Tyrosine-protein kinase

Query:   94 SRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFE--ISGGNRGKEKCTLLLNFLKFVEKVQDED-----------LDNKKNVFQIAYVEDI-----LSTNRNILYIVANSAAERDDWI----NLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKP-NSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSK---DPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSP-PMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQ 2205
            S   KRSQ+K   S   +K + F+LT   L Y+E     G RG +K ++ +  +  VE V  E             +    + QI+ +E       +  +   LY+ + +   R  WI    N+IRY +       + +YHP  W   G+Y CC   ++ +MGCQ              N NG+                        G++H    +  P          PT     +             V+ S+              K V+A+++Y P+  N L L+KG+ YF+++ SN  WW  +   G  GY+P+NY+ +  +S+  ++WY K +TR QAE +L +E +EG F+VRDS SK   YT+SV +K   DP+      + HY              P   YYL+EKH F TI ++I+YH+HNS GL+ RL+ P   ++  +P TAG+G   +E+DP +L      +G GQFGVVK G++R +  VA+K + EG+M+ED+FI+EAK M  L+H  LVQL+GV  K+RPI IITEYM +G L ++LR     +  +   L ++C  V + M YLE + F+HRDLAARNCLV         VKV+DFG++R++LD+ Y  S G+KFPVRW+PPEV   S ++ K+D+W+FGVLMWE+++   + PY    NS+  ++I  G RL +P +  +++Y +M  CW     +RP F+ +   I D +D+
Sbjct:    8 SIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNS-----DLVQKYHPCFWID-GQYLCCSQTAKNAMGCQILE-----------NRNGSLKP---------------------GSSHRKTKKPLP----------PTPEEDQILKKPLPPEPAAAPVSTSEL-------------KKVVALYDYMPMNANDLQLRKGDEYFILEESNLPWWRARDKNGQEGYIPSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGDPQGV----IRHY---------VVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGSWEIDPKDLTFLKE-LGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG----VVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYS-LGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDE 657          

Query:   94 SRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFE--ISGGNRGKEKCTLLLNFLKFVEKVQDED-----------LDNKKNVFQIAYVEDI-----LSTNRNILYIVANSAAERDDWI----NLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKP-NSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSK---DPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSP-PMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQN 2208
            S   KRSQ+K   S   +K + F+LT   L Y+E     G RG +K ++ +  +  VE V  E             +    + QI+ +E       +  +   LY+ + +   R  WI    N+IRY +       + +YHP  W   G+Y CC   ++ +MGCQ              N NG+                        G++H    +  P          PT     +             V+ S+              K V+A+++Y P+  N L L+KG+ YF+++ SN  WW  +   G  GY+P+NY+ +  +S+  ++WY K +TR QAE +L +E +EG F+VRDS SK   YT+SV +K   DP+      + HY              P   YYL+EKH F TI ++I+YH+HNS GL+ RL+ P   ++  +P TAG+G   +E+DP +L      +G GQFGVVK G++R +  VA+K + EG+M+ED+FI+EAK M  L+H  LVQL+GV  K+RPI IITEYM +G L ++LR     +  +   L ++C  V + M YLE + F+HRDLAARNCLV         VKV+DFG++R++LD+ Y  S G+KFPVRW+PPEV   S ++ K+D+W+FGVLMWE+++   + PY    NS+  ++I  G RL +P +  +++Y +M  CW     +RP F+ +   I D +D+ 
Sbjct:   42 SIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNS-----DLVQKYHPCFWID-GQYLCCSQTAKNAMGCQILE-----------NRNGSLKP---------------------GSSHRKTKKPLP----------PTPEEDQILKKPLPPEPAAAPVSTSEL-------------KKVVALYDYMPMNANDLQLRKGDEYFILEESNLPWWRARDKNGQEGYIPSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGDPQGV----IRHY---------VVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGSWEIDPKDLTFLKE-LGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG----VVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYS-LGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 692          

Query:  826 ENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSP-PMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCE 2214
            +NS++ V+A++++     + L L++G+ Y +++ ++  WW  +   G+ GY+P+NY+   K N+L  ++WY +++ R +AE +L  E++EG F+VRDS S+   YT+S+ +K     G     HYH            +P   YYL+EKHAF +I ++I YHKHN+ GLV RLR P  ++   +P TAG   +++E++P+EL      +G G FGVV+ G++R +  VA+K + EGAM E+DFI+EAK M  L HP LVQL+GV  +++PI I+TE+M+ G L +FLR R   +F+R V+L+ +C  V +GM YLE  +F+HRDLAARNCLV         VKV+DFGMAR++LD+ Y  S+G KFPV+W PPEVF  S ++ K+DVWSFGVLMWEVFT     P+    N +V   +  G RL +P +  + +Y +ML CWQ  P+ RP+FE + + I + ++  CE
Sbjct:  178 DNSEEIVVAMYDFQAAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNYVTGKKSNNLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDS-SQPGLYTVSLYTKFG-GEGSSGFRHYHIKETTT------SPK-KYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELTF-MRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQG-HFSRDVLLS-MCQDVCEGMEYLERNSFIHRDLAARNCLVSEAG----VVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFT-EGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVE--CE 626          

Query:  100 MCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDED-LDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQ----------EASPPGPVDRR 555
            + KRSQ+K   S   YK + FVLT + L Y+E     +   K  + ++ +K VE V+++D +   +N +    V D      N LYI A S   RD W+  ++   K+     + +YHP  W   G Y CC    + + GC+          +A PP P  ++
Sbjct:   11 LIKRSQQKKKTSPLNYKERLFVLTKSMLTYYE-GRAEKKYRKGFIDVSKIKCVEIVKNDDGVIPCQNKYPFQVVHDA-----NTLYIFAPSPQSRDLWVKKLKEEIKNN-NNIMIKYHPKFWTD-GSYQCCRQTEKLAPGCEKYNLFESSIRKALPPAPETKK 165          

Query:  784 NVSQKPAAINIEGD-----ENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPP-MRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEF-RRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGD 2193
            N S+KP     E +     E  +  VIA+++Y      +L L++ E Y ++DSS   WW V+   G  GYVP++Y+    PN+L T++WY K ++R +AE +LL+  +EG F+VRDS +   TYT+SV +K   +     + HYH      +      P   YY++EK+ F +I  +I+YH+HN GGLV RLR P      ++PVTAG+   ++ +DP+EL      IG GQFG+V  G +  +  VA+K + EGAM+E+DFI+EA+ M  L+HP LVQL+GV +++ PI ++ E+M+HG L D+LR +   +      L  +C  V +GMAYLE    +HRDLAARNCLV      +  +KV+DFGM RF+LD+ Y  S GTKFPV+WA PEVF  S Y+ K+DVWSFGVLMWEVF+   + PY  ++NS+V + I  G RL KP +    +Y +M  CW+  P+ RPAF  + +++ +
Sbjct:  151 NASKKPLPPTPEDNRRPLWEPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTA-GTYTVSVFTKAVVSENNPCIKHYH------IKETNDNPK-RYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPVTAGLRYGKWVIDPSELTF-VQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAE--TLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVG----ENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFS-EGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAE 614          

Query:   97 RMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLD---NKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEAS----------PPGPVDRR 555
            ++ K+SQ+K   S   +K++ FVLT   L YFE   G +   K ++ L+ +K VE V+  D+    + K  FQ+ +       +  +LY+ A     R  W+  ++   ++   + +P+YHP  W   G++ CC  + + + GC +            PP P D R
Sbjct:   10 QLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRIKCVEIVKS-DISIPCHYKYPFQVVH-------DNYLLYVFAPDRESRQRWVLALKEETRNN-NSLVPKYHPNFWMD-GKWRCCSQLEKLATGCAQYDPTKNASKKPLPPTPEDNR 165          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSP-PMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGD 2193
            V A++++ P     L L++ E Y +++  N  WW  +   G+ G +P+NY+  +K  +L  ++WY++++TR QAE +L +E++EG F+VRDS     +YT+SV        G  +       H ++   D G     +Y++E+HAFQ+I ++I YH+HN+ GL+ RLR P  +     P TAG   +++E+DP+EL      IG GQFGVV  GE+R  + VA+K + EG+M+E+DFI+EAK M  L+H  LVQL+GV ++++P+ I+TE+M++G L ++LR        R  +L  +C  + +GM YLE   ++HRDLAARNCLV +    +  VK++DFGM R++LD+ Y  S G KFP++W+PPEVF  + Y+ K+DVWSFGVLMWEVFT   + P+  K+N QV + I  G RL +P + P  +Y +M  CW   P+ RP F  + + + +
Sbjct:   87 VKALYDFLPREPCNLALRRAEEYLILEKYNPHWWKARDRLGNEGLIPSNYVTENKITNLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRDS-RHLGSYTISVF------MGARRSTEAAIKHYQIKKNDSG----QWYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELAF-IKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKL--RKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSS----TCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFT-EGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTE 522          

Query:  637 LGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQ---------PINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVK-SAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEE-NREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLL-DNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLD 2202
            +GS +G       E+PP   TS   +  T     L          PI AS      + N        NI    N     +A+  Y+   ++ L  +K +   +++ +   WW+ +  A G  GY+P+NY+ +  S+ +  WY+  + R  AE  LL   N  G FLVRDS S+++  +LSV   D        V HY    ++     GG     Y+++ +  F T+ D+I +++  + GL   L +P  +      T     D++E+D   ++L    IG GQFG V +G +   +PVAVK++  G  +  DF+ EA+ M+ L HP L+ L+ V  +  PI+I+TE M+  +L  FL+ R      +   L +I AQVA GMAYLE  NF+HRDLAARN L+      S+ VK+ADFG+AR L+ +N YE   G +FP++W  PE    + +T K+DVWSFG+L+ E+ T     PY G  N++V Q +  G R+  P  CP  LY +M +CW+ DP KRP FE +  K+ D  +
Sbjct:    1 MGSCIGK------EDPPPGATSPVHTSSTLGRESLPSHPRIPSIGPIAASSSGNTIDKNQ-------NISQSAN----FVALFQYDARTDDDLSFKKDDILEILNDTQGDWWFARHKATGRTGYIPSNYVAREKSIESQPWYFGKMRRIDAEKCLLHTLNEHGAFLVRDSESRQHDLSLSVREND-------SVKHYRIRQLD----HGG-----YFIARRRPFATLHDLIAHYQREADGLCVNLGAPCAKSEAPQTTTFTYDDQWEVDRRSVRLIRQ-IGAGQFGEVWEGRWNVNVPVAVKKLKAGTADPTDFLAEAQIMKKLRHPKLLSLYAVCTRDEPILIVTELMQE-NLLTFLQRRGRQC--QMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILINN----SLSVKIADFGLARILMKENEYEARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTEIVTF-GRLPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWRSDPDKRPTFETLQWKLEDLFN 494          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVK-SAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENR-EGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDE---FELDPAELKLNSTPIGKGQFGVVKKGEFRRM-PVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLL-DNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLY-VLMLECWQHDPKKRPAFEYVCQKIGDYL 2199
            ++A++ Y+   +  L  QKG+  +++D SN  WWYV+    G  GYVP N++ K  ++ + +WY   + R +AE ++L  +  +G FL+R+  +    + L++   D +  G   V HY    I+ L  D G     Y+++ +  F+++ +++ Y+     GL  +L  P  R   +P    +  D    +E+   +L L    +G G FG V  G++R +  VA+K M  G M+ + F+ EA+ M+  +HPNLV+L+ V  ++ P  IITEYM +GSL  +LR   S    +   L D+ AQ+A GM YLE    VHRDLAARN LV         VKVADFG+AR L+ +++YE   G KFP++W  PE      +T K+DVWS+G+L++E+ T   + PY G +N +V + +  G R+  P  CP+++Y  ++L+CW   P +RP F+ +     DY 
Sbjct:   20 LVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGG-TVKHYK---IKRLDHDQG-----YFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPR--LAPTRPDLSHDTQQNWEIPRNQLHLKRK-LGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQ--ALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMT-KGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYF 465          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVK-SAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENR-EGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLD---EFELDPAELKLNSTPIGKGQFGVVKKGEFRRM-PVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLL-DNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLY-VLMLECWQHDPKKRPAFEYVCQKIGDYL 2199
            ++A++ Y+   +  L  QKG+  +++D SN  WWYV+    G  GYVP N++ K  ++ + +WY   + R +AE ++L  +  +G FL+R+  +    + L++   D +  G   V HY    I+ L  D G     Y+++ +  F+++ +++ Y+     GL  +L  P  R   +P    +  D    +E+   +L L    +G G FG V  G++R +  VA+K M  G M+ + F+ EA+ M+  +HPNLV+L+ V  ++ P  IITEYM +GSL  +LR   S    +   L D+ AQ+A GM YLE    VHRDLAARN LV         VKVADFG+AR L+ +++YE   G KFP++W  PE      +T K+DVWS+G+L++E+ T   + PY G +N +V + +  G R+  P  CP+++Y  ++L+CW   P +RP F+ +     DY 
Sbjct:   76 LVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGG-TVKHYK---IKRLDHDQG-----YFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPR--LAPTRPDLSHDTQQNWEIPRNQLHLKRK-LGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQ--ALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMT-KGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYF 521          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVK-SAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENR-EGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLD---EFELDPAELKLNSTPIGKGQFGVVKKGEFRRM-PVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLL-DNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLY-VLMLECWQHDPKKRPAFEYVCQKIGDYL 2199
            ++A++ Y+   +  L  QKG+  +++D SN  WWYV+    G  GYVP N++ K  ++ + +WY   + R +AE ++L  +  +G FL+R+  +    + L++   D +  G   V HY    I+ L  D G     Y+++ +  F+++ +++ Y+     GL  +L  P  R   +P    +  D    +E+   +L L    +G G FG V  G++R +  VA+K M  G M+ + F+ EA+ M+  +HPNLV+L+ V  ++ P  IITEYM +GSL  +LR   S    +   L D+ AQ+A GM YLE    VHRDLAARN LV         VKVADFG+AR L+ +++YE   G KFP++W  PE      +T K+DVWS+G+L++E+ T   + PY G +N +V + +  G R+  P  CP+++Y  ++L+CW   P +RP F+ +     DY 
Sbjct:   76 LVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGG-TVKHYK---IKRLDHDQG-----YFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPR--LAPTRPDLSHDTQQNWEIPRNQLHLKRK-LGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQ--ALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMT-KGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYF 521          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVK-SAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENR-EGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLD---EFELDPAELKLNSTPIGKGQFGVVKKGEFRRM-PVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLL-DNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLY-VLMLECWQHDPKKRPAFEYVCQKIGDYL 2199
            ++A++ Y+   +  L  QKG+  +++D SN  WWYV+    G  GYVP N++ K  ++ + +WY   + R +AE ++L  +  +G FL+R+  +    + L++   D +  G   V HY    I+ L  D G     Y+++ +  F+++ +++ Y+     GL  +L  P  R   +P    +  D    +E+   +L L    +G G FG V  G++R +  VA+K M  G M+ + F+ EA+ M+  +HPNLV+L+ V  ++ P  IITEYM +GSL  +LR   S    +   L D+ AQ+A GM YLE    VHRDLAARN LV         VKVADFG+AR L+ +++YE   G KFP++W  PE      +T K+DVWS+G+L++E+ T   + PY G +N +V + +  G R+  P  CP+++Y  ++L+CW   P +RP F+ +     DY 
Sbjct:   80 LVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGG-TVKHYK---IKRLDHDQG-----YFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPR--LAPTRPDLSHDTQQNWEIPRNQLHLKRK-LGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQ--ALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMT-KGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYF 525          

Query:   85 LKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEK--VQDEDLDN---KKNVFQIAYVEDILSTNRN--------------------------ILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEA-------------SPPGPVDRR----NSSNTNGNFG--------ERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPT---ANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSD--KWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSL---TTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIG 2190
            +K   M KR+Q K  F+   YK + F LT     YF++    R +E+  + L  ++ VE+  V  E  D        FQ+ Y E   S N +                           LY++ANS  ER +WI  IR   +D       RYHPG+W    ++SCC  +SR + GC+ A             S P     R    NSS TN  F                    G  +   G   G      +   PQS+ +  +  PT    N ++L         T         P   N +  +NS   K V+A++ +  +    L L+K   Y V+D S   WW VK A G+ GY+P+NY+ KP +L     ++WY  D++RQ+AES+L + ++EGCF+VR S S K  YTLS+ +K P++     V HYH                 YYLSEKH  +TI D+I+YH+HNSGGL  RL+S P  D   P TAG+  D++E+ P EL L    +G GQFGVV++G++R  +  AVK M EG M+EDDFI+EAK M  L HPNLVQL+GV  K RPI I+TEYMKHGSL ++LR           +L D+C QV+KGM YLE  N++HRDLAARNCLV + +     VKVADFG+AR++LD+ Y  S GTKFP++WAPPEV   + ++ K+DVW++GVLMWE+FT C + PY    N++V + +  G  L KP  C   +Y +M  CW H P++RPAF  +  ++ 
Sbjct:   43 VKSGSMVKRAQNKKRFTPVNYKHRWFELTKRTFSYFDVENVERRRERGRIHLKGVRLVEEATVSGEGGDPFAPDGYPFQVGYCEISASANSHQLENGNGGGSGVGIEGQQSGRAVPQYTLYVIANSEKERSEWIRAIRQVCEDSNTPKSYRYHPGLWSGK-KWSCCKGLSRTTFGCRAAAHWREANNNPSNGSSPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIPT---------PGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYV-KPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKS-STKGLYTLSLHTKVPQS----HVKHYHIKQNARCE---------YYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPC-DRPVPPTAGLSHDKWEIHPMELMLMEE-LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSEN----VVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFT-CGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLA 778          

Query:   85 LKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEK--VQDEDLDN---KKNVFQIAYVEDILSTNRN--------------------------ILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEA-------------SPPGPVDRR----NSSNTNGNFG--------ERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPT---ANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSD--KWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSL---TTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIG 2190
            +K   M KR+Q K  F+   YK + F LT     YF++    R +E+  + L  ++ VE+  V  E  D        FQ+ Y E   S N +                           LY++ANS  ER +WI  IR   +D       RYHPG+W    ++SCC  +SR + GC+ A             S P     R    NSS TN  F                    G  +   G   G      +   PQS+ +  +  PT    N ++L         T         P   N +  +NS   K V+A++ +  +    L L+K   Y V+D S   WW VK A G+ GY+P+NY+ KP +L     ++WY  D++RQ+AES+L + ++EGCF+VR S S K  YTLS+ +K P++     V HYH                 YYLSEKH  +TI D+I+YH+HNSGGL  RL+S P  D   P TAG+  D++E+ P EL L    +G GQFGVV++G++R  +  AVK M EG M+EDDFI+EAK M  L HPNLVQL+GV  K RPI I+TEYMKHGSL ++LR           +L D+C QV+KGM YLE  N++HRDLAARNCLV + +     VKVADFG+AR++LD+ Y  S GTKFP++WAPPEV   + ++ K+DVW++GVLMWE+FT C + PY    N++V + +  G  L KP  C   +Y +M  CW H P++RPAF  +  ++ 
Sbjct:   43 VKSGSMVKRAQNKKRFTPVNYKHRWFELTKRTFSYFDVENVERRRERGRIHLKGVRLVEEATVSGEGGDPFAPDGYPFQVGYCEISASANSHQLENGNGGGSGVGIEGQQSGRAVPQYTLYVIANSEKERSEWIRAIRQVCEDSNTPKSYRYHPGLWSGK-KWSCCKGLSRTTFGCRAAAHWREANNNPSNGSSPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIPT---------PGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYV-KPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKS-STKGLYTLSLHTKVPQS----HVKHYHIKQNARCE---------YYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPC-DRPVPPTAGLSHDKWEIHPMELMLMEE-LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSEN----VVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFT-CGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLA 778          

Query:   85 LKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEK--VQDEDLDN---KKNVFQIAYVEDILSTNRN--------------------------ILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEA-------------SPPGPVDRR----NSSNTNGNFG--------ERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPT---ANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSD--KWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSL---TTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIG 2190
            +K   M KR+Q K  F+   YK + F LT     YF++    R +E+  + L  ++ VE+  V  E  D        FQ+ Y E   S N +                           LY++ANS  ER +WI  IR   +D       RYHPG+W    ++SCC  +SR + GC+ A             S P     R    NSS TN  F                    G  +   G   G      +   PQS+ +  +  PT    N ++L         T         P   N +  +NS   K V+A++ +  +    L L+K   Y V+D S   WW VK A G+ GY+P+NY+ KP +L     ++WY  D++RQ+AES+L + ++EGCF+VR S S K  YTLS+ +K P++     V HYH                 YYLSEKH  +TI D+I+YH+HNSGGL  RL+S P  D   P TAG+  D++E+ P EL L    +G GQFGVV++G++R  +  AVK M EG M+EDDFI+EAK M  L HPNLVQL+GV  K RPI I+TEYMKHGSL ++LR           +L D+C QV+KGM YLE  N++HRDLAARNCLV + +     VKVADFG+AR++LD+ Y  S GTKFP++WAPPEV   + ++ K+DVW++GVLMWE+FT C + PY    N++V + +  G  L KP  C   +Y +M  CW H P++RPAF  +  ++ 
Sbjct:   43 VKSGSMVKRAQNKKRFTPVNYKHRWFELTKRTFSYFDVENVERRRERGRIHLKGVRLVEEATVSGEGGDPFAPDGYPFQVGYCEISASANSHQLENGNGGGSGVGIEGQQSGRAVPQYTLYVIANSEKERSEWIRAIRQVCEDSNTPKSYRYHPGLWSGK-KWSCCKGLSRTTFGCRAAAHWREANNNPSNGSSPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIPT---------PGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYV-KPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKS-STKGLYTLSLHTKVPQS----HVKHYHIKQNARCE---------YYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPC-DRPVPPTAGLSHDKWEIHPMELMLMEE-LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSEN----VVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFT-CGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLA 778          

Query:  799 PAAINIEGDENSD--KWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLT---TFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIG 2190
            P   N +  +NS   K V+A++ +  +    L L+K   Y V+D S   WW VK A G+ GY+P+NY+ KP +L     ++WY  D++RQ+AES+L + ++EGCF+VR S S K  YTLS+ +K P++     V HYH                 YYLSEKH  +TI D+I+YH+HNSGGL  RL+S P  D   P TAG+  D++E+ P EL L    +G GQFGVV++G++R  +  AVK M EG M+EDDFI+EAK M  L HPNLVQL+GV  K RPI I+TEYMKHGSL ++LR           +L D+C QV+KGM YLE  N++HRDLAARNCLV + +     VKVADFG+AR++LD+ Y  S GTKFP++WAPPEV   + ++ K+DVW++GVLMWE+FT C + PY    N++V + +  G  L KP  C   +Y +M  CW H P++RPAF  +  ++ 
Sbjct:    8 PGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYV-KPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKS-STKGLYTLSLHTKVPQS----HVKHYHIKQ---------NARCEYYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPC-DRPVPPTAGLSHDKWEIHPMELMLMEE-LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSEN----VVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFT-CGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLA 456          

Query:  799 PAAINIEGDENSD--KWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTT---FDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIG 2190
            P   N +  +NS   K V+A++ +  +    L L+K   Y V+D S   WW VK A G+ GY+P+NY+ KP +L     ++WY  D++RQ+AES+L + ++EGCF+VR S S K  YTLS+ +K P++     V HYH                 YYLSEKH  +TI D+I+YH+HNSGGL  RL+S P  D   P TAG+  D++E+ P EL L    +G GQFGVV++G++R  +  AVK M EG M+EDDFI+EAK M  L HPNLVQL+GV  K RPI I+TEYMKHGSL ++LR           +L D+C QV+KGM YLE  N++HRDLAARNCLV + +     VKVADFG+AR++LD+ Y  S GTKFP++WAPPEV   + ++ K+DVW++GVLMWE+FT C + PY    N++V + +  G  L KP  C   +Y +M  CW H P++RPAF  +  ++ 
Sbjct:  109 PGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYV-KPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKS-STKGLYTLSLHTKVPQS----HVKHYHIKQNARCE---------YYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPC-DRPVPPTAGLSHDKWEIHPMELMLMEE-LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSEN----VVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFT-CGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLA 557          

Query:  826 ENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHK--PNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKL--KVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRD-HESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQ 2205
            E  ++ V+A+ N+ P     LPLQK E YF+VD S   WW VK   G+ G VP  Y+ +   N++  F+WY KD+ R +AE +L++EN++G F+VR+S      YT+S+ ++   + G+   +V HY       +         +YYL+EK+ F TI ++I YH+HN  GL+ RLR    R+   S     +  D++E+ P E+KL S  +G GQFG+V KG ++ M VAVK + EG M+E++F +EA+ M  L+H  LVQL+GVV ++ PI ++ E+M++G L +FLR +      +   L ++C  V++GMAYLE  NF+HRDLAARNCL   VS  SV VK+ADFGM RF+LD+ Y  S G+KFPVRW+ PEV +   Y+ K+DVWSFGV MWEV++     PY  ++NS+V + +  G RL KP +CP  +Y LM   W+  P+ RP+F  +  ++   LDQ
Sbjct:  165 EPEERIVVALRNFTPKEHTDLPLQKDEEYFIVDCSEPNWWTVKDKDGNVGSVPCIYVTEKLSNNIEKFEWYNKDINRTEAEDLLMQENKDGGFMVRNS-KHAGVYTVSIFTRVSGSNGEKCPQVKHYQ------IKVQSEGEKVLYYLAEKYLFPTIPELIRYHQHNPAGLITRLRHCVSRNVPNSARIKELSSDKWEIHPDEVKL-SVELGSGQFGLVWKGSWQDMEVAVKTVREGFMSEEEFKEEAQVMMKLSHNRLVQLYGVVTQRSPIYLVFEFMENGCLTEFLRAKKGKLSQK--ALLEMCLDVSEGMAYLESSNFIHRDLAARNCL---VSENSV-VKIADFGMTRFVLDDQYTSSHGSKFPVRWSSPEVIKFGKYSSKSDVWSFGVFMWEVYS-EGRTPYDNRSNSEVVETLNAGHRLLKPRLCPQSVYELMQWSWKEKPEDRPSFALLLHELA-CLDQ 614          

Query:  106 KRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLD---NKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQE-------ASPPGPVDRRNSSNTNGNFGERIVAA 603
            K+SQ+K   S   YK + F+L    L YFE   G +  +K  + L+ +K VE V+  D+    + K  FQI +       +   LY+ A     R  W+  ++   ++  + FL +YHP  W + G++ CC    + + GC E         PP P   R SS       ERIV A
Sbjct:   13 KKSQQKRRTSPCNYKERTFILNTQDLAYFEQRPGKKPTQKGCIELSHIKCVEIVRS-DVPIPCDYKYPFQIIH-------DSYYLYVFAPDNDCRLKWVKALKEAIQNN-SLFL-KYHPDFWGE-GKWRCCQQTEKLATGCSEYYPNGAKPLPPTPDPSRRSSEPE----ERIVVA 173          

Query:  826 ENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHK--PNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKL--KVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRD-HESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQ 2205
            E  ++ V+A+ N+ P     LPLQK E YF+VD S   WW VK   G+ G VP  Y+ +   N++  F+WY KD+ R +AE +L++EN++G F+VR+S      YT+S+ ++   + G+   +V HY       +         +YYL+EK+ F TI ++I YH+HN  GL+ RLR    R+   S     +  D++E+ P E+KL S  +G GQFG+V KG ++   VAVK + EG M+E++F +EA+ M  L+H  LVQL+GVV ++ PI ++ E+M++G L +FLR +      +   L ++C  V++GMAYLE  NF+HRDLAARNCL   VS  SV VK+ADFGM RF+LD+ Y  S G+KFPVRW+ PEV +   Y+ K+DVWSFGV MWEV++     PY  ++NS+V + +  G RL KP +CP  +Y LM   W+  P+ RP+F  +  ++   LDQ
Sbjct:  152 EPEERIVVALRNFIPKEHTDLPLQKDEEYFIVDCSEPNWWTVKDKDGNVGSVPCIYVTEKLSNNIEKFEWYNKDINRTEAEDLLMQENKDGGFMVRNS-KHAGVYTVSIFTRVSGSNGEKCPQVKHYQ------IKVQSEGEKVLYYLAEKYLFPTIPELIRYHQHNPAGLITRLRHCVSRNVPNSARIKELSSDKWEIHPDEVKL-SVELGSGQFGLVWKGSWQDREVAVKTVREGFMSEEEFKEEAQVMMKLSHNRLVQLYGVVTQRSPIYLVFEFMENGCLTEFLRAKKGKLSQK--ALLEMCLDVSEGMAYLESSNFIHRDLAARNCL---VSENSV-VKIADFGMTRFVLDDQYTSSHGSKFPVRWSSPEVIKFGKYSSKSDVWSFGVFMWEVYS-EGRTPYDNRSNSEVVETLNAGHRLLKPRLCPQSVYELMQWSWKEKPEDRPSFALLLHELA-CLDQ 601          

Query:  106 KRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQE-------ASPPGPVDRRNSSNTNGNFGERIVAA 603
            K+SQ+K   S   YK + F+L    L YFE   G+     C  + N LK                 ++ Y+  I+  +   LY+ A     R  W+  ++   ++  + FL +YHP  W + G++ CC    + + GC E         PP P   R SS       ERIV A
Sbjct:   13 KKSQQKRRTSPCNYKERTFILNTQDLAYFEQRPGDNFDRNC--IQNCLK----------------VELVYLVVIIIHDSYYLYVFAPDNDCRLKWVKALKEAIQNN-SLFL-KYHPDFWGE-GKWRCCQQTEKLATGCSEYYPNGAKPLPPTPDPSRRSSEPE----ERIVVA 160          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKP-NSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSK-DPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRS-PPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSI-YTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYL 2199
            VIA + Y P+  N L L+K E Y +++ S+  W+  K   G  GY+P+NYI +  N L  +DWY K++ R QAE++L  EN++G FLVRDS      YT+SV +K   E +G  +  HY+     +L+ADG      +YL+EKH F  I ++I+YH+HN+ GLV RL+     R   +P TAG+G   +E+DP +L      +G GQFGVVK G+++ R  VA+K + EG+M+EDDFI+EAK M  L H NLVQL+GV  K+RPI I+TEY+ +G L ++L+    +     + L ++C  V++GM YLE   F+HRDLAARNCLV +    +  +KV DFG++R++LD+ Y  S G+KFPVRW+PPEV     ++ K+D+W+FGVLMWE++T     PY   NN+++ + I  G RL +P +  + ++ +M  CW   P +RP F+ +   I D L
Sbjct:  197 VIAEYEYAPMTTNDLELRKDEEYTLLEISDPNWFKAKDKYGKEGYIPSNYIVQALNGLEKYDWYCKNINRSQAENLLKTENKDGGFLVRDSGKFTGKYTVSVFTKAGGETSGSCR--HYNI----LLTADG-----QFYLAEKHNFTNIPELINYHQHNAAGLVSRLKYIVSNRAQNAPCTAGLGYGSWEIDPRQLTF-IRELGNGQFGVVKYGKWQGRHDVAIKMVKEGSMSEDDFIEEAKVMMKLCHGNLVQLYGVCTKQRPIYIVTEYLANGCLLNYLQEGLLN--PTSIALLEMCKDVSEGMKYLEANQFIHRDLAARNCLVDS----NGTIKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLLYCKFSSKSDIWAFGVLMWEIYT-QGRMPYDRWNNTEIVEKISAGHRLYRPQMANENVFAIMNSCWHERPDERPTFQELVGVIKDLL 634          

Query:  826 ENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHK--PNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKL--KVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRD-HESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQH 2142
            E  ++ V+A+ N+ P     LPLQK E YF+VD S   WW VK   G+ G VP  Y+ +   N++  F+WY KD+ R +AE +L++EN++G F+VR+S      YT+S+ ++   + G+   +V HY       +         +YYL+EK+ F TI ++I YH+HN  GL+ RLR    R+   S     +  D++E+ P E+KL S  +G GQFG+V KG ++   VAVK + EG M+E++F +EA+ M  L+H  LVQL+GVV ++ PI ++ E+M++G L +FLR +      +   L ++C  V++GMAYLE  NF+HRDLAARNCL   VS  SV VK+ADFGM RF+LD+ Y  S G+KFPVRW+ PEV +   Y+ K+DVWSFGV MWEV++     PY  ++NS+V + +  G RL KP +CP  +Y LM   W+ 
Sbjct:  149 EPEERIVVALRNFIPKEHTDLPLQKDEEYFIVDCSEPNWWTVKDKDGNVGSVPCIYVTEKLSNNIEKFEWYNKDINRTEAEDLLMQENKDGGFMVRNS-KHAGVYTVSIFTRVSGSNGEKCPQVKHYQ------IKVQSEGEKVLYYLAEKYLFPTIPELIRYHQHNPAGLITRLRHCVSRNVPNSARIKELSSDKWEIHPDEVKL-SVELGSGQFGLVWKGSWQDREVAVKTVREGFMSEEEFKEEAQVMMKLSHNRLVQLYGVVTQRSPIYLVFEFMENGCLTEFLRAKKGKLSQK--ALLEMCLDVSEGMAYLESSNFIHRDLAARNCL---VSENSV-VKIADFGMTRFVLDDQYTSSHGSKFPVRWSSPEVIKFGKYSSKSDVWSFGVFMWEVYS-EGRTPYDNRSNSEVVETLNAGHRLLKPRLCPQSVYELMQWSWKE 578          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSK-DPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRS-PPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSI-YTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYL 2199
            VIA + Y P+  N L L+K E Y +++ S+  W+  K   G                    WY K++ R QAE++L  EN++G FLVRDS      YT+SV +K   E +G  +  HY+     +L+ADG      +YL+EKH F  I ++I+YH+HN+ GLV RL+     R   +P TAG+G   +E+DP +L      +G GQFGVVK G+++ R  VA+K + EG+M+EDDFI+EAK M  L H NLVQL+GV  K+RPI I+TEY+ +G L ++L+ R S+     +VL ++C  V++GM YLE   F+HRDLAARNCLV +    +  +KV DFG++R++LD+ Y  S G+KFPVRW+PPEV     ++ K+D+W+FGVLMWE++T     PY   NN+++ + I  G RL +P +  + ++ +M  CW   P +RP F+ + + I D L
Sbjct:  197 VIAEYEYAPMTTNDLELRKDEEYTLLEISDPNWFKAKDKYG--------------------WYCKNINRSQAENLLKTENKDGGFLVRDSGKFTGKYTVSVFTKAGGETSGSCR--HYNI----LLTADG-----QFYLAEKHNFTNIPELINYHQHNAAGLVSRLKYIVSNRAQNAPCTAGLGYGSWEIDPRQLTF-IRELGNGQFGVVKYGKWQGRHDVAIKMVKEGSMSEDDFIEEAKVMMKLCHGNLVQLYGVCTKQRPIYIVTEYLANGCLLNYLQERLSN--PTSIVLLEMCKDVSEGMKYLEANQFIHRDLAARNCLVDS----NGTIKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLLYCKFSSKSDIWAFGVLMWEIYT-QGRMPYDRWNNTEIVEKISAGHRLYRPQMANENVFAIMNSCWHERPDERPTFKELVEVIKDLL 613          

Query:  829 NSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHES-PVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLD 2202
            N ++ VIA+ +++PV  + L L  GE YFV++  ++ WW  ++  G  GY+P+NY+   K ++L  ++WY +++ R +AE +L  E++EG F+VR+S S+   YT+S+ +K     G   + HYH    +            YYL+EKH F TI ++I YHKHN+ GLV RLR P    ++S P TAG   D++E++P+EL      +G G FGVV+ G++R +  VA+K + EGAM+E+DFI+EAK M  L H  LVQL+GV  ++RPI I+TE+M+HG L ++LR R   +   P +L  +C  V + M+YLE  NF+HRDLAARNCLV         VKV+DFGM R++LD+ Y  S G KFPV+W+PPEVF  S ++ K+DVWSFGVLMWEVFT   + P+   +N +V + +  G RL +P +    +Y +M+ CW   P+ RP F  + ++IG  L+
Sbjct:  166 NGEETVIAMFDFHPVEPHDLRLVTGEEYFVLEKKDAHWWKARNTYGQQGYIPSNYVTEKKLDNLYQYEWYSRNMNRSKAEQLLKSEDKEGGFIVRNS-SQAGLYTVSLYTKYG-GEGSTCIRHYHIKETQYPKK--------YYLAEKHVFNTIPEMIEYHKHNAAGLVTRLRYPVCSKNKSAPTTAGFSYDKWEINPSELTFMKE-LGSGLFGVVRLGKWRAQYKVAIKAIREGAMSEEDFIEEAKVMMKLTHLKLVQLYGVCTQQRPIYIVTEFMEHGCLLNYLRQRHGQF--SPDILLSMCQDVCEAMSYLEQNNFIHRDLAARNCLVNDAG----VVKVSDFGMTRYVLDDQYTSSCGAKFPVKWSPPEVFNYSRFSSKSDVWSFGVLMWEVFT-EGKMPFESYSNVEVVEMVTRGERLYRPKLATKIIYSVMVACWHEKPEGRPKFFDLMKQIGLILE 610          

Query:  829 NSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPM-RDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLD 2202
            N ++ VIA+ +++PV  + L L  GE YFV++  ++ WW  ++  G  GY+P+NY+   K ++L  ++WY +++ R +AE +L  E++EG F+VR+S S+   YT+S+ +K     G   + HYH    +            YYL+EKH F TI ++I YHKHN+ GLV RLR P   ++  +P TAG   D++E++P+EL      +G G FGVV+ G++R +  VA+K + EGAM+E+DFI+EAK M  L H  LVQL+GV  ++RPI I+TE+M+HG L ++LR R   +   P +L  +C  V + M+YLE  NF+HRDLAARNCLV         VKV+DFGM R++LD+ Y  S G KFPV+W+PPEVF  S ++ K+DVWSFGVLMWEVFT   + P+   +N +V + +  G RL +P +    +Y +M+ CW   P+ RP F  + ++IG  L+
Sbjct:  194 NGEETVIAMFDFHPVEPHDLRLVTGEEYFVLEKKDAHWWKARNTYGQQGYIPSNYVTEKKLDNLYQYEWYSRNMNRSKAEQLLKSEDKEGGFIVRNS-SQAGLYTVSLYTKYG-GEGSTCIRHYHIKETQYPKK--------YYLAEKHVFNTIPEMIEYHKHNAAGLVTRLRYPVCSKNKSAPTTAGFSYDKWEINPSELTFMKE-LGSGLFGVVRLGKWRAQYKVAIKAIREGAMSEEDFIEEAKVMMKLTHLKLVQLYGVCTQQRPIYIVTEFMEHGCLLNYLRQRHGQF--SPDILLSMCQDVCEAMSYLEQNNFIHRDLAARNCLVNDAG----VVKVSDFGMTRYVLDDQYTSSCGAKFPVKWSPPEVFNYSRFSSKSDVWSFGVLMWEVFT-EGKMPFESYSNVEVVEMVTRGERLYRPKLATKIIYSVMVACWHEKPEGRPKFFDLMKQIGLILE 638          

Query:  100 MCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQD--EDLDNK-KNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRR 555
            + KRSQ+K   S   YK + FVLT + L Y+E     + K K ++ +  +K VE V++  E++  + K  FQI Y         N LY+ A +A  R  W+ LI+   K+  +  + +YHP  W   G Y CC    + + GC+E +  G + ++
Sbjct:   24 LIKRSQQKKRTSPLNYKERVFVLTKSRLTYYEGRPEKKNK-KGSVDITKVKCVEFVKNGSENIPCQYKYAFQIVY-------ESNTLYVFAPTAESRFKWVKLIKEEVKNN-SFIMSKYHPQFWAD-GVYQCCRQTEKLAPGCEEYNLFGDITKK 168          

Query:  100 MCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQD--EDLDNK-KNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPM-RDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLD 2202
            + KRSQ+K   S   YK + FVLT + L Y+E     + K K ++ +  +K VE V++  E++  + K  FQI Y         N LY+ A +A  R  W+ LI+   K+  +  + +YHP  W   G Y C          C++     P                           G E       N   +I++ P           PT ++  ++ I  S+    T +     P   + E ++N ++ VIA+ +++PV  + L L  GE YFV++  ++ WW  ++  G  GY+P  +  + N++   +    D              +EG F+VR+S S+   YT+S+ +K     G   + HYH    +            YYL+EKH F TI ++I YHKHN+ GLV RLR P   ++  +P TAG   D++E++P+EL      +G G FGVV+ G++R +  VA+K + EGAM+E+DFI+EAK M  L H  LVQL+GV  ++RPI I+TE+M+HG L ++LR R   +   P +L  +C  V + M+YLE  NF+HRDLAARNCLV         VKV+DFGM R++LD+ Y  S G KFPV+W+PPEVF  S ++ K+DVWSFGVLMWEVFT   + P+   +N +V + +  G RL +P +    +Y +M+ CW   P+ RP F  + ++IG  L+
Sbjct:   11 LIKRSQQKKRTSPLNYKERVFVLTKSRLTYYEGRPEKKNK-KGSVDITKVKCVEFVKNGSENIPCQYKYAFQIVY-------ESNTLYVFAPTAESRFKWVKLIKEEVKNN-SFIMSKYHPQFWAD-GVYQC----------CRQTEKLAP---------------------------GCEEY-----NLFGDITKKPLP---------PTPDAIRVRIIQVSK----TWIARPPPPRPPDPEPEDNGEETVIAMFDFHPVEPHDLRLVTGEEYFVLEKKDAHWWKARNTYGQQGYIPICFNIEHNTMIICNNTSSD--------------KEGGFIVRNS-SQAGLYTVSLYTKYG-GEGSTCIRHYHIKETQYPKK--------YYLAEKHVFNTIPEMIEYHKHNAAGLVTRLRYPVCSKNKSAPTTAGFSYDKWEINPSELTFMKE-LGSGLFGVVRLGKWRAQYKVAIKAIREGAMSEEDFIEEAKVMMKLTHLKLVQLYGVCTQQRPIYIVTEFMEHGCLLNYLRQRHGQF--SPDILLSMCQDVCEAMSYLEQNNFIHRDLAARNCLVNDAG----VVKVSDFGMTRYVLDDQYTSSCGAKFPVKWSPPEVFNYSRFSSKSDVWSFGVLMWEVFT-EGKMPFESYSNVEVVEMVTRGERLYRPKLATKIIYSVMVACWHEKPEGRPKFFDLMKQIGLILE 620          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVD-SSNSQWWYVKSAAGDAGYVPTNYIHKP-NSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHES-PVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSI-YTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQN 2208
            V+A++++ P+    LPL KGE Y +++  + + W   +   G  GY+P NY+ +  + L  ++WY K++TR QAE +L  E++EG F+VRDS SK   YT+SV +K   ++G+  + HY             AP   YYL+EKH + +I ++I YH+HN+ GL+ RL+ P     ++ P TAG+G   +E+DP +L      +G GQFGVVK G++R +  VA+K + EG+M+ED+FI+EAK M  L+H NLVQL+GV  K+RPI IITE++ +G L ++L++           L  +C+ V   M YLE + ++HRDLAARNCLV         VKV+DFG++R++LD+ Y  S G+KFPVRW+ PEV     ++ K+DVWSFGVLMWEVFT     PY    N+++ + I  G RL +P    DR+Y +M+ CW      RP F  +   I + L+ +
Sbjct:  211 VVAMYDFTPLNAQDLPLHKGEEYVLLEEGTGNPWLRARDKNGLEGYIPGNYVTEAQDPLEIYEWYSKNMTRSQAEKLLRAEDKEGGFIVRDS-SKAGKYTVSVYAK---SSGEGIIRHYVVCE---------APGNQYYLAEKHLYSSIPELITYHQHNAAGLISRLKYPVCSLRKTAPSTAGLGYGSWEIDPKDLTF-LKELGNGQFGVVKYGKWRGQHDVAIKMIKEGSMSEDEFIEEAKCMMKLSHQNLVQLYGVCTKQRPIFIITEFLSNGCLLNYLKDLRGRVSQGD--LLSMCSDVCAAMTYLESKQYLHRDLAARNCLVAA----DGIVKVSDFGLSRYVLDDEYTSSLGSKFPVRWSSPEVLLYCRFSSKSDVWSFGVLMWEVFT-LGRMPYDRFTNNEIVEQITRGVRLYRPQNATDRVYSIMVSCWAEKADDRPTFRILHNTILEVLEDS 649          

Query:  859 NYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPM-RDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLD 2202
            +++PV  + L L  GE YFV++  ++ WW    A    GY   N                              ++EG F+VR+S S+   YT+S+ +K     G   + HYH    +            YYL+EKH F TI ++I YHKHN+ GLV RLR P   ++  +P TAG   D++E++P+EL      +G G FGVV+ G++R +  VA+K + EGAM+E+DFI+EAK M  L H  LVQL+GV  ++RPI I+TE+M+HG L ++LR R   +   P +L  +C  V + M+YLE  NF+HRDLAARNCLV         VKV+DFGM R++LD+ Y  S G KFPV+W+PPEVF  S ++ K+DVWSFGVLMWEVFT   + P+   +N +V + +  G RL +P +    +Y +M+ CW   P+ RP F  + ++IG  L+
Sbjct:    3 DFHPVEPHDLRLVTGEEYFVLEKKDAHWW---KARNTYGYTDAN------------------------------DKEGGFIVRNS-SQAGLYTVSLYTKYG-GEGSTCIRHYHIKETQYPKK--------YYLAEKHVFNTIPEMIEYHKHNAAGLVTRLRYPVCSKNKSAPTTAGFSYDKWEINPSELTFMK-ELGSGLFGVVRLGKWRAQYKVAIKAIREGAMSEEDFIEEAKVMMKLTHLKLVQLYGVCTQQRPIYIVTEFMEHGCLLNYLRQRHGQF--SPDILLSMCQDVCEAMSYLEQNNFIHRDLAARNCLVNDAG----VVKVSDFGMTRYVLDDQYTSSCGAKFPVKWSPPEVFNYSRFSSKSDVWSFGVLMWEVFT-EGKMPFESYSNVEVVEMVTRGERLYRPKLATKIIYSVMVACWHEKPEGRPKFFDLMKQIGLILE 402          

Query:   94 SRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFE--ISGGNRGKEKCTLLLNFLKFVEKVQDED-----------LDNKKNVFQIAYVEDI-----LSTNRNILYIVANSAAERDDWI----NLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKP-NSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSK---DPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHE-SPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQN 2208
            S   KRSQ+K   S   +K + F+LT   L Y+E     G RG +K ++ +  +  VE V  E             +    + QI+ +E       +  +   LY+ + +   R  WI    N+IRY +       + +YHP  W   G+Y CC   ++ +MGCQ              N NG+                        G++H    +  P +        P  +  + +P+               +P A  I   E   K V+A+++Y P+  N L L+KGE YF+++ SN  WW  +   G  GY+P+NYI +  +S+  ++WY K +TR QAE +L +E +EG F+VRDS SK   YT+SV +K   +P+      + HY              P   YYL+EKH F TI ++I+YH+HNS GL+ RL+ P  + ++ +P TAG+G   +E+DP +L      +G GQFGVVK G++R +  VA+K + EG+M+ED+FI+EAK M  L+H  LVQL+GV  K+RPI IITEYM +G L ++LR     +  +   L ++C  V + M YLE + F+HRDLAARNCLV         VKV+DFG++R++LD+ Y  S G+KFPVRW+PPEV   S ++ K+D+W+FGVLMWE+++   + PY    NS+  ++I  G RL +P +  +R+Y +M  CW     +RP+F+ +   I D +D+ 
Sbjct:    8 SIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVIPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNS-----DLVQKYHPCFWID-GQYLCCSQTAKNAMGCQILE-----------NRNGSLKP---------------------GSSHRKTKKPLPPT--------PEEDQILKKPLPP-------------EPTAAPISTTEL--KKVVALYDYMPMNANDLQLRKGEEYFILEESNLPWWRARDKNGQEGYIPSNYITEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGEPQGV----IRHY---------VVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSKQNKNAPSTAGLGYGSWEIDPKDLTFLKE-LGTGQFGVVKYGKWRGQYDVAIKMIREGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG----VVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYS-LGKMPYERFTNSETAEHIAQGLRLYRPHLASERVYTIMYSCWHEKADERPSFKILLSNILDVMDEE 658          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSP-PMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCE 2214
            V+A++++     + L L++G+ Y +++ ++  WW  +   G  GY+P+NY+   K N+L  ++WY ++  R +AE +L  E++EG F+VRDS S+   YT+S+ +K     G     HYH      +     +P   YYL+EKHAF +I ++I YHKHN+ GLV RLR P   +   +P TAG   D++E++P+EL      +G G FGVV+ G++R +  VA+K + EGAM E+DFI+EAK M  L HP LVQL+GV  +++PI I+TE+M+ G L +FLR R   +F+R ++L+ +C  V +GM YLE  +F+HRDLAARNCLV         VKV+DFGMAR++LD+ Y  S+G KFPV+W PPEVF  S ++ K+DVWSFGVLMWE+FT     P+    N +V   +  G RL +P +    LY +ML CWQ  P+ RP+FE + + I + ++  CE
Sbjct:  183 VVAMYDFQATEAHDLRLERGQEYIILEKNDLHWWRARDKYGSEGYIPSNYVTGKKSNNLDQYEWYCRNTNRSKAEQLLRTEDKEGGFMVRDS-SQPGLYTVSLYTKFG-GEGSSGFRHYH------IKETATSPK-KYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTF-MRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQG-HFSRDMLLS-MCQDVCEGMEYLERNSFIHRDLAARNCLVNEAG----VVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFT-EGRMPFEKNTNYEVVTMVTRGHRLHRPKLASKYLYEVMLRCWQERPEGRPSFEDLLRTIDELVE--CE 625          

Query:  100 MCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDED-LDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQ-----EAS-----PPGP 543
            + KRSQ+K   S   YK + FVLT + L Y+E     +   K  + ++ +K VE V+++D +   +N F    V D      N LYI A S   RD W+  ++   K+     + +YHP  W   G Y CC    + + GC+     E+S     PP P
Sbjct:   11 LIKRSQQKKKTSPLNYKERLFVLTKSVLSYYE-GRAEKKYRKGVIDISKIKCVEIVKNDDGVIPCQNKFPFQVVHDA-----NTLYIFAPSPQSRDRWVKKLKEEIKNN-NNIMIKYHPKFWAD-GSYQCCRQTEKLAPGCEKYNLFESSIRKTLPPAP 161          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSP-PMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCE 2214
            V+A++++     + L L++G+ Y +++ ++  WW  +   G  GY+P+NY+   K N+L  ++WY ++  R +AE +L  E++EG F+VRDS S+   YT+S+ +K     G     HYH      +     +P   YYL+EKHAF +I ++I YHKHN+ GLV RLR P   +   +P TAG   D++E++P+EL      +G G FGVV+ G++R +  VA+K + EGAM E+DFI+EAK M  L HP LVQL+GV  +++PI I+TE+M+ G L +FLR R   +F+R ++L+ +C  V +GM YLE  +F+HRDLAARNCLV         VKV+DFGMAR++LD+ Y  S+G KFPV+W PPEVF  S ++ K+DVWSFGVLMWE+FT     P+    N +V   +  G RL +P +    LY +ML CWQ  P+ RP+FE + + I + ++  CE
Sbjct:  183 VVAMYDFQATEAHDLRLERGQEYIILEKNDLHWWRARDKYGSEGYIPSNYVTGKKSNNLDQYEWYCRNTNRSKAEQLLRTEDKEGGFMVRDS-SQPGLYTVSLYTKFG-GEGSSGFRHYH------IKETATSPK-KYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTF-MRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQG-HFSRDMLLS-MCQDVCEGMEYLERNSFIHRDLAARNCLVNEAG----VVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFT-EGRMPFEKNTNYEVVTMVTRGHRLHRPKLASKYLYEVMLRCWQERPEGRPSFEDLLRTIDELVE--CE 625          

Query:  100 MCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDED-LDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQ-----EAS-----PPGP 543
            + KRSQ+K   S   YK + FVLT + L Y+E     +   K  + ++ +K VE V+++D +   +N F    V D      N LYI A S   RD W+  ++   K+     + +YHP  W   G Y CC    + + GC+     E+S     PP P
Sbjct:   11 LIKRSQQKKKTSPLNYKERLFVLTKSVLSYYE-GRAEKKYRKGVIDISKIKCVEIVKNDDGVIPCQNKFPFQVVHDA-----NTLYIFAPSPQSRDRWVKKLKEEIKNN-NNIMIKYHPKFWAD-GSYQCCRQTEKLAPGCEKYNLFESSIRKTLPPAP 161          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSP-PMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGD 2193
            V A++++ P     L L++ E Y +++  +  WW  +   G+ G +P+NY+  ++  +L  ++WY+K++TR Q E +L +E +EG F+VRDS     +YT+SV ++   +  +  + HY     ++   D G     +Y++E+H F ++ ++I YH++N+ GL+ RLR P  +     P T+G   +++E+DP+EL      IG GQFGVV  GE+R  +PVA+K + EG+M+E+DFI+EAK M  L+H  LVQL+GV ++++P+ I+TE+M++G L D+LR R      +  +L  +C  + +GMAYLE   ++HRDLAARNCLV +    +  VK++DFGMAR++LD+ Y  S+G KFPV+W PPEVF  + Y+ K+DVWSFGVLMWEVFT   + P+  K+N QV + I  G RL +P + P  +Y +M  CW   PK RP F  + Q + +
Sbjct:   33 VKALYDFLPREPGNLALKRAEEYLILERCDPHWWKARDRFGNEGLIPSNYVTENRLANLEIYEWYHKNITRNQTERLLRQEAKEGAFIVRDS-RHLGSYTISVFTRARRHT-QSSIKHY-----QIKKNDSG----QWYITERHLFPSVPELIQYHQYNAAGLISRLRYPIGLLGSCLPATSGFSYEKWEIDPSELAF-VKEIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERKGQL--QKALLLSMCQDICEGMAYLERSCYIHRDLAARNCLVSS----ACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFT-EGKMPFENKSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTE 468          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSP-PMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGD 2193
            V A++++ P     L L++ E Y +++  +  WW  +   G+ G +P+NY+  ++  +L  ++WY+K++TR Q E +L +E +EG F+VRDS     +YT+SV ++   +  +  + HY     ++   D G     +Y++E+H F ++ ++I YH++N+ GL+ RLR P  +     P T+G   +++E+DP+EL      IG GQFGVV  GE+R  +PVA+K + EG+M+E+DFI+EAK M  L+H  LVQL+GV ++++P+ I+TE+M++G L D+LR R      +  +L  +C  + +GMAYLE   ++HRDLAARNCLV +    +  VK++DFGMAR++LD+ Y  S+G KFPV+W PPEVF  + Y+ K+DVWSFGVLMWEVFT   + P+  K+N QV + I  G RL +P + P  +Y +M  CW   PK RP F  + Q + +
Sbjct:   87 VKALYDFLPREPGNLALKRAEEYLILERCDPHWWKARDRFGNEGLIPSNYVTENRLANLEIYEWYHKNITRNQTERLLRQEAKEGAFIVRDS-RHLGSYTISVFTRARRHT-QSSIKHY-----QIKKNDSG----QWYITERHLFPSVPELIQYHQYNAAGLISRLRYPIGLLGSCLPATSGFSYEKWEIDPSELAF-VKEIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERKGQL--QKALLLSMCQDICEGMAYLERSCYIHRDLAARNCLVSS----ACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFT-EGKMPFENKSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTE 522          

Query:   85 LKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEK--VQDEDLDN---KKNVFQIAYVEDILSTNRN--------------------------ILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEA-------------SPPGPVDRR----NSSNTNGNFG--------ERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPT---ANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSD--KWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSL---TTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIG 2190
            +K   M KR+Q K  F+   YK + F LT     YF++    R +E+  + L  ++ VE+  V  E  D        FQ+ Y E   S N +                           LY++ANS  ER +WI  IR   +D       RYHPG+W    ++SCC  +SR + GC+ A             S P     R    NSS TN  F                    G  +   G   G      +   PQS+ +  +  PT    N ++L         T         P   N +  +NS   K V+A++ +  +    L L+K   Y V+D S   WW VK A G+ GY+P+NY+ KP +L     ++WY  D++RQ+AES+L + ++EGCF+VR S S K  YTLS+ +K P++     V HYH                 YYLSEKH  +TI D+I+YH+HNSGGL  RL+S P  D   P TAG+  D++E+ P EL L    +G GQFGVV++G++R  +  AVK M EG M+EDDFI+EAK M  L HPNLVQL+GV  K RPI I+TEYMKHGSL ++LR           +L D+C QV+KGM YLE  N++HRDLAARNCLV + +     VKVADFG+AR++LD+ Y  S GTKFP++WAPPEV   + ++ K+DVW++GVLMWE+FT C + PY    N++V + +  G  L KP  C   +Y +M  CW H P++RPAF  +  ++ 
Sbjct:   43 VKSGSMVKRAQNKKRFTPVNYKHRWFELTKRTFSYFDVENVERRRERGRIHLKGVRLVEEATVSGEGGDPFAPDGYPFQVGYCEISASANSHQLENGNGGGSGVGIEGQQSGRAVPQYTLYVIANSEKERSEWIRAIRQVCEDSNTPKSYRYHPGLWSGK-KWSCCKGLSRTTFGCRAAAHWREANNNPSNGSSPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIPT---------PGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYV-KPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKS-STKGLYTLSLHTKVPQS----HVKHYHIKQNARCE---------YYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPC-DRPVPPTAGLSHDKWEIHPMELMLMEE-LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSEN----VVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFT-CGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLA 778          

Query:   94 SRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFE--ISGGNRGKEKCTLLLNFLKFVEKVQDED----------LDNKKNVFQIAYVEDI-----LSTNRNILYIVANSAAERDDWI----NLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI-HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSK---DPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHES-PVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEV-FQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQ 2205
            S   KRSQ+K   S   +K + F+LT + L Y+E     G RG +K ++ +  +  VE V  E+               N+ QI+ +E       +  +   LY+ + +   R  WI    ++IRY +       + +YHP  W   G+Y CC   ++ +MGC+       ++ RN S   G    R     L                         P+ +T V + +P   +    P  A + K                         V+A++NY P+    L LQKGE Y +++ S+  WW  +   G  GY+P+NY+    NSL  ++WY K++TR QAE +L +E +EG F+VRDS SK   YT+SV +K   DP+      + HY      V+      P   YYL+EKH F TI ++I YH+HNS GL+ RL+ P  R  +S P TAG+G   +E+DP +L      +G GQFGVVK G++R +  VA+K + EG+M+ED+FIDEAK M  L+H  LVQL+GV  K+RPI IITEYM +G L +FLR     +  +P  L ++C  V + M YLE + F+HRDLAARNCLV         VKV+DFG++R++LD+ Y  S G+KFPVRW+PPEV   S ++ K+DVWSFGVLMWEV++   + PY   NNS+  +++I G RL +P    +R+Y +M  CW    ++RP F  +   I D  D+
Sbjct:    8 SIFLKRSQQKKKTSPLNFKKRLFLLTESKLSYYEYDFERGRRGSKKGSVDIEKITCVETVVPENNPPPERQVPKKGEDYNMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKSVIRYNSD-----LVQKYHPCFWID-GQYLCCSQTAKNAMGCK------ILESRNGSLKAGR-SHRKTKKPLPPT----------------------PEEDTMVMKPLPPEPA----PSAAGEMKK------------------------VVALYNYVPMNVQDLQLQKGEDYLILEESHLPWWKARDKNGREGYIPSNYVTATSNSLEIYEWYSKNITRSQAEQLLKQEGKEGGFIVRDSTSKTGKYTVSVYAKSAVDPQGM----IRHY------VVCC---TPQNQYYLAEKHLFNTIPELITYHQHNSAGLISRLKYPVSRHQKSAPSTAGLGYGSWEIDPKDLTFLKE-LGTGQFGVVKYGKWRGQYNVAIKMIREGSMSEDEFIDEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNFLRETQRRF--QPAELLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG----IVKVSDFGLSRYVLDDEYTSSMGSKFPVRWSPPEVLLYSKFSSKSDVWSFGVLMWEVYS-LGKMPYERFNNSETTEHVIQGLRLYRPQQASERVYAIMYSCWHEKAEERPTFSALLGSIVDITDE 655          

Query:   94 SRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFE--ISGGNRGKEKCTLLLNFLKFVEKVQDED-----------LDNKKNVFQIAYVEDI-----LSTNRNILYIVANSAAERDDWI----NLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKP-NSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSK---DPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSP-PMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQ 2205
            S   KRSQ+K   S   +K + F+LT   L Y+E     G RG +K ++ +  +  VE V  E             +    + QI+ +E       +  +   LY+ + +   R  WI    N+IRY +       + +YHP  W   G+Y CC   ++ +MGCQ              N NG+                        G++H    +  P          PT     +             V+ S+              K V+A+++Y P+  N L L+KG+ YF+++ SN  WW  +   G  GY+P+NY+ +  +S+  ++WY K +TR QAE +L +E +EG F+VRDS SK   YT+SV +K   DP+      + HY              P   YYL+EKH F TI ++I+YH+HNS GL+ RL+ P   ++  +P TAG+G   +E+DP +L      +G GQFGVVK G++R +  VA+K + EG+M+ED+FI+EAK M  L+H  LVQL+GV  K+RPI IITEYM +G L ++LR     +  +   L ++C  V + M YLE + F+HRDLAARNCLV         VKV+DFG++R++LD+ Y  S G+KFPVRW+PPEV   S ++ K+D+W+FGVLMWE+++   + PY    NS+  ++I  G RL +P +  +++Y +M  CW     +RP F+ +   I D +D+
Sbjct:    8 SIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNS-----DLVQKYHPCFWID-GQYLCCSQTAKNAMGCQILE-----------NRNGSLKP---------------------GSSHRKTKKPLP----------PTPEEDQILKKPLPPEPAAAPVSTSEL-------------KKVVALYDYMPMNANDLQLRKGDEYFILEESNLPWWRARDKNGQEGYIPSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGDPQGV----IRHY---------VVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGSWEIDPKDLTFLKE-LGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG----VVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYS-LGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDE 657          

Query:  301 FQIAYVEDILSTNRNILYIVANSAAERDDWI----NLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKP-NSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSK---DPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHE-SPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQN 2208
            FQ+ Y E         LY+ + +   R  WI    N+IRY +       + +YHP  W   G+Y CC   ++ +MGCQ              N NG+                        G++H    +  P +        P  +  + +P+               +P A  I   E   K V+A+++Y P+  N L L+KGE YF+++ SN  WW  +   G  GY+P+NYI +  +S+  ++WY K +TR QAE +L +E +EG F+VRDS SK   YT+SV +K   +P+      + HY              P   YYL+EKH F TI ++I+YH+HNS GL+ RL+ P  + ++ +P TAG+G   +E+DP +L      +G GQFGVVK G++R +  VA+K + EG+M+ED+FI+EAK M  L+H  LVQL+GV  K+RPI IITEYM +G L ++LR     +  +   L ++C  V + M YLE + F+HRDLAARNCLV         VKV+DFG++R++LD+ Y  S G+KFPVRW+PPEV   S ++ K+D+W+FGVLMWE+++   + PY    NS+  ++I  G RL +P +  +R+Y +M  CW     +RP+F+ +   I D +D+ 
Sbjct:  102 FQVVYDE-------GPLYVFSPTEELRKRWIHQLKNVIRYNS-----DLVQKYHPCFWID-GQYLCCSQTAKNAMGCQILE-----------NRNGSLKP---------------------GSSHRKTKKPLPPT--------PEEDQILKKPLPP-------------EPTAAPISTTEL--KKVVALYDYMPMNANDLQLRKGEEYFILEESNLPWWRARDKNGQEGYIPSNYITEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGEPQGV----IRHY---------VVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSKQNKNAPSTAGLGYGSWEIDPKDLTFLKE-LGTGQFGVVKYGKWRGQYDVAIKMIREGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG----VVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYS-LGKMPYERFTNSETAEHIAQGLRLYRPHLASERVYTIMYSCWHEKADERPSFKILLSNILDVMDEE 658          

Query:  826 ENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSP-PMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCE 2214
            +NS++ V+A++++     + L L++G+ Y +++ ++  WW  +   G+ GY+P+NY+   K N+L  ++WY +++ R +AE +L  E++EG F+VRDS S+   YT+S+ +K     G     HYH            +P   YYL+EKHAF +I ++I YHKHN+ GLV RLR P  ++   +P TAG   +++E++P+EL      +G G FGVV+ G++R +  VA+K + EGAM E+DFI+EAK M  L HP LVQL+GV  +++PI I+TE+M+ G L +FLR R   +F+R V+L+ +C  V +GM YLE  +F+HRDLAARNCLV         VKV+DFGMAR++LD+ Y  S+G KFPV+W PPEVF  S ++ K+DVWSFGVLMWEVFT     P+    N +V   +  G RL +P +  + +Y +ML CWQ  P+ RP+FE + + I + ++  CE
Sbjct:  178 DNSEEIVVAMYDFQAAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNYVTGKKSNNLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDS-SQPGLYTVSLYTKFG-GEGSSGFRHYHIKETTT------SPK-KYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELTF-MRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQG-HFSRDVLLS-MCQDVCEGMEYLERNSFIHRDLAARNCLVSEAG----VVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFT-EGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVE--CE 626          

Query:  100 MCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDED-LDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQ----------EASPPGPVDRR 555
            + KRSQ+K   S   YK + FVLT + L Y+E     +   K  + ++ +K VE V+++D +   +N +    V D      N LYI A S   RD W+  ++   K+     + +YHP  W   G Y CC    + + GC+          +A PP P  ++
Sbjct:   11 LIKRSQQKKKTSPLNYKERLFVLTKSMLTYYE-GRAEKKYRKGFIDVSKIKCVEIVKNDDGVIPCQNKYPFQVVHDA-----NTLYIFAPSPQSRDLWVKKLKEEIKNN-NNIMIKYHPKFWTD-GSYQCCRQTEKLAPGCEKYNLFESSIRKALPPAPETKK 165          

Query:   67 VSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQ---------EAS------------PPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSV------------------AQSMPTANSSMLQP-INASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIE--------------VLSADGGA---------------------PSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCEN 2217
            +++DQELKISRM KRS  K IFSR  YKL+EFVLTP ++KYFE+SGGNRGKEK  +LL+ +K+VEKV D+DLD KKNV Q+AYVED  STN  +LYIVA S  ERDDWI+LIR+Y ++R A FLPRYHPG+W++PGRYSCCDDI+RRS GCQ         EA+            PP       +   +   G++ VA   +      +      G      S  PP +  ++                         N    QP ++  Q  T   + + Q P   + + +EN +K VIAVHNYNPVRENQLPLQKGE+Y+VV+ SN+QWWYV++ AG +GYVPTNYIHKPNSL +FDWYYKD+TRQQAE+ILLEENREGCFLVRDSVSKKNTYTLSVTSKDP+ +GKL+VHHYH H  +              V+S  G                           +YLSEKHAF TIS+VIHYHKHNSGGLV RLRSPP++D ESPVTAGMGLDEFELDPAEL+++  PIGKGQFGVVK+G+FR +PVAVKQMVE AMNE+DFI+EAKNMRFLNHPNLVQLFGVV+KKRPIMIITEYMK+GSLRDFLR R S + NRPVVLADICAQV  GMAYLE E FVHRDLAARNCLVK+VSR SV VKVADFGMARFLLDNVYEPSAGTKFPVRWA PEVFQS+YT KADVWSFGVLMWEVFT C ENPYHG NNSQVYQ+I+GGGRL KP +CPDR+YVLMLECWQHD  KRPAFEY+CQKIGDYLDQNCEN
Sbjct:    1 MATDQELKISRMTKRSVNKKIFSRPSYKLREFVLTPFHIKYFEVSGGNRGKEKGRVLLSNVKYVEKVLDDDLDGKKNVLQVAYVEDSSSTNWFLLYIVAPSLIERDDWISLIRFYTRERGACFLPRYHPGVWRRPGRYSCCDDINRRSHGCQHTFDSSTNTEAAEPHRLSSYPGCPPPVTSTEIQTPPVSPLGGQQSVAVMSSPPQQPQQPAPQQTGKLIIATSPAPPPNPMNIFTQQQVLFQQQQQQQQLLLAQQQKLNVIATQPHLHQHQLSTRRPIRLPQSPGGQSFDWEEN-EKTVIAVHNYNPVRENQLPLQKGEKYYVVNDSNAQWWYVRNVAGQSGYVPTNYIHKPNSLNSFDWYYKDITRQQAEAILLEENREGCFLVRDSVSKKNTYTLSVTSKDPDVSGKLRVHHYHIHRNDGGTNLSNGHSNGAGVVSNGGNTNGNVSATQVNGGTTGSAGGGGGEAQFYLSEKHAFPTISEVIHYHKHNSGGLVVRLRSPPVKDRESPVTAGMGLDEFELDPAELQIDRDPIGKGQFGVVKRGKFRNIPVAVKQMVENAMNEEDFIEEAKNMRFLNHPNLVQLFGVVLKKRPIMIITEYMKYGSLRDFLRQRQSQFCNRPVVLADICAQVGNGMAYLEREQFVHRDLAARNCLVKSVSRNSVVVKVADFGMARFLLDNVYEPSAGTKFPVRWAAPEVFQSVYTDKADVWSFGVLMWEVFTYCMENPYHGMNNSQVYQFIVGGGRLHKPAICPDRIYVLMLECWQHDRNKRPAFEYICQKIGDYLDQNCEN 791          

Query:  412 AKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQ---------EAS------------PPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSV------------------AQSMPTANSSMLQP-INASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIE--------------VLSADGGA---------------------PSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCEN 2217
             ++R A FLPRYHPG+W++PGRYSCCDDI+RRS GCQ         EA+            PP       +   +   G++ VA   +      +      G      S  PP +  ++                         N    QP ++  Q  T   + + Q P   + + +EN +K VIAVHNYNPVRENQLPLQKGE+Y+VV+ SN+QWWYV++ AG +GYVPTNYIHKPNSL +FDWYYKD+TRQQAE+ILLEENREGCFLVRDSVSKKNTYTLSVTSKDP+ +GKL+VHHYH H  +              V+S  G                           +YLSEKHAF TIS+VIHYHKHNSGGLV RLRSPP++D ESPVTAGMGLDEFELDPAEL+++  PIGKGQFGVVK+G+FR +PVAVKQMVE AMNE+DFI+EAKNMRFLNHPNLVQLFGVV+KKRPIMIITEYMK+GSLRDFLR R S + NRPVVLADICAQV  GMAYLE E FVHRDLAARNCLVK+VSR SV VKVADFGMARFLLDNVYEPSAGTKFPVRWA PEVFQS+YT KADVWSFGVLMWEVFT C ENPYHG NNSQVYQ+I+GGGRL KP +CPDR+YVLMLECWQHD  KRPAFEY+CQKIGDYLDQNCEN
Sbjct:   14 TRERGACFLPRYHPGVWRRPGRYSCCDDINRRSHGCQHTFDSSTNTEAAEPHRLSSYPGCPPPVTSTEIQTPPVSPLGGQQSVAVMSSPPQQPQQPAPQQTGKLIIATSPAPPPNPMNIFTQQQVLFQQQQQQQQLLLAQQQKLNVIATQPHLHQHQLSTRRPIRLPQSPGGQSFDWEEN-EKTVIAVHNYNPVRENQLPLQKGEKYYVVNDSNAQWWYVRNVAGQSGYVPTNYIHKPNSLNSFDWYYKDITRQQAEAILLEENREGCFLVRDSVSKKNTYTLSVTSKDPDVSGKLRVHHYHIHRNDGGTNLSNGHSNGAGVVSNGGNTNGNVSATQVNGGTTGSAGGGGGEAQFYLSEKHAFPTISEVIHYHKHNSGGLVVRLRSPPVKDRESPVTAGMGLDEFELDPAELQIDRDPIGKGQFGVVKRGKFRNIPVAVKQMVENAMNEEDFIEEAKNMRFLNHPNLVQLFGVVLKKRPIMIITEYMKYGSLRDFLRQRQSQFCNRPVVLADICAQVGNGMAYLEREQFVHRDLAARNCLVKSVSRNSVVVKVADFGMARFLLDNVYEPSAGTKFPVRWAAPEVFQSVYTDKADVWSFGVLMWEVFTYCMENPYHGMNNSQVYQFIVGGGRLHKPAICPDRIYVLMLECWQHDRNKRPAFEYICQKIGDYLDQNCEN 689          

Query:  742 QPINASQRKTHTN-----VNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGG-------------------------APSY------MYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCEN 2217
            QP NA +R  H       V  +Q+    +++  EN+   VIAVHNYNPVRENQLPLQKGE+Y+VV+ SN+QWWYV++ AG  GYVPTNY+HKPNSL +FDWYYKD+TRQQAE+ILL+ENREGCFLVRDSVSKKNTYTLSVTSKDPE  GKLKVHHYH H  E  SA  G                          PS        YYLSEKHAF TISDVIHYHKHNSGGLV RLRSPP +D ESPVTAGMGLDEFELDPAEL+L   PIGKGQFGVVK+G+FR +PVAVKQMVEGAMNEDDFI+EAKNMRFLNHPNLVQLFGVV+KKRPIMIITEYMKHGSLRDF+R R   +FNRPVVLADICAQVA GMAYLE E FVHRDLAARNCLVK+VSR SV VKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQS YT KADVWSFGVLMWEVFTCC ENPY G +N+QVYQYI+GGGRL KP VCP+R+YVLMLECWQH+P +RP+FEY+CQKIG YLDQNCEN
Sbjct:  343 QPANAIRRSGHNQNRLHPVRYTQQ-TLFDMDDSENT---VIAVHNYNPVRENQLPLQKGEKYYVVNQSNAQWWYVRNMAGQLGYVPTNYVHKPNSLNSFDWYYKDITRQQAEAILLDENREGCFLVRDSVSKKNTYTLSVTSKDPEAPGKLKVHHYHIHRTESASATNGHVNGTGLINGTSATSNGTGGVSRSVGPSTASSTEAQYYLSEKHAFPTISDVIHYHKHNSGGLVVRLRSPPTKDRESPVTAGMGLDEFELDPAELQLEREPIGKGQFGVVKRGKFRNIPVAVKQMVEGAMNEDDFIEEAKNMRFLNHPNLVQLFGVVLKKRPIMIITEYMKHGSLRDFMRQRQPHFFNRPVVLADICAQVANGMAYLEQEQFVHRDLAARNCLVKSVSRNSVHVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSTYTAKADVWSFGVLMWEVFTCCAENPYQGMSNTQVYQYIVGGGRLQKPAVCPERIYVLMLECWQHEPNRRPSFEYICQKIGGYLDQNCEN 866          

Query:   64 MVSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGP 543
            M+S+DQELK+SRM KRSQ K +F RD Y+L+EFVL    ++YFE+SGGNRGKEK  LLL+ +KF+EKVQD+D+D+KKNVFQIAY ED LST+  +LYIVANSA ERDDWI+L+R+Y ++R A FLPRYHPG+WK+PGRYSCCDDI+RRSMGCQ  + PGP
Sbjct:    1 MLSADQELKVSRMTKRSQNKKLFGRDNYRLREFVLHTYCIRYFEVSGGNRGKEKGQLLLSHVKFIEKVQDDDMDSKKNVFQIAYAEDALSTSWYLLYIVANSAIERDDWISLVRFYTRERGAVFLPRYHPGVWKRPGRYSCCDDINRRSMGCQPTNEPGP 160          

Query:  697 TSVAQSMPTANSSMLQ----------PINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSAD-------------GGAPS-------------------YMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCEN 2217
            T     +PT  S M Q          P ++   + H +   +     +  +  EN+   VIAVHNYNPVRENQLPLQKGE+YFVV+ SN+QWWYV++ AG AGYVPTNYIHKPNSL +FDWYYKD+TRQQAE+ILLEE+REGCFLVRDSVSKKNT+TLSVTSKDPE+ GKLKVHHYH H  E  S               GG P+                     +YLSEKHAF TISDVIHYHKHNSGGLV RLRSPP++D ESPVTAGMGLDEFELDPAEL+++  PIGKGQFGVVK+G+FR +PVAVKQMVEGAMNEDDFI+EAKNMRFLNHPNLVQLFGVV+KKRPIMIITEYM++GSLRDFLR R S + NRPV+LADICAQV  GMAYLE E FVHRDLAARNCLVK+VSR S+ VKVADFGMARFLLDNVYEPSAGTKFPVRWA PEVFQSIYT KADVWSFGVLMWEVFT C ENPYHG NN+QVYQ+I+GGGRL KP +CPDRLYVLMLECWQHD  KRPAFEY+CQKIGDYLDQNCEN
Sbjct:  322 TMFPAQLPTTASHMQQCVGPSVTAATPRDSGGARRHGSARFNNPLQPLEFDDSENT---VIAVHNYNPVRENQLPLQKGEKYFVVNQSNAQWWYVRNMAGQAGYVPTNYIHKPNSLNSFDWYYKDITRQQAEAILLEESREGCFLVRDSVSKKNTFTLSVTSKDPEDPGKLKVHHYHIHRTEGSSLSLPNGHSNGFTNGIGGGPANGNSTSNSAGGGGGGAGGEAQFYLSEKHAFPTISDVIHYHKHNSGGLVVRLRSPPVKDRESPVTAGMGLDEFELDPAELQIDRDPIGKGQFGVVKRGKFRNIPVAVKQMVEGAMNEDDFIEEAKNMRFLNHPNLVQLFGVVLKKRPIMIITEYMRYGSLRDFLRQRQSQFCNRPVMLADICAQVGNGMAYLEREQFVHRDLAARNCLVKSVSRNSIVVKVADFGMARFLLDNVYEPSAGTKFPVRWAAPEVFQSIYTDKADVWSFGVLMWEVFTYCLENPYHGMNNAQVYQFIVGGGRLHKPAICPDRLYVLMLECWQHDRNKRPAFEYICQKIGDYLDQNCEN 867          

Query:   67 VSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEAS 531
            +++DQELKISRM KRS  K +FSR  YKL+EFVLTP ++KYF++SGGNRGKEK  + L+ +K+VEKVQDE+LD  KNV Q+ +VED  +    ++Y++A+S+ ERDDWI+LIR+Y+ +R A FLPRYHPG+W++PGRYSCCDDI+RRS+GCQ  +
Sbjct:    1 MATDQELKISRMTKRSSNKKLFSRATYKLREFVLTPCFIKYFDVSGGNRGKEKGRISLSNVKYVEKVQDEELDGNKNVLQLGFVEDAAADAWFLMYVIASSSMERDDWISLIRFYSGERGANFLPRYHPGVWRRPGRYSCCDDINRRSLGCQATT 155          

Query:  697 TSVAQSMPTANSSMLQ----------PINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSAD-------------GGAPS-------------------YMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCEN 2217
            T     +PT  S M Q          P ++   + H +   +     +  +  EN+   VIAVHNYNPVRENQLPLQKGE+YFVV+ SN+QWWYV++ AG AGYVPTNYIHKPNSL +FDWYYKD+TRQQAE+ILLEE+REGCFLVRDSVSKKNT+TLSVTSKDPE+ GKLKVHHYH H  E  S               GG P+                     +YLSEKHAF TISDVIHYHKHNSGGLV RLRSPP++D ESPVTAGMGLDEFELDPAEL+++  PIGKGQFGVVK+G+FR +PVAVKQMVEGAMNEDDFI+EAKNMRFLNHPNLVQLFGVV+KKRPIMIITEYM++GSLRDFLR R S + NRPV+LADICAQV  GMAYLE E FVHRDLAARNCLVK+VSR S+ VKVADFGMARFLLDNVYEPSAGTKFPVRWA PEVFQSIYT KADVWSFGVLMWEVFT C ENPYHG NN+QVYQ+I+GGGRL KP +CPDRLYVLMLECWQHD  KRPAFEY+CQKIGDYLDQNCEN
Sbjct:  228 TMFPAQLPTTASHMQQCVGPSVTAATPRDSGGARRHGSARFNNPLQPLEFDDSENT---VIAVHNYNPVRENQLPLQKGEKYFVVNQSNAQWWYVRNMAGQAGYVPTNYIHKPNSLNSFDWYYKDITRQQAEAILLEESREGCFLVRDSVSKKNTFTLSVTSKDPEDPGKLKVHHYHIHRTEGSSLSLPNGHSNGFTNGIGGGPANGNSTSNSAGGGGGGAGGEAQFYLSEKHAFPTISDVIHYHKHNSGGLVVRLRSPPVKDRESPVTAGMGLDEFELDPAELQIDRDPIGKGQFGVVKRGKFRNIPVAVKQMVEGAMNEDDFIEEAKNMRFLNHPNLVQLFGVVLKKRPIMIITEYMRYGSLRDFLRQRQSQFCNRPVMLADICAQVGNGMAYLEREQFVHRDLAARNCLVKSVSRNSIVVKVADFGMARFLLDNVYEPSAGTKFPVRWAAPEVFQSIYTDKADVWSFGVLMWEVFTYCLENPYHGMNNAQVYQFIVGGGRLHKPAICPDRLYVLMLECWQHDRNKRPAFEYICQKIGDYLDQNCEN 773          

Query:  349 LYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEAS 531
            +Y++A+S+ ERDDWI+LIR+Y+ +R A FLPRYHPG+W++PGRYSCCDDI+RRS+GCQ  +
Sbjct:    1 MYVIASSSMERDDWISLIRFYSGERGANFLPRYHPGVWRRPGRYSCCDDINRRSLGCQATT 61          

Query:  100 MCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLD---NKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPM-RDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSI-YTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQN 2208
            + KRSQ+K   S   YK + FVLT + L Y+E     + K K ++ L  +K VE V++  +      K  FQ+ Y       + N LYI A S   R  W+  ++   ++  +  + ++HP  W++ G + CC    + + GC+E                                           N   +IS  P                  L PI   + K+               +  E  ++ VIA++++       L L +GE Y +++  +  W   ++  G+ GY+P+NY+   +P++L  F WY K++ R +AE  L  E +EG F+VRDS S    YT+S+ +K   + G   + HYH      +    G+P   +YL+EKH F +I +VI YHKHN+ GLV RLR P   ++  +P TAG   +++E++P+EL      +G GQ+GVV+ G++R +  VA+K + EGAM+E+DFI+EAK M  L+HP LVQL+GV  ++RPI ++TE+M+ G L +++R R   +   P  L  IC  +++GM YLE ++++HRDLAARNCLV      S  VKV+DFGMAR++ D+ Y  S+G KFPV+W+PPEVF    Y+ K+DVWSFGVLMWEVFT   + P+    N +V   +  G RL +P +   ++Y +M  CWQ  P++RP+F  +   I D L+ +
Sbjct:   11 LIKRSQQKKRTSPLNYKERVFVLTQSRLTYYEGRPEKKFK-KGSIDLQRVKCVEIVKNGGMVIPCQNKYPFQVVY-------DTNTLYIFAPSNESRSVWVQNMKEEIRNN-SLIVAKFHPQFWQEGG-WLCCGQAEKLAPGCEEY------------------------------------------NLFGDISRKP------------------LPPIPGDESKSRRPPPPPPPVPEPAAQEAELQEEVVIALYDFEGTESQDLTLHRGEEYVIIEKCDVNWHKARNKYGEEGYIPSNYVTLKQPDNLEQFVWYCKNVNRNKAEDQLRNEGKEGGFMVRDS-SSPGAYTVSLYTK---SLGDGAIRHYH------IKETSGSPK-QFYLAEKHLFSSIPEVIDYHKHNAAGLVSRLRYPVNNQNKAAPTTAGFSYEKWEINPSELTFMKE-LGSGQYGVVRLGKWRAQHKVAIKAIREGAMSEEDFIEEAKVMMSLSHPKLVQLYGVCTQQRPIYLVTEFMELGCLLNYIRQRRGSF--SPQNLLSICHDISQGMQYLEEQHYIHRDLAARNCLVND----SHVVKVSDFGMARYVKDDQYVSSSGAKFPVKWSPPEVFNFCKYSSKSDVWSFGVLMWEVFT-EGKMPFEKNLNHEVVAMVTQGHRLYRPKMATPQIYDIMQLCWQERPEERPSFTQISLMITDELEAD 632          

Query:  100 MCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLD---NKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI--HKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPM-RDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSI-YTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQN 2208
            + KRSQ+K   S   YK + FVLT + L Y+E     + K K ++ L  +K VE V++  +      K  FQ+ Y       + N LYI A S   R  W+  ++   ++  +  + ++HP  W++ G + CC    + + GC+E                                           N   +IS  P                  L PI   + K+               +  E  ++ VIA++++       L L +GE Y +++  +  W   ++  G  GY+P+NY+   +P++L  F                    +EG F+VRDS S    YT+S+ +K   + G   + HYH      +    G+P   +YL+EKH F +I +VI YHKHN+ GLV RLR P   ++  +P TAG   +++E++P+EL      +G GQ+GVV+ G++R +  VA+K + EGAM+E+DFI+EAK M  L+HP LVQL+GV  ++RPI ++TE+M+ G L +++R R   +   P  L  IC  +++GM YLE ++++HRDLAARNCLV      S  VKV+DFGMAR++ D+ Y  S+G KFPV+W+PPEVF    Y+ K+DVWSFGVLMWEVFT   + P+    N +V   +  G RL +P +   ++Y +M  CWQ  P++RP+F  +   I D L+ +
Sbjct:   11 LIKRSQQKKRTSPLNYKERVFVLTQSRLTYYEGRPEKKFK-KGSIDLQRVKCVEIVKNGGMVIPCQNKYPFQVVY-------DTNTLYIFAPSNESRSVWVQNMKEEIRNN-SLIVAKFHPQFWQEGG-WLCCGQAEKLAPGCEEY------------------------------------------NLFGDISRKP------------------LPPIPGDESKSRRPPPPPPPVPEPAAQEAELQEEVVIALYDFEGTESQDLTLHRGEEYVIIEKCDVNWHKARNKYGYEGYIPSNYVTLKQPDNLEQF-------------------GKEGGFMVRDS-SSPGAYTVSLYTK---SLGDGAIRHYH------IKETSGSPK-QFYLAEKHLFSSIPEVIDYHKHNAAGLVSRLRYPVNNQNKAAPTTAGFSYEKWEINPSELTFMKE-LGSGQYGVVRLGKWRAQHKVAIKAIREGAMSEEDFIEEAKVMMSLSHPKLVQLYGVCTQQRPIYLVTEFMELGCLLNYIRQRRGSF--SPQNLLSICHDISQGMQYLEEQHYIHRDLAARNCLVND----SHVVKVSDFGMARYVKDDQYVSSSGAKFPVKWSPPEVFNFCKYSSKSDVWSFGVLMWEVFT-EGKMPFEKNLNHEVVAMVTQGHRLYRPKMATPQIYDIMQLCWQERPEERPSFTQISLMITDELEAD 613          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKP-NSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDP-ENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRS-PPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNR--PVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEV-FQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLD 2202
            VIA + Y P+    L L+K E Y V+   ++ W   +   G  GY+P+NY+ +  N L   +WY K++ R QAE++L  EN++G FLVRDS      YT+SV +K   E +G  +       H  +L+   G     +YL+EKH F  I D+I+YH+HN+ GLV RL+     R   +P TAG+G   +E+DP +L      +G GQFGVVK G+++ R  VA+K + EG+M+EDDFI+EAK M  L H NLVQL+GV  K+RPI I+TE++ +G L  +LR    DY     P++L ++C  V +GMAYLE + ++HRDLAARNCLV +    +  VKV DFG++R++LD+ Y  S G+KFPVRW+PPEV   S ++ K+D+W+FGVLMWE++T     PY   NN+++ + + GG RL +P +  DR+Y +M  CW     +RP F+ +   I D ++
Sbjct:  141 VIAEYEYAPMAPQDLELRKDEEYTVLQICDANWLRARDKYGQEGYIPSNYVVEALNGLEKCEWYCKNMNRSQAENLLKTENKDGGFLVRDSGRLAGKYTVSVFTKSGGETSGSSR-------HYNILTTQQGQ----FYLAEKHYFNNIPDLINYHQHNAAGLVSRLKYIVSNRAQHAPSTAGLGYGVWEIDPRQLTF-IKELGNGQFGVVKYGKWQGRHDVAIKMIKEGSMSEDDFIEEAKVMMKLRHENLVQLYGVCTKQRPIYIVTEFLPNGCLLTYLR----DYLQHPSPLLLLEMCKDVTEGMAYLESQQYIHRDLAARNCLVDS----NGTVKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLLYSKFSSKSDIWAFGVLMWEIYT-LGRMPYDRMNNTEIVEKVSGGHRLYRPQLANDRIYSVMTSCWHDKADERPTFQDLVMIIQDLVE 579          

Query:  844 VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKP-NSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDP-ENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRS-PPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNR--PVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEV-FQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLD 2202
            VIA + Y P+    L L+K E Y V+   ++ W   +   G  GY+P+NY+ +  N L   +WY K++ R QAE++L  EN++G FLVRDS      YT+SV +K   E +G  +       H  +L+   G     +YL+EKH F  I D+I+YH+HN+ GLV RL+     R   +P TAG+G   +E+DP +L      +G GQFGVVK G+++ R  VA+K + EG+M+EDDFI+EAK M  L H NLVQL+GV  K+RPI I+TE++ +G L  +LR    DY     P++L ++C  V +GMAYLE + ++HRDLAARNCLV +    +  VKV DFG++R++LD+ Y  S G+KFPVRW+PPEV   S ++ K+D+W+FGVLMWE++T     PY   NN+++ + + GG RL +P +  DR+Y +M  CW     +RP F+ +   I D ++
Sbjct:  160 VIAEYEYAPMAPQDLELRKDEEYTVLQICDANWLRARDKYGQEGYIPSNYVVEALNGLEKCEWYCKNMNRSQAENLLKTENKDGGFLVRDSGRLAGKYTVSVFTKSGGETSGSSR-------HYNILTTQQG----QFYLAEKHYFNNIPDLINYHQHNAAGLVSRLKYIVSNRAQHAPSTAGLGYGVWEIDPRQLTF-IKELGNGQFGVVKYGKWQGRHDVAIKMIKEGSMSEDDFIEEAKVMMKLRHENLVQLYGVCTKQRPIYIVTEFLPNGCLLTYLR----DYLQHPSPLLLLEMCKDVTEGMAYLESQQYIHRDLAARNCLVDS----NGTVKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLLYSKFSSKSDIWAFGVLMWEIYT-LGRMPYDRMNNTEIVEKVSGGHRLYRPQLANDRIYSVMTSCWHDKADERPTFQDLVMIIQDLVE 598          

Query:   67 VSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDED--LDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVD-RRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYI----------------------------HKPNSLTT----------FDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDY 2196
            +S +  +K   + K SQ+K   S   YK + F+LT   L Y+E   G R  +K  +    +  VE V+ ED     ++  FQIAY       +  ILY+ A   A+R DWI+++    KD  +    +YH G W   G++SCC        G    + PG +   ++S++   +   R  A++L+++              H      PP   + V+ ++                                          ++A+++Y+     +L L KG  Y  ++ S+  WW V+   G  G++P NY                             H   SL++          + WY  +++R + E +L E+ + G F+VRDS SK+ +YT+S+ ++  +      V HY  +    ++A+G      YYL+E H F TI  +I YH+HNS G+  RLR P     ++P +A     E+EL   +++L    +G GQFGVV+ G ++ +  VA+K + EG M+ DDFIDEA+ M  L HP LV+L GV  ++ PI I+TE+M +G L DFLR+   +   +P  L ++C  V + MAYLE + F+HRDLAARNCLV     + + VKV+DFGMAR++LD+ Y  S GTKFPV+W+ PEV   + ++ K+DVW+FGVLMWEV++   + PY   +N QV + ++ G RL +P +  D++Y +M  CW   P++RP F+ +   +  +
Sbjct:    1 MSEEGVVKEGILLKMSQQKKKISPKNYKERLFILTNKTLSYYEHEKGKRKAKKGVVAAEKICCVEIVEPEDNAPAQREFPFQIAY-------DDCILYLFAKDDADRRDWIDVLMNVIKDN-SKLSIKYHKGFWMD-GKFSCC--------GQTVKNAPGCIQWHKDSADGLISSVRRFGASSLSSK--------------HRESVHLPPIPESEVSSALE-----------------------------------------IMALYDYSAQSPEELSLVKGSVYVCLEKSSDDWWKVRDTDGFEGFIPANYTKELEIKDYSIKTEIPRRSLKERPSGTKSHSAESLSSISPEKDSIEDYPWYVGNMSRAKTEQMLREKGKVGSFVVRDS-SKRGSYTVSLLNQATDEVTG-TVSHYLIN----VNAEGK-----YYLAENHLFDTIPRMIEYHQHNSAGMSTRLRRPATESDDTPPSAH---GEWELCREDVEL-VKELGSGQFGVVQLGMWKGQHEVAIKMVKEGCMSSDDFIDEAQIMMKLRHPKLVRLHGVCTERFPIYIVTEFMSNGCLLDFLRSHGKEM--QPPQLLNMCLDVCEAMAYLEDQQFIHRDLAARNCLVD----KDLTVKVSDFGMARYVLDDQYTSSPGTKFPVKWSAPEVLNYTKFSSKSDVWAFGVLMWEVYS-LGKQPYEHYDNGQVAEKVMQGHRLYRPQLATDQIYQVMKACWHEAPEERPNFQLLLNDLSTF 659          

Query:  841 WVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPN--SLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPM---RDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMP--VAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVF-QSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKI 2187
            WV A++N        L L  G+ Y V+D S+  WW  +   G  G++P+NY+ +     L  ++WY KD++R  AE +L EE +EG F+VRDS S    YT+S+ +    + G +K  HY    +         P  MYY++E H F+ I ++I+YH+HNS GLV RL+   +   R             ++E+DP+EL L    +G GQFGVV+ G ++R+   VA+K + E  M+EDDFI+EAK M  L HP LV  +GV  +KRP +++TEYM+ G+L  F+R R     N    L  +CA V + MAYLE E+F+HRDLAARNCLV         VKV+DFGM+R++LD+ Y  S+GTKFPVRW+PPEVF  + ++ K+DVW+FG+LMWEVF+     PY   +NS V + +  G RL +P      ++++M  CW   P++RP+F+ + + I
Sbjct:  121 WVEALYNLTVTESQDLSLVAGQEYRVLDHSDEYWWKARDKQGREGFIPSNYVMEKTFKGLEAYEWYSKDISRSMAEQLLKEEGKEGGFVVRDS-SHAGVYTVSIYTNSLGDTGVVK--HYQIKEV-------CEPQRMYYVAENHLFENIPNLINYHQHNSAGLVARLKHSVLSRARTASFSSGQSSESRQWEIDPSELSL-LQELGSGQFGVVRLGVWKRVRGNVAIKMLHEATMSEDDFIEEAKTMMRLWHPKLVHFYGVSCRKRPFLLVTEYMEAGNLESFVRERRGA--NSASQLLQMCADVCEAMAYLERESFLHRDLAARNCLVNAQG----TVKVSDFGMSRYVLDDQYTSSSGTKFPVRWSPPEVFLNNKFSSKSDVWAFGILMWEVFSEGM-LPYDPWSNSNVVEQVQAGYRLYRPERATQPVHLIMHSCWHERPEERPSFQSLLESI 559          

Query: 1027 WYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHES---PVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMP-VAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMA--RFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAF 2166
            +Y KD+TR +AE +L ++ ++G ++VRDS S+   +T+SV +  P       + HYH       ++ G      ++L+EKH F +I ++I YH+HN+  LV RLR P   +H+S   P T G    ++E+DP EL      +G GQ+GVV+ G+++R   VAVK + EGAM+E+DFI+EAK M  L+HP LVQL+GV  ++RP+ I+TEYM  GSL  FL+++       P ++A+IC  V + M+YLE + F+HRDLAARNCLV   +     VKV+DFGM   R++LD+ Y  S G KFPV+W+PPEVFQ + ++ K+DVWSFGVLMWEV+T     P+ G +N QV   I+ G RL +P + P   Y +ML+CWQ  P+ R +F
Sbjct:    1 YYSKDVTRVRAEQLLKQQGKDGSYMVRDS-SQSGKFTVSVFTTKPTET----IKHYHIKE----TSHG-----QFFLAEKHVFSSIPELIIYHQHNAAVLVVRLRHPV--NHQSIGAPTTVGFSYQKWEIDPQELTFTH-ELGSGQYGVVRLGQWKRQKLVAVKMIQEGAMSEEDFIEEAKVMMQLSHPRLVQLYGVCTQQRPLCIVTEYMVGGSLLSFLKSQRGS--TVPELMAEICLDVCEAMSYLEEKMFLHRDLAARNCLVGEGNI----VKVSDFGMTSHRYVLDDQYTCSMGAKFPVKWSPPEVFQYTRFSTKSDVWSFGVLMWEVYT-EGHMPFEGWSNQQVVDEILRGCRLYQPALSPPTAYNIMLDCWQEKPESRCSF 363          

Query:  778 NVNVSQKPAAINIEGDENSDKWV-----IAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDA-GYVPTNYIHKPNSLTTFDWYYKDLTRQQAE-SILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSP-----PMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEF-RRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDY 2196
             V+  + P    +EG    +++V     +A+++Y+P+  + L  ++G++  +V+  N  WW  +S A    GY+P+N++ K NS+   +W++K L+R+ AE  +LL  N+ G +L+RDS + K +Y+LSV     E    +K       H ++ + D G     Y+++ +  F T+ +++ Y+   + GL ++L  P     P +  E         D +E+    +KL    +G GQFG V  G + ++  VAVK M  G+M    F++EA  M+ L H  LV+L  VV  + PI I+TEYM+ GSL DFL+        +P ++ D+CAQVA+GMA++E +N++HRDL A N LV      ++  K+ADFG+AR + DN Y    G KFP++W  PE      ++ K+DVWSFG+L+ E+ T     PY G  N +V + +  G R+ KP  CP  LY +M ECW+  P++RP FEY+   + D+
Sbjct:   41 GVSEIRTPTITTLEGSGFPNRYVDGLLVVALYDYDPIHADDLCFRRGDQLVIVEEGND-WWKARSVATKKEGYIPSNFVAKVNSIEKEEWFFKGLSRKDAERQLLLCGNKIGSYLIRDSETNKGSYSLSVRDHIVEVGDTVK-------HYKIRTLDKGG----YFITSRITFHTLQELVVYYHLKADGLCQKLGKPCIAIQPQKPWEK--------DAWEIPRESIKLEKK-LGAGQFGDVWMGVYNKKTKVAVKMMKPGSMAPQAFLEEANLMKTLQHDKLVRLHAVVTDE-PIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMI-DMCAQVAEGMAFIEDKNYIHRDLRAANILVNV----NLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVT-FGRIPYPGMTNPEVIRSLERGYRMPKPDNCPCELYSIMQECWRQKPEERPTFEYLQSLLEDF 499          

Query:  847 IAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDA--------GYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEE-NREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMG---LDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMP-VAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFL---LDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCEN 2217
            +A+++Y+      L  ++GE   V D +NS WWY +              GY+P NY+ +  SL    W++ D+ R  AE  LL + N  G FL+R S S+K  Y+LSV            V HY    I  L  +GG     +++S +  FQ + +++ Y+K NS GL   L+ P +   E+P T G+    +D++E+  A ++L    +G G FG V +G +     VAVK +  GAM +++FI EA+ M+ L H NL+QL+ V  ++ PI IITE M+HGSL D+LR         P  L D+  Q+A GMAYLE +N++HRDLAARN LV          KVADFG+AR +    ++ YE  AG K P++W  PE      ++ K+DVWSFG+L++E+ T     PY    N +V + +  G R+ +P  CP   Y +MLECW    ++RP FE +  ++ DY D +  N
Sbjct:    2 VALYDYDGRTNEDLSFKEGELLEVTDKTNSDWWYAQKKTASTSNERYNTRGYIPANYVAEYQSLDAEPWFFGDIKRADAEKYLLADVNTTGAFLIRQSESRKTDYSLSVRDGS-------TVKHYR---IRQLDENGG-----FFISRRVTFQNLIELVQYYKSNSDGLCMALQKPCVV-IEAPTTIGLSYNTVDKWEIPRASIQLQKR-LGAGMFGEVWQGLWNNSTLVAVKTLKPGAMKKEEFIGEAQIMKQLRHANLIQLYAVCSQEEPIYIITELMRHGSLLDYLRGPLGKQLKAP-ELVDMARQIAAGMAYLESQNYIHRDLAARNILVG----EGKVCKVADFGLARIIKVRYEDEYEGKAGAKVPIKWTAPEAVNFHRFSVKSDVWSFGILLYELIT-YGRMPYPEMGNMEVLKQLDRGYRMPQPDNCPPLFYSIMLECWNKKEEERPTFETLQWRL-DYFDSDPNN 451          

Query:  847 IAVHNYNPVRENQLPLQKGERYFVVDSS--------NSQWWYVKS-AAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAE-SILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYL 2199
            +A+++Y+   ++ L  +KGE++ +++++           WW  +S + G+ GY+P+NY+   +S+   +WY+  ++R+ AE  +L   N  G FL+R+S + K  Y+LS+  +D +      V HY    ++    +GG     YY++ +  F T+  ++ ++  ++ GL  +L    +  +E P T G+  D +E+    LKL    +G+G FG V  G +     VA+K +  G M+ + F++EA+ M+ L H  LVQL+ VV  + PI I+TE+M  GSL DFL+     Y   P  L D+ AQ+A GMAY+E  N++HRDL A N LV      ++  K+ADFG+AR + DN Y    G KFP++W  PE      +T K+DVWSFG+L+ E+ T     PY G  N +V + +  G R+  P  CP+ L+ LM++CW+ DP++RP FEY+   + DY 
Sbjct:   19 VALYDYDARTQDDLSFRKGEKFQIINNTIEVAVVYREGDWWEARSLSTGNKGYIPSNYVAPADSVQAEEWYFGKVSRKDAERQLLCPGNPRGTFLIRESETTKGAYSLSI--RDWDEVKGDNVKHYKIRKLD----NGG-----YYITTRAQFDTLQKLVQHYSEHADGLCYKLTL--VCPNEKPQTQGLARDAWEMPRDSLKLE-LKLGQGCFGEVWAGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVV-SEEPIYIVTEFMSKGSLLDFLKEGDGRYLKLPQ-LVDMAAQIAAGMAYIERMNYIHRDLRAANILVGD----NLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAAMFGRFTIKSDVWSFGILLTELVTK-GRVPYPGMVNREVLEQVERGYRMPCPPSCPESLHELMMQCWKKDPEERPTFEYLQAFLEDYF 460          

Query: 1369 PVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKG-EFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNH----PNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVY--EPSAGTKFPVRWAPPEVFQS--IYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLE-----CWQHDPKKR 2157
            P  +  GL E E+D + L   +  IG+G+FGVV KG   +   V   +++    + D+  D  + ++FL       N+ + +G  +K   + II E+   GSLR  LR    D     V++ ++       +  +  +N +HRD+ A N L+         VK+ DFG+A  +       +  AGT +   W  PEV      Y  K D+WS G+  +E+ T     PY      +  Q II     +KP    DR Y   L+     C   DPK+R
Sbjct:    5 PQNSKQGLAEGEMDVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLV----ALKCIHKDNVIHRDIKAANVLITNEG----NVKLCDFGVAAQVNQTSLRRQTMAGTPY---WMAPEVIMEGVYYDTKVDIWSLGITTYEIATG--NPPYCDVEALRAMQLIIK----SKPPRLEDRSYSTSLKEFIALCLDEDPKER 264          

Query: 1441 IGKGQFG------VVKKGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVL 2121
            +G G FG       V  G +  + V  KQ V      +   DE + ++ + HP L++++G     R I ++ +Y++ G L   LR   S  F  PV      A+V   + YL   N ++RDL   N L+     R+  +K+ DFG A+  +  V     GT  P   AP  +    Y    D WS GVL++E+    T  P++     + Y+ I+ G  +  P   PD + +L
Sbjct:   76 LGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRK--SQRFPNPVA-KFYAAEVILALEYLHAHNIIYRDLKPENILLD----RNGHIKITDFGFAK-EVQTVTWTLCGT--PDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYT--PFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLL 296          

Query: 1441 IGKGQFGVVKKG--EFRRMPVAVKQMV-EGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSI-YTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKI 2187
            IG+G +GVV K   +     VA+K++V E     +D + E   ++ LNH N+V+  G + K   + I+ EY  +GSLR  +   S+              Q   G+ YL  E  +HRD+ A N L+   +     VK+ADFG++  ++++     AGT   + W  PE+  +   +  +D+WS G  + E+ T     PYH   ++ +Y Y +       P    + L   + +C+  +  KRP  + + + +
Sbjct:   31 IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENES--KTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADN----TVKLADFGVST-IVNSSALTLAGT---LNWMAPEILGNRGASTLSDIWSLGATVVEMLT--KNPPYHNLTDANIY-YAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHV 270          

Query: 1441 IGKGQFGVVK------KGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPD 2106
            +G G FG V        G F  +    K  +      +   DE + +  ++HP +++++G     + + ++ +Y++ G L   L  R S  F  PV      A+V   + YL  ++ ++RDL   N L+     ++  +K+ DFG A+++ D  Y    GT  P   AP  V    Y    D WSFGVL++E+    T  P++  N  + Y+ I+       P   PD
Sbjct:   94 LGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLL--RKSQRFPNPVA-KFYAAEVCLALEYLHSKDIIYRDLKPENILLD----KNGHIKITDFGFAKYVPDVTYT-LCGT--PDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYT--PFYNSNTMKTYENILNAELKFPPFFHPD 309          

Query: 1441 IGKGQFGVVK------KGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYII 2067
            +G G FG V        G +  M V  K++V      +   DE   +  + HP +++++G     + I +I +Y++ G L   LR   S  F  PV      A+V   + YL  ++ ++RDL   N L+     ++  +K+ DFG A+++ D  Y    GT  P   AP  V    Y    D WSFG+L++E+    T  P++  N  + Y+ I+
Sbjct:   93 LGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRK--SQRFPNPVAKF-YAAEVCLALEYLHSKDIIYRDLKPENILLD----KNGHIKITDFGFAKYVPDVTY-TLCGT--PDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYT--PFYDSNTMKTYEKIL 295          

Query: 1489 MPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEV-FQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECW 2136
            +PVAVK M +GAM+E+DFI+EAK M+   H NLVQL+G+  +K PI II E MK G L  +LR   S +  +   + ++  QVA  M YLE  NF+HRDLAARNCL+      +  VKVADFG+AR+++D+ Y  S GTKFP++WA PEV   S ++ K+DVW+FG+L WEV+T   + PY   NN+ V Q +I G RL KP+ CPD  Y  M +CW
Sbjct:    6 IPVAVKMMKDGAMSEEDFIEEAKVMKQFQHGNLVQLYGICSEK-PIYIIQELMKGGCLLHYLRK--SQFKLQSAEMTEMVRQVAAAMKYLESHNFIHRDLAARNCLIG----ENRTVKVADFGLARYVIDDEYTASEGTKFPIKWAAPEVILYSKFSSKSDVWAFGILAWEVYT-GGKQPYPATNNTDVVQMVINGYRLEKPLRCPDAAYSTMRKCW 214          

Query: 1393 DEFELDPAELKLNSTPIGKGQFGVVKKGEFRRM--PVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVF-QSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKI 2187
            DE+E++  E+ +    +G GQ+G V +G +++    VAVK + E  M  ++F+ EA  M+ + H NLVQL GV  ++ P  IITE+M +G+L D+LR+      +  V L  +  QV   M+YLE  NF+HRDLAARNCLV   +     VKVADFG++R + +++Y    G KFP++W  PE    + ++ K+DVW+FG+L+WE+ T    +PY G + SQVY  + GG R+  P  CP  +Y LM  CW  DP  RP+F+ + +K+
Sbjct:    5 DEWEIERTEIAMKHK-LGGGQYGEVYEGTWKKYNKTVAVKTLREETMEVEEFLKEASVMKGIKHQNLVQLLGVCTREPPFYIITEFMMNGNLLDYLRSPKGKDLDA-VTLMYMATQVGSAMSYLESMNFIHRDLAARNCLVGDNNL----VKVADFGLSRLVSEDIYTAHQGAKFPIKWTAPEALAHNTFSIKSDVWAFGILLWELATYGM-SPYPGIDLSQVYDKLDGGYRMPCPEGCPPEVYSLMQTCWCWDPNSRPSFKEIHEKL 265          

Query: 1402 ELDPAELKLNSTPIGKGQFGVVKKGEFRR-----MPVAVKQMVEGAM--NEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKI 2187
            ELD   LKL    IG G+FG V KG  +R     +PVA+K + +G+   N  DF+ EA  M     PN++ L GVV K  P+MI+TE+M +GSL +FL+   S      + L  +   +A GM YL   NFVHRDLAARN LV      ++  KVADFG++R L D+ YE S G K PVRW  PE  +   ++  +DVWS+G+L+WE F+   E PY   +N +V   +  G RL  P+ CP  ++ +MLECW  D  KRP+F  + +++
Sbjct:   52 ELDKRWLKLEKV-IGGGEFGDVYKGTLKRPGENTIPVAIKTLKQGSTSKNRGDFLSEASVMGQFCDPNVIFLEGVVSKTHPLMIVTEFMSNGSLDNFLKKMDSKL--SLIQLMGMARGIASGMKYLSEMNFVHRDLAARNILVT----ETLVCKVADFGLSRELEDSAYETSGG-KIPVRWTAPEAIKYRKFSTSSDVWSYGILLWETFSFA-ERPYWDWSNFEVMDRVETGYRLPPPMSCPKVIHQIMLECWDADRTKRPSFALIVKQL 312          

Query: 1393 DEFELDPAELKLNSTPIGKGQFGVVKKGEFR-------RMPVAVKQMVEGAMNED--DFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVV-------------LADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKF-PVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQ 2205
            DE+E+   ++KL    +G G FG+V +GE         +  VAVK + E A   D  +F+ EA  M+     ++V+L GVV   +P +++ E M +G L++FLR+      +RP V             +  +  ++A GMAYL    FVHRDLAARNC+V      ++ VK+ DFGM R + +  Y    G    PVRW  PE  +  ++T  +DVWSFGV+MWE+ T  ++ PY GK+N +V +Y++ GG + KP  CPDRL+ LM  CWQ  PK RP F  +   I + L Q
Sbjct:    9 DEWEVPREKIKLIRE-LGNGSFGMVYEGEATDIVPNKPKCKVAVKTVSENASIRDRIEFLQEASIMKAFQCNHVVRLLGVVSDGQPTLVVMELMDNGDLKNFLRS------HRPEVTMESDEPPPTLQQMLQMAGEIADGMAYLAARKFVHRDLAARNCMVNA----NLTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTSPSDVWSFGVVMWEMATLASQ-PYPGKSNEEVLKYVVDGGVMPKPDDCPDRLFDLMTLCWQFSPKARPTFLSIISLIEEDLSQ 291          

Query: 1369 PVTAGMGLDEFELDPAELKLNSTPIGKGQF-----GVVKKGEFRRMPVAVKQMVEGAM--NEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSA-----GTKFPVRWAPPEVFQ-SIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYL 2199
            P+ A M + + E++  +LKL    IG G+F     GV+   +  +  VAVK +  G+   N +DF  EA  M   +HPN++ L GV+ + RP+MIITE++++GSL +FL  +S+D     + L  I   VA GMAYL   NF+HRDLAARN LV      ++  KV+DFG++R L D+     +     G K PVRW  PE  +   ++  +DVWS+G+L+WE+ +   E PY   +N QV   + GG RL  P+ CP  ++ LML+CW  +   RP F  + ++  + +
Sbjct:   11 PMEALMSVAK-EINKDDLKL-EIIIGGGEFADVYRGVLTNEDKTQEKVAVKILKPGSSHKNREDFCVEASIMGQFDHPNVIALKGVITRTRPMMIITEFLENGSLDNFL--KSNDGRLTTLQLVGIGRGVAAGMAYLSEMNFIHRDLAARNILVSD----NLAAKVSDFGLSRELDDSPENEQSEYQTQGGKIPVRWTAPEAIRYRKFSSASDVWSYGILLWEIMSFG-ERPYWTWDNFQVMDRVEGGYRLPAPMKCPKVIHNLMLDCWDKEKTSRPKFADIVRRFDEVI 291          

Query:  106 KRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISG--GNRGKEKCTLLLNFLKFVEKVQDE--DLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWIN----LIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNS-LTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVV--LADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEV-FQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYL 2199
            KRSQ+K   S   YK + FVLT   L Y++     G R   + ++ +  +K VE V+ E      ++  FQ+ Y E         LYI A S   R +WI     L+RY  KD     + +YHP  W   G + CC    +++MGC+     G   R  S                                T   +   P +   S ++ +P       QP +A+   + T                      VIA ++Y P+    L L+  E Y +++ S+  WW  +   G  GY+P+NY+ +  S L  F WY K++ R QAE +L  EN++G FLVRDS SK   YT+S+ +K     G     HY+             P   +YLSEKH F TI ++I+YH+HN+ G+V RL+         P TAG+G   +E+DP  L      +G GQFGVVK G+++ +  VA+K + EG+M+EDDFI+EAK M  L H NLVQL+GV  K+RPI I+TE++ +G L  +L+         P    L ++C  V++GMAYLE + ++HRDLAARNCLV      +  VKV DFG++R++LD+ Y  S G+KFPVRW+PPEV   S ++ K+D+W++GVLMWEV+T     PY   NNS++   +  G RL +P +  +R+Y +M  CW   P +RP F+ +   + D L
Sbjct:   12 KRSQQKKKTSPLNYKERLFVLTAEKLAYYDYDADKGKRKGLRGSVDVEKIKCVETVETEPNAPQERRFAFQVVYDE-------GPLYIFAKSENSRTEWITKLKELVRY-NKD----LMQKYHPCFWAD-GVWLCCQQEVKQAMGCKILDKNGYASRTRS--------------------------------TRKPLPPTPSEEKPSPSRRLPP------QPESAAPSSSMT----------------------VIAEYDYTPMTAQDLELRTNEEYTILEKSDPNWWRARDKYGKEGYIPSNYVAEAESGLERFHWYCKNMNRSQAEQLLKSENKDGGFLVRDS-SKAGKYTVSLFAKSGAETGG-SCRHYNI---------CTTPQGQFYLSEKHNFDTIPELINYHQHNAAGMVCRLKHIVSNRARPPSTAGLGYGVWEIDPHYLTFIKE-LGTGQFGVVKYGKWQGQHDVAIKMIKEGSMSEDDFIEEAKIMMKLRHENLVQLYGVCTKQRPIYIVTEFLANGCLLTYLKE---GLIQHPTADQLLEMCKDVSEGMAYLESQQYIHRDLAARNCLVDA----NGTVKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLLYSKFSSKSDIWAYGVLMWEVYT-LGRLPYERLNNSEIVDQVSHGFRLYRPQLANERVYKIMTSCWHDKPDERPTFQDLVLIVQDLL 629          

Query:  106 KRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISG--GNRGKEKCTLLLNFLKFVEKVQDE--DLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWIN----LIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNS-LTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVV--LADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEV-FQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYL 2199
            KRSQ+K   S   YK + FVLT   L Y++     G R   + ++ +  +K VE V+ E      ++  FQ+ Y E         LYI A S   R +WI     L+RY  KD     + +YHP  W   G + CC    +++MGC+     G   R  S                                T   +   P +   S ++ +P       QP +A+   + T                      VIA ++Y P+    L L+  E Y +++ S+  WW  +   G  GY+P+NY+ +  S L  F WY K++ R QAE +L  EN++G FLVRDS SK   YT+S+ +K     G     HY+             P   +YLSEKH F TI ++I+YH+HN+ G+V RL+         P TAG+G   +E+DP  L      +G GQFGVVK G+++ +  VA+K + EG+M+EDDFI+EAK M  L H NLVQL+GV  K+RPI I+TE++ +G L  +L+         P    L ++C  V++GMAYLE + ++HRDLAARNCLV      +  VKV DFG++R++LD+ Y  S G+KFPVRW+PPEV   S ++ K+D+W++GVLMWEV+T     PY   NNS++   +  G RL +P +  +R+Y +M  CW   P +RP F+ +   + D L
Sbjct:   12 KRSQQKKKTSPLNYKERLFVLTAEKLAYYDYDADKGKRKGLRGSVDVEKIKCVETVETEPNAPQERRFAFQVVYDE-------GPLYIFAKSENSRTEWITKLKELVRY-NKD----LMQKYHPCFWAD-GVWLCCQQEVKQAMGCKILDKNGYASRTRS--------------------------------TRKPLPPTPSEEKPSPSRRLPP------QPESAAPSSSMT----------------------VIAEYDYTPMTAQDLELRTNEEYTILEKSDPNWWRARDKYGKEGYIPSNYVAEAESGLERFHWYCKNMNRSQAEQLLKSENKDGGFLVRDS-SKAGKYTVSLFAKSGAETGG-SCRHYNI---------CTTPQGQFYLSEKHNFDTIPELINYHQHNAAGMVCRLKHIVSNRARPPSTAGLGYGVWEIDPHYLTFIKE-LGTGQFGVVKYGKWQGQHDVAIKMIKEGSMSEDDFIEEAKIMMKLRHENLVQLYGVCTKQRPIYIVTEFLANGCLLTYLKE---GLIQHPTADQLLEMCKDVSEGMAYLESQQYIHRDLAARNCLVDA----NGTVKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLLYSKFSSKSDIWAYGVLMWEVYT-LGRLPYERLNNSEIVDQVSHGFRLYRPQLANERVYKIMTSCWHDKPDERPTFQDLVLIVQDLL 629          

Query:  850 AVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNS--LTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMR-DHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDY--FNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSI-YTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLD 2202
            A++++     + L L KG+ Y +V+ S++ W+  ++  G+ GY+P+NY+ +  S  L  + WY K + R +AE +L  E++ G F+VRDS S   TYT+SV +K P   G   + HYH    E       A    +YL+EKH F +I ++I YHKHN+ GLV RLR P  + D  +P TAG   + +E++P+EL      +G GQFG V+ G++R +  VA+K + EGAM+E+DFI+EAK M  L+HP LVQL+GV  +++PI I+TE+M+HGSL  FL+     +   +   +  D+C    +GM YLE   F+HRDLA+RNCLV      S+ VKV+DFGM RF+LD+ Y  S+G +FPV+W+PPEVF    Y+ K+DVWS+GVLMWEVFT     P+    N +V   ++ G RL KP +    LY +M  CW+  P+ RP+F  +C  + D L+
Sbjct:  194 ALYDFPATEPHDLRLIKGDEYIIVERSDANWFKARNHYGEEGYIPSNYVTEKISGNLVQYGWYSKQVNRNKAEELLRNEDKAGAFMVRDS-STPGTYTVSVYTKAPAGDGGGAIKHYHIKKTE-------ASPPQFYLAEKHLFYSIPELIEYHKHNAAGLVTRLRYPVGKPDKSAPSTAGFSYEMWEINPSELTFMKE-LGCGQFGQVRLGKWRAQHKVAIKFIREGAMSEEDFIEEAKIMMKLSHPKLVQLYGVCSQQKPIYIVTEFMEHGSLLHFLQRGRGGFSLGSLLSISLDVC----EGMEYLEAHGFIHRDLASRNCLVND----SLAVKVSDFGMTRFVLDDQYTSSSGARFPVKWSPPEVFNFCKYSSKSDVWSYGVLMWEVFT-EGRMPFDNNLNHEVVTLVMQGHRLYKPKLATPTLYEIMHLCWKERPEDRPSFSRLCVMLSDTLE 633          

Query:   97 RMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLD---NKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEAS----------PPGPVDRR 555
            R+ KRSQ+K I S   YK + FVLT   L Y++     + K K ++ L+ ++ VE V++         K  FQI Y       + N LY+ A S + R  W+  ++   KD     L ++HP  W   G + CC  + ++++GC+E +          PP PV R+
Sbjct:   10 RLIKRSQQKKITSPLNYKERLFVLTKNKLTYYDGKPEKKFK-KGSIELSRIRCVEIVKNGGGTIPCQNKYPFQIVY-------DTNTLYVFAPSQSSRSIWVQSLKDEIKDN-QVVLVKFHPLFWLD-GAWLCCRQVEKQALGCEEYNLFGDITRKPLPPLPVKRQ 165          

Query:  850 AVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNS--LTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMR-DHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDY--FNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSI-YTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLD 2202
            A++++     + L L KG+ Y +V+ S++ W+  ++  G+ GY+P+NY+ +  S  L  + WY K + R +AE +L  E++ G F+VRDS S   TYT+SV +K P   G   + HYH    E       A    +YL+EKH F +I ++I YHKHN+ GLV RLR P  + D  +P TAG   + +E++P+EL      +G GQFG V+ G++R +  VA+K + EGAM+E+DFI+EAK M  L+HP LVQL+GV  +++PI I+TE+M+HGSL  FL+     +   +   +  D+C    +GM YLE   F+HRDLA+RNCLV      S+ VKV+DFGM RF+LD+ Y  S+G +FPV+W+PPEVF    Y+ K+DVWS+GVLMWEVFT     P+    N +V   ++ G RL KP +    LY +M  CW+  P+ RP+F  +C  + D L+
Sbjct:  194 ALYDFPATEPHDLRLIKGDEYIIVERSDANWFKARNHYGEEGYIPSNYVTEKISGNLVQYGWYSKQVNRNKAEELLRNEDKAGAFMVRDS-STPGTYTVSVYTKAPAGDGGGAIKHYHIKKTE-------ASPPQFYLAEKHLFYSIPELIEYHKHNAAGLVTRLRYPVGKPDKSAPSTAGFSYEMWEINPSELTFMKE-LGCGQFGQVRLGKWRAQHKVAIKFIREGAMSEEDFIEEAKIMMKLSHPKLVQLYGVCSQQKPIYIVTEFMEHGSLLHFLQRGRGGFSLGSLLSISLDVC----EGMEYLEAHGFIHRDLASRNCLVND----SLAVKVSDFGMTRFVLDDQYTSSSGARFPVKWSPPEVFNFCKYSSKSDVWSYGVLMWEVFT-EGRMPFDNNLNHEVVTLVMQGHRLYKPKLATPTLYEIMHLCWKERPEDRPSFSRLCVMLSDTLE 633          

Query:   97 RMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLD---NKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEAS----------PPGPVDRR 555
            R+ KRSQ+K I S   YK + FVLT   L Y++     + K K ++ L+ ++ VE V++         K  FQI Y       + N LY+ A S + R  W+  ++   KD     L ++HP  W   G + CC  + ++++GC+E +          PP PV R+
Sbjct:   10 RLIKRSQQKKITSPLNYKERLFVLTKNKLTYYDGKPEKKFK-KGSIELSRIRCVEIVKNGGGTIPCQNKYPFQIVY-------DTNTLYVFAPSQSSRSIWVQSLKDEIKDN-QVVLVKFHPLFWLD-GAWLCCRQVEKQALGCEEYNLFGDITRKPLPPLPVKRQ 165          

Query:  850 AVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNS--LTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMR-DHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFR-RMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDY--FNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSI-YTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLD 2202
            A++++     + L L KG+ Y +V+ S++ W+  ++  G+ GY+P+NY+ +  S  L  + WY K + R +AE +L  E++ G F+VRDS S   TYT+SV +K P   G   + HYH    E       A    +YL+EKH F +I ++I YHKHN+ GLV RLR P  + D  +P TAG   + +E++P+EL      +G GQFG V+ G++R +  VA+K + EGAM+E+DFI+EAK M  L+HP LVQL+GV  +++PI I+TE+M+HGSL  FL+     +   +   +  D+C    +GM YLE   F+HRDLA+RNCLV      S+ VKV+DFGM RF+LD+ Y  S+G +FPV+W+PPEVF    Y+ K+DVWS+GVLMWEVFT     P+    N +V   ++ G RL KP +    LY +M  CW+  P+ RP+F  +C  + D L+
Sbjct:  236 ALYDFPATEPHDLRLIKGDEYIIVERSDANWFKARNHYGEEGYIPSNYVTEKISGNLVQYGWYSKQVNRNKAEELLRNEDKAGAFMVRDS-STPGTYTVSVYTKAPAGDGGGAIKHYHIKKTE-------ASPPQFYLAEKHLFYSIPELIEYHKHNAAGLVTRLRYPVGKPDKSAPSTAGFSYEMWEINPSELTFMKE-LGCGQFGQVRLGKWRAQHKVAIKFIREGAMSEEDFIEEAKIMMKLSHPKLVQLYGVCSQQKPIYIVTEFMEHGSLLHFLQRGRGGFSLGSLLSISLDVC----EGMEYLEAHGFIHRDLASRNCLVND----SLAVKVSDFGMTRFVLDDQYTSSSGARFPVKWSPPEVFNFCKYSSKSDVWSYGVLMWEVFT-EGRMPFDNNLNHEVVTLVMQGHRLYKPKLATPTLYEIMHLCWKERPEDRPSFSRLCVMLSDTLE 675          

Query:   97 RMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLD---NKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEAS----------PPGPVDRR 555
            R+ KRSQ+K I S   YK + FVLT   L Y++     + K K ++ L+ ++ VE V++         K  FQI Y       + N LY+ A S + R  W+  ++   KD     L ++HP  W   G + CC  + ++++GC+E +          PP PV R+
Sbjct:   52 RLIKRSQQKKITSPLNYKERLFVLTKNKLTYYDGKPEKKFK-KGSIELSRIRCVEIVKNGGGTIPCQNKYPFQIVY-------DTNTLYVFAPSQSSRSIWVQSLKDEIKDN-QVVLVKFHPLFWLD-GAWLCCRQVEKQALGCEEYNLFGDITRKPLPPLPVKRQ 207          

Query:   49 MLLNMMVSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMG 1389
            MLLNMMVSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSV QSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAG G
Sbjct:    1 MLLNMMVSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVVQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGHG 447          

Query:   61 MMVSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMG 1389
            MMVSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSV QSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAG G
Sbjct:    1 MMVSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVVQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGHG 443          

Query:   64 MVSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVAQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMG 1389
            MVSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSV QSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAG G
Sbjct:    1 MVSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDILSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEASPPGPVDRRNSSNTNGNFGERIVAAALANQGNGIEALGSILGNTHSNISENPPQSNTSVVQSMPTANSSMLQPINASQRKTHTNVNVSQKPAAINIEGDENSDKWVIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGHG 442          

Query:  811 NIEGDENSDKW----VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCEN 2217
            ++E   N+ KW    V+A++++ P++  QL L KGERY ++D S+  WWY++   G+ GYVP +++ + ++    DW+Y D++RQQAES L EE REGCF+VR S +     TLSV +K    +G L+VHHY      V        S  +YLSEKH + +++++I YHKHN+GGLV RLRS P R+ + P++ G+GLDEFE+D  +L+L+ + IG+GQFGVVK+GEFR M VAVKQMVEGAMNE+DFIDEA+NMRFLNHPNLV+LFGVV+K RPIMIITEYMKHGS+RDFLR   ++Y+N+  +L+D CAQVAKGMAYL+  NFVHRDLAARNCLVK+V RRS+QVKVADFGMARFLLDNVYE SAGTKFPVRWA PEVFQ+IYT +ADVWSFG+LMWEVFT C +NPY+G++N+QVYQYI+GGGRL KP  CPDRLYVLMLECWQH+P KRP F+Y+  KI D+LDQNC+N
Sbjct:  162 SVESRNNTVKWELESVVALYSFTPIQTGQLQLVKGERYTLIDCSHPDWWYMRDNYGEMGYVPRSHVQREDNFCNHDWFYGDVSRQQAESQLYEEGREGCFIVRCSSTGDTGLTLSVLTK---QSGSLRVHHYRIRQQGV--------SGPFYLSEKHLWPSVTELIEYHKHNAGGLVVRLRSVPSRNRDCPISLGVGLDEFEVDVNDLRLDKSAIGQGQFGVVKRGEFRNMQVAVKQMVEGAMNEEDFIDEARNMRFLNHPNLVRLFGVVLKTRPIMIITEYMKHGSMRDFLRANCNEYWNKSGILSDACAQVAKGMAYLDQRNFVHRDLAARNCLVKSVDRRSLQVKVADFGMARFLLDNVYESSAGTKFPVRWAAPEVFQAIYTTRADVWSFGILMWEVFTTCMQNPYNGQSNAQVYQYILGGGRLAKPPNCPDRLYVLMLECWQHEPTKRPGFQYISSKITDFLDQNCDN 623          

Query:   67 VSSDQELKISRMCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDI--LSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEA-SPPGPVDRRNSS 564
            ++ +QELK SRM ++SQ K  FSR  YKL+EFVLT  +LKYF+IS   RGK K  L L+ +KF+EKV ++DLDNK NVFQI YV D    S N  +LYIV+N   ER+DWI L++ YAK +LA F PRYHPG+W +PG+YSCC+D  R SMGC+   S    V+ RN++
Sbjct:    1 MNDEQELKSSRMYQKSQNKKFFSRANYKLREFVLTGMHLKYFDISNNARGKLKDRLNLSSIKFIEKVLNDDLDNKSNVFQIGYVMDDNGGSYNLVVLYIVSNCDEEREDWIQLLKIYAKIQLAVFQPRYHPGVWIRPGKYSCCEDGYRWSMGCELVISNDSSVESRNNT 169          

Query:  811 NIEGDENSDKW----VIAVHNYNPVRENQLPLQKGERYFVVDSSNSQWWYVKSAAGDAGYVPTNYIHKPNSLTTFDWYYKDLTRQQAESILLEENREGCFLVRDSVSKKNTYTLSVTSKDPENAGKLKVHHYHFHHIEVLSADGGAPSYMYYLSEKHAFQTISDVIHYHKHNSGGLVKRLRSPPMRDHESPVTAGMGLDEFELDPAELKLNSTPIGKGQFGVVKKGEFRRMPVAVKQMVEGAMNEDDFIDEAKNMRFLNHPNLVQLFGVVMKKRPIMIITEYMKHGSLRDFLRNRSSDYFNRPVVLADICAQVAKGMAYLELENFVHRDLAARNCLVKTVSRRSVQVKVADFGMARFLLDNVYEPSAGTKFPVRWAPPEVFQSIYTPKADVWSFGVLMWEVFTCCTENPYHGKNNSQVYQYIIGGGRLTKPVVCPDRLYVLMLECWQHDPKKRPAFEYVCQKIGDYLDQNCEN 2217
            ++E   N+ KW    V+A++++ P++  QL L KGERY ++D S+  WWY++   G+ GYVP +++ + ++    DW+Y D++RQQAES L EE REGCF+VR S +     TLSV +K    +G L+VHHY      V        S  +YLSEKH + +++++I YHKHN+GGLV RLRS P R+ + P++ G+GLDEFE+D  +L+L+ + IG+GQFGVVK+GEFR M VAVKQMVEGAMNE+DFIDEA+NMRFLNHPNLV+LFGVV+K RPIMIITEYMKHGS+RDFLR   ++Y+N+  +L+D CAQVAKGMAYL+  NFVHRDLAARNCLVK+V RRS+QVKVADFGMARFLLDNVYE SAGTKFPVRWA PEVFQ+IYT +ADVWSFG+LMWEVFT C +NPY+G++N+QVYQYI+GGGRL KP  CPDRLYVLMLECWQH+P KRP F+Y+  KI D+LDQNC+N
Sbjct:  151 SVESRNNTVKWELESVVALYSFTPIQTGQLQLVKGERYTLIDCSHPDWWYMRDNYGEMGYVPRSHVQREDNFCNHDWFYGDVSRQQAESQLYEEGREGCFIVRCSSTGDTGLTLSVLTK---QSGSLRVHHYRIRQQGV--------SGPFYLSEKHLWPSVTELIEYHKHNAGGLVVRLRSVPSRNRDCPISLGVGLDEFEVDVNDLRLDKSAIGQGQFGVVKRGEFRNMQVAVKQMVEGAMNEEDFIDEARNMRFLNHPNLVRLFGVVLKTRPIMIITEYMKHGSMRDFLRANCNEYWNKSGILSDACAQVAKGMAYLDQRNFVHRDLAARNCLVKSVDRRSLQVKVADFGMARFLLDNVYESSAGTKFPVRWAAPEVFQAIYTTRADVWSFGILMWEVFTTCMQNPYNGQSNAQVYQYILGGGRLAKPPNCPDRLYVLMLECWQHEPTKRPGFQYISSKITDFLDQNCDN 612          

Query:  100 MCKRSQRKNIFSRDCYKLKEFVLTPTYLKYFEISGGNRGKEKCTLLLNFLKFVEKVQDEDLDNKKNVFQIAYVEDI--LSTNRNILYIVANSAAERDDWINLIRYYAKDRLATFLPRYHPGIWKKPGRYSCCDDISRRSMGCQEA-SPPGPVDRRNSS 564
            M ++SQ K  FSR  YKL+EFVLT  +LKYF+IS   RGK K  L L+ +KF+EKV ++DLDNK NVFQI YV D    S N  +LYIV+N   ER+DWI L++ YAK +LA F PRYHPG+W +PG+YSCC+D  R SMGC+   S    V+ RN++
Sbjct:    1 MYQKSQNKKFFSRANYKLREFVLTGMHLKYFDISNNARGKLKDRLNLSSIKFIEKVLNDDLDNKSNVFQIGYVMDDNGGSYNLVVLYIVSNCDEEREDWIQLLKIYAKIQLAVFQPRYHPGVWIRPGKYSCCEDGYRWSMGCELVISNDSSVESRNNT 158