GCR070

Overview
NameGCR070
Smed IDSMED30003601
Length (bp)1235
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of GCR070 (SMED30003601) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for GCR070 (SMED30003601) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003601

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30003601h1SMcG0011711 SmedASXL_007504SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30003601h1SMcG0011711 dd_Smed_v4_17025_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30003601h1SMcG0011711 dd_Smed_v4_17025_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30003601h1SMcG0011711 dd_Smed_v4_17025_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30003601h1SMcG0011711 dd_Smed_v6_17025_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of GCR070 vs. Ensembl Human
Match: GPR139 (G protein-coupled receptor 139 [Source:HGNC Symbol;Acc:HGNC:19995])

HSP 1 Score: 57.3806 bits (137), Expect = 1.802e-8
Identity = 54/230 (23.48%), Postives = 93/230 (40.43%), Query Frame = 1 
Query:  448 WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYG------PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSI-----LQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFR---ENLRKMFFKTNRDQDLLNRQKNFN 1095
            WI V + +DR+I V +P + H  +   R + V  S+    F+ +IP +W +   W +                  Y+   +  +LI I+       P  +  + NS++   L R  N R        +   +G+  T +L  +  +F     P  I     L     +N ++  I+  I + L +LN++INF +Y    +RFR       K FFK  +         NF+
Sbjct:  117 WITVPLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYW-WPNIWTE-----------------DYISTSVHHVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRL-------RGYSTGK-TTAILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATLKAFFKCQKQPVQFYTNHNFS 320
[Close]
BLAST of GCR070 vs. Ensembl Celegans
Match: frpr-8 (FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q20686])

HSP 1 Score: 71.633 bits (174), Expect = 2.382e-13
Identity = 63/266 (23.68%), Postives = 118/266 (44.36%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYL--GNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRE 1026
            +V  +   RSS+NV L  L+V+D++ L  S+      +G ++            + S  W L   N+ + G  W  V+V +DRF+ V  P  +    T  RA  +  +I   + ++  P F++         C  +       + ++K  Y     ++ ++  P  ++I+ N  +  ++ +A  +R+S+   +N      +  T M I ++  FL   + +++     T          PI + L  LNS+ N VIYS+ G RFR+
Sbjct:   67 VVFTRKQMRSSLNVYLAGLSVFDLILLSFSALIFSPLQGCVLQGHGDTAVCHFFWRSTPWTLPISNIAQCGSVWTCVAVTVDRFLAVNYPLHSKIWCTPRRATTILIAITVFSILFKAPMFFELT----NDDCGRLRTSFLRDNKYYKEYYVTFGYLIALLLIPWTVMIILNVFVVKAVHKAYKIRRSMQGGKNNQEEKDRRCTLMAIAMVLTFLIFNVVAAVNNLAETVFEVSLGFWSPIGNLLICLNSASNIVIYSLFGARFRQ 328
[Close]
BLAST of GCR070 vs. Ensembl Celegans
Match: frpr-3 (FMRFamide Peptide Receptor family; VRFamide receptor 1 [Source:UniProtKB/TrEMBL;Acc:G5EG36])

HSP 1 Score: 63.929 bits (154), Expect = 4.755e-11
Identity = 74/282 (26.24%), Postives = 131/282 (46.45%), Query Frame = 1 
Query:  244 KKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRN---WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWD----KRTCKWIII----MNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQ--AITTKNCF---IYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKM 1041
            +K +++ S+NVLL  L++ D+   +L+    VFA         ++P      I +  YL  VT   ++   W+ VS+ +DR++ V +PF  +   T  RA I    +   +  YN+ R W+Y   +D     RT + +++     NP+   +++ V  ++ Q       P+ +L V N  +  +++ A   R+ L+A   +   +     KM+I+V+ VFL   + S IL    I  K  F   I   +  I + L ++NS+   V Y     RFR   R +
Sbjct:   33 RKTFRKKSINVLLAALSMSDLCVCVLA--IPVFAST---QLQQVIPPTITAMIMV--YLYPVTIMFQSVSVWLLVSITIDRYLAVCHPFMVNTYCTRNRALITVGVVVIFSVAYNLIRIWEYTINFDVAPENRTIEDLVVPKLRANPHFLLWYQNVATLVSQFAF----PLTVLCVLNIQVARTIIEASEQRRELVASVKREHSTA----KMMIMVVLVFLVCYIFSFILNIWEILDKETFGGDIGWFMNDINNVLIVVNSTSAIVFYYKYSTRFRNQARTL 299
[Close]
BLAST of GCR070 vs. Ensembl Celegans
Match: frpr-7 (FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q94219])

HSP 1 Score: 63.1586 bits (152), Expect = 1.269e-10
Identity = 58/255 (22.75%), Postives = 120/255 (47.06%), Query Frame = 1 
Query:  358 IYFSHLLPELSKNFI-SLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAK----AWDKRTCKWIIIMNPNLSN-FHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMA---------------KQNQARPSGQMETKMLIVVIGVFLFTE-LPS--SILQAITTKNCF----IYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRK 1038
            +++ HL+ + +  ++    +   N T  G  WI +++ +DR++ +  P +        R + +   ++    +++IPRF++         D+ +C   I       N  +  +Y++IL M+ +   P ++L      +TI+L  A   R+SL A               + N +R   +    ML++VI  FL ++ LP+   +L+ +  ++ F    +  + + I + L +LN S NF ++ + G+RFR + RK
Sbjct:   93 LWWGHLVSQGTYVYLYPYVYTFANTTHTGSVWIVLTLTIDRYLALCQPLKHRAIGKKRRVRRLMIVVSAMAVMFSIPRFFEVHVILICDEDQLSCVATIDRTELFDNRLYWTIYHVILAMVFVTLLPCLILFALTLRITIALRSAIAKRKSLCAPNSDIDTRCKSIKSSRYNSSRKDHKSNI-MLVLVIAKFLVSDILPTVIDVLEHVVGQSAFMRSPLASLFVDISNFLIVLNCSSNFWVFFVWGKRFRRSCRK 346
[Close]
BLAST of GCR070 vs. Ensembl Celegans
Match: dmsr-8 (DroMyoSuppressin Receptor related [Source:UniProtKB/TrEMBL;Acc:Q18475])

HSP 1 Score: 62.3882 bits (150), Expect = 2.330e-10
Identity = 79/313 (25.24%), Postives = 145/313 (46.33%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLF----LLLSSYYIVFA------RGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSAS----IAFATFV----YNIP------------RFWDYAKAWDKRTCKWII-IMNPN----LSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAK-QNQARPSGQMETKMLIVVIGVFLFTELPSSILQ---AITTKNCF---IYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFF 1047
            +VL +   RS++N LLC +A+ D+L     L+  +++++FA          IY+++ L   S+   ++ ++  ++      W+ V +A  R   +R       R TS   + V+      IA  TF+     N+P              W   KA +      ++ ++ P+    L N   +   ++ +++        LL+ F+ +  +S++R    R+  +A+  N+ R      T ML+ V+ +FLF ELP  +L    AI TK  F   IY  L  + D L++LNS++NF+IY    ++FR    ++F 
Sbjct:   51 IVLTRPSMRSAVNSLLCAIALCDILVMTSVLVFVTHFLLFAGYRCDPTDYNIYWAYFLYYHSQA--TVIFHATSI------WLTVLLAQIRVFSIR-------RATSVAGESVTNQMTCIIAVTTFIVVCLLNVPNMLTFEIIETPASLWLQCKANETAEDDMLVYLVAPSDHCGLLNIAFWTNGVLFKVV------PCLLLTFSIVALVSIIRDVGKRRKQLAQVMNKKRMPRDHTTPMLVAVLSIFLFAELPQGVLHVFNAIFTKETFYDKIYIHLGDVMDVLSLLNSAVNFIIYCAMSRKFRAVFIQIFL 342
[Close]
BLAST of GCR070 vs. Ensembl Celegans
Match: dmsr-6 (DroMyoSuppressin Receptor related [Source:UniProtKB/TrEMBL;Acc:G5EGR5])

HSP 1 Score: 61.6178 bits (148), Expect = 3.277e-10
Identity = 35/110 (31.82%), Postives = 63/110 (57.27%), Query Frame = 1 
Query:  718 PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAI-----TTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENL 1032
            P +LL+ F   L I+ +R  N ++ ++ K+ +A+  G   T ML++++ VFLFTELP  I+  +     T  +  +Y  L  + D L+++N  + F++YS    R+R+ L
Sbjct:  221 PCLLLLTFTIAL-INRLRENNEKRKILIKEERAKKRGDFTTYMLLLMVTVFLFTELPQGIMAILNALFTTQFHQMVYLNLADVLDLLSLINCYVAFLVYSFTSSRYRQTL 329
[Close]
BLAST of GCR070 vs. Ensembl Fly
Match: FMRFaR (gene:FBgn0035385 transcript:FBtr0340706)

HSP 1 Score: 74.7146 bits (182), Expect = 3.307e-14
Identity = 82/300 (27.33%), Postives = 142/300 (47.33%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSK--NFISLTWY-LGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIII--MNPNLSNFHKYVYNIILQMLIMIYG---PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKT--NRDQ-DLLNRQKNFNTN 1101
            ++L +   RSS+N LL  LA  D + L+++S  +     I  Y  H     +    FIS   + +G + +    ++  +V L+R++ V +P +A    T  RA+I        +  YN+PRFW+          K +I+  + P+     +   NI +    +I     P + L + N L+   + RA   RQ L   +++ R  G + T +L VVI  F+   LP  +L         I   +  I + L  +NSS+NF+IY + G++F+     +FFK   +RDQ DL++ + + + N
Sbjct:  136 IILSRPQMRSSINYLLTGLARCDTV-LIITSILLFGIPSIYPYTGHFFGYYNYVYPFISPAVFPIGMIAQTASIYMTFTVTLERYVAVCHPLKARALCTYGRAKIYFIVCVCFSLAYNMPRFWEVLTVTYPEPGKDVILHCVRPSRLRRSETYINIYIHWCYLIVNYIIPFLTLAILNCLIYRQVKRANRERQRL--SRSEKREIG-LATMLLCVVIVFFMLNFLP-LVLNISEAFYSTIDHKITKISNLLITINSSVNFLIYIIFGEKFKRIFLLIFFKRRLSRDQPDLIHYESSISNN 430
[Close]
BLAST of GCR070 vs. Ensembl Fly
Match: FMRFaR (gene:FBgn0035385 transcript:FBtr0332085)

HSP 1 Score: 74.7146 bits (182), Expect = 3.307e-14
Identity = 82/300 (27.33%), Postives = 142/300 (47.33%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSK--NFISLTWY-LGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIII--MNPNLSNFHKYVYNIILQMLIMIYG---PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKT--NRDQ-DLLNRQKNFNTN 1101
            ++L +   RSS+N LL  LA  D + L+++S  +     I  Y  H     +    FIS   + +G + +    ++  +V L+R++ V +P +A    T  RA+I        +  YN+PRFW+          K +I+  + P+     +   NI +    +I     P + L + N L+   + RA   RQ L   +++ R  G + T +L VVI  F+   LP  +L         I   +  I + L  +NSS+NF+IY + G++F+     +FFK   +RDQ DL++ + + + N
Sbjct:  136 IILSRPQMRSSINYLLTGLARCDTV-LIITSILLFGIPSIYPYTGHFFGYYNYVYPFISPAVFPIGMIAQTASIYMTFTVTLERYVAVCHPLKARALCTYGRAKIYFIVCVCFSLAYNMPRFWEVLTVTYPEPGKDVILHCVRPSRLRRSETYINIYIHWCYLIVNYIIPFLTLAILNCLIYRQVKRANRERQRL--SRSEKREIG-LATMLLCVVIVFFMLNFLP-LVLNISEAFYSTIDHKITKISNLLITINSSVNFLIYIIFGEKFKRIFLLIFFKRRLSRDQPDLIHYESSISNN 430
[Close]
BLAST of GCR070 vs. Ensembl Fly
Match: FMRFaR (gene:FBgn0035385 transcript:FBtr0072980)

HSP 1 Score: 74.7146 bits (182), Expect = 3.307e-14
Identity = 82/300 (27.33%), Postives = 142/300 (47.33%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSK--NFISLTWY-LGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIII--MNPNLSNFHKYVYNIILQMLIMIYG---PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKT--NRDQ-DLLNRQKNFNTN 1101
            ++L +   RSS+N LL  LA  D + L+++S  +     I  Y  H     +    FIS   + +G + +    ++  +V L+R++ V +P +A    T  RA+I        +  YN+PRFW+          K +I+  + P+     +   NI +    +I     P + L + N L+   + RA   RQ L   +++ R  G + T +L VVI  F+   LP  +L         I   +  I + L  +NSS+NF+IY + G++F+     +FFK   +RDQ DL++ + + + N
Sbjct:  136 IILSRPQMRSSINYLLTGLARCDTV-LIITSILLFGIPSIYPYTGHFFGYYNYVYPFISPAVFPIGMIAQTASIYMTFTVTLERYVAVCHPLKARALCTYGRAKIYFIVCVCFSLAYNMPRFWEVLTVTYPEPGKDVILHCVRPSRLRRSETYINIYIHWCYLIVNYIIPFLTLAILNCLIYRQVKRANRERQRL--SRSEKREIG-LATMLLCVVIVFFMLNFLP-LVLNISEAFYSTIDHKITKISNLLITINSSVNFLIYIIFGEKFKRIFLLIFFKRRLSRDQPDLIHYESSISNN 430
[Close]
BLAST of GCR070 vs. Ensembl Fly
Match: SPR (gene:FBgn0029768 transcript:FBtr0344824)

HSP 1 Score: 64.6994 bits (156), Expect = 4.630e-11
Identity = 64/250 (25.60%), Postives = 119/250 (47.60%), Query Frame = 1 
Query:  448 WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAK-----AWDK--------RTCKWI-IIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQME-----TKMLIVVIGVFLFTELPSSILQAITTKNCFIYRI----LIPICDGLT----ILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVTIVS 1116
            W+ +++A+ R+I V +   A    T  R +  +A IA   F++ +PRF+D         W+          T  W+   +  +L     Y++ ++   L+    P I+L+  N LL  ++ +A+  R+ L+ ++N+ +   ++      T MLIVV+ VFL  E+P +++ A+   +  I       L  IC  LT    + +  INF IY    ++FRE  +++F         L  +K+ +T  +IV+
Sbjct:  184 WLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRFFDRTYMPLVIEWNGSPTEVCHLETSMWVHDYIGVDLYYTSYYLFRVLFVHLL----PCIILVTLNILLFAAMRQAQE-RRKLLFRENRKKECKKLRETNCTTLMLIVVVSVFLLAEIPIAVVTAMHIVSSLIIEFLDYGLANICIMLTNFFLVFSYPINFGIYCGMSRQFRETFKEIFLGR------LMAKKDSSTKYSIVN 422
[Close]
BLAST of GCR070 vs. Ensembl Fly
Match: SPR (gene:FBgn0029768 transcript:FBtr0339781)

HSP 1 Score: 64.6994 bits (156), Expect = 4.630e-11
Identity = 64/250 (25.60%), Postives = 119/250 (47.60%), Query Frame = 1 
Query:  448 WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAK-----AWDK--------RTCKWI-IIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQME-----TKMLIVVIGVFLFTELPSSILQAITTKNCFIYRI----LIPICDGLT----ILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVTIVS 1116
            W+ +++A+ R+I V +   A    T  R +  +A IA   F++ +PRF+D         W+          T  W+   +  +L     Y++ ++   L+    P I+L+  N LL  ++ +A+  R+ L+ ++N+ +   ++      T MLIVV+ VFL  E+P +++ A+   +  I       L  IC  LT    + +  INF IY    ++FRE  +++F         L  +K+ +T  +IV+
Sbjct:  184 WLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRFFDRTYMPLVIEWNGSPTEVCHLETSMWVHDYIGVDLYYTSYYLFRVLFVHLL----PCIILVTLNILLFAAMRQAQE-RRKLLFRENRKKECKKLRETNCTTLMLIVVVSVFLLAEIPIAVVTAMHIVSSLIIEFLDYGLANICIMLTNFFLVFSYPINFGIYCGMSRQFRETFKEIFLGR------LMAKKDSSTKYSIVN 422
[Close]
BLAST of GCR070 vs. Ensembl Zebrafish
Match: oprd1a (opioid receptor, delta 1a [Source:ZFIN;Acc:ZDB-GENE-990415-199])

HSP 1 Score: 54.299 bits (129), Expect = 1.409e-7
Identity = 50/216 (23.15%), Postives = 101/216 (46.76%), Query Frame = 1 
Query:  466 ALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSI------LQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRK--MFFKTNRDQDLLNRQKN 1089
            ++DR+I V +P RA +  T  +A+I++  I   +    +P           +     ++  P+      + ++ + ++ + I+  ++ ++V      + ++R K+VR  L++   +   + +  T+M++VV+  F+    P  I      L  I  KN F+      +C  L   NSS+N V+Y+   + F+   R   + F+T  DQ  LNR +N
Sbjct:  147 SVDRYIAVCHPVRALEFRTPIKAKIINVCIWILSSAVGVPIMIMAVTRVTNQNTTVCMLKFPD----PDWYWDTVTKICVFIFAFVVPVLVITICYGLMILRLKSVR--LLSGSKEKDRNMRRITRMVLVVVAAFIICWTPIHIFIIVKTLVDINQKNPFVIASW-HLCIALGYTNSSLNPVLYAFLDENFKRCFRDFCLPFRTRADQSNLNRARN 355
[Close]
BLAST of GCR070 vs. Ensembl Zebrafish
Match: gpr139 (G protein-coupled receptor 139 [Source:NCBI gene;Acc:798482])

HSP 1 Score: 51.9878 bits (123), Expect = 6.959e-7
Identity = 70/298 (23.49%), Postives = 126/298 (42.28%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSIL--------QAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRE---NLRKMFFKTNRDQDLLNRQKNFN 1095
            LVL++  ++SS N LL  LAV D+L LLL    IVF   ++  F  L   L  +       L   + +   WI V + +DR+I V +P R H  +   R + V  ++     + ++P +W + + W       +   +P   +     + ++      +Y  ++   VF SL  I +VR    R+S    +     S    T +L+ +  VF     P +++        Q        +  ++  + + L +LN+ +NF +Y    +RFR     + K FF+  +         NF+
Sbjct:   53 LVLRR--QKSSYNYLL-ALAVADILVLLL----IVFVDFLLEDFI-LGAPLPHSLNKAVQVLEFSSIHTSIWITVPLTIDRYIAVCHPLRYHTVSYPARTRKVILAVYAGCLISSVPYYW-WPELWHG-----LPGASPGGRSSSAGQHVLVWVHCATVY--LLPCSVFFSLNAI-IVRKLRCRRSCFRLRGY---STGKTTAILLAITSVFAVLWAPRTLMILYHLYTVQPAMPGPARLLHLVTDVANMLALLNTGVNFFLYCFISKRFRRMAGTVLKAFFRCRKQPPPFYASHNFS 330
[Close]
BLAST of GCR070 vs. Ensembl Zebrafish
Match: trhr2 (thyrotropin releasing hormone receptor 2 [Source:ZFIN;Acc:ZDB-GENE-050419-193])

HSP 1 Score: 51.9878 bits (123), Expect = 7.811e-7
Identity = 92/382 (24.08%), Postives = 151/382 (39.53%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIA-----------VSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFW----DYAKAWDKRT-CKWIIIMNPNLSNF---HKYVYNIILQMLIMIYGPMILLIVFNSLL---TISLVRAKNVRQSLMAKQN------QARPSGQME-----TKMLIVVIGVFLFTELPSSILQAITT--KNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDL-------------LNRQKNFNTNVTIVSMKKQNNV-DSKDDNFSF----DNTEN*ICDFMINIIIPSV 1221
            +VL     R+  N  L +LAV D++ L+ +                 LP +S++ ++ TW  G+    G  +              +  ++R+I + +P RA    T  RA+ + A +   T VY +   W    D     D R  C + +  +  L  +       Y I L + I +YG +  ++  N L        V A  +R+S     +      Q RP   +      TKML VV+ +F    +P   L  I +     ++    I  C      NS+IN V+Y++  Q+FR   R ++    R +DL             L R     +N T  + KK  +V   +  N  F    +NT+  I D + N I PS+
Sbjct:   55 VVLTTRHMRTPTNCYLVSLAVADLMVLVAAG----------------LPNISESLMA-TWVYGHAGCLGITYFQYLGINASSCSITAFTVERYIAICHPMRAQTVCTVSRAKRIIAVVWVFTCVYCM--LWLFLVDIQVNPDGRVQCGYRVSRDLYLPIYLIDFTIFYVIPLLLAIALYGLIARILYLNPLPHPPDSGTVIAPTLRRSCKEPADGGKAIRQGRPKSALSSRKQVTKMLAVVVVLFALLWMPYRTLVLINSFVSTPYLDSWFILFCRTCIYANSAINPVVYNLMSQKFRSAFRGLY--RCRREDLHQRTLSMLQSGYSLGRDPRICSNGTRDTPKKVGSVTPEQKQNKGFENKVENTDRQISDGVENEINPSI 415
[Close]
BLAST of GCR070 vs. Ensembl Zebrafish
Match: trhr2 (thyrotropin releasing hormone receptor 2 [Source:ZFIN;Acc:ZDB-GENE-050419-193])

HSP 1 Score: 51.9878 bits (123), Expect = 8.464e-7
Identity = 92/382 (24.08%), Postives = 151/382 (39.53%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIA-----------VSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFW----DYAKAWDKRT-CKWIIIMNPNLSNF---HKYVYNIILQMLIMIYGPMILLIVFNSLL---TISLVRAKNVRQSLMAKQN------QARPSGQME-----TKMLIVVIGVFLFTELPSSILQAITT--KNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDL-------------LNRQKNFNTNVTIVSMKKQNNV-DSKDDNFSF----DNTEN*ICDFMINIIIPSV 1221
            +VL     R+  N  L +LAV D++ L+ +                 LP +S++ ++ TW  G+    G  +              +  ++R+I + +P RA    T  RA+ + A +   T VY +   W    D     D R  C + +  +  L  +       Y I L + I +YG +  ++  N L        V A  +R+S     +      Q RP   +      TKML VV+ +F    +P   L  I +     ++    I  C      NS+IN V+Y++  Q+FR   R ++    R +DL             L R     +N T  + KK  +V   +  N  F    +NT+  I D + N I PS+
Sbjct:   56 VVLTTRHMRTPTNCYLVSLAVADLMVLVAAG----------------LPNISESLMA-TWVYGHAGCLGITYFQYLGINASSCSITAFTVERYIAICHPMRAQTVCTVSRAKRIIAVVWVFTCVYCM--LWLFLVDIQVNPDGRVQCGYRVSRDLYLPIYLIDFTIFYVIPLLLAIALYGLIARILYLNPLPHPPDSGTVIAPTLRRSCKEPADGGKAIRQGRPKSALSSRKQVTKMLAVVVVLFALLWMPYRTLVLINSFVSTPYLDSWFILFCRTCIYANSAINPVVYNLMSQKFRSAFRGLY--RCRREDLHQRTLSMLQSGYSLGRDPRICSNGTRDTPKKVGSVTPEQKQNKGFENKVENTDRQISDGVENEINPSI 416
[Close]
BLAST of GCR070 vs. Ensembl Zebrafish
Match: gpr142 (G protein-coupled receptor 142 [Source:ZFIN;Acc:ZDB-GENE-130603-30])

HSP 1 Score: 50.0618 bits (118), Expect = 2.954e-6
Identity = 66/290 (22.76%), Postives = 123/290 (42.41%), Query Frame = 1 
Query:  316 LLSSYYIVFARGIII---YFSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLM---AKQNQARPS--GQMETKMLIVVIGVFLFTELPSS-----ILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFF----KTNRDQDLLNRQKNFNTNVTIVSMKKQNN 1134
            +LS  +I+F  G ++    F   +P L    +S+  +  N   +   W  V + +DR++ + +P    Q +   RA+ + A +        +P FW     W      W +   PN  N    +  I   + I+ + P  + +V NSL+ + L   K  RQ +    + Q  A PS  G+  T ML+ V  VF     P +      L   +  N +   +   + + L +LN+++NF +Y    + FR  +R +        +  + L N++   N + + +S  K++ 
Sbjct:   76 ILSQLFIIFV-GFLLETAVFHRDVPVLLLRSVSMMEFSAN---HASIWATVPLTVDRYVALCHPLLHRQISYPARARRIIAVVLTLALASGVPFFW-----WSD---MWRVSHEPN--NLDTAL--IWTHVTIIYFLPCCIFLVLNSLIILRL--RKRQRQQMCQDESGQQLAVPSRLGK-TTAMLLAVTSVFAVLWAPRTGVVLYHLYVTSVHNDWRVHLAYDLANMLAMLNTAVNFFLYCFVSKPFRAAVRDVLLFRGAPLHPRRPLRNQRTPANASTSSISSTKRSQ 346
[Close]
BLAST of GCR070 vs. Ensembl Xenopus
Match: gpr139 (G protein-coupled receptor 139 [Source:NCBI gene;Acc:100493863])

HSP 1 Score: 57.3806 bits (137), Expect = 1.899e-8
Identity = 74/300 (24.67%), Postives = 126/300 (42.00%), Query Frame = 1 
Query:  256 KRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYF--SHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYG------PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSI-----LQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFR---ENLRKMFFKTNRDQDLLNRQKNFNTNVT 1107
            ++SS N LL  LA  D++ L    ++IVF   ++  F  +  +P++    I +   L   + +   WI V + +DR+I V +P   H  +   R + V  S+    F+ +IP +W     W            PN+     Y    +  +LI I+       P  +  V NS++   L R  N R        +   +G+  T +L  +  +F     P  I     L      N ++  I+  I + L +LN++INF +Y    +RFR       K FFK  +    +    N+N ++T
Sbjct:   54 QKSSYNYLL-ALAAADIMVL----FFIVFVDFLLEDFILNKQMPQMLDKIIEV---LEFSSIHTSIWITVPLTIDRYIAVCHPLTYHTVSFPARTRKVIVSVYITCFLTSIPYYW-----W------------PNIW-IEDYTSTSVHHILIWIHCFTVYLVPCSIFFVLNSIIVYKLQRKSNFRL-------RGYSTGK-TTAILFSITSIFAILWAPRIIMILYHLYVSPIHNSWLVHIVTDIANMLALLNTAINFFLYCFISKRFRTMAAGTLKAFFKCQKQP--VQFYTNYNFSIT 317
[Close]
BLAST of GCR070 vs. Ensembl Xenopus
Match: crybg1 (crystallin beta-gamma domain containing 1 [Source:Xenbase;Acc:XB-GENE-989534])

HSP 1 Score: 50.0618 bits (118), Expect = 3.458e-6
Identity = 60/277 (21.66%), Postives = 125/277 (45.13%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVF-ARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYG-PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELP--SSILQAITTKNCFIYRIL---IPICDGLTILNSSINFVIYSMCGQRFRENLRKMF 1044
            L L+ D K S   + +  LAV D++FL    ++  + A G    F  ++ ++S + + L  +          +    +++DR++ V  PF + QR T ++A +VS S+     + ++P F+     +  R    +  M+     +  +   + L  + + +  P+ ++     ++ I L R+K     ++  QN+ R    +   ++  +I  F F  L    ++++     +C I   +   +P C  +   NS IN ++Y   G +FRE+ R +F
Sbjct:   53 LCLQGDLK-SVAKIYIVNLAVADLVFLATLPFWATYYALGYNWLFGKVMCKISSSLLCLNLF-------ASIFFISCMSVDRYVAVVYPFSS-QRRTKYQACLVSISVWILAILSSVPTFYFRNAFYINRLGAHVCAMDFPKEKYSSWCVGMSLMKIFLGFCVPVSVIATCYLMIGIHLKRSKG---PVINIQNRDRVQKIVTAIVMAFLICWFPFHALTFLDALVRMDIISHCKIVTFIEKAMPFCICMGFSNSCINPLLYCFVGNQFREHFRHLF 317
[Close]
BLAST of GCR070 vs. Ensembl Xenopus
Match: GPR142 (G protein-coupled receptor 142 [Source:HGNC Symbol;Acc:HGNC:20088])

HSP 1 Score: 50.0618 bits (118), Expect = 3.752e-6
Identity = 63/272 (23.16%), Postives = 127/272 (46.69%), Query Frame = 1 
Query:  256 KRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAW-DKRTCKWIIIMNPNLSNFHKYVYNIILQ---MLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAI-----TTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMF 1044
            K+SS + LL  L + D+L    S  +I+F  G I+  + L  ++    I +   L   + +   W+ V + +DR++ +  P +    +   R + V   +  ++FV  +P +W ++  W D RT        P L        ++IL+     I+ + P  + ++ NS++   L      R+   +K+ Q R +G+  T +L+ +  VF     P +I+  I     +    +   + + I + L +LN+++NF +Y    +RFR+ +R++ 
Sbjct:   63 KKSSYSYLL-ALTISDIL----SQIFIIFV-GFILQTAILHRKVPSTLIHVVSVLEFSSNHASIWVTVILTVDRYVALCYPLQYRSFSYPERTRRVIVFVFLSSFVTGVPFYW-WSDVWRDPRT--------PGL-------LDLILKWTHCFIIYFIPCTIFLITNSVIIYRL------RKRTGSKKCQLR-NGK-TTAILLGITSVFAVLWAPRTIVIIIHMYVSSVNKDWKVHLAMDIGNMLALLNTAVNFFLYCFVNRRFRDTVREIL 304
[Close]
BLAST of GCR070 vs. Ensembl Mouse
Match: Gpr139 (G protein-coupled receptor 139 [Source:MGI Symbol;Acc:MGI:2685341])

HSP 1 Score: 54.299 bits (129), Expect = 1.158e-7
Identity = 51/230 (22.17%), Postives = 93/230 (40.43%), Query Frame = 1 
Query:  448 WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYG------PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSI-----LQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFR---ENLRKMFFKTNRDQDLLNRQKNFN 1095
            WI V + +DR+I V +P + H  +   R + V  S+    F+ +IP +W +   W +                  Y+   +  +L+ I+       P  +  + NS++   L R  N R        +   +G+  T +L  +  +F     P  I     L     +N ++  I++ + + L +LN++INF +Y    +RFR       K  FK  +         NF+
Sbjct:  109 WITVPLTVDRYIAVCHPLKYHTVSYPARTRKVILSVYITCFLTSIPYYW-WPNIWTE-----------------DYISTSMHHVLVWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRL-------RGYSTGK-TTAILFTITSIFATLWAPRIIMILYHLYGAPIQNPWLVHIMLDVANMLALLNTAINFFLYCFISKRFRTMAAATLKALFKCQKQPVQFYTNHNFS 312
[Close]
BLAST of GCR070 vs. Ensembl Mouse
Match: Cxcr6 (chemokine (C-X-C motif) receptor 6 [Source:MGI Symbol;Acc:MGI:1934582])

HSP 1 Score: 48.521 bits (114), Expect = 8.149e-6
Identity = 41/201 (20.40%), Postives = 96/201 (47.76%), Query Frame = 1 
Query:  463 VALDRFIMVRNPFRAHQRNTSFR--AQIVSASIAFATFVYNIPRF-WDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRI-----LIPICDGLTILNSSINFVIYSMCGQRFRENLRKM 1041
            + +DRFI+V    +A  R   ++   Q++   I   + + ++P+  + + +  DK  C++    +  +S        +++QM +  + P++ +I+  S +  +L+ A+N ++                 K++ +V+ VFL T+ P ++   I + +   Y I      I + + +    + +N V+Y+  G +FR+N+ K+
Sbjct:  132 ITVDRFIVVVQATKAFNRQAKWKIWGQVICLLIWVVSLLVSLPQIIYGHVQDIDKLICQY---HSEEISTM-----VLVIQMTLGFFLPLLTMILCYSGIIKTLLHARNFQK-------------HKSLKIIFLVVAVFLLTQTPFNLAMLIQSTSWEYYTITSFKYAIVVTEAIAYFRACLNPVLYAFVGLKFRKNVWKL 311
[Close]
BLAST of GCR070 vs. Ensembl Mouse
Match: Cxcr6 (chemokine (C-X-C motif) receptor 6 [Source:MGI Symbol;Acc:MGI:1934582])

HSP 1 Score: 48.521 bits (114), Expect = 9.739e-6
Identity = 41/201 (20.40%), Postives = 96/201 (47.76%), Query Frame = 1 
Query:  463 VALDRFIMVRNPFRAHQRNTSFR--AQIVSASIAFATFVYNIPRF-WDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRI-----LIPICDGLTILNSSINFVIYSMCGQRFRENLRKM 1041
            + +DRFI+V    +A  R   ++   Q++   I   + + ++P+  + + +  DK  C++    +  +S        +++QM +  + P++ +I+  S +  +L+ A+N ++                 K++ +V+ VFL T+ P ++   I + +   Y I      I + + +    + +N V+Y+  G +FR+N+ K+
Sbjct:  139 ITVDRFIVVVQATKAFNRQAKWKIWGQVICLLIWVVSLLVSLPQIIYGHVQDIDKLICQY---HSEEISTM-----VLVIQMTLGFFLPLLTMILCYSGIIKTLLHARNFQK-------------HKSLKIIFLVVAVFLLTQTPFNLAMLIQSTSWEYYTITSFKYAIVVTEAIAYFRACLNPVLYAFVGLKFRKNVWKL 318
[Close]
BLAST of GCR070 vs. UniProt/SwissProt
Match: sp|Q9VZW5|FMAR_DROME (FMRFamide receptor OS=Drosophila melanogaster OX=7227 GN=FMRFaR PE=2 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 3.315e-13
Identity = 82/300 (27.33%), Postives = 142/300 (47.33%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSK--NFISLTWY-LGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIII--MNPNLSNFHKYVYNIILQMLIMIYG---PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKT--NRDQ-DLLNRQKNFNTN 1101
            ++L +   RSS+N LL  LA  D + L+++S  +     I  Y  H     +    FIS   + +G + +    ++  +V L+R++ V +P +A    T  RA+I        +  YN+PRFW+          K +I+  + P+     +   NI +    +I     P + L + N L+   + RA   RQ L   +++ R  G + T +L VVI  F+   LP  +L         I   +  I + L  +NSS+NF+IY + G++F+     +FFK   +RDQ DL++ + + + N
Sbjct:  136 IILSRPQMRSSINYLLTGLARCDTV-LIITSILLFGIPSIYPYTGHFFGYYNYVYPFISPAVFPIGMIAQTASIYMTFTVTLERYVAVCHPLKARALCTYGRAKIYFIVCVCFSLAYNMPRFWEVLTVTYPEPGKDVILHCVRPSRLRRSETYINIYIHWCYLIVNYIIPFLTLAILNCLIYRQVKRANRERQRL--SRSEKREIG-LATMLLCVVIVFFMLNFLP-LVLNISEAFYSTIDHKITKISNLLITINSSVNFLIYIIFGEKFKRIFLLIFFKRRLSRDQPDLIHYESSISNN 430
[Close]
BLAST of GCR070 vs. UniProt/SwissProt
Match: sp|Q8SWR3|SPR_DROME (Sex peptide receptor OS=Drosophila melanogaster OX=7227 GN=SPR PE=1 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 4.641e-10
Identity = 64/250 (25.60%), Postives = 119/250 (47.60%), Query Frame = 1 
Query:  448 WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAK-----AWDK--------RTCKWI-IIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQME-----TKMLIVVIGVFLFTELPSSILQAITTKNCFIYRI----LIPICDGLT----ILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVTIVS 1116
            W+ +++A+ R+I V +   A    T  R +  +A IA   F++ +PRF+D         W+          T  W+   +  +L     Y++ ++   L+    P I+L+  N LL  ++ +A+  R+ L+ ++N+ +   ++      T MLIVV+ VFL  E+P +++ A+   +  I       L  IC  LT    + +  INF IY    ++FRE  +++F         L  +K+ +T  +IV+
Sbjct:  184 WLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRFFDRTYMPLVIEWNGSPTEVCHLETSMWVHDYIGVDLYYTSYYLFRVLFVHLL----PCIILVTLNILLFAAMRQAQE-RRKLLFRENRKKECKKLRETNCTTLMLIVVVSVFLLAEIPIAVVTAMHIVSSLIIEFLDYGLANICIMLTNFFLVFSYPINFGIYCGMSRQFRETFKEIFLGR------LMAKKDSSTKYSIVN 422
[Close]
BLAST of GCR070 vs. UniProt/SwissProt
Match: sp|Q6DWJ6|GP139_HUMAN (Probable G-protein coupled receptor 139 OS=Homo sapiens OX=9606 GN=GPR139 PE=2 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 8.656e-8
Identity = 54/230 (23.48%), Postives = 93/230 (40.43%), Query Frame = 1 
Query:  448 WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYG------PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSI-----LQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFR---ENLRKMFFKTNRDQDLLNRQKNFN 1095
            WI V + +DR+I V +P + H  +   R + V  S+    F+ +IP +W +   W +                  Y+   +  +LI I+       P  +  + NS++   L R  N R        +   +G+  T +L  +  +F     P  I     L     +N ++  I+  I + L +LN++INF +Y    +RFR       K FFK  +         NF+
Sbjct:  117 WITVPLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYW-WPNIWTE-----------------DYISTSVHHVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRL-------RGYSTGK-TTAILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATLKAFFKCQKQPVQFYTNHNFS 320
[Close]
BLAST of GCR070 vs. UniProt/SwissProt
Match: sp|Q80UC8|GP139_MOUSE (Probable G-protein coupled receptor 139 OS=Mus musculus OX=10090 GN=Gpr139 PE=2 SV=2)

HSP 1 Score: 54.299 bits (129), Expect = 8.098e-7
Identity = 51/230 (22.17%), Postives = 93/230 (40.43%), Query Frame = 1 
Query:  448 WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYG------PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSI-----LQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFR---ENLRKMFFKTNRDQDLLNRQKNFN 1095
            WI V + +DR+I V +P + H  +   R + V  S+    F+ +IP +W +   W +                  Y+   +  +L+ I+       P  +  + NS++   L R  N R        +   +G+  T +L  +  +F     P  I     L     +N ++  I++ + + L +LN++INF +Y    +RFR       K  FK  +         NF+
Sbjct:  109 WITVPLTVDRYIAVCHPLKYHTVSYPARTRKVILSVYITCFLTSIPYYW-WPNIWTE-----------------DYISTSMHHVLVWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRL-------RGYSTGK-TTAILFTITSIFATLWAPRIIMILYHLYGAPIQNPWLVHIMLDVANMLALLNTAINFFLYCFISKRFRTMAAATLKALFKCQKQPVQFYTNHNFS 312
[Close]
BLAST of GCR070 vs. UniProt/SwissProt
Match: sp|P0C0W8|GP139_RAT (Probable G-protein coupled receptor 139 OS=Rattus norvegicus OX=10116 GN=Gpr139 PE=2 SV=1)

HSP 1 Score: 54.299 bits (129), Expect = 8.244e-7
Identity = 51/230 (22.17%), Postives = 93/230 (40.43%), Query Frame = 1 
Query:  448 WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYG------PMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSI-----LQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFR---ENLRKMFFKTNRDQDLLNRQKNFN 1095
            WI V + +DR+I V +P + H  +   R + V  S+    F+ +IP +W +   W +                  Y+   +  +L+ I+       P  +  + NS++   L R  N R        +   +G+  T +L  +  +F     P  I     L     +N ++  I++ + + L +LN++INF +Y    +RFR       K  FK  +         NF+
Sbjct:  109 WITVPLTVDRYIAVCHPLKYHTVSYPARTRKVILSVYITCFLTSIPYYW-WPNIWTE-----------------DYISTSMHHVLVWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRL-------RGYSTGK-TTAILFTITSIFATLWAPRIIMILYHLYGAPIQNPWLVHIMLDVANMLALLNTAINFFLYCFISKRFRTMAAATLKALFKCQKQPVQFYTNHNFS 312
[Close]
BLAST of GCR070 vs. TrEMBL
Match: A0A193KUI2 (GCR070 OS=Schmidtea mediterranea OX=79327 GN=gcr070 PE=2 SV=1)

HSP 1 Score: 686.411 bits (1770), Expect = 0.000e+0
Identity = 363/364 (99.73%), Postives = 363/364 (99.73%), Query Frame = 1 
Query:   88 MYLNNCLNSSSPKNEWCTEPSMVRFQXXXXXXXXXXXXXXXXXXXXXXXLVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVTIVSMKKQNNVDSKDDNFSFDNTEN 1179
            MYLNNCLNSSSPKNEWCTEPSMVRFQFVFNVFIVGLIIIFGFVGNFISILVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCF YRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVTIVSMKKQNNVDSKDDNFSFDNTEN
Sbjct:    1 MYLNNCLNSSSPKNEWCTEPSMVRFQFVFNVFIVGLIIIFGFVGNFISILVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFFYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVTIVSMKKQNNVDSKDDNFSFDNTEN 364
[Close]
BLAST of GCR070 vs. TrEMBL
Match: A0A1I8J5R9 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 1.173e-36
Identity = 101/287 (35.19%), Postives = 164/287 (57.14%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSS-YYIVF-ARGIIIYFSH---LLPEL-----SKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPN---LSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAI--------TTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENL 1032
            LVL++D +RSSM+VLL  L+V+D++F+L+S+ YY+V+   G ++  S    L   L     ++  + L WY G+V R GRNW+ + VALDR+++V+NPF + QR+   R++I   ++     VYNIP  ++Y     +  C  + I+ PN   L   +  +Y  I+ +L +  GPM++L  FN LL  SL+ A  +R ++  +  +       ETKML+V+I VF+ TE+P ++   +        T  N ++Y     I   LT+ NS+INF IY +  + FR N+
Sbjct:   51 LVLQRDVRRSSMSVLLMALSVFDLIFILISAPYYVVYMGLGAVVKLSDGVTLQTRLHATTGAQPLLPLLWYFGSVARTGRNWVILLVALDRYMVVQNPFYSTQRSNPQRSRIYCVAVTCTALVYNIPLLFEYKSELHQ--CLQLQILQPNPKRLGFVYMLLYKKIMYILFLTVGPMLVLTAFNILLIRSLLIASRIRAAITRETTRR----TEETKMLVVIIAVFVTTEIPGAVWHILLDTSFDDQTWFNSYLYS----IGSLLTLFNSAINFFIYCVWSRNFRRNM 327
[Close]
BLAST of GCR070 vs. TrEMBL
Match: A0A1I8H7D6 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 135.576 bits (340), Expect = 4.362e-32
Identity = 97/314 (30.89%), Postives = 166/314 (52.87%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPN-LSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAIT----TKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNR----DQDLLNRQKNFNTNVTIVSMKKQNNVDSKD 1149
            LVLK+D  +SSM+VLL  L+ +D +F+ LS+ YIV   G+ +    L+ + +   +   WYLG+  R  RNWI + VALDR+ +V+NPF + +R+   R++I   S++ A+ +YN+P   +Y     +     +    P  L   +  VY  ++  + +  GP++ L+VFN+LL  SL+ A  +R ++  +  +       +TKML+V+I VF+ TELP ++ Q +      K  + Y     I   LT+LNS++NF IY +    FR N+     +  R     Q     Q++       + ++  NN  +++
Sbjct:   57 LVLKRDIGKSSMSVLLLALSTFDTVFIGLSAPYIVVYMGLGV----LVRDSAGVALPAVWYLGSAARTARNWIILIVALDRYTVVQNPFMSGRRSNPRRSRIYCISVSAASLLYNLPLLLEYTVVPHRCLPLNVSQAQPERLGQVYMLVYKKLMHFIFLSLGPVLWLLVFNALLIRSLLVASRIRATITREATRR----TEDTKMLVVIIAVFVATELPGAVWQLLLDTNFEKGNWFYSYFYSIGSLLTLLNSAVNFFIYCVWSANFRRNMALALGRPPRRKKFQQPKPAAQRSLRFQTDEIRLEPMNNRKTEE 362
[Close]
BLAST of GCR070 vs. TrEMBL
Match: A0A1I8G3R4 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 6.377e-30
Identity = 101/328 (30.79%), Postives = 168/328 (51.22%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIY--------FSHLLPELSKNFISL--TWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPN-LSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAIT----TKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDL------LNRQKNFNTN-VTIVSMKKQNNVDSKDD 1152
            LVLK+D  +SSM+VLL  L+ +D +F+ LS+ YIV   G+ +            LL       ++L   WYLG+  R  RNWI + VALDR+ +V+NPF + +R+   R++I   S++ A+ +YN+P   +Y     +     +    P  L   +  VY  ++  + +  GP++ L+VFN+LL  SL+ A  +R ++  +  +       +TKML+V+I VF+ TELP ++ Q +      K  + Y     I   LT+LNS++NF IY +    FR N+     +  R + L        R   F T+ + +  M  +   ++ D+
Sbjct:   70 LVLKRDIGKSSMSVLLLALSTFDTVFIGLSAPYIVVYMGLGVLVRDSAGVQLQTLLNASPAIQVALPAVWYLGSAARTARNWIILIVALDRYTVVQNPFMSGRRSNPRRSRIYCISVSAASLLYNLPLLLEYTVVPHRCLPLNVSQAQPERLGYVYMLVYKKLMHFIFLSLGPVLWLLVFNALLIRSLLVASRIRATITREATRR----TEDTKMLVVIIAVFVATELPGAVWQLLLDTNFEKGNWFYSYFYSIGSLLTLLNSAVNFFIYCVWSANFRRNMALALGRPPRRKKLQQPKPAAQRSLRFQTDEIRLEPMNNRKTEEAADE 393
[Close]
BLAST of GCR070 vs. TrEMBL
Match: A0A4Y2ES94 (FMRFamide receptor OS=Araneus ventricosus OX=182803 GN=FMRFaR_0 PE=4 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 3.516e-20
Identity = 93/330 (28.18%), Postives = 165/330 (50.00%), Query Frame = 1 
Query:   85 NMYLNNCLNSSSPKNEWCTEPSMVRFQXXXXXXXXXXXXXXXXXXXXXXXLVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFAR-GIIIYFSHLLP-ELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFW-----DYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQME-TKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFK 1050
            N  L   LN + P   +   P +  F+F+    ++  I   G + N +S+++L +   RSS+N  L  LAV+D + L+ +   +   + G  + F  L   ++S   I + + +G + + G  W  V+V ++R+I V +P +A    T  RA+  +  I      YNIPRFW     +Y      RT   ++     ++  +  VY+I L +L+M + P ++L+VFN  +  ++ RA   RQ+L  KQ      G+     ML+ V+ VFL   + + ++  I   + F+   L+ + + L  +NSS+NFVIY + G++F+     +F K
Sbjct:   11 NALLREFLNMTEPLQPFDPLPEVSTFEFITEGALITTIGFLGVIANIVSLIILSRPQMRSSVNCGLQGLAVFDTIVLICAVLMLGLNKLGSRVQFLKLYTVDVSPFIIPVAYPVGLIAQTGSVWTTVAVTVERYIAVCHPLKAKSLCTYRRARSFNLFITLMAIFYNIPRFWEVEHTEYFAPDMNRTVYKVVASQLRVNKLYYEVYHIWLYLLVMYFIPFLVLMVFNIFIWQTVRRANRERQTLSRKQE-----GEFSLAMMLLCVVIVFLTCNILALLINIIEYFDIFL-PPLVRVSNLLVTINSSVNFVIYCIFGRKFKRTFLVLFCK 334
[Close]
BLAST of GCR070 vs. Ensembl Cavefish
Match: oprd1a (opioid receptor, delta 1a [Source:ZFIN;Acc:ZDB-GENE-990415-199])

HSP 1 Score: 51.6026 bits (122), Expect = 7.455e-7
Identity = 50/223 (22.42%), Postives = 107/223 (47.98%), Query Frame = 1 
Query:  466 ALDRFIMVRNPFRAHQRNTSFRAQIV-------SASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITT------KNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRK--MFFKTNRDQDLLNRQKN 1089
            ++DR+I V +P RA +  T  +A+I+       S++I     +  + R  +  K     T   +   +P+      + ++ + ++ + I+  ++ ++V      + ++R ++VR  L++   +   + +  T+M++VV+  F+    P  I   I T      +N F+      +C  L   NSS+N V+Y+   + F+   R+  + F+T  DQ+ L+R +N
Sbjct:  114 SVDRYIAVCHPVRALEFRTPAKAKIINVCIWILSSAIGVPIMIMAVTRVTEQGK-----TVCTLKFPDPD------WYWDTVTKICVFIFAFVVPVLVITICYGLMILRLRSVR--LLSGSKEKDRNMRRITRMVLVVVAAFIVCWTPIHIFIIIKTLVEVDQRNPFVIASW-HLCIALGYTNSSLNPVLYAFLDENFKRCFREFCLPFRTRTDQNSLSRARN 322
[Close]
BLAST of GCR070 vs. Ensembl Cavefish
Match: oprd1b (opioid receptor, delta 1b [Source:ZFIN;Acc:ZDB-GENE-030131-8473])

HSP 1 Score: 50.8322 bits (120), Expect = 1.244e-6
Identity = 51/224 (22.77%), Postives = 107/224 (47.77%), Query Frame = 1 
Query:  463 VALDRFIMVRNPFRAHQRNTSFRAQIV-------SASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSI------LQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRK--MFFKTNRDQDLLNRQKN 1089
            +++DR+I V +P +A +  T  +A+I+       S++I     V  + R  D  K     T   +   +P+      + Y+ + ++ + I+  ++ ++V      + ++R K+VR  L++   +   + +  T+M++VV+  F+    P  I      L  I  KN  +  I    C  L  +NSS+N V+Y+   + F+   R+  + F++  +Q+  +R +N
Sbjct:  145 MSVDRYIAVCHPVKALEFRTPVKAKIINVFIWILSSAIGIPIMVIAVTRVNDKGK-----TVCMLKFPDPD------WYYDTVTKICVFIFAFVVPVLVITICYGLMILRLKSVR--LLSGSKEKDRNMRRITRMVLVVVAAFIICWTPIHIFIIVKTLVEIDQKNPLVI-ISWHFCIALGYMNSSLNPVLYAFLDENFKRCFREFCLPFRSCMEQNSFSRARN 354
[Close]
BLAST of GCR070 vs. Ensembl Cavefish
Match: p2ry2.2 (purinergic receptor P2Y2 [Source:NCBI gene;Acc:107197486])

HSP 1 Score: 48.9062 bits (115), Expect = 5.117e-6
Identity = 67/295 (22.71%), Postives = 123/295 (41.69%), Query Frame = 1 
Query:  247 KDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIP--RFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCF---------------IYRILIPICDGLTILNSSINFVIYSMCGQRFRENL---RKMFFKTNRDQDL 1071
            K W  S   + +  L V D L++L   + I +      Y    +   S++F  L  +L     YG       ++L RF+ V +P R+    +  RA++VS ++     V+  P   F     A +   C         L N H  VY+  + +L  +  P ++++V N L+   L+    V  +       ++ S +   KM+I+V+  F+   LP  + +++    CF                Y++  P+       NS I+ ++Y M GQ FR ++    K  ++T + + L
Sbjct:   56 KQW--SPNTIYMINLTVCDTLYILTLPFLIYY------YADKNVWPFSESFCKLIRFLFYANLYGSILFLSCISLHRFLGVCHPVRSMHWVSPRRARLVSVAVWVIVLVFQAPVLYFSRTRNAGNDLVCH--DTTTEELFN-HFLVYSTAISVLFFVI-PFLVVLVCNGLMVRKLLEPTAVGGA------TSQRSKKKSVKMIIIVLLTFMLCFLPFHLTRSL--YYCFRHLQVSCGLLEGSSIAYKVTRPLASA----NSCIDPILYFMAGQGFRRSINRKNKKGYRTEKGKSL 326
[Close]
BLAST of GCR070 vs. Ensembl Nematostella
Match: EDO35030 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMQ7])

HSP 1 Score: 53.9138 bits (128), Expect = 5.379e-8
Identity = 63/280 (22.50%), Postives = 133/280 (47.50%), Query Frame = 1 
Query:  235 LVLKKDWK-RSSMNVLLCTLAVYDVLFLL-LSSYYIVFARGIIIYFSHLLPELSK---NFIS---LTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTC--KWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCF--IYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRK 1038
            LV+ K+ + R+ MN++L  LA+ D+   + ++S YI     I  +F H   +  +    FI+   LTW  G  + +      VS+A +R+  + NP   H+R +   A+I+       + +  IP F+ +  + ++  C  +W          +    Y+ +  + I+ + P  LL+ + S +  SL  A++  Q   A+    R    + TKMLI +  +++   +P+  +  +   +    + +++  +   L + NS++N  +Y++  + FR+ L++
Sbjct:   34 LVVHKNPRMRTPMNIILFNLAICDITVAMGMTSKYI-----ITKFFQHPTGDCGRYLCTFITSGNLTWVGGLASVF----CLVSLAYERYSAIVNPINIHKRTSKTSAKILCIIAWITSIMICIPEFFGHQYSKEREVCYQRW------PADEWLPQAYS-MFWLFIVGFIPSTLLVFYYSRIVRSLWFAEHPSQEAHAQMAALRYRKSV-TKMLIGISVIYMIGWMPTLFVFVLVYWHTGYQVGQVIGAVTAILVVFNSAVNPYVYALQSKSFRKQLKR 296
[Close]
BLAST of GCR070 vs. Ensembl Nematostella
Match: EDO47987 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKH9])

HSP 1 Score: 53.5286 bits (127), Expect = 5.741e-8
Identity = 75/311 (24.12%), Postives = 134/311 (43.09%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMN-VLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSK---------NFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFW--DYAKAWDKRTC--KWIIIMNPNLSNFHK----YVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRIL-IP--ICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLL---NRQKNFN 1095
            ++L+     SS+N  LL  LAV DV+  L  +   VF       F+H                NFI   W  G  + +      V++A++R+  + NP   H + T  R  +  A       ++N+P F+   Y K  D   C  KW    N  L+  +     +++  I   +++I  PMI+ +++              + +++  Q       Q   +M++VV  ++    LP+ +L  ++  +  +Y    IP  I   L  LNS++N  +YS+   RF+E  R+ F  +N  + LL   N++ N+ 
Sbjct:   49 IILRHRQMTSSLNGYLLINLAVSDVMVALFMTPQYVFR----FTFTHPGGRAGDWLCKMITGGNFI---WVGGAASAF----TLVAIAMERYHAIVNP--CHHQLTRKRLALTIAGSWIYAILFNLPLFFVIGYEKHGDDFRCPEKWT---NKPLAELYTVGAFFIFGAIPIGIMLIVYPMIIRVLW--------------QPNILPTQRPIIEKRQKAVRMMLVVTVLYFVCWLPNLVLYMMSQFHSDVYGYFHIPYVISIILVGLNSTMNPFVYSLHSSRFKEEFRRWFASSNTGKRLLVKDNKECNYG 329
[Close]
BLAST of GCR070 vs. Ensembl Nematostella
Match: EDO38235 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDJ2])

HSP 1 Score: 52.7582 bits (125), Expect = 7.915e-8
Identity = 56/223 (25.11%), Postives = 99/223 (44.39%), Query Frame = 1 
Query:  412 WYLGNVTRYGRNWIA--------VSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTC--KWIIIMNPNLSNFHKYVYNIILQMLIM--IYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMF 1044
            W    VT     WIA        V +AL+RF  V  PFR  QR T  + +I   +      ++ +P F       +  +C  KW  +      +    V+ +I+ +LIM  +YG           L I  +  K+  Q++   Q     + +  TKML++V  +++       IL  +          +  + + L +LNSS+N +I+++  QRFR++LR+++
Sbjct:   80 WLCKFVTGGNVAWIAAAASSFSLVVLALERFYAVMYPFR--QRFTLRKVKITVLTCWLYATLFMLPLFLVVEYDLNSGSCSEKWADLEAAGAFSTLTLVFLLIIPLLIMTILYG-----------LVIHKLWFKSSTQTIQPTQLAVEKTRKTVTKMLLIVTVIYVVCWSSDLILYMLLASQWNSNDPIYSLPEALVLLNSSVNPIIFTIYSQRFRQSLRRVY 289
[Close]
BLAST of GCR070 vs. Ensembl Nematostella
Match: EDO36609 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI86])

HSP 1 Score: 47.7506 bits (112), Expect = 4.943e-6
Identity = 58/257 (22.57%), Postives = 108/257 (42.02%), Query Frame = 1 
Query:  406 LTWYLGNVTRYGRN-WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRF--W-DYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQ-----------METKMLIVVIGVFLFTELPSSILQAITTKNCFIYR-----------ILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNT 1098
            + W + ++   G + W  V +++DRFI +  PFR H   T      + AS+   +FV  +  F  W DY K         I I   N    +  V +++L  L +     I+ +++  + T++L +A+ V  + +    QA   G               K+L +V+G F+    P  +L  ++  +  +             I       L +LNS++N +IY++  + FR +  K+F +  R +   +   N  T
Sbjct:  103 VAWIVVDIMCAGASIWNLVIISIDRFIAIVLPFRYHALMTPISGFGLIASVWGLSFVMAVLSFINWTDYGKPHFN-----IFISCANFDPIYYTVLSVVLFFLPL----FIVFVMYGHVFTVALTQARAV--AALQTDRQATTDGGRRGYINFLKEVKAAKVLAIVVGCFVVCWFPYFVLVLVSLWDPILLSRDTISPEQAKGINQTFVSALPVLNSTLNPIIYALFNKDFRRSFAKIFAQFCRRRVGSDDGNNLPT 348
[Close]
BLAST of GCR070 vs. Ensembl Nematostella
Match: EDO29863 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2F5])

HSP 1 Score: 46.9802 bits (110), Expect = 8.998e-6
Identity = 72/330 (21.82%), Postives = 127/330 (38.48%), Query Frame = 1 
Query:  259 RSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFIS------LTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCK--WIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSG-------QMETKMLIVVIGV---FLFTELP------SSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQ--DL--LNRQKNFNTNVTIVSMKKQNNVDSKDDNFSF 1164
            ++ MN LLC LA+ D L L+L S   +F +G    F H      +   +      L W  G    Y   +  V++A++R+  V  P    +R T  + + + A   F    +N   F  +    D   CK  W           HK    I   + +++ G + +  +F        + +  V +     +N   PSG       +M  K+  +V+ V   +    +P      +S+      K      I  P    +  +NS+IN +IY     +FR +L K+  +  R +  DL  L+   + NT    V + ++   + +     F
Sbjct:   38 KTPMNYLLCNLAISDTLLLVLFSPLYIF-QGT---FQHPQGAEGRALCATVTGGTLAWTCG----YASAYFLVAIAVERYFAVTKPCEPGRRITKKKLRWIVAGCWFGALSWNSVGFAVWGYDADSGFCKEDWP----------HKNSPKIYSSLSLLVVGALPVCTMF-------FLYSCVVHKLWFTGEN---PSGFAQFAALKMRKKVTSIVLAVSVVYTLCWIPELSIFVTSVFNPAVVKG----NIAYPAVVAMVTVNSAINPIIYCFHSGKFRRHLVKL-LRCGRAKSCDLRDLHEMHSGNTQDACVGVHRERRYECEKCEKKF 334
[Close]
BLAST of GCR070 vs. Ensembl Medaka
Match: gpr142 (probable G-protein coupled receptor 142 [Source:NCBI gene;Acc:101163443])

HSP 1 Score: 49.2914 bits (116), Expect = 3.747e-6
Identity = 54/241 (22.41%), Postives = 99/241 (41.08%), Query Frame = 1 
Query:  448 WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSI-----LQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVTIVSMKKQNNVDSKDDN 1155
            W  V + +DR++ + +P    Q +   RA+ + AS+        +P FW ++  W  R       ++  L         I   + I+ + P  +  V NSL+ I  +R +  RQ        A+  G+  T ML+ +  VF     P +      L   +  + +   +   + + L +LN+++NF +Y    + FR  +R +            RQ     N +I S+   NN  S+ D+
Sbjct:  121 WSTVPLTVDRYVALCHPLLHRQISYPARARRIIASVLALALASGVPFFW-WSDMW--RNSHPPTALDSVL---------IWTHVTIIYFLPCSIFFVLNSLI-IHTLRVRKRRQPCQKGHRPAQRLGK-TTAMLLAITSVFSVLWAPRTAVVIYHLYVSSVHSDWRVHLAYDLSNMLAMLNTAVNFFLYCFVSKPFRNVVRDVVLLRRWSLYSGPRQHQSPNNNSISSLYSGNNKRSQRDS 347
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BLAST of GCR070 vs. Planmine SMEST
Match: SMESG000070898.1 (SMESG000070898.1)

HSP 1 Score: 472.626 bits (1215), Expect = 6.326e-169
Identity = 230/232 (99.14%), Postives = 232/232 (100.00%), Query Frame = 1 
Query:  484 MVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVTIVSMKKQNNVDSKDDNFSFDNTEN 1179
            MVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVTI+SMKKQNNV+SKDDNFSFDNTEN
Sbjct:    1 MVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVTILSMKKQNNVNSKDDNFSFDNTEN 232
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BLAST of GCR070 vs. Planmine SMEST
Match: SMESG000046941.1 (SMESG000046941.1)

HSP 1 Score: 224.942 bits (572), Expect = 9.780e-70
Identity = 134/294 (45.58%), Postives = 184/294 (62.59%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIY----FSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQM-ETKMLIVVIGVFLFTELPSSILQAI---TTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMF-FKTNRDQDLLNRQKN 1089
            +VL +DW RSSM+VLL  L +YD+LFL+LS YYI+   GI +     F   +  L+   +   WYLGNV R GRNWIAV VA+DRF++V  PF+AH R+   RA++ S SIA     YNIPR W++ +   K   +  +I NP+L   +  +Y  IL  +  I GPMILLI+FN+LL IS+++A   RQ L+   NQ   S +  ETKML+VVIGVF+ TE PS   Q I     ++C I + ++   D LT+LNSS+NF IY +CG RFR+NL+K+F F+   +  + N   N
Sbjct:   49 IVLNRDWSRSSMSVLLSGLGMYDILFLILSIYYIIVYDGIKVIADEDFKSKILYLNNLIMKPAWYLGNVFRCGRNWIAVIVAIDRFVVVYRPFQAHSRSNPKRAKLYSLSIAILALFYNIPRLWEWKEIKTKSIIR--LIPNPDLGQTYHLIYGSILFAIFNIIGPMILLIIFNTLLAISVIKASKRRQVLI--NNQIGSSRRTRETKMLVVVIGVFIVTETPSCAWQIIMKHIQQSC-IGQSILSFVDILTVLNSSLNFFIYCICGLRFRQNLQKVFHFRCQTNYSVRNTTSN 337
[Close]
BLAST of GCR070 vs. Planmine SMEST
Match: SMESG000013112.1 (SMESG000013112.1)

HSP 1 Score: 82.0333 bits (201), Expect = 4.190e-17
Identity = 77/302 (25.50%), Postives = 148/302 (49.01%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPELSKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAH---QRNTSFRAQIVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAK-----NVRQSLMAKQNQARPSGQMETKMLIVVIGVFLFTELPSSILQ---AITTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVT 1107
            +VLK    RSS+++ L  L ++D + LL+ + +I    G ++ F +L     K F    +    V +    WI V +  +R+  V  P +A        SF   I+   I+  +  YN+PR+ +        +    +  + +   FHK+ Y+    ++IM + P+++L   N +L   L  ++     +  +SL++ +++   S    T+M++VV+ +F+F + P+ I      I   N   + I+  I + L ILNS++NF++Y   GQ+FR     +    N +++++NR ++   NVT
Sbjct:   28 IVLKNKVMRSSVSIYLLALTLWDTV-LLICALFI----GPLMRFENLRVIFFKIF----YPPALVAQTATIWITVGLTCERYFAVCFPLKAQFFISMKKSFWCVIL---ISLFSIFYNVPRWLEEIPMSINNSEHTFVNHSDSTIGFHKFYYSY-AYIVIMFFIPLLVLSSMNYMLIRELKNSQLYVLNDTNKSLISSKSRRIRSDNNVTRMIVVVVSIFIFCQFPALIYNIKFGIQPANDISWEIISEIRNFLVILNSAVNFILYCAFGQKFRRTFVHVIIPCNENENVVNR-RSLTNNVT 315
[Close]
BLAST of GCR070 vs. Planmine SMEST
Match: SMESG000007759.1 (SMESG000007759.1)

HSP 1 Score: 70.8626 bits (172), Expect = 3.461e-13
Identity = 72/259 (27.80%), Postives = 114/259 (44.02%), Query Frame = 1 
Query:  448 WIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYNIPRFWDY---AKAWD----------------------KRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQN--QARPSGQMETKMLIVVIGVFLFTELPSSILQAI-----TTKNCFIYRILIPICDGLTILNSSINFVIYSMCGQRFRENLRKMFFK-------------TNRDQDLLNRQKN 1089
            W+   ++++RF ++  PF+A +  +   A I +  +  A+ VYNIPRF++Y   +  W                       K    W  I     S   +  Y +   ++++  GP+I +++ NSLL I + R         AK+N        Q   KMLI VI  FL T++P+SI   I       K    Y I+  I + L ILNS+IN V Y +  +RFR+   K+  +             T+RD +  NR +N
Sbjct:  115 WLTTFLSVERFFIICYPFKAERICSLKIASINTTLVVAASLVYNIPRFFEYILWSADWSQPVLSDYLNTTSIYNFTNTQFLKMQYTWYDISEFGKSPSFRIWYTLYSWIVLVFLGPIITIVITNSLLLIEIKRVNR-----RAKRNNFNVVDVNQDTNKMLIGVIFFFLLTQIPASISHVIWAYMAGDKFQQWYFIINEIGNYLVILNSAINIVSYLIFSKRFRKEFIKIIKEIMGPRRFVEEQRGTSRDVEFSNRYRN 368
[Close]
BLAST of GCR070 vs. Planmine SMEST
Match: SMESG000005296.1 (SMESG000005296.1)

HSP 1 Score: 67.0106 bits (162), Expect = 7.477e-12
Identity = 79/332 (23.80%), Postives = 154/332 (46.39%), Query Frame = 1 
Query:  235 LVLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIY--FSHLLPELSKNF-ISLTWYLGNVT-----RYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQIVSASIAFATFVYN----IPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNIILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLM--AKQNQARPSG---QMETKMLIVVIGVFLFTELPSSILQAITTKNCFIYRI---------LIPICDGLTILNSSINFVIYSMCGQRFRENLRKMF-FKTNRDQDLLNRQKNFNTNVTIVSMKKQNNVDSKD 1149
            +VL K   RS  NV+L +LA+ D+       +  VF   + +   +   L +   N  IS+  ++ NV           W+ V +A+ R+I +  P +         +  +  ++ F +  +N     P+F  +       +   I++M  + S     +     ++L+M   P  LL+ F+ LL I++ +    R+ L+  +K+ ++R  G      ++ML+VV+ +FL  ELP+ I   I T +  ++           L  IC+  T+++   NF +Y    ++FRE  + +F F+ + D   L+R+++    + + +M + NN +SKD
Sbjct:   65 IVLNKRHMRSPTNVILMSLALADM-------FTGVFPLPVYLINNYPTFLTQYQNNITISVAIFVLNVVLPTICHTASIWLTVILAIQRYIYITMPLKVDHICKIKNSIKMVIAVIFLSICFNWPLISPQFLKFNLVCSDNSTH-ILVMKCHSSGSRLMIIYYFSRLLLMHVAPCALLLSFSVLLIIAMKKVAIRRRKLLNLSKKAESRMLGWDSNTTSRMLVVVVTIFLIVELPNGIFITIYTISQMLFITIFSDELLGKLTHICNLATMISYLFNFFVYCTMSKQFRETYKTLFGFEPSFD---LSRRRHSQPELALRAM-EMNNSESKD 384
The following BLAST results are available for this feature:
BLAST of GCR070 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
GPR1391.802e-823.48G protein-coupled receptor 139 [Source:HGNC Symbol... [more]
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BLAST of GCR070 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
frpr-82.382e-1323.68FMRFamide Peptide Receptor family [Source:UniProt... [more]
frpr-34.755e-1126.24FMRFamide Peptide Receptor family; VRFamide recept... [more]
frpr-71.269e-1022.75FMRFamide Peptide Receptor family [Source:UniProt... [more]
dmsr-82.330e-1025.24DroMyoSuppressin Receptor related [Source:UniProt... [more]
dmsr-63.277e-1031.82DroMyoSuppressin Receptor related [Source:UniProt... [more]
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BLAST of GCR070 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FMRFaR3.307e-1427.33gene:FBgn0035385 transcript:FBtr0340706[more]
FMRFaR3.307e-1427.33gene:FBgn0035385 transcript:FBtr0332085[more]
FMRFaR3.307e-1427.33gene:FBgn0035385 transcript:FBtr0072980[more]
SPR4.630e-1125.60gene:FBgn0029768 transcript:FBtr0344824[more]
SPR4.630e-1125.60gene:FBgn0029768 transcript:FBtr0339781[more]
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BLAST of GCR070 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
oprd1a1.409e-723.15opioid receptor, delta 1a [Source:ZFIN;Acc:ZDB-GEN... [more]
gpr1396.959e-723.49G protein-coupled receptor 139 [Source:NCBI gene;A... [more]
trhr27.811e-724.08thyrotropin releasing hormone receptor 2 [Source:Z... [more]
trhr28.464e-724.08thyrotropin releasing hormone receptor 2 [Source:Z... [more]
gpr1422.954e-622.76G protein-coupled receptor 142 [Source:ZFIN;Acc:ZD... [more]
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BLAST of GCR070 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
gpr1391.899e-824.67G protein-coupled receptor 139 [Source:NCBI gene;A... [more]
crybg13.458e-621.66crystallin beta-gamma domain containing 1 [Source:... [more]
GPR1423.752e-623.16G protein-coupled receptor 142 [Source:HGNC Symbol... [more]
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BLAST of GCR070 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Gpr1391.158e-722.17G protein-coupled receptor 139 [Source:MGI Symbol;... [more]
Cxcr68.149e-620.40chemokine (C-X-C motif) receptor 6 [Source:MGI Sym... [more]
Cxcr69.739e-620.40chemokine (C-X-C motif) receptor 6 [Source:MGI Sym... [more]
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BLAST of GCR070 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9VZW5|FMAR_DROME3.315e-1327.33FMRFamide receptor OS=Drosophila melanogaster OX=7... [more]
sp|Q8SWR3|SPR_DROME4.641e-1025.60Sex peptide receptor OS=Drosophila melanogaster OX... [more]
sp|Q6DWJ6|GP139_HUMAN8.656e-823.48Probable G-protein coupled receptor 139 OS=Homo sa... [more]
sp|Q80UC8|GP139_MOUSE8.098e-722.17Probable G-protein coupled receptor 139 OS=Mus mus... [more]
sp|P0C0W8|GP139_RAT8.244e-722.17Probable G-protein coupled receptor 139 OS=Rattus ... [more]
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BLAST of GCR070 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A193KUI20.000e+099.73GCR070 OS=Schmidtea mediterranea OX=79327 GN=gcr07... [more]
A0A1I8J5R91.173e-3635.19G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A1I8H7D64.362e-3230.89G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A1I8G3R46.377e-3030.79G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A4Y2ES943.516e-2028.18FMRFamide receptor OS=Araneus ventricosus OX=18280... [more]
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BLAST of GCR070 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
oprd1a7.455e-722.42opioid receptor, delta 1a [Source:ZFIN;Acc:ZDB-GEN... [more]
oprd1b1.244e-622.77opioid receptor, delta 1b [Source:ZFIN;Acc:ZDB-GEN... [more]
p2ry2.25.117e-622.71purinergic receptor P2Y2 [Source:NCBI gene;Acc:107... [more]
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BLAST of GCR070 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of GCR070 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of GCR070 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO350305.379e-822.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO479875.741e-824.12Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO382357.915e-825.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO366094.943e-622.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO298638.998e-621.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of GCR070 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
gpr1423.747e-622.41probable G-protein coupled receptor 142 [Source:NC... [more]
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BLAST of GCR070 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000070898.16.326e-16999.14SMESG000070898.1[more]
SMESG000046941.19.780e-7045.58SMESG000046941.1[more]
SMESG000013112.14.190e-1725.50SMESG000013112.1[more]
SMESG000007759.13.461e-1327.80SMESG000007759.1[more]
SMESG000005296.17.477e-1223.80SMESG000005296.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003601 ID=SMED30003601|Name=GCR070|organism=Schmidtea mediterranea sexual|type=transcript|length=1235bp
CTTCCGATCTATGAGTTTGAAATTTAGTTTTCCGCAATGAAACTATTTAC
TGTCAATTTTTCTAAAAGATCTTGAACCAGTGGAAACATGTATTTGAATA
ATTGCTTAAATTCTTCATCGCCAAAGAATGAATGGTGCACAGAACCGAGC
ATGGTGCGATTTCAGTTTGTTTTCAATGTTTTTATTGTGGGCTTGATAAT
AATTTTCGGTTTTGTTGGCAACTTTATATCAATATTGGTACTAAAGAAAG
ACTGGAAGAGATCATCCATGAATGTGCTACTTTGCACATTGGCTGTATAT
GACGTCCTGTTTTTACTTTTATCCTCATACTACATTGTATTTGCGAGAGG
AATAATAATCTACTTCTCTCATCTACTTCCTGAATTATCCAAAAATTTCA
TCTCATTAACTTGGTATTTAGGAAACGTTACCAGATATGGTCGTAATTGG
ATTGCAGTTTCTGTTGCATTGGATAGGTTTATAATGGTCAGAAATCCTTT
TAGAGCTCACCAACGTAATACATCATTTAGAGCTCAAATTGTAAGTGCAT
CCATTGCATTTGCTACTTTTGTTTACAATATTCCACGGTTCTGGGATTAC
GCAAAGGCTTGGGATAAAAGGACGTGTAAATGGATAATAATAATGAACCC
TAACCTTTCTAATTTCCATAAATATGTGTACAACATTATTTTACAGATGT
TAATCATGATATATGGACCCATGATTCTTCTGATAGTTTTTAACTCGCTT
TTAACAATAAGTTTAGTGCGGGCAAAAAATGTCCGACAAAGTCTAATGGC
AAAACAAAATCAAGCTCGGCCCTCTGGACAAATGGAAACAAAAATGCTCA
TTGTAGTAATTGGTGTTTTCCTCTTCACAGAACTACCGAGCTCGATTTTA
CAAGCAATCACGACGAAGAATTGTTTCATCTATAGAATTCTAATCCCGAT
TTGTGATGGTCTGACGATTTTGAATTCCTCGATAAATTTTGTCATTTACA
GCATGTGTGGCCAAAGATTCCGTGAGAATCTCAGAAAGATGTTTTTCAAA
ACCAATCGTGATCAAGACCTTTTGAATCGCCAGAAGAACTTTAATACGAA
CGTCACAATCGTGTCAATGAAAAAACAAAATAATGTTGACTCTAAAGATG
ATAATTTTTCTTTTGACAACACTGAAAACTGAATTTGTGATTTCATGATT
AATATTATAATCCCATCTGTAATTGTTTGAGATCG
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protein sequence of SMED30003601-orf-1

>SMED30003601-orf-1 ID=SMED30003601-orf-1|Name=SMED30003601-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=365bp
MYLNNCLNSSSPKNEWCTEPSMVRFQFVFNVFIVGLIIIFGFVGNFISIL
VLKKDWKRSSMNVLLCTLAVYDVLFLLLSSYYIVFARGIIIYFSHLLPEL
SKNFISLTWYLGNVTRYGRNWIAVSVALDRFIMVRNPFRAHQRNTSFRAQ
IVSASIAFATFVYNIPRFWDYAKAWDKRTCKWIIIMNPNLSNFHKYVYNI
ILQMLIMIYGPMILLIVFNSLLTISLVRAKNVRQSLMAKQNQARPSGQME
TKMLIVVIGVFLFTELPSSILQAITTKNCFIYRILIPICDGLTILNSSIN
FVIYSMCGQRFRENLRKMFFKTNRDQDLLNRQKNFNTNVTIVSMKKQNNV
DSKDDNFSFDNTEN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0008528G-protein coupled peptide receptor activity
GO:0004930G-protein coupled receptor activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR0194277TM_GPCR_serpentine_rcpt_Srw
IPR000276GPCR_Rhodpsn
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 29..53
score: 21.46
coord: 250..274
score: 24.2
coord: 200..223
score: 13.75
coord: 61..82
score: 28.44
coord: 112..134
score: 16.51
coord: 286..312
score: 27.68
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 16..329
e-value: 7.1E-45
score: 155.3
NoneNo IPR availablePANTHERPTHR46641FAMILY NOT NAMEDcoord: 11..359
NoneNo IPR availableCDDcd149787tmA_FMRFamide_R-likecoord: 28..312
e-value: 4.06347E-49
score: 165.499
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 6..325
NoneNo IPR availableTMHMMTMhelixcoord: 89..111
NoneNo IPR availableTMHMMTMhelixcoord: 254..276
NoneNo IPR availableTMHMMTMhelixcoord: 28..50
NoneNo IPR availableTMHMMTMhelixcoord: 147..169
NoneNo IPR availableTMHMMTMhelixcoord: 63..85
NoneNo IPR availableTMHMMTMhelixcoord: 200..222
NoneNo IPR availableTMHMMTMhelixcoord: 280..302
IPR0194277TM GPCR, serpentine receptor class w (Srw)PFAMPF103247TM_GPCR_Srwcoord: 37..320
e-value: 4.3E-14
score: 52.5
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 44..304
score: 24.685