Ras-like C3 botulinum toxin substrate 1
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30003600 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Human
Match: RAC1 (Rac family small GTPase 1 [Source:HGNC Symbol;Acc:HGNC:9801]) HSP 1 Score: 231.491 bits (589), Expect = 7.674e-75 Identity = 110/192 (57.29%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KC LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Human
Match: RAC2 (Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802]) HSP 1 Score: 230.72 bits (587), Expect = 1.604e-74 Identity = 109/192 (56.77%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPK-CSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD +NL LWDTAGQE YD+LR Y T VFL+CFS++ +YENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL LAK+I++VK++ECSA ++ GL VF+EAIRAV+ P R++ + CSLL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Human
Match: RAC3 (Rac family small GTPase 3 [Source:HGNC Symbol;Acc:HGNC:9803]) HSP 1 Score: 219.935 bits (559), Expect = 2.671e-70 Identity = 100/177 (56.50%), Postives = 132/177 (74.58%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVI 606 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PI+LVGTK+DLR ++ +TY +GL +A++I +VK++ECSA ++ GL VF+EAIRAV+ Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVL 177
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Human
Match: RAC1 (Rac family small GTPase 1 [Source:HGNC Symbol;Acc:HGNC:9801]) HSP 1 Score: 220.705 bits (561), Expect = 2.858e-70 Identity = 110/211 (52.13%), Postives = 141/211 (66.82%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNT-------------------SVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KC LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Human
Match: RHOG (ras homolog family member G [Source:HGNC Symbol;Acc:HGNC:672]) HSP 1 Score: 218.394 bits (555), Expect = 9.077e-70 Identity = 101/191 (52.88%), Postives = 136/191 (71.20%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M++IKCVVVGDG VGKTC LI YTTN FP EY+PT+FDN+ A VDG +NL+LWDTAGQE YD+LR Y T+VF++CFS+ +YENV++ W E+ ++CP +PI+LVGTK DLR + +T Q+G LAKQI+AV+++ECSA ++G+ +VF EA+RAV+N TP ++ C LL Sbjct: 1 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKRGRSCILL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Match: ced-10 (Ras-related protein ced-10 [Source:UniProtKB/Swiss-Prot;Acc:Q03206]) HSP 1 Score: 226.483 bits (576), Expect = 3.031e-73 Identity = 107/191 (56.02%), Postives = 137/191 (71.73%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG INL LWDTAGQE YD+LR Y T VFLVCF++ + ++ENV+ W E+ ++CP PIILVGTK DLR + V+ +G ++AK+I AVK++ECSA ++ GL QVF+EAIRAV+ + KK KC++L Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAGQEDYDRLRPLSYPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADLREDRDTVERLRERRLQPVSQTQGYVMAKEIKAVKYLECSALTQRGLKQVFDEAIRAVLTPPQRAKKSKCTVL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Match: mig-2 (Rac-like GTPase [Source:UniProtKB/TrEMBL;Acc:G5EBV3]) HSP 1 Score: 217.624 bits (553), Expect = 8.892e-70 Identity = 97/195 (49.74%), Postives = 141/195 (72.31%), Query Frame = 1 Query: 64 LKSHMKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 + S + IKCVVVGDG VGKTC LISYTT+ FP +YVPT+FDN+ A + +DG +NL LWDTAGQE YD+LR Y T VF++CFSV+ +++NV W EIR +CP P+ILVGTK+DLR A + S ++ +G+ +A++I AVK++ECSA +++GL+QVFE+A+R++++ P++KK C+++ Sbjct: 1 MSSPSRQIKCVVVGDGTVGKTCMLISYTTDSFPVQYVPTVFDNYSAQMSLDGNVVNLGLWDTAGQEDYDRLRPLSYPQTDVFILCFSVVSPVSFDNVASKWIPEIRQHCPDAPVILVGTKLDLRDEAEPMRALQAEGKSPISKTQGMKMAQKIKAVKYLECSALTQQGLTQVFEDAVRSILHPKPQKKKKSCNIM 195
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Match: rac-2 (Ras-related protein rac-2 [Source:UniProtKB/Swiss-Prot;Acc:Q94124]) HSP 1 Score: 207.608 bits (527), Expect = 8.280e-66 Identity = 102/195 (52.31%), Postives = 135/195 (69.23%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVIN--QTP--KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC L+SYTTN FP EY+ T+FD + N+MVDG INLSLWDTAGQ+ YDQ R + T VFLVCF++ + ++ENV+ W E+ ++CP PIILVGTK DLR + V++ +G ++AK+I AVK++ECSA ++ GL QVF+EAIR + QTP + KK C++L Sbjct: 1 MQAIKCVVVGDGAVGKTCLLLSYTTNAFPGEYILTVFDTYSTNVMVDGRPINLSLWDTAGQDDYDQFRHLSFPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADLREDRDTIERLRERRLQPVSHTQGYVMAKEIKAVKYLECSALTQIGLKQVFDEAIRTGLTPPQTPQTRAKKSNCTVL 195
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Match: cdc-42 (Cell division control protein 42 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q05062]) HSP 1 Score: 201.83 bits (512), Expect = 1.180e-63 Identity = 103/198 (52.02%), Postives = 133/198 (67.17%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLR-------HLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M+ IKCVVVGDG VGKTC LISYTTN+FP+EYVPT+FDN+ +M+ G L L+DTAGQE YD+LR Y T VFLVCFSV+ ++ENV+ W EI ++C K P +LVGT+VDLR LA ST+V G LAK++ AVK+VECSA +++GL VF+EAI A ++ + KK KC++L Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVAPASFENVREKWVPEISHHCSKTPFLLVGTQVDLRDDPGMLEKLAKNKQKPVSTDV-------GEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALDPPQQEKKKKCNIL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Match: rho-1 (Ras-like GTP-binding protein rhoA [Source:UniProtKB/Swiss-Prot;Acc:Q22038]) HSP 1 Score: 175.637 bits (444), Expect = 1.730e-53 Identity = 82/181 (45.30%), Postives = 119/181 (65.75%), Query Frame = 1 Query: 76 MKAI--KCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQ 612 M AI K V+VGDG GKTC LI ++ ++FP+ YVPT+F+N+ A++ VDG + L+LWDTAGQE YD+LR Y +T V L+CFS+ + EN+ W E+R++CP +PIILVG K DLR V ++G +A+QI A ++ECSAK+++G+ +VFE+A +A + Q Sbjct: 1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPDVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKRDLRSDPQTVRELAKMKQEPVKPEQGRAIAEQIGAFAYLECSAKTKDGIREVFEKATQAALQQ 181
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Fly
Match: Rac2 (gene:FBgn0014011 transcript:FBtr0076867) HSP 1 Score: 227.254 bits (578), Expect = 1.515e-73 Identity = 109/194 (56.19%), Postives = 143/194 (73.71%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAV---INQTPKRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD INL LWDTAGQE YD+LR Y T VFL+CFS+++ ++ENV+ W E+R++CP +PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA +++GL VF+EAIR+V + + PKR KC+LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLKDKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKRH--KCALL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Fly
Match: Rac2 (gene:FBgn0014011 transcript:FBtr0332800) HSP 1 Score: 227.254 bits (578), Expect = 1.515e-73 Identity = 109/194 (56.19%), Postives = 143/194 (73.71%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAV---INQTPKRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD INL LWDTAGQE YD+LR Y T VFL+CFS+++ ++ENV+ W E+R++CP +PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA +++GL VF+EAIR+V + + PKR KC+LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLKDKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKRH--KCALL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Fly
Match: Rac1 (gene:FBgn0010333 transcript:FBtr0072730) HSP 1 Score: 226.483 bits (576), Expect = 3.726e-73 Identity = 109/193 (56.48%), Postives = 142/193 (73.58%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQT--PKRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD INL LWDTAGQE YD+LR Y T VFL+CFS+++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA +++GL VF+EAIR+V+ PK K+ KC+LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLRDKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPVLQPKSKR-KCALL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Fly
Match: Rac1 (gene:FBgn0010333 transcript:FBtr0331868) HSP 1 Score: 226.483 bits (576), Expect = 3.726e-73 Identity = 109/193 (56.48%), Postives = 142/193 (73.58%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQT--PKRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD INL LWDTAGQE YD+LR Y T VFL+CFS+++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA +++GL VF+EAIR+V+ PK K+ KC+LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLRDKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPVLQPKSKR-KCALL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Fly
Match: Mtl (gene:FBgn0039532 transcript:FBtr0085192) HSP 1 Score: 207.994 bits (528), Expect = 7.045e-66 Identity = 100/191 (52.36%), Postives = 134/191 (70.16%), Query Frame = 1 Query: 79 KAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 + IKCVVVGDG VGKTC LISYTT+ FP EYVPT+FDN+ A + VD I ++L LWDTAGQE YD+LR Y T VFL+C+SV +++ENV W EI+++CP PIILVGTK+DLR + ++ + ++G LA +I AVK++ECSA ++ GL VFEEA+RAV+ P KR++ KC ++ Sbjct: 5 RPIKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKIDLREDRETLSGLAEQGLTPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEEAVRAVLRPEPLKRRQRKCLIM 195
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Match: rac1b (Rac family small GTPase 1b [Source:ZFIN;Acc:ZDB-GENE-060312-45]) HSP 1 Score: 230.335 bits (586), Expect = 1.575e-74 Identity = 110/192 (57.29%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++C PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KCSLL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCQTTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCSLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Match: rac3b (Rac family small GTPase 3b [Source:ZFIN;Acc:ZDB-GENE-080220-21]) HSP 1 Score: 228.794 bits (582), Expect = 5.975e-74 Identity = 108/192 (56.25%), Postives = 140/192 (72.92%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPK-CSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR +S +TY +GL +A++I AVK++ECSA ++ GL VF+EAIRAV+ P +K+ K C+L Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLSPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGKRCTLF 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Match: rac2 (Rac family small GTPase 2 [Source:ZFIN;Acc:ZDB-GENE-040625-27]) HSP 1 Score: 227.639 bits (579), Expect = 1.407e-73 Identity = 109/192 (56.77%), Postives = 139/192 (72.40%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL LAK+I+AVK++ECSA ++ GL VF+EAIRAV+ P K KK C +L Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDEKETIEKLKEKKLAPITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQPTKVKKKGCVML 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Match: rac2 (Rac family small GTPase 2 [Source:ZFIN;Acc:ZDB-GENE-040625-27]) HSP 1 Score: 227.639 bits (579), Expect = 1.407e-73 Identity = 109/192 (56.77%), Postives = 139/192 (72.40%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL LAK+I+AVK++ECSA ++ GL VF+EAIRAV+ P K KK C +L Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDEKETIEKLKEKKLAPITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQPTKVKKKGCVML 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Match: rac3a (Rac family small GTPase 3a [Source:ZFIN;Acc:ZDB-GENE-040718-256]) HSP 1 Score: 227.254 bits (578), Expect = 2.367e-73 Identity = 106/192 (55.21%), Postives = 140/192 (72.92%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +A++I AVK++ECSA ++ GL VF+EAIRAV+ P K++ KC++ Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGKKCTVF 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Match: rac1 (Rac family small GTPase 1 [Source:NCBI gene;Acc:448118]) HSP 1 Score: 231.491 bits (589), Expect = 6.956e-75 Identity = 110/192 (57.29%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KC LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Match: yju2 (YJU2 splicing factor homolog [Source:Xenbase;Acc:XB-GENE-5938025]) HSP 1 Score: 229.95 bits (585), Expect = 2.698e-74 Identity = 110/192 (57.29%), Postives = 138/192 (71.88%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRK-KPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD +NL LWDTAGQE YD+LR Y T VFL+CFS++ +YENV+ W E+R++CP PIILVGTK+DLR +S ++Y +GL LAK+I AVK++ECSA ++ GL VF+EAIRAV+ P R K KC +L Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKETIEKLKEKKLSPISYPQGLALAKEIEAVKYLECSALTQRGLKTVFDEAIRAVLCPPPSRPNKAKCVVL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Match: nab2 (NGFI-A binding protein 2 (EGR1 binding protein 2) [Source:Xenbase;Acc:XB-GENE-957953]) HSP 1 Score: 227.254 bits (578), Expect = 3.127e-73 Identity = 107/192 (55.73%), Postives = 139/192 (72.40%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR +S +TY +GL +A++I +VK++ECSA ++ GL VF+EAIRAV+ P KR KC++ Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKRLSPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKRAGKKCTVF 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Match: rhogl.1 (ras homolog family member G [Source:NCBI gene;Acc:100489878]) HSP 1 Score: 221.09 bits (562), Expect = 8.467e-71 Identity = 104/191 (54.45%), Postives = 139/191 (72.77%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M++IKCVVVGDG VGKTC LI YTTN FP EY+PT+FDN+ A VDG ++L+LWDTAGQE YD+LR Y T+VF++CFS+ T+YENVK+ W E+ ++CP +PI+LVGTK DLR+ A N +T +G LAKQI+AVK++ECSA +++G+ +VF EA+RAV+N TP + K C +L Sbjct: 1 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQTSVDGRTVSLNLWDTAGQEEYDRLRTLSYPQTNVFIICFSIASPTSYENVKHKWYPEVGHHCPNVPILLVGTKKDLRNNADVMKKLKEQNQMPITNHQGGNLAKQIHAVKYMECSALNQDGIKEVFAEAVRAVLNPTPVKDKKSCFIL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Match: rhogl.1 (ras homolog family member G like gene 1 [Source:NCBI gene;Acc:100216282]) HSP 1 Score: 220.32 bits (560), Expect = 1.887e-70 Identity = 102/191 (53.40%), Postives = 138/191 (72.25%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M+ IKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ A + VDG ++L+LWDTAGQE YD+LR Y T+VF++CFS+ ++Y NV++ W E+ ++CP +PI+LVGTK DLR+ + +++ T Q+G LAKQI AVK++ECSA ++G+ QVFEEA+RAV+ K+ KC LL Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNAFPEEYIPTVFDNYSAQMTVDGRTVSLNLWDTAGQEEYDRLRTLSYPQTNVFIICFSIGSPSSYANVRHKWHPEVSHHCPNVPILLVGTKQDLRNDSETIKKLKEQSLAPTTNQQGSSLAKQIGAVKYMECSALHQQGVRQVFEEAVRAVLYPVTKKNPKKCVLL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Match: Rac1 (Rac family small GTPase 1 [Source:MGI Symbol;Acc:MGI:97845]) HSP 1 Score: 231.491 bits (589), Expect = 5.268e-75 Identity = 110/192 (57.29%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KC LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Match: Rac2 (Rac family small GTPase 2 [Source:MGI Symbol;Acc:MGI:97846]) HSP 1 Score: 229.95 bits (585), Expect = 2.594e-74 Identity = 109/192 (56.77%), Postives = 140/192 (72.92%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPK-CSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD +NL LWDTAGQE YD+LR Y T VFL+CFS++ +YENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL LAK I++VK++ECSA ++ GL VF+EAIRAV+ P R++ + CSLL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKDIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRPCSLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Match: Rac3 (Rac family small GTPase 3 [Source:MGI Symbol;Acc:MGI:2180784]) HSP 1 Score: 219.935 bits (559), Expect = 1.834e-70 Identity = 100/177 (56.50%), Postives = 132/177 (74.58%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVI 606 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PI+LVGTK+DLR ++ +TY +GL +A++I +VK++ECSA ++ GL VF+EAIRAV+ Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVL 177
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Match: Rac1 (Rac family small GTPase 1 [Source:MGI Symbol;Acc:MGI:97845]) HSP 1 Score: 220.32 bits (560), Expect = 2.139e-70 Identity = 110/211 (52.13%), Postives = 141/211 (66.82%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNT-------------------SVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KC LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGDTCGKDRPSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Match: Rhog (ras homolog family member G [Source:MGI Symbol;Acc:MGI:1928370]) HSP 1 Score: 218.394 bits (555), Expect = 6.232e-70 Identity = 101/191 (52.88%), Postives = 136/191 (71.20%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M++IKCVVVGDG VGKTC LI YTTN FP EY+PT+FDN+ A VDG +NL+LWDTAGQE YD+LR Y T+VF++CFS+ +YENV++ W E+ ++CP +PI+LVGTK DLR + +T Q+G LAKQI+AV+++ECSA ++G+ +VF EA+RAV+N TP ++ C LL Sbjct: 1 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKRGRSCILL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Match: sp|Q6RUV5|RAC1_RAT (Ras-related C3 botulinum toxin substrate 1 OS=Rattus norvegicus OX=10116 GN=Rac1 PE=1 SV=1) HSP 1 Score: 231.491 bits (589), Expect = 3.685e-74 Identity = 110/192 (57.29%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KC LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Match: sp|P63001|RAC1_MOUSE (Ras-related C3 botulinum toxin substrate 1 OS=Mus musculus OX=10090 GN=Rac1 PE=1 SV=1) HSP 1 Score: 231.491 bits (589), Expect = 3.685e-74 Identity = 110/192 (57.29%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KC LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Match: sp|P63000|RAC1_HUMAN (Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1) HSP 1 Score: 231.491 bits (589), Expect = 3.685e-74 Identity = 110/192 (57.29%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KC LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Match: sp|P62999|RAC1_CANLF (Ras-related C3 botulinum toxin substrate 1 OS=Canis lupus familiaris OX=9615 GN=RAC1 PE=2 SV=1) HSP 1 Score: 231.491 bits (589), Expect = 3.685e-74 Identity = 110/192 (57.29%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KC LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Match: sp|P62998|RAC1_BOVIN (Ras-related C3 botulinum toxin substrate 1 OS=Bos taurus OX=9913 GN=RAC1 PE=1 SV=1) HSP 1 Score: 231.491 bits (589), Expect = 3.685e-74 Identity = 110/192 (57.29%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KC LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. TrEMBL
Match: A0A4U5U475 (Ras-related C3 botulinum toxin substrate 2 GX OS=Collichthys lucidus OX=240159 GN=D9C73_002644 PE=4 SV=1) HSP 1 Score: 237.654 bits (605), Expect = 4.511e-74 Identity = 114/192 (59.38%), Postives = 142/192 (73.96%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVI-NQTPKRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD +NL LWDTAGQE YD+LR Y T VFL+CFS++ +YENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL LAK+I+AVK++ECSA ++ GL VF+EAIRAV+ QTPK KK CSLL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWYPEVRHHCPSTPIILVGTKLDLRDEKDTIEKLKEKKLAPITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQTPKVKKKGCSLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. TrEMBL
Match: A0A553P2W1 (Uncharacterized protein OS=Tigriopus californicus OX=6832 GN=TCAL_01129 PE=4 SV=1) HSP 1 Score: 234.958 bits (598), Expect = 4.264e-73 Identity = 111/192 (57.81%), Postives = 144/192 (75.00%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRK-KPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG INL LWDTAGQE YD+LR Y T VFL+CFS+++ ++ENV+ W E+R++CP +PIILVGTK+DLR + +S +TY +GL +AK + AVK++ECSA +++GL VF+EAIRAV+ PK K + KC+LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSVPIILVGTKLDLRDEKDTIDKLKEKRLSPITYPQGLAMAKDVGAVKYLECSALTQKGLKTVFDEAIRAVLCPAPKPKPRRKCNLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. TrEMBL
Match: A0A3Q3EYP8 (Rac family small GTPase 1 OS=Labrus bergylta OX=56723 GN=RAC1 (1 of many) PE=4 SV=1) HSP 1 Score: 234.572 bits (597), Expect = 6.872e-73 Identity = 110/192 (57.29%), Postives = 143/192 (74.48%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W+ E+R++CP PIILVGTK+DLR +S + Y +GL +AK+IN+VK++ECSA ++ GL VF+EAIRAV+ P K++K KC+LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWSPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLSPIIYPQGLAMAKEINSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCTLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. TrEMBL
Match: A0A084VDM0 (Rac gtpase OS=Anopheles sinensis OX=74873 GN=ZHAS_00003093 PE=4 SV=1) HSP 1 Score: 234.187 bits (596), Expect = 8.814e-73 Identity = 111/191 (58.12%), Postives = 142/191 (74.35%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG INL LWDTAGQE YD+LR Y T VFL+CFS+++ ++ENV+ W E+R++CP IPIILVGTK+DLR + +S +TY +GL +AK+I AVK++ECSA +++GL VF+EAIRAV+ KK KC +L Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPNIPIILVGTKLDLRDDKNTVDKLRDKKLSPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRAVLCPMIPPKKSKCKIL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. TrEMBL
Match: A0A182ISJ0 (Uncharacterized protein OS=Anopheles atroparvus OX=41427 PE=4 SV=1) HSP 1 Score: 234.187 bits (596), Expect = 8.814e-73 Identity = 111/191 (58.12%), Postives = 142/191 (74.35%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG INL LWDTAGQE YD+LR Y T VFL+CFS+++ ++ENV+ W E+R++CP IPIILVGTK+DLR + +S +TY +GL +AK+I AVK++ECSA +++GL VF+EAIRAV+ KK KC +L Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPNIPIILVGTKLDLRDDKNTVDKLRDKKLSPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRAVLCPMIPPKKSKCKIL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Match: rac1b (ras-related C3 botulinum toxin substrate 1-like [Source:NCBI gene;Acc:111192975]) HSP 1 Score: 231.876 bits (590), Expect = 3.441e-75 Identity = 110/192 (57.29%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K +K KC+LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDQDTIEKLKERKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKSRKRKCTLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Match: rac1a (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:103034053]) HSP 1 Score: 231.491 bits (589), Expect = 4.137e-75 Identity = 110/192 (57.29%), Postives = 141/192 (73.44%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ P K++K KC LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Match: rac1b (ras-related C3 botulinum toxin substrate 1-like [Source:NCBI gene;Acc:111192975]) HSP 1 Score: 229.18 bits (583), Expect = 3.779e-74 Identity = 109/192 (56.77%), Postives = 140/192 (72.92%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ L VF+EAIRAV+ P K +K KC+LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDQDTIEKLKERKLTPITYPQGLAMAKEIGAVKYLECSALTQRDLKTVFDEAIRAVLCPPPVKSRKRKCTLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Match: rac1b (ras-related C3 botulinum toxin substrate 1-like [Source:NCBI gene;Acc:111192975]) HSP 1 Score: 229.18 bits (583), Expect = 3.779e-74 Identity = 109/192 (56.77%), Postives = 140/192 (72.92%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ L VF+EAIRAV+ P K +K KC+LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDQDTIEKLKERKLTPITYPQGLAMAKEIGAVKYLECSALTQRDLKTVFDEAIRAVLCPPPVKSRKRKCTLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Match: rac3b (ras-related C3 botulinum toxin substrate 3-like [Source:NCBI gene;Acc:111192386]) HSP 1 Score: 228.794 bits (582), Expect = 5.064e-74 Identity = 108/192 (56.25%), Postives = 140/192 (72.92%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPK-CSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR +S +TY +GL +A++I AVK++ECSA ++ GL VF+EAIRAV+ P +K+ K C+L Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLSPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGKRCTLF 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007368.1 (pep scaffold:Pmarinus_7.0:GL476419:214196:224439:-1 gene:ENSPMAG00000006646.1 transcript:ENSPMAT00000007368.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 224.557 bits (571), Expect = 4.977e-73 Identity = 107/193 (55.44%), Postives = 139/193 (72.02%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPK--RKKPKCSLL 648 M+AIKCVVVGDG VGKTC LIS++ N FP EY+PT+FDN+ NLMVDG +NL LWDTAGQE YD+LR Y T +FL+CFSV+ ++Y+NV+ W KE+R++CP+ PIILVGTK D R ++ VT +GL LAK+I A+K++ECSA ++ GL VF+E +RAVI+ PK RKK C+LL Sbjct: 1 MQAIKCVVVGDGAVGKTCMLISFSNNTFPGEYIPTVFDNYAVNLMVDGKYVNLGLWDTAGQEDYDRLRPLSYPQTDIFLICFSVVSPSSYDNVRVKWFKEVRHHCPETPIILVGTKQDQREDKDILKHLEEKSMQPVTNAQGLSLAKEIGAIKYLECSALTQRGLKNVFDETVRAVISPEPKIERKKKSCALL 193
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009835.1 (pep scaffold:Pmarinus_7.0:GL479385:19931:31465:1 gene:ENSPMAG00000008880.1 transcript:ENSPMAT00000009835.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 223.016 bits (567), Expect = 1.767e-72 Identity = 103/177 (58.19%), Postives = 132/177 (74.58%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVI 606 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL +AK+I AVK++ECSA ++ GL VF+EAIRAV+ Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTVEKLREKKLAPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 177
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004439.1 (pep scaffold:Pmarinus_7.0:GL476335:1598569:1600956:1 gene:ENSPMAG00000004041.1 transcript:ENSPMAT00000004439.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 179.874 bits (455), Expect = 1.286e-55 Identity = 89/196 (45.41%), Postives = 126/196 (64.29%), Query Frame = 1 Query: 76 MKAI--KCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNS---TNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M AI K V+VGDG GKTC LI ++ ++FP YVPT+F+N+ A++ VDG + L+LWDTAGQE YD+LR Y +T V L+CFS+ + EN+ W E++++CP +PIILVG K DLR+ DNT V +EG +A +INA ++ECSAK+++G+ +VFE A RA + ++K C LL Sbjct: 1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRN---DDNTKRELAKMKQEPVRVEEGRDMANRINAFGYMECSAKTKDGVREVFEMATRAALQVRKRKKTGGCRLL 193
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Match: rhoj (ras homolog family member J [Source:ZFIN;Acc:ZDB-GENE-040724-272]) HSP 1 Score: 178.718 bits (452), Expect = 6.290e-55 Identity = 84/185 (45.41%), Postives = 121/185 (65.41%), Query Frame = 1 Query: 85 IKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKC 639 +KCVVVGDG VGKTC ++SY + FP +YVPT+FD++ N+ V G L L+DTAGQE Y QLR Y NT +F++CFSV++ +Y NVK W E+R CP +P +LVGT++DLR +T+Q+G+ LAKQI A ++ECSA +++GL VF+EAI ++ + ++ +C Sbjct: 21 LKCVVVGDGAVGKTCLIMSYANDAFPEQYVPTVFDHYAVNVKVGGSCYLLGLYDTAGQEDYHQLRPLSYPNTDMFMICFSVVNPASYHNVKEEWVPELRACCPDVPYLLVGTQIDLRDATKTLMRLKELKEKPMTHQQGVKLAKQIGAHCYLECSALTQKGLKAVFDEAILTILQRKKCKRSTRC 205
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001838.1 (pep scaffold:Pmarinus_7.0:GL478831:173097:182385:-1 gene:ENSPMAG00000001664.1 transcript:ENSPMAT00000001838.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 175.252 bits (443), Expect = 9.873e-54 Identity = 84/184 (45.65%), Postives = 119/184 (64.67%), Query Frame = 1 Query: 76 MKAI--KCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPK 621 M AI K V+VGDG GKTC LI ++ ++FP YVPT+F+N+ A++ VDG + L+LWDTAGQE YD+LR Y +T V L+CFS+ + EN+ W E++++CP +PIILVG K DLR+ V +EG +A +INA ++ECSAK+++G+ +VFE A RA + T K Sbjct: 1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDESTRRELAKMKQEPVKSEEGRDMANRINAFGYMECSAKTKDGVREVFEMATRAALQLTAK 184
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Match: CDC42 (Small rho-like GTPase; essential for establishment and maintenance of cell polarity; plays a role late in cell fusion via activation of key cell fusion regulator Fus2p; mutants have defects in the organization of actin and septins; human homolog CDC42 can complement yeast cdc42 mutant [Source:SGD;Acc:S000004219]) HSP 1 Score: 196.438 bits (498), Expect = 2.338e-62 Identity = 92/191 (48.17%), Postives = 130/191 (68.06%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M+ +KCVVVGDG VGKTC LISYTTN+FP +YVPT+FDN+ +M+ L L+DTAGQE YD+LR Y +T VFLVCFSV+ ++ENVK W E+ ++CP +P ++VGT++DLR + + +T ++G LA+++ AVK+VECSA ++ GL VF+EAI A + +K KC++L Sbjct: 1 MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLRDDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAALEPPVIKKSKKCAIL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Match: RHO1 (GTP-binding protein of the rho subfamily of Ras-like proteins; involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p) [Source:SGD;Acc:S000006369]) HSP 1 Score: 163.31 bits (412), Expect = 3.388e-49 Identity = 81/171 (47.37%), Postives = 110/171 (64.33%), Query Frame = 1 Query: 88 KCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRA 600 K V+VGDG GKTC LI ++ +FP YVPT+F+N+ A++ VDG + L+LWDTAGQE YD+LR Y +++V L+CFS+ + ENV+ W E+ ++C +PIILVG KVDLR+ VT QEG +A QI A + ECSAK+ G+ +VFE A RA Sbjct: 12 KLVIVGDGACGKTCLLIVFSKGQFPEVYVPTVFENYVADVEVDGRRVELALWDTAGQEDYDRLRPLSYPDSNVVLICFSIDLPDSLENVQEKWIAEVLHFCQGVPIILVGCKVDLRNDPQTIEQLRQEGQQPVTSQEGQSVADQIGATGYYECSAKTGYGVREVFEAATRA 182
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Match: RHO4 (Non-essential small GTPase; member of the Rho/Rac subfamily of Ras-like proteins; likely to be involved in the establishment of cell polarity; has long N-terminal extension that plays an important role in Rho4p function and is shared with Rho4 homologs in other yeasts and filamentous fungi [Source:SGD;Acc:S000001763]) HSP 1 Score: 154.451 bits (389), Expect = 6.630e-45 Identity = 77/178 (43.26%), Postives = 111/178 (62.36%), Query Frame = 1 Query: 85 IKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLM-VDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQT 615 +K VVVGDG VGKTC LISY FP +Y+PT+F+N+ N+ +G I L+LWDTAGQE Y +LR Y N V +VC+SV +T+ +NV+ W E++++CP PI+LVG K DL DN S+ V LAK++ A ++CSA+ +E + +VFE AI +++ + Sbjct: 73 LKIVVVGDGAVGKTCLLISYVQGTFPTDYIPTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRLRPLSYTNADVLMVCYSVGSKTSLKNVEDLWFPEVKHFCPSTPIMLVGLKSDLYE---ADNLSD-----LVEPSSAESLAKRLGAFAHIQCSARLKENIDEVFETAIHTLLSDS 242
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Match: RHO5 (Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; RAC1 ortholog; regulated by phosphorylation and ubiquitination; likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity [Source:SGD;Acc:S000005124]) HSP 1 Score: 152.14 bits (383), Expect = 1.739e-43 Identity = 85/233 (36.48%), Postives = 121/233 (51.93%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMV---------------DGIGI---------------NLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYC-----------PKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVI--NQTPKRKKPKCSL 645 M++IKCV++GDG VGKT LISYTTN FP +YVPT+FDN+ + + D G ++LWDTAGQE YD+LR CY T +FL+CFSV + ++ NV W E++ K PI+LVGTK DLR N YV+ +E L ++ + + ECSA ++ G+ +VFE+A+R I ++P +K +L Sbjct: 1 MRSIKCVIIGDGAVGKTSLLISYTTNSFPTDYVPTVFDNYSTTIAIPNGTASSPLELDNGNDKRGSLSSASSSPSTDRKLYKINLWDTAGQEDYDRLRPLCYPQTDIFLICFSVSEHASFANVTEKWLPELKQTSNIEGTSLYTKLGKYPILLVGTKSDLRDDPATQKKLQEANSDYVSQEEIDELVQRCGFMGYTECSAATQAGVREVFEQAVRYAIYEPESPNQKSANHTL 233
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Match: RHO3 (Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p [Source:SGD;Acc:S000001380]) HSP 1 Score: 148.288 bits (373), Expect = 3.655e-43 Identity = 79/200 (39.50%), Postives = 117/200 (58.50%), Query Frame = 1 Query: 88 KCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRH-----LAI---------------GDN---TSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP 618 K V++GDG GKT L +T FP Y PT+F+N+ ++ VD I LSLWDTAGQE +D+LR Y +T ++CFS+ R + ENV+ W EI ++C + ++LV K DLR+ AI G+N TSN N+ ++Y+EGL +AK+I A++++ECSAK +G+++ F EA R + P Sbjct: 18 KIVILGDGACGKTSLLNVFTRGYFPEVYEPTVFENYIHDIFVDSKHITLSLWDTAGQEEFDRLRSLSYSDTQCIMLCFSIDSRDSLENVQNKWVGEITDHCEGVKLVLVALKCDLRNNENESNAITPNNIQQDNSVSNDNGNNINSTSNGKNL--ISYEEGLAMAKKIGALRYLECSAKLNKGVNEAFTEAARVALTAGP 215
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Match: EDO38536 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCK6]) HSP 1 Score: 226.868 bits (577), Expect = 1.026e-73 Identity = 109/194 (56.19%), Postives = 139/194 (71.65%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPK---CSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG INL LWDTAGQE YD+LR Y T VFL+CFS++ +YENV+ W E+ ++CP PI+LVGTK+DLR + + + Y +GL +AK+I AVK++ECSA +++GL VF+EAIRAV+ T KKP+ C LL Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASYENVRAKWYPEVSHHCPNTPIVLVGTKLDLRDDKETIDKLKEKKLGPIGYTQGLQMAKEIGAVKYLECSALTQKGLKTVFDEAIRAVLCPTKPAKKPRNKGCKLL 194
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Match: EDO35019 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMN7]) HSP 1 Score: 213.001 bits (541), Expect = 2.279e-68 Identity = 100/178 (56.18%), Postives = 128/178 (71.91%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVIN 609 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG INL LWDTAGQE YD+LR Y T VFL+CFSV+ ++ENV+ W E+ ++CP PIILVGTK DLR ++ ++ GL +AK+I A K++ECSA +++GL VF++AIRAV+ Sbjct: 1 MQAIKCVVVGDGAVGKTCMLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSVISPASFENVRAKWYPEVSHHCPGTPIILVGTKTDLREDKEMIEKLKEKKLNPLSTSHGLQMAKEIKAAKYLECSALTQKGLKTVFDDAIRAVLE 178
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Match: EDO37472 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFJ1]) HSP 1 Score: 204.527 bits (519), Expect = 5.356e-65 Identity = 99/191 (51.83%), Postives = 129/191 (67.54%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M+ IKCVVVGDG VGKTC LISYTTN+FP+EYVPT+FDN+ +M+ G L L+DTAGQE YD+LR Y T VFLVCFSV+ +++ENVK W EI ++CPK P +LVGT+VDLR + + + LA+++ AVK+VECSA +++GL VF+EAI A + +KK KC LL Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQVDLRDDQGTIEKLSKNKQKPIAVEAAEKLARELRAVKYVECSALTQKGLKNVFDEAILAALEPPEPQKKKKCRLL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Match: EDO39465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Y5]) HSP 1 Score: 173.711 bits (439), Expect = 4.812e-53 Identity = 90/193 (46.63%), Postives = 126/193 (65.28%), Query Frame = 1 Query: 76 MKAI--KCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M AI K V+VGDG GKTC LI ++ ++FP YVPT+F+N+ A++ VDG + L+LWDTAGQE YD+LR Y +T V L+CFS+ + EN+ W E++++CP +PIILVG K DLR V +EG +A +I+A ++ECSAK+++G+ +VFE A RA + QT K+KK KC LL Sbjct: 1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRMDENTKRELQKMKQEPVKIEEGRAMADKISAYAYLECSAKTKDGVREVFETATRAAL-QTKKKKKGKCVLL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Match: EDO36554 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI96]) HSP 1 Score: 144.821 bits (364), Expect = 7.496e-42 Identity = 72/189 (38.10%), Postives = 110/189 (58.20%), Query Frame = 1 Query: 85 IKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLM-VDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 +K +VGDG VGKT I+ TN FP EY+PT +D + VDGI L+D+AG E +D+LR Y NT +FLVCF + R ++ENV W E+ ++ P +P +LVG K DLR + +S ++ +V+Y+EG A+ ++++E SA E + +V +IR + PK+ K KC ++ Sbjct: 7 LKLYIVGDGAVGKTALFITAATNTFPTEYIPTAYDASEQDFFNVDGIKYQAVLFDSAGGEDFDRLRPLGYPNTDIFLVCFDIAHRASFENVALRWLPELDHFSPGVPRVLVGNKKDLRP---KQDQEDSHSIDFVSYEEGKEAAQNFK-MQYIENSALLNENVKEVITTSIRIARDNLPKKGKRKCHVM 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Match: ENSORLT00000038381.1 (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:101175028]) HSP 1 Score: 231.106 bits (588), Expect = 6.344e-75 Identity = 110/192 (57.29%), Postives = 140/192 (72.92%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKP-KCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR +S + Y +GL +AK+I+AVK++ECSA ++ GL VF+EAIRAV+ P RKK KC +L Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPVTPIILVGTKLDLRDDKDTIEKLKEKKLSPIIYPQGLAMAKEISAVKYLECSALTQRGLKTVFDEAIRAVLCPPPDRKKKRKCRIL 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Match: ENSORLT00000041989.1 (Rac family small GTPase 2 [Source:NCBI gene;Acc:101163549]) HSP 1 Score: 229.565 bits (584), Expect = 2.114e-74 Identity = 110/192 (57.29%), Postives = 139/192 (72.40%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTP-KRKKPKCSLL 648 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD +NL LWDTAGQE YD+LR Y T VFL+CFS++ +YENV+ W E+R++CP PIILVGTK+DLR ++ +TY +GL LAK+I+AVK++ECSA ++ GL VF+EAIRAV+ P K KK C +L Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWYPEVRHHCPSTPIILVGTKLDLRDEKDTIEKLKEKKLAPITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQPAKVKKANCLML 192
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Match: RAC1 (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:101159016]) HSP 1 Score: 224.557 bits (571), Expect = 2.518e-72 Identity = 103/177 (58.19%), Postives = 132/177 (74.58%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVI 606 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR +S +TY +GL +AK+I +VK++ECSA ++ GL VF+EAIRAV+ Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKETTEKLKEKKLSPITYPQGLAMAKEIGSVKYLECSALTQRGLKTVFDEAIRAVL 177
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Match: RAC1 (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:101159016]) HSP 1 Score: 224.557 bits (571), Expect = 2.518e-72 Identity = 103/177 (58.19%), Postives = 132/177 (74.58%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVI 606 M+AIKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVDG +NL LWDTAGQE YD+LR Y T VFL+CFS++ ++ENV+ W E+R++CP PIILVGTK+DLR +S +TY +GL +AK+I +VK++ECSA ++ GL VF+EAIRAV+ Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKETTEKLKEKKLSPITYPQGLAMAKEIGSVKYLECSALTQRGLKTVFDEAIRAVL 177
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Match: rhogb (rho-related GTP-binding protein RhoG [Source:NCBI gene;Acc:101162944]) HSP 1 Score: 208.379 bits (529), Expect = 3.946e-66 Identity = 95/191 (49.74%), Postives = 134/191 (70.16%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M+ +KCVVVGDG VGKTC LISYTT FP EY+PT+FDN+ + + VDG I+L+LWDTAGQE YD+LR Y T+VF++CFS+ ++ENVK+ W E+ ++CP +PI+LVGTK DLR+ N + +++ +G LA+QI A++++ECSA +++G+ VF EA+RA +N P K C LL Sbjct: 1 MQTVKCVVVGDGAVGKTCLLISYTTGAFPKEYIPTVFDNYSSQVTVDGRVISLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSISSPASFENVKHKWHPEVSHHCPGVPILLVGTKSDLRNNEELVKKLKEQNQAPISHSQGTSLARQIQALRYLECSALNQDGIKDVFVEAVRAYLNPQPTVNKRPCVLL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Planmine SMEST
Match: SMESG000005013.1 (SMESG000005013.1) HSP 1 Score: 398.282 bits (1022), Expect = 8.271e-141 Identity = 191/191 (100.00%), Postives = 191/191 (100.00%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL Sbjct: 1 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 191
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Planmine SMEST
Match: SMESG000024961.1 (SMESG000024961.1) HSP 1 Score: 230.72 bits (587), Expect = 6.140e-75 Identity = 106/185 (57.30%), Postives = 137/185 (74.05%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKK 630 M+ IKCVVVGDG VGKTC LISYTTN FP EY+PT+FDN+ AN+MVD +NL LWDTAGQE YD+LR Y T VFL+CFS+++ ++YENV+ W EI ++CP PIILVGTK+DLR + + ++Y +GL+LAK+I AVK++ECSA +++GL VF+EAIRAV+ P RKK Sbjct: 1 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKK 185
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Planmine SMEST
Match: SMESG000005010.1 (SMESG000005010.1) HSP 1 Score: 226.483 bits (576), Expect = 3.547e-73 Identity = 111/195 (56.92%), Postives = 144/195 (73.85%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLR-HLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPK---CSLL 648 M++IKCVVVGDG VGKTC LISYTT+ FP +VPT+FDN AN+M++G INL LWDTAGQE YD+LR Y T VFL+CFS++++ ++ NVK W KE+ ++ + PIILVGTK+DLR A+ +N N S VTYQ+GL L ++I AVK++ECSA+++ L QVFEEAIR VIN+ PK P+ CSLL Sbjct: 1 MRSIKCVVVGDGAVGKTCILISYTTDAFPTTHVPTVFDNMSANVMIEGTPINLGLWDTAGQEEYDRLRPLSYPETDVFLICFSLVNKDSFANVKEKWYKEVSHFSKETPIILVGTKLDLREERALNENDKNQIRSSPVTYQQGLALCQEIGAVKYIECSARTQVNLRQVFEEAIRVVINK-PKPSNPRFKFCSLL 194
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Planmine SMEST
Match: SMESG000024968.1 (SMESG000024968.1) HSP 1 Score: 221.861 bits (564), Expect = 1.638e-71 Identity = 103/191 (53.93%), Postives = 139/191 (72.77%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLRHLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPKCSLL 648 M+ IKCVVVGDG VGKTC LISYTT+ FP EY+PT+FDN+ AN+MVD +NL LWDTAGQE YD+LR Y T VF++CFS+++ ++YENV+ W E+ N+CP PIILVGTK+DLR D + + +++Y +GLIL K+I A K++ECSA ++ GL VF+E+IR V+ K+ K +CS+L Sbjct: 1 MQGIKCVVVGDGAVGKTCLLISYTTSAFPGEYIPTVFDNYSANIMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFIICFSLVNPSSYENVRAKWYPEVNNHCPNTPIILVGTKLDLR-----DESQTNKTGGHISYPQGLILMKEIGAKKYLECSALTQTGLKTVFDESIRVVLCPKQKQNKKRCSIL 186
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Planmine SMEST
Match: SMESG000005012.1 (SMESG000005012.1) HSP 1 Score: 203.371 bits (516), Expect = 2.755e-64 Identity = 95/179 (53.07%), Postives = 131/179 (73.18%), Query Frame = 1 Query: 76 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLR-HLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVIN 609 M++IKCVV+GDG VGKTC L+S+TT+ F + +PT+FDN AN+M+DG INL LWDTAGQ+ +D +RV Y T VFL+CFS++++ ++ NVK W KE+ +Y PIILVGTK+DLR + ++ S VTYQ+GL L ++I AVK++ECSAK++E L VFEEA+R V+N Sbjct: 1 MRSIKCVVIGDGAVGKTCILVSFTTDVFSSSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLN 179 The following BLAST results are available for this feature:
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Ras-like C3 botulinum toxin substrate 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30003600 ID=SMED30003600|Name=Ras-like C3 botulinum toxin substrate 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1113bpback to top protein sequence of SMED30003600-orf-1 >SMED30003600-orf-1 ID=SMED30003600-orf-1|Name=SMED30003600-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=192bp MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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