLLSEVAKQAYTWLQKEMGPETDPVVIVRFIGSS------QLSTDLRT----LLQSICEQIAINYRCLIHFLPNKIQEMRELLINLLGESSFHRPLVIVLDSLEQLSD-ADEARKLWWLPIQLPRTVRIVVSTLPN----KHGILQKLRHLIHDDGYYVELIQRDRKACSQMLKQQ----LLGVKRKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVE-----NKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDVIV-----ATYLKNPLRISYDLVAKLREELEGYLIERQVRNIALLVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFTYDNNHFTSLN--ISHHKNPHHQQSHEKASSDKYSYDRQTPEQPWVFQCNLLEPDIFFVNHRKMTELVYHLTRSGRTDDLMFGVIMNFSWLYTMIKIGQFEKALTDIDLAYSCSQEKELKFLATTLRGVKVKVLKNPASLSAELQQRLLPVVASLPKLRHLLLECDKDGPKYCSIMPLHSSMDVTYSP 963 HSP 2 Score: 70.8626 bits (172), Expect = 1.484e-11 Identity = 37/144 (25.69%), Postives = 74/144 (51.39%), Query Frame = 1
Query: 67 LPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMIL 498
+P + F+C++ +D E ER L ++PKL++ C + +GIE +++D+ G+D Q++ + L + C + L+G+KYG++ P + + F+++L+ ++ + LE++Y D N V P L
Sbjct: 35 VPSGRSVRVFICANPDDTEAERNALKEHVYPKLRDFCRENYGIEFQVVDLYWGVDPEEWDNPELQRLRMKLLEECLKTSAGPCFVGLVGEKYGSIRVPGEVESAEFEMILDA----AVEAGLDTHILEEWYCRDENSVPPAYYL 174
BLAST of AAA domain-containing protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765]) HSP 1 Score: 98.2117 bits (243), Expect = 7.525e-20 Identity = 130/580 (22.41%), Postives = 251/580 (43.28%), Query Frame = 1
Query: 1225 PIILYGPPNSGKSIVFARTIFE----FQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEG---ILLSFQQQS--NKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVLVPEFTQTEFNI-FIQTQLNNTGKLLTEEQNERFLSNYLKFTDG----------ILTASVIVDYFYNQNFIYNSMEEIP----CQTLGE-----FYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDV-IKDGYLLV--DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAWVDQTIS-FHFD---LKNPEMSYNCCPKSQKMYAKKSGN------------------------VFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGG--KEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSP 2778
P++++G P +GK+++ + + Q + +++ I RF+ S+ LS L+ L + E I N + + + +P I+ +L++ +S ++ +I+L E+ S+ ++ +P LP+ ++++VS+ + K L L + + IQ ++L ++ L K T G T + V+ Y + + S +++ C T+ E FY++ + G+ + L YI + GLT+ E+ ++L+LD V+ +V + Y ++ ++ L +++EL L++ +++ LLV + + + L + H +LA YF GAW F +D + +S++ P Q+ + K S + F N+RK +LV HL D+L+ VI +F +LY K + + L D LA + KE+ L ++ + + + SL+ EL +LLP V+ P LR L+ CDK PK+ + +P++ S + SP
Sbjct: 403 PMVVFGGPCTGKTLLLSEVAKQAYTWLQKEMGPETDPVVIVRFIGSS------QLSTDLRT----LLQSICEQIAINYRCLIHFLPNKIQEMRELLINLLGESSFHRPLVIVLDSLEQLSD-ADEARKLWWLPIQLPRTVRIVVSTLPN----KHGILQKLRHLIHDDGYYVELIQRDRKACSQMLKQQ----LLGVKRKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVE-----NKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDVIV-----ATYLKNPLRISYDLVAKLREELEGYLIERQVRNIALLVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFTYDNNHFTSLNISHHKNPHHQQSHEKASSDKYSYDRQTPEQPWVFQCNLLEPDIFFVNHRKMTELVYHLTRSGRTDDLMFGVIMNFSWLYTMIKIGQFEKALTDIDLAYSCSQEKELKFLATTLRGVKVKVLKNPASLSAELQQRLLPVVASLPKLRHLLLECDKDGPKYCSIMPLHSSMDVTYSP 953 HSP 2 Score: 70.4774 bits (171), Expect = 1.655e-11 Identity = 37/144 (25.69%), Postives = 74/144 (51.39%), Query Frame = 1
Query: 67 LPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMIL 498
+P + F+C++ +D E ER L ++PKL++ C + +GIE +++D+ G+D Q++ + L + C + L+G+KYG++ P + + F+++L+ ++ + LE++Y D N V P L
Sbjct: 35 VPSGRSVRVFICANPDDTEAERNALKEHVYPKLRDFCRENYGIEFQVVDLYWGVDPEEWDNPELQRLRMKLLEECLKTSAGPCFVGLVGEKYGSIRVPGEVESAEFEMILDA----AVEAGLDTHILEEWYCRDENSVPPAYYL 174
BLAST of AAA domain-containing protein vs. Ensembl Medaka
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 90.1225 bits (222), Expect = 1.849e-17 Identity = 185/883 (20.95%), Postives = 343/883 (38.84%), Query Frame = 1
Query: 193 IEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCP---IFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEG-NFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRI----LWRDDTGVSEAHHQIYID--------QFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYED-------IVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSN----CTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVL-----------VPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVY-INHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVD-----LATTVSVESLIDDKNSHLKDFHQILAGYFNGAWVDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGKEIVLLEESINNSALV-IENDLDSLA------GELIMQLLPYVSYYPNL 2688
+ ++++D+ G+ +Y +I + + +C + + I LLG +YG+ P I K F++ L L EG L ++ D N V P +L I + W+ T++ L L ++ + + G + E + + + + D + ++F RE K ++K + + K +D T A+++++ + Q +L + +++Y S+ + L R H Y+D Q +A I A V E KKI ++ K ++ A A+ G I AM + + + P++++G GK+ + + + E Q L ++ + RF+ ++ + ++ SI LQ+S+ + E++ R+I L Q +I+L E+ +E S IP LP + L+V S DT F+N+ V ++ E +++ L + + LT EQ + L ++ T L +I+ N E++ E + L+R + K L+ L YI + GL + E+ +V++LD V++EVY H + S+++ P LW +K++L L + +G ++ L+ V L ++ H+IL YF G W + + +S P +A N+ RK + L HL+ ++EL + VI YL T VS ++ D + + E + ALV I+ LD L GEL+ +L + +P+L
Sbjct: 16 LPVQVVDLHWGIGNYPFGDHEACEISLQEIK---MCKRLSAGPNFIALLGNRYGHRALPRLISEKQFEVYLSKLSQ-----TPEGIKQLRLWFRKDTNAVPPTYVLQPITDV----------------DSWRFTETQLLQLLRSAASEAEAEGEITAEQKQSFYTSVTAQELEQGLWIG-DHPPNALLFLRENPKQK-------KQKGKEWPKRLAKFMDAT----ANMLLDPESQKLLAELK---SQLYATSQKTTNLHCVELSRGIIDPKRKEHAQYLDSLCQQFISQMKARIEAVVSLRTTESQKKILGNVEEDEDKLSLVLEEAKQHTTMTAELCEGLHGREGILGKICLAMWE--SGQKCHSPLVVHGAAGMGKTALLCKVVREMQRVL--ETRVVLVIRFLAAHHPQRPALDQVLHSICLQVSSACGLVPPTPMTAGSPTELQKFF-RNI----LEEASQQGYTLLIVLDALEQLAEQ-HHSHKLHWIPTNLPPKVHLLV----SMDTCSEAFVNMRLKTDSLENFFEVERLSRDEGERIMESHLRASQRTLTAEQKDVALQSF-TLTGCPLHLKLILSAVQNWTSFTPLTEQLLGNNTEEVMSQLLHRLEHKHRKELVGGALGYIALARDGLLEAELYDVMSLDDDVISEVYRYTHPPT----PSLIRLPPLLWARLKRDLKDHLEERWTNGVAVIAFNHRCLSEVVLGHYLTSERQGRC---HKILGEYFLGRWSGKLKPVALPGLSLLLSDRKVPPQPLWFAPGLANI----RKLQALPHHLLHAGLWEELRQEVI-SMSYLCYGTSVCGVSSVIHDLD---QCSQYMDCTETGLIRDALVLIKPGLDFLDGMSLFYGELLARLSALSAVFPSL 829
BLAST of AAA domain-containing protein vs. Planmine SMEST
Match: SMESG000012845.1 (SMESG000012845.1) HSP 1 Score: 3548.83 bits (9201), Expect = 0.000e+0 Identity = 1738/1751 (99.26%), Postives = 1748/1751 (99.83%), Query Frame = 1
Query: 10 MESFQNLLIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIDQFEAFITAKVVEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDDKNSHLKDFHQILAGYFNGAWVDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSPLASTINCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEVYYGPNRDIILVLETEYRQIIKVHQRETGDLLGQIIPMNWVVLRPFEERNEYRITNIDMNQTKMALIITNEVSYLFVLNLETLEPILAFNPGLRLEMLKLTPDESTVFTHHVERLVSLNVEKNQLNSAVELQGIPLQMLFANEQSKKAFIVCDQQKSVVVLDLESAGVVRKCYKISFENCLDENDYVLEVSCSEIGNPFLLIMSCHSVILYDWNKEKVLNHITRPSQLPVYFKLPNRLDNQPASLKFNAAKLILSDRVIICALFRDVIVCTVSDNKIIKTLHAPVGGIVSEIHIADDYIIGKVEQSQNSAEVMIWKTDPKCLFFKIENNQDKLTRCVKKIQIGGSVAIASCVESDEMGVIEISTGTLVDLYSHSSVVINCCLSSCGKWALVTVKNSHNANILWSLETRKIIFEFGSSTNTEFIVPMKSKSGFYCITNHSKSIDAPNFIVTQILCDLGVEISYTIKVLEISCLGFLTEPPCILNDDKELAFLSSNYRTENGVGTGTNSLILWSRETHTNQNGMSKIITVKEFSEQINRSVEDILSITTTKSMEDVLFIFFKTHDHEIDILHFNCHTGLVIQFMELFDVLPKQMDHKELFLSNNGCYVFYQKTSAIVNLSSGEFIGNISSDANNEYAFQCFVLKDTILILSQKTKLLAYRLPEICKIGQIELKDEVSCVSKCLDDFTIMVGCVDGSVLSYSLIDIFSPYSFLSQIKVVRNFLPTTRSPTIELESIRSLNKTELSQEFDNLIAIKRPISEPIVAHERREFSNIY 5262
MESFQ+LLIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYI+QFEAFITAKVVEGVAERAKKINL+LSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYN NFI NSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLID+KNSHLKDFHQILAGYFNGAWVDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGN+FYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSPLASTINCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEVYYGPNRDIILVLETEYRQIIKVHQRETGDLLGQIIPMNWVVLRPFEERNEYRITNIDMNQT+MALIITNEVSYLFVLNLETLEPILAFNPGLRLEMLKLTPDESTVFTHHVERLVSLNVEKNQLNSAVELQGIPLQMLFANE+SKKAFIVCDQQKSVVVLDLESAGVVRKCYKISFENCLDENDYVLEVSCSEIGNPFLLIMSCHSVILYDWNKEKVLNHITRPSQLPVYFKLPNRLDNQPASLKFNAAKLILSDRVIICALFRDVIVCTVSDNKIIKTLHAPVGGIVSEIHIADDYIIGKVEQSQNSAEVMIWKTDPKCLFFKIENNQDKLTRCVKK+QIGGSVAIASCVESDEMGVIEISTGTLVDLYSHSSVVINCCLSSCGKWALVTVKNSHNANILWSLETRKIIFEFGSSTNTEFIVPMKSKSGF+CITNHSKSIDAPNFIVTQILCDLGVEISYTIKVLEISCLGFLTEPPCILNDDKELAFLSSNYRTENGVGTGTNSLILWSRETHTNQNGMSKIITVKEFSEQINRSVEDILSITTTKSMEDVLFIFFKTHD+EIDILHFNCHTGLVIQFMELFDVLPKQMDHKELFLSNNGCYVFYQKTSAIVNLSSGEFIGNISSDANNEYAFQCFVLKDTILILSQKTKLLAYRLPEICKIGQIELKDEVSCVSKCLDDFTIMVGCVDGSVLSYSLIDIFSPYSFLSQIKVVRNFLPTTRSPTIELE IRSLNKTELSQEFDNLIAIKRPISEPIVAHERREFSNIY
Sbjct: 1 MESFQDLLIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNCPIFLLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQQEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSEAHHQIYIEQFEAFITAKVVEGVAERAKKINLNLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFARTIFEFQSSLPHDSECHFITRFVTSNCTIAEIFLSIFLQISAIILRNNQFETILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKCSEVGSQSLVTDLIPKFLPKNLKLIVSSTDSFDTRKPYFLNVLVPEFTQTEFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNHNFINNSMEEIPCQTLGEFYALNLNRWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLVDLATTVSVESLIDEKNSHLKDFHQILAGYFNGAWVDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNIFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELLDDFQLARNGGKEIVLLEESINNSALVIENDLDSLAGELIMQLLPYVSYYPNLRFLIENCDKVAPKHNAFVPIYPSNKLPGSPLASTINCPEAIESVLVIQNKESMNKELLIKLKNDSRAYFYDLSFGAISYNTLLSSGEVYYGPNRDIILVLETEYRQIIKVHQRETGDLLGQIIPMNWVVLRPFEERNEYRITNIDMNQTRMALIITNEVSYLFVLNLETLEPILAFNPGLRLEMLKLTPDESTVFTHHVERLVSLNVEKNQLNSAVELQGIPLQMLFANEKSKKAFIVCDQQKSVVVLDLESAGVVRKCYKISFENCLDENDYVLEVSCSEIGNPFLLIMSCHSVILYDWNKEKVLNHITRPSQLPVYFKLPNRLDNQPASLKFNAAKLILSDRVIICALFRDVIVCTVSDNKIIKTLHAPVGGIVSEIHIADDYIIGKVEQSQNSAEVMIWKTDPKCLFFKIENNQDKLTRCVKKLQIGGSVAIASCVESDEMGVIEISTGTLVDLYSHSSVVINCCLSSCGKWALVTVKNSHNANILWSLETRKIIFEFGSSTNTEFIVPMKSKSGFFCITNHSKSIDAPNFIVTQILCDLGVEISYTIKVLEISCLGFLTEPPCILNDDKELAFLSSNYRTENGVGTGTNSLILWSRETHTNQNGMSKIITVKEFSEQINRSVEDILSITTTKSMEDVLFIFFKTHDYEIDILHFNCHTGLVIQFMELFDVLPKQMDHKELFLSNNGCYVFYQKTSAIVNLSSGEFIGNISSDANNEYAFQCFVLKDTILILSQKTKLLAYRLPEICKIGQIELKDEVSCVSKCLDDFTIMVGCVDGSVLSYSLIDIFSPYSFLSQIKVVRNFLPTTRSPTIELEPIRSLNKTELSQEFDNLIAIKRPISEPIVAHERREFSNIY 1751
BLAST of AAA domain-containing protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1) HSP 1 Score: 92.8189 bits (229), Expect = 1.943e-18 Identity = 163/764 (21.34%), Postives = 317/764 (41.49%), Query Frame = 1
Query: 25 NLLIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNC-PIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQ--QEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSE--AHHQIYIDQFEAFITAKV----------VEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFAR--TIFE---FQSSLPHDSECH-------------FITRFVTSN---CTIAEIFLSIFLQISAIILRNNQFE--TILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKC---SEVGSQSLVT--DLIPKFLPKNLKLIVS-STDSFDTRKPYFLNVLVPEFTQT----------EFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLN--RWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELS 2142
N ++ + FT + + F+ S+F DF++ER + ++ P L C +++G+ ++L D++ G+ Y + + L + +C K + P F L+G +YG P +P+ F+++ + + ++ F E + +++ DVN P L+ I+ P Y + II + EW K + + + KI +S G E K+ + E F + D F VI ++ + N ++ + K ID N +++ Q++L ++ NS ++ KF + W + G+++ H+ Y+D + + +E + R + L L + + + F +G + +L L D + + PII++G GK+ A+ T+ + F ++ + SE + + RF+ ++ ++ ++ S+ QI +F T L + K + N + + I S+QQ III ++ S ++SL D IP LP + +I+S T++F+++ + EF E + Q+ L + + LT+ Q +S + G+ + ++ Y SMEE + E A+N +++G L+SH L Y+ GLT+ E+ ++L+L V+NEVY H + I++ P + I +LS
Sbjct: 36 NKILSGCINFTDIGVSPPREVRIFLSSTFSDFKVERNLFIKQVIPSLHSIC-NDYGLSLRLCDMRWGVTDYAVNEHLVESLC---LKEIKMCQKTSIGPFFVLLIGNRYGYQPLPSELPSSEFEMIFKIITDN---FPKEAELISKWFQKDVNSEPPVYNLLPIKTFIPK-YGDYEDEIIRRESGHEWWKVEENIRRCLKKSFKIAISQGLFTNEQKRKLIKSVTETEFWTAV---MDDNF--VINKQKASRCLAYERQINGLMNNLQSECAIKYIDYVTRDN-EIICESSAQNLLLEFKNSIKKVELRHFRKFNVPWVSN-GITDLLISHKNYLDDLSTTVICDIKALIVEHMSAIEKHSGRFNNLKLHLQSEVIHHWQFCWQ-----RCFNFYG---RKVQQEILFNLIDRNYDKPIIVHGDSGCGKTAFLAKVSTVIQEKFFNTTGENKSETNENSNGFQLNQTPVIVLRFIGTSMYSSSLHQLLFSVCFQIQLAYKLKVKFRKMTSLSSLKWLFNYLIQQISH--YSYQQSP---LIIIFDSIDQLFMFSNTLNESLSNSLDWIPVPLPPGIHIIISLITENFESKCFQMFQNRLSEFQHKFIHINYFDDKEVVLICQSLLEHKKRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKS--YMSMEECIIKDCVE-SAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYHDPPI---SGIIRLPSLMCSRIHSDLS 765
BLAST of AAA domain-containing protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1) HSP 1 Score: 92.0485 bits (227), Expect = 3.822e-18 Identity = 189/904 (20.91%), Postives = 363/904 (40.15%), Query Frame = 1
Query: 25 NLLIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNC-PIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQ--QEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSE--AHHQIYIDQFEAFITAKV----------VEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFAR--TIFE---FQSSLPHDSECH-------------FITRFVTSN---CTIAEIFLSIFLQISAIILRNNQFE--TILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKC---SEVGSQSLVT--DLIPKFLPKNLKLIVS-STDSFDTRKPYFLNVLVPEFTQT----------EFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLN--RWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLV----------DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAWVDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELL 2532
N ++ + FT + + F+ S+F DF++ER + ++ P L C +++G+ ++L D++ G+ Y + + L + +C K + P F L+G +YG P +P+ F+++ + + ++ F E + +++ DVN P L+ I+ P Y + II + EW K + + + KI +S G E K+ + E F + D F VI ++ + N ++ + K ID N +++ Q++L ++ NS ++ KF + W + G+++ H+ Y+D + + +E + R + L L + + + F +G + +L L D + + PII++G GK+ A+ T+ + F ++ + SE + + RF+ ++ ++ ++ S+ QI +F T L + K + N + + I S+QQ III ++ S ++SL D IP LP + +I+S T++F+++ + EF E + Q+ L + + LT+ Q +S + G+ + ++ Y SMEE + E A+N +++G L+SH L Y+ GLT+ E+ ++L+L V+NEVY H + I++ P + I +LS ++ D + + L V +++ + + D++ I G Q ++KN + N P ++K RK L HLV EL K + +L + K V EL+
Sbjct: 36 NKILSGCINFTDIGVSPPREVRIFLSSTFSDFKVERNLFIKQVIPSLHSIC-NDYGLSLRLCDMRWGVTDYAVNEHLVESL---CLKEIKMCQKTSIGPFFVLLIGNRYGYQPLPSELPSSEFEMIFKIITDN---FPKEAELISKWFQKDVNSEPPVYNLLPIKTFIPK-YGDYEDEIIRRESGHEWWKVEENIRRCLKKSFKIAISQGLFTNEQKRKLIKSVTETEFWTAV---MDDNF--VINKQKASRCLAYERQINGLMNNLQSECAIKYIDYVTRDN-EIICESSAQNLLLEFKNSIKKVELRHFRKFNVPWVSN-GITDLLISHKNYLDDLSTTVICDIKALIVEHMSAIEKHSGRFNNLKLHLQSEVIHHWQFCWQ-----RCFNFYG---RKVQQEILFNLIDRNYDKPIIVHGDSGCGKTAFLAKVSTVIQEKFFNTTGENKSETNENSNGFQLNQTPVIVLRFIGTSMYSSSLHQLLFSVCFQIQLAYKLKVKFRKMTSLSSLKWLFNYLIQQISH--YSYQQSP---LIIIFDSIDQLFMFSNTLNESLSNSLDWIPVPLPPGIHIIISLITENFESKCFQMFQNRLSEFQHKFIHINYFDDKEVVLICQSLLEHKKRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKS--YMSMEECIIKDCVE-SAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYHDPPI---SGIIRLPSLMCSRIHSDLSEYIIKKQTDDKVTLYWYHKQIHQCALKRYVKDLEILEILHKEMADYYAI-CGNIEKTCFLQNHKRKLEIKNADRLINNPPINEK-----------EPRKLHALSFHLVESRQNYELSKLCTANLKFLLSYAKCFGVQELI 893
BLAST of AAA domain-containing protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1) HSP 1 Score: 92.0485 bits (227), Expect = 3.997e-18 Identity = 189/904 (20.91%), Postives = 363/904 (40.15%), Query Frame = 1
Query: 25 NLLIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNC-PIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQ--QEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSE--AHHQIYIDQFEAFITAKV----------VEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFAR--TIFE---FQSSLPHDSECH-------------FITRFVTSN---CTIAEIFLSIFLQISAIILRNNQFE--TILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKC---SEVGSQSLVT--DLIPKFLPKNLKLIVS-STDSFDTRKPYFLNVLVPEFTQT----------EFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLN--RWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELSVILVDVIKDGYLLV----------DLATTVSVESLIDDKNSHLKDFHQILAGYFNGAWVDQTISFHFDLKNPEMSYNCCPKSQKMYAKKSGNVFYNYRKFRQLVRHLVAIDNYDELIKNVIFDFDYLYNKTKALKVSELL 2532
N ++ + FT + + F+ S+F DF++ER + ++ P L C +++G+ ++L D++ G+ Y + + L + +C K + P F L+G +YG P +P+ F+++ + + ++ F E + +++ DVN P L+ I+ P Y + II + EW K + + + KI +S G E K+ + E F + D F VI ++ + N ++ + K ID N +++ Q++L ++ NS ++ KF + W + G+++ H+ Y+D + + +E + R + L L + + + F +G + +L L D + + PII++G GK+ A+ T+ + F ++ + SE + + RF+ ++ ++ ++ S+ QI +F T L + K + N + + I S+QQ III ++ S ++SL D IP LP + +I+S T++F+++ + EF E + Q+ L + + LT+ Q +S + G+ + ++ Y SMEE + E A+N +++G L+SH L Y+ GLT+ E+ ++L+L V+NEVY H + I++ P + I +LS ++ D + + L V +++ + + D++ I G Q ++KN + N P ++K RK L HLV EL K + +L + K V EL+
Sbjct: 36 NKILSGCINFTDIGVSPPREVRIFLSSTFSDFKVERNLFIKQVIPSLHSIC-NDYGLSLRLCDMRWGVTDYAVNEHLVESLC---LKEIKMCQKTSIGPFFVLLIGNRYGYQPLPSELPSSEFEMIFKIITDN---FPKEAELISKWFQKDVNSEPPVYNLLPIKTFIPK-YGDYEDEIIRRESGHEWWKVEENIRRCLKKSFKIAISQGLFTNEQKRKLIKSVTETEFWTAV---MDDNF--VINKQKASRCLAYERQINGLMNNLQSECAIKYIDYVTRDN-EIICESSAQNLLLEFKNSIKKVELRHFRKFNVPWVSN-GITDLLISHKNYLDDLSTTVICDIKALIVEHMSAIEKHSGRFNNLKLHLQSEVIHHWQFCWQ-----RCFNFYG---RKVQQEILFNLIDRNYDKPIIVHGDSGCGKTAFLAKVSTVIQEKFFNTTGENKSETNENSNGFQLNQTPVIVLRFIGTSMYSSSLHQLLFSVCFQIQLAYKLKVKFRKMTSLSSLKWLFNYLIQQISH--YSYQQSP---LIIIFDSIDQLFMFSNTLNESLSNSLDWIPVPLPPGIHIIISLITENFESKCFQMFQNRLSEFQHKFIHINYFDDKEVVLICQSLLEHKKRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKS--YMSMEECIIKDCVE-SAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYHDPPI---SGIIRLPSLMCSRIHSDLSEYIIKKQTDDKVTLYWYHKQIHQCALKRYVKDLEILEILHKEMADYYAI-CGNIEKTCFLQNHKRKLEIKNADRLINNPPINEK-----------EPRKLHALSFHLVESRQNYELSKLCTANLKFLLSYAKCFGVQELI 893
BLAST of AAA domain-containing protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1) HSP 1 Score: 92.0485 bits (227), Expect = 3.998e-18 Identity = 163/764 (21.34%), Postives = 317/764 (41.49%), Query Frame = 1
Query: 25 NLLIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPKLQEQCFDEFGIEIKLIDIKLGLDSYLETTAAYQQIFYEYLNKHGICDKYNC-PIF--LLGQKYGNVLPPLRIPTKIFKLLLETLKNHKKRFAVEGNFLEQYYVLDVNCVEPEMILVDIQAIYPDLYKQDRNSIIICQ--QEWKKTKSILSNLFQNLSKICLSNGTLDVEMVTKIFVNEFEATFSETIRKSFDSKFSPVIFNREIIDIKNFIVISNQKKDDKRKSAIEKLIDVTYSQNADLVINEDLQSVLRQYYNSCNEIYEASEPKFRILWRDDTGVSE--AHHQIYIDQFEAFITAKV----------VEGVAERAKKINLDLSASFLKCYDIICNADLQINKFAKFGCGYEDIVYAMLDYLTDDDTNVPIILYGPPNSGKSIVFAR--TIFE---FQSSLPHDSECH-------------FITRFVTSN---CTIAEIFLSIFLQISAIILRNNQFE--TILKNSKEIENNIPRDIEGILLSFQQQSNKKFIIILHDFEKC---SEVGSQSLVT--DLIPKFLPKNLKLIVS-STDSFDTRKPYFLNVLVPEFTQT----------EFNIFIQTQLNNTGKLLTEEQNERFLSNYLKFTDGILTASVIVDYFYNQNFIYNSMEEIPCQTLGEFYALNLN--RWYKRFGKTLISHCLLYIYCSSGGLTDQEVIEVLNLDKKVMNEVYINHSESLIYDQSIVKFPLSLWLLIKQELS 2142
N ++ + FT + + F+ S+F DF++ER + ++ P L C +++G+ ++L D++ G+ Y + + L + +C K + P F L+G +YG P +P+ F+++ + + ++ F E + +++ DVN P L+ I+ P Y + II + EW K + + + KI +S G E K+ + E F + D F VI ++ + N ++ + K ID N +++ Q++L ++ NS ++ KF + W + G+++ H+ Y+D + + +E + R + L L + + + F +G + +L L D + + PII++G GK+ A+ T+ + F ++ + SE + + RF+ ++ ++ ++ S+ QI +F T L + K + N + + I S+QQ III ++ S ++SL D IP LP + +I+S T++F+++ + EF E + Q+ L + + LT+ Q +S + G+ + ++ Y SMEE + E A+N +++G L+SH L Y+ GLT+ E+ ++L+L V+NEVY H + I++ P + I +LS
Sbjct: 36 NKILSGCINFTDIGVSPPREVRIFLSSTFSDFKVERNLFIKQVIPSLHSIC-NDYGLSLRLCDMRWGVTDYAVNEHLVESLC---LKEIKMCQKTSIGPFFVLLIGNRYGYQPLPSELPSSEFEMIFKIITDN---FPKEAELISKWFQKDVNSEPPVYNLLPIKTFIPK-YGDYEDEIIRRESGHEWWKVEENIRRCLKKSFKIAISQGLFTNEQKRKLIKSVTETEFWTAV---MDDNF--VINKQKASRCLAYERQINGLMNNLQSECAIKYIDYVTRDN-EIICESSAQNLLLEFKNSIKKVELRHFRKFNVPWVSN-GITDLLISHKNYLDDLSTTVICDIKALIVEHMSAIEKHSGRFNNLKLHLQSEVIHHWQFCWQ-----RCFNFYG---RKVQQEILFNLIDRNYDKPIIVHGDSGCGKTAFLAKVSTVIQEKFFNTTGENKSETNENSNGFQLNQTPVIVLRFIGTSMYSSSLHQLLFSVCFQIQLAYKLKVKFRKMTSLSSLKWLFNYLIQQISH--YSYQQSP---LIIIFDSIDQLFMFSNTLNESLSNSLDWIPVPLPPGIHIIISLITENFESKCFQMFQNRLSEFQHKFIHINYFDDKEVVLICQSLLEHKKRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKS--YMSMEECIIKDCVE-SAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYHDPPI---SGIIRLPSLMCSRIHSDLS 765 The following BLAST results are available for this feature:
BLAST of AAA domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of AAA domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of AAA domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of AAA domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of AAA domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 4
BLAST of AAA domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of AAA domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of AAA domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of AAA domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of AAA domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of AAA domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of AAA domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of AAA domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 4
BLAST of AAA domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30003935 ID=SMED30003935|Name=AAA domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=5304bpback to top protein sequence of SMED30003935-orf-1 >SMED30003935-orf-1 ID=SMED30003935-orf-1|Name=SMED30003935-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1752bp MESFQNLLIKTSLPFTAASLPERNVINFFVCSSFEDFEIERKILNNRIFPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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