fer3l-2 protein

Overview
Namefer3l-2 protein (AGZ94910.1)
Smed IDSMED30003742
Length (bp)598
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of fer3l-2 protein (SMED30003742) t-SNE clustered cells

Violin plots show distribution of expression levels for fer3l-2 protein (SMED30003742) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of fer3l-2 protein (SMED30003742) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for fer3l-2 protein (SMED30003742) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003742

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
tail regionSMED30003742h1SMcG0001334 SmedASXL_012767SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parenchymaSMED30003742h1SMcG0001334 dd_Smed_v4_10868_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
progenitor cellSMED30003742h1SMcG0001334 KF487095smed_ncbi_20240424PMID:24173799
Cowles et al., 2013		whole organism asexual adult colorimetric in situ hybridization evidence
stem cellSMED30003742h1SMcG0001334 KF487095smed_ncbi_20240424PMID:24173799
Cowles et al., 2013		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30003742h1SMcG0001334 KF487095smed_ncbi_20240424PMID:24173799
Cowles et al., 2013		whole organism asexual adult colorimetric in situ hybridization evidence
body wall musculatureSMED30003742h1SMcG0001334 dd_Smed_v4_10868_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of fer3l-2 protein vs. Ensembl Human
Match: FERD3L (Fer3 like bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:16660])

HSP 1 Score: 104.375 bits (259), Expect = 7.492e-28
Identity = 51/67 (76.12%), Postives = 58/67 (86.57%), Query Frame = 3 
Query:  339 KPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            +PKR+R  T  QR AANIRER+RM NLN+AFD+LR+ VPTFAYEK+LSRIETLRLAI YISFMTE L
Sbjct:   91 RPKRKRVITYAQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELL 157
[Close]
BLAST of fer3l-2 protein vs. Ensembl Human
Match: PTF1A (pancreas associated transcription factor 1a [Source:HGNC Symbol;Acc:HGNC:23734])

HSP 1 Score: 76.2554 bits (186), Expect = 5.186e-16
Identity = 34/58 (58.62%), Postives = 47/58 (81.03%), Query Frame = 3 
Query:  375 RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINA 548
            R AAN+RERRRM ++N AF+ LR  +PT  YEK+LS+++TLRLAI YI+F++E L+ A
Sbjct:  165 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSE-LVQA 221
[Close]
BLAST of fer3l-2 protein vs. Ensembl Human
Match: SCX (scleraxis bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:32322])

HSP 1 Score: 64.6994 bits (156), Expect = 1.574e-12
Identity = 31/57 (54.39%), Postives = 41/57 (71.93%), Query Frame = 3 
Query:  372 QRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLI 542
            QRH AN RER R N++N AF  LR L+PT   +++LS+IETLRLA +YIS +   L+
Sbjct:   76 QRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLL 132
[Close]
BLAST of fer3l-2 protein vs. Ensembl Human
Match: ATOH1 (atonal bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:797])

HSP 1 Score: 64.6994 bits (156), Expect = 6.805e-12
Identity = 32/67 (47.76%), Postives = 48/67 (71.64%), Query Frame = 3 
Query:  369 EQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANP 569
            ++R AAN RERRRM+ LN AFD+LR ++P+F  +K+LS+ ETL++A  YI+ ++E L+  P     P
Sbjct:  159 QRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSE-LLQTPSGGEQP 224
[Close]
BLAST of fer3l-2 protein vs. Ensembl Human
Match: BHLHA15 (basic helix-loop-helix family member a15 [Source:HGNC Symbol;Acc:HGNC:22265])

HSP 1 Score: 60.8474 bits (146), Expect = 3.985e-11
Identity = 30/67 (44.78%), Postives = 46/67 (68.66%), Query Frame = 3 
Query:  342 PKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLI 542
            P  RR ++I++R  +N RER+RM+ LN AF  LR+++P    +K+LS+IETL LA  YI  +T  ++
Sbjct:   66 PGGRRDSSIQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATIL 132
[Close]
BLAST of fer3l-2 protein vs. Ensembl Celegans
Match: hlh-13 (Helix-loop-helix protein 13 [Source:UniProtKB/Swiss-Prot;Acc:Q20561])

HSP 1 Score: 68.5514 bits (166), Expect = 8.199e-15
Identity = 33/62 (53.23%), Postives = 46/62 (74.19%), Query Frame = 3 
Query:  369 EQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPE 554
            E+R  A+IRER+RM ++N AF  LR  +PTF YEK+LS+I+TL LAI YI+ M + ++  PE
Sbjct:   41 EERQTASIRERKRMCSINVAFIELRNYIPTFPYEKRLSKIDTLNLAIAYIN-MLDDVLRTPE 101
[Close]
BLAST of fer3l-2 protein vs. Ensembl Celegans
Match: lin-32 (pep chromosome:WBcel235:X:2229208:2230122:-1 gene:WBGene00003018.1 transcript:T14F9.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-32)

HSP 1 Score: 61.6178 bits (148), Expect = 2.897e-12
Identity = 35/80 (43.75%), Postives = 47/80 (58.75%), Query Frame = 3 
Query:  318 NSSNNSDKPKRRRTTTIE------QRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            N     DK K RR  T        +R AAN RERRRMN LN A+D LR+++P     K+LS+ ETL++A  YI  +++ L
Sbjct:   49 NGGGKDDKKKCRRYKTPSPQLLRMRRSAANERERRRMNTLNVAYDELREVLPEIDSGKKLSKFETLQMAQKYIECLSQIL 128
[Close]
BLAST of fer3l-2 protein vs. Ensembl Celegans
Match: ngn-1 (NeuroGeNin [Source:UniProtKB/TrEMBL;Acc:Q95XG7])

HSP 1 Score: 61.6178 bits (148), Expect = 6.542e-12
Identity = 36/89 (40.45%), Postives = 52/89 (58.43%), Query Frame = 3 
Query:  318 NSSNNSDKP----------KRRRTTTIEQ-----RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            NS N++ KP          ++R   TIE+     R  AN RERRRMN+LN A + LR ++P    E ++++IETLR A  YI+ ++ QL
Sbjct:   30 NSKNSTQKPVKREKRRYRCRKRSPATIERAKTVRRDKANARERRRMNSLNDALEHLRGILPALPDEPKMTKIETLRKAQEYIASLSFQL 118
[Close]
BLAST of fer3l-2 protein vs. Ensembl Celegans
Match: hlh-8 (Twist-related protein [Source:UniProtKB/Swiss-Prot;Acc:Q11094])

HSP 1 Score: 57.7658 bits (138), Expect = 1.644e-10
Identity = 29/61 (47.54%), Postives = 40/61 (65.57%), Query Frame = 3 
Query:  366 IEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINA 548
            ++QR  AN RER+R   LN AF  LR+L+P+   +K +S+I TLR+A  YISF+ E   N 
Sbjct:   19 VQQRACANRRERQRTKELNDAFTLLRKLIPSMPSDK-MSKIHTLRIATDYISFLDEMQKNG 78
[Close]
BLAST of fer3l-2 protein vs. Ensembl Celegans
Match: hlh-15 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q18590])

HSP 1 Score: 54.6842 bits (130), Expect = 4.609e-10
Identity = 27/50 (54.00%), Postives = 35/50 (70.00%), Query Frame = 3 
Query:  378 HAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFM 527
            HA   RER R+ + N AF +LR L+PT   EK+LS+IE LR +I YISF+
Sbjct:   37 HAT--RERIRVESFNMAFSQLRALLPTLPVEKKLSKIEILRFSIAYISFL 84
[Close]
BLAST of fer3l-2 protein vs. Ensembl Fly
Match: Fer3 (gene:FBgn0037937 transcript:FBtr0082435)

HSP 1 Score: 104.375 bits (259), Expect = 6.655e-28
Identity = 55/81 (67.90%), Postives = 64/81 (79.01%), Query Frame = 3 
Query:  309 GQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAP 551
            G+ N S++S K  RRR  ++ QR AANIRERRRM NLN+AFD+LR+ VPTFAYEK+LSRIETLRLAITYI FM E L   P
Sbjct:   66 GRANGSSSSSKKTRRRVASMAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLAITYIGFMAELLSGTP 146
[Close]
BLAST of fer3l-2 protein vs. Ensembl Fly
Match: Fer1 (gene:FBgn0037475 transcript:FBtr0081567)

HSP 1 Score: 84.7297 bits (208), Expect = 5.971e-20
Identity = 47/115 (40.87%), Postives = 76/115 (66.09%), Query Frame = 3 
Query:  219 ATNSSIANKYY----PHASNYDYRLNSFMAGQLLGQYNSSNN--SDKPKRRRTTT--IEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            ATN+S ++  Y     H+S  D   +++ +G    Q N+     S KP+R +  +   +QR AAN+RERRRM ++N+AF+ LR  +PT  YEK+LS+++TL+LAI+YI+F++E +
Sbjct:   23 ATNASTSSSDYFFGDEHSSESDDEDDAYSSGFNSDQENTEKTRRSHKPRRLKCASQMAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITFLSEMV 137
[Close]
BLAST of fer3l-2 protein vs. Ensembl Fly
Match: Fer1 (gene:FBgn0037475 transcript:FBtr0334670)

HSP 1 Score: 84.3445 bits (207), Expect = 1.111e-19
Identity = 48/120 (40.00%), Postives = 77/120 (64.17%), Query Frame = 3 
Query:  219 ATNSSIANKYY----PHASNYDYRLNSFMAGQLLGQYNS-------SNNSDKPKRRRTTT--IEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            ATN+S ++  Y     H+S  D   +++ +G    Q N+       S  S KP+R +  +   +QR AAN+RERRRM ++N+AF+ LR  +PT  YEK+LS+++TL+LAI+YI+F++E +
Sbjct:   23 ATNASTSSSDYFFGDEHSSESDDEDDAYSSGFNSDQENTEKTFCPFSRRSHKPRRLKCASQMAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITFLSEMV 142
[Close]
BLAST of fer3l-2 protein vs. Ensembl Fly
Match: Fer2 (gene:FBgn0038402 transcript:FBtr0301709)

HSP 1 Score: 74.3294 bits (181), Expect = 5.920e-16
Identity = 36/57 (63.16%), Postives = 46/57 (80.70%), Query Frame = 3 
Query:  372 QRHAANIRERRRM-NNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            QR AAN+RER+R+ +++N AFD LR  VPTF YEK+LS+I+TLRLAI YIS + E L
Sbjct:  148 QRQAANVRERKRIQSSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVL 204
[Close]
BLAST of fer3l-2 protein vs. Ensembl Fly
Match: Fer2 (gene:FBgn0038402 transcript:FBtr0344012)

HSP 1 Score: 74.3294 bits (181), Expect = 6.156e-16
Identity = 36/57 (63.16%), Postives = 46/57 (80.70%), Query Frame = 3 
Query:  372 QRHAANIRERRRM-NNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            QR AAN+RER+R+ +++N AFD LR  VPTF YEK+LS+I+TLRLAI YIS + E L
Sbjct:  148 QRQAANVRERKRIQSSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVL 204
[Close]
BLAST of fer3l-2 protein vs. Ensembl Zebrafish
Match: ferd3l (Fer3-like bHLH transcription factor [Source:ZFIN;Acc:ZDB-GENE-081104-461])

HSP 1 Score: 100.908 bits (250), Expect = 8.912e-28
Identity = 49/67 (73.13%), Postives = 58/67 (86.57%), Query Frame = 3 
Query:  339 KPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            KPKR+R  +  QR AANIRER+RM +LN+AFDRLR+ VPTFAYEK+LSRIETLRLAI YI+FMT+ L
Sbjct:   14 KPKRKRVISTVQRQAANIRERKRMFSLNEAFDRLRRRVPTFAYEKRLSRIETLRLAIVYIAFMTDIL 80
[Close]
BLAST of fer3l-2 protein vs. Ensembl Zebrafish
Match: si:dkey-34f9.3 (si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-410])

HSP 1 Score: 81.6481 bits (200), Expect = 2.383e-19
Identity = 38/64 (59.38%), Postives = 51/64 (79.69%), Query Frame = 3 
Query:  372 QRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKA 563
            QRHAANIRER+RM ++N AF+ LR  VPTF YEK+LS+I+TLRLAI YI+ + E L++  + K+
Sbjct:   66 QRHAANIRERKRMLSINSAFEELRCHVPTFPYEKRLSKIDTLRLAIAYIALLREILLSGCDPKS 129
[Close]
BLAST of fer3l-2 protein vs. Ensembl Zebrafish
Match: ptf1a (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:368662])

HSP 1 Score: 76.6406 bits (187), Expect = 9.893e-17
Identity = 40/86 (46.51%), Postives = 58/86 (67.44%), Query Frame = 3 
Query:  339 KPKRRRTTTIEQ---RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANPAAQLNQ 587
            K +RR  + +E    R AAN+RERRRM ++N AF+ LR  +PT  YEK+LS+++TLRLAI YI+F+ E + +   I+   +  LNQ
Sbjct:  102 KRRRRMRSEVEMQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELVQSDMPIRNPHSDALNQ 187
[Close]
BLAST of fer3l-2 protein vs. Ensembl Zebrafish
Match: AL807792.2 (pep chromosome:GRCz11:CHR_ALT_CTG8_2_5:29594098:29599935:1 gene:ENSDARG00000110597.1 transcript:ENSDART00000185012.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL807792.2)

HSP 1 Score: 72.4034 bits (176), Expect = 5.766e-15
Identity = 35/78 (44.87%), Postives = 53/78 (67.95%), Query Frame = 3 
Query:  342 PKRRRTTTIEQ--RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANP 569
            P  + T  +++  R AAN RERRRM+ LN AFD LR ++P F  +K+LS+ ETL++A  YI+ +++ L+  P  KA+P
Sbjct:  107 PSSKSTNVVQKQRRMAANARERRRMHGLNHAFDELRSVIPAFDNDKKLSKYETLQMAQIYINALSD-LLQGPGAKADP 183
[Close]
BLAST of fer3l-2 protein vs. Ensembl Zebrafish
Match: AL807792.3 (pep chromosome:GRCz11:CHR_ALT_CTG8_1_14:29595591:29601428:1 gene:ENSDARG00000111472.1 transcript:ENSDART00000192184.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL807792.3)

HSP 1 Score: 72.4034 bits (176), Expect = 5.766e-15
Identity = 35/78 (44.87%), Postives = 53/78 (67.95%), Query Frame = 3 
Query:  342 PKRRRTTTIEQ--RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANP 569
            P  + T  +++  R AAN RERRRM+ LN AFD LR ++P F  +K+LS+ ETL++A  YI+ +++ L+  P  KA+P
Sbjct:  107 PSSKSTNVVQKQRRMAANARERRRMHGLNHAFDELRSVIPAFDNDKKLSKYETLQMAQIYINALSD-LLQGPGAKADP 183
[Close]
BLAST of fer3l-2 protein vs. Ensembl Xenopus
Match: ferd3l (Fer3-like bHLH transcription factor [Source:NCBI gene;Acc:100124312])

HSP 1 Score: 105.145 bits (261), Expect = 1.111e-28
Identity = 52/70 (74.29%), Postives = 59/70 (84.29%), Query Frame = 3 
Query:  339 KPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINA 548
            +PKR+R  T  QR AANIRER+RM NLN+AFD LR+ VPTFAYEK+LSRIETLRLAI YISFMTE L N+
Sbjct:   55 RPKRKRVITYAQRQAANIRERKRMFNLNEAFDLLRKKVPTFAYEKRLSRIETLRLAIVYISFMTEMLKNS 124
[Close]
BLAST of fer3l-2 protein vs. Ensembl Xenopus
Match: ENSXETT00000031930.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:9:55646956:55647657:1 gene:ENSXETG00000008961.1 transcript:ENSXETT00000031930.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.7221 bits (195), Expect = 1.895e-18
Identity = 53/140 (37.86%), Postives = 76/140 (54.29%), Query Frame = 3 
Query:  120 PNLDFNLGNQNKIETSFYNYPTDMFCSYAFPNSATNSSIANKYYPHASNYDYRLNSFMAGQLLGQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            P  D+ L +Q  +E++F  +     C+  F  + T    A   +P  S     +   +AG L  + NSS   +            R AANIRERRRM ++N AF+ LR  VPTF YEK+LS+I+TLRLAI YI+ +++ L
Sbjct:    8 PEPDYQLWDQ--LESTFQLHSEPESCTMDFFPAVTEHVPA---WPALSQVVSEVPLQLAG-LGAEMNSSFQEESLMEGPCKV--HRQAANIRERRRMLSINSAFEELRGRVPTFPYEKRLSKIDTLRLAIAYIALLSDIL 139
[Close]
BLAST of fer3l-2 protein vs. Ensembl Xenopus
Match: PTF1A (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:100494161])

HSP 1 Score: 75.0998 bits (183), Expect = 9.597e-16
Identity = 37/68 (54.41%), Postives = 51/68 (75.00%), Query Frame = 3 
Query:  345 KRRR----TTTIEQ-RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTE 533
            KRRR       ++Q R AAN+RERRRM ++N AF+ LR  +PT  YEK+LS+++TLRLAI YI+F++E
Sbjct:  156 KRRRRLRSDAEMQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSE 223
[Close]
BLAST of fer3l-2 protein vs. Ensembl Xenopus
Match: tcf15 (transcription factor 15 [Source:NCBI gene;Acc:549260])

HSP 1 Score: 67.0106 bits (162), Expect = 1.201e-13
Identity = 39/91 (42.86%), Postives = 52/91 (57.14%), Query Frame = 3 
Query:  300 QLLGQYNSSNNSDKPKRRRTT----------TIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLI 542
            Q  G Y SS     PKRR+             ++QR AAN RER R  ++N AF  LR L+PT   +++LS+IETLRLA +YIS +   L+
Sbjct:   34 QSFGCYQSS-----PKRRKVGGTGGTGGGQPVVKQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYISHLANVLL 119
[Close]
BLAST of fer3l-2 protein vs. Ensembl Xenopus
Match: hnrnpc (heterogeneous nuclear ribonucleoprotein C (C1/C2) [Source:Xenbase;Acc:XB-GENE-489141])

HSP 1 Score: 67.0106 bits (162), Expect = 1.933e-13
Identity = 39/91 (42.86%), Postives = 52/91 (57.14%), Query Frame = 3 
Query:  300 QLLGQYNSSNNSDKPKRRRTT----------TIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLI 542
            Q  G Y SS     PKRR+             ++QR AAN RER R  ++N AF  LR L+PT   +++LS+IETLRLA +YIS +   L+
Sbjct:   34 QSFGCYQSS-----PKRRKVGGTGGTGGGQPVVKQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYISHLANVLL 119
[Close]
BLAST of fer3l-2 protein vs. Ensembl Mouse
Match: Ferd3l (Fer3 like bHLH transcription factor [Source:MGI Symbol;Acc:MGI:2150010])

HSP 1 Score: 105.531 bits (262), Expect = 1.793e-28
Identity = 54/86 (62.79%), Postives = 67/86 (77.91%), Query Frame = 3 
Query:  309 GQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKAN 566
            G+   ++   +PKR+R  T  QR AANIRER+RM NLN+AFD+LR+ VPTFAYEK+LSRIETLRLAI YISFMTE L +  E +A+
Sbjct:   83 GRGRVASLLGRPKRKRVITYAQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLQSKEEKEAS 168
[Close]
BLAST of fer3l-2 protein vs. Ensembl Mouse
Match: Ptf1a (pancreas specific transcription factor, 1a [Source:MGI Symbol;Acc:MGI:1328312])

HSP 1 Score: 76.2554 bits (186), Expect = 3.450e-16
Identity = 36/67 (53.73%), Postives = 51/67 (76.12%), Query Frame = 3 
Query:  351 RRTTTIEQ-RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINA 548
            R    ++Q R AAN+RERRRM ++N AF+ LR  +PT  YEK+LS+++TLRLAI YI+F++E L+ A
Sbjct:  153 RSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSE-LVQA 218
[Close]
BLAST of fer3l-2 protein vs. Ensembl Mouse
Match: Atoh1 (atonal bHLH transcription factor 1 [Source:MGI Symbol;Acc:MGI:104654])

HSP 1 Score: 67.0106 bits (162), Expect = 7.827e-13
Identity = 32/67 (47.76%), Postives = 49/67 (73.13%), Query Frame = 3 
Query:  369 EQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANP 569
            ++R AAN RERRRM+ LN AFD+LR ++P+F  +K+LS+ ETL++A  YI+ ++E L+  P +   P
Sbjct:  156 QRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSE-LLQTPNVGEQP 221
[Close]
BLAST of fer3l-2 protein vs. Ensembl Mouse
Match: Scx (scleraxis [Source:MGI Symbol;Acc:MGI:102934])

HSP 1 Score: 65.0846 bits (157), Expect = 1.124e-12
Identity = 31/57 (54.39%), Postives = 41/57 (71.93%), Query Frame = 3 
Query:  372 QRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLI 542
            QRH AN RER R N++N AF  LR L+PT   +++LS+IETLRLA +YIS +   L+
Sbjct:   79 QRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLL 135
[Close]
BLAST of fer3l-2 protein vs. Ensembl Mouse
Match: Tcf15 (transcription factor 15 [Source:MGI Symbol;Acc:MGI:104664])

HSP 1 Score: 63.1586 bits (152), Expect = 4.651e-12
Identity = 34/88 (38.64%), Postives = 49/88 (55.68%), Query Frame = 3 
Query:  279 LNSFMAGQLLGQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLI 542
            L +   G   G    ++N   P       + QR AAN RER R  ++N AF  LR L+PT   +++LS+IETLRLA +YI+ +   L+
Sbjct:   44 LEAARRGPGPGSGRRASNGAGP----VVVVRQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLL 127
[Close]
BLAST of fer3l-2 protein vs. UniProt/SwissProt
Match: sp|Q923Z4|FER3L_MOUSE (Fer3-like protein OS=Mus musculus OX=10090 GN=Ferd3l PE=1 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 1.254e-27
Identity = 54/86 (62.79%), Postives = 67/86 (77.91%), Query Frame = 3 
Query:  309 GQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKAN 566
            G+   ++   +PKR+R  T  QR AANIRER+RM NLN+AFD+LR+ VPTFAYEK+LSRIETLRLAI YISFMTE L +  E +A+
Sbjct:   83 GRGRVASLLGRPKRKRVITYAQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLQSKEEKEAS 168
[Close]
BLAST of fer3l-2 protein vs. UniProt/SwissProt
Match: sp|Q96RJ6|FER3L_HUMAN (Fer3-like protein OS=Homo sapiens OX=9606 GN=FERD3L PE=1 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 3.598e-27
Identity = 51/67 (76.12%), Postives = 58/67 (86.57%), Query Frame = 3 
Query:  339 KPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            +PKR+R  T  QR AANIRER+RM NLN+AFD+LR+ VPTFAYEK+LSRIETLRLAI YISFMTE L
Sbjct:   91 RPKRKRVITYAQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELL 157
[Close]
BLAST of fer3l-2 protein vs. UniProt/SwissProt
Match: sp|Q9VGJ5|FER3_DROME (Protein Fer3 OS=Drosophila melanogaster OX=7227 GN=fer3 PE=2 SV=2)

HSP 1 Score: 104.375 bits (259), Expect = 6.671e-27
Identity = 55/81 (67.90%), Postives = 64/81 (79.01%), Query Frame = 3 
Query:  309 GQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAP 551
            G+ N S++S K  RRR  ++ QR AANIRERRRM NLN+AFD+LR+ VPTFAYEK+LSRIETLRLAITYI FM E L   P
Sbjct:   66 GRANGSSSSSKKTRRRVASMAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLAITYIGFMAELLSGTP 146
[Close]
BLAST of fer3l-2 protein vs. UniProt/SwissProt
Match: sp|Q7ZSX3|PTF1A_DANRE (Pancreas transcription factor 1 subunit alpha OS=Danio rerio OX=7955 GN=ptf1a PE=2 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 7.468e-16
Identity = 40/86 (46.51%), Postives = 58/86 (67.44%), Query Frame = 3 
Query:  339 KPKRRRTTTIEQ---RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANPAAQLNQ 587
            K +RR  + +E    R AAN+RERRRM ++N AF+ LR  +PT  YEK+LS+++TLRLAI YI+F+ E + +   I+   +  LNQ
Sbjct:  102 KRRRRMRSEVEMQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELVQSDMPIRNPHSDALNQ 187
[Close]
BLAST of fer3l-2 protein vs. UniProt/SwissProt
Match: sp|Q4ZHW1|PTF1A_XENLA (Pancreas transcription factor 1 subunit alpha OS=Xenopus laevis OX=8355 GN=ptf1a PE=2 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 1.691e-15
Identity = 37/70 (52.86%), Postives = 52/70 (74.29%), Query Frame = 3 
Query:  345 KRRR----TTTIEQ-RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            KRRR       ++Q R AAN+RERRRM ++N AF+ LR  +PT  YEK+LS+++TLRLAI YI+F++E +
Sbjct:  106 KRRRRLRSDAEMQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSEMV 175
[Close]
BLAST of fer3l-2 protein vs. TrEMBL
Match: U5YTM0 (Fer3l-2 protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=fer3l-2 PE=2 SV=1)

HSP 1 Score: 330.487 bits (846), Expect = 8.363e-114
Identity = 161/162 (99.38%), Postives = 161/162 (99.38%), Query Frame = 3 
Query:   18 STEMTEINRLYRSDGVYNTCFPSSDLNQSLNNLYPNLDFNLGNQNKIETSFYNYPTDMFCSYAFPNSATNSSIANKYYPHASNYDYRLNSFMAGQLLGQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRL 503
            STEMTEINRLYRSDGVYNTCFPSSDLNQSLNNLYPNLDFNLGNQNKIETSFYNYPTDMFCSYAFPNSATNSSI NKYYPHASNYDYRLNSFMAGQLLGQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRL
Sbjct:    1 STEMTEINRLYRSDGVYNTCFPSSDLNQSLNNLYPNLDFNLGNQNKIETSFYNYPTDMFCSYAFPNSATNSSITNKYYPHASNYDYRLNSFMAGQLLGQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRL 162
[Close]
BLAST of fer3l-2 protein vs. TrEMBL
Match: A0A5N4A372 (Uncharacterized protein OS=Photinus pyralis OX=7054 GN=PPYR_03552 PE=4 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 4.727e-28
Identity = 61/87 (70.11%), Postives = 66/87 (75.86%), Query Frame = 3 
Query:  309 GQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINA-PEIKAN 566
            G  N+   S K  RRR  TI QR AANIRERRRM NLN+AFD+LR+ VPTFAYEK+LSRIETLRLAITYISFMTE L    PE K N
Sbjct:   82 GSPNNPTQSQKKPRRRVATIAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLAITYISFMTELLHGTNPEHKGN 168
[Close]
BLAST of fer3l-2 protein vs. TrEMBL
Match: B0WUK4 (N-twist OS=Culex quinquefasciatus OX=7176 GN=6043403 PE=4 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 4.733e-28
Identity = 62/110 (56.36%), Postives = 78/110 (70.91%), Query Frame = 3 
Query:  228 SSIANKYYPHASNYDYRLNSFMAGQL--LGQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAP 551
            +SIA + +  A     ++ SF+A +L   G   +S +S K  RRR  ++ QR AANIRERRRM NLN+AFD+LR+ VPTFAYEK+LSRIETLRLAITYI FM+E L   P
Sbjct:    3 ASIAGRSHLRAIWPRQQVGSFVAQRLSPRGAQPASTSSSKKTRRRVASMAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLAITYIGFMSELLNGTP 112
[Close]
BLAST of fer3l-2 protein vs. TrEMBL
Match: U5YTA6 (Fer3l-1 protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=fer3l-1 PE=2 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 8.054e-28
Identity = 56/74 (75.68%), Postives = 64/74 (86.49%), Query Frame = 3 
Query:  318 NSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            NS N S+KPKR+R +T+ QR AANIRERRRM +LN+AFD LR+ VPTFAYEK+LSRIETLRLAITYI FMTE L
Sbjct:  107 NSPNPSNKPKRKRISTVAQRRAANIRERRRMYSLNEAFDSLRKRVPTFAYEKRLSRIETLRLAITYICFMTELL 180
[Close]
BLAST of fer3l-2 protein vs. TrEMBL
Match: A0A212FKK8 (Putative n-twist OS=Danaus plexippus plexippus OX=278856 GN=KGM_214649 PE=4 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 1.405e-27
Identity = 61/124 (49.19%), Postives = 79/124 (63.71%), Query Frame = 3 
Query:  225 NSSIANKYYPHASNYDYRLNSFMAGQLL--------------GQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPE 554
            NSS  ++  P+ S +D    S    ++L              G+ ++ +   K  RRR  ++ QR AANIRERRRM NLN+AFD+LR+ VPTFAYEK+LSRIETLRLAITYISFM E L  +P+
Sbjct:   12 NSSSGSEVSPYGSLWDAPPASVPYPEILAFPPADLVWSAAGCGRSSARSTPGKKPRRRVASVAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLAITYISFMCELLHGSPQ 135
[Close]
BLAST of fer3l-2 protein vs. Ensembl Cavefish
Match: ferd3l (Fer3-like bHLH transcription factor [Source:ZFIN;Acc:ZDB-GENE-081104-461])

HSP 1 Score: 98.5969 bits (244), Expect = 4.312e-27
Identity = 48/69 (69.57%), Postives = 58/69 (84.06%), Query Frame = 3 
Query:  327 NNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTE 533
            ++S + +R+R  T  QR AANIRER+RM +LN+AFD LR+ VPTFAYEK+LSRIETLRLAI YISFMTE
Sbjct:    1 SHSGRSRRKRVITTVQRQAANIRERKRMFSLNEAFDELRKKVPTFAYEKRLSRIETLRLAIVYISFMTE 69
[Close]
BLAST of fer3l-2 protein vs. Ensembl Cavefish
Match: si:dkey-34f9.3 (neurogenic differentiation factor 1-like [Source:NCBI gene;Acc:107197807])

HSP 1 Score: 82.4185 bits (202), Expect = 3.557e-19
Identity = 38/64 (59.38%), Postives = 52/64 (81.25%), Query Frame = 3 
Query:  372 QRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKA 563
            QRHAANIRER+RM ++N AF++LR  VPTF YEK+LS+I+TLRLAI YI+ + E L++  + K+
Sbjct:  121 QRHAANIRERKRMLSINSAFEQLRCHVPTFPYEKRLSKIDTLRLAIAYIALLREILMSGCDPKS 184
[Close]
BLAST of fer3l-2 protein vs. Ensembl Cavefish
Match: ptf1a (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:103046795])

HSP 1 Score: 77.7962 bits (190), Expect = 2.313e-17
Identity = 40/85 (47.06%), Postives = 59/85 (69.41%), Query Frame = 3 
Query:  339 KPKRRRTTTIEQ---RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANPAAQLN 584
            K +RR  + IE    R AAN+RERRRM ++N AF+ LR  +PT  YEK+LS+++TLRLAI YI+F+ E + +   I+++ +  LN
Sbjct:   79 KRRRRARSEIEAQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELVQSDAPIRSSSSEALN 163
[Close]
BLAST of fer3l-2 protein vs. Ensembl Cavefish
Match: tcf15 (transcription factor 15 [Source:NCBI gene;Acc:103040145])

HSP 1 Score: 67.781 bits (164), Expect = 5.007e-14
Identity = 36/73 (49.32%), Postives = 49/73 (67.12%), Query Frame = 3 
Query:  345 KRRRTTT-----IEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINA 548
            KRRR TT     ++QR+AAN RER R  ++N AF  LR L+PT   +++LS+IETLRLA +YIS +   L+  
Sbjct:   48 KRRRNTTGGVLIVKQRNAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYISHLANVLLTG 120
[Close]
BLAST of fer3l-2 protein vs. Ensembl Cavefish
Match: si:ch211-246m6.4 (transcription factor 15-like [Source:NCBI gene;Acc:103034626])

HSP 1 Score: 66.6254 bits (161), Expect = 2.032e-13
Identity = 32/73 (43.84%), Postives = 47/73 (64.38%), Query Frame = 3 
Query:  324 SNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLI 542
               + +P RR     +QR AAN RER R +++N AF  LR L+PT   +++LS+IETLRLA +YI+ +   L+
Sbjct:   62 GKRTHRPTRRLVGVSKQRQAANARERDRTHSVNTAFSALRTLIPTEPADRKLSKIETLRLASSYIAHLANVLL 134
[Close]
BLAST of fer3l-2 protein vs. Ensembl Sea Lamprey
Match: si:dkey-34f9.3 (si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-410])

HSP 1 Score: 76.6406 bits (187), Expect = 1.656e-18
Identity = 37/64 (57.81%), Postives = 50/64 (78.12%), Query Frame = 3 
Query:  372 QRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKA 563
            QR AAN+RERRRM ++N AF+ LR  VPTF YEK+LS+I+TLRLAI YI+ + + L++  + KA
Sbjct:   34 QRTAANVRERRRMLSINSAFEELRCHVPTFPYEKRLSKIDTLRLAIAYIALLRDILLSDTDPKA 97
[Close]
BLAST of fer3l-2 protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004072.1 (pep scaffold:Pmarinus_7.0:GL492732:1750:4325:-1 gene:ENSPMAG00000003727.1 transcript:ENSPMAT00000004072.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.9442 bits (180), Expect = 1.676e-16
Identity = 33/53 (62.26%), Postives = 42/53 (79.25%), Query Frame = 3 
Query:  375 RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTE 533
            R AAN RERRRM ++N AF+ LR  +PT  YEK+LS+++TLRLAI YISF+ E
Sbjct:  133 RQAANQRERRRMQSINAAFEGLRAHIPTLPYEKRLSKVDTLRLAIGYISFLGE 185
[Close]
BLAST of fer3l-2 protein vs. Ensembl Sea Lamprey
Match: TWIST1 (twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428])

HSP 1 Score: 61.2326 bits (147), Expect = 2.701e-12
Identity = 29/57 (50.88%), Postives = 42/57 (73.68%), Query Frame = 3 
Query:  369 EQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            +QR  AN+RER+R  +LN+AF  LRQ++PT   +K LS+I+TL+LA  YI F+ + L
Sbjct:   95 QQRFVANVRERQRTQSLNEAFASLRQIIPTLPSDK-LSKIQTLKLATRYIDFLYQVL 150
[Close]
BLAST of fer3l-2 protein vs. Ensembl Sea Lamprey
Match: TWIST1 (twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428])

HSP 1 Score: 61.2326 bits (147), Expect = 4.378e-12
Identity = 29/57 (50.88%), Postives = 42/57 (73.68%), Query Frame = 3 
Query:  369 EQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            +QR  AN+RER+R  +LN+AF  LRQ++PT   +K LS+I+TL+LA  YI F+ + L
Sbjct:  113 QQRFVANVRERQRTQSLNEAFASLRQIIPTLPSDK-LSKIQTLKLATRYIDFLYQVL 168
[Close]
BLAST of fer3l-2 protein vs. Ensembl Sea Lamprey
Match: neurod1 (neuronal differentiation 1 [Source:NCBI gene;Acc:30169])

HSP 1 Score: 58.9214 bits (141), Expect = 5.664e-11
Identity = 29/56 (51.79%), Postives = 40/56 (71.43%), Query Frame = 3 
Query:  372 QRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            +R  AN RER RM+ LN A D LR++VP ++  ++LS+IETLRLA  YI  ++E L
Sbjct:   24 RRVKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEIL 79
[Close]
BLAST of fer3l-2 protein vs. Ensembl Nematostella
Match: EDO43849 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXI0])

HSP 1 Score: 80.8777 bits (198), Expect = 1.065e-20
Identity = 35/58 (60.34%), Postives = 49/58 (84.48%), Query Frame = 3 
Query:  366 IEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            I QRHAAN+RER+RM ++N+AF+ LR+ +PT  YEK+LS+++TLRLAI YI F+TE +
Sbjct:    1 IVQRHAANLRERKRMQSINEAFEGLRKHIPTLPYEKRLSKVDTLRLAIGYIGFLTEMI 58
[Close]
BLAST of fer3l-2 protein vs. Ensembl Nematostella
Match: TWIST (Predicted protein; Twist family bHLH transcription factor [Source:UniProtKB/TrEMBL;Acc:Q6S5G7])

HSP 1 Score: 63.1586 bits (152), Expect = 3.243e-13
Identity = 32/66 (48.48%), Postives = 47/66 (71.21%), Query Frame = 3 
Query:  348 RRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLIN 545
            RR  +  +QR  AN+RER+R   LN+AF++LR+++PT   +K LS+I+TLRLA  YI F+ + L N
Sbjct:   29 RRGGSKNDQRAIANVRERQRTQALNEAFNKLRKIIPTLPSDK-LSKIQTLRLASRYIDFLCQVLGN 93
[Close]
BLAST of fer3l-2 protein vs. Ensembl Nematostella
Match: EDO42924 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZZ0])

HSP 1 Score: 61.2326 bits (147), Expect = 3.478e-13
Identity = 30/62 (48.39%), Postives = 46/62 (74.19%), Query Frame = 3 
Query:  369 EQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPE 554
            +QR AAN RER R +++N AF+ LR L+PT   +++LS+IETLRLA +YI+ ++  LI+  +
Sbjct:    1 KQRQAANARERNRTHSVNAAFNALRLLIPTEPSDRKLSKIETLRLASSYIAHLSTILISGTQ 62
[Close]
BLAST of fer3l-2 protein vs. Ensembl Nematostella
Match: EDO43666 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYA7])

HSP 1 Score: 56.9954 bits (136), Expect = 1.763e-11
Identity = 32/65 (49.23%), Postives = 38/65 (58.46%), Query Frame = 3 
Query:  351 RRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLIN 545
            R T    QR  AN RER R+  LN   DRLR L+P F  EK+ S+ ET+ LA  YI  MTE + N
Sbjct:    1 RLTGVSRQRRLANTRERHRVQVLNAYIDRLRHLIPLFPGEKKPSKTETVHLAALYIEHMTEIIQN 65
[Close]
BLAST of fer3l-2 protein vs. Ensembl Nematostella
Match: EDO43667 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYA8])

HSP 1 Score: 53.1434 bits (126), Expect = 5.336e-10
Identity = 30/65 (46.15%), Postives = 41/65 (63.08%), Query Frame = 3 
Query:  351 RRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLIN 545
            R T   +QR  AN RER R++ LN   DRL+ ++P F  EK  S+ ET+R+A  YI+ +TE L N
Sbjct:    8 RLTGVSKQRRLANARERSRVHTLNANIDRLKDILPLFPDEKP-SKTETIRIAAVYIAHLTELLEN 71
[Close]
BLAST of fer3l-2 protein vs. Ensembl Medaka
Match: ferd3l (Fer3 like bHLH transcription factor [Source:NCBI gene;Acc:101167882])

HSP 1 Score: 99.7525 bits (247), Expect = 1.414e-27
Identity = 49/70 (70.00%), Postives = 58/70 (82.86%), Query Frame = 3 
Query:  330 NSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            +  K +RRR  T+ QR AAN+RERRRM +LN+AFD LR+ VPTFAYEK+LSRIETLRLAI YISFMT+ L
Sbjct:    1 SQGKSRRRRIITVVQRQAANVRERRRMFSLNEAFDELRRKVPTFAYEKRLSRIETLRLAIVYISFMTDLL 70
[Close]
BLAST of fer3l-2 protein vs. Ensembl Medaka
Match: si:dkey-34f9.3 (si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-410])

HSP 1 Score: 80.8777 bits (198), Expect = 8.992e-19
Identity = 37/59 (62.71%), Postives = 48/59 (81.36%), Query Frame = 3 
Query:  372 QRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINA 548
            QRHAANIRER+RM ++N AF+ LR  VPTF YEK+LS+I+TLRLAI YI+ + E L++ 
Sbjct:  125 QRHAANIRERKRMLSINSAFEELRCHVPTFPYEKRLSKIDTLRLAIAYIALLREILLSG 183
[Close]
BLAST of fer3l-2 protein vs. Ensembl Medaka
Match: ptf1a (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:101160350])

HSP 1 Score: 75.0998 bits (183), Expect = 3.638e-16
Identity = 32/53 (60.38%), Postives = 43/53 (81.13%), Query Frame = 3 
Query:  375 RHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTE 533
            R AAN+RERRRM ++N AF+ LR  +PT  YEK+LS+++TLRLAI YI+F+ E
Sbjct:  120 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAE 172
[Close]
BLAST of fer3l-2 protein vs. Ensembl Medaka
Match: atoh7 (atonal bHLH transcription factor 7 [Source:NCBI gene;Acc:101155052])

HSP 1 Score: 67.3958 bits (163), Expect = 2.909e-14
Identity = 36/83 (43.37%), Postives = 56/83 (67.47%), Query Frame = 3 
Query:  330 NSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANPAAQ 578
            +S  P++  T T  +R AAN RER+RM  LN AFDRLR++VP +  +K+LS+ ETL++A++YI  ++ +++  P   A P  Q
Sbjct:   19 DSKSPEKYETAT-RRRMAANARERKRMQGLNTAFDRLRKVVPQWGQDKKLSKYETLQMALSYIMALS-RILTDPRRHAAPHRQ 99
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BLAST of fer3l-2 protein vs. Ensembl Medaka
Match: atoh1b (neurogenin-2 [Source:NCBI gene;Acc:101175327])

HSP 1 Score: 66.2402 bits (160), Expect = 3.627e-13
Identity = 32/59 (54.24%), Postives = 44/59 (74.58%), Query Frame = 3 
Query:  372 QRH---AANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            QRH   AAN RERRRM+ LNKAFD LR ++P+   EK+LS+ +TL++A  YI+ ++E L
Sbjct:   88 QRHRRVAANARERRRMHGLNKAFDELRSVIPSLENEKKLSKYDTLQMAQIYITELSELL 146
[Close]
BLAST of fer3l-2 protein vs. Planmine SMEST
Match: SMESG000019274.1 (SMESG000019274.1)

HSP 1 Score: 383.259 bits (983), Expect = 6.376e-138
Identity = 187/188 (99.47%), Postives = 187/188 (99.47%), Query Frame = 3 
Query:   27 MTEINRLYRSDGVYNTCFPSSDLNQSLNNLYPNLDFNLGNQNKIETSFYNYPTDMFCSYAFPNSATNSSIANKYYPHASNYDYRLNSFMAGQLLGQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANPAAQLNQK 590
            MTEINRLYRSDGVYNTCFPSSDLNQSLNNLYPNLDFNLGNQNKIETSFYNYPTDMFCSYAFPNSATNSSI NKYYPHASNYDYRLNSFMAGQLLGQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANPAAQLNQK
Sbjct:    1 MTEINRLYRSDGVYNTCFPSSDLNQSLNNLYPNLDFNLGNQNKIETSFYNYPTDMFCSYAFPNSATNSSITNKYYPHASNYDYRLNSFMAGQLLGQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANPAAQLNQK 188
[Close]
BLAST of fer3l-2 protein vs. Planmine SMEST
Match: SMESG000029000.1 (SMESG000029000.1)

HSP 1 Score: 112.849 bits (281), Expect = 6.572e-31
Identity = 56/74 (75.68%), Postives = 64/74 (86.49%), Query Frame = 3 
Query:  318 NSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            NS N S+KPKR+R +T+ QR AANIRERRRM +LN+AFD LR+ VPTFAYEK+LSRIETLRLAITYI FMTE L
Sbjct:  120 NSPNPSNKPKRKRISTVAQRRAANIRERRRMYSLNEAFDSLRKRVPTFAYEKRLSRIETLRLAITYICFMTELL 193
[Close]
BLAST of fer3l-2 protein vs. Planmine SMEST
Match: SMESG000029000.1 (SMESG000029000.1)

HSP 1 Score: 112.849 bits (281), Expect = 6.907e-31
Identity = 56/74 (75.68%), Postives = 64/74 (86.49%), Query Frame = 3 
Query:  318 NSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 539
            NS N S+KPKR+R +T+ QR AANIRERRRM +LN+AFD LR+ VPTFAYEK+LSRIETLRLAITYI FMTE L
Sbjct:  127 NSPNPSNKPKRKRISTVAQRRAANIRERRRMYSLNEAFDSLRKRVPTFAYEKRLSRIETLRLAITYICFMTELL 200
[Close]
BLAST of fer3l-2 protein vs. Planmine SMEST
Match: SMESG000062901.1 (SMESG000062901.1)

HSP 1 Score: 87.0409 bits (214), Expect = 4.520e-22
Identity = 51/94 (54.26%), Postives = 63/94 (67.02%), Query Frame = 3 
Query:  288 FMAGQLLGQYNSSNNS--DKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINA--PEI 557
            F   + L +Y+S+      K KRRR  +   R AANIRER+RM NLN AF+ LR  VPTF +EK+LSRIETLRLAI YI FM E ++N   P+I
Sbjct:   23 FSTVKELEKYDSTKCKKYQKQKRRRNKSTAHRTAANIRERKRMINLNAAFENLRLKVPTFVFEKRLSRIETLRLAIAYIKFM-ECILNGVWPKI 115
[Close]
BLAST of fer3l-2 protein vs. Planmine SMEST
Match: SMESG000079648.1 (SMESG000079648.1)

HSP 1 Score: 76.6406 bits (187), Expect = 5.007e-17
Identity = 37/79 (46.84%), Postives = 55/79 (69.62%), Query Frame = 3 
Query:  297 GQLLGQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTE 533
            G+L   ++S   +    RR    + QR AAN+RERRRM ++N+AF+ LR  +PT  YEK+LS+++TLRLAI YI+F+ +
Sbjct:   78 GKLGSGFSSKYRNRNKTRRGQKLVFQRQAANLRERRRMQSINEAFEGLRAHIPTLPYEKRLSKVDTLRLAIGYINFLQD 156
The following BLAST results are available for this feature:
BLAST of fer3l-2 protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FERD3L7.492e-2876.12Fer3 like bHLH transcription factor [Source:HGNC S... [more]
PTF1A5.186e-1658.62pancreas associated transcription factor 1a [Sourc... [more]
SCX1.574e-1254.39scleraxis bHLH transcription factor [Source:HGNC S... [more]
ATOH16.805e-1247.76atonal bHLH transcription factor 1 [Source:HGNC Sy... [more]
BHLHA153.985e-1144.78basic helix-loop-helix family member a15 [Source:H... [more]
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BLAST of fer3l-2 protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hlh-138.199e-1553.23Helix-loop-helix protein 13 [Source:UniProtKB/Swi... [more]
lin-322.897e-1243.75pep chromosome:WBcel235:X:2229208:2230122:-1 gene:... [more]
ngn-16.542e-1240.45NeuroGeNin [Source:UniProtKB/TrEMBL;Acc:Q95XG7][more]
hlh-81.644e-1047.54Twist-related protein [Source:UniProtKB/Swiss-Pro... [more]
hlh-154.609e-1054.00Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q18... [more]
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BLAST of fer3l-2 protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Fer36.655e-2867.90gene:FBgn0037937 transcript:FBtr0082435[more]
Fer15.971e-2040.87gene:FBgn0037475 transcript:FBtr0081567[more]
Fer11.111e-1940.00gene:FBgn0037475 transcript:FBtr0334670[more]
Fer25.920e-1663.16gene:FBgn0038402 transcript:FBtr0301709[more]
Fer26.156e-1663.16gene:FBgn0038402 transcript:FBtr0344012[more]
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BLAST of fer3l-2 protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ferd3l8.912e-2873.13Fer3-like bHLH transcription factor [Source:ZFIN;A... [more]
si:dkey-34f9.32.383e-1959.38si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-41... [more]
ptf1a9.893e-1746.51pancreas associated transcription factor 1a [Sourc... [more]
AL807792.25.766e-1544.87pep chromosome:GRCz11:CHR_ALT_CTG8_2_5:29594098:29... [more]
AL807792.35.766e-1544.87pep chromosome:GRCz11:CHR_ALT_CTG8_1_14:29595591:2... [more]
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BLAST of fer3l-2 protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ferd3l1.111e-2874.29Fer3-like bHLH transcription factor [Source:NCBI g... [more]
ENSXETT00000031930.11.895e-1837.86pep primary_assembly:Xenopus_tropicalis_v9.1:9:556... [more]
PTF1A9.597e-1654.41pancreas associated transcription factor 1a [Sourc... [more]
tcf151.201e-1342.86transcription factor 15 [Source:NCBI gene;Acc:5492... [more]
hnrnpc1.933e-1342.86heterogeneous nuclear ribonucleoprotein C (C1/C2) ... [more]
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BLAST of fer3l-2 protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ferd3l1.793e-2862.79Fer3 like bHLH transcription factor [Source:MGI Sy... [more]
Ptf1a3.450e-1653.73pancreas specific transcription factor, 1a [Source... [more]
Atoh17.827e-1347.76atonal bHLH transcription factor 1 [Source:MGI Sym... [more]
Scx1.124e-1254.39scleraxis [Source:MGI Symbol;Acc:MGI:102934][more]
Tcf154.651e-1238.64transcription factor 15 [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of fer3l-2 protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q923Z4|FER3L_MOUSE1.254e-2762.79Fer3-like protein OS=Mus musculus OX=10090 GN=Ferd... [more]
sp|Q96RJ6|FER3L_HUMAN3.598e-2776.12Fer3-like protein OS=Homo sapiens OX=9606 GN=FERD3... [more]
sp|Q9VGJ5|FER3_DROME6.671e-2767.90Protein Fer3 OS=Drosophila melanogaster OX=7227 GN... [more]
sp|Q7ZSX3|PTF1A_DANRE7.468e-1646.51Pancreas transcription factor 1 subunit alpha OS=D... [more]
sp|Q4ZHW1|PTF1A_XENLA1.691e-1552.86Pancreas transcription factor 1 subunit alpha OS=X... [more]
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BLAST of fer3l-2 protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
U5YTM08.363e-11499.38Fer3l-2 protein (Fragment) OS=Schmidtea mediterran... [more]
A0A5N4A3724.727e-2870.11Uncharacterized protein OS=Photinus pyralis OX=705... [more]
B0WUK44.733e-2856.36N-twist OS=Culex quinquefasciatus OX=7176 GN=60434... [more]
U5YTA68.054e-2875.68Fer3l-1 protein (Fragment) OS=Schmidtea mediterran... [more]
A0A212FKK81.405e-2749.19Putative n-twist OS=Danaus plexippus plexippus OX=... [more]
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BLAST of fer3l-2 protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ferd3l4.312e-2769.57Fer3-like bHLH transcription factor [Source:ZFIN;A... [more]
si:dkey-34f9.33.557e-1959.38neurogenic differentiation factor 1-like [Source:N... [more]
ptf1a2.313e-1747.06pancreas associated transcription factor 1a [Sourc... [more]
tcf155.007e-1449.32transcription factor 15 [Source:NCBI gene;Acc:1030... [more]
si:ch211-246m6.42.032e-1343.84transcription factor 15-like [Source:NCBI gene;Acc... [more]
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BLAST of fer3l-2 protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-34f9.31.656e-1857.81si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-41... [more]
ENSPMAT00000004072.11.676e-1662.26pep scaffold:Pmarinus_7.0:GL492732:1750:4325:-1 ge... [more]
TWIST12.701e-1250.88twist family bHLH transcription factor 1 [Source:H... [more]
TWIST14.378e-1250.88twist family bHLH transcription factor 1 [Source:H... [more]
neurod15.664e-1151.79neuronal differentiation 1 [Source:NCBI gene;Acc:3... [more]
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BLAST of fer3l-2 protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of fer3l-2 protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO438491.065e-2060.34Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
TWIST3.243e-1348.48Predicted protein; Twist family bHLH transcription... [more]
EDO429243.478e-1348.39Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO436661.763e-1149.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO436675.336e-1046.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of fer3l-2 protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ferd3l1.414e-2770.00Fer3 like bHLH transcription factor [Source:NCBI g... [more]
si:dkey-34f9.38.992e-1962.71si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-41... [more]
ptf1a3.638e-1660.38pancreas associated transcription factor 1a [Sourc... [more]
atoh72.909e-1443.37atonal bHLH transcription factor 7 [Source:NCBI ge... [more]
atoh1b3.627e-1354.24neurogenin-2 [Source:NCBI gene;Acc:101175327][more]
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BLAST of fer3l-2 protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000019274.16.376e-13899.47SMESG000019274.1[more]
SMESG000029000.16.572e-3175.68SMESG000029000.1[more]
SMESG000029000.16.907e-3175.68SMESG000029000.1[more]
SMESG000062901.14.520e-2254.26SMESG000062901.1[more]
SMESG000079648.15.007e-1746.84SMESG000079648.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30003742
GenBankAGZ94910.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003742 ID=SMED30003742|Name=fer3l-2 protein|organism=Schmidtea mediterranea sexual|type=transcript|length=598bp
AGAAAATTTTTATAGATTCGACTGAAATGACTGAAATCAATAGATTATAC
AGGTCTGATGGAGTCTACAATACTTGTTTTCCATCTTCCGATTTGAATCA
ATCTCTCAATAATCTTTATCCAAATTTAGATTTTAATTTGGGTAATCAGA
ATAAAATTGAAACATCATTTTATAATTATCCAACTGATATGTTTTGTTCC
TATGCATTTCCGAATTCGGCAACAAACTCCTCGATTGCCAATAAATATTA
TCCGCACGCTTCCAATTATGATTATAGATTGAACAGTTTCATGGCGGGTC
AATTGCTAGGTCAATACAATTCATCAAATAATTCCGATAAACCAAAACGT
CGGAGAACGACAACAATCGAACAGAGACATGCAGCTAACATAAGAGAACG
GAGAAGGATGAACAACCTCAATAAAGCTTTTGATAGACTGCGTCAGTTGG
TTCCGACTTTCGCTTATGAGAAACAGTTATCCAGAATTGAAACATTGCGG
TTGGCAATTACATATATCAGTTTTATGACAGAACAACTTATCAATGCTCC
TGAAATCAAAGCAAATCCCGCAGCCCAATTAAATCAAAAATAAGCGCA
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protein sequence of SMED30003742-orf-1

>SMED30003742-orf-1 ID=SMED30003742-orf-1|Name=SMED30003742-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=197bp
KIFIDSTEMTEINRLYRSDGVYNTCFPSSDLNQSLNNLYPNLDFNLGNQN
KIETSFYNYPTDMFCSYAFPNSATNSSIANKYYPHASNYDYRLNSFMAGQ
LLGQYNSSNNSDKPKRRRTTTIEQRHAANIRERRRMNNLNKAFDRLRQLV
PTFAYEKQLSRIETLRLAITYISFMTEQLINAPEIKANPAAQLNQK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0000122negative regulation of transcription from RNA polymerase II promoter
GO:0033504floor plate development
GO:0045892negative regulation of transcription, DNA-templated
GO:0048468cell development
GO:0050767regulation of neurogenesis
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0009790embryo development
GO:0009887animal organ morphogenesis
GO:0009888tissue development
GO:0030154cell differentiation
GO:0030902hindbrain development
GO:0031016pancreas development
GO:0031017exocrine pancreas development
GO:0035881amacrine cell differentiation
GO:0045893positive regulation of transcription, DNA-templated
GO:0048384retinoic acid receptor signaling pathway
GO:0048699generation of neurons
Vocabulary: molecular function
TermDefinition
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0043565sequence-specific DNA binding
GO:0003677DNA binding
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0046983protein dimerization activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000120progenitor cell
PLANA:0000121stem cell
PLANA:0000240body wall musculature
PLANA:0000421tail
PLANA:0002142parenchyma
Vocabulary: INTERPRO
TermDefinition
IPR036638HLH_DNA-bd_sf
IPR011598bHLH_dom
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005634nucleus
GO:0005667transcription factor complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 129..149
NoneNo IPR availablePANTHERPTHR23349:SF63FER3-LIKE PROTEINcoord: 106..183
NoneNo IPR availablePANTHERPTHR23349BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWISTcoord: 106..183
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainSMARTSM00353finuluscoord: 129..181
e-value: 1.6E-16
score: 70.9
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainPFAMPF00010HLHcoord: 124..175
e-value: 8.1E-18
score: 64.1
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainPROSITEPS50888BHLHcoord: 123..175
score: 16.437
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainCDDcd00083HLHcoord: 123..179
e-value: 5.78263E-18
score: 72.2467
IPR036638Helix-loop-helix DNA-binding domain superfamilyGENE3DG3DSA:4.10.280.10coord: 116..184
e-value: 5.9E-23
score: 82.1
IPR036638Helix-loop-helix DNA-binding domain superfamilySUPERFAMILYSSF47459HLH, helix-loop-helix DNA-binding domaincoord: 123..180