Cytochrome P450 2K1-like protein

Query:  152 FFLLILISVVALLFNF----LRPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFT-LPILDRFPRICDFLMSFTTRKDLFNK--IHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVF 1648
            F +L+L     LLF+      R R +P G   +PI        +L +    I + +    K +GPVF +  G+  I V + Y+A++ ALIDN + FSGR     S   T+  GI+S++G +    RRF +  +  FGMG       +Q E   L+E L K K      + I+     N+I   +  K F   D      +N LT + R  + F+ L    + + + FP + D     T  K L N       ++++++EH+ + DV N   D ID FL+K +Q K +++S   F    LV  + +LF+AG ETTST   + L  + K+ E+ AKV +EI   IG  R P   DR  + YT AV+ EI R S ++P  + H  T DT+  +Y IPK + ++  L +   D   +  P  F P HFL   +NGN K    D   PF  GKR C GE L RM+ F+F  +ILQ F +   D +            +GIV  P   +  F
Sbjct:    4 FVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPI-----IGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKD------QNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPG-THNKVLKNVALTRSYIREKVKEHQASLDVNNP-RDFIDCFLIKMEQEKDNQKS--EFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLD--KNGNFKK--SDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKN---LNTTAVTKGIVSLPPSYQICF 487          

Query:  143 MIWFFLLILISV---VALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFP-ILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPIL---DRFPRICDFLMSFTTRKDLFN--KIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVS-FADP 1567
            ++W   L+L+S+   V   +N L P P P            P +G L  L    I + + RL ++ GPVF + +G + + V++ Y+A++ AL+D KD FSGR  L  +    R+ GI+  +G      RRF +  +  +GMG   + + IQ E   LLE L K +G+    + +I     N+I   L  K F   D K   +  +  E         F   + P L   + FP    +L   + RK + N  ++   + + ++EH ++ D  N   DL D  L++ ++ K S E + +     +   + +LF AG ETTST   + L  + KY EI+ K+H+EI   IG  R+P   DR+++ Y  AV+ EI R  +++P  L H  T DT    Y IPK ++V+  L +   D   +  P +F PEHFL+  ENG  KY   D   PF  GKR C GE L RM+ F+   +ILQ F +    DP
Sbjct:   11 LVWAAFLLLVSMWRQVHSSWN-LPPGPFP-----------LPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDL-PAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNE--------NFHLLSTPWLQLYNNFPSFLHYLPG-SHRKVIKNVAEVKEYVSERVKEHHQSLD-PNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVT--VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLN--ENGKFKY--SDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDP 466          

Query:  143 MIWFFLLILISV---VALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFP-ILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPIL---DRFPRICDFLMSFTTRKDLFN--KIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVS-FADP 1567
            ++W   L+L+S+   V   +N L P P P            P +G L  L    I + + RL ++ GPVF + +G + + V++ Y+A++ AL+D KD FSGR  L  +    R+ GI+  +G      RRF +  +  +GMG   + + IQ E   LLE L K +G+    + +I     N+I   L  K F   D K   +  +  E         F   + P L   + FP    +L   + RK + N  ++   + + ++EH ++ D  N   DL D  L++ ++ K S E + +     +   + +LF AG ETTST   + L  + KY EI+ K+H+EI   IG  R+P   DR+++ Y  AV+ EI R  +++P  L H  T DT    Y IPK ++V+  L +   D   +  P +F PEHFL+  ENG  KY   D   PF  GKR C GE L RM+ F+   +ILQ F +    DP
Sbjct:   11 LVWAAFLLLVSMWRQVHSSWN-LPPGPFP-----------LPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDL-PAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNE--------NFHLLSTPWLQLYNNFPSFLHYLPG-SHRKVIKNVAEVKEYVSERVKEHHQSLD-PNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVT--VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLN--ENGKFKY--SDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDP 466          

Query:  293 ILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPK----LNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSF-TTRKDLFNKIHRI---LQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVT 1573
            +L+ + R  +K+G VF + +G R + +L   +AIR AL+D  + FSGR ++       R  G++  +G++  + RRF +  M +FGMG       IQ E   L+E L K KG  +  + +  +  ANII   +  K F   D +    LNL     + I+    +F  L         F     FL  F    + ++  +  I   +   +E+HR+T D  +  +DLID +L+  ++ KS+  S  S  +  L  + L LF AG ETTST   +    M KY  +  +V++EI   IG  R P  +DR  + YT AV+ EI R S +LP+ + H  T  T    Y IPKD+ V + L     DP+ +EKP  F P+HFL    NG +K    +   PF +GKR C+GE + R + F+FF +ILQ F  S A PV 
Sbjct:   51 LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLIS---SVFGQL---------FELFSGFLKYFPGAHRQVYKNLQEINAYIGHSVEKHRETLD-PSAPKDLIDTYLLHMEKEKSNAHSEFSHQNLNL--NTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLD--ANGALKKT--EAFIPFSLGKRICLGEGIARAELFLFFTTILQNF--SMASPVA 464          

Query:  239 PIEKGFPFVG-ILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPK-LNLIKNILTEIA-RTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV-SFADP 1567
            P     P +G IL +    I +    L K +GPVF +  GL+ I VL+ Y+A++ ALID  + FSGR     +    R  GIV ++G +    RRF +  +  FGMG       +Q E   L+E L K K      + I+     N+I   + +K F   D + LNL++ +   I   +    Q      PI+D FP   + L+    +   F K +  + ++++EH+++ D+ N  +D ID FLMK ++ K ++ S   FT   L    ++LF AG ETTST   ++L  + K+ E+ AKV +EI   IG  R P   DR  + YT AV+ E+ R   +LP +L H  T D +  +Y IPK + +LI+L +   D   +  P  F P HFL   E GN K        PF  GKR C+GE+L  M+ F+F  SILQ F + S  DP
Sbjct:   31 PGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLL----KNVAFMKSY--ILEKVKEHQESMDMNNP-QDFIDCFLMKMEKEKHNQPS--EFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLD--EGGNFKK--SKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDP 464          

Query:  320 KKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLF--QSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKC---KGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFL---YFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFD---VKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVT 1573
            +++G +F + +G   + +++D   I+   I + D+FS RWR F   S++   N GIV  DG++    RRF +  + +FG+G       I  E T+L+  +EK     G+ + +   I   + NII   L    F+  +  ++ +  +L + + T  + Q +   Y   P+  + P I      +     + N++   L+ +IE HR  +    ++ E EDL   ++++ ++ K + E V  F D QL   LL+LF AG ETT T   W+   M+K Q++Q  V  E LDSIG   +   + R  L Y  A ++EI R++++LP+ L+     D E++ Y   K  L++  +     DP ++E P EF P  FL   E+ N+K +  D+  PF +G+RQC+GESL R + ++ F +++Q F    AD VT
Sbjct:   87 QQYGGIFTVWIGPIPLVMVSDLPTIKKYFIQHADSFSNRWRNFVTDSIMEGSN-GIVQIDGNKWREQRRFALHTLRDFGVGKPLMEQMITLEVTSLMNHMEKSCGLDGKELHLCPSIAVCVGNIINNMLFGLRFNQDNSYMHRLHQLLDDQSHT--VMQPIMGAYIAFPVTSKIPIING---EWNRLMGIKNELLEFLETQIEGHRMNWKDEMIEQEPEDLTYAYMIEVEKRKRNGEDVGFFDDQQLKMLLLDLFFAGMETTVTTLKWAFLLMAKNQKVQKNVQAE-LDSIGQPMIEIQH-RTRLPYVQATINEIQRIANILPINLLRTVAEDIEIDGYNFKKGDLIIPQISILMNDPEIFENPEEFNPSRFLD--EDNNVKKI--DEFLPFSIGRRQCLGESLARAELYLVFANLIQNFNFEVADDVT 503          

Query:  182 ALLFNFL--RPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEY--YERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRL-FQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQ----EIEEHRKTFDVK-NEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV 1552
            A LF+ L  + R  P G   +P+      +G L  L  P   Y  + R   K+G ++   +G R   +++ Y+A++   I + + ++ +  + FQ      + G+V T+G     HRRF I    +FG+G  R    I  E   +    +K  GE + ++DI    + N+I + L    F   + + +  + I           +F  F++ +    P +  ++M   T  D F K  +   +    +IE H+K  D +  E  D ++ FL +Q + ++S +  +SF+  QL    L+L+ A   TTS    W   +   Y + Q K+H+E+   IG+ER     D+ +L YT A ++EI R ++++PL L+H TT DT +  Y IPK + V+  +     D NV+ +P  F PE FL   ++G +K V  +QL PF +GKRQC+GE L RM+ F+F  +   R++V
Sbjct:   12 AFLFHHLYWKRRNWPAGPTPLPL------IGNLLSLRNPAPGYKAFARWTAKYGDIYTFWLGTRPYILVSSYEALKETFIKDGETYADKKPMAFQESFRGGSYGVVETNGPFWREHRRFAIHQFRDFGLGKDRMEQRIMLEVEDIFNNCDKTIGEGVDLTDIFDRAVGNVINQMLFGYRFD--ETRADEFRTIRAFFNFNSG--EFASFSMRVQFFLPWMG-YIMPGPTILDRFKKYQKGFTEFFGTQIENHKKEIDFELEENSDYVEAFLKEQRKREASGD-FESFSTKQLSNMCLDLWFAALMTTSNTMTWCFAYTLNYLDAQQKLHEELDRVIGSERHINTADKPNLPYTNAYINEIQRTANLVPLNLLHMTTRDTVLKGYNIPKGTGVVAQISTVMYDENVFPEPYIFKPERFLD--DDGKLKKV--EQLVPFSVGKRQCLGEGLARMELFLFIANFFNRYRV 462          

Query:  152 FFLLILISVVALLFNF-LRPRPIPKGLQKVPIEKGFPFVGILPLLTFP---ILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRW-RLFQSLLGTRN-AGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGER-IQVSDIIPTYMANIITKFLMNKTFSVGDPKL--NLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQ 1549
            F L  +I ++  +F+F  +    PKG   +P+    PF+G   +  FP   + +Y++ L K +GP F + +    I VL DY+ I++A ++  D F+ R  R  ++LL   +  GI+++DGD   + RR  ++++ +FG+G       +      +L  LE    ++ + V   I   + N+I + L    +   D +     +K +   +   +     L    P L   P + D  + +   K+  +  H  +++E+    K +D ++E E+ +  ++ +  Q  +    + +     L   +L+ +LAG ETTS    W L FM KY E+Q KV +EILD++GT RLP+ +D+ ++ YT AV+ E+ R S+++P    H+   +TE++   +P  SLV   L++   +  V+E P  F P  +L        K V +  + PF +GKR C+GE L RM+ F+ F +++Q+++
Sbjct:    4 FILAFVIFIIFYVFHFYWKVSKYPKG--PLPL----PFIG--NIHQFPPDNVQKYFDVLSKTYGPCFTIWIPFPAI-VLTDYEHIKDAFVNQGDTFTYRAHRSPETLLPVHDHTGILASDGDHWRLQRRTSLKILRDFGLGRNLMEEQVIRSVHEMLIQLENINDKKNVDVFWPIQLCVGNVINETLFGFHYKYEDSEKFKTFVKIVDKHLRHLQGKMPLLVSAFPWLKHVPIVGD--IGYHNIKNNISSYHTFIEEEVATQVKKYDGESEPENFVHAYMQQMKQTGNPGLDITN-----LCATVLDFWLAGMETTSNSLRWHLAFMMKYPEVQDKVRKEILDNVGTARLPSMSDKPNMPYTQAVIHEVQRCSNMIPFLGSHQCKEETEIHGNRVPAGSLVFAQLWSVMRNDTVFEDPETFNPSRYLQSDGKTFDKAVLEKTI-PFSIGKRNCVGEGLARMELFLIFSALIQKYE 461          

Query:  143 MIWFFLLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRL-FQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQ----FLYFTLPILDRFPRICDFLMSFTTRKD----LFNKIHRILQQEIEEHRKTF-DVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV 1552
            MI   LL  +++  +   + + R  P G   +P+      +   P    P  + +ER  KK+G V+   +G     ++N +  I+   I + D ++ +  L   +L      GI+ ++G     HRRF +  M +FG+G      NI  E   +   L+   G    V ++    +AN++ + L    F    PK N  + +   I    +IF     FL   +PI  +      +     T +D     FNK     Q E   HR  F D+ +E  D ++ FL K+ + + SE   +++++ QL+   ++L+ AG  TT+    W++ ++  + E+Q K+H+E+   IG++RL T  D+ DL Y  A ++E  R  ++LPL L H TT DT ++ + IPK + V+  +     +  V+  P  F P+ F+   ENG +K V  D+L PF +GKR C GE L RM+ F+F  + L R+++
Sbjct:    1 MIIILLLTFLTIYFVYELYWKRRNFPPGPCPLPVFGNLLSIANPP----PGYKAFERWTKKYGDVYTFWIGNTPHIMINTWDKIKETFIRDADTYTNKVVLPMVTLSRGGEYGIIDSNGAMWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDVPEVFDHAVANVVNQLLFGYRFM--GPKENEYQELKHIIDSPAEIFGKLHIFLAMNIPIFAKLLPESLYEGPIKTFRDTTLAFFNK-----QIEAHRHRIDFEDLNSESTDFVETFL-KEQKRRESEGDSETYSNIQLLNVCIDLWFAGLNTTTNTITWAISYVLHHPEVQDKIHEELDKVIGSDRLITTADKNDLPYFNASINESQRGINILPLNLQHATTRDTVIDGFKIPKGTGVVAQISTVMNNEEVFPDPYTFNPDRFID--ENGKLKKV--DELAPFSVGKRSCPGEGLARMELFLFIANFLNRYKI 464          

Query:  290 PILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQ-SLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIF----QFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKN---EGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV 1552
            P  E +ER  KK+G ++   +G     ++N +  I+   I + + ++ + RL    L      GI+ ++G     HRRF +  M +FG+G      NI  E   +   L+   G    + ++    +AN++ + L    F VG PK +  + +   I    D+F     FL   +P++    ++    M     KD  +       ++IE HR+  D+ +   E  D ++ FL K+ + + SE   ++F++ QL    ++L+ AG  TT+    W++ ++  + E+Q KVH+E+   IG++RL T  D+ DL Y  A ++E  R  +++PL L H TT DT +N + IPK + V+  +     +  V+  P  F P+ F+   E+G +K V  ++L PF +GKR C GE L RM+ F+F  + L R+++
Sbjct:   46 PGYEAFERWTKKYGDIYTFWIGNTPHIMINTWDKIKETYIRDAETYTNKVRLPALDLFRGGEYGIIDSNGATWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDIPEVFDHAVANVVNQLLFGYRF-VG-PKESEYQELKRIIEAPTDLFGKPHMFLAMNIPVI---AKLMPEFMYEGPFKDFRDTAFAFFNKQIEAHRQEVDLNDLNSESTDFVETFL-KEQKRRESEGDSETFSNVQLSNVCMDLWFAGLNTTTNTITWAISYILHHPEVQDKVHEEMDKVIGSDRLITTADKNDLPYFNAFINEAQRGINIVPLNLQHATTRDTVINGFKIPKGTGVVAQISTVMNNEEVFPDPHTFNPDRFID--EHGKLKRV--EELAPFSVGKRSCPGEGLARMELFLFIANFLNRYKI 464          

Query:  185 LLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGR--WRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGM-----GTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIART-KDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFT----DFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYP 1627
            L+ N+   R +P G        G P +G L  +       +  L K++G +F  ++G +   V++DY+ IR      ++ F+GR      Q+L G    GI+++ G      RRF+   + +FGM     G  +    I TE    +  L    G+ + +S +I   ++N+I   +M+  FS+ DPK      ++ E  R   +I    Y  +P +  FP I          +    ++ R  Q  I++H+++FD  N   DL+D +L + ++ K+     + F     + QLV+ +++LF AG ET  T   W   FM +  +   +V  E+   +G  RLPT  D + L  T + + E +R SS++PLA  H  T D E+N Y IP  S V+  + + H+DPN+WEKP EF P  F+  +  G ++    +   PFG+G+R C+G+ L RM+ F+FF S +  F ++    + E Q   +L+ N G    P
Sbjct:   43 LVRNYRELRKLPPG------PWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTLNG---YGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDY--IPTMQCFPSISTAKNKIAQNR---AEMQRFYQDVIDDHKRSFD-PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTE--GKVRK--PEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIA----LPEGQPLPSLKGNVGATITP 510          

Query:  185 LLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGR--WRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGM-----GTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIART-KDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFT----DFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYP 1627
            L+ N+   R +P G        G P +G L  +       +  L K++G +F  ++G +   V++DY+ IR      ++ F+GR      Q+L G    GI+++ G      RRF+   + +FGM     G  +    I TE    +  L    G+ + +S +I   ++N+I   +M+  FS+ DPK      ++ E  R   +I    Y  +P +  FP I          +    ++ R  Q  I++H+++FD  N   DL+D +L + ++ K+     + F     + QLV+ +++LF AG ET  T   W   FM +  +   +V  E+   +G  RLPT  D + L  T + + E +R SS++PLA  H  T D E+N Y IP  S V+  + + H+DPN+WEKP EF P  F+  +  G ++    +   PFG+G+R C+G+ L RM+ F+FF S +  F ++    + E Q   +L+ N G    P
Sbjct:   43 LVRNYRELRKLPPG------PWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTLNG---YGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDY--IPTMQCFPSISTAKNKIAQNR---AEMQRFYQDVIDDHKRSFD-PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTE--GKVRK--PEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIA----LPEGQPLPSLKGNVGATITP 510          

Query:  134 FPKMIWFFLLILISVVALLFNFLR-PRPIPKGLQKVPIEKGFPFVGILPL---LTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIR----NALIDNK-DNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLE----KCKGE--RIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPT-NNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV 1552
            F  +IW F   L+   A+LF  +R P+  P G    PI      V  L     +   +++ + R        +G+K+G   + +     AI     N  ID + D    R R F S LG     ++ TDG+     RRFI+R +  FG      +  +  E T LL+ L+    K  G+  RI++ D+   Y+ N +   L  + +  G P++  +     E+ +  D+   L+   P+L RF  I      +    +    ++  + +EIE HR T+   +E  DL+D +L  QD+     +    F+D  L+   L++FLAG ETT+    +    +    EIQ +  QEI + +G ER+P  + DR  L Y  A+  E +R+  +    + HR   DT ++ Y IPKD++V+       ++P  +  P  F P+ +L    +G++K    +  NPFG G+ +C+G+ LGR   F+F  ++LQ F++
Sbjct:    2 FYTVIWIFCATLL---AILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLG-----VLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLL-RF--IAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDE---GNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLF---DGHLKL--PEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          

Query:  134 FPKMIWFFLLILISVVALLFNFLR-PRPIPKGLQKVPIEKGFPFVGILPL---LTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIR----NALIDNK-DNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLE----KCKGE--RIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPT-NNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV 1552
            F  +IW F   L+   A+LF  +R P+  P G    PI      V  L     +   +++ + R        +G+K+G   + +     AI     N  ID + D    R R F S LG     ++ TDG+     RRFI+R +  FG      +  +  E T LL+ L+    K  G+  RI++ D+   Y+ N +   L  + +  G P++  +     E+ +  D+   L+   P+L RF  I      +    +    ++  + +EIE HR T+   +E  DL+D +L  QD+     +    F+D  L+   L++FLAG ETT+    +    +    EIQ +  QEI + +G ER+P  + DR  L Y  A+  E +R+  +    + HR   DT ++ Y IPKD++V+       ++P  +  P  F P+ +L    +G++K    +  NPFG G+ +C+G+ LGR   F+F  ++LQ F++
Sbjct:    2 FYTVIWIFCATLL---AILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLG-----VLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLL-RF--IAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDE---GNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLF---DGHLKL--PEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          

Query:  152 FFLLILISVV--ALLFNFLRPRPIPKGLQKVP-------IEKGFPFVGILPLLTFPILEYYERLIKK-HGPVFGMKMGLRTIFVLNDYQAIRNALIDN-----KDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVG-DPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTF--DVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIG---TERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTES 1579
            F   ILI  V  +L+ +  RP+  P G + VP         K    VG   +L       +ER  K     + G+K+G   + V   ++ ++   +        DNF  R R     +GTR  GI  TDG   + HR F ++ M   G G  +   +I+ E   LL  LE+ + + I+    +   + N++   +  K  +   D  L  + +++   ++  DI   L    P L     +      +   + L  +++      IEEHR+    D      DLI  +L +     +  ES  +F + QLV  +L+ F+AG +TTS   + +L  ++   ++Q K+  ++  S+    T+  P  + R+   Y  A + E+ R   + P+    R    T++  Y IPK++ +LI+L + H+D   W+ P EF PE F+    +   K    +   PFGMG+R+C+G++L R   F F V I+Q F V    P  ES
Sbjct:    6 FLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHIL-------FERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRT----MGTRK-GITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRH---VAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGES-STFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFI----DSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVL--PAGES 480          

Query:  158 LLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLT-FPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRL-FQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKL-NLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRK--DLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYP 1627
            +LI + V  LL ++++ +  PK     P     PF+G L  +    I   +    +K+G +F  ++    I VLN Y  ++       DN + R  L   S +   N G+V++ G +    RRF +  +  FG+G      +I  EC  L E +   +G       ++   ++N+I   +    F   D    NL+  I   +     IF  LY   P L +       L+    +K   L+ ++   +++++ EHR  +D ++   D ID FL + +  K  +++   F    L    L+LF+AG ETTST  +W L +M KY EIQAKV QEI   +G+ R P+ +DR ++ YT AV+ EI R+ +++PL ++  T+ DT +  Y IPK +LV+ +L +   D + WE P  F P HFL    +   K+  +D   PF +GKR C+GE L RM+ F+FF S+LQRF  +F+ P   +  + +L    G  R P
Sbjct:   15 ILIFLCVFLLLSDYIKNK-APKNFPPGPWS--LPFIGDLHHIDPNKIHLQFTEFAEKYGKIFSFRLFGSRIVVLNGYNLVKEVYTQQGDNLADRPTLPITSAIIGDNRGLVASSGYKWKHQRRFALTTLRNFGLGKKNLELSINFECGFLNEAISNEQGRPFNPRLLLNNAVSNVICVLVFGNRFEYSDHHFQNLLNKINESVYLEGSIFVHLYNMFPWLMQ-------LLPGPHKKLITLWQRVTDFVREKVNEHRADYD-QSSLRDYIDCFLAEME--KHKDDTAAGFDVENLCMCTLDLFVAGTETTSTTLYWGLLYMIKYPEIQAKVQQEIDAVVGSSRQPSGSDRDNMPYTNAVIHEIQRMGNIIPLNVVRTTSEDTRIEKYSIPKGTLVIGSLTSVLFDESEWETPHSFNPGHFL----DAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFTSVLQRF--TFSPP---AGVEPSLDFKMGFTRCP 487          

Query:  158 LLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLT-FPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRL-FQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKL-NLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRK--DLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYP 1627
            +LI + V  LL ++++ +  PK     P     PF+G L  +    I   +    +K+G +F  ++    I VLN Y  ++       DN + R  L   S +   N G+V++ G +    RRF +  +  FG+G      +I  EC  L E +   +G       ++   ++N+I   +    F   D    NL+  I   +     IF  LY   P L +       L+    +K   L+ ++   +++++ EHR  +D ++   D ID FL + +  K  +++   F    L    L+LF+AG ETTST  +W L +M KY EIQAKV QEI   +G+ R P+ +DR ++ YT AV+ EI R+ +++PL ++  T+ DT +  Y IPK +LV+ +L +   D + WE P  F P HFL    +   K+  +D   PF +GKR C+GE L RM+ F+FF S+LQRF  +F+ P   +  + +L    G  R P
Sbjct:   15 ILIFLCVFLLLSDYIKNK-APKNFPPGPWS--LPFIGDLHHIDPNKIHLQFTEFAEKYGKIFSFRLFGSRIVVLNGYNLVKEVYTQQGDNLADRPTLPITSAIIGDNRGLVASSGYKWKHQRRFALTTLRNFGLGKKNLELSINFECGFLNEAISNEQGRPFNPRLLLNNAVSNVICVLVFGNRFEYSDHHFQNLLNKINESVYLEGSIFVHLYNMFPWLMQ-------LLPGPHKKLITLWQRVTDFVREKVNEHRADYD-QSSLRDYIDCFLAEME--KHKDDTAAGFDVENLCMCTLDLFVAGTETTSTTLYWGLLYMIKYPEIQAKVQQEIDAVVGSSRQPSGSDRDNMPYTNAVIHEIQRMGNIIPLNVVRTTSEDTRIEKYSIPKGTLVIGSLTSVLFDESEWETPHSFNPGHFL----DAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFTSVLQRF--TFSPP---AGVEPSLDFKMGFTRCP 487          

Query:  158 LLILISVVALLFNFLR---PRPIPKGLQKVPIEKGFPFVGILPLL-TFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGR--WRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKL-NLIKNILTEIARTKDIFQFLYFTLP-ILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVS 1555
            +LI + V  LL ++++   P+  P G   +PI      +G L  +    I   + +  +++G +F  ++    I VLN Y  ++   I   DN + R    LF  ++G +  G++ + G +    RRF +  +  FG+G      +I  EC  L E +   +G       ++   ++N+I   +    F   D     L+KNI   +     I   LY   P +++R P     +++      L+ K+   +++++ EHR  +D  N   D ID FL + ++LK  +++   F    L    L+LF+AG ETTST  +W L +M KY EIQAKV +EI   +G  R P+ +DR ++ YT AV+ EI R+ ++ P+ L   T+ DT++ +Y IPK ++V  NL +   D + WE P  F P HFL    +   K+  +D   PF +GKR C+GE L RM+ F+FF S+LQRF  S
Sbjct:   15 ILIFLCVFLLLGDYIKNKAPKNFPPGPWSLPI------IGDLHHIDNSKIHLQFTKFAERYGNIFSFRLFGPRIVVLNGYNLVKEVYIKQGDNLADRPVLPLFYEIVGDK--GLILSSGYKWKHQRRFALSTLRNFGLGKKSLEPSINVECGFLNEAISNEQGRPFDPRLLLNNAVSNVICVLVFGNRFDYSDHHFQTLLKNISEAVYLEGSICNQLYNMFPWLMERLPGPHKTIIT------LWRKVTDFVREKVNEHRVDYDPSNP-RDYIDCFLTEMEKLK--DDTAAGFDVENLCICSLDLFVAGTETTSTTLYWGLLYMIKYPEIQAKVQEEIDAVVGGSRQPSVSDRDNMPYTNAVIHEIQRMGNIAPINLARSTSEDTQIGNYSIPKGTMVTSNLTSVLFDESEWETPHSFNPGHFL----DAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFS 467          

Query:  158 LLILISVVALLFNFLR---PRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGR--WRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKL-NLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRK--DLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYP 1627
            +LI + V  LL +F++   P+  P G   +PI      +     L   + E+ E    K+G +F +++    I VLN Y  ++       DN + R    LF  ++G +  G+V++ G +    RRF +  +  FG+G      +I  E   L E +   +G+      ++   ++N+I   +    F   D K   L+KNI   +     I   LY  LP L R       L+    ++   L+ K+   + +++ EH+   D  N   D ID FL + +  K  +++   F    L    L+LF+AG ETTST  +W L +M KY EIQAKV QEI   +G  R P+ +DR ++ YT AV+ EI R+ +++P+ L   T+ DT++  Y IPK ++V  NL +   D + WE P  F P HFL    +   K+  +D   PF +GKR C+GE L RM+ F+FF S+LQRF  +F+ P   +  + +L  N G    P
Sbjct:   18 ILIFVCVFLLLSDFIKNKTPKNFPPGPWSLPIIGDIHHIDP-SKLHLQLSEFAE----KYGKIFSLRLFGPRIVVLNGYNLVKEVYTQEGDNLADRAILPLFHDIIGDK--GLVASSGYKWKQQRRFALSTLRNFGLGKKNLEPSINLESGFLNEAISNEQGQPFDPRLLLNNAVSNVICALVFGNRFDYSDHKFQTLLKNINETVHLEGGICAQLYNMLPWLMR-------LLPGPHKRIIALWGKLIEFVGEKVNEHKVDHDPLNP-RDYIDCFLDEME--KHKDDTAAGFDVENLCICTLDLFVAGTETTSTTLYWGLLYMMKYPEIQAKVQQEIDVIVGGSRQPSVSDRDNMPYTNAVIHEIQRMGNIIPINLARTTSEDTQIEKYSIPKGTMVTSNLTSVLFDESEWETPHSFNPGHFL----DAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRF--TFSPP---AGVEPSLDYNLGATHCP 489          

Query:  311 RLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGR--WRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYF-TLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQF 1585
            +L K++GPV+ + MG RT+ VL+ Y+A++ AL++  + F  R    +FQ        GIV ++G+     RRF +  + +FGMG  RS   I  E   L E +E+  G+  +    +   ++N+I   + +  F    PK +        I R  +  + +   ++ + + FP +  F+ +     D   +  + + + +   +KT + ++    + D+FL++Q + K S ++   +     +  +  LF AG +TT T   W L  ++KY EIQAKVH EI DS+  ER P  +DRK+L YT AV+ EI R + +LP+ L+ +T+ D  +N Y I K + V   + +   D N WE P  F P+HFL    N   ++V KD   PFG G+R CIGESL RM+ F+FF S+LQ F  +    V+E + 
Sbjct:   67 KLSKQYGPVYTVHMGPRTVVVLSGYKAVKEALVNLSEEFGERDISPIFQDF--NEGYGIVFSNGENWKEMRRFALSNLRDFGMGKKRSEELITEEIKYLKEEIERFGGKPFETKLPLAMAISNVIALIVYSIRFEYNSPKFH------RAIVRANENAKLVGSPSVQLYNMFPWLRLFVANQKRVVDNVQESFKQIGEIVNGLKKTLNPQSP-RGIADKFLIQQQKDKESGKTDSLYNSNNFLTTINNLFGAGIDTTVTTLRWGLLLIAKYPEIQAKVHDEI-DSVIGERQPVPDDRKNLPYTDAVIHEIQRFADILPIGLLRQTSCDVYLNGYLIKKGTSVFPLIASVLRDENEWETPDSFNPKHFL----NKQGQFVKKDAFMPFGAGRRLCIGESLARMELFLFFTSLLQHFCFTPPPGVSEDEL 480          

Query:  239 PIEKGFPFVGILPLLTF--PILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKL-NLIKNILTEIARTKDIFQFLYFTLP-ILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRF 1546
            P  K  P +G L ++    P L + E   KK+GPVF +++GL    VL    A+++ALI++ D FSGR ++      ++  G+V  DG+   + RRF +  + +FGMG       I  E   L+E  +  + +    + I+   +ANII   L+N  F   DP L  LIK++   +         LY T P I+   P       S  T  + F K+   L++   + R   DV N+  DLID FL+KQ + KSS  S + F D  L   L +LF AG ETTST   W +  M KY +IQ KV  EI   IG+   P    RK + YT AV+ EI R ++++P+ L H  T D     YF+PK + V+  L +   D + ++KP EFYPEHFL  K N    +V  +   PF +GKR C+GE+L +M+ F+FF  +LQ F
Sbjct:   32 PGPKPLPLIGNLHMMNMKKPHLTFME-FSKKYGPVFSIQLGLNKAIVLCGADAVKDALINHGDEFSGRPKIPVFDQISKGYGVVFADGENWKVMRRFALSTLRDFGMGRKTIEDTIVEESGCLVETFKSHEAKPFDNTLILNAAVANIIVHILLNHRFEYQDPTLIKLIKSVSENVKIAGSPIVMLYNTYPSIMGWIPG------SHKTVFENFQKLSNFLKETFTKRRDQLDV-NDQRDLIDAFLVKQQEEKSS--SKKFFHDENLKVLLGDLFAAGMETTSTTLRWGILMMMKYPDIQKKVQDEIDRVIGSAE-PRLEHRKQIPYTDAVIHEIQRFANLVPIVLPHSITEDVTFRGYFLPKGTQVIPLLISVMQDKDYFQKPEEFYPEHFLDSKGN----FVKNEAFLPFSVGKRSCVGETLAKMELFLFFTKLLQNF 456          

Query:  239 PIEKGFPFVGILPLLTF--PILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRL--FQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKL-NLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRF 1546
            P  K  P +G L ++    P L + E L +K+G VF + +G   + VL     +R+ALI++ + FS R ++  F+    ++  G+V   G+   + RRF +  + +FGMG       I  E   L+E ++  +G+    + I+   +ANII   L+N  F   DP L  LI  ++  I         LY T P + R+        S  T  +   ++++ L++   +HR+  DV N+  DLID FL+KQ + K S  S + F +  LV  L  LF+AG ET+ST   W L  M KY +IQ KV  EI   IG+   P    RK + YT AV+ EI R +++ P++L H TT D     YFIPKD+ V+I L +   D + ++KP EFYPEHFL+ K N    +V  +   PF  G+R C GE+L +M+ F+FF  +LQ F
Sbjct:   32 PGPKPLPLIGNLHMMNMKKPHLTFME-LAEKYGSVFSVHLGTEKVVVLCGTDTVRDALINHAEEFSERAKMPIFEDF--SKGLGVVFGHGENWKVMRRFTLSTLRDFGMGKKTIEERISEESDCLVETIKSYEGKPFDNTLIMNAAVANIIVHILLNHRFDYQDPTLLKLINIVIDNIKIGGSPIVMLYNTYPSVVRW-----IPGSHKTLGENTAQLYKFLEETFTQHREQLDV-NDQRDLIDAFLVKQQEEKPS--SAKFFHNENLVALLANLFVAGMETSSTTLRWGLLLMMKYPDIQKKVQDEIDKVIGSAE-PRLEHRKLMPYTDAVIHEIQRFANIAPISLPHATTTDVTFRGYFIPKDTQVMIVLTSVLQDKDYFKKPEEFYPEHFLNSKGN----FVKNEAFLPFSAGRRICAGETLAKMELFLFFTKLLQNF 456          

Query:  221 KGLQKVPI-EKGFPFVGILPLLTF--PILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWR--LFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKL-NLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMS-----FTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRF 1546
            KG Q  P   K  P +G L ++    P L + E L +K+GPVF + +G     VL    A+++ALI+  D FSGR +  LF+     +  GIV  DG+   + RRF I  + +FGMG       I  E   L+E  +  KG+    + I+   +ANII   L+   F   DP L  LIK +   +         LY      + FP I  ++       F   ++ FN    IL++   EHR   DV N+  DLID FL+KQ + KSS  S + F D  L   +  LF AG ETTST   W +  M KY EIQ KV  EI   IG+   P    RK + YT AV+ EI R ++++P  L H TT D     YFIPK + V+  L +   D   ++KP EFYPEHFL  K N    ++  +   PF  GKR C GE+L +M+ F+FF  +LQ F
Sbjct:   28 KGSQNFPPGPKPLPLIGNLHMINMKKPYLTFME-LAEKYGPVFSVHLGANKAVVLCGTDAVKDALINYADEFSGRPKTPLFEQTF--KGNGIVFADGENWKVMRRFTISTLRDFGMGKKTIEDRIIEESCCLVETFKSHKGKPFDNTMILNAAVANIIVHILLKHRFEYQDPTLLKLIKGVNENVRNGARPIVMLY------NAFPSIIQWIPGTHKRIFANTQNFFN----ILKEIFIEHRDQLDV-NDQRDLIDTFLVKQQEEKSS--STKFFHDENLKVLIGNLFAAGMETTSTTLRWGILLMMKYPEIQKKVQDEIDRVIGSAE-PRLEHRKLMPYTDAVVHEIQRFANLVPNGLPHATTTDVTFRGYFIPKGTQVIPLLTSVLRDKAYFKKPEEFYPEHFLDSKGN----FLKNEAFLPFSAGKRTCAGETLAKMELFLFFTKLLQNF 459          

Query:  155 FLLILISVVALLFNFLRPRPIPKGLQKVPI-EKGFPFVG-ILPL-LTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIART-KDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPL 1630
            +L+++++V+ +L N+ R     K L   P   KG+P VG +  + L  P   Y E L KK+GPVF ++MG + + +L  Y+ +++AL+ + + F GR  +  +    +  G++ ++G+     RRF I  + +FGMG       I  EC+ L++     KG+    S I+ T +ANII   L+       DP    + N+ +E  +        +Y   P L   P         T +K+L  +++  L++   E++K FD+ ++    ID FL +Q +     E+   F +  LVR +  LF AG ETTST   W+L  M KY +IQ KVH EI   IG+   PT + R  + +T AV+ EILR + ++PL++ H TT D     YFIPK + ++  L +   D   ++ P +F P HFL  + N    ++ K+   PF  G+R C GE L RM+ FIFF S+LQ+F  SF  P   +     L ++ G    PL
Sbjct:   10 YLVLVVTVLYILSNWKR-----KALNNFPPGPKGWPLVGNVFSIDLKKPQRTYIE-LSKKYGPVFSVQMGRKKMVILVGYETVKDALVTHAEEFGGRAYIPVTKDLEKGLGMIFSNGENWKAMRRFTITTLKDFGMGKSTIEETIAHECSYLVQYFASFKGKPFDNSTILITSVANIIVAILLGHRMEYEDPVFLRLVNLNSEYVKLLGSPMVTIYNMFPALGFLPGCHK-----TVKKNL-KELYAFLKRTFVEYQKKFDIHDQ-RSFIDVFLARQKEEAKHPETYSYFHNENLVRLVRNLFSAGMETTSTALRWALLLMIKYPDIQEKVHDEISRVIGSVH-PTYSHRTQMPFTNAVIHEILRFADIVPLSVPHETTRDVHFKGYFIPKGTYIIPLLTSVLKDKTQFDAPEQFNPNHFLDSEGN----FLKKEAFMPFSAGRRACPGEILARMELFIFFTSLLQKF--SFRPPPGVTNIN--LSSDVGFTSVPL 483          

Query:  239 PIEKGFPFVGILPLLTF--PILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWR--LFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKL-NLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMS-----FTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRF 1546
            P  K  P +G L ++    P L + E L +K+GPVF + +G     VL    A+++ALI+  D FSGR +  LF+     +  GIV  DG+   + RRF I  + +FGMG       I  E   L+E  +  KG+    + I+   +ANII   L+   F   DP L  LIK +   +         LY      + FP I  ++       F   ++ FN    IL++   EHR   DV N+  DLID FL+KQ + KSS  S + F D  L   +  LF AG ETTST   W +  M KY EIQ KV  EI   IG+   P    RK + YT AV+ EI R ++++P  L H TT D     YFIPK + V+  L +   D   ++KP EFYPEHFL  K N    ++  +   PF  GKR C GE+L +M+ F+FF  +LQ F
Sbjct:   32 PGPKPLPLIGNLHMMNMKKPHLTFME-LAEKYGPVFSVHLGANKAVVLCGTDAVKDALINYADEFSGRPKTPLFEQTF--KGNGIVFADGENWKVMRRFTISTLRDFGMGKKTIEDRIIEESCCLVETFKSHKGKPFDNTMILNAAVANIIVHILLKHRFEYQDPTLLKLIKGVNENVRNGARPIVMLY------NAFPSIIQWIPGTHKRIFANTQNFFN----ILKEIFIEHRDQLDV-NDQRDLIDTFLVKQQEEKSS--STKFFHDENLKVLIGNLFAAGMETTSTTLRWGILLMMKYPEIQKKVQDEIDRVIGSAE-PRLEHRKLMPYTDAVVHEIQRFANLVPNGLPHATTTDVTFRGYFIPKGTQVIPLLTSVLRDKAYFKKPEEFYPEHFLDSKGN----FLKNEAFLPFSAGKRTCAGETLAKMELFLFFTKLLQNF 456          

Query:  221 KGLQKVPIEKGFPFVG-ILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTE--IARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV 1552
            KG +  P     PF+G  L + T    + +++L KK+G VF +  G R + VL  ++A++ AL+D  D+FSGR  +       +  G+  ++G++  I RRF + V+  FGMG       IQ E   LLE L K KG  I  +  +   ++N+I   +  K F   D +   +  ++ E  +  +K   Q       ++  FP   ++L       +L   +   +   ++ +  +FD  N   D ID FL+K  Q KS   +   F    LV   L LF AG ET S+   +    + KY E++AK+H+EI   IGT R P  +DR  + YT AV+ EI RL+ ++PL + H  T DT    Y +PK + V     +   DP  +  P  FYP+HFL   E G  K    D    F  GKR C+GE+L RM+ F++F SILQRF +
Sbjct:   29 KGGKLPPGPTPIPFLGNFLQVRTDATFQSFQKLQKKYGSVFTVYFGPRPVVVLCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLALSNGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHKVKGAPIDPTLYLSRTVSNVICSVVFGKRFDYQDQRFQSLMRMINESFVEMSKPWAQLYDMYWKVMQYFPGRHNYLY------NLIEDLKDFIASRVKINEASFDPSNP-RDFIDCFLIKMHQDKSDPHT--EFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLLKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVTRDTHFRGYLLPKGTDVYPLFGSVLKDPKYFRYPDAFYPQHFLD--EQGRFK--KNDAFVVFSSGKRICVGEALARMELFLYFTSILQRFSL 462          

Query:  293 ILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTL--PILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVF 1648
            +L+ + +L +KHG VF + +G R + VL   Q IR AL+D+ + FSGR  +  + L  ++ GI    G +    RRF +  M EFGMG       I+ E   L+E L+K +G  +  + +     ANII   +  + F   D +   + N++ +I      F    F L    L  FP +   ++    +++L + I       +E+H+ T D  +   D ID +L++ ++ KS+  +   F    L+  +L LF AG ETTS   H+ +  M KY  +  KV +EI   IG+ RLPT +DR  + YT AV+ EI R S ++P+ L H+   DT    Y +PK++ V   L +   DP  +E+P +F PEHFL    NG +K    +   PF  GKR C+GES+ R + FIFF +ILQ F V  A PV         + + GI + P  ++  F
Sbjct:   51 LLKCFIQLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVDHAEAFSGRGTIAAAQLVMQDYGIFFASGQRWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGVPLDPTFLFQCITANIICSIVFGERFDYTDDQFLHLLNLMYKIFSLLSSFSGQMFELFSGFLKYFPGVHRQIVK--KQQELLDYI----AHSVEKHKATLD-PSAPRDYIDTYLLRMEKEKSNHNT--EFHHQNLMMSVLSLFFAGTETTSATLHYGVLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDLVPIGLPHKVIKDTLFRGYLLPKNTEVYPVLSSALHDPQYFEQPDKFNPEHFLD--ANGALKKC--EAFLPFSTGKRICLGESIARNELFIFFTTILQNFSV--ASPVAPKDIDLTPKES-GIGKIPPAHQIYF 488          

Query:  293 ILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTL--PILDRFPRICDFLMSFTTRKDLFNKI-HRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVF 1648
            +L+ +  L +KHG VF + +G R + VL   Q IR AL++N + FSGR  +  + L  ++ GI  + G++    RRF +  M EFGMG       I+ E   L+E L+K +G  +  +       ANII   +  + F   D +   + N++ +I      F    F L   +L  FP +   +     ++++ N I HR+     E+HR T D  +E  D ID +L++ ++ KS+  +   F    L+  +L LF AG ETTST        M  Y  +  KV +EI   IG+ RLPT +DR  + YT AV+ EI R S ++P    HR T DT    Y +PK++ V   L +   DP  +E+P  F P+HFL    NG +K    +   PF  GKR C+GES+ R + F+FF SILQ F V  A PV         + + GI + P   +  F
Sbjct:   51 LLKCFIHLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVNNAEAFSGRGTIAAAQLVMQDYGIFFSSGERWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGAPLDPTFFFQCVTANIICSIVFGERFDYTDEQFLRLLNLMYQIYSLLRSFSCQMFELFSGLLKYFPGVHRQIAK--NQQEILNFITHRV-----EKHRATLD-PSEPRDFIDTYLLRMEKEKSNHNT--EFHHQNLMMSVLSLFFAGTETTSTTLCCGFLLMLMYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDIVPTGAPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDHFLD--ANGALK--KSEAFLPFSTGKRICLGESIARNELFLFFTSILQNFSV--ASPVASKDIDLTPKES-GIGKIPPTYQICF 488          

Query:  305 YERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRL-FQSLLG--TRNAGIV-STDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTL-PILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRA 1603
            +++L  ++G +F +++   ++ VLN   A+R AL+ + ++ + R  L F  LLG   R+ GIV +  G      RRF +  MH FG+G       +  E   L        G     + ++   + N+I   L    F   DP+   +  +L E  + +  F  ++  + P+L R P +   +  F  ++        +L + + EH+ T+D      DL D FL + ++ K + ES  SF D  L   + +LF AG  TTST   W+L  M  + ++Q +V QEI + IG  + P   D+  + YT AV+ E+ R + +LPL + H+T+ D E+  + IPK + ++ NL +   D  VWEKP  F+PEHFL    +    +V  +   PF  G+R C+GE L RM+ F+FF  +LQRF +S  D   +       RA
Sbjct:   61 FQKLRGRYGDLFSLQLASESVVVLNGLTALREALVKHSEDTADRPPLHFNDLLGFGPRSQGIVLARYGPAWRQQRRFSVSTMHHFGLGKKSLEQWVTEEARCLCAAFADHTGHPFSPNTLLDKAVCNVIASLLYACRFEYDDPRFIRLLGLLKETLKEEAGFLPMFLNVFPMLLRIPGLVGKV--FPGKRAFVT----MLDELLAEHKTTWDPTQPPRDLTDAFLAEVEKAKGNPES--SFNDENLRTVVGDLFSAGMVTTSTTLSWALMLMILHPDVQRRVQQEIDEVIGQVQCPEMADQARMPYTNAVIHEVQRFADILPLGVPHKTSRDIELQGFLIPKGTTLITNLSSALKDETVWEKPLCFHPEHFL----DAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSISVPDGQPQPSDHGVFRA 486          

Query:  230 QKVPIEKGFPFVG-ILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTL-PILDRFPRICDFLMSFTTRK-DLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVS-FADP 1567
            Q  P  K  P +G +L L +  +L    +L K++G VF + +G R + VL+ YQ ++ AL+D  + FSGR         TR  GI  +DG++  I RRF ++++  FGMG       I  E + LLE L K +G+      I+   ++NII   +    F   D +L      LT I    D F+ +      + + FP + D++     R    F  +  ++ + + EH+ + D  N   D ID FL K  Q K  ++ +  F    L+     L   G ET  T    +   + KY ++QA+V +EI   +G  R+PT  DR  + YT AV+ E+ R + V+P+ L HR T DT    + IPK + V+  L   H D + ++ P+EF PEHFL   +N + K  P     PF  G+R C+GE L RM+ FI+F SILQ F +    DP
Sbjct:   29 QLPPGPKPLPILGNLLQLRSQDLLTSLTKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERL------LTIIHFINDNFKIMSSPWGEMYNIFPSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLD-PNSPRDFIDCFLTKMAQEK--QDPLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLD--DNHSFKKSPA--FMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQPLVDP 465          

Query:  203 RPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQ-SLLGTRN-AGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQF-LYFTLP-ILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRH-LLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTE 1576
            +P  +P G+       G+P VG +P  +  + +  ++L KK+G +   ++G R    L +++ ++ AL  +K   S R   +   L G  N  G+V ++G     HRRFI+R + + GMG  R    IQ E   L++ L+K   + + +   I   + N+I K + +  +S+ D +      +LT        F   L+  LP +L   P      M     +D   ++   ++  I+EH+ T D  N  +DL+D +L+    L+  +E   S  + + VR  +++LF AG ETTST+  W++ ++ KY E+QAK+ +EI  ++    LP+   +  L Y  A + E+ R+ S++PL + H T  DTE+  Y +PK ++V+ +L  CH DP+ WEKP EFYPEHFL    +   K+V ++ L  F +G+R C+GESL RM+ F+F  +ILQ F  +F+ P  E
Sbjct:   21 KPSGLPPGIW------GWPLVGRMPSRSKHLADQVKQLRKKYGDIITWRIGTRVNVFLCNFKLVKTAL--SKFECSDRPDFYTFKLFGEGNDVGVVFSNGVMWQTHRRFILRQLRDLGMGKSRLEAAIQHEAACLVQELKKHTDQPMPLPKSINLAVLNVIWKLVADHRYSLQDQEGQYFTQLLTTTTDNMQGFALNLFNYLPWLLMITPDFVKNWMGVRVLRDGVCELKDYMKTFIKEHQATLDPSNP-KDLLDAYLI---DLQERKEDPLSTMNIETVRAVIMDLFGAGTETTSTMIRWTILYLMKYPEVQAKIQREIDAAVPRGTLPSLEHKDKLAYFEATIHEVHRIVSLVPLGVSHYTNQDTELAGYRLPKGTVVMSHLECCHRDPSYWEKPNEFYPEHFL----DDQGKFVKREHLVNFSVGRRVCVGESLARMELFVFLSAILQNF--TFSAPKGE 465          

Query:  143 MIWFFLLILISVVALLFNF--LRPRPIPKGLQKVPIEKGFPFVG-ILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRL--FQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFL--MSFTTRKDLFN--KIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV-SFADP 1567
            ++W   L++IS+   ++N   L P P P            P +G I  L    I + + +L K+ GPVF + +G R I VL+ Y+A++  L+++K+ FSGR  +  FQ     +N GI+  +G      RRF + ++ ++GMG   +   IQ E   L+E L+K KG+    + +I     N+I   L NK F   D K   + ++  E         F   + P +  +    D+L  +  + RK + N  +I +   ++ +EH ++ D+ N   D+ D  L++ ++ K S+E + +  +  +   L +LF AG ETTST   + L  + KY EI+ K+H+EI   IG  R+P   DR D+ Y  AV+ EI R  +++P  L H  T DT    Y IPK ++V+  L +   D + +  P +F PEHFL+  ENG  KY   D    F  GKR C+GE L RM+ F+   +ILQ F + S  DP
Sbjct:   11 LVWVATLLVISIWKQIYNSWNLPPGPFP-----------LPILGNIFQLDLKDIPKSFTKLAKRFGPVFTLHLGSRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEY---KNKGIIFNNGPTWKDVRRFSLSILRDWGMGKQGNEARIQREAQFLVEELKKTKGQPFDPTFLIGCAPCNVIADILFNKRFDYNDKKCLRLMSLFNE--------NFYLLSTPWIQLYNNFADYLRYLPGSHRKIMKNVSEIKQYTLEKAKEHLQSLDI-NCARDVTDCLLIEMEKEKHSQEPMYTMENVSVT--LADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRVPAVRDRLDMPYMDAVVHEIQRFINLVPSNLPHEATRDTVFQGYVIPKGTVVIPTLDSLLYDSHEFPDPEKFKPEHFLN--ENGKFKY--SDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDP 466          

Query:  152 FFLLILISVVALLFNFLRP----RPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFT-LPILDRFPRICDFLMSFTTRKDLFNKI---HRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVF 1648
            F +L+L     LLF+  R     R +P G   +PI        IL +    I + +    K +GPVF +  G+  + VL+ Y+ ++ ALIDN + FSGR  L  S   T   GI+S++G +    RRF +  +  FGMG       +Q E   L+E L K K      + I+     N+I   +  K F   D      +N LT I R    F+ L    + + + FP + D      T   L   +      ++++++EH+ T DV N   D ID FL+K +Q K +++S   FT   LV  + +LF+AG ETTST   + L  + K+ E+ AKV +EI   IG  R P   DR  + YT AV+ EI R   ++P  + H  T D +  +Y IPK ++++  L +   D   +  P+ F P HFL   ENGN K    D   PF  GKR C GE L RM+ F+F  +ILQ F +     V + +      A  GI+  P   +  F
Sbjct:    4 FVVLVLCLSFVLLFSLWRQSSGRRKLPPGPTPLPI-----IGNILQIDVKDICKSFSNFSKVYGPVFTVYFGMNPVVVLHGYETVKEALIDNAEEFSGRGILPISERITNGLGIISSNGKRWKETRRFSLTTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKD------ENFLTLIKRFTVNFRILTSPWIQVCNNFPLLIDCFPG--THNKLLKNVALTKSYIREKVKEHQATLDVNNP-RDFIDCFLIKMEQEKDNQQS--EFTIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVIHEIQRYIDLVPTGVPHAVTTDIKFRNYLIPKGTIIITLLTSVLHDDKEFPNPKIFDPGHFLD--ENGNFKK--SDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK---SVADLKNLNTTSATRGIISLPPSYQICF 487          

Query:  221 KGLQKVPIEKGFPFVG-ILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKD-LFNKIHRI---LQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV 1552
            +G +  P     PF+G +L +      + + +L KK+G VF +  G R + +L  ++A++ AL+D  D+FSGR  +       +  G+  ++G++  I RRF + V+  FGMG       IQ E   LLE L K KG  I  +  +   ++N+I   +  K F   D +   +  ++ E         F+  ++P    +      +  F  R + L+N I  +   +   ++ +  +FD  N   D ID FL+K  Q KS   S   F    LV   L LF AG ET S+   +    + KY E++AK+H+EI   IGT R P  +DR  + YT AV+ EI RL+ ++PL + H    DT    YF+PK + V   + +   DP  +  P  FYP+HFL   E G  K    D    F  GKR C+GE+L RM+ F++F SILQRF +
Sbjct:   29 RGGKLPPGPTPIPFLGNLLQVRIDATFQSFLKLQKKYGSVFTVYFGPRPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLALSNGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHKVKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMINE--------SFVEMSMPWAQLYDMYWGVIQYFPGRHNRLYNLIEELKDFIASRVKINEASFDPSNP-RDFIDCFLIKMYQDKSDPHS--EFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVYPLIGSVLKDPKYFRYPEAFYPQHFLD--EQGRFK--KNDAFVAFSSGKRICVGEALARMELFLYFTSILQRFSL 462          

Query:  293 ILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTL--PILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVF 1648
            +L+ + +L +KHG VF + +G R + VL   Q IR AL+D+ + FSGR  +  + L  ++ GI    G +    RRF +  M EFGMG       I+ E   L+E L+K +G  +  + +     ANII   +  + F   D +   + N++ +I      F    F L    L  FP +   ++    +++L + I       +E+H+ T D  +   D ID +L++ ++ KS+  +   F    L+  +L LF AG ETTS   H+ +  M KY  +  KV +EI   IG+ RLPT +DR  + YT AV+ EI R S ++P+ L H+   DT    Y +PK++ V   L +   DP  +E+P +F PEHFL    NG +K    +   PF  GKR C+GES+ R + FIFF +ILQ F V  A PV         + + GI + P  ++  F
Sbjct:   51 LLKCFIQLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVDHAEAFSGRGTIAAAQLVMQDYGIFFASGQRWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGVPLDPTFLFQCITANIICSIVFGERFDYTDDQFLHLLNLMYKIFSLLSSFSGQMFELFSGFLKYFPGVHRQIVK--KQQELLDYI----AHSVEKHKATLD-PSAPRDYIDTYLLRMEKEKSNHNT--EFHHQNLMMSVLSLFFAGTETTSATLHYGVLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDLVPIGLPHKVIKDTLFRGYLLPKNTEVYPVLSSALHDPQYFEQPDKFNPEHFLD--ANGALKKC--EAFLPFSTGKRICLGESIARNELFIFFTTILQNFSV--ASPVAPKDIDLTPKES-GIGKIPPAHQIYF 488          

Query:  155 FLLILISVVALLFNFLR---PRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVF 1648
            F+L +  +  + + F R    R IP GL++ PIE G+P +GI+P +  P+  Y   L +KHGP+F +++G+R + +L +YQ IR AL+D+   FSGRW++    + T ++GIV  DG      R FI++V+ +FGMG   S   +Q EC  LL  L+  +GE I  S IIP Y ANII+KF+MNK F   DP++  I+  + + ++  DI Q L+   PI D+   I  F +  T++  LF+K+ R+   EIEEH+   D  +EG+DLIDRFL++Q++L  S   V+SFTD QL+    E+F AGYETTST   WS+ FMS+Y++IQ KV++EIL+ IG ER+PT ND+K L YT AVMDEILRLSSV PL + HRT NDT V++YFIPK+SLV  N YACH DP++W KP EFYPEHFL   EN  +KY P+++L PFG+GKRQCIGESL RM+YFIFFVSILQR+QV F++ +++S F+E LR NEGI+RY  I  F+F
Sbjct:    3 FILSIFGLFIIWYCFSRVFKRRSIPNGLKETPIEYGWPILGIIPKIKGPMQNYLLELSRKHGPIFRIRLGMRDVVILGNYQTIRKALVDDAQIFSGRWKMKLVSVVTHDSGIVFKDGPVWSTQRSFILKVLRDFGMGKSISQDIVQGECLFLLNELDSLQGEIIDFSKIIPIYTANIISKFIMNKRFDRSDPRIKFIEYAIFQTSKQSDIVQRLHLMFPIFDKSTIISKFNLWITSKLQLFSKVERVFHDEIEEHKTNLDYNSEGDDLIDRFLLEQNRLSQSTGIVESFTDKQLIFMTFEMFGAGYETTSTTLGWSMLFMSRYKDIQKKVYEEILNVIGEERMPTMNDKKSLNYTQAVMDEILRLSSVAPLGIFHRTFNDTSVDNYFIPKNSLVFANYYACHTDPDIWLKPVEFYPEHFLIKCENDELKYSPREELIPFGIGKRQCIGESLARMEYFIFFVSILQRYQVDFSENISDSLFEETLRGNEGIIRYSKIKNFIF 503          

Query:  191 FNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVFNR 1654
            + F +   IPKGL++ PIE G P +GI+  +  P+  Y  +L KKHGP+F +K+G+R + +L++Y  I+ AL+D+  NFSGRWR+    L T ++GI+  DG      R F+++V+ +FG+G  +S+  +Q EC+ LLE LE  +G+ I  S IIP Y ANII+KF+MNK F   +PK+  I+ +L+E  + KDI Q L+   P  D     C+ +++FT++   F +I    ++EI+EH KT D  +EGEDL+DRFL+KQ+QLK     V SF D+QL+R  LELF AGYETTST   WS  FMSK+Q+IQ KVH EI++ IG ERLPT ND+K + YT AVMDEI R+SSV PLALIHRT ND  ++ YFIPK++L+  NLYACH D ++WEKP  FYPEHFL+  +NGN+KY P+D+L  F +GKRQC+GESL RM++FIFF SILQRF+V     + E +++EAL   +GI+R  ++N+F+F +
Sbjct:   18 YGFQKRNSIPKGLKETPIEYGLPILGIIHKIKEPMHNYLLKLSKKHGPIFRIKLGMRDVLILSNYDIIKKALVDDGQNFSGRWRMKLISLITHDSGIIFKDGQDWSTQRSFVLKVLRDFGLGKSKSVDLVQNECSFLLEELESLEGKIIDFSKIIPIYTANIISKFIMNKRFERENPKIARIEKMLSEEIKKKDIIQLLHIMFPKCDTSGLFCELIINFTSKWKEFLEIQNYFKEEIDEHLKTIDFNSEGEDLMDRFLIKQNQLKQQNIDVGSFNDWQLIRSSLELFYAGYETTSTTLCWSFLFMSKHQDIQQKVHNEIIEIIGKERLPTMNDKKSMNYTQAVMDEIFRMSSVAPLALIHRTLNDANIDGYFIPKNTLIFPNLYACHFDRDIWEKPMIFYPEHFLTEDDNGNLKYTPRDELILFSIGKRQCLGESLARMEFFIFFTSILQRFRVKLVKELNEKEYEEALLGKDGIIRGSIVNDFIFTK 505          

Query:  239 PIEKGFPFVGILPL--LTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPK-LNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTE 1576
            P  + +PF+G LPL  L  P    ++ L KK+GPVF  +MG + I +L  Y+ ++ AL++  D F+ R  +       R  G++ + G+   + RRF++  + ++GMG       I  EC  L +  E  KG+  + + I+   +ANII   L+ K +   DP  + L+K +   I         LY   P L  F   C    +    +D   ++H  +Q    EH K  DV N+   LID FL++Q + K+  +  + F +  L   +  LF AG ETTST   W L  M KY EIQ+KV +EI   IG+   P    R  L YT AV+ E+ R +++LP+ L H TT D  +  YFIPK + +L  LY+   D + WEKP +FYPEHFL    + + K+V +D   PF  G+R C GE+L RM+ F+FFVS+LQ+F    A  +T+
Sbjct:   50 PGPRPWPFIGNLPLVDLKRPYRTMFQ-LWKKYGPVFRFQMGSQNIVILAGYETVKEALVNQADAFAERPMVPMFEEFARGYGVLFSHGENWKVMRRFMLTALRDYGMGKRTIEDKIVEECHFLKQKFESYKGKPFETTVIMNAAVANIIVSILLGKRYEYEDPTFVRLLKLVNENIRLAGSPSVTLYNMFPALGFF---CGGRKTVLKNRD---EMHAFIQATFIEHMKVLDV-NDQRSLIDAFLVRQQEEKNKNQDNKFFHNENLKSVVGNLFAAGMETTSTTLRWGLLLMMKYPEIQSKVQEEIAKEIGSAH-PQTEHRSKLPYTDAVIHEVQRFANILPMNLPHATTVDVTLKGYFIPKGTDILPLLYSVLYDESQWEKPFQFYPEHFL----DSDGKFVKRDAFLPFSAGRRMCAGETLARMELFLFFVSLLQKFTFQPAPGMTK 485          

Query:  272 LPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNK--DNFSGRWR--LFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLM-----SFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVFNRIQ 1660
            LP  TF  L  +    K++G +   ++G R   VLN Y A++ AL+  +  D FSGR       SL  T   GIVS++G+    HRRF ++V+ +FG     +  +I  E   L +         +  ++++   +AN+I+  L        D +         E  +  D+ +F+    P+L + P +   L       +  +++L    H   Q +I+ HR      +   D +D FLM+Q++L   ++   +F DFQL R L ELF+AG +TTS    W+L +   Y E QA+V  EI   IG +RLP + DRK + YT A +DE+ R +++ P A++HR   D E   Y I  D L++ NLY  H DP +W  P  F PE FL+       +Y P + L PFG+GKR C+GESL R + F+F   ILQ+       P +    ++    ++GIV  P  +  +F+  Q
Sbjct:   59 LPRPTF--LAAHADWRKRYGDLVSYRLGARRFVVLNSYAAVKEALVSQEFGDVFSGRMNSNYINSL--THGKGIVSSEGELWREHRRFALKVLRDFGFARAGTEDSIHQELQDLRDQFNTAGEAGVDTTEVLCRAIANVISMMLFGYRAGSQDDRFEAFLAATQENLQGGDLARFIPVGFPLLYQIPGVMRLLELLGVDVYVVQRNL-KVTHGFCQMQIDAHRAQLAGVSSPNDFLDAFLMEQEKLNGRKKD-HTFDDFQLKRTLTELFVAGTDTTSNTIRWALLYACLYPECQARVQAEIDAQIGRDRLPEHRDRKRMPYTLAFIDEVQRFATLAPFAVLHRCPRDVEFMGYDISSDDLIMTNLYGIHHDPELWSSPEAFQPERFLAVDTG---EYQPNEHLVPFGVGKRACLGESLARQELFLFIAGILQQHSARL-HPDSVKNLEDIKIGSDGIVHAPGAHRIIFSARQ 520          

Query:  272 LPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNK--DNFSGRWR--LFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLM-----SFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVFNRIQ 1660
            LP  TF  L  +    K++G +   ++G R   VLN Y A++ AL   +  D FSGR       SL  T   GIVS++G+    HRRF ++V+ +FG     +  +I  E   L +         +  ++++   +AN+I+  L        D +         E  +  D+ +F+    P+L + P +   L       +  +++L    H   Q +I+ HR      +   D +D FLM+Q++L   ++   +F DFQL R L ELF+AG +TTS    W+L +   Y E QA+V  EI   IG  RLP + DRK + YT A +DE+ R +++ P A++HR T D E   Y I  D L++ NLY  H DP +W  P  F PE FL+       +Y P + L PFG+GKR C+GESL R + F+F   ILQ+       P +    ++    ++GIV  P  +  +F+  Q
Sbjct:   59 LPRPTF--LAAHADWRKRYGDLVSYRLGARRFVVLNSYAAVKEALASQEFGDVFSGRMNSNYINSL--THGKGIVSSEGELWREHRRFALKVLRDFGFARAGTEDSIHQELQDLRDQFNTAGEAGVDTTEVLCRAIANVISVMLFGYRAGSQDDRFEAFLAATQENLQGGDLARFIPVGFPLLYQIPGVMRLLELLGVDVYVVQRNL-KVTHGFCQMQIDAHRAQLAGVSSPNDFLDAFLMEQEKLNGRKKD-HTFDDFQLKRTLTELFVAGTDTTSNTIRWALLYACLYPECQARVQAEIDAQIGRNRLPEHRDRKRMPYTLAFIDEVQRFATLAPFAVLHRCTRDVEFMGYDISSDDLIMTNLYGIHHDPELWSSPEAFQPERFLAVDTG---EYQPNEHLVPFGVGKRACLGESLARQELFLFIAGILQQHSARL-HPDSVKNLEDIKIGSDGIVHAPGAHRIIFSARQ 520          

Query:  299 EYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYF-TLPILDRFPRICDFLMSFTTRKDLFNKIHRI---LQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRF 1546
            ++Y +  KK+GPVF +      + V++ YQA+++++I   + FSGR      L  +   G++ ++GD+    RRF I  + +FGMG       ++ E + L++             D+I   + N+I   ++   F   DP L L       I      F FL   T    + FP+I  F        D+ + +      L++E+E   KT D     +D I+ FL++ ++ K +  +   F    L+     LF AG ETTS+     L +M K+ +IQAKV +EI + +G  R P+  DR+++ YT AV+ EI R   + P ++ H   NDTE N+Y IPK ++VL  L +   DP +W+ P  F PE+FL   ENG  K    D    FGMGKR C+GE++ R++ FIFF S+LQ F
Sbjct:   59 KHYLQFSKKYGPVFTLWFANTPVVVISGYQALKDSMIGMGEEFSGRANYPLLLKVSNGYGVLVSNGDRWKQLRRFCITTLKDFGMGRQSIEEKVREETSYLVQTFSTFGDSAFNPKDLISEAVCNVICSVMLGHRFESDDPLLKLF------ITAVNKYFHFLNSPTGQAYNIFPKIVSFFPG--KIHDVLSAVQETKASLKREVEARWKTLDPSAPPQDFIEAFLLRMEEEKHNPNT--EFNYENLLSTSWNLFSAGMETTSSTLRQGLLYMMKHPDIQAKVQKEIDEVLGPHRSPSIADRQNMPYTDAVVHEIQRSMDLTPTSVPHYMLNDTEFNNYLIPKGAIVLPLLSSVLSDPKLWKNPDCFDPENFLD--ENGRFK--KNDGFVAFGMGKRACLGEAMARVELFIFFTSLLQHF 464          

Query:  143 MIWFFLLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQT-HIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKD-IFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQF 1585
            ++W F    I ++ L     RP+  P G + VPI     F  +  L     L+ +ER  +++G V+ +  G R + +L  ++A++ AL+    +FSGR +       T+  GIV  D +     HRRF +  +  FGMG       I  E   L+ECLEK  G  +          +NII   L    ++ GD  LN+    +TE+A+  +  +  +Y T P+L   P      + F   ++ +  + +I    + +++ +  V+ E E+ +  +L   D+L        SF + QL R++++L  AG ETTS     +  ++  + +IQ K  +EI + +  +   +  DR+ + Y  AVM E  R+ S +PL++ H TT+DTE+  Y IPKD+ +L NLY+   +   W+ P EF P +FL+ K     ++   +   PF  G R C+GESL RM+ F+  V++L+RFQ  + +   E  F
Sbjct:    7 LVWGF----ICLIFLFIRIQRPKNFPPGPRPVPI-----FGNLFQLNITNPLKDFERFAEQYGNVYSVYFGGRPVVILTGFKAVKEALVTKAADFSGRPKNVLISDVTKGKGIVFLDYNSMWKEHRRFALTTLRNFGMGKQSMEERILGETEHLVECLEKRVGGTMDPQTFFHNATSNIIYLVLFGTRYNYGDETLNMYVKRITELAKIANGPWGMIYDTFPMLRGLP------LPFKKAEENYETLAKISANVVNKYKPS-RVQGEPENFVGCYL---DELDKRGNDGSSFNEAQLARYIVDLHAAGTETTSNTLLTAFLYLITHPDIQEKCQREIDEVLEGKAHVSFEDRQKMPYVQAVMHESQRIGSTVPLSVPHCTTSDTELMGYTIPKDTFILPNLYSVLNEEGQWKFPHEFNPANFLNEKG----QFEKPEAFMPFSAGPRTCLGESLARMELFLISVTLLRRFQFFWPEDAGEPDF 466          

Query:  161 LILISVVALLFNFLR---PRPIPKGLQKVPIEKGFPFVGILPLL-TFPILEYYERLIKKHGPVFGMKM-GLRTIFVLNDYQAIRNALIDNKDNFSGR--WRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKL-NLIKNILTEIARTKDIFQFLYFTLP-ILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRF 1546
            ++   V  LL  +LR   PR  P G   +P      F+G L  + T  I   +    +K+G +F +++ G R + V+N Y+ ++   ++  D+F+ R  + LF  +   ++ G+V++ G      RRF +  +  FG+G      +I  EC  L+E +   +G R     +I   ++N+I   +    F   + +  +L+K +         I+  +Y  +P I+ R P     ++       L+  +   ++ +++EH+   D  N   D ID FL + ++ K  ++    F+   L    ++LF+AG ETTST  +W L +M+KY EIQAKVH EI   +G+ R P+  DR +L YT AV+ EI R+ +++P  L   T+ D ++  Y IPK + V  NL +   D   WE P+ F P HFL    N +  +  ++   PF  GKR C+GE L RM+ F+FF S+LQRF
Sbjct:   17 VLFFCVFLLLVEYLRNKAPRNFPPGPPTLP------FIGNLHTIDTTRIHLQFIEFAEKYGNLFSIQIFGPRAV-VVNGYKLVKELYVNQGDHFADRPVFPLFHDIF--KDKGLVASSGYAWKQQRRFALTTLRNFGLGKKSLEPSILLECRYLIEAMSNEQGNRFNPQFLINNAVSNVICVLVFGSRFEYSNSEFQDLLKMMNQAFYLEGTIWAQMYNMVPRIMRRLPGPHQRVIQ------LWGNVFNYVRAKVDEHKMDRDFSNP-RDYIDCFLEEMEKRK--DDKAADFSIENLCFCAMDLFIAGTETTSTTLYWGLLYMTKYPEIQAKVHAEIDQVVGSSRQPSMMDRDNLPYTNAVIHEIQRMGNIIPFNLARATSKDVQIGEYTIPKGASVFGNLTSVLFDETEWETPKSFNPGHFL----NNDGSFRRREAFMPFSAGKRVCLGEQLARMELFLFFSSLLQRF 465          

Query:  158 LLILISVVALL--FNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTF--PILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIAR-TKDIFQFLYFTLPILDRFPRICDFLMS-FTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTES 1579
            +L+ + V+AL+   N  RP+ IP G    PI    PF+G +  L F  P++ +  ++ +K+G V  + +      +L+ Y++ + AL++  D F+ R     +   +R  G++S+ G      RRF + V+  FG+G       I  E   L E L+K +G       ++   + NII   +    F   D   + I     ++ +   + +  LY      +R P +  +L     T     +KI   +Q EI+ HR+ ++  N   D ID +L   D+++  ++S   FT+  L+  +++LF AG ETTS    W+L +M+KY E+Q KVH EI   IG  R P+ NDR  + YT AV+ E+LR ++ L +      + DT +  Y IPK   V   L A   D N +  P EF P HFL   ENG  K++ K+   PF +GKR C GE +  M++F+FF S++Q F  SF  P  E+
Sbjct:   21 ILVFLCVLALVKYLNDHRPKNIPPG----PIP--LPFLGNVLSLDFREPVVSF-SKISEKYGDVSTLYLAGEMCILLSGYKSFKEALVEQADIFAERAYYPVNDRLSRGLGLISSSGYAWSHQRRFAVSVLKHFGVGKKSLEHAILQESRYLCEALQKERGLAFDPDRVVTNAVTNIICSLVFGHRFEYDDQHFHQILMYFDDVVQLPANFWGQLY------NRLPALMPWLPGKHQTAFSSLSKIKVFIQDEIQRHRQDWNPSNP-RDYIDCYL---DEIEKCKDSKAEFTEENLICCVVDLFAAGTETTSNTILWTLLYMAKYPEVQEKVHAEIDQVIGQARQPSMNDRPLMPYTYAVIHEVLRAANALNITPPRVASRDTTIGGYLIPKGVTVFPLLRAIMQDKNEYSTPDEFNPGHFLD--ENG--KFLKKESFIPFSIGKRTCPGEQMVHMEFFLFFTSLMQSF--SFHAPDGET 477          

Query:  251 GFPFVG-ILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGR-WRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLN-LIKNILTEIARTKDIFQFLYFTLP-ILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVS 1555
              PF+G IL + +     Y  +L K +  +F M++G + + +L  Y+ ++ AL++  DNF  R +      + + N G+ +++G+     RRF +  +  FG+G       I  E   LL+ +++ KG+    S +    ++NII + +  + +   D     ++K     I     I+  LY + P I+   P   + + S       +  I   +++ +++H+   D  N   D +D FL++++   +S +    F+D  LVR  L+LFLAG ETT+T   W+L +++K  EIQ KV +EI   IG  R P   D+ ++ YT AV+ EILR   ++PL+       DT +  Y IPK + ++  L++   D + WE P  F P+HFL  KE    K+V +D    F  GKR C+GE L RM+ F+FF  + Q+F+ S
Sbjct:   43 ALPFLGNILDIASPQPHIYLTKLGKAYNNIFSMRIGQQKMILLTGYKMVKEALVNQTDNFVDRPYSPLAERIYSGNGGLFTSNGNLWKKQRRFALSTLRNFGLGKKTMELAICEESHFLLDEMDRHKGQAFDPSGLFNNAVSNIICQLVFGQRYDYADYDFQQMLKYTSEAIHLEGSIWGRLYESFPNIMKHLPGRHNVIFSN------YEHISEFIKKNLDKHKANLDPSNP-RDYMDSFLIEKE---NSHDPADGFSDKNLVRCTLDLFLAGTETTTTSLGWALIYLAKNPEIQDKVQEEIDRVIGQSRQPGMADKPNMPYTEAVIHEILRRGDIVPLSGPRVAAKDTTLGGYAIPKGTTIMPILHSVLFDEDEWETPNSFNPQHFLD-KEG---KFVRRDAFLAFSAGKRVCLGEQLARMELFLFFTCLFQKFRFS 467          

Query:  161 LILISVVALLFNFLRP-----RPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRL-FQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPK----LNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDL----FNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPL 1630
            LI +++  ++F  LR      +   + L   P  K  PF+G + L   P +   E + K++G V  + +G  ++  ++ YQA++  L+     F+ R    F   +      I +  G     HRRF +  +  FG+G       IQ E   L+E  ++ KG        + + + NII   +  K +   D +    L+L++N L                  +L     I  FLM F   + +      K  + ++  I E   T D   +   LID +L    QL+  +    SF++  L+   L+LF+AG ETTST   W L +M  + EIQA+ H+EI   +G++RLP   DR  L Y  AV+ EI R S+++P    H TT D +   Y IPK +++++N+ +   D N W+ P EF PE+FL   E+G  K+V  D   PF  G R C+GE+L +M+ F+FF S+LQ F+  + D V+       L+  +    Y L
Sbjct:   24 LISLAIFCIIFLVLRAILQEVKATKRPLDFPPGPKVIPFLGNVSLFKKPDVALDE-VTKQYGEVCSVMVGKISMVFVSGYQAVKEVLVHQGHEFADRPNTPFNKKVNGGLGIIFAPYGKYWMQHRRFTLSTLRNFGLGKSSIEQTIQAEVGFLIEAFKQ-KGSAFDPHYDLNSAVGNIICSMVKGKRYEYSDKQFQDFLHLVENNLQ-------------LQSGLLGTLCNIFPFLMDFPGPQQIIFKSMAKSKQFIRDIISERHATRD-PIKPMCLIDAYL---SQLEKEDNPNSSFSEQSLIMLALDLFIAGAETTSTTLRWGLLYMMMHPEIQAQCHEEIDKIVGSDRLPCMEDRHSLPYLDAVIHEIQRFSNIVPFGAPHATTADVKFRQYLIPKGTIIMVNMKSVLSDENHWKTPYEFSPENFLD--EDG--KFVKPDAFLPFSAGPRVCLGENLAKMELFLFFASLLQHFEFYWPDLVSAPTLGYILQITKAPKSYKL 504          

Query:  308 ERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGR--WRLFQSLLGTRNAGI-VSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIP-----TYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTK-DIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV----SFADPVTESQFQEAL 1597
            + L KK+G V  + +G   + +++ Y+A++  L++    F+ R    +F  L  T+N GI ++  GD     RRF +  +  FG G       I  E   L+E  ++      + S   P       + NII   L    +   + +   + ++L  + + + +    L    P L + P        +     + +K+  +L   + EHR T D  N   DLID +L + D+ K +  S  SFT   L++ L+ELF+ G ETTS    W L FM    +IQA+ H EI   +G+ER P   DR+ L Y  AV+ EI R  +VLPL ++H T+ D + N Y  PK + V++NL +   D   W+ P +F P+HFL    + + + +  D   PF  G R C+GESL +M+ F+FF S+LQ F+     S + P   ++F   L
Sbjct:   64 QELAKKYGEVCTIMLGSTPVVLVSGYEAVKEVLVNRGHEFADRPITPIFTKL--TQNIGIALAPYGDPWKQQRRFALSTLRNFGFGKATIADKISIEAKYLIETFKQ------ETSAFDPHLNLNNALGNIICCLLNRNRYDYDNEQFQKLTHLLEYLVQLQAEPLVILCNVFPFLLKLPG------PWQKVFHIHSKLQCLLNDIVSEHRATKDQHNP-RDLIDSYLAQIDKEKDNPNS--SFTHQSLIQILIELFIGGLETTSNTLRWGLLFMMMNPDIQARCHGEIDRVVGSERPPCMTDRRSLPYLDAVIHEIQRFGNVLPLGVLHATSKDVQFNDYLFPKGTHVMVNLMSALHDDIHWKTPNKFNPDHFL----DKDGQCIQSDAFLPFSAGPRVCLGESLAKMEIFLFFTSLLQHFEFYWPNSVSPPTLAAKFSTTL 485          

Query:  140 KMIWFFLLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFPIL-EYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRL--FQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTE-IARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQ 1549
            KM  + LL +++V+ L   F   R   +G    P  +G P VG L  L    L    ++L + +GP++ + +G   + VL   + I+ AL+   + F  R  +  F+  LG    G++ + G Q    RRF + ++  FGMGT      I  E   L+  +E  + +       I    AN+I        +   +     + +I+TE +  + + +  ++ + P+L  FP            K + N     +Q  IEEH     ++ E  D +D F+ K+  ++ S     +F+D  L+     LF+AG ETTS    W +  M  Y ++Q +V +EI   +G+ R P   DR  + YT A + EI R +++LP+A  H TT DT++  YF+PK + V+  +++   + ++WE P +F P HFL    +GN  Y   D +    +G R C+G++L RM+ F+FF ++LQRF 
Sbjct:   11 KMPTWVLLRVVAVLFLWLGFWWLRREQRGFPPGP--RGLPLVGNLFQLDLKALPASLDKLSETYGPIYSVSLGQTRVVVLVGNEIIKEALVTQAEMFIDRPEIPVFKKSLGNYE-GLLLSHGWQWRARRRFTLMMLRNFGMGTKSIEEKIAEEAEFLVRAIENKQEKPFDAHSEINKSAANVICSITFGDRYDWNNKTFVKLMDIITENVELSGNDWSQIFNSFPVLKYFPGPHQ---RINKNKVVLNAF---IQARIEEHDMA-RIQGEPRDYLDAFIDKR--IEDSMNPDTAFSDIALINTTANLFVAGSETTSATLKWGILLMLTYPKVQEQVQEEIDRVVGSNRRPACADRACMPYTNATVHEIQRYANILPMAFPHATTCDTKLRGYFLPKGTQVIALIHSALREKSLWEAPEQFNPGHFLD--IDGNF-YNRNDFMAFSAVGPRICLGKNLARMEVFLFFTALLQRFS 469          

Query:  653 IPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQF-LYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQA-KVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPL 1630
            I   ++NII   +    F   D +   + ++  E  R +  ++  +   +P L+ +P     +     + +LF       Q+ I EHR+T +   +  DLID +L + +  K S++   +FTD  L+  + +LF+AG ET+ST   W+L +M  Y +IQA +  +EI + IG +R P   DR +L YT AV+ E  R+++V PL ++H TT D +   Y IPK + VL+NL +   D   W+ P EF P+HFL    +   ++V  D    F  G R C+GE+L RM+ F+FF S+LQRF+  + D  +   F  A    EG+ R P+
Sbjct:   10 INNAVSNIICSIVFGNRFDYDDKRFRNLLHLFAENFRIEGGWRGKICIFMPWLEDWPGPHQLIFRNADKVNLF------FQERIREHRQTREA-GQPRDLIDAYLDEME--KESQDPESTFTDGNLLNVVGDLFIAGTETSSTTLRWALLYMMAYPQIQAERCQREIDEVIGGDRSPNTTDRANLPYTDAVIHEAQRMANVAPLGVLHSTTTDVKFRGYNIPKGTKVLLNLTSVLHDETQWKTPNEFNPDHFL----DNTGQFVKPDAFLAFSAGPRVCLGENLARMELFLFFTSLLQRFKFHWPDATSRPNFVAA----EGLSRAPV 320          

Query:  308 ERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGR--WRLFQSLLGTRNAGI-VSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTK-DIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV----SFADPVTESQFQEALRAN 1606
            + L KK+G V  + +G   + +++ YQA++  L++    F+ R    LF  L  T N GI ++  GD     R F +  +  FG G       I  E   L+E  ++   E      I+ + + NII   L    +   + +   + ++L  + + + +    L    P L + P     +    T      K+  +L+  + EHR T D  N   DLID +L   D+ K +    +SFTD  L+  L+ELF+ G ETTS    W L FM    +IQA+ H+EI   +G++R P   DR+ L Y  AV+ EI R  ++LP  ++H T+ D + N Y  PK + V++NL +   D   W+ P +F P++FL  K+   IK    D   PF  G   C GESL +M+ F+FF S+LQ F+     S + P   ++F+  L  +
Sbjct:   60 QELAKKYGEVCTIMLGSTPVVLVSGYQAVKEVLVNRGHEFADRPITPLFTKL--THNIGIALAPYGDTWKQQRGFALSTLRNFGFGKATITDKISIEARYLIETFKQETSE-FDPKFILNSAVGNIICSLLNGIRYDYNNEQFQKLTHLLEHLVQLQAEPLVILCNVFPFLIKLPGPWQKVFHIHT------KLQCLLKDIVSEHRATKDQHNP-RDLIDSYLAHIDKEKDNPN--RSFTDQTLILLLIELFIGGMETTSNTLCWGLLFMMMNPDIQARCHEEIDKVVGSQRPPCMKDRRSLPYLDAVIHEIQRFGNILPFGVLHPTSKDVQFNEYVFPKGTHVMVNLMSAFYDDIHWKTPHKFNPDNFLD-KDGQCIK---SDAFLPFPAGPCVCFGESLAKMELFLFFTSLLQHFEFYWPNSASPPTLAAKFRTTLSPH 484          

Query:  767 KDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSE---ESVQSFTDF-QLVRHLLELFLAGYETTSTIFHWSLFFMSKYQ-EIQAKVHQE---ILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNS-YFIPKDSLVLINLYACHVDPNVW-EKPREFYPEHFLSPKENGNIKY-VPKDQ--LNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEA 1594
            K IF   + T P LD  P          +RK  F        +++   R+   VK   ++L++ +  +Q    +S+          D+ QL  +++ + +AG+E    +F+ SL+ ++KY  E Q K+ +E   I D  G   LP  N         A + E++R+   L   +   TT   ++ +   IPK   V  N +    DP  W     +F PE + S  E     + + K++  +  F  G+R C+GE L   +  I    +L++F+ S  DP  E +   A
Sbjct:  210 KQIFHPFFLTFPFLDVLP--------IPSRKKAF--------KDVVSFRELL-VKRVQDELVNNYKFEQTTFAASDLIRAHNNEIIDYKQLTDNIVIILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRKEVNGITDPKGLADLPLLN---------AFLFEVVRMYPPLSTIINRCTTKTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSL-DPEWEEKLTPA 471          

Query: 1004 QSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEIL----DSIGTERLPTNNDR-KDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQV 1552
            + FT+ ++   +     A  + +S++  W    ++   ++ AK+ +E L    + + TE    N D  + + YT  V+ E LR    + +       N     +Y  PK ++++  LY    DP V+E P EF PE ++   +    K   K+ L  FG G   C+G++       I F ++L +F +
Sbjct:  319 REFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTE---LNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVEGSKASEAK---KNWLV-FGCGPHVCLGQTY----VMITFAALLGKFAL 495          

Query:  758 ARTKDIFQFLYFTL-----PILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQE---ILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEV--NSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKEN------------GNIKYVPKDQLNPFGMGKRQCIGESLGRMQ 1510
            A+    F +LY  L     PI   FP +   L  +  R      I       I+E RK  D+++   DLID  LMK    K   +     TD ++   L+ + + G  T++    W L  +++  ++Q ++++E   +LD  G ++  T +  +++      + E LR+   L  +L  +   D  V   SY IP    VL++    H+    +    +F    +     +            G I         PFG G+ +CIGE     Q
Sbjct:  219 AKLDTDFAYLYSDLDKGFTPINFVFPNLP--LEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDR--DLIDS-LMKNSTYKDGVK----MTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLD--GGKKELTYDLLQEMPLLNQTIKETLRMHHPL-HSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQ 479          

Query:  314 LIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTD--GDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFL-MSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLN--PFGMGKRQCIGESLGRMQYFIFFVSILQRFQVS 1555
            L K +G VF +K+G   I V+N  +A R AL+   ++F+GR  L+ + L +RN   ++    G      R+     +  FG G       I  E   L++ L   +G      D +   + NII  F+    + + DP+ + + +   +  +        +    ++D FP +           K+       +LQ++ +EH  T++      DL D  L+  ++    E +    T+  ++  + ++F AG ETT+T   WSL ++ +  ++Q ++HQ+I + +G +R P  +DR++L    A + E+LR SS++PL   H TT DT +  Y +PKD++VL N++  H DP  W  P EF P  FL  K     K++    L+  PF  G+R C+ ESLG+MQ F+F   +L +F+ S
Sbjct:   15 LAKSYGEVFRLKVGSHRIVVVNSIEAAREALVRRANDFAGRPMLYTASLISRNGTDIAFGDFGPLWKQQRKIAHSALRMFGSGLKPLEEKITVEADELIKRLSLVEGRAHNPKDDVNLAVLNIICSFVFGSRYDMDDPEFHTVVDYTEQFVQG-------FRAASLVDYFPWLRHLPNKGLRQIKEACQNRDVVLQKKYQEHLVTYE-HGVIRDLTDA-LLSANKASQEESAYLPMTEDHIIMTMNDIFSAGLETTATSILWSLVYLIRNPKVQEQLHQQIDEVVGRDRAPELSDRENLPLIEATIAEVLRSSSLVPLLFPHSTTTDTHLRGYEVPKDTIVLFNVWNMHHDPQRWSNPDEFDPTRFLDDKG----KFICPATLSYLPFSAGRRVCLAESLGKMQLFLFISRLLHKFRFS 420          

Query:  155 FLLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYER--------LIKKHGPVFGMKMG-LRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAG--IVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLN-LIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFL----MSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQS----FTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQ 1549
            FL +L    ALL NF+      +G+   P     P +G      F   +Y E         L K +G VF ++ G  +T+F  +  +A++  L+    +++GR   +  L GT      IVS DG    +HR+     +  +   T    + I  + T LL+  +  +      SD + + +A++I        F+   P+ +  + + +  I   +   Q     + +LD FP I  +L       T  KD +  I  +L+  +++ +KT+D      DL+   L  Q++LK+  E+ +       D  L+  L ++F+AGYETTST   W++ F+  Y E Q ++HQ++   +G +R+PT  DR  L    A + E+LRL +V+P A+ H T  DT +  Y +PKD++V+++  A H+DP  WE P  F P   L+ K   N     +    PF  G+R C GESL +++ F+F   +L +F+
Sbjct:   20 FLFVLF---ALLVNFVWGLYEFRGMPPGPRYTRLPVIG-----NFLNFDYREEDVRNMTKSLYKNYGRVFALQAGSFKTVFAASP-KAVKEVLVTRSGDYAGRPPFYSFLEGTLGGKDLIVSNDGPAWKLHRKLFTSALRRYLSDTPLLESRIADQTTKLLKYFKDRQHLPFDPSDQLRSCVADVICGITFGDMFNSSHPEFDRFLGDHVFLIEDAEHNAQ-----IALLDFFP-IAQYLPFKAYKITREKDEY--IFGVLRMLLDQGKKTYDDTQPARDLMTAIL--QERLKADAENEEQKQVLLADEYLLNQLGDMFIAGYETTSTSLRWAITFLVNYPEYQEEIHQQLDQVVGPDRMPTLADRPQLAIIQATIMEVLRLGNVVPNAIPHYTLKDTWLCGYRVPKDTIVIVDTMAVHLDPTCWENPTRFDPHRHLTEKGELNTS---QGNFLPFSAGRRVCAGESLAKVELFLFLSWMLHKFR 482          

Query:  311 RLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNK-DNFSGRWRLFQSLLGTRNA-GIVSTDGDQTHIHRRFIIRVMHE-FGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLP----ILDRFPRICDF-LMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQL-KSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVF 1648
            +L+K +G VF +++   +I  +N   A + A++    D+F+GR + F     TRN   I+  D  +    RR   +V H    M   R    I+ +  A    ++  +G  +   D     + NII  F+  KT+S+ DP+   IK            F      +P    IL+ FP +  F L S    K   N    +L +    H++TF   N   DL D  L  + ++ +  +++V   TD  ++  L ++F  G E+T +   W + F+  + E+QA+   E+ D IG E+ PT  DR+ L Y  AV+ E LR+ S +PLA+ H+   DT      IPK + VL+NL+A H DP  W  P EFYP  F++   NG  +   K    PF +G+R C+G+S+ + + F+    ++QR+  +F  P      +  L    G+ RY  I +F F
Sbjct:   34 KLVKDYGDVFTLRILGESIVFINSGAAAKEAMLGKHMDDFAGRPKKFTFDYITRNCQDIILGDYSRALNWRR---KVFHSALRMYAPRFDNIIREQIVAFESRMDASEGLPVDSRDEFALLILNIICSFVCGKTYSLDDPEFKKIKQ-----------FNIYSAEVPVATCILNIFPWLIHFPLKSSRLFKGFRNTRDEVLDKIFLAHKETFQEGNI-RDLADALLQAKIEIEREDKKAVGMVTDDHVIMMLSDIFGGGLESTISSLRWCVAFLIYHPEVQARAQAELDDVIG-EKFPTLADREKLPYIEAVIAETLRMGSNVPLAIPHKAIRDTAFRERAIPKGTTVLLNLWAIHRDPKEWSNPEEFYPGRFIN--SNGEFEVPSKLSFLPFSLGRRVCVGQSVAKAELFLIVARMIQRY--TFETP--RDTPRPCLEGVVGVTRY--IEDFKF 464          

Query:  263 VGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGT--RNAGIVSTD-GDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFN---KIHRILQQEIEEHRKTFDVKNEGEDLIDRFL-MKQD---QLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPL 1630
            +G L LL+  +   +  L K +G V+ + +G +   VL+   AI+ AL+    NF+GR  L   L     R  G+   D G+   + R+     +  +G   L+ +  I+ E   L   LE   G+   ++      + N+I   L    + + DP+   +  I  +++R        +    + + FP +   L     ++DL     + + IL+++ +EH KTFD +N   D  D  L  KQD   + KSS+E +Q  T   ++  L  LF+AG ETTST   W++ ++    ++Q ++H+EI D IG +  P  + RK+L    A   E LRL+++ PLA+ H+    + +  + IP+ + V  NL++ H DP VW+ P  F  + FL   E G  K        PFG G R C+GE L R + F+F   +LQRF+  F +P        ++  + G+V +P+
Sbjct:   37 IGNLNLLSKQMHLSFTELEKTYGKVYRLYLGHKLAIVLSG-DAIKEALVRQPRNFAGRPVLNPQLKSALNRGPGLTVMDYGETWKLFRKLGHSTIKVYGENRLQDV--IKDEVLELCNRLESSAGKPFDITQQSGIAVTNVICTKLFGTRYQIDDPEFLRVYEIHDKLSRIG------FGGNLVTNIFPSLASILPFSEKQRDLIQIGQERYEILERKYQEHVKTFDPENI-RDYTDALLKAKQDAEQEDKSSKEHLQEST--IIMAGLATLFIAGSETTSTTLGWAVIYLLHNPDVQERLHKEIDDVIGRDAFPQLSKRKELPVLEAFTAETLRLANLAPLAIPHKARERSTLQGFEIPEGTTVFANLWSLHHDPTVWKDPFTFNLDRFLD--EEGKFKAPVGGTFLPFGAGPRVCLGEVLARSELFLFLSRMLQRFE--FVNP--PGCELPSMEGDLGVVLHPM 484          

Query:  185 LLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLL--TFPILEY-YERLIKKHGPVFGMKM-GLRTIFVLNDYQAIRNALIDNKDNFSGR---WRLFQSLLGTRNAGIVSTDGDQTHI-HRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTR-----KDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLL-ELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTER--LPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQ 1549
            L   +  P  +P G       + +P +G  PLL  +F  L      L K +G V+ + + G R++ V +  +A R  L++ KD  +GR   + L     G++N  I  +D   T +  +R     M  +       + N   E  A ++ L+   G       ++     N++T       +++ DP+  L+  ++ +  R+         ++  LD FP    FLM    R     K +   ++    ++++ H  + D K+   DL D ++    + +  + SV      + +  ++ ++ + G ET+ST   W + +++ Y E+QA++HQ++ D IG ++  + T  DR  L Y  AV+ E +R+S+ +PLA+ H+ T DT +N YFIPKD+ V+ NL+  H+DP  W  P  F P  FL   E+G  K++  ++L PFG G+R C GE + +MQ F+    +L+  +
Sbjct:   18 LFHRYTEPSNLPPG------PRPYPLIGNTPLLIGSFSSLHVKLTELAKIYGSVYTLYLNGQRSVIVCS-AKAAREGLVERKDAIAGRPYSFTLDYVTNGSKN--ITFSDFCPTFLLKKRIAQSSMRRYYPQVEDKVNNQLEEVLARIKALD---GTAFDPHHLLSLVTLNLVTSMTFGTNYTLDDPEFLLLVQMIDDSTRS-------IGSMSTLDMFP----FLMHLPIRTSKLLKSITKTVNEYFMKQVQRHIDSNDGKSI-RDLTDGYIKGLTEAEKEDASVHEVNSIEHIAMVMADMIVPGSETSSTTMGWMIAYLAVYPEVQARLHQQLDDVIGRDKNTVITLKDRDRLPYVEAVIAETMRISTAVPLAIPHKATCDTTINGYFIPKDTTVIFNLWGVHLDPTEWADPHVFNPARFLD--EDG--KFIKSEKLLPFGAGRRVCPGEKIAKMQLFLMTSRLLRHLE 460          

Query:  239 PIEKGFPFVGILPLLTFPILEY-YERLIKKHGPVFGMKM-GLRTIFVLNDYQAIRNALIDNKDNFSGRWR--LFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFL-YFTLP-ILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYP 1627
            P  +  PF+G L  +   IL   ++    K+G VF + + G +T+ VLN  + ++ ALI   D+F  R +  LF  L+   N GIV T+G Q    RRF +  +  FG+G       IQ EC  + +   + +G+      ++ + ++NII   +  + F   D +   I   LTE+ + +  F  L Y   P ++ RFP     L +      L +KI   ++ +IEEH++  D     +D ID FL++ ++ +  +     F    L    L+LF AG ETT+T  +W L FM  Y +IQ +VH EI   IG+ R P+  D++++ YT AV+ EI R+  ++P+ +    + DT +++Y IPK ++++  L+    D +VWE P  F P+HFL+  ++G  K   ++   PFG GKR C+GE L RM+ F+FF S LQRF  S     T    +  L    G +R P
Sbjct:   42 PGPRSLPFIGDLHRIRPTILHLQFKEFAAKYGNVFSLNIFGGKTV-VLNGTKLLKEALIQKGDDFVDRPQIPLFSDLI--ENKGIVMTNGIQWKHQRRFALHTLRNFGLGKKTMEKYIQEECHYITQAFAEHQGKPFDAQPLLNSAVSNIICCLVFGERFEYSDKEYQQILQDLTEVVKLQGSFSALAYNVFPWLMKRFPGPLQKLFT------LVDKIMDFVKIKIEEHKENLDPACP-KDYIDSFLIEMEKNQGED---FGFDIKNLCACTLDLFGAGSETTTTTLYWGLLFMIHYPDIQEEVHAEIDAVIGSSRQPSMADKENMPYTDAVIHEIQRMGDIVPIGVARMASRDTMLDNYTIPKGTMIMPALHTVLHDESVWETPHSFNPQHFLN--QDGTFK--KREAFFPFGAGKRVCLGEQLARMELFLFFTSFLQRFSFS-----TAGGEKPPLEGRMGTIRSP 488          

Query:  308 ERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRW--RLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFN--KIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPL 1630
            E   K +GPVF +  G   + VL  Y+ ++NAL+++ + F  R    + Q L   +  G++ ++GD     RRF +  + +FGMG       I  EC  LLE  +K KG     +  +   ++NII   +    F   DPK   +      + RT    Q      P L  +  +        +R+++      +R   Q I  H K           +D FL+K   L+ S  +  +F D  L+  ++ LF AG ETTST   W L  M+KY +IQ +V  E+   IG +R+   +DRK+L +T AV+ EI RL+S++P AL H+T+ D     YFI K + V   L +   D N WEKP  FYP HFL    + + K+V ++   PF  G+R C+GESL RM+ F+FF ++LQ F   F  P   S+ + +L    GI   P+
Sbjct:   66 EEFSKTYGPVFTVFFGGEKVVVLAGYKTVKNALVNHDEEFGERAIPPIIQEL--NKGLGVLWSNGDIWRDIRRFALTNLRDFGMGKKACEDKITEECQYLLEVFKKFKGNAFDTTKPLNYAVSNIICSMVYGSRFEYDDPKFTSM------VDRTNRNIQLS--GSPTLQAYNMVPWLFKWVASRREVHECAAANRKQNQSIFSHLKETLNPQMCRGFVDAFLVKGQTLEKSGVTNSAFNDENLLMTVIHLFAAGTETTSTTLRWGLLLMAKYPKIQDQVQDELRRVIG-DRMVQVSDRKNLPFTDAVIHEIQRLASIVPTALPHKTSKDVTFQGYFIKKGTTVFPLLTSVLHDANEWEKPHTFYPAHFL----DKDGKFVKREAFIPFSAGRRICLGESLARMELFMFFTTLLQNF--CFTPPPGVSKEELSLTPCGGITVGPV 493          

Query:  299 EYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTK-DIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPV 1570
            E + +L  ++G ++ ++ G R   VLN ++A++ AL+   D+   R  L       +  G++ ++G      RRF +  +  FG G       I  E     E L++ KGE +    II   ++NII   +    F+ GD K   +  +     + +  I+  LY +  ++ R    C       T + ++ ++   + +E++EH+K++D  ++  D ID +L +  + K  E S  +F +  L+  +L+LF+AG ETTST   W+  +M+KY EIQ KV  EI   IG  R P   DR +L YT AV+ E+ R+ +++PL+L H T  D ++  + IPK  L++ NL +   D   WE P  F P HFL    N + K+V +    PF  GKR C+GE+L RM+ F+FF S +Q F  S    V
Sbjct:   87 ESFSKLAAEYGDLYSLRFGQRWTVVLNGHKALKEALVTKGDSVVDRPHLPLQDEIAKGLGVIFSNGANWTEQRRFALSTLRYFGFGKKSLEPVILNEFAHCAEELKRFKGEPLDPHLIINNTVSNIICHLVFGHRFNYGDKKFKKLMLLFDRALQIEASIWAQLYNSFTLIMR----C-LPGPHKTLQHIWREVQDFIGEELKEHKKSWD-PSDARDYIDFYLTEIQKTKGQEGS--TFDEENLIMCVLDLFVAGSETTSTTLRWAFLYMAKYPEIQEKVQAEIHKVIGKSRPPCMEDRAELPYTDAVIHEVQRIGNIVPLSLPHATNKDVQLGGFTIPKGVLIIPNLTSVLFDEKEWETPHAFNPGHFL----NKDGKFVKRGAFIPFSAGKRLCLGENLARMELFLFFTSFMQHFSFSMPAGV 499          

Query:  302 YYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGR------WRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTK-DIFQFLYFTLP-ILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPV 1570
            Y+ +L + +G VF ++ G  T   ++ Y+ ++ AL+   +NF  R       R +Q   G  N GI  ++G++    RRF +  +  FG+G       I  E   L   +E  KG+    + +    ++NI+ + +M K F   D   + +   L+E+ R +  ++  LY   P ++   P   + +      KD F+ +   L QEI+ H+K  D +N   D ID FL++ ++ ++S+     F +  L    L+LFLAG ETTST   W+L ++ K+ ++Q KV QEI   IG  RLP+  DR +L YT AV+ EI R  +++PL  +     DT +  YFIPK + ++  L +   D   WE P  F PEHFL    + + K+V K+   PF  GKR C+GE L RM+ F+F V +LQ+F  S  + V
Sbjct:   61 YFTKLAETYGNVFSVRFGSETSVFVSGYKMVKEALVTQAENFVDRPYSPMATRFYQ---GPTN-GIFMSNGEKWKKQRRFALSTLRTFGLGKNTMEQCICEEIRHLQAEIESEKGQLFTPTGLFNNAVSNIVCQLVMGKRFDYNDHDFHTMIKYLSEVLRLEGSVWGLLYEAFPGLMKHLPGPHNEMF-----KD-FDILRDFLDQEIKMHKKDLD-RNNPRDYIDSFLIEMEKHQNSD---LGFNEANLAFCSLDLFLAGTETTSTTLMWALIYLIKHPDVQVKVQQEIDRVIGQNRLPSMADRPNLPYTDAVIHEIQRFGNIVPLNGLRVAAKDTTLGGYFIPKGTALMPMLTSVLFDKTEWETPDTFNPEHFL----DADGKFVKKEAFLPFSAGKRVCLGEGLARMELFLFLVGLLQKFSFSVPEGV 473          

Query:  203 RPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEY-YERLIKKHGPVFGMKM-GLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLN-LIKNILTEIARTKDIFQFLYFTLP-ILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYP 1627
            RP+  P G   +P      F+G L  +    L   +    +K+G VF + + G RT+ +LN Y+ ++ AL+   D+F  R  +   +    N GIV ++G+     RRF +  +  FG+G     T IQ EC  + +     +G+      +I   ++NII   +  + F   D +   +++N+   +     +   LY   P ++ R P     + S T +   F KI      +I EH+  FD  +  ED ID FL+   +++ S++    F    +    ++LFLAG ETT+T  +W L +M  Y +IQ KVH EI   IG+ R P+  D++ + YT AV+ EI R+  ++P  +  +   DT ++ Y IPK ++++  L++   D ++W+ P  F P++FL    + + K+  ++  NPFG GKR C+GE L RM+ F+FF S+ QRF  SF+ P  E   Q +L +  G  R P
Sbjct:   36 RPKNFPPGPHSLP------FIGDLHRIQPARLHVQFTEFAEKYGNVFSLHLLGERTV-ILNGYKQVKEALVQQGDDFVDRPTIPLFVDTIDNKGIVMSNGNSWKQQRRFALHTLRNFGLGKKTMETYIQNECHYITQTFADKQGKPFDAQFLINNAVSNIICCLVFGERFEYSDQEYQKILRNLNDLLILEGSVSAMLYNMFPWLMKRLPGPHQKIFSLTRKIIDFVKI------KINEHKGNFD-PSAPEDYIDSFLI---EMEKSQDKDSGFDIDNMCICTMDLFLAGTETTTTTLYWGLLYMIYYPDIQEKVHAEIDAVIGSSRQPSMADKESMPYTDAVIHEIQRMGDIVPQGVFRQANRDTTLDKYTIPKGTIIVPALHSVLHDESMWDNPHSFDPKNFL----DKDGKFCKREAFNPFGAGKRVCLGEQLARMELFLFFTSLFQRF--SFSAPTGE---QLSLESRMGATRCP 488          

Query:  143 MIWFFLLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVFNRIQ 1660
            MIWFFLLILISVVALLFNFLRPRPIPKGLQKVPIEKGFP +GILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDY+AIRNALIDNKDNFSGRWRLFQSLLGT+NAGIVSTDGDQTHIHRRFII+VMHEFGMGTLRSLTNIQTECTALLECLEKC+GERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPR+CDFLMSFTTRKDLFNK+HRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESV+SFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQ+KVHQEI+DSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYP INEFVFNRIQ
Sbjct:    1 MIWFFLLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPLIGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYRAIRNALIDNKDNFSGRWRLFQSLLGTQNAGIVSTDGDQTHIHRRFIIKVMHEFGMGTLRSLTNIQTECTALLECLEKCQGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRVCDFLMSFTTRKDLFNKVHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVKSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQSKVHQEIIDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPSINEFVFNRIQ 506          

Query:  179 VALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVFNR 1654
            V + +  ++   I KGL+ +P EKG PFVG+L  +  PIL+YYERLIKKHG VF ++ G+R + +LNDYQ +++A +D+  N+SGRWRL  SLL   N+GI   DG      R F+++V+H+FGMG   S   ++ EC  LLE LE  +G+R+  SD+I  Y  NII+KF MNK FS GD KL  I +++T +A+ KD+ QF +F LPI D+ P +CD+++S T R   F+ +H+  Q+E++EHRK+ D+ +EGEDLIDRFL+KQ QLK+S  S++ FTDFQL+R  LEL +AG ETT+T   WS  FMSKY  IQ KVH+EI++ IG ER PT NDRKDL YT AVMDEI R+SSV PLAL+HR  ND+ +N Y++PKD+LV  NLYACH D  VWEKP+EFYPE FLS   NG+IKY   + LN FGMGKR+C GESL +M+ FIFF SI+QRF+V F++ V+++ ++EAL  N+G+VR   IN+F+F +
Sbjct:   13 VTIYWKLIKRTSISKGLKIIPTEKGLPFVGVLHQMETPILKYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLVSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNDGLVRCSKINKFIFTK 504          

Query:  143 MIWFFLLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVFNRIQ 1660
            MI  +L   +   A+ + F+R   IPK L+++P EKG P +G+L  +  PIL YYERLIKKHG VF ++ G+R + +LNDYQ +++A + +  N+SGRW++ QSL+ + NAGI   DG+     R F+++V H+FGMG   S   ++ EC  L++ LE   G+ + VSD+I  Y  NII+KF+MNK FS  + K   + ++     + KD FQFL++TLP+ D+   +CD+++  T R+  F+ + +++Q+E++EHRKT D+ +EGED IDRFL+KQ QLK+S  S + FTDFQL+R  +EL +AG ETT T   WS  FMSKY  IQ KVH EI+ ++G ER PT NDRK L YT AVMDE++R+SSV PLA +HR   D+ +N Y++PKDSLV  NLYAC+ D  VW+KP+EFYPEHFLS   NG I Y P + LNPFG+GKR+C+GESL RM+ F+FF SI+QRF+V FA+ V+E+ ++EAL  NEG+VR   I  F+F +++
Sbjct:    1 MIIIYLCTFLLGAAIYWKFIRLTSIPKELKRIPTEKGLPIIGVLHKIESPILRYYERLIKKHGSVFAVRFGMRDVIILNDYQTVKSAFVHDGSNYSGRWKVSQSLMMSGNAGIAFIDGEMWQTQRTFMLKVFHDFGMGKSVSYEIVRQECHFLIDELETLIGKCVDVSDLIQLYTVNIISKFIMNKRFSRKEDKYKRLSDLSQHALKQKDFFQFLFYTLPLFDKMNWLCDWILRRTNRRIPFDAVDKLVQEELDEHRKTLDLNSEGEDFIDRFLIKQHQLKTSTGSSEQFTDFQLLRLSMELLVAGLETTMTTLGWSFLFMSKYTNIQKKVHNEIIKTVGKERFPTLNDRKYLHYTQAVMDEVIRVSSVAPLAFVHRAMEDSSLNGYYVPKDSLVFSNLYACNFDEKVWKKPKEFYPEHFLSTDINGVIIYTPNESLNPFGVGKRRCVGESLARMEIFVFFTSIMQRFEVKFAEDVSEALYEEALIGNEGVVRSSKIKNFIFEKLE 506          

Query:  143 MIWFFLLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPLINEFVFNRIQ 1660
            MI  +L   +   A+ + F R  PIPKGL+++P EKG PFVG+L  +  PI  YYERLIKKHG VF ++ G+R + +LNDYQ +++A +D+  N+SGRW++ QSLL +  A I   DG+   I R F+++V H+FG+G   S    + EC  L++ LE   G+ + VSD+I  Y  NII+KF+ NK FS  + K   I N+  +  + KD  Q L++TLP+ D+   +CD+++  T RK LF+ + +++Q+EI+EHRKT D+ +EGEDLIDRFL+KQ QLK+S  S + FTDFQL R  LEL LAG ETT+T   WS  FMSKY  IQ KVH+EI++ IG ER PT ND+KDL YT AV+DEI R+SSV PLAL+HR  ND+ +N Y +PKDSLV  NLYACH D  VWEKP+EFYPE FLS   NG+IKY   D LNPFG+GKR+C GESL RM+ F+FF SI+QRF+V FA+ V+++ ++EAL  NEGIVR   I  ++F +++
Sbjct:    1 MIIIYLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQLRRLSLELLLAGLETTTTSLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTLNDKKDLHYTQAVIDEIFRVSSVGPLALVHRAMNDSSINGYHVPKDSLVYSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYKANDSLNPFGVGKRRCTGESLARMEIFVFFTSIMQRFEVRFAEDVSDALYEEALIGNEGIVRGSKIKNYIFTKLK 506          

Query:  236 VPIEKGFPFVGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYQAIRNALIDNKDNFSGRWRLFQSLLGTRNAGIVSTDGDQTHIHRRFIIRVMHEFGMGTLRSLTNIQTECTALLECLEKCKGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRICDFLMSFTTRKDLFNKIHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVQSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQAKVHQEILDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPL-INEFVFNR 1654
            +PIEKG P VG+L  L +P+L+YYE+L +KHGP+F M++G+R IFVLN+Y  IR A ++N +NF+GRW+LFQ+L+ T N+G+VS DGD  H+H+ F++ VMH+     + S  N Q EC  LLE LE    + I +S++I  Y  NII++F++NK F+  +P    +  +  E A   DIFQF++FTLPI D+ P IC  L+ FT R   F K   I Q+EIEEHRK  D+ +EGEDLID FL+KQ QLKS+  SV SFTD QL++  LELF+AG+ETTSTI  WS  FM++Y +IQ  V++EI+D IG ERLPT  DRK L YT AVMDE+ RLSS+ PLA+IHR  ND  ++ YFIPKDSLV  N++ CH DPNVWE+ +EFYP HFL     GNIKY PK +LN FG+GKRQCIGESL RM+YFIFF S++QRF V+FA  V E +F  A+R  +GI+R P+ + +++F R
Sbjct:    2 IPIEKGLPLVGVLLKLKYPVLDYYEKLARKHGPLFRMRIGMRDIFVLNNYDTIRKAFVENGNNFAGRWKLFQALVVTNNSGLVSIDGDLWHMHKAFVLNVMHK----CVTSFDNTQEECLCLLEELESLNKKVINLSEVIRVYTVNIISRFVLNKRFNRDNPIFTFLSKMSLEFAERADIFQFIFFTLPIFDKLPGICRLLIDFTDRGRKFRKAQNIFQEEIEEHRKRLDLDSEGEDLIDCFLIKQHQLKSTTGSVGSFTDIQLIQSSLELFIAGFETTSTILEWSFLFMARYNDIQENVYKEIVDKIGKERLPTMKDRKQLVYTQAVMDEVYRLSSISPLAIIHRVVNDCNIDGYFIPKDSLVQSNIWGCHTDPNVWERHKEFYPHHFLKTDAAGNIKYDPKQELNAFGIGKRQCIGESLARMEYFIFFTSVMQRFHVNFAKSVNEIEFDSAIRGCDGIIRSPVSLKDYIFTR 471