FMRFamide-activated amiloride-sensitive sodium channel

Query:  128 EFFNNCSIRGVAKVYKSNSXXXXXXXXXXXXXXXXXXXYSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVE--YFQNKGMSPKEFSWKLRKSAKRYLEKDQPHIAESILFYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKLGIGMFFGEVRENCGY-NITRHSSPDFFNCYTINVKPEYSLNT----EYIHLILRFPKPKNLEIFQXXXXXXXXXXXXXGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANF-------RNMSDEDFKEFWKRGRCI-----------SETLTKDKELENMYKNCYKSCIRQKFNLQISNIKWTPTLWQL---EWLFKLQQSWNVLIDFPKNRSIVEKAKADALRFL--NAKDINELISEN-----------ENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLT 1606
            E  +  +  G+AK+  S     K++W + +    T     +  ++R+YL++     ++++      +P+++IC  +P S R +   YF N+  S    +W LR   K   E+D         F + +R +Y+NL  +++  +  N +++ + C             RE C   N +     ++FNC+T N      ++       + LI    K   L     +    +  L+  G +++VH  GS P      I I P     +            P   C      T  + +   +Y +TF  CL   K + ++++C C  + LP   +PS    +C          RN S+ED  +  +    I            + L  D+  E +   C++ C    +   +S   W    +QL   E  FK ++              +EK    + + L  N   +++++S++            + + +++     + LE LS   + +    GL+   L + IGG+  L++G++
Sbjct:   45 ELGSESNAHGLAKIVTSRDTKRKVIWALLVIAGFTAATLQLSLLVRKYLQFQVVELSEIKDSMPVQYPSVSICNIEPISLRTIRRMYFNNE--SQNLITW-LRFIQKFRFEQDS--------FMNSIRAFYENLG-QDAKKLSHNLEDMLMHCRFN----------RELCHVSNFSTFFDGNYFNCFTFNSGQRLQMHATGPENGLSLIFSVEKDDPLPGTYGVYNFDNNILHSAGVRVVVHAPGSMPSPVDHGIDIPPGYSSSVGLKAILHTRLPYPYGNC------TNDMLNGIKQYKYTFFACLQLCKQRLIIQRCGCKSSALPE--VPSYNATFCGVIKDWQEINRNHSNEDHNQSEEDRAFIPTPYLACEEREQKNLNNDRTYE-LSCGCFQPCSETSYLKSVSLSYWPLEFYQLSAVERFFKQERQAGQNHFMKTAYEYLEKLAHPSQKHLARNDSHMDDILSKSYSLSEKEMAKEASDLIRQNMLRLNIYLEDLSVVEYRQLPAYGLA--DLFADIGGTLGLWMGIS 545          

Query:  131 FFNNCSIRGVAKVYKSNSXXXXXXXXXXXXXXXXXXXYSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYFQNK-GMSPKEFSWKLR-------------------------KSAKRYLEKDQPHIAESI------LFYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKLGIGMFFGEVRENCGYNITR---HSSPDFFNCYTINVKPEYSLNTEYIHLILRFPKPKNLEIFQXXXXXXXXXXXXXGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLS-ESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANFRNMSDEDFKEFWKRGRCIS--ETLTKDKELENMYKNCYKSCIRQKFNLQISNIKWTPTLWQLEWLFKLQQSWNVLID--FPKNRSIVEKAKADALRFL---NAKDINELISENENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLT 1606
            F    SIRGV KV+K+ S ++  MW IF+    + L YS+ KI  +YL+Y+  IQT  +++D +PFPA++IC  QPFS  A + + NK  MSP EF+  LR                         K +K + +  Q     S+      L YD+LR+YYQN+  +E+  +G    E  V CI K G     G     C  ++ +    S P+FFNC ++   PEY++    I LI+      + +I  + S L  +     G ++ VHE  + P    + I  EP ++ +I Y    ++   TP + C+S ++   +K  DL  EY++ F+ CL+S   + VL KC C+   LPR+ +P++ +PYC       DE FKE   R +C+   +  T  K  E   K+C+  C+   F  ++S  KW  T W L W+ +L + W+         N S  E++      +L   N  D+  L +    + F  D++++ +V++R SN TF K EK+ L+L  L SR+GG C++Y+GLT
Sbjct:    9 FLETSSIRGVGKVFKTQSPLLSRMWGIFVLGSTSFLFYSVFKITLDYLQYDVNIQTYQEIDDETPFPAVSICNNQPFSVNAYQRWSNKQSMSPTEFNKYLRQQALSLVSPDLMRDKYRDLQAARDRKDSKAFRQIHQSMFDSSVAAMTYSLIYDNLRMYYQNMLADEAMELGHTRNESIVDCIFKYGSIQVLGT--RGCHDDMVKVKTFSDPNFFNCLSVEFTPEYAMTIISITLIVWLGPDDSYDIRHRQSFLNEVYEQAYGLRVDVHEPKTQPRVLEQGIQTEPGKMNEIKYQPIRFERKDTPKNPCISLDAAEKQKFRDLRMEYNYDFELCLNSKVQEVVLNKCGCMYIELPRIAMPNKTHPYCG----FMDEKFKE---RSQCVKSLDMRTIRKSFEG--KDCFPKCVDLSFEKELSTTKWRETKWMLHWIKELCERWDKQFKQLSGSNASEFEESLTGVTDYLTRDNITDLRSLGNSTSKASFDFDDRFSFIVVKRQSNNTFVKTEKIVLTLNALFSRVGGLCSMYIGLT 532          

Query:  131 FFNNCSIRGVAKVYKSNSXXXXXXXXXXXXXXXXXXXYSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYFQNKG-MSPKEFSWKLRKSAKRYLEK---------------DQPHIAESI---LFYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKLG-IGMFFGEVRENCGYNITRHSSPDFFNCYTINVKPEYSLNTEYIHLILRFPKPKNLEIFQXXXXXXXXXXXXXGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANFRN----MSDEDFKEFWKRGRC----ISETLTKDKELENMYKNCYKSCIRQKFNLQISNIKWTPTLWQLEWLFKLQQSWNVLIDFPKNRSIVEKAKADALRFLNAKDINELISE--NENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLTCA 1612
            F  + SIRG  ++ KS ++ ++++W +++ +    L  SI+K++ EY+EY+  IQT + ++  + FPA+T C +QPFS  A E ++ K  MSP  F+  LR  A + LEK               +   I E++   L YD L IYYQ+L + +   +G   K++ V C+ + G   M  G    +    I   S P +FNCY++ +    S +   + LIL     KN     + + L  L    +G ++++HE G      R    + P R+ ++ +       ++ PN  C + S  +++  DLD EY + F+ CL S     V+++C C+ A+ PR+  P+   PYC         + DED     +R +C    IS      K++E   K C + C+  ++  Q+S   W PT WQL W     Q  + L D   N S+          FL  K++    ++  NE + F  D+++A +V++R SN+T  K E L L+   L SRIGG C+LY+G+T A
Sbjct:   30 FLESTSIRGCNRIVKSENRALRVLWTVYVCLTTLFLHISIMKLVNEYMEYSVNIQTYINMDAPTAFPAVTFCNHQPFSSSAYELWKRKKIMSPTTFNQMLRNRASKILEKAIKIPEGPLANIQLINASLIQEALVQGLIYDTLPIYYQSLNWPDHRRLGHKSKDVLVLCLLRYGSTWMLTGPGCADPMLKIRHQSDPKYFNCYSVEIMKYASEHINELGLILWLGPDKNYGKEDRQAFLFDLFEQSVGLRVVIHEPGQRGSLDRHGFQVAPGRMNEVIFQTVKMIHFNRPNKPCFANS--SQRFNDLDEEYDYQFEMCLSSYIQNLVVQRCGCLYAYFPRIYPPNATLPYCGQLVAGEDVLLDEDL--IMRRRQCARLIISNAAVLRKKIEE-EKICLRRCVVTEYETQVSVTMWRPTSWQLYW----SQKTSSLFDSAINGSLTPDEAHLIYHFLKTKNLTNFSADESNEKNTFVFDDRFAYLVVKRKSNDTVVKNENLVLTQNALFSRIGGLCSLYIGMTFA 544          

Query:  122 RKEFFNNCSIRGVAKVYKSNSXXXXXXXXXXXXXXXXXXXYSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYFQ--NKGMSPKEFSWKLRKSAKRYLEKDQPHIAESILFYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKLGIGMFFGEVRENCGYNITRHSSPDFFNCYTIN-VKPEYSLNTEYIHLILRFPKPKNLEIFQXXXXXXXXXXXXXGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKE-YSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLV-IPSEQYPYCANFRNMSDEDFKEFWKRGRCISETLTKDKELENMY-----------KNCYKSCIRQKFNLQISNIKWTPTLWQLEWLFKLQQSWNVLIDFPKN-------RSIVEKAKADALRFLNAKDINELISENENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLTCA 1612
            R+ F ++ S+RGV K+ ++++  ++I+W++F+  M  LL+YS  ++L  Y EY+ ++QT +   D S FPAITIC + PFS RA   +Q  +  ++P  F+ +LR+  ++ L      +A ++LFYD +  YYQNL    +  +G +  E  + C+  +G  +  G+  E C       S P +FNCYT+   + + S     ++LI+          ++  + +  +     G +LL+HE    P      +HIEP ++++I +    WKE   +P D C         I DL N Y +++Q C ++   K  + KCQC+++  PR   +PS Q PYC +FR     +      R RC+ E      ++                 C K C R  ++ ++S  +W  + +QL W+     SW  L +           R+I++   AD L  L      +   +        ++ YA VV+ R S +T  +EEKL ++   L+SR+GG C+LYLGLT A
Sbjct: 1323 RQLFCSSSSLRGVPKICRADTTFLRILWLVFVLAMFILLVYSSTRVLMNYREYDVSVQTSVIGNDPSDFPAITICSHYPFSPRAARMWQQCDGQLAPATFNRRLRQLTRQLLFSGNLRLANTLLFYDKVNTYYQNLDPNVTVSMGHSVDEFLLHCMIAIGNYVMVGKASE-CQLTFQLVSHPKYFNCYTVKPTQADKSQAMSAVYLIVNLGSNSRQHPWE-QAFVMDVFDQAYGLRLLLHEANLYPGIENAGVHIEPGKMVEIAFDTVLWKETQDSPMDRC--HDGWRPAIEDLQNRYRYSYQACKEAHMNKLFIAKCQCLLSRFPRPAGLPSNQIPYCGDFRT---SNISIIESRLRCLEEIGEHQSKMPQPAAAAAAAAVADDSQCRKRCTRYSYDQELSITRWRASSYQLHWMLHQSDSWKRLREVNNESEKRHLLRNILDYLGADNLTRLPVSYQQQERQQQATLTDSAEDTYAYVVVRRKSFDTLKREEKLTVTFEALMSRVGGLCSLYLGLTMA 1835          

Query:  131 FFNNCSIRGVAKVYKSNSXXXXXXXXXXXXXXXXXXXYSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYFQNKG-MSPKEFSWKLRKSAKRYLEKDQPHIAESIL--------FYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKL-GIGMFFGEVRENC---GYNITRHSSPDFFNCYTINVKPEYSLNTEYIHLILRFPKPKNLEIFQXXXXXXXXXXXXXGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANFRNMSDEDFKEFWKRGRCISETLTKDKELENMYK---NCYKSCIRQKFNLQISNIKWTPTLWQLEWLFKLQQSWNVLIDFPKNRSIVEKAKADALRF----------LNAKDINELISENENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLTCA 1612
            F  + SIRG  ++ ++ S  I+++WI FL      L+ S+ +I++EYL Y+  I+T+ +++  + FP++T C +QPFSE+A E +++   +SP +F+  LR+ A+  ++ +  +I+E +L         +D +++YYQNL + +   +G    +    C+ +  G  +  G     C     +I   S P  +NCYT+++    S   + + LI+    P+N +I  + + L+ +     G ++ +HE G      R  I IEP R+ +IN+     +   TP   C+ + K  ++  DLD EY + F+ CLDS   + V+E+C CV A+LPR+VIP+   PYC      +  D +  + R  C+   + +  +L   ++    C + C   +++ ++S   W  T WQL W    Q++ N L +   +     KA  D L             NA D+     +     +   +++  ++++R  N+T  ++E L L+L  LVSRIGG C+LY+G+T A
Sbjct:   33 FLESISIRGCNRIVRAQSMFIRLLWICFLICTTVFLIVSVRRIVKEYLLYSVNIETEERMDAPTEFPSVTFCNHQPFSEKAYELWRSGSVISPTQFNRILRQKAEELVDNNSGNISEHLLQMVAHYSIVFDTIKMYYQNLDWPDQKRLGHQRNQSIYMCLIRFSGEELLLGG--PGCYDEMIHIKERSHPHHYNCYTVDINIYLSRRVQELGLIVWLGPPENYDIRYRQAFLQDVFEQAHGLRVAIHEPGQLVNLDRLGIQIEPGRMNEINFEVIRKEHQQTPRKPCIQDPK--DQYRDLDGEYDYEFELCLDSLIQQIVIERCSCVYAYLPRIVIPNATLPYCGRLLRNNQLDAQGLFDRKECVRHVVQQFAKLRKQFEAEGKCLRRCQTLEYDKRVSVTTWRATQWQLYW---SQETANALEEIMASSPNFTKASVDRLTVYLKTANLSTAFNAPDVTH---KGITRKYGFSDRHTYLLIKRKRNDTVVRKETLVLTLDALVSRIGGLCSLYIGMTFA 542          

Query:  131 FFNNCSIRGVAKVYKSNSXXXXXXXXXXXXXXXXXXXYSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYFQNKG-MSPKEFSWKLRKSAKRYLEKDQPHIAESIL--------FYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKL-GIGMFFGEVRENC---GYNITRHSSPDFFNCYTINVKPEYSLNTEYIHLILRFPKPKNLEIFQXXXXXXXXXXXXXGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANFRNMSDEDFKEFWKRGRCISETLTKDKELENMYK---NCYKSCIRQKFNLQISNIKWTPTLWQLEW-------LFKLQQSWNVLIDFPKNRSIVEKAKADALRFLNAKDINELISENENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLTCAXXXXXXXXXXVLWTEQSHKREIRK 1684
            F  + SIRG  ++ ++ S  I+++WI FL      L+ S+ +I++EYL Y+  ++T+ +++  + FP++T C +QPFSE+A E +++   +SP +F+  LR+ A+  ++ +  +I+E +L         +D +++YYQNL + +   +G    +    C+ +  G  +  G     C     +I   S P  +NCYT+++    S   + + LI+    P+N +I  + + L+ +     G ++ +HE G      R  I IEP R+ +IN+     +   TP   C+ + K   +  DLD EY + F+ CLDS   + V+E+C CV A+LPR+V+P+   PYC      +  D +  + R  C+   + +  +L   ++    C + C   +++ ++S   W  T WQL W       L ++  S         +R IV    A+     NA D+     +     +   +++  ++++R  N+T  ++E L L+L  LVSRIGG C+LY+G+T A FIE++EF  +++ + SH ++ R+
Sbjct:   33 FLESISIRGCNRIVRAQSMFIRLLWICFLICTTVFLIVSVRRIVKEYLLYSVNLETEERMDAPTEFPSVTFCNHQPFSEKAYELWRSGSVISPTQFNRILRQKAEELVDNNSGNISEHLLQMVAHYSIVFDTIKMYYQNLDWPDQKRLGHQRNQSIYMCLIRFSGEELLLGG--PGCYDEMIHIKERSHPHHYNCYTVDINIYLSRRVQELGLIVWLGPPENYDIRYRQAFLQDVFEQAHGLRVAIHEPGQLVNLDRLGIQIEPGRMNEINFEVIRKEHQQTPRKPCIQDPK--NRYRDLDGEYDYEFELCLDSLIQQIVIERCSCVYAYLPRIVVPNATLPYCGRLLRNNQLDAQGLFDRKECVRHVVQQFAKLRKQFEAEGKCLRRCQTLEYDKRVSVTTWRATQWQLYWSQETANALEQIMASSPNFTQTSVDRLIVYLKTANLSTAFNAPDVAH---KGITRKYGFSDRHTYLLIKRKRNDTVVRKETLVLTLDALVSRIGGLCSLYIGMTFAIFIEVIEFFYMVYMKNSHSKKRRR 566          

Query:  242 YSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYFQNKGMSPKEFSWKLRKSAKRYLEKDQPHIAESILFYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKLGIGMFFGEVRENCGYNITRHSSPDFFNCYTINVKPEYSLNTEYIHLILRFPKPKNLEIFQXXXXXXXXXXXXXGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANFRNMSDEDFKEFWKRGRCISETLTKDKELENMYKNCYKSCIRQKFNLQISNIKWTPTLWQLEWLFKLQQSWNVLIDFPKNRSIVEKAKADALRFLNAKDINELISENENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLTCAXXXXXXXXXXVLWTEQSHKREIRKEVEVDKIALNQPPIGPCRDMAIVSEDDFNNIQ 1780
            YSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYFQNKGMSPKEFSWKLRKSAKRYLEKDQPHIAESILFYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKLGIGMFFGEVRENCGYNITRHSSPDFFNCYTINVKPEYSLNTEYIHLILRFPKPKNLEIFQKISLLKSLSLNIIGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANFRNMSDEDFKEFWKRGRCISETLTKDKELENMYKNCYKSCIRQKFNLQISNIKWTPTLWQLEWLFKLQQSWNVLIDFPKNRSIVEKAKADALRFLNAKDINELISENENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLTCAFFIEILEFIIVLWTEQSHKREIRKEVEVDKIALNQPPIGPC DMAIVSEDD NNIQ
Sbjct:    7 YSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYFQNKGMSPKEFSWKLRKSAKRYLEKDQPHIAESILFYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKLGIGMFFGEVRENCGYNITRHSSPDFFNCYTINVKPEYSLNTEYIHLILRFPKPKNLEIFQKISLLKSLSLNIIGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANFRNMSDEDFKEFWKRGRCISETLTKDKELENMYKNCYKSCIRQKFNLQISNIKWTPTLWQLEWLFKLQQSWNVLIDFPKNRSIVEKAKADALRFLNAKDINELISENENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLTCAFFIEILEFIIVLWTEQSHKREIRKEVEVDKIALNQPPIGPCSDMAIVSEDDINNIQ 519          

Query:   95 KIRNSGKFKRKEFFNNCSIRGVAKVYKSNSXXXXXXXXXXXXXXXXXXXYSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYFQNKGMSPKEFSWKLRKSAKRYLEKDQPHIAESILFYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKLGIGMFFGEVRENCGYNITRHSSPDFFNCYTINVKPEYSLNTEYIHLILRFPKPKNLEIFQXXXXXXXXXXXXXGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANFRNMSDEDFKEFWKRGRCISETLTKDKELENMYKNCYKSCIRQKFNLQISNIKWTPTLWQLEWLFKLQQSWNVLIDFPKNRSIVEKAKADALRFLNAKDINELISENENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLTCAXXXXXXXXXXVLWTEQSHKREIRKEVEVDKIALNQPPIGPC 1735
            K R +     + FF NCSIRGVAK YK++S IIK++WIIF+ IMMTLLLYSI+KI+ EYLE+NTTIQT+LQLED+SPFPAITICPYQPFS+RA+ +F+NKGMSPK+FS+KLR++AK +LEKD P  AESILFYDDLR+YYQNLKY +STYIGL++ E+FV+CI KL IGMF G+VR +CG+NI+R+SSPDFFNCYTIN++PEYS +TEY+HLIL+F KP NLE F++ SLLK+L  ++IGAQ+ +HE GSSP ST+EKIH+EPNRLLQINY N  WKE +TP D+C+ ESK  EK+ DLDNEYSF+FQ CLDS KAK +LE+C CVMAFLPR +IPSE++PYCA+F+N+S+E F+ F K+G+CI + L +D+ L +  K CYK C  QKF+LQISNI W P LWQLEWL  L QSWNVLI+ P N +IV  AKA+AL+FLNA ++ +L   +ENS F K+E YACV++ERLSNETFY EE+LGLS+YGLVSRIGGSCTLYLGLTCAFFIEI+E++I+LW  Q            +KI+ N P   PC
Sbjct:    4 KTRGNSVSNMEIFFTNCSIRGVAKAYKTSSLIIKLLWIIFIMIMMTLLLYSIIKIVIEYLEFNTTIQTRLQLEDSSPFPAITICPYQPFSDRAIRFFKNKGMSPKDFSFKLRRTAKSFLEKDSPKKAESILFYDDLRVYYQNLKYNDSTYIGLDESEIFVYCINKLRIGMFIGDVRSDCGFNISRYSSPDFFNCYTINIRPEYSRDTEYVHLILKFFKPTNLERFRETSLLKTLFQHVIGAQITIHETGSSPTSTKEKIHVEPNRLLQINYRNINWKEQNTPTDVCIQESKTLEKLIDLDNEYSFSFQSCLDSYKAKNLLERCHCVMAFLPRSIIPSERFPYCADFKNISEEGFEYFLKKGKCIVKVLNEDQRLTSSDKKCYKKCEEQKFSLQISNIVWEPNLWQLEWLLTLHQSWNVLIEPPANDTIVRSAKAEALKFLNANELKDLTDVHENSPFHKNESYACVIIERLSNETFYNEERLGLSMYGLVSRIGGSCTLYLGLTCAFFIEIIEYLIILWKRQCK----------EKISSNGP--NPC 538          

Query:  131 FFNNCSIRGVAKVYKSNSXXXXXXXXXXXXXXXXXXXYSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYFQNKGMSPKEFSWKLRKSAKRYLEKDQPHIAESILFYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKLGIGMFFGEVRENCGYNITRHSSPDFFNCYTINVKPEYSLNTEYIHLILRFPKPKNLEIFQXXXXXXXXXXXXXGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANFRNMSDEDFKEFWKRGRCISETLTKDKELENMYKNCYKSCIRQKFNLQISNIKWTPTLWQLEWLFKLQQSWNVLIDFPKNRSIVEKAKADALRFLNAKDINELISENENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLTCAXXXXXXXXXXVLW-TEQSHKREIRKE 1687
            FF NCS+RGV+K YKS S IIK++W+IF+ +MM L+LYSI+KIL+EY+EYNTT+Q  LQ EDAS FPAITICP+QPF +R++++F+NKGMSPK+FS KLRK AK +LEK  P  AE+ILFYD+LR YYQNLKY ESTYIGL +KE+FV+CITKL   M  GEV +NCGY I+R+SSPDFFNCYT+N++PEY  NTEYI LILRFPKP NL  + +IS L++LS N IGAQLL+HE GSSP ST+EKIHIEPNR+LQINY N YWKEYSTPND+CLS+ +   KI DL+N Y+FTFQGCL+S  AK++LEKCQC+MAF PR VIPSE++PYCA+F N+++E F+ F     CI + L KD++L +  K C+K C  QKFNLQISNI W P+LWQLEWL+KLQ+SWN+LID P N ++  KAK  A++FL+A  + EL +  +NS+F  DE YACVVLERLSNET+YKEEKLGLS++GL+SRIG SCTLYLGLTCAFFIEILE++I+ W T  + K E+ ++
Sbjct:   15 FFTNCSVRGVSKAYKSRSLIIKLLWLIFITVMMILMLYSIIKILKEYMEYNTTMQNVLQFEDASDFPAITICPHQPFFQRSIKFFKNKGMSPKDFSLKLRKVAKAFLEKQAPDKAENILFYDNLRSYYQNLKYNESTYIGLTEKEIFVYCITKLKHEMLLGEVEKNCGYVISRYSSPDFFNCYTLNMRPEYLKNTEYIQLILRFPKPHNLSQYMEISFLQTLSRNAIGAQLLIHESGSSPTSTKEKIHIEPNRILQINYRNVYWKEYSTPNDVCLSKKENLNKIIDLENNYTFTFQGCLESYIAKKILEKCQCIMAFFPRSVIPSEKFPYCADFHNITEEGFERFVLSTGCIRKVLNKDQKLSSSDKKCFKVCEEQKFNLQISNIYWEPSLWQLEWLYKLQKSWNILIDSPDNLTLANKAKTVAMKFLSATGLAELSTGYDNSLFNNDEMYACVVLERLSNETYYKEEKLGLSMHGLISRIGASCTLYLGLTCAFFIEILEYLILNWMTRNTGKNEVGRD 534          

Query:  116 FKRKEFF----NNCSIRGVAKVYKSNSXXXXXXXXXXXXXXXXXXXYSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYFQN-KGMSPKEFSWKLRKSAKRYLEKDQPHIAESILFYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKLGIGMFFGEVRENCG----YNITRHSSPDFFNCYTIN-VKPEYSLNTEYIHLILRF-PKPKNLEIFQXXXXXXXXXXXXXGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANFRNMSDEDFKEFWKRGRCISETLTKDKELENMYK-NCYKSCIRQKFNLQISNIKWTPTLWQLEWLFKLQQSWNVLIDFPK---NRSIVE-KAKADALRFLNAKDINELISENENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLTCAXXXXXXXXXXVLWTEQSHKREIRKEVEVDKIAL 1711
            F+ K FF    +  SIRG+ K+ K    +  +     L +   L+  S + ++R+++ Y+  I TKL+++  +PFPA+T+C + PFS R    +++ K MSP  F+ K+R      L  +    AE+I +YD + IYYQNL YE++  +G N   +F+ C+  L   ++F E   NC     Y I   S  + FNCYT    +P  S N + + +I+   P+PK+ ++ Q   +         G +++VHE G+ P      +H+EP ++ +I Y  N W+  +TP   C++++     + DL N Y++T   CL  A+ + ++ +C C+  + PR ++P+E  PYC +   + D +    +   +C+S+ L +  + +   K  C+  C    F+  IS  KW  T W L WL +   S   +  F K   NR++ E +A    L + N KD+ +      N    KD+ +A +VL R S ++  K E+L ++ Y LVSRIGG C+L +G+T AF +E++EF  +   +++ KR+ +    V+ + L
Sbjct:   55 FQPKNFFILFCSTISIRGINKIIKGPRPLRLLWLCFVLIMSAILITSSCL-LVRDFMLYDVNINTKLEIDSMTPFPALTVCHHHPFSHRGYRMWKSGKAMSPSYFNRKMRNLTLDQLLLNDVESAETISYYDGISIYYQNLPYEQAIQMGHNS-SIFLTCMYLLENQIYFAE---NCTKLEFYRIKLLSHHEHFNCYTFEPTQPHVSSNLDMLGIIVSLGPEPKHFDMEQSFIIDTFRQAQ--GLKVIVHESGTLPDIDEAGLHVEPGKMNEIIYRPNQWQLTNTPAKPCINDTSRIAYV-DLANTYNYTKHLCLKYAEQEDIMNQCHCMFIYNPRPMMPNESMPYCGSI--LKDFNLSNIYSYVKCLSDVLNQKSKRQQWEKEKCFHRCNYMTFDSTISITKWRATEWHLYWLRQQITSLGEMKQFLKANPNRNVTESQAFKTWLIYGNKKDLRK-TGLKANEFLLKDDNFAYIVLRRESKDSVKKYERLVITQYVLVSRIGGLCSLTVGITLAFIVELVEFCYLFSAKETEKRKRKYSNSVENVKL 591          

Query:  125 KEFFNNCSIRGVAKVYKSNSXXXXXXXXXXXXXXXXXXXYSIVKILREYLEYNTTIQTKLQLEDASPFPAITICPYQPFSERAVEYF-QNKGMSPKEFSWKLRKSAKRYL-----------EKDQPHIAESILFYDDLRIYYQNLKYEESTYIGLNDKELFVFCITKLGIGMFFGEVRENCGYNITRHSSPDFFNCYTINVKPEYSLNTEYIHLILRFPKPKNLEIFQXXXXXXXXXXXXXGAQLLVHERGSSPVSTREKIHIEPNRLLQINYGNNYWKEYSTPNDICLSESKMTEKITDLDNEYSFTFQGCLDSAKAKRVLEKCQCVMAFLPRLVIPSEQYPYCANFRNMSDEDFKEFWKRGRCISETLTKDKELENMY---KNCYKSCIRQKFNLQISNIKWTPTLWQLEWLFKLQQSW----NVL---IDFPKN------RSIVEKAKADALRFLNAKDINELISENENSIFQKDEKYACVVLERLSNETFYKEEKLGLSLYGLVSRIGGSCTLYLGLTCA 1612
            ++FF N SIRG +++ KS +  ++ +WI+F+   +T L+ SI K++ +Y +Y+  IQT +Q+++A+PFPA+T C +QPFSERA + + ++K MSP +F+   R  A +             + D  H        D L +YYQNL    S+ +G N   +   C+   G  M F    ++    +   S P +FNC+T+   P+Y+     + LI+     +   I  +   L  +     G ++++HE  S P    E + IEP RL ++NY      +  T    C++E     +  DLDN + +    C +    +R++ +C+C+  + PR + PS++ PYC     +  E + +   R  CI++   +  ++++     K C  SC   ++    S  KW PT WQL WL ++  +W    N++   I+ P N      R +++   +    F   K+++E I E+E  +F  +E+Y  VV++R +N TF KEE+L LS   LVSR+GG C+LY+GLT A
Sbjct:   18 RKFFANTSIRGFSRIVKSETTFLRTLWILFVVSTITFLIVSIFKVVIDYRQYSVNIQTYIQIDNATPFPALTFCNHQPFSERAYQLWEESKVMSPTQFNELFRSEALKQFKDMVRTKMTPKDSDFNHPLFLTTINDRLSVYYQNLPTTVSSELGHN-ISIIKNCVWSYGQHMAFDNHCQDDMLIVKNISHPSYFNCFTVEPHPKYASIFSRLGLIIWLGPDEQTNIKHRQGFLFDIFEQAYGLRVIIHEPNSYPNIESEGVQIEPGRLNELNYQPELNIKVDTERKPCINEPDRIYR--DLDNVFKYDIDLCFNMELQQRIITECKCIYGYYPRYLHPSKELPYCG---YLEPEKYHDLLFRKNCITKIFNEAPDIKSNLKADKKCIHSCSSIEYTTTTSVTKWRPTDWQLYWLKEVLDAWAQYYNLMARNINIPSNNMTTTDRIMLQNLTSRIETFFTRKNLSEFIPESEKLLF--NERYTFVVVKRKANNTFIKEERLVLSFNALVSRVGGLCSLYIGLTFA 533