SMED30003829

Overview
NameSMED30003829
Smed IDSMED30003829
Length (bp)738
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30003829 (SMED30003829) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30003829 (SMED30003829) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30003829 (SMED30003829) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30003829 (SMED30003829) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003829

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 93

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30003829h1SMcG0020629 Contig2221GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30003829h1SMcG0020573 Contig2221GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30003829h1SMcG0020513 Contig2221GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30003829h1SMcG0020520 Contig2221GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30003829h1SMcG0020450 Contig2221GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30003829h1SMcG0020518 Contig2221GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
Smed sexual biotypeSMED30003829h1SMcG0020629 Contig15760newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30003829h1SMcG0020629 Contig15760uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020629 dd_Smed_v4_1576_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020629 dd_Smed_v4_1576_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020629 dd_Smed_v4_1576_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020517 dd_Smed_v4_1576_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020517 dd_Smed_v4_1576_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020517 dd_Smed_v4_1576_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020515 dd_Smed_v4_1576_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020515 dd_Smed_v4_1576_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020515 dd_Smed_v4_1576_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0016474 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0016474 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0016474 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0016474 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0016474 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020559 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020559 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020559 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020559 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020559 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020515 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020515 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020515 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020515 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020515 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020513 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020513 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020513 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020513 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020513 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020521 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020521 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020521 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020521 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020521 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020629 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020629 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020629 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020629 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020629 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020518 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020518 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020518 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020518 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020518 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020594 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020594 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020594 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020594 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020594 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020517 dd_Smed_v6_1576_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020517 dd_Smed_v6_1576_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020449 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020449 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020449 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020449 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020449 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020629 dd_Smed_v6_1576_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020629 dd_Smed_v6_1576_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020548 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020548 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020548 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020548 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020548 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020515 dd_Smed_v6_1576_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020515 dd_Smed_v6_1576_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020498 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020498 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020498 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020498 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020498 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020450 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020450 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020450 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020450 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020450 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020596 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020596 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020596 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020596 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020596 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30003829h1SMcG0020329 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003829h1SMcG0020329 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30003829h1SMcG0020329 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003829h1SMcG0020329 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003829h1SMcG0020329 dd_Smed_v6_593_1dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30003829 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.000993:12042..12879 -2663
v31.003487:35393..36177 +2654
v31.003259:34220..36128 +2642
v31.001416:76695..77483 +2642
v31.000539:49193..49981 -2621
v31.002025:42989..43768 -2593
v31.001293:10481..11315 +2590
v31.007492:12117..12885 +2566
Homology
[Close]
BLAST of SMED30003829 vs. Ensembl Human
Match: ANK1 (ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492])

HSP 1 Score: 60.8474 bits (146), Expect = 5.390e-10
Identity = 27/64 (42.19%), Postives = 40/64 (62.50%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E ++K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  261 RGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 324
[Close]
BLAST of SMED30003829 vs. Ensembl Human
Match: ANK1 (ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492])

HSP 1 Score: 60.8474 bits (146), Expect = 5.390e-10
Identity = 27/64 (42.19%), Postives = 40/64 (62.50%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E ++K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  261 RGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 324
[Close]
BLAST of SMED30003829 vs. Ensembl Human
Match: ANK1 (ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492])

HSP 1 Score: 60.8474 bits (146), Expect = 5.394e-10
Identity = 27/64 (42.19%), Postives = 40/64 (62.50%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E ++K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  294 RGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 357
[Close]
BLAST of SMED30003829 vs. Ensembl Human
Match: ANK3 (ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494])

HSP 1 Score: 56.225 bits (134), Expect = 1.604e-8
Identity = 22/64 (34.38%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  273 RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLL 336
[Close]
BLAST of SMED30003829 vs. Ensembl Human
Match: ANK3 (ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494])

HSP 1 Score: 55.0694 bits (131), Expect = 4.733e-8
Identity = 22/64 (34.38%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  284 RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLL 347
[Close]
BLAST of SMED30003829 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 47.3654 bits (111), Expect = 6.548e-6
Identity = 21/64 (32.81%), Postives = 36/64 (56.25%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++ LL+ +   I  K KNG +PL +A Q +  D  + L
Sbjct:  282 RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTL 345
[Close]
BLAST of SMED30003829 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 47.3654 bits (111), Expect = 6.548e-6
Identity = 21/64 (32.81%), Postives = 36/64 (56.25%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++ LL+ +   I  K KNG +PL +A Q +  D  + L
Sbjct:  282 RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTL 345
[Close]
BLAST of SMED30003829 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 47.3654 bits (111), Expect = 6.555e-6
Identity = 21/64 (32.81%), Postives = 36/64 (56.25%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++ LL+ +   I  K KNG +PL +A Q +  D  + L
Sbjct:  282 RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTL 345
[Close]
BLAST of SMED30003829 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 47.3654 bits (111), Expect = 6.555e-6
Identity = 21/64 (32.81%), Postives = 36/64 (56.25%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++ LL+ +   I  K KNG +PL +A Q +  D  + L
Sbjct:  282 RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTL 345
[Close]
BLAST of SMED30003829 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 47.3654 bits (111), Expect = 6.562e-6
Identity = 21/64 (32.81%), Postives = 36/64 (56.25%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++ LL+ +   I  K KNG +PL +A Q +  D  + L
Sbjct:  282 RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTL 345
[Close]
BLAST of SMED30003829 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303120)

HSP 1 Score: 55.0694 bits (131), Expect = 2.033e-8
Identity = 21/64 (32.81%), Postives = 37/64 (57.81%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            +  N+E +++  + P+H A+R+GH  ++ +LL     I  K KNG +PL +A Q    D  ++L
Sbjct:  410 KGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARIL 473
[Close]
BLAST of SMED30003829 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0334062)

HSP 1 Score: 54.6842 bits (130), Expect = 2.264e-8
Identity = 21/64 (32.81%), Postives = 37/64 (57.81%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            +  N+E +++  + P+H A+R+GH  ++ +LL     I  K KNG +PL +A Q    D  ++L
Sbjct:  260 KGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARIL 323
[Close]
BLAST of SMED30003829 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303119)

HSP 1 Score: 51.6026 bits (122), Expect = 2.880e-7
Identity = 21/61 (34.43%), Postives = 36/61 (59.02%), Query Frame = 1 
Query:   10 NVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            N+E +++  + P+H A+R+GH  ++ +LL     I  K KNG +PL +A Q    D  ++L
Sbjct:  263 NIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARIL 323
[Close]
BLAST of SMED30003829 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0334061)

HSP 1 Score: 51.6026 bits (122), Expect = 2.926e-7
Identity = 21/61 (34.43%), Postives = 36/61 (59.02%), Query Frame = 1 
Query:   10 NVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            N+E +++  + P+H A+R+GH  ++ +LL     I  K KNG +PL +A Q    D  ++L
Sbjct:  413 NIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARIL 473
[Close]
BLAST of SMED30003829 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303118)

HSP 1 Score: 51.6026 bits (122), Expect = 3.089e-7
Identity = 21/61 (34.43%), Postives = 36/61 (59.02%), Query Frame = 1 
Query:   10 NVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            N+E +++  + P+H A+R+GH  ++ +LL     I  K KNG +PL +A Q    D  ++L
Sbjct:  263 NIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARIL 323
[Close]
BLAST of SMED30003829 vs. Ensembl Zebrafish
Match: ank1a (ankyrin 1, erythrocytic a [Source:ZFIN;Acc:ZDB-GENE-041010-44])

HSP 1 Score: 58.9214 bits (141), Expect = 1.419e-9
Identity = 24/64 (37.50%), Postives = 41/64 (64.06%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  I+++LL +   I  K KNG SP+ +A Q +  DC++ L
Sbjct:  261 RGAKIDAKTKDELTPLHCAARNGHVRIIEILLDQGAPIQAKTKNGLSPIHMAAQGDHLDCIRQL 324
[Close]
BLAST of SMED30003829 vs. Ensembl Zebrafish
Match: ank3b (ankyrin 3b [Source:ZFIN;Acc:ZDB-GENE-060621-2])

HSP 1 Score: 58.151 bits (139), Expect = 1.898e-9
Identity = 24/68 (35.29%), Postives = 40/68 (58.82%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNME 204
            R   ++  +K  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL + E
Sbjct:  261 RGARIDARTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLIHHE 328
[Close]
BLAST of SMED30003829 vs. Ensembl Zebrafish
Match: ank3b (ankyrin 3b [Source:ZFIN;Acc:ZDB-GENE-060621-2])

HSP 1 Score: 58.151 bits (139), Expect = 1.990e-9
Identity = 24/68 (35.29%), Postives = 40/68 (58.82%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNME 204
            R   ++  +K  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL + E
Sbjct:  289 RGARIDARTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLIHHE 356
[Close]
BLAST of SMED30003829 vs. Ensembl Zebrafish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 57.3806 bits (137), Expect = 4.362e-9
Identity = 23/64 (35.94%), Postives = 41/64 (64.06%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  ++++LL +   +  K KNG SP+ +A Q +  DCV+ L
Sbjct:  202 RGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQL 265
[Close]
BLAST of SMED30003829 vs. Ensembl Zebrafish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 57.3806 bits (137), Expect = 4.426e-9
Identity = 23/64 (35.94%), Postives = 41/64 (64.06%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  ++++LL +   +  K KNG SP+ +A Q +  DCV+ L
Sbjct:  294 RGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQL 357
[Close]
BLAST of SMED30003829 vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080])

HSP 1 Score: 56.6102 bits (135), Expect = 1.135e-8
Identity = 26/64 (40.62%), Postives = 38/64 (59.38%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  219 RGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 282
[Close]
BLAST of SMED30003829 vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080])

HSP 1 Score: 56.6102 bits (135), Expect = 1.189e-8
Identity = 26/64 (40.62%), Postives = 38/64 (59.38%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  257 RGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 320
[Close]
BLAST of SMED30003829 vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080])

HSP 1 Score: 56.6102 bits (135), Expect = 1.216e-8
Identity = 26/64 (40.62%), Postives = 38/64 (59.38%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  247 RGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 310
[Close]
BLAST of SMED30003829 vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080])

HSP 1 Score: 56.6102 bits (135), Expect = 1.225e-8
Identity = 26/64 (40.62%), Postives = 38/64 (59.38%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  294 RGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 357
[Close]
BLAST of SMED30003829 vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080])

HSP 1 Score: 56.6102 bits (135), Expect = 1.257e-8
Identity = 26/64 (40.62%), Postives = 38/64 (59.38%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  294 RGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 357
[Close]
BLAST of SMED30003829 vs. Ensembl Mouse
Match: Ank1 (ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88024])

HSP 1 Score: 62.003 bits (149), Expect = 1.425e-10
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  265 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 328
[Close]
BLAST of SMED30003829 vs. Ensembl Mouse
Match: Ank1 (ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88024])

HSP 1 Score: 60.4622 bits (145), Expect = 4.589e-10
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  265 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 328
[Close]
BLAST of SMED30003829 vs. Ensembl Mouse
Match: Ank1 (ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88024])

HSP 1 Score: 60.4622 bits (145), Expect = 4.897e-10
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  294 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 357
[Close]
BLAST of SMED30003829 vs. Ensembl Mouse
Match: Ank1 (ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88024])

HSP 1 Score: 60.4622 bits (145), Expect = 4.924e-10
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  265 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 328
[Close]
BLAST of SMED30003829 vs. Ensembl Mouse
Match: Ank1 (ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88024])

HSP 1 Score: 60.4622 bits (145), Expect = 4.925e-10
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  265 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 328
[Close]
BLAST of SMED30003829 vs. UniProt/SwissProt
Match: sp|P16157|ANK1_HUMAN (Ankyrin-1 OS=Homo sapiens OX=9606 GN=ANK1 PE=1 SV=3)

HSP 1 Score: 60.8474 bits (146), Expect = 2.589e-9
Identity = 27/64 (42.19%), Postives = 40/64 (62.50%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E ++K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  261 RGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 324
[Close]
BLAST of SMED30003829 vs. UniProt/SwissProt
Match: sp|Q02357|ANK1_MOUSE (Ankyrin-1 OS=Mus musculus OX=10090 GN=Ank1 PE=1 SV=2)

HSP 1 Score: 60.4622 bits (145), Expect = 3.447e-9
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  257 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 320
[Close]
BLAST of SMED30003829 vs. UniProt/SwissProt
Match: sp|Q8C8R3|ANK2_MOUSE (Ankyrin-2 OS=Mus musculus OX=10090 GN=Ank2 PE=1 SV=2)

HSP 1 Score: 55.4546 bits (132), Expect = 1.722e-7
Identity = 23/64 (35.94%), Postives = 40/64 (62.50%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H A+R+GH  +++LLL  K  +  + KNG SPL +A Q +  +CVK L
Sbjct:  288 RGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHL 351
[Close]
BLAST of SMED30003829 vs. UniProt/SwissProt
Match: sp|O70511|ANK3_RAT (Ankyrin-3 OS=Rattus norvegicus OX=10116 GN=Ank3 PE=1 SV=3)

HSP 1 Score: 55.0694 bits (131), Expect = 2.288e-7
Identity = 22/64 (34.38%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  298 RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLL 361
[Close]
BLAST of SMED30003829 vs. UniProt/SwissProt
Match: sp|G5E8K5|ANK3_MOUSE (Ankyrin-3 OS=Mus musculus OX=10090 GN=Ank3 PE=1 SV=1)

HSP 1 Score: 55.0694 bits (131), Expect = 2.369e-7
Identity = 22/64 (34.38%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  273 RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLL 336
[Close]
BLAST of SMED30003829 vs. TrEMBL
Match: A0A059LBQ3 (ANK_REP_REGION domain-containing protein (Fragment) OS=Helicosporidium sp. ATCC 50920 OX=1291522 GN=H632_c4503p0 PE=4 SV=1)

HSP 1 Score: 63.5438 bits (153), Expect = 1.864e-8
Identity = 25/66 (37.88%), Postives = 39/66 (59.09%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTN 198
            R     C+ KSK+ P HYA+ +GH ++L+LL  +   +  ++  G+SPL LA    + DCV+ L N
Sbjct:    7 RGAETSCQDKSKLTPAHYAAAHGHEEVLRLLWSKGTDLDAESPGGQSPLHLAAAAGQADCVRFLVN 72
[Close]
BLAST of SMED30003829 vs. TrEMBL
Match: V8NF47 (Ankyrin-1 OS=Ophiophagus hannah OX=8665 GN=ANK1 PE=4 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 4.834e-8
Identity = 28/64 (43.75%), Postives = 40/64 (62.50%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R  N+E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  218 RGANIEVRTKDELTPLHCAARNGHLRIAEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 281
[Close]
BLAST of SMED30003829 vs. TrEMBL
Match: A0A1A8HDW4 (Ankyrin 1, erythrocytic (Fragment) OS=Nothobranchius korthausae OX=1143690 GN=ANK1 PE=4 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 1.215e-7
Identity = 25/64 (39.06%), Postives = 40/64 (62.50%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  I+++LL     I  K KNG SP+ +A Q +  DCV+ L
Sbjct:   95 RGAQIDAKTKDELTPLHCAARNGHVRIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQL 158
[Close]
BLAST of SMED30003829 vs. TrEMBL
Match: A0A2I0TYT3 (Ankyrin-1 isoform x9 OS=Limosa lapponica baueri OX=1758121 GN=llap_10773 PE=4 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 1.357e-7
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  294 RGAQIETRTKDELTPLHCAARNGHVRIAEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 357
[Close]
BLAST of SMED30003829 vs. TrEMBL
Match: A0A4Z2J7F7 (Ankyrin-1 OS=Liparis tanakae OX=230148 GN=Ank1_0 PE=4 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 1.497e-7
Identity = 26/64 (40.62%), Postives = 40/64 (62.50%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A+RNGH+ I+++LL     I  K KNG SP+ +A Q +  DCVK L
Sbjct:  212 RGAQIDAVTKDELTPLHCAARNGHARIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVKQL 275
[Close]
BLAST of SMED30003829 vs. Ensembl Cavefish
Match: ank1a (ankyrin 1, erythrocytic a [Source:ZFIN;Acc:ZDB-GENE-041010-44])

HSP 1 Score: 58.9214 bits (141), Expect = 1.246e-9
Identity = 25/64 (39.06%), Postives = 41/64 (64.06%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  I+++LL +   I  K KNG SP+ +A Q +  DCV+ L
Sbjct:  233 RGATIDAKTKDELTPLHCAARNGHVRIIEILLDQGAPIQAKTKNGLSPIHMAAQGDHMDCVRQL 296
[Close]
BLAST of SMED30003829 vs. Ensembl Cavefish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 58.151 bits (139), Expect = 2.421e-9
Identity = 24/64 (37.50%), Postives = 40/64 (62.50%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A+RNGH  ++++LL +   I  K KNG SP+ +A Q +  DCV+ L
Sbjct:  236 RGAQIDARTKDELTPLHCAARNGHVRVIEILLDQGAPIQAKTKNGLSPIHMAAQGDHMDCVRQL 299
[Close]
BLAST of SMED30003829 vs. Ensembl Cavefish
Match: ank3b (ankyrin 3b [Source:ZFIN;Acc:ZDB-GENE-060621-2])

HSP 1 Score: 56.225 bits (134), Expect = 1.059e-8
Identity = 24/68 (35.29%), Postives = 41/68 (60.29%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNME 204
            R   ++ ++K  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL + E
Sbjct:  237 RGARIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLHHE 304
[Close]
BLAST of SMED30003829 vs. Ensembl Cavefish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1])

HSP 1 Score: 55.4546 bits (132), Expect = 1.907e-8
Identity = 23/64 (35.94%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  292 RGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLL 355
[Close]
BLAST of SMED30003829 vs. Ensembl Cavefish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1])

HSP 1 Score: 55.0694 bits (131), Expect = 2.203e-8
Identity = 23/64 (35.94%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  264 RGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLL 327
[Close]
BLAST of SMED30003829 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 3.196e-9
Identity = 23/64 (35.94%), Postives = 38/64 (59.38%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H A+R+GH  ++++LL     I  K KNG SPL +A Q     CV+LL
Sbjct:  260 RGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLL 323
[Close]
BLAST of SMED30003829 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000093.1 (pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000093.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 3.240e-9
Identity = 23/64 (35.94%), Postives = 38/64 (59.38%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H A+R+GH  ++++LL     I  K KNG SPL +A Q     CV+LL
Sbjct:  267 RGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLL 330
[Close]
BLAST of SMED30003829 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007446.1 (pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007446.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.6026 bits (122), Expect = 6.810e-8
Identity = 21/52 (40.38%), Postives = 35/52 (67.31%), Query Frame = 1 
Query:   37 MRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            + P+H A+R+GH  ++++LL +   I  K KNG SPL +A Q +  +CV++L
Sbjct:    7 LTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVL 58
[Close]
BLAST of SMED30003829 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003991.1 (pep scaffold:Pmarinus_7.0:GL484476:255315:281660:1 gene:ENSPMAG00000003623.1 transcript:ENSPMAT00000003991.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 47.7506 bits (112), Expect = 1.280e-6
Identity = 22/67 (32.84%), Postives = 37/67 (55.22%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNM 201
            +  N+    K   R IH+A+  GH++++K+L+     + CK+K G SPL  A    +   VKLL ++
Sbjct:  160 KGANINAFDKKDRRAIHWAAYMGHTEVVKVLVAHGADVRCKDKKGYSPLHAASSSGQIGVVKLLLDL 226
[Close]
BLAST of SMED30003829 vs. Ensembl Sea Lamprey
Match: asap2a (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a [Source:ZFIN;Acc:ZDB-GENE-041210-256])

HSP 1 Score: 47.7506 bits (112), Expect = 1.311e-6
Identity = 27/69 (39.13%), Postives = 41/69 (59.42%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEK 207
            RN N + E+ +    +H+ SR   ++ LKLLLR K  ++  N+ G++ LD+AKQ +   C  LLT  EK
Sbjct:  548 RNVNKQTENGNTA--LHFCSRYNATECLKLLLRSKAALHVSNEAGETALDIAKQMDHAQCEDLLTLAEK 614
[Close]
BLAST of SMED30003829 vs. Ensembl Nematostella
Match: EDO38657 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCC3])

HSP 1 Score: 45.8246 bits (107), Expect = 7.982e-7
Identity = 22/61 (36.07%), Postives = 34/61 (55.74%), Query Frame = 1 
Query:   10 NVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            N++ +S S +  +HYA+  G  + L+LL+ +  RI   +  G SPLD A +   FDC   L
Sbjct:   20 NIDHQSASGLTALHYAALEGSFECLELLVNKGARIDILDSKGCSPLDFAVRGGNFDCAAYL 80
[Close]
BLAST of SMED30003829 vs. Ensembl Medaka
Match: ank1b (ankyrin-1 [Source:NCBI gene;Acc:101157380])

HSP 1 Score: 59.6918 bits (143), Expect = 8.249e-10
Identity = 25/64 (39.06%), Postives = 40/64 (62.50%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  I+++LL     I  K KNG SP+ +A Q +  DCV+ L
Sbjct:  259 RGAQIDAQTKDELTPLHCAARNGHVRIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQL 322
[Close]
BLAST of SMED30003829 vs. Ensembl Medaka
Match: ENSORLT00000039903.1 (pep primary_assembly:ASM223467v1:15:18469388:18484014:-1 gene:ENSORLG00000030042.1 transcript:ENSORLT00000039903.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.151 bits (139), Expect = 1.650e-9
Identity = 24/64 (37.50%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E ++K  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  266 RGARIEAKTKDGLTPLHCGARSGHEQVVEILLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLL 329
[Close]
BLAST of SMED30003829 vs. Ensembl Medaka
Match: ENSORLT00000040233.1 (pep primary_assembly:ASM223467v1:19:16412534:16434057:1 gene:ENSORLG00000021910.1 transcript:ENSORLT00000040233.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.151 bits (139), Expect = 1.883e-9
Identity = 24/64 (37.50%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  266 RGSKIDARTKDGLTPLHCAARSGHEQVVEMLLNRGAPILSKTKNGLSPLHMATQGDHLNCVQLL 329
[Close]
BLAST of SMED30003829 vs. Ensembl Medaka
Match: ENSORLT00000006308.2 (pep primary_assembly:ASM223467v1:1:12516834:12530692:1 gene:ENSORLG00000005003.2 transcript:ENSORLT00000006308.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.225 bits (134), Expect = 6.860e-9
Identity = 23/64 (35.94%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H A+R+GH   ++LLL     I  + KNG SPL ++ Q +  +CVKLL
Sbjct:  236 RGAQIDAKTRDGLTPLHCAARSGHDPAVELLLERGAPILARTKNGLSPLHMSAQGDHIECVKLL 299
[Close]
BLAST of SMED30003829 vs. Ensembl Medaka
Match: ank1a (ankyrin-1 [Source:NCBI gene;Acc:101174837])

HSP 1 Score: 53.5286 bits (127), Expect = 9.033e-8
Identity = 24/56 (42.86%), Postives = 35/56 (62.50%), Query Frame = 1 
Query:   25 SKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            +  ++ P+H A+RNGH  I+++LL     I  K KNG SP+ +A Q +  DCVK L
Sbjct:  207 ANDELTPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMDCVKQL 262
[Close]
BLAST of SMED30003829 vs. Planmine SMEST
Match: SMESG000010321.1 (SMESG000010321.1)

HSP 1 Score: 233.032 bits (593), Expect = 9.604e-87
Identity = 137/158 (86.71%), Postives = 141/158 (89.24%), Query Frame = 3 
Query:  249 KLFAIIERDDPIEIEKLFISCEFIRENICVNLSGFDWFLIEI*TGLNVLEMAMTSNADKIIKWXXXXXXXXXXXXXXXXXLTAKDKENANLLKECILYLCITRHHMRGFKRFHSAEVINGQRRIVGPTFLEVAVEHGCDLLIDLIMRKTIYDKSSIWI 722
            KLFAIIERDDPIEIEKL+ISCEFIRENI               TGLNVLE+AMTSNADKIIKWILDKSI+ KEIDEVIKELTAKDKENANLLKECILYLCITRHHMRGFKRFHSAEVINGQRRIVGPTFLE+AVEHGCDLLIDLIMRKTIYDK SIWI
Sbjct:  160 KLFAIIERDDPIEIEKLYISCEFIRENIY--------------TGLNVLEIAMTSNADKIIKWILDKSIEKKEIDEVIKELTAKDKENANLLKECILYLCITRHHMRGFKRFHSAEVINGQRRIVGPTFLELAVEHGCDLLIDLIMRKTIYDK-SIWI 302

HSP 2 Score: 106.301 bits (264), Expect = 9.604e-87
Identity = 51/70 (72.86%), Postives = 58/70 (82.86%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKV 210
            RNC +ECE+KS MRPIH AS  G S+I+KL LR KCRI CKNK+GKSPLD+AK  NR DCVKLLTNMEK+
Sbjct:   92 RNCTIECETKSGMRPIHCASWKGDSEIVKLFLRRKCRIDCKNKDGKSPLDIAKDNNRVDCVKLLTNMEKL 161
[Close]
BLAST of SMED30003829 vs. Planmine SMEST
Match: SMESG000019970.1 (SMESG000019970.1)

HSP 1 Score: 221.09 bits (562), Expect = 1.662e-86
Identity = 134/158 (84.81%), Postives = 138/158 (87.34%), Query Frame = 3 
Query:  249 KLFAIIERDDPIEIEKLFISCEFIRENICVNLSGFDWFLIEI*TGLNVLEMAMTSNADKIIKWXXXXXXXXXXXXXXXXXLTAKDKENANLLKECILYLCITRHHMRGFKRFHSAEVINGQRRIVGPTFLEVAVEHGCDLLIDLIMRKTIYDKSSIWI 722
            KLFAIIERD PIEIEKLFISCEFIRENI               TGLNVLEMAMTSNADKIIKWILDKSID KEIDEVIKELTAKDKENANLLKE +LYLCITRHHMRGFKRFHSAEVING RRIVGPT+LE+AVE+GCDLLIDLIMRKTIYDK SIWI
Sbjct:  127 KLFAIIERDAPIEIEKLFISCEFIRENIY--------------TGLNVLEMAMTSNADKIIKWILDKSIDNKEIDEVIKELTAKDKENANLLKERLLYLCITRHHMRGFKRFHSAEVINGHRRIVGPTYLELAVENGCDLLIDLIMRKTIYDK-SIWI 269

HSP 2 Score: 117.087 bits (292), Expect = 1.662e-86
Identity = 55/70 (78.57%), Postives = 61/70 (87.14%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKV 210
            RNCN ECESKSK RPIHYASR GHS+I+KL L+ K RI CKNK+GKSPLD+AKQ NR DCVKLLTNMEK+
Sbjct:   59 RNCNTECESKSKWRPIHYASREGHSEIVKLFLQRKWRIDCKNKDGKSPLDIAKQFNRVDCVKLLTNMEKL 128
[Close]
BLAST of SMED30003829 vs. Planmine SMEST
Match: SMESG000019776.1 (SMESG000019776.1)

HSP 1 Score: 228.794 bits (582), Expect = 4.769e-86
Identity = 136/158 (86.08%), Postives = 140/158 (88.61%), Query Frame = 3 
Query:  249 KLFAIIERDDPIEIEKLFISCEFIRENICVNLSGFDWFLIEI*TGLNVLEMAMTSNADKIIKWXXXXXXXXXXXXXXXXXLTAKDKENANLLKECILYLCITRHHMRGFKRFHSAEVINGQRRIVGPTFLEVAVEHGCDLLIDLIMRKTIYDKSSIWI 722
            KLF+IIERDDPIEIEKLFI C+FIRENI               TGLNVLEMAMTSNADKIIKWILDKSID KEIDEVIKELTAKDKENANLLKECILYLCITRHHMRGFKRFHSAEVINGQRRIVGPTFLE+AVEHGCDLLIDLIMRKTIY+K SIWI
Sbjct:  189 KLFSIIERDDPIEIEKLFICCQFIRENIY--------------TGLNVLEMAMTSNADKIIKWILDKSIDNKEIDEVIKELTAKDKENANLLKECILYLCITRHHMRGFKRFHSAEVINGQRRIVGPTFLELAVEHGCDLLIDLIMRKTIYNK-SIWI 331

HSP 2 Score: 108.227 bits (269), Expect = 4.769e-86
Identity = 50/70 (71.43%), Postives = 60/70 (85.71%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKV 210
            RNCN ECE+K   RPIH+A+  GHS+I+KLLLR KCRI CKNK+GKSPLD+AK+ N FDCV+LLTNMEK+
Sbjct:  121 RNCNTECETKLGERPIHHATWRGHSEIVKLLLRRKCRIDCKNKDGKSPLDIAKEYNHFDCVELLTNMEKL 190

HSP 3 Score: 72.0182 bits (175), Expect = 3.921e-14
Identity = 34/64 (53.12%), Postives = 44/64 (68.75%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            RNCN ECE +S  RPIH+AS NGHS+I+KLLL   C   CK+K+G+ P+  A +    + VKLL
Sbjct:   22 RNCNTECEDESGRRPIHWASSNGHSEIVKLLLDRNCNTECKDKSGERPIHYASRDGNSEIVKLL 85

HSP 4 Score: 64.6994 bits (156), Expect = 9.496e-12
Identity = 33/64 (51.56%), Postives = 42/64 (65.62%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            RNCN EC+ KS  RPIHYASR+G+S+I+KLLL   C   CK+K+   P+  A      + VKLL
Sbjct:   55 RNCNTECKDKSGERPIHYASRDGNSEIVKLLLDRNCNTECKDKSKWRPIHHASSNGNSEIVKLL 118
[Close]
BLAST of SMED30003829 vs. Planmine SMEST
Match: SMESG000019959.1 (SMESG000019959.1)

HSP 1 Score: 223.402 bits (568), Expect = 3.470e-85
Identity = 135/158 (85.44%), Postives = 139/158 (87.97%), Query Frame = 3 
Query:  249 KLFAIIERDDPIEIEKLFISCEFIRENICVNLSGFDWFLIEI*TGLNVLEMAMTSNADKIIKWXXXXXXXXXXXXXXXXXLTAKDKENANLLKECILYLCITRHHMRGFKRFHSAEVINGQRRIVGPTFLEVAVEHGCDLLIDLIMRKTIYDKSSIWI 722
            KLFAIIERDDPIEIEKLFISCEFIRENI               TGLNVLEMAMTSNADKIIKWILDKSID KEIDEVIKELTAKDKENANLLKE +LYLCITRHHMRGFKRFHSAEVINGQRR VGPTFLE+AVE+GCDLLIDLI+RKTIYDK SIWI
Sbjct:  226 KLFAIIERDDPIEIEKLFISCEFIRENIY--------------TGLNVLEMAMTSNADKIIKWILDKSIDNKEIDEVIKELTAKDKENANLLKERLLYLCITRHHMRGFKRFHSAEVINGQRRTVGPTFLELAVENGCDLLIDLILRKTIYDK-SIWI 368

HSP 2 Score: 110.538 bits (275), Expect = 3.470e-85
Identity = 51/70 (72.86%), Postives = 60/70 (85.71%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKV 210
            RNCN ECE++S  RPIHYASR GHS+I+KL L+ KCRI CKNK+GKSPLD AK+ NR DC+KLLTNMEK+
Sbjct:  158 RNCNTECENESGNRPIHYASREGHSEIVKLFLQRKCRIDCKNKDGKSPLDFAKEYNRVDCMKLLTNMEKL 227

HSP 3 Score: 68.1662 bits (165), Expect = 6.689e-13
Identity = 33/64 (51.56%), Postives = 41/64 (64.06%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            RNCN  CE+KS  RPIHYAS  GHS+I+KLLL   C   C+N++G  P+  A      + VKLL
Sbjct:   59 RNCNTICETKSGDRPIHYASWQGHSEIVKLLLDRNCNTECENESGNRPIHYASWQGHSEIVKLL 122
[Close]
BLAST of SMED30003829 vs. Planmine SMEST
Match: SMESG000010347.1 (SMESG000010347.1)

HSP 1 Score: 223.402 bits (568), Expect = 2.687e-84
Identity = 135/158 (85.44%), Postives = 139/158 (87.97%), Query Frame = 3 
Query:  249 KLFAIIERDDPIEIEKLFISCEFIRENICVNLSGFDWFLIEI*TGLNVLEMAMTSNADKIIKWXXXXXXXXXXXXXXXXXLTAKDKENANLLKECILYLCITRHHMRGFKRFHSAEVINGQRRIVGPTFLEVAVEHGCDLLIDLIMRKTIYDKSSIWI 722
            KLFAIIERDDPIEIEKLFISCEFIRENI               TGLNVLEMAMTSNADKIIKWILDKSID KEIDE+IKELTAKDKEN NLLKE ILYLCITRHHMRGFKRFHSAEVINGQRRIVGPT+LE+AVEHGCDLLIDLIMRKTIY+K SIWI
Sbjct:  160 KLFAIIERDDPIEIEKLFISCEFIRENIY--------------TGLNVLEMAMTSNADKIIKWILDKSIDNKEIDEIIKELTAKDKENGNLLKERILYLCITRHHMRGFKRFHSAEVINGQRRIVGPTYLELAVEHGCDLLIDLIMRKTIYNK-SIWI 302

HSP 2 Score: 107.457 bits (267), Expect = 2.687e-84
Identity = 52/70 (74.29%), Postives = 60/70 (85.71%), Query Frame = 1 
Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKV 210
            RNCN+ECE KSK RPIH AS NGHS+ LKLLL+ KCRI  KNK+GKSPLD+AKQ NR DCV+LLT+MEK+
Sbjct:   92 RNCNIECEDKSKWRPIHCASWNGHSETLKLLLQWKCRIDYKNKDGKSPLDIAKQYNRVDCVELLTHMEKL 161
The following BLAST results are available for this feature:
BLAST of SMED30003829 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ANK15.390e-1042.19ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492][more]
ANK15.390e-1042.19ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492][more]
ANK15.394e-1042.19ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492][more]
ANK31.604e-834.38ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494][more]
ANK34.733e-834.38ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494][more]
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BLAST of SMED30003829 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-446.548e-632.81AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-446.548e-632.81AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-446.555e-632.81AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-446.555e-632.81AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-446.562e-632.81AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
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BLAST of SMED30003829 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ank22.033e-832.81gene:FBgn0261788 transcript:FBtr0303120[more]
Ank22.264e-832.81gene:FBgn0261788 transcript:FBtr0334062[more]
Ank22.880e-734.43gene:FBgn0261788 transcript:FBtr0303119[more]
Ank22.926e-734.43gene:FBgn0261788 transcript:FBtr0334061[more]
Ank23.089e-734.43gene:FBgn0261788 transcript:FBtr0303118[more]
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BLAST of SMED30003829 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ank1a1.419e-937.50ankyrin 1, erythrocytic a [Source:ZFIN;Acc:ZDB-GEN... [more]
ank3b1.898e-935.29ankyrin 3b [Source:ZFIN;Acc:ZDB-GENE-060621-2][more]
ank3b1.990e-935.29ankyrin 3b [Source:ZFIN;Acc:ZDB-GENE-060621-2][more]
ank1b4.362e-935.94ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN... [more]
ank1b4.426e-935.94ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of SMED30003829 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ANK11.135e-840.63ankyrin 1 [Source:NCBI gene;Acc:613080][more]
ANK11.189e-840.63ankyrin 1 [Source:NCBI gene;Acc:613080][more]
ANK11.216e-840.63ankyrin 1 [Source:NCBI gene;Acc:613080][more]
ANK11.225e-840.63ankyrin 1 [Source:NCBI gene;Acc:613080][more]
ANK11.257e-840.63ankyrin 1 [Source:NCBI gene;Acc:613080][more]
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BLAST of SMED30003829 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ank11.425e-1042.19ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88... [more]
Ank14.589e-1042.19ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88... [more]
Ank14.897e-1042.19ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88... [more]
Ank14.924e-1042.19ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88... [more]
Ank14.925e-1042.19ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88... [more]
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BLAST of SMED30003829 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P16157|ANK1_HUMAN2.589e-942.19Ankyrin-1 OS=Homo sapiens OX=9606 GN=ANK1 PE=1 SV=... [more]
sp|Q02357|ANK1_MOUSE3.447e-942.19Ankyrin-1 OS=Mus musculus OX=10090 GN=Ank1 PE=1 SV... [more]
sp|Q8C8R3|ANK2_MOUSE1.722e-735.94Ankyrin-2 OS=Mus musculus OX=10090 GN=Ank2 PE=1 SV... [more]
sp|O70511|ANK3_RAT2.288e-734.38Ankyrin-3 OS=Rattus norvegicus OX=10116 GN=Ank3 PE... [more]
sp|G5E8K5|ANK3_MOUSE2.369e-734.38Ankyrin-3 OS=Mus musculus OX=10090 GN=Ank3 PE=1 SV... [more]
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BLAST of SMED30003829 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A059LBQ31.864e-837.88ANK_REP_REGION domain-containing protein (Fragment... [more]
V8NF474.834e-843.75Ankyrin-1 OS=Ophiophagus hannah OX=8665 GN=ANK1 PE... [more]
A0A1A8HDW41.215e-739.06Ankyrin 1, erythrocytic (Fragment) OS=Nothobranchi... [more]
A0A2I0TYT31.357e-742.19Ankyrin-1 isoform x9 OS=Limosa lapponica baueri OX... [more]
A0A4Z2J7F71.497e-740.63Ankyrin-1 OS=Liparis tanakae OX=230148 GN=Ank1_0 P... [more]
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BLAST of SMED30003829 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ank1a1.246e-939.06ankyrin 1, erythrocytic a [Source:ZFIN;Acc:ZDB-GEN... [more]
ank1b2.421e-937.50ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN... [more]
ank3b1.059e-835.29ankyrin 3b [Source:ZFIN;Acc:ZDB-GENE-060621-2][more]
ank3a1.907e-835.94ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1][more]
ank3a2.203e-835.94ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1][more]
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BLAST of SMED30003829 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000000095.13.196e-935.94pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 g... [more]
ENSPMAT00000000093.13.240e-935.94pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 g... [more]
ENSPMAT00000007446.16.810e-840.38pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1... [more]
ENSPMAT00000003991.11.280e-632.84pep scaffold:Pmarinus_7.0:GL484476:255315:281660:1... [more]
asap2a1.311e-639.13ArfGAP with SH3 domain, ankyrin repeat and PH doma... [more]
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BLAST of SMED30003829 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30003829 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO386577.982e-736.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SMED30003829 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ank1b8.249e-1039.06ankyrin-1 [Source:NCBI gene;Acc:101157380][more]
ENSORLT00000039903.11.650e-937.50pep primary_assembly:ASM223467v1:15:18469388:18484... [more]
ENSORLT00000040233.11.883e-937.50pep primary_assembly:ASM223467v1:19:16412534:16434... [more]
ENSORLT00000006308.26.860e-935.94pep primary_assembly:ASM223467v1:1:12516834:125306... [more]
ank1a9.033e-842.86ankyrin-1 [Source:NCBI gene;Acc:101174837][more]
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BLAST of SMED30003829 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000010321.19.604e-8786.71SMESG000010321.1[more]
SMESG000019970.11.662e-8684.81SMESG000019970.1[more]
SMESG000019776.14.769e-8686.08SMESG000019776.1[more]
SMESG000019959.13.470e-8585.44SMESG000019959.1[more]
SMESG000010347.12.687e-8485.44SMESG000010347.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003829 ID=SMED30003829|Name=SMED30003829|organism=Schmidtea mediterranea sexual|type=transcript|length=738bp
CGCAACTGCAATGTCGAATGTGAGAGCAAATCAAAAATGAGACCAATTCA
CTATGCAAGCCGTAATGGTCATTCAGATATATTGAAATTATTGCTGCGGG
AAAAATGTCGAATCTATTGCAAAAACAAAAACGGAAAGAGTCCACTGGAT
TTGGCAAAGCAATGTAATCGGTTTGATTGCGTGAAATTATTGACTAATAT
GGAGAAAGTGTGAATTATTTGCTTATGAATCAATTTGAATAAATATTTAA
GTTATTCGCTATCATTGAACGGGATGATCCAATCGAAATTGAAAAATTGT
TCATATCCTGCGAATTCATTAGAGAGAATATTTGTGTAAATTTGAGTGGT
TTTGATTGGTTTCTAATTGAAATTTAGACTGGATTGAATGTGCTGGAGAT
GGCAATGACGAGTAATGCTGATAAAATCATTAAATGGATTCTTGATAAAT
CTATTGATATTAAAGAAATTGATGAGGTAATTAAAGAGCTGACAGCAAAA
GACAAGGAAAATGCAAATTTATTGAAAGAATGCATTCTTTATCTTTGCAT
CACTCGTCATCACATGAGAGGATTTAAAAGATTCCACTCAGCTGAGGTCA
TCAATGGGCAGCGCAGAATCGTCGGACCAACATTTCTTGAAGTGGCAGTT
GAGCACGGATGTGATTTGCTAATCGATTTGATTATGCGGAAAACCATTTA
TGATAAATCGAGCATTTGGATTTCATTAAAAACTTAAT
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protein sequence of SMED30003829-orf-1

>SMED30003829-orf-1 ID=SMED30003829-orf-1|Name=SMED30003829-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=113bp
MAMTSNADKIIKWILDKSIDIKEIDEVIKELTAKDKENANLLKECILYLC
ITRHHMRGFKRFHSAEVINGQRRIVGPTFLEVAVEHGCDLLIDLIMRKTI
YDKSSIWISLKT*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0000429neoblast
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR020683Ankyrin_rpt-contain_dom
IPR002110Ankyrin_rpt
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0005198structural molecule activity
GO:0005200structural constituent of cytoskeleton
GO:0008093cytoskeletal adaptor activity
GO:0019899enzyme binding
GO:0030507spectrin binding
GO:0051117ATPase binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm
GO:0005829cytosol
GO:0005856cytoskeleton
GO:0005886plasma membrane
GO:0014731spectrin-associated cytoskeleton
GO:0016020membrane
GO:0016323basolateral plasma membrane
GO:0016529sarcoplasmic reticulum
GO:0030018Z disc
GO:0030673axolemma
GO:0031430M band
GO:0031672A band
GO:0042383sarcolemma
GO:0043005neuron projection
GO:0045211postsynaptic membrane
Vocabulary: biological process
TermDefinition
GO:0006887exocytosis
GO:0006888ER to Golgi vesicle-mediated transport
GO:0007010cytoskeleton organization
GO:0007165signal transduction
GO:0010638positive regulation of organelle organization
GO:0045199maintenance of epithelial cell apical/basal polarity
GO:0072661protein targeting to plasma membrane