Serine/threonine-protein kinase 36

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNV--SPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKA-RQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDE-----HSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLD-SKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQIL-----------WSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPK-YCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQ-MIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSL 3894
            M+KYHVLE IGEGSFG+VY+GR+K++ ++VA+KFIPK G+SEK+L NL+REIEIM+ L HPNI+ MLD+FET KEVV VTDYA+GELFQ+LEDDG LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL++  G+KLCDFGFAR MS +T+VLTSIKGTPLYMSPEL++E+PYDHTADLW++GCILYEL VG PPFY  +IF+L+++I+K  ++WP  +S  F++F+QGLL KDP++RL WPD+L+HPF+  HV +   P    + +PFT  L       K+ Q          SRIL +A ++ A+   +   + TGP  +  ++  K     +   ++   P        +L        +L+ S         P    +NR + D  ++      +    V+ + S T++  +E   +EP+SD EWQ + + ++       +   LL + +F  ++ S+       +L+G  +GA  + P  +V+++ ++   D   +  F  +  +P  ++ LL    +    ++Q WY   L DL+  + AYFA     E     ++L ++ + +  F+ LL K+ +Q  D++  LR  S++C   LC+ ++     I+   ++++ +     +D LL  L +        Q    +S+  + Q+ +    I     SA+ A+C+          A+ ++ +++A  L    S +L    +  + +  L L  +++LY C  +S  L + + +    L + F ++ GK+ + D +       +      +++   Q      + +G  VA L   S   S ++AAA L  QL        ++P E + AA   L    +V    P + G  DGLL  +LQL+T   + S+I+ +    +W   W R +  L + E   E + ++  L           W+LISPQG+   L++A+  FT+EP + +  +    ++ ++ ++ L+  +++  +       P+G+  +  ++    QLLCFPF +D+ +D+   +L    D ++  ++       L     E+ + LL  L++     L+Q   TV + P+     L   LL      SD          + A  A++L   P     +  +L G  + Y PL  LL      V A    L+G L +HS  +   L+SQ  +  L+         ++R S++  +GN+ Y    L  ++  ++P +T+LL D    +R N A+ALGN+G     L EE+++ +V   LL  +C D    ++E +L ALRSL
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS------ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPE----VLGQRS-TDVVDLE--NEEPDSDNEWQHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLSSLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFACTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGNSRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAIS----SALAAICTAPVGLPDCWDAKEQVCWHLANQLTED-SSQLRPSLISGLQHPILCLHLLKVLYSCCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEE---STEVTLYFLSLLVFRLQNLPCGMEKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPE---EASAQEGELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQA----PHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALL------SDQPLLTSDLLSLLAHTARVLS--PSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGPEG--LGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL 1260          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNV--SPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKA-RQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDE-----HSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLD-SKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQIL-----------WSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPK-YCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQ-MIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSL 3894
            M+KYHVLE IGEGSFG+VY+GR+K++ ++VA+KFIPK G+SEK+L NL+REIEIM+ L HPNI+ MLD+FET KEVV VTDYA+GELFQ+LEDDG LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL++  G+KLCDFGFAR MS +T+VLTSIKGTPLYMSPEL++E+PYDHTADLW++GCILYEL VG PPFY  +IF+L+++I+K  ++WP  +S  F++F+QGLL KDP++RL WPD+L+HPF+  HV +   P    + +PFT  L       K+ Q          SRIL +A ++ A+   +   + TGP  +  ++  K     +   ++   P        +L        +L+ S         P    +NR + D  ++      +    V+ + S T++  +E   +EP+SD EWQ + + ++       +   LL + +F  ++ S+       +L+G  +GA  + P  +V+++ ++   D   +  F  +  +P  ++ LL    +    ++Q WY   L DL+  + AYFA     E     ++L ++ + +  F+ LL K+ +Q  D++  LR  S++C   LC+ ++     I+   ++++ +     +D LL  L +        Q    +S+  + Q+ +    I     SA+ A+C+          A+ ++ +++A  L    S +L    +  + +  L L  +++LY C  +S  L + + +    L + F ++ GK+ + D +       +      +++   Q      + +G  VA L   S   S ++AAA L  QL        ++P E + AA   L    +V    P + G  DGLL  +LQL+T   + S+I+ +    +W   W R +  L + E   E + ++  L           W+LISPQG+   L++A+  FT+EP + +  +    ++ ++ ++ L+  +++  +       P+G+  +  ++    QLLCFPF +D+ +D+   +L    D ++  ++       L     E+ + LL  L++     L+Q   TV + P+     L   LL      SD          + A  A++L   P     +  +L G  + Y PL  LL      V A    L+G L +HS  +   L+SQ  +  L+         ++R S++  +GN+ Y    L  ++  ++P +T+LL D    +R N A+ALGN+G     L EE+++ +V   LL  +C D    ++E +L ALRSL
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS------ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPE----VLGQRS-TDVVDLE--NEEPDSDNEWQHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLSSLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFACTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGNSRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAIS----SALAAICTAPVGLPDCWDAKEQVCWHLANQLTED-SSQLRPSLISGLQHPILCLHLLKVLYSCCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEE---STEVTLYFLSLLVFRLQNLPCGMEKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPE---EASAQEGELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQA----PHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALL------SDQPLLTSDLLSLLAHTARVLS--PSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGPEG--LGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL 1260          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNV--SPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKA-RQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDE-----HSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLD-SKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQIL-----------WSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPK-YCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQ-MIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSL 3894
            M+KYHVLE IGEGSFG+VY+GR+K++ ++VA+KFIPK G+SEK+L NL+REIEIM+ L HPNI+ MLD+FET KEVV VTDYA+GELFQ+LEDDG LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL++  G+KLCDFGFAR MS +T+VLTSIKGTPLYMSPEL++E+PYDHTADLW++GCILYEL VG PPFY  +IF+L+++I+K  ++WP  +S  F++F+QGLL KDP++RL WPD+L+HPF+  HV +   P    + +PFT  L       K+ Q          SRIL +A ++ A+   +   + TGP  +  ++  K     +   ++   P        +L        +L+ S         P    +NR + D  ++      +    V+ + S T++  +E   +EP+SD EWQ + + ++       +   LL + +F  ++ S+       +L+G  +GA  + P  +V+++ ++   D   +  F  +  +P  ++ LL    +    ++Q WY   L DL+  + AYFA     E     ++L ++ + +  F+ LL K+ +Q  D++  LR  S++C   LC+ ++     I+   ++++ +     +D LL  L +        Q    +S+  + Q+ +    I     SA+ A+C+          A+ ++ +++A  L    S +L    +  + +  L L  +++LY C  +S  L + + +    L + F ++ GK+ + D +       +      +++   Q      + +G  VA L   S   S ++AAA L  QL        ++P E + AA                        LS   +L+T   + S+I+ +    +W   W R +  L + E   E + ++  L           W+LISPQG+   L++A+  FT+EP + +  +    ++ ++ ++ L+  +++  +       P+G+  +  ++    QLLCFPF +D+ +D+   +L    D ++  ++       L     E+ + LL  L++     L+Q   TV + P+     L   LL      SD          + A  A++L   P     +  +L G  + Y PL  LL      V A    L+G L +HS  +   L+SQ  +  L+         ++R S++  +GN+ Y    L  ++  ++P +T+LL D    +R N A+ALGN+G     L EE+++ +V   LL  +C D    ++E +L ALRSL
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS------ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPE----VLGQRS-TDVVDLE--NEEPDSDNEWQHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLSSLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFACTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGNSRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAIS----SALAAICTAPVGLPDCWDAKEQVCWHLANQLTED-SSQLRPSLISGLQHPILCLHLLKVLYSCCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEE---STEVTLYFLSLLVFRLQNLPCGMEKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHA---------------------LSAPAELLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPE---EASAQEGELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQA----PHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALL------SDQPLLTSDLLSLLAHTARVLS--PSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGPEG--LGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL 1239          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNV--SPETLTMNSPFTKPL 891
            M+KYHVLE IGEGSFG+VY+GR+K++ ++VA+KFIPK G+SEK+L NL+REIEIM+ L HPNI+ MLD+FET KEVV VTDYA+GELFQ+LEDDG LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL++  G+KLCDFGFAR MS +T+VLTSIKGTPLYMSPEL++E+PYDHTADLW++GCILYEL VG PPFY  +IF+L+++I+K  ++WP  +S  F++F+QGLL KDP++RL WPD+L+HPF+  HV +   P    + +PFT  L
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRL 277          

Query:   61 PESMDKYHVLEHIGEGSFGKVYRG-RKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDY-ADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLS---QNGVKLCDFGFAREMSI--DTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKG-TIKWPKE--MSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETL 861
            P  +D + + E +G G++  VY+   KK T E+VA+K + K   ++  + NL  EIEI+K + HP+I+Q+ D       +  + ++ A G+L + +     LPE V  +    L SAL +LH   I H D+KPQNILLS   +  +KL DFGFA+ MS   +  VL   +G+PLYM+PE++ ++ YD   DLW++G ILYE   G+PPF + +  EL   I     I+ P    +S D R  +Q LL++DP +R+ + D   HP+V+     S E+L
Sbjct:    8 PPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVL---RGSPLYMAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFAHPWVDLEHMPSGESL 281          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLAN-LKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYAD-GELFQVLEDDGNLPESVVSIIAGHLV----SALFYLHSHRILHRDMKPQNILL-SQNGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVE 831
            S+D + V   +G+G FG V+  R+K T  I+A+K + K    +  +++ LKREIEI   L HPNI+ +   F   K V  + DYA  GELF VL+        V  +IAG  V    +AL Y HS  ++HRD+KP+N+LL S+  +KL DFG++  +  D     ++ GT  Y++PE++  +P+D   D+WA+G +L+E+ VG  PF      +L+  I +  I  P  +++   S I  +++K+P++RL   D++ HP+++
Sbjct:   40 SLDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPG--HKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWS--VVADHSKRHTLCGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGYAPFANQTGDKLIARIKECKIYIPSVVTDGAASLINAIIKKEPQERLPLVDIMAHPWIK 297          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLAN-LKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYAD-GELFQVLEDDGNLPESVVSIIAGHLV----SALFYLHSHRILHRDMKPQNILL-SQNGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVE 831
            S+D + V   +G+G FG V+  R+K T  I+A+K + K    +  +++ LKREIEI   L HPNI+ +   F   K V  + DYA  GELF VL+        V  +IAG  V    +AL Y HS  ++HRD+KP+N+LL S+  +KL DFG++  +  D     ++ GT  Y++PE++  +P+D   D+WA+G +L+E+ VG  PF      +L+  I +  I  P  +++   S I  +++K+P++RL   D++ HP+++
Sbjct:   40 SLDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPG--HKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWS--VVADHSKRHTLCGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGYAPFANQTGDKLIARIKECKIYIPSVVTDGAASLINAIIKKEPQERLPLVDIMAHPWIK 297          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPK---GGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL----QWPDVLHHPF 825
            + + +  L  IG+GSFG+VY+ R K T +I AMK + K     K+E      +R + ++ +  HP ++ +  +F+  +++  V D+ +G ELF  L+ + +  ES     A  +  AL YLH   I++RD+KP+N+LL   G + L DFG  +E    +   ++  GTP Y++PE+I +KPYD T D W LG +LYE+  G PPFY+ +  E+ + II   ++    +S      I GLLQKD  KRL     + D+  HPF
Sbjct:  121 TANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNV-LINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLLQKDRSKRLGHRNDFRDIRDHPF 381          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPK---GGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL----QWPDVLHHPF 825
            + + +  L  IG+GSFG+VY+ R K T +I AMK + K     K+E      +R + ++ +  HP ++ +  +F+  +++  V D+ +G ELF  L+ + +  ES     A  +  AL YLH   I++RD+KP+N+LL   G + L DFG  +E    +   ++  GTP Y++PE+I +KPYD T D W LG +LYE+  G PPFY+ +  E+ + II   ++    +S      I GLLQKD  KRL     + D+  HPF
Sbjct:  131 TANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNV-LINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLLQKDRSKRLGHRNDFRDIRDHPF 391          

Query:   79 YHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDY-ADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYD-HTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPE 855
            Y + + +G+G  G V  G    TG  VA+K + K   SE  L  ++REI IMK + HP+++ + D +E  K +  + ++ + GELF  L   G L           ++SAL + H+H I HRD+KP+N+LL + N +K+ DFG A  + ++  +L +  G+P Y  PE+I+ + YD   AD+W+ G ILY L VG  PF  +N+  L+  + +G    P  +  D +S ++ +++ DP KR    DV  HP+V       PE
Sbjct:   47 YKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKLSESVLQKVEREIAIMKLIEHPHVLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHAHNICHRDLKPENLLLDERNNIKVADFGMA-SLQVEGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRNLLEKVKRGVFHIPHFVPADVQSLLRAMIEVDPGKRYSLADVFKHPWVSGTTKADPE 307          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQN-GVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPET---LTMNSPFTKP 888
            M++Y V   +G+GSFG VY+  +K   ++VA+K I K G++ K+L NL+RE +I   L HP++I+M+++FE+  ++  VT++A  +L + L  +G + E     + GHLVSAL+YLHS+RILHRD+KPQN+LL +N   KLCDFG AR M++ T VLTSIKGTPLYM+PEL+ E+PYDH AD+W+LGCI YE   G+PPF  ++I  L+ +I    +KWP  ++ + RSF+QGLL+KDP  R+ W  +L HPFVE  + ++ ET       SPFT P
Sbjct:    1 MNRYAVSSMVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATKELKNLRRECDIQARLKHPHVIEMIESFESKTDLFVVTEFALMDLHRYLSYNGAMGEEPARRVTGHLVSALYYLHSNRILHRDLKPQNVLLDKNMHAKLCDFGLARNMTLGTHVLTSIKGTPLYMAPELLAEQPYDHHADMWSLGCIAYESMAGQPPFCASSILHLVKMIKHEDVKWPSTLTSECRSFLQGLLEKDPGLRISWTQLLCHPFVEGRIFIA-ETQAEAAKESPFTNP 276          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSE-KDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDY-ADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL 795
            +D Y +++ +G G+FG+V   R + + +  AMK +        K + ++K E  I++ + HP +I +  + +    +  + DY   GELF  L + G       +  A  +VSAL YLHS +I++RD+KP+N+L++++G +K+ DFGFA+++   T  L    GTP Y++PE+IQ K ++   D WALG ++YE+ VG PPFY    F +   I+ G I+W + M    +  I+ LL  D  KRL
Sbjct:  188 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLC---GTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRL 429          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQW-----PDVLHHPFVESHVNVSPETLTMNSPFTKPLSAS----QYAEKE 918
            +++ +  L+ +G+G+FGKV   R+K T ++ A+K + K    +KD +A+   E  ++KS NHP +I +  +F+T   +  V  Y +G ELF  L  +    E         ++SAL YLHS  I++RD+K +N+LL ++G +K+ DFG  +E         +  GTP Y++PE++ +  Y    D W  G ++YE+  GR PFY  +   L  +I+   +K+P+ ++++ ++ + GLL KDPKKRL        ++  HPF  S +N +   L    P  KP   S    +Y +KE
Sbjct:  181 TLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFAS-INWTDLVLKKIPPPFKPQVTSDTDTRYFDKE 475          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQW-----PDVLHHPFVESHVNVSPETLTMNSPFTKPLSAS----QYAEKE 918
            +++ +  L+ +G+G+FGKV   R+K T ++ A+K + K    +KD +A+   E  ++KS NHP +I +  +F+T   +  V  Y +G ELF  L  +    E         ++SAL YLHS  I++RD+K +N+LL ++G +K+ DFG  +E         +  GTP Y++PE++ +  Y    D W  G ++YE+  GR PFY  +   L  +I+   +K+P+ ++++ ++ + GLL KDPKKRL        ++  HPF  S +N +   L    P  KP   S    +Y +KE
Sbjct:  181 TLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFAS-INWTDLVLKKIPPPFKPQVTSDTDTRYFDKE 475          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQW-----PDVLHHPFVESHVNVSPETLTMNSPFTKPLSAS----QYAEKE 918
            +++ +  L+ +G+G+FGKV   R+K T ++ A+K + K    +KD +A+   E  ++KS NHP +I +  +F+T   +  V  Y +G ELF  L  +    E         ++SAL YLHS  I++RD+K +N+LL ++G +K+ DFG  +E         +  GTP Y++PE++ +  Y    D W  G ++YE+  GR PFY  +   L  +I+   +K+P+ ++++ ++ + GLL KDPKKRL        ++  HPF  S +N +   L    P  KP   S    +Y +KE
Sbjct:  181 TLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFAS-INWTDLVLKKIPPPFKPQVTSDTDTRYFDKE 475          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNGV-KLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTN-HSGTSRILAKARQKAQSNKKNIQE 1014
            MD+YH+LE IGEGSFG+VY+GR+K +G++VA+KFIPK G+SEKDL +LKREI+IM+ L HPNI+ +LD+FET +EVV VT+YA+GELFQ+LEDDG+LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL + GV KLCDFGFAR MS+ TLVLTSIKGTPLYMSPEL++EKPYDH+ DLW+LGCILYEL  G PPFYTN+IF+L+ +I++  +KWP  MS+D  SF++GLL K+P+KRL WPD+LHHPFV   V +  +  + N P T P S    A K +Q  EKT   SG  ++L KAR+  +  K N +E
Sbjct:    1 MDQYHILEVIGEGSFGRVYKGRRKFSGQVVALKFIPKVGRSEKDLRSLKREIDIMRGLKHPNIVLLLDSFETEREVVVVTEYAEGELFQILEDDGSLPEKQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSVSTLVLTSIKGTPLYMSPELVEEKPYDHSTDLWSLGCILYELHTGAPPFYTNSIFQLVQLIVRDPVKWPDNMSQDCLSFLKGLLMKEPEKRLSWPDLLHHPFVADGVLMVSDEGSSN-PLTVPPSPDVQALKHQQVAEKTTVRSGEGKLLGKARELREKEKTNRRE 316          

Query:   64 ESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-QWPD----VLHHPF 825
            ++M+ +  L+ +G+G+FGKV   R+K +G+  AMK + K     KD +A+   E  ++K+  HP +  +  +F+T   +  V +Y +G ELF  L  +    E         +VSAL YLHS +I++RD+K +N++L ++G +K+ DFG  +E   D   + +  GTP Y++PE++++  Y    D W LG ++YE+  GR PFY  +  +L  +I+   IK+P+ +S D +S + GLL KDP KRL   PD    ++ H F
Sbjct:  143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSF 404          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDD-GNL-PESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPK---EMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVN--VSPET 858
            MDKY  L+ IGEGSFGK    + +  G    +K I     S K+    ++E+ ++ +++HPNI+Q  ++FE    +  V DY +G +LF+ + +  G+L PE  +      +  AL ++H  +ILHRD+K QNI L+++G V+L DFG AR ++    +  +  GTP Y+SPE+ + KPY++ +D+WALGC+LYE+   +  F   N+  L+  II+G+  +P      S D RS +  L +++P++R     +L  PF+   ++  +SP+ 
Sbjct:    1 MDKYERLKKIGEGSFGKAILVKSRTDGRQYVIKEIGISRMSNKERQESRKEVAVLANMSHPNIVQYKESFEESGCLYIVMDYCEGGDLFKKINNQRGSLFPEEQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYEMCTLKHAFEAGNMKNLVLKIIRGS--YPPVSIHYSPDLRSLLAQLFKRNPRERPSVSTILDKPFLARRIHKFLSPQV 270          

Query:   64 ESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-QWPD----VLHHPFVES 834
            ++M+ +  L+ +G+G+FGKV   R+K +G   AMK + K     KD +A+   E  ++K+  HP +  +  +F+T   +  V +Y +G ELF  L  +    E         +VSAL YLHS +I++RD+K +N++L ++G +K+ DFG  +E   D   + +  GTP Y++PE++++  Y    D W LG ++YE+  GR PFY  +  +L  +I+   IK+P+ +S D +S + GLL KDP KRL   PD    ++ H F  +
Sbjct:  143 KTMNDFDYLKLLGKGTFGKVILVREKASGTYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFTA 407          

Query:   64 ESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-QWPD----VLHHPFVES 834
            ++M+ +  L+ +G+G+FGKV   R+K +G   AMK + K     KD +A+   E  ++K+  HP +  +  +F+T   +  V +Y +G ELF  L  +    E         +VSAL YLHS +I++RD+K +N++L ++G +K+ DFG  +E   D   + +  GTP Y++PE++++  Y    D W LG ++YE+  GR PFY  +  +L  +I+   IK+P+ +S D +S + GLL KDP KRL   PD    ++ H F  +
Sbjct:  143 KTMNDFDYLKLLGKGTFGKVILVREKASGTYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFTA 407          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESD----EHSDPRLLISD-EFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRK--IAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQ-VCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGI------LEGNF----ELTEEDQILWSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYD-CPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDK-----LYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCE----EIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLKKEFLRLLPKER 3951
            M+KYHVL+ IGEGSFG+VY+GR+KH+GE+VA+KFIPK G+SEK+L  LKREI+IM+ L HPNI++MLD+ ET +EVV VT+YA+GELF++LEDDG+ PE +V  I+  LVSAL+YLHSHRILHRDMKPQNILLS++G VKLCDFGFARE+S+DTL++ SIKGTPLYMSPELI E+PYDH +DLWALGCI+YEL VG PPFY ++IF+L++II +  ++WP+ +S +  +F+QGLL KDP  RL WP++L HPF++  V V  E    NSPFT PL+  Q   + +  +     S  SRIL+KARQ+    K   ++P  P         + P P+   +                                   K  PPT  ++RIS DY++          E  + K    +++++  +E+E +SD EW  M + +D    + S P LL+ D  F  +V SR Q C  ++     + A +LRP L+V  N +T  CD  ++     +  +P  ++K++   +   + K+ PW    L DL   +N+Y+     H    P+ +  + +   L F+ +L  + S   + D  L+E  + CL  LC+  +  P      ++  + S++   +D      +I      + +   G++E +    ++  + +      A+ +LC    +  +G   R K  ++ YV+E L S     LFD FV  + +S+ +L  +++LY C  +S  L K++  N   L     +L G+++  D+ S+I        +  +++   Q        + LL+  LL    PS + ++  L   +     P+ +    ++ A +  L D  Q +C   P   G  D +  F+ Q +  +  +S+   + E+    + W RL+  L +      LEG+     E ++ D   W+L+S +GIV FL +++    ++P   +  +    ++++  +  L+  +++  + + C S   + +  I +I+ L  QLLC PF V+  ++   ++L+S  + + V  +   +   L +  AE+ V L+C L +    FL +    V S       L  WL        D+     + C + ++ + L+R       ++  I+ GD ++   L+ LL+ S   + A A +L G L R    +      Q F+  L+  L   D  +R+S+A  +GN+ +H  K      + S   S  FLT LL D   K R +AA+ALGN+G    VL E      +  KV   LL  +C D    ++  S+ ALRSL S  P +++    L   E+
Sbjct:    1 MEKYHVLDLIGEGSFGRVYKGRRKHSGEVVALKFIPKVGRSEKELKGLKREIQIMRDLRHPNIVRMLDSCETEREVVVVTEYAEGELFKILEDDGHFPEELVRDISAQLVSALYYLHSHRILHRDMKPQNILLSKDGTVKLCDFGFARELSLDTLMVRSIKGTPLYMSPELILERPYDHRSDLWALGCIVYELLVGTPPFYAHSIFQLVSIITQQAVRWPRGVSPELTNFLQGLLTKDPAVRLSWPELLRHPFIKDQVVVVEENAN-NSPFTSPLTEEQQQLRNQLCENAGQSSVHSRILSKARQRVAKRK---EKPALPHIKQPENGQQAPAPRISGT-----------------------------------KFSPPTPREHRISEDYDR----------EFSLEKSVRGSIQKVR-LENE-DSDDEWAVMLEATDPSVAQISTPFLLLQDSSFRQRVKSRLQDCCPLV---SLEAASRLRPALRVTCNLLTSGCDPALLSDLCTELQLPQFLLKVINQSLHTDL-KQHPWAVSFLTDLFALLNSYY-----HFKRHPESSSSLQACEGL-FLGVLDFLLSGPQEGDTTLQELGLQCLVSLCESADCSPVPECEKVYNMLQSEHKGLLDK-----IIARSQPPIAKISAGVTEPD----YSAGERLAGFYTEALASLCD---IPPSGEHRRLKENVSLYVSEKLLSDMGC-LFDSFVTSLQHSHCTLSRLKVLYCCCHVSLDLCKRLVSNSCALQCIISLLEGEVSAWDA-SMIHTAGQALFLMSLLVLRLQSLPPQMSRMTLLLLRLLTCDLPSVVVSSTALTCAIQDCGVPIALSQDNLICAIRSALADTPQEICP--PLGSGTFDWVFHFLQQQLNQEEALSLA--VSEEGA--FLWHRLSVLLQVSHQRPRLEGDTPRENECSKPD---WNLLSVRGIVSFLELSLLTSVRDPDRFLSLLAHPDSIAMAAVNRLLTPSFLAHVSEACNSCGWDESDTISEIVILVCQLLCIPFSVETPTEALREILQSLREHQTV-TLLLKTCCHLPQSLAELPVSLVCRLVLMEPDFLAEFSQAVTSSDD----LAIWLGNALHSGQDS-----LTCDLLSVFSHLIRVSSSHLPLLQRIV-GDWEEL--LSWLLQASESGLRAAACTLAGNLARLGETL-----PQSFVKRLLDCLSDRDARVRRSAAFAMGNTAFHGAKGNIYNPWVSTAAS-KFLT-LLRDPQSKTRAHAASALGNLG---SVLGEGGQTSPLMLKVPQLLLQSACTDQEQTVRLASVIALRSL-SETPNVRQHLKSLNAGEK 1215          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESD----EHSDPRLLISD-EFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRK--IAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQ-VCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGI------LEGNF----ELTEEDQILWSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYD-CPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDK-----LYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCE----EIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLKKEFLRLLPKER 3951
            M+KYHVL+ IGEGSFG+VY+GR+KH+GE+VA+KFIPK G+SEK+L  LKREI+IM+ L HPNI++MLD+ ET +EVV VT+YA+GELF++LEDDG+ PE +V  I+  LVSAL+YLHSHRILHRDMKPQNILLS++G VKLCDFGFARE+S+DTL++ SIKGTPLYMSPELI E+PYDH +DLWALGCI+YEL VG PPFY ++IF+L++II +  ++WP+ +S +  +F+QGLL KDP  RL WP++L HPF++  V V  E    NSPFT PL+  Q   + +  +     S  SRIL+KARQ+    K+       P         + P P+   +                                   K  PPT  ++RIS DY++          E  + K    +++++  +E+E +SD EW  M + +D    + S P LL+ D  F  +V SR Q C  ++     + A +LRP L+V  N +T  CD  ++     +  +P  ++K++   +   + K+ PW    L DL   +N+Y+     H    P+ +  + +   L F+ +L  + S   + D  L+E  + CL  LC+  +  P      ++  + S++   +D      +I      + +   G++E +    ++  + +      A+ +LC    +  +G   R K  ++ YV+E L S     LFD FV  + +S+ +L  +++LY C  +S  L K++  N   L     +L G+++  D+ S+I        +  +++   Q        + LL+  LL    PS + ++  L   +     P+ +    ++ A +  L D  Q +C   P   G  D +  F+ Q +  +  +S+   + E+    + W RL+  L +      LEG+     E ++ D   W+L+S +GIV FL +++    ++P   +  +    ++++  +  L+  +++  + + C S   + +  I +I+ L  QLLC PF V+  ++   ++L+S  + + V  +   +   L +  AE+ V L+C L +    FL +    V S       L  WL        D+     + C + ++ + L+R       ++  I+ GD ++   L+ LL+ S   + A A +L G L R    +      Q F+  L+  L   D  +R+S+A  +GN+ +H  K      + S   S  FLT LL D   K R +AA+ALGN+G    VL E      +  KV   LL  +C D    ++  S+ ALRSL S  P +++    L   E+
Sbjct:    1 MEKYHVLDLIGEGSFGRVYKGRRKHSGEVVALKFIPKVGRSEKELKGLKREIQIMRDLRHPNIVRMLDSCETEREVVVVTEYAEGELFKILEDDGHFPEELVRDISAQLVSALYYLHSHRILHRDMKPQNILLSKDGTVKLCDFGFARELSLDTLMVRSIKGTPLYMSPELILERPYDHRSDLWALGCIVYELLVGTPPFYAHSIFQLVSIITQQAVRWPRGVSPELTNFLQGLLTKDPAVRLSWPELLRHPFIKDQVVVVEENAN-NSPFTSPLTEEQQQLRNQLCENAGQSSVHSRILSKARQRVAKRKEK------PVRKQPENGQQAPAPRISGT-----------------------------------KFSPPTPREHRISEDYDR----------EFSLEKSVRGSIQKVR-LENE-DSDDEWAVMLEATDPSVAQISTPFLLLQDSSFRQRVKSRLQDCCPLV---SLEAASRLRPALRVTCNLLTSGCDPALLSDLCTELQLPQFLLKVINQSLHTDL-KQHPWAVSFLTDLFALLNSYY-----HFKRHPESSSSLQACEGL-FLGVLDFLLSGPQEGDTTLQELGLQCLVSLCESADCSPVPECEKVYNMLQSEHKGLLDK-----IIARSQPPIAKISAGVTEPD----YSAGERLAGFYTEALASLCD---IPPSGEHRRLKENVSLYVSEKLLSDMGC-LFDSFVTSLQHSHCTLSRLKVLYCCCHVSLDLCKRLVSNSCALQCIISLLEGEVSAWDA-SMIHTAGQALFLMSLLVLRLQSLPPQMSRMTLLLLRLLTCDLPSVVVSSTALTCAIQDCGVPIALSQDNLICAIRSALADTPQEICP--PLGSGTFDWVFHFLQQQLNQEEALSLA--VSEEGA--FLWHRLSVLLQVSHQRPRLEGDTPRENECSKPD---WNLLSVRGIVSFLELSLLTSVRDPDRFLSLLAHPDSIAMAAVNRLLTPSFLAHVSEACNSCGWDESDTISEIVILVCQLLCIPFSVETPTEALREILQSLREHQTV-TLLLKTCCHLPQSLAELPVSLVCRLVLMEPDFLAEFSQAVTSSDD----LAIWLGNALHSGQDS-----LTCDLLSVFSHLIRVSSSHLPLLQRIV-GDWEEL--LSWLLQASESGLRAAACTLAGNLARLGETL-----PQSFVKRLLDCLSDRDARVRRSAAFAMGNTAFHGAKGNIYNPWVSTAAS-KFLT-LLRDPQSKTRAHAASALGNLG---SVLGEGGQTSPLMLKVPQLLLQSACTDQEQTVRLASVIALRSL-SETPNVRQHLKSLNAGEK 1212          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESD----EHSDPRLLISDE-FIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRK--IAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQ-VCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGI------LEGNF----ELTEEDQILWSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYD-CPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDK-----LYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCE----EIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLKKEFLRLLPKER 3951
            M+KYHVL+ IGEGSFG+VY+GR+KH+GE+VA+KFIPK G+SEK+L  LKREI+IM+ L HPNI++MLD+ ET +EVV VT+YA+GELF++LEDDG+ PE +V  I+  LVSAL+YLHSHRILHRDMKPQNILLS++G VKLCDFGFARE+S+DTL++ SIKGTPLYMSPELI E+PYDH +DLWALGCI+YEL VG PPFY ++IF+L++II +  ++WP+ +S +  +F+QGLL KDP  RL WP++L HPF++  V V  E    NSPFT PL+  Q   + +  +     S  SRIL+KARQ+    K+       P         + P P+   +                                   K  PPT  ++RIS DY++          E  + K    +++++  +E+E +SD EW  M + +D    + S P LL+ D  F  +V SR Q C  ++     + A +LRP       A+ + C+L                                         L  G +    S++  E + P+                L K+ +Q    D+K       CL  LC+  +  P      ++  + S++   +D +     I      + +   G++E +    ++  + +      A+ +LC    +  +G   R K  ++ YV+E L S     LFD FV  + +S+ +L  +++LY C  +S  L K++  N   L     +L G+++  D+ S+I        +  +++   Q        + LL+  LL    PS + ++  L   +     P+ +    ++ A +  L D  Q +C   P   G  D +  F+ Q +  +  +S+   + E+    + W RL+  L +      LEG+     E ++ D   W+L+S +GIV FL +++    ++P   +  +    ++++  +  L+  +++  + + C S   + +  I +I+ L  QLLC PF V+  ++   ++L+S  + + V  +   +   L +  AE+ V L+C L +    FL +    V S       L  WL        D+     + C + ++ + L+R       ++  I+ GD ++   L+ LL+ S   + A A +L G L R    +      Q F+  L+  L   D  +R+S+A  +GN+ +H  K      + S   S  FLT LL D   K R +AA+ALGN+G    VL E      +  KV   LL  +C D    ++  S+ ALRSL S  P +++    L   E+
Sbjct:    1 MEKYHVLDLIGEGSFGRVYKGRRKHSGEVVALKFIPKVGRSEKELKGLKREIQIMRDLRHPNIVRMLDSCETEREVVVVTEYAEGELFKILEDDGHFPEELVRDISAQLVSALYYLHSHRILHRDMKPQNILLSKDGTVKLCDFGFARELSLDTLMVRSIKGTPLYMSPELILERPYDHRSDLWALGCIVYELLVGTPPFYAHSIFQLVSIITQQAVRWPRGVSPELTNFLQGLLTKDPAVRLSWPELLRHPFIKDQVVVVEENAN-NSPFTSPLTEEQQQLRNQLCENAGQSSVHSRILSKARQRVAKRKEK------PVRKQPENGQQAPAPRISGT-----------------------------------KFSPPTPREHRISEDYDR----------EFSLEKSVRGSIQKVR-LENE-DSDDEWAVMLEATDPSVAQISTPFLLLQDSSFRQRVKSRLQDCCPLV---SLEAASRLRP-------ALRVTCNL-----------------------------------------LTSGCDPALLSDLCTELQLPQ---------------FLLKVINQSLHTDLKQ------CLVSLCESADCSPVPECEKVYNMLQSEHKGLLDKI-----IARSQPPIAKISAGVTEPD----YSAGERLAGFYTEALASLCD---IPPSGEHRRLKENVSLYVSEKLLSDMGC-LFDSFVTSLQHSHCTLSRLKVLYCCCHVSLDLCKRLVSNSCALQCIISLLEGEVSAWDA-SMIHTAGQALFLMSLLVLRLQSLPPQMSRMTLLLLRLLTCDLPSVVVSSTALTCAIQDCGVPIALSQDNLICAIRSALADTPQEICP--PLGSGTFDWVFHFLQQQLNQEEALSLA--VSEEGA--FLWHRLSVLLQVSHQRPRLEGDTPRENECSKPD---WNLLSVRGIVSFLELSLLTSVRDPDRFLSLLAHPDSIAMAAVNRLLTPSFLAHVSEACNSCGWDESDTISEIVILVCQLLCIPFSVETPTEALREILQSLREHQTV-TLLLKTCCHLPQSLAELPVSLVCRLVLMEPDFLAEFSQAVTSSDD----LAIWLGNALHSGQDS-----LTCDLLSVFSHLIRVSSSHLPLLQRIV-GDWEEL--LSWLLQASESGLRAAACTLAGNLARLGETL-----PQSFVKRLLDCLSDRDARVRRSAAFAMGNTAFHGAKGNIYNPWVSTAAS-KFLT-LLRDPQSKTRAHAASALGNLG---SVLGEGGQTSPLMLKVPQLLLQSACTDQEQTVRLASVIALRSL-SETPNVRQHLKSLNAGEK 1150          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDEHSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRK--IAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQ-VCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGI------LEGNF----ELTEEDQILWSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYD-CPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDK-----LYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCE----EIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLKKEFLRLLPKER 3951
            M+KYHVL+ IGEGSFG+VY+GR+KH+GE+VA+KFIPK G+SEK+L  LKREI+IM+ L HPNI++MLD+ ET +EVV VT+YA+GELF++LEDDG+ PE +V  I+  LVSAL+YLHSHRILHRDMKPQNILLS++G VKLCDFGFARE+S+DTL++ SIKGTPLYMSPELI E+PYDH +DLWALGCI+YEL VG PPFY ++IF+L++II +  ++WP+ +S +  +F+QGLL KDP  RL WP++L HPF++  V V  E    NSPFT PL+  Q   + +  +     S  SRIL+KARQ+    K+       P         + P P+   +                                   K  PPT  ++RIS DY++          E  + K    +++++  +E+E +SD EW  M     E +DP        + ++++ F     +LL+   D + + R     + + +   C L                                PW    L DL   +N+Y+     H    P+ +  + +   L F+ +L  + S   + D  L+E  + CL  LC+  +  P      ++  + S++   +D +     I      + +   G++E +    ++  + +      A+ +LC    +  +G   R K  ++ YV+E L S     LFD FV  + +S+ +L  +++LY C  +S  L K++  N   L     +L G+++  D+ S+I        +  +++   Q        + LL+  LL    PS + ++  L   +     P+ +    ++ A +  L D  Q +C   P   G  D +  F+ Q +  +  +S+   + E+    + W RL+  L +      LEG+     E ++ D   W+L+S +GIV FL +++    ++P   +  +    ++++  +  L+  +++  + + C S   + +  I +I+ L  QLLC PF V+  ++   ++L+S  + + V  +   +   L +  AE+ V L+C L +    FL +    V S       L  WL        D+     + C + ++ + L+R       ++  I+ GD ++   L+ LL+ S   + A A +L G L R    +      Q F+  L+  L   D  +R+S+A  +GN+ +H  K      + S   S  FLT LL D   K R +AA+ALGN+G    VL E      +  KV   LL  +C D    ++  S+ ALRSL S  P +++    L   E+
Sbjct:    1 MEKYHVLDLIGEGSFGRVYKGRRKHSGEVVALKFIPKVGRSEKELKGLKREIQIMRDLRHPNIVRMLDSCETEREVVVVTEYAEGELFKILEDDGHFPEELVRDISAQLVSALYYLHSHRILHRDMKPQNILLSKDGTVKLCDFGFARELSLDTLMVRSIKGTPLYMSPELILERPYDHRSDLWALGCIVYELLVGTPPFYAHSIFQLVSIITQQAVRWPRGVSPELTNFLQGLLTKDPAVRLSWPELLRHPFIKDQVVVVEENAN-NSPFTSPLTEEQQQLRNQLCENAGQSSVHSRILSKARQRVAKRKEK------PVRKQPENGQQAPAPRISGT-----------------------------------KFSPPTPREHRISEDYDR----------EFSLEKSVRGSIQKVR-LENE-DSDDEWAVML----EATDPS-------VAQISTPF-----LLLQ---DSSFRQR-----VKSRLQDCCPL-------------------------------HPWAVSFLTDLFALLNSYY-----HFKRHPESSSSLQACEGL-FLGVLDFLLSGPQEGDTTLQELGLQCLVSLCESADCSPVPECEKVYNMLQSEHKGLLDKI-----IARSQPPIAKISAGVTEPD----YSAGERLAGFYTEALASLCD---IPPSGEHRRLKENVSLYVSEKLLSDMGC-LFDSFVTSLQHSHCTLSRLKVLYCCCHVSLDLCKRLVSNSCALQCIISLLEGEVSAWDA-SMIHTAGQALFLMSLLVLRLQSLPPQMSRMTLLLLRLLTCDLPSVVVSSTALTCAIQDCGVPIALSQDNLICAIRSALADTPQEICP--PLGSGTFDWVFHFLQQQLNQEEALSLA--VSEEGA--FLWHRLSVLLQVSHQRPRLEGDTPRENECSKPD---WNLLSVRGIVSFLELSLLTSVRDPDRFLSLLAHPDSIAMAAVNRLLTPSFLAHVSEACNSCGWDESDTISEIVILVCQLLCIPFSVETPTEALREILQSLREHQTV-TLLLKTCCHLPQSLAELPVSLVCRLVLMEPDFLAEFSQAVTSSDD----LAIWLGNALHSGQDS-----LTCDLLSVFSHLIRVSSSHLPLLQRIV-GDWEEL--LSWLLQASESGLRAAACTLAGNLARLGETL-----PQSFVKRLLDCLSDRDARVRRSAAFAMGNTAFHGAKGNIYNPWVSTAAS-KFLT-LLRDPQSKTRAHAASALGNLG---SVLGEGGQTSPLMLKVPQLLLQSACTDQEQTVRLASVIALRSL-SETPNVRQHLKSLNAGEK 1156          

Query:  154 IVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKK 1002
            +VA+KFIPK G+SEK+L  LKREI+IM+ L HPNI++MLD+ ET +EVV VT+YA+GELF++LEDDG+ PE +V  I+  LVSAL+YLHSHRILHRDMKPQNILLS++G VKLCDFGFARE+S+DTL++ SIKGTPLYMSPELI E+PYDH +DLWALGCI+YEL VG PPFY ++IF+L++II +  ++WP+ +S +  +F+QGLL KDP  RL WP++L HPF++  V V  E    NSPFT PL+  Q   + +  +     S  SRIL+KARQ+    K+
Sbjct:    2 VVALKFIPKVGRSEKELKGLKREIQIMRDLRHPNIVRMLDSCETEREVVVVTEYAEGELFKILEDDGHFPEELVRDISAQLVSALYYLHSHRILHRDMKPQNILLSKDGTVKLCDFGFARELSLDTLMVRSIKGTPLYMSPELILERPYDHRSDLWALGCIVYELLVGTPPFYAHSIFQLVSIITQQAVRWPRGVSPELTNFLQGLLTKDPAVRLSWPELLRHPFIKDQVVVVEENAN-NSPFTSPLTEEQQQLRNQLCENAGQSSVHSRILSKARQRVAKRKE 284          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNV--SPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAK--------ARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDE-----HSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLD-SKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDG-LLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQIL---------WSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPK-YCQLLRDWLLT-KPAPSSDAQSDCDIKCGVCAILAQLLRFI-PESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQ-MIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSL 3894
            M+KYHVLE IGEGSFG+VY+GRKK++ ++VA+KFIPK G+SEK+L NL+REIEIM+ L HPNI+ MLD+FET KEVV VTDYA+GELFQ+LEDDG LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL++  G+KLCDFGFAR MS +T+VLTSIKGTPLYMSPEL++E+PYDHTADLW++GCILYEL VG PPFYT +IF+L+++I+K  ++WP  +S  F++F+QGLL KDP++RL WPD+LHHPF+   V +   P    + +PFT  L       K+ Q          SRIL +        A+QK   N  +  E       +       P  K+   + +    +                +++ + ++W     P T  +N I+++  +       +     + + S    + ++   +EP+SD EWQ + + S+       S   LL + +F  ++ S+ +   + +L+G  DG   L P+L+++++ ++   D  ++  F  +  +P   + LL    +    ++QPWY  +L DL+  V AYF+     E     ++L ++ + +  F+ LL K+ +Q  D++   R  S++C   LC+ ++     ++   ++++ +     +D LL  L +             +S+  + Q+ +    I     SA+ A+C+      +   A+ ++++++A  L    S +L    +  + +  L L  +++LY C  +S +L   + +    L +   ++ GK+ + D +       +   +  +++   Q      + +G  VA L   S   S + AAA L  QL        ++P E + AA   L    +V    P++ G  DG L+  +  L+    +  +I+ ++   +W   W R +  L + E      E+D +L         W+LISPQG+   L++A+ +FT+E  + +  +    ++ +  ++ L+  +++  +    S  P G   +  ++    +LLCFPF +D+ +D+   +L      ++V  +       L    AE+ +GLL  L++     L Q   TV +  +     L   LL+ +P   SD          + ++L    R + P     +  +L G  + Y PL  LL  S   V  RA  L+G L +HS  +   L+SQ  +  L+          +R+S++  +GN+ Y    L  ++  ++P +T+LL D    +R NAA+ALGN+G     L +E++K +V   LL  +C D    ++E +L ALRSL
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVSLILKDPVRWPSTISSCFKNFLQGLLTKDPRQRLSWPDLLHHPFIAGRVTIITEPAGSDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILRQACKLMAEEAKQKEDQNAGSALEQEDGLCKVTPSTAPVPGLKATPQESSLLAGILAS-------------EMKNNWEDWGAGEAPRTSRENHINLECEQGFPEPRPE----AMGRQS---TDVVDPENEEPDSDDEWQRLLETSEPGPVQLKSPLTLLCNPDFCQRIQSQLRGTGEQILKGVLDGVSHLLPVLRILSSLLSSCNDSVLLYSFCQEAGLPELPLSLLRYSQESSSIQQQPWYGALLRDLVAVVQAYFSCTFNLERSQTGDSLQVFQEAASLFLDLLGKLLAQSDDSEQTFRRDSLMCFAVLCEAVDGNSWAVSKAFYSSLLTTQRAVLDGLLHGLTVPQLPFHTPPGAPQVSQPLREQSEDVPGAIS----SALAAMCTAPVGLPSCWDAKEQVSWHLANQLTED-SSQLRPSLISGLRHHVLCLHLLKVLYACCYISERLCHILGQEPLALESLLMLVQGKVKVADWEE---STEVALYLLSLLVFRLQDLPSGMEKLGSEVATLFTHSHVVSLVNAAACLLGQLGQQGVTFDLQPREWIAAAAHALSAPAEVRLTPPYSCGFYDGLLILLLQLLMQVQGKPGLIRDVVGSEVWTILWHRFSMALRLPE-EVSAQEDDLLLSSPSSLEPDWTLISPQGMAALLSLAMAIFTQESQLCLSHLSQHGSVLMLTLKHLLSPSFLHHL----SQAPQGPEFLPVVVLSVCKLLCFPFALDVDADLLVGVLADLRASEVVVCLLQVCCHHLSLLQAELPIGLLTRLALTDSASLKQFVNTVATSSRAIISFLSVVLLSDQPLMISD----------LLSLLTHTARILSPSHLSFIQELLSGSDESYRPLRSLLGHSENTVRVRAYGLLGHLLQHSMALRGALQSQSGLLNLLLLGLGDKDPAVRRSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDAQDGIRRNAASALGNLGPEG--LGKELLKCQVPQRLLEMACGDPQPTVKEAALIALRSL 1261          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNV--SPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAK--------ARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDE-----HSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLD-SKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQIL---------WSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMN 3219
            M+KYHVLE IGEGSFG+VY+GRKK++ ++VA+KFIPK G+SEK+L NL+REIEIM+ L HPNI+ MLD+FET KEVV VTDYA+GELFQ+LEDDG LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL++  G+KLCDFGFAR MS +T+VLTSIKGTPLYMSPEL++E+PYDHTADLW++GCILYEL VG PPFYT +IF+L+++I+K  ++WP  +S  F++F+QGLL KDP++RL WPD+LHHPF+   V +   P    + +PFT  L       K+ Q          SRIL +        A+QK   N  +  E       +       P  K+   + +    +                +++ + ++W     P T  +N I+++  +       +     + + S    + ++   +EP+SD EWQ + + S+       S   LL + +F  ++ S+ +   + +L+G  DG   L P+L+++++ ++   D  ++  F  +  +P   + LL    +    ++QPWY  +L DL+  V AYF+     E     ++L ++ + +  F+ LL K+ +Q  D++   R  S++C   LC+ ++     ++   ++++ +     +D LL  L +             +S+  + Q+ +    I     SA+ A+C+      +   A+ ++++++A  L    S +L    +  + +  L L  +++LY C  +S +L   + +    L +   ++ GK+ + D +       +   +  +++   Q      + +G  VA L   S   S + AAA L  QL        ++P E + AA   L    +V    P++ G  DGLL  +LQL+    +  +I+ ++   +W   W R +  L + E      E+D +L         W+LISPQG+   L++A+ +FT+E  + +  +    ++ +  ++ L+  +++  +    S  P G   +  ++    +LLCFPF +D+ +D+   +L      ++V  +       L    AE+ +GLL  L++ 
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVSLILKDPVRWPSTISSCFKNFLQGLLTKDPRQRLSWPDLLHHPFIAGRVTIITEPAGSDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILRQACKLMAEEAKQKEDQNAGSALEQEDGLCKVTPSTAPVPGLKATPQESSLLAGILAS-------------EMKNNWEDWGAGEAPRTSRENHINLECEQGFPEPRPE----AMGRQS---TDVVDPENEEPDSDDEWQRLLETSEPGPVQLKSPLTLLCNPDFCQRIQSQLRGTGEQILKGVLDGVSHLLPVLRILSSLLSSCNDSVLLYSFCQEAGLPELPLSLLRYSQESSSIQQQPWYGALLRDLVAVVQAYFSCTFNLERSQTGDSLQVFQEAASLFLDLLGKLLAQSDDSEQTFRRDSLMCFAVLCEAVDGNSWAVSKAFYSSLLTTQRAVLDGLLHGLTVPQLPFHTPPGAPQVSQPLREQSEDVPGAIS----SALAAMCTAPVGLPSCWDAKEQVSWHLANQLTED-SSQLRPSLISGLRHHVLCLHLLKVLYACCYISERLCHILGQEPLALESLLMLVQGKVKVADWEE---STEVALYLLSLLVFRLQDLPSGMEKLGSEVATLFTHSHVVSLVNAAACLLGQLGQQGVTFDLQPREWIAAAAHALSAPAEVRLTPPYSCGFYDGLLILLLQLLM-QGKPGLIRDVVGSEVWTILWHRFSMALRLPE-EVSAQEDDLLLSSPSSLEPDWTLISPQGMAALLSLAMAIFTQESQLCLSHLSQHGSVLMLTLKHLLSPSFLHHL----SQAPQGPEFLPVVVLSVCKLLCFPFALDVDADLLVGVLADLRASEVVVCLLQVCCHHLSLLQAELPIGLLTRLALT 1042          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNV--SPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAK--------ARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDE-----HSDPRLLISDEFIGKVASRF----QYCRDVLLEG--HNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFN 1593
            M+KYHVLE IGEGSFG+VY+GRKK++ ++VA+KFIPK G+SEK+L NL+REIEIM+ L HPNI+ MLD+FET KEVV VTDYA+GELFQ+LEDDG LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL++  G+KLCDFGFAR MS +T+VLTSIKGTPLYMSPEL++E+PYDHTADLW++GCILYEL VG PPFYT +IF+L+++I+K  ++WP  +S  F++F+QGLL KDP++RL WPD+LHHPF+   V +   P    + +PFT  L       K+ Q          SRIL +        A+QK   N  +  E       +       P  K+   + +    +                +++ + ++W     P T  +N I+++  +       +     + + S    + ++   +EP+SD EWQ + + S+       S   LL + +F  ++ S+     + C  VL E    N  AV       ++T   T +  LD +LH      +PF+
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVSLILKDPVRWPSTISSCFKNFLQGLLTKDPRQRLSWPDLLHHPFIAGRVTIITEPAGSDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILRQACKLMAEEAKQKEDQNAGSALEQEDGLCKVTPSTAPVPGLKATPQESSLLAGILAS-------------EMKNNWEDWGAGEAPRTSRENHINLECEQGFPEPRPE----AMGRQS---TDVVDPENEEPDSDDEWQRLLETSEPGPVQLKSPLTLLCNPDFCQRIQSQLRGTGEQCFAVLCEAVDGNSWAVSKAFYSSLLT---TQRAVLDGLLHGLTVPQLPFH 507          

Query: 1807 CDADMKLREQSVL------CLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLD-SKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQL-ITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQIL---------WSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYC-QLLRDWLLT-KPAPSSDAQSDCDIKCGVCAILAQLLRFI-PESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQ-MIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSL 3894
            C+ D   R QS L      C   LC+ ++     ++   ++++ +     +D LL  L +             +S+  + Q+ +    I     SA+ A+C+      +   A+ ++++++A  L    S +L    +  + +  L L  +++LY C  +S +L   + +    L +   ++ GK+ + D +       +   +  +++   Q      + +G  VA L   S   S + AAA L  QL        ++P E + AA   L    +V    P++ G  DGLL  +LQL +    +  +I+ ++   +W   W R +  L + E      E+D +L         W+LISPQG+   L++A+ +FT+E  + +  +    ++ +  ++ L+  +++  +    S  P G   +  ++    +LLCFPF +D+ +D+   +L      ++V  +       L    AE+ +GLL  L++     L Q   TV +  +     L   LL+ +P   SD          + ++L    R + P     +  +L G  + Y PL  LL  S   V  RA  L+G L +HS  +   L+SQ  +  L+          +R+S++  +GN+ Y    L  ++  ++P +T+LL D    +R NAA+ALGN+G     L +E++K +V   LL  +C D    ++E +L ALRSL
Sbjct:  442 CNPDFCQRIQSQLRGTGEQCFAVLCEAVDGNSWAVSKAFYSSLLTTQRAVLDGLLHGLTVPQLPFHTPPGAPQVSQPLREQSEDVPGAIS----SALAAMCTAPVGLPSCWDAKEQVSWHLANQLTED-SSQLRPSLISGLRHHVLCLHLLKVLYACCYISERLCHILGQEPLALESLLMLVQGKVKVADWEE---STEVALYLLSLLVFRLQDLPSGMEKLGSEVATLFTHSHVVSLVNAAACLLGQLGQQGVTFDLQPREWIAAAAHALSAPAEVRLTPPYSCGFYDGLLILLLQLLMQVQGKPGLIRDVVGSEVWTILWHRFSMALRLPE-EVSAQEDDLLLSSPSSLEPDWTLISPQGMAALLSLAMAIFTQESQLCLSHLSQHGSVLMLTLKHLLSPSFLHHL----SQAPQGPEFLPVVVLSVCKLLCFPFALDVDADLLVGVLADLRASEVVVCLLQVCCHHLSLLQAELPIGLLTRLALTDSASLKQFVNTVATSSRAIISFLSVVLLSDQPLMISD----------LLSLLTHTARILSPSHLSFIQELLSGSDESYRPLRSLLGHSENTVRVRAYGLLGHLLQHSMALRGALQSQSGLLNLLLLGLGDKDPAVRRSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDAQDGIRRNAASALGNLGPEG--LGKELLKCQVPQRLLEMACGDPQPTVKEAALIALRSL 1133          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFG 501
            M+KYHVLE IGEGSFG+VY+GRKK++ ++VA+KFIPK G+SEK+L NL+REIEIM+ L HPNI+ MLD+FET KEVV VTDYA+GELFQ+LEDDG LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL++  G+KLCDFG
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFG 145          

Query:   70 MDKYHVLEHIGEGSFGKVYRG-RKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDY-ADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLS---QNGVKLCDFGFAREMSI--DTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKG-TIKWP--KEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLT 864
            +D + + E +G G++  VY+   KK T E+VA+K + K   ++  + NL  EIEI+K + HP+I+Q+ D       +  + ++ A G+L + +     LPE V  +    L SAL +LH   I H D+KPQNILLS   +  +KL DFGFA+ MS   +  VL   +G+PLYM+PE++  + YD   DLW++G ILYE   G+PPF + +  EL   I     I+ P   ++S D R  +Q LL++DP +R+ + D   HP+V+     S E+L 
Sbjct:   11 LDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDNDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVL---RGSPLYMAPEMVCRRQYDARVDLWSVGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPQLSLDCRDLLQRLLERDPARRISFKDFFAHPWVDLEHMPSGESLA 282          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNV--SPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAK--------ARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDE-----HSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLD-SKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDG-LLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQIL---------WSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPK-YCQLLRDWLLT-KPAPSSDAQSDCDIKCGVCAILAQLLRFI-PESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQ-MIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSL 3894
            M+KYHVLE IGEGSFG+VY+GRKK++ ++VA+KFIPK G+SEK+L NL+REIEIM+ L HPNI+ MLD+FET KEVV VTDYA+GELFQ+LEDDG LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL++  G+KLCDFGFAR MS +T+VLTSIKGTPLYMSPEL++E+PYDHTADLW++GCILYEL VG PPFYT +IF+L+++I+K  ++WP  +S  F++F+QGLL KDP++RL WPD+LHHPF+   V +   P    + +PFT  L       K+ Q          SRIL +        A+QK   N  +  E       +       P  K+   + +    +                +++ + ++W     P T  +N I+++  +       +     + + S    + ++   +EP+SD EWQ + + S+       S   LL + +F  ++ S+ +   + +L+G  DG   L P+L+++++ ++   D  ++  F  +  +P   + LL    +    ++QPWY  +L DL+  V AYF+     E     ++L ++ + +  F+ LL K+ +Q  D++   R  S++C   LC+ ++     ++   ++++ +     +D LL  L +             +S+  + Q+ +    I     SA+ A+C+      +   A+ ++++++A  L    S +L    +  + +  L L  +++LY C  +S +L   + +    L +   ++ GK+ + D +       +   +  +++   Q      + +G  VA L   S   S + AAA L  QL        ++P E + AA   L    +V    P++ G  DG L+  +  L+    +  +I+ ++   +W   W R +  L + E      E+D +L         W+LISPQG+   L++A+ +FT+E  + +  +    ++ +  ++ L+  +++  +    S  P G   +  ++    +LLCFPF +D+ +D+   +L      ++V  +       L    AE+ +GLL  L++     L Q   TV +  +     L   LL+ +P   SD          + ++L    R + P     +  +L G  + Y PL  LL  S   V  RA  L+G L +HS  +   L+SQ  +  L+          +R+S++  +GN+ Y    L  ++  ++P +T+LL D    +R NAA+ALGN+G     L +E++K +V   LL  +C D    ++E +L ALRSL
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVSLILKDPVRWPSTISSCFKNFLQGLLTKDPRQRLSWPDLLHHPFIAGRVTIITEPAGSDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILRQACKLMAEEAKQKEDQNAGSALEQEDGLCKVTPSTAPVPGLKATPQESSLLAGILAS-------------EMKNNWEDWGAGEAPRTSRENHINLECEQGFPEPRPE----AMGRQS---TDVVDPENEEPDSDDEWQRLLETSEPGPVQLKSPLTLLCNPDFCQRIQSQLRGTGEQILKGVLDGVSHLLPVLRILSSLLSSCNDSVLLYSFCQEAGLPELPLSLLRYSQESSSIQQQPWYGALLRDLVAVVQAYFSCTFNLERSQTGDSLQVFQEAASLFLDLLGKLLAQSDDSEQTFRRDSLMCFAVLCEAVDGNSWAVSKAFYSSLLTTQRAVLDGLLHGLTVPQLPFHTPPGAPQVSQPLREQSEDVPGAIS----SALAAMCTAPVGLPSCWDAKEQVSWHLANQLTED-SSQLRPSLISGLRHHVLCLHLLKVLYACCYISERLCHILGQEPLALESLLMLVQGKVKVADWEE---STEVALYLLSLLVFRLQDLPSGMEKLGSEVATLFTHSHVVSLVNAAACLLGQLGQQGVTFDLQPREWIAAAAHALSAPAEVRLTPPYSCGFYDGLLILLLQLLMQVQGKPGLIRDVVGSEVWTILWHRFSMALRLPE-EVSAQEDDLLLSSPSSLEPDWTLISPQGMAALLSLAMAIFTQESQLCLSHLSQHGSVLMLTLKHLLSPSFLHHL----SQAPQGPEFLPVVVLSVCKLLCFPFALDVDADLLVGVLADLRASEVVVCLLQVCCHHLSLLQAELPIGLLTRLALTDSASLKQFVNTVATSSRAIISFLSVVLLSDQPLMISD----------LLSLLTHTARILSPSHLSFIQELLSGSDESYRPLRSLLGHSENTVRVRAYGLLGHLLQHSMALRGALQSQSGLLNLLLLGLGDKDPAVRRSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDAQDGIRRNAASALGNLGPEG--LGKELLKCQVPQRLLEMACGDPQPTVKEAALIALRSL 1261          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNV--SPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKA-RQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDE-----HSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLD-SKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQIL-----------WSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPK-YCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQ-MIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSL 3894
            M+KYHVLE IGEGSFG+VY+GR+K++ ++VA+KFIPK G+SEK+L NL+REIEIM+ L HPNI+ MLD+FET KEVV VTDYA+GELFQ+LEDDG LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL++  G+KLCDFGFAR MS +T+VLTSIKGTPLYMSPEL++E+PYDHTADLW++GCILYEL VG PPFY  +IF+L+++I+K  ++WP  +S  F++F+QGLL KDP++RL WPD+L+HPF+  HV +   P    + +PFT  L       K+ Q          SRIL +A ++ A+   +   + TGP  +  ++  K     +   ++   P        +L        +L+ S         P    +NR + D  ++      +    V+ + S T++  +E   +EP+SD EWQ + + ++       +   LL + +F  ++ S+       +L+G  +GA  + P  +V+++ ++   D   +  F  +  +P  ++ LL    +    ++Q WY   L DL+  + AYFA     E     ++L ++ + +  F+ LL K+ +Q  D++  LR  S++C   LC+ ++     I+   ++++ +     +D LL  L +        Q    +S+  + Q+ +    I     SA+ A+C+          A+ ++ +++A  L    S +L    +  + +  L L  +++LY C  +S  L + + +    L + F ++ GK+ + D +       +      +++   Q      + +G  VA L   S   S ++AAA L  QL        ++P E + AA   L    +V    P + G  DGLL  +LQL+T   + S+I+ +    +W   W R +  L + E   E + ++  L           W+LISPQG+   L++A+  FT+EP + +  +    ++ ++ ++ L+  +++  +       P+G+  +  ++    QLLCFPF +D+ +D+   +L    D ++  ++       L     E+ + LL  L++     L+Q   TV + P+     L   LL      SD          + A  A++L   P     +  +L G  + Y PL  LL      V A    L+G L +HS  +   L+SQ  +  L+         ++R S++  +GN+ Y    L  ++  ++P +T+LL D    +R N A+ALGN+G     L EE+++ +V   LL  +C D    ++E +L ALRSL
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS------ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPE----VLGQRS-TDVVDLE--NEEPDSDNEWQHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLSSLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFACTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGNSRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAIS----SALAAICTAPVGLPDCWDAKEQVCWHLANQLTED-SSQLRPSLISGLQHPILCLHLLKVLYSCCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEE---STEVTLYFLSLLVFRLQNLPCGMEKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPE---EASAQEGELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQA----PHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALL------SDQPLLTSDLLSLLAHTARVLS--PSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGPEG--LGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL 1260          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQ-NGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLT--MNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQK-AQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDE-----HSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLD-SKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGI------LEGNFELT-----EEDQILWSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPK-YCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQ-MIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLKKEFLRLLPKERI 3954
            M+KYHVLE IGEGSFG+VY+GR+K++ ++VA+KFIPK G+SEK+L NL+REIEIM+ L HPNI+ MLD+FET KEVV VTDYA+GEL Q+LEDDG LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL++  G+KLCDFGFAR MS +T+VLTSIKGTPLYMSPEL++E+PYDHTADLW++GCILYEL VG PPFY  +IF+L+++I+K  ++WP  +S  F++F+QGLL KDP++RL WPD+L+HPF+  HV +  ET    + +PFT  L       K++Q    +     SRIL +A ++ A+   +   + TGP  +  ++  K     +   ++   P        +L        +L+ S         P    +NR + D  ++      +  E++  + +    + ++  ++EP+SD EWQ + + ++       +   LL + +F  ++ S+       +L+G  +GA  + P  +V+++ ++   D   +  F  +  +P  ++ LL    +    ++Q WY   L DL+  + AYFA     E     ++L ++ + +  F+ LL K+ +Q  D++  LR  +++C   LC+ ++     I+   ++++ +     +D LL+ L +             +S+  + Q+ +    I     SA+ A+C+           + ++ +++A  L    S +L    V  + +  L L  +++LY C  +S +L + + +    L + F ++ GK+ + D +       +      +++   Q      + +G  VA L   S   S ++AAA L  QL        ++P E + AA   L    +V    P + G  DGLL  +LQL+T   + S+I+ +    +W     R +  L +       EG   L+     E D   W+LISPQG+   L++A+  F +EP + +  +    ++ ++ ++ L+  +++  +       P+G+  +  ++    QLLCFPF +D+ +D+   +L    D ++  ++       L     E+ + LL  L++     L+Q   TV + P+     L   LL      SD          + A  A++L   P     +  +L G  + Y  L  LL      V A    L+G L +HS  +   L+SQ  +  L+         ++R S++  +GN+ Y    L  ++  ++P +T+LL D    +R N A+ALGN+G+    L EE+++ +V   LL  +C D    ++E +L ALRSL   +P +++  + L   E++
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELLQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITETAGPDLGTPFTSRLPPELQVLKDKQAHRLSPKGNQSRILTQAYERMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS------ELKSSWAESGTGEAPSAPRENRTTPDCERAFPE---ERPEVLGQRST----DAVDLEDEEPDSDNEWQHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLSSLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFACTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSERTLRRDNLMCFTVLCEAMDGNSRAISKAFYSSLLTTKQVVLDGLLRGLTVPQLPVHTPPGAPQVSQPLREQSEDIPGAIS----SALAAICTAPVGLPDCWDGKEQVCWHLANQLTED-SSQLRPSLVSGLQHPILCLHLLKVLYSCCLVSERLCRLLGQEPLALESLFMLVQGKVKVVDWEE---STEVTLYFLSLLVFRLQNLPCGMEKLGSDVATLFTHSHVASLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLRHRFSMVLRLPKEASAQEGELSLSNPPSPEPD---WTLISPQGMAALLSLAMATFAQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQA----PHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLTQVELPISLLTRLALTDPTSLNQFVNTVAASPRTIISFLSVALL------SDQPLLTSDLLSLLAHTARVLS--PSHLSFIQELLAGSDESYQSLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGLEG--LGEELLQCQVPQRLLEMACGDPQPNVKEAALIALRSL-QQEPGIRQVLVSLGASEKL 1279          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVE 831
            ++ YHV+E +GEGSFG+VY+GR+K+TG+ VAMKFI K GK++KD+ +L++EIEI++ L H NII+MLD+FE  +E   VT++A GELF++LEDD  LPE  V  IA  LV AL YLHS+RI+HRDMKPQNIL+     VKLCDFGFAR MS +T+VL SIKGTPLYM+PEL++E+PYD T DLW+LG ILYEL+VG+PPFYTN+++ L+  I+K  +K+P EMS  F SF++GLL K+P  RL WP +  HPFV+
Sbjct:    3 VEDYHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIMKQGKTDKDIHSLRQEIEILRKLKHENIIEMLDSFENAREFCVVTEFAQGELFEILEDDKCLPEEQVQAIAKQLVKALDYLHSNRIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLYMAPELVKEQPYDRTVDLWSLGVILYELYVGQPPFYTNSVYALIRHIVKDPVKYPDEMSTYFESFLKGLLNKEPHSRLTWPALREHPFVK 257          

Query: 3427 GDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLND-NCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLL 3828
            G+     PL + L    P + A+A S +G + RH+   Y  L     I LLI      D+  +K +   IGN+ YHND LY  ++ SI  L  +L      K + NAA AL N+  +S  LCE+I+    L +LL
Sbjct: 1108 GEASVLQPLKEYLTHVDPNIRAKACSALGNMCRHNGYFYSALAEHQIIGLLIDRCADPDKRTQKFACFAIGNAAYHNDTLYEELRRSITQLANVLTTAEEDKTKANAAGALSNLVRNSNKLCEDIVSKGALQTLL 1242          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQN-GVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPET---LTMNSPFTKP 888
            M++Y V   +G+GSFG VY+  +K   ++VA+K I K G++ K+L NL+RE +I   L HP++I+M+++FE+  ++  VT++A  +L + L  +G + E     + GHLVSAL+YLHS+RILHRD+KPQN+LL +N   KLCDFG AR M++ T VLTSIKGTPLYM+PEL+ E+PYDH AD+W+LGCI YE   G+PPF  ++I  L+ +I    +KWP  ++ + RSF+QGLL+KDP  R+ W  +L HPFVE  + ++ ET       SPFT P
Sbjct:    1 MNRYAVSSLVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATKELKNLRRECDIQARLKHPHVIEMIESFESKTDLFVVTEFALMDLHRYLSYNGAMGEEPARRVTGHLVSALYYLHSNRILHRDLKPQNVLLDKNMHAKLCDFGLARNMTLGTHVLTSIKGTPLYMAPELLAEQPYDHHADMWSLGCIAYESMAGQPPFCASSILHLVKMIKHEDVKWPSTLTSECRSFLQGLLEKDPGLRISWTQLLCHPFVEGRIFIA-ETQAEAAKESPFTNP 276          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNGV-KLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKNIQEPTGPTGDIVNR--------KPK---EPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKID--PPTEVDNRISVDYNKSIQNSHSKNNEIVIN----KDSLTNMEQIEYIEDEPNSDKEWQTMADESDEHSDP----RLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGN-----FELTEEDQIL-------WSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQD-FXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLKKEFLRLLPKERID 3957
            MD YHVLE IGEGSFGKVY+GRKK+  ++VA+KFIPK GK EK+L NL+REI+IM+ L+H NII+MLD+FET KEVV VTDYA+GELFQ+LEDDGNLPE  V +IA  LVSAL+YLHSHRILHRDMKPQNILL + G+ KLCDFGFAR MS +TLVLTSIKGTPLYMSPEL++EKPYDHTADLWALGCILYELF G PPFYTN+IF+L+++IIK  +KWPK M+  F+ F+QGLL K+PK RL WPD+LHHPFV   VNV  E + + SPFT+PL+AS    KE+Q KEK +  GTS+ILAKA++KA   +K       P  +  N         KPK   E E K E             E +     D   V+   S+ +   +I+   PT   +RIS DY K   +   +    V      K+   N+E+++   +E +SD EWQ + D +D+  DP    +LL   +F GK+ +R       +L+G  +GA +LR +L+V+TN +TIKC++ +IL F    +IP  +++L+T+++++   K+QPW QQIL+DL+I +NAYFASEI+  ++  KE +  Y D  L+F+S+ PK+ S   D D++LREQ+VLC  + C+ +E     +AN  FT +S +++  IDALL+       D  + +K+  +++ N      ++D +I   ++ +  + +       G   RRK+A Y+ + L S  + +L D F+    +       ++++Y C Q+S+     IS   + + +   +L GK+ + D +    IE I+H  + I+IQ+Q +P+++S++  + V + L+S   SH AAAALL SQ++     V+++P E+L+A   +  DL Q+C   PF+YGVLDGLL  + +++ + +E  + Q+ ++  IW   W R+AQ L +          ++ EE   +       W+L+SPQG++  L +++ VFTKE    +  +    ++ L  I  L+++ ++  I    S +  G  L  DI+    QL CFPF +DL  D+  ++      + I+  +  +  K+L +   EM +GL+ HL ++ + F+D+   ++K           +L +   PSS     CD    V ++   L+R   ++ ++V S+  G K DY+PL+ +L+     V +RA SL+G L +H    Y +L+ +D  +S LI+ L   D  IRK ++  IGN+ +HN  LY  ++P IP L  LL D   K + NAA+  GNM +HS  LC ++ K KV+  LL+ +CND ++ +Q  ++ +LRSL      LK+E +     E+++
Sbjct:    1 MDNYHVLEIIGEGSFGKVYKGRKKYKAQVVALKFIPKVGKPEKELRNLRREIDIMRGLHHSNIIEMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVKMIACQLVSALYYLHSHRILHRDMKPQNILLGKGGIIKLCDFGFARAMSFNTLVLTSIKGTPLYMSPELVEEKPYDHTADLWALGCILYELFTGTPPFYTNSIFQLVSLIIKDPVKWPKNMTPVFKDFLQGLLTKNPKVRLSWPDLLHHPFVADGVNVREEDVNLPSPFTQPLTASMQIMKEKQAKEKAHPPGTSKILAKAKRKAMEEEKKKGTREIPGAEKYNNNGKEAWGDKPKKSGEGEDKQEQPDTGNGVKAAPTEGERPPS-DAAWVNTGTSKRDEGLEIENLSPTPRTDRISKDYEKEYPSIEIEGRRTVRRSPEKKEKRKNIEKVKLEGEEVDSDDEWQGLIDATDQEGDPEVAMKLLKDQKFHGKLKTRIGNSSGQVLDGMLEGAARLRTVLRVVTNLVTIKCEVALILDFLKALSIPKQVLQLMTEILEKSKVKQQPWCQQILMDLVIALNAYFASEISWCDKLDKEVVQEYYDAMLQFMSVFPKLVSLPADEDLRLREQAVLCGMFTCEVMERNKLHLANQYFTQLSGKHMAAIDALLECT---KPDAQILKKLTELADGNGEAAAERMDTLIQIAVTTLSVMVTLPLTPDEGADGRRKVAHYLGDKLASKGTEQLTDEFLMLSRHPAHCTNVLKVIYACSQVSSVFCSYISNQLNHMDSLMGVLMGKVEVQDMEINSVIEMILHVFSTIVIQLQTLPQVLSESASVFVNIFLESTIASHTAAAALLFSQMIYCGVSVEVQPEEMLQACLSVFTDLQQICVRCPFDYGVLDGLLLLLCEML-AQAEGPVAQMYIDTGIWGTLWHRVAQALQVTNPETDTPIHDIEEEGGPVSGFHSPDWTLVSPQGLMAVLQMSVTVFTKETNQCIPNLAVPDSIILLTIAHLLNKDFLAAIVT--SFDTEGVQLATDIILQVTQLCCFPFAIDLPDDLLTEVQSCLFTVNILPRLLHACNKYLKQAQMEMPLGLIVHLVLSSDDFMDRFIKSLKDLKAL-----SFLSSCIQPSSQEAVICD----VISLCNHLVRSSKDNYQLVKSVFHGTKGDYEPLSAMLRHRSGAVKSRACSLIGNLMKHHGQFYAILKQRDKILSGLIAGLKDEDPHIRKGASYAIGNAAFHNADLYAKLRPVIPVLMDLLRDPVSKTKANAASVFGNMSLHSNTLCSDLKKAKVVARLLDLACNDQHHSVQVSAILSLRSLTRMD-DLKREMVSQKAVEKLN 1314          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNGV-KLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKNIQEP-------TGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMAD--ESDEHSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGI-----------LEGNFELTEE-DQILWSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLS-ETALSLNCIRALIDQTYIQFIYDCPSSEPNGN-VLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVL-ESQDFXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLK 3918
            MD YHVLE IGEGSFGKVY+GRKK++G++VA+KFIPK G+SEK+L NL++EIEIM+ L+H NII+MLD+FET KEVVAVTDYA+GELFQ+LEDDG+LPE  V +IA  LVSALFYLHSHRILHRDMKPQNILL + GV KLCDFGFAR MSI+TLVLTSIKGTPLYMSPEL++EKPYDHTADLWALGCILYELF G+PPFYTN+IF+L+++IIK  +KWPK MS  F+ F+QGLL K+P+ RL WPD+L HPFV   +NVS E L M+SPFTK  +AS    KE+Q KEK N  GTS+IL+KAR+ A    K +++P        G  G+ +    KE     E ++                                  K+  PT   +RIS DY K   +    +   +       N+E ++   +  +SD EWQ + D  ES+E  +  L+ +   + K+ +R Q     +L+G  +GA +LRP+L+V+ N +  K DL+  L F    ++P   ++L+ +++ +    KQPW QQIL+DL+I ++AYFA EI       KE+L+ + D   KF  L+P++  Q  D DM+LR  + +C+  LC  +E   + IA   F+ I+ ++   +DA   ++L  + +    +K+  +++ ++     ++ +++L  +S++ AL         GL A+RKIA+ V E LC        + F++ + +       ++ +Y   Q+S  L   ++ +K  + + F IL G + + D++   T+E  +H+++VI+IQ+Q VP  +     ++V++ L+S   SH AAAALL SQL+  N PV++ P  +L AA  +  DL QVC   PF+YGVLDG+L  + Q+++SD ++ + +L +E  IW+    RLAQ + +           ++     +E+ DQ  W+LISPQG++  L +A  VFTKE +  V  +   ++ L+L     ++    + F+     S P+G  ++++ IL L+ QL CFPF VD++ D+ E++   +    ++  + ++ + FL     EM VGL+  L++  + F+ Q    V              L+  +     +S   + C + +I + L R  PE  +++  I +G + D  PL  L+    P V +R  S++G + +HS+  Y VL + +   S L+  L+  D  +R  S+  +GN+ YH+ +LY  +K S+P+L  LL+D+  K R NAA+ALGN+ +HSP LCEE+ KHK ++S+L  +C+D+ Y +QE +LAAL+S+C+ Q +LK
Sbjct:    1 MDNYHVLELIGEGSFGKVYKGRKKYSGQVVALKFIPKTGRSEKELKNLRKEIEIMRDLHHENIIEMLDSFETEKEVVAVTDYAEGELFQILEDDGSLPEEQVGLIACQLVSALFYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWALGCILYELFTGQPPFYTNSIFQLVSLIIKDPVKWPKNMSPLFKDFLQGLLTKNPQNRLSWPDLLDHPFVAEGINVSEEDLNMDSPFTKSPTASLVFAKEKQAKEKANVPGTSKILSKARKDAAKKGKPVKQPGGWVGGSQGGAGEAMTTADKEKALSQEWNKTEA------------------------------SKMVNPTPRADRISKDYEKEYPSIEVDSRRTLRRSPDRKNIENVKLDGEVVDSDDEWQALEDRTESEEDGNIALMKNKALVNKLKTRLQTSSVQVLDGMLEGAARLRPVLRVLANLVPTKGDLETTLSFIKAVDMPSQQLQLIREVVRKENVLKQPWSQQILVDLVIDIHAYFAIEILETETVKKESLEQFCDNCFKFFDLVPQLLRQNVDDDMRLRHHTFMCVVDLCQTMEVHSK-IAKPFFSGIAEKHTAVVDA---IILCTSAEEEELKKLETVTQGDKAIACQRMGDMVLFAISSLAALTHIPLEVQDGLLAKRKIAYIVGERLCDKKMEPATEEFLRMVRHPQACSMVLKTIYSACQMSPSLCAYLANSKTHMESFFGILQGMVEVEDAELNSTLEMTLHTLSVIVIQLQDVPPDLEKAGDMMVSIFLESTLASHTAAAALLFSQLIYCNLPVEVPPDGMLSAALSVFTDLSQVCVRTPFDYGVLDGILQLLCQMLSSD-QLPMARLYIESGIWNVLIHRLAQMMQVHNPETNMPVHDIDAEIGCSEQTDQTDWTLISPQGLMASLQVAAAVFTKETYQCVPSLAKPDSVLTLT----ILHMYSMPFLRGLQKSNPDGQKMVVETILNLT-QLCCFPFAVDMNEDLLEEIYNCFYSQGLILRLLSACKHFLQPDQMEMPVGLMARLTLGEQAFVLQFADCVVELDA---------LSFVSVCVSPESPLSVICDMVSICSHLARTSPEYVDLLLRIFQGSEGDCAPLASLMCHQSPVVRSRVCSMMGNMMKHSNTFYTVLTQREKLCSSLVRCLEDEDAHVRMCSSYAVGNAGYHSGELYPQLKCSVPYLITLLSDSVAKTRANAASALGNLAMHSPQLCEELSKHKAVHSVLEVACHDSQYTVQESALAALKSMCN-QTELK 1258          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKA--QSNKKNIQEPTGPTGDIVNRKPKEPEPKSETS-QINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNK-----SIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDEHSDP----RLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILE-------GNFELTEEDQIL-----WSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYCQLLRDWLLTKPAPSSDAQ--SDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQD-FXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLKKEFL 3930
            M+ YHVLE IGEGSFGKVY+GRKK++ ++VA+KFIPK GK EK+L NL+REI+IM++L+H NII+MLD+FET KEVV VTDYA+GELFQ+LEDDG+LPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL ++G VKLCDFGFAR MS +TLVLTSIKGTPLYMSPEL++EKPYDHTADLWALGCILYELF G PPFYTN+IF+L+++IIK  +KWPK M+  F+ F+QGLL K+P+ RL WPD+LHHPFV   V+V  E   + SPFT+PLSAS    KE+Q+KEK +  GTS+ILAKAR+KA  +  K + + P+    +  +++   P  K E    I ++        +   + D T   L +  D  ++ I P    D RIS DY K      I+   +        K + ++++ ++   +E +SD EWQ + +++D+  DP    +LL   +F  K+ SR Q     +L+G  +GA +L+ +L+VITN +T+KC+L  I+ F    ++P   + L+ +++D+   K+QPW QQIL+DL+I +NAYFASEI+  ++  K+ +  Y D  ++F+SL+P++  Q  D D++LREQ+VLC  Y C+ +E     +AN  FT ++S+    +D +L   +    D  + +K+  ++E N     ++++ +I   ++ + A+ +           RRKIA Y+ + L    S +L D F   + +       ++++Y C Q+S      IS +   + +   IL GK+ + D +    IET+IH ++ IIIQ+Q +   ++D+ GL++++ L+S   SH AAAALL SQ++     V+++P E+L+A   +  DL Q+C   PF+YGVLDGLL  + +++ + SE  + QL +E  IW   W R+AQ L +          + E+  E+        WSL+SPQG++  L +A+ VFTKE    +  +    ++ L  I  L+ + ++  +Y     + +G  L  D++    QL CFPF VD++ D+ +++ +   + +++  +F +  K+L     E  +GLL  L +  ++F++Q          + Q + D+    P  S+  Q  S   + C V ++   L+R  PE+  +V S+  G K D++PL  LL      V +R  SL+G L +H++  Y  ++ +D     L   L   D  +RK ++  IGN+ +H+ +LY  +KP IP +  LL D   K R NAA+A GN G+HS VL  ++ K KV+  LL+  C +    +Q  ++ ALRSL +    L+KE +
Sbjct:    1 MENYHVLEIIGEGSFGKVYKGRKKYSSQVVALKFIPKVGKPEKELRNLRREIDIMRNLHHENIIEMLDSFETGKEVVVVTDYAEGELFQILEDDGSLPEEQVQQIACQLVSALYYLHSHRILHRDMKPQNILLGKSGIVKLCDFGFARAMSFNTLVLTSIKGTPLYMSPELVEEKPYDHTADLWALGCILYELFTGTPPFYTNSIFQLVSLIIKDPVKWPKNMTPVFKDFLQGLLTKNPRSRLAWPDLLHHPFVAEGVHVREEDTHLQSPFTQPLSASMMILKEKQSKEKAHPPGTSKILAKARKKAMEEEKKSDKEAPSNEEKENSSKEAWGPSKKPEIKLDIKQQQKEVEANQQAGDQWDET--GLSKMTDIREENISPTPRPD-RISKDYEKEYPSIEIEGRRTVRKSPSKEKRNKSHVDNVKLDTEEVDSDDEWQGLIEQTDQEGDPDIALKLLQDVKFQNKLKSRIQTSSAQVLDGMLEGAARLKTVLRVITNLVTLKCELKWIMDFVKALSLPKQPLNLIAEILDKSKVKQQPWCQQILIDLVITLNAYFASEISWNDDIEKDVVKEYYDAMVQFMSLVPQLLFQGMDEDLRLREQAVLCAMYTCEAMERNKLQVANQYFTHLASKQTNTLDCILNCTM---GDPNILKKLTELAEGNGEVATDRMESLIQLAVTTIAAMVNLPLSLDEAADGRRKIALYIGDKLAQKGSEQLADEFFILLRHPAHCSNVLKVVYACCQVSQTFCGYISNSTKHMESLLGILMGKVEIQDMEINAVIETVIHVLSTIIIQLQTMSPALTDSAGLMISIFLESTIASHTAAAALLFSQMIYCGMSVEVQPEEMLQACLAVFTDLQQICVRCPFDYGVLDGLLLLLCEML-AQSEGPVAQLYIETGIWGTLWHRVAQALQVTNPETNAPIHDIEMECEEMPGFHAPDWSLVSPQGLMAVLQLAVTVFTKETNQCIPNLAVPDSIILLTIVHLMHREFLSCMY-----KGDGPQLTVDMILEVTQLFCFPFAVDIAEDILQEVQQCLYETQVLPRIFFACTKYLQLEQIETPMGLLNRLVLGNQMFVEQ----------FAQAVHDFKAV-PFLSNCVQLSSPLSVICDVISMCGHLIRLQPENLTMVKSVFLGMKGDFEPLYLLLSHQSAAVRSRICSLIGNLLKHNNHFYSTIKQKDKIFIALTKCLKDEDPNVRKGASYAIGNAAFHSSELYMKLKPVIPTMMELLRDPMAKTRANAASACGNFGIHSNVLVLDLKKSKVVARLLDLVCREQQQSVQISAILALRSLSNLD-DLRKEMI 1291          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNGV-KLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKN---IQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDD-KIDPPTEVDNRISVDYN-----------KSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEP-----NSDKEWQTMADESDEHSDP----RLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGI-----------LEGNFELTEE--DQILWSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVK--SCPKY-CQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQD-FXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLKKEFLRLLPKERIDXXXXXXXXXXXXXXXXXPIRPSTSTVCRQVSVNNGQKRPLTAGFVKS 4098
            MD YHVLE IGEGSFGKVY GRKK T +IVA+KFIPK GKSEK+L +L+REIEIM+ L+H NII+MLD+FET KEVV VTDYA+GELFQ+LEDDGNLPE  V  IA  LVSALFYLHSHRILHRDMKPQNILL + GV KLCDFGFAR MS +TLVLTSIKGTPLYMSPEL++EKPYDHTADLWALGCI+YELF G PPFYTN+IF+L+N+IIK  +KWPK MS  F+ F+QGLL K+PK RL WP +LHHPFV   + V  E ++++SPFT+PL+AS   +KE+QTKEKT+  G S+ILAKAR+KA  ++K    I       G+     P EP P                             D   SE   DD K   PT   +RIS DY+           ++I+ + +   E         N++Q++   +       +SD EWQ + D +D+  DP     LL   +FI K+ +R++  +  +L+G  +GA +LR LL++ITN +TIKC++  I++F     IP  ++K L D++DRP  K+QPW QQI++D++I +NAYFA EI   ++  K  ++ Y D   +F++L+PK+  Q  D D++LREQ+ LC+ Y+ + +E    DI N  +T+++S+    ++ LL+       D  + +++  + E +  + +++ + +I   +  + A+ +       GL+ +RK+A ++ + L +       + F+  + +       ++I+Y C Q+S  L   IS     + +   IL G++ + D +    IET++H ++ IIIQIQ +P I+S+  G++V   LDS   SH AA ALL SQ+V     V+++P ++L+A   +  D+ ++C   PF+YGVLD  L  +L  + S ++V + QL +E  IW   W R+AQ + +           +EG  ++T +      W+L+SPQG++  L +A+ VFTKE +  +  + +  ++ +  +  L+ + ++Q +  C  +E    V+++ IL ++ QL CFPF VD + ++  ++        I+  +  +S ++L +   E  +GL+  L +   IF++Q    V   +C  + C+ ++        P++     CDI     +I + L+R  P    +V ++ +G K DY+PL  LL  +   V +R  SL+G + +H   +Y VL+ ++   S L+  L   D  +RK ++  +GN+ YHN  LYT +KP+IP L  LL D   K + NAA+A GN+G+HSP LC +I K K++  LL+ +  D +  +Q  SL ALRSLC  Q +LKKE + L    ++  ISS   +           RP T++  R VS  +   RP TA  + S
Sbjct:    1 MDNYHVLEIIGEGSFGKVYSGRKKFTSQIVALKFIPKVGKSEKELRSLRREIEIMRGLHHENIIEMLDSFETAKEVVVVTDYAEGELFQILEDDGNLPEEQVQTIACQLVSALFYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSFNTLVLTSIKGTPLYMSPELVEEKPYDHTADLWALGCIMYELFTGTPPFYTNSIFQLVNMIIKDPVKWPKNMSPVFKDFLQGLLNKNPKLRLSWPQLLHHPFVTHGIKVCQEDISLSSPFTQPLTASMVIKKEQQTKEKTHAPGASKILAKARKKAAEDEKKKKEISARPEAWGNETKSHPPEPMPIHP--------------------------DRPHSEQWADDTKKVEPTPRPDRISKDYHQEYPSIEIEGRRTIKKTPAPGTE----PAGQNNIDQVKLEGEHVEGEEVDSDDEWQGLIDTTDQDGDPDTALGLLDDKQFINKLLTRYKTSKIQVLDGMLEGAARLRSLLRIITNLVTIKCEVGKIVNFTKCMTIPSQLIKTLVDILDRPKVKQQPWCQQIMIDIVIAINAYFAGEIGWSDQLEKPVIEEYVDSMKQFMNLVPKLMFQPVDEDIRLREQTYLCIMYISEVMERDKLDIVNSYYTSLASRNTIALETLLQCT---QSDPLVVKRLSELVEGDMNKANDRFNHMIEMAIGCLTAMVALPMNGDHGLEGKRKVALFLGDKLATEEIADTANNFIILLRHPPNCNNILKIIYACCQVSKNLCLFISNTPQHMESLLGILMGQVEVADMEVNTVIETVLHILSTIIIQIQSLPPIISEAAGMMVTFFLDSTIASHTAAGALLFSQMVYCGVSVEVQPEDMLQACLSVFTDIAEICVRCPFDYGVLD-GLLLLLCELLSQADVPVAQLYIESGIWGTLWHRVAQAIKVSNPDTNLPIHDIEGEGKITIDGFSPPDWNLVSPQGVMAVLQMAVTVFTKETYQCIPNLAAADSVVMLTLVHLLHREFLQVMSKC-LNEDGKEVIVEMILEVT-QLCCFPFAVDTNEELLAEIQHCLYTCNILPRLLFASCEYLNKELLETPIGLIARLVLGNVIFVEQFAQAVHDYNCVSFLCRCIQ--------PTNSLSVICDI----ISICSHLVRTSPAHLPLVMAVFQGQKGDYEPLVTLLTHNSSAVKSRTCSLLGNVMKHDSKMYSVLKQREKVFSSLVKCLQDEDSNVRKGASYAVGNASYHNGDLYTRLKPAIPLLVTLLQDPVSKTKTNAASACGNLGMHSPALCNDIKKLKMIQHLLHVAVTDISPHVQISSLLALRSLC-LQAELKKEMIELNAINKLGNISSGSLS-----------RPGTASSSRPVSAFS---RPGTANSMSS 1322          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKA--QSNKKNIQEPTGPTGDIVNRKPKEPEPKS-ETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDEHSDP----RLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAA-----GLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQIL---------------WSLISPQGIVIFLNIAIHVFTKEPF------VAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVK--SCPKY-CQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDV-LESQDFXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLKKEFLRLLPKERI 3954
            MD YHVLE IGEGSFGKVY+GR+K+TG+IVA+KFIPK GKS+K+L  L+REIEIM+ L+H NII+MLD+F+T KEVV VTDYA+GELFQ+LEDDG+LPE  V IIA  LVSALFYLHSHRILHRDMKPQNILL + G VKLCDFGFAR MS +TLVLTSIKGTPLYMSPEL++EKPYDHTADLWALGCILYELFVG PPFYTN+IF+L+ +IIK  +KWPK MS  F+ F+QGLL K+P+ RL WPD+LHHPFV ++V VS     + SPFT+PLSAS    KE+Q++EK +  GTS+ILA+AR+KA  + +KK           ++   P EP P++ E  Q +                      L   E     K   PT   +RIS DY K   +   +    +  K+   N+E ++   +E +S+ EWQ++ + +D+  +P    R+L     I +   R +     +LEG  +GA +LR +L+VITN +T+KCD+  I+ F +K  +P  I+++L +++     K+QPW QQIL+DL+I +NAYFASEI+  +   K  +D Y     +F+ L+P++ SQ+ DAD++LREQ++LC+ YL + ++          + ++ S+++  +D +L+L      D    + + G+ E  Q     +L++++      + A C  TF+            ++K+A Y+ E L      ++   F+  +         ++++Y C Q S      I E +  L +   +L GK+ + D +    +E +++ +  ++IQ+Q +P  ++    +LV++ LDS   SH AAAALL  Q+V      +++P E+L+A   +  DL +VC   PF +G+LD  L  +L  +   +++ + QL +E  IW   W R+AQ + +   N  L   D  +               W L+SPQG++  L IAI VFTKE +       A +G+L  T + L  ++  +D   I++       +  G  L +D++    QL CFPF VD S D+  ++      ++++  +  +  + L     E  +GL+  + +   IF+ Q  A V+  +C  + C  L +             S   + C V +IL+ L+R  PE   +V  IL+G K D+  L  L+  S   V +R  SL+G L +H   +Y V L+ +  ++ LIS L   D  +RK SA  +GN+ YH+ +LY  +K +IP L +LL+D   K+++NAA+ALGN+G+HS +LC +++K KV+  LL  +C+D    +Q+ +L ALRSLC  Q +L+KE + L   ER+
Sbjct:    1 MDNYHVLEIIGEGSFGKVYKGRRKYTGQIVALKFIPKVGKSDKELRGLRREIEIMRGLHHDNIIEMLDSFDTDKEVVVVTDYAEGELFQILEDDGSLPEEQVQIIATQLVSALFYLHSHRILHRDMKPQNILLGRGGTVKLCDFGFARGMSTNTLVLTSIKGTPLYMSPELVEEKPYDHTADLWALGCILYELFVGTPPFYTNSIFQLVTMIIKDPVKWPKNMSSTFKDFLQGLLSKNPRHRLSWPDLLHHPFVAANVKVSEADSLLESPFTQPLSASMMVLKEKQSREKAHPPGTSKILARARRKAMEEEDKKK----------VLAGLPVEPRPQAWEQDQTDAAIREGKEGE-----------GLNVWETTGISKNMEPTPRLDRISKDYKKEYPSIEVEGRRTLKKKNDQKNIENVKLDGEEVDSEDEWQSLIEATDQDGNPDVALRMLTDPLLIERFRVRLETSSTHVLEGTLEGAARLRSVLRVITNLVTLKCDVSNIIAFTNKVAMPGKILQVLGEILTISSVKEQPWAQQILIDLVITLNAYFASEISWSDNVDKLVIDEYDSAVKQFLELVPELLSQQIDADLRLREQTLLCIIYLSEAMDRSSVSRGEPYYQSLVSEHVPVLDVILQL---SRSDPQTLKNLCGLPEVPQEMALERLEQMV-----GIAAGCLATFVNIPLQGKFATDGKKKVAEYLGEKLTKKEEQEVASGFLLLLHRPADCSTVLKVIYACCQASESFCTYICETETHLESLLALLMGKVEVADMEINTVVEMVLYILCCLVIQVQHLPDRLAGASAMLVSIFLDSTLASHTAAAALLFGQMVACGMSCEVQPDEMLQACLAVFTDLAEVCVRCPFEFGILD-GLLLLLCELLPQTDMPVAQLYIETGIWAAMWHRVAQAMQVTALNCNLPIHDIEVEGQDEKKTWEFIPPGWDLLSPQGLMAALQIAISVFTKETYQCLPNLSAPDGVLMLTLVHLLQVQ-FLDSILIRY-------KQEGKQLQEDLILAVTQLGCFPFAVDASEDLLAEIQHCLYTVELLPRLLGACVRCLNGEALETPIGLVTRMVLGNAIFVHQFAAAVRELNCTGFLCSCLSE------------NSPLSVICDVVSILSHLVRTSPEHLILVMLILQGTKGDFAILTTLMNHSTSVVRSRICSLLGNLMKHDAQLYPVLLQREKILAFLISCLQDEDSNVRKCSAYALGNASYHSAQLYPRLKVAIPALVQLLSDPVSKIKVNAASALGNLGMHSSLLCPDLMKTKVMAHLLETACHDTQPAVQDSALLALRSLCQ-QEELRKELVSLKAAERL 1282          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNGV-KLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKT-NHSGTSRILAKARQKAQSNKKNIQEPT 1020
            M++YHVLE IGEGSFG+VY+GR+K +G++VA+KFIPK G+SEK+L +LKREIEIM+ L HP+I+ +LD+FET +EVV VT+YA+GELFQ+LEDDG LPES V  IA  LVSAL+YLHS+RILHRDMKPQNILL + GV KLCDFGFAR MS+ TLVLTSIKGTPLYMSPEL++EKPYDHT+DLW+LGCILYEL  G PPFYTN+IF L+ +IIK  +KWP+ MSE   SF++GLL KDP+KRL WPD+L HP+V   V V P+  + +SP T   S    A +++Q  EKT   SG  ++L +A+++     +N Q+ T
Sbjct:    1 MEQYHVLEMIGEGSFGRVYKGRRKFSGQVVALKFIPKVGRSEKELRSLKREIEIMRGLKHPHIVLLLDSFETEREVVVVTEYAEGELFQILEDDGCLPESQVRTIACQLVSALYYLHSNRILHRDMKPQNILLGKGGVVKLCDFGFARSMSVSTLVLTSIKGTPLYMSPELVEEKPYDHTSDLWSLGCILYELHTGAPPFYTNSIFHLVQLIIKDPVKWPENMSEGCMSFLKGLLTKDPQKRLAWPDLLKHPYVADGVIVLPDE-SSSSPLTVLPSPDMQALRQQQAAEKTVPRSGEGKLLRRAKEQRDKQHRNRQDST 318          

Query: 2629 PFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQILWSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPN-----GNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNV 3141
            P  +G+ DG+L+   Q + S SE S +   L    W + W ++   L     N   T E       +S  G+ IFL++A+  F+ EP   VE +  E  + L           +    D  S+E       G+     +  +S  LLCFPF ++L  +   ++L SY  L +V  +
Sbjct:  622 PAGWGMSDGVLALTHQFL-SQSESSDLCDFLNSECWGHLWTKVCTMLQ----NTTSTAE------FLSDNGLYIFLSLALFAFSNEPHDCVE-LYFEDGMKL------TRTLSLLLTADSSSTELKRGLLWGSSDTSSLPMMSCHLLCFPFSLELPQEKMTEILHSYQSLNVVTGL 779          

Query:   55 KYPESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLAN-LKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYA-DGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLT 864
            K P S++ + +   +G+G FG VY  R++ T  I+A+K + K    +  + + L+RE+EI   L HPNI+++   F     V  + ++A  GEL+  L+  G   +   +     L  AL Y HS +++HRD+KP+N+LL  NG +K+ DFG++  +   +   +++ GT  Y+ PE+I+ K +D   DLW+LG + YE  VGRPPF T +  E    I +    +P  +SE  R+ I GLL+ +P  RL    VL H +V  H    P + T
Sbjct:  100 KMPWSLENFDIGRALGKGKFGSVYLARERQTKFILALKVLFKKQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDSARVYLILEFAPKGELYGELQRCGMFDDQRSATYIMELADALHYCHSKKVIHRDIKPENLLLGANGELKIADFGWS--VHTPSSRRSTLCGTLDYLPPEMIEGKTHDEKVDLWSLGVLCYEFLVGRPPFETKSHEETYRKISRVEFTYPAHVSEGSRNLINGLLKHNPMHRLPIQGVLTHYWVVEHSTKKPTSFT 370          

Query:   64 ESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-QWPD----VLHHPF 825
            ++M+ +  L+ +G+G+FGKV   R+K +G+  AMK + K     KD +A+   E  ++K+  HP +  +  +F+T   +  V +Y +G ELF  L  +    E         +VSAL YLHS +I++RD+K +N++L ++G +K+ DFG  +E   D   + +  GTP Y++PE++++  Y    D W LG ++YE+  GR PFY  +  +L  +I+   IK+P+ +S D +S + GLL KDP KRL   PD    ++ H F
Sbjct:  143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSF 404          

Query:   55 KYPESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLAN-LKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYA-DGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLT 864
            K P S++ + +   +G+G FG VY  R++ T  I+A+K + K    +  + + L+RE+EI   L HPNI+++   F     V  + ++A  GEL+  L+  G   +   +     L  AL Y HS +++HRD+KP+N+LL  NG +K+ DFG++  +   +   +++ GT  Y+ PE+I+ K +D   DLW+LG + YE  VGRPPF T +  E    I +    +P  +SE  R+ I GLL+ +P  RL    VL H +V  H    P + T
Sbjct:  146 KMPWSLENFDIGRALGKGKFGSVYLARERQTKFILALKVLFKKQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDSARVYLILEFAPKGELYGELQRCGMFDDQRSATYIMELADALHYCHSKKVIHRDIKPENLLLGANGELKIADFGWS--VHTPSSRRSTLCGTLDYLPPEMIEGKTHDEKVDLWSLGVLCYEFLVGRPPFETKSHEETYRKISRVEFTYPAHVSEGSRNLINGLLKHNPMHRLPIQGVLTHYWVVEHSTKKPTSFT 416          

Query:   64 ESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-QWPD----VLHHPF 825
            ++M+ +  L+ +G+G+FGKV   R+K +G+  AMK + K     KD +A+   E  ++K+  HP +  +  +F+T   +  V +Y +G ELF  L  +    E         +VSAL YLHS +I++RD+K +N++L ++G +K+ DFG  +E   D   + +  GTP Y++PE++++  Y    D W LG ++YE+  GR PFY  +  +L  +I+   IK+P+ +S D +S + GLL KDP KRL   PD    ++ H F
Sbjct:  143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSF 404          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTM--NSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDL--ERSEDNWDDKIDPPTEVDNRISVDYNKSI------QNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESD----EHSDPRLLISD-EFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPD-SDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDG----------LLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLG------ILEGNFELTEEDQIL--WSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTY-IQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLL-RFIPESEEIVTSILKGDKDDYDPLNQLLK---DSRPEVLARAISLVGLLTRHSHLVYDVLE--SQDFXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDKL-YTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQ 3906
            M+KYHVLE IGEGSFGKVY+GRK++TG++VA+KFIPK G+S+K+L NL+REI+IM+ L HPNI+QMLD+FET KEVV VTDYA+GELFQ+LEDDGNLPE  V  IA  LVSAL+YLHSHRILHRDMKPQNILL + G VKLCDFGFAR MSI+TLVLTSIKGTPLYMSPEL++EKPYDHTADLW++GCILYELFVG PPFYTN+IF+L+++IIK  +KWPK MS +FR+F+QGLL K+PK RL WP +LHHPFV    ++  + ++    +P T+ LS    A+KE+Q  E    SG S+IL KARQK     KN +E     G+   R+    E K+ +S        K    + +   D   V    +  +D+W  +  PPT   +RI  DY K          + ++ +   +   +  +++ ++   +E +SD EWQ   + +D    + + P  L+SD EF+ ++ +R +     +L+G  +GA +LRP+L VITN +  KCD +++  F     +P + + LL  ++     ++QPW   +LLDL+  + AYFAS+         E+ + +   + +++ +L K+ +Q  D D++L EQ++LCL YLC+ ++     ++   ++++ S       AL+++LL+        QK    S +  V +H +LD++    ++A+ AL +          A+ K+  ++ E L       L +  V  + +   +  A+++LY C Q+S  + K +++   F  +   IL GK+ L   S +   +  +   + V + Q+    + ++  IG   ++ +DS+  +HI A  +L SQ+ +  +  ++    +L ++K  L    ++   +P+ +GV DG             F +  I    E  ++Q   E  +W+  W +LA  L       ++EG+   ++   +   W+LISP G +  LN+A  VF +EP   +  +    ++    +  L+ Q + I        S   G+V++     L+ Q+LCFPF +D+   M   +L +  D +I+  +       L     E+ +GL+  L ++   FL + +  + S  +  + L   L +   P +           V +I + +  R  PE  + +  +  G++     L+Q+L+     R  V A+A  LVG L RHS      L     + +S L + L   +  +R+S++L +GN+ YH   L  +++ P++P +TRLL D  +++R NAAAALGN+G     L E+++  +    L+  +C+D +  ++E +L ALRS+   Q
Sbjct:    1 MEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIKDPVKWPKNMSSEFRNFLQGLLTKEPKLRLSWPALLHHPFVAGKSSIVLDDISAEETNPLTEDLSPELQAQKEKQAAELAPTSGQSKILRKARQKMAEVAKN-KEKDNQCGNAPQRQRGVLEEKA-SSHSALSSKHKSMAKQAVSSADTLAVKQVGDAKKDDWQMENRPPTPKVDRIGADYAKEFPEVEVGSRTLTRQDPSAVPGRANGSIDNVDLDNEEMDSDDEWQHFIEATDPTNLQLTTPMTLLSDAEFLTRIRARLRDSSTQVLDGMLEGASRLRPVLHVITNLLATKCDSELLYTFCCSLELPHHSLMLLEQILASTSVRQQPWCLAVLLDLIALLIAYFASDFNTNPNICSESYERFGKSAEEYIKILQKLMNQSIDTDLRLTEQAMLCLVYLCESMDANSSPVSADFYSSLLSNN----SALIQILLLGTQTQPAVQKKIDKSSAPAV-SHARLDQVSGAFMAAMAALLNFPLKNQPCCVAKTKVVEFIVESLMEPTQHHLIEGLVNDLSHPLKASNALRVLYSCCQMSGSMCKVMADTPKFFISTLHILQGKVPLNRYSQAFELVLHLFTVLLVQLGQVPPELEEMAKYIG---SIFVDSQLITHICATGILISQMTSLGSAAEVNFEVLLNSSKAALTSHIELFIRFPYGFGVCDGLLQLLLQFLCEQLFSVLRILFQGERELVQGFAETEVWNLMWHQLAVGLHLSVCGPVMEGDTPRSDAPGLAPDWTLISPIGTLALLNLAQFVFAQEPQHCIILLSRSNSVVAAVLLKLLTQDFLIHLSSLPILSSLVGSVVL-----LTCQILCFPFAMDVEDAMLTDVLTTLRDTQILTRLMQVCMHQLSEKQLEVPLGLVSRLVLSNAEFLTE-FVRLMSEQETAKYLSRLLASPSCPPATL-------VDVLSIFSHVARRTTPECVDQLLKLFSGNELSTGSLSQMLRVLSHERSTVRAQACGLVGNLLRHSAAPCGSLAVGGSEVLSQLTACLADGEDGVRRSASLALGNAAYHGAGLDASALAPTVPHITRLLQDPLVRIRCNAAAALGNLGAVEG-LREQLVSCRAPQQLVAVACDDVHLSVREAALVALRSMSRSQ 1298          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHR-ILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-----QWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQ 903
            +M+ +  L+ +G+G+FGKV   R+K TG+  AMK + K     KD +A+   E  ++++  HP +  +  +F+T   +  V +Y +G ELF  L  +    E         +VSAL YLH+ + +++RD+K +N++L ++G +K+ DFG  +E   D   + +  GTP Y++PE++++  Y    D W LG ++YE+  GR PFY  +  +L  +I+   I++P+ +S D R+ + GLL+KDPK+RL        +++ H F    +        M  PF KP  AS+
Sbjct:  146 TMNNFDYLKLLGKGTFGKVILVREKATGQYYAMKILKKEVIVAKDEVAHTLTENRVLQTTKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPF-KPQVASE 432          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSII--AGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTI-KWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFV 828
            M++Y ++  IGEGSFGK    + K  G +  +K I     S K+    ++E+ ++ ++ HPNI+   ++FE    +  V DY +G +LF+ +     +  S   I+     L  AL ++H  +ILHRD+K QNI L++ G V+L DFG AR ++  T +  +  GTP Y+SPE+ + KPY+H +D+WALGC+LYE+   R  F   N+  L+  II+G+        S + RS + GLL++DP+ R     +L  P +
Sbjct:    1 MERYTMVSQIGEGSFGKAMLVKSKADGHLYVIKEINISRMSPKERDEARKEVCVLANMRHPNIVSYKESFEERGNLYIVMDYCEGGDLFKRINAQKGVLFSEDQILDWLVQLCLALKHVHDRKILHRDIKSQNIFLTKAGIVQLGDFGIARVLNSTTELARTCIGTPYYLSPEICENKPYNHKSDMWALGCVLYEMCTLRHAFEAGNMKNLVLKIIRGSFPPVSAHYSSELRSTLSGLLRRDPRARPPVAVLLSRPLL 258          

Query:   79 YHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYAD-GELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQN---------GVKLCDFGFA--REMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPK----EMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFV 828
            Y +   +G GSFG VY      TG   A+K + K       +  L+RE+ I+K + H NII + +  ET K V  V +  + GEL  VLE    L E+    +A  L  A+ YLH H I+HRD+K +NIL   +          +++ DFG +  RE +    +L S  GTP+YM+ E+IQ + Y    D+W++G ILY L  G PPF  ++  +L  +IIKG + + +    E+SE  +  ++GLL+ DP  RL   ++LH  +V
Sbjct:    5 YRLGRQLGSGSFGTVYEATHVETGVKWAIKTVNKERAGSSGVRLLEREVVILKRVQHQNIIHLEEVLETHKRVYLVMELCELGELRAVLEQRKRLSEAEARHVAHSLAGAIAYLHKHDIVHRDLKLENILAKSSEPHEGIDHLDIRVTDFGLSAVREGNGAASMLQSPCGTPIYMAAEVIQSQDYSQQCDVWSIGVILYMLLCGEPPFMAHSQEKLFELIIKGELSFTQPAWEEVSESAKELLRGLLKVDPAHRLTASELLHDHWV 270          

Query:   79 YHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKG---GKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL 795
            +  L  +G+GSFGKV   + K  G   A+K + K     K E+     +R + ++K++ HP ++ +  +F++  ++  V DY +G ELF  L+  G+ PES     A  + SA+ YLHS  I++RD+KP+NILL   G + L DFG  +E         +  GTP Y++PE++++ PYD T D W LGC+LYE+  G PPFY+ N+ ++   I+   ++     +    S ++GLL KDP +RL
Sbjct:   92 FDFLTVLGKGSFGKVLLAKHKSDGIFYAVKVMKKSIILQKKEEKHIMAERNV-LVKNVRHPFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILHQPLQLRPCTTNAAISVLEGLLHKDPHQRL 334          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSE-KDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-----QWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQ 903
            S+  + +L  +G GSFG+V+  R +H G   AMK + K      K + +   E  ++  + HP II+M   F+  +++  + DY +G ELF +L      P  V    A  +  AL YLHS  I++RD+KP+NILL +NG +K+ DFGFA+ +   T  L    GTP Y++PE++  KPY+ + D W+ G ++YE+  G  PFY +N  +    I+   +++P   +ED +  +  L+ +D  +RL        DV +HP+ +  V     +  + +P+  P+   Q
Sbjct:   83 SLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLC---GTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQ 366          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSE-KDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-----QWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQ--YAEKERQTKEKTNHS 948
            S+  + +L  +G GSFG+V+  R  H G   A+K + K    + K + +   E  ++  ++HP II+M   F+  ++V  V DY +G ELF +L      P  V    A  +  AL YLHS  I++RD+KP+NILL +NG +K+ DFGFA+ +   T  L    GTP Y++PE++  KPY+ + D W+ G ++YE+  G  PFY +N  +    I+   +K+P     D +  ++ L+ +D  +RL        DV +HP+    +        + +P+  P+   Q   ++ +R  +E+ N+ 
Sbjct:   84 SLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLC---GTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEEFNYG 384          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSE-KDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-----QWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSAS 900
            ++  + ++  +G GSFG+V+  R  H G   A+K + K    + K + +   E  ++K + HP +I+M   F+  + +  V DY +G ELF +L      P  V    A  ++ AL YLH+H I++RD+KP+NILL +NG +K+ DFGFA+E+   T  L    GTP Y++PE+I  KPY+ + D W+LG ++YE+  G  PFY     +    I++G + +P     D    +  L+  D  +R+        D+  HP+    V        + +P+  P+++ 
Sbjct:   66 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLC---GTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSG 348          

Query:   79 YHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIM---KSLNHPNIIQMLDAFETPKEVVAVTDY-ADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPE-LIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKE-MSEDFRSFIQGLLQKDPKKRLQWPD----VLHHPFV 828
            + VL  +G+G+FG+VY+ +KK T  I AMK + K    +K+ +A+   E  I+    S + P I+ +  +F+TP ++  VTDY + GELF  L+ +G   E         LV AL +LH + I++RD+KP+NILL  NG + LCDFG ++    D     +  GT  Y++PE L+ E  Y    D W+LG +++E+  G  PF+  N  ++   I  G +K+P++ +S++ RSF++GLL ++PK RL   D    +  HPF 
Sbjct:  412 FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFF 671          

Query:   91 EHIGEGSFGKVYRGRKKHTGEIVAMKFIPK------GGKSEKDLA---NLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYAD-GELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILL-SQNGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTA-DLWALGCILYELFVGRPPF--YTNNIFELMNIIIKGTIKWPK--EMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNV 846
            E +G GS GKV   + + TG   A+K I K      G  S  D     N++REI IMK L+HPN++ + D +ET   +  + +YA+ GELF +L D G LPE         ++  + Y H+  I+HRD+KP+N+LL S   +K+ DFG A  +  D  +L +  G+P Y +PE++   PY+  A D+W+ G IL+ L  GR PF     N+ +L+  + KG  + P   E+S D +  I  +L  DP++R++  D+L HP ++ +  +
Sbjct:   25 ETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMA-ALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTI 291          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLW 618
            M+ YH+LE IGEGSFGKVY+GR+K+TG  VA+KFIPK G+SEK+L  L+REI+IM+ L H NII++LD+FETP+EV  VT+YA GELFQ+LEDDG LPE  V  IA  LV AL+YLHSHRILHRDMKPQNIL+ ++G VKLCDFGFAR MSI+TLVLTSIKGTPLYMSPEL+QEKPYD+ +DLW
Sbjct:    1 MENYHILELIGEGSFGKVYKGRRKYTGNFVALKFIPKTGRSEKELKCLQREIDIMRGLQHENIIRLLDSFETPQEVCVVTEYAAGELFQILEDDGALPEEQVQRIACQLVKALYYLHSHRILHRDMKPQNILIGKHGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVQEKPYDYNSDLW 184          

Query:   64 ESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLAN-LKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYAD-GELFQVLEDDGN-LPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQN-GVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKNIQEPTGP--TGDIVNRKPKEP 1062
            +S++ + VL+ +G+G F  VYRGR   TG+ VA+K I K       + N +  E+EI   L HP+I+++   FE    V  V + A+ GE  + L   G+ L ES V  I   +V  + YLHSH I+HRD+   NILLS +   K+ DFG A  +S+      ++ GTP Y+SPE+    P+   +D+W++GC+L+ L VG+PPF T  +   +N ++      P  +S + R  I  LL+K+P+ RL    +L HPF+ +         T+N+ ++ P    Q+           + +GT   ++      Q + ++  + +    T DI  R PK P
Sbjct:    8 DSIEDFQVLDLLGKGGFACVYRGRCLATGQEVAIKMIDKKAMRTAGMVNRVCNEVEIHCRLKHPSILELYTYFEDDNYVYLVLELAENGEANRYLRKQGHTLKESEVRRIMLQVVKGVLYLHSHGIIHRDLSLGNILLSSDMDAKIADFGLATRLSLPDEKHYTMCGTPNYISPEIATRDPHGLESDVWSIGCMLFTLLVGKPPFDTEAVRSTLNKVVLAEYDIPNHVSIEARDLISKLLKKNPQDRLTLSGILDHPFITNQ--------TLNTKYSSP--TRQHLNPRAYENSLDSGTGTMATISTGHAPFQQDNRHAVKSSSAERTSDIWPRDPKHP 336          

Query:   61 PESMDKYHVLEHIGEGSFGKVYRGRKKHTG-EIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG---VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFEL-MNIIIKGTIKWP--KEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVE 831
            P  ++ + V E +G+GS+  VY+  KK    ++VA+K I K   S+    NL  EIE++++L H +I+Q+ D       +  + +Y  G +L + +     LPE +       L  AL Y+ S+ + H D+KPQN+LLS      +K+ DFGFA+++  ++   ++I+G+PLYM+PE+I  + YD + DLW++G ILYE   G PPF +    EL   +     IK P    +S D R  +  LLQ+DPK+R+ +     HPF++
Sbjct:   11 PPKINNFVVAEKLGQGSYATVYKAFKKGDNRDVVAIKCIKKKTLSKAATENLLTEIELLRNLEHEHIVQLKDFQWDENHIFLIMEYCGGGDLSRFIHSKRALPERMARKFLRQLACALQYMRSYDVAHMDLKPQNLLLSSRHNPVLKIADFGFAQKLHPNSEA-SNIRGSPLYMAPEMICCQSYDASVDLWSVGVILYETLFGEPPFKSKTFVELEAKLRSSEPIKLPPGPRVSADCRDLLIALLQRDPKQRISFEAFFTHPFID 274          

Query:   79 YHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDY-ADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG----VKLCDFGFAREMSIDTLVLTS-IKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPK----EMSEDFRSFIQGLLQKDPKKRLQWPDVLHHP 822
            Y +LE IGEGSF KV+R  ++ TG   A K +      +K+   +++EI + K L H NI+ +  +    + V  + +Y A G LF  +       E    ++   L++AL YLHS RI+HRD+KP N+LL + G    +KL DFG A+ +  DT V++    G P++++PE + E+P     D+WA G I Y L VG PPF++N+  +L+  I++G    P      +S D R  +  L+  DP+ R+   + L HP
Sbjct:    5 YDMLELIGEGSFAKVFRCIERKTGLEFAAKELRLTDVEDKE--KIEQEIAVWKDLRHENIVSLYSSIREGETVCLIMEYVAGGSLFDEVIQQTYYSEKQARLVTRQLLNALEYLHSRRIVHRDIKPDNLLLKRTGNNVTIKLADFGLAQALPNDTDVISCGASGAPMFLAPETVLEEPIGRAVDIWACGVIFYLLLVGYPPFWSNSDEQLLLSILRGQYTMPSPFWDNVSNDARDLVHKLIVVDPEARISAKEALSHP 260          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSE----KDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYA-DGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEM-SEDFRSFIQGLLQKDPKKRL 795
            ++  + + + +G G+FG+V   R +  GE  A+K +     SE    K + +++ E  I+ S+ HP I+ +L        +  + +YA  GELF  L   G             +VSA+ YLH H I++RD+KP+NILL ++G VKL DFGFA+E+   T  L    GTP Y++PE+IQ K ++   D WALG ++YE+ VG PPF+ +N F +   I+ G ++WPK M +   +  I+ LL  D  +RL
Sbjct:   14 TLQDFELSKTLGTGTFGRVLLARDRRGGEFYALKIM---NISEVIRLKQVEHVQNEKNILMSIEHPFIVNLLWTQHDQTFLYMLLEYACGGELFTYLRTAGRFNNGTGLFFGSEIVSAMDYLHGHSIVYRDLKPENILLDRDGHVKLTDFGFAKEVHDKTWTLC---GTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEKILSGKVEWPKHMDNTSAKDLIKKLLVHDRTRRL 257          

Query:   64 ESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-QWPD----VLHHPFVES 834
            ++M+ +  L+ +G+G+FGKV   R+K +G   AMK + K     KD +A+   E  ++K+  HP +  +  +F+T   +  V +Y +G ELF  L  +    E         +VSAL YLHS +I++RD+K +N++L ++G +K+ DFG  +E   DT  + +  GTP Y++PE++++  Y    D W LG + YE+  GR PFY  +  +L  +I+   IK+P+ +S D +S + GLL KDP KRL   PD    ++ H F  +
Sbjct:  143 KTMNDFDYLKLLGKGTFGKVILVREKASGTYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDTATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVTYEMMCGRLPFYNQDHEKLFELILMEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFST 407          

Query:   64 ESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-QWPD----VLHHPF 825
            ++M  +  L+ +G+G+FGKV   R+K +G+  AMK + K     KD +A+   E  ++K+  HP +  +  +F+T   +  V +Y +G ELF  L  +    E         +VSAL YLHS +I++RD+K +N++L ++G +K+ DFG  +E   D   + +  GTP Y++PE++++  Y    D W LG + YE+  GR PFY  +  +L  +I+   IK+P+ +S D +S + GLL KDP KRL   PD    ++ H F
Sbjct:  101 KTMSDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALNYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVTYEMMCGRLPFYNQDHEKLFELILMEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSF 362          

Query:   64 ESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-QWPD----VLHHPF 825
            ++M  +  L+ +G+G+FGKV   R+K +G+  AMK + K     KD +A+   E  ++K+  HP +  +  +F+T   +  V +Y +G ELF  L  +    E         +VSAL YLHS +I++RD+K +N++L ++G +K+ DFG  +E   D   + +  GTP Y++PE++++  Y    D W LG + YE+  GR PFY  +  +L  +I+   IK+P+ +S D +S + GLL KDP KRL   PD    ++ H F
Sbjct:  140 KTMSDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALNYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVTYEMMCGRLPFYNQDHEKLFELILMEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSF 401          

Query:   64 ESMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-QWPD----VLHHPF 825
            ++M  +  L+ +G+G+FGKV   R+K +G+  AMK + K     KD +A+   E  ++K+  HP +  +  +F+T   +  V +Y +G ELF  L  +    E         +VSAL YLHS +I++RD+K +N++L ++G +K+ DFG  +E   D   + +  GTP Y++PE++++  Y    D W LG + YE+  GR PFY  +  +L  +I+   IK+P+ +S D +S + GLL KDP KRL   PD    ++ H F
Sbjct:  143 KTMSDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALNYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVTYEMMCGRLPFYNQDHEKLFELILMEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSF 404          

Query:   67 SMDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKD-LANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADG-ELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRL-QWPD----VLHHPFVES 834
            +M  +  L+ +G+G+FGKV   ++K TG   AMK + K     KD +A+   E  ++++  HP +  +  AF+T   +  V +YA+G ELF  L  D    E         +VSAL YLHS  +++RD+K +N++L ++G +K+ DFG  +E   D   + +  GTP Y++PE++++  Y    D W LG ++YE+  GR PFY  +   L  +I+   I++PK ++ + ++ + GLL+KDPK+RL   PD    V+ H F  S
Sbjct:  149 TMSDFDYLKLLGKGTFGKVILVKEKATGMYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTTLKYAFQTHDRLCFVMEYANGGELFFHLSRDRVFTEDRARFYGAEIVSALEYLHSRDVVYRDLKLENLMLDKDGHIKITDFGLCKEGVTDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPKNLAPEAKALLAGLLKKDPKQRLGGGPDDAKEVMTHKFFIS 412          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINXXXXXXXXXXXXXXXXDNTLVDLERSEDNWDDKIDPPTEVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEQIEYIEDEPNSDKEWQTMADESDEHSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLTDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLXXXXXXXXXXXXXXXXXXXXXXXXSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEXXXXXXXXXXXXXQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQILWSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNEKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFXXXXXXXXXXXXQMIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLKKEFLRLLPKERIDXXXXXXXXXXXXXXXXXPIRPSTSTVCRQVSVNNGQKRPLTAGFVKSRIYNQMSTEKSIQSKTIDNHKLNSIMGHLMYLSDILSVSD 4218
            MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINKKPLLKVPEPKLLQKPDNTLVDL+R             +VDNRISVDYNKSIQNSHSKNNEIVINKDSLTNME IEYIEDEPNSDKEWQTMADESDEHSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLL DLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLITIETIIHSITVIIIQIQQVPKIVSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEILKAAKILLIDLDQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQILWSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMN+KLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFISLLISNLDSSDQMIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLK+EFLRLLPKERIDKISSKISTASQSSGSKIPIRPSTSTVCRQVSVNNGQKRPLTAGFVKSRIYNQMST+KSIQSKTIDNHKLNSIMGHLMYLSDILSVSD
Sbjct:    1 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNGVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVESHVNVSPETLTMNSPFTKPLSASQYAEKERQTKEKTNHSGTSRILAKARQKAQSNKKNIQEPTGPTGDIVNRKPKEPEPKSETSQINKKPLLKVPEPKLLQKPDNTLVDLDR-------------KVDNRISVDYNKSIQNSHSKNNEIVINKDSLTNMEHIEYIEDEPNSDKEWQTMADESDEHSDPRLLISDEFIGKVASRFQYCRDVLLEGHNDGAVKLRPLLKVITNAITIKCDLDIILHFYDKTNIPFNIMKLLIDLIDRPVAKKQPWYQQILLDLLIGVNAYFASEIAHENEAPKEALDMYSDISLKFVSLLPKIFSQKCDADMKLREQSVLCLKYLCDRLETRPEDIANMIFTTISSQYIQCIDALLKLLLIWNDDTFLNQKIRGMSESNQVQTHNKLDEIILHTLSAVHALCSTTFLEAAGLKARRKIAFYVAEYLCSSFSVKLFDLFVQFIGYSNLSLGAIQILYVCLQLSTKLSKKISENKDFLHTCFQILHGKITLPDSDSLITIETIIHSITVIIIQIQQVPKIVSDNIGLLVALLLDSKFPSHIAAAALLCSQLVTYNTPVQIEPHEILKAAKILLIDLDQVCTMYPFNYGVLDGLLSFVLQLITSDSEVSIIQLILEKSIWDYFWQRLAQTLGILEGNFELTEEDQILWSLISPQGIVIFLNIAIHVFTKEPFVAVEGMLSETALSLNCIRALIDQTYIQFIYDCPSSEPNGNVLIQDILTLSIQLLCFPFVVDLSSDMNDKLLESYSDLKIVYNVFASSEKFLVRGHAEMVVGLLCHLSMNGEIFLDQIYATVKSCPKYCQLLRDWLLTKPAPSSDAQSDCDIKCGVCAILAQLLRFIPESEEIVTSILKGDKDDYDPLNQLLKDSRPEVLARAISLVGLLTRHSHLVYDVLESQDFISLLISNLDSSDQMIRKSSALVIGNSLYHNDKLYTSIKPSIPFLTRLLNDNCLKVRINAAAALGNMGVHSPVLCEEIIKHKVLNSLLNQSCNDANYEIQEVSLAALRSLCSFQPQLKEEFLRLLPKERIDKISSKISTASQSSGSKIPIRPSTSTVCRQVSVNNGQKRPLTAGFVKSRIYNQMSTDKSIQSKTIDNHKLNSIMGHLMYLSDILSVSD 1370          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAF--ETPKEVVAVTDYADGELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQNG-VKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDHTADLWALGCILYELFVGRPPFYTNNIFELMNIII---KGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVE 831
            ++KY + E +G+G+ G VY    K TG+ +A+K +    + +KDL  +  EI +M++  HPNI+  LD+F  +  KE+  V +Y DG     +  +  + E+ ++ +    + AL +LHS  ++HRD+K  NILL  +G VKL DFGF  ++S D    T++ GTP +M+PE++ +K Y    D+W+LG +  E+  G PP+   N  + + +I    K  +K  + MS +F+ F+   L+ D +KR    D+L+HPF++
Sbjct:  357 LEKYVLDEKVGQGASGVVYSSTNKSTGKPLAIKQMTLASQPKKDL--IVNEILVMRAHRHPNIVNYLDSFLVDDNKELWVVMEYLDGGSLTDVVTEAFMQENQIATVCRETLQALEFLHSKHVIHRDIKSDNILLGLDGQVKLTDFGFCAQLSNDLTKRTTMVGTPYWMAPEVVTKKQYGPKVDVWSLGIMALEMLDGEPPYLNENPIKALYLIATNGKPDVKEAQNMSTEFKDFLDCCLEVDVEKRWSASDLLNHPFIQ 614          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYAD-GELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQN-GVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDH-TADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVES 834
            + KY +++ IG+G+F KV   +   TG+ VA+K I K   +   L  L RE+ IMK+++HPNI+++ +  E+ + V  V +YA  GE+F  L  +G + E    +    +VSA+ Y H  +I+HRD+K +N+LLS +  +K+ DFGFA    +    L +  G+P Y +PEL Q + Y+    D+W+LG ILY L  G  PF  +N+ EL   +++G  + P  M+ D  + ++ +L  +P KR    DV+   ++ +
Sbjct:   18 IGKYKLIKTIGKGNFAKVKLAQHVTTGKKVAVKVIDKTALNNSSLQKLFREVRIMKTIDHPNIVKLFEVIESERHVYLVMEYASRGEVFDYLVQNGRMKEKDARLRFREIVSAIQYCHHKQIVHRDLKAENLLLSNDLQIKIADFGFANNFDVKKQ-LDTFCGSPPYAAPELFQGRKYEGPEVDVWSLGVILYTLVSGSLPFDGHNMRELRERVLRGKYRIPFYMTTDCETLLKKMLIVNPMKRFTLLDVMKDKWINT 274          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYAD-GELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQN-GVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDH-TADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVES 834
            + KY +++ IG+G+F KV   +   TG+ VA+K I K   +   L  L RE+ IMK+++HPNI+++ +  E+ + V  V +YA  GE+F  L  +G + E    +    +VSA+ Y H  +I+HRD+K +N+LLS +  +K+ DFGFA    +    L +  G+P Y +PEL Q + Y+    D+W+LG ILY L  G  PF  +N+ EL   +++G  + P  M+ D  + ++ +L  +P KR    DV+   ++ +
Sbjct:   30 IGKYKLIKTIGKGNFAKVKLAQHVTTGKKVAVKVIDKTALNNSSLQKLFREVRIMKTIDHPNIVKLFEVIESERHVYLVMEYASRGEVFDYLVQNGRMKEKDARLRFREIVSAIQYCHHKQIVHRDLKAENLLLSNDLQIKIADFGFANNFDVKKQ-LDTFCGSPPYAAPELFQGRKYEGPEVDVWSLGVILYTLVSGSLPFDGHNMRELRERVLRGKYRIPFYMTTDCETLLKKMLIVNPMKRFTLLDVMKDKWINT 286          

Query:   70 MDKYHVLEHIGEGSFGKVYRGRKKHTGEIVAMKFIPKGGKSEKDLANLKREIEIMKSLNHPNIIQMLDAFETPKEVVAVTDYAD-GELFQVLEDDGNLPESVVSIIAGHLVSALFYLHSHRILHRDMKPQNILLSQN-GVKLCDFGFAREMSIDTLVLTSIKGTPLYMSPELIQEKPYDH-TADLWALGCILYELFVGRPPFYTNNIFELMNIIIKGTIKWPKEMSEDFRSFIQGLLQKDPKKRLQWPDVLHHPFVES 834
            + KY +++ IG+G+F KV   +   TG+ VA+K I K   +   L  L RE+ IMK+++HPNI+++ +  E+ + V  V +YA  GE+F  L  +G + E    +    +VSA+ Y H  +I+HRD+K +N+LLS +  +K+ DFGFA    +    L +  G+P Y +PEL Q + Y+    D+W+LG ILY L  G  PF  +N+ EL   +++G  + P  M+ D  + ++ +L  +P KR    DV+   ++ +
Sbjct:   30 IGKYKLIKTIGKGNFAKVKLAQHVTTGKKVAVKVIDKTALNNSSLQKLFREVRIMKTIDHPNIVKLFEVIESERHVYLVMEYASRGEVFDYLVQNGRMKEKDARLRFREIVSAIQYCHHKQIVHRDLKAENLLLSNDLQIKIADFGFANNFDVKKQ-LDTFCGSPPYAAPELFQGRKYEGPEVDVWSLGVILYTLVSGSLPFDGHNMRELRERVLRGKYRIPFYMTTDCETLLKKMLIVNPMKRFTLLDVMKDKWINT 286