WSC domain-containing protein

Overview


Name	WSC domain-containing protein
Smed ID	SMED30003737
Length (bp)	605

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30003737

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30003737	SMESG000024496.1	dd_Smed_v4_36585_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30003737	SMESG000024496.1	dd_Smed_v4_36585_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30003737	SMESG000024496.1	dd_Smed_v4_36585_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of WSC domain-containing protein vs. Ensembl Zebrafish
Match: si:ch73-359m17.2 (si:ch73-359m17.2 [Source:ZFIN;Acc:ZDB-GENE-141222-90])

HSP 1 Score: 70.4774 bits (171), Expect = 4.856e-15
Identity = 42/126 (33.33%), Postives = 63/126 (50.00%), Query Frame = 2

Query:  128 NAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYN--RTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVY 499
            +AVDGNT  D ++ SC H+  E F  WW V L  VS + +V I +R DCC    R + + I  S EN  N + L++               K +     + + GR + +F P  +E ++ CEVEV+
Sbjct:   46 HAVDGNTEADYRKGSCTHTSRE-FNPWWRVDLGGVSSVNKVTITNRGDCCEERIRGAQIRIGDSLENNGNNNQLAATLLDA---------IKGSQTFEFQPIQGRYLNVFLPGNDETLSLCEVEVF 161

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BLAST of WSC domain-containing protein vs. Ensembl Zebrafish
Match: si:ch73-359m17.2 (si:ch73-359m17.2 [Source:ZFIN;Acc:ZDB-GENE-141222-90])

HSP 1 Score: 72.0182 bits (175), Expect = 9.863e-15
Identity = 43/129 (33.33%), Postives = 64/129 (49.61%), Query Frame = 2

Query:  128 NAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYN--RTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYP 508
            +AVDGNT  D ++ SC H+  E F  WW V L  VS + +V I +R DCC    R + + I  S EN  N + L++               K +     + + GR + +F P  +E ++ CEVEV+  P
Sbjct:   46 HAVDGNTEADYRKGSCTHTSRE-FNPWWRVDLGGVSSVNKVTITNRGDCCEERIRGAQIRIGDSLENNGNNNQLAATLLDA---------IKGSQTFEFQPIQGRYLNVFLPGNDETLSLCEVEVFSGP 164

HSP 2 Score: 58.151 bits (139), Expect = 8.075e-10
Identity = 43/127 (33.86%), Postives = 60/127 (47.24%), Query Frame = 2

Query:  125 SNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNR--TSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVY 499
             NAVDG+T  + ++ SC H+ GE    WW V L  V  I RV I +R DCC  R   + + I  S EN  N + L +    I      P+G+        + V GR + I  P     +  CEV+V+
Sbjct:  187 GNAVDGSTESEYQEGSCSHTLGET-NPWWRVDLGRVFSIRRVSITNRGDCCEERLNGAEIRIGNSLENNGNSNHLVATVEHI------PAGN--TETFEFQPVQGRFLNIVLPGVNVYLTLCEVQVF 304

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BLAST of WSC domain-containing protein vs. Ensembl Zebrafish
Match: si:ch73-359m17.2 (si:ch73-359m17.2 [Source:ZFIN;Acc:ZDB-GENE-141222-90])

HSP 1 Score: 70.4774 bits (171), Expect = 1.403e-14
Identity = 42/126 (33.33%), Postives = 63/126 (50.00%), Query Frame = 2

Query:  128 NAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYN--RTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVY 499
            +AVDGNT  D ++ SC H+  E F  WW V L  VS + +V I +R DCC    R + + I  S EN  N + L++               K +     + + GR + +F P  +E ++ CEVEV+
Sbjct:   46 HAVDGNTEADYRKGSCTHTSRE-FNPWWRVDLGGVSSVNKVTITNRGDCCEERIRGAQIRIGDSLENNGNNNQLAATLLDA---------IKGSQTFEFQPIQGRYLNVFLPGNDETLSLCEVEVF 161

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BLAST of WSC domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-215k15.4 (si:ch211-215k15.4 [Source:ZFIN;Acc:ZDB-GENE-131127-215])

HSP 1 Score: 53.1434 bits (126), Expect = 3.919e-8
Identity = 45/163 (27.61%), Postives = 70/163 (42.94%), Query Frame = 2

Query:   20 SITALNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYP 508
            + TA    L    R T S  +     G+ +AS    NA+DGN + D    SC  ++ +  + WW + L D  V+  + I +R DCC  R     ++       N    + L  +I+     P+G  L      + + GR I +        +  CE+EVYGYP
Sbjct:   20 TTTAKARNLALSGRATQSDLLKNPWTGEALAS----NAIDGNRDPDFYHGSCTATEVQD-DPWWRLDLLDTYVVKSITITNRKDCCPERLDGAEVHIGNS-LLNNGNSNPLAAKISSI---PAGRSLTFK-WKKGISGRYINVILRGSNRILTLCELEVYGYP 172

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BLAST of WSC domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-215k15.4 (si:ch211-215k15.4 [Source:ZFIN;Acc:ZDB-GENE-131127-215])

HSP 1 Score: 52.7582 bits (125), Expect = 4.676e-8
Identity = 47/164 (28.66%), Postives = 71/164 (43.29%), Query Frame = 2

Query:   17 LSITALNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYP 508
            L I A N  L    R T S  +     G+ +AS    NA+DGN + D    SC  ++ +  + WW + L D  V+  + I +R DCC  R     ++       N    + L  +I+     P+G  L      + + GR I +        +  CE+EVYGYP
Sbjct:   16 LLIAARNLAL--SGRATQSDLLKNPWTGEALAS----NAIDGNRDPDFYHGSCTATEVQD-DPWWRLDLLDTYVVKSITITNRKDCCPERLDGAEVHIGNS-LLNNGNSNPLAAKISSI---PAGRSLTFK-WKKGISGRYINVILRGSNRILTLCELEVYGYP 167

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BLAST of WSC domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000031185.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV460386.1:115580:120446:1 gene:ENSXETG00000009779.1 transcript:ENSXETT00000031185.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.8474 bits (146), Expect = 3.601e-11
Identity = 38/127 (29.92%), Postives = 60/127 (47.24%), Query Frame = 2

Query:  128 NAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYP 508
            NA+DGN + + +  SC ++  EM   WW + L D   I++VV+ +R DCC +  +   I      E N +   S     +   G         A     +VGR + I  P +++ +  CEV+VYG P
Sbjct:   55 NAIDGNMDPNFQHGSCSYTNNEM-SPWWRLDLLDSYQISQVVVTNRGDCCGDLINGAQILVGDSMENNGNNNPSCAEIFSMQNGETQ------AFECNGMVGRFVNIILPGQQQYLTLCEVQVYGQP 174

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BLAST of WSC domain-containing protein vs. Ensembl Xenopus
Match: ncapg2 (non-SMC condensin II complex subunit G2 [Source:Xenbase;Acc:XB-GENE-1002744])

HSP 1 Score: 61.6178 bits (148), Expect = 6.597e-11
Identity = 43/148 (29.05%), Postives = 65/148 (43.92%), Query Frame = 2

Query:  125 SNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFST-LSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGY-------PYYRSNPSIYKLL 544
            SNA DG+ N D++  SC H+ G     WW + L     + +VVI +R DCC  R   L       N  N +  L      ++         +  + +   R+ GR + +  P +EE +  CEVEVYG        P  + + S+Y L 
Sbjct:  189 SNANDGDANTDMRYGSCSHT-GNDNPAWWQLDLKKRYKVDKVVIVNRGDCCGER--LLGAQVRVGNTANLNNPLCGTVTDVS---------EETITVSCHRMEGRYLTVVIPGREETLQLCEVEVYGQVFRAFIPPRDKGSDSLYTLF 324

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BLAST of WSC domain-containing protein vs. Ensembl Xenopus
Match: ncapg2 (non-SMC condensin II complex subunit G2 [Source:Xenbase;Acc:XB-GENE-1002744])

HSP 1 Score: 61.2326 bits (147), Expect = 1.078e-10
Identity = 43/148 (29.05%), Postives = 65/148 (43.92%), Query Frame = 2

Query:  125 SNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFST-LSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGY-------PYYRSNPSIYKLL 544
            SNA DG+ N D++  SC H+ G     WW + L     + +VVI +R DCC  R   L       N  N +  L      ++         +  + +   R+ GR + +  P +EE +  CEVEVYG        P  + + S+Y L 
Sbjct:  189 SNANDGDANTDMRYGSCSHT-GNDNPAWWQLDLKKRYKVDKVVIVNRGDCCGER--LLGAQVRVGNTANLNNPLCGTVTDVS---------EETITVSCHRMEGRYLTVVIPGREETLQLCEVEVYGQVFRAFIPPRDKGSDSLYTLF 324

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BLAST of WSC domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000031194.1 (fucolectin-4-like [Source:NCBI gene;Acc:100493719])

HSP 1 Score: 56.225 bits (134), Expect = 1.283e-9
Identity = 45/164 (27.44%), Postives = 75/164 (45.73%), Query Frame = 2

Query:   23 ITALNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYN--RTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYP 508
            ++++ + L  + R T SS  Y  + G      + +N+ DGN + +    SC  +  +M   WW V L     I++VV+ +R DCC      + + I  S EN  N +   +   +I +      G     A     +VGR + I  P ++  +  CEV+VYG P
Sbjct:    9 LSSIGQNLALRGRATQSSTYYNYNIG---YLALAANSNDGNLDSNYYHGSCSLTGNDM-SPWWRVDLLQPYKISQVVVTNRGDCCGEAINGALILIGDSLENNGNNNPSCA---EITYI-----GKGATQAFECNGMVGRFVTIVIPGRQTYLQMCEVQVYGEP 160

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BLAST of WSC domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000016029.1 (fucolectin-4-like [Source:NCBI gene;Acc:100493719])

HSP 1 Score: 56.225 bits (134), Expect = 1.303e-9
Identity = 43/164 (26.22%), Postives = 75/164 (45.73%), Query Frame = 2

Query:   23 ITALNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYN--RTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYP 508
            ++++ + L  + R T SS  Y  + G      + +N+ DGN + +    SC  +  E+   WW V L     I++VV+ +R DCC      + + I  S EN  N +   +  + +         +    A     +VGR + I  P +++ +  CEV+VYG P
Sbjct:   13 LSSIGQNLALRGRATQSSTYYNYNIG---YLALAANSNDGNLDSNYYHGSCSLTNSEL-SPWWRVDLLQPYKISQVVVTNRGDCCGEAINGALILIGDSLENNGNNNPSCAEIFSMQ--------NGETQAFECNGMVGRFVNIILPGQQQYLTLCEVQVYGQP 164

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BLAST of WSC domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9I925|FUCL7_ANGJA (Fucolectin-7 OS=Anguilla japonica OX=7937 PE=2 SV=1)

HSP 1 Score: 60.077 bits (144), Expect = 3.726e-10
Identity = 48/155 (30.97%), Postives = 72/155 (46.45%), Query Frame = 2

Query:   32 LNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEV 496
            + E +  + R T S+ + R D   GIA    SNA+DGN +      SC H++ +  + WW V L  V  IT V I +R DCC  R S   I      E N      +        GP +  +       + ++GR + ++ P K E+++ CEVEV
Sbjct:   39 IQENVALRGRATQSAQL-RGDH-SGIAHA--SNAIDGNRDSVFYHGSCTHTEAD--KPWWRVDLLQVYTITSVTITNRGDCCEERISGARILIGKHLENN-----GINNPQCSVIGPMAAGETKTFRCPQPMIGRYVTVYLP-KAESLHLCEVEV 181

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BLAST of WSC domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9I929|FUCL3_ANGJA (Fucolectin-3 OS=Anguilla japonica OX=7937 PE=2 SV=1)

HSP 1 Score: 59.6918 bits (143), Expect = 4.264e-10
Identity = 47/162 (29.01%), Postives = 73/162 (45.06%), Query Frame = 2

Query:   32 LNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETN------FSTLSSLFY-QINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEV 496
            + E +  + R T S+ +    +G+       SNA+DGN + +    SC H++G+    WW V L  V  IT V I +R DCC  R S   I      E N       ST++ +   +   F  P            + ++GR + ++ P K E++  CEVEV
Sbjct:   30 IQENVALRGRATQSAQL----KGEFAGFAHASNAIDGNRDSNYHHGSCSHTEGD--NSWWRVDLKQVYTITSVTITNRGDCCGERISGARILIGKHLENNGINNPECSTINIMAAGETKTFHCP------------QPMIGRYVTVYLP-KAESLQLCEVEV 172

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BLAST of WSC domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7SIC1|FUCL_ANGAN (Fucolectin OS=Anguilla anguilla OX=7936 PE=1 SV=1)

HSP 1 Score: 58.151 bits (139), Expect = 1.052e-9
Identity = 42/142 (29.58%), Postives = 62/142 (43.66%), Query Frame = 2

Query:   98 GDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETN---------FSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEV 496
            G+  A+   SNA+DGN + +    SC HS G+    WW V L  V  IT V I +R DCC  R S   I       +N           ++++   +    P P              ++GR +V + P   E+++ CEVEV
Sbjct:   25 GEHAANSEASNAIDGNRDSNFYHGSCTHSSGQA-NPWWRVDLLQVYTITSVTITNRGDCCGERISGAEINIGQHLASNGVNNPECSVIGSMATGETKTFHCPAP--------------MIGRYVVTYLPTS-ESLHLCEVEV 150

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BLAST of WSC domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9I928|FUCL4_ANGJA (Fucolectin-4 OS=Anguilla japonica OX=7937 PE=2 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 2.914e-9
Identity = 45/157 (28.66%), Postives = 66/157 (42.04%), Query Frame = 2

Query:   53 KNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETN---------FSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEV 496
            + R T S+ +     G+  A    SNA+DGN + +    SC H++G     WW V L  V  I  V I +R DCC  R S   I      E N           +L++   +    P P              ++GR + ++ P K E++  CEVEV
Sbjct:   37 RGRATQSAQL----RGEHAALAHASNAIDGNRDSNYHHGSCTHTEGA--NPWWRVDLLQVYTIASVTITNRGDCCGERISGARILIGNSLENNGINNPQCSVIGSLATGETRTFHCPQP--------------MIGRYVTVYLP-KIESLQLCEVEV 172

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BLAST of WSC domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9I931|FUCL1_ANGJA (Fucolectin-1 OS=Anguilla japonica OX=7937 PE=2 SV=1)

HSP 1 Score: 53.9138 bits (128), Expect = 5.773e-8
Identity = 42/140 (30.00%), Postives = 58/140 (41.43%), Query Frame = 2

Query:   98 GDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETN------FSTLSSL-FYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEV 496
            G G    +P  A+DGN + D    SC H+       WW V L  +  IT V I +R DCC  R S   I      E N       S + S+   +   F  P            + ++GR + ++ P K E +  CEVEV
Sbjct:   46 GAGAVLSLPGFAIDGNRDSDFSHGSCSHTTNSP-NPWWRVDLLQLYTITSVTITNRGDCCGERISGARILIGNSLENNGINNPACSVIGSMETGETRTFHCP------------QPMIGRYVTVYLP-KTEVLQLCEVEV 171

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BLAST of WSC domain-containing protein vs. TrEMBL
Match: A0A498MNV1 (Uncharacterized protein OS=Labeo rohita OX=84645 GN=ROHU_025076 PE=4 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 1.877e-13
Identity = 50/165 (30.30%), Postives = 77/165 (46.67%), Query Frame = 2

Query:   59 RITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIY--TSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYRSNPSIYKLLG 547
            + T S  V     G+G AS    NA+DGN +      SC H+  +  + WW + L D  V+T + I +R DCC  R     I+   S +N  N + L+     +      P+G  +    L + + GR + +  P     +  CEVEVYGYP +  +P  + +LG
Sbjct:  387 KATQSDLVGNPHSGEGHAS----NAIDGNLDSHFHHGSCTHTDSQN-DPWWRLDLLDEYVVTSITITNRKDCCPERLHGAEIHIGNSLQNNGNSNPLAGKISSV------PAGGSVTFD-LKKGIPGRYVNVVIPGSNRVLTLCEVEVYGYPAFYGSPGPFNMLG 539

HSP 2 Score: 67.0106 bits (162), Expect = 2.227e-9
Identity = 55/177 (31.07%), Postives = 79/177 (44.63%), Query Frame = 2

Query:    5 FLLFLSI--------TALNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRR-VVGRTIVIFKPIKEEAINFCEVEVYGYP 508
            FLL +S+        TA    L    + T S  V     G+G AS    NA+DGN +      SC H+  +  + WW + L D  V+T ++I +R DCC  R     I+       N    + L  +I+  P     D  +V   L++ + GR I +  P     +  CEVEVYGYP
Sbjct:    7 FLLCISVMPWFTDTTTAKARNLALYGKATQSDLVGDPWSGEGHAS----NAIDGNLDSHFHHGSCTHTDSQN-DPWWRLDLLDEYVVTSIIITNRKDCCPERLDGAEIHIGNS-LLNNGNSNPLAGKISSIP-----DGGSVTFDLKKGISGRYINVVIPGSNRVLTLCEVEVYGYP 172

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BLAST of WSC domain-containing protein vs. TrEMBL
Match: M4A8A0 (Si:ch211-215k15.4 OS=Xiphophorus maculatus OX=8083 PE=4 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 3.544e-13
Identity = 44/127 (34.65%), Postives = 70/127 (55.12%), Query Frame = 2

Query:  125 SNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGY 505
            SNA+DGN N D+ + SC H++ E    WW V L D  ++T+V+I +R DCC  R + + ++     + +  T + L   I+      +G   A+    + V GR ++I  P  + A++ CEVEVYGY
Sbjct:   48 SNAIDGNLNADLTKGSCTHTETEN-NPWWRVDLLDSYIVTQVIITNRGDCCAERLNGVEVHIGNSLQKDI-TANPLVATISAV---AAGSSYAIN-FTKHVEGRYVIIILPGAQRALHICEVEVYGY 168

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BLAST of WSC domain-containing protein vs. TrEMBL
Match: A0A3Q2ZQU6 (Si:ch211-215k15.4 OS=Kryptolebias marmoratus OX=37003 PE=4 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 5.495e-13
Identity = 46/136 (33.82%), Postives = 67/136 (49.26%), Query Frame = 2

Query:  128 NAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYRSNPSIY 535
            NA+DGN +   K  SC H++  +   WW V L D  +I  ++I +R DCC  R +   I+     E N  T +SL   I+  P   S           RV GR +V+ +P  ++ +  CEVEVYGY     N ++Y
Sbjct:   58 NAIDGNRDPVFKHGSCSHTETHV-NPWWRVDLLDSYIIDHIIITNRGDCCAERINGAQIHIGNSLEDN-GTRNSLVATISSIPAGGS----KTITFSSRVEGRFVVVLRPGADKLLTLCEVEVYGYLAPEENVAVY 187

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BLAST of WSC domain-containing protein vs. TrEMBL
Match: A0A3B3Z4X0 (FTP domain-containing protein OS=Poecilia mexicana OX=48701 PE=4 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 8.035e-13
Identity = 50/154 (32.47%), Postives = 73/154 (47.40%), Query Frame = 2

Query:   62 ITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETN------FSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGY 505
            +   S  Y+  E  G  +   SNA+DGN N   +  SC H++      WW V L D  V+T+V++ +R DCC  R +   I+     + N       +T+SS+          PSG    + I   RV GR + I  P  E+ +  CEVE+YGY
Sbjct:   29 LATQSQRYQGAEWGGFGA--ASNAIDGNRNSAFQDGSCSHTE-RQSNPWWRVDLLDSYVVTQVIVTNRGDCCEERINGAEIHIGNSLQGNGIENQLAATISSI----------PSGATQTINI-PNRVEGRYVTIVIPGSEKYLTLCEVEIYGY 168

[Close]

BLAST of WSC domain-containing protein vs. TrEMBL
Match: A0A3B5QXB1 (Uncharacterized protein OS=Xiphophorus maculatus OX=8083 PE=4 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 9.602e-13
Identity = 44/127 (34.65%), Postives = 69/127 (54.33%), Query Frame = 2

Query:  131 AVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNR--TSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGY 505
            A+DGN N ++K+ SC H+  E    WW V L D  ++T+V++ +R DCC  R   + + I  S +N    + L++    I      P+GD   + +   R+ GR + I  P  E+ ++ CEVEVYGY
Sbjct:   44 AIDGNQNSNLKKGSCTHTDTES-NPWWRVDLLDSYIVTQVIVTNRGDCCDERINGAEIRIGNSLQNNGVENPLAATISSI------PTGDSQVINVS-HRMEGRYVTIVIPGSEKTLSLCEVEVYGY 162

[Close]

BLAST of WSC domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000041629.1 (pep primary_assembly:Astyanax_mexicanus-2.0:2:30955763:30962150:-1 gene:ENSAMXG00000041548.1 transcript:ENSAMXT00000041629.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.3142 bits (155), Expect = 4.820e-12
Identity = 43/137 (31.39%), Postives = 66/137 (48.18%), Query Frame = 2

Query:  119 VPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRT--SFLSIYTSYENETNFSTLSSLFYQINFFPGPPSG--DKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYR 517
            +P NA+DGN N D+ + SC  ++ E    WW + L    VI+ V + +R DCC      + + I  S ENE   + L ++   I      P+G  +      LL    G  + +  P +E  ++ CEVEV+G P  R
Sbjct:  203 LPLNAIDGNRNSDLMKGSCMRTQQET-SPWWRLSLPRRYVISSVALTNRGDCCSEHVDGAEIRIGDSLENEGKDNPLCTIVSSI------PAGQTEHYNCTDLLE---GSYVTVVLPGEERTLSLCEVEVFGLPVAR 329

HSP 2 Score: 59.3066 bits (142), Expect = 2.890e-10
Identity = 40/128 (31.25%), Postives = 64/128 (50.00%), Query Frame = 2

Query:  125 SNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNR--TSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYG 502
            +NAVDGN+N +  + SC H+  +    W  V L DV  +T V I +R DCC +R   + + I  S +N+ N + L ++          P G ++      +   GR + IF P + + +  CEV+VY 
Sbjct:   43 ANAVDGNSNTNYLKKSCSHTHSDN-NPWLRVELPDVYNVTSVTIVNRKDCCGDRINGAQIRIGNSLDNKGNDNKLVAVI--------GPMGSEVIKTYKFKATEGRFVNIFLPGQRKILTLCEVKVYA 161

[Close]

BLAST of WSC domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000052178.1 (pep primary_assembly:Astyanax_mexicanus-2.0:2:30955763:30962678:-1 gene:ENSAMXG00000041548.1 transcript:ENSAMXT00000052178.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.3142 bits (155), Expect = 4.820e-12
Identity = 43/137 (31.39%), Postives = 66/137 (48.18%), Query Frame = 2

Query:  119 VPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRT--SFLSIYTSYENETNFSTLSSLFYQINFFPGPPSG--DKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYR 517
            +P NA+DGN N D+ + SC  ++ E    WW + L    VI+ V + +R DCC      + + I  S ENE   + L ++   I      P+G  +      LL    G  + +  P +E  ++ CEVEV+G P  R
Sbjct:  203 LPLNAIDGNRNSDLMKGSCMRTQQET-SPWWRLSLPRRYVISSVALTNRGDCCSEHVDGAEIRIGDSLENEGKDNPLCTIVSSI------PAGQTEHYNCTDLLE---GSYVTVVLPGEERTLSLCEVEVFGLPVAR 329

HSP 2 Score: 59.3066 bits (142), Expect = 2.890e-10
Identity = 40/128 (31.25%), Postives = 64/128 (50.00%), Query Frame = 2

Query:  125 SNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNR--TSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYG 502
            +NAVDGN+N +  + SC H+  +    W  V L DV  +T V I +R DCC +R   + + I  S +N+ N + L ++          P G ++      +   GR + IF P + + +  CEV+VY 
Sbjct:   43 ANAVDGNSNTNYLKKSCSHTHSDN-NPWLRVELPDVYNVTSVTIVNRKDCCGDRINGAQIRIGNSLDNKGNDNKLVAVI--------GPMGSEVIKTYKFKATEGRFVNIFLPGQRKILTLCEVKVYA 161

[Close]

BLAST of WSC domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000035078.1 (pep primary_assembly:Astyanax_mexicanus-2.0:2:30955763:30962150:-1 gene:ENSAMXG00000041548.1 transcript:ENSAMXT00000035078.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.3142 bits (155), Expect = 4.866e-12
Identity = 43/137 (31.39%), Postives = 66/137 (48.18%), Query Frame = 2

Query:  119 VPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRT--SFLSIYTSYENETNFSTLSSLFYQINFFPGPPSG--DKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYR 517
            +P NA+DGN N D+ + SC  ++ E    WW + L    VI+ V + +R DCC      + + I  S ENE   + L ++   I      P+G  +      LL    G  + +  P +E  ++ CEVEV+G P  R
Sbjct:  203 LPLNAIDGNRNSDLMKGSCMRTQQET-SPWWRLSLPRRYVISSVALTNRGDCCSEHVDGAEIRIGDSLENEGKDNPLCTIVSSI------PAGQTEHYNCTDLLE---GSYVTVVLPGEERTLSLCEVEVFGLPVAR 329

HSP 2 Score: 53.1434 bits (126), Expect = 3.405e-8
Identity = 44/162 (27.16%), Postives = 72/162 (44.44%), Query Frame = 2

Query:   23 ITALNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRT--SFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYG 502
            +TA  E +  ++R   SS      + +        +AVDGN + +  + SC H+  E  + W  V L  V  IT V I +R DCC  R   + + I  S +N  N + + ++          P G ++      +   GR + IF P + + +  CEV+VY 
Sbjct:   17 VTASKENIAVRSRAVQSSTYNELADAE--------HAVDGNIDSNYMRGSCTHTMPET-DPWLRVELPGVYKITSVTIFNRGDCCSERIHGAQVRIGNSLKNNGNENKIVAVI--------GPMGSEVIKTYKFKATEGRFVNIFLPGQRKILTLCEVKVYA 161

[Close]

BLAST of WSC domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000050908.1 (pep primary_assembly:Astyanax_mexicanus-2.0:2:30949256:30953032:-1 gene:ENSAMXG00000032389.1 transcript:ENSAMXT00000050908.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.929 bits (154), Expect = 5.750e-12
Identity = 40/128 (31.25%), Postives = 66/128 (51.56%), Query Frame = 2

Query:  122 PSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIY--TSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVY 499
            P  AVDGNT+ D ++ SC H+  E    WW V L  V  +T V I +R DCC +R     I+   S +N+ N + L ++          P+  ++ +    +   GR + IF P +++ ++ CEV+V+
Sbjct:  162 PEYAVDGNTDTDSRRGSCSHTLTEA-NPWWRVELPGVCNVTSVTIVNREDCCSDRIKGAQIHIGNSLKNKGNDNKLVAVI--------GPTLSEITMTYKFKATRGRFVNIFLPGEDKILSLCEVKVF 280

HSP 2 Score: 48.1358 bits (113), Expect = 1.385e-6
Identity = 32/90 (35.56%), Postives = 45/90 (50.00%), Query Frame = 2

Query:  128 NAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNR------TSFLSIYTSYENETNFSTLSSLFYQINFFPG 379
            NAVDGN+N +  + SC H+  E  + WW + L  V  IT V I +R DCC  R       +F  +  + +N++   T    F  I F PG
Sbjct:   40 NAVDGNSNANYWKGSCSHTSYET-DPWWRLELPAVYNITSVTIVNRGDCCGKRIIGAEIQAFTLLEKNQKNKSIRKTTEGQFVNI-FLPG 127

[Close]

BLAST of WSC domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000056118.1 (fucolectin-4-like [Source:NCBI gene;Acc:103037148])

HSP 1 Score: 61.6178 bits (148), Expect = 8.229e-12
Identity = 43/132 (32.58%), Postives = 60/132 (45.45%), Query Frame = 2

Query:  128 NAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFL------SIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGY 505
            NA+DGN N +    SC H+  +    WW V L     IT + I +R DCC NR +        S+Y +  + T  + +SS+       PG       +V   L  + GR I +  P     +  CEVEVYGY
Sbjct:   48 NAIDGNPNSNYHDGSCSHTSTQN-NPWWRVDLLYKYKITSITITNRGDCCANRINGAEIRVGNSLYNNGNSNTRVAVVSSIL------PGK------SVTFKLSNISGRYINVILPGYNRILTLCEVEVYGY 166

[Close]

BLAST of WSC domain-containing protein vs. Ensembl Nematostella
Match: EDO29994 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T225])

HSP 1 Score: 57.7658 bits (138), Expect = 2.498e-10
Identity = 40/131 (30.53%), Postives = 59/131 (45.04%), Query Frame = 2

Query:  119 VPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSF----LSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVY 499
            V S+AVDGN +G+    SC H+  E    WW V L     + +V I +R+DCC ++       + +  S  N  N +      Y I      P G  L +      + GR + I  P  ++ +  CEVEVY
Sbjct:  157 VASHAVDGNRDGNYGNWSCTHTNAET-NPWWRVDLGASHRVAQVFIVARSDCCGDKQELRNIVIHVGDSLANNGNTNARCGGAYTI------PQGKNLTI-TCSPALQGRYVSIMLPGAKQILTLCEVEVY 279

[Close]

BLAST of WSC domain-containing protein vs. Ensembl Nematostella
Match: EDO34462 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPB1])

HSP 1 Score: 55.0694 bits (131), Expect = 4.032e-10
Identity = 44/129 (34.11%), Postives = 57/129 (44.19%), Query Frame = 2

Query:  119 VPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIY--TSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVY 499
            +  +AVDGN NG     SC  +K +    WW V L    VI R+ I +R DCC +R     I    S EN  N +      Y I      P    +A   LL+   GR + I+ P     +  CEVEVY
Sbjct:   10 LAEHAVDGNRNGRYFDLSCTETKVQS-NPWWRVDLQKSYVILRLFIVNRADCCNHRLDNFEIRIGDSLENNGNDNPTCGGSYII------PKNGSIACHTLLK---GRYVNIWIPGPNRLLTLCEVEVY 128

[Close]

BLAST of WSC domain-containing protein vs. Ensembl Nematostella
Match: EDO40750 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6H5])

HSP 1 Score: 55.4546 bits (132), Expect = 4.707e-10
Identity = 48/149 (32.21%), Postives = 73/149 (48.99%), Query Frame = 2

Query:   65 TNSSNVYRTD-EGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTS--FLSIYTSYENETNFSTLSSLFYQINFFPGPPS-GDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVY 499
            T  S+ YR+D +GDG+++    +AVDGN +G+  Q SC  +  +    WW V L    V  R+ + +R DCC  R     + I  S  N+ N +      Y I     P   G+ +A   LL+   GR + I+    ++ +  CEVEVY
Sbjct:    8 TVQSSTYRSDSKGDGLSN----HAVDGNRSGNYYQKSCSSTTAQT-NPWWRVDLQKSHVNLRLFVVNRADCCGERLDNFEIRIGDSLVNDGNDNPSCGSSYII-----PQGRGNTIACHTLLK---GRYVNIWIQGPDKVLTLCEVEVY 143

[Close]

BLAST of WSC domain-containing protein vs. Ensembl Nematostella
Match: EDO25871 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TDH1])

HSP 1 Score: 49.6766 bits (117), Expect = 3.217e-8
Identity = 42/132 (31.82%), Postives = 60/132 (45.45%), Query Frame = 2

Query:  119 VPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTS--FLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDK-LAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGY 505
            +  +AVDG+ +G     SC  +K +    WW V L    VI R+ I +R DCC  R     + I  S EN    +      Y I     P  G K ++   LL+   GR + I+ P  +  +  CEVEVY +
Sbjct:    2 LAEHAVDGDRSGRFADLSCTETKVQS-NPWWRVDLQKSYVILRLFIVNRADCCGERLDNFEIRIGDSLENNGTDNPSCGSSYII-----PHGGSKSISCHTLLK---GRYVNIWIPGSDRRLTLCEVEVYPF 124

[Close]

BLAST of WSC domain-containing protein vs. Ensembl Nematostella
Match: EDO33194 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSX9])

HSP 1 Score: 48.1358 bits (113), Expect = 9.860e-8
Identity = 42/126 (33.33%), Postives = 57/126 (45.24%), Query Frame = 2

Query:  128 NAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTS--FLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDK-LAVAILLRRVVGRTIVIFKPIKEEAINFCEVEV 496
            +AVDGN +G     SC  +K +    WW V L    VI R+ I +R DCC  R     + I  S EN    +      Y I     P  G K ++   LL+   GR + I+ P  +  +  CEVEV
Sbjct:    3 HAVDGNRSGRFSDLSCTETKVQS-NPWWRVDLQKSYVILRLFIVNRADCCGERLDNFEIRIGDSLENNGTDNPSCGSSYII-----PHGGSKSISCHTLLK---GRYVNIWIPGSDRRLTLCEVEV 119

[Close]

BLAST of WSC domain-containing protein vs. Planmine SMEST
Match: SMESG000024496.1 (SMESG000024496.1)

HSP 1 Score: 390.193 bits (1001), Expect = 1.124e-139
Identity = 188/189 (99.47%), Postives = 188/189 (99.47%), Query Frame = 2

Query:   38 EILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYRSNPSIYKLLGTYPLYSNIPAIQYRTCRSS 604
            EILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFST SSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYRSNPSIYKLLGTYPLYSNIPAIQYRTCRSS
Sbjct:   18 EILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTFSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYRSNPSIYKLLGTYPLYSNIPAIQYRTCRSS 206

[Close]

BLAST of WSC domain-containing protein vs. Planmine SMEST
Match: SMESG000024886.1 (SMESG000024886.1)

HSP 1 Score: 154.451 bits (389), Expect = 1.486e-46
Identity = 75/184 (40.76%), Postives = 117/184 (63.59%), Query Frame = 2

Query:   20 SITALNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYRSNPSIYKLLGTYPLYSNI 571
            S++ + +++LS+ R T  + +       G +   P  AVDGN +G+    SC+HS+G    KWWLV LD +SV+T+VVI+SRTDCC NRTSF+S Y SY+N T+ +   + F+ I+++ GPP   ++   +  +R+  RT+ I KP+  + IN CE+EVYGYP  +S  +++K  GT  LY ++
Sbjct:   34 SLSFVLDLILSRGRPTFGTII------AGYSVWEPQKAVDGNYDGNQFNGSCFHSEGPNVNKWWLVILDSLSVVTKVVIYSRTDCCTNRTSFISFYVSYKNSTSLTNNMNDFFNISYYAGPPPPGEIITTLNFKRLYARTLAISKPLAADHINLCELEVYGYPLIKSMFTLFKYFGTLSLYDSL 211

[Close]

BLAST of WSC domain-containing protein vs. Planmine SMEST
Match: SMESG000046841.1 (SMESG000046841.1)

HSP 1 Score: 153.295 bits (386), Expect = 2.030e-46
Identity = 84/202 (41.58%), Postives = 115/202 (56.93%), Query Frame = 2

Query:    5 FLLFL-SITALNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYRSNPSIYKLL------------GTYPLYSNI 571
            FLLF+  IT     LLS+ R T ++NV      D         AVDGN +G++    CYHSK     KWWL+ LD +SV+TRVVI+SRT+CC  RTS LS Y SY N T+ ST S+ F  ++++PG P   +    +   R+  RT+ I KP  E+  N CE+EVYGYP+ ++ P  +K L            GT+P+ SN+
Sbjct:   11 FLLFVFQITTAQNALLSRGRPTFAANVI-----DNQPYWSSDKAVDGNYDGNMVDGHCYHSKELNSTKWWLIILDSLSVVTRVVIYSRTECCTQRTSLLSFYVSYTNSTSLSTNSNDFTNVSYYPGSPPPGEFITTLNFTRLYARTLAISKPFAEQPFNLCELEVYGYPFIKTMPMTFKYLRALSIYDSLGNIGTFPVLSNL 207

[Close]

BLAST of WSC domain-containing protein vs. Planmine SMEST
Match: SMESG000024945.1 (SMESG000024945.1)

HSP 1 Score: 142.124 bits (357), Expect = 8.363e-42
Identity = 73/195 (37.44%), Postives = 120/195 (61.54%), Query Frame = 2

Query:   20 SITALNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYRSNPSIYKLLGTYPLYSNIPAIQYRTCRSS 604
            S++ + +++LS+ R T  + +       G +   P  AVDGN +G+    SC+HS+G    KWWLV LD +SV+T+VVI+SRTDCC +RTS +S Y SY N T+ +   + F+ I+++ GPP   ++   +  +R+V +T+ I KP+  + I+ CE++VYGYP  +S  +++K  GT  LY ++  +   T  S+
Sbjct:   34 SLSFVLDLILSRGRPTFGTII------AGYSVWGPQKAVDGNYDGNHFDGSCFHSEGPNVNKWWLVILDSLSVVTKVVIYSRTDCCTSRTSLISFYVSYINSTSLTNNMNDFFNISYYAGPPPPGEIITTLNFKRLV-KTLAISKPLAADPISLCELDVYGYPLIKSTFTLFKYFGTLSLYDSLGNVGIFTVVSN 221

[Close]

BLAST of WSC domain-containing protein vs. Planmine SMEST
Match: SMESG000024705.1 (SMESG000024705.1)

HSP 1 Score: 141.354 bits (355), Expect = 1.012e-41
Identity = 75/191 (39.27%), Postives = 114/191 (59.69%), Query Frame = 2

Query:    8 LLFLSITALNEILLSKNRITNSSNVYRTDEGDGIASMVP---SNAVDGNTNGDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLSIYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIFKPIKEEAINFCEVEVYGYPYYRSNPSIYKLLGTYPLYSNI 571
            ++ + I    + LLS  R T ++N           +M P     AVDGN NG++ + SCYHS+   ++KWWLV LD +SV+T+VVI+SRTDCC  RTS LS Y SY++ T+ S  ++ F  ++++ GPP   +    +   R+  RT+ I KP  E+AIN CE+EVYGYP+ ++    +K  G   +Y ++
Sbjct:   13 VIIVEIIVAEDSLLSIGRPTFANN-----------AMFPWTSDKAVDGNYNGNMSKGSCYHSETFNYDKWWLVILDSLSVVTKVVIYSRTDCCTQRTSLLSFYVSYKSSTSLSNNNNDFVNVSYYAGPPPPGEFITTLNFTRLYARTLAISKPSLEDAINLCELEVYGYPFTKTMSMTFKYFGALSIYDSL 192

The following BLAST results are available for this feature:

BLAST of WSC domain-containing protein vs. Ensembl Human
BLAST of WSC domain-containing protein vs. Ensembl Celegans
BLAST of WSC domain-containing protein vs. Ensembl Fly
BLAST of WSC domain-containing protein vs. Ensembl Zebrafish
BLAST of WSC domain-containing protein vs. Ensembl Xenopus
BLAST of WSC domain-containing protein vs. Ensembl Mouse
BLAST of WSC domain-containing protein vs. UniProt/SwissProt
BLAST of WSC domain-containing protein vs. TrEMBL
BLAST of WSC domain-containing protein vs. Ensembl Cavefish
BLAST of WSC domain-containing protein vs. Ensembl Sea Lamprey
BLAST of WSC domain-containing protein vs. Ensembl Yeast
BLAST of WSC domain-containing protein vs. Ensembl Nematostella
BLAST of WSC domain-containing protein vs. Ensembl Medaka
BLAST of WSC domain-containing protein vs. Planmine SMEST

BLAST of WSC domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of WSC domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of WSC domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of WSC domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:ch73-359m17.2	4.856e-15	33.33	si:ch73-359m17.2 [Source:ZFIN;Acc:ZDB-GENE-141222-...	[more]
si:ch73-359m17.2	9.863e-15	33.33	si:ch73-359m17.2 [Source:ZFIN;Acc:ZDB-GENE-141222-...	[more]
si:ch73-359m17.2	1.403e-14	33.33	si:ch73-359m17.2 [Source:ZFIN;Acc:ZDB-GENE-141222-...	[more]
si:ch211-215k15.4	3.919e-8	27.61	si:ch211-215k15.4 [Source:ZFIN;Acc:ZDB-GENE-131127...	[more]
si:ch211-215k15.4	4.676e-8	28.66	si:ch211-215k15.4 [Source:ZFIN;Acc:ZDB-GENE-131127...	[more]

BLAST of WSC domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSXETT00000031185.1	3.601e-11	29.92	pep primary_assembly:Xenopus_tropicalis_v9.1:KV460...	[more]
ncapg2	6.597e-11	29.05	non-SMC condensin II complex subunit G2 [Source:Xe...	[more]
ncapg2	1.078e-10	29.05	non-SMC condensin II complex subunit G2 [Source:Xe...	[more]
ENSXETT00000031194.1	1.283e-9	27.44	fucolectin-4-like [Source:NCBI gene;Acc:100493719]	[more]
ENSXETT00000016029.1	1.303e-9	26.22	fucolectin-4-like [Source:NCBI gene;Acc:100493719]	[more]

BLAST of WSC domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of WSC domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9I925\|FUCL7_ANGJA	3.726e-10	30.97	Fucolectin-7 OS=Anguilla japonica OX=7937 PE=2 SV=...	[more]
sp\|Q9I929\|FUCL3_ANGJA	4.264e-10	29.01	Fucolectin-3 OS=Anguilla japonica OX=7937 PE=2 SV=...	[more]
sp\|Q7SIC1\|FUCL_ANGAN	1.052e-9	29.58	Fucolectin OS=Anguilla anguilla OX=7936 PE=1 SV=1	[more]
sp\|Q9I928\|FUCL4_ANGJA	2.914e-9	28.66	Fucolectin-4 OS=Anguilla japonica OX=7937 PE=2 SV=...	[more]
sp\|Q9I931\|FUCL1_ANGJA	5.773e-8	30.00	Fucolectin-1 OS=Anguilla japonica OX=7937 PE=2 SV=...	[more]

BLAST of WSC domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A498MNV1	1.877e-13	30.30	Uncharacterized protein OS=Labeo rohita OX=84645 G...	[more]
M4A8A0	3.544e-13	34.65	Si:ch211-215k15.4 OS=Xiphophorus maculatus OX=8083...	[more]
A0A3Q2ZQU6	5.495e-13	33.82	Si:ch211-215k15.4 OS=Kryptolebias marmoratus OX=37...	[more]
A0A3B3Z4X0	8.035e-13	32.47	FTP domain-containing protein OS=Poecilia mexicana...	[more]
A0A3B5QXB1	9.602e-13	34.65	Uncharacterized protein OS=Xiphophorus maculatus O...	[more]

BLAST of WSC domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000041629.1	4.820e-12	31.39	pep primary_assembly:Astyanax_mexicanus-2.0:2:3095...	[more]
ENSAMXT00000052178.1	4.820e-12	31.39	pep primary_assembly:Astyanax_mexicanus-2.0:2:3095...	[more]
ENSAMXT00000035078.1	4.866e-12	31.39	pep primary_assembly:Astyanax_mexicanus-2.0:2:3095...	[more]
ENSAMXT00000050908.1	5.750e-12	31.25	pep primary_assembly:Astyanax_mexicanus-2.0:2:3094...	[more]
ENSAMXT00000056118.1	8.229e-12	32.58	fucolectin-4-like [Source:NCBI gene;Acc:103037148]	[more]

BLAST of WSC domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of WSC domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of WSC domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO29994	2.498e-10	30.53	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34462	4.032e-10	34.11	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40750	4.707e-10	32.21	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO25871	3.217e-8	31.82	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33194	9.860e-8	33.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of WSC domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of WSC domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000024496.1	1.124e-139	99.47	SMESG000024496.1	[more]
SMESG000024886.1	1.486e-46	40.76	SMESG000024886.1	[more]
SMESG000046841.1	2.030e-46	41.58	SMESG000046841.1	[more]
SMESG000024945.1	8.363e-42	37.44	SMESG000024945.1	[more]
SMESG000024705.1	1.012e-41	39.27	SMESG000024705.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30003737 ID=SMED30003737|Name=WSC domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=605bp
CTCTTTTCTTTTGTTTTTAAGTATCACCGCGCTTAATGAAATTCTTCTCT
CCAAAAACCGAATTACAAATTCGTCAAATGTTTACAGAACTGACGAGGGT
GACGGAATAGCTTCGATGGTACCTTCGAATGCAGTAGACGGGAATACGAA
TGGGGACATAAAACAAAATTCCTGCTACCATAGCAAAGGCGAAATGTTTG
AGAAATGGTGGCTTGTCTGTCTTGATGATGTCAGTGTTATCACAAGGGTG
GTCATTCATAGCCGAACCGATTGTTGCTACAACCGAACAAGCTTTTTGTC
AATTTATACTAGCTATGAAAATGAAACCAATTTCTCAACACTTTCATCGT
TATTTTATCAAATAAATTTCTTTCCAGGACCTCCTTCCGGAGACAAATTG
GCCGTTGCAATACTACTGAGACGAGTGGTCGGGAGGACTATTGTCATATT
CAAACCAATCAAAGAGGAAGCTATTAACTTTTGTGAGGTAGAGGTTTACG
GGTATCCTTATTATAGAAGTAACCCATCAATTTATAAATTGTTGGGAACG
TATCCTCTCTACTCGAACATTCCAGCTATTCAATATCGAACATGCAGATC
AAGCG

protein sequence of SMED30003737-orf-1

>SMED30003737-orf-1 ID=SMED30003737-orf-1|Name=SMED30003737-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=201bp
SFLLFLSITALNEILLSKNRITNSSNVYRTDEGDGIASMVPSNAVDGNTN
GDIKQNSCYHSKGEMFEKWWLVCLDDVSVITRVVIHSRTDCCYNRTSFLS
IYTSYENETNFSTLSSLFYQINFFPGPPSGDKLAVAILLRRVVGRTIVIF
KPIKEEAINFCEVEVYGYPYYRSNPSIYKLLGTYPLYSNIPAIQYRTCRS
S

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **INTERPRO**
Term	Definition
IPR008979	Galactose-bd-like_sf
IPR000421	FA58C

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000421	Coagulation factor 5/8 C-terminal domain	PFAM	PF00754	F5_F8_type_C	coord: 21..134 e-value: 3.8E-7 score: 30.3
IPR008979	Galactose-binding-like domain superfamily	GENE3D	G3DSA:2.60.120.260		coord: 14..168 e-value: 1.2E-25 score: 92.1
IPR008979	Galactose-binding-like domain superfamily	SUPERFAMILY	SSF49785	Galactose-binding domain-like	coord: 16..170
None	No IPR available	PANTHER	PTHR45713	FAMILY NOT NAMED	coord: 13..96
None	No IPR available	PANTHER	PTHR45713:SF6	SI:CABZ01040626.2-RELATED	coord: 13..96

Main menu

WSC domain-containing protein

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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