Neur_chan_LBD domain-containing protein

Overview
NameNeur_chan_LBD domain-containing protein
Smed IDSMED30003563
Length (bp)1389
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Neur_chan_LBD domain-containing protein (SMED30003563) t-SNE clustered cells

Violin plots show distribution of expression levels for Neur_chan_LBD domain-containing protein (SMED30003563) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Neur_chan_LBD domain-containing protein (SMED30003563) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Neur_chan_LBD domain-containing protein (SMED30003563) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003563

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30003563SMESG000041914.1 SmedASXL_012046SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30003563SMESG000041914.1 dd_Smed_v4_14474_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30003563SMESG000041914.1 dd_Smed_v6_14474_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30003563SMESG000041914.1 dd_Smed_v6_14474_0_1dd_Smed_v6PMID:30399335
Ross et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
neuronSMED30003563SMESG000041914.1 dd_Smed_v6_14474_0_1dd_Smed_v6PMID:30399335
Ross et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
epidermisSMED30003563SMESG000041914.1 dd_Smed_v4_14474_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 75.0998 bits (183), Expect = 6.835e-14
Identity = 60/275 (21.82%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    +K+ V  ++ ++  ++S+  H  V   ++   +  G+  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA-VTGVERIELPQFSIVEHRLVSRNVV---FATGAYPRLSLSF--RLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 75.0998 bits (183), Expect = 8.277e-14
Identity = 60/275 (21.82%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    +K+ V  ++ ++  ++S+  H  V   ++   +  G+  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:  123 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA-VTGVERIELPQFSIVEHRLVSRNVV---FATGAYPRLSLSF--RLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 388
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 74.7146 bits (182), Expect = 8.521e-14
Identity = 60/275 (21.82%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    +K+ V  ++ ++  ++S+  H  V   ++   +  G+  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   34 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA-VTGVERIELPQFSIVEHRLVSRNVV---FATGAYPRLSLSF--RLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 299
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 74.7146 bits (182), Expect = 9.257e-14
Identity = 60/275 (21.82%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    +K+ V  ++ ++  ++S+  H  V   ++   +  G+  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA-VTGVERIELPQFSIVEHRLVSRNVV---FATGAYPRLSLSF--RLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB1 (gamma-aminobutyric acid type A receptor beta1 subunit [Source:HGNC Symbol;Acc:HGNC:4081])

HSP 1 Score: 74.7146 bits (182), Expect = 1.071e-13
Identity = 58/275 (21.09%), Postives = 129/275 (46.91%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + +  ID V+EV   Y+  ++ +  W++  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F     +  V  ++ ++  ++S+ ++  V  K+   ++  G+  R  + F  R  R   YF++  +M S++  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKV---EFTTGAYPRLSLSF--RLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Match: avr-15 (pep chromosome:WBcel235:V:13498786:13502743:-1 gene:WBGene00000233.1 transcript:R11G10.1b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-15)

HSP 1 Score: 60.8474 bits (146), Expect = 9.820e-10
Identity = 68/291 (23.37%), Postives = 113/291 (38.83%), Query Frame = 1 
Query:  277 APRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLD-------QSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQ----DLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNE 1116
             P  + +  +   I KID VN  YS ++     W +  L        Q +++        W P     N     K ++ +  V      +  I    ++       + LQ++P D Q    DL+    T   I+ V   E P     V    G+ S   S F      +    +  N GS      +   R  RQF Y+L+  ++ S M  ++++ SF I  T    R++L +T LLT  T    ++  LP + Y+  +D  I     M  I C    L   W+ +++N +
Sbjct:  100 GPVVVSVNMLLRSISKIDNVNMEYSVQLTFRESWVDKRLSFGVKGDAQPDFLILTAGQEIWMPDSFFQNEKQAYKHMIDKPNVLIRVHKDGTILYSVRISLVLSCPMHLQYYPMDVQQCFIDLASYAYTTKDIEYVWKEETP-----VQLKAGLSSSLPS-FQLTNTSTTYCTSKTNTGSYSCLRTIIQLR--RQFSYYLLQLYIPSCMLVIVSWVSFWIDRTAVPARVTLGVTTLLTMTTQSSGINAKLPPVAYIKAIDVWI--GACMTFIFCA--LLEFAWVTYIANKQ 378
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Match: avr-15 (pep chromosome:WBcel235:V:13498786:13502582:-1 gene:WBGene00000233.1 transcript:R11G10.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-15)

HSP 1 Score: 60.8474 bits (146), Expect = 9.820e-10
Identity = 68/291 (23.37%), Postives = 113/291 (38.83%), Query Frame = 1 
Query:  277 APRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLD-------QSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQ----DLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNE 1116
             P  + +  +   I KID VN  YS ++     W +  L        Q +++        W P     N     K ++ +  V      +  I    ++       + LQ++P D Q    DL+    T   I+ V   E P     V    G+ S   S F      +    +  N GS      +   R  RQF Y+L+  ++ S M  ++++ SF I  T    R++L +T LLT  T    ++  LP + Y+  +D  I     M  I C    L   W+ +++N +
Sbjct:  100 GPVVVSVNMLLRSISKIDNVNMEYSVQLTFRESWVDKRLSFGVKGDAQPDFLILTAGQEIWMPDSFFQNEKQAYKHMIDKPNVLIRVHKDGTILYSVRISLVLSCPMHLQYYPMDVQQCFIDLASYAYTTKDIEYVWKEETP-----VQLKAGLSSSLPS-FQLTNTSTTYCTSKTNTGSYSCLRTIIQLR--RQFSYYLLQLYIPSCMLVIVSWVSFWIDRTAVPARVTLGVTTLLTMTTQSSGINAKLPPVAYIKAIDVWI--GACMTFIFCA--LLEFAWVTYIANKQ 378
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Match: avr-15 (pep chromosome:WBcel235:V:13498786:13511718:-1 gene:WBGene00000233.1 transcript:R11G10.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-15)

HSP 1 Score: 60.077 bits (144), Expect = 2.078e-9
Identity = 68/291 (23.37%), Postives = 113/291 (38.83%), Query Frame = 1 
Query:  277 APRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLD-------QSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQ----DLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNE 1116
             P  + +  +   I KID VN  YS ++     W +  L        Q +++        W P     N     K ++ +  V      +  I    ++       + LQ++P D Q    DL+    T   I+ V   E P     V    G+ S   S F      +    +  N GS      +   R  RQF Y+L+  ++ S M  ++++ SF I  T    R++L +T LLT  T    ++  LP + Y+  +D  I     M  I C    L   W+ +++N +
Sbjct:  279 GPVVVSVNMLLRSISKIDNVNMEYSVQLTFRESWVDKRLSFGVKGDAQPDFLILTAGQEIWMPDSFFQNEKQAYKHMIDKPNVLIRVHKDGTILYSVRISLVLSCPMHLQYYPMDVQQCFIDLASYAYTTKDIEYVWKEETP-----VQLKAGLSSSLPS-FQLTNTSTTYCTSKTNTGSYSCLRTIIQLR--RQFSYYLLQLYIPSCMLVIVSWVSFWIDRTAVPARVTLGVTTLLTMTTQSSGINAKLPPVAYIKAIDVWI--GACMTFIFCA--LLEFAWVTYIANKQ 557
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Match: glc-2 (Glutamate-gated chloride channel subunit beta [Source:UniProtKB/Swiss-Prot;Acc:Q17328])

HSP 1 Score: 55.4546 bits (132), Expect = 5.080e-8
Identity = 61/246 (24.80%), Postives = 110/246 (44.72%), Query Frame = 1 
Query:  322 KIDTVNEVYSGEIFLEAKWREPLLDQSN---YIDNQDLS------SYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVT-VATDHSIDEVKMFEC-PHNKSKVNTIDGMDSQEWSLFNHV-QVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLD 1023
            KID VN  YS ++    +W +P L   N   Y     L+      S W P           + L+  E +F     +  I    ++  T    + LQ +P D Q  +   V+  H+++++ M+E  P    ++    G D   + L N+    +     N  + G    Q++       RQF Y+L+  +  ++M  ++++ SF I + +T GR++L +T LLT  T + A++  LP + Y+  +D
Sbjct:   70 KIDVVNMEYSIQLTFREQWIDPRLAYENLGFYNPPAFLTVPHVKKSLWIPDTFFPTEKAAHRHLIDMENMFLRIYPDGKILYSSRISLTSSCPMRLQLYPLDYQSCNFDLVSYAHTMNDI-MYEWDPSTPVQLKPGVGSDLPNFILKNYTTNADCTSHTNTGSYGCLRMQLLF-----KRQFSYYLVQLYAPTTMIVIVSWVSFWIDLHSTAGRVALGVTTLLTMTTMQSAINAKLPPVSYVKVVD 309
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Match: lgc-31 (Ligand-Gated ion Channel [Source:UniProtKB/TrEMBL;Acc:G5EE87])

HSP 1 Score: 53.1434 bits (126), Expect = 3.542e-7
Identity = 68/250 (27.20%), Postives = 112/250 (44.80%), Query Frame = 1 
Query:  304 VFL-KILKIDTVNEVYSGEIFLEAKWREPLL--DQSNYIDNQDL----SSYWNPKIAI--SNIFVETKSLVSREVVFANKSGEA--YISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNH-VQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRL-----SLCMTVLLTSVTFKVAVSQNLPK 999
            VFL +I+K+D V    S     E  W +  L  + S+Y   +++    S  W P+ ++  S  F +   L S   V  N +G+   YI    +        L+++ FPFD Q  S+   +  HS D +K      N   ++ ID  D+QEW L  H   V S   L DY       ++I+ T    RQ  Y++ N  + S+M  L++    G    +T GR+      L +  L++     +A+ +++PK
Sbjct:  159 VFLYQIVKLDAVKNTISLSGSFELYWEDEFLKWNPSSYEGAEEIFLSSSDIWIPEFSLYYSLNFNDAVKLQSNNDVRVNYTGQVRYYIPFSSESLCK----LDVKFFPFDVQQCSLLFGSWAHSNDSIKYSLYSQN---LSLIDFYDNQEWELDTHNSSVHSDGFLYDYLDPPLFWEMIIITLVMKRQSFYYVFNLVIPSTMITLVSV--IGFHTPSTSGRMRDAKFRLGIMTLMSMSVILLAIVEDMPK 399
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: CG8916 (gene:FBgn0030707 transcript:FBtr0301233)

HSP 1 Score: 61.2326 bits (147), Expect = 1.085e-9
Identity = 56/248 (22.58%), Postives = 108/248 (43.55%), Query Frame = 1 
Query:  346 YSGEIFLEAKWREPLLDQSNYIDNQDLS-----SYWNPKIAISNIFVETKSL--VSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCI 1068
            YS + +    WR+  L     I +  LS       W P     N       +  V  +++  +++G    S +  ++AT    +ELQ+FP D Q   + + +   I++  ++E  +    V+ + GM   ++ L + +      +  + +       ++       R   YFLI  ++   +  +L++ SF I    T  R+SLC+T +LT  T  +    +LPK+ Y T LD  +L + +  + T +
Sbjct:   52 YSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATC--PMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRREGDF-----SVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLL 292
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: CG8916 (gene:FBgn0030707 transcript:FBtr0301232)

HSP 1 Score: 60.4622 bits (145), Expect = 1.836e-9
Identity = 58/251 (23.11%), Postives = 110/251 (43.82%), Query Frame = 1 
Query:  346 YSGEIFLEAKWREPLLDQSNYIDNQDLS-----SYWNPKIAI-----SNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCI 1068
            YS + +    WR+  L     I +  LS       W P         S I + T   V  +++  +++G    S +  ++AT    +ELQ+FP D Q   + + +   I++  ++E  +    V+ + GM   ++ L + +      +  + +       ++       R   YFLI  ++   +  +L++ SF I    T  R+SLC+T +LT  T  +    +LPK+ Y T LD  +L + +  + T +
Sbjct:  154 YSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMIT---VPNKLLRLDQNGGILYSMRLTIKATC--PMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRREGDF-----SVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLL 394
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: HisCl1 (gene:FBgn0037950 transcript:FBtr0082470)

HSP 1 Score: 59.6918 bits (143), Expect = 2.862e-9
Identity = 61/263 (23.19%), Postives = 115/263 (43.73%), Query Frame = 1 
Query:  280 PRQIYLKCVFLKILKIDTVNE---VYSGEIFLEAKWREPLL-------DQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEK----RKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLD 1023
            P  +Y     + +L +D++NE    Y  +IFL   WR+P L       +Q   +D   L S W P       F   K +   E+   N     Y  +      K+       ++ + +P D Q  S+ + +  H+++++       +   VNT   ++  +  + N+   +  I   +Y+ G+     IVF  R  R+  Y L + ++ S++  ++++ SF I+      R++L +T LLT  T      Q+LP + Y+  +D
Sbjct:   79 PTVVYFH---VTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVDWLHSIWRPDC----FFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLVVNT--EIELPQLDISNNYTTDCTI---EYSTGNFTCLAIVFNLR--RRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAID 327
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: HisCl1 (gene:FBgn0037950 transcript:FBtr0082471)

HSP 1 Score: 59.3066 bits (142), Expect = 3.095e-9
Identity = 61/263 (23.19%), Postives = 115/263 (43.73%), Query Frame = 1 
Query:  280 PRQIYLKCVFLKILKIDTVNE---VYSGEIFLEAKWREPLL-------DQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEK----RKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLD 1023
            P  +Y     + +L +D++NE    Y  +IFL   WR+P L       +Q   +D   L S W P       F   K +   E+   N     Y  +      K+       ++ + +P D Q  S+ + +  H+++++       +   VNT   ++  +  + N+   +  I   +Y+ G+     IVF  R  R+  Y L + ++ S++  ++++ SF I+      R++L +T LLT  T      Q+LP + Y+  +D
Sbjct:   79 PTVVYFH---VTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVDWLHSIWRPDC----FFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLVVNT--EIELPQLDISNNYTTDCTI---EYSTGNFTCLAIVFNLR--RRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAID 327
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: CG6927 (gene:FBgn0029733 transcript:FBtr0070721)

HSP 1 Score: 53.1434 bits (126), Expect = 3.973e-7
Identity = 54/234 (23.08%), Postives = 102/234 (43.59%), Query Frame = 1 
Query:  364 LEAKWREPLLDQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKI--ILNDYNIGS--KERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMI 1053
            +  K R+P+L + +  +     S W P I ++N    +   ++ + +  + S +  +    +++AT    L L+ FPFD Q  S TV      +  ++      K  +     +   E+ L      E+ I   L+D   G+       + FT    R   ++L++ F+ S +   +++ SF +Q      R++L  + LLT +T   A  + LPK+ Y+   +   LG  I I
Sbjct:  108 VSPKRRQPILGEEHLRN-----SLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHCS-TVLESWMYNTSELVLHWEQKRPITYDGALHLTEFVLQRSWSNETVINADLSDLRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITLASAQGKTLPKVSYIKVSEVWFLGCTIFI 335
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrb1 (gamma-aminobutyric acid type A receptor beta1 subunit [Source:ZFIN;Acc:ZDB-GENE-090313-230])

HSP 1 Score: 79.7221 bits (195), Expect = 1.479e-15
Identity = 63/293 (21.50%), Postives = 134/293 (45.73%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF----HLSNNEATTALKN 1137
            + I  ID V+EV   Y+  ++ +  WR+  L  +       +DN+     W P       F+  K      V   N+      +  +    ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +      S V  +D ++  ++S+ ++  +  K++   +  GS  R  + F  +  R   YF++  +M S++  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F    HL    A  A K+
Sbjct:   75 IDISSIDMVSEVNMDYTITMYFQQSWRDKRLSYTGIPLNLTLDNRVADQLWVP----DTYFINDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--QGGSSVTGVDNIELPQFSIIDYKTLSKKVV---FATGSYPRLSLSFKLK--RNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGRGPHLQKKVAEKAAKS 356
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrb4 (gamma-aminobutyric acid type A receptor beta4 subunit [Source:ZFIN;Acc:ZDB-GENE-070424-211])

HSP 1 Score: 72.4034 bits (176), Expect = 3.107e-13
Identity = 60/276 (21.74%), Postives = 123/276 (44.57%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID+++EV   Y+  ++ +  WR+  L  +       +DN+     W P       F+  K      V   N+      +  +    ++  T    ++L+ +P D Q+ ++ + +  ++ D++  F     +   N + G+D  E   F+ V++        +  GS  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   68 INIASIDSISEVNMDYTITMYFQQSWRDKRLAYAEMALNLTLDNRVADQLWLP----DTYFLNDKKSFLHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIVFFW----QGGDNAVTGVDKLELPQFSIVELRLVSREVRFTTGSYPRLSLSF--RIKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGVTTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYVFF 333
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrb4 (gamma-aminobutyric acid type A receptor beta4 subunit [Source:ZFIN;Acc:ZDB-GENE-070424-211])

HSP 1 Score: 72.0182 bits (175), Expect = 4.349e-13
Identity = 60/276 (21.74%), Postives = 123/276 (44.57%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID+++EV   Y+  ++ +  WR+  L  +       +DN+     W P       F+  K      V   N+      +  +    ++  T    ++L+ +P D Q+ ++ + +  ++ D++  F     +   N + G+D  E   F+ V++        +  GS  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   68 INIASIDSISEVNMDYTITMYFQQSWRDKRLAYAEMALNLTLDNRVADQLWLP----DTYFLNDKKSFLHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIVFFW----QGGDNAVTGVDKLELPQFSIVELRLVSREVRFTTGSYPRLSLSF--RIKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGVTTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYVFF 333
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrb3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:ZFIN;Acc:ZDB-GENE-101102-2])

HSP 1 Score: 69.707 bits (169), Expect = 2.713e-12
Identity = 56/275 (20.36%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + +  ID V+EV   Y+  ++ +  WR+  L  +       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F     ++ V  +  ++  ++S+ ++  V   ++   ++ G+  R  + F  +  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDVASIDMVSEVNMDYTLTMYFQQYWRDKRLAYTGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWKGGETAVTGVSRIELPQFSIVDYKLVSRNVV---FSTGAYPRLSLSFKLK--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrb3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:ZFIN;Acc:ZDB-GENE-101102-2])

HSP 1 Score: 69.707 bits (169), Expect = 2.713e-12
Identity = 56/275 (20.36%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + +  ID V+EV   Y+  ++ +  WR+  L  +       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F     ++ V  +  ++  ++S+ ++  V   ++   ++ G+  R  + F  +  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDVASIDMVSEVNMDYTLTMYFQQYWRDKRLAYTGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWKGGETAVTGVSRIELPQFSIVDYKLVSRNVV---FSTGAYPRLSLSFKLK--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000004017.1 (gamma-aminobutyric acid (GABA) A receptor, beta 1 [Source:NCBI gene;Acc:100489344])

HSP 1 Score: 77.7962 bits (190), Expect = 8.329e-15
Identity = 59/275 (21.45%), Postives = 131/275 (47.64%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + +  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D++K +    +K+ +  ++ ++  ++S+ ++  V   +I   ++ G+  R  + F  R  R   YF++  +M S++  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDVASIDMVSEVNMDYTLTMYFQQSWRDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKRSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIKFYWNGGDKA-ITGVEKIELPQFSIIDYKMVSRNVI---FSTGAYPRLSLSF--RLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000020832.1 (gamma-aminobutyric acid type A receptor theta subunit [Source:NCBI gene;Acc:100496398])

HSP 1 Score: 75.8702 bits (185), Expect = 4.222e-14
Identity = 58/276 (21.01%), Postives = 125/276 (45.29%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID ++EV   Y+  ++ +  WR+  L  +       +DN+     W P       F+  K      V   N+      +  +    ++  T    ++L+ +P D Q+ ++ + +  ++ID++K F     ++ V  +  ++  ++++     V   ++   +  GS  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   72 IHISSIDQISEVNMDYTITMYFQQSWRDKRLAYTALPLNLTLDNRVADQLWLP----DTYFLNDKKSFLHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDQQNCTLEIESYGYTIDDIKFFWQGGEEAAVTGVSALELPQFTIIETRLVSKNVV---FTTGSYPRLSLSF--RIKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGVTTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYVFF 338
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000020814.1 (gamma-aminobutyric acid type A receptor theta subunit [Source:NCBI gene;Acc:100496398])

HSP 1 Score: 75.485 bits (184), Expect = 4.480e-14
Identity = 58/276 (21.01%), Postives = 125/276 (45.29%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID ++EV   Y+  ++ +  WR+  L  +       +DN+     W P       F+  K      V   N+      +  +    ++  T    ++L+ +P D Q+ ++ + +  ++ID++K F     ++ V  +  ++  ++++     V   ++   +  GS  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   55 IHISSIDQISEVNMDYTITMYFQQSWRDKRLAYTALPLNLTLDNRVADQLWLP----DTYFLNDKKSFLHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDQQNCTLEIESYGYTIDDIKFFWQGGEEAAVTGVSALELPQFTIIETRLVSKNVV---FTTGSYPRLSLSF--RIKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGVTTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYVFF 321
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Match: gabrb2 (gamma-aminobutyric acid (GABA) A receptor, beta 2 [Source:NCBI gene;Acc:100125027])

HSP 1 Score: 73.9442 bits (180), Expect = 1.259e-13
Identity = 60/275 (21.82%), Postives = 129/275 (46.91%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D++  +    N + V  ++ ++  ++S+ ++  +   ++   ++ GS  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +AL +   F
Sbjct:   49 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIGFYWRGGNNA-VTGVERLELPQFSIIDYNLLSRNVV---FSTGSYPRLSLSFKLR--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFF 314
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Match: gabrb2 (gamma-aminobutyric acid (GABA) A receptor, beta 2 [Source:NCBI gene;Acc:100125027])

HSP 1 Score: 73.9442 bits (180), Expect = 1.314e-13
Identity = 60/275 (21.82%), Postives = 129/275 (46.91%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D++  +    N + V  ++ ++  ++S+ ++  +   ++   ++ GS  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +AL +   F
Sbjct:   43 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIGFYWRGGNNA-VTGVERLELPQFSIIDYNLLSRNVV---FSTGSYPRLSLSFKLR--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFF 308
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Gabrb3 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 [Source:MGI Symbol;Acc:MGI:95621])

HSP 1 Score: 75.0998 bits (183), Expect = 5.413e-14
Identity = 60/275 (21.82%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    +K+ V  ++ ++  ++S+  H  V   ++   +  G+  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA-VTGVERIELPQFSIVEHRLVSRNVV---FATGAYPRLSLSF--RLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Gabrb3 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 [Source:MGI Symbol;Acc:MGI:95621])

HSP 1 Score: 74.7146 bits (182), Expect = 5.957e-14
Identity = 60/275 (21.82%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    +K+ V  ++ ++  ++S+  H  V   ++   +  G+  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   89 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA-VTGVERIELPQFSIVEHRLVSRNVV---FATGAYPRLSLSF--RLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 354
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Gabrb3 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 [Source:MGI Symbol;Acc:MGI:95621])

HSP 1 Score: 74.3294 bits (181), Expect = 7.396e-14
Identity = 60/275 (21.82%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    +K+ V  ++ ++  ++S+  H  V   ++   +  G+  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA-VTGVERIELPQFSIVEHRLVSRNVV---FATGAYPRLSLSF--RLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Gabrb1 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 [Source:MGI Symbol;Acc:MGI:95619])

HSP 1 Score: 74.3294 bits (181), Expect = 7.417e-14
Identity = 58/275 (21.09%), Postives = 129/275 (46.91%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + +  ID V+EV   Y+  ++ +  W++  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F     +  V  ++ ++  ++S+ ++  V  K+   ++  G+  R  + F  R  R   YF++  +M S++  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKV---EFTTGAYPRLSLSF--RLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Gabrb2 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 [Source:MGI Symbol;Acc:MGI:95620])

HSP 1 Score: 72.0182 bits (175), Expect = 4.325e-13
Identity = 60/276 (21.74%), Postives = 131/276 (47.46%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  +       +DN+     W P     N   + KS V   V   N+      +  +    ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F    + + V  +  ++  ++S+ ++  +  K++   ++ GS  R  + F  +  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +AL +   F
Sbjct:   66 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN---DKKSFV-HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVV---FSTGSYPRLSLSFKLK--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFF 331
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P28472|GBRB3_HUMAN (Gamma-aminobutyric acid receptor subunit beta-3 OS=Homo sapiens OX=9606 GN=GABRB3 PE=1 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 3.282e-13
Identity = 60/275 (21.82%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    +K+ V  ++ ++  ++S+  H  V   ++   +  G+  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA-VTGVERIELPQFSIVEHRLVSRNVV---FATGAYPRLSLSF--RLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P63079|GBRB3_RAT (Gamma-aminobutyric acid receptor subunit beta-3 OS=Rattus norvegicus OX=10116 GN=Gabrb3 PE=1 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 3.786e-13
Identity = 60/275 (21.82%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    +K+ V  ++ ++  ++S+  H  V   ++   +  G+  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA-VTGVERIELPQFSIVEHRLVSRNVV---FATGAYPRLSLSF--RLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P63080|GBRB3_MOUSE (Gamma-aminobutyric acid receptor subunit beta-3 OS=Mus musculus OX=10090 GN=Gabrb3 PE=1 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 3.786e-13
Identity = 60/275 (21.82%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    +K+ V  ++ ++  ++S+  H  V   ++   +  G+  R  + F  R  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA-VTGVERIELPQFSIVEHRLVSRNVV---FATGAYPRLSLSF--RLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P08220|GBRB1_BOVIN (Gamma-aminobutyric acid receptor subunit beta-1 OS=Bos taurus OX=9913 GN=GABRB1 PE=1 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 4.704e-13
Identity = 58/275 (21.09%), Postives = 129/275 (46.91%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + +  ID V+EV   Y+  ++ +  W++  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F     +  V  ++ ++  ++S+ ++  V  K+   ++  G+  R  + F  R  R   YF++  +M S++  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKV---EFTTGAYPRLSLSF--RLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P15431|GBRB1_RAT (Gamma-aminobutyric acid receptor subunit beta-1 OS=Rattus norvegicus OX=10116 GN=Gabrb1 PE=1 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 5.097e-13
Identity = 58/275 (21.09%), Postives = 129/275 (46.91%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + +  ID V+EV   Y+  ++ +  W++  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F     +  V  ++ ++  ++S+ ++  V  K+   ++  G+  R  + F  R  R   YF++  +M S++  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKV---EFTTGAYPRLSLSF--RLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A4E0RSR9 (Uncharacterized protein OS=Fasciola hepatica OX=6192 GN=D915_005714 PE=4 SV=1)

HSP 1 Score: 240.736 bits (613), Expect = 2.691e-71
Identity = 152/366 (41.53%), Postives = 213/366 (58.20%), Query Frame = 1 
Query:  304 VFLKILKIDTVNEVYSGEIFLEAKWREPLLD--------QSNY-----IDN--QDL-------------SSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQ--IIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNIESXXXXXXXXXXXXXXXXXXXXXXFDAGKRRREMKGKDIEFNRALDKILMAKSSCDI 1311
            +F+KI ++DTVNE Y  +IFL+A+WREPLLD        Q N+     ++N  QDL               +WNP++ + N   E   +VS EV F   + EAY+ EKR+++  F ETLEL+HFPFD QDLSVTV  D S+DEV +   P   S+V+     DSQEW +F+HV VE   I   Y+ G+ +R+   +VFT R+AR+  YF++N  +IS +  LL+F  F + V     RL   + +LLT+VTFK A SQNLPKI YLTYLDK +L N  M++I  +WH +        S + +   L + E  ++  +L  Y +  +IFGL +Y DAG RRR M+ KD+EF +   +I   K    I
Sbjct:    3 IFVKIGQVDTVNERYQADIFLQARWREPLLDATWKSERAQKNWRGKSGVENPIQDLVPKRHLHTLGLQDDEFWNPRLLLDNAQGEPIEIVSHEVEFVEPTFEAYLVEKRRIKGVFHETLELKHFPFDVQDLSVTVTCDRSVDEVLLVPSPTEVSQVDRRGAADSQEWKIFHHVDVERMEIQTAYSPGTSKRRHPGLVFTSRSARRSGYFMVNMVLISCVLCLLSFCIFSVPVDG--NRLQQALLLLLTTVTFKFAASQNLPKISYLTYLDKVVLANFFMLVILTVWHTIAR------SLSASYPKLLDNEKYVVYTLLSSYCLGAVIFGLTVYLDAGSRRRLMQRKDVEFGQLKTRIEREKQRTSI 360
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A3R7CFX9 (Neuronal acetylcholine receptor subunit alpha-7 OS=Clonorchis sinensis OX=79923 GN=CHRNA7 PE=4 SV=1)

HSP 1 Score: 241.506 bits (615), Expect = 3.038e-71
Identity = 148/368 (40.22%), Postives = 215/368 (58.42%), Query Frame = 1 
Query:  286 QIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQS-------------NYIDN----------------QDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQ--IIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNIESXXXXXXXXXXXXXXXXXXXXXXFDAGKRRREMKGKDIEFNRALDKILMAK 1296
            ++ L  +F+KI ++DTVNE Y  +IFL+A+WREPLLD +               ++N                QD   +WNP++ + N   E   +VS EV F     EAY+ EKR+++  F ETLEL+HFPFDCQDLSVTV  D +++EV++   P   S+V+     DSQEW +F+HV + S  I   Y+ G+ +R+   +VFT R+AR+  YF++N  +IS +  LL+F+ F + V     RL L + +LLT+VTFK A SQNLPKI YLTYLDK +L N  M++I  +WH +        S       LK+ E  ++  +L  Y +  ++FGL +Y DAG RRR MK KD++F +   +I + K
Sbjct:   38 RVELMLIFVKIGQVDTVNERYQADIFLQARWREPLLDATWNTSRPRNNFRTFKMVENPVMELAPKRHLHTLKLQD-DEFWNPRLLLDNAQGEPIEIVSHEVEFVEPDFEAYLVEKRRIKGVFHETLELKHFPFDCQDLSVTVTCDRTVEEVELVPSPTEVSQVDRRCAADSQEWKIFHHVDIASMEIQTAYSPGTCKRRHPGLVFTSRSARRAGYFMVNMALISCVLSLLSFSVFSVPVDG--NRLQLSLLLLLTTVTFKFAASQNLPKISYLTYLDKMVLANFFMLVILTVWHTIAR------SVFAKYPGLKDKEQYVVYTLLSAYCLGAVVFGLTVYLDAGSRRRLMKSKDMDFTQHKQRIELEK 396
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A075A8W6 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_08254 PE=3 SV=1)

HSP 1 Score: 246.128 bits (627), Expect = 6.070e-71
Identity = 151/371 (40.70%), Postives = 218/371 (58.76%), Query Frame = 1 
Query:  277 APRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQS-------------NYIDN----------------QDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQI--IVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNIESXXXXXXXXXXXXXXXXXXXXXXFDAGKRRREMKGKDIEFNRALDKILMAK 1296
             P ++ L  +F+KI ++DTVNE Y  +IFL+A+WREPLLD +             N ++N                QD   +WNP++ + N   E   +VS EV F     EAY+ EKR+++  F ETLEL+HFPFDCQDLSVTV  D +++EV++   P   S+V+     DSQEW +F+HV + S  I   Y+ G+ +R+   +VFT R+AR+  YF++N  +IS +  LL+F+ F + V     RL L + +LLT+VTFK A SQNLPKI YLTYLDK +L N  M++I  +WH +        S       LK+ E  ++  +L  Y +  ++FGL +Y DAG RRR MK KD++F +   +I +AK
Sbjct:  235 PPARVELMLIFVKIGQVDTVNERYQADIFLQARWREPLLDATWNTSRPRNNFRTFNMVENPVMELAPKRHLHTLKLQD-DEFWNPRLLLDNAQGEPIEIVSHEVEFVEPDFEAYLVEKRRIKGIFHETLELKHFPFDCQDLSVTVTCDRTVEEVELVPSPTEVSQVDRRCAADSQEWKIFHHVDIASMEIQTAYSPGTCKRRHPGLVFTSRSARRAGYFMVNMALISCVLSLLSFSVFSVPVDG--NRLQLSLLLLLTTVTFKFAASQNLPKISYLTYLDKMVLANFFMLVILTVWHTIAR------SVFAKYPGLKDKEQYVVYTLLSAYCLGAVVFGLTVYLDAGSRRRLMKSKDMDFTQHKQRIELAK 596
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BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A5K4FCR6 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 238.039 bits (606), Expect = 1.426e-67
Identity = 156/378 (41.27%), Postives = 220/378 (58.20%), Query Frame = 1 
Query:  286 QIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLD--------------QSN-YIDNQ--DLSS-------------YWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQI--IVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALK----NIESXXXXXXXXXXXXXXXXXXXXXXFDAGKRRREMKGKDIEFNRALDKILMAKSSCDI 1311
            ++ L  +F+K+ ++DTVNE Y  +IFL+A+WREPLLD              Q+N  I+N   DL+S             +WNP++ I N   E   ++S EV F     EAY+ EKR+++  F ETLEL+HFPFDCQDLSVT+  D + DEV++   P   S+V+     DSQEW +F+HV ++S  I   Y+  + +R    +VFT R+AR+  YFL+N  +IS +  LL+F++F +       RL L + +LLT+VTFK A SQNLPKI YLTYLDK +L N  M++I  +WHA+            A +A K      E  ++ ++L  Y I  ++FGL +Y DAG RRR MK KDIEFN+   +I   K    I
Sbjct:  275 RVELVLIFVKVGQVDTVNERYQADIFLQARWREPLLDAMWNKSSLKSKSSWQTNPSIENPFTDLTSKRQLNTLKLQDDEFWNPRLLIDNAEGEPIEIISHEVEFIEPDFEAYLVEKRRIKGIFHETLELRHFPFDCQDLSVTITCDRTTDEVELVASPTEVSQVDVRCAADSQEWKIFHHVDIKSIEIQTGYSPSTSKRHHPGLVFTSRSARRSGYFLVNMILISCVLCLLSFSAFSVPANE--NRLQLSLLLLLTTVTFKFAASQNLPKISYLTYLDKVVLVNFFMLVILTVWHAIA----------RAVSASKPKFLEYEHYVMYSLLSCYCIGSVLFGLTVYLDAGSRRRLMKRKDIEFNQYKQQIEAEKQQHSI 640
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A2H1C9P4 (Uncharacterized protein OS=Fasciola hepatica OX=6192 GN=D915_08727 PE=4 SV=1)

HSP 1 Score: 231.491 bits (589), Expect = 1.872e-67
Identity = 153/385 (39.74%), Postives = 214/385 (55.58%), Query Frame = 1 
Query:  304 VFLKILKIDTVNEVYSGEIFLEAKWREPLLD--------QSNY-----IDN--QDL-------------SSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHV-------------------QVESKIILNDYNIGSKERQ--IIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNIESXXXXXXXXXXXXXXXXXXXXXXFDAGKRRREMKGKDIEFNRALDKILMAKSSCDI 1311
            +F+KI ++DTVNE Y  +IFL+A+WREPLLD        Q N+     ++N  QDL               +WNP++ + N   E   +VS EV F   + EAY+ EKR+++  F ETLEL+HFPFD QDLSVTV  D S+DEV +   P   S+V+     DSQEW +F+HV                   QVE   I   Y+ G+ +R+   +VFT R+AR+  YF++N  +IS +  LL+F  F + V     RL   + +LLT+VTFK A SQNLPKI YLTYLDK +L N  M++I  +WH +        S + +   L + E  ++  +L  Y +  +IFGL +Y DAG RRR M+ KD+EF +   +I   K    I
Sbjct:    3 IFVKIGQVDTVNERYQADIFLQARWREPLLDATWKSERAQKNWRGKSGVENPIQDLVPKRHLHTLGLQDDEFWNPRLLLDNAQGEPIEIVSHEVEFVEPTFEAYLVEKRRIKGVFHETLELKHFPFDVQDLSVTVTCDRSVDEVLLVPSPTEVSQVDRRGAADSQEWKIFHHVDFFRCLPTFPPRPPPRPLAQVERMEIQTAYSPGTSKRRHPGLVFTSRSARRSGYFMVNMVLISCVLCLLSFCIFSVPVDG--NRLQQALLLLLTTVTFKFAASQNLPKISYLTYLDKVVLANFFMLVILTVWHTIAR------SLSASYPKLLDNEKYVVYTLLSSYCLGAVIFGLTVYLDAGSRRRLMQRKDVEFGQLKTRIEREKQRTSI 379
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: gabrb1 (gamma-aminobutyric acid type A receptor beta1 subunit [Source:ZFIN;Acc:ZDB-GENE-090313-230])

HSP 1 Score: 78.9518 bits (193), Expect = 2.207e-15
Identity = 63/293 (21.50%), Postives = 134/293 (45.73%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF----HLSNNEATTALKN 1137
            + I  ID V+EV   Y+  ++ +  WR+  L  +       +DN+     W P       F+  K      V   N+      +  +    ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +      S V  +D ++  ++S+ ++  +  K++   +  GS  R  + F  +  R   YF++  +M S++  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F    HL    A  A K+
Sbjct:   53 IDISSIDMVSEVNMDYTITMYFQQSWRDKRLSYTGIPLNLTLDNRVADQLWVP----DTYFINDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--QEGSSVTGVDNIELPQFSIIDYKTLSKKVV---FATGSYPRLSLSFKLK--RNIGYFILQTYMPSNLITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGRGPHLQKKVAEKAAKS 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: GABRB2 (gamma-aminobutyric acid receptor subunit beta-2 [Source:NCBI gene;Acc:103038806])

HSP 1 Score: 73.559 bits (179), Expect = 1.083e-13
Identity = 58/275 (21.09%), Postives = 130/275 (47.27%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    N + V  ++ ++  ++S+ ++  +   ++   ++ G+  R  + F  +  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +AL +   F
Sbjct:   68 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGNHA-VTGVERIELPQFSIVDYKLISKNVV---FSTGAYPRLSLSFKLK--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYALVNYIFF 333
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: GABRB2 (gamma-aminobutyric acid receptor subunit beta-2 [Source:NCBI gene;Acc:103038806])

HSP 1 Score: 73.559 bits (179), Expect = 1.336e-13
Identity = 58/275 (21.09%), Postives = 130/275 (47.27%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ +    N + V  ++ ++  ++S+ ++  +   ++   ++ G+  R  + F  +  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +AL +   F
Sbjct:   68 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGNHA-VTGVERIELPQFSIVDYKLISKNVV---FSTGAYPRLSLSFKLK--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYALVNYIFF 333
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: gabrb2a (gamma-aminobutyric acid type A receptor beta2 subunit [Source:NCBI gene;Acc:103045154])

HSP 1 Score: 72.4034 bits (176), Expect = 2.748e-13
Identity = 58/275 (21.09%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F        V+ ++ ++  ++S+ ++  +   ++   ++ GS  R  + F  +  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   65 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWRGGDGAVSGVERIELPQFSIVDYKLISKNVV---FSTGSYPRLSLSFKLK--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 330
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: gabrb2a (gamma-aminobutyric acid type A receptor beta2 subunit [Source:NCBI gene;Acc:103045154])

HSP 1 Score: 72.4034 bits (176), Expect = 2.810e-13
Identity = 58/275 (21.09%), Postives = 128/275 (46.55%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F        V+ ++ ++  ++S+ ++  +   ++   ++ GS  R  + F  +  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   65 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWRGGDGAVSGVERIELPQFSIVDYKLISKNVV---FSTGSYPRLSLSFKLK--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 330
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Sea Lamprey
Match: gabrb3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:ZFIN;Acc:ZDB-GENE-101102-2])

HSP 1 Score: 60.4622 bits (145), Expect = 2.128e-10
Identity = 40/190 (21.05%), Postives = 89/190 (46.84%), Query Frame = 1 
Query:  574 LELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNI 1140
            ++L+ +P D    ++ + +  ++ +++K F      + +  +  +   ++++  H QV   +    +  GS  R  + F  R  R   YF++  +M + +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G    + +  + +A  +   F      A  A + I
Sbjct:    2 MDLRRYPLDEPFCTLEIESYGYTTEDIK-FYWRGGDTAITGVGEIKLPQFTIVKHNQVSRNV---QFATGSYPRLSLSF--RLKRNIGYFILQTYMPTILITILSWVSFWINYDASAARVALGVTTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFCFVFLALLEYAAVNYLFFGRGPQRAKKAAERI 185
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008467.1 (pep scaffold:Pmarinus_7.0:GL477211:8305:20106:1 gene:ENSPMAG00000007648.1 transcript:ENSPMAT00000008467.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.8474 bits (146), Expect = 2.774e-10
Identity = 59/263 (22.43%), Postives = 110/263 (41.83%), Query Frame = 1 
Query:  346 YSGEIFLEAKWREPLLDQSNY------IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAA-----RQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSL 1089
            Y   ++L  +W +P L  S+Y      +D  ++   W P +   N     KS    E+   NK    +    +    ++  T    ++L +FP D Q  S+ + +        +F   +  + V+  +G+   ++ L N +   S      Y+ GS       FTC  A     R+  ++LI  ++ S +  +L++ SF I +     R++L +T +LT  T       +LPK+ Y+  +D        + M TC+     +L
Sbjct:   90 YRMTVYLRQRWTDPRLAYSHYPVPLLHLDQSNIKHIWKPDLFFDN----EKSAHFHEITTDNKMLRIANNGVVDYAMRLTLTLSCPMDLHNFPMDTQMCSMYLESFGYTTADIVFHW-NGPTPVSLFEGLTLPQFVLSNKISTGS--CTKTYSTGS-------FTCIFAKFTLHREMGFYLIQLYVPSILIVILSWVSFWINMEAAPARVALGITTVLTLTTQSTGARASLPKVSYIKAMD--------IWMATCLLFVFAAL 330
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Sea Lamprey
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1])

HSP 1 Score: 58.151 bits (139), Expect = 1.757e-9
Identity = 64/269 (23.79%), Postives = 114/269 (42.38%), Query Frame = 1 
Query:  346 YSGEIFLEAKWREPLLDQSNY------IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKS----GEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIIL--NDYNIGSKERQIIVFTC-----RAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            Y   IFL  +W +P L  S Y      +D   L S W P +     F   K     EV   NK      +  +    ++  T    ++L++FP D Q  ++ + +  ++++++ +FE    +  V   +G+   ++ L    + E  ++     YN G        FTC        RQ  Y+LI  ++ S +  +L++ SF I +     R++L +T +LT  T       +LPK+ Y+  +D              IW A+  L++F
Sbjct:   27 YRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDL----FFANEKGANFHEVTTDNKLLRIFKDGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDL-IFEW-KQEGAVQVAEGLTLPQFVL----KDEKDLVYCTKHYNTGK-------FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAID--------------IWMAVCLLFVF 264
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Sea Lamprey
Match: gabrb3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:ZFIN;Acc:ZDB-GENE-101102-2])

HSP 1 Score: 56.225 bits (134), Expect = 4.964e-9
Identity = 36/156 (23.08%), Postives = 77/156 (49.36%), Query Frame = 1 
Query:  631 DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
             +++D++  F      + V  +  ++  ++S+     V + ++   +  GS  R  + F  R  R   YF++  +M S++  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G    + +  + +AL +   F
Sbjct:    1 GYTMDDIG-FYWRGGDAAVTGVSEIELPQFSIMEFRLVSTLVV---FATGSYPRLSLSF--RLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFCFVFLALLEYALVNYIFF 150
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO32790 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU26])

HSP 1 Score: 112.079 bits (279), Expect = 3.560e-27
Identity = 77/267 (28.84%), Postives = 132/267 (49.44%), Query Frame = 1 
Query:  289 IYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLL----DQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDS-QEWSLFNHVQVESKIILNDYNIGSKERQIIVF--TCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCI 1068
            + ++C    +  ID + + ++ E+++ A WREP L    ++    DN+     W+PKI+ SN  +  +    R + +   S      E  K+R TF+E   L+ FP D Q+LS+ +++D S D    FE    K          S ++W L+ HV  ++     +  +G  +R   V+  T    R+  ++  N  ++ S+   L+F SF I    T  RL++ + +LL SV +K   S +LP+  YLT+LDK  LGN++ I    +
Sbjct:   18 VLIRCGISFLGDIDVIRQQFTCELWMTASWREPKLAGKKNEEVKWDNE-----WSPKISFSNSLLLDRVYKGRRLYYEENSTVPLAQEVYKIRGTFKEQFSLEQFPVDLQELSIIISSDWS-DRTVTFEKDMAKPDYLRQQTFSSPRDWVLYPHVHTDTATQEGE-GLGPNDRSYPVYIITAHVRRRAVHYFWNTAVVMSVLTALSFASFAIPPQQTADRLTVTLLLLLISVAYKFVTSLHLPRTSYLTFLDKYQLGNLLFISFIAV 277
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO37396 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFV7])

HSP 1 Score: 63.1586 bits (152), Expect = 7.462e-11
Identity = 60/269 (22.30%), Postives = 121/269 (44.98%), Query Frame = 1 
Query:  310 LKILKIDTVNEVYSGEIFLEAKWREPLLD----QSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMD--------SQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCI 1068
            L +  ID VN  ++ ++FL  +W +P LD    ++ Y+ ++ +   W P     + F+  K+     V   N+    +    +    +V      T++L+ FP D Q+  + V   +  D   +        + N  DG+           ++SL   V++      + Y IG+    + VF+    R + YFL + +  S +   +++  F I    T  R+++ +T LLT VT    ++ ++PK+ Y+  +DK ++  +I + ++ I
Sbjct:   68 LSVDSIDVVNMDFTVDLFLRQEWVDPRLDHGLNETIYLGHRVMQKIWTP----DSYFLNAKTAKMHHVTTPNQMTLIAPMGVVKYNTRVTVKAACTIDLRSFPMDQQNCPL-VLESYGYDRSHIVY----HWEGNATDGLPFVPNRMRIMPQYSL---VRLTLSREWHQYIIGNFSAVVAVFSIE--RSYTYFLTHVYGTSCVIVFISWMGFVIPPDQTAARIAVGVTTLLTQVTVINILNSSMPKVSYVKSIDKFLISCLIFVFLSLI 322
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO40009 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8L9])

HSP 1 Score: 60.4622 bits (145), Expect = 2.328e-10
Identity = 56/260 (21.54%), Postives = 121/260 (46.54%), Query Frame = 1 
Query:  346 YSGEIFLEAKWREPLLDQSNYID------NQDL-SSYWNPKIAISNIFVETKSLVSRE-----VVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEV--KMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHAL 1080
            YS  +++  +W +P L   +          QD+ S  W P   I N   + +S+ +        +  +++G    S ++ +    Q  ++L++FP D Q     + +   ++ +V  K  + P  K+ + T +G+D+ E+S+ +   +E+  + N  N  S   +I +      R+  Y++I  ++  SM  +L++ SF +   +   R +L +T +L   T    +  +LP +PY+  +D+      +++   C++ AL
Sbjct:    3 YSMTLYMRQRWLDPRLAYGDMFPEDFITLGQDMVSQIWTPDTYIVN---KKQSMTNSGQGMSMFIRISRNGSVIFSAEKTLVIVCQ--MDLRNFPMDEQQCDFKIESYGFTMKDVVYKWLDDPKQKT-IETAEGLDATEFSIVSLKPMENISVFNLGNFSSLTMRIYL-----DRRTTYYVIQIYIPCSMIVMLSWISFWLDYKSVPARTALGITTVLAMTTLLFGIQSSLPGVPYIKAVDQ-----FLIVSFACVFVAL 246
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO43147 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZH2])

HSP 1 Score: 60.077 bits (144), Expect = 3.784e-10
Identity = 60/264 (22.73%), Postives = 114/264 (43.18%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNYIDNQDLSS-----YWNPKIAISNIFVETKSLVSRE--VVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCI 1068
             K++ +  +NE    +S +IF    W EP     NY +   ++      +W P     N        V++E   +    SG  Y S   ++  T Q  + LQ FP D Q   + + +  ++ +++K    P     +  I    S E + F  V+  ++ I      G   + +  F+ +  R+ +YF I     + +  +L++  F I       R+SL +T +L+++     V+  +PK+ Y+  +D  +LGN   I ++ I
Sbjct:   34 FKVVSLGGINEASMEFSMDIFFRQWWHEPRFTH-NYSEPFTMAEDAGKLFWIPDTYFINAKKSNFHKVTKENARIIIYPSGNVYYS--VRLTLTLQCNMNLQLFPMDVQACPLFIESYAYTSEDIKYKWTPRGTKGIEII----SNETAQFVLVEARTEQIATAKISGHFSQLVATFSLK--RRLEYFAITVVTPAMILVVLSWCCFWIVPDAIPARISLSVTTILSTLLLSGTVNAQMPKVSYMKAIDVFVLGNFAFIFLSLI 288
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO48848 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHH0])

HSP 1 Score: 59.6918 bits (143), Expect = 5.351e-10
Identity = 58/262 (22.14%), Postives = 121/262 (46.18%), Query Frame = 1 
Query:  346 YSGEIFLEAKWREPLLDQ----SNYIDNQDLSSYWNPKIAISNIFVETKSLVSRE--VVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSL-----FNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWL 1095
            Y+ +IFL   W +  L      + ++ N  +   W P     N    +   V+++  +V     G+   + +  +RA+    + L+ FP D Q   +T+ +  +S D +        K ++   DG+     SL     +   +V    + N+Y +G+      +FT    R + YF+I+ +   ++  ++++ SF +       R++L +T +LT VT    ++ ++PK+ Y+  +DK ++G  + +  T + ++L  LWL
Sbjct:    8 YTLDIFLRQSWVDERLSHDLNTTMFLSNTVMDKIWLPDSYFVNAKQGSFHKVTKDNMMVMIQPDGQVQYNARVTIRASCP--MNLRKFPMDTQHCPLTLESYGYSSDHIVF------KWEIEDGDGLGFVPESLKMLPQYKLARVHLSTLHNEYVVGNWSGIKALFTFE--RMYSYFVIHVYGPCALIVVVSWVSFLLPKEQAPARITLGVTSVLTVVTILNMLNNSMPKVNYVKTIDKYLIGCFLFVFATLVEYSLV-LWL 258
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: gabrb1 (gamma-aminobutyric acid type A receptor beta1 subunit [Source:NCBI gene;Acc:101154825])

HSP 1 Score: 79.337 bits (194), Expect = 1.480e-15
Identity = 62/294 (21.09%), Postives = 134/294 (45.58%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMF-ECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF----HLSNNEATTALKN 1137
            + I  ID V+EV   Y+  ++ +  WR+  L  +       +DN+     W P       F+  K      V   N+      +  +    ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ + +   N   V  ++ ++  ++S+ ++  + +K +   +  GS  R  + F  +  R   YF++  +M S++  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F    HL    A  A  N
Sbjct:   64 IDIASIDMVSEVNMDYTITMYFQQSWRDKRLSYTGIPLNLTLDNRVADQLWVP----DTYFINDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWQGGSNAGSVTGVENIELPQFSIIDYQTLSTKAV---FATGSYPRLSLSFKLK--RNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGRGPHLQKKAAEKAKSN 348
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: gabrb2a (gamma-aminobutyric acid type A receptor beta2 subunit [Source:NCBI gene;Acc:101165154])

HSP 1 Score: 74.3294 bits (181), Expect = 6.676e-14
Identity = 60/276 (21.74%), Postives = 130/276 (47.10%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N   + KS V   V   N+      +  +    ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F     +  V+ +D ++  ++S+ ++  +   ++   ++ GS  R  + F  +  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   63 IDISSIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIAYNLTLDNRVADQLWVPDTYFLN---DKKSFV-HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWRGGEGAVSGVDRIELPQFSIVDYKLISKNVV---FSTGSYPRLSLSFKLK--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 328
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: gabrb2a (gamma-aminobutyric acid type A receptor beta2 subunit [Source:NCBI gene;Acc:101165154])

HSP 1 Score: 74.3294 bits (181), Expect = 7.593e-14
Identity = 60/276 (21.74%), Postives = 130/276 (47.10%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANK----SGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N   + KS V   V   N+      +  +    ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F     +  V+ +D ++  ++S+ ++  +   ++   ++ GS  R  + F  +  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   34 IDISSIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIAYNLTLDNRVADQLWVPDTYFLN---DKKSFV-HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWRGGEGAVSGVDRIELPQFSIVDYKLISKNVV---FSTGSYPRLSLSFKLK--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 299
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: GABRB2 (gamma-aminobutyric acid receptor subunit beta-2 [Source:NCBI gene;Acc:101167169])

HSP 1 Score: 72.7886 bits (177), Expect = 2.309e-13
Identity = 58/275 (21.09%), Postives = 127/275 (46.18%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F        V  ++ ++  ++S+ +H  +   ++   ++ G+  R  + F  +  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWRGGVGAVTGVERIELPQFSIVDHKLISKNVV---FSTGAYPRLSLSFKLK--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYIFF 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: GABRB2 (gamma-aminobutyric acid receptor subunit beta-2 [Source:NCBI gene;Acc:101167169])

HSP 1 Score: 72.7886 bits (177), Expect = 2.440e-13
Identity = 58/275 (21.09%), Postives = 127/275 (46.18%), Query Frame = 1 
Query:  310 LKILKIDTVNEV---YSGEIFLEAKWREPLLDQSNY-----IDNQDLSSYWNPKIAISN---IFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVAT-DHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLF 1098
            + I  ID V+EV   Y+  ++ +  WR+  L  S       +DN+     W P     N    FV   ++ +R +         Y     ++  T    ++L+ +P D Q+ ++ + +  ++ D+++ F        V  ++ ++  ++S+ +H  +   ++   ++ G+  R  + F  +  R   YF++  +M S +  +L++ SF I    +  R++L +T +LT  T    + + LPKIPY+  +D  ++G  + + +  + +A  +   F
Sbjct:   62 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY---GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE-FYWRGGVGAVTGVERIELPQFSIVDHKLISKNVV---FSTGAYPRLSLSFKLK--RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYIFF 327
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000041914.1 (SMESG000041914.1)

HSP 1 Score: 682.559 bits (1760), Expect = 0.000e+0
Identity = 355/357 (99.44%), Postives = 356/357 (99.72%), Query Frame = 1 
Query:  244 MENKAFVIEIPAPRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNIESXXXXXXXXXXXXXXXXXXXXXXFDAGKRRREMKGKDIEFNRALDKILMAKSSCDIC 1314
            MENKAFVIEIPAPRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKS VNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNIESGIIPAILIFYLIALLIFGLIIYFDAGKRRREMKGKDIEFNRALDKIL+AKSSCDIC
Sbjct:    1 MENKAFVIEIPAPRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSTVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNIESGIIPAILIFYLIALLIFGLIIYFDAGKRRREMKGKDIEFNRALDKILIAKSSCDIC 357
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000041914.1 (SMESG000041914.1)

HSP 1 Score: 657.522 bits (1695), Expect = 0.000e+0
Identity = 344/349 (98.57%), Postives = 345/349 (98.85%), Query Frame = 1 
Query:  268 EIPAPRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNIESXXXXXXXXXXXXXXXXXXXXXXFDAGKRRREMKGKDIEFNRALDKILMAKSSCDIC 1314
            EI   RQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKS VNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNIESGIIPAILIFYLIALLIFGLIIYFDAGKRRREMKGKDIEFNRALDKIL+AKSSCDIC
Sbjct:   28 EILFSRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSTVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNIESGIIPAILIFYLIALLIFGLIIYFDAGKRRREMKGKDIEFNRALDKILIAKSSCDIC 376
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000041829.1 (SMESG000041829.1)

HSP 1 Score: 453.751 bits (1166), Expect = 1.328e-158
Identity = 230/362 (63.54%), Postives = 288/362 (79.56%), Query Frame = 1 
Query:  244 MENKAFVIEIPAPRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQV-TNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLW----LFHLSNNEATTALKNIESXXXXXXXXXXXXXXXXXXXXXXFDAGKRRREMKGKDIEFNRALDKILMAKSSCDIC 1314
            MEN +  +  P  R +YL+CVF+KI K+DTVNE YS EIFL++KWREPLLD  + I +  LSS+WNPKI+I NIF+ETKS +S EV ++ K+ EAYI+EKR+V   F+E LELQHFPFDCQDLS+TV+T++ I+EVKM ECPH+ SK+NTIDGM+SQEW+L+ HV+VESK ++ND NIG +ERQ + FTCRA+R+FKYFLIN+ MISSMF+LLTFTSF I   TNT+ RL LCMT LLTSVTFKVAVSQNLPKIPYLTYLDK ILGNI+MIM  CIWHA TSL+    +F  ++   TTA++ IE  +IP++++FY +A+L  GL IYFDAGKRRREM  KD+EF+  + KI   K  CD+C
Sbjct:    1 MENNSKSVNKPVARLVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMISSMFFLLTFTSFSIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEKLFCDVC 362
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000041912.1 (SMESG000041912.1)

HSP 1 Score: 434.491 bits (1116), Expect = 4.127e-151
Identity = 218/359 (60.72%), Postives = 277/359 (77.16%), Query Frame = 1 
Query:  244 MENKAFVIEIPAPRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTA--LKNIESXXXXXXXXXXXXXXXXXXXXXXFDAGKRRREMKGKDIEFNRALDKILMAKSSCDIC 1314
            M+  +  ++ P  + IYL+CVF+KILK+DTVNE+YSGEIFL+AKWREPLLD S    N D S YWNPK++ISNIF E K  +S E+  A ++G AYI EK+++RATF ETLELQHFPFDCQDLSV+V +D S +EVK+ ECPH+ SK+N +DGMDSQEW+L+ HVQVESKII N+ NIG ++R++++FTCRA RQF YF+IN FMISS+ +LLTFTSF +  +N++GRL+LC TVLLTSVTFKVAVS NLPKIPYLTYLDKTI GNI+MIM  CIWHA+TSLW    + N A     LK  E  +   I  FY+++++IFGL IY+D GK+RR+MK KD +F   + +IL     C+IC
Sbjct:    1 MDLDSVEVKCPTTKDIYLRCVFIKILKVDTVNELYSGEIFLQAKWREPLLDYSVETKNIDFSHYWNPKLSISNIFTENKITISNEISIAKETGRAYIVEKKRIRATFNETLELQHFPFDCQDLSVSVISDFSANEVKLNECPHDLSKLNVVDGMDSQEWNLYKHVQVESKIISNECNIGPEKREVMIFTCRATRQFTYFIINYFMISSLLFLLTFTSFSVPSSNSYGRLALCKTVLLTSVTFKVAVSHNLPKIPYLTYLDKTIYGNILMIMSICIWHAITSLWFTDPTVNTAIGMNNLKPTEMIVALTIASFYVLSVMIFGLTIYYDVGKQRRKMKQKDKDFENKIKQILDENIFCEIC 359
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000064433.1 (SMESG000064433.1)

HSP 1 Score: 428.713 bits (1101), Expect = 7.644e-149
Identity = 221/344 (64.24%), Postives = 275/344 (79.94%), Query Frame = 1 
Query:  289 IYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLWL--FHLSNNEATTALKNIESXXXXXXXXXXXXXXXXXXXXXXFDAGKRRREMKGKDIEFNRALDKILMAKSSCDIC 1314
            +YL+CVF+KI K+DTVNE YSGEIFL++KWREPLLD    + + +L S+WNPK+ I NIF E KS VS EV F  K  EA+I EKR+V+A+F+ETLELQHFPFDCQDLSV+VAT++SIDEV + E P++ SK+NT+DG++SQEW+L+ HV+VE+K ++ND NIG KERQI+ FTCRA+R+FKYFLIN+F+ISSMF+LLTFTSF I  + T+GRL+LCMT LLTSVTFKVAVSQNLPKIPYLTYLDKTILGNI+ IM+ C WHA TS +     +S+  AT  +K +E+ II   L  Y + +LIFGL+IYFDAG RRREM  KD EF R L+KI   K  CD+C
Sbjct:   16 VYLRCVFVKIYKVDTVNEFYSGEIFLQSKWREPLLDHKPNLKDVNLFSFWNPKLIIENIFTENKSSVSLEVTFTEKY-EAFIIEKRRVKASFRETLELQHFPFDCQDLSVSVATEYSIDEVDLVETPNDVSKLNTLDGIESQEWNLYEHVEVEAKTMINDCNIGPKERQIMTFTCRASRRFKYFLINHFLISSMFFLLTFTSFSIPPSPTYGRLALCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNILFIMLLCFWHASTSFFFNDTTISSATATANVKQVETYIISCFLGVYGLVILIFGLVIYFDAGSRRREMSDKDREFKRLLEKIENEKLFCDVC 358
The following BLAST results are available for this feature:
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GABRB36.835e-1421.82gamma-aminobutyric acid type A receptor beta3 subu... [more]
GABRB38.277e-1421.82gamma-aminobutyric acid type A receptor beta3 subu... [more]
GABRB38.521e-1421.82gamma-aminobutyric acid type A receptor beta3 subu... [more]
GABRB39.257e-1421.82gamma-aminobutyric acid type A receptor beta3 subu... [more]
GABRB11.071e-1321.09gamma-aminobutyric acid type A receptor beta1 subu... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
avr-159.820e-1023.37pep chromosome:WBcel235:V:13498786:13502743:-1 gen... [more]
avr-159.820e-1023.37pep chromosome:WBcel235:V:13498786:13502582:-1 gen... [more]
avr-152.078e-923.37pep chromosome:WBcel235:V:13498786:13511718:-1 gen... [more]
glc-25.080e-824.80Glutamate-gated chloride channel subunit beta [So... [more]
lgc-313.542e-727.20Ligand-Gated ion Channel [Source:UniProtKB/TrEMBL... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG89161.085e-922.58gene:FBgn0030707 transcript:FBtr0301233[more]
CG89161.836e-923.11gene:FBgn0030707 transcript:FBtr0301232[more]
HisCl12.862e-923.19gene:FBgn0037950 transcript:FBtr0082470[more]
HisCl13.095e-923.19gene:FBgn0037950 transcript:FBtr0082471[more]
CG69273.973e-723.08gene:FBgn0029733 transcript:FBtr0070721[more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gabrb11.479e-1521.50gamma-aminobutyric acid type A receptor beta1 subu... [more]
gabrb43.107e-1321.74gamma-aminobutyric acid type A receptor beta4 subu... [more]
gabrb44.349e-1321.74gamma-aminobutyric acid type A receptor beta4 subu... [more]
gabrb32.713e-1220.36gamma-aminobutyric acid type A receptor beta3 subu... [more]
gabrb32.713e-1220.36gamma-aminobutyric acid type A receptor beta3 subu... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000004017.18.329e-1521.45gamma-aminobutyric acid (GABA) A receptor, beta 1 ... [more]
ENSXETT00000020832.14.222e-1421.01gamma-aminobutyric acid type A receptor theta subu... [more]
ENSXETT00000020814.14.480e-1421.01gamma-aminobutyric acid type A receptor theta subu... [more]
gabrb21.259e-1321.82gamma-aminobutyric acid (GABA) A receptor, beta 2 ... [more]
gabrb21.314e-1321.82gamma-aminobutyric acid (GABA) A receptor, beta 2 ... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gabrb35.413e-1421.82gamma-aminobutyric acid (GABA) A receptor, subunit... [more]
Gabrb35.957e-1421.82gamma-aminobutyric acid (GABA) A receptor, subunit... [more]
Gabrb37.396e-1421.82gamma-aminobutyric acid (GABA) A receptor, subunit... [more]
Gabrb17.417e-1421.09gamma-aminobutyric acid (GABA) A receptor, subunit... [more]
Gabrb24.325e-1321.74gamma-aminobutyric acid (GABA) A receptor, subunit... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P28472|GBRB3_HUMAN3.282e-1321.82Gamma-aminobutyric acid receptor subunit beta-3 OS... [more]
sp|P63079|GBRB3_RAT3.786e-1321.82Gamma-aminobutyric acid receptor subunit beta-3 OS... [more]
sp|P63080|GBRB3_MOUSE3.786e-1321.82Gamma-aminobutyric acid receptor subunit beta-3 OS... [more]
sp|P08220|GBRB1_BOVIN4.704e-1321.09Gamma-aminobutyric acid receptor subunit beta-1 OS... [more]
sp|P15431|GBRB1_RAT5.097e-1321.09Gamma-aminobutyric acid receptor subunit beta-1 OS... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0RSR92.691e-7141.53Uncharacterized protein OS=Fasciola hepatica OX=61... [more]
A0A3R7CFX93.038e-7140.22Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
A0A075A8W66.070e-7140.70Uncharacterized protein OS=Opisthorchis viverrini ... [more]
A0A5K4FCR61.426e-6741.27Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A2H1C9P41.872e-6739.74Uncharacterized protein OS=Fasciola hepatica OX=61... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gabrb12.207e-1521.50gamma-aminobutyric acid type A receptor beta1 subu... [more]
GABRB21.083e-1321.09gamma-aminobutyric acid receptor subunit beta-2 [S... [more]
GABRB21.336e-1321.09gamma-aminobutyric acid receptor subunit beta-2 [S... [more]
gabrb2a2.748e-1321.09gamma-aminobutyric acid type A receptor beta2 subu... [more]
gabrb2a2.810e-1321.09gamma-aminobutyric acid type A receptor beta2 subu... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
gabrb32.128e-1021.05gamma-aminobutyric acid type A receptor beta3 subu... [more]
ENSPMAT00000008467.12.774e-1022.43pep scaffold:Pmarinus_7.0:GL477211:8305:20106:1 ge... [more]
glra21.757e-923.79glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
gabrb34.964e-923.08gamma-aminobutyric acid type A receptor beta3 subu... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO327903.560e-2728.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO373967.462e-1122.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO400092.328e-1021.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO431473.784e-1022.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO488485.351e-1022.14Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gabrb11.480e-1521.09gamma-aminobutyric acid type A receptor beta1 subu... [more]
gabrb2a6.676e-1421.74gamma-aminobutyric acid type A receptor beta2 subu... [more]
gabrb2a7.593e-1421.74gamma-aminobutyric acid type A receptor beta2 subu... [more]
GABRB22.309e-1321.09gamma-aminobutyric acid receptor subunit beta-2 [S... [more]
GABRB22.440e-1321.09gamma-aminobutyric acid receptor subunit beta-2 [S... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000041914.10.000e+099.44SMESG000041914.1[more]
SMESG000041914.10.000e+098.57SMESG000041914.1[more]
SMESG000041829.11.328e-15863.54SMESG000041829.1[more]
SMESG000041912.14.127e-15160.72SMESG000041912.1[more]
SMESG000064433.17.644e-14964.24SMESG000064433.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003563 ID=SMED30003563|Name=Neur_chan_LBD domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1389bp
GAAAAATGTTTCAAATGTTATTGTCAAATTTTTAACACCATTAAAACATT
TTTGACAAATTGAAGGCTATAAAATATCAGACACAAAACACAAATAGTGC
AAGTTTATAATACAAAAACAAGTTCTCAATGAGTGTTATAAATTTAAGCA
CAACAAAGCTTAATTGATAAAATATATTGAAATAAGGTACTTCACGAACA
ATAAAAGGATTTTGGTAAAGAAAACAAATGCTAACCATTTGAAATGGAAA
ATAAGGCTTTTGTAATTGAAATCCCAGCACCAAGACAAATATATTTAAAA
TGTGTATTTTTAAAAATTCTCAAAATTGATACTGTAAATGAAGTTTATTC
TGGAGAAATATTTCTCGAAGCTAAATGGAGAGAGCCTTTATTGGACCAAA
GTAATTATATTGATAACCAAGATCTTTCTTCATATTGGAATCCAAAGATC
GCAATATCAAACATATTTGTTGAAACTAAATCTCTTGTGTCACGAGAAGT
TGTATTTGCAAATAAGTCTGGTGAAGCTTATATTTCAGAAAAAAGAAAGG
TACGTGCTACTTTTCAAGAAACGTTAGAATTGCAGCATTTCCCTTTTGAC
TGTCAAGATTTGTCTGTAACTGTTGCAACCGACCACTCCATTGACGAAGT
CAAAATGTTTGAATGTCCACATAATAAAAGTAAAGTAAATACAATCGACG
GAATGGATTCGCAAGAGTGGAGTCTGTTTAATCATGTTCAGGTTGAGAGT
AAAATTATATTGAATGATTACAATATTGGATCCAAAGAGCGTCAAATAAT
TGTATTCACATGTCGCGCAGCTCGTCAATTTAAATATTTTCTCATTAATA
ATTTCATGATCAGCTCAATGTTTTATTTGCTAACATTTACCAGTTTTGGA
ATACAAGTTACAAATACGTTCGGACGTTTGTCATTATGCATGACTGTCTT
ATTAACCAGTGTAACATTTAAAGTAGCAGTAAGTCAAAATCTTCCAAAAA
TTCCTTATTTAACATATTTGGATAAAACTATTCTGGGAAACATTATAATG
ATAATGATAACATGTATATGGCATGCTTTGACGTCCTTGTGGTTGTTTCA
CTTAAGCAATAATGAAGCTACAACAGCTCTAAAAAATATTGAGAGTGGAA
TAATTCCAGCAATCCTAATCTTCTATCTTATAGCTTTACTGATATTTGGA
TTAATTATTTACTTTGATGCCGGAAAAAGACGGAGGGAAATGAAAGGAAA
GGATATTGAATTTAATAGAGCATTGGATAAAATTCTTATGGCGAAATCTT
CATGTGATATTTGTTAACTGTTCAATGTTTTTATTTTAATATAACAAATA
AGTTTACAAATAATATTTTGAGAAACGCTTGTAAAAAAA
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protein sequence of SMED30003563-orf-1

>SMED30003563-orf-1 ID=SMED30003563-orf-1|Name=SMED30003563-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=358bp
MENKAFVIEIPAPRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLL
DQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEK
RKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSKVNT
IDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFL
INNFMISSMFYLLTFTSFGIQVTNTFGRLSLCMTVLLTSVTFKVAVSQNL
PKIPYLTYLDKTILGNIIMIMITCIWHALTSLWLFHLSNNEATTALKNIE
SGIIPAILIFYLIALLIFGLIIYFDAGKRRREMKGKDIEFNRALDKILMA
KSSCDIC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004888transmembrane signaling receptor activity
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR036734Neur_chan_lig-bd_sf
IPR006201Neur_channel
IPR036719Neuro-gated_channel_TM_sf
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
GO:0034220ion transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 15..188
e-value: 3.4E-6
score: 26.7
NoneNo IPR availableGENE3DG3DSA:1.20.58.390coord: 193..338
e-value: 9.1E-16
score: 59.9
NoneNo IPR availablePANTHERPTHR18945:SF768coord: 12..280
NoneNo IPR availableCDDcd18988LGIC_ECD_bactcoord: 22..195
e-value: 2.9517E-14
score: 68.0882
NoneNo IPR availableCDDcd19050LGIC_TM_bactcoord: 198..318
e-value: 2.86458E-10
score: 55.2922
NoneNo IPR availableTMHMMTMhelixcoord: 198..220
NoneNo IPR availableTMHMMTMhelixcoord: 302..324
NoneNo IPR availableTMHMMTMhelixcoord: 224..246
NoneNo IPR availableTMHMMTMhelixcoord: 265..287
IPR036734Neurotransmitter-gated ion-channel ligand-binding domain superfamilyGENE3DG3DSA:2.70.170.10coord: 11..188
e-value: 2.9E-17
score: 64.8
IPR036734Neurotransmitter-gated ion-channel ligand-binding domain superfamilySUPERFAMILYSSF63712Nicotinic receptor ligand binding domain-likecoord: 12..173
IPR006201Neurotransmitter-gated ion-channelPANTHERPTHR18945NEUROTRANSMITTER GATED ION CHANNELcoord: 12..280
IPR036719Neurotransmitter-gated ion-channel transmembrane domain superfamilySUPERFAMILYSSF90112Neurotransmitter-gated ion-channel transmembrane porecoord: 198..286